A616_RS32085 20b610b9737ecbb4f10688a7c5fd760f 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 8.4E-62 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS32085 20b610b9737ecbb4f10688a7c5fd760f 159 SUPERFAMILY SSF75217 1 157 1.31E-59 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS32085 20b610b9737ecbb4f10688a7c5fd760f 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 6.1E-62 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS32085 20b610b9737ecbb4f10688a7c5fd760f 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 31.228 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS32085 20b610b9737ecbb4f10688a7c5fd760f 159 PIRSF PIRSF004505 1 159 1.1E-55 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS32085 20b610b9737ecbb4f10688a7c5fd760f 159 Gene3D G3DSA:3.40.1280.10 1 159 9.0E-64 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 SMART SM00490 435 512 8.5E-7 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 Gene3D G3DSA:3.40.50.300 392 538 1.2E-17 T 29-03-2018 A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 Gene3D G3DSA:3.40.50.300 174 366 5.8E-25 T 29-03-2018 A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 SUPERFAMILY SSF52540 302 340 9.06E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 SUPERFAMILY SSF52540 386 538 9.06E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 SMART SM00487 183 360 1.3E-19 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 365 552 1.5E-51 T 29-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 Pfam PF13625 Helicase conserved C-terminal domain 12 133 4.7E-39 T 29-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 Pfam PF04851 Type III restriction enzyme, res subunit 185 338 9.3E-13 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A616_RS22345 d74a693f9fdea2becbd4a2e80fb71a2f 557 SUPERFAMILY SSF52540 135 357 5.43E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 23 129 3.4E-28 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 221 346 3.0E-10 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 5.6E-5 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 SMART SM00839 144 351 1.2E-65 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 Gene3D G3DSA:3.40.50.720 145 358 3.5E-35 T 29-03-2018 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 Gene3D G3DSA:3.40.50.10860 1 144 4.1E-53 T 29-03-2018 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 SUPERFAMILY SSF53223 4 143 3.2E-49 T 29-03-2018 A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 SUPERFAMILY SSF51735 141 350 2.9E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13265 e08d6ab6b533e9c1fb6b4c9378640de5 363 PIRSF PIRSF000188 1 353 3.9E-163 T 29-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 A616_RS23220 5c76ae15af6c0341afb6ed637d6b18c9 241 Gene3D G3DSA:2.10.25.20 181 237 9.3E-6 T 29-03-2018 A616_RS23220 5c76ae15af6c0341afb6ed637d6b18c9 241 SUPERFAMILY SSF69255 18 97 1.6E-20 T 29-03-2018 A616_RS23220 5c76ae15af6c0341afb6ed637d6b18c9 241 Gene3D G3DSA:2.40.50.260 15 123 1.6E-28 T 29-03-2018 A616_RS23220 5c76ae15af6c0341afb6ed637d6b18c9 241 SUPERFAMILY SSF69349 87 241 1.65E-9 T 29-03-2018 A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SMART SM00052 464 705 2.9E-125 T 29-03-2018 IPR001633 EAL domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 292 452 3.3E-47 T 29-03-2018 IPR000160 GGDEF domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Gene3D G3DSA:3.30.70.270 293 457 4.5E-65 T 29-03-2018 A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Gene3D G3DSA:3.30.450.20 173 292 9.1E-26 T 29-03-2018 A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Gene3D G3DSA:3.30.450.20 150 172 0.0043 T 29-03-2018 A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SUPERFAMILY SSF55073 299 455 1.8E-54 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Pfam PF00563 EAL domain 472 700 3.5E-75 T 29-03-2018 IPR001633 EAL domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SMART SM00267 283 454 2.2E-73 T 29-03-2018 IPR000160 GGDEF domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Pfam PF00989 PAS fold 172 280 1.8E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SMART SM00086 116 159 480.0 T 29-03-2018 IPR001610 PAC motif A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SMART SM00086 242 283 0.0086 T 29-03-2018 IPR001610 PAC motif A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SUPERFAMILY SSF55785 45 160 8.55E-7 T 29-03-2018 IPR000014 PAS domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Gene3D G3DSA:3.30.450.20 35 149 4.4E-11 T 29-03-2018 A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 168 289 1.7E-23 T 29-03-2018 IPR000014 PAS domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 39 166 1.4E-6 T 29-03-2018 IPR000014 PAS domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SUPERFAMILY SSF141868 471 712 8.63E-90 T 29-03-2018 IPR001633 EAL domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Pfam PF00990 Diguanylate cyclase, GGDEF domain 294 450 3.5E-55 T 29-03-2018 IPR000160 GGDEF domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SUPERFAMILY SSF55785 156 281 2.27E-24 T 29-03-2018 IPR000014 PAS domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Gene3D G3DSA:3.20.20.450 463 716 1.2E-100 T 29-03-2018 IPR001633 EAL domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SMART SM00091 171 237 2.8E-8 T 29-03-2018 IPR000014 PAS domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 SMART SM00091 40 108 110.0 T 29-03-2018 IPR000014 PAS domain A616_RS03585 99d4bfaa77dc7dc000aad343eabe8628 716 Pfam PF13426 PAS domain 52 158 0.97 T 29-03-2018 IPR000014 PAS domain A616_RS24880 6109f272d568dd059a18478dcfa64f44 474 Gene3D G3DSA:1.10.10.660 98 162 2.1E-32 T 29-03-2018 IPR024033 Uncharacterised domain, YlbE A616_RS24880 6109f272d568dd059a18478dcfa64f44 474 Gene3D G3DSA:3.90.1710.10 163 304 5.5E-60 T 29-03-2018 A616_RS24880 6109f272d568dd059a18478dcfa64f44 474 Gene3D G3DSA:3.90.1700.10 307 470 8.9E-71 T 29-03-2018 A616_RS24880 6109f272d568dd059a18478dcfa64f44 474 Pfam PF06545 Protein of unknown function (DUF1116) 145 360 1.5E-90 T 29-03-2018 IPR009499 Protein of unknown function DUF1116 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 Gene3D G3DSA:2.30.30.30 119 195 1.1E-33 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 SMART SM01382 124 253 8.3E-92 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 SMART SM01383 42 118 8.4E-49 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 SUPERFAMILY SSF50249 3 125 1.06E-53 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS01415 0ff46a366b5094379378ebda305a2622 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 1.1E-56 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 Gene3D G3DSA:4.10.950.10 197 275 2.6E-35 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 5.8E-140 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 SUPERFAMILY SSF50104 126 273 1.56E-60 T 29-03-2018 IPR008991 Translation protein SH3-like domain A616_RS01415 0ff46a366b5094379378ebda305a2622 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 PIRSF PIRSF002158 3 276 2.5E-100 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 6.0E-36 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 Gene3D G3DSA:2.40.50.140 1 114 2.1E-52 T 29-03-2018 A616_RS01415 0ff46a366b5094379378ebda305a2622 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.194 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A616_RS31685 37292f8e988cc1ecece46728eb1282b8 630 Gene3D G3DSA:3.40.710.10 22 387 2.8E-82 T 29-03-2018 A616_RS31685 37292f8e988cc1ecece46728eb1282b8 630 Pfam PF00144 Beta-lactamase 43 362 3.4E-64 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS31685 37292f8e988cc1ecece46728eb1282b8 630 SUPERFAMILY SSF56601 38 365 3.04E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS23000 9121dd21a03e02fc7371fcd4dd219b9c 108 Pfam PF11009 Protein of unknown function (DUF2847) 5 102 8.3E-34 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 A616_RS23000 9121dd21a03e02fc7371fcd4dd219b9c 108 Gene3D G3DSA:3.40.30.10 3 104 1.3E-35 T 29-03-2018 A616_RS23000 9121dd21a03e02fc7371fcd4dd219b9c 108 SUPERFAMILY SSF52833 2 94 5.44E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS23000 9121dd21a03e02fc7371fcd4dd219b9c 108 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 5 103 4.3E-35 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 A616_RS30195 144e836b42e8a141edfedaa257955433 472 SUPERFAMILY SSF52540 153 396 1.42E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30195 144e836b42e8a141edfedaa257955433 472 Gene3D G3DSA:1.10.8.60 340 394 5.5E-24 T 29-03-2018 A616_RS30195 144e836b42e8a141edfedaa257955433 472 Pfam PF00158 Sigma-54 interaction domain 155 318 6.8E-63 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS30195 144e836b42e8a141edfedaa257955433 472 SMART SM00091 8 76 1.5E-8 T 29-03-2018 IPR000014 PAS domain A616_RS30195 144e836b42e8a141edfedaa257955433 472 Pfam PF00989 PAS fold 8 82 3.1E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS30195 144e836b42e8a141edfedaa257955433 472 SUPERFAMILY SSF55785 8 111 1.36E-14 T 29-03-2018 IPR000014 PAS domain A616_RS30195 144e836b42e8a141edfedaa257955433 472 Gene3D G3DSA:3.30.450.20 2 129 5.9E-16 T 29-03-2018 A616_RS30195 144e836b42e8a141edfedaa257955433 472 Pfam PF02954 Bacterial regulatory protein, Fis family 427 465 8.8E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS30195 144e836b42e8a141edfedaa257955433 472 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 127 1.8E-12 T 29-03-2018 IPR000014 PAS domain A616_RS30195 144e836b42e8a141edfedaa257955433 472 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 239 254 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS30195 144e836b42e8a141edfedaa257955433 472 Gene3D G3DSA:1.10.10.60 395 469 4.9E-18 T 29-03-2018 A616_RS30195 144e836b42e8a141edfedaa257955433 472 SUPERFAMILY SSF46689 366 466 4.3E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30195 144e836b42e8a141edfedaa257955433 472 SMART SM00382 174 316 1.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30195 144e836b42e8a141edfedaa257955433 472 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 178 191 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS30195 144e836b42e8a141edfedaa257955433 472 Gene3D G3DSA:3.40.50.300 130 339 1.8E-30 T 29-03-2018 A616_RS30195 144e836b42e8a141edfedaa257955433 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 450 3.6E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS30195 144e836b42e8a141edfedaa257955433 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 450 470 3.6E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS30195 144e836b42e8a141edfedaa257955433 472 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 SMART SM00382 349 514 4.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 SMART SM00382 28 231 4.8E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 SUPERFAMILY SSF52540 310 516 2.47E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 Pfam PF12848 ABC transporter 230 314 2.3E-27 T 29-03-2018 IPR032781 ABC-transporter extension domain A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 Gene3D G3DSA:3.40.50.300 1 291 7.3E-50 T 29-03-2018 A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 Pfam PF00005 ABC transporter 20 191 8.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 Pfam PF00005 ABC transporter 342 468 6.5E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 SUPERFAMILY SSF52540 4 244 4.18E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS18985 efaabd118e65c9918c3b5209b8993c1a 523 Gene3D G3DSA:3.40.50.300 292 523 4.0E-39 T 29-03-2018 A616_RS02955 ac3b219b95ac8c0d886469ebad4d48d1 151 Gene3D G3DSA:3.40.630.30 1 151 2.7E-33 T 29-03-2018 A616_RS02955 ac3b219b95ac8c0d886469ebad4d48d1 151 SUPERFAMILY SSF55729 6 151 2.74E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS02955 ac3b219b95ac8c0d886469ebad4d48d1 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 17 147 5.3E-42 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A616_RS02955 ac3b219b95ac8c0d886469ebad4d48d1 151 Pfam PF00583 Acetyltransferase (GNAT) family 20 127 5.8E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 108 116 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 133 148 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 286 300 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 209 222 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 399 412 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 343 354 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 119 132 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 195 208 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 PRINTS PR00415 Aconitase family signature 82 95 9.8E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 466 59.615 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 Gene3D G3DSA:3.40.1060.10 155 288 8.1E-41 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 Gene3D G3DSA:3.30.499.10 1 154 1.4E-42 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 Gene3D G3DSA:3.30.499.10 324 476 9.2E-54 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 Pfam PF00330 Aconitase family (aconitate hydratase) 8 457 2.8E-158 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 SUPERFAMILY SSF53732 3 467 8.89E-166 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14110 ddbb21469236169f24dea9d0c765a8ee 476 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 464 3.6E-238 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 Pfam PF02926 THUMP domain 15 155 1.2E-14 T 29-03-2018 IPR004114 THUMP domain GO:0003723 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 1.4E-60 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 SMART SM00981 58 155 1.1E-11 T 29-03-2018 IPR004114 THUMP domain GO:0003723 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 Gene3D G3DSA:3.40.50.150 161 374 7.2E-35 T 29-03-2018 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A616_RS30340 2f8f82fedac926d4027876433061cf22 385 SUPERFAMILY SSF53335 255 364 3.8E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS30340 2f8f82fedac926d4027876433061cf22 385 SUPERFAMILY SSF53335 144 218 3.8E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 Pfam PF00467 KOW motif 128 159 1.2E-7 T 29-03-2018 IPR005824 KOW A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 SMART SM00738 2 113 4.0E-54 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 Pfam PF02357 Transcription termination factor nusG 3 110 4.6E-30 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 Gene3D G3DSA:3.30.70.940 2 117 1.5E-45 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 9.1E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 9.1E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 9.1E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 SUPERFAMILY SSF50104 108 178 3.7E-17 T 29-03-2018 IPR008991 Translation protein SH3-like domain A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 2.4E-65 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 SMART SM00739 123 150 0.0011 T 29-03-2018 IPR005824 KOW A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 27.475 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 SUPERFAMILY SSF82679 2 113 2.35E-42 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS01315 83ba2dd71ec5ce14f420ea3230ee94a9 178 Gene3D G3DSA:2.30.30.30 119 177 1.2E-20 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 SUPERFAMILY SSF58104 232 266 2.75E-78 T 29-03-2018 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 SUPERFAMILY SSF58104 299 568 2.75E-78 T 29-03-2018 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 1.1E-23 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 420 449 1.1E-23 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 418 1.1E-23 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Gene3D G3DSA:1.20.120.30 24 185 5.6E-12 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Pfam PF00672 HAMP domain 214 260 4.5E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Gene3D G3DSA:1.10.287.950 317 506 1.7E-56 T 29-03-2018 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Gene3D G3DSA:1.10.287.950 210 316 4.8E-9 T 29-03-2018 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 520 6.9E-54 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 SMART SM00304 212 264 4.5E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 184 4.9E-36 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 SMART SM00283 293 568 4.9E-96 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS26200 15804cde9e701d5dd91930b8467c2402 570 Gene3D G3DSA:1.10.287.1060 507 568 0.28 T 29-03-2018 A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 Gene3D G3DSA:1.10.10.10 121 226 1.0E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 SUPERFAMILY SSF52172 3 179 4.84E-45 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 Pfam PF00072 Response regulator receiver domain 5 113 3.6E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 SMART SM00448 3 113 9.9E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 7.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 SMART SM00862 146 221 1.8E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS01965 b097f4c20961df22df652d7a490fbb34 226 Gene3D G3DSA:3.40.50.2300 1 120 7.3E-38 T 29-03-2018 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 2.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 2.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 2.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 2.1E-35 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 Gene3D G3DSA:3.30.420.10 1 162 1.5E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 148 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 SUPERFAMILY SSF53098 1 155 9.48E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 154 46.92 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 5.4E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS10650 9d1d51d77572a3cd531012ca3a267947 166 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 5.2E-53 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 Gene3D G3DSA:2.40.37.10 234 385 5.0E-58 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 Pfam PF01168 Alanine racemase, N-terminal domain 12 234 1.6E-67 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 Hamap MF_01201 Alanine racemase. 5 376 34.345 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 SUPERFAMILY SSF50621 246 382 1.74E-49 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 Pfam PF00842 Alanine racemase, C-terminal domain 250 375 4.8E-43 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 SMART SM01005 249 376 1.3E-63 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 Gene3D G3DSA:3.20.20.10 3 233 2.3E-52 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS02880 5ac782a4930174195e1005812793f7cb 400 SUPERFAMILY SSF51419 12 238 1.18E-64 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 358 371 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 31 47 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 282 297 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 164 175 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 67 85 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 265 280 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 207 234 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 303 320 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 PRINTS PR00992 Alanine racemase signature 129 141 4.2E-65 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS02880 5ac782a4930174195e1005812793f7cb 400 TIGRFAM TIGR00492 alr: alanine racemase 6 376 4.2E-129 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Gene3D G3DSA:3.90.199.10 32 213 6.4E-79 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 6 751 3.5E-253 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 SUPERFAMILY SSF101904 505 788 2.88E-64 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Gene3D G3DSA:3.30.1360.40 234 336 1.1E-27 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 511 530 1.3 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 717 760 1.4E-6 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 664 707 2.2E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 559 605 2.1 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 617 657 0.016 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 SUPERFAMILY SSF56719 29 490 2.35E-161 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Gene3D G3DSA:1.10.268.10 348 490 1.6E-43 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 470 6.4E-145 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 Gene3D G3DSA:2.120.10.90 505 823 5.5E-67 T 29-03-2018 A616_RS18855 9e526d13caed9e6d3706ada6f4a07fd6 847 SMART SM00434 9 468 4.6E-231 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS25620 e13d316a1133763a7d47cb03f8e6b549 308 SUPERFAMILY SSF161098 92 287 8.63E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25620 e13d316a1133763a7d47cb03f8e6b549 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 74 1.0E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS25620 e13d316a1133763a7d47cb03f8e6b549 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 307 5.2E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25620 e13d316a1133763a7d47cb03f8e6b549 308 Gene3D G3DSA:1.10.3720.10 27 296 2.8E-46 T 29-03-2018 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Pfam PF00970 Oxidoreductase FAD-binding domain 159 260 1.3E-8 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Pfam PF00175 Oxidoreductase NAD-binding domain 272 379 1.5E-16 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Gene3D G3DSA:3.40.50.80 261 405 1.4E-28 T 29-03-2018 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 185 195 1.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 271 290 1.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 206 213 1.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 366 374 1.7E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS06845 daa36871d4696038745c8969175f8f47 405 SUPERFAMILY SSF46458 1 143 4.99E-43 T 29-03-2018 IPR009050 Globin-like A616_RS06845 daa36871d4696038745c8969175f8f47 405 SUPERFAMILY SSF63380 151 262 1.38E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Gene3D G3DSA:2.40.30.10 160 260 2.6E-24 T 29-03-2018 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Hamap MF_01252 Flavohemoprotein [hmp]. 1 404 57.341 T 29-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Gene3D G3DSA:1.10.490.10 1 159 1.8E-45 T 29-03-2018 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00406 Cytochrome B5 reductase signature 366 374 7.8E-5 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00406 Cytochrome B5 reductase signature 248 262 7.8E-5 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 A616_RS06845 daa36871d4696038745c8969175f8f47 405 PRINTS PR00406 Cytochrome B5 reductase signature 271 290 7.8E-5 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 A616_RS06845 daa36871d4696038745c8969175f8f47 405 SUPERFAMILY SSF52343 263 401 4.45E-40 T 29-03-2018 A616_RS06845 daa36871d4696038745c8969175f8f47 405 Pfam PF00042 Globin 7 102 1.8E-10 T 29-03-2018 IPR000971 Globin GO:0020037 A616_RS16945 6749a8f193715ea390d3cdac41381443 125 Gene3D G3DSA:1.10.260.40 19 116 8.9E-20 T 29-03-2018 A616_RS16945 6749a8f193715ea390d3cdac41381443 125 SUPERFAMILY SSF47413 17 86 7.51E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS16945 6749a8f193715ea390d3cdac41381443 125 Pfam PF01381 Helix-turn-helix 27 77 2.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16945 6749a8f193715ea390d3cdac41381443 125 SMART SM00530 26 81 3.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 Gene3D G3DSA:1.10.260.40 5 77 6.1E-15 T 29-03-2018 A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 Pfam PF07883 Cupin domain 111 178 3.3E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 Pfam PF01381 Helix-turn-helix 12 62 2.5E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 SUPERFAMILY SSF47413 4 72 3.94E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 SUPERFAMILY SSF51182 59 185 2.02E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 Gene3D G3DSA:2.60.120.10 78 185 1.0E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS21370 5c0e47078ac76d0524286f3e8515696e 185 SMART SM00530 11 66 5.2E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS01940 e765124a7b6d964b0a4d914bdc8dd8c4 362 SUPERFAMILY SSF51735 5 139 9.71E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS01940 e765124a7b6d964b0a4d914bdc8dd8c4 362 Gene3D G3DSA:3.30.360.10 140 353 8.3E-5 T 29-03-2018 A616_RS01940 e765124a7b6d964b0a4d914bdc8dd8c4 362 Gene3D G3DSA:3.40.50.720 1 139 3.6E-15 T 29-03-2018 A616_RS01940 e765124a7b6d964b0a4d914bdc8dd8c4 362 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 6 117 1.5E-9 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Pfam PF07497 Rho termination factor, RNA-binding domain 51 123 4.1E-33 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 SMART SM00357 52 116 2.6E-18 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Gene3D G3DSA:1.10.720.10 1 43 4.7E-15 T 29-03-2018 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Gene3D G3DSA:2.40.50.140 49 104 4.6E-30 T 29-03-2018 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Gene3D G3DSA:3.40.50.300 105 362 4.7E-53 T 29-03-2018 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 SUPERFAMILY SSF68912 3 47 3.65E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 SMART SM00382 165 350 1.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 TIGRFAM TIGR00767 rho: transcription termination factor Rho 3 410 2.6E-203 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 SMART SM00959 5 47 1.3E-15 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 SUPERFAMILY SSF52540 88 366 3.23E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 155 358 6.9E-20 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 6.4E-16 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 413 222.343 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A616_RS30080 ff16f569b352e35004bb0fcd4d98eea2 426 SUPERFAMILY SSF50249 49 123 6.85E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 PIRSF PIRSF000151 2 422 1.7E-165 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 15 412 8.7E-151 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 SUPERFAMILY SSF53720 6 422 7.46E-108 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 350 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 Gene3D G3DSA:3.40.605.10 2 243 3.7E-35 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 Gene3D G3DSA:3.40.605.10 244 422 9.4E-42 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 Pfam PF00171 Aldehyde dehydrogenase family 5 282 4.5E-14 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS27005 747c0d008c94ad4f28f828714b1575f9 422 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 7 422 39.568 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS10535 a87eb20727db925b04100a95abc83d41 261 Gene3D G3DSA:2.70.70.10 134 260 2.0E-12 T 29-03-2018 A616_RS10535 a87eb20727db925b04100a95abc83d41 261 Pfam PF01551 Peptidase family M23 178 254 1.9E-9 T 29-03-2018 IPR016047 Peptidase M23 A616_RS10535 a87eb20727db925b04100a95abc83d41 261 SUPERFAMILY SSF51261 140 257 2.88E-11 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 Pfam PF13458 Periplasmic binding protein 57 401 7.7E-46 T 29-03-2018 IPR028081 Leucine-binding protein domain A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 SUPERFAMILY SSF53822 57 407 6.73E-76 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 Gene3D G3DSA:3.40.50.2300 183 311 1.3E-32 T 29-03-2018 A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 Gene3D G3DSA:3.40.50.2300 50 182 3.4E-14 T 29-03-2018 A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 Gene3D G3DSA:3.40.50.2300 312 390 1.2E-7 T 29-03-2018 A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 57 73 6.9E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 98 116 6.9E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS03635 6018af168c2a2ae79b3b6881d9035229 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 286 304 6.9E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 9.0E-40 T 29-03-2018 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 9.0E-40 T 29-03-2018 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 9.0E-40 T 29-03-2018 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 9.0E-40 T 29-03-2018 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 6.7E-142 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 PIRSF PIRSF001553 1 291 1.8E-129 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 Pfam PF02629 CoA binding domain 6 99 2.5E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 Gene3D G3DSA:3.40.50.261 120 299 1.1E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 Gene3D G3DSA:3.40.50.720 1 119 7.4E-42 T 29-03-2018 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 SUPERFAMILY SSF51735 1 122 4.63E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 SMART SM00881 4 100 3.2E-31 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 Pfam PF00549 CoA-ligase 151 266 1.0E-15 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 SUPERFAMILY SSF52210 123 288 3.53E-54 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20095 54046c73e161b9fe8b1b7429c80593dd 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 42.898 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS14810 e35dfb82e75b2e672541f3123e88ec6c 459 Gene3D G3DSA:3.40.630.10 7 201 1.1E-32 T 29-03-2018 A616_RS14810 e35dfb82e75b2e672541f3123e88ec6c 459 Gene3D G3DSA:3.30.70.360 202 367 2.6E-43 T 29-03-2018 A616_RS14810 e35dfb82e75b2e672541f3123e88ec6c 459 Pfam PF01546 Peptidase family M20/M25/M40 84 447 2.7E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS14810 e35dfb82e75b2e672541f3123e88ec6c 459 Pfam PF07687 Peptidase dimerisation domain 196 354 5.3E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS14810 e35dfb82e75b2e672541f3123e88ec6c 459 SUPERFAMILY SSF53187 4 198 2.4E-54 T 29-03-2018 A616_RS14810 e35dfb82e75b2e672541f3123e88ec6c 459 SUPERFAMILY SSF53187 368 454 2.4E-54 T 29-03-2018 A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 Gene3D G3DSA:3.40.50.150 84 153 6.6E-11 T 29-03-2018 A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 Gene3D G3DSA:3.40.50.150 158 458 9.8E-51 T 29-03-2018 A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 Pfam PF01938 TRAM domain 14 68 7.3E-13 T 29-03-2018 IPR002792 TRAM domain A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 442 452 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 Gene3D G3DSA:2.40.50.140 2 83 6.0E-24 T 29-03-2018 A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 SUPERFAMILY SSF50249 4 68 1.2E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 25 452 1.6E-157 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 98 457 2.1E-21 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 391 422 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site A616_RS05635 b0db4089447ecf978c2b866b48362f6e 460 SUPERFAMILY SSF53335 77 457 6.11E-81 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS02605 bba9653fe53637e7ff299b6313f8408a 349 Pfam PF12840 Helix-turn-helix domain 268 325 4.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02605 bba9653fe53637e7ff299b6313f8408a 349 SMART SM00418 268 345 2.6E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02605 bba9653fe53637e7ff299b6313f8408a 349 Gene3D G3DSA:1.10.10.10 247 336 9.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02605 bba9653fe53637e7ff299b6313f8408a 349 SUPERFAMILY SSF46785 261 344 1.36E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02605 bba9653fe53637e7ff299b6313f8408a 349 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 270 285 1.5E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02605 bba9653fe53637e7ff299b6313f8408a 349 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 302 317 1.5E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS25305 dfc7532c30d1555fc29fc4f1236deba0 268 Pfam PF13354 Beta-lactamase enzyme family 29 237 2.9E-57 T 29-03-2018 A616_RS25305 dfc7532c30d1555fc29fc4f1236deba0 268 SUPERFAMILY SSF56601 2 262 8.75E-42 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25305 dfc7532c30d1555fc29fc4f1236deba0 268 Gene3D G3DSA:3.40.710.10 2 267 1.5E-28 T 29-03-2018 A616_RS13145 99db365601711cbbdeb336dd41459be7 564 Pfam PF01432 Peptidase family M3 168 271 1.3E-6 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS13145 99db365601711cbbdeb336dd41459be7 564 Pfam PF01432 Peptidase family M3 314 535 1.6E-17 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS13145 99db365601711cbbdeb336dd41459be7 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 560 6.8E-210 T 29-03-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related A616_RS13145 99db365601711cbbdeb336dd41459be7 564 Gene3D G3DSA:1.10.1370.10 68 537 5.3E-60 T 29-03-2018 A616_RS13145 99db365601711cbbdeb336dd41459be7 564 SUPERFAMILY SSF55486 34 560 4.5E-118 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Gene3D G3DSA:1.10.1200.10 808 878 5.6E-20 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 SUPERFAMILY SSF52777 1062 1306 3.22E-53 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Pfam PF00501 AMP-binding enzyme 276 693 1.7E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 SUPERFAMILY SSF47336 797 869 2.22E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Gene3D G3DSA:3.30.300.30 688 807 1.9E-34 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Gene3D G3DSA:3.40.50.980 267 430 4.3E-49 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Gene3D G3DSA:3.40.50.980 431 585 6.6E-33 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 ProSitePatterns PS00012 Phosphopantetheine attachment site. 828 843 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 PIRSF PIRSF001617 417 741 1.5E-30 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 PIRSF PIRSF001617 738 905 3.9E-24 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 PIRSF PIRSF001617 17 382 1.4E-21 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 PIRSF PIRSF001617 1061 1317 2.8E-4 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 297 717 2.1E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Pfam PF13193 AMP-binding enzyme C-terminal domain 701 774 8.9E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Pfam PF00550 Phosphopantetheine attachment site 804 867 2.6E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 ProSitePatterns PS00455 Putative AMP-binding domain signature. 424 435 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Gene3D G3DSA:2.30.38.10 586 685 4.4E-21 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 SUPERFAMILY SSF56801 235 815 6.41E-154 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Gene3D G3DSA:3.30.559.10 881 1073 1.4E-38 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Pfam PF00668 Condensation domain 9 255 1.4E-28 T 29-03-2018 IPR001242 Condensation domain A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 Pfam PF00668 Condensation domain 888 1312 5.1E-107 T 29-03-2018 IPR001242 Condensation domain A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 SUPERFAMILY SSF52777 15 239 7.41E-28 T 29-03-2018 A616_RS18520 66dc12fa8aefd1843121d2ccc2e500e5 1327 SUPERFAMILY SSF52777 892 1054 2.45E-38 T 29-03-2018 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 Pfam PF02803 Thiolase, C-terminal domain 270 390 5.7E-51 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.3E-148 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 PIRSF PIRSF000429 1 392 5.3E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 Gene3D G3DSA:3.40.47.10 267 389 8.9E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 1.4E-79 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 SUPERFAMILY SSF53901 270 391 1.11E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 Gene3D G3DSA:3.40.47.10 1 266 8.0E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS26960 e7c25d80ed14f66367532e94c15c7aa5 392 SUPERFAMILY SSF53901 3 268 3.51E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 SUPERFAMILY SSF51338 16 80 3.57E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 SUPERFAMILY SSF51338 326 369 3.57E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 Gene3D G3DSA:2.30.40.10 281 361 2.3E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 Pfam PF13382 Adenine deaminase C-terminal domain 411 574 1.1E-31 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 Pfam PF01979 Amidohydrolase family 77 356 1.4E-14 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 SUPERFAMILY SSF51556 79 326 1.47E-12 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 Gene3D G3DSA:2.30.40.10 21 83 8.7E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS03630 9c26e6a55742426d60dd411279b6bc9e 585 Gene3D G3DSA:3.20.20.140 84 280 1.6E-5 T 29-03-2018 A616_RS09750 4136b539ea2e323f1a57086633a19d5b 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 249 3.1E-13 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A616_RS09750 4136b539ea2e323f1a57086633a19d5b 253 Pfam PF00005 ABC transporter 18 178 2.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09750 4136b539ea2e323f1a57086633a19d5b 253 SMART SM00382 27 226 4.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09750 4136b539ea2e323f1a57086633a19d5b 253 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS09750 4136b539ea2e323f1a57086633a19d5b 253 SUPERFAMILY SSF52540 2 250 2.93E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09750 4136b539ea2e323f1a57086633a19d5b 253 Gene3D G3DSA:3.40.50.300 1 253 3.9E-58 T 29-03-2018 A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 Pfam PF13411 MerR HTH family regulatory protein 2 70 3.4E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 SUPERFAMILY SSF46955 2 107 6.23E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 SMART SM00871 120 270 3.3E-11 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 SMART SM00422 2 72 1.7E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 SUPERFAMILY SSF55136 128 272 8.89E-14 T 29-03-2018 A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 Gene3D G3DSA:3.20.80.10 126 271 6.7E-23 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS05165 5dc996950b3d25dbd8f97cd7e03e0e03 275 Gene3D G3DSA:1.10.1660.10 1 125 1.6E-21 T 29-03-2018 A616_RS22080 ead8c249c7e89b00a1a6658e5879a1ad 276 Gene3D G3DSA:3.40.50.1820 4 259 8.0E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS22080 ead8c249c7e89b00a1a6658e5879a1ad 276 SUPERFAMILY SSF53474 15 203 2.37E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS22080 ead8c249c7e89b00a1a6658e5879a1ad 276 Pfam PF01764 Lipase (class 3) 71 201 6.5E-24 T 29-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A616_RS21490 024b104e42e159f229040e19e0145a9d 395 Gene3D G3DSA:3.40.640.10 1 245 1.1E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS21490 024b104e42e159f229040e19e0145a9d 395 Gene3D G3DSA:3.90.1150.10 247 392 3.4E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS21490 024b104e42e159f229040e19e0145a9d 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS21490 024b104e42e159f229040e19e0145a9d 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 376 2.0E-146 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS21490 024b104e42e159f229040e19e0145a9d 395 SUPERFAMILY SSF53383 5 377 1.48E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS21490 024b104e42e159f229040e19e0145a9d 395 PIRSF PIRSF001434 1 380 4.7E-144 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 Gene3D G3DSA:2.60.40.420 392 522 9.2E-37 T 29-03-2018 IPR008972 Cupredoxin A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 SUPERFAMILY SSF49503 66 195 3.02E-39 T 29-03-2018 IPR008972 Cupredoxin A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 Pfam PF07732 Multicopper oxidase 75 187 4.6E-39 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 Gene3D G3DSA:2.60.40.420 195 391 8.3E-36 T 29-03-2018 IPR008972 Cupredoxin A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 PRINTS PR00695 Copper containing nitrite reductase signature 64 82 3.7E-5 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 PRINTS PR00695 Copper containing nitrite reductase signature 153 168 3.7E-5 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 PRINTS PR00695 Copper containing nitrite reductase signature 90 106 3.7E-5 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 Gene3D G3DSA:2.60.40.420 25 194 1.9E-36 T 29-03-2018 IPR008972 Cupredoxin A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 SUPERFAMILY SSF49503 406 513 7.7E-36 T 29-03-2018 IPR008972 Cupredoxin A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 Pfam PF00394 Multicopper oxidase 246 341 1.3E-11 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 ProSitePatterns PS00079 Multicopper oxidases signature 1. 496 516 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 SUPERFAMILY SSF49503 191 341 8.91E-27 T 29-03-2018 IPR008972 Cupredoxin A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 Pfam PF07731 Multicopper oxidase 406 516 5.0E-28 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A616_RS14735 dff37d219838fd56c26ed0f3c45e3a8d 536 ProSitePatterns PS00080 Multicopper oxidases signature 2. 501 512 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 A616_RS23335 a392de2dcd217d59e9fb567cfa1f2251 412 SUPERFAMILY SSF53686 39 363 2.1E-58 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS23335 a392de2dcd217d59e9fb567cfa1f2251 412 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 44 378 3.0E-53 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS23335 a392de2dcd217d59e9fb567cfa1f2251 412 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 27 399 2.9E-165 T 29-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 A616_RS23335 a392de2dcd217d59e9fb567cfa1f2251 412 Gene3D G3DSA:3.40.50.1100 187 388 1.2E-25 T 29-03-2018 A616_RS23335 a392de2dcd217d59e9fb567cfa1f2251 412 Gene3D G3DSA:3.40.50.1100 6 186 2.3E-31 T 29-03-2018 A616_RS23335 a392de2dcd217d59e9fb567cfa1f2251 412 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 11 402 2.6E-175 T 29-03-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 SUPERFAMILY SSF158745 515 847 1.57E-20 T 29-03-2018 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 Gene3D G3DSA:3.30.2430.10 12 181 6.4E-35 T 29-03-2018 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 SMART SM00220 228 472 4.7E-4 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 Gene3D G3DSA:1.10.510.10 314 561 1.3E-13 T 29-03-2018 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 Pfam PF00069 Protein kinase domain 240 391 1.5E-13 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 SUPERFAMILY SSF56112 227 445 2.19E-26 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 Gene3D G3DSA:3.30.200.20 218 313 3.4E-8 T 29-03-2018 A616_RS18035 cb02633e0565486c76e5cedabd4b9880 872 SMART SM01260 522 845 8.0E-4 T 29-03-2018 IPR007822 Lanthionine synthetase C-like A616_RS03900 432bc3f62db7040b04aba3899dcbe222 231 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 8 223 1.0E-67 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A616_RS03900 432bc3f62db7040b04aba3899dcbe222 231 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.279 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A616_RS03900 432bc3f62db7040b04aba3899dcbe222 231 Gene3D G3DSA:3.20.20.390 2 224 1.3E-25 T 29-03-2018 A616_RS03900 432bc3f62db7040b04aba3899dcbe222 231 Pfam PF01884 PcrB family 3 226 2.0E-71 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A616_RS03900 432bc3f62db7040b04aba3899dcbe222 231 SUPERFAMILY SSF51395 4 222 8.79E-48 T 29-03-2018 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 SMART SM01374 1 122 6.4E-86 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.3E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.89 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 Gene3D G3DSA:2.40.150.20 1 122 2.5E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 SUPERFAMILY SSF50193 1 122 4.32E-51 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A616_RS01450 f27c04522cfb3be721604d077c7637ea 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 7.2E-55 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A616_RS18300 977c31894addc223594c18b871787731 820 PRINTS PR00775 90kDa heat shock protein signature 429 446 2.7E-9 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS18300 977c31894addc223594c18b871787731 820 PRINTS PR00775 90kDa heat shock protein signature 379 401 2.7E-9 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS18300 977c31894addc223594c18b871787731 820 PRINTS PR00775 90kDa heat shock protein signature 478 500 2.7E-9 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS18300 977c31894addc223594c18b871787731 820 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 383 501 2.1E-6 T 29-03-2018 A616_RS18300 977c31894addc223594c18b871787731 820 SUPERFAMILY SSF55874 360 576 5.24E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18300 977c31894addc223594c18b871787731 820 Gene3D G3DSA:1.10.3210.10 44 333 4.7E-12 T 29-03-2018 A616_RS18300 977c31894addc223594c18b871787731 820 Gene3D G3DSA:3.30.565.10 350 586 2.7E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18300 977c31894addc223594c18b871787731 820 SUPERFAMILY SSF109604 165 272 1.5E-5 T 29-03-2018 A616_RS18300 977c31894addc223594c18b871787731 820 SUPERFAMILY SSF109604 54 106 1.5E-5 T 29-03-2018 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Gene3D G3DSA:2.40.110.10 145 239 1.3E-33 T 29-03-2018 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 414 3.7E-36 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Gene3D G3DSA:1.20.140.10 424 592 1.7E-7 T 29-03-2018 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 SUPERFAMILY SSF47203 256 420 3.22E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Gene3D G3DSA:1.20.140.10 240 423 5.3E-53 T 29-03-2018 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 SUPERFAMILY SSF56645 21 262 4.71E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 142 2.5E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Gene3D G3DSA:1.10.540.10 2 144 3.3E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS26955 acb345869b337ffbc2143396ea82a999 592 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 239 1.9E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 211 453 1.8E-61 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 SUPERFAMILY SSF52922 476 584 1.28E-23 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 479 573 1.6E-13 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 Gene3D G3DSA:3.40.50.920 473 584 1.2E-19 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 176 1.0E-41 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 SUPERFAMILY SSF52518 198 459 2.57E-70 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 Gene3D G3DSA:3.40.50.970 196 472 7.9E-60 T 29-03-2018 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 SUPERFAMILY SSF53323 1 221 1.7E-43 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 Gene3D G3DSA:3.40.920.10 2 182 1.9E-42 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A616_RS19590 0bfd9335488857597039efed2ed6bc8e 592 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 577 1.5E-207 T 29-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 A616_RS08590 fd2fa64580e4a39e459fbfbc293d008d 61 Pfam PF06445 GyrI-like small molecule binding domain 6 59 9.2E-8 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain A616_RS08590 fd2fa64580e4a39e459fbfbc293d008d 61 Gene3D G3DSA:3.20.80.10 2 61 9.9E-12 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS08590 fd2fa64580e4a39e459fbfbc293d008d 61 SUPERFAMILY SSF55136 6 61 3.84E-9 T 29-03-2018 A616_RS26740 566cb390eb7c7eb93ffe86498d54b84e 64 Pfam PF01361 Tautomerase enzyme 2 55 3.5E-17 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A616_RS26740 566cb390eb7c7eb93ffe86498d54b84e 64 Gene3D G3DSA:3.30.429.10 1 64 9.0E-24 T 29-03-2018 A616_RS26740 566cb390eb7c7eb93ffe86498d54b84e 64 SUPERFAMILY SSF55331 2 62 1.1E-19 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily A616_RS26740 566cb390eb7c7eb93ffe86498d54b84e 64 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 62 1.5E-16 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Gene3D G3DSA:2.60.120.260 1 212 2.6E-70 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 45 212 4.1E-53 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 380 405 - T 29-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 SUPERFAMILY SSF49303 214 328 1.11E-21 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Pfam PF16353 Domain of unknown function(DUF4981) 625 715 8.7E-28 T 29-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Gene3D G3DSA:3.20.20.80 329 610 2.4E-83 T 29-03-2018 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Pfam PF02929 Beta galactosidase small chain 746 1014 5.1E-80 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Gene3D G3DSA:2.60.40.10 615 722 1.8E-31 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 SUPERFAMILY SSF74650 733 1016 2.35E-89 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 330 613 2.0E-113 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 SUPERFAMILY SSF49785 5 213 1.7E-69 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 SMART SM01038 744 1015 1.0E-123 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Pfam PF00703 Glycosyl hydrolases family 2 215 328 2.6E-15 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 SUPERFAMILY SSF49303 607 717 1.82E-29 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Gene3D G3DSA:2.60.40.10 214 328 3.4E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 Gene3D G3DSA:2.70.98.10 729 1017 2.9E-102 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 445 459 - T 29-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 140 155 1.8E-34 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 339 353 1.8E-34 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 517 532 1.8E-34 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 445 460 1.8E-34 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 370 388 1.8E-34 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A616_RS31795 46769eb1399e6c16f3b67dccccb05c11 1034 SUPERFAMILY SSF51445 330 609 1.72E-99 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS24705 dbb0a45f9531e4d60317b466818e8a92 358 SUPERFAMILY SSF53850 41 349 7.91E-71 T 29-03-2018 A616_RS24705 dbb0a45f9531e4d60317b466818e8a92 358 Pfam PF13343 Bacterial extracellular solute-binding protein 92 310 2.5E-37 T 29-03-2018 A616_RS24705 dbb0a45f9531e4d60317b466818e8a92 358 PIRSF PIRSF002825 1 352 3.6E-95 T 29-03-2018 IPR026045 Ferric binding protein A616_RS24705 dbb0a45f9531e4d60317b466818e8a92 358 Gene3D G3DSA:3.40.190.10 159 313 1.6E-35 T 29-03-2018 A616_RS24705 dbb0a45f9531e4d60317b466818e8a92 358 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 36 356 1.3E-140 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative A616_RS24705 dbb0a45f9531e4d60317b466818e8a92 358 Gene3D G3DSA:3.40.190.10 25 158 1.3E-15 T 29-03-2018 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 35 291 2.3E-85 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 Gene3D G3DSA:3.40.50.150 92 296 7.0E-47 T 29-03-2018 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 SUPERFAMILY SSF53335 13 292 9.04E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 198 204 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 Pfam PF05175 Methyltransferase small domain 125 208 4.2E-13 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 12 295 9.5E-73 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 Gene3D G3DSA:1.10.8.10 11 91 5.1E-19 T 29-03-2018 A616_RS30040 290ebe6ec325cd88a04eb4404b01ed9a 296 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 13 295 42.991 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A616_RS02610 7f8387a169b87a331cdca25837589a28 434 SUPERFAMILY SSF53383 7 424 2.76E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS02610 7f8387a169b87a331cdca25837589a28 434 PIRSF PIRSF001434 1 428 7.0E-134 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS02610 7f8387a169b87a331cdca25837589a28 434 Gene3D G3DSA:3.40.640.10 7 291 1.1E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS02610 7f8387a169b87a331cdca25837589a28 434 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 425 2.0E-149 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS02610 7f8387a169b87a331cdca25837589a28 434 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS02610 7f8387a169b87a331cdca25837589a28 434 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 425 7.8E-215 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 A616_RS02610 7f8387a169b87a331cdca25837589a28 434 Gene3D G3DSA:3.90.1150.10 293 433 5.7E-53 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29095 5a9709abfe145f1c438765a03492c197 44 Pfam PF13215 Protein of unknown function (DUF4023) 6 42 3.4E-20 T 29-03-2018 IPR025097 Protein of unknown function DUF4023 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 Gene3D G3DSA:1.10.3370.10 1 431 9.1E-158 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 Pfam PF00344 SecY translocase 67 414 2.5E-116 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 ProSitePatterns PS00755 Protein secY signature 1. 67 86 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 30.631 T 29-03-2018 IPR026593 Protein translocase subunit SecY A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 SUPERFAMILY SSF103491 2 421 5.75E-126 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 3.9E-140 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 ProSitePatterns PS00756 Protein secY signature 2. 163 180 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PIRSF PIRSF004557 1 431 7.0E-125 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 66 86 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 144 169 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 170 193 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 108 131 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 2.1E-99 T 29-03-2018 A616_RS01500 6d3995baa1f50dd684a1b4e1635179d3 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 2.1E-99 T 29-03-2018 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 Gene3D G3DSA:1.10.579.10 295 478 2.3E-75 T 29-03-2018 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 344 363 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 SUPERFAMILY SSF52425 3 168 3.79E-52 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 Gene3D G3DSA:1.25.40.80 128 294 7.1E-39 T 29-03-2018 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 Pfam PF03441 FAD binding domain of DNA photolyase 275 474 1.4E-85 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 Gene3D G3DSA:3.40.50.620 1 127 1.5E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 PRINTS PR00147 DNA photolyase signature 139 155 1.8E-30 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 PRINTS PR00147 DNA photolyase signature 344 362 1.8E-30 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 PRINTS PR00147 DNA photolyase signature 324 340 1.8E-30 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 PRINTS PR00147 DNA photolyase signature 383 397 1.8E-30 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 SUPERFAMILY SSF48173 201 478 9.55E-112 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A616_RS30060 6e2ba9edf16ec78618bde8e69fc875dd 484 Pfam PF00875 DNA photolyase 3 162 1.3E-47 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Pfam PF08447 PAS fold 181 263 4.7E-7 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Gene3D G3DSA:3.30.70.270 288 447 1.8E-63 T 29-03-2018 A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SMART SM00052 454 698 2.6E-132 T 29-03-2018 IPR001633 EAL domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SUPERFAMILY SSF55073 288 446 1.1E-51 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SUPERFAMILY SSF55785 44 143 2.62E-29 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Pfam PF00563 EAL domain 460 693 3.1E-79 T 29-03-2018 IPR001633 EAL domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Pfam PF00990 Diguanylate cyclase, GGDEF domain 283 439 2.6E-53 T 29-03-2018 IPR000160 GGDEF domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SMART SM00086 230 272 6.2E-4 T 29-03-2018 IPR001610 PAC motif A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SMART SM00086 104 146 5.0E-10 T 29-03-2018 IPR001610 PAC motif A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Pfam PF13426 PAS domain 45 144 4.0E-16 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SMART SM00267 272 444 2.7E-69 T 29-03-2018 IPR000160 GGDEF domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SUPERFAMILY SSF141868 459 705 2.22E-93 T 29-03-2018 IPR001633 EAL domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Gene3D G3DSA:3.20.20.450 448 708 1.5E-106 T 29-03-2018 IPR001633 EAL domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 40 153 4.6E-15 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 154 278 5.3E-14 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SUPERFAMILY SSF55785 143 270 4.01E-21 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Gene3D G3DSA:3.30.450.20 31 150 7.2E-31 T 29-03-2018 A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SMART SM00091 32 102 4.0 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 SMART SM00091 158 224 6.1E-5 T 29-03-2018 IPR000014 PAS domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 280 442 2.9E-45 T 29-03-2018 IPR000160 GGDEF domain A616_RS06650 7e7c9e57c38e399606a10ca70f8322cb 708 Gene3D G3DSA:3.30.450.20 151 287 3.2E-30 T 29-03-2018 A616_RS02175 0e530a1af75c750088639b5d8929a2d6 208 Pfam PF02525 Flavodoxin-like fold 3 202 7.5E-35 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS02175 0e530a1af75c750088639b5d8929a2d6 208 SUPERFAMILY SSF52218 1 203 7.58E-43 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS02175 0e530a1af75c750088639b5d8929a2d6 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 26.907 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A616_RS02175 0e530a1af75c750088639b5d8929a2d6 208 Gene3D G3DSA:3.40.50.360 3 208 4.1E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS22520 5144c39910613865da858872db8f3bde 206 Pfam PF01613 Flavin reductase like domain 22 169 2.1E-23 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 A616_RS22520 5144c39910613865da858872db8f3bde 206 SUPERFAMILY SSF50475 3 195 3.88E-49 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS22520 5144c39910613865da858872db8f3bde 206 SMART SM00903 19 173 7.1E-27 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 A616_RS22520 5144c39910613865da858872db8f3bde 206 Gene3D G3DSA:2.30.110.10 4 196 3.0E-51 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 Gene3D G3DSA:3.40.710.10 269 658 3.2E-99 T 29-03-2018 A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 Gene3D G3DSA:1.10.3810.10 61 264 2.0E-77 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 Pfam PF00905 Penicillin binding protein transpeptidase domain 344 621 4.4E-36 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 Gene3D G3DSA:2.60.40.10 659 751 9.7E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 SUPERFAMILY SSF53955 60 269 2.56E-73 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 SUPERFAMILY SSF56601 227 249 2.44E-107 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 SUPERFAMILY SSF56601 281 644 2.44E-107 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 80 626 5.4E-176 T 29-03-2018 A616_RS23695 ce59c0168b2950f155eac5feffb9051a 838 Pfam PF00912 Transglycosylase 71 245 1.5E-62 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 SMART SM00422 12 80 5.3E-29 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 4.3E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 24 4.3E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 37 4.3E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 Gene3D G3DSA:1.10.1660.10 66 137 6.0E-15 T 29-03-2018 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 Gene3D G3DSA:1.10.1660.10 7 65 3.0E-25 T 29-03-2018 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 SUPERFAMILY SSF46955 12 118 5.13E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 Pfam PF13411 MerR HTH family regulatory protein 13 78 9.6E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS09375 efe14c66aca3036e8cab7bda78326a9f 138 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 471 1.3E-164 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 460 1.0E-31 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 Gene3D G3DSA:3.50.50.60 6 161 5.7E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 333 6.2E-70 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 9.3E-34 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 9.3E-34 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 9.3E-34 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 9.3E-34 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 9.3E-34 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PIRSF PIRSF000350 2 463 4.4E-87 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 Gene3D G3DSA:3.50.50.60 162 282 1.4E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 Gene3D G3DSA:3.30.390.30 351 474 6.7E-38 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 SUPERFAMILY SSF55424 348 471 4.3E-38 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 Gene3D G3DSA:3.50.50.60 283 348 8.7E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 455 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 284 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 5.1E-69 T 29-03-2018 A616_RS15265 d45c41acf3ef466a311ebaedd7ce2564 481 SUPERFAMILY SSF51905 8 342 2.72E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07290 ebd8d28b109e9fa44ed23dd11fcb7c28 182 Gene3D G3DSA:3.40.50.300 1 182 8.3E-68 T 29-03-2018 A616_RS07290 ebd8d28b109e9fa44ed23dd11fcb7c28 182 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 6 182 7.0E-54 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A616_RS07290 ebd8d28b109e9fa44ed23dd11fcb7c28 182 SUPERFAMILY SSF52540 6 182 8.84E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS07290 ebd8d28b109e9fa44ed23dd11fcb7c28 182 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 182 1.0E-61 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A616_RS07290 ebd8d28b109e9fa44ed23dd11fcb7c28 182 PIRSF PIRSF015617 1 182 1.8E-63 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 Gene3D G3DSA:3.30.70.260 1 88 5.4E-28 T 29-03-2018 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 8.0E-20 T 29-03-2018 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 SUPERFAMILY SSF55021 1 76 8.99E-24 T 29-03-2018 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 Pfam PF13710 ACT domain 12 74 3.4E-17 T 29-03-2018 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 1.4E-59 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 Gene3D G3DSA:3.30.70.1150 89 160 2.2E-27 T 29-03-2018 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 Pfam PF10369 Small subunit of acetolactate synthase 85 157 6.8E-27 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A616_RS09480 97497d83f2e5b6668ae034affea4e756 168 SUPERFAMILY SSF55021 80 158 1.53E-23 T 29-03-2018 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 8.0E-17 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 2.6E-23 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.6E-23 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 2.6E-23 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.6E-23 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 Gene3D G3DSA:3.30.1360.40 74 146 1.8E-29 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 SUPERFAMILY SSF55252 80 149 3.66E-21 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 68.827 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 Gene3D G3DSA:1.10.10.10 3 66 3.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 8.6E-52 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 146 3.5E-27 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 SUPERFAMILY SSF46785 3 78 1.17E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13165 02069a95311534bddf1d605a68fb8c27 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 1.1E-28 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 SUPERFAMILY SSF57716 220 267 8.84E-12 T 29-03-2018 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 110 3.4E-20 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 SMART SM00898 2 115 6.0E-26 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 Pfam PF06827 Zinc finger found in FPG and IleRS 240 268 1.1E-6 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 Gene3D G3DSA:1.10.8.50 123 268 1.9E-40 T 29-03-2018 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 Gene3D G3DSA:3.20.190.10 2 122 4.8E-26 T 29-03-2018 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 SMART SM01232 129 221 5.7E-31 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 SUPERFAMILY SSF46946 129 214 3.14E-24 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 SUPERFAMILY SSF81624 2 138 9.29E-29 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A616_RS30345 44b2f08b5215df7b9fa3d9b750b5f110 268 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 213 3.5E-20 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A616_RS21455 02763ee517c51e43bc627822dcf7b76e 215 SMART SM00849 17 194 1.8E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS21455 02763ee517c51e43bc627822dcf7b76e 215 Pfam PF00753 Metallo-beta-lactamase superfamily 14 194 3.1E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS21455 02763ee517c51e43bc627822dcf7b76e 215 Gene3D G3DSA:3.60.15.10 4 214 4.8E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS21455 02763ee517c51e43bc627822dcf7b76e 215 SUPERFAMILY SSF56281 17 211 4.59E-55 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 SUPERFAMILY SSF49785 541 650 1.96E-27 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 Gene3D G3DSA:2.60.120.380 672 767 2.2E-6 T 29-03-2018 A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 Pfam PF00082 Subtilase family 237 524 5.0E-48 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 Gene3D G3DSA:3.40.50.200 218 533 2.6E-70 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 SUPERFAMILY SSF52743 224 532 1.44E-65 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 PRINTS PR00723 Subtilisin serine protease family (S8) signature 470 486 6.6E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 PRINTS PR00723 Subtilisin serine protease family (S8) signature 237 256 6.6E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 PRINTS PR00723 Subtilisin serine protease family (S8) signature 279 292 6.6E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 Gene3D G3DSA:2.60.120.380 535 652 1.6E-32 T 29-03-2018 A616_RS18780 a2812d798a1ed4d62166b52547b93f48 768 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 283 293 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 4.0E-28 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 PIRSF PIRSF016578 3 98 6.5E-4 T 29-03-2018 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 PIRSF PIRSF016578 110 377 9.2E-11 T 29-03-2018 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 Gene3D G3DSA:1.20.140.10 218 382 2.3E-58 T 29-03-2018 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 4.1E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 5.5E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 SUPERFAMILY SSF56645 3 242 6.02E-81 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 SUPERFAMILY SSF47203 228 380 3.87E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 Gene3D G3DSA:1.10.540.10 1 120 2.2E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15740 6adc8d2285f8ce37ff9dc97ac072a60b 382 Gene3D G3DSA:2.40.110.10 121 217 8.1E-40 T 29-03-2018 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 620 724 3.9E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Pfam PF08448 PAS fold 383 488 6.9E-6 T 29-03-2018 IPR013656 PAS fold-4 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 683 5.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 686 704 5.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 655 669 5.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 710 723 5.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Gene3D G3DSA:1.10.287.130 494 570 1.4E-10 T 29-03-2018 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Gene3D G3DSA:3.30.565.10 577 728 2.2E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SUPERFAMILY SSF47384 494 570 1.18E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Pfam PF00672 HAMP domain 318 362 5.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SMART SM00387 617 726 8.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Gene3D G3DSA:3.30.450.20 355 493 6.4E-14 T 29-03-2018 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SUPERFAMILY SSF55785 366 484 2.51E-7 T 29-03-2018 IPR000014 PAS domain A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SMART SM00388 501 575 0.0012 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SUPERFAMILY SSF55874 566 724 7.99E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Gene3D G3DSA:3.30.450.20 155 293 7.8E-4 T 29-03-2018 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SUPERFAMILY SSF158472 320 362 5.75E-9 T 29-03-2018 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 Pfam PF00512 His Kinase A (phospho-acceptor) domain 503 570 1.3E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS26580 66e27ca2168d4c0ff3b63998c811714d 728 SMART SM00304 314 366 3.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS31970 b71da19b2f4e2127e312629d45bdcba7 499 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 491 54.266 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 A616_RS31970 b71da19b2f4e2127e312629d45bdcba7 499 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 489 4.2E-220 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 A616_RS31970 b71da19b2f4e2127e312629d45bdcba7 499 SUPERFAMILY SSF51905 6 279 1.84E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS31970 b71da19b2f4e2127e312629d45bdcba7 499 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 491 1.9E-242 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 A616_RS31970 b71da19b2f4e2127e312629d45bdcba7 499 Gene3D G3DSA:3.50.50.60 2 453 1.1E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS18650 0d37a99c88832843516e389795e09673 220 Pfam PF02581 Thiamine monophosphate synthase 13 200 2.0E-63 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS18650 0d37a99c88832843516e389795e09673 220 SUPERFAMILY SSF51391 7 216 2.62E-64 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS18650 0d37a99c88832843516e389795e09673 220 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 213 4.8E-65 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS18650 0d37a99c88832843516e389795e09673 220 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 218 28.722 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS18650 0d37a99c88832843516e389795e09673 220 Gene3D G3DSA:3.20.20.70 2 218 3.3E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 SUPERFAMILY SSF46689 5 54 1.84E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 SMART SM00871 132 280 6.6E-13 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 Pfam PF14526 Integron-associated effector binding protein 161 279 1.2E-14 T 29-03-2018 IPR029441 Integron-associated effector binding protein A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 Gene3D G3DSA:1.10.10.60 58 121 5.9E-14 T 29-03-2018 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 8.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 8.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 Gene3D G3DSA:1.10.10.60 1 57 7.4E-13 T 29-03-2018 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 SUPERFAMILY SSF55136 156 279 1.71E-15 T 29-03-2018 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 Gene3D G3DSA:3.20.80.10 133 283 9.0E-23 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 Pfam PF12833 Helix-turn-helix domain 28 105 6.8E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 SUPERFAMILY SSF46689 57 109 5.82E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS27900 78738c8feca56901f3d664a1c3fdc829 283 SMART SM00342 21 104 6.2E-32 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF00668 Condensation domain 1833 2167 2.8E-27 T 29-03-2018 IPR001242 Condensation domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF00668 Condensation domain 10 450 4.5E-94 T 29-03-2018 IPR001242 Condensation domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF00668 Condensation domain 1056 1480 1.6E-114 T 29-03-2018 IPR001242 Condensation domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.40.50.980 617 770 2.3E-35 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF52777 1061 1223 1.33E-40 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.10.180.10 1475 1612 4.3E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF52777 195 441 1.33E-53 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF52777 15 192 3.45E-36 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:2.30.38.10 771 857 1.8E-17 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1495 1588 4.7E-15 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 ProSitePatterns PS00012 Phosphopantetheine attachment site. 997 1012 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF52777 1777 1938 1.11E-17 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 889 2.0E-122 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:1.10.1200.10 977 1034 2.4E-23 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SMART SM00823 Phosphopantetheine attachment site 976 1042 0.0014 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.40.50.980 461 616 8.2E-43 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF52777 1967 2166 8.56E-24 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF56801 429 985 4.58E-146 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF47336 967 1039 6.94E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF00550 Phosphopantetheine attachment site 974 1038 5.0E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.30.300.30 861 976 1.4E-35 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF54593 1492 1732 2.64E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF13193 AMP-binding enzyme C-terminal domain 873 946 1.6E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Pfam PF00501 AMP-binding enzyme 471 865 1.0E-89 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.30.559.10 1035 1245 3.1E-37 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.30.559.10 4 212 2.2E-28 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.30.559.10 1754 1964 2.8E-15 T 29-03-2018 A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 Gene3D G3DSA:3.10.180.10 1639 1753 2.1E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS18535 4c2679e3d7690d37a80a11f53301a572 2171 SUPERFAMILY SSF52777 1229 1478 1.33E-54 T 29-03-2018 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 SUPERFAMILY SSF56322 562 982 3.66E-92 T 29-03-2018 IPR005801 ADC synthase GO:0009058 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 SUPERFAMILY SSF56801 4 530 2.88E-129 T 29-03-2018 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 3.5E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 558 982 5.5E-134 T 29-03-2018 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Gene3D G3DSA:3.60.120.10 542 985 6.0E-86 T 29-03-2018 IPR005801 ADC synthase GO:0009058 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 PRINTS PR00095 Anthranilate synthase component I signature 931 945 2.2E-6 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 PRINTS PR00095 Anthranilate synthase component I signature 916 930 2.2E-6 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 PRINTS PR00095 Anthranilate synthase component I signature 822 835 2.2E-6 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Gene3D G3DSA:3.40.50.980 23 190 7.6E-30 T 29-03-2018 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Gene3D G3DSA:2.30.38.10 354 429 8.4E-21 T 29-03-2018 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Gene3D G3DSA:3.40.50.980 191 353 4.7E-32 T 29-03-2018 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Pfam PF00501 AMP-binding enzyme 31 435 3.5E-83 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Pfam PF00425 chorismate binding enzyme 720 974 1.3E-67 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 Gene3D G3DSA:3.30.300.30 430 528 1.7E-19 T 29-03-2018 A616_RS24440 1e9ba94f1a062eb55be1194133ce4c1c 986 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 SUPERFAMILY SSF143865 13 242 3.92E-52 T 29-03-2018 A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 Gene3D G3DSA:1.20.58.340 126 243 5.3E-28 T 29-03-2018 A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 Gene3D G3DSA:3.30.460.20 1 124 1.7E-19 T 29-03-2018 A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 16 311 4.1E-73 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 Pfam PF01544 CorA-like Mg2+ transporter protein 27 307 4.8E-69 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 Gene3D G3DSA:1.20.58.340 244 311 1.2E-21 T 29-03-2018 A616_RS26620 627c12ca8eb75b5e30bc3c90e06dcbb0 311 SUPERFAMILY SSF144083 247 308 2.35E-21 T 29-03-2018 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Pfam PF13426 PAS domain 327 401 2.3E-4 T 29-03-2018 IPR000014 PAS domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Pfam PF00989 PAS fold 416 523 1.1E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 411 535 4.6E-13 T 29-03-2018 IPR000014 PAS domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 327 408 1.3E-6 T 29-03-2018 IPR000014 PAS domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Pfam PF00512 His Kinase A (phospho-acceptor) domain 545 601 3.7E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SUPERFAMILY SSF55785 399 522 2.09E-18 T 29-03-2018 IPR000014 PAS domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SUPERFAMILY SSF141868 17 263 1.83E-80 T 29-03-2018 IPR001633 EAL domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SUPERFAMILY SSF55874 602 752 1.26E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Pfam PF00563 EAL domain 17 251 1.2E-67 T 29-03-2018 IPR001633 EAL domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 PRINTS PR00344 Bacterial sensor protein C-terminal signature 702 712 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 PRINTS PR00344 Bacterial sensor protein C-terminal signature 713 731 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 PRINTS PR00344 Bacterial sensor protein C-terminal signature 684 698 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 PRINTS PR00344 Bacterial sensor protein C-terminal signature 737 750 1.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SUPERFAMILY SSF55785 321 405 1.2E-7 T 29-03-2018 IPR000014 PAS domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Gene3D G3DSA:3.30.450.20 295 406 4.3E-9 T 29-03-2018 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Gene3D G3DSA:3.20.20.450 4 270 1.6E-88 T 29-03-2018 IPR001633 EAL domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Gene3D G3DSA:1.10.287.130 535 601 2.1E-11 T 29-03-2018 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SMART SM00388 543 605 1.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Gene3D G3DSA:3.30.565.10 606 758 2.2E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SUPERFAMILY SSF47384 539 601 4.32E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Gene3D G3DSA:3.30.450.20 407 534 3.1E-20 T 29-03-2018 A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SMART SM00052 11 256 4.7E-96 T 29-03-2018 IPR001633 EAL domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SMART SM00091 414 480 1.1E-7 T 29-03-2018 IPR000014 PAS domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 SMART SM00387 646 753 3.0E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14610 5bffaf395760581ec0668bd51cf0d02c 760 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 647 752 2.4E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23455 7c5731c2894f6c1ec30f83723efbadaa 512 Pfam PF12708 Pectate lyase superfamily protein 2 94 6.9E-15 T 29-03-2018 IPR024535 Pectate lyase superfamily protein A616_RS23455 7c5731c2894f6c1ec30f83723efbadaa 512 SUPERFAMILY SSF51126 283 391 1.76E-22 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor A616_RS23455 7c5731c2894f6c1ec30f83723efbadaa 512 SUPERFAMILY SSF51126 1 158 1.76E-22 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor A616_RS23455 7c5731c2894f6c1ec30f83723efbadaa 512 Gene3D G3DSA:2.160.20.10 1 495 6.2E-30 T 29-03-2018 IPR012334 Pectin lyase fold A616_RS19695 7eca3ada30d22e0d973454d1320fef44 348 Gene3D G3DSA:3.40.50.2300 163 348 6.6E-46 T 29-03-2018 A616_RS19695 7eca3ada30d22e0d973454d1320fef44 348 Gene3D G3DSA:3.40.50.2300 44 162 3.8E-43 T 29-03-2018 A616_RS19695 7eca3ada30d22e0d973454d1320fef44 348 SUPERFAMILY SSF53822 58 270 2.05E-11 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS19695 7eca3ada30d22e0d973454d1320fef44 348 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 46 347 2.6E-79 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 306 388 1.1E-6 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 Gene3D G3DSA:3.90.190.20 308 450 3.9E-21 T 29-03-2018 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 SUPERFAMILY SSF53623 8 306 9.04E-94 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 Pfam PF08245 Mur ligase middle domain 51 279 1.4E-13 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 49 72 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 SUPERFAMILY SSF53244 308 450 1.39E-22 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 Gene3D G3DSA:3.40.1190.10 8 307 2.7E-85 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 TIGRFAM TIGR01499 folC: bifunctional protein FolC 29 447 2.8E-126 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A616_RS10450 e511977103ee8facca6c45b6d2958c1b 457 PIRSF PIRSF001563 2 454 4.3E-145 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A616_RS30410 410d9aea550c59a7b6504bf806d9118c 282 Gene3D G3DSA:3.40.50.1820 7 281 1.3E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS30410 410d9aea550c59a7b6504bf806d9118c 282 Pfam PF12697 Alpha/beta hydrolase family 32 274 4.7E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS30410 410d9aea550c59a7b6504bf806d9118c 282 SUPERFAMILY SSF53474 9 281 9.06E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS30410 410d9aea550c59a7b6504bf806d9118c 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 6.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS30410 410d9aea550c59a7b6504bf806d9118c 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 6.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS22960 f5ae5f55a77134008bb84815dc2cc295 210 Gene3D G3DSA:3.40.630.30 1 210 8.9E-45 T 29-03-2018 A616_RS22960 f5ae5f55a77134008bb84815dc2cc295 210 SUPERFAMILY SSF55729 46 118 3.15E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS22960 f5ae5f55a77134008bb84815dc2cc295 210 PIRSF PIRSF021278 2 210 1.1E-84 T 29-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 238 255 1.1E-42 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 218 236 1.1E-42 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 20 42 1.1E-42 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 312 333 1.1E-42 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 282 297 1.1E-42 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 SUPERFAMILY SSF160544 254 361 4.19E-41 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 Gene3D G3DSA:3.40.1690.10 228 363 4.6E-56 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 Pfam PF01312 FlhB HrpN YscU SpaS Family 17 357 9.7E-131 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS19950 ea4d7c0dcb24d3570330ac37794bfb9e 365 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 18 363 2.3E-132 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 A616_RS19895 4af85c9ceff89abdbf90de01b34cfd47 472 Pfam PF03961 Flagellar Assembly Protein A 10 466 9.6E-118 T 29-03-2018 IPR005646 Flagellar assembly protein A A616_RS19895 4af85c9ceff89abdbf90de01b34cfd47 472 Gene3D G3DSA:2.40.50.100 116 199 8.7E-5 T 29-03-2018 A616_RS19895 4af85c9ceff89abdbf90de01b34cfd47 472 Gene3D G3DSA:2.160.20.70 207 409 7.5E-10 T 29-03-2018 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 2.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 2.7E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 Gene3D G3DSA:3.30.565.10 307 452 1.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 Gene3D G3DSA:1.10.287.130 224 296 2.2E-14 T 29-03-2018 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 SUPERFAMILY SSF47384 220 299 9.02E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 SUPERFAMILY SSF55874 290 451 2.62E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 448 2.0E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 SMART SM00387 346 450 6.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00170 ed9b0f61ec6989150ad6788f975a0d57 454 SMART SM00388 234 300 7.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-11 T 29-03-2018 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.2E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.6E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.6E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.6E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 Gene3D G3DSA:1.10.1900.20 55 116 2.5E-28 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 Pfam PF00453 Ribosomal protein L20 3 109 4.1E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.926 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS09440 ebb407984e7227642b796ad63f64f319 119 SUPERFAMILY SSF74731 2 116 3.4E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS31105 8595931a4b4bc21a189771b218087163 494 Gene3D G3DSA:2.10.10.20 402 450 1.5E-13 T 29-03-2018 A616_RS31105 8595931a4b4bc21a189771b218087163 494 SUPERFAMILY SSF81296 41 204 7.42E-56 T 29-03-2018 IPR014756 Immunoglobulin E-set A616_RS31105 8595931a4b4bc21a189771b218087163 494 SUPERFAMILY SSF51055 405 449 3.66E-13 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS31105 8595931a4b4bc21a189771b218087163 494 SUPERFAMILY SSF49265 214 398 7.88E-25 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS31105 8595931a4b4bc21a189771b218087163 494 Gene3D G3DSA:2.10.10.20 452 493 8.9E-15 T 29-03-2018 A616_RS31105 8595931a4b4bc21a189771b218087163 494 Gene3D G3DSA:2.60.40.10 298 392 6.8E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS31105 8595931a4b4bc21a189771b218087163 494 Gene3D G3DSA:2.60.40.10 211 297 1.4E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS31105 8595931a4b4bc21a189771b218087163 494 SMART SM00495 451 493 2.9E-13 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS31105 8595931a4b4bc21a189771b218087163 494 SMART SM00495 405 447 9.0E-12 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS31105 8595931a4b4bc21a189771b218087163 494 SUPERFAMILY SSF51055 451 493 3.4E-13 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS31105 8595931a4b4bc21a189771b218087163 494 Gene3D G3DSA:2.70.50.50 41 205 2.1E-51 T 29-03-2018 A616_RS31105 8595931a4b4bc21a189771b218087163 494 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 202 2.4E-37 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal A616_RS31105 8595931a4b4bc21a189771b218087163 494 SMART SM00060 215 288 1.1E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS31105 8595931a4b4bc21a189771b218087163 494 SMART SM00060 310 383 5.0E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 Gene3D G3DSA:3.30.450.40 91 245 6.2E-41 T 29-03-2018 IPR029016 GAF domain-like A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 Gene3D G3DSA:1.10.10.10 1 90 2.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 SUPERFAMILY SSF46785 2 78 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 Pfam PF09339 IclR helix-turn-helix domain 4 56 4.1E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 Pfam PF01614 Bacterial transcriptional regulator 123 240 1.8E-25 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 SUPERFAMILY SSF55781 70 243 2.16E-40 T 29-03-2018 IPR029016 GAF domain-like A616_RS30605 21a4629e7eeb5870d94b6ea13739ef84 246 SMART SM00346 2 94 2.1E-19 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS15270 7543ca6f30e1cc158a73a7b6183d01e1 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 114 2.0E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS15270 7543ca6f30e1cc158a73a7b6183d01e1 116 SUPERFAMILY SSF54593 1 115 2.48E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15270 7543ca6f30e1cc158a73a7b6183d01e1 116 Gene3D G3DSA:3.10.180.10 1 116 2.5E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 SMART SM00493 3 103 3.2E-33 T 29-03-2018 IPR006171 TOPRIM domain A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 633 55.359 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 3.1E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 3.1E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 3.1E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 3.1E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 294 303 3.1E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Pfam PF01131 DNA topoisomerase 128 548 3.0E-133 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:3.30.65.10 614 654 5.5E-9 T 29-03-2018 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:3.30.65.10 565 613 6.5E-17 T 29-03-2018 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:2.70.20.10 327 451 4.6E-42 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 SUPERFAMILY SSF56712 4 589 7.72E-202 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:3.40.50.140 2 129 6.9E-39 T 29-03-2018 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 SMART SM00437 242 510 3.6E-123 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Pfam PF01751 Toprim domain 4 113 4.2E-30 T 29-03-2018 IPR006171 TOPRIM domain A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 SMART SM00436 104 192 4.1E-52 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:1.10.460.10 135 326 6.2E-50 T 29-03-2018 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:1.10.460.10 452 564 6.5E-24 T 29-03-2018 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 616 655 2.3E-13 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 688 0.072 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 613 2.8E-13 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 2.0E-254 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 SUPERFAMILY SSF57783 573 613 1.36E-13 T 29-03-2018 A616_RS20085 b39b5d9cc5b4ba699f036b318e213673 692 Gene3D G3DSA:2.20.25.10 657 692 2.0E-5 T 29-03-2018 A616_RS00790 97f881aa761766f1264321273b854ed2 476 SUPERFAMILY SSF52402 9 239 1.06E-57 T 29-03-2018 A616_RS00790 97f881aa761766f1264321273b854ed2 476 SUPERFAMILY SSF82829 222 326 7.06E-10 T 29-03-2018 A616_RS00790 97f881aa761766f1264321273b854ed2 476 Gene3D G3DSA:3.50.40.10 377 463 1.4E-8 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS00790 97f881aa761766f1264321273b854ed2 476 Pfam PF09179 TilS substrate binding domain 264 327 9.8E-5 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A616_RS00790 97f881aa761766f1264321273b854ed2 476 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 212 4.5E-53 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A616_RS00790 97f881aa761766f1264321273b854ed2 476 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 390 437 4.8E-14 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A616_RS00790 97f881aa761766f1264321273b854ed2 476 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 2 321 24.397 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A616_RS00790 97f881aa761766f1264321273b854ed2 476 SUPERFAMILY SSF56037 376 461 1.99E-17 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS00790 97f881aa761766f1264321273b854ed2 476 Pfam PF11734 TilS substrate C-terminal domain 392 447 4.0E-12 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A616_RS00790 97f881aa761766f1264321273b854ed2 476 Gene3D G3DSA:3.40.50.620 15 236 1.3E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS00790 97f881aa761766f1264321273b854ed2 476 SMART SM00977 390 463 7.8E-20 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A616_RS00790 97f881aa761766f1264321273b854ed2 476 Pfam PF01171 PP-loop family 21 207 1.2E-50 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 1.5E-42 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 SUPERFAMILY SSF53738 160 258 1.57E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Gene3D G3DSA:3.30.310.50 376 448 3.8E-23 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 2.0E-185 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 SUPERFAMILY SSF55957 359 446 1.09E-26 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 255 2.5E-17 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Gene3D G3DSA:3.40.120.10 158 264 2.2E-26 T 29-03-2018 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 SUPERFAMILY SSF53738 3 182 1.57E-47 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 443 1.4E-17 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Gene3D G3DSA:3.40.120.10 265 375 4.3E-32 T 29-03-2018 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 1.6E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 1.6E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.6E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 SUPERFAMILY SSF53738 259 365 7.06E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Gene3D G3DSA:3.40.120.10 1 154 1.2E-44 T 29-03-2018 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 45.501 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01715 9bce07c7eba0ab46dbb6f78c9b666d30 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 370 3.7E-33 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 Pfam PF02321 Outer membrane efflux protein 133 233 1.8E-6 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 Pfam PF02321 Outer membrane efflux protein 299 401 1.7E-13 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 Gene3D G3DSA:1.20.1600.10 296 402 1.5E-17 T 29-03-2018 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 Gene3D G3DSA:1.20.1600.10 21 106 0.017 T 29-03-2018 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 Gene3D G3DSA:1.20.1600.10 116 294 4.7E-22 T 29-03-2018 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 SUPERFAMILY SSF56954 10 42 6.41E-48 T 29-03-2018 A616_RS29750 f4ca3e19bcf582ec0e12f5fab076fafd 402 SUPERFAMILY SSF56954 65 401 6.41E-48 T 29-03-2018 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 SMART SM00984 311 412 1.7E-39 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 288 2.4E-35 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 Gene3D G3DSA:3.40.50.720 1 195 7.4E-49 T 29-03-2018 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 4.3E-55 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 SUPERFAMILY SSF51735 1 189 2.26E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 Gene3D G3DSA:1.20.5.100 197 218 7.7E-14 T 29-03-2018 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 PIRSF PIRSF000124 1 427 1.4E-131 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 SUPERFAMILY SSF48179 197 290 2.04E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 PIRSF PIRSF500134 1 428 8.1E-152 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 311 410 2.9E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 Gene3D G3DSA:3.40.50.720 219 424 1.8E-69 T 29-03-2018 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 SUPERFAMILY SSF52413 303 422 5.89E-33 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS14055 f2b331ed925ffc039d61b36a14fd9c2b 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 408 1.8E-127 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 Pfam PF12833 Helix-turn-helix domain 197 275 4.1E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 SUPERFAMILY SSF46689 227 277 8.06E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 Gene3D G3DSA:1.10.10.60 244 282 6.6E-13 T 29-03-2018 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 Gene3D G3DSA:3.90.1240.10 108 243 2.7E-25 T 29-03-2018 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 Gene3D G3DSA:2.60.120.10 15 92 2.8E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 SUPERFAMILY SSF51215 48 162 3.14E-10 T 29-03-2018 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 258 3.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 274 3.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 SMART SM00342 191 274 7.0E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 Pfam PF02311 AraC-like ligand binding domain 49 155 2.5E-6 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A616_RS25915 297ad7f5328dec57729d66ef66e5d325 283 SUPERFAMILY SSF46689 177 224 7.17E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 254 277 7.9E-6 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 142 156 7.9E-6 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 278 292 7.9E-6 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 Gene3D G3DSA:2.40.10.10 202 292 5.8E-10 T 29-03-2018 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 144 149 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 Gene3D G3DSA:2.40.10.10 114 201 1.1E-12 T 29-03-2018 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 Pfam PF00089 Trypsin 108 286 2.7E-10 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A616_RS22135 7d9e80b9e4bb4d44bf94e9c670210bda 309 SUPERFAMILY SSF50494 125 298 2.85E-23 T 29-03-2018 IPR009003 Peptidase S1, PA clan A616_RS25830 908f13ab5e1937c4d690b941a52a8377 329 Gene3D G3DSA:2.70.70.10 146 329 2.3E-30 T 29-03-2018 A616_RS25830 908f13ab5e1937c4d690b941a52a8377 329 SUPERFAMILY SSF51261 207 301 3.09E-23 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS25830 908f13ab5e1937c4d690b941a52a8377 329 Gene3D G3DSA:3.10.450.100 41 98 5.7E-5 T 29-03-2018 A616_RS25830 908f13ab5e1937c4d690b941a52a8377 329 Pfam PF01551 Peptidase family M23 209 302 4.9E-20 T 29-03-2018 IPR016047 Peptidase M23 A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 Gene3D G3DSA:1.10.10.10 129 228 1.3E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 Pfam PF00072 Response regulator receiver domain 11 119 2.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 SUPERFAMILY SSF52172 10 179 2.57E-41 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 Gene3D G3DSA:3.40.50.2300 6 128 1.5E-32 T 29-03-2018 A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 SMART SM00862 151 226 9.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 3.5E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS15770 c99b91cf6453212e8695d4d9686d8ce1 228 SMART SM00448 8 118 1.3E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Gene3D G3DSA:3.40.120.10 384 521 8.5E-15 T 29-03-2018 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Gene3D G3DSA:3.30.310.50 709 798 0.0015 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Gene3D G3DSA:3.90.550.10 1 246 1.3E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 382 512 8.6E-17 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Pfam PF00483 Nucleotidyl transferase 2 231 1.7E-51 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 249 282 1.2E-4 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 319 352 5.0E-4 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS21070 20524ab6b092fd771e263925a43ba851 801 SUPERFAMILY SSF53738 380 515 1.02E-16 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 SUPERFAMILY SSF55957 706 789 2.04E-9 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 SUPERFAMILY SSF53448 1 235 1.71E-77 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS21070 20524ab6b092fd771e263925a43ba851 801 SUPERFAMILY SSF53448 333 344 1.71E-77 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS21070 20524ab6b092fd771e263925a43ba851 801 Gene3D G3DSA:2.160.10.10 247 383 3.8E-23 T 29-03-2018 A616_RS21070 20524ab6b092fd771e263925a43ba851 801 SUPERFAMILY SSF51161 245 419 7.9E-32 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS21020 1559ebe9e4e7f8945dca02622d28f7a5 452 Pfam PF00860 Permease family 18 399 1.2E-92 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS21020 1559ebe9e4e7f8945dca02622d28f7a5 452 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 432 3.7E-108 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A616_RS21020 1559ebe9e4e7f8945dca02622d28f7a5 452 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.939 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:1.20.5.340 745 866 0.34 T 29-03-2018 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:1.20.5.170 664 744 0.26 T 29-03-2018 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Pfam PF06470 SMC proteins Flexible Hinge Domain 518 638 3.3E-33 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 PIRSF PIRSF005719 1 1187 0.0 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 4.2E-67 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:1.10.287.620 173 323 0.0031 T 29-03-2018 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:1.20.120.330 420 540 0.05 T 29-03-2018 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 SUPERFAMILY SSF75553 480 687 7.45E-55 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 SUPERFAMILY SSF52540 1 219 1.91E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 SUPERFAMILY SSF52540 1078 1165 1.91E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:1.20.5.50 324 419 0.0085 T 29-03-2018 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 SMART SM00968 519 638 5.7E-43 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:3.40.50.300 954 1184 3.7E-34 T 29-03-2018 A616_RS20265 19d6b162412359d0ceea7759d96c7bcb 1190 Gene3D G3DSA:3.40.50.300 1 172 7.8E-42 T 29-03-2018 A616_RS02425 bb12d3bcecee2bf12cf6bf66bd7ad1d6 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS02425 bb12d3bcecee2bf12cf6bf66bd7ad1d6 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.7E-19 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS02425 bb12d3bcecee2bf12cf6bf66bd7ad1d6 49 Pfam PF00471 Ribosomal protein L33 3 49 3.2E-22 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS02425 bb12d3bcecee2bf12cf6bf66bd7ad1d6 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.382 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS02425 bb12d3bcecee2bf12cf6bf66bd7ad1d6 49 SUPERFAMILY SSF57829 1 49 2.69E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A616_RS14140 39eef3c4eda1ea8d045c5c451abac0c6 372 Pfam PF14398 YheC/D like ATP-grasp 99 352 2.0E-85 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS14140 39eef3c4eda1ea8d045c5c451abac0c6 372 SUPERFAMILY SSF56059 124 336 5.82E-12 T 29-03-2018 A616_RS14140 39eef3c4eda1ea8d045c5c451abac0c6 372 Gene3D G3DSA:3.30.470.20 101 345 3.2E-16 T 29-03-2018 A616_RS06880 246df378c755d635b60c5044d589d71e 390 Gene3D G3DSA:1.10.10.10 3 81 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06880 246df378c755d635b60c5044d589d71e 390 Gene3D G3DSA:3.40.50.150 104 332 7.0E-19 T 29-03-2018 A616_RS06880 246df378c755d635b60c5044d589d71e 390 Pfam PF01861 Protein of unknown function DUF43 111 308 1.9E-41 T 29-03-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A616_RS06880 246df378c755d635b60c5044d589d71e 390 SUPERFAMILY SSF53335 171 249 4.5E-6 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Gene3D G3DSA:3.40.1130.10 5 207 1.1E-27 T 29-03-2018 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Gene3D G3DSA:2.30.38.10 527 598 3.0E-13 T 29-03-2018 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 SMART SM00563 32 140 1.1E-23 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 ProSitePatterns PS00455 Putative AMP-binding domain signature. 368 379 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 SUPERFAMILY SSF56801 231 699 4.19E-89 T 29-03-2018 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Pfam PF00501 AMP-binding enzyme 257 605 1.8E-59 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 SUPERFAMILY SSF69593 5 195 1.57E-27 T 29-03-2018 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Gene3D G3DSA:3.40.50.980 372 526 3.1E-38 T 29-03-2018 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Pfam PF01553 Acyltransferase 19 137 1.1E-15 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Gene3D G3DSA:3.30.300.30 603 701 1.7E-10 T 29-03-2018 A616_RS31035 1464208c0ac9c933580509dbed2b6ed0 702 Gene3D G3DSA:3.40.50.980 208 371 1.2E-15 T 29-03-2018 A616_RS07200 545962ef5ad1b864cd3ac9917ca6f0fd 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 212 3.7E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07200 545962ef5ad1b864cd3ac9917ca6f0fd 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 2.7E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS07200 545962ef5ad1b864cd3ac9917ca6f0fd 216 SUPERFAMILY SSF161098 15 201 1.57E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07200 545962ef5ad1b864cd3ac9917ca6f0fd 216 Gene3D G3DSA:1.10.3720.10 8 215 3.1E-46 T 29-03-2018 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.959 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 Pfam PF00164 Ribosomal protein S12/S23 31 136 5.2E-38 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 Gene3D G3DSA:2.40.50.140 1 146 4.7E-64 T 29-03-2018 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 9.2E-69 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01360 b0444d53ca1df0980f3bb9469bbe0e9c 147 SUPERFAMILY SSF50249 2 136 4.11E-48 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 Gene3D G3DSA:3.40.50.2300 2 126 2.3E-31 T 29-03-2018 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 SUPERFAMILY SSF52172 3 130 8.11E-32 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 Gene3D G3DSA:1.10.10.10 127 231 1.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 9.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 9.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 9.1E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 SMART SM00421 167 224 7.2E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 184 211 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 SUPERFAMILY SSF46894 168 225 8.84E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 170 223 3.5E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 SMART SM00448 3 115 7.1E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04385 7d6584e0a3f2e23b93e9abd7e8dc790e 233 Pfam PF00072 Response regulator receiver domain 5 116 6.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30185 893165b3a2d333636540f75c2946c601 691 SUPERFAMILY SSF103501 8 239 8.76E-14 T 29-03-2018 IPR023234 NarG-like domain A616_RS30185 893165b3a2d333636540f75c2946c601 691 SUPERFAMILY SSF46548 353 400 8.89E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS30185 893165b3a2d333636540f75c2946c601 691 SUPERFAMILY SSF46548 254 313 8.89E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS30185 893165b3a2d333636540f75c2946c601 691 Gene3D G3DSA:1.20.950.20 2 237 2.0E-39 T 29-03-2018 A616_RS30185 893165b3a2d333636540f75c2946c601 691 Gene3D G3DSA:1.10.1060.10 244 404 1.7E-34 T 29-03-2018 A616_RS30185 893165b3a2d333636540f75c2946c601 691 Pfam PF02754 Cysteine-rich domain 465 539 9.2E-7 T 29-03-2018 IPR004017 Cysteine-rich domain A616_RS30185 893165b3a2d333636540f75c2946c601 691 Pfam PF02754 Cysteine-rich domain 578 665 1.1E-16 T 29-03-2018 IPR004017 Cysteine-rich domain A616_RS30185 893165b3a2d333636540f75c2946c601 691 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 277 288 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS30185 893165b3a2d333636540f75c2946c601 691 Pfam PF13183 4Fe-4S dicluster domain 274 383 3.0E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS30185 893165b3a2d333636540f75c2946c601 691 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS14650 4e26b4f2d09b268253eeaa8e70f6eda8 526 PIRSF PIRSF002741 4 523 5.4E-119 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS14650 4e26b4f2d09b268253eeaa8e70f6eda8 526 SUPERFAMILY SSF53850 44 525 2.9E-137 T 29-03-2018 A616_RS14650 4e26b4f2d09b268253eeaa8e70f6eda8 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 448 1.0E-98 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS14650 4e26b4f2d09b268253eeaa8e70f6eda8 526 Gene3D G3DSA:3.40.190.10 167 302 1.7E-43 T 29-03-2018 A616_RS14650 4e26b4f2d09b268253eeaa8e70f6eda8 526 Gene3D G3DSA:3.10.105.10 303 498 3.8E-49 T 29-03-2018 A616_RS14650 4e26b4f2d09b268253eeaa8e70f6eda8 526 Gene3D G3DSA:3.90.76.10 70 166 3.3E-26 T 29-03-2018 A616_RS27380 4708277aae29046fb3c3033479dc0112 413 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 295 386 1.4E-8 T 29-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain A616_RS27380 4708277aae29046fb3c3033479dc0112 413 SUPERFAMILY SSF56300 1 349 1.78E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS27380 4708277aae29046fb3c3033479dc0112 413 Gene3D G3DSA:3.60.21.10 1 74 1.3E-14 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS27380 4708277aae29046fb3c3033479dc0112 413 Gene3D G3DSA:3.60.21.10 75 295 4.4E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS27380 4708277aae29046fb3c3033479dc0112 413 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 119 2.4E-38 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 A616_RS27380 4708277aae29046fb3c3033479dc0112 413 Pfam PF00149 Calcineurin-like phosphoesterase 1 243 6.4E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS03580 dc4c058ac1276ba7acb0e7d9a56b14dd 311 SUPERFAMILY SSF144083 247 309 8.5E-13 T 29-03-2018 A616_RS03580 dc4c058ac1276ba7acb0e7d9a56b14dd 311 Gene3D G3DSA:1.20.58.340 245 311 2.4E-12 T 29-03-2018 A616_RS03580 dc4c058ac1276ba7acb0e7d9a56b14dd 311 Gene3D G3DSA:3.30.460.20 2 132 9.1E-16 T 29-03-2018 A616_RS03580 dc4c058ac1276ba7acb0e7d9a56b14dd 311 Pfam PF01544 CorA-like Mg2+ transporter protein 22 306 1.9E-57 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A616_RS03580 dc4c058ac1276ba7acb0e7d9a56b14dd 311 Gene3D G3DSA:1.20.58.340 133 244 1.9E-11 T 29-03-2018 A616_RS03580 dc4c058ac1276ba7acb0e7d9a56b14dd 311 SUPERFAMILY SSF143865 12 246 7.19E-43 T 29-03-2018 A616_RS01755 714198e52c4d06c42f4565a896b11235 228 SUPERFAMILY SSF52172 1 167 3.13E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS01755 714198e52c4d06c42f4565a896b11235 228 Pfam PF00072 Response regulator receiver domain 3 111 9.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS01755 714198e52c4d06c42f4565a896b11235 228 Gene3D G3DSA:1.10.10.10 121 228 2.2E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01755 714198e52c4d06c42f4565a896b11235 228 SMART SM00448 1 111 9.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS01755 714198e52c4d06c42f4565a896b11235 228 SMART SM00862 146 223 6.4E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS01755 714198e52c4d06c42f4565a896b11235 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 3.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS01755 714198e52c4d06c42f4565a896b11235 228 Gene3D G3DSA:3.40.50.2300 1 120 6.5E-33 T 29-03-2018 A616_RS11225 25afacb3d5e328ba6003e05e0117cbd9 197 SUPERFAMILY SSF52374 6 195 8.59E-55 T 29-03-2018 A616_RS11225 25afacb3d5e328ba6003e05e0117cbd9 197 Gene3D G3DSA:3.40.50.620 5 195 4.8E-56 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS11225 25afacb3d5e328ba6003e05e0117cbd9 197 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 10 193 9.9E-57 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A616_RS11225 25afacb3d5e328ba6003e05e0117cbd9 197 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 6 194 31.469 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A616_RS11225 25afacb3d5e328ba6003e05e0117cbd9 197 Pfam PF01467 Cytidylyltransferase-like 10 167 3.2E-32 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS11225 25afacb3d5e328ba6003e05e0117cbd9 197 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 71 8.8E-13 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 SUPERFAMILY SSF53807 38 326 6.38E-87 T 29-03-2018 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 Gene3D G3DSA:3.40.50.1980 206 326 4.1E-40 T 29-03-2018 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 Pfam PF01297 Zinc-uptake complex component A periplasmic 42 324 1.8E-82 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00691 Adhesin B signature 304 322 7.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00691 Adhesin B signature 83 102 7.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00691 Adhesin B signature 260 277 7.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00691 Adhesin B signature 39 60 7.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00691 Adhesin B signature 211 228 7.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00691 Adhesin B signature 64 82 7.2E-13 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 Gene3D G3DSA:3.40.50.1980 28 205 1.3E-58 T 29-03-2018 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00690 Adhesin family signature 211 232 2.7E-15 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00690 Adhesin family signature 264 282 2.7E-15 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00690 Adhesin family signature 83 100 2.7E-15 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00690 Adhesin family signature 39 57 2.7E-15 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS00840 5a7612dd12fa8eeced734b3dfa4a9250 326 PRINTS PR00690 Adhesin family signature 70 83 2.7E-15 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS00465 38f01a751c06d0e9d470ebd2a830216a 129 SUPERFAMILY SSF52821 8 123 7.73E-33 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00465 38f01a751c06d0e9d470ebd2a830216a 129 SMART SM00450 33 128 2.0E-26 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00465 38f01a751c06d0e9d470ebd2a830216a 129 Gene3D G3DSA:3.40.250.10 24 127 9.4E-31 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00465 38f01a751c06d0e9d470ebd2a830216a 129 Pfam PF00581 Rhodanese-like domain 35 123 1.5E-19 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Gene3D G3DSA:3.30.70.1430 561 661 5.0E-16 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Gene3D G3DSA:3.30.70.1430 40 140 3.4E-26 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Gene3D G3DSA:1.20.1640.10 809 1032 1.6E-41 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Pfam PF00873 AcrB/AcrD/AcrF family 3 1014 6.6E-248 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82693 560 658 1.02E-9 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Gene3D G3DSA:3.30.2090.10 179 263 8.2E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82866 799 1017 1.7E-48 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82714 183 262 2.35E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82866 287 487 6.67E-42 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 8.8E-37 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82693 265 321 1.1E-19 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82693 137 180 1.1E-19 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82693 41 133 1.62E-24 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Gene3D G3DSA:1.20.1640.10 264 490 5.6E-41 T 29-03-2018 A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 Gene3D G3DSA:3.30.2090.10 710 797 7.9E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS04500 c7ffda140e4e2d4ad2d40b58ea6396f1 1043 SUPERFAMILY SSF82714 713 794 8.89E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 SUPERFAMILY SSF50129 12 146 1.32E-29 T 29-03-2018 IPR011032 GroES-like A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 Gene3D G3DSA:3.40.50.720 164 248 7.3E-14 T 29-03-2018 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 SUPERFAMILY SSF51735 123 296 8.02E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 Pfam PF13602 Zinc-binding dehydrogenase 198 344 1.6E-21 T 29-03-2018 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 SMART SM00829 22 344 1.4E-12 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 8 347 1.2E-139 T 29-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 155 176 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 Gene3D G3DSA:3.90.180.10 249 346 0.0013 T 29-03-2018 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 Gene3D G3DSA:3.90.180.10 1 163 1.0E-37 T 29-03-2018 A616_RS32065 a99e7fd23ef2d5e0d1c55f861004587f 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 96 1.0E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS11800 5894241e424e33762ca078a1df1adfa1 284 Gene3D G3DSA:3.40.630.30 127 284 1.1E-15 T 29-03-2018 A616_RS11800 5894241e424e33762ca078a1df1adfa1 284 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 18 279 4.0E-88 T 29-03-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 A616_RS11800 5894241e424e33762ca078a1df1adfa1 284 SUPERFAMILY SSF55729 126 280 1.03E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11800 5894241e424e33762ca078a1df1adfa1 284 Gene3D G3DSA:3.40.630.30 20 101 0.32 T 29-03-2018 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 475 1.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 SMART SM00388 256 322 4.6E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 SUPERFAMILY SSF55874 311 475 3.14E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 SMART SM00304 202 255 1.4E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 SUPERFAMILY SSF47384 239 318 7.65E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 SMART SM00387 368 477 5.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 SUPERFAMILY SSF158472 204 252 1.83E-6 T 29-03-2018 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 Gene3D G3DSA:3.30.565.10 326 477 1.3E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 318 5.8E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08725 dfe66fbcdd22b218672d2818bbf33bf0 477 Gene3D G3DSA:1.10.287.130 246 317 2.2E-18 T 29-03-2018 A616_RS20945 6f593076bf99faa121b71f6a3e28e01b 206 Hamap MF_01969 Kynurenine formamidase [kynB]. 2 206 43.13 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A616_RS20945 6f593076bf99faa121b71f6a3e28e01b 206 Pfam PF04199 Putative cyclase 4 149 3.8E-20 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A616_RS20945 6f593076bf99faa121b71f6a3e28e01b 206 Gene3D G3DSA:3.50.30.50 1 205 6.0E-50 T 29-03-2018 A616_RS20945 6f593076bf99faa121b71f6a3e28e01b 206 SUPERFAMILY SSF102198 1 204 2.35E-57 T 29-03-2018 A616_RS20945 6f593076bf99faa121b71f6a3e28e01b 206 TIGRFAM TIGR03035 trp_arylform: arylformamidase 3 205 2.1E-85 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 SUPERFAMILY SSF51735 4 159 2.05E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 130 3.6E-21 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 Pfam PF00742 Homoserine dehydrogenase 138 315 6.7E-61 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 Gene3D G3DSA:3.40.50.720 2 158 3.4E-34 T 29-03-2018 A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 Gene3D G3DSA:3.30.360.10 159 299 2.3E-48 T 29-03-2018 A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 SUPERFAMILY SSF55347 138 303 8.5E-50 T 29-03-2018 A616_RS20915 30743bea9b664a0d1ee5ec68cc3f4fce 421 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 2.0E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 SUPERFAMILY SSF52540 36 315 4.22E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 SMART SM00382 37 245 1.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 Gene3D G3DSA:3.40.50.300 6 338 5.9E-81 T 29-03-2018 A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 Pfam PF00005 ABC transporter 29 187 4.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 4.4E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS09175 e49cfcbf5be10674f92fdb6695685f5d 340 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 3.2E-69 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 3.2E-69 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00145 Argininosuccinate lyase family signature 310 329 3.2E-69 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 3.2E-69 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 3.2E-69 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00145 Argininosuccinate lyase family signature 275 291 3.2E-69 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 Gene3D G3DSA:1.10.40.30 375 432 1.9E-25 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 453 43.872 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 Gene3D G3DSA:1.10.275.10 2 106 1.8E-39 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 Gene3D G3DSA:1.20.200.10 107 374 8.0E-97 T 29-03-2018 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 Pfam PF14698 Argininosuccinate lyase C-terminal 363 431 1.5E-25 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 Pfam PF00206 Lyase 6 300 4.1E-79 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 7.7E-30 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 7.7E-30 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 7.7E-30 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 7.7E-30 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 SUPERFAMILY SSF48557 3 455 1.32E-154 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS29320 3694800e789d2b443f95cc26eb91690a 481 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 455 8.2E-201 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 SUPERFAMILY SSF46785 2 86 5.35E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 SUPERFAMILY SSF53850 90 294 1.72E-45 T 29-03-2018 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 Gene3D G3DSA:1.10.10.10 1 83 8.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 Pfam PF03466 LysR substrate binding domain 88 291 5.3E-49 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 Gene3D G3DSA:3.40.190.10 87 176 4.2E-23 T 29-03-2018 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 Gene3D G3DSA:3.40.190.10 177 266 9.4E-21 T 29-03-2018 A616_RS15790 0f6134f528c62e3496644c64ba8e6714 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.6E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS08695 81f25bf55663ae5d9fa0e61e34c1bd15 276 SUPERFAMILY SSF56281 25 241 1.12E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08695 81f25bf55663ae5d9fa0e61e34c1bd15 276 Gene3D G3DSA:3.60.15.10 13 222 1.3E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08695 81f25bf55663ae5d9fa0e61e34c1bd15 276 Pfam PF00753 Metallo-beta-lactamase superfamily 31 167 5.6E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08695 81f25bf55663ae5d9fa0e61e34c1bd15 276 SMART SM00849 25 194 1.0E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS18345 00e18d5b1543142e6a63ca8ae8210e57 120 Pfam PF14272 Glycine-rich SFCGS 4 116 2.7E-60 T 29-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 A616_RS18345 00e18d5b1543142e6a63ca8ae8210e57 120 TIGRFAM TIGR03577 EF_0830: conserved hypothetical protein EF_0830/AHA_3911 4 116 6.1E-55 T 29-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 Gene3D G3DSA:1.10.1740.10 7 101 1.3E-19 T 29-03-2018 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 Gene3D G3DSA:1.10.10.10 107 157 3.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 PRINTS PR00046 Major sigma-70 factor signature 206 218 2.0E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 PRINTS PR00046 Major sigma-70 factor signature 223 238 2.0E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 PRINTS PR00046 Major sigma-70 factor signature 58 71 2.0E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 PRINTS PR00046 Major sigma-70 factor signature 238 249 2.0E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 SUPERFAMILY SSF88659 181 254 1.79E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 Pfam PF04539 Sigma-70 region 3 113 174 4.1E-13 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 1 253 1.7E-105 T 29-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 253 4.4E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 Gene3D G3DSA:1.10.10.10 165 260 1.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 SUPERFAMILY SSF88659 107 182 6.1E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 253 9.1E-82 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 Pfam PF04542 Sigma-70 region 2 34 103 4.8E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 Pfam PF04545 Sigma-70, region 4 202 251 1.9E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02915 128a5c2d793e08ee61d786f74290c5eb 262 SUPERFAMILY SSF88946 12 103 1.05E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09255 26edfd50a3bca3ed6690d6866922b191 236 SUPERFAMILY SSF56037 51 225 1.33E-37 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS09255 26edfd50a3bca3ed6690d6866922b191 236 Pfam PF03483 B3/4 domain 67 196 6.4E-25 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A616_RS09255 26edfd50a3bca3ed6690d6866922b191 236 SMART SM00873 64 217 6.4E-16 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A616_RS09255 26edfd50a3bca3ed6690d6866922b191 236 Gene3D G3DSA:3.50.40.10 65 215 3.7E-29 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.1E-84 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 SMART SM01003 4 136 1.4E-79 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 Gene3D G3DSA:3.50.50.60 179 195 0.0018 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 SMART SM01002 148 297 2.6E-89 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 SUPERFAMILY SSF51735 136 303 5.61E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 PIRSF PIRSF000183 1 371 2.5E-190 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 3.1E-47 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 Gene3D G3DSA:3.40.50.720 1 178 4.0E-44 T 29-03-2018 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 Gene3D G3DSA:3.40.50.720 196 371 2.8E-45 T 29-03-2018 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.0E-178 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 SUPERFAMILY SSF52283 305 360 3.32E-66 T 29-03-2018 A616_RS27185 5cce9ff3c05b5ff50cdf54539f2e6edd 374 SUPERFAMILY SSF52283 1 136 3.32E-66 T 29-03-2018 A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 Gene3D G3DSA:3.30.70.20 73 297 1.2E-5 T 29-03-2018 A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 Pfam PF02754 Cysteine-rich domain 319 404 3.1E-13 T 29-03-2018 IPR004017 Cysteine-rich domain A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 Pfam PF02754 Cysteine-rich domain 190 273 1.4E-17 T 29-03-2018 IPR004017 Cysteine-rich domain A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 Gene3D G3DSA:3.30.70.20 27 72 1.2E-8 T 29-03-2018 A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 Gene3D G3DSA:3.30.70.20 4 26 0.097 T 29-03-2018 A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 Pfam PF13183 4Fe-4S dicluster domain 14 83 4.4E-13 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 PIRSF PIRSF000139 3 431 6.6E-133 T 29-03-2018 A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 SUPERFAMILY SSF46548 12 96 1.52E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS08840 c4230fd1e9528946287bce4961ad4f47 431 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS03385 56a8d093a5dfae7556866c629d322c1d 228 Pfam PF16316 Domain of unknown function (DUF4956) 45 160 1.6E-10 T 29-03-2018 IPR032531 Protein of unknown function DUF4956 A616_RS09715 a57dbb6d0db6db117256088caa32acc5 255 PIRSF PIRSF000090 1 255 1.8E-80 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A616_RS09715 a57dbb6d0db6db117256088caa32acc5 255 SMART SM00893 21 209 7.0E-62 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS09715 a57dbb6d0db6db117256088caa32acc5 255 SUPERFAMILY SSF52402 1 249 1.3E-75 T 29-03-2018 A616_RS09715 a57dbb6d0db6db117256088caa32acc5 255 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 153 173 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A616_RS09715 a57dbb6d0db6db117256088caa32acc5 255 Pfam PF01012 Electron transfer flavoprotein domain 23 204 6.1E-52 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS09715 a57dbb6d0db6db117256088caa32acc5 255 Gene3D G3DSA:3.40.50.620 1 255 1.1E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS02285 c39b2f3b5ac60429faf3df7075bf8487 187 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 185 35.076 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A616_RS02285 c39b2f3b5ac60429faf3df7075bf8487 187 Pfam PF02669 K+-transporting ATPase, c chain 3 183 1.1E-77 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A616_RS02285 c39b2f3b5ac60429faf3df7075bf8487 187 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 3 185 1.7E-62 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A616_RS02285 c39b2f3b5ac60429faf3df7075bf8487 187 PIRSF PIRSF001296 1 187 2.3E-79 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Gene3D G3DSA:1.10.10.10 582 639 0.0033 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 423 438 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Pfam PF00158 Sigma-54 interaction domain 337 504 3.9E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Gene3D G3DSA:1.10.10.10 640 674 0.0074 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Gene3D G3DSA:1.10.8.60 510 581 1.6E-16 T 29-03-2018 A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Gene3D G3DSA:3.40.50.300 331 509 1.3E-25 T 29-03-2018 A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 SMART SM00382 356 500 1.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Pfam PF08461 Ribonuclease R winged-helix domain 611 668 5.8E-5 T 29-03-2018 IPR013668 Ribonuclease R winged-helix domain A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 SUPERFAMILY SSF46785 598 671 3.68E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 Gene3D G3DSA:3.30.450.20 203 326 1.5E-11 T 29-03-2018 A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 SUPERFAMILY SSF52540 335 575 7.23E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02140 4a5fe3e07ed23bd9e29e4efd8eb3f550 674 SUPERFAMILY SSF55785 207 313 7.85E-8 T 29-03-2018 IPR000014 PAS domain A616_RS07575 0b9736f1dfa699e6e3b66ea7db5280bf 137 SUPERFAMILY SSF54427 3 136 2.2E-62 T 29-03-2018 IPR032710 NTF2-like domain A616_RS07575 0b9736f1dfa699e6e3b66ea7db5280bf 137 Gene3D G3DSA:3.10.450.50 10 137 4.2E-58 T 29-03-2018 A616_RS07575 0b9736f1dfa699e6e3b66ea7db5280bf 137 Pfam PF07080 Protein of unknown function (DUF1348) 7 137 6.9E-60 T 29-03-2018 IPR009783 Protein of unknown function DUF1348 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 7 209 5.8E-53 T 29-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 SUPERFAMILY SSF63862 149 211 7.85E-11 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 Gene3D G3DSA:2.60.120.320 121 213 4.7E-23 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 23 128 1.5E-20 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 146 204 1.0E-14 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 SUPERFAMILY SSF63999 4 131 2.22E-31 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 SMART SM00983 133 207 7.2E-15 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS30360 d44aac44320fa9c260125146ee12d179 213 Gene3D G3DSA:3.40.50.10240 2 120 5.2E-26 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS22195 1d623627ed8255a555a186be64d80716 140 Pfam PF13160 Protein of unknown function (DUF3995) 13 135 4.0E-41 T 29-03-2018 IPR025058 Protein of unknown function DUF3995 A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 Gene3D G3DSA:3.90.1150.10 378 478 1.4E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 Gene3D G3DSA:1.10.10.10 8 79 2.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 SMART SM00345 19 78 2.1E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 4.8E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 SUPERFAMILY SSF46785 11 88 4.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 Gene3D G3DSA:3.40.640.10 133 377 2.5E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 SUPERFAMILY SSF53383 117 476 3.72E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS03660 f4cecbc14c9099bdf4f78ca78eb575bc 485 Pfam PF00155 Aminotransferase class I and II 124 435 1.6E-24 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS15960 0db5b9e6896bda59292cf12bb5fd1034 131 PIRSF PIRSF029598 1 131 3.8E-31 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 A616_RS15960 0db5b9e6896bda59292cf12bb5fd1034 131 Pfam PF06146 Phosphate-starvation-inducible E 52 117 8.5E-10 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like A616_RS17450 5e7d77ab07f8c3f76f38c0ae1f21ca77 214 Pfam PF05709 Phage tail protein 38 209 1.1E-8 T 29-03-2018 IPR008841 Siphovirus-type tail component A616_RS13535 26f13d09e176dd0db6498e3236589f7d 427 PRINTS PR00758 Arsenical pump membrane protein signature 321 343 2.5E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS13535 26f13d09e176dd0db6498e3236589f7d 427 PRINTS PR00758 Arsenical pump membrane protein signature 363 388 2.5E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS13535 26f13d09e176dd0db6498e3236589f7d 427 PRINTS PR00758 Arsenical pump membrane protein signature 276 300 2.5E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS13535 26f13d09e176dd0db6498e3236589f7d 427 PRINTS PR00758 Arsenical pump membrane protein signature 175 198 2.5E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS13535 26f13d09e176dd0db6498e3236589f7d 427 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 2.5E-11 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS13535 26f13d09e176dd0db6498e3236589f7d 427 Pfam PF03600 Citrate transporter 16 367 1.6E-60 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 SUPERFAMILY SSF54373 223 309 5.1E-17 T 29-03-2018 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 Gene3D G3DSA:3.30.9.10 191 309 9.3E-31 T 29-03-2018 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 SUPERFAMILY SSF51905 2 223 7.77E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 SUPERFAMILY SSF51905 310 364 7.77E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 Pfam PF01266 FAD dependent oxidoreductase 3 348 1.9E-71 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 Gene3D G3DSA:3.50.50.60 2 190 2.5E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS05100 baa747afc58d60460d9c0e4b2d4c821c 367 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 5 353 5.8E-104 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 A616_RS07480 137a886d136b10939156d5477d2dfc36 195 Pfam PF13796 Putative sensor 14 188 1.8E-16 T 29-03-2018 IPR025828 Putative sensor domain A616_RS20960 c80b4d8e5d73250219aeb1c8d4f01167 169 Gene3D G3DSA:4.10.1070.10 55 154 7.1E-7 T 29-03-2018 A616_RS20960 c80b4d8e5d73250219aeb1c8d4f01167 169 Gene3D G3DSA:3.90.1340.10 1 54 1.1E-19 T 29-03-2018 IPR011083 Phage tail collar domain A616_RS20960 c80b4d8e5d73250219aeb1c8d4f01167 169 Pfam PF07484 Phage Tail Collar Domain 6 62 4.0E-24 T 29-03-2018 IPR011083 Phage tail collar domain A616_RS20960 c80b4d8e5d73250219aeb1c8d4f01167 169 SUPERFAMILY SSF88874 1 163 1.13E-41 T 29-03-2018 A616_RS11175 700df66d458661dd4974b301c51daf82 146 SUPERFAMILY SSF52833 1 144 3.82E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS11175 700df66d458661dd4974b301c51daf82 146 Gene3D G3DSA:3.40.30.10 1 144 3.2E-27 T 29-03-2018 A616_RS11175 700df66d458661dd4974b301c51daf82 146 Pfam PF00578 AhpC/TSA family 4 127 3.6E-24 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS11175 700df66d458661dd4974b301c51daf82 146 PIRSF PIRSF000239 1 145 1.5E-21 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS14715 110f21106f34c588143a05ecc3ba2553 599 SUPERFAMILY SSF55486 12 582 3.52E-102 T 29-03-2018 A616_RS14715 110f21106f34c588143a05ecc3ba2553 599 Pfam PF08439 Oligopeptidase F 114 183 5.5E-19 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A616_RS14715 110f21106f34c588143a05ecc3ba2553 599 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 7 597 5.6E-191 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 A616_RS14715 110f21106f34c588143a05ecc3ba2553 599 Pfam PF01432 Peptidase family M3 208 585 5.0E-37 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS14715 110f21106f34c588143a05ecc3ba2553 599 Gene3D G3DSA:1.10.1370.10 80 584 1.1E-24 T 29-03-2018 A616_RS22535 7ba69c2c4ceacc93eb924ac73aef46f8 306 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS22535 7ba69c2c4ceacc93eb924ac73aef46f8 306 Gene3D G3DSA:3.30.2350.10 81 297 3.7E-69 T 29-03-2018 A616_RS22535 7ba69c2c4ceacc93eb924ac73aef46f8 306 SUPERFAMILY SSF55120 74 296 1.92E-72 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS22535 7ba69c2c4ceacc93eb924ac73aef46f8 306 Gene3D G3DSA:3.10.290.10 3 73 9.8E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS22535 7ba69c2c4ceacc93eb924ac73aef46f8 306 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 294 2.5E-82 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS22535 7ba69c2c4ceacc93eb924ac73aef46f8 306 Pfam PF00849 RNA pseudouridylate synthase 89 239 4.4E-36 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 Gene3D G3DSA:3.50.50.60 179 295 4.2E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 SUPERFAMILY SSF51905 5 294 4.89E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.3E-19 T 29-03-2018 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 8.3E-19 T 29-03-2018 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 8.3E-19 T 29-03-2018 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 8.3E-19 T 29-03-2018 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 Gene3D G3DSA:3.50.50.60 1 178 4.2E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 165 2.5E-21 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 276 2.5E-21 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.5E-21 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 2.5E-21 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 2.5E-21 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07800 8873b3f67469ef34c6497e088a2375e4 303 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 280 4.8E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS08465 d280ca950b205a2461475ab04ebf5fab 245 Pfam PF04199 Putative cyclase 18 183 1.1E-32 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A616_RS08465 d280ca950b205a2461475ab04ebf5fab 245 Gene3D G3DSA:3.50.30.50 13 245 1.1E-47 T 29-03-2018 A616_RS08465 d280ca950b205a2461475ab04ebf5fab 245 SUPERFAMILY SSF102198 15 244 4.32E-53 T 29-03-2018 A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 Gene3D G3DSA:1.10.10.60 1 59 3.3E-15 T 29-03-2018 A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 SUPERFAMILY SSF46689 3 74 2.05E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 1.4E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 Gene3D G3DSA:1.10.357.10 60 199 1.4E-16 T 29-03-2018 A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 SUPERFAMILY SSF48498 77 189 5.19E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22920 578c049e8f7a1cb7a5eff33a3f76ec97 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 SUPERFAMILY SSF50249 16 157 1.05E-44 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 PIRSF PIRSF039101 1 506 2.9E-203 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 264 281 3.7E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 211 3.7E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 259 3.7E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 387 403 3.7E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 3.7E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 Gene3D G3DSA:2.40.50.140 17 157 5.9E-41 T 29-03-2018 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 Pfam PF01336 OB-fold nucleic acid binding domain 71 146 3.1E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 Pfam PF00152 tRNA synthetases class II (D, K and N) 165 502 8.0E-83 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 23 505 45.986 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 19 504 2.6E-221 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 Gene3D G3DSA:3.30.930.10 158 502 2.4E-107 T 29-03-2018 A616_RS01175 a2bc45dbfd9ee2d716f144db467588ef 506 SUPERFAMILY SSF55681 164 503 2.39E-122 T 29-03-2018 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.865 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 6.0E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 6.0E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 6.0E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 6.0E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.6E-52 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.1E-63 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 Gene3D G3DSA:3.90.1170.10 1 139 4.5E-55 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A616_RS01435 9bf09fd83b4173eaa7a715abff72e32e 144 SUPERFAMILY SSF54686 1 137 4.58E-60 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00825 Beta-ketoacyl synthase 1709 2123 2.8E-156 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00825 Beta-ketoacyl synthase 533 963 2.2E-140 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF53901 529 898 2.01E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF53901 939 958 2.01E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF47336 1469 1553 7.07E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 425 440 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:3.40.50.150 64 342 2.2E-19 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF47336 2361 2432 2.88E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:1.10.1200.10 2348 2442 6.9E-22 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:1.10.1200.10 1575 1673 2.7E-16 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:3.40.47.10 1959 2121 5.4E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:3.40.47.10 795 961 1.7E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF53901 2098 2110 3.9E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF53901 1704 2062 3.9E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF47336 1588 1720 3.4E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF08242 Methyltransferase domain 173 277 5.0E-15 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:3.40.47.10 1700 1956 3.9E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:3.40.47.10 523 792 1.8E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1857 1873 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF00550 Phosphopantetheine attachment site 2367 2431 2.3E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF00550 Phosphopantetheine attachment site 1477 1542 1.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF00550 Phosphopantetheine attachment site 1596 1660 5.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF00550 Phosphopantetheine attachment site 400 466 5.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF53335 1182 1363 2.09E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM01294 1476 1542 1.9E-4 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM01294 1594 1660 4.2E-5 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:3.40.50.150 1035 1412 2.8E-18 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF02353 Mycolic acid cyclopropane synthetase 1193 1322 2.4E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF47336 399 471 6.02E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF47336 515 543 6.02E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2390 2405 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SUPERFAMILY SSF53335 134 333 6.07E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 1168 1433 2.2E-96 T 29-03-2018 IPR020803 Polyketide synthase, methyltransferase domain A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:1.10.1200.10 353 474 2.9E-15 T 29-03-2018 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 788 903 1.2E-31 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1952 2069 5.0E-37 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 909 1023 2.5E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2073 2191 5.7E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00823 Phosphopantetheine attachment site 2366 2435 1.5E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00823 Phosphopantetheine attachment site 1475 1546 2.7E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00823 Phosphopantetheine attachment site 399 470 1.8E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 SMART SM00823 Phosphopantetheine attachment site 1593 1664 1.8E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1707 1944 4.7E-73 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 532 780 5.1E-73 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22030 e7df179f7be87edca0d4a4c6ad346d27 2452 Gene3D G3DSA:1.10.1200.10 1467 1549 5.0E-14 T 29-03-2018 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 SUPERFAMILY SSF89447 1 51 1.12E-14 T 29-03-2018 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 Gene3D G3DSA:2.10.260.10 1 49 2.5E-20 T 29-03-2018 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 179 3.1E-86 T 29-03-2018 IPR014213 Sporulation stage V, protein T A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 PIRSF PIRSF026579 1 180 3.5E-91 T 29-03-2018 IPR014213 Sporulation stage V, protein T A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.3E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 SMART SM00966 8 52 1.1E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 179 4.3E-46 T 29-03-2018 A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 SUPERFAMILY SSF55781 78 179 7.11E-8 T 29-03-2018 IPR029016 GAF domain-like A616_RS00715 9bf1ea4fe9c9b8537e24e9b7d7a04496 180 Gene3D G3DSA:3.30.450.40 58 180 3.2E-6 T 29-03-2018 IPR029016 GAF domain-like A616_RS25330 12c1beb34402c16448d411cf00452d0b 222 Gene3D G3DSA:3.40.50.620 3 222 2.5E-55 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS25330 12c1beb34402c16448d411cf00452d0b 222 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 3.9E-82 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A616_RS25330 12c1beb34402c16448d411cf00452d0b 222 PIRSF PIRSF006293 2 220 6.0E-79 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A616_RS25330 12c1beb34402c16448d411cf00452d0b 222 SUPERFAMILY SSF52402 3 211 4.63E-67 T 29-03-2018 A616_RS25330 12c1beb34402c16448d411cf00452d0b 222 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 217 51.512 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A616_RS25330 12c1beb34402c16448d411cf00452d0b 222 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 4.5E-86 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A616_RS14080 e500309e5e316d868edb42974278575a 163 SUPERFAMILY SSF89963 6 90 6.8E-29 T 29-03-2018 IPR007551 Protein of unknown function DUF520 A616_RS14080 e500309e5e316d868edb42974278575a 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.171 T 29-03-2018 IPR007551 Protein of unknown function DUF520 A616_RS14080 e500309e5e316d868edb42974278575a 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.0E-61 T 29-03-2018 IPR007551 Protein of unknown function DUF520 A616_RS14080 e500309e5e316d868edb42974278575a 163 SUPERFAMILY SSF89963 92 163 2.62E-25 T 29-03-2018 IPR007551 Protein of unknown function DUF520 A616_RS14080 e500309e5e316d868edb42974278575a 163 Gene3D G3DSA:3.30.70.860 99 163 1.2E-27 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain A616_RS14080 e500309e5e316d868edb42974278575a 163 Gene3D G3DSA:3.30.70.990 13 98 2.3E-30 T 29-03-2018 IPR035570 UPF0234 N-terminal domain A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 SUPERFAMILY SSF55383 613 672 8.37E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 Gene3D G3DSA:2.60.40.1280 28 153 1.7E-4 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 Gene3D G3DSA:2.60.40.1280 297 427 2.5E-8 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 Gene3D G3DSA:2.60.40.1280 154 296 3.1E-6 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 Pfam PF10989 Protein of unknown function (DUF2808) 42 143 2.9E-7 T 29-03-2018 IPR021256 Protein of unknown function DUF2808 A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 Pfam PF07833 Copper amine oxidase N-terminal domain 589 677 1.7E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS00740 1fb9eb6c6643e10cb75ced340d77f5a4 678 Gene3D G3DSA:3.30.457.10 606 667 7.6E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 ProSitePatterns PS00012 Phosphopantetheine attachment site. 129 144 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1329 1567 3.3E-76 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 197 430 2.0E-75 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF08659 KR domain 2465 2643 1.7E-39 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM01294 104 170 3.9E-6 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM01294 1206 1272 2.1E-11 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM01294 13 79 0.0013 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF53901 195 548 1.43E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:1.10.1200.10 1181 1282 2.8E-15 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.10.129.10 1937 2065 8.3E-23 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 438 555 4.6E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1575 1693 6.7E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF14765 Polyketide synthase dehydratase 1935 2230 5.8E-70 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.40.50.720 2457 2717 1.2E-29 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 ProSitePatterns PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 1806 1812 - T 29-03-2018 IPR003006 Immunoglobulin/major histocompatibility complex, conserved site A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF47336 100 210 4.06E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:1.10.1200.10 94 174 7.6E-16 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00823 Phosphopantetheine attachment site 102 174 1.4E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00823 Phosphopantetheine attachment site 1205 1276 7.4E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00823 Phosphopantetheine attachment site 11 83 3.2E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF53335 941 1131 3.24E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF51735 2462 2681 7.72E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF08242 Methyltransferase domain 972 1074 2.0E-14 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF47336 9 85 1.44E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF53901 1328 1685 5.46E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF51735 2248 2452 4.17E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2465 2645 3.8E-25 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.40.50.150 871 1142 7.4E-22 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF00550 Phosphopantetheine attachment site 15 79 2.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF00550 Phosphopantetheine attachment site 1208 1272 3.2E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF00550 Phosphopantetheine attachment site 106 170 4.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:1.10.1200.10 6 93 5.2E-14 T 29-03-2018 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1480 1496 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1231 1246 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.40.47.10 445 607 2.1E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.40.47.10 1582 1744 4.4E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SUPERFAMILY SSF47336 1202 1277 2.75E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1696 1805 7.4E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 559 673 7.9E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 343 359 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.40.47.10 189 442 3.9E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 Gene3D G3DSA:3.40.47.10 1322 1579 3.2E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00825 Beta-ketoacyl synthase 1331 1746 2.0E-176 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00825 Beta-ketoacyl synthase 199 609 2.5E-175 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 SMART SM00826 1935 2102 8.5E-21 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22050 625309de8f8872df8d2c85159e6d07d8 2741 ProSitePatterns PS00012 Phosphopantetheine attachment site. 38 53 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS03930 d9781646e545d83347708671168cf334 534 SUPERFAMILY SSF52172 1 143 2.85E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03930 d9781646e545d83347708671168cf334 534 SMART SM00342 444 527 3.0E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS03930 d9781646e545d83347708671168cf334 534 Pfam PF00072 Response regulator receiver domain 5 116 9.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03930 d9781646e545d83347708671168cf334 534 SUPERFAMILY SSF46689 480 529 1.93E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS03930 d9781646e545d83347708671168cf334 534 Gene3D G3DSA:3.40.50.2300 1 262 3.1E-37 T 29-03-2018 A616_RS03930 d9781646e545d83347708671168cf334 534 Gene3D G3DSA:3.90.1240.10 351 533 3.1E-31 T 29-03-2018 A616_RS03930 d9781646e545d83347708671168cf334 534 SMART SM00448 2 116 9.2E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03930 d9781646e545d83347708671168cf334 534 Pfam PF12833 Helix-turn-helix domain 451 528 1.3E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS13725 948020acc9db0b218a7862916af43e26 187 Gene3D G3DSA:1.10.286.10 6 53 1.1E-20 T 29-03-2018 A616_RS13725 948020acc9db0b218a7862916af43e26 187 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 113 123 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A616_RS13725 948020acc9db0b218a7862916af43e26 187 Gene3D G3DSA:3.30.1130.10 55 187 3.3E-62 T 29-03-2018 A616_RS13725 948020acc9db0b218a7862916af43e26 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 186 41.771 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A616_RS13725 948020acc9db0b218a7862916af43e26 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 64 80 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A616_RS13725 948020acc9db0b218a7862916af43e26 187 Pfam PF01227 GTP cyclohydrolase I 8 185 3.4E-81 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A616_RS13725 948020acc9db0b218a7862916af43e26 187 SUPERFAMILY SSF55620 3 186 1.85E-78 T 29-03-2018 A616_RS13725 948020acc9db0b218a7862916af43e26 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 8 186 5.8E-78 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Gene3D G3DSA:3.40.50.300 299 526 3.3E-34 T 29-03-2018 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 12 753 28.785 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Gene3D G3DSA:3.40.50.300 527 737 4.3E-31 T 29-03-2018 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 SUPERFAMILY SSF52540 337 729 6.21E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Gene3D G3DSA:1.10.150.20 105 144 9.2E-7 T 29-03-2018 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 SUPERFAMILY SSF47781 97 153 5.08E-7 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Pfam PF14490 Helix-hairpin-helix containing domain 156 247 5.1E-28 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Gene3D G3DSA:1.10.150.280 145 226 0.0023 T 29-03-2018 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 SMART SM00382 355 508 0.0015 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Pfam PF13538 UvrD-like helicase C-terminal domain 677 723 2.2E-14 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Pfam PF14520 Helix-hairpin-helix domain 107 152 4.5E-7 T 29-03-2018 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 16 750 5.5E-236 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 Pfam PF13604 AAA domain 342 535 1.0E-47 T 29-03-2018 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 SMART SM00278 198 217 450.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 SMART SM00278 134 153 0.69 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS10805 62684dee66c8803f126e41c0d92f8518 753 SMART SM00278 99 120 2400.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 5.4E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 5.4E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 5.4E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 5.4E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 Gene3D G3DSA:4.10.640.10 1 76 1.0E-32 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 SUPERFAMILY SSF46911 4 75 1.7E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 Pfam PF01084 Ribosomal protein S18 20 71 5.9E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 76 21.963 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 1.5E-34 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32175 e38365bcc0b4f070c7e8c87cd7b1db12 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 76 5.0E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 SUPERFAMILY SSF52540 7 243 6.58E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 498 178.533 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 257 443 3.3E-53 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 7 491 7.5E-165 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 233 1.1E-20 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 Gene3D G3DSA:3.40.50.880 245 491 1.1E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 SUPERFAMILY SSF52317 194 241 1.74E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 SUPERFAMILY SSF52317 269 441 1.74E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS07370 7d22acafd9532abd09d0787a07629f96 505 Gene3D G3DSA:3.40.50.300 3 244 4.3E-54 T 29-03-2018 A616_RS20570 f4bc3ec7cbca6fe14995fb7143856c1b 261 Gene3D G3DSA:3.20.20.370 38 261 1.2E-56 T 29-03-2018 A616_RS20570 f4bc3ec7cbca6fe14995fb7143856c1b 261 Pfam PF01522 Polysaccharide deacetylase 68 190 5.8E-36 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS20570 f4bc3ec7cbca6fe14995fb7143856c1b 261 SUPERFAMILY SSF88713 60 258 3.34E-63 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS20570 f4bc3ec7cbca6fe14995fb7143856c1b 261 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 36 258 9.9E-100 T 29-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA A616_RS29475 b373f032cf744fe411c2bdaac3b34bb4 221 Pfam PF13847 Methyltransferase domain 38 147 8.6E-19 T 29-03-2018 IPR025714 Methyltransferase domain A616_RS29475 b373f032cf744fe411c2bdaac3b34bb4 221 SUPERFAMILY SSF53335 4 214 5.33E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS29475 b373f032cf744fe411c2bdaac3b34bb4 221 Gene3D G3DSA:3.40.50.150 2 218 7.8E-27 T 29-03-2018 A616_RS00600 0ac22a37d8006d2f64eb02596acd42f1 91 Pfam PF01541 GIY-YIG catalytic domain 11 82 4.9E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS00600 0ac22a37d8006d2f64eb02596acd42f1 91 Gene3D G3DSA:3.40.1440.10 1 85 3.1E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS00600 0ac22a37d8006d2f64eb02596acd42f1 91 SUPERFAMILY SSF82771 10 81 7.85E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 Pfam PF01381 Helix-turn-helix 9 63 6.0E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 Gene3D G3DSA:1.10.260.40 1 87 7.2E-15 T 29-03-2018 A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 SMART SM00530 8 63 5.1E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 SUPERFAMILY SSF51182 48 180 4.1E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 Pfam PF07883 Cupin domain 108 176 4.6E-18 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 Gene3D G3DSA:2.60.120.10 89 181 7.5E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS27195 1392311ebf1c08d6f1e371f79d644b28 189 SUPERFAMILY SSF47413 4 68 5.36E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS23875 f08e6ad59ab2127a38e32b1c6c33d4e6 300 SUPERFAMILY SSF103481 42 142 3.53E-16 T 29-03-2018 A616_RS23875 f08e6ad59ab2127a38e32b1c6c33d4e6 300 SUPERFAMILY SSF103481 185 289 6.02E-14 T 29-03-2018 A616_RS23875 f08e6ad59ab2127a38e32b1c6c33d4e6 300 Pfam PF00892 EamA-like transporter family 15 138 5.5E-24 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS23875 f08e6ad59ab2127a38e32b1c6c33d4e6 300 Pfam PF00892 EamA-like transporter family 152 285 1.4E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 313 5.4E-136 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 SUPERFAMILY SSF52374 4 314 1.29E-102 T 29-03-2018 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 467 1.2E-182 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 SUPERFAMILY SSF47323 343 467 7.19E-35 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 SMART SM00840 355 419 1.8E-18 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 Gene3D G3DSA:1.20.120.640 306 409 3.4E-20 T 29-03-2018 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 Gene3D G3DSA:3.40.50.620 2 305 1.0E-93 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 468 39.882 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A616_RS01280 32ad7ee5b40061ab33963f061fc6c3e7 468 Pfam PF09190 DALR domain 355 416 6.9E-16 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A616_RS24355 01eba8c8303eb58db1bb9433dd3d11bb 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 254 1.1E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24355 01eba8c8303eb58db1bb9433dd3d11bb 265 Gene3D G3DSA:1.10.3720.10 9 263 4.0E-49 T 29-03-2018 A616_RS24355 01eba8c8303eb58db1bb9433dd3d11bb 265 SUPERFAMILY SSF161098 5 256 1.7E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07060 258747936bd5b14f921bd33db264a926 328 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 224 1.8E-5 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07060 258747936bd5b14f921bd33db264a926 328 SUPERFAMILY SSF81464 20 120 2.45E-22 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07060 258747936bd5b14f921bd33db264a926 328 PIRSF PIRSF000292 4 315 1.9E-107 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A616_RS07060 258747936bd5b14f921bd33db264a926 328 Gene3D G3DSA:2.60.40.420 118 280 1.4E-46 T 29-03-2018 IPR008972 Cupredoxin A616_RS07060 258747936bd5b14f921bd33db264a926 328 Pfam PF06481 COX Aromatic Rich Motif 244 284 5.8E-5 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 A616_RS07060 258747936bd5b14f921bd33db264a926 328 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 35 236 2.0E-44 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07060 258747936bd5b14f921bd33db264a926 328 Gene3D G3DSA:1.10.287.90 31 117 7.1E-21 T 29-03-2018 A616_RS07060 258747936bd5b14f921bd33db264a926 328 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 16 240 5.7E-75 T 29-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 A616_RS07060 258747936bd5b14f921bd33db264a926 328 SUPERFAMILY SSF49503 127 266 3.59E-45 T 29-03-2018 IPR008972 Cupredoxin A616_RS07060 258747936bd5b14f921bd33db264a926 328 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 110 4.7E-5 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 143 2.9E-35 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 SUPERFAMILY SSF51735 147 312 4.42E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 Gene3D G3DSA:3.90.180.10 1 165 5.2E-51 T 29-03-2018 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 Pfam PF00107 Zinc-binding dehydrogenase 183 308 4.2E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 SMART SM00829 8 346 2.3E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 Gene3D G3DSA:3.40.50.10730 166 292 4.2E-26 T 29-03-2018 A616_RS08455 acc51825a0da11905d33da40b9dd0050 350 SUPERFAMILY SSF50129 1 182 5.33E-56 T 29-03-2018 IPR011032 GroES-like A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 260 274 6.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 288 6.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 329 6.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 310 6.6E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 SMART SM00388 112 178 1.4E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 Gene3D G3DSA:3.30.565.10 173 329 8.4E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 Gene3D G3DSA:1.20.1560.10 9 112 1.2E-4 T 29-03-2018 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 Gene3D G3DSA:1.10.287.130 113 172 2.9E-11 T 29-03-2018 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 SUPERFAMILY SSF55874 168 328 3.93E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 SUPERFAMILY SSF47384 105 177 1.45E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 223 328 1.4E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 Pfam PF00512 His Kinase A (phospho-acceptor) domain 114 176 1.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS01760 311baa9f11f4f3b44ad18dcc8dbf70b0 333 SMART SM00387 223 332 6.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24585 03823590f867026bf72b02a76abd2a3e 184 SUPERFAMILY SSF49879 83 182 2.3E-15 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 A616_RS24585 03823590f867026bf72b02a76abd2a3e 184 Pfam PF00498 FHA domain 100 176 5.3E-10 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A616_RS24585 03823590f867026bf72b02a76abd2a3e 184 Gene3D G3DSA:2.60.200.20 19 182 3.4E-15 T 29-03-2018 A616_RS11405 bb028cb702b15795e271bec5a82228a5 76 SUPERFAMILY SSF56349 8 70 1.18E-8 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS11405 bb028cb702b15795e271bec5a82228a5 76 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 11 48 2.0E-11 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS11405 bb028cb702b15795e271bec5a82228a5 76 Gene3D G3DSA:1.10.150.130 3 72 6.3E-12 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 SUPERFAMILY SSF118352 232 289 4.84E-17 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 290 37.014 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 Pfam PF01430 Hsp33 protein 3 279 3.9E-82 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 PIRSF PIRSF005261 1 289 8.8E-67 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 Gene3D G3DSA:3.55.30.10 2 233 1.5E-68 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 Gene3D G3DSA:3.90.1280.10 234 287 2.1E-19 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A616_RS01100 1609e65b50e796cdb16f49eaad7753b0 290 SUPERFAMILY SSF64397 3 239 8.11E-70 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 SMART SM00418 40 119 2.8E-27 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 Gene3D G3DSA:1.10.10.10 10 128 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 64 82 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.2E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.2E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 73 1.2E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 1.2E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 SUPERFAMILY SSF46785 28 116 1.65E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11970 eb13ad0b2d8418486a791e094171816b 129 Pfam PF01022 Bacterial regulatory protein, arsR family 47 93 3.2E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 Gene3D G3DSA:3.30.360.10 129 218 2.3E-36 T 29-03-2018 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 112 1.9E-25 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 134 151 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 5 250 1.1E-76 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 SUPERFAMILY SSF55347 113 221 2.83E-38 T 29-03-2018 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 PIRSF PIRSF000161 3 250 1.4E-67 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 250 29.415 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 SUPERFAMILY SSF51735 4 139 1.6E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 Gene3D G3DSA:3.40.50.720 3 128 1.5E-21 T 29-03-2018 A616_RS13920 91c0b8ff20cc032ab2b7288ce3c5cb04 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 115 248 8.6E-32 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS25910 9c7e32ebb592a7b367814cb88891b19f 326 Gene3D G3DSA:3.40.50.1980 168 326 2.5E-33 T 29-03-2018 A616_RS25910 9c7e32ebb592a7b367814cb88891b19f 326 Gene3D G3DSA:3.40.50.1980 38 167 7.1E-30 T 29-03-2018 A616_RS25910 9c7e32ebb592a7b367814cb88891b19f 326 Pfam PF01497 Periplasmic binding protein 70 298 3.9E-33 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS25910 9c7e32ebb592a7b367814cb88891b19f 326 SUPERFAMILY SSF53807 47 308 2.67E-63 T 29-03-2018 A616_RS20205 10afea5d36b011119e1405023cdd279e 258 Hamap MF_00052_B Ribonuclease HII [rnhB]. 75 254 33.593 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 A616_RS20205 10afea5d36b011119e1405023cdd279e 258 SUPERFAMILY SSF53098 64 257 1.82E-62 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS20205 10afea5d36b011119e1405023cdd279e 258 Pfam PF01351 Ribonuclease HII 78 252 2.6E-35 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain A616_RS20205 10afea5d36b011119e1405023cdd279e 258 Gene3D G3DSA:3.30.420.10 51 258 1.7E-66 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS05115 389ca0f31902be46ac7d00a7925c95d7 149 Gene3D G3DSA:3.90.79.10 18 143 6.8E-27 T 29-03-2018 A616_RS05115 389ca0f31902be46ac7d00a7925c95d7 149 Pfam PF00293 NUDIX domain 19 131 1.6E-21 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS05115 389ca0f31902be46ac7d00a7925c95d7 149 SUPERFAMILY SSF55811 7 142 4.33E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS05115 389ca0f31902be46ac7d00a7925c95d7 149 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS05115 389ca0f31902be46ac7d00a7925c95d7 149 PRINTS PR00502 NUDIX hydrolase family signature 44 58 6.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS05115 389ca0f31902be46ac7d00a7925c95d7 149 PRINTS PR00502 NUDIX hydrolase family signature 58 73 6.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:2.30.38.10 3400 3480 1.8E-24 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:2.30.38.10 4444 4525 3.3E-20 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.559.10 3665 3864 2.6E-38 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.559.10 4710 4910 5.0E-26 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM00823 Phosphopantetheine attachment site 3598 3667 0.026 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM00823 Phosphopantetheine attachment site 4643 4711 0.0046 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM00823 Phosphopantetheine attachment site 590 654 0.056 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM00823 Phosphopantetheine attachment site 1304 1376 1.8E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM00823 Phosphopantetheine attachment site 2553 2622 0.79 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3111 3514 3.4E-131 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4156 4559 1.5E-118 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.50.980 176 345 2.6E-33 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.50.980 4280 4443 2.3E-32 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.50.980 3235 3398 2.4E-30 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 2641 2802 5.56E-40 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4667 4682 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF56801 371 556 5.36E-95 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF56801 6 343 5.36E-95 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 930 1047 8.5E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM01294 1305 1372 4.1E-4 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3229 3240 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF47336 585 689 1.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 839 855 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 4725 4896 3.22E-34 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:1.10.1200.10 1297 1412 1.8E-16 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF47336 3590 3663 3.66E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00012 Phosphopantetheine attachment site. 613 628 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF47336 1302 1383 1.16E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.640.10 1707 1851 1.9E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00550 Phosphopantetheine attachment site 3600 3662 1.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00550 Phosphopantetheine attachment site 591 652 1.9E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00550 Phosphopantetheine attachment site 4647 4707 9.6E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00550 Phosphopantetheine attachment site 2555 2618 9.3E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00550 Phosphopantetheine attachment site 1306 1372 1.8E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF53383 1548 1956 6.05E-91 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00668 Condensation domain 4720 5169 1.4E-104 T 29-03-2018 IPR001242 Condensation domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00668 Condensation domain 3679 4113 7.4E-121 T 29-03-2018 IPR001242 Condensation domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00668 Condensation domain 2638 3066 3.2E-124 T 29-03-2018 IPR001242 Condensation domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00668 Condensation domain 2007 2445 6.5E-81 T 29-03-2018 IPR001242 Condensation domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SMART SM00825 Beta-ketoacyl synthase 677 1100 1.3E-179 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 675 922 4.1E-74 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:1.10.1200.10 2547 2618 1.2E-18 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:1.10.1200.10 3604 3664 2.9E-19 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 2010 2186 6.12E-36 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00202 Aminotransferase class-III 1567 1926 8.6E-51 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00501 AMP-binding enzyme 3090 3490 8.5E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00501 AMP-binding enzyme 4136 4535 5.2E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF00501 AMP-binding enzyme 20 454 4.8E-72 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF53901 671 795 3.57E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF53901 822 1040 3.57E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.300.30 448 554 2.0E-12 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:1.10.1200.10 570 666 1.1E-16 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 3685 3850 9.45E-42 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.90.1150.10 1531 1706 1.8E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 3858 4101 1.56E-59 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4274 4285 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF13193 AMP-binding enzyme C-terminal domain 4543 4616 5.5E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF13193 AMP-binding enzyme C-terminal domain 3498 3571 3.4E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.300.30 4531 4646 8.9E-35 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.300.30 3485 3603 8.4E-37 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF47336 2549 2619 8.64E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF56801 3050 3611 1.06E-151 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:1.10.1200.10 4647 4709 1.8E-18 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1050 1161 9.9E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.50.980 3081 3234 1.3E-47 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.50.980 3 175 6.0E-21 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.50.980 4126 4279 2.8E-40 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF56801 4093 4656 1.44E-146 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.47.10 937 1098 7.1E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.559.10 2619 2826 2.2E-35 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.90.1150.10 1852 1959 1.2E-4 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.30.559.10 1983 2195 5.0E-35 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 2811 3051 4.0E-60 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 4902 5158 3.56E-39 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:3.40.47.10 667 934 4.9E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 5024 5177 1.3E-45 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 Gene3D G3DSA:2.30.38.10 358 447 1.8E-21 T 29-03-2018 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1767 1803 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF47336 4636 4707 4.71E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18830 1312c76f36b83629bb3fb4448b10c90d 5186 SUPERFAMILY SSF52777 2193 2432 1.33E-36 T 29-03-2018 A616_RS09660 208703ce27e37917f862f75c60015aff 508 PIRSF PIRSF002869 1 499 1.0E-104 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 459 15.8 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 PRINTS PR01806 Virulence factor MviN signature 33 52 1.5E-20 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 PRINTS PR01806 Virulence factor MviN signature 401 418 1.5E-20 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 PRINTS PR01806 Virulence factor MviN signature 251 277 1.5E-20 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 PRINTS PR01806 Virulence factor MviN signature 126 150 1.5E-20 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 PRINTS PR01806 Virulence factor MviN signature 349 368 1.5E-20 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 Pfam PF03023 MviN-like protein 29 468 4.9E-85 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS09660 208703ce27e37917f862f75c60015aff 508 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 493 6.3E-96 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 SUPERFAMILY SSF46785 86 159 9.21E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 SUPERFAMILY SSF46785 1 80 1.39E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 185 32.413 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 Gene3D G3DSA:1.10.10.10 88 158 5.7E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 169 1.1E-48 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 Gene3D G3DSA:1.10.10.10 1 87 2.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 167 1.2E-54 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A616_RS13475 92a643a99c20b9e849f989a64aaecc45 194 PIRSF PIRSF019345 1 193 3.3E-53 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 Gene3D G3DSA:1.10.10.10 1 79 4.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 9.6E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 Pfam PF00155 Aminotransferase class I and II 145 464 1.8E-34 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 Gene3D G3DSA:3.90.1150.10 379 472 1.5E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 SMART SM00345 18 77 1.9E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 SUPERFAMILY SSF46785 11 81 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 SUPERFAMILY SSF53383 111 470 2.15E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS04870 cb1f0f1d12c79f18884faae45521f90e 475 Gene3D G3DSA:3.40.640.10 129 378 1.4E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS02990 61262570676a7a8fd98803524f9d72a7 171 SUPERFAMILY SSF53218 3 157 3.4E-39 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02990 61262570676a7a8fd98803524f9d72a7 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 4 145 2.6E-31 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02990 61262570676a7a8fd98803524f9d72a7 171 SMART SM00852 7 152 2.0E-22 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02990 61262570676a7a8fd98803524f9d72a7 171 Gene3D G3DSA:3.40.980.10 1 163 4.6E-38 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02990 61262570676a7a8fd98803524f9d72a7 171 Pfam PF00994 Probable molybdopterin binding domain 7 147 6.3E-30 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS15880 54846bbd50a6935320a80f81325a156d 462 Gene3D G3DSA:1.25.40.10 119 207 1.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 Gene3D G3DSA:1.10.260.40 5 76 3.1E-12 T 29-03-2018 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 Pfam PF01381 Helix-turn-helix 16 72 1.3E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 Gene3D G3DSA:1.25.40.10 208 290 0.0015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 SMART SM00530 15 72 3.1E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 SUPERFAMILY SSF48452 188 288 1.88E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 SUPERFAMILY SSF48452 116 155 1.88E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS15880 54846bbd50a6935320a80f81325a156d 462 SUPERFAMILY SSF47413 10 78 3.38E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 548 3.1E-154 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 Pfam PF00733 Asparagine synthase 240 611 1.9E-98 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 Gene3D G3DSA:3.60.20.10 1 219 3.5E-55 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 SUPERFAMILY SSF52402 232 377 3.21E-78 T 29-03-2018 A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 SUPERFAMILY SSF52402 468 606 3.21E-78 T 29-03-2018 A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 PIRSF PIRSF001589 1 624 5.4E-181 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 Gene3D G3DSA:3.40.50.620 220 618 4.2E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 Pfam PF13537 Glutamine amidotransferase domain 48 165 6.2E-41 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A616_RS11260 5145c04e7e17346d91cd580b70f7cb30 641 SUPERFAMILY SSF56235 1 222 1.72E-63 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS25650 c3d7fb17fcc4d23cd6748b3da45f6408 128 SUPERFAMILY SSF54593 4 126 9.54E-39 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS25650 c3d7fb17fcc4d23cd6748b3da45f6408 128 Gene3D G3DSA:3.10.180.10 1 128 5.5E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS25650 c3d7fb17fcc4d23cd6748b3da45f6408 128 PIRSF PIRSF021700 1 127 6.3E-39 T 29-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase A616_RS25650 c3d7fb17fcc4d23cd6748b3da45f6408 128 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 123 3.4E-37 T 29-03-2018 IPR028973 PhnB-like A616_RS02435 d91bdffde3aeb6203c43fd90fe9596e3 332 Gene3D G3DSA:3.30.200.20 1 85 3.8E-4 T 29-03-2018 A616_RS02435 d91bdffde3aeb6203c43fd90fe9596e3 332 Pfam PF01636 Phosphotransferase enzyme family 28 250 1.1E-15 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS02435 d91bdffde3aeb6203c43fd90fe9596e3 332 SUPERFAMILY SSF56112 2 294 1.28E-36 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS02435 d91bdffde3aeb6203c43fd90fe9596e3 332 Gene3D G3DSA:3.90.1200.10 86 329 2.3E-19 T 29-03-2018 A616_RS29500 4ec723c48fd2fc2f5be9bcca5810692e 295 Gene3D G3DSA:3.10.25.10 203 286 4.9E-20 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS29500 4ec723c48fd2fc2f5be9bcca5810692e 295 Gene3D G3DSA:3.40.50.170 1 202 1.8E-46 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS29500 4ec723c48fd2fc2f5be9bcca5810692e 295 Pfam PF00551 Formyl transferase 14 175 5.3E-22 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS29500 4ec723c48fd2fc2f5be9bcca5810692e 295 SUPERFAMILY SSF53328 1 202 7.72E-47 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS29500 4ec723c48fd2fc2f5be9bcca5810692e 295 Pfam PF02911 Formyl transferase, C-terminal domain 203 283 9.5E-20 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS29500 4ec723c48fd2fc2f5be9bcca5810692e 295 SUPERFAMILY SSF50486 202 283 5.65E-19 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A616_RS17835 605ddf13db99dc62a0d8b6f389c3541b 399 Pfam PF07690 Major Facilitator Superfamily 27 335 9.4E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS17835 605ddf13db99dc62a0d8b6f389c3541b 399 Gene3D G3DSA:1.20.1250.20 211 395 1.1E-14 T 29-03-2018 A616_RS17835 605ddf13db99dc62a0d8b6f389c3541b 399 SUPERFAMILY SSF103473 10 392 6.28E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS17835 605ddf13db99dc62a0d8b6f389c3541b 399 Gene3D G3DSA:1.20.1250.20 12 202 4.3E-27 T 29-03-2018 A616_RS15220 5666e4aee593fad621b280f5f493442e 354 Gene3D G3DSA:3.30.360.10 140 354 1.8E-43 T 29-03-2018 A616_RS15220 5666e4aee593fad621b280f5f493442e 354 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 125 7.5E-31 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS15220 5666e4aee593fad621b280f5f493442e 354 SUPERFAMILY SSF55347 135 317 5.07E-33 T 29-03-2018 A616_RS15220 5666e4aee593fad621b280f5f493442e 354 Gene3D G3DSA:3.40.50.720 1 139 7.4E-45 T 29-03-2018 A616_RS15220 5666e4aee593fad621b280f5f493442e 354 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 207 2.7E-8 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS15220 5666e4aee593fad621b280f5f493442e 354 SUPERFAMILY SSF51735 4 157 2.47E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS17515 6311bbec8a280234eb5b694229298c4b 457 Pfam PF00688 TGF-beta propeptide 100 198 3.6E-7 T 29-03-2018 IPR001111 TGF-beta, propeptide A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 SUPERFAMILY SSF48179 175 285 1.04E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 Gene3D G3DSA:1.10.3660.10 183 291 4.8E-28 T 29-03-2018 A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 SUPERFAMILY SSF55021 297 348 2.75E-8 T 29-03-2018 A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 SUPERFAMILY SSF51735 6 171 1.56E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 Pfam PF02153 Prephenate dehydrogenase 18 275 4.7E-75 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 Gene3D G3DSA:3.40.50.720 1 174 1.5E-28 T 29-03-2018 A616_RS13840 2ead48ac1dc88be07569514cf6679728 367 Gene3D G3DSA:3.30.70.260 296 359 1.3E-7 T 29-03-2018 A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 157 3.6E-46 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 Gene3D G3DSA:3.90.45.10 1 162 1.9E-54 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 PIRSF PIRSF004749 1 162 6.7E-51 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 PRINTS PR01576 Peptide deformylase signature 34 63 8.6E-28 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 PRINTS PR01576 Peptide deformylase signature 118 147 8.6E-28 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 PRINTS PR01576 Peptide deformylase signature 99 117 8.6E-28 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 PRINTS PR01576 Peptide deformylase signature 87 98 8.6E-28 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 Pfam PF01327 Polypeptide deformylase 3 148 4.1E-47 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 Hamap MF_00163 Peptide deformylase [def]. 2 162 28.978 T 29-03-2018 IPR023635 Peptide deformylase A616_RS04985 e11a76c5ca362f8e2940bd25c212ea4b 171 SUPERFAMILY SSF56420 3 151 2.22E-53 T 29-03-2018 IPR023635 Peptide deformylase A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF56801 5622 6182 1.31E-170 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 4339 4605 2.56E-60 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 5657 5810 7.2E-52 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 615 765 2.9E-31 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 5811 5970 8.3E-39 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 4763 4927 1.1E-33 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 3728 3885 2.0E-32 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 1651 1803 8.9E-41 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 2690 2848 2.5E-38 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 3134 3296 8.78E-44 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF47336 4075 4148 2.62E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 2088 2258 2.11E-45 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF47336 963 1036 2.45E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:1.10.1200.10 5133 5192 2.5E-21 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:1.10.1200.10 2014 2076 1.1E-21 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:1.10.1200.10 6175 6241 3.2E-21 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF47336 5119 5193 8.64E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 609 620 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6193 6208 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00550 Phosphopantetheine attachment site 3048 3111 1.4E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00550 Phosphopantetheine attachment site 4085 4148 1.8E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00550 Phosphopantetheine attachment site 6171 6234 4.4E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00550 Phosphopantetheine attachment site 2010 2073 4.2E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00550 Phosphopantetheine attachment site 5129 5192 4.8E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00550 Phosphopantetheine attachment site 973 1036 1.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF47336 3038 3144 2.36E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.559.10 5193 5401 1.8E-44 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.559.10 2077 2277 2.2E-46 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.559.10 5 211 1.9E-31 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.559.10 1042 1242 4.3E-39 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 3304 3552 2.89E-60 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SMART SM00823 Phosphopantetheine attachment site 4083 4152 4.5E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SMART SM00823 Phosphopantetheine attachment site 2008 2077 0.0018 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SMART SM00823 Phosphopantetheine attachment site 971 1040 2.4E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SMART SM00823 Phosphopantetheine attachment site 5127 5196 0.01 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SMART SM00823 Phosphopantetheine attachment site 6169 6238 9.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SMART SM00823 Phosphopantetheine attachment site 3046 3115 4.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00501 AMP-binding enzyme 3583 3975 3.0E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00501 AMP-binding enzyme 4618 5019 4.0E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00501 AMP-binding enzyme 2543 2938 6.3E-113 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00501 AMP-binding enzyme 1506 1900 2.0E-106 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00501 AMP-binding enzyme 5664 6060 1.7E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00501 AMP-binding enzyme 471 863 2.7E-99 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF53474 6243 6480 2.64E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1645 1656 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.1820 6245 6481 1.6E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF56801 428 984 1.09E-158 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 5384 5627 2.0E-57 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5806 5817 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 4163 4335 2.22E-44 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:2.30.38.10 766 855 3.1E-23 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 190 456 3.89E-47 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF56801 3545 4096 1.96E-158 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:2.30.38.10 5971 6050 7.2E-25 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:2.30.38.10 1810 1890 1.1E-23 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:2.30.38.10 4929 5009 2.6E-24 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:2.30.38.10 3886 3965 3.8E-26 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:2.30.38.10 2849 2928 2.0E-26 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1527 1924 1.7E-141 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4639 5043 4.7E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2564 2962 8.0E-137 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 887 2.3E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3604 3999 2.5E-138 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5685 6084 1.0E-137 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 13 188 1.89E-40 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF56801 2504 3059 1.22E-163 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF56801 4576 5139 1.1E-161 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4107 4122 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF13193 AMP-binding enzyme C-terminal domain 3983 4056 2.3E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF13193 AMP-binding enzyme C-terminal domain 6068 6142 6.1E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF13193 AMP-binding enzyme C-terminal domain 1908 1981 2.9E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF13193 AMP-binding enzyme C-terminal domain 5027 5100 2.7E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF13193 AMP-binding enzyme C-terminal domain 2946 3019 1.8E-5 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF13193 AMP-binding enzyme C-terminal domain 871 944 1.0E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 1050 1222 3.67E-44 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 5206 5378 1.56E-43 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2684 2695 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 1229 1469 4.22E-59 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF56801 1466 2021 5.1E-172 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF47336 6162 6234 6.02E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4757 4768 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.559.10 4153 4346 4.8E-39 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.559.10 3114 3309 1.1E-41 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2032 2047 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF52777 2264 2529 4.78E-56 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 3574 3727 3.0E-46 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 2534 2689 1.9E-49 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 4609 4762 7.6E-50 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 1497 1650 2.4E-48 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.40.50.980 461 614 1.2E-47 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.300.30 3970 4086 4.2E-41 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.300.30 5014 5132 5.4E-38 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.300.30 858 974 6.0E-39 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.300.30 2933 3049 6.5E-33 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.300.30 1895 2013 4.0E-41 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:3.30.300.30 6055 6174 1.1E-40 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00975 Thioesterase domain 6255 6374 5.1E-19 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 SUPERFAMILY SSF47336 2000 2073 1.83E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3722 3733 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:1.10.1200.10 4087 4152 2.7E-23 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:1.10.1200.10 3050 3113 2.9E-22 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Gene3D G3DSA:1.10.1200.10 975 1041 1.3E-23 T 29-03-2018 A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00668 Condensation domain 5209 5643 1.7E-128 T 29-03-2018 IPR001242 Condensation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00668 Condensation domain 1053 1485 6.2E-130 T 29-03-2018 IPR001242 Condensation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00668 Condensation domain 3128 3560 3.6E-132 T 29-03-2018 IPR001242 Condensation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00668 Condensation domain 2090 2523 7.9E-128 T 29-03-2018 IPR001242 Condensation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00668 Condensation domain 8 450 6.3E-113 T 29-03-2018 IPR001242 Condensation domain A616_RS15670 f115ae3b4a11ec3155cb5682848f3c29 6487 Pfam PF00668 Condensation domain 4165 4598 6.8E-128 T 29-03-2018 IPR001242 Condensation domain A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Gene3D G3DSA:1.10.287.950 445 684 1.3E-57 T 29-03-2018 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Gene3D G3DSA:1.10.287.950 346 444 1.7E-8 T 29-03-2018 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Gene3D G3DSA:3.30.450.20 187 301 1.1E-23 T 29-03-2018 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 422 451 4.9E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 535 564 4.9E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 SMART SM00304 324 379 1.5E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 SMART SM00304 596 680 87.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Gene3D G3DSA:3.30.450.20 29 186 1.6E-18 T 29-03-2018 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 SUPERFAMILY SSF58104 414 683 2.22E-75 T 29-03-2018 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 SUPERFAMILY SSF58104 354 381 2.22E-75 T 29-03-2018 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 SMART SM00283 408 683 4.6E-90 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Pfam PF00672 HAMP domain 327 375 2.4E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 453 636 5.4E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS09420 410ac409bae49393d8585392cbd9f55e 684 Pfam PF02743 Cache domain 35 286 2.1E-39 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 SMART SM00871 132 289 7.5E-24 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 SUPERFAMILY SSF55136 128 288 3.4E-23 T 29-03-2018 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 SUPERFAMILY SSF46689 57 115 6.27E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 Gene3D G3DSA:1.10.10.60 1 57 1.2E-15 T 29-03-2018 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 Pfam PF12833 Helix-turn-helix domain 27 105 6.7E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 Pfam PF14526 Integron-associated effector binding protein 135 288 1.2E-29 T 29-03-2018 IPR029441 Integron-associated effector binding protein A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 SUPERFAMILY SSF46689 4 55 3.0E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 Gene3D G3DSA:1.10.10.60 58 115 5.8E-13 T 29-03-2018 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 SMART SM00342 21 104 4.9E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS04790 6457b60a8324d14711bf6713debd89ed 289 Gene3D G3DSA:3.20.80.10 116 288 2.4E-34 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS24980 6a6e3add0ba4dac694cbfc541073425f 392 SUPERFAMILY SSF53067 93 381 2.54E-43 T 29-03-2018 A616_RS24980 6a6e3add0ba4dac694cbfc541073425f 392 Gene3D G3DSA:1.10.10.10 12 79 1.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24980 6a6e3add0ba4dac694cbfc541073425f 392 Pfam PF00480 ROK family 95 377 1.4E-44 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS24980 6a6e3add0ba4dac694cbfc541073425f 392 Gene3D G3DSA:3.30.420.40 80 204 3.2E-23 T 29-03-2018 A616_RS24980 6a6e3add0ba4dac694cbfc541073425f 392 SUPERFAMILY SSF46785 12 77 3.52E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24980 6a6e3add0ba4dac694cbfc541073425f 392 Gene3D G3DSA:3.30.420.40 205 389 4.0E-42 T 29-03-2018 A616_RS02800 55a478fc9ca694535816331983af2092 207 Gene3D G3DSA:3.10.450.50 57 204 6.3E-27 T 29-03-2018 A616_RS02800 55a478fc9ca694535816331983af2092 207 Pfam PF07366 SnoaL-like polyketide cyclase 78 201 1.7E-39 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain A616_RS02800 55a478fc9ca694535816331983af2092 207 SUPERFAMILY SSF54427 75 204 1.67E-35 T 29-03-2018 IPR032710 NTF2-like domain A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 Gene3D G3DSA:1.10.10.60 50 186 1.8E-10 T 29-03-2018 A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 SUPERFAMILY SSF46689 4 83 1.85E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.8E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 Gene3D G3DSA:1.10.10.60 3 49 1.2E-16 T 29-03-2018 A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS31905 fb8b90406931ba56a46847c0f82934b6 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS02985 5ae6d528845d1de7938161eac53bfa61 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 186 7.4E-41 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A616_RS02985 5ae6d528845d1de7938161eac53bfa61 192 SUPERFAMILY SSF100950 6 192 1.4E-51 T 29-03-2018 A616_RS02985 5ae6d528845d1de7938161eac53bfa61 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 7 186 1.8E-51 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A616_RS02985 5ae6d528845d1de7938161eac53bfa61 192 Gene3D G3DSA:3.40.50.10420 1 192 1.5E-59 T 29-03-2018 A616_RS02985 5ae6d528845d1de7938161eac53bfa61 192 PIRSF PIRSF006806 2 189 1.4E-45 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A616_RS17855 5f4566ff34283bb315ff1b17ab6a8cd4 391 Pfam PF07690 Major Facilitator Superfamily 15 319 1.1E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS17855 5f4566ff34283bb315ff1b17ab6a8cd4 391 SUPERFAMILY SSF103473 3 385 3.92E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS17855 5f4566ff34283bb315ff1b17ab6a8cd4 391 Gene3D G3DSA:1.20.1250.20 2 191 2.2E-23 T 29-03-2018 A616_RS17855 5f4566ff34283bb315ff1b17ab6a8cd4 391 Gene3D G3DSA:1.20.1250.20 196 391 1.2E-18 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 488 4.4E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 SUPERFAMILY SSF51905 195 505 1.23E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 3 509 1.7E-240 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Gene3D G3DSA:3.50.50.60 334 435 2.1E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Pfam PF13192 Thioredoxin domain 124 192 1.1E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Gene3D G3DSA:3.40.30.10 102 196 6.7E-6 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Gene3D G3DSA:3.50.50.60 436 509 1.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 4.9E-40 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 4.9E-40 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 4.9E-40 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 4.9E-40 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 4.9E-40 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 5.3E-64 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Gene3D G3DSA:3.50.50.60 197 333 8.2E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 SUPERFAMILY SSF52833 103 194 3.17E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 Gene3D G3DSA:3.40.30.10 2 93 1.7E-22 T 29-03-2018 A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 SUPERFAMILY SSF52833 3 100 4.58E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS08660 dcb773f279c48316cdb6025fc6dca9d5 509 PIRSF PIRSF000238 2 509 2.1E-254 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 A616_RS06540 d7a4610debffc26b33caceec1ce97798 385 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 7 378 5.3E-181 T 29-03-2018 IPR014230 Sporulation protein YhbH A616_RS06540 d7a4610debffc26b33caceec1ce97798 385 Gene3D G3DSA:3.40.50.410 208 374 1.6E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS06540 d7a4610debffc26b33caceec1ce97798 385 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 5 383 31.379 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 A616_RS06540 d7a4610debffc26b33caceec1ce97798 385 Pfam PF04285 Protein of unknown function (DUF444) 13 181 2.5E-33 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 A616_RS06540 d7a4610debffc26b33caceec1ce97798 385 Pfam PF04285 Protein of unknown function (DUF444) 192 380 3.2E-74 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 A616_RS06540 d7a4610debffc26b33caceec1ce97798 385 SUPERFAMILY SSF53300 213 338 1.72E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31435 3057cfb9f73d3a2131e55d065046991f 354 SUPERFAMILY SSF51445 68 261 2.73E-16 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS31435 3057cfb9f73d3a2131e55d065046991f 354 SUPERFAMILY SSF51445 315 342 2.73E-16 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS31435 3057cfb9f73d3a2131e55d065046991f 354 Pfam PF00704 Glycosyl hydrolases family 18 131 342 8.4E-12 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS31435 3057cfb9f73d3a2131e55d065046991f 354 Gene3D G3DSA:3.10.50.10 275 315 8.0E-11 T 29-03-2018 IPR029070 Chitinase insertion domain A616_RS31435 3057cfb9f73d3a2131e55d065046991f 354 Gene3D G3DSA:3.20.20.80 25 274 3.0E-16 T 29-03-2018 A616_RS07000 3fc49e39b6251a957ab660de687bbc94 233 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 8 180 4.2E-71 T 29-03-2018 IPR022301 Integral membrane protein YjbE A616_RS07000 3fc49e39b6251a957ab660de687bbc94 233 Pfam PF03741 Integral membrane protein TerC family 10 178 4.0E-47 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 A616_RS00340 a49206e55410bf5a5ba21192e2582a43 115 SUPERFAMILY SSF46785 6 103 5.46E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00340 a49206e55410bf5a5ba21192e2582a43 115 Pfam PF01638 HxlR-like helix-turn-helix 16 103 3.3E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS00340 a49206e55410bf5a5ba21192e2582a43 115 Gene3D G3DSA:1.10.10.10 14 115 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29595 ccb73471f5bc6008c0a6227c851e9409 261 Gene3D G3DSA:3.40.50.2020 87 261 2.0E-24 T 29-03-2018 A616_RS29595 ccb73471f5bc6008c0a6227c851e9409 261 SUPERFAMILY SSF53271 81 257 1.32E-17 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS07910 f046913119a0667b3f33a156c17a6807 209 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 8.2E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS07910 f046913119a0667b3f33a156c17a6807 209 SMART SM00418 8 93 2.1E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS07910 f046913119a0667b3f33a156c17a6807 209 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 130 195 1.0E-22 T 29-03-2018 IPR018656 Domain of unknown function DUF2087 A616_RS07910 f046913119a0667b3f33a156c17a6807 209 Gene3D G3DSA:1.10.10.10 1 116 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07910 f046913119a0667b3f33a156c17a6807 209 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 9.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS07910 f046913119a0667b3f33a156c17a6807 209 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 9.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS07910 f046913119a0667b3f33a156c17a6807 209 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 9.9E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS07910 f046913119a0667b3f33a156c17a6807 209 SUPERFAMILY SSF46785 3 203 8.96E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 239 1.3E-70 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 PIRSF PIRSF001430 1 244 2.5E-81 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 Gene3D G3DSA:3.30.70.580 1 105 3.5E-34 T 29-03-2018 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 Pfam PF01416 tRNA pseudouridine synthase 9 104 1.9E-12 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 Pfam PF01416 tRNA pseudouridine synthase 143 244 5.1E-30 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 36.197 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 SUPERFAMILY SSF55120 1 244 4.17E-87 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS01560 7da221c8383ef8941d55b2ed43802a56 244 Gene3D G3DSA:3.30.70.660 106 243 4.7E-40 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS21195 feb5c113f50af95a18490c693bb5b07d 257 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 10 164 6.8E-55 T 29-03-2018 IPR014240 Regulatory protein, YteA family A616_RS21195 feb5c113f50af95a18490c693bb5b07d 257 SUPERFAMILY SSF109635 6 90 2.22E-15 T 29-03-2018 A616_RS21195 feb5c113f50af95a18490c693bb5b07d 257 SUPERFAMILY SSF57716 91 119 5.13E-6 T 29-03-2018 A616_RS21195 feb5c113f50af95a18490c693bb5b07d 257 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 117 2.2E-8 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 3.5E-12 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 3.5E-12 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 3.5E-12 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 356 49.09 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 Gene3D G3DSA:3.50.30.20 1 139 2.5E-60 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 2.4E-36 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 2.4E-36 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 2.4E-36 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 2.4E-36 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 2.4E-36 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 Pfam PF00117 Glutamine amidotransferase class-I 174 350 3.8E-47 T 29-03-2018 IPR017926 Glutamine amidotransferase A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 1.3E-52 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 SMART SM01097 1 131 5.1E-87 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 SUPERFAMILY SSF52317 150 354 4.95E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 353 6.1E-148 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 SUPERFAMILY SSF52021 1 142 8.5E-58 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 Gene3D G3DSA:3.40.50.880 140 357 8.1E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00097 Anthranilate synthase component II signature 327 340 4.9E-7 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00097 Anthranilate synthase component II signature 241 252 4.9E-7 T 29-03-2018 A616_RS21005 0c4a36350b7842840e53d87ddcb4f21d 365 PRINTS PR00097 Anthranilate synthase component II signature 214 223 4.9E-7 T 29-03-2018 A616_RS11330 96890d753fe869d9db2cdc3a5b6e8bea 256 Gene3D G3DSA:3.40.50.1820 1 254 6.0E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS11330 96890d753fe869d9db2cdc3a5b6e8bea 256 SUPERFAMILY SSF53474 4 255 3.69E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS11330 96890d753fe869d9db2cdc3a5b6e8bea 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 1.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS11330 96890d753fe869d9db2cdc3a5b6e8bea 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS11330 96890d753fe869d9db2cdc3a5b6e8bea 256 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 1.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS11330 96890d753fe869d9db2cdc3a5b6e8bea 256 Pfam PF00561 alpha/beta hydrolase fold 23 235 2.3E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 SUPERFAMILY SSF55874 513 693 1.44E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 Gene3D G3DSA:1.10.287.130 448 517 8.4E-15 T 29-03-2018 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 SMART SM00388 458 523 2.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 Gene3D G3DSA:2.60.120.260 49 228 3.0E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 SUPERFAMILY SSF47384 443 524 1.08E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 Pfam PF00512 His Kinase A (phospho-acceptor) domain 458 522 3.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 SUPERFAMILY SSF49785 53 195 6.63E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 Gene3D G3DSA:3.30.565.10 518 691 4.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 Pfam PF07695 7TM diverse intracellular signalling 213 409 8.7E-21 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 SMART SM00387 574 691 5.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 575 689 1.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 688 2.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 616 630 2.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 644 2.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25505 8216ffafbba9d7cd4bfcb3237d9900f6 703 PRINTS PR00344 Bacterial sensor protein C-terminal signature 651 669 2.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08105 d6f87f3b9e2bade3147ee3830e9e27c8 479 Gene3D G3DSA:1.10.10.630 322 400 9.1E-8 T 29-03-2018 IPR034829 DnaD-like domain A616_RS08105 d6f87f3b9e2bade3147ee3830e9e27c8 479 Pfam PF07261 Replication initiation and membrane attachment 330 402 9.9E-8 T 29-03-2018 IPR006343 DnaD domain A616_RS05430 c324e1e799c2be6396e632914e04be6a 178 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 164 175 - T 29-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A616_RS05430 c324e1e799c2be6396e632914e04be6a 178 Gene3D G3DSA:2.60.40.200 28 177 1.0E-36 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A616_RS05430 c324e1e799c2be6396e632914e04be6a 178 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 41 175 4.0E-33 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A616_RS05430 c324e1e799c2be6396e632914e04be6a 178 SUPERFAMILY SSF49329 40 175 4.19E-38 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 Gene3D G3DSA:3.40.50.300 285 551 1.4E-58 T 29-03-2018 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 Pfam PF16326 ABC transporter C-terminal domain 563 628 6.8E-15 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 SMART SM00382 28 231 3.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 SMART SM00382 343 515 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 SUPERFAMILY SSF52540 313 529 1.54E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 Pfam PF00005 ABC transporter 335 469 4.4E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 Pfam PF00005 ABC transporter 20 187 1.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 Gene3D G3DSA:3.40.50.300 1 284 2.2E-56 T 29-03-2018 A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 Pfam PF12848 ABC transporter 226 301 5.9E-13 T 29-03-2018 IPR032781 ABC-transporter extension domain A616_RS11115 ac5e22bdfe72c6dc216b44b1eb6e355c 638 SUPERFAMILY SSF52540 4 240 2.4E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22095 4eae5dcc4242a165b2ca6396dd5582f2 44 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 9 44 2.4E-11 T 29-03-2018 IPR009229 Staphylococcal AgrD A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 Gene3D G3DSA:1.25.40.10 156 279 8.8E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 SUPERFAMILY SSF47413 10 62 2.42E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 SMART SM00530 7 64 2.4E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 SUPERFAMILY SSF48452 186 364 9.7E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 Pfam PF01381 Helix-turn-helix 11 60 2.7E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 Gene3D G3DSA:1.25.40.10 280 383 3.0E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS16930 d634fc5c9f5ba4050d5a6641f3c7c45f 413 Gene3D G3DSA:1.10.260.40 1 102 2.9E-10 T 29-03-2018 A616_RS08710 9a3bdd222badb16ff683839ee9df305d 193 SUPERFAMILY SSF51206 6 138 1.18E-21 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS08710 9a3bdd222badb16ff683839ee9df305d 193 Pfam PF00027 Cyclic nucleotide-binding domain 30 118 9.3E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS08710 9a3bdd222badb16ff683839ee9df305d 193 SMART SM00100 11 133 1.1E-7 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS08710 9a3bdd222badb16ff683839ee9df305d 193 Gene3D G3DSA:2.60.120.10 5 140 1.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS08710 9a3bdd222badb16ff683839ee9df305d 193 Gene3D G3DSA:1.10.10.10 141 190 0.0025 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13550 0c2e146ec7141cff1882adf6fcb55573 68 SUPERFAMILY SSF54862 1 67 6.63E-13 T 29-03-2018 A616_RS13550 0c2e146ec7141cff1882adf6fcb55573 68 Gene3D G3DSA:3.30.70.20 1 68 3.9E-9 T 29-03-2018 A616_RS13550 0c2e146ec7141cff1882adf6fcb55573 68 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A616_RS13550 0c2e146ec7141cff1882adf6fcb55573 68 PRINTS PR00352 3Fe-4S ferredoxin signature 53 65 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A616_RS13550 0c2e146ec7141cff1882adf6fcb55573 68 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-9 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A616_RS13550 0c2e146ec7141cff1882adf6fcb55573 68 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 67 7.1E-22 T 29-03-2018 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 Gene3D G3DSA:1.25.40.20 118 202 1.9E-21 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SUPERFAMILY SSF48403 4 200 2.26E-45 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 Gene3D G3DSA:1.25.40.20 1 117 2.2E-26 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SMART SM00248 138 172 21.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SMART SM00248 71 100 19.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SMART SM00248 5 34 1000.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SMART SM00248 107 134 1900.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SMART SM00248 38 67 0.066 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 SMART SM00248 176 202 3300.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 Pfam PF12796 Ankyrin repeats (3 copies) 112 201 2.3E-11 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24895 e8fb62c1e8e335a1e646605138f80d2e 202 Pfam PF12796 Ankyrin repeats (3 copies) 12 98 3.0E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS20720 0f9d676f0dac3ad62530241abb8872b2 240 PIRSF PIRSF039085 1 240 6.5E-111 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS20720 0f9d676f0dac3ad62530241abb8872b2 240 SMART SM00382 26 213 6.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20720 0f9d676f0dac3ad62530241abb8872b2 240 SUPERFAMILY SSF52540 1 235 6.59E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20720 0f9d676f0dac3ad62530241abb8872b2 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS20720 0f9d676f0dac3ad62530241abb8872b2 240 Gene3D G3DSA:3.40.50.300 1 240 9.5E-80 T 29-03-2018 A616_RS20720 0f9d676f0dac3ad62530241abb8872b2 240 Pfam PF00005 ABC transporter 17 165 1.1E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08230 ef90da42f62b7b1d060286564a5a1fcc 339 SUPERFAMILY SSF46689 284 332 5.82E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS08230 ef90da42f62b7b1d060286564a5a1fcc 339 SMART SM00342 249 331 8.8E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08230 ef90da42f62b7b1d060286564a5a1fcc 339 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 24 204 4.6E-34 T 29-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal A616_RS08230 ef90da42f62b7b1d060286564a5a1fcc 339 Pfam PF12833 Helix-turn-helix domain 256 331 2.6E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08230 ef90da42f62b7b1d060286564a5a1fcc 339 Gene3D G3DSA:1.10.10.60 41 283 0.18 T 29-03-2018 A616_RS08230 ef90da42f62b7b1d060286564a5a1fcc 339 Gene3D G3DSA:1.10.10.60 284 334 8.6E-14 T 29-03-2018 A616_RS13835 c3c6dc0f7a5082a9186cf0f75a7476b5 364 Gene3D G3DSA:3.40.640.10 44 249 1.6E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS13835 c3c6dc0f7a5082a9186cf0f75a7476b5 364 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 358 3.7E-114 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A616_RS13835 c3c6dc0f7a5082a9186cf0f75a7476b5 364 SUPERFAMILY SSF53383 15 358 1.93E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS13835 c3c6dc0f7a5082a9186cf0f75a7476b5 364 Pfam PF00155 Aminotransferase class I and II 29 353 2.3E-64 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS13835 c3c6dc0f7a5082a9186cf0f75a7476b5 364 Gene3D G3DSA:3.90.1150.10 250 359 1.9E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS13835 c3c6dc0f7a5082a9186cf0f75a7476b5 364 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 62.335 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A616_RS01470 a2982610ceda452fcc4606e8b1e7857d 132 SUPERFAMILY SSF56047 2 132 5.23E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01470 a2982610ceda452fcc4606e8b1e7857d 132 Gene3D G3DSA:3.30.1490.10 70 130 1.2E-22 T 29-03-2018 A616_RS01470 a2982610ceda452fcc4606e8b1e7857d 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01470 a2982610ceda452fcc4606e8b1e7857d 132 Gene3D G3DSA:3.30.1370.30 1 67 1.2E-28 T 29-03-2018 A616_RS01470 a2982610ceda452fcc4606e8b1e7857d 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.745 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01470 a2982610ceda452fcc4606e8b1e7857d 132 Pfam PF00410 Ribosomal protein S8 5 132 2.1E-54 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 SMART SM00448 4 115 9.1E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 SMART SM01012 131 186 5.2E-16 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 Pfam PF00072 Response regulator receiver domain 6 115 2.5E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 PIRSF PIRSF036382 1 192 4.6E-62 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 Gene3D G3DSA:3.40.50.2300 1 145 1.6E-37 T 29-03-2018 A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 Gene3D G3DSA:1.10.10.10 146 187 4.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 SUPERFAMILY SSF52172 2 186 1.57E-52 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS30720 6c249830473f99b0781c81f6ad106d52 196 Pfam PF03861 ANTAR domain 134 186 9.5E-17 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:2.20.25.90 263 315 2.3E-18 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:3.40.50.740 316 513 9.6E-45 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 SUPERFAMILY SSF53706 251 771 7.85E-195 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 SMART SM00929 83 124 8.0E-9 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:3.10.20.30 1 116 2.4E-10 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 258 311 2.2E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 SUPERFAMILY SSF54862 128 214 4.05E-18 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 PIRSF PIRSF036643 1 965 0.0 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Pfam PF00037 4Fe-4S binding domain 185 205 2.1E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:1.10.1060.10 168 262 8.3E-8 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:3.30.70.20 120 167 3.5E-4 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 SMART SM00926 257 311 8.0E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 75 1.5E-14 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:2.40.40.20 783 933 1.1E-29 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Pfam PF00384 Molybdopterin oxidoreductase 314 737 2.6E-83 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 262 931 2.1E-257 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 190 201 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS15950 6f4170f1d705437187a37d34440392c6 983 SUPERFAMILY SSF50692 788 933 1.84E-35 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 85 122 2.0E-9 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 SUPERFAMILY SSF54292 4 124 5.81E-29 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Gene3D G3DSA:3.40.50.740 514 782 1.9E-81 T 29-03-2018 A616_RS15950 6f4170f1d705437187a37d34440392c6 983 Pfam PF01568 Molydopterin dinucleotide binding domain 821 927 2.4E-20 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 SUPERFAMILY SSF46785 137 204 2.96E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 SMART SM00419 150 198 8.5E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 Gene3D G3DSA:2.60.120.10 6 124 1.8E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 Pfam PF00027 Cyclic nucleotide-binding domain 23 105 2.2E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 Pfam PF13545 Crp-like helix-turn-helix domain 139 203 9.8E-15 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 SUPERFAMILY SSF51206 11 129 1.96E-20 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS16195 15feb72ad4be2e293094b1c1bc682f48 222 Gene3D G3DSA:1.10.10.10 125 205 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 SUPERFAMILY SSF52518 2 205 5.89E-71 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 SMART SM00861 5 180 1.8E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 179 2.1E-50 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 Pfam PF02780 Transketolase, C-terminal domain 195 317 1.2E-37 T 29-03-2018 IPR033248 Transketolase, C-terminal domain A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 Gene3D G3DSA:3.40.50.920 196 326 1.9E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 SUPERFAMILY SSF52922 190 324 4.06E-41 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS15255 f7659fabdb5d0ab26e6fa191b82620ef 327 Gene3D G3DSA:3.40.50.970 1 195 2.0E-70 T 29-03-2018 A616_RS26230 c6625e262640c57cd9edb16764854240 498 SUPERFAMILY SSF52949 10 182 1.12E-23 T 29-03-2018 A616_RS26230 c6625e262640c57cd9edb16764854240 498 Gene3D G3DSA:3.40.220.10 1 169 3.7E-29 T 29-03-2018 A616_RS26230 c6625e262640c57cd9edb16764854240 498 Gene3D G3DSA:3.40.630.10 170 496 1.7E-125 T 29-03-2018 A616_RS26230 c6625e262640c57cd9edb16764854240 498 SUPERFAMILY SSF53187 179 494 4.87E-111 T 29-03-2018 A616_RS26230 c6625e262640c57cd9edb16764854240 498 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 490 1.7E-114 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 9.8E-53 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 PRINTS PR00481 Cytosol aminopeptidase signature 342 362 9.8E-53 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 9.8E-53 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 PRINTS PR00481 Cytosol aminopeptidase signature 320 341 9.8E-53 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 9.8E-53 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 146 8.2E-22 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A616_RS26230 c6625e262640c57cd9edb16764854240 498 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 498 34.285 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A616_RS05490 a801e2407fcc3d53c61c595e32b1020e 263 Gene3D G3DSA:3.30.460.10 2 256 1.9E-9 T 29-03-2018 A616_RS05490 a801e2407fcc3d53c61c595e32b1020e 263 Pfam PF13427 Domain of unknown function (DUF4111) 184 246 8.1E-10 T 29-03-2018 IPR025184 Domain of unknown function DUF4111 A616_RS05490 a801e2407fcc3d53c61c595e32b1020e 263 SUPERFAMILY SSF81301 20 75 1.43E-6 T 29-03-2018 A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 Gene3D G3DSA:3.40.50.980 176 329 2.1E-42 T 29-03-2018 A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 Gene3D G3DSA:3.30.300.30 413 521 4.7E-28 T 29-03-2018 A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 505 1.9E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 Gene3D G3DSA:3.40.50.980 1 175 8.0E-42 T 29-03-2018 A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 Pfam PF00501 AMP-binding enzyme 9 418 5.3E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 Gene3D G3DSA:2.30.38.10 330 411 9.5E-24 T 29-03-2018 A616_RS09380 29a9c7e224b97f58623a8c7911a3bbf8 523 SUPERFAMILY SSF56801 3 515 4.97E-149 T 29-03-2018 A616_RS18770 296e8dfcafd230156435eb667b2cf5e5 502 SUPERFAMILY SSF53720 9 488 7.72E-151 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS18770 296e8dfcafd230156435eb667b2cf5e5 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS18770 296e8dfcafd230156435eb667b2cf5e5 502 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 11 486 2.5E-188 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 A616_RS18770 296e8dfcafd230156435eb667b2cf5e5 502 Pfam PF00171 Aldehyde dehydrogenase family 18 482 3.5E-145 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS18770 296e8dfcafd230156435eb667b2cf5e5 502 Gene3D G3DSA:3.40.309.10 269 464 9.6E-58 T 29-03-2018 A616_RS18770 296e8dfcafd230156435eb667b2cf5e5 502 Gene3D G3DSA:3.40.605.10 1 268 5.9E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS09195 349dd6a00348eeae605000ee7e096f1a 407 SUPERFAMILY SSF51338 23 69 2.41E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09195 349dd6a00348eeae605000ee7e096f1a 407 SUPERFAMILY SSF51338 222 233 2.41E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09195 349dd6a00348eeae605000ee7e096f1a 407 Gene3D G3DSA:3.20.20.140 76 360 1.6E-29 T 29-03-2018 A616_RS09195 349dd6a00348eeae605000ee7e096f1a 407 SUPERFAMILY SSF51556 70 373 9.32E-69 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS09195 349dd6a00348eeae605000ee7e096f1a 407 Pfam PF07969 Amidohydrolase family 208 397 1.3E-12 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS09195 349dd6a00348eeae605000ee7e096f1a 407 Gene3D G3DSA:2.30.40.10 1 75 2.2E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS15650 ff339b078a1bc1c512632bdb01788f15 396 SUPERFAMILY SSF103473 5 388 4.84E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS15650 ff339b078a1bc1c512632bdb01788f15 396 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS15650 ff339b078a1bc1c512632bdb01788f15 396 Gene3D G3DSA:1.20.1250.20 5 200 5.6E-29 T 29-03-2018 A616_RS15650 ff339b078a1bc1c512632bdb01788f15 396 Gene3D G3DSA:1.20.1250.20 201 390 4.1E-28 T 29-03-2018 A616_RS15650 ff339b078a1bc1c512632bdb01788f15 396 Pfam PF07690 Major Facilitator Superfamily 15 326 1.8E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 248 387 9.4E-72 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 SUPERFAMILY SSF55973 125 247 1.88E-53 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Gene3D G3DSA:3.30.300.10 15 147 6.1E-46 T 29-03-2018 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 SUPERFAMILY SSF55973 248 396 1.57E-71 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Pfam PF02772 S-adenosylmethionine synthetase, central domain 130 246 8.2E-50 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 SUPERFAMILY SSF55973 8 113 4.71E-48 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 6 398 59.735 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Gene3D G3DSA:3.30.300.10 148 248 5.8E-49 T 29-03-2018 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 8 105 1.7E-44 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 PIRSF PIRSF000497 2 399 6.0E-180 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 131 141 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 Gene3D G3DSA:3.30.300.10 261 400 1.4E-50 T 29-03-2018 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 274 282 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS29625 0c7f934b436a9512d996a97f0575b51b 401 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 9 396 1.3E-187 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Gene3D G3DSA:3.30.450.20 33 172 1.1E-19 T 29-03-2018 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Pfam PF02743 Cache domain 43 265 5.5E-27 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Gene3D G3DSA:3.30.450.20 173 280 4.6E-15 T 29-03-2018 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Gene3D G3DSA:1.10.287.950 299 411 1.5E-10 T 29-03-2018 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Gene3D G3DSA:1.10.287.950 412 660 2.2E-54 T 29-03-2018 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 SUPERFAMILY SSF58104 390 658 5.23E-71 T 29-03-2018 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 SUPERFAMILY SSF58104 324 357 5.23E-71 T 29-03-2018 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 SUPERFAMILY SSF103190 130 188 1.26E-8 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 428 610 3.5E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 SMART SM00283 384 659 5.1E-80 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 Pfam PF00672 HAMP domain 303 351 6.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS06965 d992d00eaf0a4414bd79449ae331031a 660 SMART SM00304 303 355 6.7E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 Pfam PF13531 Bacterial extracellular solute-binding protein 63 304 4.5E-46 T 29-03-2018 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 45 350 4.7E-155 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 169 177 - T 29-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 Gene3D G3DSA:3.40.190.10 150 272 1.9E-28 T 29-03-2018 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 Gene3D G3DSA:3.40.190.10 273 353 7.2E-22 T 29-03-2018 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 Gene3D G3DSA:3.40.190.10 44 149 3.0E-26 T 29-03-2018 A616_RS14205 51c014e46f5b392416e63ef07c5dde86 353 SUPERFAMILY SSF53850 46 351 3.42E-93 T 29-03-2018 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 486 1.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 SMART SM00388 266 333 5.1E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 267 332 7.5E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 SUPERFAMILY SSF55874 322 486 1.2E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 Gene3D G3DSA:1.10.287.130 249 329 3.2E-19 T 29-03-2018 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 Gene3D G3DSA:3.30.450.20 43 177 0.004 T 29-03-2018 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 Pfam PF00672 HAMP domain 205 254 7.1E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 SMART SM00387 375 488 2.7E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 Gene3D G3DSA:3.30.565.10 338 497 1.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 SMART SM00304 205 258 3.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 SUPERFAMILY SSF47384 255 332 7.46E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 5.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 5.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 5.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 441 5.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS06685 67a9d82c32bd3a88a57bf41d14e7dd5e 498 SUPERFAMILY SSF158472 205 255 4.45E-7 T 29-03-2018 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Gene3D G3DSA:3.30.930.10 353 588 2.2E-56 T 29-03-2018 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Gene3D G3DSA:3.30.930.10 138 350 2.3E-57 T 29-03-2018 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 6 585 2.4E-253 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 SUPERFAMILY SSF55261 296 422 1.08E-43 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 4.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 4.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 214 227 4.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 209 4.7E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 SUPERFAMILY SSF50249 5 110 4.38E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Pfam PF01336 OB-fold nucleic acid binding domain 22 107 5.8E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Gene3D G3DSA:2.40.50.140 2 113 6.5E-26 T 29-03-2018 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 5 587 34.807 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 SUPERFAMILY SSF55681 119 299 4.98E-111 T 29-03-2018 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 SUPERFAMILY SSF55681 427 585 4.98E-111 T 29-03-2018 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Pfam PF00152 tRNA synthetases class II (D, K and N) 124 560 2.5E-111 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10770 669b17ad6b96f28bddb2e0542bf8c2ef 596 Pfam PF02938 GAD domain 315 408 1.2E-28 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A616_RS23070 44e5e71f4e4dc36ae3bc0b5234d0400c 272 Gene3D G3DSA:3.40.50.1820 1 270 7.9E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS23070 44e5e71f4e4dc36ae3bc0b5234d0400c 272 SUPERFAMILY SSF53474 3 265 1.22E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS23070 44e5e71f4e4dc36ae3bc0b5234d0400c 272 Pfam PF12697 Alpha/beta hydrolase family 21 255 4.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS23070 44e5e71f4e4dc36ae3bc0b5234d0400c 272 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 92 99 - T 29-03-2018 IPR018202 Serine carboxypeptidase, serine active site A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Gene3D G3DSA:1.10.268.10 344 486 6.6E-54 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 SUPERFAMILY SSF101904 498 819 1.02E-116 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Gene3D G3DSA:2.120.10.90 498 822 5.5E-133 T 29-03-2018 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 806 25.257 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 SUPERFAMILY SSF56719 30 486 1.09E-185 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 SMART SM00434 11 464 9.4E-295 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 804 0.0 T 29-03-2018 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Gene3D G3DSA:3.30.1360.40 236 332 3.6E-39 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Gene3D G3DSA:3.90.199.10 34 215 1.1E-87 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 471 1.2E-164 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 610 653 1.7E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 708 754 2.3E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 657 703 1.8E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 758 798 3.0E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 550 2.0E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS00180 696db7c3027e11c5a5240039c82a96d8 844 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 553 603 1.4E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 12 638 3.0E-231 T 29-03-2018 IPR011927 Stage V sporulation protein D A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 Pfam PF03793 PASTA domain 584 637 2.3E-8 T 29-03-2018 IPR005543 PASTA domain A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 Gene3D G3DSA:3.40.710.10 218 563 6.5E-93 T 29-03-2018 A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 247 555 1.5E-82 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 SMART SM00740 580 638 4.0E-6 T 29-03-2018 IPR005543 PASTA domain A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 SUPERFAMILY SSF54184 584 637 2.75E-10 T 29-03-2018 A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 202 8.6E-20 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 SUPERFAMILY SSF56519 51 220 8.11E-42 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 SUPERFAMILY SSF56601 171 565 5.45E-97 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS21320 c68f077bdeff071e4691d56b2876e2d6 642 Gene3D G3DSA:3.90.1310.10 24 217 6.5E-44 T 29-03-2018 A616_RS18090 190fefc591574ef3a67f0ed0ea1b8576 187 Pfam PF02525 Flavodoxin-like fold 2 159 1.7E-41 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS18090 190fefc591574ef3a67f0ed0ea1b8576 187 SUPERFAMILY SSF52218 2 178 1.4E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS18090 190fefc591574ef3a67f0ed0ea1b8576 187 Gene3D G3DSA:3.40.50.360 1 182 1.7E-30 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS15450 9821a1bc9786828b127e7a7060ae19e5 196 SUPERFAMILY SSF53597 3 189 2.75E-25 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS15450 9821a1bc9786828b127e7a7060ae19e5 196 Pfam PF01872 RibD C-terminal domain 3 179 4.0E-20 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A616_RS15450 9821a1bc9786828b127e7a7060ae19e5 196 Gene3D G3DSA:3.40.430.10 2 188 5.3E-28 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS17910 f89e2cb72e2833bba0596da4f1477d61 470 Pfam PF01645 Conserved region in glutamate synthase 127 435 5.1E-59 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A616_RS17910 f89e2cb72e2833bba0596da4f1477d61 470 SUPERFAMILY SSF51395 84 462 1.56E-69 T 29-03-2018 A616_RS17910 f89e2cb72e2833bba0596da4f1477d61 470 PIRSF PIRSF006429 28 470 7.0E-103 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein A616_RS17910 f89e2cb72e2833bba0596da4f1477d61 470 Gene3D G3DSA:3.20.20.70 57 465 2.8E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 SUPERFAMILY SSF51419 30 299 1.25E-80 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS13450 0ef283f58048158a876ae68b958ba338 440 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 40.806 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 234 250 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A616_RS13450 0ef283f58048158a876ae68b958ba338 440 SUPERFAMILY SSF50621 272 433 2.3E-54 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 Gene3D G3DSA:3.20.20.10 38 281 6.2E-62 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS13450 0ef283f58048158a876ae68b958ba338 440 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 429 1.6E-153 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 1.3E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 1.3E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 1.3E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 1.3E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 1.3E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 Gene3D G3DSA:2.40.37.10 282 437 1.6E-44 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 297 1.1E-67 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 388 5.9E-18 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.5E-28 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.5E-28 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.5E-28 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13450 0ef283f58048158a876ae68b958ba338 440 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.5E-28 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 SUPERFAMILY SSF55785 5 102 2.47E-8 T 29-03-2018 IPR000014 PAS domain A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 SUPERFAMILY SSF46689 360 455 6.27E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Gene3D G3DSA:1.10.8.60 319 417 1.7E-20 T 29-03-2018 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Gene3D G3DSA:3.40.50.300 139 318 2.2E-27 T 29-03-2018 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 SMART SM00382 166 310 3.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Gene3D G3DSA:1.10.10.60 418 456 3.9E-12 T 29-03-2018 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 SMART SM00091 10 74 3.2E-6 T 29-03-2018 IPR000014 PAS domain A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Gene3D G3DSA:3.30.450.20 3 126 2.0E-9 T 29-03-2018 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 SUPERFAMILY SSF52540 145 388 1.14E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Pfam PF02954 Bacterial regulatory protein, Fis family 415 455 8.7E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 456 1.6E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 438 1.6E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Pfam PF00158 Sigma-54 interaction domain 146 313 6.4E-69 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS02065 bb430a617818201751eef3e28ab1cd32 456 Pfam PF00989 PAS fold 12 63 1.4E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS26675 43ef7e50951c29317696aecb43ef9419 513 Pfam PF15975 Flotillin 369 467 7.0E-15 T 29-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 A616_RS26675 43ef7e50951c29317696aecb43ef9419 513 SMART SM00244 26 204 1.3E-6 T 29-03-2018 IPR001107 Band 7 domain A616_RS26675 43ef7e50951c29317696aecb43ef9419 513 SUPERFAMILY SSF117892 69 211 2.09E-32 T 29-03-2018 IPR001107 Band 7 domain A616_RS26675 43ef7e50951c29317696aecb43ef9419 513 Pfam PF01145 SPFH domain / Band 7 family 30 231 8.9E-21 T 29-03-2018 IPR001107 Band 7 domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SMART SM00388 259 322 7.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Gene3D G3DSA:3.30.450.20 9 120 9.2E-14 T 29-03-2018 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SMART SM00091 132 198 0.22 T 29-03-2018 IPR000014 PAS domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SMART SM00091 13 79 6.1E-5 T 29-03-2018 IPR000014 PAS domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SUPERFAMILY SSF47384 252 319 2.16E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Gene3D G3DSA:3.30.450.20 136 248 6.5E-16 T 29-03-2018 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Pfam PF13426 PAS domain 144 243 4.2E-7 T 29-03-2018 IPR000014 PAS domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Pfam PF00989 PAS fold 15 119 3.3E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 468 6.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 147 251 7.6E-10 T 29-03-2018 IPR000014 PAS domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 119 8.4E-13 T 29-03-2018 IPR000014 PAS domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SMART SM00086 204 244 0.0064 T 29-03-2018 IPR001610 PAC motif A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SMART SM00086 84 125 530.0 T 29-03-2018 IPR001610 PAC motif A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Gene3D G3DSA:1.10.287.130 249 318 8.5E-14 T 29-03-2018 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SMART SM00387 364 470 6.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 319 2.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 Gene3D G3DSA:3.30.565.10 323 470 2.0E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SUPERFAMILY SSF55874 312 468 1.09E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SUPERFAMILY SSF55785 150 252 5.58E-15 T 29-03-2018 IPR000014 PAS domain A616_RS07760 0b5ab3216f489a0687756179a2465f46 470 SUPERFAMILY SSF55785 10 119 2.27E-13 T 29-03-2018 IPR000014 PAS domain A616_RS05130 af1051658ca036b75f6972e17a777e1f 162 Pfam PF04073 Aminoacyl-tRNA editing domain 28 145 6.8E-31 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS05130 af1051658ca036b75f6972e17a777e1f 162 Gene3D G3DSA:3.90.960.10 4 154 2.6E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS05130 af1051658ca036b75f6972e17a777e1f 162 SUPERFAMILY SSF55826 7 152 3.01E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SUPERFAMILY SSF49785 40 212 6.46E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Gene3D G3DSA:3.40.50.2300 717 922 3.0E-34 T 29-03-2018 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SUPERFAMILY SSF47384 439 518 5.69E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Pfam PF00512 His Kinase A (phospho-acceptor) domain 452 517 5.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SMART SM00388 451 519 1.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SUPERFAMILY SSF55874 911 1050 6.68E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SUPERFAMILY SSF55874 508 679 2.36E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SMART SM00387 565 675 8.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SMART SM00387 949 1053 9.5E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 1.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 653 1.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 672 1.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 954 1052 1.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 566 673 4.0E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SUPERFAMILY SSF52172 725 877 2.28E-34 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Pfam PF07695 7TM diverse intracellular signalling 229 411 3.3E-8 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Pfam PF00072 Response regulator receiver domain 728 837 3.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Gene3D G3DSA:2.60.120.260 62 233 4.2E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Pfam PF06580 Histidine kinase 855 935 1.9E-20 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Gene3D G3DSA:3.30.565.10 502 674 4.4E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Gene3D G3DSA:3.30.565.10 923 1054 4.9E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 SMART SM00448 726 839 6.6E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04410 8a6779b119eaf0bcd9cab2827ea3b2ce 1054 Gene3D G3DSA:1.10.287.130 441 501 4.4E-14 T 29-03-2018 A616_RS32180 92de357e3594a932355a34d695ef8c4c 159 Hamap MF_00984 Single-stranded DNA-binding protein. 1 106 36.518 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A616_RS32180 92de357e3594a932355a34d695ef8c4c 159 SUPERFAMILY SSF50249 1 159 7.54E-58 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS32180 92de357e3594a932355a34d695ef8c4c 159 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 159 2.9E-44 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A616_RS32180 92de357e3594a932355a34d695ef8c4c 159 Gene3D G3DSA:2.40.50.140 1 110 1.2E-43 T 29-03-2018 A616_RS32180 92de357e3594a932355a34d695ef8c4c 159 Pfam PF00436 Single-strand binding protein family 1 102 1.2E-38 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 SUPERFAMILY SSF51735 1 313 3.11E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 Gene3D G3DSA:3.40.50.720 1 174 9.3E-27 T 29-03-2018 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 Gene3D G3DSA:3.90.25.10 175 316 1.4E-39 T 29-03-2018 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 PRINTS PR01713 Nucleotide sugar epimerase signature 215 230 6.6E-12 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 PRINTS PR01713 Nucleotide sugar epimerase signature 30 46 6.6E-12 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 PRINTS PR01713 Nucleotide sugar epimerase signature 237 252 6.6E-12 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 PRINTS PR01713 Nucleotide sugar epimerase signature 276 293 6.6E-12 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS14045 663874782a0daacad4ef667e85fed0ea 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 243 8.9E-55 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 Gene3D G3DSA:3.40.50.280 2 127 6.6E-15 T 29-03-2018 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 Pfam PF04055 Radical SAM superfamily 187 349 2.5E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 SMART SM00729 182 394 8.9E-19 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 SUPERFAMILY SSF102114 176 386 7.32E-41 T 29-03-2018 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 Pfam PF02310 B12 binding domain 10 123 2.7E-20 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 SUPERFAMILY SSF52242 46 133 1.29E-9 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 Pfam PF13311 Protein of unknown function (DUF4080) 377 555 3.9E-44 T 29-03-2018 IPR025288 Domain of unknown function DUF4080 A616_RS09515 519197e16e9311fc875f592a4d8e2c20 592 Gene3D G3DSA:3.20.20.70 128 545 2.4E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Gene3D G3DSA:3.40.50.280 8 162 1.2E-27 T 29-03-2018 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Pfam PF01642 Methylmalonyl-CoA mutase 559 1077 5.0E-141 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 11 124 3.1E-17 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Pfam PF03308 ArgK protein 167 366 1.2E-38 T 29-03-2018 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Gene3D G3DSA:3.20.20.240 547 1079 7.4E-196 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 SUPERFAMILY SSF52540 147 456 1.91E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Gene3D G3DSA:3.40.50.300 195 404 9.6E-28 T 29-03-2018 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 SUPERFAMILY SSF52242 5 143 3.14E-41 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 559 1082 8.4E-113 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 SUPERFAMILY SSF51703 504 1079 4.19E-152 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Pfam PF02310 B12 binding domain 13 117 3.3E-13 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS30145 37f0c18090279b2c2641e4bba2876c8e 1083 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 11 1083 17.105 T 29-03-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 Pfam PF07690 Major Facilitator Superfamily 17 313 2.7E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 Gene3D G3DSA:1.20.1250.20 196 437 2.1E-27 T 29-03-2018 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 SUPERFAMILY SSF103473 7 394 2.09E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 PRINTS PR01035 Tetracycline resistance protein signature 137 159 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 PRINTS PR01035 Tetracycline resistance protein signature 17 33 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 PRINTS PR01035 Tetracycline resistance protein signature 280 301 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 PRINTS PR01035 Tetracycline resistance protein signature 165 185 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 77 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS21185 19705c4060248f4fe0f811f18d61af9d 457 Gene3D G3DSA:1.20.1250.20 3 195 1.5E-33 T 29-03-2018 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 Gene3D G3DSA:3.40.47.10 264 388 2.7E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 SUPERFAMILY SSF53901 269 389 2.66E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 1.7E-139 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 Pfam PF00108 Thiolase, N-terminal domain 4 261 4.7E-88 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 SUPERFAMILY SSF53901 3 268 4.51E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 Gene3D G3DSA:3.40.47.10 1 263 3.7E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 PIRSF PIRSF000429 1 392 1.5E-133 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS12385 dc14046f3a91d40387170e64aab530fb 393 Pfam PF02803 Thiolase, C-terminal domain 269 389 8.0E-47 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 Pfam PF07690 Major Facilitator Superfamily 25 415 1.4E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 6.4E-9 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 6.4E-9 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 6.4E-9 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 169 193 6.4E-9 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 6.4E-9 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 Gene3D G3DSA:1.20.1250.20 264 523 6.8E-24 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 505 1.4E-122 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 SUPERFAMILY SSF103473 209 425 1.05E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 SUPERFAMILY SSF103473 483 512 1.05E-25 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 Gene3D G3DSA:1.20.1250.20 15 206 1.1E-30 T 29-03-2018 A616_RS08050 51500ac8267e32e31bb28d60199425f4 524 SUPERFAMILY SSF103473 12 200 4.32E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS19785 47128ff2113c553ee996e287153eb048 331 Gene3D G3DSA:3.90.1640.10 2 204 1.5E-41 T 29-03-2018 A616_RS19785 47128ff2113c553ee996e287153eb048 331 SUPERFAMILY SSF64182 18 311 3.92E-63 T 29-03-2018 A616_RS19785 47128ff2113c553ee996e287153eb048 331 Pfam PF01368 DHH family 20 162 4.8E-13 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS19785 47128ff2113c553ee996e287153eb048 331 Pfam PF02272 DHHA1 domain 235 318 6.5E-13 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A616_RS07405 18d54f6519c20aa87e01eb06ab2d6432 410 Gene3D G3DSA:1.20.91.10 234 317 6.6E-5 T 29-03-2018 A616_RS07405 18d54f6519c20aa87e01eb06ab2d6432 410 Pfam PF00999 Sodium/hydrogen exchanger family 11 378 3.2E-55 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A616_RS31355 c7e91a4f3d22fd8e48e32f0dc0881d53 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 256 5.1E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31355 c7e91a4f3d22fd8e48e32f0dc0881d53 267 Gene3D G3DSA:1.10.3720.10 1 255 2.9E-39 T 29-03-2018 A616_RS31355 c7e91a4f3d22fd8e48e32f0dc0881d53 267 SUPERFAMILY SSF161098 5 267 1.7E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 SMART SM00387 261 353 5.4E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 SUPERFAMILY SSF55874 228 348 3.01E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 349 4.2E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 22 138 1.3E-10 T 29-03-2018 IPR000014 PAS domain A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 PIRSF PIRSF037432 13 350 1.7E-47 T 29-03-2018 IPR017203 Signal transduction histidine kinase, NreB GO:0000155|GO:0004673|GO:0005506|GO:0005524|GO:0005737|GO:0018106 A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 Pfam PF07730 Histidine kinase 156 221 1.9E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 Gene3D G3DSA:3.30.565.10 219 359 3.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 SUPERFAMILY SSF55785 22 114 3.66E-9 T 29-03-2018 IPR000014 PAS domain A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 Gene3D G3DSA:3.30.450.20 17 172 1.1E-12 T 29-03-2018 A616_RS15820 48cc8c5bf80bf2d61ce832d623942bcb 363 Pfam PF13188 PAS domain 22 57 4.8E-7 T 29-03-2018 IPR000014 PAS domain A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 Hamap MF_00104 Ribonuclease 3 [rnc]. 24 240 31.835 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 SMART SM00535 36 171 1.3E-57 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 Gene3D G3DSA:3.30.160.20 169 246 2.9E-21 T 29-03-2018 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 Gene3D G3DSA:1.10.1520.10 20 168 6.8E-45 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 SUPERFAMILY SSF54768 133 244 1.4E-23 T 29-03-2018 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 ProSitePatterns PS00517 Ribonuclease III family signature. 60 68 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 SMART SM00358 177 244 2.2E-21 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 Pfam PF00035 Double-stranded RNA binding motif 178 243 2.6E-17 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 24 242 2.3E-80 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 Pfam PF14622 Ribonuclease-III-like 34 164 7.8E-36 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS20270 03e2e617ecc4a3756c7c890be0fe93b2 246 SUPERFAMILY SSF69065 17 176 1.69E-52 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 Gene3D G3DSA:3.30.360.10 142 264 1.2E-64 T 29-03-2018 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 127 264 2.1E-64 T 29-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 288 3.2E-136 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 PIRSF PIRSF015689 1 293 9.9E-132 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 113 1.1E-11 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 SUPERFAMILY SSF55347 127 264 7.85E-59 T 29-03-2018 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 SMART SM00859 5 119 4.7E-7 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 295 124.927 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 Gene3D G3DSA:3.40.50.720 1 141 3.5E-15 T 29-03-2018 A616_RS16235 a4ae6f6c306fee7134609cab0bb86dd8 295 SUPERFAMILY SSF51735 1 151 3.37E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS11215 1a6025ab214300e90606556242df2d79 283 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 6 277 37.574 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A616_RS11215 1a6025ab214300e90606556242df2d79 283 Gene3D G3DSA:3.40.50.720 119 282 4.6E-35 T 29-03-2018 A616_RS11215 1a6025ab214300e90606556242df2d79 283 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 5.5E-32 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A616_RS11215 1a6025ab214300e90606556242df2d79 283 SUPERFAMILY SSF51735 106 278 1.32E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS11215 1a6025ab214300e90606556242df2d79 283 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 279 1.2E-87 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A616_RS11215 1a6025ab214300e90606556242df2d79 283 Gene3D G3DSA:3.40.50.10860 1 118 9.9E-48 T 29-03-2018 A616_RS11215 1a6025ab214300e90606556242df2d79 283 SUPERFAMILY SSF53223 2 105 4.72E-38 T 29-03-2018 A616_RS11215 1a6025ab214300e90606556242df2d79 283 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 121 171 1.3E-8 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 SUPERFAMILY SSF46689 169 219 3.12E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 Gene3D G3DSA:1.10.10.60 219 270 8.4E-15 T 29-03-2018 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 SUPERFAMILY SSF46689 221 269 9.86E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 Gene3D G3DSA:2.60.120.10 8 114 4.1E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 264 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 Pfam PF12833 Helix-turn-helix domain 191 268 4.8E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 252 2.7E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 268 2.7E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 Gene3D G3DSA:1.10.10.60 159 218 2.5E-15 T 29-03-2018 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 SUPERFAMILY SSF51215 35 140 6.8E-9 T 29-03-2018 A616_RS08215 641f720b7f925a6e823cf8430cca9800 270 SMART SM00342 185 268 5.7E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS32080 204ac571861d68580e14e18f84407175 306 PIRSF PIRSF016838 1 305 1.3E-21 T 29-03-2018 IPR028349 Protein PafC A616_RS32080 204ac571861d68580e14e18f84407175 306 Pfam PF08279 HTH domain 5 59 1.1E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS32080 204ac571861d68580e14e18f84407175 306 Gene3D G3DSA:1.10.10.10 1 64 2.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS32080 204ac571861d68580e14e18f84407175 306 SMART SM00420 5 51 0.009 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS32080 204ac571861d68580e14e18f84407175 306 Pfam PF13280 WYL domain 133 301 2.7E-33 T 29-03-2018 IPR026881 WYL domain A616_RS32080 204ac571861d68580e14e18f84407175 306 SUPERFAMILY SSF46785 2 62 6.57E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 SUPERFAMILY SSF46785 4 73 3.61E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 SMART SM01134 72 233 6.5E-69 T 29-03-2018 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 Gene3D G3DSA:1.10.10.10 1 64 1.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 SUPERFAMILY SSF100950 74 233 1.15E-32 T 29-03-2018 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 Gene3D G3DSA:3.40.50.1360 73 239 1.4E-38 T 29-03-2018 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 Pfam PF00455 DeoR C terminal sensor domain 74 232 1.3E-50 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 4.7E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 SMART SM00420 6 58 1.1E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.1E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS23720 96fcecd8faf272675ebae583ae5a1d67 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.1E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS01860 387f5fc16e42f131ede7b77d15c7b75c 183 SUPERFAMILY SSF53597 4 178 6.15E-29 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS01860 387f5fc16e42f131ede7b77d15c7b75c 183 Pfam PF01872 RibD C-terminal domain 4 174 1.1E-14 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A616_RS01860 387f5fc16e42f131ede7b77d15c7b75c 183 Gene3D G3DSA:3.40.430.10 3 179 1.7E-30 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS10985 a44f072a657d92cfafad357d3fab7e5f 267 SUPERFAMILY SSF53850 42 266 2.08E-32 T 29-03-2018 A616_RS10985 a44f072a657d92cfafad357d3fab7e5f 267 Gene3D G3DSA:3.40.190.10 43 148 6.8E-14 T 29-03-2018 A616_RS10985 a44f072a657d92cfafad357d3fab7e5f 267 Pfam PF13531 Bacterial extracellular solute-binding protein 45 266 4.1E-29 T 29-03-2018 A616_RS10985 a44f072a657d92cfafad357d3fab7e5f 267 Gene3D G3DSA:3.40.190.10 149 264 1.2E-10 T 29-03-2018 A616_RS11525 d006b01bfc69e7a84680622a15e8626d 62 Pfam PF13783 Domain of unknown function (DUF4177) 2 60 3.1E-18 T 29-03-2018 IPR025234 Protein of unknown function DUF4177 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-14 T 29-03-2018 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.422 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 Gene3D G3DSA:3.30.1550.10 3 71 3.7E-36 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal A616_RS01320 5d8e20c3d707043e00907881589da98f 141 SMART SM00649 9 140 7.4E-85 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.1E-63 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 Gene3D G3DSA:1.10.10.250 72 140 5.1E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 6.1E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal A616_RS01320 5d8e20c3d707043e00907881589da98f 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 SUPERFAMILY SSF46906 67 140 2.88E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A616_RS01320 5d8e20c3d707043e00907881589da98f 141 SUPERFAMILY SSF54747 3 72 3.01E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal A616_RS01320 5d8e20c3d707043e00907881589da98f 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 8.4E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A616_RS24940 2c4e0fd15f542a58a2950016b3549d6a 245 SUPERFAMILY SSF102588 2 200 5.1E-50 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24940 2c4e0fd15f542a58a2950016b3549d6a 245 Gene3D G3DSA:3.40.50.10320 1 225 4.8E-50 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24940 2c4e0fd15f542a58a2950016b3549d6a 245 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 134 2.9E-30 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A616_RS00955 76e7bd3eda64309665d2772b2da9bfa7 495 SUPERFAMILY SSF52540 102 422 1.4E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00955 76e7bd3eda64309665d2772b2da9bfa7 495 Pfam PF00437 Type II/IV secretion system protein 119 362 1.2E-46 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A616_RS00955 76e7bd3eda64309665d2772b2da9bfa7 495 Gene3D G3DSA:3.40.50.300 249 487 5.8E-12 T 29-03-2018 A616_RS00955 76e7bd3eda64309665d2772b2da9bfa7 495 Gene3D G3DSA:3.30.450.90 113 218 4.9E-24 T 29-03-2018 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 Gene3D G3DSA:3.30.565.10 300 459 3.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 459 4.1E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 304 3.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 SMART SM00304 178 230 6.5E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 SUPERFAMILY SSF55874 295 458 2.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 SUPERFAMILY SSF47384 221 305 1.59E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 SMART SM00387 351 459 2.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 SMART SM00388 238 305 3.5E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 9.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 9.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 9.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 9.0E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08485 e8ccffcb30b82d0b949021db087a373d 459 Gene3D G3DSA:1.10.287.130 221 299 9.1E-13 T 29-03-2018 A616_RS29815 e2b4bdc732d0d63829e2d2e23d34837b 338 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 67 330 3.9E-79 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 A616_RS29815 e2b4bdc732d0d63829e2d2e23d34837b 338 Pfam PF08486 Stage II sporulation protein 63 167 1.3E-24 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal A616_RS29815 e2b4bdc732d0d63829e2d2e23d34837b 338 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 6 330 4.5E-114 T 29-03-2018 IPR014225 Sporulation stage II, protein D firmicutes A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 SMART SM00436 124 214 3.5E-30 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 731 1.6E-178 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 383 399 1.6E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 184 202 1.6E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 1.6E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 1.6E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 516 530 1.6E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 Pfam PF01751 Toprim domain 3 132 1.8E-11 T 29-03-2018 IPR006171 TOPRIM domain A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 SMART SM00437 259 553 1.1E-68 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 SUPERFAMILY SSF56712 2 604 9.29E-169 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 296 311 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 Gene3D G3DSA:3.40.50.140 2 152 4.2E-38 T 29-03-2018 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 Gene3D G3DSA:1.10.460.10 157 338 1.3E-39 T 29-03-2018 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 Gene3D G3DSA:2.70.20.10 346 475 1.3E-24 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 Pfam PF01131 DNA topoisomerase 151 592 8.4E-118 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 Gene3D G3DSA:1.10.460.10 476 658 2.2E-28 T 29-03-2018 A616_RS21110 f90279d5fab8392ce627ff974e02c247 742 SMART SM00493 2 124 8.6E-13 T 29-03-2018 IPR006171 TOPRIM domain A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 Gene3D G3DSA:3.40.1160.10 1 316 4.4E-56 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PIRSF PIRSF000723 1 316 3.1E-127 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 TIGRFAM TIGR00746 arcC: carbamate kinase 4 316 2.0E-110 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 271 286 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 162 181 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 185 203 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 PRINTS PR01469 Bacterial carbamate kinase signature 216 231 6.2E-60 T 29-03-2018 A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 SUPERFAMILY SSF53633 3 315 2.62E-77 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS24870 a68096016b603a37a60a180661bbb4bb 316 Pfam PF00696 Amino acid kinase family 3 298 1.0E-31 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 349 357 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 SUPERFAMILY SSF56634 8 493 6.8E-196 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 SMART SM01060 17 408 4.2E-249 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 Pfam PF06628 Catalase-related immune-responsive 430 492 2.9E-20 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PRINTS PR00067 Catalase signature 119 136 7.1E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PRINTS PR00067 Catalase signature 336 362 7.1E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PRINTS PR00067 Catalase signature 304 331 7.1E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PRINTS PR00067 Catalase signature 30 53 7.1E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PRINTS PR00067 Catalase signature 138 156 7.1E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PRINTS PR00067 Catalase signature 98 116 7.1E-69 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 PIRSF PIRSF038928 4 497 3.5E-180 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 ProSitePatterns PS00438 Catalase proximal active site signature. 53 69 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 Gene3D G3DSA:2.40.180.10 1 373 4.5E-158 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS17740 422216f16acb6b818eeb465bd834cd40 529 Pfam PF00199 Catalase 17 404 1.4E-171 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 SUPERFAMILY SSF52172 4 190 1.99E-45 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 SMART SM00382 166 309 1.3E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Pfam PF02954 Bacterial regulatory protein, Fis family 415 455 3.4E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Gene3D G3DSA:3.40.50.2300 2 148 1.6E-37 T 29-03-2018 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Gene3D G3DSA:1.10.10.60 375 458 5.4E-14 T 29-03-2018 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Pfam PF00072 Response regulator receiver domain 7 114 3.6E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 458 1.3E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 438 1.3E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 SUPERFAMILY SSF46689 358 457 7.89E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 SUPERFAMILY SSF52540 146 386 6.71E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Gene3D G3DSA:3.40.50.300 149 318 7.1E-21 T 29-03-2018 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 SMART SM00448 5 116 6.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Pfam PF00158 Sigma-54 interaction domain 146 312 3.6E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS26575 6d94c4fc58f85151d744a03b786e4f43 459 Gene3D G3DSA:1.10.8.60 319 374 1.0E-19 T 29-03-2018 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 SMART SM00359 282 357 4.4E-9 T 29-03-2018 IPR002478 PUA domain GO:0003723 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 Hamap MF_00456 Glutamate 5-kinase [proB]. 6 261 34.774 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 Pfam PF00696 Amino acid kinase family 7 234 1.6E-42 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 PRINTS PR00474 Glutamate 5-kinase family signature 43 57 9.6E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 PRINTS PR00474 Glutamate 5-kinase family signature 149 176 9.6E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 PRINTS PR00474 Glutamate 5-kinase family signature 209 229 9.6E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 PRINTS PR00474 Glutamate 5-kinase family signature 117 138 9.6E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 PRINTS PR00474 Glutamate 5-kinase family signature 77 105 9.6E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 SUPERFAMILY SSF53633 7 255 4.45E-62 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 SUPERFAMILY SSF88697 281 360 4.04E-11 T 29-03-2018 IPR015947 PUA-like domain A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 ProSitePatterns PS00902 Glutamate 5-kinase signature. 207 224 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 Gene3D G3DSA:3.40.1160.10 1 263 6.6E-57 T 29-03-2018 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 Gene3D G3DSA:2.30.130.10 280 363 5.8E-14 T 29-03-2018 IPR002478 PUA domain GO:0003723 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 TIGRFAM TIGR01027 proB: glutamate 5-kinase 7 347 1.8E-117 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 Pfam PF01472 PUA domain 282 341 1.4E-12 T 29-03-2018 IPR002478 PUA domain GO:0003723 A616_RS27000 0b5d54d13e5f47963a28d191656c42d0 366 PIRSF PIRSF000729 1 366 7.9E-119 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A616_RS09920 920aaf726a451bdd021886f69519a1fd 280 SUPERFAMILY SSF161098 8 280 7.76E-76 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09920 920aaf726a451bdd021886f69519a1fd 280 Gene3D G3DSA:1.10.3720.10 1 268 2.3E-47 T 29-03-2018 A616_RS09920 920aaf726a451bdd021886f69519a1fd 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 274 4.8E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 SUPERFAMILY SSF46894 782 851 1.09E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 SMART SM00421 792 849 5.9E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 Gene3D G3DSA:3.40.50.300 25 221 2.3E-7 T 29-03-2018 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 SUPERFAMILY SSF52540 15 235 7.91E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 Gene3D G3DSA:1.10.10.10 782 855 1.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 SUPERFAMILY SSF48452 580 774 1.71E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 Gene3D G3DSA:1.25.40.10 315 780 6.1E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 795 809 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 825 837 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 809 825 7.7E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS28700 b0022c30d948238f3ad0905749ac9704 856 Pfam PF00196 Bacterial regulatory proteins, luxR family 794 847 2.6E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 SMART SM00304 191 243 2.1E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 Pfam PF00672 HAMP domain 191 239 2.1E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 473 6.5E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 Gene3D G3DSA:1.10.287.130 234 314 3.8E-18 T 29-03-2018 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 SMART SM00388 251 318 2.8E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 Gene3D G3DSA:3.30.450.20 34 164 6.2E-17 T 29-03-2018 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 SUPERFAMILY SSF55874 307 475 1.13E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 Gene3D G3DSA:3.30.565.10 322 476 6.2E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 SUPERFAMILY SSF158472 191 240 3.27E-10 T 29-03-2018 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 SMART SM00387 364 475 3.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 SUPERFAMILY SSF47384 234 319 6.67E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05295 9e8c3b9f8940b491f95bf3e4962ffe34 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 317 1.9E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03200 558f8446a3ea44eb94f30080639a049f 512 Pfam PF01433 Peptidase family M1 domain 270 491 6.8E-22 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A616_RS03200 558f8446a3ea44eb94f30080639a049f 512 SUPERFAMILY SSF55486 271 493 2.78E-37 T 29-03-2018 A616_RS03200 558f8446a3ea44eb94f30080639a049f 512 Gene3D G3DSA:2.60.40.1730 44 241 1.6E-5 T 29-03-2018 A616_RS03200 558f8446a3ea44eb94f30080639a049f 512 Gene3D G3DSA:1.10.390.10 332 494 8.9E-25 T 29-03-2018 A616_RS21180 1a3c2d789ba7835bdb106b9660cc748f 157 Pfam PF00293 NUDIX domain 29 87 1.6E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS21180 1a3c2d789ba7835bdb106b9660cc748f 157 SUPERFAMILY SSF55811 4 88 5.15E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS21180 1a3c2d789ba7835bdb106b9660cc748f 157 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS21180 1a3c2d789ba7835bdb106b9660cc748f 157 Gene3D G3DSA:3.90.79.10 1 156 8.9E-19 T 29-03-2018 A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 PIRSF PIRSF004640 1 358 3.7E-148 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 Gene3D G3DSA:3.20.20.120 13 200 1.1E-17 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 SUPERFAMILY SSF51604 40 139 2.47E-7 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 2 352 33.546 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 4 347 1.1E-125 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 Pfam PF04551 GcpE protein 7 348 3.7E-138 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A616_RS19835 287dc66c0824d90fde8daee1cb1e0ad8 360 SUPERFAMILY SSF56014 262 345 4.3E-12 T 29-03-2018 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 412 53.791 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.9E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 SMART SM00382 108 259 5.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 SUPERFAMILY SSF52540 59 402 1.7E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 108 307 2.0E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 SMART SM01086 314 408 2.7E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 SUPERFAMILY SSF57716 11 46 2.14E-11 T 29-03-2018 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 Gene3D G3DSA:3.40.50.300 53 312 1.5E-68 T 29-03-2018 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 1 408 3.1E-209 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 314 392 3.1E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 SMART SM00994 10 49 1.3E-23 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A616_RS10300 1806bcf07c1d3fc626758129aae344cc 421 Gene3D G3DSA:1.10.8.60 314 406 1.2E-35 T 29-03-2018 A616_RS29770 462d54eb45c679c6a52452be5dc6dc5b 245 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 4 241 59.821 T 29-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 A616_RS29770 462d54eb45c679c6a52452be5dc6dc5b 245 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 61 226 1.9E-65 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A616_RS29770 462d54eb45c679c6a52452be5dc6dc5b 245 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 60 232 8.6E-62 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A616_RS00555 ddb7450e0803d839b655bc930357e637 60 Pfam PF10764 Inhibitor of sigma-G Gin 8 52 2.1E-20 T 29-03-2018 IPR019700 Anti-sigma-G factor Gin A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 Gene3D G3DSA:3.10.580.10 194 340 4.4E-31 T 29-03-2018 A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 SUPERFAMILY SSF54631 205 345 4.8E-32 T 29-03-2018 A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 SMART SM01091 351 428 1.3E-13 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 Pfam PF00571 CBS domain 285 334 1.5E-7 T 29-03-2018 IPR000644 CBS domain A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 Pfam PF00571 CBS domain 217 264 0.0011 T 29-03-2018 IPR000644 CBS domain A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 SMART SM00116 224 274 22.0 T 29-03-2018 IPR000644 CBS domain A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 SMART SM00116 286 334 0.11 T 29-03-2018 IPR000644 CBS domain A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 Gene3D G3DSA:3.30.465.10 341 428 2.0E-16 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 SUPERFAMILY SSF56176 352 430 1.45E-14 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 Pfam PF03471 Transporter associated domain 354 426 2.3E-14 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS01855 1a211ff58163677ed77db281a112ff6a 439 Pfam PF01595 Domain of unknown function DUF21 7 200 3.6E-48 T 29-03-2018 IPR002550 Domain of unknown function DUF21 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PIRSF PIRSF000350 2 459 2.7E-94 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.0E-78 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 SUPERFAMILY SSF55424 344 467 1.03E-43 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 3.5E-38 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Gene3D G3DSA:1.10.287.990 54 109 1.3E-26 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.3E-43 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.3E-43 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.3E-43 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.3E-43 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.3E-43 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 1.1E-176 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Gene3D G3DSA:3.40.50.720 7 53 0.007 T 29-03-2018 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Gene3D G3DSA:3.30.390.30 361 469 7.1E-43 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Gene3D G3DSA:3.50.50.60 272 360 9.8E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 329 7.5E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 SUPERFAMILY SSF51905 7 339 6.48E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS19010 c4fbc7efc918a903eb6eff5c09ce6555 469 Gene3D G3DSA:3.50.50.60 121 253 1.9E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS12975 cea52814116452a65ca43b157e400299 309 SUPERFAMILY SSF52151 6 299 8.63E-41 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS12975 cea52814116452a65ca43b157e400299 309 Gene3D G3DSA:3.40.1090.10 5 287 6.8E-45 T 29-03-2018 A616_RS12975 cea52814116452a65ca43b157e400299 309 Pfam PF01734 Patatin-like phospholipase 6 195 1.4E-26 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 481 8.1E-86 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 104 126 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 Gene3D G3DSA:3.40.190.10 191 329 1.2E-38 T 29-03-2018 A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 Gene3D G3DSA:3.90.76.10 80 190 2.0E-30 T 29-03-2018 A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 PIRSF PIRSF002741 11 558 2.1E-123 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 SUPERFAMILY SSF53850 48 552 3.68E-133 T 29-03-2018 A616_RS24065 d491c8e4d6f53cab84e2e588aff6bb10 558 Gene3D G3DSA:3.10.105.10 330 530 3.2E-58 T 29-03-2018 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 260 333 6.5E-26 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A616_RS00725 ae94638996f3bab8f26785838038dc84 492 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 406 457 7.1E-5 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A616_RS00725 ae94638996f3bab8f26785838038dc84 492 SUPERFAMILY SSF101386 372 467 7.66E-24 T 29-03-2018 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 Gene3D G3DSA:3.40.1010.10 6 124 1.1E-17 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 SUPERFAMILY SSF53790 7 262 4.22E-28 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 Gene3D G3DSA:1.10.287.1080 237 355 4.0E-39 T 29-03-2018 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 SUPERFAMILY SSF101386 238 339 5.96E-22 T 29-03-2018 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 Gene3D G3DSA:1.10.287.1080 374 492 1.1E-24 T 29-03-2018 A616_RS00725 ae94638996f3bab8f26785838038dc84 492 PIRSF PIRSF002845 4 492 2.9E-199 T 29-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted A616_RS00725 ae94638996f3bab8f26785838038dc84 492 TIGRFAM TIGR00444 mazG: MazG family protein 244 488 9.9E-95 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG A616_RS00725 ae94638996f3bab8f26785838038dc84 492 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 211 9.6E-23 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 6.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 6.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 Gene3D G3DSA:3.40.50.720 1 254 5.6E-52 T 29-03-2018 A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 SUPERFAMILY SSF51735 2 251 6.62E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 Pfam PF00106 short chain dehydrogenase 7 204 1.7E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15335 a7c05411b781c24983b4ba0975e8a965 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS13275 882cc4a306fa6986967bcdcac1a637eb 330 Pfam PF00676 Dehydrogenase E1 component 22 321 1.9E-96 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A616_RS13275 882cc4a306fa6986967bcdcac1a637eb 330 Gene3D G3DSA:3.40.50.970 1 330 8.9E-83 T 29-03-2018 A616_RS13275 882cc4a306fa6986967bcdcac1a637eb 330 SUPERFAMILY SSF52518 7 329 3.4E-102 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Pfam PF00672 HAMP domain 302 351 1.4E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 SUPERFAMILY SSF103190 129 192 9.42E-8 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Gene3D G3DSA:1.20.5.1040 10 46 0.011 T 29-03-2018 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 SMART SM00304 302 354 1.9E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Gene3D G3DSA:1.10.287.950 420 659 2.4E-53 T 29-03-2018 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 SMART SM00283 383 658 3.4E-78 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Gene3D G3DSA:3.30.450.20 47 194 5.3E-17 T 29-03-2018 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 SUPERFAMILY SSF58104 324 356 1.83E-71 T 29-03-2018 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 SUPERFAMILY SSF58104 389 657 1.83E-71 T 29-03-2018 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Pfam PF02743 Cache domain 42 264 9.0E-24 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 427 604 1.4E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS06970 38ec08406eaf6c723f066697aaaae191 659 Gene3D G3DSA:1.10.287.500 330 419 3.2E-5 T 29-03-2018 A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 Gene3D G3DSA:3.40.640.10 15 292 3.0E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 419 480 2.0E-12 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 Gene3D G3DSA:3.90.1150.10 304 404 5.8E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 SUPERFAMILY SSF53383 16 387 1.48E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 SUPERFAMILY SSF55904 346 489 7.72E-27 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 Gene3D G3DSA:3.90.100.10 405 490 1.6E-25 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS00560 95e413e4301fc612392618f59b4f03d9 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 16 310 1.0E-78 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A616_RS30505 422b099880430e366a90918e06785cf9 574 Pfam PF01740 STAS domain 439 539 8.2E-16 T 29-03-2018 IPR002645 STAS domain A616_RS30505 422b099880430e366a90918e06785cf9 574 SUPERFAMILY SSF52091 436 543 3.34E-18 T 29-03-2018 IPR002645 STAS domain A616_RS30505 422b099880430e366a90918e06785cf9 574 Pfam PF00916 Sulfate permease family 15 379 2.8E-95 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A616_RS30505 422b099880430e366a90918e06785cf9 574 TIGRFAM TIGR00815 sulP: sulfate permease 7 538 2.8E-118 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 A616_RS30505 422b099880430e366a90918e06785cf9 574 Gene3D G3DSA:3.30.750.24 430 550 3.3E-21 T 29-03-2018 IPR002645 STAS domain A616_RS02035 77361acfdbeaec7791c15c07abe4833b 334 Gene3D G3DSA:3.40.50.1980 53 169 8.3E-23 T 29-03-2018 A616_RS02035 77361acfdbeaec7791c15c07abe4833b 334 Gene3D G3DSA:3.40.50.1980 170 334 5.7E-32 T 29-03-2018 A616_RS02035 77361acfdbeaec7791c15c07abe4833b 334 SUPERFAMILY SSF53807 56 326 1.06E-61 T 29-03-2018 A616_RS02035 77361acfdbeaec7791c15c07abe4833b 334 Pfam PF01497 Periplasmic binding protein 113 305 1.6E-33 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 SUPERFAMILY SSF48498 92 204 7.69E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 Gene3D G3DSA:1.10.10.60 10 45 3.1E-14 T 29-03-2018 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 Gene3D G3DSA:1.10.260.40 46 76 2.9E-10 T 29-03-2018 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 Gene3D G3DSA:1.10.357.10 77 206 1.3E-10 T 29-03-2018 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 SUPERFAMILY SSF46689 13 91 9.75E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30290 7c6bd0cc332911821797bd5866f95275 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 3.1E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS30830 c2f0679d913ecaaa5b3b641f3d582aad 476 Gene3D G3DSA:3.40.50.2300 375 476 2.3E-19 T 29-03-2018 A616_RS30830 c2f0679d913ecaaa5b3b641f3d582aad 476 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 17 354 1.4E-175 T 29-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A616_RS30830 c2f0679d913ecaaa5b3b641f3d582aad 476 Pfam PF02378 Phosphotransferase system, EIIC 26 284 1.1E-20 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A616_RS30830 c2f0679d913ecaaa5b3b641f3d582aad 476 SUPERFAMILY SSF52794 386 474 3.61E-25 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A616_RS30830 c2f0679d913ecaaa5b3b641f3d582aad 476 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 389 473 5.2E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A616_RS07465 04e975f865aac94216c53d554992cdd1 667 Gene3D G3DSA:3.40.710.10 47 394 3.5E-72 T 29-03-2018 A616_RS07465 04e975f865aac94216c53d554992cdd1 667 ProSitePatterns PS00146 Beta-lactamase class-A active site. 105 120 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 A616_RS07465 04e975f865aac94216c53d554992cdd1 667 Pfam PF00395 S-layer homology domain 500 543 3.7E-6 T 29-03-2018 IPR001119 S-layer homology domain A616_RS07465 04e975f865aac94216c53d554992cdd1 667 SUPERFAMILY SSF56601 53 378 1.63E-76 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS07465 04e975f865aac94216c53d554992cdd1 667 Pfam PF00144 Beta-lactamase 57 377 5.1E-56 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS10880 6194cfbf4afc686988ee55be7e762a63 354 Pfam PF01966 HD domain 137 259 3.0E-17 T 29-03-2018 IPR006674 HD domain A616_RS10880 6194cfbf4afc686988ee55be7e762a63 354 Gene3D G3DSA:1.10.3210.10 51 305 2.6E-39 T 29-03-2018 A616_RS10880 6194cfbf4afc686988ee55be7e762a63 354 TIGRFAM TIGR00277 HDIG: HDIG domain 136 213 2.0E-8 T 29-03-2018 IPR006675 HDIG domain A616_RS10880 6194cfbf4afc686988ee55be7e762a63 354 SMART SM00471 133 269 2.2E-9 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS10880 6194cfbf4afc686988ee55be7e762a63 354 SUPERFAMILY SSF109604 119 297 1.84E-33 T 29-03-2018 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SMART SM00267 226 399 1.5E-45 T 29-03-2018 IPR000160 GGDEF domain A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Gene3D G3DSA:3.40.50.2300 112 241 6.1E-23 T 29-03-2018 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Pfam PF00990 Diguanylate cyclase, GGDEF domain 240 395 1.5E-38 T 29-03-2018 IPR000160 GGDEF domain A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SUPERFAMILY SSF47226 7 83 3.4E-7 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SUPERFAMILY SSF52172 411 538 1.42E-31 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Pfam PF01627 Hpt domain 13 62 5.4E-6 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Pfam PF00072 Response regulator receiver domain 114 224 1.0E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Pfam PF00072 Response regulator receiver domain 414 533 1.3E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Gene3D G3DSA:1.20.120.160 5 94 2.0E-7 T 29-03-2018 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Gene3D G3DSA:3.30.70.270 242 407 1.1E-44 T 29-03-2018 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SUPERFAMILY SSF52172 107 240 1.22E-26 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 240 398 1.2E-39 T 29-03-2018 IPR000160 GGDEF domain A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SMART SM00448 111 224 5.8E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SMART SM00448 412 532 1.2E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 SUPERFAMILY SSF55073 243 397 1.18E-41 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS27960 01e116daec1bd6caa520a96fb8e16313 540 Gene3D G3DSA:3.40.50.2300 408 539 4.6E-31 T 29-03-2018 A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 Gene3D G3DSA:1.20.1560.10 18 321 2.0E-39 T 29-03-2018 A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 Gene3D G3DSA:3.40.50.300 322 573 4.0E-80 T 29-03-2018 A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 Pfam PF00005 ABC transporter 349 498 5.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 SUPERFAMILY SSF52540 328 568 2.56E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 SUPERFAMILY SSF90123 19 328 2.22E-51 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 SMART SM00382 358 544 3.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20615 c7bc20b464542cc409af2af99e9fc9c6 578 Pfam PF00664 ABC transporter transmembrane region 96 284 1.8E-23 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 Gene3D G3DSA:1.10.357.10 59 193 5.6E-24 T 29-03-2018 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 6.3E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 Gene3D G3DSA:1.10.10.60 1 58 3.2E-17 T 29-03-2018 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 SUPERFAMILY SSF46689 2 81 9.48E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS17860 50594fc2c5ccd63e421d0151a36afd26 193 SUPERFAMILY SSF48498 78 192 3.82E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Gene3D G3DSA:3.90.320.10 1043 1262 2.3E-36 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 SUPERFAMILY SSF52540 10 185 2.13E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 SUPERFAMILY SSF52540 895 921 2.13E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 SUPERFAMILY SSF52540 342 507 2.13E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 SUPERFAMILY SSF52540 539 858 2.13E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Pfam PF13361 UvrD-like helicase C-terminal domain 480 917 2.4E-26 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1091 1261 1.3E-9 T 29-03-2018 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Gene3D G3DSA:3.40.50.300 481 653 5.8E-22 T 29-03-2018 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Gene3D G3DSA:1.10.486.10 654 807 9.4E-40 T 29-03-2018 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 12 1265 0.0 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 463 4.4E-79 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 10 1271 18.594 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 SUPERFAMILY SSF52980 1054 1253 1.5E-30 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Gene3D G3DSA:3.40.50.300 5 263 2.9E-30 T 29-03-2018 A616_RS27365 8d6124d2e78cf9265b85d56fdf71a1e8 1277 Gene3D G3DSA:3.40.50.300 297 476 1.9E-26 T 29-03-2018 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 11 54 5.0E-10 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 15.14 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 Pfam PF02609 Exonuclease VII small subunit 14 64 7.7E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 SUPERFAMILY SSF116842 7 72 3.4E-21 T 29-03-2018 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 PIRSF PIRSF006488 2 83 4.6E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 14 69 1.5E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A616_RS13135 8938cb8449d343cc64ea5817f6544800 83 Gene3D G3DSA:1.10.287.1040 11 76 3.0E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 Gene3D G3DSA:1.10.10.60 19 54 1.6E-16 T 29-03-2018 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 Gene3D G3DSA:1.10.357.10 81 210 1.2E-15 T 29-03-2018 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 SUPERFAMILY SSF48498 96 207 1.47E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 SUPERFAMILY SSF46689 19 87 6.98E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 Gene3D G3DSA:1.10.260.40 55 80 3.0E-8 T 29-03-2018 A616_RS30150 d36def2f67c674307bd569b29fd8a236 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 8.0E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24945 1a0f3b8904b474a36c9763aa6ba5edb6 338 SUPERFAMILY SSF53067 141 329 3.97E-49 T 29-03-2018 A616_RS24945 1a0f3b8904b474a36c9763aa6ba5edb6 338 Gene3D G3DSA:3.30.420.40 8 123 7.3E-20 T 29-03-2018 A616_RS24945 1a0f3b8904b474a36c9763aa6ba5edb6 338 SUPERFAMILY SSF53067 8 138 3.89E-13 T 29-03-2018 A616_RS24945 1a0f3b8904b474a36c9763aa6ba5edb6 338 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 11 322 5.5E-38 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A616_RS24945 1a0f3b8904b474a36c9763aa6ba5edb6 338 Gene3D G3DSA:3.30.420.40 142 305 2.9E-46 T 29-03-2018 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 2 170 2.6E-15 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 SMART SM00304 205 258 1.1E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 Gene3D G3DSA:1.20.120.570 31 139 0.037 T 29-03-2018 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 Gene3D G3DSA:1.10.287.950 167 313 2.4E-6 T 29-03-2018 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 Gene3D G3DSA:1.10.287.950 314 563 1.1E-53 T 29-03-2018 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 Pfam PF00672 HAMP domain 205 255 2.0E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 SUPERFAMILY SSF58104 293 561 2.88E-69 T 29-03-2018 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 SUPERFAMILY SSF58104 229 260 2.88E-69 T 29-03-2018 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 20 3.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 443 3.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 412 3.3E-24 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 SMART SM00283 287 562 9.5E-74 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS12740 ed7e64509afcd347174dbaea23c79c8c 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 515 6.7E-46 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 455 6.0E-136 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 Pfam PF04552 Sigma-54, DNA binding domain 298 456 5.2E-63 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 Gene3D G3DSA:1.10.10.10 303 395 4.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 436 443 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 50 2.5E-15 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 PIRSF PIRSF000774 1 457 2.3E-152 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 PRINTS PR00045 Sigma-54 factor signature 357 369 2.7E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 PRINTS PR00045 Sigma-54 factor signature 431 449 2.7E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 PRINTS PR00045 Sigma-54 factor signature 169 186 2.7E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 PRINTS PR00045 Sigma-54 factor signature 373 384 2.7E-30 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS29065 aa985fffc17b59831c7ba5ef30d68280 457 Pfam PF04963 Sigma-54 factor, core binding domain 98 283 4.6E-57 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 197 414 2.8E-33 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 Gene3D G3DSA:3.90.1170.30 56 104 5.5E-4 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 SUPERFAMILY SSF111369 129 165 4.32E-5 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 SUPERFAMILY SSF111369 205 276 4.32E-5 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 Gene3D G3DSA:1.20.58.60 105 141 0.11 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 Gene3D G3DSA:2.40.50.100 218 414 3.8E-7 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 Pfam PF13533 Biotin-lipoyl like 66 106 1.1E-7 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 SUPERFAMILY SSF111369 63 118 3.01E-6 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 Pfam PF13437 HlyD family secretion protein 222 331 1.2E-16 T 29-03-2018 A616_RS05085 47a561c06aa633606774c5460cc26ec0 425 Gene3D G3DSA:1.10.287.470 142 186 3.0E-9 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 15 192 1.22E-41 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.40.50.980 2695 2838 8.8E-37 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:1.10.1200.10 984 1047 3.1E-21 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 3312 3561 5.67E-33 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:1.10.1200.10 3052 3112 2.7E-22 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:2.30.38.10 2851 2933 7.8E-26 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:2.30.38.10 781 863 7.2E-25 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00501 AMP-binding enzyme 1513 1906 2.3E-109 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00501 AMP-binding enzyme 474 870 1.1E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00501 AMP-binding enzyme 2551 2940 4.5E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2572 2963 2.1E-133 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 494 894 2.2E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1534 1930 1.3E-131 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF56801 433 991 3.53E-159 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 2093 2284 1.11E-42 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 2270 2537 7.67E-59 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1652 1663 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3072 3087 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.559.10 3113 3329 1.6E-28 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.559.10 3 215 1.5E-32 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.559.10 1048 1249 3.3E-39 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.559.10 2083 2290 2.1E-42 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SMART SM01294 3049 3112 0.0067 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2038 2053 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF47336 3040 3112 1.57E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.40.50.980 465 617 7.5E-51 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.40.50.980 1505 1657 5.6E-49 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.40.50.980 2542 2694 2.3E-50 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2690 2701 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.300.30 865 983 5.7E-40 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.300.30 2935 3051 1.5E-36 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.30.300.30 1901 2019 1.4E-36 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 1234 1476 1.22E-60 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3432 3585 4.4E-46 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF56801 1471 2027 2.22E-165 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:1.10.1200.10 2020 2082 9.4E-21 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 193 437 9.56E-53 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF47336 970 1044 3.53E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00668 Condensation domain 2096 2531 1.3E-122 T 29-03-2018 IPR001242 Condensation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00668 Condensation domain 9 453 1.5E-119 T 29-03-2018 IPR001242 Condensation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00668 Condensation domain 1059 1493 7.2E-130 T 29-03-2018 IPR001242 Condensation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00668 Condensation domain 3125 3577 3.2E-106 T 29-03-2018 IPR001242 Condensation domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 1060 1248 3.34E-43 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF13193 AMP-binding enzyme C-terminal domain 2948 3021 2.3E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF13193 AMP-binding enzyme C-terminal domain 1914 1987 9.2E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF13193 AMP-binding enzyme C-terminal domain 878 951 7.3E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF52777 3130 3303 4.34E-37 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF56801 2509 3061 1.23E-167 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:2.30.38.10 1816 1896 3.5E-27 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SUPERFAMILY SSF47336 2006 2080 4.03E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00550 Phosphopantetheine attachment site 3051 3112 6.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00550 Phosphopantetheine attachment site 2016 2079 2.7E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Pfam PF00550 Phosphopantetheine attachment site 980 1043 6.0E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SMART SM00823 Phosphopantetheine attachment site 2014 2083 0.0094 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SMART SM00823 Phosphopantetheine attachment site 3048 3116 0.0012 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 SMART SM00823 Phosphopantetheine attachment site 978 1047 8.1E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.40.50.980 618 776 1.1E-27 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 Gene3D G3DSA:3.40.50.980 1658 1814 2.2E-34 T 29-03-2018 A616_RS15665 fb3eb1b5a6436c1cdee44e2498c65415 3589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1002 1017 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 Gene3D G3DSA:3.20.20.120 124 357 3.5E-65 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 SMART SM00922 141 240 5.7E-28 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 SUPERFAMILY SSF51604 126 355 1.83E-67 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 Pfam PF13378 Enolase C-terminal domain-like 143 355 7.5E-51 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 SUPERFAMILY SSF54826 1 125 6.93E-34 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 Gene3D G3DSA:3.30.390.10 1 123 2.9E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS01080 bc043a31b0e7db11217e875ac73af5a6 364 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 124 4.7E-24 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A616_RS04405 2fc7f13bdaa0994b749d495019b2ea34 382 Pfam PF12698 ABC-2 family transporter protein 19 370 1.0E-43 T 29-03-2018 A616_RS04405 2fc7f13bdaa0994b749d495019b2ea34 382 Gene3D G3DSA:3.40.1710.10 39 199 2.7E-13 T 29-03-2018 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Pfam PF01568 Molydopterin dinucleotide binding domain 565 668 3.5E-16 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Gene3D G3DSA:3.40.50.740 68 166 3.5E-18 T 29-03-2018 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 62 3.4E-15 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Gene3D G3DSA:3.40.50.740 263 522 2.7E-48 T 29-03-2018 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 417 434 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 SUPERFAMILY SSF53706 11 556 3.27E-166 T 29-03-2018 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Pfam PF00384 Molybdopterin oxidoreductase 66 472 1.0E-63 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Gene3D G3DSA:2.40.40.20 549 680 1.7E-22 T 29-03-2018 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 SUPERFAMILY SSF50692 526 678 4.77E-27 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Gene3D G3DSA:3.40.228.10 167 262 4.5E-21 T 29-03-2018 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 SMART SM00926 8 63 2.0E-16 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS12260 1bf0f7e0ec429bb6a2a589346e064ca0 680 Gene3D G3DSA:2.20.25.90 1 67 2.1E-18 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82714 183 262 1.01E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82714 710 792 1.16E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Gene3D G3DSA:3.30.70.1430 40 141 3.0E-26 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 617 631 2.0E-35 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Gene3D G3DSA:1.20.1640.10 264 490 2.2E-42 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Gene3D G3DSA:1.20.1640.10 807 1027 3.7E-44 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Gene3D G3DSA:3.30.2090.10 179 263 5.1E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Gene3D G3DSA:3.30.2090.10 707 795 2.6E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82693 560 659 4.88E-15 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Pfam PF00873 AcrB/AcrD/AcrF family 4 1009 1.6E-251 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82866 287 486 3.53E-41 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 Gene3D G3DSA:3.30.70.1430 561 660 6.7E-20 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82866 797 1016 8.89E-52 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82693 136 180 6.8E-21 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82693 265 321 6.8E-21 T 29-03-2018 A616_RS18610 df17c6d3767c18939841d0b35566be9b 1045 SUPERFAMILY SSF82693 41 134 2.44E-25 T 29-03-2018 A616_RS23620 78fdfc75c096159a5b7d0f571244b95e 278 Gene3D G3DSA:3.60.15.10 2 269 3.0E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS23620 78fdfc75c096159a5b7d0f571244b95e 278 Pfam PF00753 Metallo-beta-lactamase superfamily 21 79 7.9E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS23620 78fdfc75c096159a5b7d0f571244b95e 278 SUPERFAMILY SSF56281 4 253 1.19E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS23620 78fdfc75c096159a5b7d0f571244b95e 278 SMART SM00849 21 195 0.0063 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS09000 693e9292289ebe1300c4cc24f3b0eed3 156 Gene3D G3DSA:1.20.120.450 1 156 1.5E-28 T 29-03-2018 A616_RS09000 693e9292289ebe1300c4cc24f3b0eed3 156 SUPERFAMILY SSF109854 5 150 3.51E-31 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS09000 693e9292289ebe1300c4cc24f3b0eed3 156 Pfam PF12867 DinB superfamily 10 144 1.9E-17 T 29-03-2018 IPR024775 DinB-like domain A616_RS19435 471418469afce87dc580e4f4313e5abf 430 Gene3D G3DSA:3.40.50.300 160 407 3.4E-34 T 29-03-2018 A616_RS19435 471418469afce87dc580e4f4313e5abf 430 Pfam PF16360 GTP-binding GTPase Middle Region 117 195 6.3E-31 T 29-03-2018 IPR032305 GTP-binding protein, middle domain A616_RS19435 471418469afce87dc580e4f4313e5abf 430 Hamap MF_00900 GTPase HflX [hflX]. 30 388 46.755 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 A616_RS19435 471418469afce87dc580e4f4313e5abf 430 Pfam PF01926 50S ribosome-binding GTPase 202 321 3.0E-20 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS19435 471418469afce87dc580e4f4313e5abf 430 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 357 1.1E-145 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 A616_RS19435 471418469afce87dc580e4f4313e5abf 430 Pfam PF13167 GTP-binding GTPase N-terminal 29 115 2.8E-34 T 29-03-2018 IPR025121 GTPase HflX, N-terminal A616_RS19435 471418469afce87dc580e4f4313e5abf 430 SUPERFAMILY SSF52540 200 365 2.05E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19435 471418469afce87dc580e4f4313e5abf 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 203 223 2.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS19435 471418469afce87dc580e4f4313e5abf 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 270 288 2.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS19435 471418469afce87dc580e4f4313e5abf 430 PIRSF PIRSF006809 2 414 4.9E-150 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 284 375 4.9E-14 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 Gene3D G3DSA:3.40.710.10 25 283 2.8E-50 T 29-03-2018 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 SUPERFAMILY SSF56601 4 284 2.36E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 SMART SM00936 284 376 5.8E-16 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 40 263 3.5E-82 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 1.3E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 120 137 1.3E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 147 160 1.3E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 SUPERFAMILY SSF69189 284 378 7.26E-14 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS13395 8ae7bb20e1ac8381078edcde88b63c00 394 Gene3D G3DSA:2.60.410.10 286 376 2.5E-15 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS31810 1f62c7b7ee821b63a67c7311e9b635c2 363 Gene3D G3DSA:3.40.50.10490 195 337 1.1E-29 T 29-03-2018 A616_RS31810 1f62c7b7ee821b63a67c7311e9b635c2 363 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 28 353 3.5E-71 T 29-03-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A616_RS31810 1f62c7b7ee821b63a67c7311e9b635c2 363 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 203 353 1.7E-47 T 29-03-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 A616_RS31810 1f62c7b7ee821b63a67c7311e9b635c2 363 SUPERFAMILY SSF53697 59 346 2.62E-60 T 29-03-2018 A616_RS31810 1f62c7b7ee821b63a67c7311e9b635c2 363 Gene3D G3DSA:3.40.50.10490 11 181 2.0E-13 T 29-03-2018 A616_RS23505 511a2afd35c7bd503b18552f866f2537 270 SUPERFAMILY SSF53800 3 244 3.92E-25 T 29-03-2018 A616_RS23505 511a2afd35c7bd503b18552f866f2537 270 Gene3D G3DSA:3.40.50.1400 125 245 4.0E-14 T 29-03-2018 A616_RS23505 511a2afd35c7bd503b18552f866f2537 270 Pfam PF01903 CbiX 142 225 3.6E-5 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A616_RS23505 511a2afd35c7bd503b18552f866f2537 270 Pfam PF01903 CbiX 11 122 2.2E-12 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A616_RS23505 511a2afd35c7bd503b18552f866f2537 270 Gene3D G3DSA:3.40.50.1400 1 124 6.3E-19 T 29-03-2018 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 Pfam PF00376 MerR family regulatory protein 8 42 1.2E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 Gene3D G3DSA:1.10.10.10 99 131 0.077 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 SUPERFAMILY SSF46955 7 97 4.58E-12 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 Gene3D G3DSA:1.10.1660.10 1 98 1.1E-15 T 29-03-2018 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 SUPERFAMILY SSF46955 121 216 3.02E-20 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 Pfam PF13411 MerR HTH family regulatory protein 122 189 1.0E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 ProSitePatterns PS00552 MerR-type HTH domain signature. 125 147 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 SMART SM00422 122 194 3.5E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 SMART SM00422 4 72 5.8E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15145 5a1d3ae94553a5767c79a17558d4e4b0 234 Gene3D G3DSA:1.10.1660.10 132 231 9.3E-21 T 29-03-2018 A616_RS31330 f460d79705700bc76b4c084ce4b25c77 195 SUPERFAMILY SSF88659 104 175 5.98E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31330 f460d79705700bc76b4c084ce4b25c77 195 SUPERFAMILY SSF88946 4 104 8.04E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31330 f460d79705700bc76b4c084ce4b25c77 195 Gene3D G3DSA:1.10.1740.10 1 103 3.8E-24 T 29-03-2018 A616_RS31330 f460d79705700bc76b4c084ce4b25c77 195 Gene3D G3DSA:1.10.10.10 104 194 2.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31330 f460d79705700bc76b4c084ce4b25c77 195 Pfam PF04542 Sigma-70 region 2 26 92 6.4E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31330 f460d79705700bc76b4c084ce4b25c77 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 173 1.2E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22515 d005100757e9705a0c60cb39f7bdcbcd 115 Pfam PF04024 PspC domain 4 60 1.1E-16 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 SMART SM00849 12 196 5.0E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 Gene3D G3DSA:3.40.250.10 267 354 1.9E-8 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 Gene3D G3DSA:3.40.250.10 357 472 4.0E-25 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 SUPERFAMILY SSF52821 366 470 1.44E-30 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 SUPERFAMILY SSF56281 4 261 1.26E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 SMART SM00450 372 467 6.0E-20 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 SUPERFAMILY SSF52821 236 329 4.85E-12 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 Gene3D G3DSA:3.60.15.10 1 263 1.1E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 Pfam PF00581 Rhodanese-like domain 374 462 4.6E-13 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15840 32291bf57eae4d6e637c0afbd530629c 472 Pfam PF00753 Metallo-beta-lactamase superfamily 13 188 3.8E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12215 d22563835711f508ad850d15fba6a933 177 Gene3D G3DSA:2.160.10.10 2 174 1.7E-40 T 29-03-2018 A616_RS12215 d22563835711f508ad850d15fba6a933 177 SUPERFAMILY SSF51161 5 169 2.36E-47 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS12215 d22563835711f508ad850d15fba6a933 177 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 7.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS12215 d22563835711f508ad850d15fba6a933 177 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 1.6E-6 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 3 193 3.9E-109 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 92 103 - T 29-03-2018 IPR018215 ClpP, Ser active site A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 195 45.484 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 Pfam PF00574 Clp protease 15 194 2.4E-90 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 SUPERFAMILY SSF52096 12 196 7.46E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 PRINTS PR00127 Clp protease catalytic subunit P signature 170 189 2.0E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 2.0E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 2.0E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 2.0E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 2.0E-55 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 114 127 - T 29-03-2018 IPR033135 ClpP, histidine active site A616_RS29115 6b5b09a0b08b805241f3980e98643c33 200 Gene3D G3DSA:3.90.226.10 4 196 6.2E-49 T 29-03-2018 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 11 435 1.4E-134 T 29-03-2018 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 Gene3D G3DSA:3.40.462.10 188 404 5.8E-48 T 29-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain A616_RS30590 319bd1a45fe66a54cef546615308430d 438 PIRSF PIRSF000136 1 438 5.7E-141 T 29-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 22 55 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 Pfam PF04030 D-arabinono-1,4-lactone oxidase 181 433 8.1E-77 T 29-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 SUPERFAMILY SSF56176 7 187 3.13E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 Gene3D G3DSA:3.30.465.10 73 187 1.2E-28 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 Gene3D G3DSA:3.30.43.10 2 72 2.8E-16 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A616_RS30590 319bd1a45fe66a54cef546615308430d 438 Pfam PF01565 FAD binding domain 22 157 2.0E-27 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 Gene3D G3DSA:3.90.1150.10 8 89 2.1E-9 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 258 295 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 SUPERFAMILY SSF53383 21 452 5.59E-132 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 24 450 1.3E-171 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 PIRSF PIRSF000521 40 453 3.7E-29 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 Pfam PF00202 Aminotransferase class-III 38 448 1.2E-115 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 12 453 51.904 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 Gene3D G3DSA:3.90.1150.10 334 453 4.8E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29980 dc1005e39dd6484794c1345492cab0a0 460 Gene3D G3DSA:3.40.640.10 90 333 1.9E-68 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 8.6E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 Gene3D G3DSA:3.30.1340.10 1 82 4.3E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.3E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.3E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.3E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.7E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS29130 b4dd8c165d47c07eedbe17811bcb3b2f 85 SUPERFAMILY SSF55594 1 83 1.57E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 581 8.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 600 8.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 548 8.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 562 8.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SMART SM00304 205 257 3.1E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 Gene3D G3DSA:1.10.287.130 388 452 6.0E-16 T 29-03-2018 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 498 602 2.2E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 Gene3D G3DSA:3.30.565.10 456 606 1.1E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SUPERFAMILY SSF158472 207 255 2.62E-7 T 29-03-2018 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 391 452 2.3E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SUPERFAMILY SSF55874 447 603 1.83E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SMART SM00388 390 456 4.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SUPERFAMILY SSF55785 261 373 1.9E-5 T 29-03-2018 IPR000014 PAS domain A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SUPERFAMILY SSF47384 382 455 1.41E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 Gene3D G3DSA:3.30.450.20 238 387 1.2E-8 T 29-03-2018 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 Pfam PF00672 HAMP domain 207 252 3.3E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS27225 1a52bc27fc87c18f7f89673b81025600 606 SMART SM00387 497 603 1.4E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 Gene3D G3DSA:3.30.1490.20 98 163 1.7E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 295 2.5E-90 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 SUPERFAMILY SSF52440 1 95 1.25E-29 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 PIRSF PIRSF039102 1 52 1.1E-11 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 PIRSF PIRSF039102 41 304 4.4E-88 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 SUPERFAMILY SSF56059 96 303 3.86E-48 T 29-03-2018 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 63 74 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 240 267 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 Pfam PF07478 D-ala D-ala ligase C-terminus 124 293 4.6E-49 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 Gene3D G3DSA:3.30.470.20 164 305 1.8E-34 T 29-03-2018 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 Gene3D G3DSA:3.40.50.20 1 97 4.0E-37 T 29-03-2018 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 Pfam PF01820 D-ala D-ala ligase N-terminus 2 86 1.8E-22 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS15895 043139a04de24fbd2b5f127df9dfe21b 308 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 297 35.274 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS20255 9f51b87183d4e08bc19dce0e1b0042a9 112 Gene3D G3DSA:1.10.10.10 1 112 3.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20255 9f51b87183d4e08bc19dce0e1b0042a9 112 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 96 2.8E-32 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like A616_RS20255 9f51b87183d4e08bc19dce0e1b0042a9 112 SUPERFAMILY SSF88659 1 97 3.92E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS20255 9f51b87183d4e08bc19dce0e1b0042a9 112 Hamap MF_00245 UPF0122 protein . 2 105 20.092 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like A616_RS20895 a9a9878cfbdb356b6e4cda3faf9d95dc 399 SUPERFAMILY SSF103473 4 388 1.96E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS20895 a9a9878cfbdb356b6e4cda3faf9d95dc 399 Gene3D G3DSA:1.20.1250.20 198 389 1.6E-17 T 29-03-2018 A616_RS20895 a9a9878cfbdb356b6e4cda3faf9d95dc 399 Gene3D G3DSA:1.20.1250.20 1 197 2.8E-17 T 29-03-2018 A616_RS20895 a9a9878cfbdb356b6e4cda3faf9d95dc 399 Pfam PF05977 Transmembrane secretion effector 4 383 4.2E-15 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 144 294 2.0E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 SMART SM00478 145 310 7.0E-32 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 Gene3D G3DSA:1.10.1670.10 260 310 5.2E-13 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 Gene3D G3DSA:3.30.310.20 17 134 5.8E-18 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 SUPERFAMILY SSF48150 124 309 8.01E-46 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 Gene3D G3DSA:1.10.340.30 135 256 6.2E-26 T 29-03-2018 A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 241 265 - T 29-03-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 A616_RS01895 de575b0662a91eef1a1361a7b69b6cb2 310 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 71 140 8.5E-6 T 29-03-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 Pfam PF07676 WD40-like Beta Propeller Repeat 107 130 0.0076 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 SUPERFAMILY SSF53474 338 592 3.48E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 Gene3D G3DSA:3.40.50.1820 330 600 8.9E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 Pfam PF00326 Prolyl oligopeptidase family 387 593 4.6E-43 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 Gene3D G3DSA:2.130.10.120 12 160 2.4E-12 T 29-03-2018 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 Gene3D G3DSA:2.130.10.120 161 327 5.2E-25 T 29-03-2018 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 SUPERFAMILY SSF82171 18 327 1.02E-31 T 29-03-2018 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 453 473 8.6E-8 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 369 387 8.6E-8 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A616_RS14800 08716b4e5332188b4b03701d0f361ced 600 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 419 8.6E-8 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 SUPERFAMILY SSF52540 5 255 8.83E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 Pfam PF00005 ABC transporter 26 184 3.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 Gene3D G3DSA:3.40.50.300 2 335 1.7E-81 T 29-03-2018 A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 SMART SM00382 34 242 9.7E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 8.5E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14785 94fc183ba80b9a45b81f83d44b8986fc 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 1.5E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS05370 a0f1ac388e6ece14e4e723babf87aa76 164 Gene3D G3DSA:3.40.630.30 3 159 1.7E-13 T 29-03-2018 A616_RS05370 a0f1ac388e6ece14e4e723babf87aa76 164 Pfam PF00583 Acetyltransferase (GNAT) family 33 136 1.0E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS05370 a0f1ac388e6ece14e4e723babf87aa76 164 SUPERFAMILY SSF55729 18 136 1.08E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 133 7.2E-35 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 SUPERFAMILY SSF50129 1 172 3.2E-58 T 29-03-2018 IPR011032 GroES-like A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 SMART SM00829 8 334 1.3E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 Gene3D G3DSA:3.90.180.10 1 163 6.7E-63 T 29-03-2018 A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 Gene3D G3DSA:3.90.180.10 272 337 0.098 T 29-03-2018 A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 Pfam PF00107 Zinc-binding dehydrogenase 175 300 8.1E-34 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 SUPERFAMILY SSF51735 139 304 1.86E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS25745 74fbd1a368248c03aa64eef02715abca 337 Gene3D G3DSA:3.40.50.720 164 271 3.3E-30 T 29-03-2018 A616_RS08745 0cd4c1ce10276a981bcfef30aafb548e 403 Pfam PF02687 FtsX-like permease family 309 395 1.7E-15 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS08745 0cd4c1ce10276a981bcfef30aafb548e 403 Pfam PF12704 MacB-like periplasmic core domain 21 242 8.3E-43 T 29-03-2018 IPR025857 MacB-like periplasmic core domain A616_RS12780 0c70ae3566c70e3c29f87083c1295cee 325 SUPERFAMILY SSF161098 96 309 2.49E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12780 0c70ae3566c70e3c29f87083c1295cee 325 Gene3D G3DSA:1.10.3720.10 1 310 2.8E-36 T 29-03-2018 A616_RS12780 0c70ae3566c70e3c29f87083c1295cee 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 320 1.1E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS01140 7212151bf3ca0d9197146caf85005b8c 281 Pfam PF01063 Amino-transferase class IV 29 253 7.4E-53 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS01140 7212151bf3ca0d9197146caf85005b8c 281 Gene3D G3DSA:3.30.470.10 1 117 6.0E-32 T 29-03-2018 A616_RS01140 7212151bf3ca0d9197146caf85005b8c 281 ProSitePatterns PS00770 Aminotransferases class-IV signature. 179 208 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS01140 7212151bf3ca0d9197146caf85005b8c 281 SUPERFAMILY SSF56752 2 275 8.63E-78 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS01140 7212151bf3ca0d9197146caf85005b8c 281 Gene3D G3DSA:3.20.10.10 122 278 3.6E-43 T 29-03-2018 A616_RS22385 dc78db50f19481af8020e9fd626c2035 319 Pfam PF00005 ABC transporter 22 162 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS22385 dc78db50f19481af8020e9fd626c2035 319 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS22385 dc78db50f19481af8020e9fd626c2035 319 SMART SM00382 30 211 2.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS22385 dc78db50f19481af8020e9fd626c2035 319 SUPERFAMILY SSF52540 3 227 4.52E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22385 dc78db50f19481af8020e9fd626c2035 319 Gene3D G3DSA:3.40.50.300 2 279 2.4E-61 T 29-03-2018 A616_RS07320 933676e766403153b96f7d54df373a75 586 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 248 1.4E-98 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 A616_RS07320 933676e766403153b96f7d54df373a75 586 Gene3D G3DSA:3.30.413.10 381 573 1.5E-19 T 29-03-2018 A616_RS07320 933676e766403153b96f7d54df373a75 586 Gene3D G3DSA:3.40.1010.10 2 128 4.0E-32 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07320 933676e766403153b96f7d54df373a75 586 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 215 3.8E-37 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07320 933676e766403153b96f7d54df373a75 586 SUPERFAMILY SSF56014 449 565 2.88E-21 T 29-03-2018 A616_RS07320 933676e766403153b96f7d54df373a75 586 Gene3D G3DSA:3.30.950.10 129 246 4.8E-52 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07320 933676e766403153b96f7d54df373a75 586 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 484 500 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS07320 933676e766403153b96f7d54df373a75 586 SUPERFAMILY SSF53790 1 256 1.11E-57 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07320 933676e766403153b96f7d54df373a75 586 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 463 565 4.1E-9 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS10795 642b7440769e167777de32b61a847530 381 Gene3D G3DSA:3.40.640.10 13 257 5.1E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS10795 642b7440769e167777de32b61a847530 381 Gene3D G3DSA:3.90.1150.10 264 381 1.2E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS10795 642b7440769e167777de32b61a847530 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A616_RS10795 642b7440769e167777de32b61a847530 381 Pfam PF00266 Aminotransferase class-V 5 364 5.2E-84 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS10795 642b7440769e167777de32b61a847530 381 PIRSF PIRSF005572 2 381 5.4E-129 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A616_RS10795 642b7440769e167777de32b61a847530 381 SUPERFAMILY SSF53383 4 377 2.99E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Pfam PF12002 MgsA AAA+ ATPase C terminal 273 435 5.9E-72 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Gene3D G3DSA:1.20.272.10 257 351 1.0E-41 T 29-03-2018 A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Gene3D G3DSA:1.10.8.60 159 247 6.3E-22 T 29-03-2018 A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Gene3D G3DSA:3.40.50.300 7 158 5.4E-32 T 29-03-2018 A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Gene3D G3DSA:1.10.3710.10 354 447 5.9E-26 T 29-03-2018 A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 SUPERFAMILY SSF52540 15 234 6.69E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 57 164 1.4E-16 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 SUPERFAMILY SSF48019 258 440 1.02E-75 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 SMART SM00382 53 170 4.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10785 26793d57c4684556af0defc3ddd8c79f 452 Pfam PF16193 AAA C-terminal domain 195 272 8.4E-29 T 29-03-2018 IPR032423 AAA C-terminal domain A616_RS08290 e17f1d4a0bdc87663d98970bf725d01e 326 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 15 143 3.6E-45 T 29-03-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 A616_RS08290 e17f1d4a0bdc87663d98970bf725d01e 326 Gene3D G3DSA:3.90.70.10 12 182 3.0E-12 T 29-03-2018 A616_RS08290 e17f1d4a0bdc87663d98970bf725d01e 326 Pfam PF16169 Domain of unknown function (DUF4872) 156 325 5.5E-44 T 29-03-2018 IPR032369 Domain of unknown function DUF4872 A616_RS08715 76d52bc867127053fd65412103bc2f9a 217 Gene3D G3DSA:3.40.109.10 1 217 1.7E-45 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS08715 76d52bc867127053fd65412103bc2f9a 217 Pfam PF00881 Nitroreductase family 16 183 3.8E-32 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS08715 76d52bc867127053fd65412103bc2f9a 217 SUPERFAMILY SSF55469 10 214 1.02E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS08715 76d52bc867127053fd65412103bc2f9a 217 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 7 207 3.1E-72 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 A616_RS23100 f04851063680074945c55abf3f3f45e6 179 SUPERFAMILY SSF46767 89 170 2.09E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS23100 f04851063680074945c55abf3f3f45e6 179 SUPERFAMILY SSF53155 8 86 9.81E-10 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS23100 f04851063680074945c55abf3f3f45e6 179 Gene3D G3DSA:1.10.10.10 86 172 5.4E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23100 f04851063680074945c55abf3f3f45e6 179 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 170 1.8E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS23100 f04851063680074945c55abf3f3f45e6 179 Gene3D G3DSA:3.30.160.70 1 85 1.9E-11 T 29-03-2018 A616_RS23100 f04851063680074945c55abf3f3f45e6 179 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS23100 f04851063680074945c55abf3f3f45e6 179 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 169 9.8E-35 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS25575 11a00b48f51dca9e58a02c82047751ed 287 SUPERFAMILY SSF55729 2 122 1.69E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25575 11a00b48f51dca9e58a02c82047751ed 287 Pfam PF00583 Acetyltransferase (GNAT) family 192 273 3.3E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25575 11a00b48f51dca9e58a02c82047751ed 287 Pfam PF13508 Acetyltransferase (GNAT) domain 34 120 1.4E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25575 11a00b48f51dca9e58a02c82047751ed 287 SUPERFAMILY SSF55729 109 277 7.32E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25575 11a00b48f51dca9e58a02c82047751ed 287 Gene3D G3DSA:3.40.630.30 148 285 7.2E-20 T 29-03-2018 A616_RS25575 11a00b48f51dca9e58a02c82047751ed 287 Gene3D G3DSA:3.40.630.30 1 147 9.7E-14 T 29-03-2018 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 SUPERFAMILY SSF158472 168 218 2.35E-9 T 29-03-2018 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 223 278 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 SUPERFAMILY SSF47384 205 287 3.92E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 Gene3D G3DSA:3.30.565.10 280 443 1.7E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 SMART SM00387 331 443 4.5E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 SMART SM00304 168 221 6.3E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 331 441 2.0E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 440 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 396 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 8.1E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 SUPERFAMILY SSF55874 276 441 2.49E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 Pfam PF00672 HAMP domain 168 218 2.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 Gene3D G3DSA:1.10.287.130 212 279 4.1E-12 T 29-03-2018 A616_RS14560 6c39f2dcea978a418c64d9a0f07c4792 448 SMART SM00388 222 286 1.7E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 3.7E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 Pfam PF00155 Aminotransferase class I and II 114 446 1.7E-23 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 Gene3D G3DSA:3.40.640.10 119 361 1.6E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 SMART SM00345 18 77 1.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09270 afdd09686e9057a465702de74d6c3867 459 SUPERFAMILY SSF46785 7 86 1.58E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09270 afdd09686e9057a465702de74d6c3867 459 SUPERFAMILY SSF53383 104 458 1.38E-74 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS09270 afdd09686e9057a465702de74d6c3867 459 Gene3D G3DSA:1.10.10.10 6 79 9.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09270 afdd09686e9057a465702de74d6c3867 459 Gene3D G3DSA:3.90.1150.10 362 459 1.6E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 Pfam PF00005 ABC transporter 25 181 9.8E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 3.7E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 Gene3D G3DSA:3.40.50.300 1 324 1.3E-80 T 29-03-2018 A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 SMART SM00382 33 231 3.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 7.3E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS08820 749dc2e8245dfc77c2abac52a54311c5 324 SUPERFAMILY SSF52540 4 252 1.15E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 Gene3D G3DSA:3.40.50.300 1 206 6.9E-39 T 29-03-2018 A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 SMART SM00833 251 337 1.2E-10 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 SUPERFAMILY SSF90002 251 337 1.44E-13 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 251 336 1.1E-14 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 SUPERFAMILY SSF52540 4 184 1.31E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 Gene3D G3DSA:3.30.1220.10 225 338 6.7E-14 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS00675 7a732186994a7ef4b077a44ebfd76def 338 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 187 8.0E-43 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A616_RS17510 a30f294dc7c400715c96387b05b19f6f 734 SUPERFAMILY SSF49785 296 410 1.82E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS17510 a30f294dc7c400715c96387b05b19f6f 734 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 12 154 3.5E-21 T 29-03-2018 A616_RS17510 a30f294dc7c400715c96387b05b19f6f 734 Gene3D G3DSA:2.60.120.200 4 202 1.3E-30 T 29-03-2018 A616_RS17510 a30f294dc7c400715c96387b05b19f6f 734 SUPERFAMILY SSF49899 2 178 7.74E-26 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A616_RS17510 a30f294dc7c400715c96387b05b19f6f 734 Gene3D G3DSA:2.60.120.260 276 437 1.4E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 336 360 1.9E-5 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 93 113 1.9E-5 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 Gene3D G3DSA:2.40.50.100 66 144 3.0E-10 T 29-03-2018 A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 397 2.8E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 Gene3D G3DSA:1.20.1600.10 263 455 1.4E-15 T 29-03-2018 A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 Gene3D G3DSA:1.10.287.470 172 228 2.1E-10 T 29-03-2018 A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 SUPERFAMILY SSF111369 99 170 2.75E-5 T 29-03-2018 A616_RS08735 370e6c51ffadaabf5db513bcaad6fcc8 531 SUPERFAMILY SSF111369 240 405 4.58E-7 T 29-03-2018 A616_RS20410 88fbb917cf8377a5f5f001d7e0be9d54 534 PIRSF PIRSF005690 26 509 1.3E-179 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS20410 88fbb917cf8377a5f5f001d7e0be9d54 534 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 40 495 2.1E-190 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS24220 01ed77918d1e07a2b383acf3007b84be 411 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 233 400 1.3E-31 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS24220 01ed77918d1e07a2b383acf3007b84be 411 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 402 3.5E-87 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS07340 623cbf5593a4ff72f6cbbeb285a957cd 378 SUPERFAMILY SSF111342 10 293 4.45E-81 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A616_RS07340 623cbf5593a4ff72f6cbbeb285a957cd 378 Gene3D G3DSA:3.30.2110.10 17 189 4.1E-62 T 29-03-2018 A616_RS07340 623cbf5593a4ff72f6cbbeb285a957cd 378 PIRSF PIRSF026782 11 369 2.6E-119 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A616_RS07340 623cbf5593a4ff72f6cbbeb285a957cd 378 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 22 363 5.8E-64 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A616_RS07340 623cbf5593a4ff72f6cbbeb285a957cd 378 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 15 364 28.723 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A616_RS07340 623cbf5593a4ff72f6cbbeb285a957cd 378 Pfam PF01888 CbiD 15 275 2.1E-93 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A616_RS25785 433b4e29da8b0c43d453f1dbbcc58fe2 259 Gene3D G3DSA:1.10.10.60 59 122 1.5E-12 T 29-03-2018 A616_RS25785 433b4e29da8b0c43d453f1dbbcc58fe2 259 SMART SM00342 21 104 5.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS25785 433b4e29da8b0c43d453f1dbbcc58fe2 259 Pfam PF12833 Helix-turn-helix domain 27 105 7.1E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS25785 433b4e29da8b0c43d453f1dbbcc58fe2 259 SUPERFAMILY SSF46689 7 54 2.64E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25785 433b4e29da8b0c43d453f1dbbcc58fe2 259 SUPERFAMILY SSF46689 57 107 4.93E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25785 433b4e29da8b0c43d453f1dbbcc58fe2 259 Gene3D G3DSA:1.10.10.60 3 58 2.6E-14 T 29-03-2018 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 SMART SM01294 688 752 8.2E-4 T 29-03-2018 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 SMART SM00825 Beta-ketoacyl synthase 31 458 5.1E-168 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Gene3D G3DSA:3.40.47.10 296 459 2.2E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 SMART SM00823 Phosphopantetheine attachment site 687 756 0.0074 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 805 935 2.9E-19 T 29-03-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Gene3D G3DSA:1.10.1200.10 680 777 1.2E-20 T 29-03-2018 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Pfam PF00550 Phosphopantetheine attachment site 689 752 2.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 30 280 1.1E-73 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Gene3D G3DSA:3.90.70.10 778 965 1.2E-7 T 29-03-2018 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 SUPERFAMILY SSF47336 683 752 4.71E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 519 2.2E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Gene3D G3DSA:3.40.47.10 21 292 4.8E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 288 405 5.2E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 SUPERFAMILY SSF53901 27 149 1.27E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 SUPERFAMILY SSF53901 177 402 1.27E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18500 b5a17be2a1a800781db9974f68724117 1121 ProSitePatterns PS00012 Phosphopantetheine attachment site. 711 726 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS17580 4fbf68bc588470b8fe55507cf630371d 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS17580 4fbf68bc588470b8fe55507cf630371d 59 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS17580 4fbf68bc588470b8fe55507cf630371d 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 14 57 5.8E-19 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 SUPERFAMILY SSF51430 7 275 1.44E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 Pfam PF00248 Aldo/keto reductase family 31 266 2.8E-50 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 Gene3D G3DSA:3.20.20.100 2 279 2.1E-101 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PRINTS PR00069 Aldo-keto reductase signature 201 225 6.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PRINTS PR00069 Aldo-keto reductase signature 40 64 6.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PRINTS PR00069 Aldo-keto reductase signature 130 147 6.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PRINTS PR00069 Aldo-keto reductase signature 100 118 6.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PRINTS PR00069 Aldo-keto reductase signature 164 193 6.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PIRSF PIRSF000097 120 275 9.1E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25290 8d370de68292e693f1a5f99da4b609a0 280 PIRSF PIRSF000097 3 125 4.6E-42 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS19635 7a70d58917fa5bc7c251936563c80f70 191 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 189 2.8E-53 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A616_RS19635 7a70d58917fa5bc7c251936563c80f70 191 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 3.4E-16 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS19635 7a70d58917fa5bc7c251936563c80f70 191 PIRSF PIRSF000847 1 191 3.8E-49 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A616_RS19635 7a70d58917fa5bc7c251936563c80f70 191 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 Gene3D G3DSA:3.40.1770.10 195 554 4.0E-163 T 29-03-2018 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 Gene3D G3DSA:3.40.1770.10 10 152 2.3E-28 T 29-03-2018 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 Pfam PF17391 Urocanase N-terminal domain 11 137 7.9E-60 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 TIGRFAM TIGR01228 hutU: urocanate hydratase 11 553 2.1E-292 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 Pfam PF01175 Urocanase Rossmann-like domain 140 348 4.1E-88 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 Pfam PF17392 Urocanase C-terminal domain 351 545 3.2E-94 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 ProSitePatterns PS01233 Urocanase signature. 441 456 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 Hamap MF_00577 Urocanate hydratase [hutU]. 4 555 49.786 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 PIRSF PIRSF001423 1 556 8.5E-291 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23310 5e960b18a36f00b3408811c88c0648cd 556 SUPERFAMILY SSF111326 8 555 4.19E-255 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS04295 6b8c3c6867756752a839fbd0138c4cde 360 SUPERFAMILY SSF53756 90 329 2.26E-10 T 29-03-2018 A616_RS04295 6b8c3c6867756752a839fbd0138c4cde 360 Gene3D G3DSA:3.40.50.2000 157 317 2.5E-9 T 29-03-2018 A616_RS02235 6881e41dcaa2d7edf581e0a82883a36a 279 Gene3D G3DSA:1.10.3720.10 19 277 3.8E-36 T 29-03-2018 A616_RS02235 6881e41dcaa2d7edf581e0a82883a36a 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 265 2.6E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS02235 6881e41dcaa2d7edf581e0a82883a36a 279 SUPERFAMILY SSF161098 85 270 5.89E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 SMART SM00387 253 364 9.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 Gene3D G3DSA:3.30.565.10 212 366 5.1E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 SMART SM00388 141 208 4.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 PRINTS PR01780 Lantibiotic regulatory protein signature 313 328 2.4E-8 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 PRINTS PR01780 Lantibiotic regulatory protein signature 150 166 2.4E-8 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 PRINTS PR01780 Lantibiotic regulatory protein signature 113 127 2.4E-8 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 PRINTS PR01780 Lantibiotic regulatory protein signature 249 264 2.4E-8 T 29-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 Gene3D G3DSA:1.10.287.130 116 204 6.6E-13 T 29-03-2018 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 206 2.5E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 SUPERFAMILY SSF47384 128 208 2.75E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 363 1.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 SMART SM00304 81 133 0.0024 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS31710 e34acf81c894128fb6d13fee73a02fc8 368 SUPERFAMILY SSF55874 197 362 4.45E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 Gene3D G3DSA:2.40.50.100 5 170 2.0E-14 T 29-03-2018 A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 169 9.2E-44 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 Pfam PF00364 Biotin-requiring enzyme 95 166 2.9E-18 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 98 111 3.9E-13 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 130 143 3.9E-13 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 115 129 3.9E-13 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS14835 c1672811a3d1e3002987f33bf638888b 171 SUPERFAMILY SSF51230 92 168 6.41E-20 T 29-03-2018 IPR011053 Single hybrid motif A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 2.9E-17 T 29-03-2018 A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 SUPERFAMILY SSF46785 1 82 4.85E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 1.5E-19 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 Gene3D G3DSA:3.30.70.920 54 144 1.2E-26 T 29-03-2018 A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 SUPERFAMILY SSF54909 63 143 4.42E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 SMART SM00344 1 108 1.1E-39 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS24015 daf4534aa4015ea4a89b8be78a48592b 144 Gene3D G3DSA:1.10.10.10 1 52 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14295 0dcb1ee9d7c3a334c32d0236df65df79 286 SMART SM00382 35 225 5.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14295 0dcb1ee9d7c3a334c32d0236df65df79 286 SUPERFAMILY SSF52540 4 242 1.11E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14295 0dcb1ee9d7c3a334c32d0236df65df79 286 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 6 281 2.4E-108 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 A616_RS14295 0dcb1ee9d7c3a334c32d0236df65df79 286 Pfam PF00005 ABC transporter 26 176 4.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14295 0dcb1ee9d7c3a334c32d0236df65df79 286 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14295 0dcb1ee9d7c3a334c32d0236df65df79 286 Gene3D G3DSA:3.40.50.300 1 251 2.7E-68 T 29-03-2018 A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 Gene3D G3DSA:3.40.50.720 1 143 7.3E-15 T 29-03-2018 A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 Gene3D G3DSA:3.30.360.10 144 282 8.2E-56 T 29-03-2018 A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 Gene3D G3DSA:3.40.50.150 480 772 1.1E-21 T 29-03-2018 A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 Pfam PF08242 Methyltransferase domain 575 679 3.7E-14 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 SUPERFAMILY SSF53335 550 734 1.42E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 TIGRFAM TIGR01761 thiaz-red: thiazolinyl imide reductase 7 342 5.3E-90 T 29-03-2018 IPR010091 Thiazolinyl imide reductase A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 SUPERFAMILY SSF51735 13 138 1.39E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS24425 01e80e81b36674d7326dce9cda94b9f1 775 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 123 4.0E-17 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Pfam PF03979 Sigma-70 factor, region 1.1 15 88 6.9E-15 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 139 364 2.5E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 SUPERFAMILY SSF88659 216 289 3.92E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Pfam PF00140 Sigma-70 factor, region 1.2 105 138 2.8E-19 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Gene3D G3DSA:1.10.601.10 2 212 2.0E-78 T 29-03-2018 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 SUPERFAMILY SSF88946 104 213 7.85E-55 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Gene3D G3DSA:1.10.10.10 305 376 6.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Pfam PF04539 Sigma-70 region 3 222 298 2.2E-31 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Pfam PF04542 Sigma-70 region 2 143 212 4.0E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Pfam PF04545 Sigma-70, region 4 311 364 5.2E-20 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 8 376 34.287 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 SUPERFAMILY SSF88659 273 374 6.73E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 Gene3D G3DSA:1.10.10.10 213 263 1.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 PRINTS PR00046 Major sigma-70 factor signature 167 180 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 PRINTS PR00046 Major sigma-70 factor signature 191 199 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 PRINTS PR00046 Major sigma-70 factor signature 336 351 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 PRINTS PR00046 Major sigma-70 factor signature 315 327 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 PRINTS PR00046 Major sigma-70 factor signature 351 362 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 139 375 3.8E-125 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 167 180 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11690 08be4a49315c268a6ae92048388eae4d 376 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 336 362 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 Gene3D G3DSA:3.40.50.620 4 158 1.2E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS29325 490d394b9e575f2933817d36a087b85c 419 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 Gene3D G3DSA:1.20.5.470 363 396 1.5E-12 T 29-03-2018 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 395 1.1E-165 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 SUPERFAMILY SSF52402 3 203 8.16E-48 T 29-03-2018 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 SUPERFAMILY SSF69864 171 398 1.57E-94 T 29-03-2018 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 397 54.888 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 Pfam PF00764 Arginosuccinate synthase 7 392 4.2E-177 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29325 490d394b9e575f2933817d36a087b85c 419 Gene3D G3DSA:3.90.1260.10 159 353 1.9E-86 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS15340 4a42b85a91ba05e871923ca49274a2fe 255 PIRSF PIRSF000090 1 255 3.3E-73 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A616_RS15340 4a42b85a91ba05e871923ca49274a2fe 255 Pfam PF01012 Electron transfer flavoprotein domain 23 204 1.6E-49 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS15340 4a42b85a91ba05e871923ca49274a2fe 255 Gene3D G3DSA:3.40.50.620 1 255 1.7E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS15340 4a42b85a91ba05e871923ca49274a2fe 255 SUPERFAMILY SSF52402 1 239 7.67E-74 T 29-03-2018 A616_RS15340 4a42b85a91ba05e871923ca49274a2fe 255 SMART SM00893 21 209 2.4E-59 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS10305 9514b7acb27af92e966731e205979517 565 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 495 513 1.8E-31 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 98 117 1.8E-31 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 472 491 1.8E-31 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 353 369 1.8E-31 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 442 461 1.8E-31 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 94 267 1.7E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS10305 9514b7acb27af92e966731e205979517 565 Gene3D G3DSA:3.40.50.300 49 256 9.5E-30 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 SUPERFAMILY SSF54211 353 535 6.45E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS10305 9514b7acb27af92e966731e205979517 565 Gene3D G3DSA:1.10.8.60 257 329 5.6E-10 T 29-03-2018 A616_RS10305 9514b7acb27af92e966731e205979517 565 Gene3D G3DSA:3.30.230.10 330 553 9.0E-51 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS10305 9514b7acb27af92e966731e205979517 565 SMART SM00382 90 268 1.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10305 9514b7acb27af92e966731e205979517 565 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 445 453 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A616_RS10305 9514b7acb27af92e966731e205979517 565 SUPERFAMILY SSF52540 236 329 1.14E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10305 9514b7acb27af92e966731e205979517 565 SUPERFAMILY SSF52540 57 205 1.14E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10305 9514b7acb27af92e966731e205979517 565 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 7 535 2.6E-265 T 29-03-2018 IPR014251 Sporulation protease LonB A616_RS10305 9514b7acb27af92e966731e205979517 565 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 174 189 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS10305 9514b7acb27af92e966731e205979517 565 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 345 536 1.8E-31 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 SUPERFAMILY SSF56300 203 432 2.17E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 SUPERFAMILY SSF56091 694 766 5.76E-7 T 29-03-2018 A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 SUPERFAMILY SSF56091 518 592 5.76E-7 T 29-03-2018 A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 Gene3D G3DSA:3.40.50.300 7 170 2.3E-12 T 29-03-2018 A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 Gene3D G3DSA:3.60.21.10 199 454 4.5E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 Gene3D G3DSA:3.30.470.30 521 715 1.2E-8 T 29-03-2018 A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 Pfam PF00149 Calcineurin-like phosphoesterase 212 332 4.2E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 SUPERFAMILY SSF52540 10 131 1.31E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15155 f8b9deb0d774dd7bb89a4963a35b73b5 861 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 481 793 4.5E-26 T 29-03-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 SMART SM00448 2 112 6.7E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 Gene3D G3DSA:3.40.50.2300 1 114 6.8E-32 T 29-03-2018 A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 224 2.1E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 Gene3D G3DSA:1.10.10.10 115 231 1.9E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 Pfam PF00072 Response regulator receiver domain 4 112 4.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 SMART SM00862 150 224 5.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 SUPERFAMILY SSF52172 2 125 1.57E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03235 3d90ce564cc3770d1ff18bc3b34d7407 232 SUPERFAMILY SSF46894 129 225 4.82E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS07225 5bfc1c764b0815e582c4d9bb110f6090 193 Pfam PF05573 NosL 20 149 2.8E-16 T 29-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL A616_RS07225 5bfc1c764b0815e582c4d9bb110f6090 193 SUPERFAMILY SSF160387 55 157 7.06E-20 T 29-03-2018 A616_RS16750 2b71cccbf8d7b1ec05557290ac2d09b4 372 Gene3D G3DSA:3.40.50.300 3 348 4.8E-6 T 29-03-2018 A616_RS16750 2b71cccbf8d7b1ec05557290ac2d09b4 372 Pfam PF13479 AAA domain 17 251 9.3E-30 T 29-03-2018 A616_RS16750 2b71cccbf8d7b1ec05557290ac2d09b4 372 SUPERFAMILY SSF52540 15 104 1.5E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16750 2b71cccbf8d7b1ec05557290ac2d09b4 372 SUPERFAMILY SSF52540 137 167 1.5E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28510 e85c80b8a959207fde70be785cae56ba 190 Pfam PF02630 SCO1/SenC 28 171 1.1E-38 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28510 e85c80b8a959207fde70be785cae56ba 190 Gene3D G3DSA:3.40.30.10 23 190 7.3E-36 T 29-03-2018 A616_RS28510 e85c80b8a959207fde70be785cae56ba 190 SUPERFAMILY SSF52833 27 188 1.6E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS32275 cc338e5063240732834d571a059b246a 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 217 2.0E-53 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A616_RS32275 cc338e5063240732834d571a059b246a 238 Gene3D G3DSA:3.40.50.150 1 238 3.4E-40 T 29-03-2018 A616_RS32275 cc338e5063240732834d571a059b246a 238 PIRSF PIRSF003078 1 220 6.4E-58 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A616_RS32275 cc338e5063240732834d571a059b246a 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.615 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A616_RS32275 cc338e5063240732834d571a059b246a 238 Pfam PF02527 rRNA small subunit methyltransferase G 21 202 1.7E-55 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A616_RS32275 cc338e5063240732834d571a059b246a 238 SUPERFAMILY SSF53335 1 237 1.89E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 Pfam PF02803 Thiolase, C-terminal domain 269 385 3.3E-10 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 Gene3D G3DSA:3.40.47.10 252 380 1.8E-17 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 Pfam PF00108 Thiolase, N-terminal domain 6 190 7.5E-16 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 PIRSF PIRSF000429 2 391 1.6E-62 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 Gene3D G3DSA:3.40.47.10 2 242 9.5E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 ProSitePatterns PS00737 Thiolases signature 2. 331 347 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 SUPERFAMILY SSF53901 186 391 1.18E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 SUPERFAMILY SSF53901 14 117 1.18E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15530 405167cf375d9d1150aec51ac1a66483 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 78 96 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS13815 fbf8ff9d5477823c802ff657633e713e 266 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 69 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A616_RS13815 fbf8ff9d5477823c802ff657633e713e 266 SUPERFAMILY SSF51366 9 258 7.3E-82 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS13815 fbf8ff9d5477823c802ff657633e713e 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 2 254 4.5E-90 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A616_RS13815 fbf8ff9d5477823c802ff657633e713e 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 258 32.917 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A616_RS13815 fbf8ff9d5477823c802ff657633e713e 266 Gene3D G3DSA:3.20.20.70 3 261 5.2E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 662 1.9E-263 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SMART SM00292 593 670 5.1E-16 T 29-03-2018 IPR001357 BRCT domain A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SUPERFAMILY SSF47781 401 583 1.22E-64 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:3.40.50.10190 570 671 6.3E-26 T 29-03-2018 IPR001357 BRCT domain A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 319 395 4.9E-32 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:3.30.1490.70 239 318 1.1E-28 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:1.10.150.20 504 569 6.1E-28 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:1.10.287.610 2 69 1.4E-25 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SMART SM00532 5 444 1.2E-273 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 594 666 3.6E-14 T 29-03-2018 IPR001357 BRCT domain A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Pfam PF12826 Helix-hairpin-helix motif 508 571 4.0E-24 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 116 145 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 6 315 3.1E-128 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Pfam PF14520 Helix-hairpin-helix domain 442 497 5.2E-4 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:1.10.150.20 428 503 1.9E-25 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SUPERFAMILY SSF56091 4 313 6.84E-121 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SUPERFAMILY SSF52113 594 669 5.09E-20 T 29-03-2018 IPR001357 BRCT domain A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:3.30.470.30 120 238 8.1E-51 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Hamap MF_01588 DNA ligase [ligA]. 4 667 54.629 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SMART SM00278 542 561 0.6 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SMART SM00278 478 497 28.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SMART SM00278 442 461 150.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 SUPERFAMILY SSF50249 314 398 6.68E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 404 430 1.1E-11 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 PIRSF PIRSF001604 1 671 8.5E-257 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 Gene3D G3DSA:2.40.50.140 319 387 8.5E-31 T 29-03-2018 A616_RS03975 e2d8c2aaff57f537d0e72a10f1f4bea1 671 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 328 343 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 3.8E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 476 3.8E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 3.8E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 3.8E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Pfam PF00989 PAS fold 218 287 5.7E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Gene3D G3DSA:1.10.287.130 318 377 5.0E-16 T 29-03-2018 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Gene3D G3DSA:3.30.565.10 378 532 6.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 SMART SM00387 421 532 3.1E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 SUPERFAMILY SSF55874 386 528 1.13E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 SUPERFAMILY SSF55785 219 313 3.32E-12 T 29-03-2018 IPR000014 PAS domain A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 SMART SM00091 216 282 3.7E-7 T 29-03-2018 IPR000014 PAS domain A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 SUPERFAMILY SSF103190 40 170 3.1E-38 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Gene3D G3DSA:3.30.450.20 219 317 3.3E-11 T 29-03-2018 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 529 1.7E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 SUPERFAMILY SSF55890 326 393 8.24E-10 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Pfam PF17203 Single cache domain 3 40 170 1.8E-27 T 29-03-2018 IPR033463 Single cache domain 3 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Gene3D G3DSA:3.30.450.20 32 167 7.9E-24 T 29-03-2018 A616_RS18695 32ec77d27e858893aa0b2e9e675c36f4 536 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 323 367 1.8E-8 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Pfam PF12833 Helix-turn-helix domain 201 279 6.9E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 232 274 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 SMART SM00342 195 278 1.9E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Pfam PF02311 AraC-like ligand binding domain 34 100 6.2E-6 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 SUPERFAMILY SSF51215 24 99 8.5E-8 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 SUPERFAMILY SSF46689 181 228 3.31E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Gene3D G3DSA:2.60.120.280 7 173 1.8E-8 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Gene3D G3DSA:1.10.10.60 232 282 2.1E-14 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Gene3D G3DSA:3.40.50.1980 386 548 2.4E-26 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 262 5.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 278 5.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 SUPERFAMILY SSF53807 275 531 5.89E-39 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Pfam PF01497 Periplasmic binding protein 285 516 1.3E-21 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Gene3D G3DSA:3.40.50.1980 283 385 1.9E-10 T 29-03-2018 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 SUPERFAMILY SSF46689 231 281 2.15E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02030 0a82dc57168ca2ae1497f33fc3b5fa4c 549 Gene3D G3DSA:1.10.10.60 174 231 2.5E-13 T 29-03-2018 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 Gene3D G3DSA:1.10.10.10 137 217 8.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 59 90 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 SUPERFAMILY SSF88946 14 102 3.92E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 Pfam PF04542 Sigma-70 region 2 37 101 1.1E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 SUPERFAMILY SSF88659 142 214 4.49E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 213 1.6E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 Pfam PF08281 Sigma-70, region 4 160 211 3.8E-6 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04040 e4d7022edc92570a4bfd8d29ed9fc858 586 Gene3D G3DSA:1.10.1740.10 13 116 1.4E-23 T 29-03-2018 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 SUPERFAMILY SSF64158 79 312 7.59E-93 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 84 301 1.1E-87 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 Gene3D G3DSA:3.40.1450.10 79 304 1.3E-101 T 29-03-2018 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 SUPERFAMILY SSF53649 313 511 9.16E-75 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 SUPERFAMILY SSF53649 5 79 9.16E-75 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 Pfam PF01676 Metalloenzyme superfamily 6 500 2.0E-76 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 Gene3D G3DSA:3.40.720.10 305 513 3.8E-34 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 511 8.5E-215 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 PIRSF PIRSF001492 1 513 4.4E-205 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29030 7b6e4d9f39172beb4b0b82d591b92f95 513 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 512 49.972 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 SMART SM00421 795 852 3.2E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 SUPERFAMILY SSF52540 18 269 2.72E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 SUPERFAMILY SSF46894 791 858 4.42E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 812 828 2.0E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 798 812 2.0E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 828 840 2.0E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 Gene3D G3DSA:3.40.50.300 4 170 1.1E-6 T 29-03-2018 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 Gene3D G3DSA:1.10.10.10 787 858 2.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 SUPERFAMILY SSF48452 567 755 2.45E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 Pfam PF00196 Bacterial regulatory proteins, luxR family 797 850 1.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25670 344e9971baa45975169b5ba1c48b3efe 864 Gene3D G3DSA:1.25.40.10 330 786 9.1E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12515 abc2958fd9aa1962dce070d4639c8dde 333 Pfam PF01497 Periplasmic binding protein 86 305 2.5E-21 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS12515 abc2958fd9aa1962dce070d4639c8dde 333 SUPERFAMILY SSF53807 60 326 5.49E-49 T 29-03-2018 A616_RS12515 abc2958fd9aa1962dce070d4639c8dde 333 Gene3D G3DSA:3.40.50.1980 51 175 2.6E-19 T 29-03-2018 A616_RS12515 abc2958fd9aa1962dce070d4639c8dde 333 Gene3D G3DSA:3.40.50.1980 176 333 2.1E-27 T 29-03-2018 A616_RS13770 19178d2f002a85b177535768ad6edf77 287 SUPERFAMILY SSF53850 5 266 7.11E-74 T 29-03-2018 A616_RS13770 19178d2f002a85b177535768ad6edf77 287 Gene3D G3DSA:3.40.190.10 1 132 5.4E-18 T 29-03-2018 A616_RS13770 19178d2f002a85b177535768ad6edf77 287 Gene3D G3DSA:3.40.190.10 133 261 3.2E-24 T 29-03-2018 A616_RS13770 19178d2f002a85b177535768ad6edf77 287 Pfam PF02621 Menaquinone biosynthesis 5 261 2.9E-65 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme A616_RS13770 19178d2f002a85b177535768ad6edf77 287 Hamap MF_00995 Chorismate dehydratase [mqnA]. 6 265 28.148 T 29-03-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 Pfam PF00664 ABC transporter transmembrane region 20 292 6.3E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 SUPERFAMILY SSF90123 9 321 6.15E-68 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 Gene3D G3DSA:1.20.1560.10 3 324 2.6E-54 T 29-03-2018 A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 SMART SM00382 363 564 2.9E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 SUPERFAMILY SSF52540 326 573 6.49E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 Pfam PF00005 ABC transporter 354 502 1.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS04840 cc735ea0b59636202ad6c5ed0f04538b 583 Gene3D G3DSA:3.40.50.300 325 579 2.6E-71 T 29-03-2018 A616_RS23255 12c40fac8b1aa0b1e29eb2a8314844e5 143 Pfam PF06841 T4-like virus tail tube protein gp19 9 140 3.6E-47 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 A616_RS23255 12c40fac8b1aa0b1e29eb2a8314844e5 143 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 141 7.4E-48 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 Gene3D G3DSA:3.30.930.10 1 324 2.8E-69 T 29-03-2018 A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 Pfam PF03129 Anticodon binding domain 332 420 6.8E-17 T 29-03-2018 IPR004154 Anticodon-binding A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 Gene3D G3DSA:3.40.50.800 325 424 9.1E-21 T 29-03-2018 IPR004154 Anticodon-binding A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 SUPERFAMILY SSF52954 329 419 5.13E-26 T 29-03-2018 IPR004154 Anticodon-binding A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 PIRSF PIRSF001549 1 422 6.1E-116 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 SUPERFAMILY SSF55681 4 320 1.01E-93 T 29-03-2018 A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 Pfam PF13393 Histidyl-tRNA synthetase 9 313 1.0E-46 T 29-03-2018 A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 420 32.897 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A616_RS10765 9ffdc055e9d79ddbb490834520c8c8b2 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 410 2.2E-149 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 PIRSF PIRSF000429 1 399 1.4E-140 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 SUPERFAMILY SSF53901 5 276 8.52E-86 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 397 2.4E-149 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 Pfam PF00108 Thiolase, N-terminal domain 5 268 2.7E-85 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 Gene3D G3DSA:3.40.47.10 272 396 8.8E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 Pfam PF02803 Thiolase, C-terminal domain 276 398 1.3E-51 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 Gene3D G3DSA:3.40.47.10 1 271 2.5E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS27485 f573e3334dea4c828a434a9d7f2de2d0 399 SUPERFAMILY SSF53901 277 398 2.37E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS09365 5dff9f6223d0fae0c3beed8b7f081cea 150 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 65 141 2.9E-40 T 29-03-2018 IPR014099 Spore coat protein GerQ A616_RS09365 5dff9f6223d0fae0c3beed8b7f081cea 150 Pfam PF09671 Spore coat protein (Spore_GerQ) 65 140 2.8E-39 T 29-03-2018 IPR014099 Spore coat protein GerQ A616_RS09365 5dff9f6223d0fae0c3beed8b7f081cea 150 PIRSF PIRSF038931 1 148 4.2E-49 T 29-03-2018 IPR014099 Spore coat protein GerQ A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 Gene3D G3DSA:3.40.190.10 87 175 4.6E-17 T 29-03-2018 A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 SUPERFAMILY SSF53850 88 292 2.09E-43 T 29-03-2018 A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 Pfam PF03466 LysR substrate binding domain 87 292 9.3E-44 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 Gene3D G3DSA:1.10.10.10 1 83 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.0E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 SUPERFAMILY SSF46785 1 87 5.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 Gene3D G3DSA:3.40.190.10 176 264 2.3E-20 T 29-03-2018 A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09060 f166a404d7b2143e1800d5819df7406a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Pfam PF01627 Hpt domain 5 95 2.8E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 401 540 3.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SUPERFAMILY SSF55874 355 539 1.44E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Gene3D G3DSA:3.30.565.10 355 542 2.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SMART SM00073 3 100 1.0E-32 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Pfam PF07194 P2 response regulator binding domain 175 253 1.0E-26 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SMART SM01231 293 353 1.7E-19 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SMART SM00387 398 541 1.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Pfam PF01584 CheW-like domain 546 673 5.2E-26 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SUPERFAMILY SSF47384 294 354 6.28E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Gene3D G3DSA:2.30.30.40 620 673 1.5E-21 T 29-03-2018 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Gene3D G3DSA:1.10.287.560 293 354 5.8E-20 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SMART SM00260 533 673 2.1E-40 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SUPERFAMILY SSF55052 171 254 1.62E-24 T 29-03-2018 IPR015162 CheY binding A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SUPERFAMILY SSF50341 540 673 4.58E-33 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 SUPERFAMILY SSF47226 2 125 2.75E-31 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Gene3D G3DSA:2.40.50.180 564 619 2.3E-11 T 29-03-2018 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 294 352 4.0E-16 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 457 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 519 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 538 1.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Gene3D G3DSA:3.30.70.1110 173 252 6.0E-26 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A616_RS19925 186d99aeb87ef6265498c39797cdda0e 674 Gene3D G3DSA:1.20.120.160 1 154 3.4E-32 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 SUPERFAMILY SSF52777 16 238 6.45E-28 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Gene3D G3DSA:3.30.300.30 671 787 1.5E-38 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Gene3D G3DSA:2.30.38.10 585 666 3.5E-22 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 SUPERFAMILY SSF47336 774 848 7.33E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 ProSitePatterns PS00455 Putative AMP-binding domain signature. 414 425 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Pfam PF13193 AMP-binding enzyme C-terminal domain 684 755 1.2E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 296 700 1.5E-124 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Gene3D G3DSA:3.40.50.980 421 584 9.8E-41 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Gene3D G3DSA:3.40.50.980 267 420 5.4E-39 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 SUPERFAMILY SSF56801 232 795 6.93E-154 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Pfam PF00668 Condensation domain 10 255 7.0E-30 T 29-03-2018 IPR001242 Condensation domain A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Gene3D G3DSA:1.10.1200.10 788 863 7.3E-16 T 29-03-2018 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Pfam PF00501 AMP-binding enzyme 276 676 1.7E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18515 cbd0c2081b61e2d9e8dc23225bbd454f 895 Pfam PF00550 Phosphopantetheine attachment site 783 847 6.8E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS06195 995629414c4fc5ce752cdbc2af7ec495 182 Gene3D G3DSA:1.10.287.1080 77 167 4.9E-4 T 29-03-2018 A616_RS06195 995629414c4fc5ce752cdbc2af7ec495 182 Gene3D G3DSA:1.10.260.40 1 75 6.7E-5 T 29-03-2018 A616_RS06195 995629414c4fc5ce752cdbc2af7ec495 182 SUPERFAMILY SSF47413 2 58 7.19E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS12720 452716f5ee3a9b3d1cb10a05187265ca 114 Pfam PF08868 YugN-like family 8 89 2.2E-17 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS12720 452716f5ee3a9b3d1cb10a05187265ca 114 Gene3D G3DSA:3.30.310.100 1 114 9.1E-33 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS12720 452716f5ee3a9b3d1cb10a05187265ca 114 SUPERFAMILY SSF160755 1 111 1.1E-33 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 SUPERFAMILY SSF53850 90 284 9.31E-35 T 29-03-2018 A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 Gene3D G3DSA:3.40.190.10 175 258 2.8E-17 T 29-03-2018 A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 Gene3D G3DSA:1.10.10.10 1 82 1.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 Pfam PF03466 LysR substrate binding domain 89 280 1.0E-34 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 SUPERFAMILY SSF46785 1 111 6.33E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23860 fa96dfe376b4a2d4961e5edfcd621217 293 Gene3D G3DSA:3.40.190.10 91 174 9.6E-22 T 29-03-2018 A616_RS09790 88f55f2e5ef1736221115966f235b949 249 SUPERFAMILY SSF46548 113 240 4.36E-28 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS09790 88f55f2e5ef1736221115966f235b949 249 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 116 3.3E-29 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09790 88f55f2e5ef1736221115966f235b949 249 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 10 233 2.5E-40 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09790 88f55f2e5ef1736221115966f235b949 249 SUPERFAMILY SSF54292 3 111 1.36E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS09790 88f55f2e5ef1736221115966f235b949 249 Gene3D G3DSA:1.10.1060.10 112 248 1.6E-19 T 29-03-2018 A616_RS09790 88f55f2e5ef1736221115966f235b949 249 Pfam PF13183 4Fe-4S dicluster domain 150 225 1.6E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS09790 88f55f2e5ef1736221115966f235b949 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS09790 88f55f2e5ef1736221115966f235b949 249 Gene3D G3DSA:3.10.20.30 1 111 2.2E-24 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS24720 0383f543c9b44444f512f8a49976d852 286 SMART SM00849 21 222 8.8E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS24720 0383f543c9b44444f512f8a49976d852 286 Gene3D G3DSA:3.60.15.10 1 244 3.6E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS24720 0383f543c9b44444f512f8a49976d852 286 Pfam PF00753 Metallo-beta-lactamase superfamily 28 189 4.4E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS24720 0383f543c9b44444f512f8a49976d852 286 SUPERFAMILY SSF56281 5 276 6.55E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS27765 1a6b3a616eddf141ec96b63e4c1a8cc1 460 SUPERFAMILY SSF53098 123 298 1.33E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS27765 1a6b3a616eddf141ec96b63e4c1a8cc1 460 SUPERFAMILY SSF48452 302 426 5.69E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS27765 1a6b3a616eddf141ec96b63e4c1a8cc1 460 Gene3D G3DSA:3.30.420.10 123 454 4.6E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS27765 1a6b3a616eddf141ec96b63e4c1a8cc1 460 Pfam PF13482 RNase_H superfamily 124 294 6.6E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 SUPERFAMILY SSF53850 89 289 1.18E-32 T 29-03-2018 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 Gene3D G3DSA:1.10.10.10 1 83 6.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 SUPERFAMILY SSF46785 1 86 3.29E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 Pfam PF03466 LysR substrate binding domain 92 287 4.2E-32 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 Gene3D G3DSA:3.40.190.10 174 256 1.2E-13 T 29-03-2018 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 Gene3D G3DSA:3.40.190.10 89 173 1.8E-15 T 29-03-2018 A616_RS12620 ee80e9870b8d8faab31ef8e5143b77fa 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 PIRSF PIRSF000521 34 453 1.8E-38 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 Gene3D G3DSA:3.40.640.10 197 330 1.7E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 Gene3D G3DSA:3.90.1150.10 5 176 1.4E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 Gene3D G3DSA:3.90.1150.10 331 454 8.8E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 Pfam PF00202 Aminotransferase class-III 32 449 4.8E-112 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS18765 999b2601e183a7cf9c1b4eb9ffb0d336 454 SUPERFAMILY SSF53383 22 452 6.54E-128 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 SUPERFAMILY SSF55846 27 165 1.96E-30 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 SMART SM00701 8 142 9.7E-8 T 29-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 Gene3D G3DSA:3.30.457.10 241 269 0.57 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 Gene3D G3DSA:3.30.457.10 200 240 2.2E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 Gene3D G3DSA:3.40.80.10 13 168 8.0E-34 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 SUPERFAMILY SSF55383 201 261 2.75E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 Pfam PF07833 Copper amine oxidase N-terminal domain 197 232 6.1E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 SMART SM00644 22 151 1.3E-11 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS06475 d86bb66709eefdaf999b2cc38c40d6e1 270 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 32 150 9.7E-22 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 Gene3D G3DSA:3.40.710.10 38 303 5.2E-33 T 29-03-2018 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 Pfam PF13354 Beta-lactamase enzyme family 67 272 4.0E-38 T 29-03-2018 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 ProSitePatterns PS00146 Beta-lactamase class-A active site. 79 94 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 117 142 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 153 177 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 46 70 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 179 204 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 215 230 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 77 94 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 PRINTS PR00118 Beta-lactamase class A signature 232 247 1.1E-65 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 A616_RS07115 2686a23e28f7ee196ef9eda8f2ca2bbc 304 SUPERFAMILY SSF56601 43 299 1.71E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS27150 043bc00f98350cdcf77cd1916c6ef910 263 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 19 222 3.3E-44 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 A616_RS27150 043bc00f98350cdcf77cd1916c6ef910 263 Pfam PF02361 Cobalt transport protein 14 226 2.0E-31 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A616_RS00165 4a2d9c58ae2d539a1d6d1978c31da2cc 424 Gene3D G3DSA:1.20.1250.20 226 416 2.1E-20 T 29-03-2018 A616_RS00165 4a2d9c58ae2d539a1d6d1978c31da2cc 424 SUPERFAMILY SSF103473 8 413 5.49E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS00165 4a2d9c58ae2d539a1d6d1978c31da2cc 424 Gene3D G3DSA:1.20.1250.20 1 218 2.4E-27 T 29-03-2018 A616_RS00165 4a2d9c58ae2d539a1d6d1978c31da2cc 424 Pfam PF07690 Major Facilitator Superfamily 20 345 1.2E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 PRINTS PR00723 Subtilisin serine protease family (S8) signature 96 115 6.5E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 PRINTS PR00723 Subtilisin serine protease family (S8) signature 282 298 6.5E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 PRINTS PR00723 Subtilisin serine protease family (S8) signature 129 142 6.5E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 Gene3D G3DSA:3.40.50.200 58 303 6.2E-75 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 Pfam PF00082 Subtilase family 96 297 1.7E-43 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 SUPERFAMILY SSF52743 78 298 6.02E-76 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 283 293 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 133 143 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A616_RS12600 8b4f6a11ed4a3bdd70b1b8cc85a2899b 304 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 101 112 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A616_RS02125 c16477005246f05e233954d8a61aa9de 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 124 1.5E-9 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A616_RS02125 c16477005246f05e233954d8a61aa9de 382 Pfam PF13378 Enolase C-terminal domain-like 148 355 2.3E-45 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS02125 c16477005246f05e233954d8a61aa9de 382 SUPERFAMILY SSF51604 112 363 1.83E-65 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS02125 c16477005246f05e233954d8a61aa9de 382 SUPERFAMILY SSF54826 1 125 8.36E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS02125 c16477005246f05e233954d8a61aa9de 382 Gene3D G3DSA:3.20.20.120 136 350 5.2E-58 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS02125 c16477005246f05e233954d8a61aa9de 382 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 361 43.184 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS02125 c16477005246f05e233954d8a61aa9de 382 SMART SM00922 142 235 9.6E-22 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A616_RS02125 c16477005246f05e233954d8a61aa9de 382 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 332 1.0E-106 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS02125 c16477005246f05e233954d8a61aa9de 382 Gene3D G3DSA:3.30.390.10 1 135 1.3E-26 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 Gene3D G3DSA:1.10.357.10 68 212 1.4E-18 T 29-03-2018 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 SUPERFAMILY SSF48498 88 212 6.23E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 SUPERFAMILY SSF46689 15 85 7.7E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.6E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 8.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 8.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 Gene3D G3DSA:1.10.10.60 9 67 8.8E-14 T 29-03-2018 A616_RS25640 47bec3fbcc873eafcbf04046e89962b8 218 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS13270 a6617472bdc738923036496726a906e9 473 SUPERFAMILY SSF51905 2 344 3.77E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 PIRSF PIRSF000350 1 471 1.8E-83 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 Gene3D G3DSA:1.10.287.990 36 104 2.9E-22 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 Gene3D G3DSA:3.50.50.60 283 367 2.0E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 207 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 155 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 1.9E-67 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 5.4E-175 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A616_RS13270 a6617472bdc738923036496726a906e9 473 Gene3D G3DSA:3.50.50.60 123 259 2.8E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 Gene3D G3DSA:3.30.390.30 368 473 6.8E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 SUPERFAMILY SSF55424 350 472 7.9E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.3E-34 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 1.3E-34 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.3E-34 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-34 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 1.3E-34 T 29-03-2018 A616_RS13270 a6617472bdc738923036496726a906e9 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 8.1E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A616_RS13270 a6617472bdc738923036496726a906e9 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 3.6E-36 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A616_RS20225 c002a47a0862b82526850cf463dd3809 243 PIRSF PIRSF000386 1 243 2.6E-106 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A616_RS20225 c002a47a0862b82526850cf463dd3809 243 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 243 115.019 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A616_RS20225 c002a47a0862b82526850cf463dd3809 243 Gene3D G3DSA:3.40.1280.10 1 167 1.4E-77 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS20225 c002a47a0862b82526850cf463dd3809 243 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 232 2.9E-102 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A616_RS20225 c002a47a0862b82526850cf463dd3809 243 Gene3D G3DSA:1.10.1270.20 168 243 8.4E-38 T 29-03-2018 A616_RS20225 c002a47a0862b82526850cf463dd3809 243 SUPERFAMILY SSF75217 1 241 1.05E-102 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS20225 c002a47a0862b82526850cf463dd3809 243 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 219 7.9E-73 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A616_RS18330 f2a885b988634aec5340bbc85333e31b 216 Pfam PF14187 Domain of unknown function (DUF4310) 6 213 2.3E-107 T 29-03-2018 IPR025456 Protein of unknown function DUF4310 A616_RS18330 f2a885b988634aec5340bbc85333e31b 216 TIGRFAM TIGR03579 EF_0833: conserved hypothetical protein EF_0833/AHA_3914 7 213 9.8E-103 T 29-03-2018 IPR025456 Protein of unknown function DUF4310 A616_RS15910 e087338b4ce2c43d782ec40af39cd1ee 340 Gene3D G3DSA:1.10.1660.10 82 157 1.8E-5 T 29-03-2018 A616_RS15910 e087338b4ce2c43d782ec40af39cd1ee 340 SMART SM00422 26 95 2.2E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS15910 e087338b4ce2c43d782ec40af39cd1ee 340 Gene3D G3DSA:1.10.1660.10 23 81 3.6E-20 T 29-03-2018 A616_RS15910 e087338b4ce2c43d782ec40af39cd1ee 340 SUPERFAMILY SSF46955 27 128 1.79E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS15910 e087338b4ce2c43d782ec40af39cd1ee 340 Pfam PF13411 MerR HTH family regulatory protein 28 93 2.9E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27830 98474b4910aa2da324166502fd60abc7 195 Gene3D G3DSA:1.10.357.10 1 195 5.9E-27 T 29-03-2018 A616_RS27830 98474b4910aa2da324166502fd60abc7 195 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 83 194 3.4E-21 T 29-03-2018 A616_RS27830 98474b4910aa2da324166502fd60abc7 195 SUPERFAMILY SSF46689 3 78 4.44E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS27830 98474b4910aa2da324166502fd60abc7 195 SUPERFAMILY SSF48498 82 194 1.4E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS27830 98474b4910aa2da324166502fd60abc7 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27830 98474b4910aa2da324166502fd60abc7 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27830 98474b4910aa2da324166502fd60abc7 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS27830 98474b4910aa2da324166502fd60abc7 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 2.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS06630 3e31855ec70345811b2586d36b4df074 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 249 3.2E-73 T 29-03-2018 A616_RS06630 3e31855ec70345811b2586d36b4df074 251 SUPERFAMILY SSF51735 5 250 7.15E-88 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS06630 3e31855ec70345811b2586d36b4df074 251 Gene3D G3DSA:3.40.50.720 1 42 2.2E-10 T 29-03-2018 A616_RS06630 3e31855ec70345811b2586d36b4df074 251 Gene3D G3DSA:3.40.50.720 43 251 1.9E-69 T 29-03-2018 A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 6.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06630 3e31855ec70345811b2586d36b4df074 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0016 T 29-03-2018 A616_RS06630 3e31855ec70345811b2586d36b4df074 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS26625 9fffba31fa3dd630b7da2365d2ac7bdc 364 TIGRFAM TIGR00277 HDIG: HDIG domain 135 212 1.2E-7 T 29-03-2018 IPR006675 HDIG domain A616_RS26625 9fffba31fa3dd630b7da2365d2ac7bdc 364 Gene3D G3DSA:1.10.3210.10 108 300 2.7E-46 T 29-03-2018 A616_RS26625 9fffba31fa3dd630b7da2365d2ac7bdc 364 SUPERFAMILY SSF109604 126 296 6.04E-39 T 29-03-2018 A616_RS26625 9fffba31fa3dd630b7da2365d2ac7bdc 364 Pfam PF01966 HD domain 137 258 5.5E-21 T 29-03-2018 IPR006674 HD domain A616_RS26625 9fffba31fa3dd630b7da2365d2ac7bdc 364 SMART SM00471 132 268 6.4E-12 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS07240 a26c8c73ba9f1d32f1f492fd39e7fe2c 524 Gene3D G3DSA:3.20.20.70 100 520 3.9E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS07240 a26c8c73ba9f1d32f1f492fd39e7fe2c 524 PIRSF PIRSF006429 1 523 1.9E-136 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein A616_RS07240 a26c8c73ba9f1d32f1f492fd39e7fe2c 524 Pfam PF01645 Conserved region in glutamate synthase 156 490 1.1E-81 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A616_RS07240 a26c8c73ba9f1d32f1f492fd39e7fe2c 524 SUPERFAMILY SSF51395 161 518 6.74E-97 T 29-03-2018 A616_RS07240 a26c8c73ba9f1d32f1f492fd39e7fe2c 524 SUPERFAMILY SSF51395 8 115 6.74E-97 T 29-03-2018 A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 SUPERFAMILY SSF88946 3 105 2.04E-28 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 174 6.1E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 Pfam PF04545 Sigma-70, region 4 125 172 4.9E-12 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 Gene3D G3DSA:1.10.10.10 101 181 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 Gene3D G3DSA:1.10.1740.10 1 100 1.0E-25 T 29-03-2018 A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 Pfam PF04542 Sigma-70 region 2 23 89 6.3E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04430 a5c98b8d77ec283ec399be3dd9d4d032 185 SUPERFAMILY SSF88659 93 175 2.43E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09605 cea76089e7f98e3ce6ada68d71f0a113 136 Pfam PF03994 Domain of Unknown Function (DUF350) 80 134 2.3E-11 T 29-03-2018 IPR007140 Protein of unknown function DUF350 A616_RS09605 cea76089e7f98e3ce6ada68d71f0a113 136 Pfam PF03994 Domain of Unknown Function (DUF350) 15 68 7.5E-14 T 29-03-2018 IPR007140 Protein of unknown function DUF350 A616_RS11360 a62307af1b5c0990330ead7d4f86003e 216 Pfam PF08348 YheO-like PAS domain 8 122 1.1E-41 T 29-03-2018 IPR013559 YheO-like A616_RS11360 a62307af1b5c0990330ead7d4f86003e 216 Gene3D G3DSA:1.10.10.60 152 214 4.0E-5 T 29-03-2018 A616_RS11360 a62307af1b5c0990330ead7d4f86003e 216 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 7 113 2.0E-24 T 29-03-2018 IPR013559 YheO-like A616_RS11360 a62307af1b5c0990330ead7d4f86003e 216 Pfam PF13309 HTH domain 150 212 2.8E-24 T 29-03-2018 A616_RS02335 067ebdebf697cdd263a9a00b680eb701 196 Gene3D G3DSA:1.10.10.60 4 54 7.6E-13 T 29-03-2018 A616_RS02335 067ebdebf697cdd263a9a00b680eb701 196 Gene3D G3DSA:1.10.357.10 55 191 8.3E-7 T 29-03-2018 A616_RS02335 067ebdebf697cdd263a9a00b680eb701 196 SUPERFAMILY SSF46689 5 75 6.67E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02335 067ebdebf697cdd263a9a00b680eb701 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 PIRSF PIRSF005963 1 300 1.7E-135 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 SUPERFAMILY SSF102114 21 283 2.22E-63 T 29-03-2018 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 Pfam PF04055 Radical SAM superfamily 61 221 2.1E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 Gene3D G3DSA:3.20.20.70 11 268 1.6E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 285 1.3E-117 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 SMART SM00729 54 259 7.3E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 Hamap MF_00206 Lipoyl synthase [lipA]. 1 294 145.623 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A616_RS26480 67546fe83d4da780c4497f633765cc14 300 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 4 43 3.4E-7 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 Pfam PF08241 Methyltransferase domain 183 276 1.4E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 SUPERFAMILY SSF53335 141 331 1.67E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.3E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 Gene3D G3DSA:1.10.1660.10 56 142 1.1E-6 T 29-03-2018 A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 SMART SM00422 1 70 3.5E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 SUPERFAMILY SSF46955 1 113 8.79E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 Gene3D G3DSA:3.40.50.150 143 342 5.1E-35 T 29-03-2018 A616_RS12730 ead8ded5dbb5d79fbca2d727d62538e9 345 Gene3D G3DSA:1.10.1660.10 1 55 1.6E-20 T 29-03-2018 A616_RS03890 60a7381ce63ee642d328dbef7394d73c 351 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 225 335 3.9E-25 T 29-03-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain A616_RS03890 60a7381ce63ee642d328dbef7394d73c 351 SUPERFAMILY SSF159774 53 345 1.23E-92 T 29-03-2018 IPR023158 YerB-like A616_RS03890 60a7381ce63ee642d328dbef7394d73c 351 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 58 197 6.7E-50 T 29-03-2018 IPR021416 Protein of unknown function DUF3048, N-terminal A616_RS03890 60a7381ce63ee642d328dbef7394d73c 351 Gene3D G3DSA:3.50.90.10 40 350 1.1E-101 T 29-03-2018 IPR023158 YerB-like A616_RS19130 a80803fc5c875c95680317163392f52e 326 Gene3D G3DSA:3.90.25.10 169 326 8.3E-12 T 29-03-2018 A616_RS19130 a80803fc5c875c95680317163392f52e 326 Gene3D G3DSA:3.40.50.720 3 159 1.1E-17 T 29-03-2018 A616_RS19130 a80803fc5c875c95680317163392f52e 326 SUPERFAMILY SSF51735 6 322 1.3E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS19130 a80803fc5c875c95680317163392f52e 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 222 3.6E-14 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 Gene3D G3DSA:1.25.40.10 178 371 1.2E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 SMART SM00028 326 359 1.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 SMART SM00028 281 314 0.16 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 SUPERFAMILY SSF53448 2 152 2.19E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 Pfam PF07719 Tetratricopeptide repeat 328 358 3.7E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 SUPERFAMILY SSF48452 257 369 1.3E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 Pfam PF00535 Glycosyl transferase family 2 8 111 2.4E-21 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS31615 d7b23e588748377ac7352065ccbd98ed 382 Gene3D G3DSA:3.90.550.10 1 175 2.5E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS20385 d2205fe96b31244e5f36a69bafc9e890 109 Gene3D G3DSA:3.30.429.10 2 101 4.2E-23 T 29-03-2018 A616_RS20385 d2205fe96b31244e5f36a69bafc9e890 109 SUPERFAMILY SSF55331 2 100 1.54E-19 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily A616_RS20385 d2205fe96b31244e5f36a69bafc9e890 109 Pfam PF08921 Domain of unknown function (DUF1904) 2 100 1.5E-23 T 29-03-2018 IPR015017 Protein of unknown function DUF1904 A616_RS24620 cfe61bef9d10b6b70e34efa48012b812 406 Gene3D G3DSA:1.20.1250.20 2 195 2.6E-28 T 29-03-2018 A616_RS24620 cfe61bef9d10b6b70e34efa48012b812 406 Pfam PF07690 Major Facilitator Superfamily 10 340 1.0E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24620 cfe61bef9d10b6b70e34efa48012b812 406 Gene3D G3DSA:1.20.1250.20 196 399 1.3E-24 T 29-03-2018 A616_RS24620 cfe61bef9d10b6b70e34efa48012b812 406 SUPERFAMILY SSF103473 5 389 4.71E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 Pfam PF00512 His Kinase A (phospho-acceptor) domain 192 256 7.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 SUPERFAMILY SSF55874 247 408 2.62E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 408 1.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 3.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 367 3.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 3.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 SMART SM00388 191 257 7.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 Gene3D G3DSA:1.10.287.130 181 251 7.2E-11 T 29-03-2018 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 SMART SM00304 131 183 0.0021 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 SUPERFAMILY SSF47384 177 256 4.51E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 Gene3D G3DSA:3.30.565.10 252 408 1.8E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08425 b6cad238783e89121fa3c421cb5b5751 411 SMART SM00387 302 411 3.4E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 SUPERFAMILY SSF103190 85 186 7.85E-12 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Gene3D G3DSA:1.10.287.950 403 656 1.0E-48 T 29-03-2018 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Gene3D G3DSA:3.30.450.20 165 270 6.4E-16 T 29-03-2018 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Gene3D G3DSA:1.10.287.950 295 394 1.1E-7 T 29-03-2018 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 SMART SM00283 378 653 4.3E-59 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 SMART SM00304 296 349 6.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Gene3D G3DSA:3.30.450.20 32 164 4.2E-17 T 29-03-2018 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 SUPERFAMILY SSF58104 384 653 4.58E-59 T 29-03-2018 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 SUPERFAMILY SSF58104 322 351 4.58E-59 T 29-03-2018 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Pfam PF00672 HAMP domain 297 345 7.7E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 591 4.9E-36 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS01800 5f1865c3dbf28fc7f845a030170cb8e0 656 Pfam PF02743 Cache domain 41 239 1.3E-21 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS20765 f5e51e9dea61956d87d3a34e5aef35da 251 Gene3D G3DSA:3.60.40.10 1 242 1.5E-42 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS20765 f5e51e9dea61956d87d3a34e5aef35da 251 Pfam PF13672 Protein phosphatase 2C 11 226 3.3E-22 T 29-03-2018 A616_RS20765 f5e51e9dea61956d87d3a34e5aef35da 251 SUPERFAMILY SSF81606 1 241 2.22E-64 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS20765 f5e51e9dea61956d87d3a34e5aef35da 251 SMART SM00332 1 240 1.2E-22 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS20765 f5e51e9dea61956d87d3a34e5aef35da 251 SMART SM00331 7 242 2.4E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 478 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 512 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 531 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 492 1.5E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 SUPERFAMILY SSF55890 326 395 3.79E-11 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Pfam PF13188 PAS domain 219 265 8.3E-6 T 29-03-2018 IPR000014 PAS domain A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Gene3D G3DSA:3.30.565.10 392 547 7.4E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 SMART SM00387 423 534 3.1E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 SUPERFAMILY SSF55874 391 532 1.05E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Gene3D G3DSA:3.30.450.20 35 175 3.6E-24 T 29-03-2018 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 325 368 3.5E-11 T 29-03-2018 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Gene3D G3DSA:3.30.450.20 215 318 2.5E-11 T 29-03-2018 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 SUPERFAMILY SSF103190 41 172 1.92E-38 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Pfam PF17203 Single cache domain 3 43 173 2.6E-23 T 29-03-2018 IPR033463 Single cache domain 3 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Gene3D G3DSA:1.10.287.130 319 382 3.6E-14 T 29-03-2018 A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 533 2.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23605 cf0d822d13674ab72a8014da3fd406c6 551 SUPERFAMILY SSF55785 213 315 1.79E-7 T 29-03-2018 IPR000014 PAS domain A616_RS00390 f331d01e5a3d0ba9e07148adcce1e3e1 160 Gene3D G3DSA:3.40.140.10 2 160 8.4E-57 T 29-03-2018 A616_RS00390 f331d01e5a3d0ba9e07148adcce1e3e1 160 Pfam PF14437 MafB19-like deaminase 6 152 1.7E-43 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A616_RS00390 f331d01e5a3d0ba9e07148adcce1e3e1 160 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A616_RS00390 f331d01e5a3d0ba9e07148adcce1e3e1 160 SUPERFAMILY SSF53927 5 153 2.51E-60 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS00390 f331d01e5a3d0ba9e07148adcce1e3e1 160 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 11 152 48.893 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A616_RS12785 da76c0086bb3ea7989a1aaec17b98dea 284 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 6 55 9.1E-6 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS12785 da76c0086bb3ea7989a1aaec17b98dea 284 Gene3D G3DSA:1.10.3720.10 8 270 1.7E-40 T 29-03-2018 A616_RS12785 da76c0086bb3ea7989a1aaec17b98dea 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 283 7.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12785 da76c0086bb3ea7989a1aaec17b98dea 284 SUPERFAMILY SSF161098 73 263 8.11E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 SMART SM00354 1 65 6.0E-24 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 42 7.7E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 Gene3D G3DSA:1.10.260.40 1 47 1.5E-20 T 29-03-2018 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 Pfam PF13377 Periplasmic binding protein-like domain 163 323 4.2E-38 T 29-03-2018 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 SUPERFAMILY SSF47413 1 53 1.31E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 SUPERFAMILY SSF53822 54 324 1.24E-79 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 Gene3D G3DSA:3.40.50.2300 48 167 9.0E-31 T 29-03-2018 A616_RS15210 1b06c73d704bf07fed5a51db8a612521 328 Gene3D G3DSA:3.40.50.2300 168 303 7.6E-44 T 29-03-2018 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 SUPERFAMILY SSF90123 11 296 4.19E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 SMART SM00382 365 566 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 Pfam PF00664 ABC transporter transmembrane region 17 277 8.1E-20 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 13 546 8.9E-164 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 Pfam PF00005 ABC transporter 367 505 1.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 Gene3D G3DSA:1.20.1560.10 4 320 1.4E-32 T 29-03-2018 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 SUPERFAMILY SSF52540 335 573 8.74E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 Gene3D G3DSA:3.40.50.300 321 580 4.9E-61 T 29-03-2018 A616_RS25405 96ef924cdfed45d014ce73a4044af8a7 581 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04285 0bb37a2830562d71c468a8cd1ec61c1f 147 Pfam PF07486 Cell Wall Hydrolase 24 133 4.7E-18 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A616_RS27145 6b3fc89c87cd3284afb9ab6811735d1d 282 Pfam PF00005 ABC transporter 23 171 3.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27145 6b3fc89c87cd3284afb9ab6811735d1d 282 SMART SM00382 32 219 0.0012 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27145 6b3fc89c87cd3284afb9ab6811735d1d 282 SUPERFAMILY SSF52540 5 233 2.77E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27145 6b3fc89c87cd3284afb9ab6811735d1d 282 Gene3D G3DSA:3.40.50.300 1 243 1.1E-61 T 29-03-2018 A616_RS27145 6b3fc89c87cd3284afb9ab6811735d1d 282 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 Gene3D G3DSA:2.40.110.10 114 211 8.3E-14 T 29-03-2018 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 PIRSF PIRSF016578 53 94 4.5 T 29-03-2018 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 PIRSF PIRSF016578 134 389 3.3E-13 T 29-03-2018 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 Gene3D G3DSA:1.20.140.10 212 390 5.3E-19 T 29-03-2018 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 380 8.8E-10 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 SUPERFAMILY SSF47203 236 384 9.02E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS28920 d396ffeaa3a6556d605c38ee6d489103 392 SUPERFAMILY SSF56645 60 222 1.7E-22 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 SUPERFAMILY SSF53697 5 448 1.33E-138 T 29-03-2018 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 Gene3D G3DSA:3.40.50.10490 64 208 7.4E-46 T 29-03-2018 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 2.2E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 2.2E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 2.2E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 2.2E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 2.2E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 2.2E-26 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 Gene3D G3DSA:3.40.50.10490 209 435 8.3E-70 T 29-03-2018 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 2 436 25.946 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 Pfam PF00342 Phosphoglucose isomerase 77 296 3.1E-18 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 455 502 9.0E-11 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A616_RS05090 8a7dc132b669119b6352ee693a9294e6 529 Gene3D G3DSA:3.40.50.10490 1 63 4.0E-8 T 29-03-2018 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 SUPERFAMILY SSF51366 9 239 4.4E-70 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 63 76 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 11 235 6.7E-45 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 12 235 1.0E-56 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 Gene3D G3DSA:3.20.20.70 8 241 1.7E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 SMART SM00934 11 236 2.3E-82 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS20995 f26059125bd3b18f8837ba7372ac3835 245 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 9 241 37.413 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS12200 8408a037c49b2b942eea4855efefe722 371 Pfam PF08756 YfkB-like domain 219 369 2.2E-74 T 29-03-2018 IPR014866 YfkB-like domain A616_RS12200 8408a037c49b2b942eea4855efefe722 371 Gene3D G3DSA:3.20.20.70 27 345 1.6E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS12200 8408a037c49b2b942eea4855efefe722 371 Pfam PF04055 Radical SAM superfamily 36 188 9.7E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS12200 8408a037c49b2b942eea4855efefe722 371 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 10 369 2.2E-186 T 29-03-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB A616_RS12200 8408a037c49b2b942eea4855efefe722 371 SUPERFAMILY SSF102114 30 320 4.12E-30 T 29-03-2018 A616_RS14795 1a027d477797831f49dfdb05950c1b6b 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 465 1.1E-82 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS14795 1a027d477797831f49dfdb05950c1b6b 542 Gene3D G3DSA:3.90.76.10 51 209 2.9E-35 T 29-03-2018 A616_RS14795 1a027d477797831f49dfdb05950c1b6b 542 PIRSF PIRSF002741 1 533 6.0E-120 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS14795 1a027d477797831f49dfdb05950c1b6b 542 Gene3D G3DSA:3.40.190.10 210 303 4.1E-25 T 29-03-2018 A616_RS14795 1a027d477797831f49dfdb05950c1b6b 542 Gene3D G3DSA:3.10.105.10 304 516 3.4E-56 T 29-03-2018 A616_RS14795 1a027d477797831f49dfdb05950c1b6b 542 SUPERFAMILY SSF53850 35 529 2.05E-133 T 29-03-2018 A616_RS02155 002fc10a2b706a5a0e7d6595adeb5f89 391 Pfam PF07690 Major Facilitator Superfamily 10 321 1.4E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS02155 002fc10a2b706a5a0e7d6595adeb5f89 391 SUPERFAMILY SSF103473 4 377 3.27E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02155 002fc10a2b706a5a0e7d6595adeb5f89 391 Gene3D G3DSA:1.20.1250.20 191 378 5.0E-21 T 29-03-2018 A616_RS02155 002fc10a2b706a5a0e7d6595adeb5f89 391 Gene3D G3DSA:1.20.1250.20 1 190 2.8E-24 T 29-03-2018 A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 2.3E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 SMART SM00382 40 231 7.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 Pfam PF00005 ABC transporter 31 181 3.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 Gene3D G3DSA:3.40.50.300 2 323 9.5E-85 T 29-03-2018 A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 SUPERFAMILY SSF52540 5 253 2.54E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16040 b17a7746e271b5f735acde4185f11a91 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 4.6E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS16655 13f9d8cb3a85e6155fd7e4e594ad91a0 166 Gene3D G3DSA:3.40.50.300 1 166 5.5E-24 T 29-03-2018 A616_RS16655 13f9d8cb3a85e6155fd7e4e594ad91a0 166 SUPERFAMILY SSF52540 3 165 6.86E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02790 b0379bd2464634a3dbcc9eb302610a51 250 SUPERFAMILY SSF52540 3 237 1.44E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02790 b0379bd2464634a3dbcc9eb302610a51 250 SMART SM00382 28 222 4.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02790 b0379bd2464634a3dbcc9eb302610a51 250 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 4 250 3.5E-124 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A616_RS02790 b0379bd2464634a3dbcc9eb302610a51 250 Gene3D G3DSA:3.40.50.300 1 248 4.8E-61 T 29-03-2018 A616_RS02790 b0379bd2464634a3dbcc9eb302610a51 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02790 b0379bd2464634a3dbcc9eb302610a51 250 Pfam PF00005 ABC transporter 21 175 1.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS29975 2064d4606ff09664c2ee324f32bd38fc 239 SUPERFAMILY SSF52540 8 213 2.76E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29975 2064d4606ff09664c2ee324f32bd38fc 239 Gene3D G3DSA:3.40.50.300 7 223 2.3E-57 T 29-03-2018 A616_RS29975 2064d4606ff09664c2ee324f32bd38fc 239 PIRSF PIRSF006755 6 233 2.4E-62 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A616_RS29975 2064d4606ff09664c2ee324f32bd38fc 239 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 6 226 29.125 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A616_RS29975 2064d4606ff09664c2ee324f32bd38fc 239 Pfam PF13500 AAA domain 8 212 8.5E-51 T 29-03-2018 A616_RS29975 2064d4606ff09664c2ee324f32bd38fc 239 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 10 177 6.4E-53 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 Gene3D G3DSA:3.40.50.300 219 412 2.4E-39 T 29-03-2018 A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 SUPERFAMILY SSF52540 71 354 2.72E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 Pfam PF00270 DEAD/DEAH box helicase 27 190 4.0E-44 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 SMART SM00490 254 335 8.7E-28 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 SMART SM00487 22 229 7.9E-50 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 SUPERFAMILY SSF52540 19 95 1.31E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 Gene3D G3DSA:3.40.50.300 6 218 2.1E-52 T 29-03-2018 A616_RS18970 0f14c73e6f860e2cf7181fd6c9871c74 414 Pfam PF00271 Helicase conserved C-terminal domain 227 335 5.5E-26 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS12330 d0c334808e22168beb52cab09d6a4ba1 415 SUPERFAMILY SSF103473 7 393 1.26E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS12330 d0c334808e22168beb52cab09d6a4ba1 415 Pfam PF07690 Major Facilitator Superfamily 22 229 1.2E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS12330 d0c334808e22168beb52cab09d6a4ba1 415 Gene3D G3DSA:1.20.1250.20 3 199 1.6E-26 T 29-03-2018 A616_RS12330 d0c334808e22168beb52cab09d6a4ba1 415 Gene3D G3DSA:1.20.1250.20 202 410 4.8E-21 T 29-03-2018 A616_RS02890 4fde1e4100fad168d0f046333e2d83d5 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 6.7E-33 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A616_RS02890 4fde1e4100fad168d0f046333e2d83d5 116 SUPERFAMILY SSF50118 2 113 2.45E-41 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A616_RS02890 4fde1e4100fad168d0f046333e2d83d5 116 PIRSF PIRSF033490 1 113 1.3E-38 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A616_RS02890 4fde1e4100fad168d0f046333e2d83d5 116 Gene3D G3DSA:2.30.30.110 1 116 2.0E-38 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A616_RS28015 686507ec988f8e0772ffd94301b49ce8 167 Pfam PF01479 S4 domain 117 162 2.7E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS28015 686507ec988f8e0772ffd94301b49ce8 167 Gene3D G3DSA:3.10.290.10 100 167 4.4E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS28015 686507ec988f8e0772ffd94301b49ce8 167 SUPERFAMILY SSF55174 112 164 2.62E-8 T 29-03-2018 A616_RS19225 4f8831b1bed065772a998d41778baf78 227 Pfam PF02586 SOS response associated peptidase (SRAP) 1 209 5.8E-68 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) A616_RS19225 4f8831b1bed065772a998d41778baf78 227 SUPERFAMILY SSF143081 2 221 4.58E-76 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) A616_RS19225 4f8831b1bed065772a998d41778baf78 227 Gene3D G3DSA:3.90.1680.10 1 221 2.4E-79 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) A616_RS11170 0376ab7b3e66c250dd69f101cf710213 158 Gene3D G3DSA:3.10.450.50 24 142 0.0011 T 29-03-2018 A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 SUPERFAMILY SSF46689 6 78 1.65E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 Gene3D G3DSA:1.10.10.60 3 50 3.7E-20 T 29-03-2018 A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.2E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.2E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 Gene3D G3DSA:1.10.10.60 51 183 2.2E-11 T 29-03-2018 A616_RS04375 79254b8c8c50a0dbc2fa897da04f15c4 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 7.0E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 375 6.9E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 356 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 374 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 323 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 337 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 SUPERFAMILY SSF55874 222 378 4.85E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 SMART SM00387 270 377 3.0E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 SUPERFAMILY SSF47384 158 224 1.73E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 Gene3D G3DSA:1.10.287.130 143 224 1.2E-10 T 29-03-2018 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 SMART SM00388 162 228 1.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 Pfam PF00512 His Kinase A (phospho-acceptor) domain 162 224 3.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS22645 b6cfea9ef4db0dceac65e1a7643238e8 388 Gene3D G3DSA:3.30.565.10 232 383 3.5E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 Gene3D G3DSA:1.10.287.130 284 340 8.5E-20 T 29-03-2018 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 SMART SM00388 294 360 5.0E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 406 512 3.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 SMART SM00387 406 515 6.4E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 SUPERFAMILY SSF47384 277 361 2.35E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 Pfam PF00512 His Kinase A (phospho-acceptor) domain 294 360 5.4E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 SUPERFAMILY SSF158472 238 290 5.1E-6 T 29-03-2018 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 SMART SM00304 238 293 1.6E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 469 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 493 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 455 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 512 4.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 Gene3D G3DSA:3.30.565.10 341 512 2.5E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 Pfam PF00672 HAMP domain 238 288 1.4E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS30785 e96c9b5c5f48f717dbecf4cec793797d 518 SUPERFAMILY SSF55874 349 511 2.62E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 Gene3D G3DSA:3.40.1390.30 2 124 5.1E-36 T 29-03-2018 A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 Gene3D G3DSA:3.30.70.120 132 222 2.2E-42 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 PIRSF PIRSF037489 1 371 1.2E-151 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 Gene3D G3DSA:3.40.1390.30 223 359 8.8E-20 T 29-03-2018 A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 SUPERFAMILY SSF102705 6 370 3.14E-129 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 365 2.3E-76 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A616_RS11715 ee239db7151e7e226b8ecf6a573d5717 371 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 350 1.2E-79 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A616_RS03015 bc7b3ffdaa0ad77a321aec26621e3727 439 Pfam PF00188 Cysteine-rich secretory protein family 322 429 1.1E-17 T 29-03-2018 IPR014044 CAP domain A616_RS03015 bc7b3ffdaa0ad77a321aec26621e3727 439 Gene3D G3DSA:3.30.1450.10 142 202 3.9E-6 T 29-03-2018 A616_RS03015 bc7b3ffdaa0ad77a321aec26621e3727 439 Pfam PF14504 CAP-associated N-terminal 150 287 7.3E-38 T 29-03-2018 IPR029410 CAP-associated domain A616_RS03015 bc7b3ffdaa0ad77a321aec26621e3727 439 SUPERFAMILY SSF55797 314 434 4.01E-23 T 29-03-2018 IPR014044 CAP domain A616_RS03015 bc7b3ffdaa0ad77a321aec26621e3727 439 Gene3D G3DSA:3.40.33.10 309 438 1.2E-18 T 29-03-2018 IPR014044 CAP domain A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 SUPERFAMILY SSF55874 198 364 2.62E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 SUPERFAMILY SSF47384 127 207 9.22E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 SMART SM00387 255 366 2.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 Gene3D G3DSA:3.30.565.10 213 368 4.7E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 365 2.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 7.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 320 7.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 7.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 306 7.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 Gene3D G3DSA:1.10.287.130 132 205 4.0E-17 T 29-03-2018 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 SMART SM00388 142 209 9.7E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31070 aae35a21ffb0077dca282522e486e2f6 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 142 206 6.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 SUPERFAMILY SSF53738 31 239 1.18E-40 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Gene3D G3DSA:3.30.310.50 471 577 1.1E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 45 179 2.5E-35 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 521 561 1.9E-7 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Gene3D G3DSA:3.40.120.10 340 453 1.2E-36 T 29-03-2018 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Gene3D G3DSA:3.40.120.10 18 215 2.3E-49 T 29-03-2018 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 SUPERFAMILY SSF55957 447 485 2.35E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 SUPERFAMILY SSF55957 517 576 2.35E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 SUPERFAMILY SSF53738 211 318 3.18E-19 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 328 454 1.4E-22 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 SUPERFAMILY SSF53738 308 458 3.1E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 213 316 7.0E-21 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 300 315 9.3E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 141 155 9.3E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS10130 6f212d4d72ce9ed48e2baae89a71bc4b 578 Gene3D G3DSA:3.40.120.10 216 339 8.6E-29 T 29-03-2018 A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 SMART SM00382 365 551 2.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 SUPERFAMILY SSF52540 329 575 6.16E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 Gene3D G3DSA:1.20.1560.10 4 326 3.6E-67 T 29-03-2018 A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 Pfam PF00664 ABC transporter transmembrane region 22 292 9.0E-51 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 Gene3D G3DSA:3.40.50.300 327 580 2.7E-75 T 29-03-2018 A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 SUPERFAMILY SSF90123 6 322 7.19E-72 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 Pfam PF00005 ABC transporter 358 505 1.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS01790 3733ba36a539a16c19bd4528e601c85a 583 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS26000 9b3e65054577ff7448285230b812cef1 417 Gene3D G3DSA:1.20.1250.20 206 398 6.2E-14 T 29-03-2018 A616_RS26000 9b3e65054577ff7448285230b812cef1 417 SUPERFAMILY SSF103473 6 399 7.98E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS26000 9b3e65054577ff7448285230b812cef1 417 Gene3D G3DSA:1.20.1250.20 1 198 9.6E-19 T 29-03-2018 A616_RS26000 9b3e65054577ff7448285230b812cef1 417 Pfam PF07690 Major Facilitator Superfamily 13 358 9.2E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 Gene3D G3DSA:1.10.10.60 6 65 6.0E-18 T 29-03-2018 A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 SUPERFAMILY SSF48498 89 195 8.58E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 4.5E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 SUPERFAMILY SSF46689 11 78 6.48E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 7.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24035 fd78ff09b1dc0f4499280bd91952b456 200 Gene3D G3DSA:1.10.357.10 66 198 2.1E-11 T 29-03-2018 A616_RS31180 fab5a74b944e9b2fe2f595a7482f6d61 329 Gene3D G3DSA:3.40.50.1980 163 328 1.8E-35 T 29-03-2018 A616_RS31180 fab5a74b944e9b2fe2f595a7482f6d61 329 Gene3D G3DSA:3.40.50.1980 34 162 1.5E-31 T 29-03-2018 A616_RS31180 fab5a74b944e9b2fe2f595a7482f6d61 329 SUPERFAMILY SSF53807 46 315 3.18E-69 T 29-03-2018 A616_RS31180 fab5a74b944e9b2fe2f595a7482f6d61 329 Pfam PF01497 Periplasmic binding protein 66 304 7.6E-38 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 Gene3D G3DSA:1.10.287.70 118 161 1.9E-14 T 29-03-2018 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 Pfam PF00520 Ion transport protein 7 203 3.6E-18 T 29-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 SUPERFAMILY SSF81324 8 201 1.7E-39 T 29-03-2018 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 Gene3D G3DSA:1.20.120.350 4 117 4.9E-8 T 29-03-2018 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 Gene3D G3DSA:1.20.5.110 163 199 7.6E-11 T 29-03-2018 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 PRINTS PR00169 Potassium channel signature 85 111 4.8E-12 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 PRINTS PR00169 Potassium channel signature 142 164 4.8E-12 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 PRINTS PR00169 Potassium channel signature 36 56 4.8E-12 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 A616_RS23525 4897c2e26366d261f839f3e7de7ddac6 255 PRINTS PR00169 Potassium channel signature 171 197 4.8E-12 T 29-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 A616_RS06835 7912871d00335b4523732a995024c1c5 178 SUPERFAMILY SSF50475 4 166 3.14E-47 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS06835 7912871d00335b4523732a995024c1c5 178 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 162 6.3E-28 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A616_RS06835 7912871d00335b4523732a995024c1c5 178 Gene3D G3DSA:2.30.110.10 5 171 4.7E-36 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 Pfam PF14278 Transcriptional regulator C-terminal region 85 157 2.5E-17 T 29-03-2018 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 Gene3D G3DSA:1.10.10.60 47 159 1.1E-10 T 29-03-2018 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 SUPERFAMILY SSF46689 2 67 7.18E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 7.7E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS23630 7930d7bac34958d0f142813660263cd4 185 Gene3D G3DSA:1.10.10.60 6 46 1.3E-17 T 29-03-2018 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 Pfam PF01497 Periplasmic binding protein 336 521 1.6E-20 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 219 261 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 SMART SM00342 182 265 5.2E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 Gene3D G3DSA:3.40.50.1980 383 544 1.3E-24 T 29-03-2018 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 Gene3D G3DSA:3.40.50.1980 277 382 1.8E-14 T 29-03-2018 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 SUPERFAMILY SSF46689 218 266 1.21E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 SUPERFAMILY SSF53807 273 540 3.92E-38 T 29-03-2018 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 Pfam PF12833 Helix-turn-helix domain 188 266 6.9E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 Gene3D G3DSA:1.10.10.60 227 276 8.0E-16 T 29-03-2018 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 SUPERFAMILY SSF46689 168 216 4.66E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24670 75a68174e41b99dd291c0370390f9c13 548 Gene3D G3DSA:2.60.120.10 14 226 4.2E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS18370 837ad8154822204d168a025ac1b21366 233 Gene3D G3DSA:1.10.150.240 16 90 9.8E-21 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A616_RS18370 837ad8154822204d168a025ac1b21366 233 SUPERFAMILY SSF56784 3 227 1.87E-44 T 29-03-2018 IPR023214 HAD-like domain A616_RS18370 837ad8154822204d168a025ac1b21366 233 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 4.3E-68 T 29-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 A616_RS18370 837ad8154822204d168a025ac1b21366 233 Gene3D G3DSA:3.40.50.1000 91 232 4.8E-28 T 29-03-2018 IPR023214 HAD-like domain A616_RS18370 837ad8154822204d168a025ac1b21366 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 2.6E-23 T 29-03-2018 IPR023214 HAD-like domain A616_RS18370 837ad8154822204d168a025ac1b21366 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 92 190 7.8E-14 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 Gene3D G3DSA:4.10.520.10 1 90 1.7E-36 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 SMART SM00411 1 90 8.8E-48 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 SUPERFAMILY SSF47729 1 90 1.77E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.6E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.6E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.6E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.3E-35 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS25195 ec7546a3d923b65733a5011fd3d13e5a 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Gene3D G3DSA:3.30.110.30 413 487 9.1E-21 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 SUPERFAMILY SSF52954 282 406 6.87E-36 T 29-03-2018 IPR004154 Anticodon-binding A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Gene3D G3DSA:3.30.930.10 1 299 1.6E-69 T 29-03-2018 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 13 488 3.6E-179 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 149 160 6.4E-12 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 110 121 6.4E-12 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 140 148 6.4E-12 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 PRINTS PR01046 Prolyl-tRNA synthetase signature 69 87 6.4E-12 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Gene3D G3DSA:3.40.50.800 300 412 8.4E-36 T 29-03-2018 IPR004154 Anticodon-binding A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 SMART SM00946 415 488 7.0E-24 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 SUPERFAMILY SSF64586 427 488 1.33E-18 T 29-03-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 107 273 9.9E-21 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Hamap MF_01571 Proline--tRNA ligase [proS]. 11 488 45.022 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Pfam PF03129 Anticodon binding domain 293 386 2.2E-18 T 29-03-2018 IPR004154 Anticodon-binding A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 SUPERFAMILY SSF55681 16 280 7.76E-84 T 29-03-2018 A616_RS05955 dedf96d4244058a97c5393f6d30ecbba 488 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 433 488 7.8E-20 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A616_RS28265 22e527f04137a655a8e53aead1736baa 185 Pfam PF04542 Sigma-70 region 2 22 86 3.0E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28265 22e527f04137a655a8e53aead1736baa 185 Gene3D G3DSA:1.10.1740.10 9 91 5.3E-17 T 29-03-2018 A616_RS28265 22e527f04137a655a8e53aead1736baa 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 178 1.0E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28265 22e527f04137a655a8e53aead1736baa 185 Gene3D G3DSA:1.10.10.10 108 183 9.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28265 22e527f04137a655a8e53aead1736baa 185 SUPERFAMILY SSF88659 126 181 3.92E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28265 22e527f04137a655a8e53aead1736baa 185 SUPERFAMILY SSF88946 16 100 2.16E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28265 22e527f04137a655a8e53aead1736baa 185 Pfam PF08281 Sigma-70, region 4 122 175 5.2E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 Gene3D G3DSA:3.40.50.2300 1 120 5.3E-37 T 29-03-2018 A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 SMART SM00862 149 222 5.2E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 SMART SM00448 3 113 9.6E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 SUPERFAMILY SSF46894 126 223 5.26E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 SUPERFAMILY SSF52172 2 121 1.71E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 222 9.6E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 Gene3D G3DSA:1.10.10.10 121 226 3.9E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28695 e7544d06402db0b71265ab30595d7da4 226 Pfam PF00072 Response regulator receiver domain 5 113 3.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 SUPERFAMILY SSF52922 188 325 2.75E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 SUPERFAMILY SSF52518 2 204 4.76E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 Pfam PF02780 Transketolase, C-terminal domain 194 316 4.1E-39 T 29-03-2018 IPR033248 Transketolase, C-terminal domain A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 2.6E-41 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 SMART SM00861 4 179 1.0E-62 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 Gene3D G3DSA:3.40.50.920 195 325 1.1E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS19020 a73eb6e361aafaa423bee867da1d2427 326 Gene3D G3DSA:3.40.50.970 1 194 7.3E-64 T 29-03-2018 A616_RS29875 758da7c471239afd68364e48924856ee 435 SUPERFAMILY SSF143243 286 432 2.35E-45 T 29-03-2018 A616_RS29875 758da7c471239afd68364e48924856ee 435 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 314 428 1.1E-40 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29875 758da7c471239afd68364e48924856ee 435 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 315 430 5.8E-44 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29875 758da7c471239afd68364e48924856ee 435 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 393 414 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29875 758da7c471239afd68364e48924856ee 435 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 286 433 26.292 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29875 758da7c471239afd68364e48924856ee 435 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 366 421 4.0E-14 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 369 527 5.3E-50 T 29-03-2018 IPR000160 GGDEF domain A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 Gene3D G3DSA:3.30.450.20 172 291 1.2E-17 T 29-03-2018 A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 Gene3D G3DSA:3.30.70.270 363 528 2.9E-57 T 29-03-2018 A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 SUPERFAMILY SSF55073 378 526 7.69E-49 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 Pfam PF02743 Cache domain 46 277 6.7E-27 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 SUPERFAMILY SSF103190 209 275 3.69E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 Gene3D G3DSA:3.30.450.20 60 171 8.9E-12 T 29-03-2018 A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 373 523 5.3E-46 T 29-03-2018 IPR000160 GGDEF domain A616_RS28720 b0ae880d266ef240f965a8867ab18c82 530 SMART SM00267 362 527 4.4E-66 T 29-03-2018 IPR000160 GGDEF domain A616_RS11060 766408d11ffb84012ba8efdfe240ee21 438 Gene3D G3DSA:3.60.21.10 86 392 8.4E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS11060 766408d11ffb84012ba8efdfe240ee21 438 SMART SM00854 89 346 3.4E-79 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS11060 766408d11ffb84012ba8efdfe240ee21 438 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 89 344 2.7E-67 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS11060 766408d11ffb84012ba8efdfe240ee21 438 SUPERFAMILY SSF56300 89 377 4.3E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 Pfam PF00501 AMP-binding enzyme 54 461 3.1E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 Gene3D G3DSA:3.40.50.980 40 215 8.1E-42 T 29-03-2018 A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 Gene3D G3DSA:3.40.50.980 216 367 6.3E-39 T 29-03-2018 A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 Gene3D G3DSA:2.30.38.10 368 454 3.1E-20 T 29-03-2018 A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 548 7.8E-25 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 Gene3D G3DSA:3.30.300.30 457 569 2.0E-28 T 29-03-2018 A616_RS11955 c37fa3354f0a054300229b7ffbece0fe 571 SUPERFAMILY SSF56801 18 561 1.83E-163 T 29-03-2018 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 134 2.1E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 SUPERFAMILY SSF47203 245 395 9.34E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 234 1.1E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 Gene3D G3DSA:2.40.110.10 138 238 1.7E-35 T 29-03-2018 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 Gene3D G3DSA:1.20.140.10 239 396 4.8E-50 T 29-03-2018 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 SUPERFAMILY SSF56645 21 259 3.01E-80 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 Gene3D G3DSA:1.10.540.10 9 135 2.7E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 354 373 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS15550 87c62bc1c759780eb0db459fa56a9f28 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 395 1.3E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 Gene3D G3DSA:3.40.50.300 2 227 5.4E-61 T 29-03-2018 A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 SUPERFAMILY SSF52540 148 355 9.66E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 SUPERFAMILY SSF52540 5 211 3.38E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 Pfam PF00271 Helicase conserved C-terminal domain 233 341 3.9E-29 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 Gene3D G3DSA:3.40.50.300 228 461 9.1E-43 T 29-03-2018 A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 Pfam PF00270 DEAD/DEAH box helicase 31 197 2.6E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 SMART SM00487 26 224 1.8E-63 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS30965 c7d44cb95a955125b0ee67608423422f 580 SMART SM00490 260 341 2.2E-30 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 Gene3D G3DSA:1.10.287.990 21 91 1.3E-29 T 29-03-2018 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 197 1.8E-41 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 PIRSF PIRSF000349 1 204 5.3E-84 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 SUPERFAMILY SSF46609 3 92 5.11E-36 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 5.0E-25 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 5.0E-25 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 5.0E-25 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 5.0E-25 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 5.0E-25 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 SUPERFAMILY SSF54719 94 203 3.8E-46 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS17670 4b3cc0714021288205c778bf8dc9d638 204 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 91 9.1E-30 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 SMART SM00382 40 232 4.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 Gene3D G3DSA:3.40.50.300 1 321 1.2E-82 T 29-03-2018 A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 1.9E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 SUPERFAMILY SSF52540 5 254 6.48E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 Pfam PF00005 ABC transporter 32 182 1.1E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15485 851e859a4e1ad8f3b97eea41a463fae4 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 1.3E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 Hamap MF_00300 Chorismate synthase [aroC]. 1 369 35.722 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 PIRSF PIRSF001456 1 383 2.7E-131 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 ProSitePatterns PS00789 Chorismate synthase signature 3. 336 352 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 TIGRFAM TIGR00033 aroC: chorismate synthase 1 366 1.4E-128 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 SUPERFAMILY SSF103263 1 386 7.33E-147 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 Pfam PF01264 Chorismate synthase 1 361 1.0E-123 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS13790 c2fae519da05ff50fb36854de32d7632 387 Gene3D G3DSA:3.60.150.10 1 387 5.1E-141 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 54 120 4.3E-31 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 120 6.0E-15 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 120 3.0E-50 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 Gene3D G3DSA:3.30.1390.10 50 120 2.4E-31 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 SUPERFAMILY SSF48300 1 56 2.09E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 3 49 3.0E-21 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 120 25.071 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 Gene3D G3DSA:1.20.5.710 1 49 2.6E-18 T 29-03-2018 A616_RS01335 b15afbd9b42b25014e62aeed86a177cc 120 SUPERFAMILY SSF54736 50 120 6.28E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A616_RS31700 d10b146b86ac6163c5b56b6cf9b8bce7 239 SMART SM00382 30 234 2.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31700 d10b146b86ac6163c5b56b6cf9b8bce7 239 SUPERFAMILY SSF52540 1 228 7.99E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31700 d10b146b86ac6163c5b56b6cf9b8bce7 239 Pfam PF00005 ABC transporter 21 169 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS31700 d10b146b86ac6163c5b56b6cf9b8bce7 239 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS31700 d10b146b86ac6163c5b56b6cf9b8bce7 239 Gene3D G3DSA:3.40.50.300 1 237 3.9E-65 T 29-03-2018 A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 Pfam PF02195 ParB-like nuclease domain 26 113 1.1E-28 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 SUPERFAMILY SSF110849 25 116 2.38E-29 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 22 198 8.3E-62 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 SMART SM00470 25 114 3.9E-35 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 SUPERFAMILY SSF109709 106 216 1.07E-36 T 29-03-2018 A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 Gene3D G3DSA:1.10.10.730 115 162 2.1E-20 T 29-03-2018 A616_RS32250 95308d5f633f30513ee39f9e7419cf5a 281 Gene3D G3DSA:3.90.1530.10 12 114 3.6E-37 T 29-03-2018 A616_RS00775 2d3027176b3f9a45ab237ea6b37323fb 340 Gene3D G3DSA:3.30.200.20 45 133 2.1E-6 T 29-03-2018 A616_RS00775 2d3027176b3f9a45ab237ea6b37323fb 340 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 58 79 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A616_RS00775 2d3027176b3f9a45ab237ea6b37323fb 340 Gene3D G3DSA:1.10.510.10 134 307 4.9E-18 T 29-03-2018 A616_RS00775 2d3027176b3f9a45ab237ea6b37323fb 340 SMART SM00220 52 299 5.1E-10 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS00775 2d3027176b3f9a45ab237ea6b37323fb 340 Pfam PF00069 Protein kinase domain 52 253 1.6E-19 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS00775 2d3027176b3f9a45ab237ea6b37323fb 340 SUPERFAMILY SSF56112 42 247 1.48E-28 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS27825 8eccdc5d090152dccd5841128542320b 362 Gene3D G3DSA:2.40.50.100 246 292 0.0042 T 29-03-2018 A616_RS27825 8eccdc5d090152dccd5841128542320b 362 SUPERFAMILY SSF52540 4 244 4.17E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27825 8eccdc5d090152dccd5841128542320b 362 Gene3D G3DSA:2.40.50.140 293 343 3.7E-8 T 29-03-2018 A616_RS27825 8eccdc5d090152dccd5841128542320b 362 Gene3D G3DSA:3.40.50.300 1 245 1.9E-70 T 29-03-2018 A616_RS27825 8eccdc5d090152dccd5841128542320b 362 SUPERFAMILY SSF50331 237 358 4.86E-21 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS27825 8eccdc5d090152dccd5841128542320b 362 Pfam PF00005 ABC transporter 20 162 2.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27825 8eccdc5d090152dccd5841128542320b 362 SMART SM00382 29 221 7.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27825 8eccdc5d090152dccd5841128542320b 362 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS27825 8eccdc5d090152dccd5841128542320b 362 Pfam PF08402 TOBE domain 281 350 1.3E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS08970 c8aca68afae3d6f88b01a403e9d5a3a0 145 Pfam PF02082 Transcriptional regulator 2 77 1.8E-20 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS08970 c8aca68afae3d6f88b01a403e9d5a3a0 145 Gene3D G3DSA:1.10.10.10 1 145 5.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08970 c8aca68afae3d6f88b01a403e9d5a3a0 145 SUPERFAMILY SSF46785 5 132 3.32E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14950 cf38ee04ff9faa29182e24c76759ee44 251 Gene3D G3DSA:1.10.3720.10 43 246 6.3E-27 T 29-03-2018 A616_RS14950 cf38ee04ff9faa29182e24c76759ee44 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 241 1.5E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14950 cf38ee04ff9faa29182e24c76759ee44 251 SUPERFAMILY SSF161098 49 232 9.68E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS00645 11a46606b6bc587e374d7476f0c2b607 90 PIRSF PIRSF037257 1 85 5.8E-35 T 29-03-2018 IPR009366 Protein Veg GO:0042710 A616_RS00645 11a46606b6bc587e374d7476f0c2b607 90 Pfam PF06257 Biofilm formation stimulator VEG 5 74 2.4E-30 T 29-03-2018 IPR009366 Protein Veg GO:0042710 A616_RS00645 11a46606b6bc587e374d7476f0c2b607 90 Gene3D G3DSA:2.30.30.100 3 76 4.7E-31 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Pfam PF00158 Sigma-54 interaction domain 368 536 1.5E-71 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Gene3D G3DSA:3.30.450.20 223 356 8.1E-17 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SMART SM00091 236 301 1.3E-6 T 29-03-2018 IPR000014 PAS domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SMART SM00091 117 183 6.2E-7 T 29-03-2018 IPR000014 PAS domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SUPERFAMILY SSF52540 367 613 4.8E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Gene3D G3DSA:1.10.10.60 603 684 1.6E-16 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 647 664 5.8E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 664 684 5.8E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SMART SM00382 388 532 6.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Gene3D G3DSA:3.40.50.300 363 541 1.9E-29 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SUPERFAMILY SSF46689 582 683 5.38E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SUPERFAMILY SSF55785 102 216 5.93E-16 T 29-03-2018 IPR000014 PAS domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SUPERFAMILY SSF55785 217 336 5.06E-13 T 29-03-2018 IPR000014 PAS domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 97 5.7E-7 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 118 227 2.6E-11 T 29-03-2018 IPR000014 PAS domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 236 349 8.1E-16 T 29-03-2018 IPR000014 PAS domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Gene3D G3DSA:3.40.50.720 1 118 1.5E-10 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Gene3D G3DSA:3.30.450.20 120 222 6.0E-18 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 SUPERFAMILY SSF51735 1 91 1.2E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Pfam PF00989 PAS fold 118 218 1.5E-13 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Pfam PF00989 PAS fold 237 339 7.4E-13 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Pfam PF02954 Bacterial regulatory protein, Fis family 641 681 1.0E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 Gene3D G3DSA:1.10.8.60 542 602 5.4E-21 T 29-03-2018 A616_RS13260 18db4e0a5fd6116dce81ae136e592904 689 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS00375 51c0dff3657e083fa9c6b9fe6a4a8b63 165 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 139 1.0E-51 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A616_RS00375 51c0dff3657e083fa9c6b9fe6a4a8b63 165 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 18 137 1.7E-46 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A616_RS00375 51c0dff3657e083fa9c6b9fe6a4a8b63 165 Gene3D G3DSA:2.70.70.10 5 164 1.8E-62 T 29-03-2018 A616_RS00375 51c0dff3657e083fa9c6b9fe6a4a8b63 165 SUPERFAMILY SSF51261 6 161 5.06E-56 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS00375 51c0dff3657e083fa9c6b9fe6a4a8b63 165 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 79 91 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A616_RS02115 a80def32dd7e30cbeb20e6d682ad85d2 244 SUPERFAMILY SSF53187 68 241 1.13E-48 T 29-03-2018 A616_RS02115 a80def32dd7e30cbeb20e6d682ad85d2 244 SMART SM00646 129 238 5.3E-27 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS02115 a80def32dd7e30cbeb20e6d682ad85d2 244 Gene3D G3DSA:3.40.630.40 65 241 6.6E-55 T 29-03-2018 A616_RS02115 a80def32dd7e30cbeb20e6d682ad85d2 244 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 70 238 1.1E-48 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS29780 87a7269fdff265de8ed9aeb6d0dcb8c3 173 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 4.3E-15 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS29780 87a7269fdff265de8ed9aeb6d0dcb8c3 173 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS29780 87a7269fdff265de8ed9aeb6d0dcb8c3 173 PIRSF PIRSF000847 1 170 7.5E-35 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 Gene3D G3DSA:3.60.21.10 142 445 7.2E-81 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 SUPERFAMILY SSF56300 147 426 5.52E-84 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 PRINTS PR01607 Apyrase family signature 488 511 2.9E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 PRINTS PR01607 Apyrase family signature 319 336 2.9E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 PRINTS PR01607 Apyrase family signature 150 168 2.9E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 PRINTS PR01607 Apyrase family signature 562 581 2.9E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 PRINTS PR01607 Apyrase family signature 366 386 2.9E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 PRINTS PR01607 Apyrase family signature 338 361 2.9E-31 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 Gene3D G3DSA:3.90.780.10 446 624 2.9E-62 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 Pfam PF00149 Calcineurin-like phosphoesterase 153 356 8.6E-16 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 SUPERFAMILY SSF55816 425 621 8.11E-62 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10375 0b6f1ea5230cda426e76a40aa6fa1708 624 Pfam PF02872 5'-nucleotidase, C-terminal domain 428 588 3.3E-50 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 SUPERFAMILY SSF55060 162 282 7.91E-31 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 Pfam PF00288 GHMP kinases N terminal domain 86 144 9.1E-13 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 SUPERFAMILY SSF54211 3 157 6.15E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 280 36.183 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 Gene3D G3DSA:3.30.230.10 3 159 6.2E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 286 5.6E-103 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 Pfam PF08544 GHMP kinases C terminal 198 271 1.2E-10 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 PIRSF PIRSF010376 1 290 3.8E-98 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A616_RS00655 bc74168654d0f60384f6bd23eb4dcfe1 292 Gene3D G3DSA:3.30.70.890 161 287 7.1E-30 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain A616_RS19430 bd967b5601288c9aae396665c1164ee1 425 Pfam PF06838 Methionine gamma-lyase 14 414 1.4E-197 T 29-03-2018 IPR009651 Putative methionine gamma-lyase A616_RS19430 bd967b5601288c9aae396665c1164ee1 425 SUPERFAMILY SSF53383 55 398 6.34E-46 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS19430 bd967b5601288c9aae396665c1164ee1 425 Gene3D G3DSA:3.40.640.10 58 271 5.3E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 PIRSF PIRSF007510 1 182 1.1E-78 T 29-03-2018 IPR006340 Protein of unknown function DUF436 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 23 182 1.0E-51 T 29-03-2018 IPR006340 Protein of unknown function DUF436 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 Pfam PF04260 Protein of unknown function (DUF436) 10 179 3.9E-77 T 29-03-2018 IPR006340 Protein of unknown function DUF436 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 8 179 1.7E-75 T 29-03-2018 IPR006340 Protein of unknown function DUF436 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 Hamap MF_00800 UPF0340 protein . 1 189 94.158 T 29-03-2018 IPR006340 Protein of unknown function DUF436 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 SUPERFAMILY SSF110710 5 186 1.15E-75 T 29-03-2018 A616_RS30005 0c79417b0aa0ff81447afe49eec20c30 189 Gene3D G3DSA:3.40.50.10360 5 181 5.4E-80 T 29-03-2018 IPR006340 Protein of unknown function DUF436 A616_RS24300 e79acd09abafa0ef66ea34a11d88ba7a 196 SUPERFAMILY SSF53271 1 182 6.39E-46 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS24300 e79acd09abafa0ef66ea34a11d88ba7a 196 Pfam PF00156 Phosphoribosyl transferase domain 37 157 2.2E-12 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS24300 e79acd09abafa0ef66ea34a11d88ba7a 196 Gene3D G3DSA:3.40.50.2020 3 188 7.9E-29 T 29-03-2018 A616_RS24300 e79acd09abafa0ef66ea34a11d88ba7a 196 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 38.749 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 A616_RS24300 e79acd09abafa0ef66ea34a11d88ba7a 196 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 191 5.6E-76 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 A616_RS29055 5eb08948bbb282307c731c1af18ab67a 341 SUPERFAMILY SSF100950 90 337 4.43E-68 T 29-03-2018 A616_RS29055 5eb08948bbb282307c731c1af18ab67a 341 Gene3D G3DSA:3.40.50.1360 95 341 2.0E-41 T 29-03-2018 A616_RS29055 5eb08948bbb282307c731c1af18ab67a 341 Pfam PF04198 Putative sugar-binding domain 91 338 5.4E-68 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 A616_RS29055 5eb08948bbb282307c731c1af18ab67a 341 SUPERFAMILY SSF46785 20 84 3.03E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29055 5eb08948bbb282307c731c1af18ab67a 341 Gene3D G3DSA:1.10.10.10 17 87 4.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 Gene3D G3DSA:3.30.70.1510 5 81 4.4E-27 T 29-03-2018 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 Gene3D G3DSA:3.30.2300.10 83 163 5.1E-19 T 29-03-2018 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 Gene3D G3DSA:3.40.50.620 175 397 2.1E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 SMART SM00981 74 165 3.9E-21 T 29-03-2018 IPR004114 THUMP domain GO:0003723 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 SUPERFAMILY SSF52402 175 382 1.57E-51 T 29-03-2018 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 SUPERFAMILY SSF143437 3 173 4.45E-53 T 29-03-2018 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 3.1E-70 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 399 161.608 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 374 3.5E-124 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 A616_RS22750 0980fa5e96250be8c21a555ec6c0e17a 399 Pfam PF02926 THUMP domain 42 163 6.0E-22 T 29-03-2018 IPR004114 THUMP domain GO:0003723 A616_RS22240 4838f5faa6d14359eb710d09c9cca285 205 Gene3D G3DSA:1.10.1660.10 6 188 5.1E-12 T 29-03-2018 A616_RS22240 4838f5faa6d14359eb710d09c9cca285 205 Pfam PF13411 MerR HTH family regulatory protein 8 73 1.3E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS22240 4838f5faa6d14359eb710d09c9cca285 205 SUPERFAMILY SSF46955 7 60 2.24E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 SMART SM00387 253 363 1.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 206 2.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 Gene3D G3DSA:1.10.287.130 115 204 1.5E-13 T 29-03-2018 A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 362 1.1E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 SUPERFAMILY SSF55874 197 362 5.37E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 Gene3D G3DSA:3.30.565.10 212 363 2.3E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 SMART SM00388 141 208 2.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 9.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 9.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 9.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03525 70ca1244db25c08df60da0b5a1d689f3 363 SUPERFAMILY SSF47384 127 207 8.83E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS20125 37ac026245b084fb19476ef287a367a8 270 Gene3D G3DSA:3.30.70.270 113 266 1.0E-19 T 29-03-2018 A616_RS20125 37ac026245b084fb19476ef287a367a8 270 Pfam PF00990 Diguanylate cyclase, GGDEF domain 135 222 1.1E-16 T 29-03-2018 IPR000160 GGDEF domain A616_RS20125 37ac026245b084fb19476ef287a367a8 270 SUPERFAMILY SSF54631 1 108 9.88E-22 T 29-03-2018 A616_RS20125 37ac026245b084fb19476ef287a367a8 270 SUPERFAMILY SSF55073 121 260 2.67E-18 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS20125 37ac026245b084fb19476ef287a367a8 270 Pfam PF00571 CBS domain 3 55 5.0E-9 T 29-03-2018 IPR000644 CBS domain A616_RS20125 37ac026245b084fb19476ef287a367a8 270 SMART SM00267 105 270 2.6E-6 T 29-03-2018 IPR000160 GGDEF domain A616_RS20125 37ac026245b084fb19476ef287a367a8 270 SMART SM00116 10 57 5.5E-6 T 29-03-2018 IPR000644 CBS domain A616_RS20125 37ac026245b084fb19476ef287a367a8 270 SMART SM00116 68 115 98.0 T 29-03-2018 IPR000644 CBS domain A616_RS20125 37ac026245b084fb19476ef287a367a8 270 Gene3D G3DSA:3.10.580.10 1 112 2.3E-20 T 29-03-2018 A616_RS20125 37ac026245b084fb19476ef287a367a8 270 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 117 215 1.2E-14 T 29-03-2018 IPR000160 GGDEF domain A616_RS31100 3480a05924cf8f04178112956f10f89f 451 Pfam PF01554 MatE 20 179 1.1E-30 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A616_RS31100 3480a05924cf8f04178112956f10f89f 451 Pfam PF01554 MatE 247 408 3.8E-38 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A616_RS31100 3480a05924cf8f04178112956f10f89f 451 PIRSF PIRSF006603 1 450 2.6E-67 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A616_RS31100 3480a05924cf8f04178112956f10f89f 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 2.2E-100 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 585 645 4.5E-29 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 SUPERFAMILY SSF56719 418 649 7.85E-77 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Gene3D G3DSA:3.30.230.10 236 407 2.8E-55 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 SMART SM00387 37 190 3.9E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 439 453 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 41 56 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 283 296 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 505 521 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 588 604 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 118 132 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 523 540 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 76 89 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR00418 DNA topoisomerase II family signature 543 555 2.8E-65 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Pfam PF00204 DNA gyrase B 237 405 3.1E-56 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Pfam PF01751 Toprim domain 438 549 3.4E-15 T 29-03-2018 IPR006171 TOPRIM domain A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 187 1.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 SUPERFAMILY SSF54211 237 405 2.85E-55 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 257 275 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 327 343 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 12 22 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 195 210 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 375 389 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 609 621 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 625 641 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 389 409 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 PRINTS PR01159 DNA gyrase subunit B signature 210 223 5.5E-44 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 SUPERFAMILY SSF55874 12 228 4.32E-59 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 ProSitePatterns PS00177 DNA topoisomerase II signature. 441 449 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Gene3D G3DSA:3.30.565.10 25 235 9.3E-65 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 Gene3D G3DSA:3.40.50.670 418 652 1.7E-86 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS18860 e9e6307d03af77c0ad71545c709e471f 656 SMART SM00433 41 649 1.5E-296 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS23485 57d45358a9dd45d384a14900d645294c 238 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 212 4.0E-48 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A616_RS23485 57d45358a9dd45d384a14900d645294c 238 Gene3D G3DSA:3.40.50.620 2 238 2.0E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS23485 57d45358a9dd45d384a14900d645294c 238 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 28 235 3.1E-88 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS23485 57d45358a9dd45d384a14900d645294c 238 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 46 234 2.9E-73 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS23485 57d45358a9dd45d384a14900d645294c 238 PIRSF PIRSF000857 2 238 3.4E-90 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS23485 57d45358a9dd45d384a14900d645294c 238 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 3 236 41.275 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS23485 57d45358a9dd45d384a14900d645294c 238 SUPERFAMILY SSF52402 17 199 3.54E-50 T 29-03-2018 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 Gene3D G3DSA:3.40.50.280 572 722 1.9E-40 T 29-03-2018 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 Gene3D G3DSA:3.20.20.240 35 551 6.0E-250 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 Pfam PF02310 B12 binding domain 591 701 3.0E-17 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 588 715 1.0E-61 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 35 555 3.6E-276 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 Pfam PF01642 Methylmalonyl-CoA mutase 36 549 1.5E-240 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 SUPERFAMILY SSF51703 9 551 7.85E-225 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14845 3ef1be5ada624c912bf8dd1516cb4cd5 723 SUPERFAMILY SSF52242 555 716 9.68E-60 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 SUPERFAMILY SSF55136 128 289 4.97E-27 T 29-03-2018 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 SUPERFAMILY SSF46689 57 105 4.44E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 1.3E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 1.3E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 Gene3D G3DSA:3.20.80.10 123 287 4.7E-36 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 SUPERFAMILY SSF46689 6 55 2.55E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 Pfam PF12833 Helix-turn-helix domain 27 104 9.5E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 SMART SM00342 21 104 4.0E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 Pfam PF06445 GyrI-like small molecule binding domain 128 286 1.1E-24 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 Gene3D G3DSA:1.10.10.60 62 122 3.0E-10 T 29-03-2018 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 Gene3D G3DSA:1.10.10.60 4 61 1.3E-10 T 29-03-2018 A616_RS20650 42fb8788be97dde3e1325f862e7b9299 289 SMART SM00871 128 287 6.4E-31 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 325 3.0E-113 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 SUPERFAMILY SSF52374 2 325 2.91E-94 T 29-03-2018 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 1.7E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 1.7E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 1.7E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 1.7E-27 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 Gene3D G3DSA:1.10.240.10 188 308 3.0E-33 T 29-03-2018 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 Pfam PF00579 tRNA synthetases class I (W and Y) 3 281 4.3E-77 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 326 41.34 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 Gene3D G3DSA:3.40.50.620 1 187 1.5E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS07615 34bd9cccf28d70fea27975d41bf1e4e6 328 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 ProSitePatterns PS00770 Aminotransferases class-IV signature. 232 261 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 Pfam PF01063 Amino-transferase class IV 68 309 4.6E-37 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 Gene3D G3DSA:3.20.10.10 175 338 2.3E-52 T 29-03-2018 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 SUPERFAMILY SSF56752 7 352 7.46E-120 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 Gene3D G3DSA:3.30.470.10 1 174 7.7E-72 T 29-03-2018 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 PIRSF PIRSF006468 1 357 6.6E-135 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A616_RS09290 ddd6ce67347781c5b7409fcd3780110d 357 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 43 355 1.4E-127 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 SUPERFAMILY SSF52540 13 471 2.26E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Gene3D G3DSA:1.10.8.10 121 231 1.2E-28 T 29-03-2018 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Gene3D G3DSA:1.10.8.60 365 461 1.9E-30 T 29-03-2018 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 SMART SM01086 365 464 1.4E-22 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 366 436 2.0E-6 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 64 113 1.0E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Gene3D G3DSA:3.40.50.300 58 104 5.6E-4 T 29-03-2018 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 15 473 1.5E-205 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Gene3D G3DSA:1.10.8.10 232 273 9.7E-17 T 29-03-2018 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Pfam PF07724 AAA domain (Cdc48 subfamily) 223 359 6.9E-41 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 12 473 43.472 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A616_RS20065 807bcafc87530e63e4bbb92ba2f0126a 473 SMART SM00382 60 362 6.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 SMART SM00529 25 124 6.4E-39 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 61 1.1E-24 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 Gene3D G3DSA:1.10.10.10 2 73 8.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 SUPERFAMILY SSF47979 64 133 1.26E-18 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 126 2.5E-18 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 Gene3D G3DSA:1.10.60.10 76 136 4.2E-20 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 SUPERFAMILY SSF46785 4 63 1.77E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12970 73344f1834f00e1fc763a42d8166aea1 143 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 2 140 41.53 T 29-03-2018 IPR022897 Transcription regulator MntR A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 SUPERFAMILY SSF64182 57 452 3.53E-122 T 29-03-2018 A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 562 1.3E-178 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 770 3.7E-45 T 29-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 Gene3D G3DSA:3.90.1640.10 64 237 2.2E-29 T 29-03-2018 A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 Gene3D G3DSA:3.40.50.10260 280 483 7.4E-5 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 Pfam PF01368 DHH family 83 226 2.5E-10 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS10725 c3694ad473e026d2ff1b1ddb87b579be 782 Pfam PF02272 DHHA1 domain 314 439 7.5E-18 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 35 389 6.8E-156 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 Gene3D G3DSA:3.10.580.10 275 402 7.4E-14 T 29-03-2018 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 SUPERFAMILY SSF54631 274 391 9.6E-16 T 29-03-2018 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 SUPERFAMILY SSF52540 42 268 1.65E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 Pfam PF00005 ABC transporter 44 191 4.0E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 Pfam PF00571 CBS domain 284 321 1.9E-4 T 29-03-2018 IPR000644 CBS domain A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 Gene3D G3DSA:3.40.50.300 1 274 3.4E-75 T 29-03-2018 A616_RS27925 9c68bfe52eda767bca4128b8373480d6 408 SMART SM00382 52 249 1.8E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 Gene3D G3DSA:3.30.1490.20 124 209 7.4E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 SMART SM00878 336 442 2.9E-70 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 SUPERFAMILY SSF56059 83 349 7.42E-73 T 29-03-2018 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.4E-46 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 4.9E-84 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 Gene3D G3DSA:3.40.50.20 1 123 5.9E-53 T 29-03-2018 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 SUPERFAMILY SSF51246 331 444 2.41E-48 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 1.0E-233 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 SUPERFAMILY SSF52440 1 113 3.02E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.5E-44 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS14865 ed472c7d94def789a38abb4f4a447c69 448 Gene3D G3DSA:3.30.470.20 210 445 5.6E-109 T 29-03-2018 A616_RS03940 db8281460102dce8c7a45268e1f5f467 328 Gene3D G3DSA:3.40.50.2300 36 155 4.8E-17 T 29-03-2018 A616_RS03940 db8281460102dce8c7a45268e1f5f467 328 Gene3D G3DSA:3.40.50.2300 156 292 9.1E-28 T 29-03-2018 A616_RS03940 db8281460102dce8c7a45268e1f5f467 328 Pfam PF13407 Periplasmic binding protein domain 46 296 8.8E-47 T 29-03-2018 IPR025997 Periplasmic binding protein A616_RS03940 db8281460102dce8c7a45268e1f5f467 328 SUPERFAMILY SSF53822 37 314 1.12E-55 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS21815 02447ba3d35a9500a3d1ead5dc9e6480 331 Gene3D G3DSA:3.40.50.1980 54 165 6.9E-33 T 29-03-2018 A616_RS21815 02447ba3d35a9500a3d1ead5dc9e6480 331 Gene3D G3DSA:3.40.50.1980 166 331 1.5E-37 T 29-03-2018 A616_RS21815 02447ba3d35a9500a3d1ead5dc9e6480 331 SUPERFAMILY SSF53807 54 327 6.67E-67 T 29-03-2018 A616_RS21815 02447ba3d35a9500a3d1ead5dc9e6480 331 Pfam PF01497 Periplasmic binding protein 76 304 2.9E-34 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Pfam PF00571 CBS domain 254 306 1.1E-6 T 29-03-2018 IPR000644 CBS domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Pfam PF00571 CBS domain 222 245 6.2E-5 T 29-03-2018 IPR000644 CBS domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Pfam PF07085 DRTGG domain 76 178 6.9E-29 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 SMART SM00116 200 248 3.0 T 29-03-2018 IPR000644 CBS domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 SMART SM00116 259 307 3.0E-6 T 29-03-2018 IPR000644 CBS domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 SUPERFAMILY SSF54637 334 434 1.56E-15 T 29-03-2018 IPR029069 HotDog domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Gene3D G3DSA:3.40.1390.20 70 190 2.6E-26 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 SUPERFAMILY SSF54631 182 307 2.4E-26 T 29-03-2018 A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 59 9.8E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Gene3D G3DSA:3.10.580.10 191 301 3.5E-22 T 29-03-2018 A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 SUPERFAMILY SSF46785 6 60 1.48E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Pfam PF03061 Thioesterase superfamily 367 424 3.1E-4 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 SUPERFAMILY SSF75138 72 185 1.44E-28 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Gene3D G3DSA:1.10.10.10 3 69 6.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07895 80c0167953f3be8084ab73a882bee1be 436 Gene3D G3DSA:3.10.129.10 302 436 1.4E-20 T 29-03-2018 A616_RS12005 7e3538f2d8cc9e431b0faeed4158f1d0 264 Gene3D G3DSA:3.40.1190.20 2 264 2.7E-63 T 29-03-2018 IPR029056 Ribokinase-like A616_RS12005 7e3538f2d8cc9e431b0faeed4158f1d0 264 Pfam PF08543 Phosphomethylpyrimidine kinase 14 258 1.1E-98 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A616_RS12005 7e3538f2d8cc9e431b0faeed4158f1d0 264 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 260 3.7E-106 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS12005 7e3538f2d8cc9e431b0faeed4158f1d0 264 SUPERFAMILY SSF53613 4 261 2.03E-82 T 29-03-2018 IPR029056 Ribokinase-like A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 Pfam PF00231 ATP synthase 5 285 1.0E-101 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 285 4.3E-110 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 Gene3D G3DSA:1.10.287.80 4 42 1.5E-14 T 29-03-2018 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 Gene3D G3DSA:1.10.287.80 240 281 1.4E-12 T 29-03-2018 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 Gene3D G3DSA:3.40.1380.10 43 239 2.6E-80 T 29-03-2018 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 2.3E-39 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 2.3E-39 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 2.3E-39 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.3E-39 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 286 35.815 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 SUPERFAMILY SSF52943 5 285 9.68E-92 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29905 4bcebe6c0a0e3cc1be31e136f47f845a 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SMART SM00052 384 629 2.6E-128 T 29-03-2018 IPR001633 EAL domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SMART SM00086 160 202 3.8E-6 T 29-03-2018 IPR001610 PAC motif A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SUPERFAMILY SSF55073 218 375 1.02E-49 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 Pfam PF08448 PAS fold 93 204 1.6E-13 T 29-03-2018 IPR013656 PAS fold-4 A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SMART SM00091 87 153 8.9E-9 T 29-03-2018 IPR000014 PAS domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SUPERFAMILY SSF55785 92 205 4.04E-20 T 29-03-2018 IPR000014 PAS domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SUPERFAMILY SSF141868 389 636 3.66E-97 T 29-03-2018 IPR001633 EAL domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 Gene3D G3DSA:3.30.70.270 208 375 3.2E-60 T 29-03-2018 A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 Gene3D G3DSA:3.30.450.20 73 207 3.3E-28 T 29-03-2018 A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 PIRSF PIRSF005925 81 207 0.0042 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 PIRSF PIRSF005925 200 645 2.0E-151 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 SMART SM00267 202 374 2.3E-66 T 29-03-2018 IPR000160 GGDEF domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 Pfam PF00990 Diguanylate cyclase, GGDEF domain 213 370 8.2E-52 T 29-03-2018 IPR000160 GGDEF domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 Gene3D G3DSA:3.20.20.450 376 642 2.9E-108 T 29-03-2018 IPR001633 EAL domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 Pfam PF00563 EAL domain 390 624 6.7E-78 T 29-03-2018 IPR001633 EAL domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 210 372 1.2E-42 T 29-03-2018 IPR000160 GGDEF domain A616_RS02265 d4d2d7aba36a437dd5d17e57cfcb97a4 647 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 85 208 7.8E-19 T 29-03-2018 IPR000014 PAS domain A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 3.4E-139 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 Pfam PF04204 Homoserine O-succinyltransferase 2 299 6.5E-144 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 SUPERFAMILY SSF52317 17 297 8.36E-107 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 Gene3D G3DSA:3.40.50.880 34 301 2.8E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-106 T 29-03-2018 A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 56.452 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A616_RS04915 caf196ece8d1ea719c415b65ac335348 306 PIRSF PIRSF000450 1 306 3.2E-154 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A616_RS15795 e1d38a4b3686c831eff48b1f6dd44c96 228 Gene3D G3DSA:2.40.33.20 1 228 3.6E-53 T 29-03-2018 A616_RS15795 e1d38a4b3686c831eff48b1f6dd44c96 228 SUPERFAMILY SSF50800 3 215 7.85E-74 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain A616_RS15795 e1d38a4b3686c831eff48b1f6dd44c96 228 Pfam PF03475 3-alpha domain 171 212 2.0E-15 T 29-03-2018 IPR005163 3-alpha domain A616_RS15795 e1d38a4b3686c831eff48b1f6dd44c96 228 Pfam PF03473 MOSC domain 51 160 3.1E-23 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 Gene3D G3DSA:3.40.640.10 139 351 6.3E-15 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 Gene3D G3DSA:3.90.1150.10 352 461 1.3E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 SMART SM00345 19 78 2.6E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 Gene3D G3DSA:1.10.10.10 2 80 4.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 SUPERFAMILY SSF46785 9 82 6.35E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 3.9E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS02550 44d6cc0ff628f6a606042445f99a6de0 461 SUPERFAMILY SSF53383 102 459 6.29E-52 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS29010 be330711190f46f6c9499ff81474d2c2 335 Pfam PF01032 FecCD transport family 22 331 6.1E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS29010 be330711190f46f6c9499ff81474d2c2 335 Gene3D G3DSA:1.10.3470.10 6 335 2.9E-59 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS29010 be330711190f46f6c9499ff81474d2c2 335 SUPERFAMILY SSF81345 7 331 2.48E-74 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS11375 36e27238324abe794189cfc71c9a3dec 337 SUPERFAMILY SSF53335 61 288 8.59E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS11375 36e27238324abe794189cfc71c9a3dec 337 Gene3D G3DSA:3.40.50.150 46 288 1.9E-16 T 29-03-2018 A616_RS11375 36e27238324abe794189cfc71c9a3dec 337 Pfam PF13649 Methyltransferase domain 92 191 1.2E-9 T 29-03-2018 A616_RS11375 36e27238324abe794189cfc71c9a3dec 337 Pfam PF00301 Rubredoxin 4 44 2.9E-7 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 A616_RS11375 36e27238324abe794189cfc71c9a3dec 337 Gene3D G3DSA:2.20.28.10 1 45 2.4E-9 T 29-03-2018 A616_RS11375 36e27238324abe794189cfc71c9a3dec 337 SUPERFAMILY SSF57802 1 46 3.44E-8 T 29-03-2018 A616_RS19865 87b2e138d2882dd402e2e7dbb112b02a 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.414 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A616_RS19865 87b2e138d2882dd402e2e7dbb112b02a 240 SUPERFAMILY SSF53633 5 238 1.7E-74 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS19865 87b2e138d2882dd402e2e7dbb112b02a 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 238 4.2E-102 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A616_RS19865 87b2e138d2882dd402e2e7dbb112b02a 240 PIRSF PIRSF005650 1 240 2.8E-98 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A616_RS19865 87b2e138d2882dd402e2e7dbb112b02a 240 Pfam PF00696 Amino acid kinase family 7 217 2.7E-30 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS19865 87b2e138d2882dd402e2e7dbb112b02a 240 Gene3D G3DSA:3.40.1160.10 1 239 3.4E-46 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 Gene3D G3DSA:3.40.50.300 1 173 5.8E-29 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 PRINTS PR01100 Shikimate kinase family signature 56 64 3.8E-20 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 PRINTS PR01100 Shikimate kinase family signature 28 41 3.8E-20 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 PRINTS PR01100 Shikimate kinase family signature 4 19 3.8E-20 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 PRINTS PR01100 Shikimate kinase family signature 95 112 3.8E-20 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 PRINTS PR01100 Shikimate kinase family signature 74 83 3.8E-20 T 29-03-2018 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 Pfam PF01202 Shikimate kinase 10 163 1.9E-39 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 Hamap MF_00109 Shikimate kinase [aroK]. 1 165 25.086 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A616_RS12895 7257885004e75ee2c1870bd62280e8b2 173 SUPERFAMILY SSF52540 1 162 1.49E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 243 1.3E-82 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 SMART SM00967 5 80 9.7E-22 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 2.6E-23 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 Gene3D G3DSA:3.40.1280.10 80 247 4.0E-47 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 Gene3D G3DSA:3.30.1330.30 1 75 9.5E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 Pfam PF00588 SpoU rRNA Methylase family 97 237 8.9E-39 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 SUPERFAMILY SSF55315 3 77 9.71E-21 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS01290 029e1ab258fa9e13a381f38b22c3240c 251 SUPERFAMILY SSF75217 68 244 6.54E-49 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 PRINTS PR01415 Ankyrin repeat signature 220 234 1.8E-7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 PRINTS PR01415 Ankyrin repeat signature 166 181 1.8E-7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 Gene3D G3DSA:1.25.40.20 176 263 3.0E-24 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 Pfam PF12796 Ankyrin repeats (3 copies) 71 130 7.1E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 Pfam PF12796 Ankyrin repeats (3 copies) 139 235 8.1E-14 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 SMART SM00248 199 233 0.023 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 SMART SM00248 237 263 660.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 SMART SM00248 99 128 4.5E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 SMART SM00248 132 161 14.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 SMART SM00248 165 195 41.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 SUPERFAMILY SSF48403 71 260 1.66E-50 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04970 77ab321024fa5f9f23a26aaec1f5aa0e 263 Gene3D G3DSA:1.25.40.20 27 175 4.1E-33 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS01285 6f500fa9461f8feaf3ee914d22c5df7e 134 Gene3D G3DSA:1.10.1520.10 4 133 3.6E-20 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS01285 6f500fa9461f8feaf3ee914d22c5df7e 134 Pfam PF00636 Ribonuclease III domain 17 113 1.2E-15 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS01285 6f500fa9461f8feaf3ee914d22c5df7e 134 SMART SM00535 1 134 4.3E-4 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS01285 6f500fa9461f8feaf3ee914d22c5df7e 134 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 131 29.145 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family A616_RS01285 6f500fa9461f8feaf3ee914d22c5df7e 134 SUPERFAMILY SSF69065 9 130 2.96E-39 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A616_RS01285 6f500fa9461f8feaf3ee914d22c5df7e 134 PIRSF PIRSF005520 1 134 5.9E-47 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 664 835 6.1E-13 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 SUPERFAMILY SSF103190 455 544 1.73E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 SUPERFAMILY SSF55073 659 842 8.95E-35 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 Gene3D G3DSA:2.120.10.30 8 172 5.4E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 Gene3D G3DSA:2.120.10.30 173 353 3.3E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 Gene3D G3DSA:3.30.450.20 412 545 2.6E-4 T 29-03-2018 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 SUPERFAMILY SSF63829 29 134 1.14E-8 T 29-03-2018 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 SUPERFAMILY SSF63829 243 341 1.14E-8 T 29-03-2018 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 SUPERFAMILY SSF158472 578 626 4.71E-7 T 29-03-2018 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 SMART SM00304 575 627 1.9E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 Gene3D G3DSA:3.30.70.1230 659 851 1.3E-27 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 A616_RS23280 0d324e25cc918c43ac818abac95b4dcf 918 Gene3D G3DSA:1.25.40.10 852 908 0.027 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 Gene3D G3DSA:3.40.50.720 11 67 0.002 T 29-03-2018 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 1.2E-65 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 SUPERFAMILY SSF48179 183 330 7.14E-70 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 45.136 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 Gene3D G3DSA:1.10.1040.10 68 330 1.5E-118 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 1.1E-76 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 PIRSF PIRSF000116 2 206 3.3E-46 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 PIRSF PIRSF000116 202 332 1.4E-13 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 SUPERFAMILY SSF51735 3 182 1.88E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09485 d16874ff2f2afba0453d82ec2bcd8257 340 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 2.5E-140 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A616_RS11230 ba1c7e00ee830582ed454b3762c5e7f6 196 SMART SM00471 18 145 5.9E-9 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS11230 ba1c7e00ee830582ed454b3762c5e7f6 196 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 14 184 5.3E-51 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 A616_RS11230 ba1c7e00ee830582ed454b3762c5e7f6 196 Pfam PF01966 HD domain 22 134 1.2E-15 T 29-03-2018 IPR006674 HD domain A616_RS11230 ba1c7e00ee830582ed454b3762c5e7f6 196 Gene3D G3DSA:1.10.3210.10 4 191 6.9E-27 T 29-03-2018 A616_RS11230 ba1c7e00ee830582ed454b3762c5e7f6 196 SUPERFAMILY SSF109604 7 180 2.9E-34 T 29-03-2018 A616_RS22300 1cddee0eca33542f551a118879cda0b5 265 SUPERFAMILY SSF64167 1 255 3.4E-63 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A616_RS22300 1cddee0eca33542f551a118879cda0b5 265 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 2 243 2.6E-48 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A616_RS22300 1cddee0eca33542f551a118879cda0b5 265 Pfam PF01975 Survival protein SurE 3 197 2.2E-52 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A616_RS22300 1cddee0eca33542f551a118879cda0b5 265 Gene3D G3DSA:3.40.1210.10 1 265 4.1E-73 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A616_RS22300 1cddee0eca33542f551a118879cda0b5 265 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 260 29.236 T 29-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A616_RS19615 bb9ad1cf08a6370fc144dae64523a510 213 Pfam PF02631 RecX family 86 205 1.8E-29 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 A616_RS19615 bb9ad1cf08a6370fc144dae64523a510 213 Hamap MF_01114 Regulatory protein RecX [recX]. 44 211 15.203 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 A616_RS19615 bb9ad1cf08a6370fc144dae64523a510 213 Gene3D G3DSA:1.10.10.10 160 208 3.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19615 bb9ad1cf08a6370fc144dae64523a510 213 Gene3D G3DSA:1.10.10.10 110 154 3.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19615 bb9ad1cf08a6370fc144dae64523a510 213 Gene3D G3DSA:1.10.10.10 45 109 3.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 7.3E-30 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 6.2E-25 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Gene3D G3DSA:3.30.1360.10 1 86 2.6E-20 T 29-03-2018 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Gene3D G3DSA:3.30.1360.10 123 224 3.1E-28 T 29-03-2018 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 312 3.3E-124 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 SUPERFAMILY SSF56553 50 171 8.76E-43 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 SMART SM00662 20 227 7.0E-103 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.84 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 56 151 9.4E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 2.0E-24 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 SUPERFAMILY SSF55257 172 224 1.27E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 SUPERFAMILY SSF55257 3 50 1.27E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 SUPERFAMILY SSF47789 247 313 3.14E-25 T 29-03-2018 A616_RS01535 09831fbcd0d68c653b2e235f93866646 314 Gene3D G3DSA:1.10.150.20 241 314 1.2E-27 T 29-03-2018 A616_RS19115 5ec1858fb961376f48671a6b05228cbc 212 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 100 198 1.5E-9 T 29-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger A616_RS19115 5ec1858fb961376f48671a6b05228cbc 212 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 86 7.7E-27 T 29-03-2018 IPR010841 Elongation factor G-binding protein, N-terminal A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 23 528 1.4E-110 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 Pfam PF01019 Gamma-glutamyltranspeptidase 38 530 2.7E-167 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 236 252 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 435 452 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 114 132 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 411 426 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 132 151 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 356 374 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 380 398 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 45 70 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 265 284 3.2E-43 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03305 eb0c77c70db409e632567d8496cd3d23 536 SUPERFAMILY SSF56235 5 535 8.1E-186 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 Gene3D G3DSA:3.20.20.120 128 428 1.4E-103 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PIRSF PIRSF001400 1 425 1.7E-196 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 Gene3D G3DSA:3.30.390.10 3 126 8.2E-57 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 424 1.7E-133 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.2E-217 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 SUPERFAMILY SSF54826 3 138 8.25E-61 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 SUPERFAMILY SSF51604 138 426 2.83E-130 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PRINTS PR00148 Enolase signature 311 322 3.0E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PRINTS PR00148 Enolase signature 37 51 3.0E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PRINTS PR00148 Enolase signature 161 174 3.0E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PRINTS PR00148 Enolase signature 363 380 3.0E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PRINTS PR00148 Enolase signature 107 123 3.0E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 PRINTS PR00148 Enolase signature 334 348 3.0E-47 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 SMART SM01193 4 134 2.3E-103 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 SMART SM01192 139 425 1.1E-226 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 Hamap MF_00318 Enolase [eno]. 2 411 46.469 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS29025 a4b1fa514b0f9f519aab03a4ac65afe3 428 Pfam PF03952 Enolase, N-terminal domain 4 134 6.8E-64 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS06700 2526a3b22075eb4594a3719e5e75fc0c 303 Gene3D G3DSA:3.90.1200.10 72 281 9.6E-13 T 29-03-2018 A616_RS06700 2526a3b22075eb4594a3719e5e75fc0c 303 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 53 283 1.4E-46 T 29-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 A616_RS06700 2526a3b22075eb4594a3719e5e75fc0c 303 SUPERFAMILY SSF56112 26 284 8.99E-35 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS17040 c470d03966956b2a549524bf6cbbb99a 70 Pfam PF11213 Protein of unknown function (DUF3006) 3 68 3.9E-15 T 29-03-2018 IPR021377 Protein of unknown function DUF3006 A616_RS09835 ef17404babdc281a6e69edfd7180a55f 307 SUPERFAMILY SSF161098 77 258 1.2E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09835 ef17404babdc281a6e69edfd7180a55f 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 299 6.5E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09835 ef17404babdc281a6e69edfd7180a55f 307 Gene3D G3DSA:1.10.3720.10 1 291 1.1E-22 T 29-03-2018 A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 245 6.8E-66 T 29-03-2018 A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 6.7E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 Gene3D G3DSA:3.40.50.720 40 255 1.6E-63 T 29-03-2018 A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 Gene3D G3DSA:3.40.50.720 1 39 1.7E-8 T 29-03-2018 A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 SUPERFAMILY SSF51735 3 245 5.27E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06950 ddb73c37a036c054ee820f6f598e24d6 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14105 03a563d3b33bc861a3932e710d60e7ca 194 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 194 42.13 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A616_RS14105 03a563d3b33bc861a3932e710d60e7ca 194 Pfam PF00694 Aconitase C-terminal domain 1 123 3.2E-35 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14105 03a563d3b33bc861a3932e710d60e7ca 194 SUPERFAMILY SSF52016 1 192 2.16E-61 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A616_RS14105 03a563d3b33bc861a3932e710d60e7ca 194 Gene3D G3DSA:3.20.19.10 1 175 6.5E-48 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A616_RS14105 03a563d3b33bc861a3932e710d60e7ca 194 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 6.6E-87 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 37 78 2.0E-13 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 10 93 26.285 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 Pfam PF01016 Ribosomal L27 protein 11 88 4.0E-34 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 SUPERFAMILY SSF110324 11 91 8.72E-32 T 29-03-2018 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 43 57 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 Gene3D G3DSA:2.40.50.100 29 93 5.3E-28 T 29-03-2018 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 10 89 5.0E-38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 PRINTS PR00063 Ribosomal protein L27 signature 63 87 9.5E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 PRINTS PR00063 Ribosomal protein L27 signature 38 62 9.5E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10565 230314a281a1abba518266b0f1c858bc 97 PRINTS PR00063 Ribosomal protein L27 signature 13 37 9.5E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS25905 56ce3bc9cfc44d764f8cdcc230402123 330 Gene3D G3DSA:1.10.3470.10 3 330 4.1E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS25905 56ce3bc9cfc44d764f8cdcc230402123 330 SUPERFAMILY SSF81345 9 325 2.62E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS25905 56ce3bc9cfc44d764f8cdcc230402123 330 Pfam PF01032 FecCD transport family 17 323 2.6E-92 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 SUPERFAMILY SSF52283 1 134 3.97E-38 T 29-03-2018 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 SUPERFAMILY SSF143548 319 449 4.97E-35 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Gene3D G3DSA:3.30.70.260 449 527 1.6E-18 T 29-03-2018 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Gene3D G3DSA:3.30.1330.90 317 448 3.5E-37 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 527 1.5E-219 T 29-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 1.9E-35 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Gene3D G3DSA:3.40.50.720 113 284 3.4E-59 T 29-03-2018 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 5.1E-65 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Gene3D G3DSA:3.40.50.720 1 112 2.2E-37 T 29-03-2018 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 SUPERFAMILY SSF51735 98 282 1.37E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 SUPERFAMILY SSF55021 451 526 1.86E-18 T 29-03-2018 A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 Pfam PF01842 ACT domain 455 515 4.0E-9 T 29-03-2018 IPR002912 ACT domain A616_RS13540 e4717e90a9e898ba182799d09eb4fe82 527 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 Gene3D G3DSA:3.20.70.20 279 545 5.9E-28 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 Gene3D G3DSA:3.20.70.20 7 168 6.0E-14 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 SUPERFAMILY SSF51998 17 332 9.16E-126 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 SUPERFAMILY SSF51998 369 752 9.16E-126 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 Gene3D G3DSA:3.30.1620.10 169 272 1.4E-15 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 Gene3D G3DSA:3.90.1390.10 576 680 2.8E-20 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 Gene3D G3DSA:3.90.1390.10 681 752 4.0E-8 T 29-03-2018 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 TIGRFAM TIGR02505 RTPR: ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent 26 753 5.5E-111 T 29-03-2018 IPR013345 Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0006260|GO:0008998|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 A616_RS07965 45695fd3e76c74ba7df92d0b878f0b52 753 Pfam PF02867 Ribonucleotide reductase, barrel domain 382 533 2.3E-14 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF47336 24 121 3.27E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF53335 2674 2848 5.87E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:1.10.1200.10 1480 1550 2.1E-20 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:1.10.10.10 1101 1217 9.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.30.300.30 1374 1479 1.5E-19 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF52777 111 283 5.34E-22 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SMART SM00823 Phosphopantetheine attachment site 2940 3009 0.073 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SMART SM00823 Phosphopantetheine attachment site 1474 1543 0.0028 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF56801 1407 1486 4.46E-139 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF56801 557 1019 4.46E-139 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.30.300.30 2429 2536 9.1E-13 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF56801 2873 2953 6.93E-144 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF56801 2014 2487 6.93E-144 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:2.30.38.10 878 955 1.1E-22 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:2.30.38.10 2344 2423 3.7E-20 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF52777 1748 1994 9.89E-44 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF47336 1466 1539 1.83E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.40.50.980 558 714 1.5E-39 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.40.50.980 2021 2179 3.2E-43 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF52777 287 532 5.45E-43 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.30.300.30 2843 2927 9.1E-13 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:1.10.1200.10 19 90 5.5E-10 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2174 2185 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 ProSitePatterns PS00455 Putative AMP-binding domain signature. 708 719 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00550 Phosphopantetheine attachment site 2942 3005 4.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00550 Phosphopantetheine attachment site 28 80 1.5E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00550 Phosphopantetheine attachment site 1476 1539 3.4E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:1.10.1200.10 2928 3018 6.7E-19 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00668 Condensation domain 110 546 9.2E-35 T 29-03-2018 IPR001242 Condensation domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00668 Condensation domain 1566 1988 1.7E-36 T 29-03-2018 IPR001242 Condensation domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:1.10.10.10 2537 2594 0.0078 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF53335 1207 1387 2.57E-20 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF52777 1560 1761 5.34E-28 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.40.50.150 1218 1373 2.8E-14 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 SUPERFAMILY SSF47336 2933 3005 6.02E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.30.559.10 1551 1750 5.6E-28 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.30.559.10 91 295 5.9E-20 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF13193 AMP-binding enzyme C-terminal domain 973 1019 7.1E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1498 1513 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00501 AMP-binding enzyme 569 965 1.6E-88 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF00501 AMP-binding enzyme 2030 2433 3.2E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.40.50.150 2595 2842 3.0E-16 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 590 989 4.9E-120 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2051 2457 3.1E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.30.300.30 958 1100 1.8E-18 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.40.50.980 715 869 2.2E-33 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Gene3D G3DSA:3.40.50.980 2180 2338 2.3E-38 T 29-03-2018 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF08242 Methyltransferase domain 1230 1330 7.5E-12 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS24435 d2a2a035949b3ef6d00fd802b9aff2b0 3024 Pfam PF08242 Methyltransferase domain 2692 2792 5.4E-10 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS18060 1e8502a14fec58e7bc601b973ec2602e 334 SUPERFAMILY SSF56112 24 290 5.71E-44 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS18060 1e8502a14fec58e7bc601b973ec2602e 334 Gene3D G3DSA:3.30.200.20 7 117 7.3E-14 T 29-03-2018 A616_RS18060 1e8502a14fec58e7bc601b973ec2602e 334 Pfam PF01636 Phosphotransferase enzyme family 48 268 1.5E-24 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS18060 1e8502a14fec58e7bc601b973ec2602e 334 Gene3D G3DSA:3.90.1200.10 118 325 9.3E-24 T 29-03-2018 A616_RS26440 bbf9433a89b745a71432fcd50d28db50 209 SUPERFAMILY SSF46785 7 188 4.73E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26440 bbf9433a89b745a71432fcd50d28db50 209 Gene3D G3DSA:1.10.10.10 1 80 1.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26440 bbf9433a89b745a71432fcd50d28db50 209 Pfam PF08220 DeoR-like helix-turn-helix domain 10 52 2.3E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS26440 bbf9433a89b745a71432fcd50d28db50 209 SMART SM00420 9 60 0.006 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Gene3D G3DSA:3.30.1490.100 257 368 1.3E-22 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 SUPERFAMILY SSF100879 253 352 1.1E-14 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Gene3D G3DSA:3.30.70.270 123 181 1.0E-10 T 29-03-2018 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Gene3D G3DSA:3.30.70.270 48 122 7.2E-20 T 29-03-2018 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Pfam PF11799 impB/mucB/samB family C-terminal domain 251 359 3.5E-15 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 SUPERFAMILY SSF56672 8 245 2.22E-68 T 29-03-2018 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Pfam PF00817 impB/mucB/samB family 14 161 1.3E-40 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Gene3D G3DSA:1.10.150.20 182 256 5.5E-21 T 29-03-2018 A616_RS17005 e31e65df334b676456cbeef486461a4c 415 Hamap MF_01113 DNA polymerase IV [dinB]. 7 365 29.966 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 Pfam PF00664 ABC transporter transmembrane region 31 298 1.4E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 SMART SM00382 367 561 1.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 Pfam PF00005 ABC transporter 358 509 1.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 Gene3D G3DSA:1.20.1560.10 3 329 3.4E-65 T 29-03-2018 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 SUPERFAMILY SSF90123 18 332 1.57E-68 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 Gene3D G3DSA:3.40.50.300 330 585 4.9E-79 T 29-03-2018 A616_RS15675 0363577dccd9d5185c7104e82a2e3e92 593 SUPERFAMILY SSF52540 334 580 1.48E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 SUPERFAMILY SSF46689 20 95 5.32E-22 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 Pfam PF01380 SIS domain 142 268 2.8E-20 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 SUPERFAMILY SSF53697 113 291 1.78E-39 T 29-03-2018 A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 ProSitePatterns PS00356 LacI-type HTH domain signature. 55 73 - T 29-03-2018 A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 Gene3D G3DSA:3.40.50.10490 135 292 1.9E-30 T 29-03-2018 A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 Gene3D G3DSA:1.10.10.10 18 134 3.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25115 aa7fc01a2f1803604a75e1cc41e655dd 297 Pfam PF01418 Helix-turn-helix domain, rpiR family 20 94 5.1E-24 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 Pfam PF08239 Bacterial SH3 domain 113 163 1.8E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 Pfam PF01476 LysM domain 28 69 1.6E-13 T 29-03-2018 IPR018392 LysM domain A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 Pfam PF00877 NlpC/P60 family 194 284 1.2E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 Gene3D G3DSA:2.40.50.110 94 165 3.1E-19 T 29-03-2018 A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 SMART SM00287 104 166 3.4E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 Gene3D G3DSA:3.10.350.10 17 93 1.0E-15 T 29-03-2018 A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 SMART SM00257 27 70 3.0E-13 T 29-03-2018 IPR018392 LysM domain A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 SUPERFAMILY SSF54001 183 298 1.28E-36 T 29-03-2018 A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 Gene3D G3DSA:3.90.1720.10 177 302 3.7E-33 T 29-03-2018 A616_RS14330 eba408e4c40ebca4bf61d9f3edd442fa 302 SUPERFAMILY SSF54106 27 70 1.83E-11 T 29-03-2018 IPR018392 LysM domain A616_RS27730 230868cc8a670b7b852c57974079d39f 222 SMART SM00849 18 202 1.4E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS27730 230868cc8a670b7b852c57974079d39f 222 Gene3D G3DSA:3.60.15.10 8 213 5.4E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS27730 230868cc8a670b7b852c57974079d39f 222 Pfam PF00753 Metallo-beta-lactamase superfamily 22 202 3.0E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS27730 230868cc8a670b7b852c57974079d39f 222 SUPERFAMILY SSF56281 1 209 7.34E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 SUPERFAMILY SSF55874 285 450 6.29E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 SMART SM00304 175 228 4.5E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 450 6.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 SUPERFAMILY SSF47384 212 295 4.51E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 295 9.7E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 SMART SM00387 341 452 1.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 Gene3D G3DSA:3.30.565.10 325 453 2.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 SMART SM00388 229 296 1.8E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS15775 2edc5f265d16ee75f5d07be5a49c35f9 454 Gene3D G3DSA:1.10.287.130 219 292 2.0E-17 T 29-03-2018 A616_RS16345 4b5369fb36624d1c63511ddc3481895d 291 SUPERFAMILY SSF53448 9 169 4.31E-11 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS16345 4b5369fb36624d1c63511ddc3481895d 291 Gene3D G3DSA:3.90.550.10 6 246 2.0E-9 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS16345 4b5369fb36624d1c63511ddc3481895d 291 Pfam PF00535 Glycosyl transferase family 2 12 158 4.4E-6 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS15850 693032962322b7faccbb45b0fb86ce64 310 Gene3D G3DSA:1.10.3720.10 3 293 3.7E-36 T 29-03-2018 A616_RS15850 693032962322b7faccbb45b0fb86ce64 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.4E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15850 693032962322b7faccbb45b0fb86ce64 310 SUPERFAMILY SSF161098 90 292 7.63E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS22175 7a08f55357fa5d88a8593a1e9057935c 169 Hamap MF_01444 Putative phosphoesterase . 1 168 37.894 T 29-03-2018 IPR022932 Putative phosphoesterase YjcG A616_RS22175 7a08f55357fa5d88a8593a1e9057935c 169 Pfam PF13563 2'-5' RNA ligase superfamily 9 153 1.8E-23 T 29-03-2018 A616_RS22175 7a08f55357fa5d88a8593a1e9057935c 169 Gene3D G3DSA:3.90.1140.10 1 169 1.7E-26 T 29-03-2018 A616_RS22175 7a08f55357fa5d88a8593a1e9057935c 169 SUPERFAMILY SSF55144 1 167 1.4E-26 T 29-03-2018 IPR009097 Cyclic phosphodiesterase A616_RS23400 84f4a54cec9a4c5fb4f25474aefcab00 409 SUPERFAMILY SSF53756 4 380 1.22E-75 T 29-03-2018 A616_RS23400 84f4a54cec9a4c5fb4f25474aefcab00 409 Gene3D G3DSA:3.40.50.2000 2 186 4.8E-28 T 29-03-2018 A616_RS23400 84f4a54cec9a4c5fb4f25474aefcab00 409 Pfam PF00534 Glycosyl transferases group 1 193 358 3.1E-35 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS23400 84f4a54cec9a4c5fb4f25474aefcab00 409 Gene3D G3DSA:3.40.50.2000 187 361 2.0E-43 T 29-03-2018 A616_RS23400 84f4a54cec9a4c5fb4f25474aefcab00 409 Pfam PF13477 Glycosyl transferase 4-like 17 139 1.2E-21 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 SMART SM00849 22 217 2.8E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 Hamap MF_01491 Ribonuclease J [rnj]. 5 556 45.535 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 SUPERFAMILY SSF56281 11 424 8.25E-95 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 364 411 2.9E-10 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 Gene3D G3DSA:3.60.15.10 3 449 1.7E-60 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 PIRSF PIRSF004803 3 556 5.6E-233 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 554 3.2E-206 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A616_RS02635 c44d4b93f4691702c64da4b0e77a6cf2 556 Pfam PF00753 Metallo-beta-lactamase superfamily 20 168 1.7E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02770 8094b548acc82983a1c530d1770a3e70 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 9.2E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS02770 8094b548acc82983a1c530d1770a3e70 315 SUPERFAMILY SSF161098 71 305 7.33E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS02770 8094b548acc82983a1c530d1770a3e70 315 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 311 6.3E-87 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 A616_RS02770 8094b548acc82983a1c530d1770a3e70 315 Gene3D G3DSA:1.10.3720.10 22 308 5.6E-41 T 29-03-2018 A616_RS26615 8d1220f6c643fd678a26ddfa080e03d7 226 SUPERFAMILY SSF51735 1 206 6.81E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26615 8d1220f6c643fd678a26ddfa080e03d7 226 Gene3D G3DSA:3.40.50.720 1 216 4.2E-23 T 29-03-2018 A616_RS26615 8d1220f6c643fd678a26ddfa080e03d7 226 Pfam PF13460 NAD(P)H-binding 10 122 4.3E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 Gene3D G3DSA:1.25.40.20 235 349 1.8E-23 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 Gene3D G3DSA:1.25.40.20 53 234 9.2E-20 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 SMART SM00248 285 314 0.0027 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 SMART SM00248 183 212 3.6E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 SMART SM00248 252 281 0.0023 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 SMART SM00248 146 175 260.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 SMART SM00248 220 249 0.0016 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 Pfam PF12796 Ankyrin repeats (3 copies) 225 312 9.3E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 Pfam PF12796 Ankyrin repeats (3 copies) 154 212 8.3E-7 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS24860 82e8b9dd2ced4e1f34cdd52739bd326d 351 SUPERFAMILY SSF48403 152 345 4.97E-34 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS02050 cb6bf488c05c9dbd4498971762fd2c07 446 SUPERFAMILY SSF55469 259 441 1.31E-35 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS02050 cb6bf488c05c9dbd4498971762fd2c07 446 SUPERFAMILY SSF53474 14 252 3.17E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS02050 cb6bf488c05c9dbd4498971762fd2c07 446 Pfam PF00756 Putative esterase 16 205 4.9E-30 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A616_RS02050 cb6bf488c05c9dbd4498971762fd2c07 446 Gene3D G3DSA:3.40.109.10 259 444 1.2E-33 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS02050 cb6bf488c05c9dbd4498971762fd2c07 446 Pfam PF00881 Nitroreductase family 265 423 5.6E-23 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS02050 cb6bf488c05c9dbd4498971762fd2c07 446 Gene3D G3DSA:3.40.50.1820 11 258 2.4E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24695 1736921b4e620637e3e467446c6ed095 569 SUPERFAMILY SSF161098 292 547 1.42E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24695 1736921b4e620637e3e467446c6ed095 569 SUPERFAMILY SSF161098 12 278 1.06E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24695 1736921b4e620637e3e467446c6ed095 569 Gene3D G3DSA:1.10.3720.10 299 560 4.9E-32 T 29-03-2018 A616_RS24695 1736921b4e620637e3e467446c6ed095 569 Gene3D G3DSA:1.10.3720.10 14 280 2.3E-40 T 29-03-2018 A616_RS24695 1736921b4e620637e3e467446c6ed095 569 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 15 559 7.6E-224 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative A616_RS24695 1736921b4e620637e3e467446c6ed095 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 277 1.5E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24695 1736921b4e620637e3e467446c6ed095 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 387 556 5.7E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25110 b68c383d117439eb834f870127a01087 254 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 43.748 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A616_RS25110 b68c383d117439eb834f870127a01087 254 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 244 1.1E-96 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A616_RS25110 b68c383d117439eb834f870127a01087 254 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 226 1.3E-22 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 A616_RS25110 b68c383d117439eb834f870127a01087 254 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 29-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 A616_RS25110 b68c383d117439eb834f870127a01087 254 Gene3D G3DSA:3.40.50.1360 1 250 7.1E-80 T 29-03-2018 A616_RS25110 b68c383d117439eb834f870127a01087 254 SUPERFAMILY SSF100950 1 244 1.12E-93 T 29-03-2018 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 SUPERFAMILY SSF51395 10 317 4.03E-90 T 29-03-2018 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 Gene3D G3DSA:1.10.1200.80 252 331 1.4E-15 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 PIRSF PIRSF006621 1 326 1.0E-106 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 Pfam PF01207 Dihydrouridine synthase (Dus) 13 314 5.4E-105 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 9.6E-130 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 Gene3D G3DSA:3.20.20.70 6 247 5.1E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS01165 e6a9f0264a0030d3cebec62fec464a99 342 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 95 113 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 1.7E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 322 1.7E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 299 1.7E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 SUPERFAMILY SSF55874 213 341 6.16E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 SUPERFAMILY SSF55785 9 120 2.27E-16 T 29-03-2018 IPR000014 PAS domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 Gene3D G3DSA:3.30.450.20 5 116 4.0E-18 T 29-03-2018 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 SMART SM00091 9 76 9.9E-4 T 29-03-2018 IPR000014 PAS domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 Pfam PF13426 PAS domain 20 121 3.9E-10 T 29-03-2018 IPR000014 PAS domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 Pfam PF07730 Histidine kinase 146 211 3.5E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 PIRSF PIRSF037432 2 342 4.3E-79 T 29-03-2018 IPR017203 Signal transduction histidine kinase, NreB GO:0000155|GO:0004673|GO:0005506|GO:0005524|GO:0005737|GO:0018106 A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 251 343 5.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 SMART SM00387 249 344 9.2E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 129 1.4E-13 T 29-03-2018 IPR000014 PAS domain A616_RS02365 1bcf5220c461eb94a9529ac1539fe8b6 356 Gene3D G3DSA:3.30.565.10 117 343 4.5E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 Gene3D G3DSA:3.30.360.10 160 300 7.3E-57 T 29-03-2018 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 12 131 4.0E-20 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 Gene3D G3DSA:3.30.70.260 348 427 6.5E-15 T 29-03-2018 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 Pfam PF00742 Homoserine dehydrogenase 139 317 6.0E-67 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 Pfam PF01842 ACT domain 352 410 1.1E-8 T 29-03-2018 IPR002912 ACT domain A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 SUPERFAMILY SSF51735 3 160 1.77E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 SUPERFAMILY SSF55347 139 304 1.5E-52 T 29-03-2018 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 Gene3D G3DSA:3.40.50.720 2 159 6.4E-34 T 29-03-2018 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 SUPERFAMILY SSF55021 350 422 1.25E-11 T 29-03-2018 A616_RS10600 e15314320ba3380cbfbf8bba08d25d74 433 PIRSF PIRSF000098 3 431 3.2E-171 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 5 404 7.5E-169 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 Pfam PF01546 Peptidase family M20/M25/M40 75 403 9.5E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 SUPERFAMILY SSF53187 333 406 1.23E-93 T 29-03-2018 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 SUPERFAMILY SSF53187 2 221 1.23E-93 T 29-03-2018 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 SUPERFAMILY SSF55031 211 325 7.85E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS07660 1dd83c758134688be7f683d54befc35e 407 Gene3D G3DSA:3.40.630.10 1 244 1.7E-51 T 29-03-2018 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 Gene3D G3DSA:3.40.630.10 245 407 3.4E-26 T 29-03-2018 A616_RS07660 1dd83c758134688be7f683d54befc35e 407 Pfam PF07687 Peptidase dimerisation domain 210 310 4.6E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS07660 1dd83c758134688be7f683d54befc35e 407 PIRSF PIRSF001235 1 407 8.7E-146 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A616_RS01925 51fbea7b7f7939c606760dfc1368a573 104 SUPERFAMILY SSF103481 5 101 3.53E-17 T 29-03-2018 A616_RS01925 51fbea7b7f7939c606760dfc1368a573 104 Pfam PF00893 Small Multidrug Resistance protein 1 91 4.9E-29 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS15230 1b489d81e46c6d2e2bcb6b8f303c7d46 436 Gene3D G3DSA:1.10.3720.10 14 425 7.1E-57 T 29-03-2018 A616_RS15230 1b489d81e46c6d2e2bcb6b8f303c7d46 436 SUPERFAMILY SSF161098 191 418 5.89E-62 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15230 1b489d81e46c6d2e2bcb6b8f303c7d46 436 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 222 425 4.4E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 SUPERFAMILY SSF50104 1 101 1.54E-37 T 29-03-2018 IPR008991 Translation protein SH3-like domain A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 1.6E-29 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 Gene3D G3DSA:2.30.30.30 1 100 1.0E-36 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 96 21.865 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 1.9E-40 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 Pfam PF00467 KOW motif 5 36 2.0E-8 T 29-03-2018 IPR005824 KOW A616_RS01455 7fe2ce3e80f8cfe03e7477c67fa354bb 104 SMART SM00739 2 29 2.1E-5 T 29-03-2018 IPR005824 KOW A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 Gene3D G3DSA:3.40.50.300 269 447 1.1E-27 T 29-03-2018 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 361 376 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 488 497 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 Gene3D G3DSA:1.10.8.60 448 518 8.7E-23 T 29-03-2018 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 SUPERFAMILY SSF46689 488 584 4.66E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 Pfam PF02954 Bacterial regulatory protein, Fis family 540 580 7.6E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 Gene3D G3DSA:1.10.10.60 519 584 5.8E-11 T 29-03-2018 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 SUPERFAMILY SSF52540 273 518 1.76E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 SMART SM00382 294 438 5.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 Pfam PF00158 Sigma-54 interaction domain 274 442 3.9E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS31505 c4dba3d0a042c60759c2e4320bddb558 584 Gene3D G3DSA:3.30.450.20 134 213 1.3E-4 T 29-03-2018 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 Gene3D G3DSA:3.30.70.920 52 137 1.4E-13 T 29-03-2018 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 Gene3D G3DSA:1.10.10.10 2 51 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 SUPERFAMILY SSF54909 64 136 8.18E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 SUPERFAMILY SSF46785 1 60 2.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 4.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 SMART SM00344 2 108 6.0E-27 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 5.3E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 5.3E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 5.3E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02465 6e931e099fafaed946c4d97003fcda0b 137 Pfam PF01037 Lrp/AsnC ligand binding domain 77 121 5.3E-9 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 4 460 39.997 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 397 1.4E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 SUPERFAMILY SSF53623 90 311 5.1E-65 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 SUPERFAMILY SSF53244 312 456 1.53E-44 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Pfam PF01225 Mur ligase family, catalytic domain 6 103 4.2E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Pfam PF08245 Mur ligase middle domain 109 293 5.4E-25 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Gene3D G3DSA:3.40.1190.10 93 313 9.8E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 SUPERFAMILY SSF51984 5 92 1.57E-27 T 29-03-2018 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 6 451 1.0E-154 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Gene3D G3DSA:3.90.190.20 314 460 7.4E-37 T 29-03-2018 A616_RS10455 52d97d85266ba1e0084bf4abaa5fa735 460 Gene3D G3DSA:3.40.50.720 1 92 2.9E-16 T 29-03-2018 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.6E-85 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 Gene3D G3DSA:3.40.50.720 140 263 2.5E-42 T 29-03-2018 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 6.0E-42 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.302 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 6.0E-73 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 SUPERFAMILY SSF53223 1 121 1.92E-41 T 29-03-2018 A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 SUPERFAMILY SSF51735 122 279 1.83E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13125 ef15065310c6eb5391d4a854fa342e83 284 Gene3D G3DSA:3.40.50.10860 11 139 1.9E-50 T 29-03-2018 A616_RS27420 cdaf7449d101f79a50f1cdf85e56964d 480 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS27420 cdaf7449d101f79a50f1cdf85e56964d 480 Gene3D G3DSA:3.40.605.10 2 266 8.0E-106 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS27420 cdaf7449d101f79a50f1cdf85e56964d 480 Pfam PF00171 Aldehyde dehydrogenase family 13 476 8.0E-182 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS27420 cdaf7449d101f79a50f1cdf85e56964d 480 SUPERFAMILY SSF53720 4 479 9.16E-178 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS27420 cdaf7449d101f79a50f1cdf85e56964d 480 PIRSF PIRSF036492 23 477 1.9E-85 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A616_RS27420 cdaf7449d101f79a50f1cdf85e56964d 480 Gene3D G3DSA:3.40.309.10 267 462 2.6E-76 T 29-03-2018 A616_RS07565 956afcafa225426a9fc61caaff0e1678 129 Gene3D G3DSA:3.10.180.10 1 123 4.3E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS07565 956afcafa225426a9fc61caaff0e1678 129 SUPERFAMILY SSF54593 6 118 1.2E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS20360 a285a16e6597c302f91ea05d8619ea61 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A616_RS20360 a285a16e6597c302f91ea05d8619ea61 188 Gene3D G3DSA:3.40.50.150 1 184 9.0E-34 T 29-03-2018 A616_RS20360 a285a16e6597c302f91ea05d8619ea61 188 Pfam PF03602 Conserved hypothetical protein 95 1 180 6.2E-59 T 29-03-2018 A616_RS20360 a285a16e6597c302f91ea05d8619ea61 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 180 4.7E-53 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A616_RS20360 a285a16e6597c302f91ea05d8619ea61 188 SUPERFAMILY SSF53335 1 181 4.46E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS20360 a285a16e6597c302f91ea05d8619ea61 188 PIRSF PIRSF004553 1 183 2.8E-53 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A616_RS02410 528cb1f0761bd5ffad3448bd48d86814 454 SUPERFAMILY SSF69318 64 189 1.31E-11 T 29-03-2018 A616_RS02410 528cb1f0761bd5ffad3448bd48d86814 454 Gene3D G3DSA:2.130.10.130 34 197 1.4E-10 T 29-03-2018 A616_RS11160 0bc4ac8382cc09dac730763667d400ab 541 Gene3D G3DSA:3.90.76.10 55 213 3.3E-39 T 29-03-2018 A616_RS11160 0bc4ac8382cc09dac730763667d400ab 541 Gene3D G3DSA:3.10.105.10 312 511 1.3E-50 T 29-03-2018 A616_RS11160 0bc4ac8382cc09dac730763667d400ab 541 PIRSF PIRSF002741 2 540 3.7E-121 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS11160 0bc4ac8382cc09dac730763667d400ab 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 463 4.4E-83 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS11160 0bc4ac8382cc09dac730763667d400ab 541 SUPERFAMILY SSF53850 50 535 2.41E-125 T 29-03-2018 A616_RS11160 0bc4ac8382cc09dac730763667d400ab 541 Gene3D G3DSA:3.40.190.10 214 311 1.1E-21 T 29-03-2018 A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 Gene3D G3DSA:3.20.20.190 439 688 1.1E-65 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 449 682 7.3E-44 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 Gene3D G3DSA:2.60.40.1260 18 169 9.3E-21 T 29-03-2018 IPR001322 Lamin Tail Domain A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 Pfam PF00932 Lamin Tail Domain 30 164 1.3E-17 T 29-03-2018 IPR001322 Lamin Tail Domain A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 SUPERFAMILY SSF51695 286 431 3.4E-9 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 Gene3D G3DSA:3.20.20.190 170 438 2.4E-14 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 SUPERFAMILY SSF74853 27 164 3.14E-10 T 29-03-2018 IPR001322 Lamin Tail Domain A616_RS31375 7c959a464dbadb4cc1865ff2a81f93f5 692 SUPERFAMILY SSF51695 443 686 1.47E-66 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS13170 9ac045995758a6ca5620854dc165c283 574 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 564 2.8E-190 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A616_RS13170 9ac045995758a6ca5620854dc165c283 574 SUPERFAMILY SSF52540 1 219 4.68E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13170 9ac045995758a6ca5620854dc165c283 574 SUPERFAMILY SSF52540 2 50 2.11E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13170 9ac045995758a6ca5620854dc165c283 574 SUPERFAMILY SSF52540 303 520 2.11E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13170 9ac045995758a6ca5620854dc165c283 574 PIRSF PIRSF003128 1 569 1.6E-183 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A616_RS13170 9ac045995758a6ca5620854dc165c283 574 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 521 2.5E-15 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A616_RS13170 9ac045995758a6ca5620854dc165c283 574 Gene3D G3DSA:3.40.50.300 1 237 5.8E-25 T 29-03-2018 A616_RS13170 9ac045995758a6ca5620854dc165c283 574 Gene3D G3DSA:3.40.50.300 238 546 2.1E-21 T 29-03-2018 A616_RS15750 bad2d9cf2f9b870657364c98e417f886 278 Pfam PF04951 D-aminopeptidase 1 263 3.5E-99 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A616_RS15750 bad2d9cf2f9b870657364c98e417f886 278 SUPERFAMILY SSF63992 1 268 7.45E-88 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A616_RS15750 bad2d9cf2f9b870657364c98e417f886 278 Gene3D G3DSA:3.40.50.10780 1 211 3.5E-83 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal A616_RS15750 bad2d9cf2f9b870657364c98e417f886 278 PIRSF PIRSF015853 1 275 1.7E-94 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A616_RS15750 bad2d9cf2f9b870657364c98e417f886 278 Gene3D G3DSA:3.30.1360.130 212 270 3.4E-11 T 29-03-2018 A616_RS08210 bd9fcc1eba6e7ec2358b84d464743a60 159 Pfam PF14085 Domain of unknown function (DUF4265) 22 129 1.2E-19 T 29-03-2018 IPR025361 Protein of unknown function DUF4265 A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 Gene3D G3DSA:1.20.1250.20 13 222 1.1E-25 T 29-03-2018 A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 Pfam PF00083 Sugar (and other) transporter 21 240 2.1E-27 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 SUPERFAMILY SSF103473 11 425 1.28E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 Pfam PF07690 Major Facilitator Superfamily 269 429 3.0E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 Gene3D G3DSA:1.20.1250.20 223 436 3.4E-25 T 29-03-2018 A616_RS08145 102f439bc9bd8cc7043fc19528312e29 437 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 312 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 74 1.5E-13 T 29-03-2018 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 3 371 1.5E-127 T 29-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 SUPERFAMILY SSF54373 251 319 2.35E-18 T 29-03-2018 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 SUPERFAMILY SSF51971 1 269 8.95E-45 T 29-03-2018 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 SUPERFAMILY SSF51971 337 370 8.95E-45 T 29-03-2018 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 Gene3D G3DSA:3.40.50.720 1 300 7.1E-37 T 29-03-2018 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 Gene3D G3DSA:3.40.50.720 301 373 5.4E-11 T 29-03-2018 A616_RS10135 7f46b8b38aa8e5d1cefdbeace0c66e6e 373 Pfam PF03275 UDP-galactopyranose mutase 152 353 3.1E-73 T 29-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 313 4.9E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 SUPERFAMILY SSF52540 5 248 2.99E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 293 1.7E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 SMART SM00382 35 226 2.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 Gene3D G3DSA:3.40.50.300 2 315 2.9E-85 T 29-03-2018 A616_RS14790 28ed915b46a909e7f589e009f844a90c 315 Pfam PF00005 ABC transporter 27 176 1.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS06875 e2ff2c80bdf55e4f66d9e81550807eab 412 SUPERFAMILY SSF103473 12 401 1.06E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS06875 e2ff2c80bdf55e4f66d9e81550807eab 412 Pfam PF07690 Major Facilitator Superfamily 19 350 5.8E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS06875 e2ff2c80bdf55e4f66d9e81550807eab 412 Gene3D G3DSA:1.20.1250.20 204 409 5.9E-29 T 29-03-2018 A616_RS06875 e2ff2c80bdf55e4f66d9e81550807eab 412 Gene3D G3DSA:1.20.1250.20 2 190 3.5E-23 T 29-03-2018 A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 SUPERFAMILY SSF50249 6 170 6.85E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 649 3.1E-242 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 SUPERFAMILY SSF52540 439 641 3.59E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 SMART SM00490 326 404 1.3 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 SMART SM00490 491 575 4.2E-21 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 Pfam PF00270 DEAD/DEAH box helicase 261 418 8.3E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 SUPERFAMILY SSF52540 176 439 6.91E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 Gene3D G3DSA:2.40.50.140 45 141 1.3E-10 T 29-03-2018 A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 Pfam PF00271 Helicase conserved C-terminal domain 464 574 3.3E-18 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 Gene3D G3DSA:3.40.50.300 243 443 1.7E-37 T 29-03-2018 A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 Gene3D G3DSA:3.40.50.300 444 615 7.2E-32 T 29-03-2018 A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 Pfam PF17191 RecG wedge domain 10 165 4.7E-20 T 29-03-2018 IPR033454 RecG, wedge domain A616_RS20670 2ea32ef209502a31f27fa0157efaad9e 684 SMART SM00487 256 446 4.9E-35 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 1.8E-94 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 68 76 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 SUPERFAMILY SSF51658 2 285 1.31E-93 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 Gene3D G3DSA:3.20.20.150 1 297 2.9E-56 T 29-03-2018 A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 42.213 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 SMART SM00518 3 285 2.2E-114 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A616_RS01890 25979c153cb1c003a4fd5530ed265d5a 372 Pfam PF01261 Xylose isomerase-like TIM barrel 20 236 2.2E-38 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 SUPERFAMILY SSF90123 6 322 4.71E-62 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 Gene3D G3DSA:3.40.50.300 318 575 1.2E-74 T 29-03-2018 A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 SMART SM00382 361 553 7.8E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 Gene3D G3DSA:1.20.1560.10 4 317 1.0E-50 T 29-03-2018 A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 Pfam PF00005 ABC transporter 353 501 8.6E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 Pfam PF00027 Cyclic nucleotide-binding domain 598 679 1.1E-14 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 SMART SM00100 576 696 2.4E-6 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 Gene3D G3DSA:2.60.120.10 586 697 1.5E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 SUPERFAMILY SSF52540 332 571 6.58E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 SUPERFAMILY SSF51206 589 692 1.96E-18 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS09820 8dc225ea91896e91247b2303d5221dbe 697 Pfam PF00664 ABC transporter transmembrane region 20 286 6.9E-36 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 SUPERFAMILY SSF48498 76 182 8.9E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 47 8.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 SUPERFAMILY SSF46689 2 68 4.99E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 Gene3D G3DSA:1.10.357.10 55 189 5.9E-16 T 29-03-2018 A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 48 1.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27705 6c04ddb23bbe988caad8081f3029b3a1 189 Gene3D G3DSA:1.10.10.60 1 54 1.0E-13 T 29-03-2018 A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 Gene3D G3DSA:1.20.1250.20 190 388 1.5E-29 T 29-03-2018 A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 SUPERFAMILY SSF103473 3 385 4.58E-84 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 Gene3D G3DSA:1.20.1250.20 1 189 1.6E-38 T 29-03-2018 A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 Pfam PF07690 Major Facilitator Superfamily 15 253 8.4E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS25780 1e2bc7d2a0bbcbf4ed329dbce71044e4 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 260 275 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS11480 a2b22930aac10f459737e5c798d4df8d 313 PIRSF PIRSF000401 1 313 4.1E-102 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A616_RS11480 a2b22930aac10f459737e5c798d4df8d 313 SUPERFAMILY SSF53335 78 311 5.53E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS11480 a2b22930aac10f459737e5c798d4df8d 313 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 306 1.2E-84 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A616_RS11480 a2b22930aac10f459737e5c798d4df8d 313 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 312 36.114 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A616_RS11480 a2b22930aac10f459737e5c798d4df8d 313 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 312 2.3E-101 T 29-03-2018 A616_RS11480 a2b22930aac10f459737e5c798d4df8d 313 Gene3D G3DSA:3.40.50.150 117 313 4.7E-42 T 29-03-2018 A616_RS31815 184303ef68acbf8da1f7f03fe9d39e52 287 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 3.5E-98 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS31815 184303ef68acbf8da1f7f03fe9d39e52 287 PIRSF PIRSF001359 1 284 3.2E-106 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS31815 184303ef68acbf8da1f7f03fe9d39e52 287 Gene3D G3DSA:3.20.20.70 1 286 1.9E-106 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS31815 184303ef68acbf8da1f7f03fe9d39e52 287 SUPERFAMILY SSF51569 1 284 2.2E-97 T 29-03-2018 A616_RS31815 184303ef68acbf8da1f7f03fe9d39e52 287 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS31815 184303ef68acbf8da1f7f03fe9d39e52 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 283 2.1E-97 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS14515 336882127115637b79932ab265cd841b 124 SUPERFAMILY SSF52172 4 121 1.18E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS14515 336882127115637b79932ab265cd841b 124 SMART SM00448 5 116 5.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS14515 336882127115637b79932ab265cd841b 124 Pfam PF00072 Response regulator receiver domain 7 116 2.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS14515 336882127115637b79932ab265cd841b 124 Gene3D G3DSA:3.40.50.2300 1 124 4.5E-36 T 29-03-2018 A616_RS29520 1469049476d2fe7526017a0c21102e68 621 Pfam PF01973 Protein of unknown function DUF115 207 382 1.7E-34 T 29-03-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A616_RS29520 1469049476d2fe7526017a0c21102e68 621 Gene3D G3DSA:3.90.1480.10 212 543 2.9E-40 T 29-03-2018 A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 SMART SM00116 152 206 7.6E-4 T 29-03-2018 IPR000644 CBS domain A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 SMART SM00116 85 133 0.084 T 29-03-2018 IPR000644 CBS domain A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 Pfam PF00571 CBS domain 86 133 4.5E-6 T 29-03-2018 IPR000644 CBS domain A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 Pfam PF00571 CBS domain 147 206 1.4E-7 T 29-03-2018 IPR000644 CBS domain A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 SUPERFAMILY SSF46785 4 62 5.54E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 PIRSF PIRSF026546 3 212 2.6E-92 T 29-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 SUPERFAMILY SSF54631 71 207 1.18E-22 T 29-03-2018 A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 Gene3D G3DSA:3.10.580.10 63 211 3.4E-24 T 29-03-2018 A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 Gene3D G3DSA:1.10.10.10 3 62 1.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11675 ef0af76df817139e7cacc293698f6e5c 214 Pfam PF08279 HTH domain 8 60 1.9E-12 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 SMART SM00345 8 67 1.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 Gene3D G3DSA:3.90.1150.10 347 444 1.7E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 Gene3D G3DSA:3.40.640.10 102 346 3.6E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 SUPERFAMILY SSF53383 55 441 1.28E-80 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 SUPERFAMILY SSF46785 3 77 1.09E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 Gene3D G3DSA:1.10.10.10 1 67 4.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25655 1aae3690fa0b9849c91647020aacb977 460 Pfam PF00155 Aminotransferase class I and II 109 432 2.9E-23 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS01530 afff5ff3be201be153034212bb224278 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 130 8.6E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01530 afff5ff3be201be153034212bb224278 133 SUPERFAMILY SSF53137 18 133 3.2E-50 T 29-03-2018 A616_RS01530 afff5ff3be201be153034212bb224278 133 Gene3D G3DSA:3.30.420.80 9 133 2.6E-46 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A616_RS01530 afff5ff3be201be153034212bb224278 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site A616_RS01530 afff5ff3be201be153034212bb224278 133 PIRSF PIRSF002131 1 133 9.2E-54 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A616_RS01530 afff5ff3be201be153034212bb224278 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 133 34.475 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A616_RS01530 afff5ff3be201be153034212bb224278 133 Pfam PF00411 Ribosomal protein S11 23 132 2.7E-51 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 Hamap MF_00384 Homoserine kinase [thrB]. 6 304 32.132 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 PRINTS PR00958 Homoserine kinase signature 129 142 1.8E-37 T 29-03-2018 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 PRINTS PR00958 Homoserine kinase signature 250 265 1.8E-37 T 29-03-2018 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 PRINTS PR00958 Homoserine kinase signature 95 110 1.8E-37 T 29-03-2018 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 PRINTS PR00958 Homoserine kinase signature 13 28 1.8E-37 T 29-03-2018 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 PRINTS PR00958 Homoserine kinase signature 171 188 1.8E-37 T 29-03-2018 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 Pfam PF08544 GHMP kinases C terminal 207 283 2.4E-13 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 Gene3D G3DSA:3.30.230.10 4 152 1.5E-30 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 SUPERFAMILY SSF54211 5 149 1.44E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 PIRSF PIRSF000676 2 307 2.3E-91 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 Gene3D G3DSA:3.30.70.890 163 309 6.2E-33 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 TIGRFAM TIGR00191 thrB: homoserine kinase 6 305 1.6E-83 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 SUPERFAMILY SSF55060 168 280 1.41E-33 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain A616_RS10610 095afbb86439d9075ad072f3d93f6533 309 Pfam PF00288 GHMP kinases N terminal domain 82 142 1.2E-9 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A616_RS08870 8e467d4e5e3008a3b4f4575a4db80c83 268 SUPERFAMILY SSF56784 2 215 5.02E-14 T 29-03-2018 IPR023214 HAD-like domain A616_RS08870 8e467d4e5e3008a3b4f4575a4db80c83 268 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 2 220 4.1E-7 T 29-03-2018 IPR006380 Sucrose-phosphatase-like, N-terminal A616_RS08870 8e467d4e5e3008a3b4f4575a4db80c83 268 Gene3D G3DSA:3.40.50.1000 1 229 5.1E-8 T 29-03-2018 IPR023214 HAD-like domain A616_RS08870 8e467d4e5e3008a3b4f4575a4db80c83 268 PIRSF PIRSF030802 1 239 2.0E-14 T 29-03-2018 IPR024197 Uncharacterised conserved protein UCP030802 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 SMART SM00650 40 216 1.7E-81 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 24 288 1.5E-85 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 288 4.7E-72 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 24 291 54.347 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 56 83 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 Gene3D G3DSA:3.40.50.150 6 225 1.5E-60 T 29-03-2018 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 Gene3D G3DSA:1.10.8.100 226 289 2.2E-22 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A616_RS00640 0d042ad4cee6269f88aeb5c83d077930 297 SUPERFAMILY SSF53335 21 289 1.99E-74 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10265 74d98931816b219769004eee7938789d 270 Gene3D G3DSA:3.40.50.1860 3 117 1.2E-27 T 29-03-2018 A616_RS10265 74d98931816b219769004eee7938789d 270 SUPERFAMILY SSF53681 110 261 2.62E-38 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10265 74d98931816b219769004eee7938789d 270 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 216 8.7E-35 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10265 74d98931816b219769004eee7938789d 270 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10265 74d98931816b219769004eee7938789d 270 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 253 1.2E-82 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10265 74d98931816b219769004eee7938789d 270 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10265 74d98931816b219769004eee7938789d 270 Hamap MF_00258 Glutamate racemase [murI]. 5 256 39.039 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS10265 74d98931816b219769004eee7938789d 270 Gene3D G3DSA:3.40.50.1860 118 267 6.2E-42 T 29-03-2018 A616_RS10265 74d98931816b219769004eee7938789d 270 SUPERFAMILY SSF53681 6 108 2.42E-33 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS18110 f866ef7b88c7cc01fecd251219ffb9a2 433 Gene3D G3DSA:3.60.21.10 5 350 2.7E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS18110 f866ef7b88c7cc01fecd251219ffb9a2 433 SMART SM00854 6 317 2.4E-56 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS18110 f866ef7b88c7cc01fecd251219ffb9a2 433 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 8 316 3.5E-65 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS18110 f866ef7b88c7cc01fecd251219ffb9a2 433 SUPERFAMILY SSF56300 224 332 1.45E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS18110 f866ef7b88c7cc01fecd251219ffb9a2 433 SUPERFAMILY SSF56300 8 139 1.45E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10525 d3d179e2b0ef5a14c00c2c9096afa490 376 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 13 370 3.5E-102 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 A616_RS10525 d3d179e2b0ef5a14c00c2c9096afa490 376 Pfam PF01098 Cell cycle protein 38 370 1.3E-83 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A616_RS12550 a30dec5b5698c80b8b4d23694f68039f 319 SUPERFAMILY SSF48452 173 275 8.22E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12550 a30dec5b5698c80b8b4d23694f68039f 319 SUPERFAMILY SSF48452 41 139 8.22E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12550 a30dec5b5698c80b8b4d23694f68039f 319 Gene3D G3DSA:1.25.40.10 159 278 2.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12550 a30dec5b5698c80b8b4d23694f68039f 319 Gene3D G3DSA:1.25.40.10 36 158 3.0E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS20415 6c774725650f28c6d354ed400ccd99ba 300 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 254 3.9E-79 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain A616_RS07975 82522c0b5e31e6869728cbca06100aa7 143 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 116 7.4E-31 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A616_RS07975 82522c0b5e31e6869728cbca06100aa7 143 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 11 28 - T 29-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 A616_RS07975 82522c0b5e31e6869728cbca06100aa7 143 Pfam PF03061 Thioesterase superfamily 20 101 2.1E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS07975 82522c0b5e31e6869728cbca06100aa7 143 PIRSF PIRSF003230 1 134 2.5E-46 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A616_RS07975 82522c0b5e31e6869728cbca06100aa7 143 Gene3D G3DSA:3.10.129.10 3 140 3.4E-39 T 29-03-2018 A616_RS07975 82522c0b5e31e6869728cbca06100aa7 143 SUPERFAMILY SSF54637 3 131 1.79E-40 T 29-03-2018 IPR029069 HotDog domain A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 Gene3D G3DSA:1.10.10.10 146 201 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 2.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 2.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 2.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 196 3.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 SMART SM00421 139 196 6.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 SUPERFAMILY SSF52172 3 128 4.98E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 Pfam PF00072 Response regulator receiver domain 6 115 2.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 SMART SM00448 4 115 4.2E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 Gene3D G3DSA:3.40.50.2300 3 145 5.6E-33 T 29-03-2018 A616_RS25500 2eb04de3812a733a24d402eb15d27a94 203 SUPERFAMILY SSF46894 137 201 5.44E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 Gene3D G3DSA:3.40.190.10 93 180 5.8E-17 T 29-03-2018 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 Gene3D G3DSA:3.40.190.10 181 263 1.2E-18 T 29-03-2018 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 Gene3D G3DSA:1.10.10.10 1 92 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 SUPERFAMILY SSF53850 87 294 5.36E-38 T 29-03-2018 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 Pfam PF03466 LysR substrate binding domain 87 294 8.2E-39 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 SUPERFAMILY SSF46785 1 111 8.18E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27290 f0f40d1d782e1bcda7680cfe0bbcc338 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 Pfam PF08281 Sigma-70, region 4 104 154 2.8E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 154 2.2E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 SUPERFAMILY SSF88659 78 154 1.14E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 SUPERFAMILY SSF88946 2 86 5.1E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 Gene3D G3DSA:3.10.450.50 146 280 1.1E-6 T 29-03-2018 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 Gene3D G3DSA:1.10.1740.10 1 68 2.4E-14 T 29-03-2018 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 Gene3D G3DSA:1.10.10.10 69 145 2.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 Pfam PF04542 Sigma-70 region 2 4 69 5.7E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 SUPERFAMILY SSF54427 167 278 4.6E-10 T 29-03-2018 IPR032710 NTF2-like domain A616_RS28280 316d6e85434731e95de4ca0cfedd48c7 283 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 4 279 8.4E-101 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type A616_RS07470 cc38d9a268bdca35b75cbfcf64546073 662 Gene3D G3DSA:3.40.710.10 44 387 4.5E-76 T 29-03-2018 A616_RS07470 cc38d9a268bdca35b75cbfcf64546073 662 Pfam PF00144 Beta-lactamase 55 372 3.5E-62 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS07470 cc38d9a268bdca35b75cbfcf64546073 662 SUPERFAMILY SSF56601 50 370 6.13E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS07470 cc38d9a268bdca35b75cbfcf64546073 662 Pfam PF00395 S-layer homology domain 495 537 2.3E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS07470 cc38d9a268bdca35b75cbfcf64546073 662 Pfam PF00395 S-layer homology domain 604 645 0.014 T 29-03-2018 IPR001119 S-layer homology domain A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 PRINTS PR00419 Adrenodoxin reductase family signature 130 152 4.5E-19 T 29-03-2018 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 PRINTS PR00419 Adrenodoxin reductase family signature 195 205 4.5E-19 T 29-03-2018 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 PRINTS PR00419 Adrenodoxin reductase family signature 153 166 4.5E-19 T 29-03-2018 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 PRINTS PR00419 Adrenodoxin reductase family signature 263 277 4.5E-19 T 29-03-2018 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 SUPERFAMILY SSF51971 127 373 7.06E-62 T 29-03-2018 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 129 427 2.5E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Gene3D G3DSA:3.50.50.60 373 447 1.6E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 9 117 3.8E-38 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Gene3D G3DSA:3.50.50.60 288 372 8.5E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Gene3D G3DSA:3.50.50.60 221 287 9.3E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Gene3D G3DSA:3.40.50.720 123 220 3.5E-22 T 29-03-2018 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 SUPERFAMILY SSF46548 5 139 3.45E-30 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS18730 c41241c57e01d641ad44e196a32ef561 448 Gene3D G3DSA:1.10.1060.10 1 122 9.6E-36 T 29-03-2018 A616_RS08670 8ca08b9e7762d55be31fc383206ef38b 163 Pfam PF03703 Bacterial PH domain 77 153 1.1E-16 T 29-03-2018 IPR005182 Domain of unknown function DUF304 A616_RS27430 d0bad6238f0cee0406775d8fddb71d7d 277 Pfam PF05138 Phenylacetic acid catabolic protein 16 277 5.7E-66 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A616_RS27430 d0bad6238f0cee0406775d8fddb71d7d 277 Gene3D G3DSA:1.20.1260.10 12 277 2.2E-58 T 29-03-2018 IPR012347 Ferritin-related A616_RS27430 d0bad6238f0cee0406775d8fddb71d7d 277 PIRSF PIRSF037834 12 277 9.8E-88 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A616_RS27430 d0bad6238f0cee0406775d8fddb71d7d 277 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 30 277 5.0E-76 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 A616_RS27430 d0bad6238f0cee0406775d8fddb71d7d 277 SUPERFAMILY SSF47240 20 270 2.78E-58 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 8 368 3.6E-142 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 SUPERFAMILY SSF53187 7 179 1.36E-64 T 29-03-2018 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 SUPERFAMILY SSF53187 289 371 1.36E-64 T 29-03-2018 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 Pfam PF07687 Peptidase dimerisation domain 177 275 1.4E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 144 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 SUPERFAMILY SSF55031 179 288 1.31E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 Pfam PF01546 Peptidase family M20/M25/M40 74 369 6.8E-23 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 Gene3D G3DSA:3.40.630.10 1 373 2.3E-66 T 29-03-2018 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 PIRSF PIRSF001123 6 97 1.7E-4 T 29-03-2018 IPR008007 Peptidase M42 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 PIRSF PIRSF001123 82 184 4.5E-5 T 29-03-2018 IPR008007 Peptidase M42 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 PIRSF PIRSF001123 258 373 0.22 T 29-03-2018 IPR008007 Peptidase M42 A616_RS13300 ff1d405e61e0767e93b3d3eece129cff 373 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS07305 2ca0a1d4fa587b6fe4e72a530de309cd 246 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 246 44.747 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07305 2ca0a1d4fa587b6fe4e72a530de309cd 246 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 3 240 1.7E-40 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07305 2ca0a1d4fa587b6fe4e72a530de309cd 246 Pfam PF02654 Cobalamin-5-phosphate synthase 7 238 4.8E-58 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 332 29.165 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 30 143 8.1E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 Gene3D G3DSA:3.30.1330.10 1 149 3.0E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 SUPERFAMILY SSF55326 5 144 2.09E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 Gene3D G3DSA:3.90.650.10 150 335 4.8E-44 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 335 1.7E-99 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 PIRSF PIRSF005303 2 335 3.3E-99 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 SUPERFAMILY SSF56042 147 311 7.63E-35 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS02940 80f2ca0e015dda93d9e22a9728cef217 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 155 312 9.0E-14 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 Gene3D G3DSA:3.40.50.300 1 243 1.5E-48 T 29-03-2018 A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 SUPERFAMILY SSF52540 270 486 2.99E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 Pfam PF00005 ABC transporter 19 172 4.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 Pfam PF00005 ABC transporter 271 424 3.2E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 Gene3D G3DSA:3.40.50.300 260 493 3.9E-36 T 29-03-2018 A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 SUPERFAMILY SSF52540 4 228 4.15E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 SMART SM00382 28 228 4.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28195 706723f5792e375ad818d179a9bc2d00 496 SMART SM00382 279 480 0.0025 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00690 Adhesin family signature 36 54 6.2E-53 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00690 Adhesin family signature 80 97 6.2E-53 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00690 Adhesin family signature 67 80 6.2E-53 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00690 Adhesin family signature 277 296 6.2E-53 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00690 Adhesin family signature 198 219 6.2E-53 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00690 Adhesin family signature 251 269 6.2E-53 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 309 8.2E-80 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 Gene3D G3DSA:3.40.50.1980 25 190 3.5E-48 T 29-03-2018 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 Gene3D G3DSA:3.40.50.1980 191 312 3.0E-35 T 29-03-2018 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 SUPERFAMILY SSF53807 35 311 3.24E-87 T 29-03-2018 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 269 287 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 61 79 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 290 308 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 198 215 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 224 242 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 247 264 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 36 57 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 80 99 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS08565 c9ee37b585fc7ccbd097fa484e3eefe3 314 PRINTS PR00691 Adhesin B signature 140 159 1.2E-78 T 29-03-2018 IPR006129 Adhesin B GO:0007155 A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 Pfam PF04055 Radical SAM superfamily 26 147 2.5E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 Pfam PF13353 4Fe-4S single cluster domain 12 114 7.2E-9 T 29-03-2018 A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 PIRSF PIRSF000370 1 239 7.7E-52 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 2 239 1.1E-114 T 29-03-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 SUPERFAMILY SSF102114 24 111 4.45E-13 T 29-03-2018 A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 Gene3D G3DSA:3.80.30.20 19 217 1.1E-18 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A616_RS25340 c06d60da8e05c972121aff65bf7be634 239 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 2 236 36.118 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A616_RS29255 fa67b429dc76f3c31c06681dbeca9b3e 209 Pfam PF01966 HD domain 33 132 1.0E-14 T 29-03-2018 IPR006674 HD domain A616_RS29255 fa67b429dc76f3c31c06681dbeca9b3e 209 SUPERFAMILY SSF109604 18 206 1.28E-51 T 29-03-2018 A616_RS29255 fa67b429dc76f3c31c06681dbeca9b3e 209 SMART SM00471 27 143 1.3E-12 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS29255 fa67b429dc76f3c31c06681dbeca9b3e 209 Gene3D G3DSA:1.10.3210.10 14 208 4.2E-28 T 29-03-2018 A616_RS29255 fa67b429dc76f3c31c06681dbeca9b3e 209 TIGRFAM TIGR00277 HDIG: HDIG domain 33 85 4.7E-10 T 29-03-2018 IPR006675 HDIG domain A616_RS11900 3f0210d7754337e5eda0dfdb0643d677 467 SUPERFAMILY SSF53448 54 360 3.09E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS11900 3f0210d7754337e5eda0dfdb0643d677 467 Pfam PF13641 Glycosyltransferase like family 2 56 325 1.9E-22 T 29-03-2018 A616_RS11900 3f0210d7754337e5eda0dfdb0643d677 467 Gene3D G3DSA:3.90.550.10 43 340 2.5E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Gene3D G3DSA:3.20.20.330 1 317 3.2E-100 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 913 1142 4.7E-57 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 TIGRFAM TIGR02082 metH: methionine synthase 9 1140 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Gene3D G3DSA:3.10.196.10 922 1145 5.1E-63 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 SMART SM01018 622 704 1.2E-36 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Gene3D G3DSA:3.40.50.280 705 856 1.3E-49 T 29-03-2018 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Pfam PF02607 B12 binding domain 625 697 8.1E-21 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 SUPERFAMILY SSF51717 335 597 4.19E-79 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 SUPERFAMILY SSF56507 867 1142 5.49E-86 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 SUPERFAMILY SSF82282 1 377 1.83E-111 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Gene3D G3DSA:1.10.1240.10 614 704 3.0E-27 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 ProDom PD009948 METHYLTRANSFERASE SUBUNIT H TRANSFERASE M TETRAHYDROMETHANOPTERIN S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS ONE-CARBON 389 514 0.005 T 29-03-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 PIRSF PIRSF000381 1 1143 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Gene3D G3DSA:3.20.20.20 323 613 2.6E-54 T 29-03-2018 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Pfam PF02574 Homocysteine S-methyltransferase 14 304 1.1E-74 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Pfam PF00809 Pterin binding enzyme 338 571 7.9E-43 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 SUPERFAMILY SSF52242 705 846 9.81E-42 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 Pfam PF02310 B12 binding domain 710 805 1.2E-19 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS12425 6891df4e58c13eb573d00c7fd8ef5cd4 1148 SUPERFAMILY SSF47644 619 703 1.83E-22 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS09385 312334870420eea14039e3f20ec745c9 603 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 301 458 3.7E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS09385 312334870420eea14039e3f20ec745c9 603 Gene3D G3DSA:2.40.110.10 187 300 2.2E-20 T 29-03-2018 A616_RS09385 312334870420eea14039e3f20ec745c9 603 Gene3D G3DSA:1.10.540.10 40 182 0.0017 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS09385 312334870420eea14039e3f20ec745c9 603 Gene3D G3DSA:1.20.140.10 301 469 8.1E-39 T 29-03-2018 A616_RS09385 312334870420eea14039e3f20ec745c9 603 SUPERFAMILY SSF56645 67 309 3.24E-36 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS09385 312334870420eea14039e3f20ec745c9 603 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 188 289 5.9E-14 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS09385 312334870420eea14039e3f20ec745c9 603 SUPERFAMILY SSF47203 298 463 2.26E-41 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS09385 312334870420eea14039e3f20ec745c9 603 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 417 436 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 Pfam PF12800 4Fe-4S binding domain 10 24 0.091 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 Gene3D G3DSA:3.30.70.20 70 105 1.1E-14 T 29-03-2018 A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 Gene3D G3DSA:3.30.70.20 1 19 0.0091 T 29-03-2018 A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 Gene3D G3DSA:3.30.70.20 106 176 1.3E-11 T 29-03-2018 A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 SUPERFAMILY SSF54862 5 157 2.41E-41 T 29-03-2018 A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 Gene3D G3DSA:3.30.70.20 20 69 1.1E-8 T 29-03-2018 A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 Pfam PF13247 4Fe-4S dicluster domain 48 138 3.0E-22 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS26120 79f2c016e2290a22fbe020f0a00e4cfb 189 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS10810 79205bb9ba82b4d94fd1e3f890b0b2ec 159 SUPERFAMILY SSF50346 92 158 2.83E-9 T 29-03-2018 IPR011033 PRC-barrel-like A616_RS10810 79205bb9ba82b4d94fd1e3f890b0b2ec 159 Gene3D G3DSA:2.30.30.240 91 159 1.9E-8 T 29-03-2018 A616_RS10810 79205bb9ba82b4d94fd1e3f890b0b2ec 159 Gene3D G3DSA:2.30.30.240 1 72 3.5E-9 T 29-03-2018 A616_RS10810 79205bb9ba82b4d94fd1e3f890b0b2ec 159 Pfam PF05239 PRC-barrel domain 92 157 8.4E-8 T 29-03-2018 IPR027275 PRC-barrel domain A616_RS10810 79205bb9ba82b4d94fd1e3f890b0b2ec 159 Pfam PF05239 PRC-barrel domain 7 62 1.3E-5 T 29-03-2018 IPR027275 PRC-barrel domain A616_RS10810 79205bb9ba82b4d94fd1e3f890b0b2ec 159 SUPERFAMILY SSF50346 6 66 2.09E-7 T 29-03-2018 IPR011033 PRC-barrel-like A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 SUPERFAMILY SSF51735 54 296 1.38E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 Gene3D G3DSA:3.40.50.720 8 298 1.4E-69 T 29-03-2018 A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 191 219 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 65 294 2.9E-59 T 29-03-2018 A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 184 192 1.7E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 204 223 1.7E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 143 1.7E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 57 74 5.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 223 5.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 143 5.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 259 279 5.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 242 5.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26085 db024c61357c532dda5b3d5f6f724b56 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 194 5.3E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 Pfam PF03466 LysR substrate binding domain 88 285 1.6E-42 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 Gene3D G3DSA:3.40.190.10 174 261 1.5E-21 T 29-03-2018 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 SUPERFAMILY SSF46785 1 87 6.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 Gene3D G3DSA:3.40.190.10 92 173 8.6E-20 T 29-03-2018 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 SUPERFAMILY SSF53850 89 290 2.49E-40 T 29-03-2018 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.1E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09225 d6a6de245ab8b87e75d86495700c2d5b 295 Gene3D G3DSA:1.10.10.10 1 91 1.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 Gene3D G3DSA:1.10.10.60 466 519 1.5E-15 T 29-03-2018 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 Gene3D G3DSA:2.60.120.10 240 465 4.9E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 SUPERFAMILY SSF52172 1 133 2.28E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 SUPERFAMILY SSF46689 463 514 1.08E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 SUPERFAMILY SSF46689 411 461 2.51E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 SMART SM00342 427 510 1.3E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 Pfam PF00072 Response regulator receiver domain 5 116 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 SMART SM00448 2 116 4.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 Gene3D G3DSA:3.40.50.2300 1 216 2.0E-35 T 29-03-2018 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 Pfam PF12833 Helix-turn-helix domain 434 512 2.6E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS24825 707e3485d1799dac2880820d06ac6a76 520 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 464 506 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 451 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 484 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 465 1.3E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 SUPERFAMILY SSF47384 285 355 6.08E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 SMART SM00388 290 355 4.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 351 5.5E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 SUPERFAMILY SSF55874 366 504 4.85E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 Pfam PF13426 PAS domain 182 274 4.0E-8 T 29-03-2018 IPR000014 PAS domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 506 1.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 SMART SM00091 170 236 5.9E-8 T 29-03-2018 IPR000014 PAS domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 Gene3D G3DSA:3.30.450.20 158 283 5.0E-20 T 29-03-2018 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 Gene3D G3DSA:1.10.287.130 284 351 1.8E-16 T 29-03-2018 A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 Gene3D G3DSA:3.30.565.10 359 508 1.1E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 SMART SM00387 399 507 2.0E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 SUPERFAMILY SSF55785 182 282 1.92E-16 T 29-03-2018 IPR000014 PAS domain A616_RS18635 750d5b550446abb0ae1b3ccdc370c30e 508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 169 282 1.7E-12 T 29-03-2018 IPR000014 PAS domain A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 Gene3D G3DSA:1.10.10.10 33 116 4.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 Pfam PF12802 MarR family 41 99 6.7E-9 T 29-03-2018 A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 SMART SM00347 35 136 1.2E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 SUPERFAMILY SSF46785 14 149 5.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 Gene3D G3DSA:1.10.287.100 117 151 5.6E-5 T 29-03-2018 A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04740 6c7d20e15baaab015953b4c2c48893f1 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 1.7E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS27405 779789f51358f58c051b069ae34a1c9d 152 Gene3D G3DSA:1.20.120.80 1 138 6.7E-12 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27405 779789f51358f58c051b069ae34a1c9d 152 Pfam PF04238 Protein of unknown function (DUF420) 5 133 2.1E-39 T 29-03-2018 IPR007352 Protein of unknown function DUF420 A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 2.3E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 1.7E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 SMART SM00382 34 233 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 Gene3D G3DSA:3.40.50.300 2 321 4.0E-75 T 29-03-2018 A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 SUPERFAMILY SSF52540 5 253 2.84E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15480 44d9586064bf5e61945c905cfc0a372f 321 Pfam PF00005 ABC transporter 26 183 3.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS17820 620a69a4ea4456a843770dc33ea5b17d 255 SUPERFAMILY SSF51621 3 249 1.88E-57 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS17820 620a69a4ea4456a843770dc33ea5b17d 255 Gene3D G3DSA:3.20.20.60 1 253 4.7E-52 T 29-03-2018 A616_RS17820 620a69a4ea4456a843770dc33ea5b17d 255 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 244 1.4E-66 T 29-03-2018 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SUPERFAMILY SSF55874 903 1042 7.99E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Pfam PF07695 7TM diverse intracellular signalling 235 436 8.6E-12 T 29-03-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Gene3D G3DSA:3.30.565.10 521 682 5.9E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Pfam PF00072 Response regulator receiver domain 719 832 2.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Pfam PF00512 His Kinase A (phospho-acceptor) domain 459 526 6.2E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SUPERFAMILY SSF55874 516 680 1.05E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Gene3D G3DSA:3.30.565.10 915 1050 3.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SUPERFAMILY SSF52172 712 847 1.85E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Gene3D G3DSA:3.40.50.2300 709 914 2.5E-35 T 29-03-2018 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Gene3D G3DSA:1.10.287.130 448 520 4.3E-11 T 29-03-2018 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Gene3D G3DSA:2.60.120.260 66 211 5.4E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Pfam PF06580 Histidine kinase 848 926 5.1E-21 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 661 4.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 PRINTS PR00344 Bacterial sensor protein C-terminal signature 607 621 4.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 PRINTS PR00344 Bacterial sensor protein C-terminal signature 625 635 4.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 681 4.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SMART SM00388 458 526 2.5E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 572 681 1.7E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 948 1043 1.7E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SMART SM00448 717 831 7.6E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SMART SM00387 571 684 3.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SMART SM00387 938 1045 0.3 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24230 a7129f3677423772efcdf3e56a6ada4d 1052 SUPERFAMILY SSF47384 448 527 2.75E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 SUPERFAMILY SSF56176 4 212 3.69E-68 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 Gene3D G3DSA:1.10.45.10 413 451 2.4E-14 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 SUPERFAMILY SSF55103 215 452 2.29E-66 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 Gene3D G3DSA:3.30.465.10 91 234 2.5E-43 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 Pfam PF01565 FAD binding domain 38 175 2.1E-40 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 Pfam PF02913 FAD linked oxidases, C-terminal domain 211 451 6.9E-60 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A616_RS30915 5ad99f2df77fdb0f4fdb5eea6b32436a 454 Gene3D G3DSA:3.30.43.10 2 90 7.1E-26 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A616_RS23075 773ed8af0bd7d5018439379727ada718 402 SUPERFAMILY SSF53383 4 393 5.24E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS23075 773ed8af0bd7d5018439379727ada718 402 Gene3D G3DSA:3.90.1150.10 299 395 5.8E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS23075 773ed8af0bd7d5018439379727ada718 402 Pfam PF00155 Aminotransferase class I and II 37 387 6.0E-40 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS23075 773ed8af0bd7d5018439379727ada718 402 Gene3D G3DSA:3.40.640.10 44 298 2.9E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 SUPERFAMILY SSF53474 436 451 4.01E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 SUPERFAMILY SSF53474 528 786 4.01E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 Pfam PF02450 Lecithin:cholesterol acyltransferase 459 878 2.3E-73 T 29-03-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 351 416 5.3E-6 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 Gene3D G3DSA:2.60.120.380 189 310 2.2E-13 T 29-03-2018 A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 Gene3D G3DSA:3.40.50.1820 436 792 3.2E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 SUPERFAMILY SSF89260 196 298 5.89E-7 T 29-03-2018 A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 SUPERFAMILY SSF89260 320 422 7.59E-14 T 29-03-2018 A616_RS30245 73a2b9d6f61fdec7cb27d9207c0d5622 920 Gene3D G3DSA:2.60.120.380 314 435 3.6E-17 T 29-03-2018 A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 PRINTS PR01713 Nucleotide sugar epimerase signature 282 299 7.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 7.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 PRINTS PR01713 Nucleotide sugar epimerase signature 239 254 7.3E-6 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 Gene3D G3DSA:3.90.25.10 194 334 1.3E-33 T 29-03-2018 A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 Gene3D G3DSA:3.40.50.720 1 193 6.6E-44 T 29-03-2018 A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 310 1.1E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 9 303 2.1E-163 T 29-03-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family A616_RS29515 61ad9d6d59dfcc5f6b92b55207e975fb 336 SUPERFAMILY SSF51735 2 323 8.28E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS00515 19607d97556cad36a339216620fac70f 103 PIRSF PIRSF004555 1 103 4.5E-37 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A616_RS00515 19607d97556cad36a339216620fac70f 103 Gene3D G3DSA:3.30.1310.10 1 103 3.0E-37 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A616_RS00515 19607d97556cad36a339216620fac70f 103 SUPERFAMILY SSF82607 8 102 1.31E-32 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A616_RS00515 19607d97556cad36a339216620fac70f 103 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 22.542 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A616_RS00515 19607d97556cad36a339216620fac70f 103 Pfam PF02575 YbaB/EbfC DNA-binding family 8 98 9.3E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A616_RS00515 19607d97556cad36a339216620fac70f 103 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 102 3.5E-28 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A616_RS30055 4b813ef2372f25294721782c4b068048 191 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 33.462 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS30055 4b813ef2372f25294721782c4b068048 191 SUPERFAMILY SSF52540 2 139 5.31E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30055 4b813ef2372f25294721782c4b068048 191 SUPERFAMILY SSF57716 140 187 4.42E-12 T 29-03-2018 A616_RS30055 4b813ef2372f25294721782c4b068048 191 Gene3D G3DSA:3.40.50.300 2 139 3.3E-45 T 29-03-2018 A616_RS30055 4b813ef2372f25294721782c4b068048 191 Gene3D G3DSA:3.30.60.20 140 189 2.0E-15 T 29-03-2018 A616_RS30055 4b813ef2372f25294721782c4b068048 191 PIRSF PIRSF035805 1 190 2.8E-60 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS30055 4b813ef2372f25294721782c4b068048 191 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 29-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS30055 4b813ef2372f25294721782c4b068048 191 Pfam PF00265 Thymidine kinase 2 184 1.3E-48 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 Pfam PF05225 helix-turn-helix, Psq domain 504 540 2.0E-4 T 29-03-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SUPERFAMILY SSF48452 156 323 1.36E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SMART SM00028 291 324 8.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SMART SM00028 154 187 320.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SMART SM00028 54 87 340.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SMART SM00028 20 53 1.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SMART SM00028 89 122 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SMART SM00028 188 221 0.21 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 Gene3D G3DSA:1.25.40.10 152 271 6.6E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 Gene3D G3DSA:1.25.40.10 10 141 8.1E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 SUPERFAMILY SSF48452 16 137 7.34E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 Pfam PF14559 Tetratricopeptide repeat 165 220 5.9E-6 T 29-03-2018 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 Pfam PF13432 Tetratricopeptide repeat 35 73 0.0032 T 29-03-2018 A616_RS29155 da29429c53f6fbe8eb4b44af07f1e337 547 Gene3D G3DSA:1.25.40.10 272 430 3.0E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS00795 771a12209da2e05bcf0ba4e00f97b8f8 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 1.0E-67 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 A616_RS00795 771a12209da2e05bcf0ba4e00f97b8f8 179 Pfam PF00156 Phosphoribosyl transferase domain 10 159 4.9E-27 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS00795 771a12209da2e05bcf0ba4e00f97b8f8 179 Gene3D G3DSA:3.40.50.2020 1 179 5.0E-49 T 29-03-2018 A616_RS00795 771a12209da2e05bcf0ba4e00f97b8f8 179 SUPERFAMILY SSF53271 3 177 2.88E-61 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS05280 20ae980dd0b5831307294dc59e92d872 309 Gene3D G3DSA:1.10.340.30 125 246 8.3E-34 T 29-03-2018 A616_RS05280 20ae980dd0b5831307294dc59e92d872 309 SMART SM00478 134 299 8.5E-23 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS05280 20ae980dd0b5831307294dc59e92d872 309 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 130 284 3.5E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS05280 20ae980dd0b5831307294dc59e92d872 309 Gene3D G3DSA:3.30.310.20 5 124 1.0E-7 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal A616_RS05280 20ae980dd0b5831307294dc59e92d872 309 Gene3D G3DSA:1.10.1670.10 249 304 3.3E-12 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A616_RS05280 20ae980dd0b5831307294dc59e92d872 309 SUPERFAMILY SSF48150 113 295 2.09E-46 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A616_RS24570 ad55561f51b7183adac180d02f30408f 605 SUPERFAMILY SSF48452 293 492 1.27E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS24570 ad55561f51b7183adac180d02f30408f 605 Gene3D G3DSA:1.20.120.420 266 356 0.025 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A616_RS24570 ad55561f51b7183adac180d02f30408f 605 Gene3D G3DSA:3.60.40.10 2 247 2.7E-14 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS24570 ad55561f51b7183adac180d02f30408f 605 Gene3D G3DSA:1.25.40.10 357 449 0.0018 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS24570 ad55561f51b7183adac180d02f30408f 605 SUPERFAMILY SSF81606 20 239 1.44E-21 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS24570 ad55561f51b7183adac180d02f30408f 605 Gene3D G3DSA:1.20.58.280 450 514 9.0E-4 T 29-03-2018 A616_RS21235 901b13d43d9ca8102603ac7907bb4246 92 Pfam PF05239 PRC-barrel domain 2 75 4.6E-15 T 29-03-2018 IPR027275 PRC-barrel domain A616_RS21235 901b13d43d9ca8102603ac7907bb4246 92 SUPERFAMILY SSF50346 1 74 1.83E-15 T 29-03-2018 IPR011033 PRC-barrel-like A616_RS21235 901b13d43d9ca8102603ac7907bb4246 92 Gene3D G3DSA:2.30.30.240 1 79 7.0E-19 T 29-03-2018 A616_RS21235 901b13d43d9ca8102603ac7907bb4246 92 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 75 4.1E-27 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH A616_RS17430 e7e0db1e69649191ad2d3c2f90fa2861 334 Pfam PF00589 Phage integrase family 148 320 4.1E-9 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS17430 e7e0db1e69649191ad2d3c2f90fa2861 334 SUPERFAMILY SSF56349 33 322 2.94E-25 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS17430 e7e0db1e69649191ad2d3c2f90fa2861 334 Gene3D G3DSA:1.10.443.10 146 333 1.4E-15 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS17430 e7e0db1e69649191ad2d3c2f90fa2861 334 Gene3D G3DSA:1.10.150.130 26 116 1.6E-14 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS17430 e7e0db1e69649191ad2d3c2f90fa2861 334 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 37 112 5.7E-8 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS08740 521e2d2302e649e000c6ccce710927dd 243 SMART SM00382 33 228 3.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08740 521e2d2302e649e000c6ccce710927dd 243 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08740 521e2d2302e649e000c6ccce710927dd 243 Gene3D G3DSA:3.40.50.300 1 241 2.3E-67 T 29-03-2018 A616_RS08740 521e2d2302e649e000c6ccce710927dd 243 Pfam PF00005 ABC transporter 24 172 5.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08740 521e2d2302e649e000c6ccce710927dd 243 SUPERFAMILY SSF52540 4 229 3.41E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21870 3f9cbce6a92560687ec22dbecb9bd18d 197 SUPERFAMILY SSF55469 5 178 8.77E-33 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS21870 3f9cbce6a92560687ec22dbecb9bd18d 197 Pfam PF00881 Nitroreductase family 12 157 7.5E-24 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS21870 3f9cbce6a92560687ec22dbecb9bd18d 197 PIRSF PIRSF000232 6 183 4.9E-37 T 29-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like A616_RS21870 3f9cbce6a92560687ec22dbecb9bd18d 197 Gene3D G3DSA:3.40.109.10 1 180 1.8E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Gene3D G3DSA:1.10.287.950 323 435 6.4E-10 T 29-03-2018 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Gene3D G3DSA:1.10.287.950 436 684 7.5E-55 T 29-03-2018 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Gene3D G3DSA:3.30.450.20 184 303 3.2E-22 T 29-03-2018 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 SMART SM00283 386 682 1.6E-72 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Pfam PF00672 HAMP domain 327 375 2.5E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Gene3D G3DSA:3.30.450.20 76 183 3.2E-17 T 29-03-2018 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 SMART SM00304 326 378 8.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 SUPERFAMILY SSF103190 213 262 4.71E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 SUPERFAMILY SSF103190 77 207 8.63E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 454 635 1.9E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 Pfam PF02743 Cache domain 38 288 2.3E-24 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 SUPERFAMILY SSF58104 346 380 1.83E-70 T 29-03-2018 A616_RS26810 89a9514dbf77e06888300978ae8a7d90 684 SUPERFAMILY SSF58104 413 682 1.83E-70 T 29-03-2018 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 Pfam PF00403 Heavy-metal-associated domain 4 65 4.2E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 SUPERFAMILY SSF55008 2 67 8.64E-23 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 9.3E-22 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 Gene3D G3DSA:3.30.70.100 1 67 8.9E-23 T 29-03-2018 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 PRINTS PR00946 Mercury scavenger protein signature 41 55 6.9E-9 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 PRINTS PR00946 Mercury scavenger protein signature 26 41 6.9E-9 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 PRINTS PR00946 Mercury scavenger protein signature 55 67 6.9E-9 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 PRINTS PR00946 Mercury scavenger protein signature 10 26 6.9E-9 T 29-03-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 A616_RS12755 2880ef02c9624b1c2f1b7f78c55c00d2 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A616_RS11065 a176c1b65ab041fbcb2d918d17723e58 389 Pfam PF08245 Mur ligase middle domain 26 218 1.1E-38 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS11065 a176c1b65ab041fbcb2d918d17723e58 389 SUPERFAMILY SSF53623 21 237 2.09E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS11065 a176c1b65ab041fbcb2d918d17723e58 389 Gene3D G3DSA:3.90.190.20 238 389 8.1E-32 T 29-03-2018 A616_RS11065 a176c1b65ab041fbcb2d918d17723e58 389 Pfam PF02875 Mur ligase family, glutamate ligase domain 240 322 5.5E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS11065 a176c1b65ab041fbcb2d918d17723e58 389 SUPERFAMILY SSF53244 240 377 2.14E-27 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS11065 a176c1b65ab041fbcb2d918d17723e58 389 Gene3D G3DSA:3.40.1190.10 8 234 1.2E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 Gene3D G3DSA:3.40.50.1820 488 757 3.8E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 Gene3D G3DSA:2.140.10.30 20 485 2.1E-69 T 29-03-2018 A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 SUPERFAMILY SSF82171 102 482 3.27E-39 T 29-03-2018 A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 SUPERFAMILY SSF82171 32 75 3.27E-39 T 29-03-2018 A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 100 463 1.8E-60 T 29-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 SUPERFAMILY SSF53474 494 749 9.61E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28715 0ee6ed9d887a9981971422c4bb85a5aa 773 Pfam PF00326 Prolyl oligopeptidase family 558 749 9.5E-39 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A616_RS04020 1d38dc69f218238a8b64d3c39f610a66 490 Pfam PF01425 Amidase 24 468 1.0E-158 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS04020 1d38dc69f218238a8b64d3c39f610a66 490 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 479 93.414 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS04020 1d38dc69f218238a8b64d3c39f610a66 490 Gene3D G3DSA:3.90.1300.10 1 486 5.8E-172 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS04020 1d38dc69f218238a8b64d3c39f610a66 490 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 8.4E-196 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS04020 1d38dc69f218238a8b64d3c39f610a66 490 SUPERFAMILY SSF75304 3 485 5.23E-166 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS04020 1d38dc69f218238a8b64d3c39f610a66 490 ProSitePatterns PS00571 Amidases signature. 153 184 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Gene3D G3DSA:3.20.20.450 553 810 4.0E-105 T 29-03-2018 IPR001633 EAL domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SUPERFAMILY SSF141868 560 803 5.75E-93 T 29-03-2018 IPR001633 EAL domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SUPERFAMILY SSF55785 20 119 3.32E-25 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SUPERFAMILY SSF55785 279 377 2.09E-11 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Gene3D G3DSA:3.30.450.20 11 137 1.4E-28 T 29-03-2018 A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Pfam PF08448 PAS fold 279 375 1.7E-6 T 29-03-2018 IPR013656 PAS fold-4 A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SUPERFAMILY SSF55073 390 547 2.2E-52 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 383 543 3.4E-45 T 29-03-2018 IPR000160 GGDEF domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 PIRSF PIRSF005925 129 327 2.7E-7 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 PIRSF PIRSF005925 4 141 1.1E-7 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 PIRSF PIRSF005925 361 813 4.1E-140 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Gene3D G3DSA:3.40.50.10600 138 258 6.0E-30 T 29-03-2018 A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00267 374 545 3.6E-73 T 29-03-2018 IPR000160 GGDEF domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SUPERFAMILY SSF55785 148 247 3.14E-27 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00086 208 250 6.3E-8 T 29-03-2018 IPR001610 PAC motif A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00086 336 374 53.0 T 29-03-2018 IPR001610 PAC motif A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00086 80 122 8.3E-7 T 29-03-2018 IPR001610 PAC motif A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00052 555 798 9.8E-131 T 29-03-2018 IPR001633 EAL domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Gene3D G3DSA:3.30.70.270 383 552 2.5E-62 T 29-03-2018 A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Pfam PF00990 Diguanylate cyclase, GGDEF domain 385 541 1.4E-53 T 29-03-2018 IPR000160 GGDEF domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 277 380 2.1E-9 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 129 2.6E-16 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 257 1.8E-16 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Pfam PF13426 PAS domain 21 121 2.6E-14 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Pfam PF13426 PAS domain 148 249 1.6E-13 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Gene3D G3DSA:3.30.450.20 259 382 5.2E-16 T 29-03-2018 A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 Pfam PF00563 EAL domain 561 793 5.9E-76 T 29-03-2018 IPR001633 EAL domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00091 263 333 250.0 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00091 9 78 0.48 T 29-03-2018 IPR000014 PAS domain A616_RS12745 2c25ba74f3bac909ca1c7b12d33bf32a 815 SMART SM00091 134 206 0.33 T 29-03-2018 IPR000014 PAS domain A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 Pfam PF07687 Peptidase dimerisation domain 188 276 2.9E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 SUPERFAMILY SSF55031 186 292 4.84E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 PIRSF PIRSF005962 1 390 2.5E-133 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 Gene3D G3DSA:3.40.630.10 2 247 1.2E-45 T 29-03-2018 A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 Gene3D G3DSA:3.40.630.10 251 391 4.7E-25 T 29-03-2018 A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 376 1.3E-119 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 Pfam PF01546 Peptidase family M20/M25/M40 75 386 3.3E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 SUPERFAMILY SSF53187 6 199 3.89E-84 T 29-03-2018 A616_RS12130 c35ae601c1cdc6d56894dd02e2b4f899 391 SUPERFAMILY SSF53187 300 388 3.89E-84 T 29-03-2018 A616_RS15540 1dd385c4ddfd187e445d58c632a4c041 152 Pfam PF13452 N-terminal half of MaoC dehydratase 9 142 9.3E-35 T 29-03-2018 A616_RS15540 1dd385c4ddfd187e445d58c632a4c041 152 PIRSF PIRSF018072 1 152 2.5E-37 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 A616_RS15540 1dd385c4ddfd187e445d58c632a4c041 152 SUPERFAMILY SSF54637 9 151 2.15E-27 T 29-03-2018 IPR029069 HotDog domain A616_RS15540 1dd385c4ddfd187e445d58c632a4c041 152 Gene3D G3DSA:3.10.129.10 4 152 4.1E-30 T 29-03-2018 A616_RS14060 80b528badd23b317e5d8e948ec2e7a38 619 Pfam PF01432 Peptidase family M3 224 603 1.6E-75 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS14060 80b528badd23b317e5d8e948ec2e7a38 619 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 27 616 8.5E-211 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 A616_RS14060 80b528badd23b317e5d8e948ec2e7a38 619 SUPERFAMILY SSF55486 22 599 2.07E-130 T 29-03-2018 A616_RS14060 80b528badd23b317e5d8e948ec2e7a38 619 Pfam PF08439 Oligopeptidase F 134 203 8.9E-26 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A616_RS14060 80b528badd23b317e5d8e948ec2e7a38 619 Gene3D G3DSA:1.10.1370.10 102 617 4.2E-46 T 29-03-2018 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 SUPERFAMILY SSF88659 143 191 9.81E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 97 110 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 PRINTS PR00046 Major sigma-70 factor signature 121 129 8.5E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 PRINTS PR00046 Major sigma-70 factor signature 289 300 8.5E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 PRINTS PR00046 Major sigma-70 factor signature 253 265 8.5E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 PRINTS PR00046 Major sigma-70 factor signature 97 110 8.5E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 PRINTS PR00046 Major sigma-70 factor signature 274 289 8.5E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 68 303 3.4E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 SUPERFAMILY SSF88659 215 313 5.79E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 Gene3D G3DSA:1.10.601.10 10 141 2.6E-37 T 29-03-2018 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 Gene3D G3DSA:1.10.10.10 142 195 2.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 274 300 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 SUPERFAMILY SSF88946 32 141 1.09E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 Pfam PF04542 Sigma-70 region 2 74 140 5.3E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 Gene3D G3DSA:1.10.10.10 243 314 1.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01095 80cfb1bb151838e54e06beea701fb77e 314 Pfam PF04545 Sigma-70, region 4 249 301 5.3E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 SUPERFAMILY SSF52540 363 543 8.92E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 SUPERFAMILY SSF50447 772 867 2.1E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Gene3D G3DSA:2.40.30.10 551 672 5.3E-36 T 29-03-2018 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Gene3D G3DSA:3.30.56.50 3 45 7.5E-11 T 29-03-2018 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Gene3D G3DSA:3.30.56.50 296 337 1.8E-8 T 29-03-2018 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Gene3D G3DSA:3.40.50.10050 673 749 2.6E-28 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 288 868 8.0E-272 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Pfam PF00009 Elongation factor Tu GTP binding domain 375 530 1.5E-34 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Gene3D G3DSA:3.40.50.300 366 550 2.7E-40 T 29-03-2018 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 372 529 1.3E-38 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 SUPERFAMILY SSF52156 647 777 1.57E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 294 344 2.9E-14 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 49 2.9E-9 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 SUPERFAMILY SSF50447 542 625 1.79E-27 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 ProSitePatterns PS01176 Initiation factor 2 signature. 821 843 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Gene3D G3DSA:2.40.30.10 771 868 5.0E-29 T 29-03-2018 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 868 17.782 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A616_RS19800 42733f1bd41f30d56f324795a5d3aae3 868 Pfam PF11987 Translation-initiation factor 2 656 760 1.7E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A616_RS11340 5706c4b574cb379d7944bc1ae5e6087f 339 Gene3D G3DSA:3.40.50.1980 40 176 4.0E-31 T 29-03-2018 A616_RS11340 5706c4b574cb379d7944bc1ae5e6087f 339 Pfam PF01497 Periplasmic binding protein 73 312 6.9E-35 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS11340 5706c4b574cb379d7944bc1ae5e6087f 339 SUPERFAMILY SSF53807 60 339 3.92E-51 T 29-03-2018 A616_RS11340 5706c4b574cb379d7944bc1ae5e6087f 339 Gene3D G3DSA:3.40.50.1980 177 339 1.3E-40 T 29-03-2018 A616_RS20310 acf963e6c37995b4cc144ff65e3aee2a 322 SMART SM00382 47 260 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20310 acf963e6c37995b4cc144ff65e3aee2a 322 SUPERFAMILY SSF52540 33 249 6.88E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20310 acf963e6c37995b4cc144ff65e3aee2a 322 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS20310 acf963e6c37995b4cc144ff65e3aee2a 322 Pfam PF00005 ABC transporter 39 182 3.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS20310 acf963e6c37995b4cc144ff65e3aee2a 322 Gene3D G3DSA:3.40.50.300 1 267 2.0E-54 T 29-03-2018 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 PIRSF PIRSF001491 2 390 8.4E-165 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 Gene3D G3DSA:3.40.720.10 211 387 7.3E-18 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 Hamap MF_00740 Phosphopentomutase [deoB]. 3 387 54.801 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 Pfam PF01676 Metalloenzyme superfamily 5 378 4.1E-46 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 SUPERFAMILY SSF53649 217 390 1.83E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 SUPERFAMILY SSF53649 1 100 1.83E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 SUPERFAMILY SSF143856 100 216 2.35E-51 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 Gene3D G3DSA:3.30.70.1250 99 210 1.7E-56 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A616_RS13345 ac8f7ad3c43607fa1b1617edfff7de47 390 TIGRFAM TIGR01696 deoB: phosphopentomutase 5 385 4.8E-184 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A616_RS29140 a608bbf9f73621f72b4851cafb10d7cd 336 SUPERFAMILY SSF142338 13 320 1.19E-106 T 29-03-2018 A616_RS29140 a608bbf9f73621f72b4851cafb10d7cd 336 Hamap MF_00973 Gluconeogenesis factor. 12 326 36.108 T 29-03-2018 IPR010119 Gluconeogenesis factor A616_RS29140 a608bbf9f73621f72b4851cafb10d7cd 336 Gene3D G3DSA:3.40.50.10680 92 332 3.9E-61 T 29-03-2018 A616_RS29140 a608bbf9f73621f72b4851cafb10d7cd 336 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 16 323 6.5E-124 T 29-03-2018 IPR010119 Gluconeogenesis factor A616_RS29140 a608bbf9f73621f72b4851cafb10d7cd 336 Pfam PF01933 Uncharacterised protein family UPF0052 16 301 3.4E-107 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Gene3D G3DSA:2.60.40.1080 36 121 6.3E-18 T 29-03-2018 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Gene3D G3DSA:2.60.40.1080 286 370 2.7E-17 T 29-03-2018 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Gene3D G3DSA:2.60.40.1080 205 285 6.0E-16 T 29-03-2018 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Gene3D G3DSA:2.60.40.1080 122 204 1.4E-17 T 29-03-2018 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SMART SM00635 288 368 2.0E-9 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SMART SM00635 205 285 4.2E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SMART SM00635 39 119 4.3E-10 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SMART SM00635 122 202 7.9E-12 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Pfam PF02368 Bacterial Ig-like domain (group 2) 46 107 2.2E-9 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Pfam PF02368 Bacterial Ig-like domain (group 2) 213 276 7.3E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Pfam PF02368 Bacterial Ig-like domain (group 2) 294 361 1.7E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 Pfam PF02368 Bacterial Ig-like domain (group 2) 128 190 1.7E-7 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SUPERFAMILY SSF49373 120 205 1.8E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SUPERFAMILY SSF49373 202 281 2.35E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SUPERFAMILY SSF49373 287 369 2.98E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS04925 6ef943ddb6a0af6c2864e236d16531b4 370 SUPERFAMILY SSF49373 40 120 5.26E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Pfam PF03147 Ferredoxin-fold anticodon binding domain 713 806 4.3E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SUPERFAMILY SSF46955 410 481 4.58E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SMART SM00896 713 806 1.7E-44 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Pfam PF01588 Putative tRNA binding domain 46 152 1.3E-25 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Pfam PF03483 B3/4 domain 222 392 1.5E-62 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Gene3D G3DSA:3.50.40.10 202 403 2.7E-65 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SUPERFAMILY SSF55681 473 700 7.46E-52 T 29-03-2018 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SUPERFAMILY SSF56037 208 399 3.66E-65 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Gene3D G3DSA:3.30.56.10 409 481 2.4E-22 T 29-03-2018 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 800 45.242 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SMART SM00874 409 477 2.2E-26 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Pfam PF03484 tRNA synthetase B5 domain 412 477 4.5E-19 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Gene3D G3DSA:3.30.56.10 1 197 1.0E-51 T 29-03-2018 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Gene3D G3DSA:3.30.70.380 709 806 4.1E-28 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SMART SM00873 218 392 4.3E-78 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 806 6.4E-269 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 Gene3D G3DSA:3.30.930.10 495 700 2.5E-40 T 29-03-2018 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SUPERFAMILY SSF54991 709 806 1.11E-30 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A616_RS09585 ebac718b67f8595b544b2633cfc81299 807 SUPERFAMILY SSF50249 37 199 7.59E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 Gene3D G3DSA:1.10.1790.10 179 285 3.3E-29 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 Pfam PF00874 PRD domain 86 174 2.3E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 Pfam PF00874 PRD domain 192 280 1.3E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 SUPERFAMILY SSF63520 69 175 4.05E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 SMART SM01061 9 70 4.8E-19 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 SUPERFAMILY SSF50151 9 65 1.11E-12 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 Pfam PF03123 CAT RNA binding domain 9 67 9.3E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 Gene3D G3DSA:2.30.24.10 5 64 2.0E-22 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 Gene3D G3DSA:1.10.1790.10 65 178 3.8E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS00380 eec7de8bd929f4989acff8b076f6dc6c 285 SUPERFAMILY SSF63520 184 281 3.79E-27 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS26950 4ce0c94af7e8986c6adfd24b09fa534b 393 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 228 384 3.8E-23 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS26950 4ce0c94af7e8986c6adfd24b09fa534b 393 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 14 386 2.8E-64 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 Gene3D G3DSA:1.10.1740.10 1 92 5.5E-20 T 29-03-2018 A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 172 1.2E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 Pfam PF08281 Sigma-70, region 4 120 169 8.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 Pfam PF04542 Sigma-70 region 2 23 89 1.1E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 Gene3D G3DSA:1.10.10.10 93 176 2.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 SUPERFAMILY SSF88659 106 173 8.6E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02655 4250df6a966956efb4f03d54b4bff3af 184 SUPERFAMILY SSF88946 3 101 2.35E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 Pfam PF00571 CBS domain 288 338 3.6E-6 T 29-03-2018 IPR000644 CBS domain A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 Pfam PF00571 CBS domain 221 276 7.2E-4 T 29-03-2018 IPR000644 CBS domain A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 Gene3D G3DSA:3.30.465.10 346 430 7.1E-21 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 Gene3D G3DSA:3.10.580.10 199 345 9.0E-31 T 29-03-2018 A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 SMART SM01091 352 430 1.0E-20 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 Pfam PF01595 Domain of unknown function DUF21 11 204 2.8E-51 T 29-03-2018 IPR002550 Domain of unknown function DUF21 A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 SUPERFAMILY SSF56176 352 434 1.47E-19 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 Pfam PF03471 Transporter associated domain 353 428 1.3E-17 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS22340 666a43c119970cb8aa1a209633e2a339 439 SUPERFAMILY SSF54631 208 341 4.27E-30 T 29-03-2018 A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 SUPERFAMILY SSF49785 532 655 1.13E-38 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 Gene3D G3DSA:2.60.120.260 465 656 6.8E-30 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 SUPERFAMILY SSF55486 227 348 2.08E-5 T 29-03-2018 A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 154 433 1.6E-58 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 SUPERFAMILY SSF55486 312 354 2.42E-5 T 29-03-2018 A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 PIRSF PIRSF036597 5 548 9.9E-166 T 29-03-2018 IPR012045 Peptidase M6, unassigned InhA-related A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 PIRSF PIRSF036597 580 643 7.9E-5 T 29-03-2018 IPR012045 Peptidase M6, unassigned InhA-related A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 PIRSF PIRSF036597 540 586 0.014 T 29-03-2018 IPR012045 Peptidase M6, unassigned InhA-related A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 Gene3D G3DSA:3.40.390.10 157 373 7.3E-6 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A616_RS28435 de719fca5a591301936e8941a0b2e2f0 656 Pfam PF00754 F5/8 type C domain 534 651 2.5E-25 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 382 8.1E-103 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 Gene3D G3DSA:3.20.20.140 68 355 4.0E-108 T 29-03-2018 A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 Pfam PF01979 Amidohydrolase family 55 384 2.7E-26 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 SUPERFAMILY SSF51338 355 387 3.68E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 SUPERFAMILY SSF51338 7 57 3.68E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 Gene3D G3DSA:2.30.40.10 1 67 2.8E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 SUPERFAMILY SSF51556 58 355 3.89E-100 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS24630 75d944f82adcfc77d901b5d24893abc3 389 PIRSF PIRSF038994 3 388 1.4E-132 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A616_RS27495 02c2e874e5a731204864c6a920a9dbb2 251 SUPERFAMILY SSF48179 147 245 5.61E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS27495 02c2e874e5a731204864c6a920a9dbb2 251 Gene3D G3DSA:1.10.1040.10 147 248 1.7E-26 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS27495 02c2e874e5a731204864c6a920a9dbb2 251 Gene3D G3DSA:3.40.50.720 15 146 7.5E-13 T 29-03-2018 A616_RS27495 02c2e874e5a731204864c6a920a9dbb2 251 SUPERFAMILY SSF51735 25 145 5.15E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27495 02c2e874e5a731204864c6a920a9dbb2 251 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 31 144 2.5E-10 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS27495 02c2e874e5a731204864c6a920a9dbb2 251 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 148 243 7.5E-23 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Pfam PF01043 SecA preprotein cross-linking domain 231 339 6.8E-42 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SUPERFAMILY SSF52540 4 227 8.41E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SUPERFAMILY SSF52540 349 396 8.41E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.877 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SUPERFAMILY SSF81767 226 349 3.27E-46 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SUPERFAMILY SSF81886 572 789 7.46E-73 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Pfam PF07517 SecA DEAD-like domain 6 383 1.4E-131 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 497 2.6E-240 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SMART SM00958 227 339 6.7E-67 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Gene3D G3DSA:3.40.50.300 398 585 1.3E-54 T 29-03-2018 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 100 114 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 62 86 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 116 126 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 169 189 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 394 407 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 320 342 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 PRINTS PR00906 SecA protein signature 357 374 5.9E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 ProSitePatterns PS01312 SecA family signature. 481 496 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Pfam PF07516 SecA Wing and Scaffold domain 569 778 8.7E-66 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SUPERFAMILY SSF52540 398 570 6.86E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 SMART SM00957 5 383 8.5E-287 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Gene3D G3DSA:3.40.50.300 8 271 2.1E-56 T 29-03-2018 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Gene3D G3DSA:3.40.50.300 283 397 3.2E-9 T 29-03-2018 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Gene3D G3DSA:1.10.3060.10 586 693 3.0E-30 T 29-03-2018 A616_RS29400 9eb6b5d71bc19ba0c12705d1cee3e55e 839 Gene3D G3DSA:1.10.3060.10 694 790 9.0E-25 T 29-03-2018 A616_RS02905 a7e4868d46d5072522454157dfda160a 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 105 2.4E-26 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A616_RS02905 a7e4868d46d5072522454157dfda160a 108 SUPERFAMILY SSF52091 6 106 6.87E-23 T 29-03-2018 IPR002645 STAS domain A616_RS02905 a7e4868d46d5072522454157dfda160a 108 Gene3D G3DSA:3.30.750.24 11 106 2.4E-17 T 29-03-2018 IPR002645 STAS domain A616_RS02905 a7e4868d46d5072522454157dfda160a 108 Pfam PF01740 STAS domain 18 100 1.6E-15 T 29-03-2018 IPR002645 STAS domain A616_RS28205 448598671dafaac57a85463603e68a69 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 420 2.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28205 448598671dafaac57a85463603e68a69 423 Pfam PF07694 5TMR of 5TMR-LYT 26 186 1.0E-11 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A616_RS28205 448598671dafaac57a85463603e68a69 423 SMART SM00388 206 272 7.9E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28205 448598671dafaac57a85463603e68a69 423 SUPERFAMILY SSF55874 277 419 4.45E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28205 448598671dafaac57a85463603e68a69 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 210 268 2.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28205 448598671dafaac57a85463603e68a69 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28205 448598671dafaac57a85463603e68a69 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28205 448598671dafaac57a85463603e68a69 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28205 448598671dafaac57a85463603e68a69 423 SMART SM00387 314 422 3.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28205 448598671dafaac57a85463603e68a69 423 Gene3D G3DSA:1.10.287.130 196 268 6.4E-10 T 29-03-2018 A616_RS28205 448598671dafaac57a85463603e68a69 423 SUPERFAMILY SSF47384 198 268 3.34E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28205 448598671dafaac57a85463603e68a69 423 Gene3D G3DSA:3.30.565.10 273 423 4.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1820 1894 4.32E-12 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 615 697 1.5E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 872 958 1.2E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1907 1991 7.5E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 960 1043 3.9E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1730 1813 1.96E-10 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 359 445 3.8E-17 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1127 1209 1.1E-15 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1476 1557 1.5E-14 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 446 528 7.0E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1388 1475 3.6E-11 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 615 697 1.2E-12 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1208 1295 2.35E-12 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 1127 1210 9.81E-13 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1559 1642 2.35E-11 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 700 780 4.12E-12 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 785 866 3.2E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 359 439 1.5E-15 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1474 1554 1.1E-14 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1054 1122 4.1E-10 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1822 1894 8.4E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1561 1642 1.0E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1301 1382 3.1E-8 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1389 1463 9.3E-9 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1735 1815 7.3E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 872 954 3.3E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 531 610 1.4E-15 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1648 1728 1.8E-10 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 702 779 1.6E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1213 1295 8.5E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1127 1208 2.2E-15 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 2080 2162 5.1E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 445 525 3.9E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 1907 1988 1.9E-15 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 615 696 1.7E-14 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Pfam PF13620 Carboxypeptidase regulatory-like domain 961 1040 5.0E-14 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 955 1040 6.47E-10 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 1648 1732 5.1E-11 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 871 954 3.92E-10 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 531 611 9.02E-13 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1170 227 332 9.3E-11 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1042 1123 2.35E-11 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1648 1731 9.0E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1734 1817 5.7E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1560 1645 1.0E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 359 443 1.06E-15 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 1475 1555 1.44E-13 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1906 1988 8.04E-11 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1298 1385 1.3E-8 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 2076 2163 3.9E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1992 2075 1.5E-6 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1210 1297 2.8E-14 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 529 611 1.7E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 780 868 2.6E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 698 779 7.9E-13 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1044 1123 1.1E-12 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 Gene3D G3DSA:2.60.40.1120 1819 1895 1.3E-14 T 29-03-2018 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1300 1382 1.43E-8 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 1993 2070 1.04E-6 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 2074 2163 4.32E-12 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49452 439 525 2.55E-11 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 1389 1470 2.39E-10 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25120 924d3db64d5ffab0f2e0a1c32457f6bc 2184 SUPERFAMILY SSF49464 785 866 5.1E-12 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain A616_RS25870 ad833b128b4de72adfac71ef5b6e5034 391 Pfam PF02655 ATP-grasp domain 115 281 3.6E-10 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 A616_RS25870 ad833b128b4de72adfac71ef5b6e5034 391 SUPERFAMILY SSF56059 108 286 5.48E-22 T 29-03-2018 A616_RS25870 ad833b128b4de72adfac71ef5b6e5034 391 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272 279 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS25870 ad833b128b4de72adfac71ef5b6e5034 391 Gene3D G3DSA:3.30.470.20 118 296 8.6E-25 T 29-03-2018 A616_RS25870 ad833b128b4de72adfac71ef5b6e5034 391 Gene3D G3DSA:3.40.50.20 1 117 9.5E-14 T 29-03-2018 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 14 367 47.228 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 PIRSF PIRSF004762 4 367 6.9E-104 T 29-03-2018 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 SUPERFAMILY SSF102114 23 351 9.29E-43 T 29-03-2018 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 16 364 3.7E-136 T 29-03-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 59 364 5.8E-101 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 Pfam PF04055 Radical SAM superfamily 67 234 1.3E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS26335 8426269194484ea8272a2db1944d88f6 367 Gene3D G3DSA:3.20.20.70 6 366 2.0E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS26865 fb0a1e72b13e4881e88770d42a20ae05 394 Pfam PF07690 Major Facilitator Superfamily 11 242 3.7E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS26865 fb0a1e72b13e4881e88770d42a20ae05 394 SUPERFAMILY SSF103473 5 380 4.58E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS26865 fb0a1e72b13e4881e88770d42a20ae05 394 Gene3D G3DSA:1.20.1250.20 193 382 1.6E-27 T 29-03-2018 A616_RS26865 fb0a1e72b13e4881e88770d42a20ae05 394 Gene3D G3DSA:1.20.1250.20 4 192 2.2E-24 T 29-03-2018 A616_RS26865 fb0a1e72b13e4881e88770d42a20ae05 394 ProSitePatterns PS00216 Sugar transport proteins signature 1. 256 273 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF52777 216 487 2.0E-52 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 5342 5411 3.27E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 6710 7064 1.54E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 7094 7116 1.54E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 2314 2344 1.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 2213 2280 1.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 2322 2594 3.1E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00550 Phosphopantetheine attachment site 2214 2275 2.4E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00550 Phosphopantetheine attachment site 6597 6662 9.2E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00550 Phosphopantetheine attachment site 3716 3780 1.4E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00550 Phosphopantetheine attachment site 3827 3889 2.3E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00550 Phosphopantetheine attachment site 1024 1085 6.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00550 Phosphopantetheine attachment site 5344 5405 1.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 4370 4388 1.04E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 3958 4332 1.04E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 1127 1388 5.1E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.30.559.10 21 212 2.8E-23 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.50.980 491 652 3.9E-52 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4340 4441 8.9E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2712 2827 6.7E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1504 1623 1.3E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5856 5966 1.4E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 1014 1137 7.98E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF14765 Polyketide synthase dehydratase 2961 3248 3.4E-62 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF14765 Polyketide synthase dehydratase 4585 4877 8.4E-60 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF51735 5064 5310 1.38E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:1.10.1200.10 3820 3939 6.3E-12 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:1.10.1200.10 5342 5453 8.4E-13 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:1.10.1200.10 3709 3819 1.5E-9 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.50.720 3431 3698 3.5E-44 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.50.720 5062 5328 1.5E-50 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.50.720 1930 2187 5.2E-47 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF13193 AMP-binding enzyme C-terminal domain 916 993 7.7E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 5886 5905 5.01E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 5472 5848 5.01E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 ProSitePatterns PS00455 Putative AMP-binding domain signature. 647 658 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 3709 3783 1.1E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 3824 3895 1.44E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.50.980 653 817 5.9E-35 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF51735 6306 6555 1.59E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF51735 3433 3676 5.48E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF08659 KR domain 5069 5254 6.4E-62 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF08659 KR domain 1938 2123 2.2E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF08659 KR domain 6310 6505 9.1E-40 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF08659 KR domain 3438 3623 1.8E-55 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:1.10.1200.10 2206 2286 1.4E-9 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1383 1501 5.7E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6953 7067 8.4E-34 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5735 5852 4.7E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2591 2708 7.3E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4219 4336 2.2E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF51735 1934 2171 1.09E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00823 Phosphopantetheine attachment site 2209 2279 5.4E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00823 Phosphopantetheine attachment site 1020 1089 0.013 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00823 Phosphopantetheine attachment site 6595 6666 4.3E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00823 Phosphopantetheine attachment site 5340 5410 9.4E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00823 Phosphopantetheine attachment site 3713 3784 0.0014 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00823 Phosphopantetheine attachment site 3824 3894 2.5E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF56801 457 1033 2.22E-162 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:2.30.38.10 818 898 5.8E-27 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.10.129.10 2963 3091 1.0E-22 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.10.129.10 4587 4715 9.4E-18 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6308 6506 2.2E-34 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3438 3624 6.2E-53 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1938 2124 1.6E-50 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5069 5255 2.5E-58 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00825 Beta-ketoacyl synthase 1125 1554 8.9E-151 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00825 Beta-ketoacyl synthase 3959 4394 1.4E-202 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00825 Beta-ketoacyl synthase 6715 7119 2.8E-118 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00825 Beta-ketoacyl synthase 2332 2770 9.2E-194 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00825 Beta-ketoacyl synthase 5475 5910 3.9E-205 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 1530 1550 6.7E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 1120 1238 6.7E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 1271 1497 6.7E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 6595 6667 4.19E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF47336 6697 6728 4.19E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6858 6874 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM01294 6596 6662 2.4E-6 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.30.300.30 903 1023 1.7E-37 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:1.10.1200.10 6589 6675 1.7E-14 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 1391 1552 1.9E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 5742 5908 6.3E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 4226 4392 1.5E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 2598 2768 1.3E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 6960 7117 1.3E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1123 1375 2.0E-64 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5474 5727 3.8E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3958 4211 9.9E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6714 6945 4.5E-65 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2330 2583 1.0E-78 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 521 932 1.8E-136 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF51735 6109 6289 1.3E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3850 3865 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 6705 6957 8.0E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 3949 4223 1.9E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.47.10 5465 5739 2.1E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00826 4585 4752 1.7E-20 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SMART SM00826 2961 3128 3.0E-26 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF52777 36 208 2.0E-34 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00501 AMP-binding enzyme 500 908 5.8E-112 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1044 1059 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:1.10.1200.10 1024 1098 1.1E-17 T 29-03-2018 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 2327 2701 1.12E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 SUPERFAMILY SSF53901 2746 2765 1.12E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5366 5381 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Pfam PF00668 Condensation domain 35 480 6.4E-106 T 29-03-2018 IPR001242 Condensation domain A616_RS22040 926fa33d36555a116f27afdfd3465be2 7173 Gene3D G3DSA:3.40.50.720 6304 6588 7.8E-37 T 29-03-2018 A616_RS10360 3d038367604ef373705c06575de892f6 158 Pfam PF14526 Integron-associated effector binding protein 4 156 7.3E-21 T 29-03-2018 IPR029441 Integron-associated effector binding protein A616_RS10360 3d038367604ef373705c06575de892f6 158 SMART SM00871 1 158 8.4E-15 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS10360 3d038367604ef373705c06575de892f6 158 SUPERFAMILY SSF55136 1 158 1.27E-18 T 29-03-2018 A616_RS10360 3d038367604ef373705c06575de892f6 158 Gene3D G3DSA:3.20.80.10 1 158 5.8E-29 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS15310 6b85aef49311d7b1d64369fda5fca99e 452 SUPERFAMILY SSF53187 3 273 1.22E-25 T 29-03-2018 A616_RS15310 6b85aef49311d7b1d64369fda5fca99e 452 Pfam PF00246 Zinc carboxypeptidase 18 186 2.6E-10 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A616_RS15310 6b85aef49311d7b1d64369fda5fca99e 452 Gene3D G3DSA:3.40.630.10 2 309 7.5E-22 T 29-03-2018 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 500 7.9E-20 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 Pfam PF00682 HMGL-like 5 272 6.5E-89 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 SMART SM00917 347 501 5.5E-11 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 SUPERFAMILY SSF110921 401 499 3.14E-15 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 SUPERFAMILY SSF51569 1 291 2.75E-93 T 29-03-2018 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 498 2.7E-187 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS05750 03f2c21895b1859183ffc7e9dc6299e0 514 Gene3D G3DSA:3.20.20.70 1 331 4.6E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS15035 2735d0e3bc486ef98680c1044f784c27 96 Pfam PF00462 Glutaredoxin 7 63 1.9E-10 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A616_RS15035 2735d0e3bc486ef98680c1044f784c27 96 SUPERFAMILY SSF52833 6 63 4.56E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS15035 2735d0e3bc486ef98680c1044f784c27 96 Gene3D G3DSA:3.40.30.10 1 81 8.2E-11 T 29-03-2018 A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 SUPERFAMILY SSF88946 3 106 1.37E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 Pfam PF04542 Sigma-70 region 2 23 89 1.3E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 173 2.2E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 SUPERFAMILY SSF88659 107 174 2.43E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 Gene3D G3DSA:1.10.10.10 93 177 2.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 Gene3D G3DSA:1.10.1740.10 1 92 1.7E-24 T 29-03-2018 A616_RS03910 4aecea59d0229ae8b0afc21a46b9a7ca 185 Pfam PF08281 Sigma-70, region 4 118 170 4.0E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 Gene3D G3DSA:3.30.70.250 144 186 4.4E-20 T 29-03-2018 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 305 5.6E-47 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 SUPERFAMILY SSF55048 130 195 2.09E-15 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 Pfam PF00698 Acyl transferase domain 6 285 2.2E-42 T 29-03-2018 IPR014043 Acyl transferase A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 Gene3D G3DSA:3.40.366.10 187 312 8.2E-32 T 29-03-2018 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 2.6E-115 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 SUPERFAMILY SSF52151 192 309 1.91E-80 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 SUPERFAMILY SSF52151 4 123 1.91E-80 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 PIRSF PIRSF000446 1 312 1.4E-115 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A616_RS20290 18f1586df1a037a13dc9212de67d57a5 316 Gene3D G3DSA:3.40.366.10 3 143 8.7E-43 T 29-03-2018 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 Gene3D G3DSA:1.10.150.20 171 251 1.4E-14 T 29-03-2018 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 Gene3D G3DSA:3.30.70.270 112 170 1.5E-8 T 29-03-2018 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 Gene3D G3DSA:3.30.70.270 37 111 2.2E-16 T 29-03-2018 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 SUPERFAMILY SSF56672 2 241 8.36E-60 T 29-03-2018 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 Pfam PF11799 impB/mucB/samB family C-terminal domain 248 358 4.8E-12 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 Pfam PF00817 impB/mucB/samB family 3 150 8.9E-41 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 Gene3D G3DSA:3.30.1490.100 252 365 9.0E-14 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS20635 fc4dcadeb42b69bbd1a5cf2d282264d4 413 SUPERFAMILY SSF100879 248 351 9.61E-10 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS24725 6884ee13d2037246a79e0fc1370cbc50 205 Gene3D G3DSA:3.40.50.360 1 205 3.9E-43 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS24725 6884ee13d2037246a79e0fc1370cbc50 205 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 197 6.7E-48 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 A616_RS24725 6884ee13d2037246a79e0fc1370cbc50 205 Pfam PF03358 NADPH-dependent FMN reductase 12 148 7.1E-18 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A616_RS24725 6884ee13d2037246a79e0fc1370cbc50 205 SUPERFAMILY SSF52218 4 199 6.16E-48 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS05825 d6574c04f1b9910082f23c776707e61a 137 Gene3D G3DSA:3.40.630.30 74 130 2.8E-14 T 29-03-2018 A616_RS05825 d6574c04f1b9910082f23c776707e61a 137 Pfam PF13673 Acetyltransferase (GNAT) domain 35 126 1.7E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS05825 d6574c04f1b9910082f23c776707e61a 137 Gene3D G3DSA:3.40.630.30 1 73 4.7E-15 T 29-03-2018 A616_RS05825 d6574c04f1b9910082f23c776707e61a 137 PIRSF PIRSF037663 1 134 1.0E-11 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted A616_RS05825 d6574c04f1b9910082f23c776707e61a 137 SUPERFAMILY SSF55729 1 128 1.15E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 513 5.9E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 Gene3D G3DSA:1.10.287.950 75 308 8.7E-11 T 29-03-2018 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 26 1.5E-27 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 306 335 1.5E-27 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 460 489 1.5E-27 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 412 441 1.5E-27 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 410 1.5E-27 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 Pfam PF12729 Four helix bundle sensory module for signal transduction 2 158 3.2E-11 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 SUPERFAMILY SSF58104 224 258 1.44E-75 T 29-03-2018 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 SUPERFAMILY SSF58104 291 560 1.44E-75 T 29-03-2018 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 SMART SM00304 202 256 2.8E-16 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 Pfam PF00672 HAMP domain 202 253 4.6E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 SMART SM00283 285 560 4.5E-86 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 Gene3D G3DSA:1.10.287.950 480 552 2.7E-5 T 29-03-2018 A616_RS02495 c839723dcab9c30358a760b336a9d1c6 561 Gene3D G3DSA:1.10.287.950 309 479 7.0E-50 T 29-03-2018 A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 ProSitePatterns PS00042 Crp-type HTH domain signature. 174 197 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 SMART SM00100 8 127 9.2E-14 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 SMART SM00419 166 215 1.6E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 Gene3D G3DSA:1.10.10.10 137 224 4.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 172 188 2.4E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 188 203 2.4E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 Pfam PF00027 Cyclic nucleotide-binding domain 27 113 5.5E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 SUPERFAMILY SSF51206 8 142 1.44E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 SUPERFAMILY SSF46785 146 231 4.43E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 2.8E-16 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS26135 32c858f6ce2578b33443740acceaa5b9 235 Gene3D G3DSA:2.60.120.10 5 136 5.4E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS01145 7eed23e4e993032366333b662ee2fca0 283 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 60 73 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS01145 7eed23e4e993032366333b662ee2fca0 283 Pfam PF00809 Pterin binding enzyme 27 260 2.3E-83 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS01145 7eed23e4e993032366333b662ee2fca0 283 SUPERFAMILY SSF51717 13 277 1.7E-101 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS01145 7eed23e4e993032366333b662ee2fca0 283 Gene3D G3DSA:3.20.20.20 5 280 2.2E-109 T 29-03-2018 A616_RS01145 7eed23e4e993032366333b662ee2fca0 283 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 26 41 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A616_RS01145 7eed23e4e993032366333b662ee2fca0 283 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 26 275 3.2E-97 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A616_RS12800 1f74b3a5d0f39435144496c4b8ec3fba 290 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 266 282 - T 29-03-2018 IPR028871 Blue (type 1) copper protein, binding site A616_RS12800 1f74b3a5d0f39435144496c4b8ec3fba 290 Pfam PF13473 Cupredoxin-like domain 154 277 3.0E-9 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain A616_RS12800 1f74b3a5d0f39435144496c4b8ec3fba 290 SUPERFAMILY SSF49503 182 288 4.8E-19 T 29-03-2018 IPR008972 Cupredoxin A616_RS12800 1f74b3a5d0f39435144496c4b8ec3fba 290 Gene3D G3DSA:2.60.40.420 178 290 8.6E-17 T 29-03-2018 IPR008972 Cupredoxin A616_RS12800 1f74b3a5d0f39435144496c4b8ec3fba 290 ProSitePatterns PS00079 Multicopper oxidases signature 1. 266 286 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 Gene3D G3DSA:3.40.50.300 631 871 1.4E-53 T 29-03-2018 A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 Gene3D G3DSA:1.10.10.10 925 979 1.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 Pfam PF09397 Ftsk gamma domain 926 985 1.4E-23 T 29-03-2018 IPR018541 FtsK gamma domain A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 SMART SM00843 923 988 1.2E-31 T 29-03-2018 IPR018541 FtsK gamma domain A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 SUPERFAMILY SSF46785 924 989 2.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 Pfam PF01580 FtsK/SpoIIIE family 645 776 1.6E-46 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 Pfam PF01580 FtsK/SpoIIIE family 777 828 2.5E-14 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A616_RS23465 d36eedd83eac23f9075ca622142eb817 1000 SUPERFAMILY SSF52540 615 896 6.38E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27555 4c9db92bf0691c9e0c1c58ecd5065658 208 Gene3D G3DSA:1.20.120.80 19 203 2.1E-51 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27555 4c9db92bf0691c9e0c1c58ecd5065658 208 SUPERFAMILY SSF81452 20 201 1.11E-53 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27555 4c9db92bf0691c9e0c1c58ecd5065658 208 Pfam PF00510 Cytochrome c oxidase subunit III 26 201 2.2E-18 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08075 33b522f3f8ece17980209092f657475a 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 42.766 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A616_RS08075 33b522f3f8ece17980209092f657475a 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 3.5E-105 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A616_RS08075 33b522f3f8ece17980209092f657475a 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 4.7E-26 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A616_RS08075 33b522f3f8ece17980209092f657475a 276 Gene3D G3DSA:1.10.8.50 135 276 1.9E-46 T 29-03-2018 A616_RS08075 33b522f3f8ece17980209092f657475a 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A616_RS08075 33b522f3f8ece17980209092f657475a 276 SMART SM00898 2 118 6.7E-48 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A616_RS08075 33b522f3f8ece17980209092f657475a 276 SUPERFAMILY SSF81624 2 139 1.7E-42 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A616_RS08075 33b522f3f8ece17980209092f657475a 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 5.8E-34 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A616_RS08075 33b522f3f8ece17980209092f657475a 276 SUPERFAMILY SSF46946 135 227 5.89E-27 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A616_RS08075 33b522f3f8ece17980209092f657475a 276 Gene3D G3DSA:3.20.190.10 2 133 7.3E-41 T 29-03-2018 A616_RS08075 33b522f3f8ece17980209092f657475a 276 Pfam PF06827 Zinc finger found in FPG and IleRS 247 275 1.6E-7 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A616_RS08075 33b522f3f8ece17980209092f657475a 276 SUPERFAMILY SSF57716 222 274 4.75E-16 T 29-03-2018 A616_RS08075 33b522f3f8ece17980209092f657475a 276 SMART SM01232 134 226 3.7E-43 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 SUPERFAMILY SSF56014 393 535 6.41E-31 T 29-03-2018 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 PRINTS PR00397 Sirohaem Fe-binding site signature 393 411 2.3E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 PRINTS PR00397 Sirohaem Fe-binding site signature 437 455 2.3E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 SUPERFAMILY SSF55124 6 136 3.49E-33 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 SUPERFAMILY SSF55124 272 404 5.38E-22 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 396 532 1.1E-8 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 137 290 7.1E-36 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Gene3D G3DSA:3.30.413.10 392 538 2.1E-25 T 29-03-2018 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Gene3D G3DSA:3.90.480.10 235 377 4.5E-23 T 29-03-2018 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Gene3D G3DSA:3.90.480.10 66 224 1.4E-21 T 29-03-2018 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 314 376 5.8E-15 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 63 127 3.7E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS23500 dd6d7ce6d0a7486225ed339cdc10623c 538 SUPERFAMILY SSF56014 137 292 1.57E-41 T 29-03-2018 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 SUPERFAMILY SSF47413 2 60 1.38E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 TIGRFAM TIGR01481 ccpA: catabolite control protein A 2 332 2.9E-153 T 29-03-2018 IPR006377 Catabolite control protein A GO:0006355 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.4E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 Gene3D G3DSA:1.10.260.40 3 58 3.1E-26 T 29-03-2018 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 SMART SM00354 2 72 1.9E-40 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 Pfam PF13377 Periplasmic binding protein-like domain 169 331 2.6E-37 T 29-03-2018 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 8.2E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 8.2E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 Gene3D G3DSA:3.40.50.2300 59 167 4.9E-30 T 29-03-2018 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 Gene3D G3DSA:3.40.50.2300 168 334 4.5E-53 T 29-03-2018 A616_RS22980 db932981d49a5f86fbde5469ac4996d7 336 SUPERFAMILY SSF53822 62 333 8.7E-91 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 Gene3D G3DSA:1.20.1250.20 1 196 3.2E-33 T 29-03-2018 A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 Pfam PF07690 Major Facilitator Superfamily 13 406 3.4E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 SUPERFAMILY SSF103473 244 456 5.1E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 SUPERFAMILY SSF103473 3 192 5.1E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.2E-13 T 29-03-2018 A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.2E-13 T 29-03-2018 A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 1.2E-13 T 29-03-2018 A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.2E-13 T 29-03-2018 A616_RS01935 4ae130eaa11f2214d16df444f224c784 465 Gene3D G3DSA:1.20.1250.20 255 465 1.2E-28 T 29-03-2018 A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 SUPERFAMILY SSF48179 185 284 1.62E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 3.3E-65 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 Gene3D G3DSA:3.40.50.720 1 184 5.3E-59 T 29-03-2018 A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 SUPERFAMILY SSF51735 2 185 9.63E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 Gene3D G3DSA:1.10.1040.10 185 285 1.4E-28 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 PIRSF PIRSF000105 1 285 1.7E-90 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A616_RS27500 e88c0b937a8456b35be1c2e336ce468e 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 283 1.2E-29 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 Pfam PF04542 Sigma-70 region 2 22 86 3.0E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 SUPERFAMILY SSF88659 121 175 4.86E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 Pfam PF08281 Sigma-70, region 4 118 169 1.7E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 172 1.1E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 Gene3D G3DSA:1.10.1740.10 7 91 2.0E-21 T 29-03-2018 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 SUPERFAMILY SSF88946 13 102 2.43E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30180 82af8963cd747fa4cc2a4038535afb0d 179 Gene3D G3DSA:1.10.10.10 101 179 5.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 Pfam PF00664 ABC transporter transmembrane region 150 385 1.1E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 ProSitePatterns PS00211 ABC transporters family signature. 565 579 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 SUPERFAMILY SSF52540 419 663 4.67E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 Pfam PF00005 ABC transporter 444 593 1.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 SUPERFAMILY SSF90123 139 418 2.22E-70 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 SUPERFAMILY SSF90123 5 44 2.22E-70 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 Gene3D G3DSA:1.20.1560.10 2 413 2.3E-67 T 29-03-2018 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 Gene3D G3DSA:3.40.50.300 417 669 6.7E-71 T 29-03-2018 A616_RS04845 ef02e64f245d3740fb464141cafb9797 685 SMART SM00382 453 645 1.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 PIRSF PIRSF001413 3 405 3.0E-169 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 SUPERFAMILY SSF53686 12 398 1.18E-145 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 Gene3D G3DSA:3.40.50.1100 208 403 6.2E-38 T 29-03-2018 A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 387 3.4E-45 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 Gene3D G3DSA:3.40.50.1100 75 207 3.7E-36 T 29-03-2018 A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 Gene3D G3DSA:3.40.50.1100 18 74 2.3E-6 T 29-03-2018 A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 90 104 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 16 399 1.1E-192 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS13825 d15caa702c4cd1059488e4732fe16ef5 406 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 11 400 53.06 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.50.720 2702 2961 1.3E-44 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF47336 413 481 5.63E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF47336 1468 1543 4.06E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53901 2015 2034 4.29E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53901 1601 1970 4.29E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1497 1512 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3109 3124 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3210 3456 3.6E-80 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1601 1852 9.7E-88 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 547 781 1.3E-80 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53901 944 962 3.43E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53901 547 899 3.43E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53335 137 330 1.64E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.47.10 3201 3467 1.4E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00825 Beta-ketoacyl synthase 549 968 8.2E-185 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00825 Beta-ketoacyl synthase 1602 2039 7.6E-204 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00825 Beta-ketoacyl synthase 3211 3643 8.1E-169 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3370 3386 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF47336 3080 3156 5.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53901 3206 3574 2.73E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF53901 3619 3638 2.73E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF14765 Polyketide synthase dehydratase 1152 1440 4.0E-56 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF14765 Polyketide synthase dehydratase 2226 2511 1.9E-64 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.47.10 1603 1865 3.6E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3878 3893 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00550 Phosphopantetheine attachment site 3857 3919 8.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00550 Phosphopantetheine attachment site 2976 3040 1.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00550 Phosphopantetheine attachment site 1473 1536 9.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00550 Phosphopantetheine attachment site 414 476 2.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF00550 Phosphopantetheine attachment site 3085 3149 8.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.47.10 540 793 2.8E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:1.10.1200.10 3848 3949 4.8E-12 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM01294 3853 3919 5.9E-5 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM01294 3084 3149 9.7E-4 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM01294 1472 1537 0.0015 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF08242 Methyltransferase domain 171 275 2.0E-12 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF51735 2705 2948 1.73E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF47336 2970 3047 7.07E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF08659 KR domain 2710 2895 1.3E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 ProSitePatterns PS00012 Phosphopantetheine attachment site. 436 451 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3464 3580 1.3E-36 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 789 905 1.7E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1860 1976 2.1E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.10.129.10 2227 2356 8.3E-21 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.10.129.10 1155 1281 1.6E-18 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:1.10.1200.10 3068 3157 2.2E-13 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.47.10 1867 2037 5.4E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.47.10 3471 3641 1.3E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.47.10 797 966 2.3E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:3.40.50.150 70 340 6.2E-18 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 694 710 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2710 2896 8.7E-48 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SUPERFAMILY SSF47336 3847 3923 3.66E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 910 1025 8.4E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3585 3705 9.6E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1981 2104 1.8E-10 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:1.10.1200.10 1466 1587 1.3E-12 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:1.10.1200.10 2966 3067 6.4E-13 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 Gene3D G3DSA:1.10.1200.10 374 483 5.0E-11 T 29-03-2018 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00826 2226 2393 1.5E-24 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00826 1152 1323 1.4E-14 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00823 Phosphopantetheine attachment site 3852 3923 0.0068 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00823 Phosphopantetheine attachment site 2973 3044 3.7E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00823 Phosphopantetheine attachment site 410 480 8.1E-8 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00823 Phosphopantetheine attachment site 3083 3153 3.9E-14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22045 2e13dba8dd84e478168a323a180d6373 3975 SMART SM00823 Phosphopantetheine attachment site 1471 1541 3.9E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 SUPERFAMILY SSF88659 100 167 7.1E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 Gene3D G3DSA:1.10.10.10 112 180 6.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 SUPERFAMILY SSF88946 11 84 2.04E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 36 67 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 Pfam PF04542 Sigma-70 region 2 14 80 3.8E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 Pfam PF08281 Sigma-70, region 4 111 163 3.5E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 166 2.2E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28220 bed39ea77b88aaaecbb7890feb989db8 181 Gene3D G3DSA:1.10.1740.10 6 111 7.0E-22 T 29-03-2018 A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 Gene3D G3DSA:1.10.10.10 94 188 9.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 185 4.7E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 Gene3D G3DSA:1.10.1740.10 15 93 1.0E-14 T 29-03-2018 A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 Pfam PF04542 Sigma-70 region 2 32 99 2.6E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 SUPERFAMILY SSF88946 25 114 1.73E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 SUPERFAMILY SSF88659 115 187 2.62E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25425 a0abb4b59dd4723b10d7642432a5bdc4 194 Pfam PF08281 Sigma-70, region 4 129 181 2.4E-10 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28065 5abfa31522be91d058bdbc07dda3461b 144 Gene3D G3DSA:3.10.450.40 18 140 4.0E-8 T 29-03-2018 A616_RS28065 5abfa31522be91d058bdbc07dda3461b 144 Pfam PF10934 Protein of unknown function (DUF2634) 24 126 2.1E-18 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SUPERFAMILY SSF52440 1 127 8.34E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SUPERFAMILY SSF48108 394 546 5.36E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 829 836 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:3.40.50.20 4 117 1.7E-38 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:3.30.1490.20 647 736 2.4E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1056 13.17 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SUPERFAMILY SSF52335 928 1050 5.63E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:3.40.50.1380 927 1059 2.8E-35 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:3.30.470.20 737 926 2.4E-38 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SMART SM01209 671 835 0.0032 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 863 1.5E-33 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 6.0E-83 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:3.40.50.20 531 646 2.9E-59 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Pfam PF02142 MGS-like domain 949 1030 2.2E-16 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SMART SM00851 948 1035 1.8E-21 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1046 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1062 13.619 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 701 715 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 539 5.1E-43 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SMART SM01096 420 539 4.1E-66 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.2E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:3.30.470.20 120 401 7.3E-67 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SUPERFAMILY SSF56059 665 926 1.08E-99 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 Gene3D G3DSA:1.10.1030.10 402 530 2.0E-51 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SUPERFAMILY SSF56059 128 399 2.83E-110 T 29-03-2018 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21000 5cf6b8ceeee96ba1b0ada1a369851864 1070 SUPERFAMILY SSF52440 548 667 3.45E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.740 685 825 3.4E-17 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.740 544 679 3.8E-15 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.740 267 404 1.4E-13 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.740 127 266 4.1E-18 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.740 405 543 1.3E-15 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Pfam PF05737 Collagen binding domain 276 386 4.0E-12 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Pfam PF05737 Collagen binding domain 131 253 5.2E-25 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Pfam PF05737 Collagen binding domain 548 670 1.3E-24 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Pfam PF05737 Collagen binding domain 689 809 1.8E-13 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Pfam PF05737 Collagen binding domain 419 525 1.8E-8 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49478 845 905 1.1E-5 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.1280 1 124 3.6E-21 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Pfam PF00746 LPXTG cell wall anchor motif 1382 1418 3.5E-6 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1385 1418 1.2E-6 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49478 1043 1112 3.18E-8 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49478 947 1015 2.94E-5 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49401 5 117 4.8E-14 T 29-03-2018 IPR008966 Adhesion domain A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49401 269 403 2.29E-19 T 29-03-2018 IPR008966 Adhesion domain A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.10 1034 1128 2.5E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49478 1139 1207 3.84E-6 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.810 926 1033 9.7E-26 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.810 832 925 1.1E-19 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 Gene3D G3DSA:2.60.40.810 1129 1232 1.1E-21 T 29-03-2018 A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49401 547 670 6.05E-19 T 29-03-2018 IPR008966 Adhesion domain A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49401 686 812 1.62E-21 T 29-03-2018 IPR008966 Adhesion domain A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49401 133 255 2.98E-22 T 29-03-2018 IPR008966 Adhesion domain A616_RS31300 5f292ef94eef48b831841fda5376ce8b 1419 SUPERFAMILY SSF49401 414 531 2.16E-15 T 29-03-2018 IPR008966 Adhesion domain A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 Gene3D G3DSA:3.30.110.10 83 175 1.8E-35 T 29-03-2018 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 80 4.4E-34 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 Gene3D G3DSA:3.10.20.80 6 82 3.0E-35 T 29-03-2018 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 SUPERFAMILY SSF54364 9 82 1.7E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 SUPERFAMILY SSF55200 86 174 3.27E-33 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 4 174 30.933 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 173 7.8E-72 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS09430 1bcf2f29a011922e35bda4c0b5c758d4 175 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 172 1.4E-37 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A616_RS26035 1d750839b47aa95c18eab72860a2b356 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 293 1.1E-89 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS26035 1d750839b47aa95c18eab72860a2b356 311 Gene3D G3DSA:3.30.70.1350 214 295 2.8E-9 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A616_RS26035 1d750839b47aa95c18eab72860a2b356 311 Gene3D G3DSA:1.20.1510.10 17 213 9.7E-59 T 29-03-2018 A616_RS26035 1d750839b47aa95c18eab72860a2b356 311 SUPERFAMILY SSF160240 221 292 6.02E-7 T 29-03-2018 A616_RS26035 1d750839b47aa95c18eab72860a2b356 311 SUPERFAMILY SSF161111 15 216 3.4E-57 T 29-03-2018 A616_RS26035 1d750839b47aa95c18eab72860a2b356 311 Pfam PF01545 Cation efflux family 22 215 5.5E-48 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 SUPERFAMILY SSF47384 237 315 2.16E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 5.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 316 3.0E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 Gene3D G3DSA:1.10.287.130 244 315 3.4E-19 T 29-03-2018 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 SMART SM00388 254 320 1.2E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 SUPERFAMILY SSF55874 309 477 2.36E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 SMART SM00304 200 253 6.5E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 476 5.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 Gene3D G3DSA:3.30.565.10 326 483 4.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 SMART SM00387 366 477 9.7E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07435 b3e2b8dc350f5ffad703ba67a0c75901 484 SUPERFAMILY SSF158472 200 251 2.62E-6 T 29-03-2018 A616_RS19565 3faa26bfb75ebc03abd3a09f7d886689 366 Gene3D G3DSA:3.30.470.20 194 329 6.6E-15 T 29-03-2018 A616_RS19565 3faa26bfb75ebc03abd3a09f7d886689 366 Gene3D G3DSA:3.30.1490.20 129 193 3.9E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS19565 3faa26bfb75ebc03abd3a09f7d886689 366 Pfam PF14398 YheC/D like ATP-grasp 99 348 1.2E-72 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS19565 3faa26bfb75ebc03abd3a09f7d886689 366 SUPERFAMILY SSF56059 127 320 2.43E-16 T 29-03-2018 A616_RS03380 c176f48c0b1b8d29d2f400376ff17ed5 244 Gene3D G3DSA:2.40.320.10 10 194 1.5E-15 T 29-03-2018 A616_RS03380 c176f48c0b1b8d29d2f400376ff17ed5 244 Pfam PF09359 VTC domain 17 233 2.7E-21 T 29-03-2018 IPR018966 VTC domain A616_RS21225 c266b546206ba6d6f98ca723a251e046 232 PIRSF PIRSF004848 1 232 1.4E-69 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A616_RS21225 c266b546206ba6d6f98ca723a251e046 232 Pfam PF01168 Alanine racemase, N-terminal domain 12 229 1.0E-18 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS21225 c266b546206ba6d6f98ca723a251e046 232 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 79 93 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A616_RS21225 c266b546206ba6d6f98ca723a251e046 232 Gene3D G3DSA:3.20.20.10 1 232 1.3E-56 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS21225 c266b546206ba6d6f98ca723a251e046 232 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 11 229 2.5E-56 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A616_RS21225 c266b546206ba6d6f98ca723a251e046 232 SUPERFAMILY SSF51419 8 228 1.16E-70 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 SUPERFAMILY SSF118116 498 689 8.63E-57 T 29-03-2018 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 SMART SM00853 502 647 4.7E-48 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 SMART SM01340 209 327 6.8E-52 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 Pfam PF08676 MutL C terminal dimerisation domain 503 645 4.6E-41 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 SUPERFAMILY SSF55874 3 214 3.01E-55 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 Gene3D G3DSA:3.30.565.10 2 203 7.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 SUPERFAMILY SSF54211 190 327 2.39E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 Gene3D G3DSA:3.30.230.10 214 326 3.5E-27 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 305 8.8E-99 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 124 1.4E-12 T 29-03-2018 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 687 27.172 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site A616_RS19515 33ac5ad9006f54da3281fa352e11de01 691 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 326 1.5E-34 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SUPERFAMILY SSF54814 199 277 2.88E-31 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Pfam PF00575 S1 RNA binding domain 134 194 8.8E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Gene3D G3DSA:2.40.50.140 136 197 8.3E-14 T 29-03-2018 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 358 30.159 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Pfam PF13184 NusA-like KH domain 229 297 2.7E-29 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SUPERFAMILY SSF54814 278 341 6.54E-16 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SUPERFAMILY SSF50249 132 198 7.92E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SMART SM00316 133 199 9.1E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Gene3D G3DSA:3.30.1480.10 1 129 3.1E-47 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SMART SM00322 300 355 0.83 T 29-03-2018 IPR004087 K Homology domain GO:0003676 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SMART SM00322 229 292 0.39 T 29-03-2018 IPR004087 K Homology domain GO:0003676 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 SUPERFAMILY SSF69705 1 126 5.62E-41 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 342 1.5E-128 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Pfam PF08529 NusA N-terminal domain 4 123 1.8E-42 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Gene3D G3DSA:3.30.300.20 273 341 2.8E-17 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS19815 8558c19627d5f016aea5eb907409bbe0 363 Gene3D G3DSA:3.30.300.20 198 272 1.5E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS03415 ff3aacacee89a6bc46aadabe251282a5 385 SUPERFAMILY SSF52172 4 126 2.56E-11 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03415 ff3aacacee89a6bc46aadabe251282a5 385 Gene3D G3DSA:3.40.50.300 138 382 1.8E-35 T 29-03-2018 A616_RS03415 ff3aacacee89a6bc46aadabe251282a5 385 Gene3D G3DSA:3.40.50.2300 1 135 3.5E-9 T 29-03-2018 A616_RS03415 ff3aacacee89a6bc46aadabe251282a5 385 SUPERFAMILY SSF52540 141 383 4.96E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03415 ff3aacacee89a6bc46aadabe251282a5 385 Pfam PF13614 AAA domain 142 287 1.3E-13 T 29-03-2018 IPR025669 AAA domain A616_RS20655 b649e0fdae36f02a86f6ec1b5570c90e 120 SUPERFAMILY SSF54593 10 118 2.55E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS20655 b649e0fdae36f02a86f6ec1b5570c90e 120 Gene3D G3DSA:3.10.180.10 1 119 8.8E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS20655 b649e0fdae36f02a86f6ec1b5570c90e 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 116 5.6E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 SUPERFAMILY SSF52540 340 583 3.46E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 SUPERFAMILY SSF46689 552 644 6.05E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Pfam PF00158 Sigma-54 interaction domain 340 507 5.3E-61 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 552 561 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Gene3D G3DSA:1.10.10.60 579 645 5.7E-16 T 29-03-2018 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 364 377 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Pfam PF01590 GAF domain 112 199 3.0E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Gene3D G3DSA:1.10.8.60 514 578 1.1E-20 T 29-03-2018 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 427 442 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 625 645 1.8E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 608 625 1.8E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Pfam PF02954 Bacterial regulatory protein, Fis family 606 642 6.7E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 SMART SM00382 360 504 1.8E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Gene3D G3DSA:3.30.450.40 83 224 3.1E-4 T 29-03-2018 IPR029016 GAF domain-like A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 SUPERFAMILY SSF55781 93 207 2.2E-5 T 29-03-2018 IPR029016 GAF domain-like A616_RS09105 3af417b640337e7a762e5147b2cd4ed9 645 Gene3D G3DSA:3.40.50.300 333 512 7.1E-25 T 29-03-2018 A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 Pfam PF07690 Major Facilitator Superfamily 16 407 6.1E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 Gene3D G3DSA:1.20.1250.20 2 198 2.1E-31 T 29-03-2018 A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 SUPERFAMILY SSF103473 4 194 3.92E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 SUPERFAMILY SSF103473 464 497 3.92E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 SUPERFAMILY SSF103473 246 416 3.92E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 PRINTS PR01035 Tetracycline resistance protein signature 12 28 3.8E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 PRINTS PR01035 Tetracycline resistance protein signature 136 158 3.8E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 PRINTS PR01035 Tetracycline resistance protein signature 301 321 3.8E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS18080 f0b0af2d3b1579b49fc52d9ad4d047e9 503 Gene3D G3DSA:1.20.1250.20 250 503 4.8E-24 T 29-03-2018 A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 Gene3D G3DSA:1.10.10.10 149 218 1.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 Pfam PF13545 Crp-like helix-turn-helix domain 153 215 1.4E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 SUPERFAMILY SSF51206 11 147 7.07E-21 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 200 5.6E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 169 185 5.6E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 Gene3D G3DSA:2.60.120.10 4 148 1.7E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS04880 a1af25ceb559f8bd600b4d274abcabf1 219 SUPERFAMILY SSF46785 151 216 4.32E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 6.2E-118 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 SUPERFAMILY SSF52540 120 320 1.06E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 Gene3D G3DSA:3.40.50.300 117 322 4.1E-44 T 29-03-2018 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 SMART SM00963 22 103 2.4E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 SMART SM00962 120 321 1.9E-126 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 1.8E-13 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.661 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 Gene3D G3DSA:1.20.120.140 1 116 1.9E-19 T 29-03-2018 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 2.8E-83 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 SUPERFAMILY SSF47364 18 96 4.06E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20260 21f7ddb80d6aa56229fef49813da1b44 335 SMART SM00382 119 310 3.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 9 327 2.4E-103 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 Gene3D G3DSA:3.40.47.10 168 328 9.1E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 SUPERFAMILY SSF53901 9 329 2.81E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 8 329 63.68 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 191 1.1E-29 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 Gene3D G3DSA:3.40.47.10 3 167 1.2E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS10465 04b5bc0212cb590bc1336857afd5a04b 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 329 8.4E-30 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS29950 723f5a52875c7b893508c325700573fa 636 Gene3D G3DSA:3.40.50.1980 485 636 2.2E-30 T 29-03-2018 A616_RS29950 723f5a52875c7b893508c325700573fa 636 SUPERFAMILY SSF53807 401 635 1.06E-48 T 29-03-2018 A616_RS29950 723f5a52875c7b893508c325700573fa 636 Gene3D G3DSA:3.40.50.1980 362 484 1.7E-17 T 29-03-2018 A616_RS29950 723f5a52875c7b893508c325700573fa 636 SUPERFAMILY SSF46689 174 224 1.66E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS29950 723f5a52875c7b893508c325700573fa 636 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 227 269 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS29950 723f5a52875c7b893508c325700573fa 636 Pfam PF12833 Helix-turn-helix domain 196 274 4.1E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS29950 723f5a52875c7b893508c325700573fa 636 Gene3D G3DSA:1.10.10.60 241 286 1.7E-13 T 29-03-2018 A616_RS29950 723f5a52875c7b893508c325700573fa 636 Pfam PF01497 Periplasmic binding protein 411 610 7.9E-25 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS29950 723f5a52875c7b893508c325700573fa 636 Gene3D G3DSA:3.90.1240.10 134 240 2.2E-22 T 29-03-2018 A616_RS29950 723f5a52875c7b893508c325700573fa 636 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 257 273 8.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS29950 723f5a52875c7b893508c325700573fa 636 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 242 257 8.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS29950 723f5a52875c7b893508c325700573fa 636 SMART SM00342 190 273 1.9E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS29950 723f5a52875c7b893508c325700573fa 636 SUPERFAMILY SSF46689 226 276 4.39E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 ProSitePatterns PS01117 MarR-type HTH domain signature. 46 80 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 Pfam PF01047 MarR family 14 71 4.2E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 SUPERFAMILY SSF46785 4 122 4.41E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 SMART SM00347 7 107 2.7E-28 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 31 47 1.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 63 1.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 1.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 117 1.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS03620 848b4e55cfbf1c7fd049d01da6065056 127 Gene3D G3DSA:1.10.10.10 1 127 1.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28000 cafafb0564a66616e66ea4d752b1e3c4 362 Gene3D G3DSA:1.25.40.10 180 280 5.3E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28000 cafafb0564a66616e66ea4d752b1e3c4 362 Gene3D G3DSA:3.90.550.10 3 164 7.3E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28000 cafafb0564a66616e66ea4d752b1e3c4 362 Gene3D G3DSA:1.25.40.10 281 360 6.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28000 cafafb0564a66616e66ea4d752b1e3c4 362 SUPERFAMILY SSF48452 192 345 8.72E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28000 cafafb0564a66616e66ea4d752b1e3c4 362 SUPERFAMILY SSF53448 3 145 1.53E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28000 cafafb0564a66616e66ea4d752b1e3c4 362 Pfam PF00535 Glycosyl transferase family 2 5 98 3.6E-15 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 1.2E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 SMART SM01134 75 240 3.1E-60 T 29-03-2018 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 Gene3D G3DSA:3.40.50.1360 68 246 7.1E-37 T 29-03-2018 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 4.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 4.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 SUPERFAMILY SSF100950 77 239 3.24E-29 T 29-03-2018 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 Gene3D G3DSA:1.10.10.10 4 67 6.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 Pfam PF00455 DeoR C terminal sensor domain 77 239 3.5E-46 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 SUPERFAMILY SSF46785 6 70 3.07E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A616_RS00275 e16a3adde136b635c0a0c3074a05e15f 266 SMART SM00420 8 60 2.0E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Gene3D G3DSA:1.10.730.10 579 806 3.2E-63 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 SUPERFAMILY SSF50677 202 393 3.35E-63 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 833 0.0 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 917 20.955 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Pfam PF08264 Anticodon-binding domain of tRNA 677 833 1.1E-30 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Gene3D G3DSA:3.30.2320.20 807 884 1.4E-21 T 29-03-2018 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 SUPERFAMILY SSF52374 393 640 2.3E-151 T 29-03-2018 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 SUPERFAMILY SSF52374 1 201 2.3E-151 T 29-03-2018 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Gene3D G3DSA:3.90.740.10 204 490 5.3E-104 T 29-03-2018 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 633 6.4E-222 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 Gene3D G3DSA:3.40.50.620 41 175 5.2E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 SUPERFAMILY SSF47323 644 917 1.12E-73 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 3.4E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.4E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 3.4E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 3.4E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS21200 46769b1c5d1da1e269989eddca3019a9 925 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 3.4E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS29725 0f902d3499babe95a0b19b975f114603 354 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 230 7.4E-12 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS29725 0f902d3499babe95a0b19b975f114603 354 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 120 4.5E-32 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS29725 0f902d3499babe95a0b19b975f114603 354 Gene3D G3DSA:3.30.360.10 135 347 2.1E-46 T 29-03-2018 A616_RS29725 0f902d3499babe95a0b19b975f114603 354 SUPERFAMILY SSF55347 127 265 6.21E-34 T 29-03-2018 A616_RS29725 0f902d3499babe95a0b19b975f114603 354 Gene3D G3DSA:3.40.50.720 1 134 4.7E-41 T 29-03-2018 A616_RS29725 0f902d3499babe95a0b19b975f114603 354 SUPERFAMILY SSF51735 2 155 2.26E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30920 09effffb718054b44216d17b75bb2a3a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 90 115 4.4E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS30920 09effffb718054b44216d17b75bb2a3a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 4.4E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS30920 09effffb718054b44216d17b75bb2a3a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 4.4E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS30920 09effffb718054b44216d17b75bb2a3a 424 PIRSF PIRSF006066 1 424 4.3E-161 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 A616_RS30920 09effffb718054b44216d17b75bb2a3a 424 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 2.6E-137 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 A616_RS30920 09effffb718054b44216d17b75bb2a3a 424 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 415 1.5E-124 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A616_RS08575 2529e6948d8ff5a8e2b15245e221708e 312 Pfam PF01497 Periplasmic binding protein 62 280 1.4E-19 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS08575 2529e6948d8ff5a8e2b15245e221708e 312 Gene3D G3DSA:3.40.50.1980 151 310 9.4E-22 T 29-03-2018 A616_RS08575 2529e6948d8ff5a8e2b15245e221708e 312 SUPERFAMILY SSF53807 40 303 5.49E-38 T 29-03-2018 A616_RS08575 2529e6948d8ff5a8e2b15245e221708e 312 Gene3D G3DSA:3.40.50.1980 33 150 3.8E-14 T 29-03-2018 A616_RS32195 00a5e73cc511b95783796c77549b0ce2 207 SUPERFAMILY SSF51735 1 205 1.37E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS32195 00a5e73cc511b95783796c77549b0ce2 207 Pfam PF13460 NAD(P)H-binding 7 194 3.7E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS32195 00a5e73cc511b95783796c77549b0ce2 207 Gene3D G3DSA:3.40.50.720 2 203 1.8E-25 T 29-03-2018 A616_RS09680 10c1ff4b1026e03f3133fe8b40ff8650 365 Gene3D G3DSA:3.40.50.2000 179 346 7.5E-9 T 29-03-2018 A616_RS09680 10c1ff4b1026e03f3133fe8b40ff8650 365 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 313 3.4E-87 T 29-03-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB A616_RS09680 10c1ff4b1026e03f3133fe8b40ff8650 365 Pfam PF04230 Polysaccharide pyruvyl transferase 14 297 2.1E-47 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 Pfam PF00239 Resolvase, N terminal domain 4 144 1.2E-33 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 SUPERFAMILY SSF53041 2 145 1.96E-29 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 Pfam PF07508 Recombinase 168 284 1.6E-16 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 Gene3D G3DSA:1.20.5.40 116 143 1.2E-5 T 29-03-2018 A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 Pfam PF13408 Recombinase zinc beta ribbon domain 298 358 8.7E-10 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 Gene3D G3DSA:3.40.50.1390 1 115 8.5E-27 T 29-03-2018 A616_RS10970 68be6a7addd51ed12be507a7cbf98df1 499 SMART SM00857 2 145 6.6E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS00185 efe57bd48c49e2fdbbbd9f468da796fb 372 SUPERFAMILY SSF109604 150 315 2.6E-30 T 29-03-2018 A616_RS00185 efe57bd48c49e2fdbbbd9f468da796fb 372 SMART SM00471 151 287 9.0E-6 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS00185 efe57bd48c49e2fdbbbd9f468da796fb 372 Pfam PF13487 HD domain 206 268 1.5E-13 T 29-03-2018 A616_RS00185 efe57bd48c49e2fdbbbd9f468da796fb 372 Gene3D G3DSA:1.10.3210.10 2 323 5.3E-41 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 Gene3D G3DSA:3.90.640.10 192 249 3.6E-31 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 Gene3D G3DSA:3.30.420.40 158 191 4.8E-4 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 2.1E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 2.1E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 2.1E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 2.1E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 2.1E-59 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 SMART SM00268 6 344 0.0078 T 29-03-2018 IPR004000 Actin family A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 Gene3D G3DSA:3.30.420.40 4 157 9.7E-39 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 SUPERFAMILY SSF53067 6 143 1.46E-39 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 Pfam PF06723 MreB/Mbl protein 7 332 5.1E-152 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 Gene3D G3DSA:3.30.420.40 250 314 3.2E-10 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 SUPERFAMILY SSF53067 147 329 8.04E-51 T 29-03-2018 A616_RS10495 40b9a7e10b5c7bb77aecbb235d9286bb 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 333 4.0E-160 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 Pfam PF00005 ABC transporter 358 507 2.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 SUPERFAMILY SSF90123 13 325 3.66E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 SMART SM00382 367 559 3.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 SUPERFAMILY SSF52540 335 577 9.63E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 Pfam PF00664 ABC transporter transmembrane region 35 292 1.2E-35 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 Gene3D G3DSA:1.20.1560.10 4 328 2.4E-53 T 29-03-2018 A616_RS15680 2c973f6b4ab27485d9fb5d9d3811a687 599 Gene3D G3DSA:3.40.50.300 329 583 6.3E-78 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 SUPERFAMILY SSF47336 562 635 6.41E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Gene3D G3DSA:3.30.300.30 458 572 8.2E-36 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 545 9.9E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Gene3D G3DSA:2.30.38.10 374 453 2.9E-21 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Pfam PF00501 AMP-binding enzyme 45 463 5.1E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Gene3D G3DSA:3.30.559.10 644 834 2.8E-35 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 PIRSF PIRSF001617 4 431 9.7E-43 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 PIRSF PIRSF001617 510 668 3.4E-14 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 PIRSF PIRSF001617 830 1085 7.7E-6 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 PIRSF PIRSF001617 428 513 2.9E-15 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 SUPERFAMILY SSF56801 9 583 9.03E-159 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Gene3D G3DSA:3.40.50.980 36 207 1.8E-49 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Pfam PF00668 Condensation domain 653 1077 2.4E-106 T 29-03-2018 IPR001242 Condensation domain A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 SUPERFAMILY SSF52777 659 821 1.11E-40 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 66 487 1.9E-122 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Gene3D G3DSA:3.40.50.980 208 371 1.1E-40 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 SUPERFAMILY SSF52777 828 1074 1.28E-51 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Gene3D G3DSA:1.10.1200.10 573 643 2.5E-21 T 29-03-2018 A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 PRINTS PR00154 AMP-binding signature 197 208 3.5E-5 T 29-03-2018 IPR020459 AMP-binding A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 PRINTS PR00154 AMP-binding signature 209 217 3.5E-5 T 29-03-2018 IPR020459 AMP-binding A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 Pfam PF00550 Phosphopantetheine attachment site 571 634 3.2E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18525 720ec0b34c28445d76862bec51acff84 1096 SMART SM00823 Phosphopantetheine attachment site 570 639 5.7E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS09985 30b38c06aa5abb936dca951bbf085ef4 252 SUPERFAMILY SSF46785 1 92 6.82E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09985 30b38c06aa5abb936dca951bbf085ef4 252 Pfam PF11495 Archaeal transcriptional regulator TrmB 102 222 5.8E-5 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal A616_RS09985 30b38c06aa5abb936dca951bbf085ef4 252 Gene3D G3DSA:1.10.10.10 1 128 9.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09985 30b38c06aa5abb936dca951bbf085ef4 252 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 70 7.4E-18 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal A616_RS29085 7c24498388906ce04fd7e45169806a02 336 Gene3D G3DSA:3.40.50.1980 39 172 3.5E-28 T 29-03-2018 A616_RS29085 7c24498388906ce04fd7e45169806a02 336 Gene3D G3DSA:3.40.50.1980 173 335 1.0E-27 T 29-03-2018 A616_RS29085 7c24498388906ce04fd7e45169806a02 336 SUPERFAMILY SSF53807 53 330 1.7E-60 T 29-03-2018 A616_RS29085 7c24498388906ce04fd7e45169806a02 336 Pfam PF01497 Periplasmic binding protein 71 309 3.5E-26 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 SUPERFAMILY SSF52540 1 250 9.86E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 Gene3D G3DSA:3.40.50.300 1 317 1.0E-81 T 29-03-2018 A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 SMART SM00382 30 229 6.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 Pfam PF00005 ABC transporter 21 179 6.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 315 8.7E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14640 ee2b7fab9906e521fe7cfaf57b8d52a7 317 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 295 8.2E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS05385 a1460bfc0082e0460d835e120164ab45 108 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 107 22.823 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A616_RS05385 a1460bfc0082e0460d835e120164ab45 108 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 2 107 5.5E-48 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 A616_RS05385 a1460bfc0082e0460d835e120164ab45 108 SUPERFAMILY SSF103481 7 107 2.35E-11 T 29-03-2018 A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 Gene3D G3DSA:3.90.1150.10 2 162 2.2E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 Pfam PF00202 Aminotransferase class-III 17 436 2.0E-106 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 PIRSF PIRSF000521 17 439 6.1E-42 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 Gene3D G3DSA:3.90.1150.10 175 256 0.034 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 SUPERFAMILY SSF53383 15 436 2.45E-121 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS11810 1ef7963081c252b6dc8d17dc67013276 450 Gene3D G3DSA:3.90.1150.10 257 440 7.0E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS13950 d30387d281c5b25c983b8a0c38e0051f 287 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 8 269 44.966 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A616_RS13950 d30387d281c5b25c983b8a0c38e0051f 287 SUPERFAMILY SSF51621 8 269 5.1E-110 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS13950 d30387d281c5b25c983b8a0c38e0051f 287 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 9 270 3.3E-111 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A616_RS13950 d30387d281c5b25c983b8a0c38e0051f 287 Pfam PF02548 Ketopantoate hydroxymethyltransferase 8 264 3.5E-118 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A616_RS13950 d30387d281c5b25c983b8a0c38e0051f 287 Gene3D G3DSA:3.20.20.60 1 269 5.9E-88 T 29-03-2018 A616_RS13950 d30387d281c5b25c983b8a0c38e0051f 287 PIRSF PIRSF000388 1 272 1.6E-114 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 Pfam PF00137 ATP synthase subunit C 8 71 7.3E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 PRINTS PR00124 ATP synthase C subunit signature 30 45 5.1E-14 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 PRINTS PR00124 ATP synthase C subunit signature 47 72 5.1E-14 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 PRINTS PR00124 ATP synthase C subunit signature 9 28 5.1E-14 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 72 14.099 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 ProSitePatterns PS00605 ATP synthase c subunit signature. 37 58 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 SUPERFAMILY SSF81333 6 73 6.93E-17 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 Gene3D G3DSA:1.20.20.10 3 72 7.7E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A616_RS29925 c1ec51846ae39893e7d8c9ebc3f10d92 76 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 17 72 6.2E-20 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A616_RS07690 abe47beb446c92322862b27cc205ea50 331 SUPERFAMILY SSF81345 7 328 6.54E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS07690 abe47beb446c92322862b27cc205ea50 331 Gene3D G3DSA:1.10.3470.10 5 330 2.6E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS07690 abe47beb446c92322862b27cc205ea50 331 Pfam PF01032 FecCD transport family 20 328 2.5E-93 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 SUPERFAMILY SSF53901 4 206 2.66E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 Gene3D G3DSA:3.40.47.10 7 195 2.2E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 Gene3D G3DSA:3.40.47.10 196 358 4.3E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 221 356 9.3E-18 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 PIRSF PIRSF000451 1 358 1.5E-119 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 SUPERFAMILY SSF53901 214 356 5.35E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20445 9da98db31ed39e0dd15000770eb50d70 358 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 8 205 1.2E-24 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 Hamap MF_00268 Protein RecA [recA]. 4 328 52.755 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 Gene3D G3DSA:3.40.50.300 25 267 6.4E-45 T 29-03-2018 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 SUPERFAMILY SSF54752 267 324 1.57E-20 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 9.0E-172 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 ProSitePatterns PS00321 recA signature. 212 220 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 Pfam PF00154 recA bacterial DNA recombination protein 7 267 3.3E-144 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 SMART SM00382 56 227 1.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 SUPERFAMILY SSF52540 6 266 6.09E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 Gene3D G3DSA:3.30.250.10 268 325 2.7E-23 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 PRINTS PR00142 RecA protein signature 92 121 6.2E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 PRINTS PR00142 RecA protein signature 242 271 6.2E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 PRINTS PR00142 RecA protein signature 126 155 6.2E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 PRINTS PR00142 RecA protein signature 209 237 6.2E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 PRINTS PR00142 RecA protein signature 164 193 6.2E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS19620 3e759612ef5bf67f3c9b3fa4b490f3dc 352 PRINTS PR00142 RecA protein signature 296 313 6.2E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A616_RS05530 b81bfd94522e89b405c8bf68b9a3295c 266 PIRSF PIRSF005902 3 266 1.5E-77 T 29-03-2018 IPR001130 TatD family GO:0016788 A616_RS05530 b81bfd94522e89b405c8bf68b9a3295c 266 Gene3D G3DSA:3.20.20.140 6 266 2.9E-86 T 29-03-2018 A616_RS05530 b81bfd94522e89b405c8bf68b9a3295c 266 SUPERFAMILY SSF51556 8 265 5.55E-84 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS05530 b81bfd94522e89b405c8bf68b9a3295c 266 Pfam PF01026 TatD related DNase 9 265 2.6E-68 T 29-03-2018 IPR001130 TatD family GO:0016788 A616_RS05530 b81bfd94522e89b405c8bf68b9a3295c 266 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 197 213 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A616_RS05530 b81bfd94522e89b405c8bf68b9a3295c 266 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 8 265 2.1E-63 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A616_RS22590 6fa3c6f8e4c13e618c57c9620eeece31 322 Pfam PF06725 3D domain 261 321 1.8E-17 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A616_RS22590 6fa3c6f8e4c13e618c57c9620eeece31 322 Gene3D G3DSA:2.40.40.10 22 321 7.6E-29 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A616_RS22590 6fa3c6f8e4c13e618c57c9620eeece31 322 Pfam PF00395 S-layer homology domain 32 71 1.1E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS22590 6fa3c6f8e4c13e618c57c9620eeece31 322 Pfam PF00395 S-layer homology domain 183 207 1.5E-6 T 29-03-2018 IPR001119 S-layer homology domain A616_RS22590 6fa3c6f8e4c13e618c57c9620eeece31 322 Pfam PF00395 S-layer homology domain 90 136 1.1E-8 T 29-03-2018 IPR001119 S-layer homology domain A616_RS22590 6fa3c6f8e4c13e618c57c9620eeece31 322 SUPERFAMILY SSF50685 258 309 1.15E-7 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A616_RS10280 ec1ad00f7f30bdb9ba29c8c84bb67000 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 6 195 7.8E-58 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 A616_RS10280 ec1ad00f7f30bdb9ba29c8c84bb67000 197 Gene3D G3DSA:3.90.950.10 1 197 1.2E-77 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A616_RS10280 ec1ad00f7f30bdb9ba29c8c84bb67000 197 SUPERFAMILY SSF52972 4 196 2.88E-67 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A616_RS10280 ec1ad00f7f30bdb9ba29c8c84bb67000 197 Pfam PF01725 Ham1 family 7 194 7.5E-57 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 A616_RS10280 ec1ad00f7f30bdb9ba29c8c84bb67000 197 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 5 197 46.241 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 SUPERFAMILY SSF46689 257 305 1.61E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 Pfam PF12833 Helix-turn-helix domain 226 305 1.4E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 272 287 5.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 287 303 5.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 Gene3D G3DSA:2.60.120.10 27 262 3.4E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 Gene3D G3DSA:1.10.10.60 263 308 8.3E-11 T 29-03-2018 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 257 299 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS15010 108fda0f49a9e9b4423c53790aa1152e 308 SMART SM00342 220 303 1.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 Gene3D G3DSA:3.40.47.10 1 264 1.0E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 Pfam PF00108 Thiolase, N-terminal domain 4 261 9.9E-99 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 SUPERFAMILY SSF53901 3 269 8.18E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 Pfam PF02803 Thiolase, C-terminal domain 270 390 8.1E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 Gene3D G3DSA:3.40.47.10 265 389 1.9E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 PIRSF PIRSF000429 1 392 2.6E-121 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 389 9.7E-141 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 83 101 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS30170 c1f8d27c12507ffb743bb184c95766a3 392 SUPERFAMILY SSF53901 270 390 1.6E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 Pfam PF00072 Response regulator receiver domain 5 113 8.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 SUPERFAMILY SSF52172 2 127 7.54E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 SUPERFAMILY SSF46894 126 230 5.95E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 Gene3D G3DSA:3.40.50.2300 1 128 1.7E-34 T 29-03-2018 A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 SMART SM00862 153 229 8.3E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 SMART SM00448 3 113 1.1E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 Gene3D G3DSA:1.10.10.10 129 231 1.9E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04695 fbfb76db7c9c9f88d3939391d6d36580 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 2.4E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS19185 817d210ce354a961988d3366b8933246 212 Gene3D G3DSA:2.30.110.10 6 187 1.0E-35 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS19185 817d210ce354a961988d3366b8933246 212 Pfam PF01613 Flavin reductase like domain 12 160 2.6E-9 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 A616_RS19185 817d210ce354a961988d3366b8933246 212 SUPERFAMILY SSF50475 7 197 1.71E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 Gene3D G3DSA:3.40.630.10 9 377 1.4E-48 T 29-03-2018 A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 PIRSF PIRSF037238 2 377 6.4E-124 T 29-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 Pfam PF01546 Peptidase family M20/M25/M40 79 373 1.0E-23 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 Pfam PF07687 Peptidase dimerisation domain 180 271 1.1E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 SUPERFAMILY SSF55031 183 274 5.38E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 SUPERFAMILY SSF53187 3 192 7.65E-51 T 29-03-2018 A616_RS20735 b3e7b0dc2c9c97de72f230930a3464d1 377 SUPERFAMILY SSF53187 302 376 7.65E-51 T 29-03-2018 A616_RS14395 e0e69a61c1e7d4a33f9e3b864b6a49fa 348 SUPERFAMILY SSF53901 18 344 7.03E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS14395 e0e69a61c1e7d4a33f9e3b864b6a49fa 348 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 198 1.0E-14 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS14395 e0e69a61c1e7d4a33f9e3b864b6a49fa 348 Gene3D G3DSA:3.40.47.10 195 344 2.2E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS14395 e0e69a61c1e7d4a33f9e3b864b6a49fa 348 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 255 343 1.3E-19 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS14395 e0e69a61c1e7d4a33f9e3b864b6a49fa 348 Gene3D G3DSA:3.40.47.10 12 194 3.3E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 SUPERFAMILY SSF53850 85 287 8.69E-38 T 29-03-2018 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 Pfam PF03466 LysR substrate binding domain 83 287 2.9E-37 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 Gene3D G3DSA:3.40.190.10 169 257 5.6E-20 T 29-03-2018 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 Gene3D G3DSA:3.40.190.10 83 168 4.6E-13 T 29-03-2018 A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 SUPERFAMILY SSF46785 1 105 3.08E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 Gene3D G3DSA:1.10.10.10 1 82 1.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13210 4e30c83124e142aa2b67c9443844c3f5 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 6.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 SUPERFAMILY SSF52172 1 160 7.83E-34 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 SUPERFAMILY SSF46894 136 213 1.33E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 Gene3D G3DSA:1.10.10.10 136 212 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 Pfam PF00072 Response regulator receiver domain 6 115 8.4E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 207 2.2E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 SMART SM00421 150 207 1.8E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 Gene3D G3DSA:3.40.50.2300 3 135 5.4E-37 T 29-03-2018 A616_RS11995 8f48777b7ca186da81b139e2667f9f3b 215 SMART SM00448 4 117 1.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS28290 5a5984dc80f27ffac0471653ad458462 190 PIRSF PIRSF000709 1 177 5.0E-5 T 29-03-2018 A616_RS28290 5a5984dc80f27ffac0471653ad458462 190 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 178 7.0E-28 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS28290 5a5984dc80f27ffac0471653ad458462 190 Gene3D G3DSA:3.40.50.1240 1 188 4.3E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS28290 5a5984dc80f27ffac0471653ad458462 190 SUPERFAMILY SSF53254 1 182 4.71E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS28290 5a5984dc80f27ffac0471653ad458462 190 SMART SM00855 4 150 5.5E-4 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 96 110 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 SUPERFAMILY SSF55174 1 53 6.56E-14 T 29-03-2018 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 217 3.3E-47 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 Gene3D G3DSA:3.10.290.10 1 58 3.8E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 Pfam PF00849 RNA pseudouridylate synthase 61 187 3.0E-15 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 Gene3D G3DSA:3.30.70.1560 138 204 6.1E-27 T 29-03-2018 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 Pfam PF01479 S4 domain 1 46 7.7E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 Gene3D G3DSA:3.30.70.580 59 137 3.6E-16 T 29-03-2018 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 SMART SM00363 1 66 3.0E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS04895 b645f59792619a8957cbb4ac55b89d01 228 SUPERFAMILY SSF55120 59 221 2.37E-39 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS21820 8b3dd25c9d4421038d931fa38da63146 315 Pfam PF00753 Metallo-beta-lactamase superfamily 30 187 6.4E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS21820 8b3dd25c9d4421038d931fa38da63146 315 SUPERFAMILY SSF56281 9 278 8.65E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS21820 8b3dd25c9d4421038d931fa38da63146 315 SMART SM00849 26 230 2.8E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS21820 8b3dd25c9d4421038d931fa38da63146 315 Gene3D G3DSA:3.60.15.10 1 288 8.9E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 Gene3D G3DSA:3.40.50.620 1 192 1.4E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 Gene3D G3DSA:3.40.50.1220 193 318 9.7E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 Pfam PF01012 Electron transfer flavoprotein domain 4 174 5.7E-42 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 PIRSF PIRSF000089 1 318 3.6E-110 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 SUPERFAMILY SSF52402 2 189 1.95E-49 T 29-03-2018 A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 194 277 4.4E-35 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 SMART SM00893 4 186 8.8E-44 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS09720 2e31e6ad1b17c6939421624f16b0d7b4 319 SUPERFAMILY SSF52467 194 313 2.58E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS16330 e97eeea8667a61f699bc081871d021ee 229 Pfam PF14025 Protein of unknown function (DUF4241) 36 216 9.0E-52 T 29-03-2018 IPR025335 Protein of unknown function DUF4241 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 226 9.9E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 SMART SM00421 170 227 1.3E-27 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 Gene3D G3DSA:1.10.10.10 133 235 3.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 SUPERFAMILY SSF52172 8 139 3.27E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 8.3E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 8.3E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 8.3E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 Pfam PF00072 Response regulator receiver domain 10 122 9.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 SUPERFAMILY SSF46894 162 233 8.84E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 Gene3D G3DSA:3.40.50.2300 7 132 8.9E-32 T 29-03-2018 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 SMART SM00448 8 121 7.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS29610 2f54770d92b3b220503e4e20ab436ecb 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 187 214 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 Gene3D G3DSA:3.40.50.2300 181 307 4.0E-36 T 29-03-2018 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 Gene3D G3DSA:3.40.50.2300 308 376 1.3E-10 T 29-03-2018 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 6.1E-9 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 298 6.1E-9 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 74 90 6.1E-9 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 114 124 6.1E-9 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 Pfam PF13458 Periplasmic binding protein 53 385 5.7E-66 T 29-03-2018 IPR028081 Leucine-binding protein domain A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 SUPERFAMILY SSF53822 53 394 2.74E-85 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS09735 291ba3069aeb32e922e834abc2668e0c 395 Gene3D G3DSA:3.40.50.2300 51 180 4.7E-20 T 29-03-2018 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 Pfam PF00347 Ribosomal protein L6 11 82 1.2E-21 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 Pfam PF00347 Ribosomal protein L6 90 164 4.1E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 PIRSF PIRSF002162 1 177 3.0E-48 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 SUPERFAMILY SSF56053 1 82 5.6E-27 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 SUPERFAMILY SSF56053 83 177 1.04E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.5E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.5E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.5E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.847 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 Gene3D G3DSA:3.90.930.12 83 178 8.4E-39 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 Gene3D G3DSA:3.90.930.12 2 82 2.7E-31 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.1E-75 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS01475 003d0157f248bcdd5a917bfc3ec6f659 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 316 8.8E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 Pfam PF00672 HAMP domain 191 239 6.9E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 Gene3D G3DSA:3.30.565.10 322 484 3.4E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 SMART SM00387 365 478 2.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 SMART SM00388 251 318 1.5E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 SUPERFAMILY SSF158472 191 241 3.27E-11 T 29-03-2018 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 SMART SM00304 191 243 4.9E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 476 3.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 SUPERFAMILY SSF55874 307 475 3.41E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 4.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 4.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 4.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 4.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 Gene3D G3DSA:1.10.287.130 243 314 5.6E-14 T 29-03-2018 A616_RS25885 969e1ed175d0dd952d60297c58eeac2a 485 SUPERFAMILY SSF47384 242 319 7.46E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31775 3792c422c5d241c9945a325c9bd8ffcd 319 SUPERFAMILY SSF161098 70 297 6.67E-65 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31775 3792c422c5d241c9945a325c9bd8ffcd 319 Gene3D G3DSA:1.10.3720.10 76 307 3.0E-48 T 29-03-2018 A616_RS31775 3792c422c5d241c9945a325c9bd8ffcd 319 Gene3D G3DSA:1.20.58.370 9 60 8.2E-8 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS31775 3792c422c5d241c9945a325c9bd8ffcd 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 307 4.2E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 Pfam PF04545 Sigma-70, region 4 128 176 1.4E-10 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 Pfam PF04542 Sigma-70 region 2 25 91 3.4E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 SUPERFAMILY SSF88946 20 104 8.63E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 Gene3D G3DSA:1.10.1740.10 17 93 1.4E-17 T 29-03-2018 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 177 2.3E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 SUPERFAMILY SSF88659 105 180 4.3E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18900 0e0c3ec99053c526ad67d65174287825 184 Gene3D G3DSA:1.10.10.10 101 184 3.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 Gene3D G3DSA:3.40.250.10 1 118 4.1E-22 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 SMART SM00450 12 115 3.0E-14 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 SUPERFAMILY SSF52821 3 116 1.31E-21 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 Gene3D G3DSA:3.60.15.10 123 378 2.4E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 Pfam PF00753 Metallo-beta-lactamase superfamily 136 275 3.1E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 SMART SM00849 136 300 5.5E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 Pfam PF00581 Rhodanese-like domain 12 111 2.7E-13 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00440 8eb314b6e1018dd82a87041e7204dbcb 383 SUPERFAMILY SSF56281 130 356 5.55E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS26050 c6b1ad0a750137e04ad18c140cf99d58 320 Pfam PF00583 Acetyltransferase (GNAT) family 191 306 1.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS26050 c6b1ad0a750137e04ad18c140cf99d58 320 Pfam PF00583 Acetyltransferase (GNAT) family 15 119 1.4E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS26050 c6b1ad0a750137e04ad18c140cf99d58 320 SUPERFAMILY SSF55729 175 315 2.06E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS26050 c6b1ad0a750137e04ad18c140cf99d58 320 SUPERFAMILY SSF55729 3 123 2.06E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS26050 c6b1ad0a750137e04ad18c140cf99d58 320 Gene3D G3DSA:3.40.630.30 2 167 9.9E-16 T 29-03-2018 A616_RS26050 c6b1ad0a750137e04ad18c140cf99d58 320 Gene3D G3DSA:3.40.630.30 168 318 1.5E-22 T 29-03-2018 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 340 4.3E-154 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 Pfam PF02779 Transketolase, pyrimidine binding domain 355 526 1.0E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 Gene3D G3DSA:3.40.50.970 1 363 4.2E-113 T 29-03-2018 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 SMART SM00861 356 527 3.9E-70 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 SUPERFAMILY SSF52518 343 529 3.21E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 SUPERFAMILY SSF52922 537 668 2.88E-41 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 Pfam PF02780 Transketolase, C-terminal domain 552 658 1.7E-7 T 29-03-2018 IPR033248 Transketolase, C-terminal domain A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 667 5.6E-295 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 Gene3D G3DSA:3.40.50.920 545 666 1.2E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 Gene3D G3DSA:3.40.50.970 364 544 1.0E-45 T 29-03-2018 A616_RS23700 6931259d7f7e817ba79f8b1644c50750 668 SUPERFAMILY SSF52518 5 327 1.35E-118 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 Pfam PF00072 Response regulator receiver domain 5 112 2.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 Gene3D G3DSA:1.10.10.10 124 219 1.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 Gene3D G3DSA:3.40.50.2300 2 123 2.1E-31 T 29-03-2018 A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 SMART SM00448 3 112 9.6E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 SMART SM00862 145 217 4.3E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 SUPERFAMILY SSF52172 3 176 2.57E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23975 98bc4c408f0e87ea309dd33403581e50 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 2.9E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 SUPERFAMILY SSF48179 169 293 6.69E-40 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 Gene3D G3DSA:3.40.50.720 2 177 1.7E-31 T 29-03-2018 A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 290 4.1E-37 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 Gene3D G3DSA:1.10.1040.10 178 294 2.1E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 SUPERFAMILY SSF51735 10 168 3.36E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 PIRSF PIRSF000103 2 294 1.6E-68 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A616_RS25480 cd87b8f9ff58743a056de1e61c6bdd83 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 166 1.1E-49 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A616_RS30105 435e6df2f3fa5adbb1b9da8579446342 124 SMART SM00448 7 118 7.7E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30105 435e6df2f3fa5adbb1b9da8579446342 124 SUPERFAMILY SSF52172 6 122 5.27E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS30105 435e6df2f3fa5adbb1b9da8579446342 124 Gene3D G3DSA:3.40.50.2300 2 123 3.0E-37 T 29-03-2018 A616_RS30105 435e6df2f3fa5adbb1b9da8579446342 124 Pfam PF00072 Response regulator receiver domain 9 118 1.9E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS15260 92e483587585a789f37de08ed1305c85 433 Gene3D G3DSA:2.40.50.100 1 81 3.1E-18 T 29-03-2018 A616_RS15260 92e483587585a789f37de08ed1305c85 433 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A616_RS15260 92e483587585a789f37de08ed1305c85 433 Pfam PF00364 Biotin-requiring enzyme 3 75 1.4E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS15260 92e483587585a789f37de08ed1305c85 433 Gene3D G3DSA:3.30.559.10 184 429 8.7E-91 T 29-03-2018 A616_RS15260 92e483587585a789f37de08ed1305c85 433 SUPERFAMILY SSF52777 194 429 3.38E-88 T 29-03-2018 A616_RS15260 92e483587585a789f37de08ed1305c85 433 SUPERFAMILY SSF51230 2 92 5.37E-25 T 29-03-2018 IPR011053 Single hybrid motif A616_RS15260 92e483587585a789f37de08ed1305c85 433 Gene3D G3DSA:4.10.320.10 103 164 6.9E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS15260 92e483587585a789f37de08ed1305c85 433 SUPERFAMILY SSF47005 105 150 9.02E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS15260 92e483587585a789f37de08ed1305c85 433 Pfam PF02817 e3 binding domain 112 145 6.8E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS15260 92e483587585a789f37de08ed1305c85 433 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 201 429 9.9E-89 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS12055 e48b8ee2be1359b19b13d796e2ee53df 94 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 92 7.1E-22 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A616_RS12055 e48b8ee2be1359b19b13d796e2ee53df 94 Gene3D G3DSA:3.30.1360.20 2 94 2.8E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A616_RS12055 e48b8ee2be1359b19b13d796e2ee53df 94 SUPERFAMILY SSF55248 2 93 2.62E-22 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 A616_RS30930 64282dfd84bdf602cf1f517e876e7330 351 SUPERFAMILY SSF53850 178 292 1.01E-5 T 29-03-2018 A616_RS30930 64282dfd84bdf602cf1f517e876e7330 351 SUPERFAMILY SSF53850 75 139 1.01E-5 T 29-03-2018 A616_RS30930 64282dfd84bdf602cf1f517e876e7330 351 Gene3D G3DSA:3.40.190.10 1 321 1.9E-9 T 29-03-2018 A616_RS30930 64282dfd84bdf602cf1f517e876e7330 351 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 56 311 2.6E-80 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A616_RS30930 64282dfd84bdf602cf1f517e876e7330 351 PIRSF PIRSF006470 34 351 1.2E-104 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A616_RS30930 64282dfd84bdf602cf1f517e876e7330 351 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 56 336 4.5E-94 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 SUPERFAMILY SSF88697 5 154 8.65E-47 T 29-03-2018 IPR015947 PUA-like domain A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 SUPERFAMILY SSF52374 162 374 1.34E-85 T 29-03-2018 A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 372 1.8E-132 T 29-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 Gene3D G3DSA:3.10.400.10 4 170 2.6E-57 T 29-03-2018 A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 Pfam PF14306 PUA-like domain 4 153 3.4E-47 T 29-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 20 376 50.716 T 29-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 Gene3D G3DSA:3.40.50.620 171 372 2.8E-90 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS23480 6aab822e5dc322ec59072e2981c77b97 380 Pfam PF01747 ATP-sulfurylase 162 372 3.9E-94 T 29-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 Pfam PF08402 TOBE domain 283 359 2.4E-11 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 Gene3D G3DSA:2.40.50.140 294 351 4.3E-4 T 29-03-2018 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 SUPERFAMILY SSF52540 7 244 6.56E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 358 8.5E-111 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 SMART SM00382 31 214 3.4E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 Gene3D G3DSA:2.40.50.100 245 293 7.1E-4 T 29-03-2018 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 Pfam PF00005 ABC transporter 23 164 5.3E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 Gene3D G3DSA:3.40.50.300 2 244 1.5E-75 T 29-03-2018 A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 SUPERFAMILY SSF50331 240 359 9.23E-18 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS03680 72a2018fac57a30dffb70785deaa6065 364 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 SUPERFAMILY SSF46785 5 85 6.17E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.7E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 2.7E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.7E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 2.7E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 Gene3D G3DSA:1.10.10.10 1 88 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 Pfam PF01022 Bacterial regulatory protein, arsR family 17 64 2.6E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS04575 e5b1cd4f133968d673df4ee88e519e07 101 SMART SM00418 10 89 5.0E-29 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS31460 422c81a91736be773ce87e66c569ee28 474 Pfam PF00171 Aldehyde dehydrogenase family 14 469 1.4E-158 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS31460 422c81a91736be773ce87e66c569ee28 474 SUPERFAMILY SSF53720 3 473 7.2E-152 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS31460 422c81a91736be773ce87e66c569ee28 474 Gene3D G3DSA:3.40.605.10 1 262 1.5E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS31460 422c81a91736be773ce87e66c569ee28 474 Gene3D G3DSA:3.40.309.10 263 456 2.2E-61 T 29-03-2018 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 Gene3D G3DSA:3.40.50.1370 159 299 3.8E-39 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 297 3.5E-96 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 4 299 38.628 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 295 1.5E-20 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 Gene3D G3DSA:3.40.50.1370 2 158 1.4E-58 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 250 259 5.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 285 5.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 5.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 5.5E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 2.4E-31 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 2.4E-31 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 213 222 2.4E-31 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 254 259 2.4E-31 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 278 292 2.4E-31 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 2.4E-31 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 SUPERFAMILY SSF53671 4 299 2.49E-89 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 144 7.2E-42 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A616_RS21015 9b9154be23d794b2ca14115767370cd6 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS28595 039b01433f445208d0066747fb0210bb 361 Gene3D G3DSA:2.130.10.150 50 204 7.2E-4 T 29-03-2018 A616_RS28595 039b01433f445208d0066747fb0210bb 361 SUPERFAMILY SSF69304 163 358 9.68E-16 T 29-03-2018 A616_RS28595 039b01433f445208d0066747fb0210bb 361 Pfam PF16472 Domain of unknown function (DUF5050) 55 208 4.8E-22 T 29-03-2018 IPR032485 Domain of unknown function DUF5050 A616_RS28595 039b01433f445208d0066747fb0210bb 361 Pfam PF16472 Domain of unknown function (DUF5050) 210 358 5.1E-15 T 29-03-2018 IPR032485 Domain of unknown function DUF5050 A616_RS28595 039b01433f445208d0066747fb0210bb 361 Gene3D G3DSA:2.120.10.60 205 360 3.5E-7 T 29-03-2018 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PIRSF PIRSF036480 17 298 3.3E-116 T 29-03-2018 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 249 271 2.5E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 2.5E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 271 296 2.5E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 2.5E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 2.5E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 2.5E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 297 1.8E-123 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 SUPERFAMILY SSF55021 19 104 6.49E-17 T 29-03-2018 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 Pfam PF00551 Formyl transferase 104 279 5.5E-42 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 Pfam PF01842 ACT domain 23 82 1.0E-7 T 29-03-2018 IPR002912 ACT domain A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 SUPERFAMILY SSF53328 104 297 2.35E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 Gene3D G3DSA:3.40.50.170 101 294 2.6E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 297 46.804 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A616_RS27295 e3f67e82efffb3f5f0dcff3861c311b0 298 Gene3D G3DSA:3.30.70.260 14 100 3.9E-25 T 29-03-2018 A616_RS23655 752420494d263dc1d3fcac70852b8351 288 Pfam PF12679 ABC-2 family transporter protein 14 288 1.7E-9 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS23655 752420494d263dc1d3fcac70852b8351 288 Gene3D G3DSA:1.10.287.70 7 285 0.0042 T 29-03-2018 A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 SUPERFAMILY SSF56519 54 240 8.37E-18 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 Pfam PF00905 Penicillin binding protein transpeptidase domain 276 586 6.9E-57 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 Gene3D G3DSA:3.40.710.10 248 598 4.2E-78 T 29-03-2018 A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 SUPERFAMILY SSF56601 202 409 1.82E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 SUPERFAMILY SSF56601 444 591 1.82E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 234 6.6E-9 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS10870 a2db5810bf02639a7a91739ca4dc394e 608 Gene3D G3DSA:3.90.1310.10 24 247 2.6E-17 T 29-03-2018 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 SUPERFAMILY SSF53067 251 498 9.29E-67 T 29-03-2018 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 PIRSF PIRSF000538 3 505 4.6E-152 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 249 3.6E-71 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 Gene3D G3DSA:3.30.420.40 1 246 5.7E-72 T 29-03-2018 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 5 509 2.8E-197 T 29-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 453 8.3E-35 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 SUPERFAMILY SSF53067 5 252 7.26E-73 T 29-03-2018 A616_RS15125 f1caaebd997a4fb584a6bea807d7cd06 513 Gene3D G3DSA:3.30.420.40 247 513 4.9E-66 T 29-03-2018 A616_RS14750 beb93d2658f4a3db78d6e5e18194f0dd 689 Pfam PF01757 Acyltransferase family 14 347 1.7E-26 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS14750 beb93d2658f4a3db78d6e5e18194f0dd 689 SUPERFAMILY SSF52266 496 648 3.95E-14 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS14750 beb93d2658f4a3db78d6e5e18194f0dd 689 Gene3D G3DSA:3.40.50.1110 450 647 4.0E-23 T 29-03-2018 A616_RS23885 68efc27c640429c50d3982440d1fe781 308 SUPERFAMILY SSF46785 1 63 6.83E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23885 68efc27c640429c50d3982440d1fe781 308 Pfam PF13280 WYL domain 139 301 3.3E-21 T 29-03-2018 IPR026881 WYL domain A616_RS23885 68efc27c640429c50d3982440d1fe781 308 PIRSF PIRSF016838 1 298 4.7E-20 T 29-03-2018 IPR028349 Protein PafC A616_RS23885 68efc27c640429c50d3982440d1fe781 308 Gene3D G3DSA:1.10.10.10 1 64 7.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23885 68efc27c640429c50d3982440d1fe781 308 Pfam PF08279 HTH domain 6 61 2.2E-10 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS15520 f59a3477fab84acf641c269b0f242107 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 490 1.7E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15520 f59a3477fab84acf641c269b0f242107 515 Gene3D G3DSA:3.40.50.980 166 319 4.7E-38 T 29-03-2018 A616_RS15520 f59a3477fab84acf641c269b0f242107 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15520 f59a3477fab84acf641c269b0f242107 515 Pfam PF00501 AMP-binding enzyme 11 406 8.0E-99 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15520 f59a3477fab84acf641c269b0f242107 515 Gene3D G3DSA:3.30.300.30 401 511 5.8E-28 T 29-03-2018 A616_RS15520 f59a3477fab84acf641c269b0f242107 515 SUPERFAMILY SSF56801 7 503 1.28E-147 T 29-03-2018 A616_RS15520 f59a3477fab84acf641c269b0f242107 515 Gene3D G3DSA:3.40.50.980 3 165 9.1E-40 T 29-03-2018 A616_RS15520 f59a3477fab84acf641c269b0f242107 515 Gene3D G3DSA:2.30.38.10 320 399 1.3E-23 T 29-03-2018 A616_RS27400 5b489cbcf09a006a9588cdf79d09e0fa 311 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 29 305 6.1E-95 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A616_RS27400 5b489cbcf09a006a9588cdf79d09e0fa 311 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site A616_RS27400 5b489cbcf09a006a9588cdf79d09e0fa 311 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 307 18.655 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A616_RS27400 5b489cbcf09a006a9588cdf79d09e0fa 311 Pfam PF01040 UbiA prenyltransferase family 43 288 6.0E-61 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A616_RS27530 eaf6f7d94ac30b07fbf6d349fdae0f76 153 Gene3D G3DSA:3.10.129.10 6 144 3.8E-29 T 29-03-2018 A616_RS27530 eaf6f7d94ac30b07fbf6d349fdae0f76 153 Pfam PF03061 Thioesterase superfamily 59 133 2.4E-11 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS27530 eaf6f7d94ac30b07fbf6d349fdae0f76 153 SUPERFAMILY SSF54637 25 140 1.83E-27 T 29-03-2018 IPR029069 HotDog domain A616_RS27530 eaf6f7d94ac30b07fbf6d349fdae0f76 153 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 29 131 7.0E-22 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 Pfam PF00672 HAMP domain 302 350 2.6E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 SUPERFAMILY SSF55874 413 568 1.11E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 Pfam PF06580 Histidine kinase 366 442 3.7E-20 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 464 564 2.5E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 SMART SM00304 302 354 9.3E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 SUPERFAMILY SSF158472 302 353 7.19E-8 T 29-03-2018 A616_RS31790 40a3acf41e16e37fb917d9f5de97a341 578 Gene3D G3DSA:3.30.565.10 325 564 8.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS10345 d040fd13b7da978507ca86acd6d9b25b 270 Gene3D G3DSA:3.40.50.10090 166 262 1.4E-25 T 29-03-2018 A616_RS10345 d040fd13b7da978507ca86acd6d9b25b 270 Pfam PF02602 Uroporphyrinogen-III synthase HemD 26 255 1.2E-68 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10345 d040fd13b7da978507ca86acd6d9b25b 270 SUPERFAMILY SSF69618 12 263 4.19E-72 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10345 d040fd13b7da978507ca86acd6d9b25b 270 Gene3D G3DSA:3.40.50.10090 44 165 1.6E-34 T 29-03-2018 A616_RS15700 bd2ad34c0c6658756ff07bd7aa4f038e 142 Pfam PF12802 MarR family 36 83 2.5E-7 T 29-03-2018 A616_RS15700 bd2ad34c0c6658756ff07bd7aa4f038e 142 Gene3D G3DSA:1.10.10.10 5 134 3.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15700 bd2ad34c0c6658756ff07bd7aa4f038e 142 SMART SM00347 29 134 2.1E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15700 bd2ad34c0c6658756ff07bd7aa4f038e 142 SUPERFAMILY SSF46785 9 137 2.73E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31835 e6c69f2b25ce4bd72c595cd1627b53be 447 Pfam PF05139 Erythromycin esterase 107 440 2.2E-72 T 29-03-2018 IPR007815 Erythromycin esterase GO:0046677 A616_RS31835 e6c69f2b25ce4bd72c595cd1627b53be 447 SUPERFAMILY SSF159501 49 444 1.83E-100 T 29-03-2018 A616_RS31835 e6c69f2b25ce4bd72c595cd1627b53be 447 Gene3D G3DSA:3.40.1660.10 39 219 2.9E-24 T 29-03-2018 A616_RS31835 e6c69f2b25ce4bd72c595cd1627b53be 447 Gene3D G3DSA:3.40.1660.10 231 446 1.3E-28 T 29-03-2018 A616_RS31835 e6c69f2b25ce4bd72c595cd1627b53be 447 PIRSF PIRSF036794 30 447 3.4E-118 T 29-03-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type A616_RS21085 136d01c3fa24057c588980964ce28c19 973 SUPERFAMILY SSF89260 751 837 5.1E-12 T 29-03-2018 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 Gene3D G3DSA:2.60.120.380 852 972 8.1E-15 T 29-03-2018 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 Gene3D G3DSA:2.60.120.380 729 850 4.4E-10 T 29-03-2018 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 Pfam PF08453 Peptidase family M9 N-terminal 68 243 7.5E-43 T 29-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain A616_RS21085 136d01c3fa24057c588980964ce28c19 973 Pfam PF01752 Collagenase 280 592 2.5E-71 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 134 152 2.5E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 415 429 2.5E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 432 448 2.5E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 469 487 2.5E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 495 510 2.5E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS21085 136d01c3fa24057c588980964ce28c19 973 SUPERFAMILY SSF89260 859 967 3.66E-21 T 29-03-2018 A616_RS05535 c09a7962e36d96d454a7f6028814684b 130 Pfam PF07485 Domain of Unknown Function (DUF1259) 10 126 2.7E-31 T 29-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 Gene3D G3DSA:3.40.50.1000 1 279 3.5E-40 T 29-03-2018 IPR023214 HAD-like domain A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 ProSitePatterns PS01229 Hypothetical cof family signature 2. 228 250 - T 29-03-2018 A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 274 4.0E-58 T 29-03-2018 IPR000150 Cof family GO:0016787 A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 247 7.0E-29 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 SUPERFAMILY SSF56784 2 279 1.47E-66 T 29-03-2018 IPR023214 HAD-like domain A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 274 5.8E-59 T 29-03-2018 IPR023214 HAD-like domain A616_RS30990 2f52bf65ea2d31c5d48898a6b70d7bca 279 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 29-03-2018 A616_RS14780 c4d6f8bf16b54607d633473058947f93 314 Gene3D G3DSA:1.10.3720.10 31 302 4.5E-43 T 29-03-2018 A616_RS14780 c4d6f8bf16b54607d633473058947f93 314 SUPERFAMILY SSF161098 100 296 9.29E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14780 c4d6f8bf16b54607d633473058947f93 314 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 74 2.1E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS14780 c4d6f8bf16b54607d633473058947f93 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 313 3.1E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28665 9b724685c8cf4aac63caf682c52d430b 674 SUPERFAMILY SSF52777 11 183 4.78E-33 T 29-03-2018 A616_RS28665 9b724685c8cf4aac63caf682c52d430b 674 SUPERFAMILY SSF52777 191 440 2.45E-35 T 29-03-2018 A616_RS28665 9b724685c8cf4aac63caf682c52d430b 674 Gene3D G3DSA:3.30.559.10 3 187 3.2E-25 T 29-03-2018 A616_RS28665 9b724685c8cf4aac63caf682c52d430b 674 SUPERFAMILY SSF52777 453 653 4.67E-11 T 29-03-2018 A616_RS28665 9b724685c8cf4aac63caf682c52d430b 674 Pfam PF00668 Condensation domain 7 440 3.5E-78 T 29-03-2018 IPR001242 Condensation domain A616_RS28665 9b724685c8cf4aac63caf682c52d430b 674 Pfam PF00668 Condensation domain 562 656 5.9E-6 T 29-03-2018 IPR001242 Condensation domain A616_RS10965 deab2947968cca0ec2de50294b200089 106 Pfam PF00665 Integrase core domain 2 102 1.4E-22 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A616_RS10965 deab2947968cca0ec2de50294b200089 106 Gene3D G3DSA:3.30.420.10 1 106 1.1E-19 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS10965 deab2947968cca0ec2de50294b200089 106 SUPERFAMILY SSF53098 6 104 5.61E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS02490 9133675f1dfa63652c79db9df90514fc 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 234 2.9E-12 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS02490 9133675f1dfa63652c79db9df90514fc 337 Gene3D G3DSA:3.40.50.720 1 115 1.8E-11 T 29-03-2018 A616_RS02490 9133675f1dfa63652c79db9df90514fc 337 SUPERFAMILY SSF51735 2 314 1.97E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS02490 9133675f1dfa63652c79db9df90514fc 337 Gene3D G3DSA:3.90.25.10 170 330 2.6E-21 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 SUPERFAMILY SSF82714 179 259 6.28E-7 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 SUPERFAMILY SSF82866 269 484 1.06E-8 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Gene3D G3DSA:1.20.1640.10 265 541 6.4E-11 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Gene3D G3DSA:3.30.2090.10 176 262 2.2E-8 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Gene3D G3DSA:1.20.1640.10 816 1015 8.0E-13 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 SUPERFAMILY SSF82714 696 778 2.49E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Gene3D G3DSA:3.30.70.1430 550 635 5.9E-6 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Pfam PF00873 AcrB/AcrD/AcrF family 471 1000 1.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Pfam PF00873 AcrB/AcrD/AcrF family 11 389 1.1E-32 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 SUPERFAMILY SSF82866 777 1001 3.14E-18 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Gene3D G3DSA:3.30.2090.10 694 778 2.0E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 Gene3D G3DSA:3.30.70.1430 41 139 2.8E-9 T 29-03-2018 A616_RS27260 9ac1d3db5deff6045e34d95b9b3e8ca8 1082 SUPERFAMILY SSF82693 42 119 2.41E-6 T 29-03-2018 A616_RS09935 fe4422bdc56a048169ef6df5f314e81a 324 Pfam PF08635 Putative oxidoreductase C terminal 124 226 5.2E-9 T 29-03-2018 IPR013944 Oxidoreductase putative, C-terminal A616_RS09935 fe4422bdc56a048169ef6df5f314e81a 324 Gene3D G3DSA:3.40.50.720 1 129 1.1E-34 T 29-03-2018 A616_RS09935 fe4422bdc56a048169ef6df5f314e81a 324 Gene3D G3DSA:3.30.360.10 130 323 1.2E-29 T 29-03-2018 A616_RS09935 fe4422bdc56a048169ef6df5f314e81a 324 SUPERFAMILY SSF55347 143 285 2.29E-21 T 29-03-2018 A616_RS09935 fe4422bdc56a048169ef6df5f314e81a 324 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 120 2.3E-26 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS09935 fe4422bdc56a048169ef6df5f314e81a 324 SUPERFAMILY SSF51735 3 185 6.25E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20120 a9c4aaec3057533c506b6985d200c9e6 104 SUPERFAMILY SSF117782 1 104 3.27E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 A616_RS20120 a9c4aaec3057533c506b6985d200c9e6 104 Gene3D G3DSA:3.30.110.70 1 103 3.2E-36 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 A616_RS20120 a9c4aaec3057533c506b6985d200c9e6 104 Pfam PF01906 Putative heavy-metal-binding 1 103 1.8E-38 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 A616_RS20120 a9c4aaec3057533c506b6985d200c9e6 104 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 25.158 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 SUPERFAMILY SSF52029 183 374 1.21E-84 T 29-03-2018 IPR027409 GroEL-like apical domain A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 PRINTS PR00298 60kDa chaperonin signature 266 289 1.1E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 PRINTS PR00298 60kDa chaperonin signature 396 417 1.1E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 PRINTS PR00298 60kDa chaperonin signature 26 52 1.1E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 PRINTS PR00298 60kDa chaperonin signature 82 109 1.1E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 PRINTS PR00298 60kDa chaperonin signature 348 373 1.1E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 4.7E-256 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 Gene3D G3DSA:1.10.560.10 372 513 1.1E-27 T 29-03-2018 IPR027413 GroEL-like equatorial domain A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 SUPERFAMILY SSF54849 136 204 7.1E-27 T 29-03-2018 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 42.569 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.2E-102 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 Gene3D G3DSA:3.50.7.10 187 371 1.4E-98 T 29-03-2018 IPR027409 GroEL-like apical domain A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 Gene3D G3DSA:1.10.560.10 1 186 1.7E-35 T 29-03-2018 IPR027413 GroEL-like equatorial domain A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 SUPERFAMILY SSF48592 6 133 3.33E-80 T 29-03-2018 A616_RS03025 4156152ddef3ece5eae9c9086cc5d037 543 SUPERFAMILY SSF48592 404 518 3.33E-80 T 29-03-2018 A616_RS20665 cc77c2ff5e1a28d6bfa07dcbba0d69b2 499 Gene3D G3DSA:2.140.10.30 229 498 7.3E-11 T 29-03-2018 A616_RS20665 cc77c2ff5e1a28d6bfa07dcbba0d69b2 499 SUPERFAMILY SSF82171 282 395 2.24E-9 T 29-03-2018 A616_RS20665 cc77c2ff5e1a28d6bfa07dcbba0d69b2 499 SUPERFAMILY SSF82171 431 494 2.24E-9 T 29-03-2018 A616_RS09220 d8fb6b3d748d7c5af93f65763854f772 295 SMART SM00382 30 217 2.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09220 d8fb6b3d748d7c5af93f65763854f772 295 Gene3D G3DSA:3.40.50.300 1 274 3.2E-60 T 29-03-2018 A616_RS09220 d8fb6b3d748d7c5af93f65763854f772 295 Pfam PF00005 ABC transporter 21 168 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09220 d8fb6b3d748d7c5af93f65763854f772 295 SUPERFAMILY SSF52540 1 219 1.54E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09220 d8fb6b3d748d7c5af93f65763854f772 295 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Gene3D G3DSA:3.30.230.10 490 611 5.1E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SUPERFAMILY SSF50447 263 402 2.47E-37 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 113.369 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Gene3D G3DSA:3.40.50.300 1 285 7.9E-62 T 29-03-2018 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SMART SM00838 598 685 5.5E-58 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Pfam PF03764 Elongation factor G, domain IV 477 595 6.0E-46 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Gene3D G3DSA:3.30.70.240 612 689 5.0E-32 T 29-03-2018 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 180 2.4E-37 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.1E-35 T 29-03-2018 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SUPERFAMILY SSF54980 402 479 2.19E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SUPERFAMILY SSF52540 7 280 1.16E-110 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 2.1E-15 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Gene3D G3DSA:3.30.70.870 398 489 1.9E-35 T 29-03-2018 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SUPERFAMILY SSF54211 477 596 5.82E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Gene3D G3DSA:2.40.30.10 287 397 1.8E-32 T 29-03-2018 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Pfam PF00679 Elongation factor G C-terminus 598 683 2.6E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SMART SM00889 478 596 1.0E-72 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 1.7E-67 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01370 577c280616a87bf3f9d05c3f8ddb4b8f 692 SUPERFAMILY SSF54980 598 688 9.11E-31 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS14940 64e5477bc1b3dd627ec2d0d83e3b17a6 481 Gene3D G3DSA:3.20.20.140 59 389 4.4E-37 T 29-03-2018 A616_RS14940 64e5477bc1b3dd627ec2d0d83e3b17a6 481 SUPERFAMILY SSF51338 4 48 3.68E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS14940 64e5477bc1b3dd627ec2d0d83e3b17a6 481 SUPERFAMILY SSF51338 373 446 3.68E-27 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS14940 64e5477bc1b3dd627ec2d0d83e3b17a6 481 SUPERFAMILY SSF51556 48 374 6.81E-45 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS14940 64e5477bc1b3dd627ec2d0d83e3b17a6 481 Gene3D G3DSA:2.30.40.10 1 58 1.6E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS14940 64e5477bc1b3dd627ec2d0d83e3b17a6 481 Pfam PF01979 Amidohydrolase family 46 421 7.4E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS04390 080c69b599130e68836824d8f8c71222 371 Pfam PF07730 Histidine kinase 179 244 3.6E-10 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS04390 080c69b599130e68836824d8f8c71222 371 Gene3D G3DSA:3.30.565.10 134 250 0.1 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04390 080c69b599130e68836824d8f8c71222 371 SUPERFAMILY SSF55874 260 368 6.17E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04390 080c69b599130e68836824d8f8c71222 371 Gene3D G3DSA:3.30.565.10 251 370 1.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23380 5ad637bbd8e2e20799a3a2765a54b48f 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 376 7.0E-100 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A616_RS23380 5ad637bbd8e2e20799a3a2765a54b48f 390 SUPERFAMILY SSF53383 12 380 4.5E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS23380 5ad637bbd8e2e20799a3a2765a54b48f 390 Gene3D G3DSA:3.40.640.10 9 245 6.3E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS23380 5ad637bbd8e2e20799a3a2765a54b48f 390 Gene3D G3DSA:3.90.1150.10 246 389 8.4E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS23380 5ad637bbd8e2e20799a3a2765a54b48f 390 PIRSF PIRSF000390 2 384 1.5E-106 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 Gene3D G3DSA:1.10.10.10 1 70 9.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 SUPERFAMILY SSF51306 84 204 7.85E-37 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 Pfam PF01726 LexA DNA binding domain 1 65 2.0E-28 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 206 4.0E-79 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 Hamap MF_00015 LexA repressor [lexA]. 3 206 34.935 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 SUPERFAMILY SSF46785 3 70 1.07E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 Gene3D G3DSA:2.10.109.10 90 206 5.9E-27 T 29-03-2018 A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 Pfam PF00717 Peptidase S24-like 124 190 2.7E-17 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 8.3E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 8.3E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A616_RS19075 4fc4d802f952ac132ac4170f69c14f71 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 8.3E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 SUPERFAMILY SSF118215 6 382 5.89E-80 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 Pfam PF00375 Sodium:dicarboxylate symporter family 6 381 1.9E-79 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 Gene3D G3DSA:1.10.3860.10 1 387 4.1E-64 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 PRINTS PR00173 Glutamate-aspartate symporter signature 336 356 1.5E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.5E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 PRINTS PR00173 Glutamate-aspartate symporter signature 273 299 1.5E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS06770 9097bd3a4761739a0fcf4acd5771b602 388 PRINTS PR00173 Glutamate-aspartate symporter signature 71 96 1.5E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS29020 0d0c6ffa7c64393c06f51986d5aa82dc 275 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29020 0d0c6ffa7c64393c06f51986d5aa82dc 275 SMART SM00382 28 247 7.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS29020 0d0c6ffa7c64393c06f51986d5aa82dc 275 SUPERFAMILY SSF52540 4 226 9.13E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29020 0d0c6ffa7c64393c06f51986d5aa82dc 275 Pfam PF00005 ABC transporter 21 167 2.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS29020 0d0c6ffa7c64393c06f51986d5aa82dc 275 Gene3D G3DSA:3.40.50.300 1 246 3.1E-59 T 29-03-2018 A616_RS30820 c5dc32129f9c60ff04323ceb812923bf 144 SUPERFAMILY SSF55804 3 142 7.06E-40 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A616_RS30820 c5dc32129f9c60ff04323ceb812923bf 144 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 48 64 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain A616_RS30820 c5dc32129f9c60ff04323ceb812923bf 144 Gene3D G3DSA:3.40.930.10 1 144 2.3E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A616_RS30820 c5dc32129f9c60ff04323ceb812923bf 144 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 142 5.2E-33 T 29-03-2018 IPR002178 PTS EIIA type-2 domain A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 Pfam PF00158 Sigma-54 interaction domain 144 311 1.3E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 SUPERFAMILY SSF55785 4 108 1.51E-13 T 29-03-2018 IPR000014 PAS domain A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 SMART SM00382 164 312 1.5E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 SUPERFAMILY SSF46689 357 450 1.49E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 Pfam PF08448 PAS fold 13 111 1.1E-7 T 29-03-2018 IPR013656 PAS fold-4 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 SMART SM00091 2 69 0.0032 T 29-03-2018 IPR000014 PAS domain A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 SUPERFAMILY SSF52540 144 388 2.42E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 Gene3D G3DSA:3.30.450.20 3 121 3.3E-18 T 29-03-2018 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 Gene3D G3DSA:1.10.10.60 394 451 9.6E-8 T 29-03-2018 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 4 117 2.8E-10 T 29-03-2018 IPR000014 PAS domain A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 Gene3D G3DSA:3.40.50.300 126 330 5.0E-34 T 29-03-2018 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS07455 7138a211d64398ce6a764ac22ced0b68 456 Gene3D G3DSA:1.10.8.60 331 393 3.8E-22 T 29-03-2018 A616_RS14475 28fc5f3c4283abaab7de99f506cbbdc5 343 Hamap MF_01873 Ribosomal RNA large subunit methyltransferase Cfr [cfr]. 1 343 65.203 T 29-03-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6828 A616_RS14475 28fc5f3c4283abaab7de99f506cbbdc5 343 Gene3D G3DSA:3.20.20.70 8 336 3.8E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS14475 28fc5f3c4283abaab7de99f506cbbdc5 343 SUPERFAMILY SSF102114 101 293 2.06E-14 T 29-03-2018 A616_RS14475 28fc5f3c4283abaab7de99f506cbbdc5 343 Pfam PF04055 Radical SAM superfamily 105 263 5.5E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS14475 28fc5f3c4283abaab7de99f506cbbdc5 343 PIRSF PIRSF006004 3 343 4.9E-94 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS14475 28fc5f3c4283abaab7de99f506cbbdc5 343 TIGRFAM TIGR04432 rSAM_Cfr: 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr 4 341 1.4E-192 T 29-03-2018 IPR022881 Ribosomal RNA large subunit methyltransferase, Cfr GO:0070475 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6828 A616_RS05485 617f39385dd424599d445df84a03810b 190 SUPERFAMILY SSF55729 7 63 1.19E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS05485 617f39385dd424599d445df84a03810b 190 SUPERFAMILY SSF55729 93 166 1.19E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS05485 617f39385dd424599d445df84a03810b 190 Gene3D G3DSA:3.40.630.30 2 187 4.2E-7 T 29-03-2018 A616_RS05485 617f39385dd424599d445df84a03810b 190 Pfam PF00583 Acetyltransferase (GNAT) family 15 134 1.5E-4 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 1.4E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 SMART SM00382 34 234 4.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 Gene3D G3DSA:3.40.50.300 2 329 1.0E-82 T 29-03-2018 A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 SUPERFAMILY SSF52540 33 308 6.08E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 7.9E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS04635 a6b9ad6dad5b923b0492fe5c8a47008a 330 Pfam PF00005 ABC transporter 25 184 2.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS05080 a4137b15a7da3462dd931eaba4ef2dc1 239 Gene3D G3DSA:3.40.50.300 1 236 1.6E-65 T 29-03-2018 A616_RS05080 a4137b15a7da3462dd931eaba4ef2dc1 239 Pfam PF00005 ABC transporter 21 169 4.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS05080 a4137b15a7da3462dd931eaba4ef2dc1 239 SMART SM00382 30 223 2.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS05080 a4137b15a7da3462dd931eaba4ef2dc1 239 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS05080 a4137b15a7da3462dd931eaba4ef2dc1 239 SUPERFAMILY SSF52540 1 232 1.43E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05545 e96a6baccf7bf471edc5d091468a156f 234 Gene3D G3DSA:3.40.50.300 1 230 3.5E-60 T 29-03-2018 A616_RS05545 e96a6baccf7bf471edc5d091468a156f 234 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS05545 e96a6baccf7bf471edc5d091468a156f 234 Pfam PF00005 ABC transporter 24 167 1.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS05545 e96a6baccf7bf471edc5d091468a156f 234 SUPERFAMILY SSF52540 4 225 3.99E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05545 e96a6baccf7bf471edc5d091468a156f 234 SMART SM00382 33 215 1.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14290 36c05a7012b528486851a716b3ac2333 289 SUPERFAMILY SSF52540 3 238 4.87E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14290 36c05a7012b528486851a716b3ac2333 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14290 36c05a7012b528486851a716b3ac2333 289 Gene3D G3DSA:3.40.50.300 2 255 6.2E-71 T 29-03-2018 A616_RS14290 36c05a7012b528486851a716b3ac2333 289 SMART SM00382 36 221 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14290 36c05a7012b528486851a716b3ac2333 289 Pfam PF00005 ABC transporter 27 174 6.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14290 36c05a7012b528486851a716b3ac2333 289 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 276 1.4E-113 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 375 557 1.3E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 277 8.1E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 SUPERFAMILY SSF161098 15 279 8.04E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 Gene3D G3DSA:1.10.3720.10 302 559 7.8E-27 T 29-03-2018 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 Gene3D G3DSA:1.10.3720.10 18 281 2.2E-41 T 29-03-2018 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 SUPERFAMILY SSF161098 295 549 1.03E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31580 4493f2b2899bb42dcbeb887afbe8da18 566 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 16 559 3.1E-219 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 Gene3D G3DSA:1.10.1740.10 302 382 8.2E-30 T 29-03-2018 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 SUPERFAMILY SSF69055 290 379 3.66E-30 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 PIRSF PIRSF006205 1 382 4.0E-160 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 3.6E-160 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 SUPERFAMILY SSF51735 2 149 1.06E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 145 228 6.4E-42 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 SUPERFAMILY SSF55347 125 263 3.6E-60 T 29-03-2018 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 381 46.415 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 Gene3D G3DSA:3.40.50.720 1 149 8.6E-52 T 29-03-2018 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 131 1.7E-44 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS19845 5e7e10bbeef9780bc30d349b1d2fd361 382 Pfam PF13288 DXP reductoisomerase C-terminal domain 260 376 2.1E-41 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A616_RS28980 ccae19e70e2578a94ffccefaae937a16 131 SUPERFAMILY SSF46626 28 128 4.23E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS28980 ccae19e70e2578a94ffccefaae937a16 131 Gene3D G3DSA:1.10.760.10 43 130 2.3E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS28980 ccae19e70e2578a94ffccefaae937a16 131 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 62 127 2.6E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS28980 ccae19e70e2578a94ffccefaae937a16 131 PIRSF PIRSF000025 9 131 2.0E-28 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A616_RS28980 ccae19e70e2578a94ffccefaae937a16 131 Pfam PF14141 YqzM-like protein 8 38 1.5E-6 T 29-03-2018 IPR025416 YqzM-like protein A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 SUPERFAMILY SSF56194 196 300 2.75E-37 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 200 298 1.9E-31 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 SUPERFAMILY SSF56176 14 193 4.0E-42 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 Gene3D G3DSA:3.90.78.10 202 298 2.0E-31 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 301 92.358 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 299 9.3E-93 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 Pfam PF01565 FAD binding domain 35 162 2.0E-19 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 Gene3D G3DSA:3.30.465.10 90 201 1.3E-32 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS21290 e92bb13856db6c88dcdf4f40f8a6a016 301 Gene3D G3DSA:3.30.43.10 14 88 3.2E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:3.30.450.40 1317 1506 5.9E-23 T 29-03-2018 IPR029016 GAF domain-like A616_RS31220 670554d5429555645fa5320683befcca 1971 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1853 1968 2.1E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:3.30.565.10 1795 1970 1.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:1.10.510.10 106 280 6.0E-36 T 29-03-2018 A616_RS31220 670554d5429555645fa5320683befcca 1971 SUPERFAMILY SSF55874 1808 1967 2.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31220 670554d5429555645fa5320683befcca 1971 SUPERFAMILY SSF52540 298 576 5.15E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31220 670554d5429555645fa5320683befcca 1971 SUPERFAMILY SSF56112 5 268 2.7E-49 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS31220 670554d5429555645fa5320683befcca 1971 SMART SM00065 1337 1489 5.3E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS31220 670554d5429555645fa5320683befcca 1971 Pfam PF01590 GAF domain 1338 1476 4.4E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS31220 670554d5429555645fa5320683befcca 1971 SUPERFAMILY SSF55781 1325 1498 1.22E-22 T 29-03-2018 IPR029016 GAF domain-like A616_RS31220 670554d5429555645fa5320683befcca 1971 SMART SM00387 1850 1969 3.2E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31220 670554d5429555645fa5320683befcca 1971 Pfam PF00069 Protein kinase domain 25 260 5.1E-29 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:3.30.450.20 1507 1647 3.3E-6 T 29-03-2018 A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:3.40.50.300 302 546 3.2E-11 T 29-03-2018 A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:3.30.200.20 10 105 6.2E-4 T 29-03-2018 A616_RS31220 670554d5429555645fa5320683befcca 1971 Gene3D G3DSA:1.25.40.10 740 1316 9.1E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31220 670554d5429555645fa5320683befcca 1971 Pfam PF13191 AAA ATPase domain 301 489 1.3E-42 T 29-03-2018 A616_RS31220 670554d5429555645fa5320683befcca 1971 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1953 1966 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31220 670554d5429555645fa5320683befcca 1971 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1895 1909 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31220 670554d5429555645fa5320683befcca 1971 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1929 1947 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 Gene3D G3DSA:3.40.190.10 175 265 4.2E-20 T 29-03-2018 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 Gene3D G3DSA:1.10.10.10 1 83 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 SUPERFAMILY SSF46785 2 103 8.88E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 Pfam PF03466 LysR substrate binding domain 87 288 6.9E-36 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 Gene3D G3DSA:3.40.190.10 88 174 1.1E-15 T 29-03-2018 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 SUPERFAMILY SSF53850 87 288 4.34E-34 T 29-03-2018 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07555 de848586dfd3014459ac95824a8e6aec 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.4E-24 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS01955 f45769c1c86340feadd6fd4a2f22d783 316 SUPERFAMILY SSF54593 5 295 9.16E-42 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS01955 f45769c1c86340feadd6fd4a2f22d783 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 8.0E-25 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS01955 f45769c1c86340feadd6fd4a2f22d783 316 Gene3D G3DSA:3.10.180.10 2 146 4.0E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS01955 f45769c1c86340feadd6fd4a2f22d783 316 Gene3D G3DSA:3.10.180.10 147 311 5.4E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 105 118 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 186 417 1.5E-75 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 PIRSF PIRSF000185 7 419 1.4E-170 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 SUPERFAMILY SSF53223 3 188 3.52E-71 T 29-03-2018 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 40 168 1.4E-56 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 SUPERFAMILY SSF51735 186 418 3.87E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 SMART SM00839 188 417 7.2E-107 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 Gene3D G3DSA:3.40.50.720 186 419 1.9E-80 T 29-03-2018 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 345 356 1.0E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 177 199 1.0E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 219 239 1.0E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 97 111 1.0E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS04910 9ff40d22fb10f1c9e3f17939390b7517 419 Gene3D G3DSA:3.40.50.10860 38 173 2.2E-54 T 29-03-2018 A616_RS28840 7121f2337f830031133f6947eb4dcccb 179 SUPERFAMILY SSF53098 73 122 2.09E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS28840 7121f2337f830031133f6947eb4dcccb 179 Pfam PF13276 HTH-like domain 5 57 3.4E-12 T 29-03-2018 IPR025948 HTH-like domain A616_RS28840 7121f2337f830031133f6947eb4dcccb 179 Gene3D G3DSA:3.30.420.10 67 153 1.7E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 SUPERFAMILY SSF51735 1 151 3.16E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 298 8.1E-135 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 SUPERFAMILY SSF48179 165 297 6.8E-39 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 Gene3D G3DSA:1.10.1040.10 169 297 2.1E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 235 247 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 5.8E-30 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 22 5.8E-30 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 5.8E-30 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 5.8E-30 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 276 6.3E-23 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 SMART SM01350 167 298 2.7E-5 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 152 2.2E-44 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A616_RS15135 d867f3616f35f826429b66b67f5dd296 298 Gene3D G3DSA:3.40.50.720 1 168 5.7E-30 T 29-03-2018 A616_RS08810 ad2292022b1afe6e4edf9ec7d70fc71d 277 SUPERFAMILY SSF161098 69 256 1.11E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS08810 ad2292022b1afe6e4edf9ec7d70fc71d 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 275 1.6E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS08810 ad2292022b1afe6e4edf9ec7d70fc71d 277 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 44 9.7E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS08810 ad2292022b1afe6e4edf9ec7d70fc71d 277 Gene3D G3DSA:1.10.3720.10 1 264 2.7E-45 T 29-03-2018 A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 265 418 5.4E-35 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 SMART SM00283 192 457 1.3E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 SUPERFAMILY SSF46458 25 169 2.23E-29 T 29-03-2018 IPR009050 Globin-like A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 Pfam PF11563 Protoglobin 24 177 2.9E-40 T 29-03-2018 A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 Pfam PF13682 Chemoreceptor zinc-binding domain 469 536 1.1E-13 T 29-03-2018 IPR025991 Chemoreceptor zinc-binding domain A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 Gene3D G3DSA:1.10.490.10 6 178 1.0E-32 T 29-03-2018 A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 SUPERFAMILY SSF58104 198 448 6.41E-56 T 29-03-2018 A616_RS24270 66f892bea13d0841de33f9f4e93fdf8a 573 Gene3D G3DSA:1.10.287.950 206 435 1.0E-47 T 29-03-2018 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 8 136 3.7E-42 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 Gene3D G3DSA:2.40.100.10 1 141 5.2E-51 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 112 127 1.0E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 1.0E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 84 99 1.0E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 99 111 1.0E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 1.0E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 SUPERFAMILY SSF50891 4 137 2.48E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS13460 396ca2425b12529c688165dcc1583c9d 143 PIRSF PIRSF001467 2 142 9.0E-39 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A616_RS23820 d0177f88d28a719dbb960a74fa2eb6bf 124 Pfam PF14534 Domain of unknown function (DUF4440) 6 114 1.2E-11 T 29-03-2018 IPR027843 Domain of unknown function DUF4440 A616_RS23820 d0177f88d28a719dbb960a74fa2eb6bf 124 SUPERFAMILY SSF54427 6 120 4.86E-27 T 29-03-2018 IPR032710 NTF2-like domain A616_RS23820 d0177f88d28a719dbb960a74fa2eb6bf 124 Gene3D G3DSA:3.10.450.50 2 120 5.8E-21 T 29-03-2018 A616_RS10240 fe0e8993938212471144c276e7e91da0 172 TIGRFAM TIGR02954 Sig70_famx3: RNA polymerase sigma-70 factor, TIGR02954 family 2 165 9.2E-59 T 29-03-2018 IPR014300 RNA polymerase sigma-V type A616_RS10240 fe0e8993938212471144c276e7e91da0 172 SUPERFAMILY SSF88659 105 163 2.8E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10240 fe0e8993938212471144c276e7e91da0 172 Pfam PF08281 Sigma-70, region 4 111 161 4.5E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10240 fe0e8993938212471144c276e7e91da0 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 164 3.6E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10240 fe0e8993938212471144c276e7e91da0 172 SUPERFAMILY SSF88946 3 97 5.49E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10240 fe0e8993938212471144c276e7e91da0 172 Gene3D G3DSA:1.10.10.10 98 171 1.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10240 fe0e8993938212471144c276e7e91da0 172 Pfam PF04542 Sigma-70 region 2 21 88 3.4E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10240 fe0e8993938212471144c276e7e91da0 172 Gene3D G3DSA:1.10.1740.10 1 97 1.8E-20 T 29-03-2018 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 Gene3D G3DSA:1.20.1250.20 246 463 3.4E-31 T 29-03-2018 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 4.9E-5 T 29-03-2018 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 4.9E-5 T 29-03-2018 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 161 185 4.9E-5 T 29-03-2018 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 Pfam PF07690 Major Facilitator Superfamily 17 403 2.1E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 SUPERFAMILY SSF103473 242 447 1.44E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 SUPERFAMILY SSF103473 6 195 1.44E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 417 1.6E-72 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A616_RS12190 d8cc06ea456efbc65cc404c07926f427 469 Gene3D G3DSA:1.20.1250.20 5 196 6.7E-38 T 29-03-2018 A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 Gene3D G3DSA:3.30.420.40 226 360 6.9E-35 T 29-03-2018 A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 ProSitePatterns PS01125 ROK family signature. 219 246 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 Pfam PF13412 Winged helix-turn-helix DNA-binding 16 60 4.0E-7 T 29-03-2018 A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 Gene3D G3DSA:1.10.10.10 2 76 1.6E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 SUPERFAMILY SSF53067 84 384 1.73E-52 T 29-03-2018 A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 SUPERFAMILY SSF46785 11 76 6.83E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 Pfam PF00480 ROK family 85 382 1.1E-54 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS04920 f58e6a1bdc5541c90622221a78eb8b92 395 Gene3D G3DSA:3.30.420.40 81 225 1.3E-32 T 29-03-2018 A616_RS21925 e707b7cf293816eb775de58875edf814 671 SUPERFAMILY SSF48334 17 282 2.09E-18 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS21925 e707b7cf293816eb775de58875edf814 671 SMART SM00534 321 506 2.0E-51 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS21925 e707b7cf293816eb775de58875edf814 671 PIRSF PIRSF005814 1 569 1.0E-178 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A616_RS21925 e707b7cf293816eb775de58875edf814 671 PIRSF PIRSF005814 540 668 4.0 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A616_RS21925 e707b7cf293816eb775de58875edf814 671 SMART SM00533 9 309 1.2E-5 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS21925 e707b7cf293816eb775de58875edf814 671 SUPERFAMILY SSF52540 290 505 1.11E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21925 e707b7cf293816eb775de58875edf814 671 Gene3D G3DSA:1.10.1420.10 17 282 0.01 T 29-03-2018 A616_RS21925 e707b7cf293816eb775de58875edf814 671 Gene3D G3DSA:3.40.50.300 286 557 3.6E-28 T 29-03-2018 A616_RS21925 e707b7cf293816eb775de58875edf814 671 Pfam PF00488 MutS domain V 324 505 5.2E-33 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 10 316 7.5E-129 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 Gene3D G3DSA:3.40.50.2020 7 159 1.7E-67 T 29-03-2018 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 SMART SM01400 9 125 8.4E-83 T 29-03-2018 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 Gene3D G3DSA:3.40.50.2020 160 292 1.7E-42 T 29-03-2018 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 315 1.8E-24 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 SUPERFAMILY SSF53271 74 307 1.74E-67 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 125 4.6E-51 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A616_RS00685 3da4c34cfb9e0941affb9784efe64042 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 9 316 51.31 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A616_RS22815 57c721cec875724c669fa9438e1524e7 370 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 11 332 1.2E-108 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS22815 57c721cec875724c669fa9438e1524e7 370 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 361 43.612 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS22815 57c721cec875724c669fa9438e1524e7 370 Pfam PF13378 Enolase C-terminal domain-like 147 356 2.9E-45 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS22815 57c721cec875724c669fa9438e1524e7 370 Gene3D G3DSA:3.20.20.120 131 348 2.3E-59 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS22815 57c721cec875724c669fa9438e1524e7 370 SUPERFAMILY SSF54826 1 125 4.21E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS22815 57c721cec875724c669fa9438e1524e7 370 Gene3D G3DSA:3.30.390.10 1 130 2.6E-24 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS22815 57c721cec875724c669fa9438e1524e7 370 SMART SM00922 142 235 6.2E-24 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A616_RS22815 57c721cec875724c669fa9438e1524e7 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 124 5.2E-8 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A616_RS22815 57c721cec875724c669fa9438e1524e7 370 SUPERFAMILY SSF51604 113 364 5.24E-66 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 SUPERFAMILY SSF52768 13 287 1.24E-83 T 29-03-2018 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 PRINTS PR00116 Arginase signature 210 239 5.2E-11 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 PRINTS PR00116 Arginase signature 73 88 5.2E-11 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 PIRSF PIRSF036979 1 289 1.8E-98 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 TIGRFAM TIGR01230 agmatinase: agmatinase 11 285 5.1E-109 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 Pfam PF00491 Arginase family 23 284 1.2E-77 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 ProSitePatterns PS01053 Arginase family signature. 213 234 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A616_RS30215 35ee4dbdaa696ab35ded625684100055 289 Gene3D G3DSA:3.40.800.10 15 289 1.4E-81 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 SUPERFAMILY SSF82693 552 634 4.13E-6 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 SUPERFAMILY SSF82866 776 1000 8.11E-46 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 SUPERFAMILY SSF82693 43 133 2.96E-10 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Gene3D G3DSA:3.30.70.1430 41 142 9.4E-13 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Pfam PF00873 AcrB/AcrD/AcrF family 6 994 9.9E-183 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Gene3D G3DSA:3.30.2090.10 179 264 4.1E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Gene3D G3DSA:3.30.2090.10 688 778 2.2E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 SUPERFAMILY SSF82866 290 487 1.09E-36 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 8.6E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 8.6E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 8.6E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 8.6E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 8.6E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Gene3D G3DSA:1.20.1640.10 279 502 1.5E-39 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 SUPERFAMILY SSF82714 693 774 1.83E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 SUPERFAMILY SSF82714 185 260 1.83E-8 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Gene3D G3DSA:3.30.70.1430 553 639 1.5E-9 T 29-03-2018 A616_RS18810 686030a5f7a3188df73ec644d324dd26 1013 Gene3D G3DSA:1.20.1640.10 783 996 7.9E-39 T 29-03-2018 A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 Gene3D G3DSA:3.40.50.1000 4 95 1.2E-16 T 29-03-2018 IPR023214 HAD-like domain A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 Gene3D G3DSA:3.30.1240.10 96 163 9.7E-25 T 29-03-2018 A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 Gene3D G3DSA:3.40.50.1000 164 257 2.0E-16 T 29-03-2018 IPR023214 HAD-like domain A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 SUPERFAMILY SSF56784 1 256 9.07E-66 T 29-03-2018 IPR023214 HAD-like domain A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 2.5E-60 T 29-03-2018 IPR000150 Cof family GO:0016787 A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 1.8E-60 T 29-03-2018 IPR023214 HAD-like domain A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 4.7E-26 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 29-03-2018 A616_RS05800 595c688b9d9203f927be95aa7fc47e44 258 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 29-03-2018 A616_RS07885 43eea7c77dd8c472a526d08541323d86 481 Gene3D G3DSA:3.30.1490.20 231 296 3.6E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS07885 43eea7c77dd8c472a526d08541323d86 481 Gene3D G3DSA:3.30.470.20 297 430 1.3E-13 T 29-03-2018 A616_RS07885 43eea7c77dd8c472a526d08541323d86 481 SUPERFAMILY SSF56059 222 422 1.93E-11 T 29-03-2018 A616_RS07885 43eea7c77dd8c472a526d08541323d86 481 Pfam PF14398 YheC/D like ATP-grasp 198 456 1.3E-78 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS16075 cc501a51f3bedf208e20243f8a92239a 198 Pfam PF13649 Methyltransferase domain 40 129 2.0E-9 T 29-03-2018 A616_RS16075 cc501a51f3bedf208e20243f8a92239a 198 Gene3D G3DSA:3.40.50.150 1 179 1.2E-14 T 29-03-2018 A616_RS16075 cc501a51f3bedf208e20243f8a92239a 198 SUPERFAMILY SSF53335 3 198 4.51E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS04225 1c27da00eade5268e6cbe1e8a80da631 65 SUPERFAMILY SSF140500 9 60 1.09E-7 T 29-03-2018 A616_RS04225 1c27da00eade5268e6cbe1e8a80da631 65 Pfam PF09388 Spo0E like sporulation regulatory protein 12 54 6.1E-9 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 50 75 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 1.3E-93 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 Gene3D G3DSA:1.10.287.70 575 642 4.7E-17 T 29-03-2018 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 59 505 9.6E-144 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 SUPERFAMILY SSF81442 48 559 1.19E-178 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28535 abc637773578e24bf5726f06741bb6c5 657 Gene3D G3DSA:1.20.210.10 46 560 1.6E-190 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07375 69396a067f428122c080c27e8f5b54d4 346 Gene3D G3DSA:3.40.50.10210 69 326 2.1E-109 T 29-03-2018 A616_RS07375 69396a067f428122c080c27e8f5b54d4 346 SUPERFAMILY SSF52733 4 344 4.71E-121 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07375 69396a067f428122c080c27e8f5b54d4 346 Pfam PF02277 Phosphoribosyltransferase 8 343 1.8E-137 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07375 69396a067f428122c080c27e8f5b54d4 346 Gene3D G3DSA:1.10.1610.10 2 68 3.2E-31 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07375 69396a067f428122c080c27e8f5b54d4 346 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 10 345 38.286 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07375 69396a067f428122c080c27e8f5b54d4 346 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 12 343 2.3E-139 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS23580 2c4038f1377fc90387f4d0e8ad256654 166 Pfam PF00877 NlpC/P60 family 53 164 9.0E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS23580 2c4038f1377fc90387f4d0e8ad256654 166 Gene3D G3DSA:2.30.260.10 88 165 2.1E-19 T 29-03-2018 A616_RS23580 2c4038f1377fc90387f4d0e8ad256654 166 Gene3D G3DSA:3.90.1720.10 21 87 9.6E-17 T 29-03-2018 A616_RS23580 2c4038f1377fc90387f4d0e8ad256654 166 SUPERFAMILY SSF54001 34 165 2.7E-36 T 29-03-2018 A616_RS16215 50afe4d55bec494a4cc84e713d441aad 334 SUPERFAMILY SSF51556 1 328 4.19E-90 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS16215 50afe4d55bec494a4cc84e713d441aad 334 Pfam PF04909 Amidohydrolase 3 327 5.8E-57 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS16215 50afe4d55bec494a4cc84e713d441aad 334 Gene3D G3DSA:3.20.20.140 1 329 1.3E-68 T 29-03-2018 A616_RS17070 83b0e0a67e27c9fd38d9b736ebc76b33 118 Pfam PF10711 Hypothetical protein (DUF2513) 2 95 2.0E-20 T 29-03-2018 IPR019650 Protein of unknown function DUF2513 A616_RS02510 6547b8814fcf21d6a42d1c018d267d74 144 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 141 4.2E-20 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A616_RS02510 6547b8814fcf21d6a42d1c018d267d74 144 PIRSF PIRSF030780 10 142 3.0E-10 T 29-03-2018 IPR016956 Inner membrane protein YdjM A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 SMART SM00448 2 114 1.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 Pfam PF04397 LytTr DNA-binding domain 161 258 8.2E-27 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 Gene3D G3DSA:3.40.50.2300 1 144 2.4E-28 T 29-03-2018 A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 SMART SM00850 160 259 2.5E-32 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 Gene3D G3DSA:2.20.25.10 222 259 2.4E-11 T 29-03-2018 A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 SUPERFAMILY SSF52172 2 135 2.56E-30 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 Pfam PF00072 Response regulator receiver domain 4 113 8.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23915 a08932386f7fdf7f5badbbcc1e277f93 260 Gene3D G3DSA:2.40.50.40 150 220 3.7E-18 T 29-03-2018 A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 SMART SM00487 21 218 3.3E-64 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 Gene3D G3DSA:3.40.50.300 220 515 1.3E-47 T 29-03-2018 A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 SUPERFAMILY SSF52540 70 357 3.18E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 Gene3D G3DSA:3.40.50.300 10 219 9.3E-60 T 29-03-2018 A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 SMART SM00490 254 335 4.1E-35 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 Pfam PF00270 DEAD/DEAH box helicase 26 191 7.8E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 Pfam PF00271 Helicase conserved C-terminal domain 227 335 2.6E-30 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS30840 32d8512a527aff04cf8fb57d84fc0301 520 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A616_RS29330 551cdfc8e327bb2b7c8cc4858fd5d8aa 179 SMART SM00855 3 141 7.9E-6 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS29330 551cdfc8e327bb2b7c8cc4858fd5d8aa 179 PIRSF PIRSF000709 1 149 0.0014 T 29-03-2018 A616_RS29330 551cdfc8e327bb2b7c8cc4858fd5d8aa 179 Gene3D G3DSA:3.40.50.1240 1 179 3.1E-30 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS29330 551cdfc8e327bb2b7c8cc4858fd5d8aa 179 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 175 2.4E-25 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS29330 551cdfc8e327bb2b7c8cc4858fd5d8aa 179 SUPERFAMILY SSF53254 1 171 4.84E-30 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 Gene3D G3DSA:1.10.10.10 127 213 8.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 SMART SM00448 2 116 5.6E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 SUPERFAMILY SSF52172 2 132 1.07E-29 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 SUPERFAMILY SSF46894 134 211 1.63E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 SMART SM00421 147 204 1.2E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 5.0E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 Gene3D G3DSA:3.40.50.2300 1 126 3.4E-29 T 29-03-2018 A616_RS15825 842ea547f394ec735d0dcea9bd9e8dcb 214 Pfam PF00072 Response regulator receiver domain 4 116 6.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS21990 44798ecb1902c8d836fbdcd599adb959 322 PIRSF PIRSF036979 24 322 4.6E-39 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS21990 44798ecb1902c8d836fbdcd599adb959 322 Hamap MF_00737 Formimidoylglutamase [hutG]. 8 316 38.99 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A616_RS21990 44798ecb1902c8d836fbdcd599adb959 322 TIGRFAM TIGR01227 hutG: formimidoylglutamase 13 314 5.3E-95 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A616_RS21990 44798ecb1902c8d836fbdcd599adb959 322 Gene3D G3DSA:3.40.800.10 4 322 3.5E-86 T 29-03-2018 A616_RS21990 44798ecb1902c8d836fbdcd599adb959 322 SUPERFAMILY SSF52768 12 319 1.33E-80 T 29-03-2018 A616_RS21990 44798ecb1902c8d836fbdcd599adb959 322 Pfam PF00491 Arginase family 47 316 2.8E-61 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 Gene3D G3DSA:3.40.50.300 2 323 5.5E-86 T 29-03-2018 A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 Pfam PF00005 ABC transporter 33 183 3.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 SUPERFAMILY SSF52540 5 255 6.83E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 9.4E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 SMART SM00382 41 233 2.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS11310 6412e7dd597f5f98c9e9f973ea71d9aa 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 4.0E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 PIRSF PIRSF000441 1 219 4.6E-84 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 8.1E-9 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 3.9E-6 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 Gene3D G3DSA:2.160.10.10 55 220 3.1E-39 T 29-03-2018 A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 3.3E-77 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 Gene3D G3DSA:1.10.3130.10 1 54 4.2E-26 T 29-03-2018 A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 6.5E-6 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A616_RS01275 8ee749b95decc784cb75c751a9a09f77 221 SUPERFAMILY SSF51161 4 168 1.16E-54 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Gene3D G3DSA:3.30.450.20 132 213 7.4E-7 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SMART SM00091 131 197 3.5E-4 T 29-03-2018 IPR000014 PAS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SMART SM00091 240 306 2.6 T 29-03-2018 IPR000014 PAS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 400 413 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 665 4.9E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 665 685 4.9E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 188 5.8E-6 T 29-03-2018 IPR000014 PAS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Gene3D G3DSA:3.40.50.300 371 548 5.9E-27 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SUPERFAMILY SSF52540 376 621 1.1E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SUPERFAMILY SSF55785 131 210 2.74E-6 T 29-03-2018 IPR000014 PAS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SUPERFAMILY SSF46689 590 684 1.88E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SUPERFAMILY SSF55785 221 334 1.87E-8 T 29-03-2018 IPR000014 PAS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Pfam PF13426 PAS domain 143 187 6.9E-4 T 29-03-2018 IPR000014 PAS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Gene3D G3DSA:1.10.8.60 550 616 8.2E-20 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Pfam PF00571 CBS domain 10 59 5.1E-6 T 29-03-2018 IPR000644 CBS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Pfam PF00571 CBS domain 70 122 3.7E-5 T 29-03-2018 IPR000644 CBS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Gene3D G3DSA:1.10.10.60 617 685 2.2E-17 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Pfam PF00158 Sigma-54 interaction domain 377 542 1.6E-69 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Gene3D G3DSA:3.30.450.20 214 370 5.1E-8 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SMART SM00116 14 59 0.56 T 29-03-2018 IPR000644 CBS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SMART SM00116 75 123 1.4 T 29-03-2018 IPR000644 CBS domain A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 463 478 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Pfam PF02954 Bacterial regulatory protein, Fis family 643 682 8.4E-15 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 Gene3D G3DSA:3.10.580.10 3 131 1.5E-17 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SUPERFAMILY SSF54631 4 136 6.49E-19 T 29-03-2018 A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 590 599 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS15320 6e97e4c369897047aa2f042beb43cb16 688 SMART SM00382 396 540 1.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 2.1E-239 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 Gene3D G3DSA:3.30.1490.20 124 209 3.4E-24 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.8E-84 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 Gene3D G3DSA:3.30.470.20 210 444 9.7E-108 T 29-03-2018 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 Gene3D G3DSA:3.40.50.20 1 123 1.2E-55 T 29-03-2018 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 SUPERFAMILY SSF52440 1 113 2.59E-51 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.4E-48 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 SUPERFAMILY SSF56059 83 349 1.68E-74 T 29-03-2018 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 SUPERFAMILY SSF51246 331 444 1.31E-48 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 2.7E-45 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS13095 64a86749328b9d9940b80e000e4d4f5a 451 SMART SM00878 336 442 6.8E-73 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 Gene3D G3DSA:1.20.1250.20 190 382 5.5E-29 T 29-03-2018 A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 Gene3D G3DSA:3.40.50.10600 383 496 1.4E-28 T 29-03-2018 A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 SMART SM00091 382 448 0.0013 T 29-03-2018 IPR000014 PAS domain A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 SUPERFAMILY SSF55785 391 490 2.27E-25 T 29-03-2018 IPR000014 PAS domain A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 Gene3D G3DSA:1.20.1250.20 1 185 2.8E-21 T 29-03-2018 A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 Pfam PF07690 Major Facilitator Superfamily 13 339 1.8E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 SUPERFAMILY SSF103473 3 378 8.11E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 Pfam PF13426 PAS domain 393 490 1.3E-11 T 29-03-2018 IPR000014 PAS domain A616_RS26140 be01217bb65ea6a5a8e3f22bb17f64f3 499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 380 493 2.0E-14 T 29-03-2018 IPR000014 PAS domain A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 Gene3D G3DSA:1.10.230.10 235 328 2.0E-29 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 SUPERFAMILY SSF48256 8 366 3.93E-118 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 Gene3D G3DSA:1.10.580.10 2 234 5.0E-80 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 Pfam PF00285 Citrate synthase, C-terminal domain 10 358 2.6E-117 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PRINTS PR00143 Citrate synthase signature 328 342 2.0E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PRINTS PR00143 Citrate synthase signature 308 324 2.0E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PRINTS PR00143 Citrate synthase signature 194 222 2.0E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PRINTS PR00143 Citrate synthase signature 123 136 2.0E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PRINTS PR00143 Citrate synthase signature 172 187 2.0E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PRINTS PR00143 Citrate synthase signature 247 267 2.0E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 PIRSF PIRSF001369 1 367 1.1E-123 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type A616_RS02530 b26e722ef03add9a004211d122e5dd69 367 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 3.0E-150 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 1.5E-120 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 Gene3D G3DSA:1.10.10.10 258 328 4.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 7.3E-34 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 SUPERFAMILY SSF52540 21 253 6.3E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 Gene3D G3DSA:3.40.50.300 19 182 2.2E-30 T 29-03-2018 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 SUPERFAMILY SSF46785 258 329 4.56E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 330 2.0E-31 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 Gene3D G3DSA:1.10.8.60 185 255 4.0E-32 T 29-03-2018 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 332 176.87 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A616_RS10660 7d8dc0cf09ebc7e5cdfb821e6467c971 332 SMART SM00382 52 179 4.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 Pfam PF00366 Ribosomal protein S17 13 79 7.3E-33 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 Gene3D G3DSA:2.40.50.140 8 85 2.4E-31 T 29-03-2018 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 83 24.397 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 1.2E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 1.2E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 1.2E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 8 79 4.0E-28 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 79 1.0E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01445 b410d72613d08907334b1ef0ef11b85b 88 SUPERFAMILY SSF50249 8 85 8.57E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS15325 b1918e031f6f78e66dbb29d0469ea2b1 416 Gene3D G3DSA:1.20.1250.20 196 409 2.4E-22 T 29-03-2018 A616_RS15325 b1918e031f6f78e66dbb29d0469ea2b1 416 SUPERFAMILY SSF103473 2 403 1.57E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS15325 b1918e031f6f78e66dbb29d0469ea2b1 416 Pfam PF07690 Major Facilitator Superfamily 9 350 1.0E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS15325 b1918e031f6f78e66dbb29d0469ea2b1 416 Gene3D G3DSA:1.20.1250.20 1 194 1.7E-35 T 29-03-2018 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Gene3D G3DSA:1.10.10.350 389 487 1.6E-22 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Gene3D G3DSA:3.40.50.620 5 133 9.2E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Gene3D G3DSA:3.40.50.620 134 246 7.1E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 485 2.9E-176 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 1.5E-115 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Gene3D G3DSA:1.10.1160.10 247 333 5.6E-32 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.21 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 SUPERFAMILY SSF52374 5 316 6.44E-113 T 29-03-2018 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 1.5E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 1.5E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 1.5E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 1.5E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 1.5E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 Gene3D G3DSA:1.10.8.70 334 383 4.3E-7 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A616_RS01270 96e0213090f6bc92a3e92dfe41c0c3db 488 SUPERFAMILY SSF48163 297 483 7.46E-41 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 PIRSF PIRSF016578 2 378 8.9E-19 T 29-03-2018 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 SUPERFAMILY SSF47203 227 379 5.48E-64 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 SUPERFAMILY SSF56645 1 242 9.95E-93 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.7E-41 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 Gene3D G3DSA:2.40.110.10 121 217 1.9E-39 T 29-03-2018 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 Gene3D G3DSA:1.20.140.10 218 380 3.2E-66 T 29-03-2018 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 Gene3D G3DSA:1.10.540.10 1 120 2.0E-42 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 4.3E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS30155 acf28283feabacc33aaf9e764c90e0f7 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 4.2E-26 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS32205 67cc48c0dec99d315f4a1d6ab5be2bc5 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 10 25 2.7E-10 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS32205 67cc48c0dec99d315f4a1d6ab5be2bc5 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 10 24 2.1E-6 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS24640 158bbb1a8b3d5c2b8b49c9d0b9305f06 344 SUPERFAMILY SSF55811 161 327 2.44E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS24640 158bbb1a8b3d5c2b8b49c9d0b9305f06 344 Pfam PF00293 NUDIX domain 167 271 4.8E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS24640 158bbb1a8b3d5c2b8b49c9d0b9305f06 344 Gene3D G3DSA:3.90.79.10 130 336 4.1E-35 T 29-03-2018 A616_RS24640 158bbb1a8b3d5c2b8b49c9d0b9305f06 344 SUPERFAMILY SSF54593 1 126 1.79E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24640 158bbb1a8b3d5c2b8b49c9d0b9305f06 344 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 121 1.6E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS24640 158bbb1a8b3d5c2b8b49c9d0b9305f06 344 Gene3D G3DSA:3.10.180.10 6 129 3.8E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS19120 1c0b0c413ddea0ba4c57498064c7ffe1 171 SUPERFAMILY SSF55961 13 168 8.89E-43 T 29-03-2018 A616_RS19120 1c0b0c413ddea0ba4c57498064c7ffe1 171 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 167 4.8E-26 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS19120 1c0b0c413ddea0ba4c57498064c7ffe1 171 Gene3D G3DSA:3.30.530.20 1 170 3.5E-27 T 29-03-2018 IPR023393 START-like domain A616_RS10480 8c0c0536471fca70f8e391b22b6d7e23 79 Pfam PF14209 Domain of unknown function (DUF4321) 30 74 1.4E-12 T 29-03-2018 IPR025470 Protein of unknown function DUF4321 A616_RS28345 778a38948de3fae6194d5007a52fed37 488 Pfam PF00144 Beta-lactamase 11 370 5.5E-62 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS28345 778a38948de3fae6194d5007a52fed37 488 Gene3D G3DSA:3.40.710.10 3 373 3.2E-76 T 29-03-2018 A616_RS28345 778a38948de3fae6194d5007a52fed37 488 SUPERFAMILY SSF56601 11 127 6.2E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS28345 778a38948de3fae6194d5007a52fed37 488 SUPERFAMILY SSF56601 156 360 6.2E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS26815 eb16c24fd2ee69a8431a897f926f8139 126 SUPERFAMILY SSF51230 3 125 5.63E-46 T 29-03-2018 IPR011053 Single hybrid motif A616_RS26815 eb16c24fd2ee69a8431a897f926f8139 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A616_RS26815 eb16c24fd2ee69a8431a897f926f8139 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.532 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A616_RS26815 eb16c24fd2ee69a8431a897f926f8139 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 5.7E-57 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A616_RS26815 eb16c24fd2ee69a8431a897f926f8139 126 Gene3D G3DSA:2.40.50.100 5 126 2.1E-50 T 29-03-2018 A616_RS26815 eb16c24fd2ee69a8431a897f926f8139 126 Pfam PF01597 Glycine cleavage H-protein 7 126 5.1E-49 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate A616_RS29490 a6f20b1153e913943405caf1342fd502 363 SUPERFAMILY SSF51569 2 314 3.05E-86 T 29-03-2018 A616_RS29490 a6f20b1153e913943405caf1342fd502 363 Pfam PF03102 NeuB family 24 289 1.5E-100 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 A616_RS29490 a6f20b1153e913943405caf1342fd502 363 Gene3D G3DSA:3.90.1210.10 294 359 7.0E-22 T 29-03-2018 A616_RS29490 a6f20b1153e913943405caf1342fd502 363 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 4 356 2.6E-153 T 29-03-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|KEGG: 00900+2.5.1.10|MetaCyc: PWY-5123|MetaCyc: PWY-6749|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7131|MetaCyc: PWY-7721|MetaCyc: PWY-7736 A616_RS29490 a6f20b1153e913943405caf1342fd502 363 SUPERFAMILY SSF51269 296 357 3.53E-19 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 A616_RS29490 a6f20b1153e913943405caf1342fd502 363 Gene3D G3DSA:3.20.20.70 1 289 1.2E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS17060 f1c538c7deceb88ddaca5a7f76de5531 99 Gene3D G3DSA:3.40.50.1390 1 99 4.2E-14 T 29-03-2018 A616_RS17060 f1c538c7deceb88ddaca5a7f76de5531 99 SMART SM00857 2 99 5.3E-4 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS17060 f1c538c7deceb88ddaca5a7f76de5531 99 SUPERFAMILY SSF53041 1 98 1.2E-13 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS17060 f1c538c7deceb88ddaca5a7f76de5531 99 Pfam PF00239 Resolvase, N terminal domain 2 98 1.0E-11 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 395 419 - T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 Pfam PF01019 Gamma-glutamyltranspeptidase 53 569 7.1E-169 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 Gene3D G3DSA:3.30.457.10 653 677 0.064 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 Gene3D G3DSA:3.30.457.10 550 652 0.064 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 281 300 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 251 267 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 395 413 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 419 437 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 474 491 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 135 153 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 60 85 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 450 465 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 153 172 1.0E-72 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 SUPERFAMILY SSF56235 34 574 1.14E-172 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS20495 0b00dd6da3657e278a9fc5258e95959a 677 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 38 566 7.8E-175 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS15315 a67af825f836e4306ed9a3000689e2b6 397 Gene3D G3DSA:1.20.1250.20 1 194 2.6E-33 T 29-03-2018 A616_RS15315 a67af825f836e4306ed9a3000689e2b6 397 Pfam PF07690 Major Facilitator Superfamily 12 349 3.1E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS15315 a67af825f836e4306ed9a3000689e2b6 397 SUPERFAMILY SSF103473 7 390 6.15E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS15315 a67af825f836e4306ed9a3000689e2b6 397 Gene3D G3DSA:1.20.1250.20 197 396 2.1E-26 T 29-03-2018 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 169 217 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 Gene3D G3DSA:1.10.760.10 250 342 1.3E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 Pfam PF00034 Cytochrome c 252 336 1.7E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 SUPERFAMILY SSF49503 122 288 9.58E-51 T 29-03-2018 IPR008972 Cupredoxin A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 50 109 5.0E-10 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 SUPERFAMILY SSF46626 243 336 1.83E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 Gene3D G3DSA:1.10.287.90 30 115 1.5E-23 T 29-03-2018 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 SUPERFAMILY SSF81464 16 113 2.62E-21 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 148 222 1.1E-21 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 35 233 4.5E-66 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27565 6b9ba45410184f887a231694f13c63c2 342 Gene3D G3DSA:2.60.40.420 116 249 9.1E-50 T 29-03-2018 IPR008972 Cupredoxin A616_RS26455 49cda49f4d82301e6cf2397a7e719b6a 324 SUPERFAMILY SSF56655 2 316 1.71E-103 T 29-03-2018 A616_RS26455 49cda49f4d82301e6cf2397a7e719b6a 324 PIRSF PIRSF004532 1 323 2.7E-141 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A616_RS26455 49cda49f4d82301e6cf2397a7e719b6a 324 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 313 1.3E-138 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A616_RS26455 49cda49f4d82301e6cf2397a7e719b6a 324 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 321 9.6E-124 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A616_RS26455 49cda49f4d82301e6cf2397a7e719b6a 324 Gene3D G3DSA:3.30.540.10 1 160 1.6E-55 T 29-03-2018 A616_RS26455 49cda49f4d82301e6cf2397a7e719b6a 324 Gene3D G3DSA:3.30.540.10 161 324 7.1E-57 T 29-03-2018 A616_RS30715 d3ddd3cd707b01e885232a85856586a1 486 PIRSF PIRSF012293 2 484 1.0E-134 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA A616_RS30715 d3ddd3cd707b01e885232a85856586a1 486 Pfam PF06277 Ethanolamine utilisation protein EutA 6 482 2.6E-147 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA A616_RS30715 d3ddd3cd707b01e885232a85856586a1 486 Gene3D G3DSA:3.30.420.40 7 122 0.22 T 29-03-2018 A616_RS30715 d3ddd3cd707b01e885232a85856586a1 486 SUPERFAMILY SSF53067 9 182 2.99E-6 T 29-03-2018 A616_RS30715 d3ddd3cd707b01e885232a85856586a1 486 Gene3D G3DSA:3.30.420.150 123 370 1.4E-6 T 29-03-2018 A616_RS11050 cbb9edac46c4ea42c9860c6dc45f5623 167 SMART SM01058 1 111 2.0E-27 T 29-03-2018 IPR003711 CarD-like/TRCF domain A616_RS11050 cbb9edac46c4ea42c9860c6dc45f5623 167 Pfam PF02559 CarD-like/TRCF domain 2 110 2.7E-18 T 29-03-2018 IPR003711 CarD-like/TRCF domain A616_RS11050 cbb9edac46c4ea42c9860c6dc45f5623 167 SUPERFAMILY SSF141259 1 65 3.4E-12 T 29-03-2018 IPR003711 CarD-like/TRCF domain A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 Gene3D G3DSA:3.40.50.300 1 150 1.9E-29 T 29-03-2018 A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 Gene3D G3DSA:3.40.50.300 151 285 2.2E-35 T 29-03-2018 A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 275 1.6E-83 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 Pfam PF13361 UvrD-like helicase C-terminal domain 280 622 2.0E-74 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 Gene3D G3DSA:3.40.50.300 286 387 1.1E-24 T 29-03-2018 A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 779 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 SUPERFAMILY SSF52540 5 649 5.32E-185 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03970 5f1969d3b310c433f89d7e560a99e7f9 781 Gene3D G3DSA:3.40.50.300 392 660 4.1E-51 T 29-03-2018 A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 SUPERFAMILY SSF161111 11 230 6.8E-29 T 29-03-2018 A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 Gene3D G3DSA:1.20.1510.10 14 228 7.5E-25 T 29-03-2018 A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 SUPERFAMILY SSF160240 232 305 5.89E-11 T 29-03-2018 A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 Gene3D G3DSA:3.30.70.1350 229 309 9.3E-9 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 Pfam PF16916 Dimerisation domain of Zinc Transporter 234 304 7.4E-7 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 Pfam PF01545 Cation efflux family 18 228 1.4E-26 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS05035 19b9ece24c5bf73e547937798b234d2e 325 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 17 305 7.5E-37 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 Pfam PF00731 AIR carboxylase 6 152 6.0E-67 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 PIRSF PIRSF001338 1 162 7.9E-70 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 159 33.915 T 29-03-2018 IPR033747 Class I PurE A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 SUPERFAMILY SSF52255 5 159 2.88E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 159 2.4E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 Gene3D G3DSA:3.40.50.7700 1 161 7.4E-70 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A616_RS03205 dc50820f8d8b65dead9b3397834e971b 162 SMART SM01001 4 155 2.0E-106 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 SMART SM01209 101 293 6.3E-133 T 29-03-2018 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 417 9.3E-31 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Gene3D G3DSA:3.30.1490.20 85 187 4.3E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Gene3D G3DSA:3.40.50.20 2 84 1.3E-34 T 29-03-2018 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 SUPERFAMILY SSF56059 102 343 8.84E-60 T 29-03-2018 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Gene3D G3DSA:3.90.600.10 327 420 5.3E-35 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Gene3D G3DSA:3.30.470.20 189 325 2.0E-59 T 29-03-2018 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 419 42.986 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 SUPERFAMILY SSF52440 1 101 2.3E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 SMART SM01210 327 419 2.1E-48 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 3.6E-82 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 4.0E-34 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 SUPERFAMILY SSF51246 326 419 9.94E-29 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A616_RS03600 6113185234a5b8ebbdc39f2fccd9740a 425 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 419 4.9E-166 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 Pfam PF02867 Ribonucleotide reductase, barrel domain 162 679 9.3E-124 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 371 382 6.3E-24 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 415 438 6.3E-24 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 454 476 6.3E-24 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 237 256 6.3E-24 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 482 505 6.3E-24 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 PRINTS PR01183 Ribonucleotide reductase large chain signature 564 591 6.3E-24 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 SUPERFAMILY SSF48168 4 160 4.05E-37 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 2 695 2.4E-298 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 553 575 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 SUPERFAMILY SSF51998 161 684 1.59E-160 T 29-03-2018 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 Pfam PF08343 Ribonucleotide reductase N-terminal 3 81 1.1E-19 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 86 683 2.6E-154 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 84 157 9.0E-8 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16560 9672ff4ae2d456d453157bc673885abd 695 Gene3D G3DSA:3.20.70.20 62 687 3.5E-144 T 29-03-2018 A616_RS07070 376f94865d9052a0b01fb9f798667c2d 202 Pfam PF00510 Cytochrome c oxidase subunit III 24 200 5.7E-17 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07070 376f94865d9052a0b01fb9f798667c2d 202 Gene3D G3DSA:1.20.120.80 17 202 9.0E-50 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07070 376f94865d9052a0b01fb9f798667c2d 202 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 23 202 8.3E-71 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 A616_RS07070 376f94865d9052a0b01fb9f798667c2d 202 SUPERFAMILY SSF81452 11 200 3.4E-57 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 137 1.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 151 171 1.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 117 1.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 SMART SM00347 58 161 9.0E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 SUPERFAMILY SSF46785 38 176 8.53E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 Pfam PF01047 MarR family 73 125 8.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08250 bf0f968bc0c5235b30a891b284e3d299 183 Gene3D G3DSA:1.10.10.10 34 180 1.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 SUPERFAMILY SSF56176 358 443 2.48E-16 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 Pfam PF01595 Domain of unknown function DUF21 15 210 9.2E-53 T 29-03-2018 IPR002550 Domain of unknown function DUF21 A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 SMART SM01091 360 438 3.1E-14 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 SMART SM00116 296 344 0.41 T 29-03-2018 IPR000644 CBS domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 SMART SM00116 234 283 0.017 T 29-03-2018 IPR000644 CBS domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 Gene3D G3DSA:3.20.20.70 151 357 2.0E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 Pfam PF03471 Transporter associated domain 361 436 2.5E-15 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 SUPERFAMILY SSF54631 220 356 1.89E-32 T 29-03-2018 A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 Pfam PF00571 CBS domain 226 277 1.7E-5 T 29-03-2018 IPR000644 CBS domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 Pfam PF00571 CBS domain 295 344 5.2E-8 T 29-03-2018 IPR000644 CBS domain A616_RS22220 55ddd8c176b47fd6807441c0587e75d9 454 Gene3D G3DSA:3.30.465.10 358 438 1.0E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS06170 c57e324ce10d9a34708d34c0d55ab41b 431 Gene3D G3DSA:1.10.260.40 2 85 2.1E-5 T 29-03-2018 A616_RS06170 c57e324ce10d9a34708d34c0d55ab41b 431 Gene3D G3DSA:1.20.1250.10 168 248 1.3E-5 T 29-03-2018 A616_RS06170 c57e324ce10d9a34708d34c0d55ab41b 431 Gene3D G3DSA:1.25.40.10 249 386 2.7E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS06170 c57e324ce10d9a34708d34c0d55ab41b 431 SUPERFAMILY SSF48452 179 283 6.45E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS06170 c57e324ce10d9a34708d34c0d55ab41b 431 SUPERFAMILY SSF48452 114 149 6.45E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS14745 562e6e21d6e8587b3f0720b9eb7100fe 63 Gene3D G3DSA:3.30.70.1260 30 58 1.4E-4 T 29-03-2018 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Pfam PF17203 Single cache domain 3 29 151 1.1E-15 T 29-03-2018 IPR033463 Single cache domain 3 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 SUPERFAMILY SSF55785 205 293 2.09E-9 T 29-03-2018 IPR000014 PAS domain A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Gene3D G3DSA:3.30.450.20 204 301 5.7E-12 T 29-03-2018 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 SMART SM00387 405 516 1.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 SMART SM00091 201 266 9.7E-6 T 29-03-2018 IPR000014 PAS domain A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Gene3D G3DSA:1.10.287.130 302 349 2.0E-17 T 29-03-2018 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Gene3D G3DSA:3.30.450.20 22 159 4.4E-18 T 29-03-2018 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 460 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 494 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 513 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Pfam PF13426 PAS domain 212 301 4.8E-6 T 29-03-2018 IPR000014 PAS domain A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 SUPERFAMILY SSF55874 385 513 2.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 514 4.2E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 SUPERFAMILY SSF103190 26 155 2.9E-31 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 SUPERFAMILY SSF55890 308 360 1.03E-13 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 307 362 3.9E-12 T 29-03-2018 A616_RS07445 0da39be37e306b0459ac151dcc555b2e 523 Gene3D G3DSA:3.30.565.10 350 523 7.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04490 dee6c93ea7caadd22734abb914ccc244 388 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 350 5.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04490 dee6c93ea7caadd22734abb914ccc244 388 Pfam PF07730 Histidine kinase 194 257 4.7E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS04490 dee6c93ea7caadd22734abb914ccc244 388 Gene3D G3DSA:3.30.565.10 264 388 1.9E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04490 dee6c93ea7caadd22734abb914ccc244 388 SUPERFAMILY SSF55874 269 387 6.81E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04490 dee6c93ea7caadd22734abb914ccc244 388 Gene3D G3DSA:1.20.1270.60 143 245 3.6E-4 T 29-03-2018 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Gene3D G3DSA:3.30.70.870 391 467 3.2E-11 T 29-03-2018 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Pfam PF00009 Elongation factor Tu GTP binding domain 15 279 4.2E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 SUPERFAMILY SSF54980 395 467 2.95E-14 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 SUPERFAMILY SSF50447 263 395 1.25E-27 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Gene3D G3DSA:3.40.50.300 83 273 5.6E-28 T 29-03-2018 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 150 2.9E-21 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Pfam PF16658 Class II release factor RF3, C-terminal domain 389 511 2.5E-44 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Gene3D G3DSA:3.40.50.300 6 82 2.0E-8 T 29-03-2018 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 6 524 50.062 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 Gene3D G3DSA:2.40.30.10 274 385 3.9E-16 T 29-03-2018 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 SUPERFAMILY SSF52540 11 279 6.68E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 PRINTS PR00315 GTP-binding elongation factor signature 17 30 1.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 PRINTS PR00315 GTP-binding elongation factor signature 67 75 1.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 PRINTS PR00315 GTP-binding elongation factor signature 103 114 1.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 PRINTS PR00315 GTP-binding elongation factor signature 87 97 1.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.9E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS12455 09686df53d136ddfdfe6afd50e4418ef 532 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 10 522 1.5E-211 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 Gene3D G3DSA:3.40.50.2300 1 129 2.4E-40 T 29-03-2018 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 SMART SM00862 157 234 1.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 Gene3D G3DSA:1.10.10.10 130 238 1.4E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 234 2.6E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 SMART SM00448 5 115 2.3E-47 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 SUPERFAMILY SSF46894 134 236 1.81E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 Pfam PF00072 Response regulator receiver domain 7 115 6.7E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS13515 2e385e8f6705a509d38680ed97a11566 238 SUPERFAMILY SSF52172 3 126 5.83E-44 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 Pfam PF00581 Rhodanese-like domain 163 264 2.8E-14 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 Pfam PF00581 Rhodanese-like domain 6 128 1.7E-21 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 SUPERFAMILY SSF52821 146 274 3.01E-31 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 Gene3D G3DSA:3.40.250.10 154 275 4.3E-25 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 Gene3D G3DSA:3.40.250.10 1 150 4.0E-35 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 SMART SM00450 152 268 2.0E-14 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 SMART SM00450 5 131 1.1E-24 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12525 4548f89f5d26b9e2b7bb746fddf7085c 275 SUPERFAMILY SSF52821 3 152 4.32E-43 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS13160 f701b1f37f0b1997ae65c05a76525351 285 SUPERFAMILY SSF111331 3 281 7.72E-83 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A616_RS13160 f701b1f37f0b1997ae65c05a76525351 285 Gene3D G3DSA:2.60.200.30 137 259 3.2E-38 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A616_RS13160 f701b1f37f0b1997ae65c05a76525351 285 Hamap MF_00361 NAD kinase [nadK]. 2 282 32.427 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A616_RS13160 f701b1f37f0b1997ae65c05a76525351 285 Pfam PF01513 ATP-NAD kinase 3 265 1.8E-60 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A616_RS13160 f701b1f37f0b1997ae65c05a76525351 285 Gene3D G3DSA:3.40.50.10330 1 136 2.8E-37 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A616_RS22580 3d9dc9fbd6062347f24ac4d96874615c 160 PIRSF PIRSF021377 1 157 2.8E-61 T 29-03-2018 IPR014229 Sporulation protein YtfJ A616_RS22580 3d9dc9fbd6062347f24ac4d96874615c 160 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 125 5.3E-31 T 29-03-2018 IPR014229 Sporulation protein YtfJ A616_RS22580 3d9dc9fbd6062347f24ac4d96874615c 160 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 134 3.2E-55 T 29-03-2018 IPR014229 Sporulation protein YtfJ A616_RS10230 381f1634716cff03412e8c97e3fb9b69 148 Gene3D G3DSA:3.40.630.30 1 148 2.2E-25 T 29-03-2018 A616_RS10230 381f1634716cff03412e8c97e3fb9b69 148 SUPERFAMILY SSF55729 8 138 8.14E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS10230 381f1634716cff03412e8c97e3fb9b69 148 Pfam PF13673 Acetyltransferase (GNAT) domain 40 131 1.7E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 SUPERFAMILY SSF143597 39 201 1.83E-48 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 Gene3D G3DSA:3.40.1700.10 72 200 2.4E-32 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 Hamap MF_00838 Diadenylate cyclase [dacB]. 15 202 32.885 T 29-03-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 Gene3D G3DSA:1.10.287.770 9 70 8.3E-22 T 29-03-2018 A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 PIRSF PIRSF004793 5 204 6.4E-58 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 79 196 5.7E-39 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS14705 59255ac3dcfbc799b2ae3ff5773b0c65 204 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 3 70 1.3E-26 T 29-03-2018 IPR019457 Uncharacterised domain YojJ, N-terminal A616_RS00870 ad99b7e97cd5e5d826ea6f407ef79eae 255 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 5.0E-82 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A616_RS00870 ad99b7e97cd5e5d826ea6f407ef79eae 255 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.169 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A616_RS00870 ad99b7e97cd5e5d826ea6f407ef79eae 255 SUPERFAMILY SSF53067 124 253 4.1E-41 T 29-03-2018 A616_RS00870 ad99b7e97cd5e5d826ea6f407ef79eae 255 Pfam PF03309 Type III pantothenate kinase 2 206 4.4E-72 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A616_RS00870 ad99b7e97cd5e5d826ea6f407ef79eae 255 Gene3D G3DSA:3.30.420.40 89 255 1.3E-64 T 29-03-2018 A616_RS00870 ad99b7e97cd5e5d826ea6f407ef79eae 255 SUPERFAMILY SSF53067 1 122 3.52E-37 T 29-03-2018 A616_RS24965 b9a5a94ecda73ef6af9701a453e3f4c2 575 Gene3D G3DSA:1.10.3720.10 23 292 1.2E-48 T 29-03-2018 A616_RS24965 b9a5a94ecda73ef6af9701a453e3f4c2 575 Gene3D G3DSA:1.10.3720.10 310 568 1.2E-42 T 29-03-2018 A616_RS24965 b9a5a94ecda73ef6af9701a453e3f4c2 575 SUPERFAMILY SSF161098 23 289 4.58E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24965 b9a5a94ecda73ef6af9701a453e3f4c2 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 383 563 2.2E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24965 b9a5a94ecda73ef6af9701a453e3f4c2 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 285 2.2E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24965 b9a5a94ecda73ef6af9701a453e3f4c2 575 SUPERFAMILY SSF161098 305 569 1.7E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 SUPERFAMILY SSF88659 116 180 2.62E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 SUPERFAMILY SSF88946 1 104 3.14E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 179 1.6E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 Gene3D G3DSA:1.10.1740.10 1 92 4.4E-22 T 29-03-2018 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 Pfam PF08281 Sigma-70, region 4 125 173 7.1E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 Pfam PF04542 Sigma-70 region 2 21 91 7.9E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13855 0d1c24d02baf917cfa257a9e325f390b 196 Gene3D G3DSA:1.10.10.10 93 182 3.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09355 e339e738b519e0aee31d176d7d7c5b64 380 Gene3D G3DSA:1.10.10.10 69 181 2.5E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09355 e339e738b519e0aee31d176d7d7c5b64 380 Gene3D G3DSA:3.40.1440.10 277 379 4.2E-16 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS09355 e339e738b519e0aee31d176d7d7c5b64 380 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 179 247 7.9E-27 T 29-03-2018 IPR018656 Domain of unknown function DUF2087 A616_RS09355 e339e738b519e0aee31d176d7d7c5b64 380 SUPERFAMILY SSF82771 279 368 9.68E-7 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS13680 808aec631e002ecac2eb12598f23773b 350 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 11 332 38.566 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 198 219 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 190 330 1.2E-51 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 Gene3D G3DSA:3.40.50.720 9 188 2.7E-48 T 29-03-2018 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 Gene3D G3DSA:1.10.1040.10 190 340 1.5E-52 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 SUPERFAMILY SSF48179 190 341 6.97E-55 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 12 169 1.4E-57 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 SUPERFAMILY SSF51735 12 188 3.79E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PIRSF PIRSF000114 7 340 5.0E-109 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 183 207 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 208 232 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 143 163 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 15 32 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 65 92 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS13680 808aec631e002ecac2eb12598f23773b 350 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 248 265 2.7E-48 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A616_RS03170 91db044417e206969538445fd7c0fac5 750 SUPERFAMILY SSF54001 424 584 4.77E-38 T 29-03-2018 A616_RS03170 91db044417e206969538445fd7c0fac5 750 SMART SM00460 498 573 6.9E-18 T 29-03-2018 IPR002931 Transglutaminase-like A616_RS03170 91db044417e206969538445fd7c0fac5 750 Gene3D G3DSA:3.90.260.10 443 589 1.7E-24 T 29-03-2018 IPR002931 Transglutaminase-like A616_RS03170 91db044417e206969538445fd7c0fac5 750 Pfam PF13559 Domain of unknown function (DUF4129) 674 730 2.9E-7 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 A616_RS03170 91db044417e206969538445fd7c0fac5 750 Pfam PF01841 Transglutaminase-like superfamily 447 571 2.2E-27 T 29-03-2018 IPR002931 Transglutaminase-like A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 36 654 9.0E-130 T 29-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 338 654 5.0E-93 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 Gene3D G3DSA:1.50.10.20 325 660 1.5E-86 T 29-03-2018 A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 SUPERFAMILY SSF48239 60 332 2.2E-46 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 Gene3D G3DSA:1.50.10.20 57 324 1.5E-51 T 29-03-2018 A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 31 656 2.0E-139 T 29-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 SUPERFAMILY SSF48239 334 656 2.35E-84 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A616_RS21120 4a001e3e46333052937ee29f95a5af05 660 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 36 325 2.9E-80 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 SUPERFAMILY SSF55200 79 160 2.22E-14 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 79 160 3.1E-14 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 3 64 4.5E-17 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 159 1.8E-30 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 Gene3D G3DSA:3.10.20.80 1 76 8.9E-18 T 29-03-2018 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 SUPERFAMILY SSF54364 2 73 6.28E-15 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 A616_RS19470 81853f984b03a90014d0b11d0a8fb541 161 Gene3D G3DSA:3.30.110.10 77 161 1.2E-17 T 29-03-2018 A616_RS27330 75e4a433307b14086a38e210304bb387 162 Gene3D G3DSA:1.10.1660.10 61 137 1.9E-9 T 29-03-2018 A616_RS27330 75e4a433307b14086a38e210304bb387 162 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 4.0E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27330 75e4a433307b14086a38e210304bb387 162 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 4.0E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27330 75e4a433307b14086a38e210304bb387 162 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 4.0E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27330 75e4a433307b14086a38e210304bb387 162 SUPERFAMILY SSF46955 5 113 2.12E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS27330 75e4a433307b14086a38e210304bb387 162 SMART SM00422 5 74 8.0E-30 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27330 75e4a433307b14086a38e210304bb387 162 Pfam PF13411 MerR HTH family regulatory protein 6 72 1.6E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27330 75e4a433307b14086a38e210304bb387 162 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS27330 75e4a433307b14086a38e210304bb387 162 Gene3D G3DSA:1.10.1660.10 1 60 1.1E-24 T 29-03-2018 A616_RS25210 049f8828c4ebd4f39fe07a3a7ca6efa7 258 SMART SM00382 29 229 1.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25210 049f8828c4ebd4f39fe07a3a7ca6efa7 258 Pfam PF00005 ABC transporter 21 180 3.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25210 049f8828c4ebd4f39fe07a3a7ca6efa7 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 5.5E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A616_RS25210 049f8828c4ebd4f39fe07a3a7ca6efa7 258 Gene3D G3DSA:3.40.50.300 1 257 1.1E-55 T 29-03-2018 A616_RS25210 049f8828c4ebd4f39fe07a3a7ca6efa7 258 SUPERFAMILY SSF52540 5 253 3.49E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Gene3D G3DSA:3.30.450.20 73 163 8.2E-18 T 29-03-2018 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Pfam PF02743 Cache domain 37 260 8.3E-29 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 SUPERFAMILY SSF58104 318 352 5.89E-76 T 29-03-2018 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 SUPERFAMILY SSF58104 385 653 5.89E-76 T 29-03-2018 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Gene3D G3DSA:1.10.287.950 296 406 1.4E-10 T 29-03-2018 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Gene3D G3DSA:1.10.287.950 407 655 1.0E-55 T 29-03-2018 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Pfam PF00672 HAMP domain 298 346 6.4E-16 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 SMART SM00283 379 654 1.1E-89 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Gene3D G3DSA:3.30.450.20 164 267 7.5E-15 T 29-03-2018 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 SMART SM00304 298 350 1.9E-16 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 425 608 7.8E-49 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 SUPERFAMILY SSF103190 79 183 5.1E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 506 535 5.1E-8 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 5.1E-8 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS05810 c2c0f7ffaee402c0708e6b85ff970a05 655 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 554 583 5.1E-8 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 Pfam PF01842 ACT domain 266 323 1.0E-8 T 29-03-2018 IPR002912 ACT domain A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 SUPERFAMILY SSF53633 4 240 3.01E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 Pfam PF13840 ACT domain 336 398 1.4E-13 T 29-03-2018 IPR027795 GATS-like ACT domain A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 Gene3D G3DSA:3.30.70.260 235 328 2.8E-24 T 29-03-2018 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 PIRSF PIRSF000726 56 409 8.3E-127 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 PIRSF PIRSF000726 1 61 1.5E-20 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 SUPERFAMILY SSF55021 327 403 4.73E-20 T 29-03-2018 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 Gene3D G3DSA:3.30.70.260 329 400 4.4E-18 T 29-03-2018 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 Gene3D G3DSA:3.40.1160.10 1 234 2.2E-70 T 29-03-2018 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 401 6.0E-135 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 401 8.1E-143 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 Pfam PF00696 Amino acid kinase family 3 230 2.6E-51 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS09770 aafa03377776f08287aded4b2689b7d8 413 SUPERFAMILY SSF55021 250 324 3.38E-19 T 29-03-2018 A616_RS13975 0b39cad15311ec248633ec9c435381a6 301 Gene3D G3DSA:3.60.15.10 41 300 1.6E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS13975 0b39cad15311ec248633ec9c435381a6 301 SUPERFAMILY SSF56281 53 296 3.66E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS14960 16dcb8c2c0a6d153f0c79f02d25281f5 286 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 23 286 39.943 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A616_RS14960 16dcb8c2c0a6d153f0c79f02d25281f5 286 SUPERFAMILY SSF140959 29 286 1.01E-100 T 29-03-2018 A616_RS14960 16dcb8c2c0a6d153f0c79f02d25281f5 286 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 23 286 1.2E-124 T 29-03-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 A616_RS14960 16dcb8c2c0a6d153f0c79f02d25281f5 286 Pfam PF03301 Tryptophan 2,3-dioxygenase 19 212 1.4E-44 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 A616_RS04350 e2654b7145aaa885c0e9b8bc328deeb3 291 Pfam PF13394 4Fe-4S single cluster domain 12 90 5.4E-5 T 29-03-2018 A616_RS04350 e2654b7145aaa885c0e9b8bc328deeb3 291 SUPERFAMILY SSF102114 6 286 9.55E-37 T 29-03-2018 A616_RS04350 e2654b7145aaa885c0e9b8bc328deeb3 291 Pfam PF04055 Radical SAM superfamily 9 152 8.1E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS04350 e2654b7145aaa885c0e9b8bc328deeb3 291 Pfam PF13186 Iron-sulfur cluster-binding domain 218 283 1.6E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain A616_RS04350 e2654b7145aaa885c0e9b8bc328deeb3 291 Gene3D G3DSA:3.20.20.70 159 288 0.013 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS04350 e2654b7145aaa885c0e9b8bc328deeb3 291 Gene3D G3DSA:3.20.20.70 2 158 6.5E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 SUPERFAMILY SSF53092 5 177 3.66E-32 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 Pfam PF05195 Aminopeptidase P, N-terminal domain 10 126 1.4E-27 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 PRINTS PR00599 Methionine aminopeptidase-1 signature 256 272 6.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 PRINTS PR00599 Methionine aminopeptidase-1 signature 362 374 6.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 PRINTS PR00599 Methionine aminopeptidase-1 signature 234 247 6.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 Gene3D G3DSA:3.40.350.10 1 181 1.1E-35 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 Pfam PF00557 Metallopeptidase family M24 183 395 1.1E-56 T 29-03-2018 IPR000994 Peptidase M24 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 SMART SM01011 5 142 8.3E-35 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 Gene3D G3DSA:3.90.230.10 182 420 9.7E-74 T 29-03-2018 A616_RS15875 c1ff48557f35136f0dedef7914d4410c 420 SUPERFAMILY SSF55920 178 416 9.81E-72 T 29-03-2018 IPR000994 Peptidase M24 A616_RS24535 9e4b0ffc2b3ac8d6f1572c3db62dd956 381 SUPERFAMILY SSF141571 220 358 6.08E-29 T 29-03-2018 A616_RS24535 9e4b0ffc2b3ac8d6f1572c3db62dd956 381 Pfam PF00805 Pentapeptide repeats (8 copies) 318 355 2.5E-13 T 29-03-2018 IPR001646 Pentapeptide repeat A616_RS24535 9e4b0ffc2b3ac8d6f1572c3db62dd956 381 Gene3D G3DSA:2.160.10.20 210 283 5.0E-13 T 29-03-2018 A616_RS24535 9e4b0ffc2b3ac8d6f1572c3db62dd956 381 Gene3D G3DSA:2.160.10.20 312 373 6.4E-14 T 29-03-2018 A616_RS24535 9e4b0ffc2b3ac8d6f1572c3db62dd956 381 Pfam PF13599 Pentapeptide repeats (9 copies) 229 291 1.5E-6 T 29-03-2018 IPR001646 Pentapeptide repeat A616_RS24535 9e4b0ffc2b3ac8d6f1572c3db62dd956 381 Gene3D G3DSA:3.30.1120.50 284 311 0.012 T 29-03-2018 A616_RS21940 5f197330a33e64976b2adad6de0de6ea 110 Gene3D G3DSA:1.10.10.10 2 100 1.2E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21940 5f197330a33e64976b2adad6de0de6ea 110 SUPERFAMILY SSF46785 6 102 1.78E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21940 5f197330a33e64976b2adad6de0de6ea 110 Pfam PF03551 Transcriptional regulator PadR-like family 19 91 2.1E-21 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 SMART SM00448 10 123 1.6E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 9.0E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 SUPERFAMILY SSF46894 160 227 8.16E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 Pfam PF00072 Response regulator receiver domain 12 123 7.4E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 SMART SM00421 164 221 2.3E-27 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 Gene3D G3DSA:1.10.10.10 133 228 2.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 Gene3D G3DSA:3.40.50.2300 1 132 7.3E-33 T 29-03-2018 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 3.4E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 3.4E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 3.4E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 SUPERFAMILY SSF52172 10 134 5.83E-34 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS18625 e43d5167bcf84bdbca15cc3b5724e465 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 172 5.2E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 Gene3D G3DSA:1.10.10.10 94 175 3.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 Gene3D G3DSA:1.10.1740.10 1 93 2.2E-21 T 29-03-2018 A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 SUPERFAMILY SSF88659 108 173 1.16E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 Pfam PF08281 Sigma-70, region 4 116 167 1.1E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 SUPERFAMILY SSF88946 2 106 5.02E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30660 15a325a9e5a01056cf724962fa7e9b35 190 Pfam PF04542 Sigma-70 region 2 21 89 1.8E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31345 3b7e4c88ee9f89d10260f3a19161fd6a 188 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 13 183 2.3E-57 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS31345 3b7e4c88ee9f89d10260f3a19161fd6a 188 SUPERFAMILY SSF110391 14 184 1.24E-47 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS31345 3b7e4c88ee9f89d10260f3a19161fd6a 188 PIRSF PIRSF016897 1 187 2.5E-58 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS31345 3b7e4c88ee9f89d10260f3a19161fd6a 188 Gene3D G3DSA:3.20.20.400 3 184 2.6E-61 T 29-03-2018 A616_RS30500 473b4dbf17a07a42159d73452249bd15 199 Gene3D G3DSA:3.20.20.400 6 188 8.9E-62 T 29-03-2018 A616_RS30500 473b4dbf17a07a42159d73452249bd15 199 PIRSF PIRSF016897 4 192 8.9E-57 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS30500 473b4dbf17a07a42159d73452249bd15 199 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 16 187 3.9E-57 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS30500 473b4dbf17a07a42159d73452249bd15 199 SUPERFAMILY SSF110391 15 188 1.09E-48 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 SUPERFAMILY SSF51971 337 521 1.41E-40 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 Gene3D G3DSA:3.20.20.70 2 373 5.7E-112 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 481 8.5E-14 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 614 630 8.5E-14 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 503 521 8.5E-14 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 400 8.5E-14 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 SUPERFAMILY SSF51905 553 644 1.05E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 SUPERFAMILY SSF51905 466 524 1.05E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 379 630 2.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 Gene3D G3DSA:3.40.50.720 374 481 1.2E-22 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 SUPERFAMILY SSF51395 3 366 3.38E-113 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 334 5.2E-79 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 380 402 4.9E-5 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 615 629 4.9E-5 T 29-03-2018 A616_RS22410 224a96ed32bb25ade432978cd34144fe 667 Gene3D G3DSA:3.50.50.60 482 635 1.7E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS17745 6bf1128d38ab53e1faa4133904c54e27 247 SUPERFAMILY SSF142823 18 241 1.44E-43 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A616_RS17745 6bf1128d38ab53e1faa4133904c54e27 247 Gene3D G3DSA:3.90.1560.10 23 247 8.2E-62 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A616_RS17745 6bf1128d38ab53e1faa4133904c54e27 247 Pfam PF04029 2-phosphosulpholactate phosphatase 32 240 1.9E-27 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 Gene3D G3DSA:1.10.150.240 17 95 3.1E-7 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 Gene3D G3DSA:3.40.50.1000 96 234 1.6E-29 T 29-03-2018 IPR023214 HAD-like domain A616_RS05335 91f339c457ca6d089463a50596380cb3 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 207 7.9E-24 T 29-03-2018 IPR023214 HAD-like domain A616_RS05335 91f339c457ca6d089463a50596380cb3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 117 130 4.1E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 4.1E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 4.1E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 120 201 4.6E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 78 207 3.8E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05335 91f339c457ca6d089463a50596380cb3 234 SUPERFAMILY SSF56784 3 233 1.57E-44 T 29-03-2018 IPR023214 HAD-like domain A616_RS26785 b376ab050693b519a30c03783a73315c 527 PIRSF PIRSF006294 1 526 6.0E-241 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A616_RS26785 b376ab050693b519a30c03783a73315c 527 Pfam PF01293 Phosphoenolpyruvate carboxykinase 17 480 3.3E-226 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A616_RS26785 b376ab050693b519a30c03783a73315c 527 Gene3D G3DSA:3.90.228.20 212 290 3.9E-29 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A616_RS26785 b376ab050693b519a30c03783a73315c 527 Gene3D G3DSA:3.90.228.20 291 524 2.0E-96 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A616_RS26785 b376ab050693b519a30c03783a73315c 527 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 11 524 55.588 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A616_RS26785 b376ab050693b519a30c03783a73315c 527 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 7 526 1.3E-237 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A616_RS26785 b376ab050693b519a30c03783a73315c 527 SUPERFAMILY SSF68923 11 211 8.89E-83 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A616_RS26785 b376ab050693b519a30c03783a73315c 527 SUPERFAMILY SSF53795 212 525 1.68E-135 T 29-03-2018 A616_RS26785 b376ab050693b519a30c03783a73315c 527 Gene3D G3DSA:3.40.449.10 18 210 4.3E-80 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A616_RS26785 b376ab050693b519a30c03783a73315c 527 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 249 264 - T 29-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A616_RS25965 fa7667fec32c085b4500f146f061573f 321 SUPERFAMILY SSF53613 1 317 1.48E-88 T 29-03-2018 IPR029056 Ribokinase-like A616_RS25965 fa7667fec32c085b4500f146f061573f 321 Pfam PF00294 pfkB family carbohydrate kinase 3 309 2.6E-73 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB A616_RS25965 fa7667fec32c085b4500f146f061573f 321 PRINTS PR00990 Ribokinase signature 28 47 2.5E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS25965 fa7667fec32c085b4500f146f061573f 321 PRINTS PR00990 Ribokinase signature 223 234 2.5E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS25965 fa7667fec32c085b4500f146f061573f 321 PRINTS PR00990 Ribokinase signature 183 198 2.5E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS25965 fa7667fec32c085b4500f146f061573f 321 Gene3D G3DSA:3.40.1190.20 2 321 1.6E-78 T 29-03-2018 IPR029056 Ribokinase-like A616_RS25965 fa7667fec32c085b4500f146f061573f 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 SUPERFAMILY SSF52540 5 254 9.38E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 Pfam PF00005 ABC transporter 32 182 6.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 Gene3D G3DSA:3.40.50.300 2 322 9.3E-88 T 29-03-2018 A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 319 8.3E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 3.5E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS08825 2d339cf46b75a163b4a17c34bb9385bf 322 SMART SM00382 40 232 1.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 324 36.22 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Pfam PF03099 Biotin/lipoate A/B protein ligase family 103 212 2.1E-16 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 84 322 6.0E-66 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Pfam PF02237 Biotin protein ligase C terminal domain 277 321 9.3E-6 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Gene3D G3DSA:3.30.930.10 64 276 5.5E-64 T 29-03-2018 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 SUPERFAMILY SSF46785 6 60 7.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 SUPERFAMILY SSF50037 280 324 3.11E-6 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Gene3D G3DSA:2.30.30.100 278 321 4.6E-10 T 29-03-2018 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 SUPERFAMILY SSF55681 70 275 5.84E-58 T 29-03-2018 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Pfam PF08279 HTH domain 6 58 8.1E-14 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS13945 164ab2ebbe83ed0166953a86944e3789 327 Gene3D G3DSA:1.10.10.10 2 63 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 SUPERFAMILY SSF51905 434 484 2.06E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 SUPERFAMILY SSF51905 3 180 2.06E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 SUPERFAMILY SSF51905 224 251 2.06E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 Pfam PF12831 FAD dependent oxidoreductase 7 507 1.9E-111 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 260 2.7E-8 T 29-03-2018 A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.7E-8 T 29-03-2018 A616_RS21980 97b47e5c48dde4bceea8cf35040f81f6 524 Gene3D G3DSA:3.50.50.60 2 379 3.6E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS18785 463393a18e15184e22d07975c9509390 800 SUPERFAMILY SSF52540 252 486 2.94E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 567 582 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 670 687 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 687 706 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 605 619 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 745 757 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 619 638 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 527 541 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 PRINTS PR00819 CbxX/CfqX superfamily signature 649 661 2.0E-44 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 SUPERFAMILY SSF52540 519 772 2.72E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18785 463393a18e15184e22d07975c9509390 800 SMART SM00382 564 702 4.8E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS18785 463393a18e15184e22d07975c9509390 800 SMART SM00382 289 470 1.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS18785 463393a18e15184e22d07975c9509390 800 Gene3D G3DSA:1.10.8.60 694 777 0.026 T 29-03-2018 A616_RS18785 463393a18e15184e22d07975c9509390 800 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 294 404 3.4E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 569 698 1.6E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS18785 463393a18e15184e22d07975c9509390 800 Gene3D G3DSA:3.40.50.300 213 427 3.8E-27 T 29-03-2018 A616_RS18785 463393a18e15184e22d07975c9509390 800 Gene3D G3DSA:3.40.50.300 515 693 3.0E-23 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 SUPERFAMILY SSF53067 2 158 1.78E-48 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 30 42 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 173 183 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 2 15 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 113 133 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 352 371 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 441 457 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 296 312 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 PRINTS PR00301 70kDa heat shock protein signature 327 347 5.6E-43 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 SUPERFAMILY SSF100920 350 510 1.09E-38 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 167 180 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Pfam PF00012 Hsp70 protein 4 75 4.5E-16 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Pfam PF00012 Hsp70 protein 81 556 2.4E-117 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 SUPERFAMILY SSF53067 162 343 4.71E-46 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Gene3D G3DSA:3.30.420.40 1 169 3.2E-55 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Gene3D G3DSA:3.90.640.10 211 265 1.6E-6 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 6 13 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Gene3D G3DSA:3.30.420.40 266 324 9.0E-13 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Gene3D G3DSA:3.30.420.40 170 210 1.2E-13 T 29-03-2018 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 299 313 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A616_RS10905 8ba3e570b492f9d4b750894b9bea1dab 566 Gene3D G3DSA:2.60.34.10 333 556 1.7E-45 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 Gene3D G3DSA:3.40.190.10 177 261 1.9E-19 T 29-03-2018 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 Pfam PF03466 LysR substrate binding domain 89 287 4.6E-39 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 Gene3D G3DSA:3.40.190.10 90 176 3.4E-19 T 29-03-2018 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 SUPERFAMILY SSF53850 91 290 9.31E-41 T 29-03-2018 A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 SUPERFAMILY SSF46785 1 85 2.72E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05740 9085bc11d834a58cf49d2e1febced044 293 Gene3D G3DSA:1.10.10.10 1 83 1.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.40.50.150 1038 1328 2.2E-19 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF56801 1392 1471 9.03E-176 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF56801 479 978 9.03E-176 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.30.300.30 1329 1463 2.1E-19 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Pfam PF00501 AMP-binding enzyme 524 922 5.3E-112 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Pfam PF13847 Methyltransferase domain 1045 1176 3.2E-11 T 29-03-2018 IPR025714 Methyltransferase domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:2.30.38.10 831 912 5.0E-27 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF52777 56 233 1.78E-51 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.40.50.980 671 830 5.8E-41 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 544 946 2.6E-146 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:1.10.1200.10 1464 1535 7.8E-20 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SMART SM00823 Phosphopantetheine attachment site 1458 1526 7.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF52777 241 508 1.06E-63 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Pfam PF00668 Condensation domain 1558 1994 3.7E-70 T 29-03-2018 IPR001242 Condensation domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Pfam PF00668 Condensation domain 51 502 1.7E-119 T 29-03-2018 IPR001242 Condensation domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF47336 1451 1522 2.36E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.30.559.10 1536 1764 5.5E-27 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.30.559.10 44 259 5.8E-49 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF52777 1563 1741 1.78E-35 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.40.50.980 513 670 3.2E-51 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Gene3D G3DSA:3.30.300.30 916 1037 6.1E-16 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 ProSitePatterns PS00455 Putative AMP-binding domain signature. 665 676 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF52777 1742 1996 2.33E-45 T 29-03-2018 A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 Pfam PF00550 Phosphopantetheine attachment site 1461 1521 6.3E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1482 1497 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS22025 61ccdb3cafbc7bc4b2f4e190647ffd91 2004 SUPERFAMILY SSF53335 1014 1206 2.52E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 Gene3D G3DSA:3.20.20.70 102 353 7.6E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 SUPERFAMILY SSF51569 32 352 6.69E-98 T 29-03-2018 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 350 2.9E-119 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 Pfam PF01817 Chorismate mutase type II 10 86 4.4E-20 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 101 7.7E-40 T 29-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 Pfam PF00793 DAHP synthetase I family 111 346 1.5E-79 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 SMART SM00830 10 89 1.2E-23 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS22990 535da30e99586a2fed74e7dbacf13196 365 Gene3D G3DSA:1.20.59.10 1 101 9.6E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS24775 d3b1caa8cbd3c83826d99dedc59b677b 402 Gene3D G3DSA:1.20.1250.20 5 199 4.8E-33 T 29-03-2018 A616_RS24775 d3b1caa8cbd3c83826d99dedc59b677b 402 Pfam PF07690 Major Facilitator Superfamily 248 397 2.8E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24775 d3b1caa8cbd3c83826d99dedc59b677b 402 Pfam PF07690 Major Facilitator Superfamily 19 244 4.5E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24775 d3b1caa8cbd3c83826d99dedc59b677b 402 Gene3D G3DSA:1.20.1250.20 207 402 4.8E-24 T 29-03-2018 A616_RS24775 d3b1caa8cbd3c83826d99dedc59b677b 402 SUPERFAMILY SSF103473 9 393 7.19E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 SUPERFAMILY SSF55874 314 463 9.43E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 Gene3D G3DSA:1.10.287.130 236 307 2.8E-14 T 29-03-2018 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 SMART SM00304 186 238 6.1E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 Gene3D G3DSA:3.30.565.10 314 465 3.4E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 SUPERFAMILY SSF47384 229 312 7.85E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 SMART SM00388 246 312 4.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 SMART SM00387 354 465 2.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 310 1.7E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 463 3.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 Pfam PF00672 HAMP domain 190 234 1.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05515 01920e866c9a2e6aa07da3b58f4f3e84 465 SUPERFAMILY SSF158472 188 237 1.83E-10 T 29-03-2018 A616_RS16280 e7f3f254a6987789dee7eb378c47796d 104 SUPERFAMILY SSF103481 6 102 9.55E-16 T 29-03-2018 A616_RS16280 e7f3f254a6987789dee7eb378c47796d 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.4E-22 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS08630 ba4ff73b66d1865ab4b59a626adcc764 245 Pfam PF08241 Methyltransferase domain 47 141 1.1E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS08630 ba4ff73b66d1865ab4b59a626adcc764 245 SUPERFAMILY SSF53335 3 218 1.18E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS08630 ba4ff73b66d1865ab4b59a626adcc764 245 Gene3D G3DSA:3.40.50.150 25 242 1.2E-39 T 29-03-2018 A616_RS12045 1255df20d3afac6bdbd9423c0034b431 141 SUPERFAMILY SSF54593 6 124 4.56E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS12045 1255df20d3afac6bdbd9423c0034b431 141 Gene3D G3DSA:3.10.180.10 1 135 2.0E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS12045 1255df20d3afac6bdbd9423c0034b431 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 122 4.0E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS20930 624a55a60e59109e51cc8ca64e349691 207 Gene3D G3DSA:3.50.30.50 1 203 3.1E-49 T 29-03-2018 A616_RS20930 624a55a60e59109e51cc8ca64e349691 207 SUPERFAMILY SSF102198 1 201 7.32E-53 T 29-03-2018 A616_RS20930 624a55a60e59109e51cc8ca64e349691 207 Pfam PF04199 Putative cyclase 4 146 3.0E-23 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 SUPERFAMILY SSF46785 174 239 1.65E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 SMART SM00448 8 121 4.8E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 PIRSF PIRSF006171 6 238 2.7E-79 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 Pfam PF09339 IclR helix-turn-helix domain 176 218 1.7E-5 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 Gene3D G3DSA:3.40.50.2300 7 149 2.0E-31 T 29-03-2018 A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 Gene3D G3DSA:1.10.10.10 168 246 1.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 Pfam PF00072 Response regulator receiver domain 10 121 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07450 b3d997b1f3a2063ceaf7009e5fab3711 253 SUPERFAMILY SSF52172 6 133 1.14E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23095 61a340f8fa4a71542875d370c63a3003 160 Gene3D G3DSA:3.30.70.640 3 158 9.3E-69 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A616_RS23095 61a340f8fa4a71542875d370c63a3003 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 5 152 8.4E-67 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A616_RS23095 61a340f8fa4a71542875d370c63a3003 160 SUPERFAMILY SSF55040 13 155 4.32E-59 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A616_RS23095 61a340f8fa4a71542875d370c63a3003 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 3 158 36.667 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A616_RS23095 61a340f8fa4a71542875d370c63a3003 160 Pfam PF01967 MoaC family 16 150 2.0E-55 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A616_RS20800 4f88df658644b9c3c07ff9509d737ad2 68 SUPERFAMILY SSF63562 1 65 6.63E-19 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A616_RS20800 4f88df658644b9c3c07ff9509d737ad2 68 Pfam PF01192 RNA polymerase Rpb6 8 54 3.0E-11 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A616_RS20800 4f88df658644b9c3c07ff9509d737ad2 68 SMART SM01409 8 61 1.5E-10 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A616_RS20800 4f88df658644b9c3c07ff9509d737ad2 68 Gene3D G3DSA:3.90.940.10 1 65 3.3E-18 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A616_RS20800 4f88df658644b9c3c07ff9509d737ad2 68 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 14.194 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS20800 4f88df658644b9c3c07ff9509d737ad2 68 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 54 2.6E-14 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Gene3D G3DSA:3.40.50.300 86 267 2.1E-25 T 29-03-2018 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 531 549 2.7E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 502 520 2.7E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 457 475 2.7E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 564 578 2.7E-36 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Gene3D G3DSA:1.10.8.60 268 403 1.7E-35 T 29-03-2018 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 SUPERFAMILY SSF52540 402 697 1.05E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 SMART SM01086 622 709 3.7E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 SUPERFAMILY SSF52540 88 402 5.74E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Gene3D G3DSA:3.40.50.300 408 621 1.3E-48 T 29-03-2018 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Pfam PF02151 UvrB/uvrC motif 340 371 4.3E-5 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 220 232 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Gene3D G3DSA:1.10.8.60 622 712 4.3E-21 T 29-03-2018 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 SMART SM00382 125 267 1.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 SMART SM00382 453 623 8.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 622 693 1.6E-21 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Pfam PF07724 AAA domain (Cdc48 subfamily) 452 616 2.2E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 130 249 7.4E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS24385 0af1f211eaaed4857f04c496c46a90f2 712 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 487 505 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 SUPERFAMILY SSF48557 3 427 6.28E-143 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 Gene3D G3DSA:1.20.200.10 93 348 8.9E-83 T 29-03-2018 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 2.2E-27 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 Pfam PF00206 Lyase 7 286 4.8E-76 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 2.9E-182 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.2E-28 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 Gene3D G3DSA:1.10.275.10 2 92 1.6E-26 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 Gene3D G3DSA:1.10.40.30 349 428 8.2E-28 T 29-03-2018 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 SMART SM00998 349 429 9.3E-41 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.1E-11 T 29-03-2018 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.1E-11 T 29-03-2018 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.1E-11 T 29-03-2018 A616_RS03215 1e5e8a7ad455c759e55dde103f79e745 431 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 1.1E-11 T 29-03-2018 A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 Pfam PF01433 Peptidase family M1 domain 326 472 3.9E-9 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 Pfam PF07833 Copper amine oxidase N-terminal domain 518 609 6.0E-19 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 Gene3D G3DSA:3.30.457.10 590 616 0.0096 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 Gene3D G3DSA:3.30.457.10 521 589 1.2E-14 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 SUPERFAMILY SSF55486 277 481 2.12E-19 T 29-03-2018 A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 SUPERFAMILY SSF55383 521 603 1.16E-15 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 Gene3D G3DSA:2.60.40.1730 67 249 4.4E-7 T 29-03-2018 A616_RS12890 2bf7dabb16f9743b4bb71751bd38f340 622 Gene3D G3DSA:1.10.390.10 327 485 2.1E-14 T 29-03-2018 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Pfam PF00989 PAS fold 15 86 1.6E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Gene3D G3DSA:3.30.450.20 131 256 9.7E-13 T 29-03-2018 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Pfam PF13426 PAS domain 146 245 1.2E-9 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Gene3D G3DSA:1.10.287.130 257 326 1.2E-13 T 29-03-2018 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 264 327 9.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 253 2.0E-7 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 102 2.3E-10 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SUPERFAMILY SSF55785 135 239 7.03E-10 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SUPERFAMILY SSF55785 11 108 1.11E-11 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Gene3D G3DSA:3.30.565.10 330 477 5.5E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SMART SM00388 262 330 4.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SUPERFAMILY SSF47384 254 327 1.71E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 476 8.0E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SMART SM00091 14 81 6.7E-6 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SMART SM00091 135 201 0.085 T 29-03-2018 IPR000014 PAS domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 439 2.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 2.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 2.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 425 2.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 Gene3D G3DSA:3.30.450.20 7 120 8.3E-13 T 29-03-2018 A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SMART SM00387 372 477 1.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00505 57ab8519fe48c3f8dcd9d57d8073bc63 477 SUPERFAMILY SSF55874 321 477 3.14E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07645 b55e59e5b5fc7201964c59d41c886352 315 Pfam PF01636 Phosphotransferase enzyme family 19 256 4.0E-23 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS07645 b55e59e5b5fc7201964c59d41c886352 315 SUPERFAMILY SSF56112 3 275 6.41E-29 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS07645 b55e59e5b5fc7201964c59d41c886352 315 Gene3D G3DSA:3.90.1200.10 101 313 3.8E-19 T 29-03-2018 A616_RS07645 b55e59e5b5fc7201964c59d41c886352 315 Gene3D G3DSA:3.30.200.20 1 100 5.5E-12 T 29-03-2018 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 SUPERFAMILY SSF88946 5 98 1.88E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 Gene3D G3DSA:1.10.1740.10 2 102 8.5E-30 T 29-03-2018 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 185 6.8E-80 T 29-03-2018 IPR014294 RNA polymerase sigma-W, bacillaceae A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 Pfam PF04542 Sigma-70 region 2 23 89 1.6E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 Gene3D G3DSA:1.10.10.10 107 186 6.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 SUPERFAMILY SSF88659 116 184 1.36E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 184 3.4E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01695 37f6f3a6b4dec5aeb10d0962a49ae81a 187 Pfam PF08281 Sigma-70, region 4 129 180 1.1E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 25 264 1.6E-29 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 SUPERFAMILY SSF53335 22 338 5.81E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 Pfam PF00145 C-5 cytosine-specific DNA methylase 22 339 2.8E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 Gene3D G3DSA:3.40.50.150 21 278 2.5E-41 T 29-03-2018 A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 188 201 9.2E-10 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 22 38 9.2E-10 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS06320 64dba5df4497f8f8ab074a9927894c34 347 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 142 156 9.2E-10 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 PIRSF PIRSF002599 1 67 2.2E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 PRINTS PR00050 Cold shock protein signature 25 34 3.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 PRINTS PR00050 Cold shock protein signature 40 58 3.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 PRINTS PR00050 Cold shock protein signature 5 20 3.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 8.2E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 SUPERFAMILY SSF50249 3 66 5.83E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS17760 92179ad79f394fae0459c6f13a962186 67 SMART SM00357 4 67 4.6E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 Gene3D G3DSA:2.40.50.140 2 67 3.9E-27 T 29-03-2018 A616_RS17760 92179ad79f394fae0459c6f13a962186 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 29-03-2018 IPR019844 Cold-shock conserved site A616_RS14200 a2cd3c405d2d0b5eae6bbb3f207f1e07 408 Gene3D G3DSA:3.30.9.10 104 344 7.1E-21 T 29-03-2018 A616_RS14200 a2cd3c405d2d0b5eae6bbb3f207f1e07 408 SUPERFAMILY SSF51905 345 398 2.85E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14200 a2cd3c405d2d0b5eae6bbb3f207f1e07 408 SUPERFAMILY SSF51905 28 253 2.85E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14200 a2cd3c405d2d0b5eae6bbb3f207f1e07 408 Pfam PF01266 FAD dependent oxidoreductase 30 384 1.2E-45 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS14200 a2cd3c405d2d0b5eae6bbb3f207f1e07 408 Gene3D G3DSA:3.50.50.60 27 103 1.8E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 Pfam PF00072 Response regulator receiver domain 401 513 4.6E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 SMART SM00421 553 610 5.5E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 Pfam PF00196 Bacterial regulatory proteins, luxR family 556 609 1.4E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 SMART SM00387 302 392 1.7E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 SMART SM00448 399 512 5.2E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 SUPERFAMILY SSF52172 398 530 4.98E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 Gene3D G3DSA:3.30.565.10 265 396 4.6E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 556 570 3.1E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 570 586 3.1E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 586 598 3.1E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 SUPERFAMILY SSF55874 272 389 7.33E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 Gene3D G3DSA:3.40.50.2300 398 523 1.1E-35 T 29-03-2018 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 Gene3D G3DSA:1.10.10.10 524 617 3.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 Pfam PF07730 Histidine kinase 199 256 9.6E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS31680 1c706e452a1d7a0b664fafc78a5b1458 617 SUPERFAMILY SSF46894 549 615 1.56E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 SUPERFAMILY SSF46689 294 343 8.06E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 Gene3D G3DSA:1.10.10.60 232 300 2.0E-10 T 29-03-2018 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 SUPERFAMILY SSF46689 249 292 8.15E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 SMART SM00342 258 341 3.0E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 295 337 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 Pfam PF12833 Helix-turn-helix domain 267 342 9.1E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 Gene3D G3DSA:2.60.120.280 68 231 2.5E-4 T 29-03-2018 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 Gene3D G3DSA:1.10.10.60 301 349 1.1E-12 T 29-03-2018 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 325 5.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS15720 5b037fab096612ac48584cc7acd6e8f3 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 325 341 5.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS21270 0f27719eae7a2a4a2618a96beab73643 248 Pfam PF05949 Bacterial protein of unknown function (DUF881) 88 240 1.3E-33 T 29-03-2018 IPR010273 Protein of unknown function DUF881 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 Gene3D G3DSA:1.10.730.10 628 811 4.2E-40 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 SUPERFAMILY SSF52374 11 197 8.88E-134 T 29-03-2018 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 SUPERFAMILY SSF52374 383 635 8.88E-134 T 29-03-2018 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 547 556 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 381 396 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 507 520 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 219 242 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 SUPERFAMILY SSF47323 943 1014 6.98E-5 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 SUPERFAMILY SSF47323 643 876 5.79E-51 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 Gene3D G3DSA:3.40.50.620 2 627 3.8E-139 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 Pfam PF08264 Anticodon-binding domain of tRNA 674 819 5.6E-33 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 618 3.9E-189 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1015 13.568 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 SUPERFAMILY SSF50677 200 383 5.86E-50 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A616_RS24735 d6a967cb3f63f0d74827998330a46170 1026 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 6 823 5.4E-291 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS30085 cc1ad53570e1786bf1da3ffead95aef6 320 PIRSF PIRSF004532 1 319 1.7E-148 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A616_RS30085 cc1ad53570e1786bf1da3ffead95aef6 320 Gene3D G3DSA:3.30.540.10 154 319 2.1E-60 T 29-03-2018 A616_RS30085 cc1ad53570e1786bf1da3ffead95aef6 320 Gene3D G3DSA:3.30.540.10 1 153 6.7E-54 T 29-03-2018 A616_RS30085 cc1ad53570e1786bf1da3ffead95aef6 320 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 317 1.9E-140 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A616_RS30085 cc1ad53570e1786bf1da3ffead95aef6 320 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 310 3.3E-144 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A616_RS30085 cc1ad53570e1786bf1da3ffead95aef6 320 SUPERFAMILY SSF56655 1 313 3.8E-110 T 29-03-2018 A616_RS30070 1fc624243a18243262977e1a58f62f89 421 SUPERFAMILY SSF102114 179 385 4.45E-18 T 29-03-2018 A616_RS30070 1fc624243a18243262977e1a58f62f89 421 Gene3D G3DSA:3.20.20.70 176 400 1.2E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS30070 1fc624243a18243262977e1a58f62f89 421 Pfam PF04055 Radical SAM superfamily 181 351 2.2E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS08340 5c88784875436a277c8a84fe559c76f3 400 Pfam PF01548 Transposase 5 163 5.4E-34 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A616_RS08340 5c88784875436a277c8a84fe559c76f3 400 Gene3D G3DSA:1.10.150.20 288 369 0.0024 T 29-03-2018 A616_RS08340 5c88784875436a277c8a84fe559c76f3 400 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 361 8.0E-28 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A616_RS08340 5c88784875436a277c8a84fe559c76f3 400 Gene3D G3DSA:1.10.150.20 174 287 0.0051 T 29-03-2018 A616_RS15945 df11f0d9d975141f665da6f7774c4ea6 887 Gene3D G3DSA:2.60.40.10 415 494 1.2E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS15945 df11f0d9d975141f665da6f7774c4ea6 887 SUPERFAMILY SSF81296 417 494 3.27E-10 T 29-03-2018 IPR014756 Immunoglobulin E-set A616_RS15945 df11f0d9d975141f665da6f7774c4ea6 887 Pfam PF01833 IPT/TIG domain 417 485 2.5E-5 T 29-03-2018 IPR002909 IPT domain A616_RS15945 df11f0d9d975141f665da6f7774c4ea6 887 Gene3D G3DSA:3.40.50.1110 588 887 8.7E-14 T 29-03-2018 A616_RS15945 df11f0d9d975141f665da6f7774c4ea6 887 Gene3D G3DSA:2.60.40.10 495 585 5.2E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS15945 df11f0d9d975141f665da6f7774c4ea6 887 SUPERFAMILY SSF52266 590 887 2.22E-8 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS30495 c554733682334944defb46a08c29115d 220 SUPERFAMILY SSF56784 2 204 6.57E-49 T 29-03-2018 IPR023214 HAD-like domain A616_RS30495 c554733682334944defb46a08c29115d 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 2.6E-43 T 29-03-2018 IPR023214 HAD-like domain A616_RS30495 c554733682334944defb46a08c29115d 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 67 183 2.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS30495 c554733682334944defb46a08c29115d 220 Gene3D G3DSA:3.40.50.1000 1 212 6.7E-37 T 29-03-2018 IPR023214 HAD-like domain A616_RS30495 c554733682334944defb46a08c29115d 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS30495 c554733682334944defb46a08c29115d 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 1.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS30495 c554733682334944defb46a08c29115d 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 1.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS30495 c554733682334944defb46a08c29115d 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 178 1.4E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 Gene3D G3DSA:1.10.1660.10 63 136 8.6E-6 T 29-03-2018 A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 Gene3D G3DSA:3.20.80.10 137 258 4.0E-6 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 SMART SM00422 5 75 1.6E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 SUPERFAMILY SSF46955 4 111 9.89E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 SUPERFAMILY SSF55136 125 259 7.06E-6 T 29-03-2018 A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 Pfam PF13411 MerR HTH family regulatory protein 5 73 2.6E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17875 da9d33dcbbbe7cb898f76c72ab8cf047 267 Gene3D G3DSA:1.10.1660.10 1 62 2.9E-16 T 29-03-2018 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 SMART SM00864 13 205 5.0E-117 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 330 4.2E-137 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 Gene3D G3DSA:3.30.1330.20 215 323 1.3E-45 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 SUPERFAMILY SSF52490 12 208 1.57E-71 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 SUPERFAMILY SSF55307 204 319 7.1E-44 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 Pfam PF12327 FtsZ family, C-terminal domain 222 316 4.1E-33 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 Gene3D G3DSA:3.40.50.1440 8 214 3.0E-43 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 8.1E-41 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 363 39.127 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.1E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS21255 64036038e5e0c7aa9f403441b3ecde15 382 SMART SM00865 207 324 1.0E-54 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 Gene3D G3DSA:1.10.10.10 8 112 8.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 1.2E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.7E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.7E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.7E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 SMART SM00418 11 89 3.4E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS19125 23b4dd5fb9d8034c63eea1697fe8058b 114 SUPERFAMILY SSF46785 9 101 1.66E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04780 e66a4a14b87b3ec961093fa6d92ce8d2 209 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 198 1.3E-10 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 Gene3D G3DSA:3.40.50.620 1 158 1.1E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 60 2.0E-16 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.682 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 Pfam PF01467 Cytidylyltransferase-like 6 133 2.6E-19 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 SUPERFAMILY SSF52374 1 156 1.93E-43 T 29-03-2018 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 4.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 4.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 4.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 4.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 4.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 74 8.0E-4 T 29-03-2018 A616_RS20355 2f28f30658689f1be349dfa36f860dd5 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 5.3E-63 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A616_RS23410 fa2ab81f63aa94de2568234ab50715ae 238 Gene3D G3DSA:3.90.550.10 1 238 4.7E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS23410 fa2ab81f63aa94de2568234ab50715ae 238 Pfam PF12804 MobA-like NTP transferase domain 3 129 2.6E-10 T 29-03-2018 IPR025877 MobA-like NTP transferase A616_RS23410 fa2ab81f63aa94de2568234ab50715ae 238 SUPERFAMILY SSF53448 1 228 1.49E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31845 e35c0e0a5ac544e87f1f6c5ba55e82c5 724 Pfam PF00144 Beta-lactamase 397 684 1.7E-58 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS31845 e35c0e0a5ac544e87f1f6c5ba55e82c5 724 Pfam PF00144 Beta-lactamase 50 365 7.1E-53 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS31845 e35c0e0a5ac544e87f1f6c5ba55e82c5 724 SUPERFAMILY SSF56601 47 366 2.9E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS31845 e35c0e0a5ac544e87f1f6c5ba55e82c5 724 SUPERFAMILY SSF56601 391 711 2.29E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS31845 e35c0e0a5ac544e87f1f6c5ba55e82c5 724 Gene3D G3DSA:3.40.710.10 39 372 1.7E-69 T 29-03-2018 A616_RS31845 e35c0e0a5ac544e87f1f6c5ba55e82c5 724 Gene3D G3DSA:3.40.710.10 385 719 3.1E-75 T 29-03-2018 A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 Pfam PF01546 Peptidase family M20/M25/M40 88 420 2.4E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 23 414 2.1E-102 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 SUPERFAMILY SSF53187 340 424 6.57E-64 T 29-03-2018 A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 SUPERFAMILY SSF53187 9 200 6.57E-64 T 29-03-2018 A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 Gene3D G3DSA:3.40.630.10 10 198 4.5E-35 T 29-03-2018 A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 Pfam PF07687 Peptidase dimerisation domain 191 311 3.2E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 Gene3D G3DSA:3.30.70.360 199 328 8.0E-19 T 29-03-2018 A616_RS17995 db5be8c13849f5ae46a8d538e0fb74b6 431 SUPERFAMILY SSF55031 216 310 2.84E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 SUPERFAMILY SSF50249 9 102 7.59E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 Pfam PF01336 OB-fold nucleic acid binding domain 20 95 8.2E-13 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 423 1.5E-86 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 429 41.784 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 1.1E-16 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 1.1E-16 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 1.1E-16 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 1.1E-16 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 SUPERFAMILY SSF55681 110 424 3.73E-100 T 29-03-2018 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 Gene3D G3DSA:3.30.930.10 101 429 1.2E-97 T 29-03-2018 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 4 428 7.6E-158 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A616_RS14015 f91d64dfed7e4b714c3e17b6e1676cab 429 Gene3D G3DSA:2.40.50.140 11 100 1.3E-17 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 SMART SM00464 9 201 6.5E-81 T 29-03-2018 IPR003111 Lon, substrate-binding domain A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 SUPERFAMILY SSF88697 9 200 7.21E-50 T 29-03-2018 IPR015947 PUA-like domain A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 488 8.0E-24 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 PIRSF PIRSF001174 2 774 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 TIGRFAM TIGR00763 lon: endopeptidase La 11 770 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 SUPERFAMILY SSF52540 310 585 1.3E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 SUPERFAMILY SSF54211 594 770 5.31E-58 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Gene3D G3DSA:1.10.4060.10 120 210 2.3E-31 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Gene3D G3DSA:3.30.230.10 576 779 4.6E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 675 683 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 SMART SM00382 347 492 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 1.8E-55 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 1.8E-55 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 1.8E-55 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 594 610 1.8E-55 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 1.8E-55 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Gene3D G3DSA:1.10.8.60 491 575 3.1E-29 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Gene3D G3DSA:3.40.50.300 312 490 9.9E-33 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 9 200 7.7E-45 T 29-03-2018 IPR003111 Lon, substrate-binding domain A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Gene3D G3DSA:2.30.130.40 2 117 5.5E-29 T 29-03-2018 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 771 2.5E-100 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A616_RS10310 2ceb28ec862ddf6586c2462be12c4953 779 Hamap MF_01973 Lon protease [lon]. 10 771 71.522 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SUPERFAMILY SSF51126 1 117 7.52E-41 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SUPERFAMILY SSF51126 146 364 7.52E-41 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 Gene3D G3DSA:2.160.20.10 228 406 2.9E-16 T 29-03-2018 IPR012334 Pectin lyase fold A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 55 81 5300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 293 335 2500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 178 199 610.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 103 155 7300.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 249 270 3.5 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 271 292 5200.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 156 177 410.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 SMART SM00710 222 248 5500.0 T 29-03-2018 IPR006626 Parallel beta-helix repeat A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 Pfam PF05048 Periplasmic copper-binding protein (NosD) 145 358 1.8E-36 T 29-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 150 193 8.7E-9 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 243 284 6.2E-7 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 265 307 1.8E-7 T 29-03-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A616_RS07230 a9962c7ff0962db3fd537eab513fe3c7 430 Gene3D G3DSA:2.160.20.10 1 227 1.1E-26 T 29-03-2018 IPR012334 Pectin lyase fold A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 PIRSF PIRSF038800 4 418 1.1E-150 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 Gene3D G3DSA:3.90.1150.10 277 426 1.7E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 Pfam PF00266 Aminotransferase class-V 85 375 2.3E-22 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 TIGRFAM TIGR01814 kynureninase: kynureninase 12 411 2.2E-120 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 SUPERFAMILY SSF53383 10 412 1.79E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 Gene3D G3DSA:3.40.640.10 47 276 1.7E-23 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS09535 0b94bcdd9e6f4d775a84deb289a07fc8 426 Hamap MF_01970 Kynureninase [kynU]. 2 410 38.964 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.273 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Gene3D G3DSA:2.160.10.10 346 456 2.3E-22 T 29-03-2018 A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Gene3D G3DSA:2.160.10.10 241 345 4.1E-27 T 29-03-2018 A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 6.3E-8 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 9.6E-5 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 297 2.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Gene3D G3DSA:3.90.550.10 2 240 1.3E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 SUPERFAMILY SSF51161 223 437 4.45E-47 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 SUPERFAMILY SSF53448 5 253 2.92E-68 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 3.3E-179 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 Pfam PF12804 MobA-like NTP transferase domain 6 143 1.3E-24 T 29-03-2018 IPR025877 MobA-like NTP transferase A616_RS11920 8385ba003f7086e21bc7b84769667c8a 458 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 PIRSF PIRSF005962 1 373 3.0E-128 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 Pfam PF01546 Peptidase family M20/M25/M40 63 366 7.3E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 Pfam PF07687 Peptidase dimerisation domain 175 272 3.9E-12 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 SUPERFAMILY SSF53187 288 372 5.09E-81 T 29-03-2018 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 SUPERFAMILY SSF53187 2 187 5.09E-81 T 29-03-2018 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 SUPERFAMILY SSF55031 174 281 9.94E-34 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 5 356 3.2E-123 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 Gene3D G3DSA:3.40.630.10 262 373 5.1E-8 T 29-03-2018 A616_RS15060 a80a7a496dd43ad2d716780943b1dc75 373 Gene3D G3DSA:3.40.630.10 1 261 1.3E-66 T 29-03-2018 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 Pfam PF00155 Aminotransferase class I and II 128 474 6.1E-39 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 Gene3D G3DSA:3.90.1150.10 367 486 4.0E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 84 2.0E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 SMART SM00345 25 84 1.5E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 SUPERFAMILY SSF53383 113 483 1.95E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 Gene3D G3DSA:1.10.10.10 12 86 8.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 Gene3D G3DSA:3.40.640.10 160 366 3.6E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 SUPERFAMILY SSF46785 14 90 4.14E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 2.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS28495 78fa77aa0aced9783e036e7f95b0942e 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 2.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 SUPERFAMILY SSF56784 290 550 5.5E-42 T 29-03-2018 IPR023214 HAD-like domain A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 295 301 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 Gene3D G3DSA:1.20.1110.10 467 656 3.6E-33 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 293 307 1.9E-26 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 142 156 1.9E-26 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 537 1.9E-26 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 427 438 1.9E-26 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 449 459 1.9E-26 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 502 521 1.9E-26 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 2 660 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 63 588 6.2E-78 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 Pfam PF00702 haloacid dehalogenase-like hydrolase 289 516 1.7E-34 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 Gene3D G3DSA:2.70.150.10 20 196 5.5E-25 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 1 666 38.66 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 SUPERFAMILY SSF81653 100 193 6.8E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 SUPERFAMILY SSF81665 24 94 2.09E-8 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 SUPERFAMILY SSF81665 605 651 2.09E-8 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 SUPERFAMILY SSF81665 196 287 2.09E-8 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 Pfam PF00122 E1-E2 ATPase 94 271 1.1E-35 T 29-03-2018 A616_RS02255 51eefc1ee331753b19c5c581cc60c8da 666 Gene3D G3DSA:3.40.1110.10 300 466 3.8E-22 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A616_RS26760 c798341a4abb3ed0b71df9eb91f82304 465 SUPERFAMILY SSF101960 32 462 8.5E-139 T 29-03-2018 A616_RS26760 c798341a4abb3ed0b71df9eb91f82304 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 3.0E-227 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A616_RS26760 c798341a4abb3ed0b71df9eb91f82304 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 5.1E-72 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A616_RS09180 c588a54b58d59a4c7a823ffaa63b2369 306 Gene3D G3DSA:1.10.3720.10 3 293 9.5E-46 T 29-03-2018 A616_RS09180 c588a54b58d59a4c7a823ffaa63b2369 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 5.7E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09180 c588a54b58d59a4c7a823ffaa63b2369 306 SUPERFAMILY SSF161098 88 289 4.74E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07655 c7bbe508690b53d572d27a26d4f3eb78 232 SUPERFAMILY SSF53335 18 228 4.58E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS07655 c7bbe508690b53d572d27a26d4f3eb78 232 Gene3D G3DSA:3.40.50.150 5 232 4.0E-29 T 29-03-2018 A616_RS07655 c7bbe508690b53d572d27a26d4f3eb78 232 Pfam PF13649 Methyltransferase domain 49 146 6.1E-16 T 29-03-2018 A616_RS15815 8f6bcb84a4911717c991a1f8561e12ba 405 SUPERFAMILY SSF103473 19 391 1.18E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS15815 8f6bcb84a4911717c991a1f8561e12ba 405 Gene3D G3DSA:1.20.1250.20 204 403 1.1E-18 T 29-03-2018 A616_RS15815 8f6bcb84a4911717c991a1f8561e12ba 405 Gene3D G3DSA:1.20.1250.20 10 203 2.4E-31 T 29-03-2018 A616_RS15815 8f6bcb84a4911717c991a1f8561e12ba 405 Pfam PF07690 Major Facilitator Superfamily 25 336 1.2E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 Pfam PF00849 RNA pseudouridylate synthase 94 248 1.4E-34 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 19 307 6.7E-102 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 Gene3D G3DSA:3.10.290.10 7 78 1.1E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 SMART SM00363 21 80 2.7E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 SUPERFAMILY SSF55120 80 307 6.0E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 Gene3D G3DSA:3.30.2350.10 85 309 4.8E-75 T 29-03-2018 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 SUPERFAMILY SSF55174 21 107 7.74E-13 T 29-03-2018 A616_RS21040 360cedb23bd0993a59f50b9114f9028d 309 Pfam PF01479 S4 domain 21 67 3.6E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 Pfam PF00281 Ribosomal protein L5 26 81 3.1E-27 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 SUPERFAMILY SSF55282 4 180 1.11E-80 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 45.706 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 PIRSF PIRSF002161 1 180 6.4E-69 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 Gene3D G3DSA:3.30.1440.10 2 180 3.7E-82 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01460 498b675789fd82cd4b3134bd3f1948b4 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 9.3E-43 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS27205 932ed9e41f8845af50ce7402ce360933 328 Gene3D G3DSA:3.40.50.720 136 301 6.0E-33 T 29-03-2018 A616_RS27205 932ed9e41f8845af50ce7402ce360933 328 SUPERFAMILY SSF51735 1 328 7.58E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27205 932ed9e41f8845af50ce7402ce360933 328 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 3 319 1.1E-81 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS27205 932ed9e41f8845af50ce7402ce360933 328 Gene3D G3DSA:3.30.1780.10 1 135 1.7E-40 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A616_RS27205 932ed9e41f8845af50ce7402ce360933 328 PIRSF PIRSF001439 1 328 5.6E-93 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 Gene3D G3DSA:1.10.1040.10 173 292 1.0E-30 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 SUPERFAMILY SSF51735 4 163 1.43E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 PIRSF PIRSF000103 1 293 5.4E-70 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 Gene3D G3DSA:3.40.50.720 3 172 1.5E-30 T 29-03-2018 A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 2.0E-29 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 162 5.1E-39 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A616_RS18040 20340312af8ed4498280c261b2b3eb30 296 SUPERFAMILY SSF48179 163 288 1.93E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS26635 45e3f334cb5f593fd980174f827c912a 100 SUPERFAMILY SSF102891 1 99 5.1E-29 T 29-03-2018 IPR014931 Protein of unknown function DUF1805 A616_RS26635 45e3f334cb5f593fd980174f827c912a 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 2.1E-23 T 29-03-2018 IPR014931 Protein of unknown function DUF1805 A616_RS26635 45e3f334cb5f593fd980174f827c912a 100 Gene3D G3DSA:3.30.1980.10 1 99 1.1E-35 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF56784 331 351 1.86E-67 T 29-03-2018 IPR023214 HAD-like domain A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF56784 510 761 1.86E-67 T 29-03-2018 IPR023214 HAD-like domain A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF81665 234 327 1.96E-132 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF81665 707 906 1.96E-132 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF81665 8 120 1.96E-132 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 4.9E-41 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 693 4.9E-41 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 566 4.9E-41 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 676 4.9E-41 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 4.9E-41 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 587 4.9E-41 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SMART SM00831 8 82 7.8E-27 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Gene3D G3DSA:1.20.1110.10 590 927 8.3E-100 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Pfam PF00689 Cation transporting ATPase, C-terminus 741 907 8.3E-52 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 77 1.3E-19 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF81660 340 559 2.62E-56 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 335 341 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Gene3D G3DSA:2.70.150.10 17 234 3.1E-51 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 183 7.2E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 353 3.4E-30 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 625 747 1.3E-36 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Pfam PF00702 haloacid dehalogenase-like hydrolase 331 669 1.3E-23 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Pfam PF00122 E1-E2 ATPase 117 312 8.3E-56 T 29-03-2018 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 SUPERFAMILY SSF81653 119 233 8.76E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 657 673 3.9E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 629 645 3.9E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 513 531 3.9E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 689 714 3.9E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 Gene3D G3DSA:3.40.1110.10 296 562 2.0E-49 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A616_RS02345 4077134d4447412e6b1e7ce9685f51ed 934 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 59 899 1.0E-223 T 29-03-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 SUPERFAMILY SSF52540 537 711 5.98E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 Pfam PF00271 Helicase conserved C-terminal domain 567 668 3.8E-8 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 810 25.076 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 TIGRFAM TIGR00595 priA: primosomal protein N' 298 808 2.7E-214 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 SUPERFAMILY SSF52540 251 457 1.78E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 SMART SM00490 572 669 1.4E-8 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 Gene3D G3DSA:3.40.50.300 257 462 1.4E-26 T 29-03-2018 A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 SMART SM00487 270 469 5.6E-24 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 Pfam PF04851 Type III restriction enzyme, res subunit 274 436 9.4E-17 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A616_RS20790 ce7dbd3f898fe613ad3c73d5444f70dc 811 Gene3D G3DSA:3.40.50.300 469 710 1.6E-20 T 29-03-2018 A616_RS18405 344feeccd2fc2df10ab6437dd43fbb01 37 SUPERFAMILY SSF47413 1 35 9.12E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS18405 344feeccd2fc2df10ab6437dd43fbb01 37 Gene3D G3DSA:1.10.3100.10 1 36 5.8E-7 T 29-03-2018 IPR027910 YdiL-like domain A616_RS18405 344feeccd2fc2df10ab6437dd43fbb01 37 Pfam PF01381 Helix-turn-helix 2 35 3.2E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS29995 2f8bf656bcf23057a33c0507aa2cb198 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.573 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A616_RS29995 2f8bf656bcf23057a33c0507aa2cb198 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 2.7E-74 T 29-03-2018 A616_RS29995 2f8bf656bcf23057a33c0507aa2cb198 209 SUPERFAMILY SSF53271 4 207 3.07E-73 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS29995 2f8bf656bcf23057a33c0507aa2cb198 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 7.1E-91 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A616_RS29995 2f8bf656bcf23057a33c0507aa2cb198 209 Gene3D G3DSA:3.40.50.2020 2 207 7.0E-65 T 29-03-2018 A616_RS26495 cdbfe21a3806fa95c3e9a8bef81170f9 183 SUPERFAMILY SSF52317 1 182 2.81E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS26495 cdbfe21a3806fa95c3e9a8bef81170f9 183 Pfam PF01965 DJ-1/PfpI family 3 180 4.5E-38 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS26495 cdbfe21a3806fa95c3e9a8bef81170f9 183 Gene3D G3DSA:3.40.50.880 1 182 4.8E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS28690 3991067df08754c43bd82e4f90179677 594 Gene3D G3DSA:1.10.287.130 348 422 2.1E-17 T 29-03-2018 A616_RS28690 3991067df08754c43bd82e4f90179677 594 SMART SM00387 471 582 6.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28690 3991067df08754c43bd82e4f90179677 594 SUPERFAMILY SSF55874 416 578 1.7E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28690 3991067df08754c43bd82e4f90179677 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 1.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28690 3991067df08754c43bd82e4f90179677 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 1.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28690 3991067df08754c43bd82e4f90179677 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 1.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28690 3991067df08754c43bd82e4f90179677 594 SUPERFAMILY SSF47384 347 426 4.51E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28690 3991067df08754c43bd82e4f90179677 594 SMART SM00388 361 426 2.9E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28690 3991067df08754c43bd82e4f90179677 594 SMART SM00304 287 339 2.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS28690 3991067df08754c43bd82e4f90179677 594 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 579 4.7E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28690 3991067df08754c43bd82e4f90179677 594 Gene3D G3DSA:3.30.565.10 430 591 4.2E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28690 3991067df08754c43bd82e4f90179677 594 Pfam PF00672 HAMP domain 289 334 2.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS28690 3991067df08754c43bd82e4f90179677 594 SUPERFAMILY SSF158472 288 337 7.06E-8 T 29-03-2018 A616_RS28690 3991067df08754c43bd82e4f90179677 594 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 425 5.6E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Pfam PF02780 Transketolase, C-terminal domain 489 611 9.8E-31 T 29-03-2018 IPR033248 Transketolase, C-terminal domain A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Gene3D G3DSA:3.40.50.920 489 621 4.3E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 SUPERFAMILY SSF52518 310 498 5.89E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Pfam PF02779 Transketolase, pyrimidine binding domain 312 472 1.0E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS13150 66b389c9289e91b5b3000223f4704346 628 SMART SM00861 312 477 2.0E-63 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS13150 66b389c9289e91b5b3000223f4704346 628 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 619 2.9E-274 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 3.4E-124 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Gene3D G3DSA:3.40.50.970 1 293 6.2E-82 T 29-03-2018 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 SUPERFAMILY SSF52518 239 374 3.87E-79 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS13150 66b389c9289e91b5b3000223f4704346 628 SUPERFAMILY SSF52518 4 191 3.87E-79 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS13150 66b389c9289e91b5b3000223f4704346 628 SUPERFAMILY SSF52922 485 619 4.84E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 620 45.727 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 Gene3D G3DSA:3.40.50.970 294 484 8.2E-60 T 29-03-2018 A616_RS13150 66b389c9289e91b5b3000223f4704346 628 ProSitePatterns PS00802 Transketolase signature 2. 418 434 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A616_RS19030 d85f0daf0a7910068afa25dd5466cf51 244 Gene3D G3DSA:3.40.50.1820 3 241 8.7E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS19030 d85f0daf0a7910068afa25dd5466cf51 244 Pfam PF00756 Putative esterase 20 237 7.9E-45 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A616_RS19030 d85f0daf0a7910068afa25dd5466cf51 244 SUPERFAMILY SSF53474 2 240 1.67E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS17560 abc27da061419488f0d0104af071807d 122 SMART SM00850 14 116 5.7E-4 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS17560 abc27da061419488f0d0104af071807d 122 Gene3D G3DSA:2.40.50.40 5 82 3.4E-5 T 29-03-2018 A616_RS17560 abc27da061419488f0d0104af071807d 122 Pfam PF04397 LytTr DNA-binding domain 15 115 9.4E-9 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 SUPERFAMILY SSF81923 5 149 7.46E-34 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Gene3D G3DSA:3.40.50.300 497 718 2.0E-57 T 29-03-2018 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 SMART SM01086 719 808 5.1E-39 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 8.9E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 8.9E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 8.9E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 8.9E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 322 2.3E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 SUPERFAMILY SSF52540 166 472 4.97E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 713 2.1E-57 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 799 2.1E-28 T 29-03-2018 IPR019489 Clp ATPase, C-terminal A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Gene3D G3DSA:1.10.8.60 719 814 5.3E-27 T 29-03-2018 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Gene3D G3DSA:1.10.8.60 350 492 6.9E-45 T 29-03-2018 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Gene3D G3DSA:3.40.50.300 166 348 8.5E-25 T 29-03-2018 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Pfam PF02151 UvrB/uvrC motif 424 456 2.1E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Gene3D G3DSA:1.10.1780.10 1 149 1.7E-46 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 SMART SM00382 542 720 2.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 SMART SM00382 205 350 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 576 594 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 146 1.1E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 1.6E-15 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 A616_RS01230 6ef39a322dac94b09f20369c3a968d93 816 SUPERFAMILY SSF52540 491 807 2.85E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26695 f8a560fc039df01a5c8cced56ea9fb74 168 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS26695 f8a560fc039df01a5c8cced56ea9fb74 168 Pfam PF00293 NUDIX domain 22 138 9.7E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS26695 f8a560fc039df01a5c8cced56ea9fb74 168 Gene3D G3DSA:3.90.79.10 8 158 2.1E-23 T 29-03-2018 A616_RS26695 f8a560fc039df01a5c8cced56ea9fb74 168 SUPERFAMILY SSF55811 15 149 3.25E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 Pfam PF13439 Glycosyltransferase Family 4 18 165 1.2E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 Pfam PF04230 Polysaccharide pyruvyl transferase 390 660 1.0E-22 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 SUPERFAMILY SSF53756 7 367 2.97E-48 T 29-03-2018 A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 Gene3D G3DSA:3.40.50.2000 1 172 1.5E-19 T 29-03-2018 A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 Gene3D G3DSA:3.40.50.2000 173 351 2.2E-22 T 29-03-2018 A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 Gene3D G3DSA:3.40.50.2000 536 684 0.002 T 29-03-2018 A616_RS25070 4448c692d1563bf067c3cec39d322a6c 727 Pfam PF00534 Glycosyl transferases group 1 181 299 5.7E-12 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 Gene3D G3DSA:3.90.1150.10 294 397 1.5E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 Gene3D G3DSA:3.40.640.10 172 293 7.3E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 Gene3D G3DSA:3.90.1150.10 6 167 1.2E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 Pfam PF00202 Aminotransferase class-III 16 395 6.8E-129 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 SUPERFAMILY SSF53383 3 395 1.02E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 64.465 T 29-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 6 395 2.2E-165 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 396 36.916 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 PIRSF PIRSF000521 174 398 1.0E-33 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 PIRSF PIRSF000521 2 159 4.8E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS12645 32f3ba1ffa7a72da2f397c8ebaa90d0d 403 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 SUPERFAMILY SSF48334 253 553 1.28E-91 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 SMART SM00533 270 579 1.3E-108 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Pfam PF05192 MutS domain III 256 547 1.9E-44 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Pfam PF05190 MutS family domain IV 415 506 7.3E-28 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Gene3D G3DSA:1.10.1420.10 249 394 2.2E-38 T 29-03-2018 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 SMART SM00534 597 784 2.6E-112 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Pfam PF00488 MutS domain V 601 787 4.0E-84 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Gene3D G3DSA:3.30.420.110 129 248 1.9E-14 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 SUPERFAMILY SSF53150 114 266 1.57E-27 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Gene3D G3DSA:3.40.1170.10 1 128 9.9E-48 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 SUPERFAMILY SSF55271 2 112 1.44E-42 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Pfam PF05188 MutS domain II 125 174 2.2E-4 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 851 25.03 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Pfam PF01624 MutS domain I 5 115 5.8E-46 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 857 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 678 694 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Gene3D G3DSA:3.40.50.300 555 789 4.3E-43 T 29-03-2018 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 PIRSF PIRSF037677 1 185 3.0E-35 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 PIRSF PIRSF037677 181 831 7.1E-136 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 Gene3D G3DSA:1.10.1420.10 395 523 8.1E-31 T 29-03-2018 A616_RS19520 64d774f69beaa1f2ed06f2d5800a5eef 862 SUPERFAMILY SSF52540 555 787 7.65E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 Pfam PF00890 FAD binding domain 20 391 1.1E-97 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 SUPERFAMILY SSF56425 238 351 9.72E-44 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 PIRSF PIRSF000171 11 540 4.7E-36 T 29-03-2018 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 Gene3D G3DSA:1.20.58.100 422 532 4.0E-26 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 SUPERFAMILY SSF46977 427 529 1.57E-30 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 Gene3D G3DSA:3.90.700.10 244 340 1.4E-36 T 29-03-2018 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 SUPERFAMILY SSF51905 355 408 3.0E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 SUPERFAMILY SSF51905 11 263 3.0E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 Gene3D G3DSA:3.50.50.60 19 239 4.8E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 18 511 1.8E-172 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 Pfam PF02910 Fumarate reductase flavoprotein C-term 435 528 2.3E-19 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 Gene3D G3DSA:3.50.50.60 341 408 7.1E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 376 9.0E-5 T 29-03-2018 A616_RS00860 c3b4128d83e274ce8259d1c7bf57225e 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 9.0E-5 T 29-03-2018 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00086 337 379 0.0028 T 29-03-2018 IPR001610 PAC motif A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00086 91 133 8.6E-4 T 29-03-2018 IPR001610 PAC motif A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00086 217 259 3.3E-7 T 29-03-2018 IPR001610 PAC motif A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00091 19 83 3.6E-4 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00091 145 210 6.3E-11 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00091 271 331 0.024 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 500 604 1.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Gene3D G3DSA:3.30.565.10 441 605 9.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Pfam PF00989 PAS fold 20 130 1.2E-15 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00387 499 606 8.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Gene3D G3DSA:3.30.450.20 139 259 1.2E-32 T 29-03-2018 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Gene3D G3DSA:3.30.450.20 8 138 2.2E-25 T 29-03-2018 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Gene3D G3DSA:1.10.287.130 386 440 2.3E-10 T 29-03-2018 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Gene3D G3DSA:3.30.450.20 260 385 1.7E-27 T 29-03-2018 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SUPERFAMILY SSF55785 130 257 7.68E-27 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Pfam PF08447 PAS fold 311 370 1.5E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Pfam PF08447 PAS fold 168 245 3.0E-17 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 396 455 1.2E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SMART SM00388 394 457 6.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SUPERFAMILY SSF55874 447 604 2.49E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 385 1.8E-12 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 266 2.9E-20 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 140 8.7E-26 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SUPERFAMILY SSF55785 30 140 9.42E-22 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SUPERFAMILY SSF55785 256 377 1.73E-19 T 29-03-2018 IPR000014 PAS domain A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 551 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 565 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 9.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15805 8dd60f79852836189e65384e9742ffe2 606 SUPERFAMILY SSF47384 382 455 5.69E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 Pfam PF04542 Sigma-70 region 2 11 75 3.1E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 161 2.8E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 Pfam PF08281 Sigma-70, region 4 106 157 3.4E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 Gene3D G3DSA:1.10.10.10 73 165 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 SUPERFAMILY SSF88946 7 90 6.28E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 SUPERFAMILY SSF88659 90 165 1.05E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28995 c1958f897b5703c9de80b91fe0eded95 174 Gene3D G3DSA:1.10.1740.10 3 72 7.9E-21 T 29-03-2018 A616_RS27520 9df3ad0ca77a33fdb152f59968858527 260 Gene3D G3DSA:3.90.226.10 1 220 9.7E-77 T 29-03-2018 A616_RS27520 9df3ad0ca77a33fdb152f59968858527 260 Gene3D G3DSA:1.10.12.10 221 258 2.7E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS27520 9df3ad0ca77a33fdb152f59968858527 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS27520 9df3ad0ca77a33fdb152f59968858527 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 259 5.9E-62 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS27520 9df3ad0ca77a33fdb152f59968858527 260 SUPERFAMILY SSF52096 2 259 6.92E-85 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS10290 493e982df77c3cf8726769ef89276393 430 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 239 1.4E-13 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A616_RS10290 493e982df77c3cf8726769ef89276393 430 SUPERFAMILY SSF102735 3 127 2.62E-38 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 SUPERFAMILY SSF109998 250 429 8.37E-44 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS10290 493e982df77c3cf8726769ef89276393 430 Gene3D G3DSA:3.30.70.1050 1 119 1.6E-36 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 PIRSF PIRSF003095 2 430 4.5E-131 T 29-03-2018 IPR005215 Trigger factor GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 Gene3D G3DSA:1.10.3120.10 213 399 3.1E-52 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 423 5.8E-42 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 TIGRFAM TIGR00115 tig: trigger factor 12 423 1.3E-141 T 29-03-2018 IPR005215 Trigger factor GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 SUPERFAMILY SSF54534 89 243 1.59E-36 T 29-03-2018 A616_RS10290 493e982df77c3cf8726769ef89276393 430 Hamap MF_00303 Trigger factor [tig]. 1 429 23.004 T 29-03-2018 IPR005215 Trigger factor GO:0015031 A616_RS10290 493e982df77c3cf8726769ef89276393 430 Pfam PF05697 Bacterial trigger factor protein (TF) 4 145 1.4E-43 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A616_RS30710 d38dd679f2daaaf54c007f5faf85ea3f 453 Gene3D G3DSA:1.10.220.70 56 140 3.0E-30 T 29-03-2018 A616_RS30710 d38dd679f2daaaf54c007f5faf85ea3f 453 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 4.9E-214 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS30710 d38dd679f2daaaf54c007f5faf85ea3f 453 Gene3D G3DSA:3.20.20.70 143 449 1.3E-156 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS30710 d38dd679f2daaaf54c007f5faf85ea3f 453 PIRSF PIRSF018788 1 453 3.5E-225 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS30710 d38dd679f2daaaf54c007f5faf85ea3f 453 Gene3D G3DSA:2.30.170.30 1 53 1.1E-24 T 29-03-2018 A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 Pfam PF01321 Creatinase/Prolidase N-terminal domain 13 144 1.8E-27 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 PRINTS PR00599 Methionine aminopeptidase-1 signature 224 240 1.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 PRINTS PR00599 Methionine aminopeptidase-1 signature 322 334 1.6E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 300 312 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 SUPERFAMILY SSF53092 10 142 4.71E-31 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 Pfam PF00557 Metallopeptidase family M24 152 354 3.8E-69 T 29-03-2018 IPR000994 Peptidase M24 A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 Gene3D G3DSA:3.40.350.10 10 127 2.3E-24 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 Gene3D G3DSA:3.90.230.10 128 372 9.2E-86 T 29-03-2018 A616_RS11335 3e6757b30f06f828fbde0b86290bc0b0 372 SUPERFAMILY SSF55920 143 370 1.44E-82 T 29-03-2018 IPR000994 Peptidase M24 A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 Pfam PF00072 Response regulator receiver domain 9 117 1.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 SMART SM00448 7 117 3.3E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 Gene3D G3DSA:3.40.50.2300 2 123 6.8E-39 T 29-03-2018 A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 Gene3D G3DSA:1.10.10.10 124 226 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 SUPERFAMILY SSF52172 6 180 1.99E-44 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 SMART SM00862 150 224 8.9E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS06680 288dd186a8e5339f80612efc6073ddfe 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 223 8.0E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 SUPERFAMILY SSF63867 363 436 1.31E-10 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Gene3D G3DSA:3.40.980.10 183 358 1.9E-47 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Gene3D G3DSA:3.90.105.10 50 88 4.8E-6 T 29-03-2018 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 SMART SM00852 213 351 1.3E-34 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Gene3D G3DSA:2.40.340.10 361 437 7.1E-10 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Pfam PF03454 MoeA C-terminal region (domain IV) 366 435 1.7E-11 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Pfam PF00994 Probable molybdopterin binding domain 213 349 5.7E-22 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 210 347 3.2E-28 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 SUPERFAMILY SSF63882 33 209 1.1E-49 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Gene3D G3DSA:2.170.190.11 89 174 2.6E-24 T 29-03-2018 A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 SUPERFAMILY SSF53218 210 357 1.01E-36 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS15980 a516de97b5efb269a4099cabe9a177c5 437 Pfam PF03453 MoeA N-terminal region (domain I and II) 33 200 2.8E-39 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Pfam PF08448 PAS fold 288 391 1.3E-9 T 29-03-2018 IPR013656 PAS fold-4 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Pfam PF08448 PAS fold 160 267 7.7E-11 T 29-03-2018 IPR013656 PAS fold-4 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Gene3D G3DSA:3.30.450.20 11 145 2.1E-25 T 29-03-2018 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Pfam PF13426 PAS domain 38 140 7.1E-13 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SUPERFAMILY SSF55785 138 264 7.57E-21 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Gene3D G3DSA:1.10.287.130 399 464 4.9E-13 T 29-03-2018 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SUPERFAMILY SSF55874 458 616 1.7E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00086 224 266 1.0 T 29-03-2018 IPR001610 PAC motif A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00086 348 390 2.4E-4 T 29-03-2018 IPR001610 PAC motif A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00086 99 141 2.0E-6 T 29-03-2018 IPR001610 PAC motif A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00091 27 92 0.81 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00091 278 342 0.98 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00091 153 218 8.5E-4 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00387 509 616 1.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 149 273 8.7E-15 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 276 396 4.9E-11 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 148 9.9E-21 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Gene3D G3DSA:3.30.565.10 468 621 1.5E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SMART SM00388 405 468 5.5E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Pfam PF00512 His Kinase A (phospho-acceptor) domain 407 464 1.5E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Gene3D G3DSA:3.30.450.20 269 398 5.0E-25 T 29-03-2018 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Gene3D G3DSA:3.30.450.20 146 268 1.6E-28 T 29-03-2018 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SUPERFAMILY SSF55785 263 388 6.93E-19 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SUPERFAMILY SSF47384 393 465 3.34E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 SUPERFAMILY SSF55785 38 150 1.69E-22 T 29-03-2018 IPR000014 PAS domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 509 613 9.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 594 4.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 613 4.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 575 4.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29090 36d2872e0c7741d26bf5c5cd991bbcd2 622 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 561 4.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS14620 c0d62dda211470a401187b7d0be554c3 534 Gene3D G3DSA:1.25.40.10 299 522 0.0027 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS14620 c0d62dda211470a401187b7d0be554c3 534 Pfam PF04434 SWIM zinc finger 72 89 1.4E-4 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A616_RS21575 edba28846951e10b99b3b047910d67d5 319 Gene3D G3DSA:3.20.20.70 1 319 2.3E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS21575 edba28846951e10b99b3b047910d67d5 319 SUPERFAMILY SSF51412 1 313 1.98E-65 T 29-03-2018 A616_RS21575 edba28846951e10b99b3b047910d67d5 319 Pfam PF03060 Nitronate monooxygenase 3 73 2.2E-18 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A616_RS21575 edba28846951e10b99b3b047910d67d5 319 Pfam PF03060 Nitronate monooxygenase 76 304 3.1E-46 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A616_RS06180 9752937502eed5f6f115ad767897d527 77 SUPERFAMILY SSF47413 2 63 9.29E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS06180 9752937502eed5f6f115ad767897d527 77 Gene3D G3DSA:3.30.1190.10 26 75 1.2E-5 T 29-03-2018 A616_RS06180 9752937502eed5f6f115ad767897d527 77 Pfam PF01381 Helix-turn-helix 6 59 3.8E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS06180 9752937502eed5f6f115ad767897d527 77 Gene3D G3DSA:1.10.10.60 1 25 1.6E-8 T 29-03-2018 A616_RS06180 9752937502eed5f6f115ad767897d527 77 SMART SM00530 5 60 3.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 4.4E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 SUPERFAMILY SSF46689 5 79 6.16E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 SUPERFAMILY SSF48498 86 187 3.6E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS22505 175cad60dc3e952597224f695356a6a7 198 Gene3D G3DSA:1.10.357.10 80 198 1.4E-12 T 29-03-2018 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 Gene3D G3DSA:1.10.10.60 1 52 7.4E-18 T 29-03-2018 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22505 175cad60dc3e952597224f695356a6a7 198 Gene3D G3DSA:1.10.10.60 53 79 3.1E-9 T 29-03-2018 A616_RS16020 82c22cc606843e7401aa6cb64de9a3b6 433 SUPERFAMILY SSF56601 12 326 4.13E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS16020 82c22cc606843e7401aa6cb64de9a3b6 433 Pfam PF00144 Beta-lactamase 14 322 1.3E-72 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS16020 82c22cc606843e7401aa6cb64de9a3b6 433 Gene3D G3DSA:3.40.710.10 3 332 1.8E-82 T 29-03-2018 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 Gene3D G3DSA:1.10.10.10 111 163 5.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.8E-84 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 Gene3D G3DSA:1.10.601.10 4 110 2.6E-34 T 29-03-2018 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 Pfam PF04545 Sigma-70, region 4 207 255 6.4E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 Gene3D G3DSA:1.10.1270.10 174 259 2.3E-15 T 29-03-2018 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 SUPERFAMILY SSF88946 6 110 1.83E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 3.5E-154 T 29-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 Pfam PF04542 Sigma-70 region 2 42 110 1.9E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 Pfam PF04539 Sigma-70 region 3 124 176 6.3E-7 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 256 5.7E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 SUPERFAMILY SSF88659 175 258 1.14E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 6.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 SUPERFAMILY SSF88659 114 190 5.23E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21240 b2b394a428f1938ca1fff20ed73a6d3a 259 PIRSF PIRSF000770 15 259 2.6E-34 T 29-03-2018 A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 Gene3D G3DSA:2.30.40.10 3 114 5.0E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 Gene3D G3DSA:3.20.20.140 184 487 2.8E-50 T 29-03-2018 A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 SUPERFAMILY SSF51338 489 531 1.35E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 SUPERFAMILY SSF51338 1 61 1.35E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 Pfam PF07969 Amidohydrolase family 50 530 1.8E-98 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 SUPERFAMILY SSF51556 60 123 2.94E-38 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS14250 b2a2749fd3dc0030ffbab128d0009d81 540 SUPERFAMILY SSF51556 198 490 2.94E-38 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS30210 403833ac120ac3e2368678558cc638b2 414 Pfam PF07690 Major Facilitator Superfamily 13 358 9.8E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS30210 403833ac120ac3e2368678558cc638b2 414 Gene3D G3DSA:1.20.1250.20 206 397 7.3E-18 T 29-03-2018 A616_RS30210 403833ac120ac3e2368678558cc638b2 414 SUPERFAMILY SSF103473 12 398 1.7E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS30210 403833ac120ac3e2368678558cc638b2 414 Gene3D G3DSA:1.20.1250.20 1 204 6.8E-19 T 29-03-2018 A616_RS30310 bc2b8dfc1c186fe91156d865ab495d86 314 SUPERFAMILY SSF55120 94 310 3.52E-67 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS30310 bc2b8dfc1c186fe91156d865ab495d86 314 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 310 3.8E-72 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS30310 bc2b8dfc1c186fe91156d865ab495d86 314 Gene3D G3DSA:3.10.290.10 2 74 3.4E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS30310 bc2b8dfc1c186fe91156d865ab495d86 314 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 148 162 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS30310 bc2b8dfc1c186fe91156d865ab495d86 314 Pfam PF00849 RNA pseudouridylate synthase 106 256 1.0E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS30310 bc2b8dfc1c186fe91156d865ab495d86 314 Gene3D G3DSA:3.30.2350.10 97 312 7.8E-66 T 29-03-2018 A616_RS17290 89624ca4e5349fd538bd3db369fef7cb 282 SMART SM00465 1 93 1.1E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS17290 89624ca4e5349fd538bd3db369fef7cb 282 SUPERFAMILY SSF82771 2 89 1.83E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS17290 89624ca4e5349fd538bd3db369fef7cb 282 TIGRFAM TIGR01453 grpIintron_endo: group I intron endonuclease 1 153 1.5E-19 T 29-03-2018 IPR006350 Intron endonuclease, group I GO:0004519 A616_RS17290 89624ca4e5349fd538bd3db369fef7cb 282 Gene3D G3DSA:3.40.1440.10 1 98 2.2E-20 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS17290 89624ca4e5349fd538bd3db369fef7cb 282 Pfam PF01541 GIY-YIG catalytic domain 1 83 7.7E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 Gene3D G3DSA:3.30.450.40 3 174 5.3E-10 T 29-03-2018 IPR029016 GAF domain-like A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 Gene3D G3DSA:1.10.10.10 293 359 1.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 SUPERFAMILY SSF46894 288 352 7.82E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 298 312 9.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 312 328 9.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 328 340 9.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 Pfam PF00196 Bacterial regulatory proteins, luxR family 298 349 5.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 SMART SM00421 295 352 5.6E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS01930 02e37650d27ee0731ed05de9842e4328 362 SUPERFAMILY SSF55781 29 169 1.33E-7 T 29-03-2018 IPR029016 GAF domain-like A616_RS22380 3cd8f1f200201f4242fd6a89f791cd00 331 Pfam PF12679 ABC-2 family transporter protein 8 329 1.5E-22 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 80 94 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 207 226 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 251 270 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 37 53 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 96 109 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 166 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 170 189 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 53 74 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 296 322 5.4E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 PIRSF PIRSF019574 1 351 1.4E-113 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 Gene3D G3DSA:3.40.190.10 149 303 9.9E-46 T 29-03-2018 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 Pfam PF13416 Bacterial extracellular solute-binding protein 47 314 1.2E-43 T 29-03-2018 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 Gene3D G3DSA:3.40.190.10 19 148 3.4E-27 T 29-03-2018 A616_RS24350 bca2ef1635bb4d09e24473fd017783d5 351 SUPERFAMILY SSF53850 31 350 4.23E-94 T 29-03-2018 A616_RS24405 4250629ff7af2edf3d29b46a1fe1d7b3 228 Pfam PF04493 Endonuclease V 22 215 1.5E-74 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A616_RS24405 4250629ff7af2edf3d29b46a1fe1d7b3 228 Hamap MF_00801 Endonuclease V [nfi]. 12 224 33.128 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A616_RS06980 1ff677fc71c3634b955d476d9ccef910 113 Pfam PF02893 GRAM domain 11 85 2.0E-8 T 29-03-2018 IPR004182 GRAM domain A616_RS06980 1ff677fc71c3634b955d476d9ccef910 113 Gene3D G3DSA:2.30.29.30 11 109 1.5E-4 T 29-03-2018 IPR011993 PH domain-like A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 SMART SM00257 97 143 6.8E-11 T 29-03-2018 IPR018392 LysM domain A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 SMART SM00257 48 92 1.2E-13 T 29-03-2018 IPR018392 LysM domain A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Gene3D G3DSA:3.10.350.10 42 88 5.6E-16 T 29-03-2018 A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Gene3D G3DSA:2.70.70.10 141 300 3.2E-45 T 29-03-2018 A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Pfam PF01551 Peptidase family M23 197 294 6.7E-31 T 29-03-2018 IPR016047 Peptidase M23 A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Pfam PF01476 LysM domain 98 143 1.1E-7 T 29-03-2018 IPR018392 LysM domain A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Pfam PF01476 LysM domain 49 91 2.7E-13 T 29-03-2018 IPR018392 LysM domain A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Gene3D G3DSA:1.10.10.60 89 109 0.02 T 29-03-2018 A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 SUPERFAMILY SSF51261 48 298 4.87E-48 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS30075 a1a74269bf53c76d5ad4b155dddb84a7 300 Gene3D G3DSA:3.10.350.10 110 140 1.1E-9 T 29-03-2018 A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 Pfam PF01580 FtsK/SpoIIIE family 437 572 2.3E-49 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 SUPERFAMILY SSF52540 410 696 7.61E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 SMART SM00843 720 785 2.2E-36 T 29-03-2018 IPR018541 FtsK gamma domain A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 SUPERFAMILY SSF46785 723 785 4.62E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 Gene3D G3DSA:3.40.50.300 201 726 2.1E-57 T 29-03-2018 A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 Pfam PF09397 Ftsk gamma domain 723 780 1.5E-28 T 29-03-2018 IPR018541 FtsK gamma domain A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 SMART SM00382 472 645 0.0019 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS19705 95eb3005e20d12c0c89d5647c3abd17f 792 Gene3D G3DSA:1.10.10.10 727 776 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25445 670ad25ad5f6001353b713130b5772d5 314 Gene3D G3DSA:3.30.1330.40 195 313 1.4E-25 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS25445 670ad25ad5f6001353b713130b5772d5 314 Pfam PF01042 Endoribonuclease L-PSP 197 312 1.4E-17 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family A616_RS25445 670ad25ad5f6001353b713130b5772d5 314 SUPERFAMILY SSF55298 189 313 4.24E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS25445 670ad25ad5f6001353b713130b5772d5 314 Pfam PF13302 Acetyltransferase (GNAT) domain 9 152 2.3E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25445 670ad25ad5f6001353b713130b5772d5 314 SUPERFAMILY SSF55729 5 176 1.17E-45 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25445 670ad25ad5f6001353b713130b5772d5 314 Gene3D G3DSA:3.40.630.30 3 194 4.1E-28 T 29-03-2018 A616_RS07280 6dcefb0ca7410ada241f63c76be6ddb2 472 Pfam PF00682 HMGL-like 4 259 4.9E-61 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS07280 6dcefb0ca7410ada241f63c76be6ddb2 472 Gene3D G3DSA:2.60.120.10 336 466 0.0021 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS07280 6dcefb0ca7410ada241f63c76be6ddb2 472 Gene3D G3DSA:3.20.20.70 1 328 1.3E-76 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS07280 6dcefb0ca7410ada241f63c76be6ddb2 472 SUPERFAMILY SSF51569 2 279 1.59E-65 T 29-03-2018 A616_RS07280 6dcefb0ca7410ada241f63c76be6ddb2 472 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 191 204 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS07280 6dcefb0ca7410ada241f63c76be6ddb2 472 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 SMART SM00852 4 170 6.1E-38 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 165 4.5E-30 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 Gene3D G3DSA:3.40.980.10 1 171 2.9E-41 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 266 406 3.1E-42 T 29-03-2018 IPR008136 CinA, C-terminal A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 Pfam PF02464 Competence-damaged protein 259 409 2.4E-53 T 29-03-2018 IPR008136 CinA, C-terminal A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 406 1.8E-141 T 29-03-2018 IPR008135 Competence-induced protein CinA A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 Gene3D G3DSA:3.90.950.20 250 414 7.1E-56 T 29-03-2018 A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 PIRSF PIRSF006728 1 414 4.5E-154 T 29-03-2018 IPR008135 Competence-induced protein CinA A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 SUPERFAMILY SSF142433 252 410 1.57E-48 T 29-03-2018 IPR008136 CinA, C-terminal A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 Pfam PF00994 Probable molybdopterin binding domain 4 169 4.0E-33 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 414 166.198 T 29-03-2018 IPR008135 Competence-induced protein CinA A616_RS19630 45d5aacf1d9942c823476c7c3eb2bb5a 414 SUPERFAMILY SSF53218 1 206 1.11E-40 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 SUPERFAMILY SSF53613 2 297 1.18E-85 T 29-03-2018 IPR029056 Ribokinase-like A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 3 296 3.2E-107 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 PRINTS PR00990 Ribokinase signature 32 51 1.8E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 PRINTS PR00990 Ribokinase signature 214 225 1.8E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 PRINTS PR00990 Ribokinase signature 102 115 1.8E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 PRINTS PR00990 Ribokinase signature 5 26 1.8E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 PRINTS PR00990 Ribokinase signature 170 185 1.8E-34 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 Hamap MF_01987 Ribokinase [rbsK]. 1 298 26.042 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 Pfam PF00294 pfkB family carbohydrate kinase 2 291 8.8E-71 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 Gene3D G3DSA:3.40.1190.20 1 299 1.8E-80 T 29-03-2018 IPR029056 Ribokinase-like A616_RS24400 acf167ada51869ad694d64dfd0a6c2b5 300 PIRSF PIRSF000535 6 296 1.5E-28 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A616_RS17895 cc97b40d7f984df3c2956214fd3c5692 300 SUPERFAMILY SSF103481 188 288 2.75E-15 T 29-03-2018 A616_RS17895 cc97b40d7f984df3c2956214fd3c5692 300 Pfam PF00892 EamA-like transporter family 4 137 4.5E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS17895 cc97b40d7f984df3c2956214fd3c5692 300 Pfam PF00892 EamA-like transporter family 151 285 1.0E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS17895 cc97b40d7f984df3c2956214fd3c5692 300 SUPERFAMILY SSF103481 37 140 7.19E-14 T 29-03-2018 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 Gene3D G3DSA:1.10.8.60 511 608 5.1E-20 T 29-03-2018 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 Pfam PF00989 PAS fold 213 274 1.9E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 Pfam PF00158 Sigma-54 interaction domain 339 504 6.0E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 361 374 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 424 439 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 Gene3D G3DSA:3.40.50.300 332 510 2.6E-27 T 29-03-2018 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 551 560 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 SUPERFAMILY SSF55785 211 269 1.33E-5 T 29-03-2018 IPR000014 PAS domain A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 Gene3D G3DSA:3.30.450.20 213 330 3.0E-6 T 29-03-2018 A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 SMART SM00382 357 502 8.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10170 7715fb42b77c75aa0854057f71ce4b63 691 SUPERFAMILY SSF52540 336 572 2.01E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS17140 a53a387e4efb5ed85876529f94eb2555 138 Gene3D G3DSA:2.30.30.110 3 116 1.3E-34 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A616_RS17140 a53a387e4efb5ed85876529f94eb2555 138 SUPERFAMILY SSF50118 5 114 4.91E-37 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A616_RS17140 a53a387e4efb5ed85876529f94eb2555 138 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 6 111 2.9E-32 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A616_RS17140 a53a387e4efb5ed85876529f94eb2555 138 PIRSF PIRSF033490 2 114 2.2E-34 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A616_RS25215 7c0151f1737a2aff691aae15d7389652 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 291 7.5E-46 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS25215 7c0151f1737a2aff691aae15d7389652 335 Gene3D G3DSA:1.10.3470.10 6 298 1.1E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 PIRSF PIRSF000876 1 368 7.7E-135 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 SUPERFAMILY SSF52738 180 367 1.03E-63 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 368 40.093 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 SUPERFAMILY SSF52172 1 113 2.7E-28 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 Pfam PF00072 Response regulator receiver domain 6 112 1.4E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 Gene3D G3DSA:3.40.50.180 176 368 1.5E-72 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 Gene3D G3DSA:3.40.50.2300 1 175 9.0E-31 T 29-03-2018 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 SMART SM00448 4 127 2.6E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS19930 d328c33eb683da8dd81ee139fdf44bb1 368 Pfam PF01339 CheB methylesterase 183 362 1.5E-58 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A616_RS20845 fa4ac0b6bb3ad02aee26cdd3bdd149b7 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 251 3.9E-47 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS20845 fa4ac0b6bb3ad02aee26cdd3bdd149b7 256 SUPERFAMILY SSF52096 7 255 2.16E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS20845 fa4ac0b6bb3ad02aee26cdd3bdd149b7 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS20845 fa4ac0b6bb3ad02aee26cdd3bdd149b7 256 Gene3D G3DSA:3.90.226.10 1 256 3.4E-71 T 29-03-2018 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 Pfam PF06481 COX Aromatic Rich Motif 241 283 1.3E-4 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 PIRSF PIRSF000292 1 300 1.1E-114 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 SUPERFAMILY SSF81464 22 119 1.41E-22 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 Gene3D G3DSA:1.10.287.90 30 116 3.0E-25 T 29-03-2018 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 Gene3D G3DSA:2.60.40.420 117 281 4.5E-44 T 29-03-2018 IPR008972 Cupredoxin A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 16 241 5.7E-86 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 SUPERFAMILY SSF49503 122 263 3.96E-42 T 29-03-2018 IPR008972 Cupredoxin A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 50 110 9.4E-6 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28540 022481b0c46cc7a9939743537d2742d9 301 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 15 241 1.2E-73 T 29-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 A616_RS10270 e477e834e8c4bc883cebdc90d64b0e17 350 Pfam PF10646 Sporulation and spore germination 218 330 3.5E-20 T 29-03-2018 IPR019606 GerMN domain A616_RS10270 e477e834e8c4bc883cebdc90d64b0e17 350 Pfam PF10646 Sporulation and spore germination 73 182 8.9E-21 T 29-03-2018 IPR019606 GerMN domain A616_RS10270 e477e834e8c4bc883cebdc90d64b0e17 350 SMART SM00909 246 334 7.6E-22 T 29-03-2018 IPR019606 GerMN domain A616_RS10270 e477e834e8c4bc883cebdc90d64b0e17 350 SMART SM00909 96 186 3.3E-18 T 29-03-2018 IPR019606 GerMN domain A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 Pfam PF00072 Response regulator receiver domain 4 113 4.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 SMART SM00448 2 112 4.4E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 SUPERFAMILY SSF46894 130 229 1.98E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 Gene3D G3DSA:1.10.10.10 129 230 4.9E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 1.7E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 Gene3D G3DSA:3.40.50.2300 1 128 1.4E-32 T 29-03-2018 A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 SUPERFAMILY SSF52172 1 123 3.7E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS25880 60def0d838304f5ec1a3ccb45a49e7e9 231 SMART SM00862 153 229 8.4E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 SUPERFAMILY SSF51445 195 473 3.73E-24 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 Gene3D G3DSA:3.30.457.10 19 64 4.0E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 Gene3D G3DSA:3.30.457.10 65 135 1.7E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 Pfam PF02638 Glycosyl hydrolase-like 10 179 489 6.5E-95 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 Pfam PF07833 Copper amine oxidase N-terminal domain 54 143 3.3E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 Gene3D G3DSA:3.20.20.80 183 520 2.9E-47 T 29-03-2018 A616_RS31310 99c80b4fb0b9061de42ed3739ca17e49 540 SUPERFAMILY SSF55383 57 139 1.37E-24 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS03565 011dbd66939910cab9f29059bc379566 472 Gene3D G3DSA:3.40.50.2020 239 439 4.1E-36 T 29-03-2018 A616_RS03565 011dbd66939910cab9f29059bc379566 472 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 14 458 2.0E-167 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A616_RS03565 011dbd66939910cab9f29059bc379566 472 PIRSF PIRSF000485 10 471 1.4E-184 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A616_RS03565 011dbd66939910cab9f29059bc379566 472 SUPERFAMILY SSF53271 248 463 5.51E-75 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS03565 011dbd66939910cab9f29059bc379566 472 Pfam PF13522 Glutamine amidotransferase domain 73 206 3.4E-21 T 29-03-2018 A616_RS03565 011dbd66939910cab9f29059bc379566 472 SUPERFAMILY SSF56235 14 238 5.06E-71 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS03565 011dbd66939910cab9f29059bc379566 472 Pfam PF00156 Phosphoribosyl transferase domain 276 383 4.7E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS03565 011dbd66939910cab9f29059bc379566 472 Gene3D G3DSA:3.60.20.10 152 238 3.8E-21 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS03565 011dbd66939910cab9f29059bc379566 472 Gene3D G3DSA:3.60.20.10 12 151 6.1E-39 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS03565 011dbd66939910cab9f29059bc379566 472 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 13 457 47.401 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A616_RS24235 0e094b084c713bdb3db5b58bc995bc4e 157 SUPERFAMILY SSF75217 1 155 7.19E-37 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS24235 0e094b084c713bdb3db5b58bc995bc4e 157 Pfam PF02590 Predicted SPOUT methyltransferase 1 155 4.4E-39 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24235 0e094b084c713bdb3db5b58bc995bc4e 157 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 157 20.947 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24235 0e094b084c713bdb3db5b58bc995bc4e 157 PIRSF PIRSF004505 1 156 3.5E-35 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24235 0e094b084c713bdb3db5b58bc995bc4e 157 Gene3D G3DSA:3.40.1280.10 1 156 3.2E-39 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS23810 d7c07845340dc157ba3cf969c46ec3c2 231 SUPERFAMILY SSF161098 27 213 1.18E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS23810 d7c07845340dc157ba3cf969c46ec3c2 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 228 1.3E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS23810 d7c07845340dc157ba3cf969c46ec3c2 231 Gene3D G3DSA:1.10.3720.10 2 231 4.6E-43 T 29-03-2018 A616_RS23810 d7c07845340dc157ba3cf969c46ec3c2 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 25 122 1.0E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Pfam PF02151 UvrB/uvrC motif 624 656 3.2E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Gene3D G3DSA:3.40.50.300 9 414 1.3E-31 T 29-03-2018 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 SUPERFAMILY SSF52540 2 413 2.27E-140 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Pfam PF12344 Ultra-violet resistance protein B 550 592 3.4E-24 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Gene3D G3DSA:4.10.860.10 594 658 1.1E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 SUPERFAMILY SSF46600 612 656 2.09E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 SUPERFAMILY SSF52540 31 66 8.1E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 SUPERFAMILY SSF52540 455 585 8.1E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 SMART SM00490 458 544 6.5E-22 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 SMART SM00487 8 424 3.3E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Pfam PF04851 Type III restriction enzyme, res subunit 10 138 3.6E-12 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Pfam PF00271 Helicase conserved C-terminal domain 440 543 1.4E-18 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Gene3D G3DSA:3.40.50.300 415 587 2.4E-32 T 29-03-2018 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 657 44.694 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A616_RS29265 ba043c806aa61620405e7ba2fd0c0a49 658 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 655 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Pfam PF00395 S-layer homology domain 305 329 3.9E-9 T 29-03-2018 IPR001119 S-layer homology domain A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Pfam PF00395 S-layer homology domain 350 390 1.0E-12 T 29-03-2018 IPR001119 S-layer homology domain A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Pfam PF00395 S-layer homology domain 410 448 7.8E-12 T 29-03-2018 IPR001119 S-layer homology domain A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Gene3D G3DSA:1.20.1270.90 118 185 4.3E-12 T 29-03-2018 A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Pfam PF07554 FIVAR domain 119 183 0.0021 T 29-03-2018 A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Pfam PF07554 FIVAR domain 206 251 1.1E-4 T 29-03-2018 A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Pfam PF07554 FIVAR domain 51 103 7.6E-6 T 29-03-2018 A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Gene3D G3DSA:1.20.1270.90 189 282 2.9E-15 T 29-03-2018 A616_RS08380 3bd5a14d7675a41e243346f14216e9be 489 Gene3D G3DSA:1.20.1270.90 45 117 3.3E-13 T 29-03-2018 A616_RS01750 dd1bc34da77c03181bca3828ce249aa1 97 Gene3D G3DSA:1.20.1260.10 1 73 1.2E-10 T 29-03-2018 IPR012347 Ferritin-related A616_RS01750 dd1bc34da77c03181bca3828ce249aa1 97 Pfam PF07875 Coat F domain 15 76 1.6E-23 T 29-03-2018 IPR012851 Spore coat protein CotF-like A616_RS23940 35da143caf4272c13cbf136f93237e49 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 3.3E-32 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 PRINTS PR00421 Thioredoxin family signature 29 38 2.6E-6 T 29-03-2018 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 PRINTS PR00421 Thioredoxin family signature 69 80 2.6E-6 T 29-03-2018 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 PRINTS PR00421 Thioredoxin family signature 21 29 2.6E-6 T 29-03-2018 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 Pfam PF00085 Thioredoxin 4 103 2.6E-27 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 PIRSF PIRSF000077 1 105 2.2E-33 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 SUPERFAMILY SSF52833 6 104 2.14E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS23940 35da143caf4272c13cbf136f93237e49 105 Gene3D G3DSA:3.40.30.10 3 67 2.7E-25 T 29-03-2018 A616_RS23940 35da143caf4272c13cbf136f93237e49 105 Gene3D G3DSA:3.40.30.10 68 104 2.3E-5 T 29-03-2018 A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 Pfam PF00005 ABC transporter 39 189 2.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 306 1.1E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 SMART SM00382 47 255 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 326 7.5E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 SUPERFAMILY SSF52540 11 261 1.16E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25610 ae2b5f0f71e04d5de75a5c9498db648d 327 Gene3D G3DSA:3.40.50.300 8 327 6.2E-83 T 29-03-2018 A616_RS00730 37921132c503999e97ef6ab12822c8a1 97 Gene3D G3DSA:3.10.290.10 1 96 2.8E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00730 37921132c503999e97ef6ab12822c8a1 97 Pfam PF01479 S4 domain 1 46 1.2E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00730 37921132c503999e97ef6ab12822c8a1 97 PIRSF PIRSF038881 1 89 7.0E-32 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type A616_RS00730 37921132c503999e97ef6ab12822c8a1 97 SMART SM00363 1 64 1.6E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00730 37921132c503999e97ef6ab12822c8a1 97 SUPERFAMILY SSF55174 1 76 1.44E-18 T 29-03-2018 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 442 458 2.4E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 322 342 2.4E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 358 374 2.4E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 379 390 2.4E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 77 128 1.8E-15 T 29-03-2018 IPR011096 FTP domain A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Gene3D G3DSA:1.10.390.10 372 528 1.1E-51 T 29-03-2018 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 225 367 1.3E-49 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Pfam PF03413 Peptidase propeptide and YPEB domain 146 218 6.4E-11 T 29-03-2018 IPR025711 PepSY domain A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Gene3D G3DSA:3.10.170.10 224 371 1.7E-54 T 29-03-2018 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Gene3D G3DSA:3.10.450.40 144 220 0.0022 T 29-03-2018 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 SUPERFAMILY SSF55486 223 527 2.2E-103 T 29-03-2018 A616_RS07635 d2fcb65ec9903e57564af26128673f14 528 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 370 527 1.0E-59 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 A616_RS00445 ecfafb124950ad3028214e85610087c1 74 SUPERFAMILY SSF64307 3 73 7.46E-25 T 29-03-2018 IPR001455 TusA-like domain A616_RS00445 ecfafb124950ad3028214e85610087c1 74 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 29-03-2018 IPR001455 TusA-like domain A616_RS00445 ecfafb124950ad3028214e85610087c1 74 Pfam PF01206 Sulfurtransferase TusA 4 73 3.6E-25 T 29-03-2018 IPR001455 TusA-like domain A616_RS00445 ecfafb124950ad3028214e85610087c1 74 Gene3D G3DSA:3.30.110.40 1 74 3.5E-29 T 29-03-2018 IPR001455 TusA-like domain A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 18 180 8.5E-52 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 ProSitePatterns PS00501 Signal peptidases I serine active site. 44 51 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 35 51 2.2E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 85 97 2.2E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 140 159 2.2E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 Gene3D G3DSA:2.10.109.10 31 185 1.6E-46 T 29-03-2018 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 ProSitePatterns PS00761 Signal peptidases I signature 3. 145 158 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 SUPERFAMILY SSF51306 33 185 3.24E-49 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS20215 e3a79dc9874f14ccd4893e117a92a6fa 187 Pfam PF00717 Peptidase S24-like 42 105 3.7E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 Gene3D G3DSA:1.10.10.10 127 208 1.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 SUPERFAMILY SSF52172 2 131 3.84E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 Pfam PF00072 Response regulator receiver domain 4 116 9.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 2.2E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 SMART SM00448 2 115 1.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 SMART SM00421 146 203 3.2E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 Gene3D G3DSA:3.40.50.2300 1 126 5.6E-34 T 29-03-2018 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.4E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.4E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.4E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS05715 b6acf137acfe8958cedc3e7ff80474aa 209 SUPERFAMILY SSF46894 138 206 8.16E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 804 23.201 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Gene3D G3DSA:3.40.50.620 2 314 9.2E-102 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.5E-18 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 SUPERFAMILY SSF47323 619 804 7.85E-36 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 SUPERFAMILY SSF52374 4 224 1.02E-146 T 29-03-2018 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 SUPERFAMILY SSF52374 411 625 1.02E-146 T 29-03-2018 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 1.5E-69 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 SUPERFAMILY SSF50677 224 408 5.65E-54 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 804 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 3.1E-20 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.5E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Gene3D G3DSA:3.40.50.620 351 604 3.8E-76 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Pfam PF08264 Anticodon-binding domain of tRNA 657 766 3.2E-19 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A616_RS11245 5e8625a13e16e3faf4a374bf4d1cd8fd 805 Gene3D G3DSA:1.10.730.10 605 741 3.5E-29 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS03575 592f51633099e6702c499f91f4c2c8fd 202 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS03575 592f51633099e6702c499f91f4c2c8fd 202 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 190 31.533 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A616_RS03575 592f51633099e6702c499f91f4c2c8fd 202 SUPERFAMILY SSF53328 4 196 4.71E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS03575 592f51633099e6702c499f91f4c2c8fd 202 Pfam PF00551 Formyl transferase 4 184 4.8E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS03575 592f51633099e6702c499f91f4c2c8fd 202 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 4 194 3.4E-68 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A616_RS03575 592f51633099e6702c499f91f4c2c8fd 202 Gene3D G3DSA:3.40.50.170 2 200 1.9E-65 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 Gene3D G3DSA:3.40.50.2300 1 121 7.1E-38 T 29-03-2018 A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 SUPERFAMILY SSF52172 3 175 2.64E-42 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 220 4.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 Pfam PF00072 Response regulator receiver domain 5 112 9.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 SMART SM00448 3 113 9.2E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 Gene3D G3DSA:1.10.10.10 122 224 2.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16155 6af4eb8afbec96b7ff01cb7ae01219d3 224 SMART SM00862 147 220 4.4E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 Gene3D G3DSA:1.25.40.10 165 233 1.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 Gene3D G3DSA:1.20.58.280 94 115 1.0E-5 T 29-03-2018 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 Gene3D G3DSA:1.25.40.10 116 164 1.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 Pfam PF13432 Tetratricopeptide repeat 53 114 4.2E-6 T 29-03-2018 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 SMART SM00028 82 115 0.066 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 SMART SM00028 183 216 25.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 SMART SM00028 150 182 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 SMART SM00028 48 81 9.8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 SMART SM00028 116 149 30.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 Pfam PF13181 Tetratricopeptide repeat 193 215 0.032 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 Gene3D G3DSA:1.25.40.10 52 93 4.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29735 cb9367830cbf2da03d79ac7f1f77396a 233 SUPERFAMILY SSF48452 52 216 2.49E-30 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS24580 a28377eedb86958f58cf673453dc0e17 176 Gene3D G3DSA:2.60.200.20 31 161 1.1E-16 T 29-03-2018 A616_RS24580 a28377eedb86958f58cf673453dc0e17 176 SUPERFAMILY SSF49879 57 162 4.02E-15 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 A616_RS24580 a28377eedb86958f58cf673453dc0e17 176 Pfam PF00498 FHA domain 86 152 8.7E-7 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.701 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 SUPERFAMILY SSF46589 15 100 2.41E-21 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 6.0E-108 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 SUPERFAMILY SSF55681 93 342 2.75E-82 T 29-03-2018 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 22 88 1.4E-26 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 Gene3D G3DSA:3.30.930.10 8 344 1.5E-93 T 29-03-2018 A616_RS09580 d6e2fc58c8228f4b6a3264c230f827b2 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 342 1.8E-110 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 SUPERFAMILY SSF50447 3 74 2.26E-15 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 Pfam PF01411 tRNA synthetases class II (A) 16 90 3.8E-8 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 Gene3D G3DSA:3.30.980.10 88 242 4.7E-33 T 29-03-2018 A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 183 223 1.0E-9 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 Pfam PF02272 DHHA1 domain 262 396 2.0E-8 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 SUPERFAMILY SSF55186 91 232 7.72E-35 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A616_RS18015 94df7a4c7b44d020aa258758d4149379 403 SMART SM00863 183 225 9.2E-12 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Pfam PF13522 Glutamine amidotransferase domain 64 188 6.4E-23 T 29-03-2018 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Gene3D G3DSA:3.40.50.10490 459 608 3.0E-44 T 29-03-2018 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.309 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 7.8E-249 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 SUPERFAMILY SSF53697 245 610 7.22E-107 T 29-03-2018 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Pfam PF01380 SIS domain 295 416 5.3E-33 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Pfam PF01380 SIS domain 463 591 1.2E-21 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Gene3D G3DSA:3.40.50.10490 240 458 5.8E-71 T 29-03-2018 A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 Gene3D G3DSA:3.60.20.10 2 239 1.6E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS07830 ee96c38073a8ba897ae2e2175f69c24b 610 SUPERFAMILY SSF56235 2 225 3.6E-72 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS20885 07e6e70743595ed87b958b81dbbe7c04 183 SUPERFAMILY SSF56399 10 179 6.62E-23 T 29-03-2018 A616_RS20885 07e6e70743595ed87b958b81dbbe7c04 183 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 7 170 3.0E-14 T 29-03-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 433 448 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 Gene3D G3DSA:3.40.50.300 339 518 1.2E-24 T 29-03-2018 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 555 564 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 Pfam PF00989 PAS fold 220 271 1.1E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 Pfam PF00158 Sigma-54 interaction domain 346 513 1.5E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 SMART SM00382 366 511 2.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 SMART SM00091 219 285 9.6E-10 T 29-03-2018 IPR000014 PAS domain A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 219 327 4.3E-7 T 29-03-2018 IPR000014 PAS domain A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 Gene3D G3DSA:3.30.450.20 201 336 3.8E-15 T 29-03-2018 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 Gene3D G3DSA:1.10.8.60 519 591 3.3E-21 T 29-03-2018 A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 SUPERFAMILY SSF55785 215 319 8.19E-12 T 29-03-2018 IPR000014 PAS domain A616_RS04810 3667901cf44f4c01e25eb9d50e445bef 698 SUPERFAMILY SSF52540 346 585 2.97E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 4.6E-68 T 29-03-2018 IPR023798 Ribosomal protein S7 domain A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 SUPERFAMILY SSF47973 1 149 1.44E-63 T 29-03-2018 IPR023798 Ribosomal protein S7 domain A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.221 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.6E-70 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 PIRSF PIRSF002122 5 156 6.2E-60 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A616_RS01365 0c9db65b78c6f3e285bbc787cf8e49aa 156 Gene3D G3DSA:1.10.455.10 7 156 1.5E-61 T 29-03-2018 IPR023798 Ribosomal protein S7 domain A616_RS18955 b969494079ba8dedca9135f60b8953e3 197 Pfam PF07285 Protein of unknown function (DUF1444) 4 188 1.0E-57 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 Gene3D G3DSA:2.40.37.10 555 717 8.1E-60 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 TIGRFAM TIGR00492 alr: alanine racemase 349 715 6.6E-110 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 Pfam PF00842 Alanine racemase, C-terminal domain 587 715 6.8E-44 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 Pfam PF01168 Alanine racemase, N-terminal domain 354 570 8.5E-61 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 603 618 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 409 427 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 466 478 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 499 510 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 373 389 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 545 572 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 620 635 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 PRINTS PR00992 Alanine racemase signature 698 711 7.7E-43 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 SUPERFAMILY SSF51419 354 588 1.44E-57 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 Hamap MF_01201 Alanine racemase. 347 716 32.215 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 Gene3D G3DSA:3.20.20.10 356 554 4.9E-40 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 SMART SM01005 587 716 5.6E-63 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 SUPERFAMILY SSF50621 580 716 8.02E-46 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS03520 e1036edbd77269db2a957185d42e73ac 717 Pfam PF01757 Acyltransferase family 11 331 9.4E-24 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 SUPERFAMILY SSF55347 152 314 1.31E-73 T 29-03-2018 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.2E-137 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.5E-68 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 SUPERFAMILY SSF51735 1 178 3.95E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS08090 8943daa004405707e686ff9ec7372be9 348 Gene3D G3DSA:3.30.360.10 162 315 3.7E-69 T 29-03-2018 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 Gene3D G3DSA:3.40.50.720 1 161 3.6E-77 T 29-03-2018 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 PIRSF PIRSF000149 1 335 1.2E-139 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 SMART SM00846 3 152 9.6E-91 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS08090 8943daa004405707e686ff9ec7372be9 348 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 4.5E-37 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 SUPERFAMILY SSF49265 950 1044 5.52E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 Pfam PF00912 Transglycosylase 83 266 4.8E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 SUPERFAMILY SSF49265 812 899 4.81E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 Pfam PF00905 Penicillin binding protein transpeptidase domain 401 646 4.3E-29 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 SUPERFAMILY SSF53955 76 291 2.81E-64 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 SUPERFAMILY SSF56601 251 270 1.94E-103 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 SUPERFAMILY SSF56601 329 748 1.94E-103 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 Gene3D G3DSA:3.40.710.10 289 731 2.6E-97 T 29-03-2018 A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 Gene3D G3DSA:2.60.40.10 957 1046 3.2E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 Gene3D G3DSA:2.60.40.10 813 919 2.0E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS22955 693f97a25ba823b5128f16622d69a9f3 1046 Gene3D G3DSA:1.10.3810.10 76 283 2.0E-67 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS23590 c3f0df453dddf3722df81b9b96a3ebcb 214 Pfam PF02390 Putative methyltransferase 37 206 1.9E-49 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A616_RS23590 c3f0df453dddf3722df81b9b96a3ebcb 214 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 25 209 1.3E-56 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A616_RS23590 c3f0df453dddf3722df81b9b96a3ebcb 214 SUPERFAMILY SSF53335 24 208 1.28E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS23590 c3f0df453dddf3722df81b9b96a3ebcb 214 Gene3D G3DSA:3.40.50.150 8 211 3.9E-31 T 29-03-2018 A616_RS23590 c3f0df453dddf3722df81b9b96a3ebcb 214 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 28.838 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 Gene3D G3DSA:3.40.50.2020 75 274 6.9E-34 T 29-03-2018 A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 74 2.0E-13 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 271 3.8E-115 T 29-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 SUPERFAMILY SSF46785 3 74 1.52E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 SUPERFAMILY SSF53271 92 258 1.7E-40 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 Gene3D G3DSA:1.10.10.10 1 74 1.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 Pfam PF09182 Bacterial purine repressor, N-terminal 5 74 2.2E-29 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 A616_RS00660 79c172e28418fc1da6dba57529c02efa 277 Pfam PF00156 Phosphoribosyl transferase domain 108 246 3.3E-23 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 Gene3D G3DSA:1.20.1250.20 208 403 2.1E-21 T 29-03-2018 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 Pfam PF07690 Major Facilitator Superfamily 25 336 3.0E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 PRINTS PR01035 Tetracycline resistance protein signature 150 172 1.4E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 PRINTS PR01035 Tetracycline resistance protein signature 379 398 1.4E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 PRINTS PR01035 Tetracycline resistance protein signature 57 76 1.4E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 PRINTS PR01035 Tetracycline resistance protein signature 27 43 1.4E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 Gene3D G3DSA:1.20.1250.20 16 207 1.6E-29 T 29-03-2018 A616_RS14570 4af21fbf1625cc80b3d1630de568eb00 403 SUPERFAMILY SSF103473 14 400 1.57E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 PIRSF PIRSF000077 1 105 3.4E-42 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 104 5.2E-39 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 SUPERFAMILY SSF52833 3 105 1.64E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 Pfam PF00085 Thioredoxin 3 103 1.7E-31 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 PRINTS PR00421 Thioredoxin family signature 29 38 6.8E-10 T 29-03-2018 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 PRINTS PR00421 Thioredoxin family signature 21 29 6.8E-10 T 29-03-2018 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 PRINTS PR00421 Thioredoxin family signature 69 80 6.8E-10 T 29-03-2018 A616_RS09730 b232f5ed05b900b99ef6355c753eda07 105 Gene3D G3DSA:3.40.30.10 1 105 4.7E-36 T 29-03-2018 A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 Gene3D G3DSA:3.40.50.300 4 337 1.6E-80 T 29-03-2018 A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 1.4E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 SUPERFAMILY SSF52540 7 257 4.8E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 SMART SM00382 36 244 4.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 5.2E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS10190 5e82555eaa1973737b46909d4c6c0ed2 342 Pfam PF00005 ABC transporter 28 186 3.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 225 2.5E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 SUPERFAMILY SSF46894 122 226 1.3E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 SUPERFAMILY SSF49879 11 105 5.74E-21 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 SMART SM00862 145 225 1.2E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 Gene3D G3DSA:1.10.10.10 126 227 5.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 SMART SM00240 28 81 2.2E-6 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 Pfam PF00498 FHA domain 29 96 1.7E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A616_RS07120 6cee3a9205d959916b9b7f68a682595c 227 Gene3D G3DSA:2.60.200.20 3 125 2.1E-19 T 29-03-2018 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 SUPERFAMILY SSF54719 221 336 1.09E-43 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 298 305 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 Gene3D G3DSA:1.10.287.990 159 222 4.3E-20 T 29-03-2018 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 142 222 1.4E-26 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 PRINTS PR01703 Manganese superoxide dismutase signature 296 308 9.3E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 PRINTS PR01703 Manganese superoxide dismutase signature 145 156 9.3E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 PRINTS PR01703 Manganese superoxide dismutase signature 166 179 9.3E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 PRINTS PR01703 Manganese superoxide dismutase signature 258 266 9.3E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 PRINTS PR01703 Manganese superoxide dismutase signature 205 218 9.3E-19 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 229 331 2.1E-36 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS10260 a0232b31f87f3c699805a8f98b204bcd 343 SUPERFAMILY SSF46609 140 227 4.32E-32 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Gene3D G3DSA:2.40.240.10 345 465 3.6E-53 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 30 338 3.8E-108 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 341 529 1.3E-62 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 31 550 1.4E-225 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 2 550 51.506 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 36 47 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Gene3D G3DSA:2.40.240.10 466 548 1.3E-31 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Gene3D G3DSA:3.40.50.620 30 154 3.4E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Gene3D G3DSA:3.40.50.620 156 261 4.2E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 SUPERFAMILY SSF52374 30 347 4.22E-98 T 29-03-2018 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 221 1.9E-11 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 47 58 1.9E-11 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 62 75 1.9E-11 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 45 1.9E-11 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 Gene3D G3DSA:1.10.1160.10 262 338 4.0E-34 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A616_RS30450 a9a326861a62bc1e57e0b0c100f8c991 555 SUPERFAMILY SSF50715 341 548 7.85E-77 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 314 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 SUPERFAMILY SSF103473 14 431 5.1E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 Gene3D G3DSA:1.20.1250.20 8 224 1.7E-25 T 29-03-2018 A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 Pfam PF00083 Sugar (and other) transporter 17 223 8.0E-21 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 Pfam PF07690 Major Facilitator Superfamily 255 418 1.1E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS27200 cbdb9ce65fb3a92bfa3cc01283a8e81d 433 Gene3D G3DSA:1.20.1250.20 225 433 6.2E-24 T 29-03-2018 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 557 1.5E-255 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 SUPERFAMILY SSF143975 4 376 6.93E-138 T 29-03-2018 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 Gene3D G3DSA:3.40.50.2300 37 254 0.0012 T 29-03-2018 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 557 47.458 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 SUPERFAMILY SSF52016 377 556 2.43E-63 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A616_RS23565 17b733e0b72501ee1f9c531df5c4b2ec 558 Pfam PF00920 Dehydratase family 34 553 1.5E-228 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 Gene3D G3DSA:3.40.50.300 9 331 5.6E-85 T 29-03-2018 A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 4.9E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 SUPERFAMILY SSF52540 12 263 9.43E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 328 1.1E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 Pfam PF00005 ABC transporter 40 191 1.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14645 52e6ddc948cd7cb01af80a28ba7e6e38 331 SMART SM00382 48 241 5.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS22190 9dce6f854282f3b5fbf4f11de170edc5 171 Gene3D G3DSA:1.10.10.60 4 43 2.8E-14 T 29-03-2018 A616_RS22190 9dce6f854282f3b5fbf4f11de170edc5 171 SUPERFAMILY SSF46689 3 69 7.98E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS22190 9dce6f854282f3b5fbf4f11de170edc5 171 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22190 9dce6f854282f3b5fbf4f11de170edc5 171 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22190 9dce6f854282f3b5fbf4f11de170edc5 171 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 4.8E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22190 9dce6f854282f3b5fbf4f11de170edc5 171 Gene3D G3DSA:1.10.10.60 44 108 5.3E-9 T 29-03-2018 A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 SUPERFAMILY SSF54768 8 75 4.92E-24 T 29-03-2018 A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 156 2.8E-30 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 74 2.2E-31 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 Gene3D G3DSA:3.30.230.10 75 165 5.0E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 Gene3D G3DSA:3.30.160.20 9 71 9.4E-30 T 29-03-2018 A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 SUPERFAMILY SSF54211 79 158 1.77E-25 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 8 162 1.4E-70 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A616_RS01485 2eadeeade3a31c7a3038c5377333beef 165 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 35.852 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Pfam PF13414 TPR repeat 451 492 8.5E-10 T 29-03-2018 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.25.40.10 646 711 3.2E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.25.40.10 490 521 4.9E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Pfam PF13181 Tetratricopeptide repeat 513 545 0.0074 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Pfam PF00515 Tetratricopeptide repeat 616 645 1.5E-7 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.10.8.10 477 489 0.0035 T 29-03-2018 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.25.40.10 522 579 6.8E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.20.58.280 427 476 1.5E-9 T 29-03-2018 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SUPERFAMILY SSF48452 366 481 6.45E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.10.150.200 314 422 0.0017 T 29-03-2018 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 648 680 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 546 579 0.59 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 614 647 1.7E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 444 477 3.0E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 682 715 82.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 512 545 4.1E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 478 511 4.0E-8 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SMART SM00028 580 613 0.077 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.10.287.1110 633 645 4.3E-4 T 29-03-2018 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 SUPERFAMILY SSF48452 447 697 2.91E-40 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS04270 eb8757efd23a871943a824e5138d0ce0 731 Gene3D G3DSA:1.25.40.10 580 632 2.2E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 2.1E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 SUPERFAMILY SSF52172 1 122 2.7E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 Pfam PF00072 Response regulator receiver domain 3 113 4.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 SUPERFAMILY SSF46894 123 220 2.52E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 Gene3D G3DSA:3.40.50.2300 1 120 2.6E-36 T 29-03-2018 A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 SMART SM00448 1 112 9.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 Gene3D G3DSA:1.10.10.10 121 224 1.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02095 a014f24f3b6b71eaad8114128a1c4513 224 SMART SM00862 146 219 8.7E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS03340 855b6a7df2514c45a7609f2046876d37 123 SMART SM00448 2 114 8.0E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03340 855b6a7df2514c45a7609f2046876d37 123 Pfam PF00072 Response regulator receiver domain 4 114 9.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03340 855b6a7df2514c45a7609f2046876d37 123 SUPERFAMILY SSF52172 2 119 1.85E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03340 855b6a7df2514c45a7609f2046876d37 123 Gene3D G3DSA:3.40.50.2300 2 123 2.6E-35 T 29-03-2018 A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 Gene3D G3DSA:3.40.50.720 15 122 6.2E-26 T 29-03-2018 A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 46 142 1.0E-18 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 Gene3D G3DSA:3.40.50.720 123 292 1.2E-52 T 29-03-2018 A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 SUPERFAMILY SSF51735 111 291 1.91E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 SUPERFAMILY SSF52283 16 137 6.43E-23 T 29-03-2018 A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 290 5.3E-56 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A616_RS27790 96c8a42d92e6883155a6c62d277c0963 327 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 155 182 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A616_RS23475 4e540f1e1ec005351704988648285708 201 SUPERFAMILY SSF52540 26 197 7.53E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23475 4e540f1e1ec005351704988648285708 201 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 11 195 1.4E-85 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS23475 4e540f1e1ec005351704988648285708 201 Pfam PF01583 Adenylylsulphate kinase 28 183 4.6E-73 T 29-03-2018 A616_RS23475 4e540f1e1ec005351704988648285708 201 Gene3D G3DSA:3.40.50.300 24 201 9.2E-56 T 29-03-2018 A616_RS23475 4e540f1e1ec005351704988648285708 201 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 27 199 38.821 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 SUPERFAMILY SSF46689 3 70 1.55E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 SUPERFAMILY SSF48498 78 186 2.26E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 Gene3D G3DSA:1.10.357.10 2 189 1.8E-33 T 29-03-2018 A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 56 188 1.4E-38 T 29-03-2018 IPR032551 HTH-type transcriptional repressor, C-terminal A616_RS09030 6ccdcdb9bc5720d18339b9f6da9ecb25 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 2.3E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 SUPERFAMILY SSF53187 9 196 4.29E-63 T 29-03-2018 A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 SUPERFAMILY SSF53187 334 419 4.29E-63 T 29-03-2018 A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 Pfam PF01546 Peptidase family M20/M25/M40 97 415 2.9E-38 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 Gene3D G3DSA:3.40.630.10 2 312 7.6E-61 T 29-03-2018 A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 SUPERFAMILY SSF55031 203 311 2.09E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 Pfam PF07687 Peptidase dimerisation domain 202 312 1.2E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS11825 be115b5531dd159626ff5eb122d2e719 426 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 404 6.0E-107 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A616_RS05760 06cc7f715856d50b36cee176580655ba 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 2.1E-26 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.1E-26 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.1E-26 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 2.1E-26 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 2.1E-26 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 2.3E-42 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 SUPERFAMILY SSF54719 92 201 3.4E-48 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 SUPERFAMILY SSF46609 1 91 6.68E-38 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 Gene3D G3DSA:1.10.287.990 20 90 1.9E-32 T 29-03-2018 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 PIRSF PIRSF000349 1 202 1.8E-86 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS05760 06cc7f715856d50b36cee176580655ba 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 8.0E-32 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 Gene3D G3DSA:1.10.357.10 53 189 1.5E-15 T 29-03-2018 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 Pfam PF08359 YsiA-like protein, C-terminal region 54 154 2.6E-5 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 52 5.8E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 Gene3D G3DSA:1.10.10.60 1 52 1.6E-19 T 29-03-2018 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 SUPERFAMILY SSF46689 2 77 2.86E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS15990 9e7d836a3096c824323088facda5ef3f 220 SUPERFAMILY SSF48498 74 182 7.34E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS15370 ac667eb85cbb280c772a13ce1cb03ec5 172 Gene3D G3DSA:3.10.129.10 19 161 2.2E-34 T 29-03-2018 A616_RS15370 ac667eb85cbb280c772a13ce1cb03ec5 172 SUPERFAMILY SSF54637 45 160 2.8E-34 T 29-03-2018 IPR029069 HotDog domain A616_RS15370 ac667eb85cbb280c772a13ce1cb03ec5 172 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 50 159 5.8E-23 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A616_RS15370 ac667eb85cbb280c772a13ce1cb03ec5 172 Pfam PF03061 Thioesterase superfamily 79 153 8.1E-18 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS02750 7aa6bffb940e97889c9bfe28ef5d37ac 182 Pfam PF10646 Sporulation and spore germination 57 165 5.5E-12 T 29-03-2018 IPR019606 GerMN domain A616_RS02750 7aa6bffb940e97889c9bfe28ef5d37ac 182 Gene3D G3DSA:3.40.190.10 1 164 2.6E-7 T 29-03-2018 A616_RS02750 7aa6bffb940e97889c9bfe28ef5d37ac 182 SMART SM00909 84 169 2.6E-4 T 29-03-2018 IPR019606 GerMN domain A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 226 2.2E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 Gene3D G3DSA:3.40.50.2300 2 126 3.7E-34 T 29-03-2018 A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 Gene3D G3DSA:1.10.10.10 127 228 3.5E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 Pfam PF00072 Response regulator receiver domain 5 115 1.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 SMART SM00862 151 226 7.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 SMART SM00448 3 114 1.1E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS28175 13e6c184a063377fbf36e9cce4eec378 228 SUPERFAMILY SSF52172 4 181 1.08E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Gene3D G3DSA:1.10.10.60 484 569 5.0E-18 T 29-03-2018 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 100 214 4.7E-9 T 29-03-2018 IPR000014 PAS domain A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 328 343 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 SUPERFAMILY SSF46689 455 569 7.17E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Gene3D G3DSA:3.30.450.20 97 240 1.2E-21 T 29-03-2018 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Gene3D G3DSA:1.10.8.60 415 483 1.5E-24 T 29-03-2018 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 SMART SM00382 261 406 2.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Pfam PF13426 PAS domain 113 206 8.1E-11 T 29-03-2018 IPR000014 PAS domain A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 549 569 6.3E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 532 549 6.3E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Pfam PF00158 Sigma-54 interaction domain 242 408 1.9E-71 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Gene3D G3DSA:3.40.50.300 241 414 8.9E-26 T 29-03-2018 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 SUPERFAMILY SSF55785 99 205 2.44E-14 T 29-03-2018 IPR000014 PAS domain A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 SMART SM00091 102 167 1.4E-5 T 29-03-2018 IPR000014 PAS domain A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 265 278 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 Pfam PF02954 Bacterial regulatory protein, Fis family 530 566 9.5E-15 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 SUPERFAMILY SSF52540 241 486 2.17E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05270 547c21b7706a17e365bb2fd4ec34d21e 576 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 455 464 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS00625 7808d1799ac921210dae94db9699de36 256 SUPERFAMILY SSF51556 2 254 1.71E-96 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS00625 7808d1799ac921210dae94db9699de36 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A616_RS00625 7808d1799ac921210dae94db9699de36 256 PIRSF PIRSF005902 1 256 1.1E-85 T 29-03-2018 IPR001130 TatD family GO:0016788 A616_RS00625 7808d1799ac921210dae94db9699de36 256 Pfam PF01026 TatD related DNase 5 252 3.0E-89 T 29-03-2018 IPR001130 TatD family GO:0016788 A616_RS00625 7808d1799ac921210dae94db9699de36 256 Gene3D G3DSA:3.20.20.140 1 256 1.4E-95 T 29-03-2018 A616_RS00625 7808d1799ac921210dae94db9699de36 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 5.6E-95 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A616_RS20690 f782ab4235c6ffad2b924dd2f13f4bed 285 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 283 6.0E-84 T 29-03-2018 IPR003797 DegV A616_RS20690 f782ab4235c6ffad2b924dd2f13f4bed 285 Gene3D G3DSA:3.30.1180.10 157 283 1.0E-40 T 29-03-2018 A616_RS20690 f782ab4235c6ffad2b924dd2f13f4bed 285 Gene3D G3DSA:2.20.28.50 28 53 1.3E-12 T 29-03-2018 A616_RS20690 f782ab4235c6ffad2b924dd2f13f4bed 285 Gene3D G3DSA:3.40.50.10440 54 154 1.2E-32 T 29-03-2018 A616_RS20690 f782ab4235c6ffad2b924dd2f13f4bed 285 SUPERFAMILY SSF82549 1 284 1.1E-84 T 29-03-2018 A616_RS20690 f782ab4235c6ffad2b924dd2f13f4bed 285 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 281 1.5E-94 T 29-03-2018 IPR003797 DegV A616_RS05645 5d644d216758ccb113593754d61c842d 415 Gene3D G3DSA:3.40.1020.10 226 415 1.1E-36 T 29-03-2018 A616_RS05645 5d644d216758ccb113593754d61c842d 415 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 309 1.4E-78 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS05645 5d644d216758ccb113593754d61c842d 415 Gene3D G3DSA:3.40.50.1100 12 174 9.3E-42 T 29-03-2018 A616_RS05645 5d644d216758ccb113593754d61c842d 415 SUPERFAMILY SSF55021 332 410 1.14E-11 T 29-03-2018 A616_RS05645 5d644d216758ccb113593754d61c842d 415 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 322 413 5.5E-27 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A616_RS05645 5d644d216758ccb113593754d61c842d 415 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A616_RS05645 5d644d216758ccb113593754d61c842d 415 SUPERFAMILY SSF53686 7 359 4.71E-100 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS05645 5d644d216758ccb113593754d61c842d 415 TIGRFAM TIGR02079 THD1: threonine dehydratase 8 415 7.3E-199 T 29-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Gene3D G3DSA:3.30.450.40 300 465 3.5E-14 T 29-03-2018 IPR029016 GAF domain-like A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 697 808 1.4E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Pfam PF00072 Response regulator receiver domain 834 943 4.6E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SMART SM00065 317 457 0.0032 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SUPERFAMILY SSF47384 574 654 3.34E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SUPERFAMILY SSF55781 297 455 1.07E-14 T 29-03-2018 IPR029016 GAF domain-like A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SUPERFAMILY SSF158472 214 261 7.59E-6 T 29-03-2018 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Gene3D G3DSA:1.10.287.130 594 647 9.1E-20 T 29-03-2018 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SUPERFAMILY SSF55785 451 577 2.93E-7 T 29-03-2018 IPR000014 PAS domain A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Gene3D G3DSA:3.30.450.20 466 593 1.9E-11 T 29-03-2018 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SUPERFAMILY SSF55874 642 810 5.63E-50 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Gene3D G3DSA:3.40.50.2300 824 956 5.3E-24 T 29-03-2018 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Gene3D G3DSA:3.30.565.10 648 809 1.0E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SMART SM00387 697 809 3.5E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SUPERFAMILY SSF52172 833 952 1.71E-24 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SMART SM00448 832 943 1.8E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Gene3D G3DSA:1.20.1000.10 38 299 2.0E-4 T 29-03-2018 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 SMART SM00388 587 653 3.8E-25 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 793 806 6.0E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 734 748 6.0E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 752 762 6.0E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 769 787 6.0E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27970 3fe670a52cd30f37c3eae5900209e611 962 Pfam PF00512 His Kinase A (phospho-acceptor) domain 587 653 1.4E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 SUPERFAMILY SSF50331 237 360 4.37E-24 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 Gene3D G3DSA:2.40.50.140 290 345 6.1E-12 T 29-03-2018 A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 SUPERFAMILY SSF52540 4 243 7.64E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 Gene3D G3DSA:3.40.50.300 2 240 4.6E-72 T 29-03-2018 A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 Pfam PF08402 TOBE domain 277 352 3.3E-6 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 SMART SM00382 28 211 2.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 Gene3D G3DSA:2.40.50.100 241 289 6.9E-4 T 29-03-2018 A616_RS31370 e8f4a4276cfcf96dcfccae44191b73c1 365 Pfam PF00005 ABC transporter 20 161 6.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS22625 bc446d3bc94ef78bb2057fbf0a0dd79f 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 9 63 6.4E-24 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A616_RS22625 bc446d3bc94ef78bb2057fbf0a0dd79f 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 24 33 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS22625 bc446d3bc94ef78bb2057fbf0a0dd79f 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 42 56 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 SMART SM00862 147 223 6.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 Gene3D G3DSA:1.10.10.10 119 229 4.0E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 SUPERFAMILY SSF46894 126 224 2.35E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 SUPERFAMILY SSF52172 2 124 2.7E-40 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 Gene3D G3DSA:3.40.50.2300 1 118 3.3E-36 T 29-03-2018 A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 SMART SM00448 2 112 2.7E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS14555 4792bcdf7804f3a9867037d7d68aad59 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 4.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS24000 cde218083d6b3abff124285cb7115471 470 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 36 303 3.8E-63 T 29-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A616_RS24000 cde218083d6b3abff124285cb7115471 470 SUPERFAMILY SSF53335 4 303 1.32E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS24000 cde218083d6b3abff124285cb7115471 470 Gene3D G3DSA:3.40.50.150 89 312 3.2E-60 T 29-03-2018 A616_RS24000 cde218083d6b3abff124285cb7115471 470 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 5 93 2.5E-33 T 29-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A616_RS24000 cde218083d6b3abff124285cb7115471 470 Gene3D G3DSA:3.30.70.1170 24 88 2.0E-19 T 29-03-2018 A616_RS24000 cde218083d6b3abff124285cb7115471 470 Pfam PF01189 16S rRNA methyltransferase RsmB/F 98 302 1.8E-49 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 423 469 8.6E-21 T 29-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 339 404 3.7E-22 T 29-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 174 185 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 79 93 2.0E-26 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 175 187 2.0E-26 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 286 303 2.0E-26 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 108 118 2.0E-26 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS24000 cde218083d6b3abff124285cb7115471 470 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 241 2.0E-26 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS08095 9c1ecb6b4a048ff1740fd848e92012bf 377 SMART SM00471 131 267 2.0E-9 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS08095 9c1ecb6b4a048ff1740fd848e92012bf 377 SUPERFAMILY SSF109604 119 297 5.56E-32 T 29-03-2018 A616_RS08095 9c1ecb6b4a048ff1740fd848e92012bf 377 Pfam PF01966 HD domain 136 256 4.3E-13 T 29-03-2018 IPR006674 HD domain A616_RS08095 9c1ecb6b4a048ff1740fd848e92012bf 377 Gene3D G3DSA:1.10.3210.10 55 301 1.0E-40 T 29-03-2018 A616_RS08095 9c1ecb6b4a048ff1740fd848e92012bf 377 TIGRFAM TIGR00277 HDIG: HDIG domain 133 210 1.6E-8 T 29-03-2018 IPR006675 HDIG domain A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 Pfam PF07687 Peptidase dimerisation domain 183 273 1.2E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 PIRSF PIRSF005962 1 382 1.3E-93 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 SUPERFAMILY SSF53187 291 378 5.29E-60 T 29-03-2018 A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 SUPERFAMILY SSF53187 7 192 5.29E-60 T 29-03-2018 A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 364 5.2E-88 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 Pfam PF01546 Peptidase family M20/M25/M40 76 375 5.8E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 Gene3D G3DSA:3.40.630.10 1 274 2.0E-50 T 29-03-2018 A616_RS02130 bba964a457d7660373a2c7d4d015514f 383 SUPERFAMILY SSF55031 184 283 1.14E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS30760 69fbca859bfb32d813a7d3e903b84531 497 TIGRFAM TIGR02518 EutH_ACDH: acetaldehyde dehydrogenase (acetylating) 4 495 1.6E-196 T 29-03-2018 IPR013357 Acetaldehyde dehydrogenase, acetylating A616_RS30760 69fbca859bfb32d813a7d3e903b84531 497 Gene3D G3DSA:3.40.605.10 4 233 1.8E-33 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS30760 69fbca859bfb32d813a7d3e903b84531 497 Gene3D G3DSA:3.40.309.10 234 406 7.9E-24 T 29-03-2018 A616_RS30760 69fbca859bfb32d813a7d3e903b84531 497 SUPERFAMILY SSF53720 9 449 2.75E-80 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS30760 69fbca859bfb32d813a7d3e903b84531 497 Pfam PF00171 Aldehyde dehydrogenase family 11 272 1.3E-25 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS03625 2f97f478548a3bba49f18f11e8973a77 179 Pfam PF11127 Protein of unknown function (DUF2892) 1 67 2.2E-17 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 A616_RS01770 c4b8d3775ddfe0c0f56b5c66924beec7 865 Pfam PF12704 MacB-like periplasmic core domain 19 199 4.0E-6 T 29-03-2018 IPR025857 MacB-like periplasmic core domain A616_RS01770 c4b8d3775ddfe0c0f56b5c66924beec7 865 Pfam PF02687 FtsX-like permease family 320 419 1.1E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS01770 c4b8d3775ddfe0c0f56b5c66924beec7 865 Pfam PF02687 FtsX-like permease family 764 852 1.5E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS21905 c0b87f6fef5522a392b8f2b680c407a0 211 Gene3D G3DSA:1.10.10.10 1 81 1.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21905 c0b87f6fef5522a392b8f2b680c407a0 211 SUPERFAMILY SSF46785 9 189 1.6E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21905 c0b87f6fef5522a392b8f2b680c407a0 211 Pfam PF13601 Winged helix DNA-binding domain 13 80 3.1E-8 T 29-03-2018 IPR027395 Winged helix DNA-binding domain A616_RS01805 cb87ed5811c394213d177029322713c4 193 Gene3D G3DSA:1.10.10.60 1 58 2.3E-18 T 29-03-2018 A616_RS01805 cb87ed5811c394213d177029322713c4 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS01805 cb87ed5811c394213d177029322713c4 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS01805 cb87ed5811c394213d177029322713c4 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.9E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS01805 cb87ed5811c394213d177029322713c4 193 Gene3D G3DSA:1.10.357.10 59 193 1.1E-20 T 29-03-2018 A616_RS01805 cb87ed5811c394213d177029322713c4 193 SUPERFAMILY SSF48498 78 192 2.34E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS01805 cb87ed5811c394213d177029322713c4 193 SUPERFAMILY SSF46689 2 82 4.72E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS14545 0e11169909df0362144a4d9a4ed1a8fb 164 SUPERFAMILY SSF55136 2 161 2.62E-23 T 29-03-2018 A616_RS14545 0e11169909df0362144a4d9a4ed1a8fb 164 Pfam PF14526 Integron-associated effector binding protein 5 161 1.1E-34 T 29-03-2018 IPR029441 Integron-associated effector binding protein A616_RS14545 0e11169909df0362144a4d9a4ed1a8fb 164 Gene3D G3DSA:3.20.80.10 1 162 3.3E-44 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS14545 0e11169909df0362144a4d9a4ed1a8fb 164 SMART SM00871 2 162 1.6E-36 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS16260 5fef3a28f074e316965686fd8b94cf13 153 PRINTS PR00502 NUDIX hydrolase family signature 42 56 1.7E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS16260 5fef3a28f074e316965686fd8b94cf13 153 PRINTS PR00502 NUDIX hydrolase family signature 56 71 1.7E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS16260 5fef3a28f074e316965686fd8b94cf13 153 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS16260 5fef3a28f074e316965686fd8b94cf13 153 Gene3D G3DSA:3.90.79.10 1 148 1.9E-22 T 29-03-2018 A616_RS16260 5fef3a28f074e316965686fd8b94cf13 153 Pfam PF00293 NUDIX domain 19 140 1.7E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS16260 5fef3a28f074e316965686fd8b94cf13 153 SUPERFAMILY SSF55811 16 147 6.5E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS23815 a6e186d67eed4fa448718dbb8ade6750 244 Pfam PF00005 ABC transporter 17 169 1.0E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23815 a6e186d67eed4fa448718dbb8ade6750 244 SUPERFAMILY SSF52540 1 239 7.14E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23815 a6e186d67eed4fa448718dbb8ade6750 244 PIRSF PIRSF039085 1 244 1.6E-118 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS23815 a6e186d67eed4fa448718dbb8ade6750 244 SMART SM00382 26 217 8.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23815 a6e186d67eed4fa448718dbb8ade6750 244 Gene3D G3DSA:3.40.50.300 1 244 6.4E-79 T 29-03-2018 A616_RS23815 a6e186d67eed4fa448718dbb8ade6750 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25145 8d3f2b9192ef68074b386d52a6ef7f4a 341 SUPERFAMILY SSF54506 1 332 5.07E-119 T 29-03-2018 A616_RS25145 8d3f2b9192ef68074b386d52a6ef7f4a 341 Gene3D G3DSA:3.10.310.10 154 310 8.6E-57 T 29-03-2018 A616_RS25145 8d3f2b9192ef68074b386d52a6ef7f4a 341 PIRSF PIRSF029792 1 335 1.1E-141 T 29-03-2018 IPR008794 Proline racemase family A616_RS25145 8d3f2b9192ef68074b386d52a6ef7f4a 341 Pfam PF05544 Proline racemase 10 332 2.2E-126 T 29-03-2018 IPR008794 Proline racemase family A616_RS25145 8d3f2b9192ef68074b386d52a6ef7f4a 341 Gene3D G3DSA:3.10.310.10 1 153 7.9E-37 T 29-03-2018 A616_RS04660 11f5fb3be6a07c0fa5a7a7a3f10efe49 290 Pfam PF01261 Xylose isomerase-like TIM barrel 25 223 5.0E-22 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS04660 11f5fb3be6a07c0fa5a7a7a3f10efe49 290 SUPERFAMILY SSF51658 2 289 2.9E-45 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS04660 11f5fb3be6a07c0fa5a7a7a3f10efe49 290 Gene3D G3DSA:3.20.20.150 1 290 2.9E-50 T 29-03-2018 A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 SUPERFAMILY SSF52374 4 284 8.04E-110 T 29-03-2018 A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 Gene3D G3DSA:3.40.50.620 1 179 9.1E-80 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 31 79 4.3E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 6 284 2.0E-106 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 Gene3D G3DSA:3.30.1300.10 180 288 4.7E-32 T 29-03-2018 A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 Pfam PF02569 Pantoate-beta-alanine ligase 9 283 2.6E-109 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A616_RS13955 2ca3d34ef71e8de5e8e2f30c3fc6795e 288 Hamap MF_00158 Pantothenate synthetase [panC]. 7 285 41.196 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A616_RS10570 788c913f925c4a64adce43c3402f9b8f 194 SUPERFAMILY SSF55890 11 187 2.48E-22 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A616_RS10570 788c913f925c4a64adce43c3402f9b8f 194 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 8 65 4.8E-19 T 29-03-2018 A616_RS10570 788c913f925c4a64adce43c3402f9b8f 194 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 70 185 1.6E-28 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal A616_RS10570 788c913f925c4a64adce43c3402f9b8f 194 Gene3D G3DSA:3.30.565.30 68 186 6.3E-22 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal A616_RS10570 788c913f925c4a64adce43c3402f9b8f 194 Gene3D G3DSA:1.10.287.130 9 63 1.9E-9 T 29-03-2018 A616_RS10570 788c913f925c4a64adce43c3402f9b8f 194 SMART SM01317 67 186 1.7E-47 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal A616_RS19240 02b4c361accc02067712286cf6fb3a30 265 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 15 261 6.6E-115 T 29-03-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase A616_RS19240 02b4c361accc02067712286cf6fb3a30 265 SUPERFAMILY SSF53335 51 228 3.38E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS19240 02b4c361accc02067712286cf6fb3a30 265 Gene3D G3DSA:3.40.50.150 69 258 2.5E-37 T 29-03-2018 A616_RS19240 02b4c361accc02067712286cf6fb3a30 265 Pfam PF05175 Methyltransferase small domain 75 197 1.6E-11 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A616_RS19240 02b4c361accc02067712286cf6fb3a30 265 Gene3D G3DSA:1.10.8.10 19 68 3.3E-7 T 29-03-2018 A616_RS19240 02b4c361accc02067712286cf6fb3a30 265 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 42 238 1.5E-38 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 SMART SM00895 98 220 9.0E-22 T 29-03-2018 IPR011711 GntR, C-terminal A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 SUPERFAMILY SSF46785 3 77 8.34E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 SMART SM00345 14 73 5.4E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 Gene3D G3DSA:1.20.120.530 92 222 2.2E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 Pfam PF07729 FCD domain 98 219 3.7E-26 T 29-03-2018 IPR011711 GntR, C-terminal A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 2.1E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 SUPERFAMILY SSF48008 97 221 1.23E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A616_RS07930 083d3b89aec6fcd58597cde663e4fcfa 223 Gene3D G3DSA:1.10.10.10 1 75 9.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 4.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 4.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 4.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 Gene3D G3DSA:1.10.10.10 1 78 5.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 SUPERFAMILY SSF46785 2 84 1.85E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 61 9.6E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 SUPERFAMILY SSF53850 91 286 1.01E-28 T 29-03-2018 A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 Pfam PF03466 LysR substrate binding domain 88 286 6.6E-29 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 Gene3D G3DSA:3.40.190.10 79 175 4.6E-16 T 29-03-2018 A616_RS24840 1c39c5825085db4e7cd979e2b1523d61 286 Gene3D G3DSA:3.40.190.10 176 262 2.3E-11 T 29-03-2018 A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 SUPERFAMILY SSF90123 3 311 7.46E-76 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 SMART SM00382 360 563 1.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 Pfam PF00005 ABC transporter 351 498 2.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 Gene3D G3DSA:1.20.1560.10 1 315 5.6E-81 T 29-03-2018 A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 Pfam PF00664 ABC transporter transmembrane region 16 285 4.3E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 SUPERFAMILY SSF52540 329 572 2.45E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15725 df3dcf4de4c6fd89fe4bc36f52cdf1fb 579 Gene3D G3DSA:3.40.50.300 318 578 1.6E-71 T 29-03-2018 A616_RS04205 417ac66b31c5a0aa70b185b43648d2ea 169 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 42 156 1.1E-16 T 29-03-2018 IPR018958 Knr4/Smi1-like domain A616_RS04205 417ac66b31c5a0aa70b185b43648d2ea 169 Gene3D G3DSA:3.40.1580.10 31 169 2.8E-22 T 29-03-2018 A616_RS04205 417ac66b31c5a0aa70b185b43648d2ea 169 SMART SM00860 42 157 5.0E-9 T 29-03-2018 IPR018958 Knr4/Smi1-like domain A616_RS04205 417ac66b31c5a0aa70b185b43648d2ea 169 SUPERFAMILY SSF160631 27 168 4.19E-22 T 29-03-2018 A616_RS31840 681d864e04adb96368da08c554ca587e 596 Pfam PF00072 Response regulator receiver domain 386 496 1.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31840 681d864e04adb96368da08c554ca587e 596 SUPERFAMILY SSF52172 382 514 1.18E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31840 681d864e04adb96368da08c554ca587e 596 SMART SM00387 286 376 1.7E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31840 681d864e04adb96368da08c554ca587e 596 Pfam PF07730 Histidine kinase 183 245 7.6E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS31840 681d864e04adb96368da08c554ca587e 596 SUPERFAMILY SSF55874 253 373 1.03E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31840 681d864e04adb96368da08c554ca587e 596 Gene3D G3DSA:3.30.565.10 247 382 1.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31840 681d864e04adb96368da08c554ca587e 596 Gene3D G3DSA:1.10.10.10 508 596 5.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31840 681d864e04adb96368da08c554ca587e 596 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 373 7.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31840 681d864e04adb96368da08c554ca587e 596 Gene3D G3DSA:3.40.50.2300 383 507 6.0E-35 T 29-03-2018 A616_RS31840 681d864e04adb96368da08c554ca587e 596 Pfam PF00196 Bacterial regulatory proteins, luxR family 536 590 1.4E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31840 681d864e04adb96368da08c554ca587e 596 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 550 566 5.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31840 681d864e04adb96368da08c554ca587e 596 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 566 578 5.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31840 681d864e04adb96368da08c554ca587e 596 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 536 550 5.5E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31840 681d864e04adb96368da08c554ca587e 596 SMART SM00421 533 590 1.1E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31840 681d864e04adb96368da08c554ca587e 596 SMART SM00448 383 496 1.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31840 681d864e04adb96368da08c554ca587e 596 SUPERFAMILY SSF46894 518 593 1.39E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS27455 8d7d33e77df594270b5054aa943a1643 247 SUPERFAMILY SSF52540 5 242 8.77E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27455 8d7d33e77df594270b5054aa943a1643 247 Pfam PF00005 ABC transporter 21 169 3.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27455 8d7d33e77df594270b5054aa943a1643 247 SMART SM00382 30 219 1.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27455 8d7d33e77df594270b5054aa943a1643 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 241 5.8E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A616_RS27455 8d7d33e77df594270b5054aa943a1643 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS27455 8d7d33e77df594270b5054aa943a1643 247 Gene3D G3DSA:3.40.50.300 2 246 4.1E-60 T 29-03-2018 A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 SUPERFAMILY SSF51735 4 274 1.14E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 Gene3D G3DSA:3.40.50.720 4 267 1.8E-65 T 29-03-2018 A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 Pfam PF00106 short chain dehydrogenase 6 199 1.5E-52 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS27570 b38a6f6e48c5ccd841baf531a8b76200 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.4E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26775 3df3df9b50c45a70dfa4d1b2b2b915cd 432 Pfam PF01458 Uncharacterized protein family (UPF0051) 183 406 3.2E-62 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A616_RS26775 3df3df9b50c45a70dfa4d1b2b2b915cd 432 SUPERFAMILY SSF101960 13 431 1.7E-108 T 29-03-2018 A616_RS26775 3df3df9b50c45a70dfa4d1b2b2b915cd 432 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 149 423 2.6E-75 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 PIRSF PIRSF001363 6 535 3.1E-256 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 ProSitePatterns PS00510 Malate synthase signature. 269 284 - T 29-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 Gene3D G3DSA:3.20.20.360 82 416 1.2E-115 T 29-03-2018 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 SUPERFAMILY SSF51645 8 535 7.32E-195 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 Gene3D G3DSA:1.20.1220.12 417 535 6.1E-46 T 29-03-2018 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 26 535 4.6E-246 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A616_RS00240 f1ac4160ae64db3d4ca94f38d7b15e71 535 Pfam PF01274 Malate synthase 14 534 4.6E-209 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A616_RS05425 f50cd18d222d8718d43a22f6cb3e74d1 281 SUPERFAMILY SSF53850 1 271 2.07E-76 T 29-03-2018 A616_RS05425 f50cd18d222d8718d43a22f6cb3e74d1 281 Pfam PF02621 Menaquinone biosynthesis 1 267 1.9E-81 T 29-03-2018 IPR003773 Menaquinone biosynthesis enzyme A616_RS05425 f50cd18d222d8718d43a22f6cb3e74d1 281 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 1 272 34.286 T 29-03-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 A616_RS05425 f50cd18d222d8718d43a22f6cb3e74d1 281 Gene3D G3DSA:3.40.190.10 178 278 1.9E-12 T 29-03-2018 A616_RS05425 f50cd18d222d8718d43a22f6cb3e74d1 281 Gene3D G3DSA:3.40.190.10 1 177 1.1E-79 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 Gene3D G3DSA:3.50.50.60 2 141 6.8E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 292 8.3E-84 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 Gene3D G3DSA:3.50.50.60 257 325 2.5E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 Gene3D G3DSA:3.50.50.60 142 256 3.1E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 130 3.5E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 157 181 3.5E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 267 3.5E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.5E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 283 301 3.5E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 SUPERFAMILY SSF51905 1 320 1.27E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 139 2.9E-16 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 2.9E-16 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.9E-16 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 2.9E-16 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 2.9E-16 T 29-03-2018 A616_RS14485 342267ad551f8644e224c55b9fe16995 325 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 3 321 2.5E-138 T 29-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA A616_RS01495 f2447ec6c8790f452c94cfa2cf6033e1 146 Gene3D G3DSA:3.100.10.10 42 146 1.4E-30 T 29-03-2018 A616_RS01495 f2447ec6c8790f452c94cfa2cf6033e1 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 21.337 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A616_RS01495 f2447ec6c8790f452c94cfa2cf6033e1 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.1E-53 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01495 f2447ec6c8790f452c94cfa2cf6033e1 146 SUPERFAMILY SSF52080 4 143 2.35E-48 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P A616_RS01495 f2447ec6c8790f452c94cfa2cf6033e1 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01495 f2447ec6c8790f452c94cfa2cf6033e1 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 6.2E-36 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 SUPERFAMILY SSF88946 2 98 3.14E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 SUPERFAMILY SSF88659 107 176 1.1E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 Pfam PF04542 Sigma-70 region 2 25 90 1.0E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 Gene3D G3DSA:1.10.1740.10 1 106 2.7E-22 T 29-03-2018 A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 Gene3D G3DSA:1.10.10.10 119 181 7.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 176 7.4E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04855 67e45436a768f40ba4bfae36380f4b86 190 Pfam PF08281 Sigma-70, region 4 126 172 4.1E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 256 375 2.1E-7 T 29-03-2018 IPR000014 PAS domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SUPERFAMILY SSF55874 431 600 1.44E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SMART SM00091 260 328 0.001 T 29-03-2018 IPR000014 PAS domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Pfam PF00512 His Kinase A (phospho-acceptor) domain 376 441 7.6E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Gene3D G3DSA:3.30.450.20 33 174 6.8E-22 T 29-03-2018 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Gene3D G3DSA:3.30.450.20 257 380 6.2E-21 T 29-03-2018 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SUPERFAMILY SSF158472 201 251 4.58E-11 T 29-03-2018 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Pfam PF13426 PAS domain 271 368 5.3E-7 T 29-03-2018 IPR000014 PAS domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SMART SM00304 201 253 5.0E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 601 2.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Gene3D G3DSA:3.30.565.10 446 606 1.4E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 7.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 7.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 7.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 7.8E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SUPERFAMILY SSF55785 248 367 2.44E-13 T 29-03-2018 IPR000014 PAS domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SMART SM00388 375 442 7.4E-23 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Pfam PF00672 HAMP domain 201 250 4.5E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SMART SM00387 488 602 5.0E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 Gene3D G3DSA:1.10.287.130 381 438 9.3E-20 T 29-03-2018 A616_RS32120 c1428fcd02e1fa2751993a9ec846927b 607 SUPERFAMILY SSF47384 361 442 1.02E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS21390 097e3682e06dbdbc0bd8095a72fdd848 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 255 8.2E-69 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS21390 097e3682e06dbdbc0bd8095a72fdd848 257 SUPERFAMILY SSF52096 3 256 4.13E-87 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS21390 097e3682e06dbdbc0bd8095a72fdd848 257 Gene3D G3DSA:3.90.226.10 2 214 2.7E-76 T 29-03-2018 A616_RS21390 097e3682e06dbdbc0bd8095a72fdd848 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS21390 097e3682e06dbdbc0bd8095a72fdd848 257 Gene3D G3DSA:1.10.12.10 215 257 3.9E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 SUPERFAMILY SSF48179 206 314 8.08E-17 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Pfam PF00378 Enoyl-CoA hydratase/isomerase 494 628 1.8E-11 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Gene3D G3DSA:3.90.226.10 481 800 4.4E-40 T 29-03-2018 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 SUPERFAMILY SSF48179 364 454 1.45E-15 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Gene3D G3DSA:3.40.50.720 1 205 6.9E-39 T 29-03-2018 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 307 1.7E-8 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 386 420 3.8E-5 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 SUPERFAMILY SSF52096 488 799 9.33E-41 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Gene3D G3DSA:1.10.1040.10 370 480 1.4E-12 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 205 2.0E-42 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 SUPERFAMILY SSF51735 4 206 5.21E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26965 4d80e3efdb344760d3e64501ba64928a 802 Gene3D G3DSA:1.10.1040.10 206 313 7.7E-14 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 Gene3D G3DSA:3.20.20.80 138 543 1.3E-57 T 29-03-2018 A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 Pfam PF00704 Glycosyl hydrolases family 18 280 520 5.7E-29 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 SMART SM00636 229 522 3.2E-15 T 29-03-2018 IPR011583 Chitinase II GO:0008061 A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 ProSitePatterns PS01095 Chitinases family 18 active site. 326 334 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 SUPERFAMILY SSF51445 494 538 1.8E-46 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 SUPERFAMILY SSF51445 244 437 1.8E-46 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 Pfam PF00395 S-layer homology domain 46 86 1.6E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 Pfam PF00395 S-layer homology domain 168 209 0.0061 T 29-03-2018 IPR001119 S-layer homology domain A616_RS14480 d4d8e33d9df2bff18342216e1422ef5c 543 Pfam PF00395 S-layer homology domain 106 148 6.0E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS04645 da099d9d03099b5f860d5cf4ad56b708 400 SUPERFAMILY SSF46785 9 74 8.04E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04645 da099d9d03099b5f860d5cf4ad56b708 400 Gene3D G3DSA:3.30.420.40 221 373 1.3E-36 T 29-03-2018 A616_RS04645 da099d9d03099b5f860d5cf4ad56b708 400 Gene3D G3DSA:1.10.10.10 16 77 1.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04645 da099d9d03099b5f860d5cf4ad56b708 400 Gene3D G3DSA:3.30.420.40 79 220 2.1E-27 T 29-03-2018 A616_RS04645 da099d9d03099b5f860d5cf4ad56b708 400 SUPERFAMILY SSF53067 83 393 2.19E-50 T 29-03-2018 A616_RS04645 da099d9d03099b5f860d5cf4ad56b708 400 Pfam PF00480 ROK family 84 392 3.1E-54 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 SUPERFAMILY SSF52540 6 255 2.42E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 Pfam PF00005 ABC transporter 34 184 2.9E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 SMART SM00382 42 234 5.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 Gene3D G3DSA:3.40.50.300 3 323 3.7E-78 T 29-03-2018 A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 3.6E-30 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28605 74aa443490859a1116bb5b6c075d808e 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 1.3E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 Gene3D G3DSA:3.40.50.720 2 263 4.3E-50 T 29-03-2018 A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 Pfam PF00106 short chain dehydrogenase 8 192 6.5E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15025 331dec298474a5657d1dbc371ddf0344 263 SUPERFAMILY SSF51735 1 259 9.65E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26770 acab715365d3c703be1651e506de6791 408 SUPERFAMILY SSF53383 2 399 1.84E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS26770 acab715365d3c703be1651e506de6791 408 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 4 404 3.7E-184 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A616_RS26770 acab715365d3c703be1651e506de6791 408 Gene3D G3DSA:3.40.640.10 33 280 1.9E-65 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS26770 acab715365d3c703be1651e506de6791 408 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A616_RS26770 acab715365d3c703be1651e506de6791 408 PIRSF PIRSF005572 20 405 2.1E-49 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A616_RS26770 acab715365d3c703be1651e506de6791 408 Gene3D G3DSA:3.90.1150.10 281 399 3.0E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS26770 acab715365d3c703be1651e506de6791 408 Pfam PF00266 Aminotransferase class-V 23 392 9.6E-157 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS22015 5bc8a86d8f275c02e84a0d80dcaedb3c 438 SUPERFAMILY SSF52777 197 429 1.45E-6 T 29-03-2018 A616_RS22015 5bc8a86d8f275c02e84a0d80dcaedb3c 438 SUPERFAMILY SSF52777 34 170 7.78E-11 T 29-03-2018 A616_RS22015 5bc8a86d8f275c02e84a0d80dcaedb3c 438 Pfam PF00668 Condensation domain 33 166 2.8E-8 T 29-03-2018 IPR001242 Condensation domain A616_RS22015 5bc8a86d8f275c02e84a0d80dcaedb3c 438 Gene3D G3DSA:3.30.559.10 12 184 3.8E-9 T 29-03-2018 A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 SUPERFAMILY SSF53163 4 366 1.1E-117 T 29-03-2018 IPR023430 Peptidase HybD-like domain A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 PIRSF PIRSF019549 3 366 1.6E-154 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 366 4.0E-119 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 366 8.6E-149 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 Pfam PF03418 Germination protease 17 365 7.7E-169 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 Gene3D G3DSA:3.40.50.1450 8 362 5.3E-121 T 29-03-2018 IPR023430 Peptidase HybD-like domain A616_RS11290 b4f195bd15dc51fd71949f358253d8ab 366 Hamap MF_00626 Germination protease [gpr]. 1 366 151.356 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 A616_RS01545 5e838b4f3083a12a2c62eaefda2f18fd 283 SMART SM00382 36 222 3.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01545 5e838b4f3083a12a2c62eaefda2f18fd 283 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS01545 5e838b4f3083a12a2c62eaefda2f18fd 283 SUPERFAMILY SSF52540 6 237 2.01E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01545 5e838b4f3083a12a2c62eaefda2f18fd 283 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 9 277 1.6E-117 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 A616_RS01545 5e838b4f3083a12a2c62eaefda2f18fd 283 Gene3D G3DSA:3.40.50.300 2 245 3.7E-64 T 29-03-2018 A616_RS01545 5e838b4f3083a12a2c62eaefda2f18fd 283 Pfam PF00005 ABC transporter 27 174 9.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS29990 d2cf3c60101a31cb62c31bf04a17870c 382 SUPERFAMILY SSF53756 3 370 1.49E-136 T 29-03-2018 A616_RS29990 d2cf3c60101a31cb62c31bf04a17870c 382 Gene3D G3DSA:3.40.50.2000 1 217 1.3E-84 T 29-03-2018 A616_RS29990 d2cf3c60101a31cb62c31bf04a17870c 382 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 367 1.5E-160 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A616_RS29990 d2cf3c60101a31cb62c31bf04a17870c 382 Gene3D G3DSA:3.40.50.2000 218 349 1.8E-7 T 29-03-2018 A616_RS29990 d2cf3c60101a31cb62c31bf04a17870c 382 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 364 4.2E-120 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 Hamap MF_00235 Adenylate kinase [adk]. 1 213 52.135 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 PRINTS PR00094 Adenylate kinase signature 160 175 2.1E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 PRINTS PR00094 Adenylate kinase signature 177 191 2.1E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 PRINTS PR00094 Adenylate kinase signature 4 17 2.1E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 PRINTS PR00094 Adenylate kinase signature 81 97 2.1E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 PRINTS PR00094 Adenylate kinase signature 32 46 2.1E-31 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 Pfam PF00406 Adenylate kinase 5 189 1.8E-58 T 29-03-2018 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 SUPERFAMILY SSF52540 3 212 3.48E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 Pfam PF05191 Adenylate kinase, active site lid 127 162 3.3E-18 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 Gene3D G3DSA:3.40.50.300 1 214 3.4E-66 T 29-03-2018 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A616_RS01505 81b690a59612c28fbb336d5254ab601a 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 5.4E-81 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Gene3D G3DSA:3.40.50.10490 240 459 2.6E-70 T 29-03-2018 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Gene3D G3DSA:3.40.50.10490 460 608 3.4E-45 T 29-03-2018 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.234 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Pfam PF13522 Glutamine amidotransferase domain 64 185 1.1E-20 T 29-03-2018 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 2.8E-245 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Pfam PF01380 SIS domain 295 416 6.5E-34 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Pfam PF01380 SIS domain 463 591 2.8E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 Gene3D G3DSA:3.60.20.10 2 239 6.7E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS11915 9a326244d2834efa2de065af92e5521a 610 SUPERFAMILY SSF53697 245 610 1.76E-110 T 29-03-2018 A616_RS11915 9a326244d2834efa2de065af92e5521a 610 SUPERFAMILY SSF56235 2 224 1.63E-68 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 SUPERFAMILY SSF53613 10 262 4.68E-59 T 29-03-2018 IPR029056 Ribokinase-like A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 11 258 6.1E-98 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 2.7E-44 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 2.7E-44 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 2.7E-44 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 2.7E-44 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 2.7E-44 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 2.7E-44 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 Gene3D G3DSA:3.40.1190.20 1 269 1.6E-55 T 29-03-2018 IPR029056 Ribokinase-like A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 PIRSF PIRSF000513 4 268 9.4E-97 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 260 33.873 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS21760 ab5cabcb3cc86dd879684a91d5a4ce49 269 Pfam PF02110 Hydroxyethylthiazole kinase family 11 256 1.6E-95 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 Pfam PF00107 Zinc-binding dehydrogenase 166 248 2.7E-16 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 SUPERFAMILY SSF50129 1 161 9.43E-31 T 29-03-2018 IPR011032 GroES-like A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 SMART SM00829 10 300 4.1E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 Gene3D G3DSA:3.40.50.720 153 235 3.0E-22 T 29-03-2018 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 Pfam PF13602 Zinc-binding dehydrogenase 253 300 1.9E-12 T 29-03-2018 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 116 1.4E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 Gene3D G3DSA:3.90.180.10 236 304 3.9E-7 T 29-03-2018 A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 SUPERFAMILY SSF51735 127 277 5.22E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS08335 36d6fe11b9a2268984c5b0295b2e22e4 304 Gene3D G3DSA:3.90.180.10 1 152 9.1E-39 T 29-03-2018 A616_RS19190 97da4aafeac7acefa13dbf10ea142bc0 125 Pfam PF08000 Bacterial PH domain 3 122 4.1E-53 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain A616_RS19190 97da4aafeac7acefa13dbf10ea142bc0 125 Gene3D G3DSA:2.30.29.50 13 102 2.0E-40 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain A616_RS19190 97da4aafeac7acefa13dbf10ea142bc0 125 SUPERFAMILY SSF50729 6 124 1.11E-47 T 29-03-2018 IPR011993 PH domain-like A616_RS07875 07118a2a9a21d591f3903e0f145c0183 458 Pfam PF14398 YheC/D like ATP-grasp 200 455 4.6E-83 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS07875 07118a2a9a21d591f3903e0f145c0183 458 Gene3D G3DSA:3.30.470.20 302 437 1.0E-13 T 29-03-2018 A616_RS07875 07118a2a9a21d591f3903e0f145c0183 458 SUPERFAMILY SSF56059 223 429 3.74E-13 T 29-03-2018 A616_RS07875 07118a2a9a21d591f3903e0f145c0183 458 Gene3D G3DSA:3.30.1490.20 230 301 5.9E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS06850 9d0652b2c9b09ff56de94efb896138ce 169 Gene3D G3DSA:1.10.10.10 109 167 1.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06850 9d0652b2c9b09ff56de94efb896138ce 169 SUPERFAMILY SSF51206 3 113 2.88E-20 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS06850 9d0652b2c9b09ff56de94efb896138ce 169 Pfam PF00027 Cyclic nucleotide-binding domain 3 85 3.0E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS06850 9d0652b2c9b09ff56de94efb896138ce 169 Pfam PF00325 Bacterial regulatory proteins, crp family 141 161 1.4E-4 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS06850 9d0652b2c9b09ff56de94efb896138ce 169 Gene3D G3DSA:2.60.120.10 1 108 5.4E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.3E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.3E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.3E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 Gene3D G3DSA:3.40.50.2300 1 123 1.3E-33 T 29-03-2018 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 SMART SM00448 2 113 1.4E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 SUPERFAMILY SSF52172 1 128 1.24E-29 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 Pfam PF00072 Response regulator receiver domain 4 113 3.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 SMART SM00421 135 192 5.9E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 191 3.8E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 Gene3D G3DSA:1.10.10.10 124 199 8.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04570 7a1a0f54b81062e5d8c038e8fa26a5d2 199 SUPERFAMILY SSF46894 122 198 2.14E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS24900 6cd02707030f2990b141741313029784 564 Gene3D G3DSA:1.10.10.60 483 535 5.7E-8 T 29-03-2018 A616_RS24900 6cd02707030f2990b141741313029784 564 Pfam PF07905 Purine catabolism regulatory protein-like family 6 123 6.2E-31 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain A616_RS24900 6cd02707030f2990b141741313029784 564 Gene3D G3DSA:3.40.1390.20 2 124 0.0024 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A616_RS24900 6cd02707030f2990b141741313029784 564 Pfam PF13556 PucR C-terminal helix-turn-helix domain 499 557 1.8E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 293 2.9E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 SMART SM00382 35 226 9.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 Pfam PF00005 ABC transporter 27 176 2.6E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 313 2.3E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 Gene3D G3DSA:3.40.50.300 2 316 2.2E-82 T 29-03-2018 A616_RS10195 c8a4237f10d11d0137731357daabdce1 316 SUPERFAMILY SSF52540 5 248 9.71E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24075 bdb5fee769dc6237b85d249c3a28a47a 830 Pfam PF01136 Peptidase family U32 81 306 5.5E-82 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A616_RS24075 bdb5fee769dc6237b85d249c3a28a47a 830 Pfam PF01136 Peptidase family U32 613 810 9.2E-19 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A616_RS24075 bdb5fee769dc6237b85d249c3a28a47a 830 Gene3D G3DSA:3.20.20.70 71 672 3.6E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS24075 bdb5fee769dc6237b85d249c3a28a47a 830 Pfam PF12392 Collagenase 402 520 2.2E-25 T 29-03-2018 IPR020988 Peptidase U32, collagenase A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 SMART SM01403 7 101 2.0E-60 T 29-03-2018 IPR027486 Ribosomal protein S10 domain A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 SUPERFAMILY SSF54999 5 102 8.89E-39 T 29-03-2018 IPR027486 Ribosomal protein S10 domain A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.6E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.075 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 Gene3D G3DSA:3.30.70.600 3 102 6.1E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 8.9E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 8.9E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 8.9E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01395 5af3e9c81a440eecb01c70323d8641bd 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.2E-46 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS13640 d48a61763995d24a95477de1afe4a1db 197 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 22 144 2.0E-30 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 A616_RS13640 d48a61763995d24a95477de1afe4a1db 197 SUPERFAMILY SSF69593 3 195 7.98E-53 T 29-03-2018 A616_RS13640 d48a61763995d24a95477de1afe4a1db 197 Pfam PF01553 Acyltransferase 22 144 2.7E-25 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A616_RS13640 d48a61763995d24a95477de1afe4a1db 197 Gene3D G3DSA:3.40.1130.10 2 197 1.7E-47 T 29-03-2018 A616_RS13640 d48a61763995d24a95477de1afe4a1db 197 SMART SM00563 35 147 2.8E-38 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A616_RS16175 9df5c9ef3a833fcd40029fdeedef2302 379 Pfam PF14286 DHHW protein 125 338 8.1E-38 T 29-03-2018 IPR025945 DHHW protein A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Pfam PF12245 Bacterial Ig-like domain (group 3) 543 555 1.4 T 29-03-2018 IPR022038 Bacterial Ig-like domain A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.10 1214 1304 6.4E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SMART SM00635 1570 1650 5.7E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SMART SM00635 1483 1564 2.6E-10 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SMART SM00635 1313 1390 8.0E-19 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Pfam PF02368 Bacterial Ig-like domain (group 2) 1313 1391 6.0E-19 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Pfam PF02368 Bacterial Ig-like domain (group 2) 1487 1552 8.1E-7 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Pfam PF02368 Bacterial Ig-like domain (group 2) 1571 1638 4.3E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Pfam PF00028 Cadherin domain 227 306 4.7E-8 T 29-03-2018 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 PRINTS PR00205 Cadherin signature 219 248 6.1E-5 T 29-03-2018 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 PRINTS PR00205 Cadherin signature 283 295 6.1E-5 T 29-03-2018 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 PRINTS PR00205 Cadherin signature 295 314 6.1E-5 T 29-03-2018 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 PRINTS PR00205 Cadherin signature 1062 1088 6.1E-5 T 29-03-2018 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1080 1568 1652 2.6E-16 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1080 1397 1480 0.11 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1080 1481 1567 4.5E-17 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.350.10 201 373 2.2E-24 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SMART SM00112 241 314 1.8E-11 T 29-03-2018 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SUPERFAMILY SSF49373 1569 1651 5.73E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SUPERFAMILY SSF49313 216 308 2.28E-13 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SUPERFAMILY SSF49373 1313 1393 2.16E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 776 871 1.3E-6 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 539 620 0.0025 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 872 948 5.4E-4 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 1118 1195 3.5E-5 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 374 462 1.5E-4 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 621 775 1.1E-6 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 1023 1117 8.3E-9 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1310 463 538 4.4E-5 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 Gene3D G3DSA:2.60.40.1080 1310 1396 2.3E-27 T 29-03-2018 A616_RS28680 039eed509ffef742cc55cddd8d180342 1652 SUPERFAMILY SSF49373 1485 1565 1.65E-10 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS06705 e52eb9d648da04075fe7311cc48aeb4f 351 SUPERFAMILY SSF56954 14 350 8.63E-28 T 29-03-2018 A616_RS06705 e52eb9d648da04075fe7311cc48aeb4f 351 Gene3D G3DSA:1.20.1600.10 153 240 4.2E-7 T 29-03-2018 A616_RS06705 e52eb9d648da04075fe7311cc48aeb4f 351 Gene3D G3DSA:1.20.1600.10 248 351 4.4E-14 T 29-03-2018 A616_RS06705 e52eb9d648da04075fe7311cc48aeb4f 351 Gene3D G3DSA:1.20.1600.10 16 150 2.6E-7 T 29-03-2018 A616_RS06705 e52eb9d648da04075fe7311cc48aeb4f 351 Pfam PF02321 Outer membrane efflux protein 248 350 1.7E-12 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A616_RS22605 4cd70cc1e10afa7e3482127395bf0260 338 PIRSF PIRSF011570 1 335 4.2E-154 T 29-03-2018 IPR010894 Stage V sporulation AD A616_RS22605 4cd70cc1e10afa7e3482127395bf0260 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 2.2E-150 T 29-03-2018 IPR010894 Stage V sporulation AD A616_RS22605 4cd70cc1e10afa7e3482127395bf0260 338 SUPERFAMILY SSF53901 57 309 1.11E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22605 4cd70cc1e10afa7e3482127395bf0260 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 2.3E-152 T 29-03-2018 IPR010894 Stage V sporulation AD A616_RS22605 4cd70cc1e10afa7e3482127395bf0260 338 Gene3D G3DSA:3.40.47.10 46 265 2.9E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22165 080091d5c8dc692413944fa8047440b1 197 SUPERFAMILY SSF101307 13 165 1.29E-45 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A616_RS22165 080091d5c8dc692413944fa8047440b1 197 Gene3D G3DSA:1.10.3760.10 1 180 3.0E-55 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A616_RS22165 080091d5c8dc692413944fa8047440b1 197 Pfam PF04608 Phosphatidylglycerophosphatase A 16 160 5.0E-16 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A616_RS22165 080091d5c8dc692413944fa8047440b1 197 PIRSF PIRSF019587 5 170 9.4E-63 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 Pfam PF01047 MarR family 29 84 6.4E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 1.9E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 1.9E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 1.9E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 Gene3D G3DSA:1.10.10.10 1 135 2.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 SMART SM00347 21 120 3.0E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS30565 4472b676b0e08424ecc85a7e538b3578 137 SUPERFAMILY SSF46785 3 135 7.43E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22930 e83ef9b8f630407db480ab39d67b27d6 332 Gene3D G3DSA:3.60.15.10 11 275 6.2E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22930 e83ef9b8f630407db480ab39d67b27d6 332 SMART SM00849 31 247 1.3E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22930 e83ef9b8f630407db480ab39d67b27d6 332 Pfam PF00753 Metallo-beta-lactamase superfamily 29 204 1.8E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22930 e83ef9b8f630407db480ab39d67b27d6 332 SUPERFAMILY SSF56281 14 331 8.52E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS14690 a99741a766a9f14a03c32fe4ad6ab82c 377 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 357 6.1E-46 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS14690 a99741a766a9f14a03c32fe4ad6ab82c 377 Pfam PF03845 Spore germination protein 11 321 9.5E-76 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26585 20be78a247583dc033ecdc8e15ffec23 331 Pfam PF04392 ABC transporter substrate binding protein 38 323 5.7E-31 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein A616_RS26585 20be78a247583dc033ecdc8e15ffec23 331 Gene3D G3DSA:3.40.50.2300 151 291 1.7E-9 T 29-03-2018 A616_RS26585 20be78a247583dc033ecdc8e15ffec23 331 Gene3D G3DSA:3.40.50.2300 32 150 6.2E-6 T 29-03-2018 A616_RS29605 a4ed8fabb72f2e05e93b39747978092f 121 Gene3D G3DSA:3.90.550.10 42 101 1.1E-6 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 SUPERFAMILY SSF50346 105 174 5.1E-20 T 29-03-2018 IPR011033 PRC-barrel-like A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 Pfam PF01782 RimM N-terminal domain 12 95 9.2E-21 T 29-03-2018 IPR002676 RimM protein GO:0006364 A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 9 174 24.11 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 Gene3D G3DSA:2.40.30.60 8 97 6.7E-21 T 29-03-2018 IPR002676 RimM protein GO:0006364 A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 Pfam PF05239 PRC-barrel domain 102 174 1.1E-11 T 29-03-2018 IPR027275 PRC-barrel domain A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 Gene3D G3DSA:2.30.30.240 101 169 7.0E-23 T 29-03-2018 A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 11 174 1.3E-52 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A616_RS20230 452f1dc65e25ccf33817033aa1ec406b 175 SUPERFAMILY SSF50447 10 97 6.83E-19 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 Gene3D G3DSA:3.30.190.20 149 227 4.5E-21 T 29-03-2018 A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 4.2E-56 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 SUPERFAMILY SSF56808 6 224 7.19E-85 T 29-03-2018 IPR023674 Ribosomal protein L1-like A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 PIRSF PIRSF002155 1 227 7.2E-82 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 3.4E-107 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 226 43.668 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A616_RS01325 aefcebfe53f6b99e5269d84aa3c139cc 227 Gene3D G3DSA:3.40.50.790 68 148 2.7E-37 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Pfam PF08279 HTH domain 17 55 1.8E-4 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Pfam PF00874 PRD domain 442 528 6.5E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Pfam PF00874 PRD domain 805 886 2.4E-5 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Gene3D G3DSA:3.40.50.510 526 674 2.2E-23 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Pfam PF03610 PTS system fructose IIA component 542 655 5.2E-7 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 SUPERFAMILY SSF53062 541 658 1.05E-14 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Gene3D G3DSA:3.40.50.300 64 305 9.4E-23 T 29-03-2018 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Pfam PF00158 Sigma-54 interaction domain 80 244 1.1E-46 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Gene3D G3DSA:1.10.1790.10 403 525 2.5E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Gene3D G3DSA:1.10.10.10 2 63 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 SMART SM00382 101 251 2.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 Gene3D G3DSA:1.10.1790.10 773 888 5.0E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 SUPERFAMILY SSF52540 96 321 2.35E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 SUPERFAMILY SSF63520 432 528 2.88E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 SUPERFAMILY SSF63520 804 887 1.83E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 SUPERFAMILY SSF46785 7 60 3.42E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31020 6b431678af21420e491c2bc53aaf4506 892 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 174 189 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS11540 0bf41a53bbeda6bfee8a2a6f1ff0c8e8 381 Gene3D G3DSA:2.120.10.30 21 153 4.3E-4 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS11540 0bf41a53bbeda6bfee8a2a6f1ff0c8e8 381 SUPERFAMILY SSF82171 52 184 2.75E-11 T 29-03-2018 A616_RS11540 0bf41a53bbeda6bfee8a2a6f1ff0c8e8 381 SUPERFAMILY SSF82171 240 360 2.75E-11 T 29-03-2018 A616_RS11540 0bf41a53bbeda6bfee8a2a6f1ff0c8e8 381 Gene3D G3DSA:2.130.10.150 154 372 1.5E-8 T 29-03-2018 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 Pfam PF00672 HAMP domain 182 230 1.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 SMART SM00304 182 234 6.8E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 458 1.3E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05675 5688995983b651d02b2a8752fae4280c 461 SMART SM00387 348 460 3.4E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05675 5688995983b651d02b2a8752fae4280c 461 SUPERFAMILY SSF158472 182 230 7.85E-8 T 29-03-2018 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 SUPERFAMILY SSF55874 305 458 2.49E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05675 5688995983b651d02b2a8752fae4280c 461 SMART SM00388 235 302 2.2E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 4.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 296 5.8E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 Gene3D G3DSA:3.30.565.10 305 460 2.5E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05675 5688995983b651d02b2a8752fae4280c 461 Gene3D G3DSA:1.10.287.130 225 297 1.6E-12 T 29-03-2018 A616_RS05675 5688995983b651d02b2a8752fae4280c 461 SUPERFAMILY SSF47384 218 298 6.08E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS11210 949c8eaa9b50bea16fe461e4e65ee80f 373 Pfam PF01926 50S ribosome-binding GTPase 164 237 1.2E-12 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS11210 949c8eaa9b50bea16fe461e4e65ee80f 373 SUPERFAMILY SSF52540 72 281 4.53E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11210 949c8eaa9b50bea16fe461e4e65ee80f 373 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 8 373 1.2E-139 T 29-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH A616_RS11210 949c8eaa9b50bea16fe461e4e65ee80f 373 Gene3D G3DSA:3.40.50.300 58 226 1.9E-31 T 29-03-2018 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 Gene3D G3DSA:3.40.50.300 340 575 3.2E-74 T 29-03-2018 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 SUPERFAMILY SSF52540 338 579 5.88E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 Pfam PF00005 ABC transporter 358 508 1.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 Gene3D G3DSA:1.20.1560.10 10 328 1.1E-70 T 29-03-2018 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 Pfam PF00664 ABC transporter transmembrane region 32 296 4.2E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 SUPERFAMILY SSF90123 18 327 2.75E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS23135 95ecfb14b52b029e1e360e769f1066dc 585 SMART SM00382 367 554 1.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12160 f35d1883735c8a631ce19df0ae60635b 228 SUPERFAMILY SSF48452 53 199 7.59E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12160 f35d1883735c8a631ce19df0ae60635b 228 Gene3D G3DSA:1.25.40.10 43 111 0.0012 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12160 f35d1883735c8a631ce19df0ae60635b 228 Gene3D G3DSA:1.25.40.10 154 227 5.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS12160 f35d1883735c8a631ce19df0ae60635b 228 Gene3D G3DSA:1.25.40.10 112 153 2.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS08955 29e38a0716e90f5af12a19fd0b4342fc 195 Pfam PF08819 Domain of unknown function (DUF1802) 13 187 1.3E-64 T 29-03-2018 IPR014923 Protein of unknown function DUF1802 A616_RS08955 29e38a0716e90f5af12a19fd0b4342fc 195 PIRSF PIRSF018957 5 194 4.0E-48 T 29-03-2018 IPR008307 Uncharacterised conserved protein UCP018957 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 Gene3D G3DSA:1.10.510.10 79 457 9.9E-59 T 29-03-2018 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 Gene3D G3DSA:3.30.200.20 1 78 8.6E-23 T 29-03-2018 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 SUPERFAMILY SSF56112 6 282 7.42E-86 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 SMART SM00740 501 570 0.025 T 29-03-2018 IPR005543 PASTA domain A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 SMART SM00740 430 500 1.3E-11 T 29-03-2018 IPR005543 PASTA domain A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 SMART SM00740 363 429 1.2E-10 T 29-03-2018 IPR005543 PASTA domain A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 SMART SM00220 10 270 1.2E-72 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 Pfam PF00069 Protein kinase domain 10 263 1.3E-55 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 Pfam PF03793 PASTA domain 368 429 2.1E-10 T 29-03-2018 IPR005543 PASTA domain A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 Pfam PF03793 PASTA domain 435 500 1.8E-11 T 29-03-2018 IPR005543 PASTA domain A616_RS20760 c444f5f73fa01a6bd7b873a8b35a1703 661 Pfam PF03793 PASTA domain 505 569 3.1E-5 T 29-03-2018 IPR005543 PASTA domain A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 Gene3D G3DSA:3.40.50.2000 835 998 1.5E-32 T 29-03-2018 A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 Pfam PF08241 Methyltransferase domain 42 123 7.4E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 Gene3D G3DSA:3.40.50.150 1 584 1.9E-32 T 29-03-2018 A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 Gene3D G3DSA:3.40.50.2000 631 834 1.3E-13 T 29-03-2018 A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 SUPERFAMILY SSF53335 15 179 1.96E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 Pfam PF13439 Glycosyltransferase Family 4 693 821 1.4E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 Pfam PF00534 Glycosyl transferases group 1 836 975 8.5E-30 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS29695 f9d690a075d78b36178f4102b6743c0d 1011 SUPERFAMILY SSF53756 617 1010 1.57E-65 T 29-03-2018 A616_RS05755 a9a8c69660eee1d31420a9dc63fedfc1 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 248 4.3E-42 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A616_RS01025 d6fa7e29613418351de6e9219a5d3f5c 299 Gene3D G3DSA:1.20.1070.10 1 295 4.0E-4 T 29-03-2018 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 243 259 2.1E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 57 72 2.1E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 109 133 2.1E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 135 155 2.1E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 158 173 2.1E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 78 98 2.1E-68 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 290 3.7E-163 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 Gene3D G3DSA:1.20.58.180 208 284 3.3E-36 T 29-03-2018 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 SUPERFAMILY SSF55681 3 282 1.99E-132 T 29-03-2018 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 Gene3D G3DSA:3.30.930.10 1 206 2.4E-84 T 29-03-2018 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 3 283 59.668 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11665 2568402b6b095e870d6e68a4e842ee0d 310 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 5 282 2.6E-151 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 Gene3D G3DSA:2.40.110.10 137 238 4.7E-36 T 29-03-2018 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 395 2.0E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 Gene3D G3DSA:1.10.540.10 1 135 1.7E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 SUPERFAMILY SSF56645 21 259 6.68E-86 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 SUPERFAMILY SSF47203 245 395 2.42E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 Gene3D G3DSA:1.20.140.10 239 396 5.5E-51 T 29-03-2018 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 354 373 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 134 3.2E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15385 86cd18bfd07484a81ea11671c48ba088 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 234 9.1E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS20210 41341618c4636037c301a149d8a421c9 297 Pfam PF01926 50S ribosome-binding GTPase 122 221 7.9E-16 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS20210 41341618c4636037c301a149d8a421c9 297 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 4.6E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS20210 41341618c4636037c301a149d8a421c9 297 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 4.6E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS20210 41341618c4636037c301a149d8a421c9 297 Gene3D G3DSA:3.40.50.300 12 179 1.0E-33 T 29-03-2018 A616_RS20210 41341618c4636037c301a149d8a421c9 297 Gene3D G3DSA:1.10.1580.10 180 272 2.7E-25 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain A616_RS20210 41341618c4636037c301a149d8a421c9 297 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 3.4E-116 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis A616_RS20210 41341618c4636037c301a149d8a421c9 297 PIRSF PIRSF006230 1 283 1.2E-105 T 29-03-2018 IPR016478 GTPase, MTG1 A616_RS20210 41341618c4636037c301a149d8a421c9 297 SUPERFAMILY SSF52540 9 263 1.8E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 Gene3D G3DSA:3.20.20.140 64 183 7.8E-8 T 29-03-2018 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 Pfam PF01979 Amidohydrolase family 55 337 4.3E-20 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 Gene3D G3DSA:2.30.40.10 248 348 8.5E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 SUPERFAMILY SSF51338 3 59 9.12E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 SUPERFAMILY SSF51338 308 340 9.12E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 Hamap MF_01518 Adenine deaminase [ade]. 4 565 32.304 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 Pfam PF13382 Adenine deaminase C-terminal domain 396 560 3.6E-54 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 SUPERFAMILY SSF51556 59 308 5.44E-18 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS31110 193a3bf07e84ab2da5f16f85a635a6a9 569 Gene3D G3DSA:2.30.40.10 1 63 6.3E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.50.980 2239 2397 1.6E-41 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF08242 Methyltransferase domain 839 940 3.9E-10 T 29-03-2018 IPR013217 Methyltransferase type 12 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.50.150 820 1044 9.2E-14 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF51735 1266 1473 2.86E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1269 1469 1.5E-25 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.47.10 30 294 2.5E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF00668 Condensation domain 1640 2070 7.2E-122 T 29-03-2018 IPR001242 Condensation domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF00668 Condensation domain 2668 2790 4.0E-9 T 29-03-2018 IPR001242 Condensation domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:1.10.1200.10 2597 2671 2.3E-16 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF53901 34 406 1.03E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF52777 1645 1807 5.67E-41 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:1.10.1200.10 1551 1622 1.7E-19 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF51735 1023 1246 8.97E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1581 1596 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2115 2510 2.3E-138 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 407 3.0E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF00550 Phosphopantetheine attachment site 2595 2656 3.8E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF00550 Phosphopantetheine attachment site 1560 1619 7.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SMART SM00825 Beta-ketoacyl synthase 40 462 2.5E-164 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.47.10 297 460 1.7E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF00501 AMP-binding enzyme 2094 2486 1.9E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF56801 2051 2605 7.85E-157 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF52777 2673 2881 1.22E-12 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF47336 2585 2658 2.09E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:2.30.38.10 2398 2476 8.6E-23 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF52777 1815 2080 3.78E-61 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF47336 1553 1622 5.1E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.30.559.10 1623 1829 9.7E-39 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SMART SM00823 Phosphopantetheine attachment site 1557 1626 2.0E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SMART SM00823 Phosphopantetheine attachment site 2593 2662 0.051 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF08659 KR domain 1269 1463 1.9E-46 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 520 1.5E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.50.720 1264 1515 3.1E-30 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.50.980 2085 2238 2.9E-47 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.30.300.30 2482 2596 1.8E-35 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF13193 AMP-binding enzyme C-terminal domain 2494 2566 1.2E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Gene3D G3DSA:3.40.50.720 1045 1184 2.6E-6 T 29-03-2018 A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2233 2244 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 SUPERFAMILY SSF53335 803 1014 4.7E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS18510 baf55b7f4bad91be0440d5505d43f6bc 2884 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 38 282 7.9E-69 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS04300 fcf03f61008aa2cce835c5e1dda441be 264 Pfam PF01501 Glycosyl transferase family 8 5 242 1.1E-47 T 29-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 A616_RS04300 fcf03f61008aa2cce835c5e1dda441be 264 SUPERFAMILY SSF53448 4 257 6.19E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS04300 fcf03f61008aa2cce835c5e1dda441be 264 Gene3D G3DSA:3.90.550.10 4 263 2.8E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 SUPERFAMILY SSF51735 119 257 1.89E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 SMART SM00829 10 321 4.3E-30 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 94 1.7E-10 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 Gene3D G3DSA:3.40.50.720 144 324 1.4E-27 T 29-03-2018 A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 Pfam PF13602 Zinc-binding dehydrogenase 189 321 1.3E-16 T 29-03-2018 A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 SUPERFAMILY SSF50129 1 147 1.83E-35 T 29-03-2018 IPR011032 GroES-like A616_RS23625 757fe00a939ca8d05fad0dfad24b5981 326 Gene3D G3DSA:3.90.180.10 1 143 3.4E-43 T 29-03-2018 A616_RS13930 c7b7fac807dd0385481fb456792fb852 231 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 226 4.2E-90 T 29-03-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 A616_RS13930 c7b7fac807dd0385481fb456792fb852 231 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 124 2.0E-20 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A616_RS13930 c7b7fac807dd0385481fb456792fb852 231 Gene3D G3DSA:3.40.50.10320 1 230 8.0E-57 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS13930 c7b7fac807dd0385481fb456792fb852 231 SUPERFAMILY SSF102588 4 228 3.27E-57 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24445 5fde29ea235ca7c026d9816432126da5 244 Gene3D G3DSA:3.90.470.20 30 145 9.0E-21 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS24445 5fde29ea235ca7c026d9816432126da5 244 Gene3D G3DSA:3.90.470.20 146 239 6.2E-13 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS24445 5fde29ea235ca7c026d9816432126da5 244 SUPERFAMILY SSF56214 30 127 1.83E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS24445 5fde29ea235ca7c026d9816432126da5 244 SUPERFAMILY SSF56214 136 239 1.57E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS24445 5fde29ea235ca7c026d9816432126da5 244 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 136 234 8.3E-15 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS18025 b171065d2da415682ee0cca456eda145 427 SUPERFAMILY SSF54106 2 47 4.05E-9 T 29-03-2018 IPR018392 LysM domain A616_RS18025 b171065d2da415682ee0cca456eda145 427 Pfam PF01476 LysM domain 4 47 2.2E-10 T 29-03-2018 IPR018392 LysM domain A616_RS18025 b171065d2da415682ee0cca456eda145 427 Pfam PF01476 LysM domain 53 96 2.8E-12 T 29-03-2018 IPR018392 LysM domain A616_RS18025 b171065d2da415682ee0cca456eda145 427 SMART SM00257 3 47 3.7E-10 T 29-03-2018 IPR018392 LysM domain A616_RS18025 b171065d2da415682ee0cca456eda145 427 SMART SM00257 52 96 1.5E-11 T 29-03-2018 IPR018392 LysM domain A616_RS18025 b171065d2da415682ee0cca456eda145 427 Pfam PF00704 Glycosyl hydrolases family 18 176 407 3.7E-22 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS18025 b171065d2da415682ee0cca456eda145 427 SUPERFAMILY SSF51445 125 321 7.85E-40 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS18025 b171065d2da415682ee0cca456eda145 427 SUPERFAMILY SSF51445 380 417 7.85E-40 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS18025 b171065d2da415682ee0cca456eda145 427 SUPERFAMILY SSF54106 52 96 6.8E-11 T 29-03-2018 IPR018392 LysM domain A616_RS18025 b171065d2da415682ee0cca456eda145 427 Gene3D G3DSA:3.10.350.10 2 49 2.9E-11 T 29-03-2018 A616_RS18025 b171065d2da415682ee0cca456eda145 427 Gene3D G3DSA:3.10.350.10 50 100 7.8E-14 T 29-03-2018 A616_RS18025 b171065d2da415682ee0cca456eda145 427 SMART SM00636 103 409 4.7E-18 T 29-03-2018 IPR011583 Chitinase II GO:0008061 A616_RS18025 b171065d2da415682ee0cca456eda145 427 Gene3D G3DSA:3.20.20.80 107 425 9.4E-42 T 29-03-2018 A616_RS06645 52deb3672f58659dfdbf2528dcfd381a 381 Gene3D G3DSA:3.20.20.70 22 380 3.5E-110 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS06645 52deb3672f58659dfdbf2528dcfd381a 381 Pfam PF01070 FMN-dependent dehydrogenase 32 379 1.6E-129 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 A616_RS06645 52deb3672f58659dfdbf2528dcfd381a 381 PIRSF PIRSF000138 3 381 1.3E-131 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 A616_RS06645 52deb3672f58659dfdbf2528dcfd381a 381 SUPERFAMILY SSF51395 23 378 3.36E-98 T 29-03-2018 A616_RS06645 52deb3672f58659dfdbf2528dcfd381a 381 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 276 282 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 A616_RS07410 a9f0ebd6b56461148ee581e46a215fc7 165 SUPERFAMILY SSF116726 85 160 2.88E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A616_RS07410 a9f0ebd6b56461148ee581e46a215fc7 165 Gene3D G3DSA:3.30.70.1450 74 164 1.8E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A616_RS07410 a9f0ebd6b56461148ee581e46a215fc7 165 Pfam PF02080 TrkA-C domain 91 160 2.7E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A616_RS07410 a9f0ebd6b56461148ee581e46a215fc7 165 PIRSF PIRSF005028 1 164 7.5E-59 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT A616_RS29730 df504e9872a69902fb8cf36124a81494 758 Pfam PF04932 O-Antigen ligase 194 409 2.1E-15 T 29-03-2018 IPR007016 O-antigen ligase-related A616_RS29730 df504e9872a69902fb8cf36124a81494 758 Gene3D G3DSA:1.25.40.10 168 541 0.008 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29730 df504e9872a69902fb8cf36124a81494 758 Gene3D G3DSA:1.25.40.10 542 615 3.0E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29730 df504e9872a69902fb8cf36124a81494 758 Gene3D G3DSA:1.25.40.10 620 758 1.6E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS29730 df504e9872a69902fb8cf36124a81494 758 SUPERFAMILY SSF81901 523 745 9.15E-11 T 29-03-2018 A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 Gene3D G3DSA:3.90.550.10 1 239 2.0E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 SUPERFAMILY SSF53448 3 252 5.01E-65 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 283 315 0.0018 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 327 8.6E-112 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 Pfam PF00483 Nucleotidyl transferase 5 219 6.3E-24 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 SUPERFAMILY SSF51161 248 334 9.7E-18 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS07840 efe7f80d7dacfbe5d8dc05aff5de7dba 340 Gene3D G3DSA:2.160.10.10 240 335 2.0E-21 T 29-03-2018 A616_RS13710 5e8de7431ce86ea9c7b40f05484c5da9 242 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 24 240 1.0E-40 T 29-03-2018 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SUPERFAMILY SSF49265 180 277 2.2E-15 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.10 349 429 1.7E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SMART SM00635 609 690 3.6E-11 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SMART SM00635 438 516 4.3E-13 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SMART SM00635 521 604 11.0 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SMART SM00635 696 776 0.14 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SMART SM00060 182 256 7.7E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SUPERFAMILY SSF49373 731 777 2.04E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.10 181 288 3.2E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.1080 694 778 3.1E-16 T 29-03-2018 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.1080 608 693 2.1E-17 T 29-03-2018 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.1080 523 607 5.7E-5 T 29-03-2018 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SUPERFAMILY SSF49785 46 177 3.69E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SUPERFAMILY SSF49373 609 691 1.26E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Pfam PF16403 Domain of unknown function (DUF5011) 355 424 1.7E-16 T 29-03-2018 IPR032179 Domain of unknown function DUF5011 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.10 289 344 6.5E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Pfam PF00041 Fibronectin type III domain 185 259 1.2E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Pfam PF00754 F5/8 type C domain 59 170 4.8E-16 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Pfam PF02368 Bacterial Ig-like domain (group 2) 733 764 2.0E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Pfam PF02368 Bacterial Ig-like domain (group 2) 610 678 6.1E-7 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Pfam PF02368 Bacterial Ig-like domain (group 2) 450 517 1.6E-14 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.120.260 39 180 2.7E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 Gene3D G3DSA:2.60.40.1080 434 522 9.9E-24 T 29-03-2018 A616_RS28285 06517d8bf6dfda19898003d2ef31b3b1 778 SUPERFAMILY SSF49373 436 519 1.06E-17 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS09565 26bde0aa439e1ab4c0345ac51da958e1 217 SUPERFAMILY SSF51735 3 134 6.3E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09565 26bde0aa439e1ab4c0345ac51da958e1 217 SUPERFAMILY SSF116726 131 215 2.35E-23 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A616_RS09565 26bde0aa439e1ab4c0345ac51da958e1 217 Pfam PF02080 TrkA-C domain 150 216 1.1E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A616_RS09565 26bde0aa439e1ab4c0345ac51da958e1 217 Gene3D G3DSA:3.30.70.1450 136 217 6.1E-26 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A616_RS09565 26bde0aa439e1ab4c0345ac51da958e1 217 Gene3D G3DSA:3.40.50.720 3 135 1.1E-22 T 29-03-2018 A616_RS09565 26bde0aa439e1ab4c0345ac51da958e1 217 Pfam PF02254 TrkA-N domain 5 120 6.3E-31 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 Gene3D G3DSA:3.10.180.10 164 363 2.9E-72 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 10 118 1.5E-11 T 29-03-2018 A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 11 363 1.9E-139 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 PIRSF PIRSF009283 1 363 1.5E-137 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 Gene3D G3DSA:3.10.180.10 2 163 4.7E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 168 317 4.4E-19 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS23935 478a15bbe9007c6cae3a4d94e652ecf7 363 SUPERFAMILY SSF54593 5 350 1.48E-94 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 SUPERFAMILY SSF46894 134 224 2.1E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 SMART SM01043 239 369 3.7E-4 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 SMART SM00448 2 112 1.4E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 Pfam PF00072 Response regulator receiver domain 4 110 3.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 SUPERFAMILY SSF52172 3 132 5.98E-28 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 Gene3D G3DSA:1.10.10.10 130 226 1.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 SMART SM00862 148 224 0.003 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 Gene3D G3DSA:3.40.50.2300 1 129 2.0E-27 T 29-03-2018 A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 Pfam PF03704 Bacterial transcriptional activator domain 257 363 5.4E-8 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain A616_RS24240 4b9c19bfc7e3ea53a68ebcb1cdfd2886 371 SUPERFAMILY SSF48452 255 368 2.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13020 3246b0bf6e0eca3ef8f6c5b869f45f3f 562 Gene3D G3DSA:2.60.40.1640 269 440 7.1E-9 T 29-03-2018 A616_RS13020 3246b0bf6e0eca3ef8f6c5b869f45f3f 562 Gene3D G3DSA:2.60.40.1630 117 264 4.9E-20 T 29-03-2018 A616_RS13020 3246b0bf6e0eca3ef8f6c5b869f45f3f 562 Pfam PF13786 Domain of unknown function (DUF4179) 89 173 3.1E-18 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 Gene3D G3DSA:3.40.50.620 2 223 1.4E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 Gene3D G3DSA:3.10.290.10 325 420 1.3E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 SUPERFAMILY SSF52374 2 323 7.13E-108 T 29-03-2018 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 Pfam PF00579 tRNA synthetases class I (W and Y) 27 323 9.4E-85 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 1.3E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 1.3E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 1.3E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 1.3E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 Gene3D G3DSA:1.10.240.10 224 324 8.6E-37 T 29-03-2018 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 SUPERFAMILY SSF55174 321 417 2.36E-21 T 29-03-2018 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 43.89 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 Pfam PF01479 S4 domain 355 396 3.3E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS15625 3ab6aba5358ccc509708251557ff1ec7 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 417 7.4E-129 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A616_RS03265 2a0f4b1ab6245562cbe89c36248587e3 520 Gene3D G3DSA:3.90.76.10 56 198 7.9E-41 T 29-03-2018 A616_RS03265 2a0f4b1ab6245562cbe89c36248587e3 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 443 1.6E-90 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS03265 2a0f4b1ab6245562cbe89c36248587e3 520 SUPERFAMILY SSF53850 41 512 8.51E-133 T 29-03-2018 A616_RS03265 2a0f4b1ab6245562cbe89c36248587e3 520 Gene3D G3DSA:3.10.105.10 293 492 7.4E-51 T 29-03-2018 A616_RS03265 2a0f4b1ab6245562cbe89c36248587e3 520 PIRSF PIRSF002741 2 519 3.7E-119 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS03265 2a0f4b1ab6245562cbe89c36248587e3 520 Gene3D G3DSA:3.40.190.10 199 292 1.3E-27 T 29-03-2018 A616_RS01950 97bc0b91c38e5e65fc452dd73085eb6f 213 Gene3D G3DSA:3.40.109.10 3 213 3.3E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS01950 97bc0b91c38e5e65fc452dd73085eb6f 213 SUPERFAMILY SSF55469 1 209 1.57E-47 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS01950 97bc0b91c38e5e65fc452dd73085eb6f 213 Pfam PF00881 Nitroreductase family 9 184 2.0E-23 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00412 Epoxide hydrolase signature 50 68 5.0E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00412 Epoxide hydrolase signature 114 127 5.0E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00412 Epoxide hydrolase signature 287 309 5.0E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00412 Epoxide hydrolase signature 253 269 5.0E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00412 Epoxide hydrolase signature 128 141 5.0E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 SUPERFAMILY SSF53474 18 310 3.59E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 Pfam PF00561 alpha/beta hydrolase fold 45 297 2.1E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 Gene3D G3DSA:3.40.50.1820 14 313 8.2E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 7.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 69 84 7.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS17850 673d654afab09478c0dc7e63f11d2863 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 128 141 7.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 249 9.0E-69 T 29-03-2018 A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 Gene3D G3DSA:3.40.50.720 39 252 7.5E-60 T 29-03-2018 A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 Gene3D G3DSA:3.40.50.720 1 38 3.7E-9 T 29-03-2018 A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 SUPERFAMILY SSF51735 5 250 6.27E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 4.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS05820 e422a0fc14f9d411a6206bd0538871de 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS24055 18de411fa44adf73dc8f7458ddd8aa7e 157 Gene3D G3DSA:3.40.630.30 7 146 7.5E-21 T 29-03-2018 A616_RS24055 18de411fa44adf73dc8f7458ddd8aa7e 157 Pfam PF00583 Acetyltransferase (GNAT) family 42 122 2.1E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS24055 18de411fa44adf73dc8f7458ddd8aa7e 157 SUPERFAMILY SSF55729 9 153 9.09E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 SUPERFAMILY SSF51905 7 222 4.66E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 SUPERFAMILY SSF51905 331 390 4.66E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 30 4.6E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 323 329 4.6E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 7 19 4.6E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 48 4.6E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 Pfam PF01266 FAD dependent oxidoreductase 9 370 9.4E-69 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 Gene3D G3DSA:3.30.9.10 100 164 5.2E-12 T 29-03-2018 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 SUPERFAMILY SSF54373 272 330 1.29E-10 T 29-03-2018 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 Gene3D G3DSA:3.40.50.720 1 99 5.4E-8 T 29-03-2018 A616_RS25150 0ee0392dfe48823ecd47115eb26dc880 397 Gene3D G3DSA:3.30.9.10 165 330 3.2E-28 T 29-03-2018 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 Gene3D G3DSA:2.40.50.140 13 107 1.6E-13 T 29-03-2018 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 2.1E-19 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 2.1E-19 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 PRINTS PR01042 Aspartyl-tRNA synthetase signature 356 372 2.1E-19 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 PRINTS PR01042 Aspartyl-tRNA synthetase signature 396 410 2.1E-19 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 10 441 36.76 T 29-03-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 Gene3D G3DSA:3.30.930.10 111 428 7.0E-75 T 29-03-2018 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 24 441 6.1E-116 T 29-03-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 SUPERFAMILY SSF55681 121 435 4.07E-78 T 29-03-2018 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 SUPERFAMILY SSF50249 19 97 6.67E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 434 2.6E-73 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS28860 da17a4f59d54275309a0134d4d795d42 441 Pfam PF01336 OB-fold nucleic acid binding domain 27 95 3.9E-11 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 Gene3D G3DSA:3.40.630.10 2 250 1.9E-44 T 29-03-2018 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 Gene3D G3DSA:3.40.630.10 252 394 3.1E-25 T 29-03-2018 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 381 8.0E-117 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 Pfam PF01546 Peptidase family M20/M25/M40 79 390 8.5E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 PIRSF PIRSF005962 7 393 9.9E-136 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 SUPERFAMILY SSF55031 187 304 2.75E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 Pfam PF07687 Peptidase dimerisation domain 191 274 2.1E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 SUPERFAMILY SSF53187 304 392 5.69E-84 T 29-03-2018 A616_RS07665 42ecd5de94afc5134449adfdf1ce589b 394 SUPERFAMILY SSF53187 9 203 5.69E-84 T 29-03-2018 A616_RS01585 8b2a96723eb83f413214d00cd4afab42 214 Gene3D G3DSA:3.40.190.10 1 151 1.4E-5 T 29-03-2018 A616_RS32300 fd75a5f93aba7414593e7064f69eef03 81 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 14 80 5.3E-32 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A616_RS32300 fd75a5f93aba7414593e7064f69eef03 81 SMART SM01234 9 76 2.5E-46 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A616_RS32300 fd75a5f93aba7414593e7064f69eef03 81 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 9 77 24.86 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A616_RS32300 fd75a5f93aba7414593e7064f69eef03 81 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 24 76 1.0E-19 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A616_RS32300 fd75a5f93aba7414593e7064f69eef03 81 Pfam PF01809 Haemolytic domain 11 76 3.0E-31 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 Pfam PF04715 Anthranilate synthase component I, N terminal region 28 167 1.3E-36 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 489 1.8E-175 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 PRINTS PR00095 Anthranilate synthase component I signature 438 452 1.5E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 PRINTS PR00095 Anthranilate synthase component I signature 343 356 1.5E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 PRINTS PR00095 Anthranilate synthase component I signature 423 437 1.5E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 PRINTS PR00095 Anthranilate synthase component I signature 329 342 1.5E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 Pfam PF00425 chorismate binding enzyme 228 481 3.2E-98 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 SUPERFAMILY SSF56322 16 492 7.2E-160 T 29-03-2018 IPR005801 ADC synthase GO:0009058 A616_RS13805 5d347ef0fcfbe27fdbfdcec8bec7334a 504 Gene3D G3DSA:3.60.120.10 15 491 9.3E-168 T 29-03-2018 IPR005801 ADC synthase GO:0009058 A616_RS29290 77b7af7540727d319290ca28fcd8af13 400 SUPERFAMILY SSF51261 228 399 2.2E-55 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS29290 77b7af7540727d319290ca28fcd8af13 400 Pfam PF01551 Peptidase family M23 299 395 8.1E-33 T 29-03-2018 IPR016047 Peptidase M23 A616_RS29290 77b7af7540727d319290ca28fcd8af13 400 Gene3D G3DSA:2.70.70.10 175 400 2.7E-47 T 29-03-2018 A616_RS29290 77b7af7540727d319290ca28fcd8af13 400 Gene3D G3DSA:1.10.287.620 28 144 6.6E-7 T 29-03-2018 A616_RS29290 77b7af7540727d319290ca28fcd8af13 400 SUPERFAMILY SSF57997 33 123 1.93E-7 T 29-03-2018 A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 SUPERFAMILY SSF56281 532 795 6.16E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 Pfam PF13567 Domain of unknown function (DUF4131) 31 192 3.3E-24 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 SMART SM00849 542 751 6.2E-6 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 258 430 7.8E-31 T 29-03-2018 IPR004477 ComEC/Rec2-related protein A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 Pfam PF00753 Metallo-beta-lactamase superfamily 539 750 1.3E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 Pfam PF03772 Competence protein 236 500 8.2E-55 T 29-03-2018 IPR004477 ComEC/Rec2-related protein A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 159 780 2.2E-96 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 A616_RS11265 27dfb5f7104e164f8f1885a7d3a768d4 800 Gene3D G3DSA:3.60.15.10 523 785 1.1E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS04315 830d9a559c5c4e676db4237149cbbac6 144 Gene3D G3DSA:1.25.40.70 4 75 1.7E-4 T 29-03-2018 A616_RS04315 830d9a559c5c4e676db4237149cbbac6 144 Pfam PF13646 HEAT repeats 16 74 1.5E-6 T 29-03-2018 A616_RS27515 4e60773e3bb2b395bd17052dd05179ac 442 SUPERFAMILY SSF56801 26 405 2.22E-59 T 29-03-2018 A616_RS27515 4e60773e3bb2b395bd17052dd05179ac 442 Pfam PF00501 AMP-binding enzyme 75 333 7.4E-13 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS27515 4e60773e3bb2b395bd17052dd05179ac 442 Gene3D G3DSA:3.40.50.980 76 247 5.2E-16 T 29-03-2018 A616_RS27515 4e60773e3bb2b395bd17052dd05179ac 442 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 435 9.0E-25 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal A616_RS27515 4e60773e3bb2b395bd17052dd05179ac 442 Gene3D G3DSA:3.30.300.30 325 438 1.6E-8 T 29-03-2018 A616_RS27515 4e60773e3bb2b395bd17052dd05179ac 442 PIRSF PIRSF006444 1 437 1.4E-198 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 357 49.999 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 Gene3D G3DSA:3.40.718.10 1 361 3.0E-126 T 29-03-2018 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 SMART SM01329 6 353 4.6E-198 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 SUPERFAMILY SSF53659 4 357 1.48E-121 T 29-03-2018 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 351 5.0E-155 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A616_RS09495 6a7c5acc8e549b65d519cf05e0ab9854 364 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 353 6.1E-135 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A616_RS11555 1feac1c96bc559bc0e8c4bc19385a085 414 SUPERFAMILY SSF56801 90 407 4.06E-57 T 29-03-2018 A616_RS11555 1feac1c96bc559bc0e8c4bc19385a085 414 Pfam PF00501 AMP-binding enzyme 86 278 4.7E-17 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS11555 1feac1c96bc559bc0e8c4bc19385a085 414 Gene3D G3DSA:3.30.300.30 313 411 3.5E-20 T 29-03-2018 A616_RS11555 1feac1c96bc559bc0e8c4bc19385a085 414 Gene3D G3DSA:3.40.50.980 90 258 2.3E-18 T 29-03-2018 A616_RS11555 1feac1c96bc559bc0e8c4bc19385a085 414 Pfam PF13193 AMP-binding enzyme C-terminal domain 328 401 2.6E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS11555 1feac1c96bc559bc0e8c4bc19385a085 414 ProSitePatterns PS00455 Putative AMP-binding domain signature. 106 117 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 Pfam PF11563 Protoglobin 37 190 1.0E-42 T 29-03-2018 A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 SMART SM00283 206 438 4.9E-28 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 SUPERFAMILY SSF46458 37 182 7.75E-40 T 29-03-2018 IPR009050 Globin-like A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 Gene3D G3DSA:1.10.287.950 227 438 2.2E-43 T 29-03-2018 A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 SUPERFAMILY SSF58104 205 437 2.09E-55 T 29-03-2018 A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 SUPERFAMILY SSF58104 141 156 2.09E-55 T 29-03-2018 A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 Gene3D G3DSA:1.10.490.10 27 191 1.2E-33 T 29-03-2018 A616_RS26605 25237fde28f5c3e45dbdbc38561b4444 438 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 271 426 7.8E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS24850 f6fa374405eed474f21537f813d6154e 188 Hamap MF_01575 UPF0398 protein . 2 178 33.645 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 A616_RS24850 f6fa374405eed474f21537f813d6154e 188 Gene3D G3DSA:3.40.50.450 1 181 5.5E-33 T 29-03-2018 A616_RS24850 f6fa374405eed474f21537f813d6154e 188 SUPERFAMILY SSF102405 2 178 1.1E-59 T 29-03-2018 A616_RS24850 f6fa374405eed474f21537f813d6154e 188 Pfam PF06908 Protein of unknown function (DUF1273) 5 172 4.6E-68 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 A616_RS24850 f6fa374405eed474f21537f813d6154e 188 PIRSF PIRSF021290 2 180 2.4E-65 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 Pfam PF01614 Bacterial transcriptional regulator 132 255 5.0E-29 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 SUPERFAMILY SSF46785 15 88 1.78E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 Pfam PF09339 IclR helix-turn-helix domain 15 63 1.2E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 SMART SM00346 13 104 1.4E-22 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 SUPERFAMILY SSF55781 72 260 3.99E-47 T 29-03-2018 IPR029016 GAF domain-like A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 Gene3D G3DSA:3.30.450.40 101 264 2.9E-44 T 29-03-2018 IPR029016 GAF domain-like A616_RS14635 0cdc4ad0f5cb8ca1525653fad3c8ece4 267 Gene3D G3DSA:1.10.10.10 7 100 1.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02725 8eb6dc6e2a57c8560735d59cd6543edf 550 Gene3D G3DSA:3.10.105.10 322 519 2.8E-62 T 29-03-2018 A616_RS02725 8eb6dc6e2a57c8560735d59cd6543edf 550 Gene3D G3DSA:3.40.190.10 184 321 1.1E-42 T 29-03-2018 A616_RS02725 8eb6dc6e2a57c8560735d59cd6543edf 550 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 92 469 8.2E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS02725 8eb6dc6e2a57c8560735d59cd6543edf 550 Gene3D G3DSA:3.90.76.10 74 183 3.4E-31 T 29-03-2018 A616_RS02725 8eb6dc6e2a57c8560735d59cd6543edf 550 SUPERFAMILY SSF53850 45 542 5.97E-141 T 29-03-2018 A616_RS02725 8eb6dc6e2a57c8560735d59cd6543edf 550 PIRSF PIRSF002741 2 550 1.6E-135 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 Gene3D G3DSA:1.10.601.10 5 104 1.3E-33 T 29-03-2018 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 SUPERFAMILY SSF88659 170 250 1.25E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 21 249 1.2E-111 T 29-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 SUPERFAMILY SSF88659 108 184 1.44E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 Pfam PF04539 Sigma-70 region 3 114 179 9.8E-14 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 Gene3D G3DSA:1.10.10.10 105 157 9.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 Gene3D G3DSA:1.10.10.10 188 245 1.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 249 1.3E-86 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PIRSF PIRSF000770 101 251 1.3E-17 T 29-03-2018 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PIRSF PIRSF000770 8 103 6.6E-20 T 29-03-2018 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 Pfam PF04542 Sigma-70 region 2 36 103 7.5E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 248 5.3E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PRINTS PR00046 Major sigma-70 factor signature 202 214 3.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PRINTS PR00046 Major sigma-70 factor signature 219 234 3.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PRINTS PR00046 Major sigma-70 factor signature 60 73 3.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PRINTS PR00046 Major sigma-70 factor signature 234 245 3.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 PRINTS PR00046 Major sigma-70 factor signature 84 92 3.7E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 Pfam PF04545 Sigma-70, region 4 198 247 3.1E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13410 b85cf875a698eab7780ff2ed446f510d 251 SUPERFAMILY SSF88946 10 104 6.93E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 581 4.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 SUPERFAMILY SSF47384 343 425 7.85E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 SUPERFAMILY SSF55874 414 579 3.14E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 Gene3D G3DSA:1.10.287.130 347 418 4.9E-11 T 29-03-2018 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 4.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 4.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 4.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 4.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 SMART SM00387 471 583 9.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 358 418 7.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 Gene3D G3DSA:3.30.565.10 419 587 5.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25820 1fac081aa6dceff031feb43ac22a7fd2 587 SMART SM00388 357 425 2.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 Gene3D G3DSA:1.10.10.10 130 236 8.6E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 SMART SM00448 7 118 3.8E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 SMART SM00862 155 231 3.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 SUPERFAMILY SSF52172 5 182 3.77E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 2.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 Gene3D G3DSA:3.40.50.2300 1 129 8.4E-31 T 29-03-2018 A616_RS17965 356ed972ca9b76d35b5dbbd93a302b84 237 Pfam PF00072 Response regulator receiver domain 9 117 8.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31585 5c2257e77be7efece4f396df915c5267 343 SUPERFAMILY SSF52540 6 241 2.54E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31585 5c2257e77be7efece4f396df915c5267 343 Pfam PF08402 TOBE domain 252 332 1.7E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS31585 5c2257e77be7efece4f396df915c5267 343 Gene3D G3DSA:3.40.50.300 3 274 3.1E-79 T 29-03-2018 A616_RS31585 5c2257e77be7efece4f396df915c5267 343 Pfam PF00005 ABC transporter 21 162 1.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS31585 5c2257e77be7efece4f396df915c5267 343 SUPERFAMILY SSF50331 245 335 7.82E-10 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS31585 5c2257e77be7efece4f396df915c5267 343 SMART SM00382 30 212 2.0E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31585 5c2257e77be7efece4f396df915c5267 343 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 SUPERFAMILY SSF47384 149 213 1.24E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 261 363 2.1E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 Gene3D G3DSA:3.30.565.10 218 371 1.7E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 SUPERFAMILY SSF55874 211 363 4.32E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 SMART SM00388 154 216 8.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 SMART SM00387 259 367 1.2E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 Gene3D G3DSA:1.10.287.130 142 212 1.1E-9 T 29-03-2018 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 313 5.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 346 5.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 327 5.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 155 214 1.0E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS27990 789d060f45bc4fc5c51b1e96763989c4 380 Pfam PF09385 Histidine kinase N terminal 5 131 1.3E-46 T 29-03-2018 IPR018984 Histidine kinase, N-terminal A616_RS27720 6f8a4ff014b0bb337056df5876f54400 425 Pfam PF05139 Erythromycin esterase 75 416 1.5E-69 T 29-03-2018 IPR007815 Erythromycin esterase GO:0046677 A616_RS27720 6f8a4ff014b0bb337056df5876f54400 425 Gene3D G3DSA:3.40.1660.10 172 423 1.3E-24 T 29-03-2018 A616_RS27720 6f8a4ff014b0bb337056df5876f54400 425 Gene3D G3DSA:3.30.1870.10 77 152 2.0E-19 T 29-03-2018 A616_RS27720 6f8a4ff014b0bb337056df5876f54400 425 SUPERFAMILY SSF159501 23 421 2.35E-89 T 29-03-2018 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 Gene3D G3DSA:3.30.420.40 1 248 2.9E-71 T 29-03-2018 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 PIRSF PIRSF000538 2 505 7.4E-136 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 SUPERFAMILY SSF53067 3 255 2.71E-73 T 29-03-2018 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 250 6.0E-65 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 SUPERFAMILY SSF53067 255 500 1.23E-60 T 29-03-2018 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 454 4.3E-45 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A616_RS23710 2003243f2ac43fff453ad77575ed8ad6 506 Gene3D G3DSA:3.30.420.40 249 505 7.0E-55 T 29-03-2018 A616_RS01865 179826e733f572b10654f1025f068a9c 336 Gene3D G3DSA:3.40.50.1820 13 328 5.3E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01865 179826e733f572b10654f1025f068a9c 336 SUPERFAMILY SSF53474 1 313 1.54E-78 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01865 179826e733f572b10654f1025f068a9c 336 PIRSF PIRSF000443 1 336 3.3E-82 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 A616_RS01865 179826e733f572b10654f1025f068a9c 336 Pfam PF00561 alpha/beta hydrolase fold 40 313 2.5E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS16375 d3947e61d887098579eae3af317b2746 292 SUPERFAMILY SSF88723 4 174 3.19E-43 T 29-03-2018 IPR029060 PIN domain-like A616_RS16375 d3947e61d887098579eae3af317b2746 292 Gene3D G3DSA:3.40.50.1010 5 191 8.7E-55 T 29-03-2018 IPR029060 PIN domain-like A616_RS16375 d3947e61d887098579eae3af317b2746 292 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 178 267 6.6E-32 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A616_RS16375 d3947e61d887098579eae3af317b2746 292 SUPERFAMILY SSF47807 178 286 1.5E-30 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A616_RS16375 d3947e61d887098579eae3af317b2746 292 SMART SM00279 180 215 1.2E-11 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A616_RS16375 d3947e61d887098579eae3af317b2746 292 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 170 1.7E-45 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A616_RS16375 d3947e61d887098579eae3af317b2746 292 Gene3D G3DSA:1.10.150.20 192 269 5.5E-30 T 29-03-2018 A616_RS16375 d3947e61d887098579eae3af317b2746 292 SMART SM00475 5 268 1.5E-97 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A616_RS05275 36189de59e7cdf7b3310b211700d7c39 306 Pfam PF01619 Proline dehydrogenase 45 299 1.8E-33 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 A616_RS05275 36189de59e7cdf7b3310b211700d7c39 306 Gene3D G3DSA:3.20.20.220 10 305 1.1E-67 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like A616_RS05275 36189de59e7cdf7b3310b211700d7c39 306 SUPERFAMILY SSF51730 37 302 2.43E-73 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like A616_RS05275 36189de59e7cdf7b3310b211700d7c39 306 PIRSF PIRSF000196 1 306 5.1E-128 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 64 2.3E-31 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 65 26.996 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 SUPERFAMILY SSF143800 1 64 4.32E-26 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 Pfam PF01197 Ribosomal protein L31 1 64 1.7E-31 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.6E-23 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 PRINTS PR01249 Ribosomal protein L31 signature 45 63 5.6E-23 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS30065 02882dd715dec13f990e1dca07218e93 65 PRINTS PR01249 Ribosomal protein L31 signature 30 45 5.6E-23 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS18325 2c58ab4c1e8c4b3378dac8297eb3503a 371 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 3 363 8.9E-144 T 29-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 A616_RS18325 2c58ab4c1e8c4b3378dac8297eb3503a 371 SUPERFAMILY SSF53383 9 361 1.96E-36 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS18325 2c58ab4c1e8c4b3378dac8297eb3503a 371 Pfam PF03841 L-seryl-tRNA selenium transferase 12 264 1.4E-16 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 A616_RS18325 2c58ab4c1e8c4b3378dac8297eb3503a 371 Gene3D G3DSA:3.40.640.10 22 274 1.2E-26 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS21420 c4118e30acbcbb7fc84d0b7d3b04e4c9 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 219 6.5E-49 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS21420 c4118e30acbcbb7fc84d0b7d3b04e4c9 255 SUPERFAMILY SSF52096 1 253 8.45E-71 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS21420 c4118e30acbcbb7fc84d0b7d3b04e4c9 255 Gene3D G3DSA:3.90.226.10 1 255 2.8E-69 T 29-03-2018 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 SUPERFAMILY SSF54534 83 156 1.31E-20 T 29-03-2018 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 31.013 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 Gene3D G3DSA:1.10.287.180 5 77 2.9E-31 T 29-03-2018 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 PIRSF PIRSF006092 1 158 6.0E-50 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 1.0E-53 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 Pfam PF03449 Transcription elongation factor, N-terminal 6 76 1.1E-30 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 1.2E-25 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 Gene3D G3DSA:3.10.50.30 78 158 3.3E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A616_RS01170 a3b5dc9791f3a441bccda11f11fd46b9 158 SUPERFAMILY SSF46557 4 77 4.19E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A616_RS15165 0633c6516d1b60b26ac12a191aa05b34 325 Pfam PF04960 Glutaminase 30 325 1.2E-107 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS15165 0633c6516d1b60b26ac12a191aa05b34 325 TIGRFAM TIGR03814 Gln_ase: glutaminase A 16 325 7.1E-118 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS15165 0633c6516d1b60b26ac12a191aa05b34 325 Gene3D G3DSA:3.40.710.10 7 325 1.1E-117 T 29-03-2018 A616_RS15165 0633c6516d1b60b26ac12a191aa05b34 325 Hamap MF_00313 Glutaminase [glsA]. 12 325 43.95 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS15165 0633c6516d1b60b26ac12a191aa05b34 325 SUPERFAMILY SSF56601 10 325 5.5E-118 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS15575 3d95e0dab058bedd28654abbc0f3d2dd 552 Pfam PF00743 Flavin-binding monooxygenase-like 19 221 2.1E-15 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 A616_RS15575 3d95e0dab058bedd28654abbc0f3d2dd 552 SUPERFAMILY SSF51905 156 388 6.39E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15575 3d95e0dab058bedd28654abbc0f3d2dd 552 SUPERFAMILY SSF51905 319 541 4.66E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15575 3d95e0dab058bedd28654abbc0f3d2dd 552 SUPERFAMILY SSF51905 14 220 7.12E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15575 3d95e0dab058bedd28654abbc0f3d2dd 552 Gene3D G3DSA:3.50.50.60 1 172 9.9E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15575 3d95e0dab058bedd28654abbc0f3d2dd 552 Gene3D G3DSA:3.50.50.60 173 543 8.0E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 Pfam PF01546 Peptidase family M20/M25/M40 67 369 1.5E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 Pfam PF07687 Peptidase dimerisation domain 181 269 6.6E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 SUPERFAMILY SSF55031 178 283 7.72E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 Gene3D G3DSA:3.40.630.10 3 272 2.1E-50 T 29-03-2018 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 SUPERFAMILY SSF53187 290 369 3.55E-67 T 29-03-2018 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 SUPERFAMILY SSF53187 6 189 3.55E-67 T 29-03-2018 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 PIRSF PIRSF005962 1 376 1.7E-105 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 373 63.237 T 29-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 A616_RS21635 694e8c4ee6867661e3c55765a3e4caf4 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 362 9.6E-84 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 PRINTS PR00412 Epoxide hydrolase signature 206 222 8.7E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 PRINTS PR00412 Epoxide hydrolase signature 28 46 8.7E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 PRINTS PR00412 Epoxide hydrolase signature 237 259 8.7E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 5.9E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 5.9E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 5.9E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 Gene3D G3DSA:3.40.50.1820 5 263 1.2E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 Pfam PF12697 Alpha/beta hydrolase family 24 255 3.2E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS10370 71d94d42c45a47b348d9727e4ac55251 263 SUPERFAMILY SSF53474 5 262 1.22E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS29280 b564c7b81b3e4a9adc41b4a2a15bda6a 453 SUPERFAMILY SSF50156 341 431 1.65E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS29280 b564c7b81b3e4a9adc41b4a2a15bda6a 453 SMART SM00228 334 399 8.0E-4 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS29280 b564c7b81b3e4a9adc41b4a2a15bda6a 453 Gene3D G3DSA:2.30.42.10 338 406 5.5E-10 T 29-03-2018 A616_RS23575 7049a87cc65def529067b443d893a9bd 418 SUPERFAMILY SSF103473 21 413 7.32E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS23575 7049a87cc65def529067b443d893a9bd 418 Gene3D G3DSA:1.20.1250.20 213 411 3.4E-11 T 29-03-2018 A616_RS23575 7049a87cc65def529067b443d893a9bd 418 Gene3D G3DSA:1.20.1250.20 12 212 2.8E-23 T 29-03-2018 A616_RS23575 7049a87cc65def529067b443d893a9bd 418 Pfam PF07690 Major Facilitator Superfamily 26 363 2.4E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 SUPERFAMILY SSF159664 247 374 1.31E-38 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 Pfam PF11761 Cobalamin biosynthesis central region 157 251 5.7E-13 T 29-03-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 Pfam PF11760 Cobalamin synthesis G N-terminal 72 151 1.7E-34 T 29-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 Gene3D G3DSA:3.30.420.180 244 373 8.4E-38 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 Pfam PF01890 Cobalamin synthesis G C-terminus 254 370 2.9E-34 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 SUPERFAMILY SSF159672 19 204 1.57E-58 T 29-03-2018 A616_RS07360 d8c84848515430dc95825c94b61509ec 381 SUPERFAMILY SSF159672 233 261 1.57E-58 T 29-03-2018 A616_RS23950 e697310718df93e3627837138638db53 227 SUPERFAMILY SSF53335 7 201 1.29E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS23950 e697310718df93e3627837138638db53 227 Pfam PF08241 Methyltransferase domain 52 147 6.5E-22 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS23950 e697310718df93e3627837138638db53 227 Gene3D G3DSA:3.40.50.150 2 199 1.3E-34 T 29-03-2018 A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 SUPERFAMILY SSF51735 3 111 6.22E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 7 206 9.6E-45 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 Pfam PF13241 Putative NAD(P)-binding 6 114 1.6E-30 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 Pfam PF14824 Sirohaem biosynthesis protein central 118 144 2.9E-11 T 29-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 SUPERFAMILY SSF75615 107 207 8.24E-20 T 29-03-2018 A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 Gene3D G3DSA:3.40.50.720 1 104 2.9E-16 T 29-03-2018 A616_RS07385 1ff0b7fc08b3319e4ea03dc731e409c2 213 Gene3D G3DSA:3.30.160.110 105 145 1.3E-20 T 29-03-2018 A616_RS15290 49576eb5003f82e1519d916c75be7e56 114 Gene3D G3DSA:1.10.10.10 17 113 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15290 49576eb5003f82e1519d916c75be7e56 114 SUPERFAMILY SSF46785 8 108 6.07E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15290 49576eb5003f82e1519d916c75be7e56 114 Pfam PF01638 HxlR-like helix-turn-helix 19 106 9.0E-38 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS09995 8623998182306d0818badb18f366034e 276 Gene3D G3DSA:3.40.50.620 2 268 6.5E-74 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS09995 8623998182306d0818badb18f366034e 276 PIRSF PIRSF000090 2 268 2.2E-86 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 A616_RS09995 8623998182306d0818badb18f366034e 276 SUPERFAMILY SSF52402 2 264 4.31E-73 T 29-03-2018 A616_RS09995 8623998182306d0818badb18f366034e 276 Pfam PF01012 Electron transfer flavoprotein domain 24 214 8.6E-45 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS09995 8623998182306d0818badb18f366034e 276 SMART SM00893 23 219 8.4E-55 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 Gene3D G3DSA:3.30.860.10 1 92 1.1E-40 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 Pfam PF00203 Ribosomal protein S19 3 83 1.6E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.9E-48 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 SUPERFAMILY SSF54570 3 83 1.26E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 PIRSF PIRSF002144 1 93 2.6E-33 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.647 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.0E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.0E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01420 fd5fba50c5b5206425acfe84127a598b 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.0E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 90.741 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 SUPERFAMILY SSF48557 3 457 4.4E-155 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 7.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 7.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 7.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 7.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 1.2E-237 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 Gene3D G3DSA:1.20.200.10 137 415 6.8E-86 T 29-03-2018 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 Gene3D G3DSA:1.10.275.10 1 136 6.0E-63 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 Pfam PF10415 Fumarase C C-terminus 406 459 3.0E-26 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 Pfam PF00206 Lyase 11 340 1.2E-116 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 Gene3D G3DSA:1.10.40.30 416 460 1.8E-27 T 29-03-2018 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 2.1E-5 T 29-03-2018 A616_RS31085 8c7df1ceeff7ed05fcbe6c5e891021c2 462 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 2.1E-5 T 29-03-2018 A616_RS08265 351740daed846cef65c924a4cc582ec6 325 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 322 1.9E-80 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A616_RS08265 351740daed846cef65c924a4cc582ec6 325 SUPERFAMILY SSF51395 6 322 1.18E-108 T 29-03-2018 A616_RS08265 351740daed846cef65c924a4cc582ec6 325 Gene3D G3DSA:3.20.20.70 2 324 6.6E-114 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS08140 216026528ec08c178886a9b497f67ada 571 SUPERFAMILY SSF55874 414 552 2.88E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08140 216026528ec08c178886a9b497f67ada 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 503 3.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08140 216026528ec08c178886a9b497f67ada 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 3.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08140 216026528ec08c178886a9b497f67ada 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 530 3.0E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08140 216026528ec08c178886a9b497f67ada 571 Pfam PF06580 Histidine kinase 359 437 8.4E-26 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS08140 216026528ec08c178886a9b497f67ada 571 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 457 554 5.2E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08140 216026528ec08c178886a9b497f67ada 571 Gene3D G3DSA:3.30.450.40 195 369 5.6E-5 T 29-03-2018 IPR029016 GAF domain-like A616_RS08140 216026528ec08c178886a9b497f67ada 571 Gene3D G3DSA:3.30.565.10 370 554 1.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08140 216026528ec08c178886a9b497f67ada 571 SMART SM00387 452 555 0.0048 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08140 216026528ec08c178886a9b497f67ada 571 Pfam PF07694 5TMR of 5TMR-LYT 28 190 9.4E-45 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A616_RS04890 293211a421158e2e85798f9f7eb9ec94 422 Gene3D G3DSA:3.40.50.1100 201 398 4.3E-42 T 29-03-2018 A616_RS04890 293211a421158e2e85798f9f7eb9ec94 422 PIRSF PIRSF038945 39 412 1.2E-107 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A616_RS04890 293211a421158e2e85798f9f7eb9ec94 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 79 381 9.8E-56 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS04890 293211a421158e2e85798f9f7eb9ec94 422 Gene3D G3DSA:3.40.50.1100 93 200 8.7E-20 T 29-03-2018 A616_RS04890 293211a421158e2e85798f9f7eb9ec94 422 TIGRFAM TIGR00260 thrC: threonine synthase 60 388 1.2E-69 T 29-03-2018 IPR004450 Threonine synthase-like A616_RS04890 293211a421158e2e85798f9f7eb9ec94 422 SUPERFAMILY SSF53686 2 397 3.67E-93 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Gene3D G3DSA:1.10.1790.10 200 299 1.9E-4 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Pfam PF00874 PRD domain 557 638 2.0E-4 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Pfam PF00874 PRD domain 323 411 6.8E-9 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 SUPERFAMILY SSF63520 314 411 1.27E-10 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Gene3D G3DSA:1.10.1790.10 312 416 2.4E-11 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Gene3D G3DSA:1.10.1790.10 545 638 6.0E-4 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Gene3D G3DSA:3.40.50.2300 419 507 2.0E-16 T 29-03-2018 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Pfam PF08279 HTH domain 95 152 8.8E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 SUPERFAMILY SSF63520 212 293 3.79E-5 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Gene3D G3DSA:1.10.10.10 3 68 3.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 Gene3D G3DSA:1.10.10.10 90 156 2.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 SUPERFAMILY SSF52794 423 499 1.57E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A616_RS18360 c2202a5f20f2673901d724d8683351b8 656 SUPERFAMILY SSF63520 551 637 3.79E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS07285 08f2c0c78ad4a5b834b9b44e9e119b93 230 Gene3D G3DSA:3.30.1380.10 26 224 2.0E-43 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS07285 08f2c0c78ad4a5b834b9b44e9e119b93 230 SUPERFAMILY SSF55166 23 221 1.44E-44 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS07285 08f2c0c78ad4a5b834b9b44e9e119b93 230 Pfam PF01427 D-ala-D-ala dipeptidase 59 219 6.8E-20 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A616_RS07285 08f2c0c78ad4a5b834b9b44e9e119b93 230 PIRSF PIRSF026671 2 227 2.0E-43 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A616_RS07285 08f2c0c78ad4a5b834b9b44e9e119b93 230 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 22 222 25.566 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SUPERFAMILY SSF143517 1015 1170 7.06E-34 T 29-03-2018 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Gene3D G3DSA:3.40.50.300 36 440 6.1E-5 T 29-03-2018 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Pfam PF00271 Helicase conserved C-terminal domain 830 931 7.7E-17 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SMART SM00490 848 932 1.6E-20 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SMART SM00487 622 812 3.3E-35 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Pfam PF00270 DEAD/DEAH box helicase 630 786 2.0E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SUPERFAMILY SSF52540 377 489 1.17E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Pfam PF03461 TRCF domain 1027 1120 1.5E-26 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SUPERFAMILY SSF52540 546 805 2.13E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SUPERFAMILY SSF52540 804 1012 5.87E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 42 1110 29.663 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SMART SM01058 501 598 3.2E-46 T 29-03-2018 IPR003711 CarD-like/TRCF domain A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Gene3D G3DSA:3.40.50.300 813 978 1.1E-26 T 29-03-2018 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1099 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SUPERFAMILY SSF141259 492 569 1.18E-23 T 29-03-2018 IPR003711 CarD-like/TRCF domain A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SUPERFAMILY SSF52540 17 367 1.08E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 SMART SM00982 1026 1127 1.7E-35 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Pfam PF02559 CarD-like/TRCF domain 502 597 7.8E-30 T 29-03-2018 IPR003711 CarD-like/TRCF domain A616_RS00705 a2ba419863d380ebcb9b797e658c5d2a 1182 Gene3D G3DSA:3.40.50.300 472 792 2.4E-40 T 29-03-2018 A616_RS02720 3aac5e9ef20bf94dc33aec7d0a0a028a 541 SUPERFAMILY SSF53850 41 535 9.77E-138 T 29-03-2018 A616_RS02720 3aac5e9ef20bf94dc33aec7d0a0a028a 541 Gene3D G3DSA:3.40.190.10 212 308 1.2E-20 T 29-03-2018 A616_RS02720 3aac5e9ef20bf94dc33aec7d0a0a028a 541 Gene3D G3DSA:3.90.76.10 53 211 3.5E-41 T 29-03-2018 A616_RS02720 3aac5e9ef20bf94dc33aec7d0a0a028a 541 PIRSF PIRSF002741 2 539 5.7E-135 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS02720 3aac5e9ef20bf94dc33aec7d0a0a028a 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 463 9.8E-88 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS02720 3aac5e9ef20bf94dc33aec7d0a0a028a 541 Gene3D G3DSA:3.10.105.10 309 515 3.5E-59 T 29-03-2018 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SUPERFAMILY SSF50249 205 623 7.42E-147 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SUPERFAMILY SSF50249 123 222 5.31E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Gene3D G3DSA:1.10.10.10 2 56 1.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Gene3D G3DSA:2.40.50.140 57 132 0.0011 T 29-03-2018 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 ProSitePatterns PS01175 Ribonuclease II family signature. 542 566 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SUPERFAMILY SSF50249 52 132 7.07E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 58 706 1.3E-234 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SMART SM00357 135 199 1.6E-6 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SMART SM00357 70 130 3.1E-14 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Pfam PF08206 Ribonuclease B OB domain 71 129 2.2E-20 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Pfam PF08206 Ribonuclease B OB domain 145 198 4.8E-10 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Pfam PF00575 S1 RNA binding domain 625 705 7.5E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SMART SM00955 245 575 1.6E-171 T 29-03-2018 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 TIGRFAM TIGR02063 RNase_R: ribonuclease R 2 706 5.0E-280 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Hamap MF_01895 Ribonuclease R [rnr]. 22 706 61.063 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SMART SM00316 624 706 3.7E-17 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Pfam PF00773 RNB domain 245 573 8.9E-110 T 29-03-2018 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 SUPERFAMILY SSF50249 624 704 1.34E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Gene3D G3DSA:2.40.50.140 133 281 0.0022 T 29-03-2018 A616_RS28970 4a6139ce75650c55cefb2ae53f313f6f 843 Gene3D G3DSA:2.40.50.140 623 707 2.5E-23 T 29-03-2018 A616_RS19485 2231db0767c389c1e501f923b0448b19 143 Gene3D G3DSA:3.10.180.10 2 143 9.8E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS19485 2231db0767c389c1e501f923b0448b19 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 135 2.4E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS19485 2231db0767c389c1e501f923b0448b19 143 SUPERFAMILY SSF54593 3 137 2.96E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15050 3a717ea8b2097c7562254de9881ea7f4 280 PIRSF PIRSF002854 1 264 1.3E-83 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS15050 3a717ea8b2097c7562254de9881ea7f4 280 Gene3D G3DSA:3.40.190.10 125 264 2.1E-42 T 29-03-2018 A616_RS15050 3a717ea8b2097c7562254de9881ea7f4 280 SUPERFAMILY SSF53850 29 265 1.41E-70 T 29-03-2018 A616_RS15050 3a717ea8b2097c7562254de9881ea7f4 280 Gene3D G3DSA:3.40.190.10 29 124 3.0E-16 T 29-03-2018 A616_RS15050 3a717ea8b2097c7562254de9881ea7f4 280 Pfam PF03180 NLPA lipoprotein 29 262 2.6E-76 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS20575 eab495a0372a700e825accaf1d2be228 476 Gene3D G3DSA:1.10.40.30 419 468 7.6E-21 T 29-03-2018 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 9 471 1.4E-241 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 Pfam PF10415 Fumarase C C-terminus 412 464 4.1E-20 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 Gene3D G3DSA:1.10.275.10 6 141 4.2E-54 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal A616_RS20575 eab495a0372a700e825accaf1d2be228 476 Gene3D G3DSA:1.20.200.10 142 418 2.3E-84 T 29-03-2018 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 Pfam PF00206 Lyase 16 345 1.8E-114 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal A616_RS20575 eab495a0372a700e825accaf1d2be228 476 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 7.4E-7 T 29-03-2018 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 7.4E-7 T 29-03-2018 A616_RS20575 eab495a0372a700e825accaf1d2be228 476 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 1.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS20575 eab495a0372a700e825accaf1d2be228 476 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 1.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS20575 eab495a0372a700e825accaf1d2be228 476 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 1.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS20575 eab495a0372a700e825accaf1d2be228 476 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 1.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS20575 eab495a0372a700e825accaf1d2be228 476 SUPERFAMILY SSF48557 8 465 5.01E-151 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Pfam PF09382 RQC domain 401 506 1.5E-35 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Pfam PF00271 Helicase conserved C-terminal domain 219 323 1.4E-17 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Gene3D G3DSA:3.40.50.300 205 346 3.5E-31 T 29-03-2018 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Pfam PF16124 RecQ zinc-binding 335 397 2.0E-15 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 456 6.5E-140 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 5 586 3.2E-244 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Gene3D G3DSA:1.10.10.10 347 507 3.4E-50 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SUPERFAMILY SSF52540 57 345 3.6E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Pfam PF00270 DEAD/DEAH box helicase 21 181 4.5E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SMART SM00341 513 591 3.7E-16 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SMART SM00490 243 324 8.7E-26 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Pfam PF00570 HRDC domain 517 583 9.0E-23 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SMART SM00956 405 508 3.8E-45 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Gene3D G3DSA:3.40.50.300 1 201 3.4E-32 T 29-03-2018 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SUPERFAMILY SSF46785 396 539 8.71E-39 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SUPERFAMILY SSF47819 515 588 1.1E-22 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 Gene3D G3DSA:1.10.150.80 508 591 1.8E-26 T 29-03-2018 A616_RS31050 dd89100e749ed8f8f1a4a0e2178ace80 591 SMART SM00487 14 211 6.0E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS14270 9124d3051481fc8c6b6d28135d67b94c 223 Gene3D G3DSA:3.40.630.30 1 164 9.2E-8 T 29-03-2018 A616_RS14270 9124d3051481fc8c6b6d28135d67b94c 223 SUPERFAMILY SSF55729 5 94 1.1E-6 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Pfam PF01330 RuvA N terminal domain 1 61 1.4E-19 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Gene3D G3DSA:1.10.340.30 52 80 0.53 T 29-03-2018 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Gene3D G3DSA:2.40.50.140 1 51 9.7E-21 T 29-03-2018 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Gene3D G3DSA:1.10.150.20 81 136 1.6E-15 T 29-03-2018 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 197 1.8E-52 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 SMART SM00278 72 91 2.4 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 SMART SM00278 107 126 0.14 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.7E-17 T 29-03-2018 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 SUPERFAMILY SSF47781 65 136 4.17E-22 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Pfam PF07499 RuvA, C-terminal domain 156 203 5.0E-10 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 203 29.872 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 SUPERFAMILY SSF50249 1 62 2.91E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 Gene3D G3DSA:1.10.8.10 137 203 2.4E-9 T 29-03-2018 A616_RS10655 2d3f49492ed9d1de248e99e21a3e87ec 205 SUPERFAMILY SSF46929 156 203 3.4E-7 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A616_RS31265 a31fbf8553029a4d0b3438a989e57685 597 Gene3D G3DSA:3.40.50.410 34 234 2.9E-32 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31265 a31fbf8553029a4d0b3438a989e57685 597 SMART SM00327 38 230 1.6E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31265 a31fbf8553029a4d0b3438a989e57685 597 SUPERFAMILY SSF53300 38 226 9.49E-27 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31265 a31fbf8553029a4d0b3438a989e57685 597 Pfam PF00092 von Willebrand factor type A domain 41 222 3.0E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00501 AMP-binding enzyme 1324 1726 1.9E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00501 AMP-binding enzyme 246 651 6.4E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF56801 227 770 2.49E-156 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF52777 849 1026 7.34E-43 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF52777 2106 2348 1.06E-59 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF47336 750 821 1.7E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.40.50.980 1315 1469 1.9E-44 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.40.50.980 237 392 2.6E-46 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SMART SM00823 Phosphopantetheine attachment site 758 827 0.0081 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SMART SM00823 Phosphopantetheine attachment site 1831 1900 1.5E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:2.30.38.10 1637 1716 4.3E-23 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:2.30.38.10 560 641 2.8E-24 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00668 Condensation domain 845 1304 5.4E-104 T 29-03-2018 IPR001242 Condensation domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00668 Condensation domain 1920 2365 1.9E-117 T 29-03-2018 IPR001242 Condensation domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00668 Condensation domain 155 224 1.3E-6 T 29-03-2018 IPR001242 Condensation domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00668 Condensation domain 3 88 8.6E-12 T 29-03-2018 IPR001242 Condensation domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:1.10.1200.10 762 830 3.4E-19 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1855 1870 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.40.50.980 393 559 1.2E-37 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.40.50.980 1470 1636 6.5E-39 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF52777 1922 2099 5.11E-51 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF56801 1283 1844 3.4E-159 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 ProSitePatterns PS00012 Phosphopantetheine attachment site. 782 797 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:1.10.1200.10 1837 1900 2.3E-22 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.30.300.30 1721 1836 2.3E-35 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.30.300.30 646 761 1.3E-29 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF47336 1823 1932 2.88E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF13193 AMP-binding enzyme C-terminal domain 1734 1805 2.6E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF13193 AMP-binding enzyme C-terminal domain 659 730 2.1E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1464 1475 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00550 Phosphopantetheine attachment site 1834 1895 7.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Pfam PF00550 Phosphopantetheine attachment site 760 820 1.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF52777 1034 1311 5.34E-57 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 SUPERFAMILY SSF52777 3 212 1.22E-21 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 266 674 1.3E-140 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1345 1749 4.5E-136 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 ProSitePatterns PS00455 Putative AMP-binding domain signature. 386 397 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.30.559.10 831 1029 4.3E-32 T 29-03-2018 A616_RS28675 bdeb6e8974157fc369d47970fc9bc781 2371 Gene3D G3DSA:3.30.559.10 1901 2108 3.1E-43 T 29-03-2018 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 Gene3D G3DSA:1.10.287.130 243 298 6.7E-14 T 29-03-2018 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 Gene3D G3DSA:3.30.565.10 305 458 3.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 SMART SM00304 181 232 3.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 SUPERFAMILY SSF158472 182 229 3.66E-6 T 29-03-2018 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 SMART SM00388 240 302 1.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 Gene3D G3DSA:1.20.120.330 33 242 5.8E-6 T 29-03-2018 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 SUPERFAMILY SSF55874 304 451 1.03E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 SUPERFAMILY SSF47384 224 302 1.96E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 SMART SM00387 347 457 1.0E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 Pfam PF00672 HAMP domain 181 229 1.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 446 2.7E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04455 481f37cf1f835e46bf4f3e1a7e1b9195 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 300 3.7E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 46 263 1.4E-72 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 PIRSF PIRSF004846 1 265 1.5E-88 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 Gene3D G3DSA:3.40.190.10 135 214 3.4E-35 T 29-03-2018 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 Pfam PF13531 Bacterial extracellular solute-binding protein 43 265 3.3E-52 T 29-03-2018 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 Gene3D G3DSA:3.40.190.10 37 134 7.8E-20 T 29-03-2018 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 SUPERFAMILY SSF53850 40 264 1.61E-68 T 29-03-2018 A616_RS12880 6ea22ef0482c2771fe940d6758ef77c3 265 Gene3D G3DSA:3.40.190.10 215 265 1.5E-4 T 29-03-2018 A616_RS09110 446b49222c71e0394c733b31362db98f 438 SUPERFAMILY SSF56601 2 339 3.98E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS09110 446b49222c71e0394c733b31362db98f 438 Pfam PF00144 Beta-lactamase 10 326 4.2E-71 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS09110 446b49222c71e0394c733b31362db98f 438 Gene3D G3DSA:3.40.710.10 1 339 3.8E-82 T 29-03-2018 A616_RS17360 51586e9bd4e8969b4d51bc8dcf4b0d78 528 Gene3D G3DSA:1.10.238.10 20 413 0.0023 T 29-03-2018 A616_RS09665 fea9b6fcef0006f7b5df2e4fb7460026 458 SUPERFAMILY SSF56801 109 443 2.2E-19 T 29-03-2018 A616_RS09665 fea9b6fcef0006f7b5df2e4fb7460026 458 Gene3D G3DSA:3.40.50.980 96 280 3.0E-10 T 29-03-2018 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 Pfam PF00849 RNA pseudouridylate synthase 65 196 2.6E-17 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 Pfam PF01479 S4 domain 4 44 5.9E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 SMART SM00363 4 62 5.3E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 Gene3D G3DSA:3.30.70.580 73 145 5.4E-19 T 29-03-2018 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 102 116 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 69 228 3.2E-50 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 Gene3D G3DSA:3.30.70.1560 146 213 1.3E-24 T 29-03-2018 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 Gene3D G3DSA:3.10.290.10 1 72 4.9E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 SUPERFAMILY SSF55174 5 60 7.85E-11 T 29-03-2018 A616_RS00395 c64699992cbe85aecab0343de7728e50 239 SUPERFAMILY SSF55120 64 231 1.92E-46 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS11135 f8511fe3de4a13c1a8524a8ebdcfa55c 252 Pfam PF16285 Domain of unknown function (DUF4931) 8 252 5.2E-126 T 29-03-2018 A616_RS11135 f8511fe3de4a13c1a8524a8ebdcfa55c 252 SUPERFAMILY SSF54197 15 129 1.89E-21 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS11135 f8511fe3de4a13c1a8524a8ebdcfa55c 252 PIRSF PIRSF031505 1 252 2.0E-92 T 29-03-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative A616_RS11135 f8511fe3de4a13c1a8524a8ebdcfa55c 252 Gene3D G3DSA:3.30.428.10 55 130 1.8E-14 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS21800 0c47213b712683ea19ec8ee1ad6123b4 188 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 181 1.1E-57 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS21800 0c47213b712683ea19ec8ee1ad6123b4 188 Gene3D G3DSA:3.40.50.300 2 182 9.6E-61 T 29-03-2018 A616_RS21800 0c47213b712683ea19ec8ee1ad6123b4 188 SUPERFAMILY SSF52540 2 182 5.49E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21800 0c47213b712683ea19ec8ee1ad6123b4 188 PIRSF PIRSF006135 1 184 4.5E-55 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS21715 06655c37fdfe5a32c79244cb1d03cfab 154 Pfam PF12867 DinB superfamily 11 143 1.8E-17 T 29-03-2018 IPR024775 DinB-like domain A616_RS21715 06655c37fdfe5a32c79244cb1d03cfab 154 SUPERFAMILY SSF109854 6 153 2.01E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS21715 06655c37fdfe5a32c79244cb1d03cfab 154 Gene3D G3DSA:1.20.120.450 1 150 5.2E-25 T 29-03-2018 A616_RS19055 100178f4263ab559878a4391691a70fa 749 Pfam PF13538 UvrD-like helicase C-terminal domain 686 724 6.2E-7 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain A616_RS19055 100178f4263ab559878a4391691a70fa 749 Gene3D G3DSA:3.40.50.300 193 563 9.3E-35 T 29-03-2018 A616_RS19055 100178f4263ab559878a4391691a70fa 749 Gene3D G3DSA:3.40.50.300 570 749 9.5E-24 T 29-03-2018 A616_RS19055 100178f4263ab559878a4391691a70fa 749 SUPERFAMILY SSF52540 188 351 4.9E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19055 100178f4263ab559878a4391691a70fa 749 SUPERFAMILY SSF52540 479 734 4.9E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19055 100178f4263ab559878a4391691a70fa 749 Pfam PF13245 AAA domain 199 545 2.8E-11 T 29-03-2018 A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 Gene3D G3DSA:3.60.20.10 1 220 1.3E-61 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 Pfam PF13537 Glutamine amidotransferase domain 48 165 7.3E-48 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 567 5.6E-151 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 Pfam PF00733 Asparagine synthase 242 627 3.1E-89 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 PIRSF PIRSF001589 1 632 1.6E-172 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 Gene3D G3DSA:3.40.50.620 221 631 1.0E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 SUPERFAMILY SSF56235 1 223 2.4E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 SUPERFAMILY SSF52402 229 383 2.17E-69 T 29-03-2018 A616_RS29675 dd8a2b4684173b528dcaa4f757beea17 632 SUPERFAMILY SSF52402 486 616 2.17E-69 T 29-03-2018 A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 SUPERFAMILY SSF46689 2 80 1.23E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 Gene3D G3DSA:1.10.10.60 1 61 7.5E-13 T 29-03-2018 A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 Gene3D G3DSA:1.10.357.10 62 194 2.2E-24 T 29-03-2018 A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 1.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 SUPERFAMILY SSF48498 77 192 1.76E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09050 3742671da67ca4b2fd27c3b4fb538301 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 Gene3D G3DSA:3.40.640.10 135 375 1.4E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 Gene3D G3DSA:3.90.1150.10 376 480 1.3E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 SUPERFAMILY SSF53383 147 478 1.66E-49 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 Pfam PF00155 Aminotransferase class I and II 143 474 4.0E-15 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 5.7E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 Gene3D G3DSA:1.10.10.10 6 96 5.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 SUPERFAMILY SSF46785 13 92 6.12E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09505 658978150bbce37660725cb9ea1f2a7c 480 SMART SM00345 23 83 1.2E-4 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 Pfam PF04542 Sigma-70 region 2 15 77 1.3E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 Gene3D G3DSA:1.10.1740.10 3 82 3.8E-13 T 29-03-2018 A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 SUPERFAMILY SSF88946 14 92 5.49E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 157 7.2E-14 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 Gene3D G3DSA:1.10.10.10 92 192 1.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 Gene3D G3DSA:3.10.180.10 193 250 3.3E-5 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 SUPERFAMILY SSF54593 196 249 3.47E-6 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS23360 54344c081be0bab2a6c2be63d745ce38 250 SUPERFAMILY SSF88659 101 158 1.08E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS16265 41a2f3f11c6f098208c3f17a86dd5f22 289 PIRSF PIRSF016184 1 289 2.7E-78 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A616_RS16265 41a2f3f11c6f098208c3f17a86dd5f22 289 Gene3D G3DSA:3.10.310.10 126 278 4.1E-35 T 29-03-2018 A616_RS16265 41a2f3f11c6f098208c3f17a86dd5f22 289 Gene3D G3DSA:3.10.310.10 1 125 2.4E-28 T 29-03-2018 A616_RS16265 41a2f3f11c6f098208c3f17a86dd5f22 289 SUPERFAMILY SSF54506 2 287 3.14E-67 T 29-03-2018 A616_RS16265 41a2f3f11c6f098208c3f17a86dd5f22 289 Pfam PF02567 Phenazine biosynthesis-like protein 9 284 1.1E-61 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A616_RS16265 41a2f3f11c6f098208c3f17a86dd5f22 289 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 288 2.0E-66 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 Gene3D G3DSA:3.50.50.60 2 133 6.3E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 Gene3D G3DSA:3.50.50.60 134 279 4.3E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 SUPERFAMILY SSF51905 3 260 1.66E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 195 273 2.6E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 164 2.0E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 257 2.7E-16 T 29-03-2018 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.7E-16 T 29-03-2018 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.7E-16 T 29-03-2018 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.7E-16 T 29-03-2018 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 224 2.7E-16 T 29-03-2018 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 263 1.0E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 1.0E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS23730 45d1ee86234924bf7a7385e80ca64989 279 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 1.0E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 Gene3D G3DSA:3.40.50.1100 41 139 3.0E-35 T 29-03-2018 A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 Gene3D G3DSA:3.40.50.1100 140 306 3.0E-56 T 29-03-2018 A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 SUPERFAMILY SSF53686 3 301 1.1E-94 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 1.1E-105 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 1.6E-105 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A616_RS26400 c1e17673164300ee5b71b6979aa1a36f 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 291 5.1E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS19070 3b123216b4b8b4c4f1e495ab0d9e8e21 111 SUPERFAMILY SSF54106 58 108 4.97E-8 T 29-03-2018 IPR018392 LysM domain A616_RS19070 3b123216b4b8b4c4f1e495ab0d9e8e21 111 Pfam PF01476 LysM domain 59 108 3.3E-11 T 29-03-2018 IPR018392 LysM domain A616_RS19070 3b123216b4b8b4c4f1e495ab0d9e8e21 111 SMART SM00257 58 108 1.6E-11 T 29-03-2018 IPR018392 LysM domain A616_RS19070 3b123216b4b8b4c4f1e495ab0d9e8e21 111 Gene3D G3DSA:3.10.350.10 51 111 8.1E-15 T 29-03-2018 A616_RS15685 68f81acdb98e4645f813d72b89e3617b 235 Gene3D G3DSA:3.90.470.20 112 207 2.9E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS15685 68f81acdb98e4645f813d72b89e3617b 235 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 103 215 1.2E-14 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A616_RS15685 68f81acdb98e4645f813d72b89e3617b 235 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 104 206 4.2E-16 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS15685 68f81acdb98e4645f813d72b89e3617b 235 SUPERFAMILY SSF56214 10 97 3.92E-24 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS15685 68f81acdb98e4645f813d72b89e3617b 235 Gene3D G3DSA:3.90.470.20 2 111 7.2E-24 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS15685 68f81acdb98e4645f813d72b89e3617b 235 SUPERFAMILY SSF56214 104 225 3.27E-29 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS03990 714ed18e6b986026bb549505b486d270 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 1.2E-242 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 A616_RS03990 714ed18e6b986026bb549505b486d270 515 Gene3D G3DSA:3.40.605.10 23 301 1.3E-82 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS03990 714ed18e6b986026bb549505b486d270 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS03990 714ed18e6b986026bb549505b486d270 515 Gene3D G3DSA:3.40.309.10 302 490 7.5E-63 T 29-03-2018 A616_RS03990 714ed18e6b986026bb549505b486d270 515 SUPERFAMILY SSF53720 4 512 2.49E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS03990 714ed18e6b986026bb549505b486d270 515 Pfam PF00171 Aldehyde dehydrogenase family 50 511 1.6E-155 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 Gene3D G3DSA:1.10.287.130 240 319 3.9E-13 T 29-03-2018 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 476 7.5E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 SUPERFAMILY SSF55874 326 476 5.76E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 SMART SM00304 197 249 1.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 SMART SM00387 366 478 4.8E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 Pfam PF00672 HAMP domain 197 245 2.4E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 SUPERFAMILY SSF158472 197 246 1.44E-9 T 29-03-2018 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 SMART SM00388 257 323 4.6E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 323 7.9E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 3.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 456 3.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 3.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 3.4E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 Gene3D G3DSA:3.30.565.10 326 480 5.7E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23970 4048d459f1fe1e75db4c74ab73b1f879 480 SUPERFAMILY SSF47384 240 324 1.06E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS10595 ba2dac5d132446dfb80d5760ee5d1647 147 Gene3D G3DSA:3.30.70.260 66 143 4.2E-7 T 29-03-2018 A616_RS10595 ba2dac5d132446dfb80d5760ee5d1647 147 SUPERFAMILY SSF55021 71 143 2.72E-7 T 29-03-2018 A616_RS10595 ba2dac5d132446dfb80d5760ee5d1647 147 Hamap MF_00707 UPF0735 ACT domain-containing protein . 3 147 31.104 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein A616_RS10595 ba2dac5d132446dfb80d5760ee5d1647 147 PIRSF PIRSF025624 1 147 1.3E-52 T 29-03-2018 IPR008310 UPF0735 ACT domain-containing protein A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 Pfam PF13396 Phospholipase_D-nuclease N-terminal 17 55 4.8E-11 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 3 482 2.1E-176 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 SUPERFAMILY SSF56024 91 311 3.59E-53 T 29-03-2018 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 SMART SM00155 217 244 6.6E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 SMART SM00155 395 422 0.0033 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 Pfam PF13091 PLD-like domain 136 266 9.0E-13 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 Pfam PF13091 PLD-like domain 324 447 1.9E-25 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 SUPERFAMILY SSF56024 269 469 7.85E-50 T 29-03-2018 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 Gene3D G3DSA:3.30.870.10 309 464 4.2E-30 T 29-03-2018 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 Hamap MF_01916 Cardiolipin synthase. 9 482 43.221 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 A616_RS30640 1bcdd435a1f4df9aa50d2a2f580ac1c4 482 Gene3D G3DSA:3.30.870.10 108 306 2.4E-34 T 29-03-2018 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 PIRSF PIRSF001435 1 214 6.5E-59 T 29-03-2018 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 ProSitePatterns PS01155 Endonuclease III family signature. 104 133 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 1.8E-21 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 Pfam PF00633 Helix-hairpin-helix motif 102 129 3.8E-9 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 Gene3D G3DSA:1.10.340.30 27 119 1.5E-27 T 29-03-2018 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 SMART SM00478 40 187 1.8E-59 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.31 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 SUPERFAMILY SSF48150 11 208 1.4E-72 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 Gene3D G3DSA:1.10.1670.10 120 222 6.6E-36 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A616_RS05995 c508ce44e9ae516fa8a75aeeed93a8b0 227 TIGRFAM TIGR01083 nth: endonuclease III 9 196 3.3E-83 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A616_RS26660 410d752297d8650e357611769c5b7a05 168 Gene3D G3DSA:3.40.140.10 15 148 2.5E-15 T 29-03-2018 A616_RS26660 410d752297d8650e357611769c5b7a05 168 Pfam PF14464 Prokaryotic homologs of the JAB domain 22 129 7.8E-14 T 29-03-2018 IPR028090 JAB domain, prokaryotic A616_RS26660 410d752297d8650e357611769c5b7a05 168 SUPERFAMILY SSF102712 18 136 3.92E-23 T 29-03-2018 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 Pfam PF12831 FAD dependent oxidoreductase 8 439 3.4E-124 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 Gene3D G3DSA:3.50.50.60 6 421 6.2E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 69 79 1.3E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.3E-5 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 SUPERFAMILY SSF51905 209 246 6.74E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 SUPERFAMILY SSF51905 369 420 6.74E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25520 b1da1c7182984d2fbac821bb2c7d6163 447 SUPERFAMILY SSF51905 5 168 6.74E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS04510 3c434a9cb6511c9fd146941ae90874c2 483 Gene3D G3DSA:3.20.20.370 265 482 4.8E-52 T 29-03-2018 A616_RS04510 3c434a9cb6511c9fd146941ae90874c2 483 Gene3D G3DSA:3.20.20.370 22 258 2.5E-36 T 29-03-2018 A616_RS04510 3c434a9cb6511c9fd146941ae90874c2 483 SUPERFAMILY SSF88713 48 249 5.12E-36 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS04510 3c434a9cb6511c9fd146941ae90874c2 483 SUPERFAMILY SSF88713 279 478 1.42E-55 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS04510 3c434a9cb6511c9fd146941ae90874c2 483 Pfam PF01522 Polysaccharide deacetylase 285 407 2.0E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS04510 3c434a9cb6511c9fd146941ae90874c2 483 Pfam PF01522 Polysaccharide deacetylase 60 180 5.9E-22 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 1.5E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 Gene3D G3DSA:3.40.50.2300 56 172 2.8E-26 T 29-03-2018 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 SMART SM00354 1 71 1.7E-24 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 Pfam PF13377 Periplasmic binding protein-like domain 167 327 1.6E-25 T 29-03-2018 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 Gene3D G3DSA:3.40.50.2300 173 302 1.1E-29 T 29-03-2018 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 SUPERFAMILY SSF53822 58 307 1.46E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 SUPERFAMILY SSF47413 2 59 9.85E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS04785 33ee00389ff261901cdbd3db18372cba 327 Gene3D G3DSA:1.10.260.40 3 55 1.6E-19 T 29-03-2018 A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 1.0E-25 T 29-03-2018 IPR020603 MraZ domain A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 70 9.1E-23 T 29-03-2018 IPR020603 MraZ domain A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 1.0E-58 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 SUPERFAMILY SSF89447 2 136 3.07E-54 T 29-03-2018 A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 143 1.0E-55 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 60.063 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 Gene3D G3DSA:2.10.260.10 3 57 1.8E-7 T 29-03-2018 A616_RS21340 eec64d724e3348c91bbce12393c884ea 143 Gene3D G3DSA:2.10.260.10 74 124 2.5E-7 T 29-03-2018 A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 SUPERFAMILY SSF47384 483 562 1.02E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 Gene3D G3DSA:1.10.287.130 486 556 3.3E-17 T 29-03-2018 A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 SMART SM00387 608 717 3.2E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 SUPERFAMILY SSF55874 551 701 1.43E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 SMART SM00388 496 562 4.1E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 Gene3D G3DSA:3.30.565.10 557 710 1.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 562 6.9E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 615 700 2.4E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 673 2.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS30980 2d0b1bb117c1474752e638ba5f2c566f 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 696 2.8E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 PIRSF PIRSF037846 14 367 1.1E-93 T 29-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 SUPERFAMILY SSF53187 192 367 4.08E-48 T 29-03-2018 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 SMART SM00646 255 363 2.9E-30 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 Gene3D G3DSA:2.40.50.110 23 92 1.3E-18 T 29-03-2018 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 Pfam PF08239 Bacterial SH3 domain 41 90 3.0E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 Pfam PF08239 Bacterial SH3 domain 121 171 1.4E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 SMART SM00287 112 175 4.6E-15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 SMART SM00287 33 93 1.9E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 SUPERFAMILY SSF50044 136 179 2.85E-6 T 29-03-2018 IPR001452 SH3 domain GO:0005515 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 Gene3D G3DSA:2.30.30.410 93 180 6.3E-19 T 29-03-2018 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 Gene3D G3DSA:3.40.630.40 181 368 2.8E-53 T 29-03-2018 A616_RS21785 a119b61f2570bef621da8ae86895cf0e 368 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 194 363 2.1E-45 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS14850 e33d1be35df5c0dc29ee2bcb3f277645 350 SUPERFAMILY SSF52540 21 340 1.41E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14850 e33d1be35df5c0dc29ee2bcb3f277645 350 Pfam PF03308 ArgK protein 39 310 1.0E-99 T 29-03-2018 A616_RS14850 e33d1be35df5c0dc29ee2bcb3f277645 350 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 35 339 1.7E-98 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14850 e33d1be35df5c0dc29ee2bcb3f277645 350 Gene3D G3DSA:1.20.5.170 18 68 3.0E-19 T 29-03-2018 A616_RS14850 e33d1be35df5c0dc29ee2bcb3f277645 350 Gene3D G3DSA:3.40.50.300 69 279 3.4E-32 T 29-03-2018 A616_RS14850 e33d1be35df5c0dc29ee2bcb3f277645 350 Gene3D G3DSA:1.10.287.130 281 342 4.8E-20 T 29-03-2018 A616_RS11220 df8cbe3984641adf709c6d992743d94b 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 4.6E-23 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A616_RS11220 df8cbe3984641adf709c6d992743d94b 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 2.0E-26 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A616_RS11220 df8cbe3984641adf709c6d992743d94b 96 SUPERFAMILY SSF75471 1 95 2.09E-31 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A616_RS11220 df8cbe3984641adf709c6d992743d94b 96 Gene3D G3DSA:3.30.110.60 1 96 3.4E-29 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A616_RS11220 df8cbe3984641adf709c6d992743d94b 96 SMART SM01103 2 85 3.2E-42 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A616_RS11220 df8cbe3984641adf709c6d992743d94b 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.3E-39 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 A616_RS21675 56f7113f6439661fe295ea3681cc635d 266 SUPERFAMILY SSF53335 5 188 6.5E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS21675 56f7113f6439661fe295ea3681cc635d 266 Gene3D G3DSA:3.40.50.150 18 255 3.8E-46 T 29-03-2018 A616_RS21675 56f7113f6439661fe295ea3681cc635d 266 Pfam PF13847 Methyltransferase domain 35 130 4.7E-18 T 29-03-2018 IPR025714 Methyltransferase domain A616_RS23640 8afb5d66303cc700b5ece5aeede399e7 187 Pfam PF14136 Domain of unknown function (DUF4303) 12 169 1.0E-30 T 29-03-2018 IPR025409 Protein of unknown function DUF4303 A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 10 306 6.8E-73 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 187 306 2.2E-35 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 Gene3D G3DSA:1.10.1040.10 186 318 2.7E-39 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 SUPERFAMILY SSF51735 9 175 5.67E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 Gene3D G3DSA:3.40.50.720 7 172 3.4E-26 T 29-03-2018 A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 SUPERFAMILY SSF48179 187 306 5.1E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS21380 4fe4c7fd10cb535c868b5354c3baa14b 321 Pfam PF02558 Ketopantoate reductase PanE/ApbA 10 158 8.6E-29 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 684 697 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 733 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 608 630 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 654 677 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 745 756 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 829 842 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 631 646 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 799 815 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 PRINTS PR00868 DNA-polymerase family A (pol I) signature 767 778 1.9E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SUPERFAMILY SSF88723 2 169 2.75E-52 T 29-03-2018 IPR029060 PIN domain-like A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Gene3D G3DSA:1.20.1060.10 497 609 8.7E-32 T 29-03-2018 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SUPERFAMILY SSF56672 476 882 2.89E-159 T 29-03-2018 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SMART SM00475 2 261 1.6E-136 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SMART SM00279 172 207 1.2E-17 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SMART SM00474 303 472 1.4E-11 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Gene3D G3DSA:3.40.50.1010 2 183 6.6E-67 T 29-03-2018 IPR029060 PIN domain-like A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Gene3D G3DSA:3.30.70.370 708 882 1.0E-52 T 29-03-2018 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Gene3D G3DSA:3.30.70.370 610 698 6.0E-17 T 29-03-2018 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Gene3D G3DSA:1.10.150.20 184 262 1.0E-29 T 29-03-2018 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SUPERFAMILY SSF47807 171 285 1.48E-32 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SMART SM00482 639 846 3.5E-125 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 TIGRFAM TIGR00593 pola: DNA polymerase I 5 882 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 ProSitePatterns PS00447 DNA polymerase family A signature. 708 727 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 169 4.2E-54 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Pfam PF00476 DNA polymerase family A 504 880 1.7E-160 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 SUPERFAMILY SSF53098 314 474 2.12E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 263 2.9E-33 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A616_RS08070 f34cf21765eecab1afc22cad04d1f9ea 882 Gene3D G3DSA:3.30.420.10 302 496 1.4E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:3.30.300.30 857 976 1.1E-36 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:3.40.50.980 461 617 4.7E-45 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Pfam PF13193 AMP-binding enzyme C-terminal domain 870 943 1.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 SMART SM00823 Phosphopantetheine attachment site 970 1038 0.0031 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 SUPERFAMILY SSF52777 12 189 3.0E-42 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Pfam PF00550 Phosphopantetheine attachment site 972 1034 2.3E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:1.10.1200.10 977 1050 1.3E-21 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 ProSitePatterns PS00012 Phosphopantetheine attachment site. 994 1009 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:3.40.50.980 618 770 6.7E-34 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:2.30.38.10 772 852 3.4E-23 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 ProSitePatterns PS00455 Putative AMP-binding domain signature. 612 623 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 SUPERFAMILY SSF52777 191 456 2.33E-52 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:3.30.559.10 1141 1346 6.9E-11 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Gene3D G3DSA:3.30.559.10 4 211 6.1E-34 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 886 1.0E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Pfam PF00668 Condensation domain 1184 1336 1.1E-12 T 29-03-2018 IPR001242 Condensation domain A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Pfam PF00668 Condensation domain 7 449 1.9E-113 T 29-03-2018 IPR001242 Condensation domain A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 Pfam PF00501 AMP-binding enzyme 470 862 5.6E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 SUPERFAMILY SSF47336 964 1034 5.23E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 SUPERFAMILY SSF56801 427 983 5.76E-157 T 29-03-2018 A616_RS18825 768cf678ca071a4c56fff703b7dc44ab 1574 SUPERFAMILY SSF52777 1168 1335 4.22E-17 T 29-03-2018 A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 Gene3D G3DSA:3.40.50.10090 1 48 9.6E-10 T 29-03-2018 A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 Gene3D G3DSA:3.40.50.720 49 261 5.6E-54 T 29-03-2018 A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 258 4.6E-57 T 29-03-2018 A616_RS14075 9d387f7e7b272b493c8c8e2c9500f6c0 262 SUPERFAMILY SSF51735 6 258 7.68E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09600 61783babcf18c76419f25a301f967045 785 Pfam PF00488 MutS domain V 330 511 1.6E-35 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS09600 61783babcf18c76419f25a301f967045 785 SUPERFAMILY SSF48334 18 287 4.19E-25 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS09600 61783babcf18c76419f25a301f967045 785 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 784 21.511 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A616_RS09600 61783babcf18c76419f25a301f967045 785 SMART SM00533 10 314 5.5E-22 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A616_RS09600 61783babcf18c76419f25a301f967045 785 SUPERFAMILY SSF52540 291 514 5.54E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09600 61783babcf18c76419f25a301f967045 785 SUPERFAMILY SSF160443 709 781 2.62E-8 T 29-03-2018 IPR002625 Smr domain A616_RS09600 61783babcf18c76419f25a301f967045 785 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 785 7.7E-247 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A616_RS09600 61783babcf18c76419f25a301f967045 785 Pfam PF01713 Smr domain 710 785 1.0E-18 T 29-03-2018 IPR002625 Smr domain A616_RS09600 61783babcf18c76419f25a301f967045 785 SMART SM00534 327 512 1.6E-70 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS09600 61783babcf18c76419f25a301f967045 785 Gene3D G3DSA:3.40.50.300 503 718 0.044 T 29-03-2018 A616_RS09600 61783babcf18c76419f25a301f967045 785 Gene3D G3DSA:1.20.120.330 110 303 0.19 T 29-03-2018 A616_RS09600 61783babcf18c76419f25a301f967045 785 SMART SM00463 707 785 1.0E-13 T 29-03-2018 IPR002625 Smr domain A616_RS09600 61783babcf18c76419f25a301f967045 785 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 409 425 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A616_RS09600 61783babcf18c76419f25a301f967045 785 Gene3D G3DSA:3.40.50.300 304 502 1.4E-33 T 29-03-2018 A616_RS09600 61783babcf18c76419f25a301f967045 785 PIRSF PIRSF005814 1 785 6.4E-265 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 A616_RS15400 b3d299789092dabe5aa9dc51ce59620d 126 SUPERFAMILY SSF54637 2 122 7.88E-26 T 29-03-2018 IPR029069 HotDog domain A616_RS15400 b3d299789092dabe5aa9dc51ce59620d 126 Pfam PF01575 MaoC like domain 2 99 5.8E-21 T 29-03-2018 IPR002539 MaoC-like domain A616_RS15400 b3d299789092dabe5aa9dc51ce59620d 126 Gene3D G3DSA:3.10.129.10 1 125 3.2E-26 T 29-03-2018 A616_RS08450 105354e367f0f21b9923a006b72ce558 281 Pfam PF00561 alpha/beta hydrolase fold 25 259 4.9E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS08450 105354e367f0f21b9923a006b72ce558 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS08450 105354e367f0f21b9923a006b72ce558 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 2.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS08450 105354e367f0f21b9923a006b72ce558 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS08450 105354e367f0f21b9923a006b72ce558 281 SUPERFAMILY SSF53474 3 275 2.11E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS08450 105354e367f0f21b9923a006b72ce558 281 Gene3D G3DSA:3.40.50.1820 1 278 1.9E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS10210 21bd549cd5d0a15921de3733c9ed7da1 305 PIRSF PIRSF016184 1 298 3.1E-85 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A616_RS10210 21bd549cd5d0a15921de3733c9ed7da1 305 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 295 4.6E-74 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A616_RS10210 21bd549cd5d0a15921de3733c9ed7da1 305 SUPERFAMILY SSF54506 4 296 3.6E-68 T 29-03-2018 A616_RS10210 21bd549cd5d0a15921de3733c9ed7da1 305 Pfam PF02567 Phenazine biosynthesis-like protein 9 293 9.3E-76 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 A616_RS10210 21bd549cd5d0a15921de3733c9ed7da1 305 Gene3D G3DSA:3.10.310.10 134 287 1.3E-40 T 29-03-2018 A616_RS10210 21bd549cd5d0a15921de3733c9ed7da1 305 Gene3D G3DSA:3.10.310.10 1 133 4.8E-33 T 29-03-2018 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 Gene3D G3DSA:3.30.450.20 6 140 2.3E-14 T 29-03-2018 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 Gene3D G3DSA:1.10.10.60 401 469 2.0E-10 T 29-03-2018 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 SUPERFAMILY SSF55785 14 119 6.63E-10 T 29-03-2018 IPR000014 PAS domain A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 Gene3D G3DSA:3.40.50.300 154 330 2.6E-26 T 29-03-2018 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 SUPERFAMILY SSF52540 159 399 7.84E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 SMART SM00382 179 322 3.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 Pfam PF08448 PAS fold 24 125 1.1E-5 T 29-03-2018 IPR013656 PAS fold-4 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 Gene3D G3DSA:1.10.8.60 331 400 3.1E-22 T 29-03-2018 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 132 3.0E-9 T 29-03-2018 IPR000014 PAS domain A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 183 196 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 Pfam PF00158 Sigma-54 interaction domain 160 324 5.0E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS15245 0bbb0d31e421be34ba668cdd304557fb 469 SUPERFAMILY SSF46689 370 462 4.3E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31060 22c0cffffaadb2da70e63527b4d44793 181 Pfam PF04892 VanZ like family 22 167 1.0E-30 T 29-03-2018 IPR006976 VanZ-like A616_RS09305 77462dbca46d909e7642829d41ee0cca 548 Gene3D G3DSA:3.40.190.10 176 310 3.0E-44 T 29-03-2018 A616_RS09305 77462dbca46d909e7642829d41ee0cca 548 PIRSF PIRSF002741 5 537 5.2E-132 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS09305 77462dbca46d909e7642829d41ee0cca 548 Gene3D G3DSA:3.10.105.10 311 504 7.9E-59 T 29-03-2018 A616_RS09305 77462dbca46d909e7642829d41ee0cca 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 452 1.4E-100 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS09305 77462dbca46d909e7642829d41ee0cca 548 SUPERFAMILY SSF53850 53 533 2.99E-148 T 29-03-2018 A616_RS09305 77462dbca46d909e7642829d41ee0cca 548 Gene3D G3DSA:3.90.76.10 74 175 3.2E-29 T 29-03-2018 A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 SUPERFAMILY SSF51735 4 242 6.41E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 240 4.1E-50 T 29-03-2018 A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 Gene3D G3DSA:3.40.50.720 1 159 1.1E-37 T 29-03-2018 A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 9.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21880 bb1ab39779d107370e3b36f22e77bd66 244 Gene3D G3DSA:3.40.50.720 160 241 9.4E-19 T 29-03-2018 A616_RS31570 935711e8345173707aac777f8d135bc0 113 Pfam PF00893 Small Multidrug Resistance protein 8 99 3.2E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS31570 935711e8345173707aac777f8d135bc0 113 SUPERFAMILY SSF103481 12 110 7.85E-20 T 29-03-2018 A616_RS00525 a2d5e419d55eb5bc48ce2f15c0f170d3 157 SUPERFAMILY SSF55961 1 150 6.32E-22 T 29-03-2018 A616_RS00525 a2d5e419d55eb5bc48ce2f15c0f170d3 157 Gene3D G3DSA:3.30.530.20 1 153 1.2E-18 T 29-03-2018 IPR023393 START-like domain A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 64 79 2.1E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 15 35 2.1E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 Gene3D G3DSA:3.40.50.300 48 190 3.0E-23 T 29-03-2018 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 Hamap MF_00367 GTPase Era [era]. 10 301 38.456 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 SUPERFAMILY SSF52540 15 210 1.04E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 TIGRFAM TIGR00436 era: GTP-binding protein Era 13 284 3.1E-105 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 SUPERFAMILY SSF54814 186 301 2.7E-43 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 Gene3D G3DSA:3.40.50.300 3 47 7.9E-10 T 29-03-2018 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 Gene3D G3DSA:3.30.300.20 191 304 7.3E-46 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 Pfam PF07650 KH domain 212 290 1.6E-20 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 171 7.0E-31 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS11650 2f1d46748fe818ac1c29c75e9f508f28 305 Pfam PF01926 50S ribosome-binding GTPase 15 129 1.9E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 SUPERFAMILY SSF63867 336 408 2.35E-12 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Gene3D G3DSA:2.40.340.10 336 411 8.6E-11 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Gene3D G3DSA:2.170.190.11 63 149 4.5E-28 T 29-03-2018 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 SUPERFAMILY SSF63882 7 182 9.29E-52 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 SUPERFAMILY SSF53218 185 330 1.44E-34 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Pfam PF00994 Probable molybdopterin binding domain 189 325 5.5E-18 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Gene3D G3DSA:3.40.980.10 158 333 3.1E-45 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Pfam PF03454 MoeA C-terminal region (domain IV) 339 408 4.1E-10 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Gene3D G3DSA:3.90.105.10 26 62 6.8E-7 T 29-03-2018 A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 SMART SM00852 188 326 3.9E-33 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 320 5.6E-27 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS06820 4c3767a62af6ef0758109841a7e3acd5 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 175 7.9E-44 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS19245 87d73ac1999bc692101e32414e3cbb14 397 SUPERFAMILY SSF103473 11 393 7.06E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS19245 87d73ac1999bc692101e32414e3cbb14 397 Gene3D G3DSA:1.20.1250.20 7 198 5.2E-21 T 29-03-2018 A616_RS19245 87d73ac1999bc692101e32414e3cbb14 397 Pfam PF07690 Major Facilitator Superfamily 27 306 1.4E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS19245 87d73ac1999bc692101e32414e3cbb14 397 Gene3D G3DSA:1.20.1250.20 203 394 4.4E-14 T 29-03-2018 A616_RS23905 cea0d97d4a00930ba7878f2e2ea4a6d6 696 Pfam PF02554 Carbon starvation protein CstA 33 409 8.2E-167 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A616_RS23905 cea0d97d4a00930ba7878f2e2ea4a6d6 696 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 464 592 4.4E-33 T 29-03-2018 IPR025299 CstA, C-terminal domain A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 SUPERFAMILY SSF52540 1 240 2.05E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 Gene3D G3DSA:3.40.50.300 1 258 2.7E-80 T 29-03-2018 A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 Gene3D G3DSA:3.30.70.260 259 337 1.6E-20 T 29-03-2018 A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 SMART SM00930 262 337 1.3E-20 T 29-03-2018 IPR018449 NIL domain A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 Pfam PF09383 NIL domain 264 336 8.6E-20 T 29-03-2018 IPR018449 NIL domain A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 SUPERFAMILY SSF55021 251 337 4.92E-19 T 29-03-2018 A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 SMART SM00382 30 217 8.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 Pfam PF00005 ABC transporter 21 169 2.6E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02690 ae6c53343f1e11fff44486f34a95b96f 337 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29870 6e9570a12bf4e969042a8e8a89daef9c 382 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 15 382 46.894 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29870 6e9570a12bf4e969042a8e8a89daef9c 382 SUPERFAMILY SSF56762 32 381 3.66E-123 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29870 6e9570a12bf4e969042a8e8a89daef9c 382 Gene3D G3DSA:1.10.645.10 18 221 5.2E-53 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29870 6e9570a12bf4e969042a8e8a89daef9c 382 Gene3D G3DSA:1.10.645.10 222 377 1.2E-36 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29870 6e9570a12bf4e969042a8e8a89daef9c 382 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 136 309 7.1E-69 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29870 6e9570a12bf4e969042a8e8a89daef9c 382 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 308 381 1.0E-25 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 193 4.0E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 Gene3D G3DSA:3.40.50.1000 91 259 4.8E-26 T 29-03-2018 IPR023214 HAD-like domain A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 199 1.6E-11 T 29-03-2018 IPR023214 HAD-like domain A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 1 251 3.2E-106 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 264 123.262 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 SUPERFAMILY SSF56784 1 253 1.07E-60 T 29-03-2018 IPR023214 HAD-like domain A616_RS24690 a299d1fef248d4ed347e5c6e0dc83bf4 264 Gene3D G3DSA:1.10.150.240 19 90 2.5E-34 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 56 72 2.2E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 97 115 2.2E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 78 94 2.2E-7 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 Pfam PF13458 Periplasmic binding protein 57 403 4.7E-50 T 29-03-2018 IPR028081 Leucine-binding protein domain A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 Gene3D G3DSA:3.40.50.2300 49 177 3.0E-22 T 29-03-2018 A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 SUPERFAMILY SSF53822 54 407 1.04E-78 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS29105 06151946b64f1d1fb30a046a7163714e 411 Gene3D G3DSA:3.40.50.2300 178 325 5.4E-33 T 29-03-2018 A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 322 5.3E-73 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 Gene3D G3DSA:3.90.120.10 212 309 1.9E-14 T 29-03-2018 A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 SUPERFAMILY SSF53335 1 322 8.47E-84 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 144 157 5.9E-8 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 96 110 5.9E-8 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 320 3.8E-66 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 Gene3D G3DSA:3.40.50.150 1 192 2.5E-59 T 29-03-2018 A616_RS06925 bd6839c4d62eee125ba71b78fee62043 376 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 57 69 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 A616_RS03500 8142c671353bd7e5cdab5fe6188a87ce 315 Gene3D G3DSA:1.10.10.10 1 63 1.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03500 8142c671353bd7e5cdab5fe6188a87ce 315 Pfam PF08279 HTH domain 6 58 7.8E-13 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS03500 8142c671353bd7e5cdab5fe6188a87ce 315 Pfam PF13280 WYL domain 141 311 6.3E-37 T 29-03-2018 IPR026881 WYL domain A616_RS03500 8142c671353bd7e5cdab5fe6188a87ce 315 PIRSF PIRSF016838 65 315 1.6E-22 T 29-03-2018 IPR028349 Protein PafC A616_RS03500 8142c671353bd7e5cdab5fe6188a87ce 315 PIRSF PIRSF016838 1 57 0.024 T 29-03-2018 IPR028349 Protein PafC A616_RS03500 8142c671353bd7e5cdab5fe6188a87ce 315 SUPERFAMILY SSF46785 1 61 8.17E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 Gene3D G3DSA:3.40.50.720 7 149 2.5E-39 T 29-03-2018 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 46.651 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 2.1E-42 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 SUPERFAMILY SSF51735 7 147 1.69E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 2.2E-27 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 PIRSF PIRSF000102 2 312 8.1E-104 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 3.3E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 3.3E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 3.3E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 3.3E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 3.3E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 310 2.0E-155 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 Gene3D G3DSA:3.90.110.10 150 312 1.1E-47 T 29-03-2018 A616_RS30700 2765cf1d68d66be030af034d1f45a219 313 SUPERFAMILY SSF56327 151 309 5.62E-52 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A616_RS10020 1b836426543b60496ad37929fcab84ce 129 SMART SM00232 2 124 5.9E-4 T 29-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A616_RS10020 1b836426543b60496ad37929fcab84ce 129 Gene3D G3DSA:3.40.140.10 1 123 9.0E-20 T 29-03-2018 A616_RS10020 1b836426543b60496ad37929fcab84ce 129 Pfam PF14464 Prokaryotic homologs of the JAB domain 4 103 8.4E-22 T 29-03-2018 IPR028090 JAB domain, prokaryotic A616_RS10020 1b836426543b60496ad37929fcab84ce 129 SUPERFAMILY SSF102712 1 119 1.31E-27 T 29-03-2018 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 SUPERFAMILY SSF51569 2 290 2.38E-98 T 29-03-2018 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 Gene3D G3DSA:3.20.20.70 1 331 2.0E-110 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 496 1.2E-213 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 508 42.94 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 SMART SM00917 368 499 6.5E-38 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 498 3.4E-35 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 SUPERFAMILY SSF110921 411 498 1.7E-19 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS09490 a0cda2a74771a171db96924457dd997c 512 Pfam PF00682 HMGL-like 4 272 1.9E-99 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 SUPERFAMILY SSF52025 409 499 2.09E-18 T 29-03-2018 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 PRINTS PR00723 Subtilisin serine protease family (S8) signature 598 614 3.5E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 PRINTS PR00723 Subtilisin serine protease family (S8) signature 248 261 3.5E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 PRINTS PR00723 Subtilisin serine protease family (S8) signature 194 213 3.5E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 199 210 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 Pfam PF05922 Peptidase inhibitor I9 71 159 2.1E-6 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 SUPERFAMILY SSF52743 542 667 1.48E-75 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 SUPERFAMILY SSF52743 90 377 1.48E-75 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 Pfam PF00082 Subtilase family 194 653 1.6E-59 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 252 262 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 Gene3D G3DSA:2.60.40.1710 688 808 4.9E-10 T 29-03-2018 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 Gene3D G3DSA:3.40.50.200 148 667 2.6E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 Pfam PF02225 PA domain 419 480 3.5E-12 T 29-03-2018 IPR003137 PA domain A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 Gene3D G3DSA:3.30.70.80 60 147 1.4E-8 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A616_RS31965 29020e9617c27517091b4a7a88f898e9 1037 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 599 609 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A616_RS23110 a725902ba982ea5e6709a0991a84447a 272 Gene3D G3DSA:3.20.20.70 7 208 2.7E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS23110 a725902ba982ea5e6709a0991a84447a 272 SUPERFAMILY SSF102114 27 200 3.53E-11 T 29-03-2018 A616_RS23110 a725902ba982ea5e6709a0991a84447a 272 Pfam PF04055 Radical SAM superfamily 29 192 1.6E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS23110 a725902ba982ea5e6709a0991a84447a 272 SMART SM00729 24 244 0.006 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS05950 c35af679c494fe132090ee78f6eb22d1 203 PIRSF PIRSF037778 10 202 2.8E-46 T 29-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 A616_RS05950 c35af679c494fe132090ee78f6eb22d1 203 Pfam PF12822 ECF transporter, substrate-specific component 15 190 9.9E-26 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 A616_RS08900 5eb15fbc1bcf891d1c53db8fe9ef4b36 339 PIRSF PIRSF029120 1 325 7.0E-66 T 29-03-2018 IPR011226 ATP-grasp family A616_RS08900 5eb15fbc1bcf891d1c53db8fe9ef4b36 339 Gene3D G3DSA:3.40.50.20 8 114 4.8E-7 T 29-03-2018 A616_RS08900 5eb15fbc1bcf891d1c53db8fe9ef4b36 339 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 281 288 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS08900 5eb15fbc1bcf891d1c53db8fe9ef4b36 339 Gene3D G3DSA:3.30.470.20 115 332 2.9E-19 T 29-03-2018 A616_RS08900 5eb15fbc1bcf891d1c53db8fe9ef4b36 339 SUPERFAMILY SSF56059 112 317 1.13E-21 T 29-03-2018 A616_RS08900 5eb15fbc1bcf891d1c53db8fe9ef4b36 339 Pfam PF15632 ATP-grasp in the biosynthetic pathway with Ter operon 4 333 3.1E-111 T 29-03-2018 IPR011226 ATP-grasp family A616_RS29215 5354d2ca004b8d6c7edc219313674a25 204 Gene3D G3DSA:3.40.50.880 1 204 1.0E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS29215 5354d2ca004b8d6c7edc219313674a25 204 PIRSF PIRSF000495 1 201 8.6E-74 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A616_RS29215 5354d2ca004b8d6c7edc219313674a25 204 Pfam PF00117 Glutamine amidotransferase class-I 4 198 1.0E-25 T 29-03-2018 IPR017926 Glutamine amidotransferase A616_RS29215 5354d2ca004b8d6c7edc219313674a25 204 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 196 2.7E-75 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A616_RS29215 5354d2ca004b8d6c7edc219313674a25 204 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 198 36.983 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A616_RS29215 5354d2ca004b8d6c7edc219313674a25 204 SUPERFAMILY SSF52317 2 198 1.86E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 Gene3D G3DSA:3.40.50.300 256 495 3.4E-37 T 29-03-2018 A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 Gene3D G3DSA:3.40.50.300 3 255 1.5E-51 T 29-03-2018 A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 SUPERFAMILY SSF52540 7 223 8.05E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 Pfam PF00005 ABC transporter 24 172 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 Pfam PF00005 ABC transporter 276 432 1.8E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 SUPERFAMILY SSF52540 246 487 2.52E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS19690 54e9a41dae4bfdff489390657c0ce611 513 SMART SM00382 32 228 3.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 Pfam PF01593 Flavin containing amine oxidoreductase 37 483 2.4E-69 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 Gene3D G3DSA:1.10.405.10 132 228 9.1E-24 T 29-03-2018 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 SUPERFAMILY SSF54373 324 433 1.05E-29 T 29-03-2018 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 SUPERFAMILY SSF51905 445 483 8.63E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 SUPERFAMILY SSF51905 27 343 8.63E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 Gene3D G3DSA:3.90.660.10 229 437 6.8E-38 T 29-03-2018 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 Gene3D G3DSA:3.90.660.10 51 131 9.2E-21 T 29-03-2018 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 PRINTS PR00757 Flavin-containing amine oxidase signature 434 456 1.6E-7 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 PRINTS PR00757 Flavin-containing amine oxidase signature 465 482 1.6E-7 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A616_RS21955 5ce16f72fbaae2ba3f17a726c925d50b 486 PRINTS PR00757 Flavin-containing amine oxidase signature 29 48 1.6E-7 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 Hamap MF_00551 Uridine kinase [udk]. 1 205 42.111 T 29-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 TIGRFAM TIGR00235 udk: uridine kinase 5 204 5.8E-89 T 29-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 SUPERFAMILY SSF52540 3 197 5.77E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 PRINTS PR00988 Uridine kinase signature 4 21 1.4E-38 T 29-03-2018 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 PRINTS PR00988 Uridine kinase signature 34 45 1.4E-38 T 29-03-2018 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 PRINTS PR00988 Uridine kinase signature 79 94 1.4E-38 T 29-03-2018 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 PRINTS PR00988 Uridine kinase signature 149 160 1.4E-38 T 29-03-2018 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 PRINTS PR00988 Uridine kinase signature 135 145 1.4E-38 T 29-03-2018 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 PRINTS PR00988 Uridine kinase signature 171 184 1.4E-38 T 29-03-2018 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 191 8.4E-48 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 A616_RS10865 35ee5729d7e40c2524ccc0cc72d03a92 214 Gene3D G3DSA:3.40.50.300 2 214 8.1E-62 T 29-03-2018 A616_RS29195 d539ff9e961e7867f1e425786f0e244f 188 Gene3D G3DSA:3.40.630.30 1 186 8.4E-32 T 29-03-2018 A616_RS29195 d539ff9e961e7867f1e425786f0e244f 188 Pfam PF13302 Acetyltransferase (GNAT) domain 8 153 1.5E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS29195 d539ff9e961e7867f1e425786f0e244f 188 SUPERFAMILY SSF55729 2 179 5.05E-40 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 127 23.451 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 127 7.4E-31 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 127 7.7E-35 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 SUPERFAMILY SSF56214 1 126 1.57E-31 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 Gene3D G3DSA:3.90.470.20 1 128 7.4E-34 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 127 2.0E-23 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A616_RS02850 5823bbee4dbfa227c6f472204cbeabdc 128 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 97 2.1E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 SUPERFAMILY SSF52172 1 163 1.3E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 139 210 3.9E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 SMART SM00862 139 210 9.1E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 Pfam PF00072 Response regulator receiver domain 3 109 1.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 SMART SM00448 1 111 4.5E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 Gene3D G3DSA:1.10.10.10 116 215 4.3E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04450 66f0ac9b3941dfaab66d56f999ecfe1f 215 Gene3D G3DSA:3.40.50.2300 1 115 3.4E-33 T 29-03-2018 A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 SUPERFAMILY SSF46785 9 138 8.14E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 Pfam PF01047 MarR family 34 85 3.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 Gene3D G3DSA:1.10.10.10 2 144 5.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.2E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.2E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.2E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31870 8bc03425dfea27c6f8c75fd80d4b1c99 147 SMART SM00347 27 124 5.6E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS11325 5f2f8208ae7f0bd3bc06410c85140321 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 76 3.6E-18 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS11325 5f2f8208ae7f0bd3bc06410c85140321 301 SUPERFAMILY SSF161098 94 284 2.35E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS11325 5f2f8208ae7f0bd3bc06410c85140321 301 Gene3D G3DSA:1.10.3720.10 28 289 2.9E-49 T 29-03-2018 A616_RS11325 5f2f8208ae7f0bd3bc06410c85140321 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 300 1.1E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS16015 002da5898994345590f70c3bcb64a38b 547 Gene3D G3DSA:3.90.76.10 70 178 1.0E-26 T 29-03-2018 A616_RS16015 002da5898994345590f70c3bcb64a38b 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 462 3.9E-85 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS16015 002da5898994345590f70c3bcb64a38b 547 Gene3D G3DSA:3.40.190.10 179 317 1.3E-31 T 29-03-2018 A616_RS16015 002da5898994345590f70c3bcb64a38b 547 SUPERFAMILY SSF53850 49 547 1.61E-128 T 29-03-2018 A616_RS16015 002da5898994345590f70c3bcb64a38b 547 PIRSF PIRSF002741 8 547 8.3E-102 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS16015 002da5898994345590f70c3bcb64a38b 547 Gene3D G3DSA:3.10.105.10 318 519 6.9E-52 T 29-03-2018 A616_RS11190 e5f9891ebf3d2db96cb258cafd89138d 148 Pfam PF00583 Acetyltransferase (GNAT) family 38 128 1.7E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS11190 e5f9891ebf3d2db96cb258cafd89138d 148 SUPERFAMILY SSF55729 3 135 4.53E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11190 e5f9891ebf3d2db96cb258cafd89138d 148 Gene3D G3DSA:1.10.287.900 2 39 1.0E-15 T 29-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 A616_RS11190 e5f9891ebf3d2db96cb258cafd89138d 148 Gene3D G3DSA:3.40.630.30 43 141 1.2E-15 T 29-03-2018 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Gene3D G3DSA:3.30.310.50 386 474 2.4E-18 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Gene3D G3DSA:3.40.120.10 276 385 1.6E-32 T 29-03-2018 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 245 260 1.3E-16 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 183 202 1.3E-16 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 217 230 1.3E-16 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 1.3E-16 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 SUPERFAMILY SSF53738 3 190 2.35E-44 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 136 1.2E-40 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 SUPERFAMILY SSF55957 374 471 1.31E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 263 2.8E-23 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Gene3D G3DSA:3.40.120.10 173 275 1.1E-26 T 29-03-2018 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Gene3D G3DSA:3.40.120.10 1 172 2.8E-45 T 29-03-2018 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 270 381 1.7E-29 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 417 467 2.4E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 SUPERFAMILY SSF53738 253 388 6.67E-34 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS21060 a93a1b72f3a11c5d544d74924bab8283 474 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A616_RS01225 4c52a0a1c1960e4d9036400ac2cf5edd 357 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 37.763 T 29-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 A616_RS01225 4c52a0a1c1960e4d9036400ac2cf5edd 357 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 54 253 3.3E-72 T 29-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 A616_RS01225 4c52a0a1c1960e4d9036400ac2cf5edd 357 SUPERFAMILY SSF55931 4 269 6.17E-85 T 29-03-2018 A616_RS01225 4c52a0a1c1960e4d9036400ac2cf5edd 357 Gene3D G3DSA:3.30.590.10 3 256 3.5E-84 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A616_RS01225 4c52a0a1c1960e4d9036400ac2cf5edd 357 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 29-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 A616_RS25055 c8ea276a1ec0c80471b9dd947964555e 394 Gene3D G3DSA:3.40.50.300 1 308 6.1E-58 T 29-03-2018 A616_RS25055 c8ea276a1ec0c80471b9dd947964555e 394 SUPERFAMILY SSF52540 1 293 4.05E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25055 c8ea276a1ec0c80471b9dd947964555e 394 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 6 300 6.1E-81 T 29-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A616_RS25055 c8ea276a1ec0c80471b9dd947964555e 394 Pfam PF02374 Anion-transporting ATPase 1 301 4.2E-94 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A616_RS00760 fa95dd88cdae834aa63271357033096a 123 Pfam PF00575 S1 RNA binding domain 3 72 1.6E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS00760 fa95dd88cdae834aa63271357033096a 123 SMART SM00316 4 73 2.8E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS00760 fa95dd88cdae834aa63271357033096a 123 SUPERFAMILY SSF50249 4 85 1.24E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS00760 fa95dd88cdae834aa63271357033096a 123 Gene3D G3DSA:2.40.50.140 1 79 1.4E-25 T 29-03-2018 A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 Gene3D G3DSA:3.40.50.620 1 139 1.5E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 PRINTS PR01438 Universal stress protein signature 146 164 1.3E-17 T 29-03-2018 IPR006015 Universal stress protein A A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 PRINTS PR01438 Universal stress protein signature 263 285 1.3E-17 T 29-03-2018 IPR006015 Universal stress protein A A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 PRINTS PR01438 Universal stress protein signature 245 257 1.3E-17 T 29-03-2018 IPR006015 Universal stress protein A A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 SUPERFAMILY SSF52402 1 140 2.51E-28 T 29-03-2018 A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 Gene3D G3DSA:3.40.50.620 140 285 3.6E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 Pfam PF00582 Universal stress protein family 2 137 4.3E-24 T 29-03-2018 IPR006016 UspA GO:0006950 A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 Pfam PF00582 Universal stress protein family 146 285 5.2E-29 T 29-03-2018 IPR006016 UspA GO:0006950 A616_RS24810 72b1f72bf707d9bfb4b949e44af7c773 285 SUPERFAMILY SSF52402 146 285 8.2E-33 T 29-03-2018 A616_RS09250 e861fe951e7a69c41f8fdfdb6a6de327 124 SUPERFAMILY SSF54427 2 112 3.17E-14 T 29-03-2018 IPR032710 NTF2-like domain A616_RS09250 e861fe951e7a69c41f8fdfdb6a6de327 124 Gene3D G3DSA:3.10.450.50 2 124 2.5E-13 T 29-03-2018 A616_RS09250 e861fe951e7a69c41f8fdfdb6a6de327 124 Pfam PF12680 SnoaL-like domain 12 105 1.7E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.10 10 54 0.2 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 218 286 1.3E-16 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 381 451 2.9E-12 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 535 614 3.3E-17 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 456 531 1.73E-12 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 124 206 1.1E-13 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 287 370 1.2E-14 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 218 279 8.89E-13 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 539 613 8.44E-13 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 452 534 5.2E-14 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 133 204 1.73E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 297 364 3.06E-11 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 49 125 3.92E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 291 367 0.22 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 370 449 0.0048 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 211 286 4.3E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 535 612 1.4E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 453 530 0.047 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 124 203 1.5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SMART SM00635 48 122 3.4 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Gene3D G3DSA:2.60.40.1080 55 123 5.6E-12 T 29-03-2018 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 SUPERFAMILY SSF49373 378 449 3.66E-10 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Pfam PF02368 Bacterial Ig-like domain (group 2) 400 437 2.1E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Pfam PF02368 Bacterial Ig-like domain (group 2) 487 522 1.5E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Pfam PF02368 Bacterial Ig-like domain (group 2) 242 274 4.4E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS20185 d07e61f6c0e077ff74d64cf28d8aa88b 614 Pfam PF02368 Bacterial Ig-like domain (group 2) 544 601 6.9E-9 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 Pfam PF00005 ABC transporter 25 183 6.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 6.6E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 SUPERFAMILY SSF52540 4 254 1.69E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 Gene3D G3DSA:3.40.50.300 1 327 5.4E-81 T 29-03-2018 A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 1.2E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS25615 4c346b11db31d3f74555950efb095d5d 328 SMART SM00382 33 233 1.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15690 94d24222831a5afa26c4f7cdf22b8a78 242 Gene3D G3DSA:3.40.50.1820 3 232 6.6E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15690 94d24222831a5afa26c4f7cdf22b8a78 242 SUPERFAMILY SSF53474 3 230 3.21E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15690 94d24222831a5afa26c4f7cdf22b8a78 242 Pfam PF00975 Thioesterase domain 2 228 1.3E-39 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A616_RS31455 a33cd41a29b468e992b6d7af343e6911 484 SUPERFAMILY SSF88713 65 255 4.45E-31 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS31455 a33cd41a29b468e992b6d7af343e6911 484 Gene3D G3DSA:3.20.20.370 32 264 2.2E-33 T 29-03-2018 A616_RS31455 a33cd41a29b468e992b6d7af343e6911 484 Gene3D G3DSA:3.20.20.370 268 484 3.4E-51 T 29-03-2018 A616_RS31455 a33cd41a29b468e992b6d7af343e6911 484 Pfam PF01522 Polysaccharide deacetylase 68 185 3.9E-22 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS31455 a33cd41a29b468e992b6d7af343e6911 484 Pfam PF01522 Polysaccharide deacetylase 290 412 1.2E-28 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS31455 a33cd41a29b468e992b6d7af343e6911 484 SUPERFAMILY SSF88713 281 483 2.02E-52 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS11280 91f738350405e06911763661a8a5eb80 345 Gene3D G3DSA:1.20.272.10 227 345 2.3E-34 T 29-03-2018 A616_RS11280 91f738350405e06911763661a8a5eb80 345 SUPERFAMILY SSF52540 8 209 4.61E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11280 91f738350405e06911763661a8a5eb80 345 Pfam PF06144 DNA polymerase III, delta subunit 19 195 1.5E-36 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A616_RS11280 91f738350405e06911763661a8a5eb80 345 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 335 1.8E-74 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A616_RS11280 91f738350405e06911763661a8a5eb80 345 SUPERFAMILY SSF48019 218 335 2.21E-26 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A616_RS11280 91f738350405e06911763661a8a5eb80 345 Gene3D G3DSA:3.40.50.300 5 145 3.0E-28 T 29-03-2018 A616_RS11280 91f738350405e06911763661a8a5eb80 345 Gene3D G3DSA:1.10.8.60 149 226 7.0E-18 T 29-03-2018 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 11 374 8.9E-80 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 Gene3D G3DSA:3.40.630.10 1 183 4.6E-39 T 29-03-2018 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 Pfam PF01546 Peptidase family M20/M25/M40 78 381 4.0E-35 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 Pfam PF07687 Peptidase dimerisation domain 179 287 2.7E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 SUPERFAMILY SSF55031 181 285 5.23E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 Gene3D G3DSA:3.30.70.360 184 279 1.4E-21 T 29-03-2018 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 SUPERFAMILY SSF53187 3 180 1.2E-61 T 29-03-2018 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 SUPERFAMILY SSF53187 303 385 1.2E-61 T 29-03-2018 A616_RS23330 da26fb2d6c7cf727e3fe2b7c4b7a5434 386 Gene3D G3DSA:3.40.630.10 280 386 3.4E-9 T 29-03-2018 A616_RS24340 323a5e2cb59cc0c58ec549e56db762a5 367 Pfam PF03845 Spore germination protein 14 329 7.5E-77 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS24340 323a5e2cb59cc0c58ec549e56db762a5 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 14 361 1.8E-58 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26500 dce8f0369a7fb63c0190f81152bc75d1 335 Gene3D G3DSA:2.70.70.10 192 335 1.9E-27 T 29-03-2018 A616_RS26500 dce8f0369a7fb63c0190f81152bc75d1 335 Pfam PF01551 Peptidase family M23 214 311 5.1E-20 T 29-03-2018 IPR016047 Peptidase M23 A616_RS26500 dce8f0369a7fb63c0190f81152bc75d1 335 SUPERFAMILY SSF53955 37 188 3.09E-11 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS26500 dce8f0369a7fb63c0190f81152bc75d1 335 Gene3D G3DSA:1.10.530.10 27 191 6.0E-11 T 29-03-2018 A616_RS26500 dce8f0369a7fb63c0190f81152bc75d1 335 SUPERFAMILY SSF51261 151 325 5.23E-33 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 SMART SM00079 57 279 2.7E-5 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 Gene3D G3DSA:3.40.190.10 47 167 2.7E-33 T 29-03-2018 A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 SUPERFAMILY SSF53850 15 279 2.46E-71 T 29-03-2018 A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 278 3.8E-62 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 SMART SM00062 57 280 2.4E-82 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 81 94 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A616_RS07190 1858907a1c400ee22c1991ddfc72a90a 283 Gene3D G3DSA:3.40.190.10 168 283 4.9E-20 T 29-03-2018 A616_RS26850 d335b807500e993da2fef66b4ef183b8 321 Gene3D G3DSA:3.90.226.10 46 319 2.3E-43 T 29-03-2018 A616_RS26850 d335b807500e993da2fef66b4ef183b8 321 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 53 268 9.7E-71 T 29-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A616_RS26850 d335b807500e993da2fef66b4ef183b8 321 SUPERFAMILY SSF52096 198 258 3.65E-41 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS26850 d335b807500e993da2fef66b4ef183b8 321 SUPERFAMILY SSF52096 49 167 3.65E-41 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS26850 d335b807500e993da2fef66b4ef183b8 321 Pfam PF01343 Peptidase family S49 122 263 9.6E-50 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A616_RS21835 c0427d045de5b0e25ddd73e8e63e1875 310 Gene3D G3DSA:3.90.1640.10 1 188 9.9E-72 T 29-03-2018 A616_RS21835 c0427d045de5b0e25ddd73e8e63e1875 310 SMART SM01131 181 307 8.1E-53 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS21835 c0427d045de5b0e25ddd73e8e63e1875 310 Pfam PF02833 DHHA2 domain 183 305 1.8E-21 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS21835 c0427d045de5b0e25ddd73e8e63e1875 310 SUPERFAMILY SSF64182 1 306 4.19E-84 T 29-03-2018 A616_RS21835 c0427d045de5b0e25ddd73e8e63e1875 310 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 46.214 T 29-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS21835 c0427d045de5b0e25ddd73e8e63e1875 310 Pfam PF01368 DHH family 5 146 4.7E-31 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS10110 c56d30d1b6669f4358ba8ed009342f4b 411 Pfam PF00535 Glycosyl transferase family 2 10 168 3.8E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS10110 c56d30d1b6669f4358ba8ed009342f4b 411 Gene3D G3DSA:3.90.550.10 3 280 8.2E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10110 c56d30d1b6669f4358ba8ed009342f4b 411 SUPERFAMILY SSF53448 7 207 1.69E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 1.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 1.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 1.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 SMART SM00422 5 74 4.9E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 SUPERFAMILY SSF46955 6 114 1.76E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 Gene3D G3DSA:1.10.1660.10 1 59 5.3E-16 T 29-03-2018 A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 Pfam PF13411 MerR HTH family regulatory protein 6 72 9.1E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS16070 d333910e830df6a7cf5567c9651b45e5 263 Gene3D G3DSA:1.10.1660.10 60 129 7.3E-5 T 29-03-2018 A616_RS13140 dcfc141cb85970fcd17f08d932c749b3 300 SUPERFAMILY SSF48576 9 278 4.14E-84 T 29-03-2018 IPR008949 Isoprenoid synthase domain A616_RS13140 dcfc141cb85970fcd17f08d932c749b3 300 Pfam PF00348 Polyprenyl synthetase 33 274 1.6E-58 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 A616_RS13140 dcfc141cb85970fcd17f08d932c749b3 300 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 100 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site A616_RS13140 dcfc141cb85970fcd17f08d932c749b3 300 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 219 231 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site A616_RS13140 dcfc141cb85970fcd17f08d932c749b3 300 Gene3D G3DSA:1.10.600.10 3 300 1.4E-86 T 29-03-2018 IPR008949 Isoprenoid synthase domain A616_RS06600 fd352af3cbcf95495f9e915f04c615d5 248 Gene3D G3DSA:3.40.50.300 1 247 7.7E-75 T 29-03-2018 A616_RS06600 fd352af3cbcf95495f9e915f04c615d5 248 PIRSF PIRSF039085 1 248 2.3E-107 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS06600 fd352af3cbcf95495f9e915f04c615d5 248 Pfam PF00005 ABC transporter 19 172 3.0E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS06600 fd352af3cbcf95495f9e915f04c615d5 248 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS06600 fd352af3cbcf95495f9e915f04c615d5 248 SMART SM00382 28 220 2.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS06600 fd352af3cbcf95495f9e915f04c615d5 248 SUPERFAMILY SSF52540 3 242 1.54E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Pfam PF02824 TGS domain 390 449 2.2E-21 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 27 719 6.0E-251 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Gene3D G3DSA:3.30.460.10 189 327 7.2E-48 T 29-03-2018 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Pfam PF13291 ACT domain 644 719 2.4E-21 T 29-03-2018 IPR002912 ACT domain A616_RS10735 f738d415e5826bf40bc87aed10997216 723 SUPERFAMILY SSF55021 645 721 1.96E-14 T 29-03-2018 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Gene3D G3DSA:3.10.20.30 384 457 1.6E-23 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS10735 f738d415e5826bf40bc87aed10997216 723 SMART SM00471 42 154 2.5E-8 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS10735 f738d415e5826bf40bc87aed10997216 723 SUPERFAMILY SSF81271 377 449 1.96E-22 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 SUPERFAMILY SSF81301 193 365 7.52E-66 T 29-03-2018 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 SMART SM00954 236 346 9.9E-69 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 SUPERFAMILY SSF109604 5 192 1.66E-75 T 29-03-2018 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Pfam PF13328 HD domain 27 176 1.3E-52 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Gene3D G3DSA:3.30.70.260 642 723 1.9E-13 T 29-03-2018 A616_RS10735 f738d415e5826bf40bc87aed10997216 723 Pfam PF04607 Region found in RelA / SpoT proteins 236 346 2.9E-40 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 A616_RS03655 70785b29702106051d118c9335fb55f0 235 SMART SM00382 28 230 9.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03655 70785b29702106051d118c9335fb55f0 235 Pfam PF00005 ABC transporter 19 164 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS03655 70785b29702106051d118c9335fb55f0 235 PIRSF PIRSF039137 1 235 1.2E-108 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 A616_RS03655 70785b29702106051d118c9335fb55f0 235 Gene3D G3DSA:3.40.50.300 1 235 4.3E-56 T 29-03-2018 A616_RS03655 70785b29702106051d118c9335fb55f0 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS03655 70785b29702106051d118c9335fb55f0 235 SUPERFAMILY SSF52540 3 233 5.0E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10340 c541580289442cb709677a024d39f6cc 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 224 292 9.2E-23 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 SUPERFAMILY SSF54782 218 306 3.27E-25 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 Gene3D G3DSA:3.40.190.10 1 104 1.3E-41 T 29-03-2018 A616_RS10340 c541580289442cb709677a024d39f6cc 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 PIRSF PIRSF001438 1 309 6.5E-124 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 1.5E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 1.5E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 1.5E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 1.5E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 1.5E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 Gene3D G3DSA:3.30.160.40 219 303 4.7E-26 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 Gene3D G3DSA:3.40.190.10 105 197 7.6E-38 T 29-03-2018 A616_RS10340 c541580289442cb709677a024d39f6cc 309 SUPERFAMILY SSF53850 3 215 3.58E-83 T 29-03-2018 A616_RS10340 c541580289442cb709677a024d39f6cc 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 294 9.1E-114 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 294 40.347 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS10340 c541580289442cb709677a024d39f6cc 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 210 4.0E-80 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 245 4.1E-70 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 Pfam PF11967 Recombination protein O N terminal 1 80 4.2E-20 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 Hamap MF_00201 DNA repair protein RecO [recO]. 1 245 30.496 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 SUPERFAMILY SSF50249 1 80 1.56E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 SUPERFAMILY SSF57863 83 234 3.14E-44 T 29-03-2018 A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 Pfam PF02565 Recombination protein O C terminal 84 239 2.5E-42 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A616_RS11660 7beb14e417fd5de995f3fe9e612578bf 257 Gene3D G3DSA:2.40.50.140 1 83 1.9E-20 T 29-03-2018 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 7 677 5.2E-275 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PIRSF PIRSF005419 3 680 2.7E-261 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 Pfam PF00771 FHIPEP family 17 669 3.3E-276 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 128 151 - T 29-03-2018 IPR025505 FHIPEP conserved site A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 61 80 1.1E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 172 189 1.1E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 160 1.1E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 123 139 1.1E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 24 37 1.1E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS19945 8a198d5fa2ba800ee1b9c9996c683c92 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 223 237 1.1E-55 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Gene3D G3DSA:3.30.450.20 238 378 1.2E-15 T 29-03-2018 A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 SUPERFAMILY SSF55785 250 369 6.98E-15 T 29-03-2018 IPR000014 PAS domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Pfam PF03707 Bacterial signalling protein N terminal repeat 55 110 5.0E-17 T 29-03-2018 IPR005330 MHYT domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 166 2.1E-13 T 29-03-2018 IPR005330 MHYT domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Pfam PF03707 Bacterial signalling protein N terminal repeat 184 230 1.1E-6 T 29-03-2018 IPR005330 MHYT domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Gene3D G3DSA:3.20.20.450 548 811 1.5E-101 T 29-03-2018 IPR001633 EAL domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 SUPERFAMILY SSF141868 559 804 1.96E-92 T 29-03-2018 IPR001633 EAL domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Pfam PF13426 PAS domain 268 370 7.6E-6 T 29-03-2018 IPR000014 PAS domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 252 377 2.2E-15 T 29-03-2018 IPR000014 PAS domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 380 540 1.2E-38 T 29-03-2018 IPR000160 GGDEF domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 SUPERFAMILY SSF55073 387 546 7.06E-46 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Pfam PF00563 EAL domain 560 794 7.8E-76 T 29-03-2018 IPR001633 EAL domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Gene3D G3DSA:3.30.70.270 379 547 8.5E-55 T 29-03-2018 A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 SMART SM00052 554 799 1.5E-121 T 29-03-2018 IPR001633 EAL domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 Pfam PF00990 Diguanylate cyclase, GGDEF domain 382 539 1.0E-47 T 29-03-2018 IPR000160 GGDEF domain A616_RS12750 48cd217bcb9a620ceb9d93df25c08857 816 SMART SM00267 371 544 2.4E-60 T 29-03-2018 IPR000160 GGDEF domain A616_RS12410 85761de930980682136342acda8e8ca2 190 Gene3D G3DSA:1.10.10.10 111 188 2.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12410 85761de930980682136342acda8e8ca2 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 179 3.7E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12410 85761de930980682136342acda8e8ca2 190 Pfam PF08281 Sigma-70, region 4 127 177 5.4E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12410 85761de930980682136342acda8e8ca2 190 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12410 85761de930980682136342acda8e8ca2 190 SUPERFAMILY SSF88946 17 102 9.02E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12410 85761de930980682136342acda8e8ca2 190 SUPERFAMILY SSF88659 130 184 3.92E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12410 85761de930980682136342acda8e8ca2 190 Pfam PF04542 Sigma-70 region 2 25 89 3.2E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12410 85761de930980682136342acda8e8ca2 190 Gene3D G3DSA:1.10.1740.10 10 94 1.4E-19 T 29-03-2018 A616_RS16000 a8b8c3c048d26a4e1e0b9e33ac3f0b85 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS16000 a8b8c3c048d26a4e1e0b9e33ac3f0b85 256 SUPERFAMILY SSF52096 7 253 7.09E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS16000 a8b8c3c048d26a4e1e0b9e33ac3f0b85 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 253 4.2E-54 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS16000 a8b8c3c048d26a4e1e0b9e33ac3f0b85 256 Gene3D G3DSA:3.90.226.10 1 255 6.3E-72 T 29-03-2018 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 Pfam PF00248 Aldo/keto reductase family 30 260 6.0E-51 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PRINTS PR00069 Aldo-keto reductase signature 195 219 3.3E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PRINTS PR00069 Aldo-keto reductase signature 39 63 3.3E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 3.3E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 3.3E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PRINTS PR00069 Aldo-keto reductase signature 95 113 3.3E-49 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PIRSF PIRSF000097 3 120 3.2E-38 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 PIRSF PIRSF000097 115 271 5.9E-50 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 Gene3D G3DSA:3.20.20.100 2 273 1.7E-96 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS23190 6b877ae20bae5f5a147e6bc5f74307cd 274 SUPERFAMILY SSF51430 10 268 3.14E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS15085 ccd87300d3909669bed98321a079e58f 144 SUPERFAMILY SSF54593 7 132 1.34E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15085 ccd87300d3909669bed98321a079e58f 144 Gene3D G3DSA:3.10.180.10 1 133 7.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15085 ccd87300d3909669bed98321a079e58f 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 126 1.6E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 SMART SM00382 41 234 7.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 9.6E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 Gene3D G3DSA:3.40.50.300 3 334 2.5E-81 T 29-03-2018 A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 SUPERFAMILY SSF52540 7 255 4.51E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 8.3E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS22820 1256a89d16c73c0db7ee2623c0bf1868 335 Pfam PF00005 ABC transporter 33 184 2.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 SUPERFAMILY SSF100934 477 576 1.09E-14 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Gene3D G3DSA:3.30.420.40 1 172 3.0E-72 T 29-03-2018 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 SUPERFAMILY SSF53067 1 158 4.46E-63 T 29-03-2018 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 SUPERFAMILY SSF53067 160 352 9.88E-67 T 29-03-2018 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 113 133 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.4E-81 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 604 37.276 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 2.2E-285 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Pfam PF00012 Hsp70 protein 80 573 7.0E-222 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Pfam PF00012 Hsp70 protein 4 78 4.3E-33 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Gene3D G3DSA:3.30.420.40 173 336 1.0E-49 T 29-03-2018 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Gene3D G3DSA:1.20.1270.10 502 588 7.4E-21 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 SUPERFAMILY SSF100920 354 510 1.22E-62 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 Gene3D G3DSA:2.60.34.10 360 501 1.1E-66 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A616_RS11470 ee2a3ce91658674535f1cd293f9d5bd2 608 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A616_RS03550 0af2a97ff7ee6aa5c200fb0c14b85c41 82 SUPERFAMILY SSF82697 2 79 2.79E-30 T 29-03-2018 A616_RS03550 0af2a97ff7ee6aa5c200fb0c14b85c41 82 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 81 4.0E-22 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03550 0af2a97ff7ee6aa5c200fb0c14b85c41 82 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 79 6.1E-34 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03550 0af2a97ff7ee6aa5c200fb0c14b85c41 82 Gene3D G3DSA:3.30.1280.10 1 80 1.5E-32 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03550 0af2a97ff7ee6aa5c200fb0c14b85c41 82 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 4.6E-33 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03550 0af2a97ff7ee6aa5c200fb0c14b85c41 82 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 22.976 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS25985 b7aaa23122ff96db9803cb88d13e0f81 410 Gene3D G3DSA:1.20.1250.20 201 410 7.3E-31 T 29-03-2018 A616_RS25985 b7aaa23122ff96db9803cb88d13e0f81 410 SUPERFAMILY SSF103473 4 395 1.96E-86 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS25985 b7aaa23122ff96db9803cb88d13e0f81 410 Gene3D G3DSA:1.20.1250.20 1 200 6.4E-43 T 29-03-2018 A616_RS25985 b7aaa23122ff96db9803cb88d13e0f81 410 PIRSF PIRSF002808 3 409 8.4E-34 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 A616_RS25985 b7aaa23122ff96db9803cb88d13e0f81 410 Pfam PF07690 Major Facilitator Superfamily 15 358 6.9E-61 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS02540 22aa32e48289124c4c3124e8dde04d50 200 Gene3D G3DSA:1.10.357.10 70 200 8.9E-10 T 29-03-2018 A616_RS02540 22aa32e48289124c4c3124e8dde04d50 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 61 3.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS02540 22aa32e48289124c4c3124e8dde04d50 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS02540 22aa32e48289124c4c3124e8dde04d50 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS02540 22aa32e48289124c4c3124e8dde04d50 200 SUPERFAMILY SSF46689 12 68 2.22E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02540 22aa32e48289124c4c3124e8dde04d50 200 Gene3D G3DSA:1.10.10.60 7 69 1.2E-15 T 29-03-2018 A616_RS20505 846b5fd9df8fffe463574583d61354f8 168 Gene3D G3DSA:1.10.287.370 35 124 1.3E-7 T 29-03-2018 A616_RS20505 846b5fd9df8fffe463574583d61354f8 168 Gene3D G3DSA:1.20.5.340 128 167 0.12 T 29-03-2018 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Gene3D G3DSA:1.10.420.10 593 702 5.9E-37 T 29-03-2018 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Gene3D G3DSA:1.10.420.10 231 397 1.7E-42 T 29-03-2018 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Gene3D G3DSA:1.10.520.10 438 592 1.7E-34 T 29-03-2018 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00458 Haem peroxidase superfamily signature 93 107 5.3E-20 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00458 Haem peroxidase superfamily signature 257 272 5.3E-20 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00458 Haem peroxidase superfamily signature 171 183 5.3E-20 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00458 Haem peroxidase superfamily signature 316 331 5.3E-20 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00458 Haem peroxidase superfamily signature 153 170 5.3E-20 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 SUPERFAMILY SSF48113 435 726 9.14E-112 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 ProSitePatterns PS00436 Peroxidases active site signature. 93 104 - T 29-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Gene3D G3DSA:1.10.520.10 59 218 9.4E-40 T 29-03-2018 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 20 727 0.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 257 267 - T 29-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Pfam PF00141 Peroxidase 84 395 6.1E-52 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Pfam PF00141 Peroxidase 402 701 3.7E-40 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 29 51 2.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 70 95 2.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 479 505 2.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 55 68 2.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 265 288 2.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 SUPERFAMILY SSF48113 22 429 1.47E-160 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A616_RS16085 3fa0ab114a32613afc45cb27e0d51362 729 Hamap MF_01961 Catalase-peroxidase [katG]. 7 727 42.16 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 Gene3D G3DSA:3.30.559.10 199 440 1.6E-85 T 29-03-2018 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 Pfam PF02817 e3 binding domain 127 160 8.1E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 SUPERFAMILY SSF52777 207 437 6.23E-85 T 29-03-2018 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 215 438 3.2E-81 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 Pfam PF00364 Biotin-requiring enzyme 4 76 1.4E-23 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 Gene3D G3DSA:4.10.320.10 120 180 2.6E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 Gene3D G3DSA:2.40.50.100 5 79 5.1E-19 T 29-03-2018 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 SUPERFAMILY SSF51230 1 94 3.01E-28 T 29-03-2018 IPR011053 Single hybrid motif A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A616_RS13285 2c4916d61f9809fabdaf47f61b48ccf9 445 SUPERFAMILY SSF47005 121 164 2.22E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 SUPERFAMILY SSF52172 13 190 2.33E-38 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 Pfam PF00072 Response regulator receiver domain 14 122 9.2E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 SMART SM00448 12 122 3.0E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 SMART SM00862 161 237 7.9E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 237 1.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 Gene3D G3DSA:1.10.10.10 130 240 9.6E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08480 7ddc92e868d2315d837c2f61ca76e801 240 Gene3D G3DSA:3.40.50.2300 6 129 4.5E-33 T 29-03-2018 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Gene3D G3DSA:3.40.50.720 320 430 2.9E-25 T 29-03-2018 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 17 422 1.1E-130 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 SUPERFAMILY SSF48179 213 310 2.55E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 214 304 4.4E-31 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 17 193 7.7E-41 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 SUPERFAMILY SSF52413 322 426 2.75E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Gene3D G3DSA:1.20.5.170 213 233 4.8E-14 T 29-03-2018 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 331 425 8.5E-20 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 PIRSF PIRSF500136 6 439 3.0E-147 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Gene3D G3DSA:3.40.50.720 1 211 8.3E-36 T 29-03-2018 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 Gene3D G3DSA:1.10.1040.10 234 310 8.8E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 SMART SM00984 331 427 4.3E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 SUPERFAMILY SSF51735 17 207 2.3E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS07825 7ba63ee4c568c44ee4f48e5c2d25510b 453 PIRSF PIRSF000124 16 429 1.2E-63 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 SUPERFAMILY SSF50447 206 303 7.07E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 3.1E-230 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 8.2E-34 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 2.9E-16 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 SUPERFAMILY SSF52540 9 227 3.92E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 SUPERFAMILY SSF50465 305 395 8.06E-36 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 2.8E-61 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Gene3D G3DSA:2.40.30.10 194 300 2.6E-33 T 29-03-2018 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 1.1E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Gene3D G3DSA:3.40.50.300 1 74 2.8E-11 T 29-03-2018 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Gene3D G3DSA:3.40.50.300 75 193 3.6E-31 T 29-03-2018 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.431 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 Gene3D G3DSA:2.40.30.10 302 394 5.4E-32 T 29-03-2018 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS01375 0226ca1714919c609f5983a84bfb7d5a 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.1E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 SUPERFAMILY SSF51735 7 159 3.09E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 Gene3D G3DSA:3.40.50.720 3 142 1.2E-38 T 29-03-2018 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 328 1.1E-57 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 Gene3D G3DSA:3.30.360.10 143 325 3.6E-71 T 29-03-2018 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 119 6.6E-35 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 PIRSF PIRSF000148 6 346 6.6E-133 T 29-03-2018 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 342 38.973 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 SUPERFAMILY SSF55347 131 329 5.36E-76 T 29-03-2018 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 343 3.7E-146 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19735 04a376bb686d29861b4b652411fb03d7 346 SMART SM00859 8 123 2.5E-47 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A616_RS32185 e0ea08dedad20124512086dce6188066 95 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS32185 e0ea08dedad20124512086dce6188066 95 Gene3D G3DSA:3.30.70.60 1 95 1.4E-33 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A616_RS32185 e0ea08dedad20124512086dce6188066 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.85 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A616_RS32185 e0ea08dedad20124512086dce6188066 95 Pfam PF01250 Ribosomal protein S6 3 92 4.6E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32185 e0ea08dedad20124512086dce6188066 95 SUPERFAMILY SSF54995 1 94 3.79E-36 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32185 e0ea08dedad20124512086dce6188066 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 8.9E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS13200 a39fdb94612448e108f5a3f48c3c0e79 194 SMART SM00947 28 184 4.5E-35 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A616_RS13200 a39fdb94612448e108f5a3f48c3c0e79 194 SUPERFAMILY SSF53056 5 183 4.71E-40 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A616_RS13200 a39fdb94612448e108f5a3f48c3c0e79 194 Pfam PF00484 Carbonic anhydrase 36 179 1.1E-18 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A616_RS13200 a39fdb94612448e108f5a3f48c3c0e79 194 Gene3D G3DSA:3.40.1050.10 2 194 4.1E-35 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A616_RS04980 a6ebf4b9801f2e399ceb9be4a5fd4e27 80 SUPERFAMILY SSF47413 1 74 1.93E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS04980 a6ebf4b9801f2e399ceb9be4a5fd4e27 80 Gene3D G3DSA:1.10.260.40 3 79 7.1E-8 T 29-03-2018 A616_RS04980 a6ebf4b9801f2e399ceb9be4a5fd4e27 80 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 73 8.6E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 SMART SM00644 9 148 1.6E-25 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 Gene3D G3DSA:3.40.80.10 1 179 5.4E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 Gene3D G3DSA:3.30.457.10 252 278 0.5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 Gene3D G3DSA:3.30.457.10 210 251 8.4E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 Pfam PF07833 Copper amine oxidase N-terminal domain 207 239 1.5E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 SUPERFAMILY SSF55383 211 271 1.7E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 SUPERFAMILY SSF55846 4 174 6.15E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS28020 12f7a4d31843cddb84317bb44c751328 278 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 21 147 3.9E-20 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 Gene3D G3DSA:3.30.160.20 207 289 2.8E-31 T 29-03-2018 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 Pfam PF00472 RF-1 domain 210 319 1.6E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 SUPERFAMILY SSF75620 8 351 9.03E-135 T 29-03-2018 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 Gene3D G3DSA:1.20.58.410 1 100 1.1E-20 T 29-03-2018 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 Pfam PF03462 PCRF domain 9 202 3.0E-72 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 353 2.0E-163 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.11 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A616_RS30045 b32dd90e4984103ba7b08a6907f689f2 358 SMART SM00937 63 177 4.1E-62 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 12 354 50.169 T 29-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 Gene3D G3DSA:3.20.20.70 1 353 1.8E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 Pfam PF04055 Radical SAM superfamily 58 225 1.3E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 PIRSF PIRSF004762 1 361 1.0E-103 T 29-03-2018 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 SUPERFAMILY SSF102114 12 343 2.35E-53 T 29-03-2018 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 50 351 5.8E-107 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 SMART SM00729 47 272 0.0015 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS09405 455f68e24d62e2f97863c4f841c0158f 368 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 13 351 1.3E-146 T 29-03-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 SUPERFAMILY SSF53686 8 349 8.38E-110 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 54 67 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 320 4.5E-80 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 Gene3D G3DSA:3.40.50.1100 121 353 9.5E-59 T 29-03-2018 A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 Gene3D G3DSA:3.40.50.1100 3 120 8.9E-24 T 29-03-2018 A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 TIGRFAM TIGR00260 thrC: threonine synthase 11 327 1.9E-106 T 29-03-2018 IPR004450 Threonine synthase-like A616_RS10605 41a4bc512fd57a8a9988ced3fb2e3b7a 360 PIRSF PIRSF038945 1 353 1.2E-167 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 Gene3D G3DSA:3.90.1180.10 1 145 3.7E-64 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.577 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 PIRSF PIRSF002181 1 144 4.3E-52 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 Pfam PF00572 Ribosomal protein L13 15 139 2.1E-58 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 SUPERFAMILY SSF52161 5 143 1.57E-61 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 2.0E-64 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01565 45b9a8e838cb7247318b91056dcdffa6 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A616_RS29885 6aa5cf9a59a6c2d0282356778d7181a0 123 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 27 122 1.0E-37 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29885 6aa5cf9a59a6c2d0282356778d7181a0 123 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 123 19.161 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 A616_RS01020 8af19d079c68f48d58c1110ded18258b 450 SUPERFAMILY SSF52540 126 349 3.29E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01020 8af19d079c68f48d58c1110ded18258b 450 Gene3D G3DSA:3.30.450.90 92 194 1.5E-5 T 29-03-2018 A616_RS01020 8af19d079c68f48d58c1110ded18258b 450 Pfam PF00437 Type II/IV secretion system protein 134 371 2.2E-22 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A616_RS01020 8af19d079c68f48d58c1110ded18258b 450 Gene3D G3DSA:3.40.50.300 195 393 1.3E-5 T 29-03-2018 A616_RS04995 fee9d76af05a93670a45233607d98983 271 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site A616_RS04995 fee9d76af05a93670a45233607d98983 271 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 217 1.8E-25 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 Pfam PF00106 short chain dehydrogenase 6 190 8.9E-56 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 Gene3D G3DSA:3.40.50.720 4 153 2.4E-46 T 29-03-2018 A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.5E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.7E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 SUPERFAMILY SSF51735 2 217 6.97E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS06955 039171fbab4ac5fce79b2c1aafb6c37a 233 Gene3D G3DSA:3.40.50.720 154 219 2.4E-13 T 29-03-2018 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Gene3D G3DSA:1.10.12.10 222 256 3.6E-9 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 SUPERFAMILY SSF48498 333 446 1.03E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Gene3D G3DSA:1.10.357.10 332 447 1.1E-8 T 29-03-2018 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Gene3D G3DSA:3.90.226.10 3 221 7.5E-70 T 29-03-2018 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 SUPERFAMILY SSF52096 3 260 2.99E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 259 1.2E-58 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Gene3D G3DSA:1.10.10.60 257 293 5.5E-10 T 29-03-2018 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 SUPERFAMILY SSF46689 260 331 4.04E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Pfam PF00440 Bacterial regulatory proteins, tetR family 268 311 1.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17815 50e3c8188455a7a8442c8ae50f38135e 447 Gene3D G3DSA:1.10.260.40 294 331 2.1E-5 T 29-03-2018 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 424 1.3E-25 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 Hamap MF_01454 GTPase Obg [obg]. 1 327 47.558 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 ProSitePatterns PS00905 GTP1/OBG family signature. 211 224 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 3.1E-12 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 3.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 3.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 226 244 3.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 224 3.1E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 Pfam PF09269 Domain of unknown function (DUF1967) 356 423 2.1E-27 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 Gene3D G3DSA:2.70.210.12 1 155 2.4E-57 T 29-03-2018 IPR006169 GTP1/OBG domain A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 Pfam PF01018 GTP1/OBG 3 157 4.3E-59 T 29-03-2018 IPR006169 GTP1/OBG domain A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 Pfam PF01926 50S ribosome-binding GTPase 160 282 7.4E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 SUPERFAMILY SSF52540 160 330 6.44E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 SUPERFAMILY SSF102741 355 425 6.28E-22 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 PIRSF PIRSF002401 1 373 6.6E-139 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 Gene3D G3DSA:3.40.50.300 157 366 4.1E-32 T 29-03-2018 A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 SUPERFAMILY SSF82051 1 157 3.01E-56 T 29-03-2018 IPR006169 GTP1/OBG domain A616_RS10575 f9d89ce298d594e009fd9aff703d8ffd 425 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 325 1.4E-139 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A616_RS12480 fc058e2074e73f487c3202bcf735068f 179 SUPERFAMILY SSF55729 11 161 1.34E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS12480 fc058e2074e73f487c3202bcf735068f 179 Pfam PF13302 Acetyltransferase (GNAT) domain 18 157 1.8E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS12480 fc058e2074e73f487c3202bcf735068f 179 Gene3D G3DSA:3.40.630.30 4 165 3.8E-22 T 29-03-2018 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 279 5.3E-98 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 Gene3D G3DSA:3.10.310.10 130 268 2.1E-50 T 29-03-2018 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 SUPERFAMILY SSF54506 146 278 1.88E-52 T 29-03-2018 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 Gene3D G3DSA:3.10.310.10 1 129 2.3E-47 T 29-03-2018 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 Pfam PF01678 Diaminopimelate epimerase 159 272 1.8E-32 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 Pfam PF01678 Diaminopimelate epimerase 3 127 1.6E-32 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 SUPERFAMILY SSF54506 1 135 8.16E-40 T 29-03-2018 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 281 40.238 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS22760 9368690dd0c85cc26d5717f9d738cf50 286 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 Pfam PF00717 Peptidase S24-like 30 69 6.4E-6 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 7 178 4.9E-42 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 ProSitePatterns PS00760 Signal peptidases I lysine active site. 102 114 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 Gene3D G3DSA:2.10.109.10 20 179 1.3E-38 T 29-03-2018 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 1.0E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 145 164 1.0E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 100 112 1.0E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 Pfam PF10502 Signal peptidase, peptidase S26 97 178 9.4E-8 T 29-03-2018 IPR019533 Peptidase S26 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 SUPERFAMILY SSF51306 23 178 2.44E-42 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS23320 2b1c08ddf0c7a17129b881f126a180a8 185 ProSitePatterns PS00761 Signal peptidases I signature 3. 150 163 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A616_RS06720 3643a85fcc395a4c87ee54d6777ef8e4 482 Pfam PF00324 Amino acid permease 14 466 7.4E-143 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A616_RS06720 3643a85fcc395a4c87ee54d6777ef8e4 482 PIRSF PIRSF006060 1 475 3.2E-84 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS06720 3643a85fcc395a4c87ee54d6777ef8e4 482 ProSitePatterns PS00218 Amino acid permeases signature. 39 70 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A616_RS08475 bc747dc048783010c257dd9ccc9113ab 668 Pfam PF00144 Beta-lactamase 61 372 9.2E-62 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS08475 bc747dc048783010c257dd9ccc9113ab 668 SUPERFAMILY SSF56601 48 372 2.98E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS08475 bc747dc048783010c257dd9ccc9113ab 668 Gene3D G3DSA:3.40.710.10 44 381 2.9E-78 T 29-03-2018 A616_RS08475 bc747dc048783010c257dd9ccc9113ab 668 Pfam PF00395 S-layer homology domain 549 590 4.2E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS08475 bc747dc048783010c257dd9ccc9113ab 668 Pfam PF00395 S-layer homology domain 487 530 6.1E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82693 134 178 4.71E-10 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82693 264 318 4.71E-10 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Gene3D G3DSA:1.20.1640.10 276 498 1.6E-34 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82714 712 794 4.84E-5 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82714 180 262 1.31E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82693 40 128 4.36E-23 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Pfam PF00873 AcrB/AcrD/AcrF family 2 1010 4.2E-186 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Gene3D G3DSA:3.30.2090.10 179 262 2.2E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Gene3D G3DSA:3.30.2090.10 710 795 1.1E-5 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82866 293 483 1.57E-36 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Gene3D G3DSA:3.30.70.1430 38 139 6.3E-30 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 PRINTS PR00702 Acriflavin resistance protein family signature 352 373 4.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 4.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 PRINTS PR00702 Acriflavin resistance protein family signature 380 404 4.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 PRINTS PR00702 Acriflavin resistance protein family signature 434 457 4.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 4.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 4.4E-26 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82866 793 1016 4.71E-47 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Gene3D G3DSA:3.30.70.1430 557 660 1.1E-11 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 Gene3D G3DSA:1.20.1640.10 796 1013 1.0E-41 T 29-03-2018 A616_RS30280 b71485958368e0d1196ede880c49410b 1036 SUPERFAMILY SSF82693 555 602 3.98E-6 T 29-03-2018 A616_RS03895 43efb2b753fb4be495bce273c6c8aa5c 96 SUPERFAMILY SSF48295 3 94 2.72E-33 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A616_RS03895 43efb2b753fb4be495bce273c6c8aa5c 96 Gene3D G3DSA:1.10.1270.10 1 96 4.0E-33 T 29-03-2018 A616_RS03895 43efb2b753fb4be495bce273c6c8aa5c 96 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 3.5E-47 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD A616_RS03895 43efb2b753fb4be495bce273c6c8aa5c 96 Pfam PF01371 Trp repressor protein 10 93 1.5E-34 T 29-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 A616_RS03895 43efb2b753fb4be495bce273c6c8aa5c 96 PIRSF PIRSF012508 1 96 3.6E-46 T 29-03-2018 IPR013368 TrpR homologue YerC/YecD A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 5 329 72.824 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 329 3.9E-132 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 240 329 5.4E-38 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 188 2.9E-29 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 SUPERFAMILY SSF53901 5 330 2.68E-75 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 Gene3D G3DSA:3.40.47.10 1 162 1.1E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20295 0a4a319bbc68b3d9a39cf8a3e6853ddb 338 Gene3D G3DSA:3.40.47.10 163 336 5.7E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS29720 24b49946ab31df9b227e97bd2d80b551 377 PIRSF PIRSF000390 9 373 2.0E-121 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A616_RS29720 24b49946ab31df9b227e97bd2d80b551 377 Gene3D G3DSA:3.40.640.10 8 244 3.1E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS29720 24b49946ab31df9b227e97bd2d80b551 377 Gene3D G3DSA:3.90.1150.10 245 377 1.1E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29720 24b49946ab31df9b227e97bd2d80b551 377 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 367 3.3E-136 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A616_RS29720 24b49946ab31df9b227e97bd2d80b551 377 SUPERFAMILY SSF53383 19 371 1.5E-122 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS07640 932e6acd448789720e22a97b9f923710 528 SUPERFAMILY SSF55486 224 527 6.04E-100 T 29-03-2018 A616_RS07640 932e6acd448789720e22a97b9f923710 528 Pfam PF03413 Peptidase propeptide and YPEB domain 158 218 1.0E-9 T 29-03-2018 IPR025711 PepSY domain A616_RS07640 932e6acd448789720e22a97b9f923710 528 Gene3D G3DSA:1.10.390.10 372 528 6.8E-50 T 29-03-2018 A616_RS07640 932e6acd448789720e22a97b9f923710 528 Gene3D G3DSA:3.10.170.10 224 371 7.7E-52 T 29-03-2018 A616_RS07640 932e6acd448789720e22a97b9f923710 528 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 77 128 1.4E-15 T 29-03-2018 IPR011096 FTP domain A616_RS07640 932e6acd448789720e22a97b9f923710 528 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 225 367 4.5E-47 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 A616_RS07640 932e6acd448789720e22a97b9f923710 528 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 370 527 2.1E-59 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 A616_RS07640 932e6acd448789720e22a97b9f923710 528 Gene3D G3DSA:3.10.450.40 144 220 0.018 T 29-03-2018 A616_RS07640 932e6acd448789720e22a97b9f923710 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 379 390 5.5E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07640 932e6acd448789720e22a97b9f923710 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 358 374 5.5E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07640 932e6acd448789720e22a97b9f923710 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 322 342 5.5E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS07640 932e6acd448789720e22a97b9f923710 528 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 442 458 5.5E-29 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 Gene3D G3DSA:3.30.70.1070 90 160 2.6E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 Gene3D G3DSA:2.40.50.110 463 522 2.6E-6 T 29-03-2018 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 SUPERFAMILY SSF110997 91 160 3.79E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 306 644 4.5E-62 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 Gene3D G3DSA:2.30.30.410 414 462 0.088 T 29-03-2018 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 Gene3D G3DSA:3.30.70.1070 161 233 0.005 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 Pfam PF08486 Stage II sporulation protein 301 389 3.9E-23 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal A616_RS10670 f4fb436afd881e60c2b3ca59aecffb78 644 Pfam PF05036 Sporulation related domain 91 161 5.2E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 A616_RS07110 abbd5ec294430b03dde3372d57faea91 132 Gene3D G3DSA:1.10.10.10 9 71 2.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07110 abbd5ec294430b03dde3372d57faea91 132 Gene3D G3DSA:1.10.4040.10 74 122 9.1E-15 T 29-03-2018 A616_RS07110 abbd5ec294430b03dde3372d57faea91 132 PIRSF PIRSF019455 1 131 4.6E-37 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A616_RS07110 abbd5ec294430b03dde3372d57faea91 132 SUPERFAMILY SSF46785 5 122 1.22E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07110 abbd5ec294430b03dde3372d57faea91 132 Pfam PF03965 Penicillinase repressor 8 121 9.1E-36 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A616_RS06890 ca1e93cb0942e64abba8ba3196cc47bd 786 Pfam PF13538 UvrD-like helicase C-terminal domain 721 764 4.3E-9 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain A616_RS06890 ca1e93cb0942e64abba8ba3196cc47bd 786 SUPERFAMILY SSF52540 507 770 9.51E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06890 ca1e93cb0942e64abba8ba3196cc47bd 786 SUPERFAMILY SSF52540 205 364 9.51E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06890 ca1e93cb0942e64abba8ba3196cc47bd 786 Gene3D G3DSA:3.40.50.300 211 610 1.2E-29 T 29-03-2018 A616_RS06890 ca1e93cb0942e64abba8ba3196cc47bd 786 Pfam PF13245 AAA domain 217 590 1.3E-11 T 29-03-2018 A616_RS06890 ca1e93cb0942e64abba8ba3196cc47bd 786 Gene3D G3DSA:3.40.50.300 615 785 1.5E-27 T 29-03-2018 A616_RS08410 866838e02bf6dde5c42af21f6e3e7316 228 SUPERFAMILY SSF52540 4 223 1.14E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08410 866838e02bf6dde5c42af21f6e3e7316 228 Pfam PF00005 ABC transporter 23 169 1.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08410 866838e02bf6dde5c42af21f6e3e7316 228 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08410 866838e02bf6dde5c42af21f6e3e7316 228 SMART SM00382 32 218 9.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08410 866838e02bf6dde5c42af21f6e3e7316 228 Gene3D G3DSA:3.40.50.300 1 226 4.4E-63 T 29-03-2018 A616_RS27040 f7156f0806876f9b4112a9e181a285ec 205 Pfam PF01865 Protein of unknown function DUF47 9 201 2.2E-20 T 29-03-2018 IPR018445 Putative phosphate transport regulator A616_RS27040 f7156f0806876f9b4112a9e181a285ec 205 Gene3D G3DSA:1.20.58.220 94 204 2.2E-10 T 29-03-2018 A616_RS27040 f7156f0806876f9b4112a9e181a285ec 205 SUPERFAMILY SSF109755 18 201 4.58E-5 T 29-03-2018 A616_RS18620 1d7cb46c0d797abf2893f9cca2e60c60 411 Pfam PF07730 Histidine kinase 207 270 1.4E-18 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS18620 1d7cb46c0d797abf2893f9cca2e60c60 411 SUPERFAMILY SSF55874 281 399 5.11E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18620 1d7cb46c0d797abf2893f9cca2e60c60 411 Gene3D G3DSA:3.30.565.10 270 408 1.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 172 3.1E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 SUPERFAMILY SSF88659 114 172 4.11E-19 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 Pfam PF04542 Sigma-70 region 2 24 87 5.7E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 Gene3D G3DSA:1.10.10.10 88 175 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 Pfam PF08281 Sigma-70, region 4 117 168 2.8E-21 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 SUPERFAMILY SSF88946 1 100 8.63E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11270 4c237f114a2b84d5bb6eec82272b3c0e 181 Gene3D G3DSA:1.10.1740.10 1 87 1.2E-23 T 29-03-2018 A616_RS19790 061803408f05676d98cae500712f7616 121 Pfam PF02033 Ribosome-binding factor A 5 108 4.3E-33 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A616_RS19790 061803408f05676d98cae500712f7616 121 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 23.4 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A616_RS19790 061803408f05676d98cae500712f7616 121 Gene3D G3DSA:3.30.300.20 3 115 2.1E-36 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS19790 061803408f05676d98cae500712f7616 121 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 A616_RS19790 061803408f05676d98cae500712f7616 121 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 95 3.0E-26 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A616_RS19790 061803408f05676d98cae500712f7616 121 SUPERFAMILY SSF89919 1 111 9.81E-37 T 29-03-2018 IPR023799 Ribosome-binding factor A domain A616_RS19790 061803408f05676d98cae500712f7616 121 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 113 5.2E-36 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A616_RS10740 befadcd22c1285c92c8a48ebe5d864c1 145 SUPERFAMILY SSF69500 1 144 1.31E-58 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain A616_RS10740 befadcd22c1285c92c8a48ebe5d864c1 145 Gene3D G3DSA:3.50.80.10 1 145 2.9E-60 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain A616_RS10740 befadcd22c1285c92c8a48ebe5d864c1 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 145 8.4E-61 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A616_RS10740 befadcd22c1285c92c8a48ebe5d864c1 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.164 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A616_RS10740 befadcd22c1285c92c8a48ebe5d864c1 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 2.3E-59 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A616_RS08495 7597fe95bc4c4f0e65c5be2d73789204 387 Pfam PF12849 PBP superfamily domain 135 372 1.3E-22 T 29-03-2018 IPR024370 PBP domain A616_RS08495 7597fe95bc4c4f0e65c5be2d73789204 387 Gene3D G3DSA:3.40.190.10 134 252 9.1E-22 T 29-03-2018 A616_RS08495 7597fe95bc4c4f0e65c5be2d73789204 387 SUPERFAMILY SSF53850 135 386 3.63E-51 T 29-03-2018 A616_RS08495 7597fe95bc4c4f0e65c5be2d73789204 387 Gene3D G3DSA:3.40.190.10 253 387 3.9E-19 T 29-03-2018 A616_RS18870 6fa5be0dfcbf1a22574cad216dd5c1d9 99 Pfam PF06949 Protein of unknown function (DUF1292) 19 90 1.5E-7 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 A616_RS10200 a7be8e9a9b11f92218af6bd25b261e9b 125 Pfam PF13038 Domain of unknown function (DUF3899) 32 120 3.9E-21 T 29-03-2018 IPR025007 Domain of unknown function DUF3899 A616_RS01810 458d53711dd45f4bb7cb5b8079ad1863 412 Pfam PF07690 Major Facilitator Superfamily 33 245 2.4E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS01810 458d53711dd45f4bb7cb5b8079ad1863 412 SUPERFAMILY SSF103473 13 407 1.44E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS01810 458d53711dd45f4bb7cb5b8079ad1863 412 Gene3D G3DSA:1.20.1250.20 2 216 2.1E-23 T 29-03-2018 A616_RS01810 458d53711dd45f4bb7cb5b8079ad1863 412 Gene3D G3DSA:1.20.1250.20 217 410 6.7E-12 T 29-03-2018 A616_RS19270 42e6e895a588120c94a572eed154d1a9 128 SUPERFAMILY SSF56349 1 112 2.18E-10 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS19270 42e6e895a588120c94a572eed154d1a9 128 Gene3D G3DSA:1.10.443.10 1 123 5.7E-8 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 Gene3D G3DSA:2.60.40.1080 175 258 1.9E-15 T 29-03-2018 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 Gene3D G3DSA:2.60.40.1080 6 88 2.9E-10 T 29-03-2018 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 SMART SM00635 175 257 0.0013 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 SMART SM00635 4 84 1.4 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 Gene3D G3DSA:2.60.40.10 259 358 2.6E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 Gene3D G3DSA:2.60.40.10 89 174 7.6E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 SUPERFAMILY SSF49265 252 350 1.73E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 SUPERFAMILY SSF49265 101 179 1.73E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS25740 1c508078c38176d93baf25ccbb78d454 382 SUPERFAMILY SSF49373 210 251 4.55E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08635 ac834241d79bbb291ddcd8e29cb8fe5d 252 Pfam PF00753 Metallo-beta-lactamase superfamily 23 224 3.2E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08635 ac834241d79bbb291ddcd8e29cb8fe5d 252 SMART SM00849 19 224 3.3E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08635 ac834241d79bbb291ddcd8e29cb8fe5d 252 Gene3D G3DSA:3.60.15.10 2 244 1.5E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08635 ac834241d79bbb291ddcd8e29cb8fe5d 252 SUPERFAMILY SSF56281 20 243 2.75E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 Pfam PF13377 Periplasmic binding protein-like domain 176 332 3.5E-28 T 29-03-2018 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 Gene3D G3DSA:3.40.50.2300 178 317 2.4E-32 T 29-03-2018 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 Gene3D G3DSA:3.40.50.2300 59 177 3.2E-24 T 29-03-2018 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 Gene3D G3DSA:1.10.260.40 7 58 1.6E-20 T 29-03-2018 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 3.4E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 3.4E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.4E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 SUPERFAMILY SSF53822 67 332 4.5E-52 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 29-03-2018 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 SUPERFAMILY SSF47413 5 64 9.38E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS08460 ccaa06317b8ceb017b1aee89fa4a0623 343 SMART SM00354 6 76 4.6E-29 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 SUPERFAMILY SSF52540 621 840 1.06E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 SMART SM00490 952 1034 6.7E-24 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 SMART SM00487 634 822 9.5E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 Gene3D G3DSA:3.40.50.300 913 1072 8.5E-40 T 29-03-2018 A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 SUPERFAMILY SSF52540 842 1089 2.23E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 Pfam PF00176 SNF2 family N-terminal domain 654 912 3.6E-51 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 Pfam PF04434 SWIM zinc finger 54 89 7.6E-4 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 Gene3D G3DSA:3.40.50.10810 608 898 1.9E-47 T 29-03-2018 A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 Pfam PF00271 Helicase conserved C-terminal domain 923 1034 1.3E-19 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS20560 6affa339196e8a90d5442b8a419c6032 1090 Pfam PF08455 Bacterial SNF2 helicase associated 254 631 5.3E-93 T 29-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 SUPERFAMILY SSF48008 86 213 4.45E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 Pfam PF07729 FCD domain 90 204 1.2E-18 T 29-03-2018 IPR011711 GntR, C-terminal A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 Gene3D G3DSA:1.20.120.530 85 219 7.4E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 47 9.5E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 47 66 9.5E-6 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 4.7E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 SUPERFAMILY SSF46785 7 80 4.88E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 SMART SM00895 86 208 3.2E-12 T 29-03-2018 IPR011711 GntR, C-terminal A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 Gene3D G3DSA:1.10.10.10 1 84 3.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15190 8b56f406a2d969dfbcbb710cf87e87d3 220 SMART SM00345 18 76 8.6E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS27785 ae0805e31c85b68aa7b42b0a4432a90f 382 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 353 2.7E-70 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS27785 ae0805e31c85b68aa7b42b0a4432a90f 382 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 217 352 4.0E-19 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS04555 b5a32e44478d782f3af0f7a9caa22311 339 Gene3D G3DSA:3.40.50.1980 46 174 2.1E-27 T 29-03-2018 A616_RS04555 b5a32e44478d782f3af0f7a9caa22311 339 Pfam PF01497 Periplasmic binding protein 78 313 1.4E-31 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS04555 b5a32e44478d782f3af0f7a9caa22311 339 SUPERFAMILY SSF53807 60 333 5.05E-61 T 29-03-2018 A616_RS04555 b5a32e44478d782f3af0f7a9caa22311 339 Gene3D G3DSA:3.40.50.1980 175 338 1.5E-29 T 29-03-2018 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 SUPERFAMILY SSF102114 197 433 1.1E-62 T 29-03-2018 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 Pfam PF01938 TRAM domain 440 498 1.3E-12 T 29-03-2018 IPR002792 TRAM domain A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 Pfam PF00919 Uncharacterized protein family UPF0004 63 164 2.2E-30 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 63 498 2.7E-196 T 29-03-2018 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 SMART SM00729 207 425 1.4E-63 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 62 499 73.585 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 Pfam PF04055 Radical SAM superfamily 211 382 4.6E-34 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 Gene3D G3DSA:3.80.30.20 205 439 3.4E-56 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 211 231 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 63 495 9.7E-158 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A616_RS19540 6e7bc8384a1fe2f37565cfb146c3c3fe 503 Gene3D G3DSA:2.40.50.140 441 500 9.8E-5 T 29-03-2018 A616_RS15100 51619908d76f1fa04b1c971133265810 359 SUPERFAMILY SSF69360 175 298 9.55E-11 T 29-03-2018 A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 286 327 4.9E-8 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 98 131 1.0E-10 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 63 95 1.5E-8 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 138 181 3.6E-5 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 253 284 5.2E-8 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 183 216 1.4E-6 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 327 356 0.0021 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 218 250 1.9E-6 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 Pfam PF14903 WG containing repeat 26 48 0.0013 T 29-03-2018 IPR032774 WG containing repeat A616_RS15100 51619908d76f1fa04b1c971133265810 359 SUPERFAMILY SSF69360 57 152 1.29E-6 T 29-03-2018 A616_RS15100 51619908d76f1fa04b1c971133265810 359 Gene3D G3DSA:2.10.270.10 173 348 1.4E-5 T 29-03-2018 A616_RS15100 51619908d76f1fa04b1c971133265810 359 Gene3D G3DSA:2.10.270.10 21 124 0.22 T 29-03-2018 A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 SUPERFAMILY SSF90123 12 312 1.23E-26 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 SUPERFAMILY SSF90123 498 503 1.23E-26 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 Gene3D G3DSA:1.20.1560.10 4 338 3.8E-22 T 29-03-2018 A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 SMART SM00382 377 568 8.2E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 Pfam PF00005 ABC transporter 368 522 7.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 Gene3D G3DSA:3.40.50.300 342 597 4.7E-72 T 29-03-2018 A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 SUPERFAMILY SSF52540 341 592 5.97E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30135 bae0e6d39a645c3c6932efe867e75397 603 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25580 e19c38f273e3807f54f6cc226781ed49 239 Pfam PF00929 Exonuclease 4 169 3.9E-13 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS25580 e19c38f273e3807f54f6cc226781ed49 239 SUPERFAMILY SSF53098 3 173 2.9E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS25580 e19c38f273e3807f54f6cc226781ed49 239 SMART SM00479 2 179 5.3E-7 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS25580 e19c38f273e3807f54f6cc226781ed49 239 Gene3D G3DSA:3.30.420.10 2 192 2.0E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS03295 9c27bacd4cbbfcae5bb168d76393f534 176 Pfam PF02417 Chromate transporter 4 171 2.2E-34 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 452 1.1E-182 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 SUPERFAMILY SSF53448 4 253 2.7E-68 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 267 295 0.011 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Gene3D G3DSA:2.160.10.10 314 444 1.9E-33 T 29-03-2018 A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 SUPERFAMILY SSF51161 254 441 9.98E-46 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.553 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 2.2E-4 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 352 382 0.0016 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 319 351 8.1E-6 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Gene3D G3DSA:3.90.550.10 1 245 1.0E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Pfam PF00483 Nucleotidyl transferase 6 217 2.9E-23 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS00680 9d533ca6b5f4099d408794258c65a0cd 461 Gene3D G3DSA:2.160.10.10 246 313 8.0E-15 T 29-03-2018 A616_RS18315 29a89cee353a9fe254998e96a0212137 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.7E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS18315 29a89cee353a9fe254998e96a0212137 85 Gene3D G3DSA:3.30.1340.10 1 85 1.1E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS18315 29a89cee353a9fe254998e96a0212137 85 SUPERFAMILY SSF55594 1 81 1.14E-25 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS18315 29a89cee353a9fe254998e96a0212137 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A616_RS18315 29a89cee353a9fe254998e96a0212137 85 Pfam PF00381 PTS HPr component phosphorylation site 3 81 4.1E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS18315 29a89cee353a9fe254998e96a0212137 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A616_RS18315 29a89cee353a9fe254998e96a0212137 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 5.6E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS18315 29a89cee353a9fe254998e96a0212137 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 5.6E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS18315 29a89cee353a9fe254998e96a0212137 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 5.6E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS24915 3d21d456a952b948a7a6be866c6967ff 115 Pfam PF08818 Domain of unknown function (DU1801) 19 110 9.5E-16 T 29-03-2018 IPR014922 Domain of unknown function DUF1801 A616_RS24915 3d21d456a952b948a7a6be866c6967ff 115 SUPERFAMILY SSF159888 3 109 1.23E-20 T 29-03-2018 A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 Gene3D G3DSA:3.40.50.720 1 53 9.1E-10 T 29-03-2018 A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 Gene3D G3DSA:3.40.50.720 54 250 6.0E-53 T 29-03-2018 A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 SUPERFAMILY SSF51735 6 244 1.84E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 1.5E-64 T 29-03-2018 A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 7.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 7.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 7.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02390 35b47ab7f2b6b256943bd949090145f7 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.1E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS24575 e23de44b5af9d1f8c2e2a082d444fb07 279 Gene3D G3DSA:3.60.40.10 38 276 1.3E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS24575 e23de44b5af9d1f8c2e2a082d444fb07 279 SMART SM00331 25 277 2.4E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS24575 e23de44b5af9d1f8c2e2a082d444fb07 279 SUPERFAMILY SSF81606 38 275 1.31E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS24575 e23de44b5af9d1f8c2e2a082d444fb07 279 SMART SM00332 31 275 8.5E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS24575 e23de44b5af9d1f8c2e2a082d444fb07 279 Pfam PF13672 Protein phosphatase 2C 46 240 4.5E-16 T 29-03-2018 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SUPERFAMILY SSF53098 314 461 2.73E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SUPERFAMILY SSF50249 630 714 8.95E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SMART SM00316 644 715 1.6E-18 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Pfam PF16921 Tex protein YqgF-like domain 318 443 2.9E-56 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Gene3D G3DSA:1.10.150.310 491 625 4.3E-44 T 29-03-2018 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SUPERFAMILY SSF158832 6 313 1.2E-116 T 29-03-2018 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Pfam PF12836 Helix-hairpin-helix motif 483 547 2.0E-24 T 29-03-2018 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Gene3D G3DSA:1.10.3500.10 348 490 8.0E-43 T 29-03-2018 IPR023323 Tex-like domain A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Pfam PF09371 Tex-like protein N-terminal domain 10 193 1.2E-71 T 29-03-2018 IPR018974 Tex-like protein, N-terminal A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Gene3D G3DSA:2.40.50.140 639 719 3.1E-21 T 29-03-2018 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Pfam PF00575 S1 RNA binding domain 645 713 2.1E-13 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Gene3D G3DSA:1.10.10.650 4 102 1.8E-35 T 29-03-2018 IPR023319 Tex-like protein, HTH domain A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SUPERFAMILY SSF47781 462 548 5.45E-25 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SMART SM00732 318 416 2.2E-34 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 Gene3D G3DSA:1.10.3500.10 103 347 7.2E-84 T 29-03-2018 IPR023323 Tex-like domain A616_RS02920 e30611414dc47412510f5e7460b1aee4 720 SUPERFAMILY SSF47781 553 627 1.49E-16 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 Gene3D G3DSA:1.10.1740.10 1 91 2.1E-28 T 29-03-2018 A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 172 2.9E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 SUPERFAMILY SSF88659 106 173 5.79E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 Pfam PF04542 Sigma-70 region 2 23 90 2.5E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 Pfam PF08281 Sigma-70, region 4 118 169 1.3E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 Gene3D G3DSA:1.10.10.10 92 176 2.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 44 75 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02320 1dab9b9ac482d580e6bfd24006fa2d1d 188 SUPERFAMILY SSF88946 3 106 9.22E-30 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05305 cd19d883ac595f9cdd954f238e7ea0af 339 SUPERFAMILY SSF141986 192 326 4.71E-28 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain A616_RS05305 cd19d883ac595f9cdd954f238e7ea0af 339 SUPERFAMILY SSF52317 1 162 3.48E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS05305 cd19d883ac595f9cdd954f238e7ea0af 339 PIRSF PIRSF028757 1 336 5.5E-62 T 29-03-2018 IPR003507 Peptidase family S66 A616_RS05305 cd19d883ac595f9cdd954f238e7ea0af 339 Gene3D G3DSA:3.50.30.60 163 336 6.2E-41 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain A616_RS05305 cd19d883ac595f9cdd954f238e7ea0af 339 Gene3D G3DSA:3.40.50.10740 1 162 2.4E-38 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain A616_RS05305 cd19d883ac595f9cdd954f238e7ea0af 339 Pfam PF02016 LD-carboxypeptidase 13 324 5.6E-68 T 29-03-2018 IPR003507 Peptidase family S66 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 Pfam PF04542 Sigma-70 region 2 13 76 2.1E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 SUPERFAMILY SSF88659 89 162 4.49E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 33 63 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 SUPERFAMILY SSF88946 9 90 2.88E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 Gene3D G3DSA:1.10.10.10 71 163 1.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 Gene3D G3DSA:1.10.1740.10 2 70 1.2E-18 T 29-03-2018 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 162 3.9E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05510 b8a7d9661a888d1493d8ed1aeb88d658 176 Pfam PF08281 Sigma-70, region 4 107 158 2.5E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SUPERFAMILY SSF48371 204 373 2.37E-30 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 Gene3D G3DSA:3.30.1370.70 2 86 1.3E-17 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 Gene3D G3DSA:1.25.40.70 205 297 1.6E-15 T 29-03-2018 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 Gene3D G3DSA:1.25.40.70 298 360 6.3E-9 T 29-03-2018 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 Pfam PF13769 Virulence factor 110 190 8.7E-30 T 29-03-2018 IPR025989 Virulence factor domain A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 Pfam PF13646 HEAT repeats 271 346 1.1E-11 T 29-03-2018 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SMART SM00932 4 86 3.1E-14 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SMART SM00567 E-Z type HEAT repeats 313 342 3.4E-4 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SMART SM00567 E-Z type HEAT repeats 222 249 400.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SMART SM00567 E-Z type HEAT repeats 251 280 0.0099 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SMART SM00567 E-Z type HEAT repeats 282 311 0.031 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 5 84 5.2E-17 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A616_RS11145 07dd3f90a950b4afbdfd737100980bb3 376 SUPERFAMILY SSF110836 1 83 1.83E-18 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal A616_RS28575 639a970f97ddcae1da5b555b89c2aa39 431 SUPERFAMILY SSF103473 17 424 1.44E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS28575 639a970f97ddcae1da5b555b89c2aa39 431 Gene3D G3DSA:1.20.1250.20 236 431 1.8E-23 T 29-03-2018 A616_RS28575 639a970f97ddcae1da5b555b89c2aa39 431 Pfam PF07690 Major Facilitator Superfamily 42 346 1.9E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS28575 639a970f97ddcae1da5b555b89c2aa39 431 Gene3D G3DSA:1.20.1250.20 16 223 5.5E-23 T 29-03-2018 A616_RS14005 c699cf1b275975108dc437d817f2d098 503 Gene3D G3DSA:3.40.50.300 51 264 3.8E-52 T 29-03-2018 A616_RS14005 c699cf1b275975108dc437d817f2d098 503 SMART SM00382 105 249 1.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14005 c699cf1b275975108dc437d817f2d098 503 ProSitePatterns PS00674 AAA-protein family signature. 217 235 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A616_RS14005 c699cf1b275975108dc437d817f2d098 503 SUPERFAMILY SSF140990 329 497 2.75E-43 T 29-03-2018 A616_RS14005 c699cf1b275975108dc437d817f2d098 503 Pfam PF01434 Peptidase family M41 308 492 1.1E-35 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A616_RS14005 c699cf1b275975108dc437d817f2d098 503 SUPERFAMILY SSF52540 69 318 2.45E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14005 c699cf1b275975108dc437d817f2d098 503 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 109 246 3.4E-40 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS14005 c699cf1b275975108dc437d817f2d098 503 Gene3D G3DSA:1.10.8.60 265 340 3.4E-21 T 29-03-2018 A616_RS14040 7da35e379360ee875d614a4146d56424 267 Pfam PF00535 Glycosyl transferase family 2 6 151 1.8E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS14040 7da35e379360ee875d614a4146d56424 267 SUPERFAMILY SSF53448 3 230 5.63E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS14040 7da35e379360ee875d614a4146d56424 267 Gene3D G3DSA:3.90.550.10 1 262 2.6E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 182 2.7E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Pfam PF00009 Elongation factor Tu GTP binding domain 8 187 3.0E-54 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Gene3D G3DSA:2.40.30.10 194 293 4.1E-27 T 29-03-2018 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 SUPERFAMILY SSF54980 298 376 2.88E-19 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.5E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 SUPERFAMILY SSF52540 6 211 3.98E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Pfam PF06421 GTP-binding protein LepA C-terminus 494 600 6.3E-52 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 SUPERFAMILY SSF50447 172 294 2.29E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Gene3D G3DSA:3.40.50.300 5 191 1.6E-37 T 29-03-2018 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Pfam PF03144 Elongation factor Tu domain 2 211 281 8.0E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 SMART SM00838 407 492 2.3E-4 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 SUPERFAMILY SSF54980 405 500 2.25E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Gene3D G3DSA:3.30.70.870 294 373 1.8E-29 T 29-03-2018 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Hamap MF_00071 Elongation factor 4 [lepA]. 1 604 314.104 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Gene3D G3DSA:3.30.70.240 395 556 1.1E-30 T 29-03-2018 A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 Pfam PF00679 Elongation factor G C-terminus 405 492 3.0E-24 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS11395 c822969a9858a0a1d8ca2cd107c27e1c 605 TIGRFAM TIGR01393 lepA: elongation factor 4 8 602 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 A616_RS00805 76a0bc1fe4517a4b7caa2efa4a81786b 289 SUPERFAMILY SSF56784 7 283 2.68E-62 T 29-03-2018 IPR023214 HAD-like domain A616_RS00805 76a0bc1fe4517a4b7caa2efa4a81786b 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 252 1.5E-23 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A616_RS00805 76a0bc1fe4517a4b7caa2efa4a81786b 289 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 279 1.6E-52 T 29-03-2018 IPR000150 Cof family GO:0016787 A616_RS00805 76a0bc1fe4517a4b7caa2efa4a81786b 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 279 3.0E-55 T 29-03-2018 IPR023214 HAD-like domain A616_RS00805 76a0bc1fe4517a4b7caa2efa4a81786b 289 Gene3D G3DSA:3.40.50.1000 4 288 2.0E-39 T 29-03-2018 IPR023214 HAD-like domain A616_RS00805 76a0bc1fe4517a4b7caa2efa4a81786b 289 ProSitePatterns PS01229 Hypothetical cof family signature 2. 233 255 - T 29-03-2018 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 Gene3D G3DSA:3.40.50.150 65 272 9.5E-61 T 29-03-2018 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 SUPERFAMILY SSF53335 57 249 4.9E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 PIRSF PIRSF005578 1 264 1.3E-100 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 SUPERFAMILY SSF55174 5 71 2.65E-11 T 29-03-2018 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 Pfam PF01479 S4 domain 6 46 1.3E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 Pfam PF01728 FtsJ-like methyltransferase 62 243 3.1E-16 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 Gene3D G3DSA:3.10.290.10 2 64 1.0E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 3.4E-83 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 A616_RS13155 4c8c10cc4dcf3282627e4fb52f9539c3 272 SMART SM00363 6 71 6.3E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS26485 c5ac817204dd112846ed7bcf4b5a1e44 731 SUPERFAMILY SSF52540 618 715 1.09E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26485 c5ac817204dd112846ed7bcf4b5a1e44 731 SUPERFAMILY SSF52540 1 132 1.09E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26485 c5ac817204dd112846ed7bcf4b5a1e44 731 Pfam PF13476 AAA domain 6 232 1.0E-16 T 29-03-2018 A616_RS26485 c5ac817204dd112846ed7bcf4b5a1e44 731 Gene3D G3DSA:3.40.50.300 1 727 6.4E-25 T 29-03-2018 A616_RS26485 c5ac817204dd112846ed7bcf4b5a1e44 731 SUPERFAMILY SSF52540 411 712 3.66E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 600 1.2E-291 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Pfam PF00679 Elongation factor G C-terminus 397 476 4.2E-22 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Pfam PF14492 Elongation Factor G, domain II 328 377 1.5E-6 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Gene3D G3DSA:3.30.70.870 303 401 6.3E-33 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 140 6.4E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Gene3D G3DSA:3.40.50.300 69 189 4.1E-29 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 SUPERFAMILY SSF52540 5 208 1.69E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 SUPERFAMILY SSF54980 399 514 1.44E-27 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Gene3D G3DSA:2.40.50.250 484 574 4.9E-40 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Pfam PF03144 Elongation factor Tu domain 2 220 290 4.7E-11 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 PRINTS PR00315 GTP-binding elongation factor signature 52 60 8.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 PRINTS PR00315 GTP-binding elongation factor signature 8 21 8.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 PRINTS PR00315 GTP-binding elongation factor signature 72 82 8.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 PRINTS PR00315 GTP-binding elongation factor signature 88 99 8.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 PRINTS PR00315 GTP-binding elongation factor signature 124 133 8.8E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Gene3D G3DSA:3.40.50.300 1 68 5.4E-9 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Gene3D G3DSA:2.40.30.10 190 301 7.9E-23 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Pfam PF00009 Elongation factor Tu GTP binding domain 5 196 4.5E-57 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 Gene3D G3DSA:3.30.70.240 402 480 1.3E-16 T 29-03-2018 A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 SUPERFAMILY SSF54980 303 388 3.96E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS21530 98a9f9c6a71c95da8f2a7c9fd2d4f19f 613 SUPERFAMILY SSF50447 152 300 2.83E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Pfam PF01225 Mur ligase family, catalytic domain 27 75 1.5E-6 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 454 6.2E-119 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Gene3D G3DSA:3.40.1190.10 98 316 3.6E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 457 31.072 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Gene3D G3DSA:3.90.190.20 319 460 4.9E-32 T 29-03-2018 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 SUPERFAMILY SSF53244 322 455 1.72E-27 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Gene3D G3DSA:3.40.1390.10 3 97 5.9E-21 T 29-03-2018 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 322 400 5.2E-13 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 SUPERFAMILY SSF53623 108 317 7.06E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 Pfam PF08245 Mur ligase middle domain 113 300 6.1E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS11580 d8a7d1a0b6bf58cc59d9870049a7c75a 460 SUPERFAMILY SSF63418 18 104 4.05E-20 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 Gene3D G3DSA:1.20.5.170 201 223 3.1E-10 T 29-03-2018 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 SUPERFAMILY SSF52413 300 418 3.92E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 Gene3D G3DSA:3.40.50.720 224 425 5.8E-50 T 29-03-2018 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 SMART SM00984 317 418 3.0E-24 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 417 6.1E-19 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 SUPERFAMILY SSF48179 201 292 1.7E-23 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 290 4.4E-22 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 8 402 3.1E-111 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 8 181 3.5E-33 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 PIRSF PIRSF000124 7 426 2.9E-48 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 Gene3D G3DSA:3.40.50.720 5 198 4.2E-38 T 29-03-2018 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 PIRSF PIRSF500136 2 430 1.7E-138 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A616_RS23445 8321e583385e0493c8f2cc2e98972a67 430 SUPERFAMILY SSF51735 7 192 9.44E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15985 69d3135f183d7598687c1f2940312991 750 SUPERFAMILY SSF52540 466 723 6.25E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15985 69d3135f183d7598687c1f2940312991 750 Pfam PF00005 ABC transporter 470 673 5.8E-13 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15985 69d3135f183d7598687c1f2940312991 750 Gene3D G3DSA:3.40.50.300 457 750 2.1E-55 T 29-03-2018 A616_RS15985 69d3135f183d7598687c1f2940312991 750 Gene3D G3DSA:3.40.50.300 21 61 0.002 T 29-03-2018 A616_RS15985 69d3135f183d7598687c1f2940312991 750 SUPERFAMILY SSF52540 9 126 1.99E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15985 69d3135f183d7598687c1f2940312991 750 SUPERFAMILY SSF52540 326 429 1.99E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15985 69d3135f183d7598687c1f2940312991 750 SUPERFAMILY SSF52540 165 195 1.99E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15985 69d3135f183d7598687c1f2940312991 750 Gene3D G3DSA:1.20.1580.10 98 338 7.5E-50 T 29-03-2018 A616_RS15985 69d3135f183d7598687c1f2940312991 750 ProSitePatterns PS00211 ABC transporters family signature. 646 660 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15985 69d3135f183d7598687c1f2940312991 750 Gene3D G3DSA:3.40.50.300 339 411 0.13 T 29-03-2018 A616_RS11595 d1c4f5b74adedd27f3d08718499cc5c6 148 Gene3D G3DSA:1.10.1510.10 1 90 4.1E-29 T 29-03-2018 A616_RS11595 d1c4f5b74adedd27f3d08718499cc5c6 148 Pfam PF09424 Yqey-like protein 5 146 3.3E-53 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial A616_RS11595 d1c4f5b74adedd27f3d08718499cc5c6 148 Gene3D G3DSA:1.10.10.410 91 147 4.8E-19 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A616_RS11595 d1c4f5b74adedd27f3d08718499cc5c6 148 SUPERFAMILY SSF89095 1 146 7.85E-42 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A616_RS00410 696cfce85a23ef915bbd6ac131ba8221 100 Pfam PF12840 Helix-turn-helix domain 5 77 3.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00410 696cfce85a23ef915bbd6ac131ba8221 100 SUPERFAMILY SSF46785 3 96 3.45E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00410 696cfce85a23ef915bbd6ac131ba8221 100 Gene3D G3DSA:1.10.10.10 2 95 1.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00410 696cfce85a23ef915bbd6ac131ba8221 100 SMART SM00418 5 98 1.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 Gene3D G3DSA:1.20.1250.20 1 192 1.1E-37 T 29-03-2018 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 SUPERFAMILY SSF103473 241 412 1.09E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 SUPERFAMILY SSF103473 445 473 1.09E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 SUPERFAMILY SSF103473 2 188 1.09E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 Gene3D G3DSA:1.20.1250.20 245 483 1.5E-29 T 29-03-2018 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 Pfam PF07690 Major Facilitator Superfamily 9 403 1.3E-55 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 8 32 5.4E-8 T 29-03-2018 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 67 89 5.4E-8 T 29-03-2018 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 393 412 5.4E-8 T 29-03-2018 A616_RS09340 1cb3211ed5465a256895c4e6cee4c35c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 5.4E-8 T 29-03-2018 A616_RS25510 97e8368a9731b31d37e6f760ef27e99a 157 Pfam PF02308 MgtC family 20 149 3.7E-30 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS25510 97e8368a9731b31d37e6f760ef27e99a 157 PRINTS PR01837 MgtC/SapB protein signature 41 59 2.2E-36 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS25510 97e8368a9731b31d37e6f760ef27e99a 157 PRINTS PR01837 MgtC/SapB protein signature 22 41 2.2E-36 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS25510 97e8368a9731b31d37e6f760ef27e99a 157 PRINTS PR01837 MgtC/SapB protein signature 103 127 2.2E-36 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS25510 97e8368a9731b31d37e6f760ef27e99a 157 PRINTS PR01837 MgtC/SapB protein signature 76 98 2.2E-36 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS14305 f5f379118378ee492473051f1c59f7f5 185 Pfam PF12822 ECF transporter, substrate-specific component 8 164 8.9E-27 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 5.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 5.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 5.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 Gene3D G3DSA:3.40.50.1820 2 269 6.7E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 SUPERFAMILY SSF53474 2 268 6.03E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 PRINTS PR00412 Epoxide hydrolase signature 29 47 9.3E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 PRINTS PR00412 Epoxide hydrolase signature 49 64 9.3E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 PRINTS PR00412 Epoxide hydrolase signature 244 266 9.3E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS09075 dc397844eaab08831fcb00c3f19c99b6 269 Pfam PF00561 alpha/beta hydrolase fold 24 249 1.5E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS23090 a97e27f1622316a37084ff1259399301 415 SUPERFAMILY SSF103473 10 406 1.44E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS23090 a97e27f1622316a37084ff1259399301 415 PRINTS PR01035 Tetracycline resistance protein signature 349 372 9.4E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23090 a97e27f1622316a37084ff1259399301 415 PRINTS PR01035 Tetracycline resistance protein signature 21 37 9.4E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23090 a97e27f1622316a37084ff1259399301 415 PRINTS PR01035 Tetracycline resistance protein signature 136 158 9.4E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23090 a97e27f1622316a37084ff1259399301 415 Gene3D G3DSA:1.20.1250.20 214 414 2.6E-26 T 29-03-2018 A616_RS23090 a97e27f1622316a37084ff1259399301 415 Pfam PF07690 Major Facilitator Superfamily 15 285 1.3E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS23090 a97e27f1622316a37084ff1259399301 415 Gene3D G3DSA:1.20.1250.20 9 201 1.5E-23 T 29-03-2018 A616_RS25000 81e004681f0606f7cf351ce22deb7451 373 Pfam PF00155 Aminotransferase class I and II 49 361 1.5E-41 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS25000 81e004681f0606f7cf351ce22deb7451 373 Gene3D G3DSA:3.40.640.10 46 257 2.5E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS25000 81e004681f0606f7cf351ce22deb7451 373 Gene3D G3DSA:3.90.1150.10 258 373 6.3E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS25000 81e004681f0606f7cf351ce22deb7451 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 220 233 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A616_RS25000 81e004681f0606f7cf351ce22deb7451 373 SUPERFAMILY SSF53383 44 370 6.45E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS25370 31cbdd5203c022a82b4e2fdb7f8e52fd 118 Pfam PF01152 Bacterial-like globin 4 115 9.3E-28 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 A616_RS25370 31cbdd5203c022a82b4e2fdb7f8e52fd 118 PIRSF PIRSF002030 1 118 3.1E-43 T 29-03-2018 IPR016339 Truncated hemoglobin, group 1 A616_RS25370 31cbdd5203c022a82b4e2fdb7f8e52fd 118 Gene3D G3DSA:1.10.490.10 3 118 2.5E-36 T 29-03-2018 A616_RS25370 31cbdd5203c022a82b4e2fdb7f8e52fd 118 SUPERFAMILY SSF46458 3 116 4.03E-35 T 29-03-2018 IPR009050 Globin-like A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 SUPERFAMILY SSF55031 187 290 4.19E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 Pfam PF07687 Peptidase dimerisation domain 187 278 2.3E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 Gene3D G3DSA:3.40.630.10 367 458 6.4E-15 T 29-03-2018 A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 Gene3D G3DSA:3.40.630.10 1 363 4.3E-49 T 29-03-2018 A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 PIRSF PIRSF037227 1 473 1.5E-212 T 29-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 SUPERFAMILY SSF53187 6 199 1.33E-61 T 29-03-2018 A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 SUPERFAMILY SSF53187 376 440 1.33E-61 T 29-03-2018 A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 SUPERFAMILY SSF53187 299 328 1.33E-61 T 29-03-2018 A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 424 1.1E-84 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS25980 cb6f8defa340a071f7f7e44ad5242d7c 473 Pfam PF01546 Peptidase family M20/M25/M40 80 391 1.3E-8 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 426 45.937 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 Pfam PF01979 Amidohydrolase family 50 422 1.9E-52 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 18 425 1.2E-139 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 Gene3D G3DSA:3.20.20.140 69 408 1.4E-107 T 29-03-2018 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 SUPERFAMILY SSF51556 54 368 1.58E-109 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 SUPERFAMILY SSF51338 1 53 4.32E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 SUPERFAMILY SSF51338 368 425 4.32E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS21010 425ea37c63b53562bf7abb739ded7628 426 Gene3D G3DSA:2.30.40.10 2 68 1.5E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS19670 c18d6b711ded3d4ba19b1945fda9d90b 431 Gene3D G3DSA:3.30.830.10 246 423 1.6E-27 T 29-03-2018 A616_RS19670 c18d6b711ded3d4ba19b1945fda9d90b 431 Gene3D G3DSA:3.30.830.10 20 229 5.9E-21 T 29-03-2018 A616_RS19670 c18d6b711ded3d4ba19b1945fda9d90b 431 Pfam PF05193 Peptidase M16 inactive domain 188 364 9.3E-23 T 29-03-2018 IPR007863 Peptidase M16, C-terminal A616_RS19670 c18d6b711ded3d4ba19b1945fda9d90b 431 SUPERFAMILY SSF63411 250 418 1.62E-29 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A616_RS19670 c18d6b711ded3d4ba19b1945fda9d90b 431 SUPERFAMILY SSF63411 16 229 4.95E-21 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 SUPERFAMILY SSF48557 34 471 5.03E-97 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 1.8E-25 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 1.8E-25 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 1.8E-25 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 1.8E-25 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 1.8E-25 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 7.7E-19 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 7.7E-19 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 7.7E-19 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 7.7E-19 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 Pfam PF14698 Argininosuccinate lyase C-terminal 370 446 3.3E-15 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 Gene3D G3DSA:1.10.275.10 21 110 6.8E-14 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 Gene3D G3DSA:1.10.40.30 378 448 2.3E-16 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 TIGRFAM TIGR00838 argH: argininosuccinate lyase 36 471 2.0E-98 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 469 29.114 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 Gene3D G3DSA:1.20.200.10 111 377 3.0E-65 T 29-03-2018 A616_RS24950 c716eb27f4b898f3443c229e13e95de0 502 Pfam PF00206 Lyase 100 304 1.3E-40 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 Pfam PF04397 LytTr DNA-binding domain 143 240 1.1E-24 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 SMART SM00448 3 114 3.8E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 Gene3D G3DSA:2.40.50.40 138 202 6.1E-17 T 29-03-2018 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 Gene3D G3DSA:2.20.25.10 203 241 3.0E-11 T 29-03-2018 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 Pfam PF00072 Response regulator receiver domain 5 114 1.3E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 SMART SM00850 142 241 1.8E-32 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 ProDom PD017604 DEHYDROGENASE METHYLENETETRAHYDROMETHANOPTERIN F420-DEPENDENT MTD COENZYME DEPENDENT F420 N5N10- ONE-CARBON METABOLISM 10 107 0.001 T 29-03-2018 IPR002844 Methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 Gene3D G3DSA:3.40.50.2300 2 137 2.5E-27 T 29-03-2018 A616_RS12290 6240936a8b581d2f794a19278c22d8a6 242 SUPERFAMILY SSF52172 2 170 9.39E-30 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 Gene3D G3DSA:3.30.70.260 256 339 5.3E-24 T 29-03-2018 A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 Gene3D G3DSA:3.40.50.300 1 255 8.9E-75 T 29-03-2018 A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 SMART SM00382 30 218 8.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 SUPERFAMILY SSF52540 1 240 7.14E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 Pfam PF00005 ABC transporter 21 169 6.7E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 SUPERFAMILY SSF55021 249 338 3.32E-20 T 29-03-2018 A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 Pfam PF09383 NIL domain 266 336 2.0E-19 T 29-03-2018 IPR018449 NIL domain A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 SMART SM00930 263 338 7.2E-22 T 29-03-2018 IPR018449 NIL domain A616_RS15040 0a6b7b610dd37a3810ab4cfe1e796223 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 419 45.651 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 SMART SM00996 6 419 4.1E-120 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 SUPERFAMILY SSF52283 5 187 1.76E-90 T 29-03-2018 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 SUPERFAMILY SSF52283 350 418 1.76E-90 T 29-03-2018 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 9 418 2.4E-183 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 347 1.7E-54 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Gene3D G3DSA:3.40.50.1480 1 141 6.9E-45 T 29-03-2018 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 SUPERFAMILY SSF51735 188 350 3.49E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Gene3D G3DSA:3.40.50.1480 142 208 9.2E-9 T 29-03-2018 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Gene3D G3DSA:3.40.50.1480 209 402 2.0E-59 T 29-03-2018 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 SMART SM00997 188 349 1.3E-106 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 8 138 1.4E-27 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 142 415 4.2E-22 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS21345 ea319ecaf7a83ca5613ef6211f7d0363 419 PIRSF PIRSF001109 1 419 6.5E-176 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A616_RS29075 e5b7a5804b25c3570a54fc01e4bc2361 346 SUPERFAMILY SSF81345 15 341 9.15E-82 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS29075 e5b7a5804b25c3570a54fc01e4bc2361 346 Pfam PF01032 FecCD transport family 32 341 8.8E-92 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS29075 e5b7a5804b25c3570a54fc01e4bc2361 346 Gene3D G3DSA:1.10.3470.10 17 346 6.5E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS19370 0ce560204e9112b61a2599efcfa524ec 179 SUPERFAMILY SSF51110 21 79 9.16E-9 T 29-03-2018 IPR001480 Bulb-type lectin domain A616_RS19370 0ce560204e9112b61a2599efcfa524ec 179 Gene3D G3DSA:2.90.10.10 20 179 7.6E-18 T 29-03-2018 IPR001480 Bulb-type lectin domain A616_RS22435 4a4f492b1b6f5d45cbdae88e5be2502b 405 Pfam PF07690 Major Facilitator Superfamily 29 350 5.8E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS22435 4a4f492b1b6f5d45cbdae88e5be2502b 405 SUPERFAMILY SSF103473 18 399 1.7E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS22435 4a4f492b1b6f5d45cbdae88e5be2502b 405 Gene3D G3DSA:1.20.1250.20 208 400 2.8E-22 T 29-03-2018 A616_RS22435 4a4f492b1b6f5d45cbdae88e5be2502b 405 Gene3D G3DSA:1.20.1250.20 20 207 1.5E-20 T 29-03-2018 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 Pfam PF05683 Fumarase C-terminus 303 493 3.5E-61 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 SUPERFAMILY SSF117457 321 491 3.66E-52 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 330 491 5.9E-51 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 Pfam PF05681 Fumarate hydratase (Fumerase) 6 281 3.9E-72 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 PIRSF PIRSF001394 1 510 1.4E-183 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 281 4.2E-63 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A616_RS12170 ca17d9cfcdfcd19d24128736a733e4eb 511 Gene3D G3DSA:3.20.130.10 319 492 1.3E-63 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 SMART SM00862 147 223 3.1E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 Pfam PF00072 Response regulator receiver domain 4 112 7.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 Gene3D G3DSA:1.10.10.10 124 227 1.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 SMART SM00448 2 112 4.4E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 SUPERFAMILY SSF52172 2 176 2.85E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 Gene3D G3DSA:3.40.50.2300 1 123 2.6E-32 T 29-03-2018 A616_RS08720 201ba5a0b7323d35f233b442dc06f833 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 4.4E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 Pfam PF00196 Bacterial regulatory proteins, luxR family 11 63 4.4E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 SMART SM00421 8 65 7.4E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 Gene3D G3DSA:1.10.10.10 2 73 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 25 41 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 11 25 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 41 53 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 SUPERFAMILY SSF46894 8 71 6.12E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS09845 3b3abb60aced59bc5020a1a336e79a9e 73 ProSitePatterns PS00622 LuxR-type HTH domain signature. 25 52 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02560 47869608a8db5bbfbf44320280c367a3 231 Gene3D G3DSA:3.90.230.10 7 199 2.4E-19 T 29-03-2018 A616_RS02560 47869608a8db5bbfbf44320280c367a3 231 SUPERFAMILY SSF55920 30 198 1.22E-22 T 29-03-2018 IPR000994 Peptidase M24 A616_RS02560 47869608a8db5bbfbf44320280c367a3 231 Pfam PF00557 Metallopeptidase family M24 13 196 1.7E-18 T 29-03-2018 IPR000994 Peptidase M24 A616_RS23185 759b2c51759654010abb5395a09d9c41 248 Pfam PF01614 Bacterial transcriptional regulator 129 241 2.5E-22 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal A616_RS23185 759b2c51759654010abb5395a09d9c41 248 SMART SM00346 9 98 5.9E-25 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS23185 759b2c51759654010abb5395a09d9c41 248 Gene3D G3DSA:3.30.450.40 74 248 2.8E-37 T 29-03-2018 IPR029016 GAF domain-like A616_RS23185 759b2c51759654010abb5395a09d9c41 248 Pfam PF09339 IclR helix-turn-helix domain 11 60 7.4E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS23185 759b2c51759654010abb5395a09d9c41 248 Gene3D G3DSA:1.10.10.10 1 69 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23185 759b2c51759654010abb5395a09d9c41 248 SUPERFAMILY SSF46785 9 79 7.61E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23185 759b2c51759654010abb5395a09d9c41 248 SUPERFAMILY SSF55781 66 247 1.06E-40 T 29-03-2018 IPR029016 GAF domain-like A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF52777 2913 3175 2.45E-35 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:2.30.38.10 2442 2522 1.9E-21 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:2.30.38.10 1377 1459 1.0E-19 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:2.30.38.10 314 396 1.8E-20 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF56801 2087 2650 5.63E-147 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF52777 1667 1844 8.89E-49 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF13193 AMP-binding enzyme C-terminal domain 2540 2611 2.0E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 485 7.6E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00668 Condensation domain 1663 2109 7.6E-116 T 29-03-2018 IPR001242 Condensation domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00668 Condensation domain 597 1044 2.0E-118 T 29-03-2018 IPR001242 Condensation domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00668 Condensation domain 2731 3182 1.8E-73 T 29-03-2018 IPR001242 Condensation domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.30.559.10 2707 2933 5.8E-29 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF52777 1853 2116 3.78E-62 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF47336 2630 2702 1.57E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.40.50.980 2120 2277 1.5E-40 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.40.50.980 1 155 8.3E-49 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF52777 2733 2907 2.11E-33 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF47336 504 613 3.53E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1213 1224 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF56801 4 524 6.28E-151 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF47336 1567 1678 9.03E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SMART SM00823 Phosphopantetheine attachment site 511 580 0.0051 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SMART SM00823 Phosphopantetheine attachment site 2637 2706 0.0024 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SMART SM00823 Phosphopantetheine attachment site 1574 1645 6.8E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.30.300.30 2527 2642 1.4E-34 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.30.300.30 401 516 1.3E-37 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.30.300.30 1464 1579 4.5E-36 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:1.10.1200.10 517 579 6.7E-22 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:1.10.1200.10 2643 2706 9.0E-20 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:1.10.1200.10 1580 1649 2.1E-23 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF52777 787 1050 1.48E-63 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 ProSitePatterns PS00012 Phosphopantetheine attachment site. 535 550 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2272 2283 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1600 1615 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 430 1.2E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2150 2556 3.6E-121 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1093 1493 7.6E-131 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00550 Phosphopantetheine attachment site 513 572 2.6E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00550 Phosphopantetheine attachment site 1576 1637 6.3E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00550 Phosphopantetheine attachment site 2639 2702 3.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.40.50.980 156 313 2.2E-32 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.40.50.980 1218 1376 3.1E-30 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.40.50.980 2278 2439 8.4E-34 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00501 AMP-binding enzyme 2130 2532 3.3E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00501 AMP-binding enzyme 1072 1469 6.7E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Pfam PF00501 AMP-binding enzyme 10 406 1.0E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF52777 602 779 7.45E-48 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.40.50.980 1065 1217 5.2E-49 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 SUPERFAMILY SSF56801 1021 1586 1.96E-148 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.30.559.10 580 785 2.5E-42 T 29-03-2018 A616_RS28670 269ad13468ed3e7574d62efbc49a17bf 3188 Gene3D G3DSA:3.30.559.10 1650 1850 2.8E-44 T 29-03-2018 A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 SUPERFAMILY SSF46785 10 82 1.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 2.7E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 SMART SM00345 19 78 1.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 Pfam PF00155 Aminotransferase class I and II 114 434 9.2E-15 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 Gene3D G3DSA:3.90.1150.10 372 470 3.4E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 Gene3D G3DSA:1.10.10.10 6 80 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 SUPERFAMILY SSF53383 73 469 2.71E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS27710 d424b12c7fb49a0fdb610a4b9b3bfccd 473 Gene3D G3DSA:3.40.640.10 129 371 2.3E-27 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 Gene3D G3DSA:3.40.190.10 176 275 3.9E-17 T 29-03-2018 A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 Gene3D G3DSA:3.40.190.10 29 175 5.5E-37 T 29-03-2018 A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 SMART SM00079 53 271 0.0054 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 54 271 5.9E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 SMART SM00062 53 272 8.1E-78 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 SUPERFAMILY SSF53850 1 273 6.52E-69 T 29-03-2018 A616_RS23800 46c60f3d3d170b009da2296b495f70a5 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 76 89 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A616_RS26030 5921b57540e19935ed52c16707539b14 205 Pfam PF11667 Putative zincin peptidase 85 188 1.1E-19 T 29-03-2018 IPR021683 Putative zincin peptidase A616_RS24730 2a1ccdac62c1a5a1b5c9681a39e8e1b4 310 Gene3D G3DSA:3.10.180.10 1 144 2.0E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24730 2a1ccdac62c1a5a1b5c9681a39e8e1b4 310 Gene3D G3DSA:3.10.180.10 145 309 4.9E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24730 2a1ccdac62c1a5a1b5c9681a39e8e1b4 310 SUPERFAMILY SSF54593 1 280 1.94E-45 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24730 2a1ccdac62c1a5a1b5c9681a39e8e1b4 310 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 264 3.4E-34 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 SUPERFAMILY SSF52540 3 246 3.04E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 Gene3D G3DSA:2.40.50.100 277 348 8.8E-5 T 29-03-2018 A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 Pfam PF12857 TOBE-like domain 293 347 5.0E-17 T 29-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 SUPERFAMILY SSF50331 240 354 1.45E-10 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 Pfam PF00005 ABC transporter 18 164 3.8E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 8.7E-117 T 29-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 Gene3D G3DSA:3.40.50.300 1 248 8.9E-81 T 29-03-2018 A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14220 1b09fe1659bc3d704d70882da8ee687f 373 SMART SM00382 27 214 1.5E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 Gene3D G3DSA:1.20.120.220 71 264 8.3E-35 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 PRINTS PR00123 ATP synthase A subunit signature 80 96 5.5E-5 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 PRINTS PR00123 ATP synthase A subunit signature 243 258 5.5E-5 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 14 258 4.4E-32 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 SUPERFAMILY SSF81336 142 257 1.96E-25 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 Pfam PF00119 ATP synthase A chain 21 257 2.9E-46 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29930 c22f17143b50c8c7b963b7412e7a3519 264 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 263 12.562 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29045 c493db3924222b8a3fe786578b951332 334 PIRSF PIRSF000149 1 333 2.7E-143 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 Gene3D G3DSA:3.30.360.10 161 314 8.0E-74 T 29-03-2018 A616_RS29045 c493db3924222b8a3fe786578b951332 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 1.2E-72 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 1.0E-141 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 SUPERFAMILY SSF51735 2 167 6.3E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS29045 c493db3924222b8a3fe786578b951332 334 Gene3D G3DSA:3.40.50.720 1 160 3.2E-80 T 29-03-2018 A616_RS29045 c493db3924222b8a3fe786578b951332 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 SUPERFAMILY SSF55347 151 313 2.06E-76 T 29-03-2018 A616_RS29045 c493db3924222b8a3fe786578b951332 334 SMART SM00846 2 151 1.5E-98 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 101 4.8E-41 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 6.9E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 6.9E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 6.9E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 6.9E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29045 c493db3924222b8a3fe786578b951332 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 6.9E-45 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 7.2E-25 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 7.2E-25 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 7.2E-25 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 Pfam PF01313 Bacterial export proteins, family 3 7 77 6.3E-30 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 6.8E-32 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 PIRSF PIRSF004669 1 89 3.6E-34 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A616_RS19960 a9ff01abe7f8b61d127813aededa8f2d 89 TIGRFAM TIGR01403 fliQ_rel_III: type III secretion protein, HrpO family 6 84 3.5E-23 T 29-03-2018 IPR006306 Type III secretion protein HrpO GO:0006810|GO:0016021 A616_RS02325 962fb3efce59c9f0e0bf38fcbe374af0 554 Gene3D G3DSA:2.60.40.1630 123 266 1.4E-20 T 29-03-2018 A616_RS02325 962fb3efce59c9f0e0bf38fcbe374af0 554 Gene3D G3DSA:2.60.40.1640 469 554 3.5E-6 T 29-03-2018 A616_RS02325 962fb3efce59c9f0e0bf38fcbe374af0 554 Gene3D G3DSA:2.60.40.1640 271 460 7.5E-13 T 29-03-2018 A616_RS02325 962fb3efce59c9f0e0bf38fcbe374af0 554 Pfam PF13786 Domain of unknown function (DUF4179) 95 179 1.2E-14 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS20905 6b36264ac981fcd9f833550da439d651 271 Gene3D G3DSA:3.10.180.10 165 256 2.2E-5 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS20905 6b36264ac981fcd9f833550da439d651 271 Gene3D G3DSA:3.10.180.10 3 140 2.8E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS20905 6b36264ac981fcd9f833550da439d651 271 Pfam PF13468 Glyoxalase-like domain 5 195 4.5E-46 T 29-03-2018 IPR025870 Glyoxalase-like domain A616_RS20905 6b36264ac981fcd9f833550da439d651 271 SUPERFAMILY SSF54593 8 220 5.37E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 SUPERFAMILY SSF158472 185 235 1.57E-11 T 29-03-2018 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 457 4.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 SUPERFAMILY SSF47384 221 303 2.35E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 Gene3D G3DSA:3.30.565.10 310 460 4.8E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 412 1.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 1.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 1.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 1.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 SMART SM00388 238 304 1.5E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 Gene3D G3DSA:1.10.287.130 228 299 4.5E-18 T 29-03-2018 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 SMART SM00304 185 237 7.3E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 2.8E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 Pfam PF00672 HAMP domain 185 233 2.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 SMART SM00387 348 459 1.1E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01970 c1cbaa7b01637537cd234c9a0bffb950 463 SUPERFAMILY SSF55874 294 457 1.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 SUPERFAMILY SSF52172 4 136 4.13E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 Gene3D G3DSA:1.10.10.10 142 238 7.4E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 Pfam PF00072 Response regulator receiver domain 8 119 1.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 PIRSF PIRSF006171 4 236 7.2E-75 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 Pfam PF12431 Transcriptional regulator 135 169 6.7E-10 T 29-03-2018 IPR028141 Transcriptional regulator A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 SUPERFAMILY SSF46785 183 234 1.36E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 Gene3D G3DSA:3.40.50.2300 1 141 6.4E-34 T 29-03-2018 A616_RS07045 8956c43db93b6fe9f40cc71157e00a73 239 SMART SM00448 6 119 1.6E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS20340 45f689cbed9a5c5d618478cd75c5b1ce 355 SUPERFAMILY SSF50156 142 224 4.34E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS20340 45f689cbed9a5c5d618478cd75c5b1ce 355 SUPERFAMILY SSF54211 241 347 1.37E-20 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS20340 45f689cbed9a5c5d618478cd75c5b1ce 355 SMART SM00228 133 200 8.2E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS20340 45f689cbed9a5c5d618478cd75c5b1ce 355 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 244 345 2.3E-10 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A616_RS20340 45f689cbed9a5c5d618478cd75c5b1ce 355 Gene3D G3DSA:3.30.230.10 60 355 2.1E-40 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS20340 45f689cbed9a5c5d618478cd75c5b1ce 355 Pfam PF13180 PDZ domain 136 209 1.2E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 SUPERFAMILY SSF51735 4 246 2.79E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 Gene3D G3DSA:3.40.50.720 1 40 2.2E-10 T 29-03-2018 A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 Gene3D G3DSA:3.40.50.720 41 247 1.7E-66 T 29-03-2018 A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 7.1E-73 T 29-03-2018 A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.4E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.4E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.4E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.4E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.4E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 7.4E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS06635 9ae34be15a71310d79c539a9172eb034 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS11805 fb6b4ef712b971cbbb7ea91121b09849 514 Pfam PF13556 PucR C-terminal helix-turn-helix domain 444 501 3.8E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS11805 fb6b4ef712b971cbbb7ea91121b09849 514 Gene3D G3DSA:1.10.10.60 427 482 4.9E-5 T 29-03-2018 A616_RS11805 fb6b4ef712b971cbbb7ea91121b09849 514 Pfam PF07905 Purine catabolism regulatory protein-like family 7 126 1.1E-31 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain A616_RS09475 ad4df839daf02812cf97046261ccb298 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 552 2.7E-54 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 24 188 4.2E-56 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 441 460 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 212 346 2.2E-45 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 SUPERFAMILY SSF52518 382 574 1.68E-73 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS09475 ad4df839daf02812cf97046261ccb298 578 Gene3D G3DSA:3.40.50.970 18 212 3.9E-62 T 29-03-2018 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 Gene3D G3DSA:3.40.50.1220 213 365 1.9E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS09475 ad4df839daf02812cf97046261ccb298 578 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 24 573 9.1E-248 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 SUPERFAMILY SSF52518 20 200 9.42E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS09475 ad4df839daf02812cf97046261ccb298 578 Gene3D G3DSA:3.40.50.970 366 573 1.0E-56 T 29-03-2018 A616_RS09475 ad4df839daf02812cf97046261ccb298 578 SUPERFAMILY SSF52467 174 377 8.59E-55 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS30755 2093e7fb2824c644568eaa7c048f7d8c 95 SUPERFAMILY SSF143414 5 91 2.49E-30 T 29-03-2018 A616_RS30755 2093e7fb2824c644568eaa7c048f7d8c 95 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 24 43 - T 29-03-2018 IPR020808 Bacterial microcompartments protein, conserved site A616_RS30755 2093e7fb2824c644568eaa7c048f7d8c 95 SMART SM00877 6 82 1.8E-32 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30755 2093e7fb2824c644568eaa7c048f7d8c 95 Pfam PF00936 BMC domain 7 82 2.9E-26 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30755 2093e7fb2824c644568eaa7c048f7d8c 95 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 7 68 1.0E-10 T 29-03-2018 A616_RS19385 46097a910bb84694a263e5c9b72bf01a 400 Gene3D G3DSA:1.10.150.20 281 319 9.2E-5 T 29-03-2018 A616_RS19385 46097a910bb84694a263e5c9b72bf01a 400 Pfam PF01548 Transposase 5 163 5.4E-34 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A616_RS19385 46097a910bb84694a263e5c9b72bf01a 400 Gene3D G3DSA:1.10.150.20 132 280 0.02 T 29-03-2018 A616_RS19385 46097a910bb84694a263e5c9b72bf01a 400 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 361 8.0E-28 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A616_RS08080 ad6960ad029b0911e1c40f52b77aa4a0 202 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 4.9E-63 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A616_RS08080 ad6960ad029b0911e1c40f52b77aa4a0 202 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 30.143 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A616_RS08080 ad6960ad029b0911e1c40f52b77aa4a0 202 Gene3D G3DSA:3.40.50.300 1 202 2.9E-48 T 29-03-2018 A616_RS08080 ad6960ad029b0911e1c40f52b77aa4a0 202 SUPERFAMILY SSF52540 1 197 1.26E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08080 ad6960ad029b0911e1c40f52b77aa4a0 202 Pfam PF01121 Dephospho-CoA kinase 3 182 4.8E-63 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A616_RS13965 0759403d4525639133942447e079a31a 469 Gene3D G3DSA:1.25.40.10 367 468 1.8E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 Gene3D G3DSA:1.25.40.10 2 156 9.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 Gene3D G3DSA:1.25.40.10 281 333 8.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SMART SM00028 410 443 4.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SMART SM00028 272 305 52.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SMART SM00028 167 200 0.45 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SMART SM00028 96 129 26.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SMART SM00028 201 234 73.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SMART SM00028 340 373 340.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 Pfam PF14559 Tetratricopeptide repeat 178 240 1.0E-7 T 29-03-2018 A616_RS13965 0759403d4525639133942447e079a31a 469 Gene3D G3DSA:1.25.40.10 164 210 9.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 Gene3D G3DSA:1.10.150.200 211 280 0.0037 T 29-03-2018 A616_RS13965 0759403d4525639133942447e079a31a 469 SUPERFAMILY SSF48452 85 154 6.13E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 Gene3D G3DSA:1.25.40.10 334 366 1.4E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 SUPERFAMILY SSF48452 337 459 3.25E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13965 0759403d4525639133942447e079a31a 469 Pfam PF13432 Tetratricopeptide repeat 383 440 6.1E-4 T 29-03-2018 A616_RS13965 0759403d4525639133942447e079a31a 469 SUPERFAMILY SSF48452 170 373 2.28E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 SUPERFAMILY SSF52540 2 138 1.22E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 169 182 - T 29-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 Gene3D G3DSA:3.30.60.20 138 190 4.4E-16 T 29-03-2018 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 Gene3D G3DSA:3.40.50.300 2 137 1.5E-41 T 29-03-2018 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 Hamap MF_00124 Thymidine kinase [tdk]. 1 185 32.145 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 SUPERFAMILY SSF57716 138 187 3.53E-12 T 29-03-2018 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 PIRSF PIRSF035805 1 191 2.0E-54 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS16460 5659d46d0183cc66ef4330b2144aafa8 191 Pfam PF00265 Thymidine kinase 3 182 4.5E-46 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A616_RS29300 e2591975927bdfaf139c1f6d6eb2da9f 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.7E-88 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 A616_RS29300 e2591975927bdfaf139c1f6d6eb2da9f 228 Pfam PF00005 ABC transporter 18 165 3.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS29300 e2591975927bdfaf139c1f6d6eb2da9f 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29300 e2591975927bdfaf139c1f6d6eb2da9f 228 SMART SM00382 27 214 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS29300 e2591975927bdfaf139c1f6d6eb2da9f 228 SUPERFAMILY SSF52540 1 222 3.59E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29300 e2591975927bdfaf139c1f6d6eb2da9f 228 Gene3D G3DSA:3.40.50.300 1 226 1.8E-64 T 29-03-2018 A616_RS25595 394ad65482a82dcb728ef9f25a000373 547 Gene3D G3DSA:3.10.105.10 321 518 3.9E-47 T 29-03-2018 A616_RS25595 394ad65482a82dcb728ef9f25a000373 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 465 3.1E-78 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS25595 394ad65482a82dcb728ef9f25a000373 547 Gene3D G3DSA:3.90.76.10 75 185 1.1E-30 T 29-03-2018 A616_RS25595 394ad65482a82dcb728ef9f25a000373 547 Gene3D G3DSA:3.40.190.10 186 320 1.9E-37 T 29-03-2018 A616_RS25595 394ad65482a82dcb728ef9f25a000373 547 SUPERFAMILY SSF53850 47 541 3.26E-121 T 29-03-2018 A616_RS25595 394ad65482a82dcb728ef9f25a000373 547 PIRSF PIRSF002741 5 547 1.8E-115 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS00665 795b67c02b3d3768b1807a98f65c490a 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 124 2.5E-52 T 29-03-2018 IPR006056 RidA family A616_RS00665 795b67c02b3d3768b1807a98f65c490a 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 121 - T 29-03-2018 IPR019897 RidA, conserved site A616_RS00665 795b67c02b3d3768b1807a98f65c490a 126 SUPERFAMILY SSF55298 2 125 1.05E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS00665 795b67c02b3d3768b1807a98f65c490a 126 Pfam PF01042 Endoribonuclease L-PSP 9 124 3.5E-45 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family A616_RS00665 795b67c02b3d3768b1807a98f65c490a 126 Gene3D G3DSA:3.30.1330.40 2 126 9.7E-49 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS22800 ddc3eb807376de85d5c80fe284011791 244 Gene3D G3DSA:1.10.10.10 9 186 2.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22800 ddc3eb807376de85d5c80fe284011791 244 SUPERFAMILY SSF46785 6 110 4.55E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22800 ddc3eb807376de85d5c80fe284011791 244 SMART SM00418 11 97 2.5E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS22800 ddc3eb807376de85d5c80fe284011791 244 Pfam PF12840 Helix-turn-helix domain 11 68 8.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22800 ddc3eb807376de85d5c80fe284011791 244 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 6.5E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS22800 ddc3eb807376de85d5c80fe284011791 244 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 6.5E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 Gene3D G3DSA:3.40.190.10 88 175 5.3E-17 T 29-03-2018 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 SUPERFAMILY SSF46785 1 84 3.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 Pfam PF03466 LysR substrate binding domain 90 291 1.6E-42 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 SUPERFAMILY SSF53850 90 293 1.71E-39 T 29-03-2018 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 Gene3D G3DSA:1.10.10.10 1 83 1.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.0E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 Gene3D G3DSA:3.40.190.10 176 257 3.6E-22 T 29-03-2018 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS21995 565f4abc87c928f21440c7c1176dae98 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15565 03ea8a7d86508490aa8d968ff5e2319c 467 Gene3D G3DSA:2.60.120.600 298 467 2.5E-60 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 A616_RS15565 03ea8a7d86508490aa8d968ff5e2319c 467 Pfam PF06742 Protein of unknown function (DUF1214) 343 450 5.4E-40 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 A616_RS15565 03ea8a7d86508490aa8d968ff5e2319c 467 Pfam PF06863 Protein of unknown function (DUF1254) 84 213 1.2E-48 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 A616_RS15565 03ea8a7d86508490aa8d968ff5e2319c 467 SUPERFAMILY SSF160935 47 466 2.22E-131 T 29-03-2018 A616_RS15565 03ea8a7d86508490aa8d968ff5e2319c 467 Gene3D G3DSA:2.60.40.1610 83 228 9.3E-49 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 A616_RS14995 c96fab33669689cd338c142612e3014a 525 Gene3D G3DSA:3.90.76.10 65 166 4.0E-31 T 29-03-2018 A616_RS14995 c96fab33669689cd338c142612e3014a 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 442 8.4E-105 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS14995 c96fab33669689cd338c142612e3014a 525 PIRSF PIRSF002741 2 524 4.3E-139 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS14995 c96fab33669689cd338c142612e3014a 525 Gene3D G3DSA:3.10.105.10 301 494 8.5E-62 T 29-03-2018 A616_RS14995 c96fab33669689cd338c142612e3014a 525 Gene3D G3DSA:3.40.190.10 167 300 1.2E-50 T 29-03-2018 A616_RS14995 c96fab33669689cd338c142612e3014a 525 SUPERFAMILY SSF53850 44 524 4.96E-158 T 29-03-2018 A616_RS06860 b6b31b062dc6827b3800ebcd96859c48 596 Pfam PF08439 Oligopeptidase F 114 180 5.8E-14 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A616_RS06860 b6b31b062dc6827b3800ebcd96859c48 596 Gene3D G3DSA:1.10.1370.10 370 583 1.0E-10 T 29-03-2018 A616_RS06860 b6b31b062dc6827b3800ebcd96859c48 596 Gene3D G3DSA:1.10.1370.10 81 348 1.6E-7 T 29-03-2018 A616_RS06860 b6b31b062dc6827b3800ebcd96859c48 596 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 8 592 1.7E-207 T 29-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 A616_RS06860 b6b31b062dc6827b3800ebcd96859c48 596 SUPERFAMILY SSF55486 54 593 7.33E-98 T 29-03-2018 A616_RS06860 b6b31b062dc6827b3800ebcd96859c48 596 Pfam PF01432 Peptidase family M3 200 579 4.9E-19 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS09695 325c0ae8f520711321a808f0d4d2b9b3 329 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 93 242 1.1E-43 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS09695 325c0ae8f520711321a808f0d4d2b9b3 329 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 92 243 1.4E-42 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 PIRSF PIRSF001365 1 291 1.1E-85 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 SUPERFAMILY SSF51569 3 285 2.3E-87 T 29-03-2018 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 2.4E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 2.4E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 2.4E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 2.4E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 Pfam PF00701 Dihydrodipicolinate synthetase family 4 283 2.1E-63 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 Gene3D G3DSA:3.20.20.70 1 290 4.9E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS25140 8c3559e02a44f3d802ba3c4b2481ef28 294 SMART SM01130 3 287 1.8E-101 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS16390 1daf4f3be7272a4e6c8c43a199a4095f 433 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 111 129 5.9E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS16390 1daf4f3be7272a4e6c8c43a199a4095f 433 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 42 60 5.9E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS16390 1daf4f3be7272a4e6c8c43a199a4095f 433 SUPERFAMILY SSF52540 13 247 5.22E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16390 1daf4f3be7272a4e6c8c43a199a4095f 433 SMART SM00382 38 176 0.0084 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS16390 1daf4f3be7272a4e6c8c43a199a4095f 433 Gene3D G3DSA:3.40.50.300 9 190 1.4E-20 T 29-03-2018 A616_RS16390 1daf4f3be7272a4e6c8c43a199a4095f 433 Pfam PF07728 AAA domain (dynein-related subfamily) 42 170 3.8E-25 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 SUPERFAMILY SSF53383 118 492 3.52E-77 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 Gene3D G3DSA:1.10.10.10 3 78 5.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 Gene3D G3DSA:3.40.640.10 143 397 1.7E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 SUPERFAMILY SSF46785 7 79 1.65E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 SMART SM00345 17 76 1.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 Gene3D G3DSA:3.90.1150.10 398 493 6.2E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS15890 f9df7307131c931e6f045cdf16d884ac 496 Pfam PF00155 Aminotransferase class I and II 142 485 2.1E-28 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS11205 44a96ec9f807877a3254a74225064868 174 Gene3D G3DSA:3.40.50.1000 43 158 3.0E-22 T 29-03-2018 IPR023214 HAD-like domain A616_RS11205 44a96ec9f807877a3254a74225064868 174 Gene3D G3DSA:3.40.50.1000 12 42 0.001 T 29-03-2018 IPR023214 HAD-like domain A616_RS11205 44a96ec9f807877a3254a74225064868 174 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 6 165 4.7E-52 T 29-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like A616_RS11205 44a96ec9f807877a3254a74225064868 174 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 137 9.3E-11 T 29-03-2018 IPR023214 HAD-like domain A616_RS11205 44a96ec9f807877a3254a74225064868 174 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 4.1E-25 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A616_RS11205 44a96ec9f807877a3254a74225064868 174 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 34 137 8.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS11205 44a96ec9f807877a3254a74225064868 174 SUPERFAMILY SSF56784 4 151 1.25E-26 T 29-03-2018 IPR023214 HAD-like domain A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 Gene3D G3DSA:3.20.20.70 166 355 2.6E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 Pfam PF01595 Domain of unknown function DUF21 11 206 1.9E-51 T 29-03-2018 IPR002550 Domain of unknown function DUF21 A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 SUPERFAMILY SSF54631 216 359 1.16E-31 T 29-03-2018 A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 SUPERFAMILY SSF56176 358 438 7.36E-18 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 Pfam PF03471 Transporter associated domain 358 431 5.6E-16 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 Gene3D G3DSA:3.30.465.10 356 434 2.0E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 SMART SM00116 230 279 4.6 T 29-03-2018 IPR000644 CBS domain A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 SMART SM00116 292 340 0.011 T 29-03-2018 IPR000644 CBS domain A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 Pfam PF00571 CBS domain 227 273 0.002 T 29-03-2018 IPR000644 CBS domain A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 Pfam PF00571 CBS domain 291 340 6.7E-9 T 29-03-2018 IPR000644 CBS domain A616_RS05040 bde7e4201df398a2feebc9adb59c2135 445 SMART SM01091 354 432 3.8E-21 T 29-03-2018 IPR005170 Transporter-associated domain A616_RS12110 5a534fcbe506c753dd12deda19cf2002 308 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 3 297 9.6E-72 T 29-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 A616_RS12110 5a534fcbe506c753dd12deda19cf2002 308 SUPERFAMILY SSF51658 81 287 2.35E-19 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS12110 5a534fcbe506c753dd12deda19cf2002 308 Gene3D G3DSA:3.20.20.150 56 305 4.5E-26 T 29-03-2018 A616_RS12110 5a534fcbe506c753dd12deda19cf2002 308 Pfam PF03851 UV-endonuclease UvdE 4 269 2.3E-80 T 29-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 SUPERFAMILY SSF64518 1 273 5.62E-85 T 29-03-2018 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 PRINTS PR00207 Flagellin signature 35 52 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 PRINTS PR00207 Flagellin signature 74 93 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 PRINTS PR00207 Flagellin signature 110 133 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 Gene3D G3DSA:1.20.1330.10 38 245 1.8E-67 T 29-03-2018 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 4.4E-42 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS29550 f36d38f47bcc0f8411bd0f1bcd59bfc4 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 188 272 3.5E-29 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 Gene3D G3DSA:3.40.50.980 4 197 5.8E-40 T 29-03-2018 A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 Pfam PF00501 AMP-binding enzyme 13 443 2.8E-110 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 Gene3D G3DSA:2.30.38.10 352 436 4.3E-27 T 29-03-2018 A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 Gene3D G3DSA:3.30.300.30 438 541 8.7E-30 T 29-03-2018 A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 527 1.4E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 Gene3D G3DSA:3.40.50.980 198 351 1.1E-50 T 29-03-2018 A616_RS14095 c9d732ed3d5aa2a6c92b62b05fb87dd8 552 SUPERFAMILY SSF56801 4 540 7.85E-156 T 29-03-2018 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 Gene3D G3DSA:3.40.50.300 489 812 8.1E-54 T 29-03-2018 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 SUPERFAMILY SSF52540 293 475 3.51E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 SUPERFAMILY SSF52540 5 109 3.51E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 133 801 1.2E-225 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 Gene3D G3DSA:3.40.50.300 13 90 2.8E-8 T 29-03-2018 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 Gene3D G3DSA:1.20.1580.10 91 371 1.7E-58 T 29-03-2018 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 SMART SM00382 513 784 0.27 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 SMART SM00382 24 448 0.0077 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 Pfam PF00005 ABC transporter 504 736 3.0E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 Pfam PF00005 ABC transporter 15 49 3.3E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 ProSitePatterns PS00211 ABC transporters family signature. 371 385 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS23165 db009b2dbe43db8e3a56576dc88a3424 813 SUPERFAMILY SSF52540 494 789 7.94E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Gene3D G3DSA:1.10.287.380 816 886 9.8E-24 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Gene3D G3DSA:1.10.730.10 528 756 5.6E-84 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 65 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 TIGRFAM TIGR00422 valS: valine--tRNA ligase 14 870 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 1.1E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 47 58 1.1E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 356 369 1.1E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 455 476 1.1E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 PRINTS PR00986 Valyl-tRNA synthetase signature 241 258 1.1E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 SUPERFAMILY SSF50677 201 352 2.88E-63 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 823 888 2.3E-20 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Gene3D G3DSA:3.40.50.620 42 298 4.3E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Gene3D G3DSA:3.40.50.620 299 527 3.0E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 572 6.5E-218 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 SUPERFAMILY SSF52374 351 584 1.4E-146 T 29-03-2018 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 SUPERFAMILY SSF52374 13 203 1.4E-146 T 29-03-2018 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 SUPERFAMILY SSF47323 586 836 2.06E-76 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Hamap MF_02004 Valine--tRNA ligase [valS]. 13 888 15.946 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 Pfam PF08264 Anticodon-binding domain of tRNA 617 763 1.2E-43 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A616_RS10445 4acb931d1a1c53bd06db4e737b7eec3c 890 SUPERFAMILY SSF46589 823 887 6.28E-16 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 SMART SM00382 33 233 1.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 Gene3D G3DSA:3.40.50.300 1 329 1.6E-83 T 29-03-2018 A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 SUPERFAMILY SSF52540 4 254 1.16E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 3.7E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 Pfam PF00005 ABC transporter 25 183 2.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS13380 06f2758028be40394b4ed682867a2d8a 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 5.3E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.8E-42 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 2.8E-101 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 2.6E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.6E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 2.6E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 2.6E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 2.6E-51 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 SUPERFAMILY SSF55831 1 264 2.88E-135 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 42.392 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 Pfam PF00303 Thymidylate synthase 2 264 3.9E-131 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS24145 024a83f3ad61f97d672a883049a273b7 264 Gene3D G3DSA:3.30.572.10 1 264 3.3E-138 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 Gene3D G3DSA:3.40.50.1000 2 255 3.4E-42 T 29-03-2018 IPR023214 HAD-like domain A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 SUPERFAMILY SSF56784 3 254 1.19E-66 T 29-03-2018 IPR023214 HAD-like domain A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 249 2.2E-58 T 29-03-2018 IPR000150 Cof family GO:0016787 A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 223 9.2E-26 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 248 5.1E-59 T 29-03-2018 IPR023214 HAD-like domain A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 ProSitePatterns PS01229 Hypothetical cof family signature 2. 204 226 - T 29-03-2018 A616_RS11935 f0a5c89e247a440b819c00e74d072285 256 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 29-03-2018 A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 SUPERFAMILY SSF53795 132 297 6.1E-39 T 29-03-2018 A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 Pfam PF02603 HPr Serine kinase N terminus 5 127 6.1E-38 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 40.505 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 Gene3D G3DSA:3.40.1390.20 3 132 2.0E-41 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 2.3E-74 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 5 302 2.8E-120 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 SUPERFAMILY SSF75138 5 131 5.89E-36 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A616_RS29245 18e0ceb47ee07c2965a1606f48958482 311 Gene3D G3DSA:3.40.50.300 134 307 3.4E-43 T 29-03-2018 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 SUPERFAMILY SSF101790 275 364 1.31E-27 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Gene3D G3DSA:4.10.1250.10 239 280 5.4E-15 T 29-03-2018 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Gene3D G3DSA:3.30.1360.120 125 237 2.3E-32 T 29-03-2018 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Gene3D G3DSA:3.30.1360.120 4 124 3.6E-33 T 29-03-2018 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Gene3D G3DSA:2.40.30.110 283 367 4.0E-27 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 358 5.2E-28 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 364 4.4E-143 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 260 5.1E-96 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 SUPERFAMILY SSF103025 3 283 4.71E-104 T 29-03-2018 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 PIRSF PIRSF006487 1 367 5.1E-103 T 29-03-2018 A616_RS12925 47e589e40f7f95696f8bd58221fc73bf 367 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 364 49.095 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A616_RS16210 b41bb012af9cbaf221b129f409228ca8 178 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 8 166 2.3E-72 T 29-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 A616_RS16210 b41bb012af9cbaf221b129f409228ca8 178 Gene3D G3DSA:2.60.120.10 8 173 1.5E-43 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS16210 b41bb012af9cbaf221b129f409228ca8 178 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 3 171 33.689 T 29-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 A616_RS16210 b41bb012af9cbaf221b129f409228ca8 178 SUPERFAMILY SSF51182 2 169 2.01E-50 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS16210 b41bb012af9cbaf221b129f409228ca8 178 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 1 152 1.1E-51 T 29-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 A616_RS19425 33ff595efb2a6567120220f34862704e 136 Gene3D G3DSA:1.10.1660.10 8 65 4.5E-19 T 29-03-2018 A616_RS19425 33ff595efb2a6567120220f34862704e 136 SMART SM00422 12 80 1.1E-26 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS19425 33ff595efb2a6567120220f34862704e 136 Pfam PF13411 MerR HTH family regulatory protein 13 79 7.2E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS19425 33ff595efb2a6567120220f34862704e 136 Gene3D G3DSA:1.10.1660.10 66 135 9.1E-4 T 29-03-2018 A616_RS19425 33ff595efb2a6567120220f34862704e 136 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS19425 33ff595efb2a6567120220f34862704e 136 SUPERFAMILY SSF46955 12 117 7.02E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS27645 c83f05faf5c05968c2c63a80d74ca9c4 327 Gene3D G3DSA:3.40.50.300 24 193 7.4E-29 T 29-03-2018 A616_RS27645 c83f05faf5c05968c2c63a80d74ca9c4 327 SMART SM00382 40 184 1.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27645 c83f05faf5c05968c2c63a80d74ca9c4 327 Gene3D G3DSA:1.10.8.300 206 322 9.6E-28 T 29-03-2018 A616_RS27645 c83f05faf5c05968c2c63a80d74ca9c4 327 PIRSF PIRSF002849 1 327 1.3E-121 T 29-03-2018 A616_RS27645 c83f05faf5c05968c2c63a80d74ca9c4 327 SUPERFAMILY SSF52540 5 297 1.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27645 c83f05faf5c05968c2c63a80d74ca9c4 327 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 176 4.9E-63 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A616_RS29795 1ef6ed31dc3477ee5a4525ee2c638a85 322 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site A616_RS29795 1ef6ed31dc3477ee5a4525ee2c638a85 322 SUPERFAMILY SSF117143 136 257 3.14E-11 T 29-03-2018 A616_RS29795 1ef6ed31dc3477ee5a4525ee2c638a85 322 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 253 315 4.3E-15 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A616_RS29795 1ef6ed31dc3477ee5a4525ee2c638a85 322 Pfam PF00460 Flagella basal body rod protein 5 35 4.8E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 403 473 8.4E-10 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 370 9.1E-107 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 SUPERFAMILY SSF55904 341 484 1.15E-36 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 Gene3D G3DSA:3.40.640.10 6 284 7.7E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 Gene3D G3DSA:3.90.100.10 403 485 2.4E-27 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 Gene3D G3DSA:3.90.1150.10 312 402 2.9E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS28565 9bc142dd1325bd1538d3a20a3b7fa987 485 SUPERFAMILY SSF53383 6 382 5.51E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS01005 e099f21c0149ea628f59637451c73bb6 292 SUPERFAMILY SSF52540 52 234 2.92E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01005 e099f21c0149ea628f59637451c73bb6 292 Gene3D G3DSA:3.40.50.300 52 283 1.1E-6 T 29-03-2018 A616_RS27640 643186be9af45c733ab380be9b51796c 293 Gene3D G3DSA:3.40.50.410 53 242 9.4E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27640 643186be9af45c733ab380be9b51796c 293 Pfam PF01882 Protein of unknown function DUF58 42 116 1.5E-18 T 29-03-2018 IPR002881 Domain of unknown function DUF58 A616_RS27640 643186be9af45c733ab380be9b51796c 293 SUPERFAMILY SSF53300 77 204 2.5E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 Pfam PF04542 Sigma-70 region 2 39 87 4.8E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 Pfam PF04545 Sigma-70, region 4 138 179 2.3E-8 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 180 4.7E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 SUPERFAMILY SSF88659 105 180 8.72E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 SUPERFAMILY SSF88946 35 94 9.1E-10 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 Gene3D G3DSA:1.10.10.10 105 184 6.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03820 7d1abb77448c672285876aa90edc7a6f 184 Gene3D G3DSA:1.10.1740.10 16 86 4.0E-11 T 29-03-2018 A616_RS04435 736724a3b9392001803962d1aa75db09 251 Gene3D G3DSA:3.60.21.10 5 248 2.8E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS04435 736724a3b9392001803962d1aa75db09 251 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 10 187 1.7E-24 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A616_RS04435 736724a3b9392001803962d1aa75db09 251 PIRSF PIRSF000883 8 250 3.7E-49 T 29-03-2018 IPR011152 Phosphoesterase MJ0912 A616_RS04435 736724a3b9392001803962d1aa75db09 251 SUPERFAMILY SSF56300 10 241 4.09E-43 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS28635 14b19efe22a34697edfdcef258772d50 418 Gene3D G3DSA:3.30.1490.20 115 190 6.6E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS28635 14b19efe22a34697edfdcef258772d50 418 SUPERFAMILY SSF56059 95 321 2.65E-38 T 29-03-2018 A616_RS28635 14b19efe22a34697edfdcef258772d50 418 Gene3D G3DSA:3.40.50.20 10 114 2.0E-9 T 29-03-2018 A616_RS28635 14b19efe22a34697edfdcef258772d50 418 Pfam PF13535 ATP-grasp domain 145 293 3.3E-24 T 29-03-2018 A616_RS28635 14b19efe22a34697edfdcef258772d50 418 Gene3D G3DSA:3.30.470.20 191 402 1.2E-25 T 29-03-2018 A616_RS02470 0b0bcb26678c55caf1b06be8bcb5113d 252 Pfam PF12706 Beta-lactamase superfamily domain 20 214 7.9E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02470 0b0bcb26678c55caf1b06be8bcb5113d 252 Gene3D G3DSA:3.60.15.10 1 252 1.1E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02470 0b0bcb26678c55caf1b06be8bcb5113d 252 SUPERFAMILY SSF56281 1 250 2.8E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Pfam PF01807 CHC2 zinc finger 6 99 1.1E-37 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Gene3D G3DSA:1.20.50.20 375 426 7.0E-7 T 29-03-2018 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Pfam PF08275 DNA primase catalytic core, N-terminal domain 130 260 3.4E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Gene3D G3DSA:3.40.1360.10 249 371 2.3E-34 T 29-03-2018 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Gene3D G3DSA:3.90.980.10 107 248 4.6E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 TIGRFAM TIGR01391 dnaG: DNA primase 6 424 1.3E-145 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 SUPERFAMILY SSF57783 6 101 5.61E-36 T 29-03-2018 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Gene3D G3DSA:3.90.580.10 1 103 1.8E-35 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 SMART SM00400 36 90 9.1E-32 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Gene3D G3DSA:1.10.860.10 475 571 3.0E-11 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 PIRSF PIRSF002811 3 610 1.2E-178 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 SUPERFAMILY SSF56731 115 427 1.7E-99 T 29-03-2018 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 SUPERFAMILY SSF48024 471 573 1.14E-5 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Pfam PF10410 DnaB-helicase binding domain of primase 377 428 1.1E-10 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Pfam PF13155 Toprim-like 271 355 3.3E-21 T 29-03-2018 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 Hamap MF_00974 DNA primase [dnaG]. 4 608 28.884 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A616_RS11685 ae59989f42bbdb1796807d0f72c97d6f 624 SMART SM00493 267 338 1.7E-11 T 29-03-2018 IPR006171 TOPRIM domain A616_RS26295 65497c736b14e729208cae3ed87451f2 127 Gene3D G3DSA:2.60.40.420 22 127 1.3E-13 T 29-03-2018 IPR008972 Cupredoxin A616_RS26295 65497c736b14e729208cae3ed87451f2 127 Pfam PF13473 Cupredoxin-like domain 35 121 2.3E-8 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain A616_RS26295 65497c736b14e729208cae3ed87451f2 127 SUPERFAMILY SSF49503 44 127 9.91E-16 T 29-03-2018 IPR008972 Cupredoxin A616_RS05980 3d74b8ef48e8b90f3913d3f6f5a67914 253 Pfam PF13649 Methyltransferase domain 36 133 2.5E-19 T 29-03-2018 A616_RS05980 3d74b8ef48e8b90f3913d3f6f5a67914 253 SUPERFAMILY SSF53335 6 250 3.06E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS05980 3d74b8ef48e8b90f3913d3f6f5a67914 253 Gene3D G3DSA:3.40.50.150 4 253 3.6E-30 T 29-03-2018 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 Gene3D G3DSA:1.10.274.10 25 131 2.8E-34 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 2.8E-27 T 29-03-2018 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 2.8E-27 T 29-03-2018 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 2.8E-27 T 29-03-2018 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 2.8E-27 T 29-03-2018 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 225 7.4E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 Gene3D G3DSA:3.50.30.10 132 254 7.0E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 SUPERFAMILY SSF47831 32 143 4.45E-32 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 254 540 1.3E-113 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 183 194 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 SUPERFAMILY SSF51621 249 549 1.57E-107 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 SUPERFAMILY SSF52009 111 232 3.27E-32 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 Gene3D G3DSA:3.20.20.60 255 569 1.3E-99 T 29-03-2018 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 PIRSF PIRSF000732 1 569 3.3E-212 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 3 126 1.1E-30 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A616_RS00365 53ab7adaafeb14a34a3dbf856ea26328 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 566 1.1E-195 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A616_RS17330 6a3213bc2bcdd49a48278c7bcb34ab1d 106 SUPERFAMILY SSF47729 1 106 1.77E-25 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A616_RS17330 6a3213bc2bcdd49a48278c7bcb34ab1d 106 Pfam PF00216 Bacterial DNA-binding protein 1 64 7.6E-24 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS17330 6a3213bc2bcdd49a48278c7bcb34ab1d 106 SMART SM00411 1 106 2.2E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS17330 6a3213bc2bcdd49a48278c7bcb34ab1d 106 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.9E-6 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS17330 6a3213bc2bcdd49a48278c7bcb34ab1d 106 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.9E-6 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS17330 6a3213bc2bcdd49a48278c7bcb34ab1d 106 Gene3D G3DSA:4.10.520.10 1 106 3.4E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A616_RS31305 c555ff3203bf520d09d51f7972ca5a7d 316 Pfam PF02450 Lecithin:cholesterol acyltransferase 40 142 4.1E-12 T 29-03-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 A616_RS31305 c555ff3203bf520d09d51f7972ca5a7d 316 Gene3D G3DSA:3.40.50.1820 4 303 1.2E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS31305 c555ff3203bf520d09d51f7972ca5a7d 316 SUPERFAMILY SSF53474 7 161 1.64E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 Gene3D G3DSA:3.40.50.300 1 328 1.5E-80 T 29-03-2018 A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 SUPERFAMILY SSF52540 32 306 5.21E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 7.9E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 Pfam PF00005 ABC transporter 25 181 2.4E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 1.7E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28375 eb858d0106f0143b5e220ac37ceab91c 329 SMART SM00382 33 239 6.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 503 628 2.1E-29 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 Gene3D G3DSA:1.10.8.60 635 698 0.11 T 29-03-2018 A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 Gene3D G3DSA:3.40.50.300 433 634 3.0E-32 T 29-03-2018 A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 SUPERFAMILY SSF52540 225 431 3.27E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 SMART SM00382 251 386 5.9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 SMART SM00382 499 631 4.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 SUPERFAMILY SSF52540 454 687 4.55E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23275 e3bb2f43b26baf4298cfa58a6458473b 718 Gene3D G3DSA:3.40.50.300 151 432 2.7E-6 T 29-03-2018 A616_RS32230 2336cd9a60e747f81a3817f9ce816a80 201 SUPERFAMILY SSF53163 18 197 8.37E-51 T 29-03-2018 IPR023430 Peptidase HybD-like domain A616_RS32230 2336cd9a60e747f81a3817f9ce816a80 201 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 44 182 3.7E-64 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 A616_RS32230 2336cd9a60e747f81a3817f9ce816a80 201 Pfam PF06866 Protein of unknown function (DUF1256) 17 180 2.0E-61 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 A616_RS32230 2336cd9a60e747f81a3817f9ce816a80 201 Gene3D G3DSA:3.40.50.1450 14 158 1.7E-32 T 29-03-2018 IPR023430 Peptidase HybD-like domain A616_RS01705 92b0189489ae745eb14756ea13e04825 274 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 119 236 3.8E-44 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS01705 92b0189489ae745eb14756ea13e04825 274 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 10 253 1.6E-89 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 A616_RS01705 92b0189489ae745eb14756ea13e04825 274 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 255 34.177 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 A616_RS01705 92b0189489ae745eb14756ea13e04825 274 SUPERFAMILY SSF143597 40 241 1.83E-68 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS01705 92b0189489ae745eb14756ea13e04825 274 Gene3D G3DSA:3.40.1700.10 112 240 2.9E-38 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS01705 92b0189489ae745eb14756ea13e04825 274 PIRSF PIRSF004793 4 270 4.0E-93 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 A616_RS29510 c5504436c39dc522db4f6f9bc30cb727 393 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 25 385 1.6E-166 T 29-03-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family A616_RS29510 c5504436c39dc522db4f6f9bc30cb727 393 Gene3D G3DSA:3.40.640.10 25 274 3.2E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS29510 c5504436c39dc522db4f6f9bc30cb727 393 PIRSF PIRSF000390 22 392 2.4E-94 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A616_RS29510 c5504436c39dc522db4f6f9bc30cb727 393 SUPERFAMILY SSF53383 24 389 9.08E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS29510 c5504436c39dc522db4f6f9bc30cb727 393 Gene3D G3DSA:3.90.1150.10 275 391 1.7E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29510 c5504436c39dc522db4f6f9bc30cb727 393 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 37 389 5.5E-91 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A616_RS19345 c7f7cd11ae8026c7409cb7bfc3f6c049 404 SUPERFAMILY SSF52266 234 403 1.83E-24 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS19345 c7f7cd11ae8026c7409cb7bfc3f6c049 404 Gene3D G3DSA:3.40.50.1110 214 401 4.3E-21 T 29-03-2018 A616_RS19345 c7f7cd11ae8026c7409cb7bfc3f6c049 404 Gene3D G3DSA:3.40.50.1110 25 213 1.8E-25 T 29-03-2018 A616_RS19345 c7f7cd11ae8026c7409cb7bfc3f6c049 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 257 390 1.3E-15 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS19345 c7f7cd11ae8026c7409cb7bfc3f6c049 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 78 200 1.0E-15 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS19345 c7f7cd11ae8026c7409cb7bfc3f6c049 404 SUPERFAMILY SSF52266 51 214 2.6E-26 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 127 3.7E-10 T 29-03-2018 IPR000014 PAS domain A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 245 260 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 Pfam PF00158 Sigma-54 interaction domain 158 325 1.0E-64 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 371 380 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 SMART SM00091 14 81 9.7E-8 T 29-03-2018 IPR000014 PAS domain A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 182 195 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 Gene3D G3DSA:3.40.50.300 159 330 1.5E-24 T 29-03-2018 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 SUPERFAMILY SSF46689 418 466 5.02E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 Gene3D G3DSA:1.10.8.60 331 401 1.3E-24 T 29-03-2018 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 Gene3D G3DSA:1.10.10.60 402 470 1.2E-11 T 29-03-2018 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 SUPERFAMILY SSF55785 3 120 1.74E-13 T 29-03-2018 IPR000014 PAS domain A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 Pfam PF08448 PAS fold 20 124 5.5E-9 T 29-03-2018 IPR013656 PAS fold-4 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 Gene3D G3DSA:3.30.450.20 10 158 7.5E-18 T 29-03-2018 A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 SMART SM00382 178 323 2.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12355 dd15d8c1c4e6ce818414fbfae6199590 473 SUPERFAMILY SSF52540 158 401 4.48E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 243 1.7E-48 T 29-03-2018 A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 7.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.2E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 Gene3D G3DSA:3.40.50.720 1 245 1.4E-64 T 29-03-2018 A616_RS19660 62c5e50c1e1d5695779eaa8209b9dbce 245 SUPERFAMILY SSF51735 8 244 8.41E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09465 486160a4883cb85d678740cfb906c418 233 PIRSF PIRSF000857 1 233 3.2E-96 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS09465 486160a4883cb85d678740cfb906c418 233 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 44 231 3.0E-76 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS09465 486160a4883cb85d678740cfb906c418 233 Gene3D G3DSA:3.40.50.620 1 233 8.0E-50 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS09465 486160a4883cb85d678740cfb906c418 233 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 38.419 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS09465 486160a4883cb85d678740cfb906c418 233 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 39 209 1.7E-50 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A616_RS09465 486160a4883cb85d678740cfb906c418 233 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 25 233 7.3E-79 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A616_RS09465 486160a4883cb85d678740cfb906c418 233 SUPERFAMILY SSF52402 15 195 2.48E-55 T 29-03-2018 A616_RS11945 018aa2e47d69b9eb9d330b95957e9e04 335 SUPERFAMILY SSF46689 277 309 7.77E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS11945 018aa2e47d69b9eb9d330b95957e9e04 335 Pfam PF13556 PucR C-terminal helix-turn-helix domain 275 330 4.8E-17 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS11945 018aa2e47d69b9eb9d330b95957e9e04 335 Gene3D G3DSA:1.10.10.60 263 310 1.8E-8 T 29-03-2018 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 8.5E-33 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 24.176 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 Gene3D G3DSA:2.60.15.10 1 89 2.4E-32 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 SUPERFAMILY SSF46604 88 131 5.75E-9 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 SUPERFAMILY SSF51344 3 85 1.57E-27 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 132 1.0E-15 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 83 5.0E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 Gene3D G3DSA:1.20.5.440 90 132 4.3E-15 T 29-03-2018 A616_RS29895 084d0e9804b891a59b224a95c34cf966 132 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 131 2.0E-40 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 SUPERFAMILY SSF51395 1 318 3.36E-71 T 29-03-2018 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 Gene3D G3DSA:3.20.20.70 1 330 8.9E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 317 2.3E-57 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 380 391 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 Gene3D G3DSA:3.30.70.20 331 381 1.5E-8 T 29-03-2018 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 SUPERFAMILY SSF54862 335 403 3.98E-11 T 29-03-2018 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 Gene3D G3DSA:3.30.70.20 382 415 1.9E-4 T 29-03-2018 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 Pfam PF14697 4Fe-4S dicluster domain 335 398 9.7E-23 T 29-03-2018 A616_RS18725 0ce8b090016a857d61ecf889283798d6 425 Pfam PF01180 Dihydroorotate dehydrogenase 28 302 1.4E-30 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 Pfam PF01895 PhoU domain 18 104 2.3E-24 T 29-03-2018 IPR026022 PhoU domain A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 Pfam PF01895 PhoU domain 123 205 8.5E-21 T 29-03-2018 IPR026022 PhoU domain A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 Gene3D G3DSA:1.20.58.220 111 218 8.3E-29 T 29-03-2018 A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 Gene3D G3DSA:1.20.58.220 1 110 7.7E-28 T 29-03-2018 A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 212 1.8E-68 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 SUPERFAMILY SSF109755 4 217 7.53E-70 T 29-03-2018 A616_RS08015 78c70560ca79be69e11e94ea886a0a84 218 PIRSF PIRSF003107 1 218 1.3E-72 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A616_RS29955 0ef9b4fe54e3d57ee5088bf452018d9b 272 SUPERFAMILY SSF53335 12 201 1.2E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS29955 0ef9b4fe54e3d57ee5088bf452018d9b 272 Pfam PF13489 Methyltransferase domain 24 199 4.3E-20 T 29-03-2018 A616_RS29955 0ef9b4fe54e3d57ee5088bf452018d9b 272 Gene3D G3DSA:3.40.50.150 1 268 1.1E-38 T 29-03-2018 A616_RS29955 0ef9b4fe54e3d57ee5088bf452018d9b 272 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 9 268 3.5E-59 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 A616_RS29955 0ef9b4fe54e3d57ee5088bf452018d9b 272 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 1 270 26.49 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 SUPERFAMILY SSF53850 18 265 1.61E-64 T 29-03-2018 A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 Gene3D G3DSA:3.40.190.10 43 188 3.6E-40 T 29-03-2018 A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 SMART SM00062 46 265 1.1E-67 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 Gene3D G3DSA:3.40.190.10 189 270 1.4E-14 T 29-03-2018 A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 263 1.7E-66 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS25020 f39468d5e2c1e7b1c12ba5c545b7e669 270 SMART SM00079 46 264 0.0035 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS05945 f0c80f4fd9b7f035c8e6a05d7e907717 265 Pfam PF06182 ABC-2 family transporter protein 40 264 4.5E-51 T 29-03-2018 IPR010390 Protein of unknown function DUF990 A616_RS26550 0890cbe1156d97b6506550d3bd0ee098 220 SUPERFAMILY SSF56784 6 217 7.19E-29 T 29-03-2018 IPR023214 HAD-like domain A616_RS26550 0890cbe1156d97b6506550d3bd0ee098 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 3.0E-18 T 29-03-2018 IPR023214 HAD-like domain A616_RS26550 0890cbe1156d97b6506550d3bd0ee098 220 Gene3D G3DSA:3.40.50.1000 2 220 9.6E-25 T 29-03-2018 IPR023214 HAD-like domain A616_RS29470 977f89831d934220fac23c46c489e6e9 349 SUPERFAMILY SSF53448 47 347 5.4E-65 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS29470 977f89831d934220fac23c46c489e6e9 349 Pfam PF00483 Nucleotidyl transferase 123 343 7.6E-38 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS29470 977f89831d934220fac23c46c489e6e9 349 Gene3D G3DSA:3.90.550.10 119 347 8.3E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS29470 977f89831d934220fac23c46c489e6e9 349 Gene3D G3DSA:3.10.580.10 1 118 7.2E-16 T 29-03-2018 A616_RS29470 977f89831d934220fac23c46c489e6e9 349 Pfam PF00571 CBS domain 9 53 4.1E-7 T 29-03-2018 IPR000644 CBS domain A616_RS29470 977f89831d934220fac23c46c489e6e9 349 Pfam PF00571 CBS domain 62 106 3.4E-4 T 29-03-2018 IPR000644 CBS domain A616_RS29470 977f89831d934220fac23c46c489e6e9 349 SUPERFAMILY SSF54631 7 55 2.33E-6 T 29-03-2018 A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 Gene3D G3DSA:1.20.5.50 496 690 6.3E-4 T 29-03-2018 A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 Pfam PF13476 AAA domain 5 274 3.3E-27 T 29-03-2018 A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 Gene3D G3DSA:3.40.50.300 882 1216 1.8E-22 T 29-03-2018 A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1109 1171 1.2E-12 T 29-03-2018 A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 Gene3D G3DSA:3.40.50.300 2 230 1.9E-24 T 29-03-2018 A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 SUPERFAMILY SSF52540 1106 1199 3.36E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27375 d7f8d6e62e68ef1f940aff66bc78edb9 1216 SUPERFAMILY SSF52540 18 192 3.36E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28955 149480e33c7ca6bed5075d94e5a2a30d 109 SMART SM00530 7 62 2.1E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS28955 149480e33c7ca6bed5075d94e5a2a30d 109 SUPERFAMILY SSF47413 2 66 1.75E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS28955 149480e33c7ca6bed5075d94e5a2a30d 109 Gene3D G3DSA:1.10.260.40 3 103 3.5E-19 T 29-03-2018 A616_RS28955 149480e33c7ca6bed5075d94e5a2a30d 109 Pfam PF01381 Helix-turn-helix 8 62 6.9E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 Pfam PF01514 Secretory protein of YscJ/FliF family 32 221 1.4E-50 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF A616_RS20040 69d7817e202832bbac0ab756f170566d 529 Gene3D G3DSA:3.30.70.1530 53 116 2.1E-4 T 29-03-2018 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 PIRSF PIRSF004862 1 529 3.2E-91 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 Pfam PF08345 Flagellar M-ring protein C-terminal 257 399 3.9E-17 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal A616_RS20040 69d7817e202832bbac0ab756f170566d 529 PRINTS PR01009 Flagellar M-ring protein signature 153 167 3.6E-14 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 PRINTS PR01009 Flagellar M-ring protein signature 349 373 3.6E-14 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 PRINTS PR01009 Flagellar M-ring protein signature 197 215 3.6E-14 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 PRINTS PR01009 Flagellar M-ring protein signature 121 139 3.6E-14 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 Gene3D G3DSA:1.20.5.100 441 471 1.2E-4 T 29-03-2018 A616_RS20040 69d7817e202832bbac0ab756f170566d 529 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 529 8.8E-91 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 1.4E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 Pfam PF00005 ABC transporter 26 184 4.4E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 Gene3D G3DSA:3.40.50.300 2 322 5.3E-81 T 29-03-2018 A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 SMART SM00382 34 234 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 1.9E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS11305 0321013d73fb45a57e2e1f1397ef8933 322 SUPERFAMILY SSF52540 5 254 9.82E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14180 88f8aafb2c0c01206bc8cc893b98777a 483 Pfam PF01425 Amidase 25 420 1.2E-81 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS14180 88f8aafb2c0c01206bc8cc893b98777a 483 SUPERFAMILY SSF75304 4 478 4.84E-112 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS14180 88f8aafb2c0c01206bc8cc893b98777a 483 Gene3D G3DSA:3.90.1300.10 2 483 3.6E-130 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS11030 96ebc646210df58dead24b56f5bbf1cb 164 Pfam PF07853 Protein of unknown function (DUF1648) 23 69 3.7E-18 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 4.9E-163 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 SUPERFAMILY SSF52402 230 396 1.05E-76 T 29-03-2018 A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 SUPERFAMILY SSF52402 454 576 1.05E-76 T 29-03-2018 A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 SUPERFAMILY SSF56235 1 226 2.92E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 2.5E-46 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 PIRSF PIRSF001589 1 612 2.9E-144 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 Pfam PF00733 Asparagine synthase 242 606 1.5E-98 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 Gene3D G3DSA:3.40.50.620 224 613 2.6E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS12280 bc14a8636ae4cc676108e08b1dc13650 615 Gene3D G3DSA:3.60.20.10 1 223 1.7E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 Gene3D G3DSA:1.10.1660.10 1 143 5.2E-30 T 29-03-2018 A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.5E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.5E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.5E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 SUPERFAMILY SSF46955 3 111 4.4E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 SMART SM00422 3 72 1.7E-26 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 Pfam PF07739 TipAS antibiotic-recognition domain 144 240 3.2E-8 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain A616_RS18065 d219d1ad1707dfff75679bd7e27d065d 245 Pfam PF13411 MerR HTH family regulatory protein 3 71 6.7E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 SMART SM00862 152 228 2.5E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 9.7E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 SUPERFAMILY SSF52172 2 133 1.85E-42 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 Gene3D G3DSA:1.10.10.10 121 230 1.7E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 Pfam PF00072 Response regulator receiver domain 6 115 4.6E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 SMART SM00448 4 114 3.2E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 Gene3D G3DSA:3.40.50.2300 1 120 2.0E-38 T 29-03-2018 A616_RS30975 8d7294b0111b8479495b1d49f43f49da 230 SUPERFAMILY SSF46894 127 228 3.97E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS17045 c9ce43a400c331c82271590786a9f1c0 401 Pfam PF00753 Metallo-beta-lactamase superfamily 95 282 3.3E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS17045 c9ce43a400c331c82271590786a9f1c0 401 SMART SM00894 364 400 2.4E-19 T 29-03-2018 IPR008613 Excalibur calcium-binding domain A616_RS17045 c9ce43a400c331c82271590786a9f1c0 401 SUPERFAMILY SSF56281 80 328 7.99E-51 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS17045 c9ce43a400c331c82271590786a9f1c0 401 Pfam PF05901 Excalibur calcium-binding domain 365 400 2.1E-14 T 29-03-2018 IPR008613 Excalibur calcium-binding domain A616_RS17045 c9ce43a400c331c82271590786a9f1c0 401 SMART SM00849 93 286 0.001 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS17045 c9ce43a400c331c82271590786a9f1c0 401 Gene3D G3DSA:3.60.15.10 37 309 2.7E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 SMART SM00490 539 620 9.1E-7 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 Pfam PF04851 Type III restriction enzyme, res subunit 317 446 2.3E-6 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 Gene3D G3DSA:3.40.50.300 496 660 6.5E-18 T 29-03-2018 A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 Gene3D G3DSA:3.40.50.300 278 460 3.4E-20 T 29-03-2018 A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 Pfam PF00271 Helicase conserved C-terminal domain 516 618 2.3E-11 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 SUPERFAMILY SSF52540 320 448 1.32E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 SUPERFAMILY SSF52540 489 632 1.32E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29600 f8533f69ffddbec96a483666ad5a95ed 662 SMART SM00487 291 470 2.4E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 411 1.6E-50 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 SUPERFAMILY SSF51735 3 167 1.29E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 Gene3D G3DSA:3.40.50.720 2 168 9.5E-30 T 29-03-2018 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 Pfam PF02056 Family 4 glycosyl hydrolase 5 186 3.0E-75 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 Gene3D G3DSA:3.90.110.10 170 440 2.0E-91 T 29-03-2018 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 4.0E-52 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 A616_RS30995 c2ec1427b09d648f5cf3a4769fed90e9 440 SUPERFAMILY SSF56327 172 437 3.22E-98 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A616_RS18005 702a46a86ee9302f25d4d91650270477 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 67 1.5E-23 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis A616_RS18005 702a46a86ee9302f25d4d91650270477 67 SUPERFAMILY SSF54285 3 66 5.37E-19 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A616_RS18005 702a46a86ee9302f25d4d91650270477 67 Gene3D G3DSA:3.10.20.30 1 67 2.3E-22 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS18005 702a46a86ee9302f25d4d91650270477 67 Pfam PF02597 ThiS family 3 67 5.8E-16 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 Gene3D G3DSA:3.40.710.10 349 683 2.0E-71 T 29-03-2018 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 SUPERFAMILY SSF54427 41 156 4.91E-23 T 29-03-2018 IPR032710 NTF2-like domain A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 38 159 4.2E-26 T 29-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 Pfam PF03717 Penicillin-binding Protein dimerisation domain 167 333 8.9E-36 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 Pfam PF00905 Penicillin binding protein transpeptidase domain 366 676 1.5E-65 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 SUPERFAMILY SSF56601 349 682 1.54E-84 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 Gene3D G3DSA:3.90.1310.10 154 348 6.3E-30 T 29-03-2018 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 Gene3D G3DSA:3.10.450.100 35 153 9.7E-29 T 29-03-2018 A616_RS25925 fe970e480572bac7c3071f45e6877da7 683 SUPERFAMILY SSF56519 161 348 4.05E-38 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS31885 3bf57ac5a2221e1c5463abed13bd9270 188 Gene3D G3DSA:3.40.50.360 1 178 1.2E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS31885 3bf57ac5a2221e1c5463abed13bd9270 188 Pfam PF03358 NADPH-dependent FMN reductase 1 142 7.0E-33 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A616_RS31885 3bf57ac5a2221e1c5463abed13bd9270 188 SUPERFAMILY SSF52218 1 167 6.68E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS05220 61d429eb1ae691706989d59c0513b365 177 Pfam PF08905 Domain of unknown function (DUF1850) 62 151 1.6E-22 T 29-03-2018 IPR015001 Protein of unknown function DUF1850 A616_RS16715 d2e05bebe7262d54ca216b5ff8cb1d3c 79 Gene3D G3DSA:1.10.3370.10 3 79 3.3E-4 T 29-03-2018 A616_RS16715 d2e05bebe7262d54ca216b5ff8cb1d3c 79 SUPERFAMILY SSF103491 7 76 4.97E-5 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS23675 0df83ce22ffbb11da6b5f91b66ee0d08 239 SMART SM00382 36 210 5.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23675 0df83ce22ffbb11da6b5f91b66ee0d08 239 Gene3D G3DSA:3.40.50.300 11 223 3.5E-21 T 29-03-2018 A616_RS23675 0df83ce22ffbb11da6b5f91b66ee0d08 239 Pfam PF13476 AAA domain 28 84 1.3E-8 T 29-03-2018 A616_RS23675 0df83ce22ffbb11da6b5f91b66ee0d08 239 SUPERFAMILY SSF52540 26 214 1.35E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23675 0df83ce22ffbb11da6b5f91b66ee0d08 239 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 151 196 1.7E-10 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 SUPERFAMILY SSF46894 156 226 5.1E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 SMART SM00421 164 221 6.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 217 1.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 Gene3D G3DSA:1.10.10.10 62 228 1.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 4.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 4.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS09445 c5779d8739dda2e6f80f37b0cb77b437 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 4.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 SMART SM01230 105 354 4.2E-140 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 SUPERFAMILY SSF54368 5 104 3.14E-33 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 2.1E-28 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 SUPERFAMILY SSF55931 105 441 8.93E-129 T 29-03-2018 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 Gene3D G3DSA:3.10.20.70 2 104 1.1E-36 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 7.5E-140 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 6.9E-177 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS19420 a87c84c86c1d8126513658a3f2f339fc 444 Gene3D G3DSA:3.30.590.10 105 444 1.8E-128 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A616_RS18590 6b083ca72c8b730735985bc071a7fa92 177 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A616_RS18590 6b083ca72c8b730735985bc071a7fa92 177 Pfam PF00578 AhpC/TSA family 37 154 5.3E-27 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS18590 6b083ca72c8b730735985bc071a7fa92 177 SUPERFAMILY SSF52833 34 174 1.15E-42 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS18590 6b083ca72c8b730735985bc071a7fa92 177 Gene3D G3DSA:3.40.30.10 18 170 5.1E-37 T 29-03-2018 A616_RS13995 75f37bea7dab1b8120127945d0cc18e5 159 SUPERFAMILY SSF54403 33 92 1.36E-12 T 29-03-2018 A616_RS13995 75f37bea7dab1b8120127945d0cc18e5 159 Gene3D G3DSA:3.10.450.40 95 156 8.3E-9 T 29-03-2018 A616_RS13995 75f37bea7dab1b8120127945d0cc18e5 159 Gene3D G3DSA:3.10.450.40 29 87 1.4E-13 T 29-03-2018 A616_RS13995 75f37bea7dab1b8120127945d0cc18e5 159 SUPERFAMILY SSF54403 96 154 5.44E-12 T 29-03-2018 A616_RS04565 9ffd3afe79f942715c3aea6dc3fb3430 380 Pfam PF07730 Histidine kinase 181 246 1.6E-20 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS04565 9ffd3afe79f942715c3aea6dc3fb3430 380 SUPERFAMILY SSF55874 250 368 2.88E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04565 9ffd3afe79f942715c3aea6dc3fb3430 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 285 365 8.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04565 9ffd3afe79f942715c3aea6dc3fb3430 380 Gene3D G3DSA:3.30.565.10 160 369 1.8E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04565 9ffd3afe79f942715c3aea6dc3fb3430 380 SMART SM00387 280 371 0.0082 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15695 8716df1567a507f67797f29218e66148 526 Pfam PF01483 Proprotein convertase P-domain 342 400 1.1E-4 T 29-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 A616_RS15695 8716df1567a507f67797f29218e66148 526 Gene3D G3DSA:3.40.50.1820 57 288 7.1E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15695 8716df1567a507f67797f29218e66148 526 SUPERFAMILY SSF53474 57 261 8.35E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15695 8716df1567a507f67797f29218e66148 526 Gene3D G3DSA:2.60.120.260 289 461 0.0016 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 SMART SM00342 97 180 5.4E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 PIRSF PIRSF000408 2 186 1.2E-85 T 29-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 164 180 8.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 149 164 8.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 Pfam PF12833 Helix-turn-helix domain 103 182 4.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 SUPERFAMILY SSF57884 7 89 1.57E-31 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 Gene3D G3DSA:1.10.10.60 131 186 6.0E-16 T 29-03-2018 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 Gene3D G3DSA:1.10.10.60 79 130 9.8E-16 T 29-03-2018 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 Pfam PF02805 Metal binding domain of Ada 9 72 3.7E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 SUPERFAMILY SSF46689 81 131 1.12E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 Gene3D G3DSA:3.40.10.10 2 75 7.7E-24 T 29-03-2018 IPR035451 Ada-like domain A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 134 176 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS01900 36dc9e848d4d60ef5bd608236fa99d61 186 SUPERFAMILY SSF46689 134 183 2.11E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 SUPERFAMILY SSF51905 3 329 1.17E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 Gene3D G3DSA:3.50.50.60 2 128 2.9E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 320 2.5E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.6E-5 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 183 9.6E-5 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 292 299 9.6E-5 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 9.6E-5 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 4.2E-8 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 4.2E-8 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.2E-8 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 4.2E-8 T 29-03-2018 A616_RS26270 896dd3a0ae654facbcc51df73949f64d 396 Gene3D G3DSA:3.50.50.60 129 330 1.2E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25835 7d180e8df64889d6458308dac64e691c 199 Gene3D G3DSA:3.40.50.880 6 198 1.0E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS25835 7d180e8df64889d6458308dac64e691c 199 SUPERFAMILY SSF52317 7 197 2.69E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS25835 7d180e8df64889d6458308dac64e691c 199 Pfam PF01965 DJ-1/PfpI family 7 178 3.5E-33 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS08255 27d56de1c9abd75874f4bdaf67448477 401 Gene3D G3DSA:1.20.1250.20 3 194 6.2E-35 T 29-03-2018 A616_RS08255 27d56de1c9abd75874f4bdaf67448477 401 SUPERFAMILY SSF103473 4 384 4.32E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08255 27d56de1c9abd75874f4bdaf67448477 401 Pfam PF07690 Major Facilitator Superfamily 15 260 6.9E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS08255 27d56de1c9abd75874f4bdaf67448477 401 Gene3D G3DSA:1.20.1250.20 197 395 9.0E-22 T 29-03-2018 A616_RS31555 16be32fdbf63997b2032af2c0b7e9b5b 528 Gene3D G3DSA:2.60.40.1630 117 268 9.4E-14 T 29-03-2018 A616_RS31555 16be32fdbf63997b2032af2c0b7e9b5b 528 Pfam PF13786 Domain of unknown function (DUF4179) 91 173 3.7E-14 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS31555 16be32fdbf63997b2032af2c0b7e9b5b 528 Gene3D G3DSA:2.60.40.1640 273 432 1.7E-8 T 29-03-2018 A616_RS31555 16be32fdbf63997b2032af2c0b7e9b5b 528 Pfam PF13490 Putative zinc-finger 13 36 3.8E-5 T 29-03-2018 IPR027383 Putative zinc-finger A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Gene3D G3DSA:3.40.1440.10 1 98 1.7E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 SUPERFAMILY SSF47781 502 589 5.72E-22 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Gene3D G3DSA:4.10.860.10 175 235 4.6E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Pfam PF01541 GIY-YIG catalytic domain 16 90 3.5E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Gene3D G3DSA:1.10.150.20 523 592 4.1E-15 T 29-03-2018 A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Pfam PF02151 UvrB/uvrC motif 197 230 1.1E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 SMART SM00465 15 95 2.4E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 570 1.2E-208 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 SUPERFAMILY SSF82771 14 97 2.09E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 SUPERFAMILY SSF46600 183 235 2.35E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.023 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 373 523 9.0E-56 T 29-03-2018 IPR001162 UvrC family homology region A616_RS09765 a14be2efb19ea3ca0bb0b43d5e0fdf78 593 Pfam PF14520 Helix-hairpin-helix domain 538 590 1.1E-6 T 29-03-2018 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 Pfam PF12072 Domain of unknown function (DUF3552) 6 198 6.2E-72 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 513 2.9E-247 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 TIGRFAM TIGR00277 HDIG: HDIG domain 325 402 6.8E-25 T 29-03-2018 IPR006675 HDIG domain A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 Pfam PF01966 HD domain 330 421 1.0E-17 T 29-03-2018 IPR006674 HD domain A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 SMART SM00471 325 431 6.3E-13 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 Hamap MF_00335 Ribonuclease Y [rny]. 5 513 26.124 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 Gene3D G3DSA:1.10.3210.10 237 468 9.9E-35 T 29-03-2018 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 SMART SM00322 201 268 1.1E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 SUPERFAMILY SSF54791 201 297 3.23E-17 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 Pfam PF00013 KH domain 206 263 6.4E-7 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 SUPERFAMILY SSF109604 309 460 3.37E-30 T 29-03-2018 A616_RS19610 cdaf95ab54e3e77438613de0e3074473 513 Gene3D G3DSA:3.30.300.20 25 236 4.0E-7 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS26845 4f8b6976989e52810b69c0239c9a5b52 242 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS26845 4f8b6976989e52810b69c0239c9a5b52 242 SUPERFAMILY SSF52540 2 236 4.61E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26845 4f8b6976989e52810b69c0239c9a5b52 242 Pfam PF00005 ABC transporter 18 166 1.9E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS26845 4f8b6976989e52810b69c0239c9a5b52 242 Gene3D G3DSA:3.40.50.300 1 241 1.6E-72 T 29-03-2018 A616_RS26845 4f8b6976989e52810b69c0239c9a5b52 242 PIRSF PIRSF039085 1 242 1.8E-117 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS26845 4f8b6976989e52810b69c0239c9a5b52 242 SMART SM00382 27 214 4.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 Pfam PF07687 Peptidase dimerisation domain 187 282 6.0E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 Gene3D G3DSA:3.40.630.10 252 394 5.6E-23 T 29-03-2018 A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 Gene3D G3DSA:3.40.630.10 1 251 9.6E-50 T 29-03-2018 A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 Pfam PF01546 Peptidase family M20/M25/M40 74 372 9.7E-35 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 SUPERFAMILY SSF55031 183 301 2.36E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 376 1.8E-118 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 SUPERFAMILY SSF53187 301 389 2.86E-87 T 29-03-2018 A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 SUPERFAMILY SSF53187 4 199 2.86E-87 T 29-03-2018 A616_RS09970 e22b9c830ffd651c08ea3cc219f066a2 394 PIRSF PIRSF005962 1 394 6.0E-127 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS13935 6efc95641b87026d5e1ad5a61892acd4 375 SUPERFAMILY SSF53756 6 371 1.26E-87 T 29-03-2018 A616_RS13935 6efc95641b87026d5e1ad5a61892acd4 375 Pfam PF00534 Glycosyl transferases group 1 186 347 3.2E-40 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS13935 6efc95641b87026d5e1ad5a61892acd4 375 Gene3D G3DSA:3.40.50.2000 185 352 1.7E-42 T 29-03-2018 A616_RS13935 6efc95641b87026d5e1ad5a61892acd4 375 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 1 370 1.6E-170 T 29-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 A616_RS13935 6efc95641b87026d5e1ad5a61892acd4 375 Pfam PF13439 Glycosyltransferase Family 4 12 176 9.1E-24 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS13935 6efc95641b87026d5e1ad5a61892acd4 375 Gene3D G3DSA:3.40.50.2000 1 184 3.0E-17 T 29-03-2018 A616_RS27275 e8769591d2f3c4f2922d45f1b350a07d 218 SMART SM00882 6 202 4.9E-78 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS27275 e8769591d2f3c4f2922d45f1b350a07d 218 Gene3D G3DSA:3.40.1080.10 3 214 1.3E-71 T 29-03-2018 A616_RS27275 e8769591d2f3c4f2922d45f1b350a07d 218 SUPERFAMILY SSF100950 4 215 3.11E-74 T 29-03-2018 A616_RS27275 e8769591d2f3c4f2922d45f1b350a07d 218 Pfam PF01144 Coenzyme A transferase 6 200 6.3E-42 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS27275 e8769591d2f3c4f2922d45f1b350a07d 218 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS27275 e8769591d2f3c4f2922d45f1b350a07d 218 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 207 5.9E-101 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 Pfam PF07836 DmpG-like communication domain 271 332 6.3E-32 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 SUPERFAMILY SSF89000 285 333 1.06E-17 T 29-03-2018 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 269 331 4.0E-22 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 340 177.187 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 Gene3D G3DSA:1.10.8.60 278 334 3.8E-30 T 29-03-2018 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 SUPERFAMILY SSF51569 1 269 3.85E-64 T 29-03-2018 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 Pfam PF00682 HMGL-like 5 259 8.9E-55 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 4 332 1.8E-158 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 A616_RS16240 5ee0f186ff270e1e06bb9a6738307560 340 Gene3D G3DSA:3.20.20.70 4 277 9.3E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 Gene3D G3DSA:1.10.10.10 1 87 2.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 Gene3D G3DSA:3.40.190.10 178 264 2.6E-17 T 29-03-2018 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 SUPERFAMILY SSF46785 1 111 2.99E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 Pfam PF03466 LysR substrate binding domain 90 287 1.5E-34 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 Gene3D G3DSA:3.40.190.10 88 177 3.1E-17 T 29-03-2018 A616_RS24740 84f3f2618e95051fd7e51b1b074d3923 297 SUPERFAMILY SSF53850 91 292 6.52E-34 T 29-03-2018 A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 6.1E-30 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 Pfam PF00005 ABC transporter 26 184 1.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 1.1E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 SMART SM00382 34 234 5.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 SUPERFAMILY SSF52540 5 254 3.31E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28610 c92e1c74c4cf1512c30197f07e0aeee2 348 Gene3D G3DSA:3.40.50.300 2 337 3.4E-79 T 29-03-2018 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 Gene3D G3DSA:3.40.190.10 87 179 6.7E-23 T 29-03-2018 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 Pfam PF03466 LysR substrate binding domain 86 290 2.6E-49 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 SUPERFAMILY SSF53850 88 292 1.16E-44 T 29-03-2018 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 Gene3D G3DSA:1.10.10.10 1 83 9.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 SUPERFAMILY SSF46785 2 110 4.88E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 Gene3D G3DSA:3.40.190.10 180 266 2.4E-24 T 29-03-2018 A616_RS21350 a7068145872b931cffcdf022f835ab7f 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.7E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS08730 be6084c1d9c99ab056b80c7ad2ba89fe 324 SUPERFAMILY SSF53807 48 319 2.0E-52 T 29-03-2018 A616_RS08730 be6084c1d9c99ab056b80c7ad2ba89fe 324 Gene3D G3DSA:3.40.50.1980 33 164 1.0E-24 T 29-03-2018 A616_RS08730 be6084c1d9c99ab056b80c7ad2ba89fe 324 Pfam PF01497 Periplasmic binding protein 99 301 1.3E-26 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS08730 be6084c1d9c99ab056b80c7ad2ba89fe 324 Gene3D G3DSA:3.40.50.1980 165 322 2.7E-28 T 29-03-2018 A616_RS07155 195009336da8ccae4375209dda920729 308 Gene3D G3DSA:1.10.4080.10 1 308 4.2E-95 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 A616_RS07155 195009336da8ccae4375209dda920729 308 Pfam PF03747 ADP-ribosylglycohydrolase 9 284 2.6E-74 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 A616_RS07155 195009336da8ccae4375209dda920729 308 SUPERFAMILY SSF101478 2 305 3.01E-80 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Gene3D G3DSA:3.40.1350.10 17 167 4.1E-19 T 29-03-2018 A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Gene3D G3DSA:3.30.420.10 495 708 6.3E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Pfam PF00665 Integrase core domain 509 628 2.6E-10 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Pfam PF08722 TnsA endonuclease N terminal 74 163 1.2E-6 T 29-03-2018 IPR014833 TnsA endonuclease, N-terminal A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Pfam PF09299 Mu transposase, C-terminal 723 772 8.6E-8 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 SUPERFAMILY SSF53098 507 690 3.19E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Gene3D G3DSA:1.10.10.60 424 484 8.4E-4 T 29-03-2018 A616_RS28765 459d1820385853fe1a68de7b96dbf0cb 909 Gene3D G3DSA:2.30.30.130 716 780 4.5E-8 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 Gene3D G3DSA:1.10.8.10 245 270 2.6E-7 T 29-03-2018 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 Gene3D G3DSA:1.10.8.10 271 295 0.003 T 29-03-2018 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 4 297 41.101 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 Gene3D G3DSA:3.40.50.10490 12 244 1.6E-54 T 29-03-2018 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 187 204 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 SUPERFAMILY SSF53697 8 250 1.54E-68 T 29-03-2018 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 Pfam PF13580 SIS domain 39 166 9.6E-15 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS26040 98acb62951b3b76e662fea94f53194e5 304 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 8 298 1.1E-120 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A616_RS18485 2e3e3b1d21900340a326be81b4c977bc 322 Gene3D G3DSA:3.40.50.1100 18 136 8.3E-22 T 29-03-2018 A616_RS18485 2e3e3b1d21900340a326be81b4c977bc 322 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 9 309 6.4E-129 T 29-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA A616_RS18485 2e3e3b1d21900340a326be81b4c977bc 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 2.9E-55 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS18485 2e3e3b1d21900340a326be81b4c977bc 322 SUPERFAMILY SSF53686 8 314 3.54E-73 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS18485 2e3e3b1d21900340a326be81b4c977bc 322 Gene3D G3DSA:3.40.50.1100 137 315 2.0E-42 T 29-03-2018 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 Gene3D G3DSA:3.40.718.10 213 354 8.8E-58 T 29-03-2018 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 Gene3D G3DSA:3.40.718.10 2 212 6.4E-63 T 29-03-2018 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 349 1.6E-94 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 SUPERFAMILY SSF53659 3 353 3.26E-119 T 29-03-2018 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 SMART SM01329 5 349 4.2E-176 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A616_RS30945 09b721139270b31e8df81deba0eabb8b 358 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 352 1.1E-164 T 29-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 A616_RS26095 d892c11ea228dfc1f4e27579d2c0ab1c 94 Pfam PF13799 Domain of unknown function (DUF4183) 23 91 1.3E-22 T 29-03-2018 IPR025237 Domain of unknown function DUF4183 A616_RS09725 4330f7d019ab500ae19eedde2d014792 116 Gene3D G3DSA:1.20.5.50 2 114 3.9E-9 T 29-03-2018 A616_RS01550 19b7e8d121f744be843ea32a4c7b4c46 290 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS01550 19b7e8d121f744be843ea32a4c7b4c46 290 Gene3D G3DSA:3.40.50.300 1 263 1.0E-63 T 29-03-2018 A616_RS01550 19b7e8d121f744be843ea32a4c7b4c46 290 Pfam PF00005 ABC transporter 23 173 3.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS01550 19b7e8d121f744be843ea32a4c7b4c46 290 SUPERFAMILY SSF52540 3 235 8.64E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01550 19b7e8d121f744be843ea32a4c7b4c46 290 SMART SM00382 32 222 1.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01550 19b7e8d121f744be843ea32a4c7b4c46 290 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 3.5E-113 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 A616_RS28185 368b28ae5a46d0447a80da279fe61d65 394 Pfam PF02595 Glycerate kinase family 3 377 2.7E-134 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS28185 368b28ae5a46d0447a80da279fe61d65 394 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 377 1.6E-135 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS28185 368b28ae5a46d0447a80da279fe61d65 394 SUPERFAMILY SSF110738 1 379 1.57E-122 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS28185 368b28ae5a46d0447a80da279fe61d65 394 PIRSF PIRSF006078 1 380 4.7E-114 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS28185 368b28ae5a46d0447a80da279fe61d65 394 Gene3D G3DSA:3.90.1510.10 42 280 6.6E-83 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 Gene3D G3DSA:3.40.190.10 175 261 1.1E-22 T 29-03-2018 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 Gene3D G3DSA:1.10.10.10 1 83 4.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 SUPERFAMILY SSF53850 89 286 8.22E-39 T 29-03-2018 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 Gene3D G3DSA:3.40.190.10 88 174 5.0E-22 T 29-03-2018 A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 SUPERFAMILY SSF46785 2 110 2.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10205 b31e33cde5ea708c540a93776674eb9b 289 Pfam PF03466 LysR substrate binding domain 87 282 5.3E-42 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS18075 2dae4dc80d91b801190657006e65ce2e 206 Pfam PF08241 Methyltransferase domain 2 88 2.3E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS18075 2dae4dc80d91b801190657006e65ce2e 206 SUPERFAMILY SSF53335 2 163 2.27E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS18075 2dae4dc80d91b801190657006e65ce2e 206 Gene3D G3DSA:3.40.50.150 1 190 4.8E-10 T 29-03-2018 A616_RS02355 dd2eb5c1d859fa6db0b118c87022f223 324 Gene3D G3DSA:2.40.50.140 132 226 3.1E-9 T 29-03-2018 A616_RS02355 dd2eb5c1d859fa6db0b118c87022f223 324 Gene3D G3DSA:2.40.50.140 239 323 5.8E-16 T 29-03-2018 A616_RS02355 dd2eb5c1d859fa6db0b118c87022f223 324 SUPERFAMILY SSF55383 54 135 1.31E-13 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02355 dd2eb5c1d859fa6db0b118c87022f223 324 Pfam PF07833 Copper amine oxidase N-terminal domain 52 140 2.1E-16 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02355 dd2eb5c1d859fa6db0b118c87022f223 324 Gene3D G3DSA:3.30.457.10 54 131 2.2E-16 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS26830 b7e09b65ce812c80c12df74c3a0b58f6 123 Pfam PF03960 ArsC family 43 117 3.2E-14 T 29-03-2018 IPR006660 Arsenate reductase-like A616_RS26830 b7e09b65ce812c80c12df74c3a0b58f6 123 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 6 119 5.0E-31 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR A616_RS26830 b7e09b65ce812c80c12df74c3a0b58f6 123 Gene3D G3DSA:3.40.30.10 1 119 6.7E-33 T 29-03-2018 A616_RS26830 b7e09b65ce812c80c12df74c3a0b58f6 123 SUPERFAMILY SSF52833 8 119 6.88E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 Gene3D G3DSA:2.40.40.20 653 773 5.4E-16 T 29-03-2018 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 Gene3D G3DSA:3.40.50.740 125 347 2.3E-36 T 29-03-2018 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 PIRSF PIRSF000144 87 761 1.4E-111 T 29-03-2018 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 Pfam PF01568 Molydopterin dinucleotide binding domain 655 751 1.6E-12 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 Gene3D G3DSA:3.40.50.740 348 623 6.7E-42 T 29-03-2018 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 Pfam PF00384 Molybdopterin oxidoreductase 123 575 4.3E-39 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 SUPERFAMILY SSF50692 644 761 4.07E-15 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 18 756 3.5E-272 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A616_RS06815 0bd97c8d29e8b77e6bede27047e8b82c 782 SUPERFAMILY SSF53706 71 644 4.45E-126 T 29-03-2018 A616_RS28625 167066276c7c03a6f5a86196d24b8ea1 581 Gene3D G3DSA:3.90.76.10 72 222 2.2E-32 T 29-03-2018 A616_RS28625 167066276c7c03a6f5a86196d24b8ea1 581 Gene3D G3DSA:3.10.105.10 320 542 3.4E-56 T 29-03-2018 A616_RS28625 167066276c7c03a6f5a86196d24b8ea1 581 PIRSF PIRSF002741 7 579 1.4E-108 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS28625 167066276c7c03a6f5a86196d24b8ea1 581 Gene3D G3DSA:3.40.190.10 223 319 9.9E-28 T 29-03-2018 A616_RS28625 167066276c7c03a6f5a86196d24b8ea1 581 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 479 1.1E-88 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS28625 167066276c7c03a6f5a86196d24b8ea1 581 SUPERFAMILY SSF53850 59 577 1.9E-121 T 29-03-2018 A616_RS22320 d07e30729aef909050322dea5fac67c9 265 SUPERFAMILY SSF52540 1 231 7.62E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22320 d07e30729aef909050322dea5fac67c9 265 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS22320 d07e30729aef909050322dea5fac67c9 265 Gene3D G3DSA:3.40.50.300 1 252 9.1E-56 T 29-03-2018 A616_RS22320 d07e30729aef909050322dea5fac67c9 265 Pfam PF00005 ABC transporter 22 177 4.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS22320 d07e30729aef909050322dea5fac67c9 265 SMART SM00382 31 226 6.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS16565 eb9304e910fa7a1f794786d4239337bf 119 SUPERFAMILY SSF52218 1 114 2.21E-18 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS16565 eb9304e910fa7a1f794786d4239337bf 119 TIGRFAM TIGR00333 nrdI: nrdI protein 3 111 1.7E-36 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A616_RS16565 eb9304e910fa7a1f794786d4239337bf 119 Gene3D G3DSA:3.40.50.360 1 119 9.5E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS16565 eb9304e910fa7a1f794786d4239337bf 119 Pfam PF07972 NrdI Flavodoxin like 3 110 1.3E-30 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A616_RS16565 eb9304e910fa7a1f794786d4239337bf 119 PIRSF PIRSF005087 1 119 1.6E-37 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A616_RS16565 eb9304e910fa7a1f794786d4239337bf 119 Hamap MF_00128 Protein NrdI [nrdI]. 1 119 25.028 T 29-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial A616_RS16245 22f001ff71043511833ce566fec428fc 264 Gene3D G3DSA:3.90.850.10 2 264 9.4E-44 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS16245 22f001ff71043511833ce566fec428fc 264 SUPERFAMILY SSF56529 6 259 2.09E-67 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS16245 22f001ff71043511833ce566fec428fc 264 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 102 259 1.3E-10 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS06515 87726d500b63b80a6e2936958a4db250 274 Gene3D G3DSA:2.40.50.140 173 272 0.021 T 29-03-2018 A616_RS06515 87726d500b63b80a6e2936958a4db250 274 SUPERFAMILY SSF56091 6 182 2.16E-38 T 29-03-2018 A616_RS06515 87726d500b63b80a6e2936958a4db250 274 SUPERFAMILY SSF50249 188 271 3.03E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS06515 87726d500b63b80a6e2936958a4db250 274 Gene3D G3DSA:3.30.1490.70 131 172 1.1E-7 T 29-03-2018 A616_RS06515 87726d500b63b80a6e2936958a4db250 274 Gene3D G3DSA:3.30.470.30 1 130 4.8E-32 T 29-03-2018 A616_RS06515 87726d500b63b80a6e2936958a4db250 274 Pfam PF01068 ATP dependent DNA ligase domain 12 182 1.6E-26 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 Gene3D G3DSA:3.40.1010.10 3 128 7.7E-33 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 240 2.2E-92 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 Gene3D G3DSA:3.30.950.10 129 257 9.8E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 Gene3D G3DSA:3.40.50.10090 258 364 1.8E-9 T 29-03-2018 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 SUPERFAMILY SSF69618 256 464 1.31E-15 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 PIRSF PIRSF036426 1 255 2.7E-100 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 PIRSF PIRSF036426 429 498 380.0 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 SUPERFAMILY SSF53790 2 255 4.06E-78 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 216 2.8E-45 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 Pfam PF02602 Uroporphyrinogen-III synthase HemD 269 466 1.9E-11 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A616_RS23490 eaf5d5463c5cbae7da77d81982dab71e 506 Gene3D G3DSA:3.40.50.10090 384 475 9.5E-6 T 29-03-2018 A616_RS21065 a5084f1c0d35f9a0de6917cf0497f86d 653 Gene3D G3DSA:2.70.98.10 21 243 2.4E-57 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A616_RS21065 a5084f1c0d35f9a0de6917cf0497f86d 653 SUPERFAMILY SSF48208 235 648 4.91E-102 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A616_RS21065 a5084f1c0d35f9a0de6917cf0497f86d 653 Gene3D G3DSA:1.50.10.10 244 594 4.6E-74 T 29-03-2018 A616_RS21065 a5084f1c0d35f9a0de6917cf0497f86d 653 Gene3D G3DSA:1.50.10.10 595 653 2.7E-12 T 29-03-2018 A616_RS21065 a5084f1c0d35f9a0de6917cf0497f86d 653 Pfam PF00723 Glycosyl hydrolases family 15 287 581 6.3E-17 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 SUPERFAMILY SSF52374 11 197 1.11E-132 T 29-03-2018 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 SUPERFAMILY SSF52374 383 635 1.11E-132 T 29-03-2018 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 Pfam PF08264 Anticodon-binding domain of tRNA 674 818 6.5E-32 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 SUPERFAMILY SSF47323 943 1021 2.35E-6 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 619 1.6E-188 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 Gene3D G3DSA:1.10.730.10 630 811 2.9E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 Gene3D G3DSA:3.40.50.620 377 624 1.9E-77 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 SUPERFAMILY SSF50677 199 383 2.09E-51 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 3.0E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 547 556 3.0E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 381 396 3.0E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 507 520 3.0E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 219 242 3.0E-29 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 6 828 6.8E-290 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1015 13.579 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 Gene3D G3DSA:3.90.740.10 165 376 2.6E-64 T 29-03-2018 A616_RS08990 123b36fcba6ed4f7682ba5defc9813ff 1026 SUPERFAMILY SSF47323 643 876 5.42E-53 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS06565 c468e7fddcf550aac0bb7cfc3299984d 220 Gene3D G3DSA:3.40.30.10 31 219 2.4E-36 T 29-03-2018 A616_RS06565 c468e7fddcf550aac0bb7cfc3299984d 220 Pfam PF00578 AhpC/TSA family 50 196 1.7E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS06565 c468e7fddcf550aac0bb7cfc3299984d 220 SUPERFAMILY SSF52833 48 219 1.38E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:1.10.1200.10 909 996 1.1E-7 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:1.10.1200.10 3633 3736 4.0E-10 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF53901 2248 2601 4.05E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF51735 1461 1663 6.4E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00826 1147 1314 7.5E-21 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00826 2861 3027 6.1E-6 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2614 2731 7.7E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 802 900 2.3E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2398 2414 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00825 Beta-ketoacyl synthase 2253 2672 9.1E-190 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00825 Beta-ketoacyl synthase 422 859 8.4E-188 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.50.150 1936 2090 6.2E-5 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF47336 2235 2263 1.03E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF47336 2120 2189 1.03E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 681 798 5.1E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2493 2610 4.0E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF53901 416 789 8.35E-87 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF14765 Polyketide synthase dehydratase 2861 3136 1.3E-32 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF14765 Polyketide synthase dehydratase 9 271 1.7E-16 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF14765 Polyketide synthase dehydratase 1147 1442 1.9E-66 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF51735 1674 1898 5.59E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.47.10 419 684 2.4E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:1.10.1200.10 306 418 6.1E-13 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:1.10.1200.10 2114 2237 4.1E-12 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.50.720 3174 3336 0.36 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.47.10 2244 2497 5.6E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF51735 3368 3585 7.06E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF53335 1952 2067 8.49E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF08659 KR domain 3369 3547 8.7E-42 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF08659 KR domain 1678 1856 9.1E-42 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3369 3549 6.3E-30 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1678 1858 7.4E-28 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF47336 921 997 1.19E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF51735 3155 3356 1.04E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM01294 310 376 5.5E-5 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF00550 Phosphopantetheine attachment site 312 376 9.5E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF00550 Phosphopantetheine attachment site 926 989 3.9E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF00550 Phosphopantetheine attachment site 2122 2183 1.8E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF00550 Phosphopantetheine attachment site 3656 3721 3.8E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 420 673 6.8E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2251 2485 4.1E-80 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF47336 309 433 1.44E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.50.720 3362 3619 2.8E-34 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.50.720 1670 1913 1.8E-34 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.10.129.10 2863 2989 1.7E-12 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.10.129.10 1151 1278 4.6E-23 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.10.129.10 4 113 3.9E-5 T 29-03-2018 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00823 Phosphopantetheine attachment site 2118 2188 2.3E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00823 Phosphopantetheine attachment site 309 380 7.2E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SMART SM00823 Phosphopantetheine attachment site 3654 3725 0.001 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.47.10 688 857 2.5E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 Gene3D G3DSA:3.40.47.10 2501 2670 1.3E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS22035 09d9afcadd5bbe5c1c461f2c1dcf82b1 3741 SUPERFAMILY SSF47336 3652 3725 3.14E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS29760 0b9b8c13da2b7b0a9b7d8b806a336eae 1501 Pfam PF00395 S-layer homology domain 1434 1485 3.5E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29760 0b9b8c13da2b7b0a9b7d8b806a336eae 1501 Pfam PF00395 S-layer homology domain 1291 1334 1.3E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29760 0b9b8c13da2b7b0a9b7d8b806a336eae 1501 Pfam PF00395 S-layer homology domain 1363 1408 2.4E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29590 10fc5f6df7dac0cdd6b8265e13fc4ec4 142 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 5 126 6.1E-43 T 29-03-2018 IPR022258 Flagellar operon protein YvyF A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 SUPERFAMILY SSF64484 5 1181 0.0 T 29-03-2018 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.681 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Pfam PF05000 RNA polymerase Rpb1, domain 4 693 761 2.1E-15 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 1.4E-89 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Pfam PF00623 RNA polymerase Rpb1, domain 2 379 474 2.6E-29 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 385 1.9E-9 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Gene3D G3DSA:2.40.40.20 335 477 3.0E-40 T 29-03-2018 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Pfam PF04998 RNA polymerase Rpb1, domain 5 771 1129 2.8E-67 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 664 4.6E-31 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 Gene3D G3DSA:2.40.50.100 912 1029 1.0E-39 T 29-03-2018 A616_RS01350 2a866127f2357627b2da40b6a7e81fc6 1208 SMART SM00663 224 503 3.3E-186 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 Gene3D G3DSA:3.20.80.10 127 271 2.6E-11 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 Gene3D G3DSA:1.10.1660.10 1 58 1.8E-19 T 29-03-2018 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.7E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 SMART SM00871 120 269 0.0012 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 Gene3D G3DSA:1.10.1660.10 59 126 9.9E-8 T 29-03-2018 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 SUPERFAMILY SSF55136 121 269 3.24E-5 T 29-03-2018 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 SMART SM00422 2 72 7.3E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17845 fffec592e1247e3f35d12890e4c568d8 271 SUPERFAMILY SSF46955 2 105 4.58E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS19595 d497d81c450117f1ab6820885e9baaea 312 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 308 1.3E-97 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A616_RS19595 d497d81c450117f1ab6820885e9baaea 312 Gene3D G3DSA:3.20.20.140 233 312 1.1E-22 T 29-03-2018 A616_RS19595 d497d81c450117f1ab6820885e9baaea 312 Gene3D G3DSA:3.20.20.140 1 232 9.8E-80 T 29-03-2018 A616_RS19595 d497d81c450117f1ab6820885e9baaea 312 SUPERFAMILY SSF51556 1 311 1.56E-88 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 SMART SM00228 305 395 0.0094 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 Gene3D G3DSA:2.40.10.10 190 280 2.3E-32 T 29-03-2018 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 Gene3D G3DSA:2.40.10.10 79 189 9.1E-29 T 29-03-2018 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 PRINTS PR00834 HtrA/DegQ protease family signature 153 173 7.1E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 PRINTS PR00834 HtrA/DegQ protease family signature 352 364 7.1E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 PRINTS PR00834 HtrA/DegQ protease family signature 194 218 7.1E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 PRINTS PR00834 HtrA/DegQ protease family signature 238 255 7.1E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 PRINTS PR00834 HtrA/DegQ protease family signature 260 277 7.1E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 PRINTS PR00834 HtrA/DegQ protease family signature 132 144 7.1E-38 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 Gene3D G3DSA:2.30.42.10 281 310 0.026 T 29-03-2018 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 Gene3D G3DSA:2.30.42.10 311 410 1.2E-19 T 29-03-2018 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 Pfam PF13365 Trypsin-like peptidase domain 120 267 8.1E-31 T 29-03-2018 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 Pfam PF13180 PDZ domain 306 404 1.6E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 SUPERFAMILY SSF50156 304 405 1.42E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS32095 0047e08e0b6d89b6a91c1e24e51a2aae 410 SUPERFAMILY SSF50494 85 300 5.11E-55 T 29-03-2018 IPR009003 Peptidase S1, PA clan A616_RS21315 32270139705c8c56d44340f21884b930 492 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 486 36.638 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A616_RS21315 32270139705c8c56d44340f21884b930 492 SUPERFAMILY SSF53244 332 488 8.5E-48 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS21315 32270139705c8c56d44340f21884b930 492 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 104 128 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A616_RS21315 32270139705c8c56d44340f21884b930 492 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 486 3.2E-173 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A616_RS21315 32270139705c8c56d44340f21884b930 492 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 4.3E-21 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS21315 32270139705c8c56d44340f21884b930 492 Pfam PF01225 Mur ligase family, catalytic domain 22 91 4.4E-12 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A616_RS21315 32270139705c8c56d44340f21884b930 492 Gene3D G3DSA:3.90.190.20 337 492 2.1E-49 T 29-03-2018 A616_RS21315 32270139705c8c56d44340f21884b930 492 SUPERFAMILY SSF63418 9 96 4.05E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A616_RS21315 32270139705c8c56d44340f21884b930 492 SUPERFAMILY SSF53623 97 331 1.14E-73 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS21315 32270139705c8c56d44340f21884b930 492 Gene3D G3DSA:3.40.1390.10 1 96 1.6E-26 T 29-03-2018 A616_RS21315 32270139705c8c56d44340f21884b930 492 Gene3D G3DSA:3.40.1190.10 97 336 3.3E-68 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS21315 32270139705c8c56d44340f21884b930 492 Pfam PF08245 Mur ligase middle domain 106 311 2.3E-58 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 13 418 3.5E-115 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 323 422 4.1E-19 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 Gene3D G3DSA:3.40.50.720 2 202 1.6E-41 T 29-03-2018 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 SUPERFAMILY SSF52413 308 435 3.01E-23 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 PIRSF PIRSF000124 12 437 1.5E-62 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 SMART SM00984 322 424 3.9E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 13 185 3.9E-40 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 PIRSF PIRSF500136 2 437 1.2E-146 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 SUPERFAMILY SSF48179 206 297 8.16E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 SUPERFAMILY SSF51735 13 197 1.22E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 Gene3D G3DSA:1.20.5.170 206 228 2.2E-11 T 29-03-2018 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 295 6.0E-23 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS31450 55acec818fd08a8570f010cb18b37c75 437 Gene3D G3DSA:3.40.50.720 229 436 5.4E-54 T 29-03-2018 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 Pfam PF00361 Proton-conducting membrane transporter 141 438 9.2E-68 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 502 2.8E-145 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 79 136 1.4E-7 T 29-03-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 256 280 5.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 396 422 5.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 344 363 5.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 177 201 5.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29840 c9375fc435e14d89ff77beaccfacfbcc 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 147 166 5.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 SUPERFAMILY SSF51735 2 256 5.96E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 194 0.0099 T 29-03-2018 A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 Pfam PF00106 short chain dehydrogenase 7 198 3.8E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 Gene3D G3DSA:3.40.50.720 1 281 2.9E-55 T 29-03-2018 A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS28485 074d3e23c5c0997710412051b48cf4f8 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS13365 65fbc0885bd3961e7366c992ebea79c3 552 Gene3D G3DSA:3.90.76.10 79 188 1.0E-31 T 29-03-2018 A616_RS13365 65fbc0885bd3961e7366c992ebea79c3 552 PIRSF PIRSF002741 2 552 3.9E-138 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS13365 65fbc0885bd3961e7366c992ebea79c3 552 Gene3D G3DSA:3.40.190.10 189 326 2.2E-44 T 29-03-2018 A616_RS13365 65fbc0885bd3961e7366c992ebea79c3 552 SUPERFAMILY SSF53850 49 548 1.81E-141 T 29-03-2018 A616_RS13365 65fbc0885bd3961e7366c992ebea79c3 552 Gene3D G3DSA:3.10.105.10 327 524 1.4E-57 T 29-03-2018 A616_RS13365 65fbc0885bd3961e7366c992ebea79c3 552 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 470 5.5E-94 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS12165 c891424c4f0c7e6c90978e2ebd50634f 652 PIRSF PIRSF006425 611 637 730.0 T 29-03-2018 IPR014441 Uncharacterised conserved protein UCP006425, beta-propeller-type A616_RS12165 c891424c4f0c7e6c90978e2ebd50634f 652 PIRSF PIRSF006425 344 568 4.2E-63 T 29-03-2018 IPR014441 Uncharacterised conserved protein UCP006425, beta-propeller-type A616_RS12165 c891424c4f0c7e6c90978e2ebd50634f 652 PIRSF PIRSF006425 1 179 1.1E-14 T 29-03-2018 IPR014441 Uncharacterised conserved protein UCP006425, beta-propeller-type A616_RS12165 c891424c4f0c7e6c90978e2ebd50634f 652 PIRSF PIRSF006425 190 331 0.034 T 29-03-2018 IPR014441 Uncharacterised conserved protein UCP006425, beta-propeller-type A616_RS12165 c891424c4f0c7e6c90978e2ebd50634f 652 Pfam PF09826 Beta propeller domain 95 641 2.3E-181 T 29-03-2018 IPR019198 Beta propeller domain-containing family A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 Gene3D G3DSA:3.40.190.10 90 178 2.2E-12 T 29-03-2018 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 SUPERFAMILY SSF53850 88 283 1.57E-29 T 29-03-2018 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.0E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 Gene3D G3DSA:1.10.10.10 1 83 9.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 Gene3D G3DSA:3.40.190.10 179 254 8.6E-9 T 29-03-2018 A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 SUPERFAMILY SSF46785 1 111 1.29E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07005 d640cf837f08a3d3b2db8abb3451ca4f 290 Pfam PF03466 LysR substrate binding domain 87 282 4.6E-31 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 SUPERFAMILY SSF55785 17 123 1.64E-10 T 29-03-2018 IPR000014 PAS domain A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Gene3D G3DSA:3.30.450.20 5 156 4.4E-11 T 29-03-2018 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 SUPERFAMILY SSF46689 363 470 3.58E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 SMART SM00091 18 86 0.002 T 29-03-2018 IPR000014 PAS domain A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Gene3D G3DSA:1.10.10.60 395 472 3.6E-19 T 29-03-2018 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Pfam PF02954 Bacterial regulatory protein, Fis family 429 468 1.9E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 SUPERFAMILY SSF52540 150 393 1.78E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 363 372 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 236 251 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Gene3D G3DSA:1.10.8.60 322 394 1.0E-22 T 29-03-2018 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Pfam PF08448 PAS fold 24 129 2.6E-7 T 29-03-2018 IPR013656 PAS fold-4 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 175 188 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Pfam PF00158 Sigma-54 interaction domain 151 316 5.2E-60 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 19 133 1.2E-5 T 29-03-2018 IPR000014 PAS domain A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 Gene3D G3DSA:3.40.50.300 157 321 3.7E-24 T 29-03-2018 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 SMART SM00382 171 313 4.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 434 451 6.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS12640 c296fb0b950380ce8e3ee3cc9b920dac 472 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 451 471 6.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 SMART SM00729 152 371 1.1E-51 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 Pfam PF00919 Uncharacterized protein family UPF0004 10 109 8.9E-30 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 Pfam PF04055 Radical SAM superfamily 157 329 3.7E-25 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 9 447 63.281 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 Gene3D G3DSA:2.40.50.140 386 448 7.2E-19 T 29-03-2018 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 10 445 3.2E-155 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 10 445 2.5E-132 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 156 176 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 SUPERFAMILY SSF102114 146 375 7.85E-58 T 29-03-2018 A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 Gene3D G3DSA:3.80.30.20 149 385 1.8E-46 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A616_RS19640 d14735694dd9e4a6bb887ed87ffacddc 448 Pfam PF01938 TRAM domain 383 448 5.8E-6 T 29-03-2018 IPR002792 TRAM domain A616_RS23260 d6060368511d1cde6b24ebfc227aca35 586 Pfam PF17482 Phage tail sheath C-terminal domain 474 580 7.0E-18 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain A616_RS23260 d6060368511d1cde6b24ebfc227aca35 586 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 318 472 4.8E-26 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 SMART SM00382 33 233 2.8E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 Pfam PF00005 ABC transporter 25 183 3.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 2.9E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 Gene3D G3DSA:3.40.50.300 1 334 2.8E-82 T 29-03-2018 A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 SUPERFAMILY SSF52540 4 254 2.66E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15860 6526795f347f87cb2b18075cbbaeee93 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 5.4E-22 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 Gene3D G3DSA:1.10.287.950 305 554 2.4E-52 T 29-03-2018 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 SUPERFAMILY SSF58104 284 552 5.36E-65 T 29-03-2018 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 SUPERFAMILY SSF58104 217 251 5.36E-65 T 29-03-2018 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 SMART SM00283 278 553 2.4E-65 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 503 2.0E-41 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 SMART SM00304 487 550 60.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 SMART SM00304 197 249 1.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 Gene3D G3DSA:1.10.287.950 207 304 2.1E-5 T 29-03-2018 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 Pfam PF00672 HAMP domain 199 241 3.1E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS10800 da783ed423979dd3eac7d49947f50dd8 554 Gene3D G3DSA:3.30.450.20 28 178 2.9E-17 T 29-03-2018 A616_RS10410 be33920d658a0e0ded656cba214af6c8 494 Gene3D G3DSA:3.10.350.10 451 494 5.6E-7 T 29-03-2018 A616_RS10410 be33920d658a0e0ded656cba214af6c8 494 Pfam PF01476 LysM domain 453 493 9.3E-8 T 29-03-2018 IPR018392 LysM domain A616_RS10410 be33920d658a0e0ded656cba214af6c8 494 SMART SM00257 450 493 8.5E-7 T 29-03-2018 IPR018392 LysM domain A616_RS10410 be33920d658a0e0ded656cba214af6c8 494 SUPERFAMILY SSF54106 450 493 1.31E-7 T 29-03-2018 IPR018392 LysM domain A616_RS28760 d3c64a75983a289c027a55a0729627eb 403 SUPERFAMILY SSF52540 149 316 8.76E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28760 d3c64a75983a289c027a55a0729627eb 403 SUPERFAMILY SSF52540 51 99 8.76E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28760 d3c64a75983a289c027a55a0729627eb 403 Gene3D G3DSA:3.40.50.300 3 240 6.2E-13 T 29-03-2018 A616_RS28760 d3c64a75983a289c027a55a0729627eb 403 Pfam PF05621 Bacterial TniB protein 64 308 8.9E-18 T 29-03-2018 IPR008868 Bacterial TniB A616_RS14575 b0c9a2dd418dc3cdb0b4b5aadba08b40 324 Gene3D G3DSA:3.20.20.30 1 317 1.7E-54 T 29-03-2018 A616_RS14575 b0c9a2dd418dc3cdb0b4b5aadba08b40 324 SUPERFAMILY SSF51679 23 311 8.77E-55 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS14575 b0c9a2dd418dc3cdb0b4b5aadba08b40 324 Pfam PF00296 Luciferase-like monooxygenase 26 234 3.5E-32 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS14575 b0c9a2dd418dc3cdb0b4b5aadba08b40 324 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 9 314 3.7E-114 T 29-03-2018 IPR020020 Luciferase-type oxidoreductase A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Gene3D G3DSA:1.10.1040.10 234 310 2.5E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 17 193 2.0E-41 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Gene3D G3DSA:1.20.5.170 213 233 8.1E-14 T 29-03-2018 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Gene3D G3DSA:3.40.50.720 320 430 2.5E-25 T 29-03-2018 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 SUPERFAMILY SSF48179 213 310 4.25E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 17 423 1.4E-129 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 SUPERFAMILY SSF51735 17 207 1.68E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS11910 a9544f855f38c96350c56c951f554b54 453 SMART SM00984 331 427 1.2E-27 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 214 304 8.3E-31 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 PIRSF PIRSF500136 6 441 4.8E-147 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 331 426 1.4E-20 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 SUPERFAMILY SSF52413 321 426 2.75E-24 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 PIRSF PIRSF000124 16 434 1.7E-62 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS11910 a9544f855f38c96350c56c951f554b54 453 Gene3D G3DSA:3.40.50.720 1 211 4.7E-35 T 29-03-2018 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 SMART SM00304 199 251 4.9E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 SUPERFAMILY SSF158472 201 249 1.57E-10 T 29-03-2018 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 462 1.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 SMART SM00388 252 318 1.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 1.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 1.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 1.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 1.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 SUPERFAMILY SSF55874 322 463 6.55E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 Gene3D G3DSA:1.10.287.130 242 314 6.3E-15 T 29-03-2018 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 317 2.2E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 Gene3D G3DSA:3.30.565.10 315 465 8.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 SUPERFAMILY SSF47384 235 317 4.32E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 Pfam PF00672 HAMP domain 200 247 7.0E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS03880 1809b678e7998d33b4ca834b49053d50 469 SMART SM00387 361 464 1.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 Pfam PF03129 Anticodon binding domain 475 566 1.9E-21 T 29-03-2018 IPR004154 Anticodon-binding A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 Pfam PF04073 Aminoacyl-tRNA editing domain 259 379 3.5E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 SUPERFAMILY SSF55681 407 478 3.56E-101 T 29-03-2018 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 SUPERFAMILY SSF55681 10 238 3.56E-101 T 29-03-2018 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 SUPERFAMILY SSF55826 219 389 4.19E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 SUPERFAMILY SSF52954 463 570 7.1E-32 T 29-03-2018 IPR004154 Anticodon-binding A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 459 1.6E-51 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 2 563 3.7E-228 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 Gene3D G3DSA:3.30.930.10 12 460 1.1E-97 T 29-03-2018 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 Gene3D G3DSA:3.40.50.800 461 576 2.1E-34 T 29-03-2018 IPR004154 Anticodon-binding A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 2 570 41.756 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 PIRSF PIRSF001535 2 572 5.9E-267 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 135 143 3.8E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 3.8E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 69 87 3.8E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS19830 933a45832ee233b1bf4aa4923cf3cccb 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 105 116 3.8E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 Gene3D G3DSA:3.30.420.40 27 169 5.5E-43 T 29-03-2018 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 Pfam PF00814 Glycoprotease family 49 332 1.9E-104 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 27 357 63.451 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 29 339 1.2E-134 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 SUPERFAMILY SSF53067 28 334 3.08E-44 T 29-03-2018 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 30 332 6.3E-108 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 123 142 3.7E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 179 200 3.7E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 168 3.7E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 289 298 3.7E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 102 122 3.7E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 30 43 3.7E-49 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02960 a0471def72e52295ffdb985ae5d87971 360 Gene3D G3DSA:3.30.420.40 170 315 4.0E-22 T 29-03-2018 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 Pfam PF00005 ABC transporter 385 534 2.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 Pfam PF00664 ABC transporter transmembrane region 53 323 2.9E-63 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 Gene3D G3DSA:1.20.1560.10 23 356 7.0E-90 T 29-03-2018 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 SMART SM00382 394 580 3.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 Gene3D G3DSA:3.40.50.300 359 610 1.7E-75 T 29-03-2018 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 SUPERFAMILY SSF90123 38 353 2.75E-90 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS08625 38a05606062cffe9cdb4f15ca2ced265 613 SUPERFAMILY SSF52540 358 604 4.86E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22765 d813d2200d4f99514d7449701f8f7f16 176 SUPERFAMILY SSF52972 7 172 2.83E-36 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A616_RS22765 d813d2200d4f99514d7449701f8f7f16 176 Gene3D G3DSA:3.90.950.10 6 175 1.8E-39 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A616_RS22765 d813d2200d4f99514d7449701f8f7f16 176 Pfam PF01931 Protein of unknown function DUF84 11 171 3.5E-40 T 29-03-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 A616_RS25335 2584a8a2177471fbeec1b6048e057130 162 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 34 158 1.3E-35 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 A616_RS25335 2584a8a2177471fbeec1b6048e057130 162 SUPERFAMILY SSF55620 29 158 6.12E-38 T 29-03-2018 A616_RS25335 2584a8a2177471fbeec1b6048e057130 162 Gene3D G3DSA:3.30.479.10 12 159 1.8E-41 T 29-03-2018 A616_RS25335 2584a8a2177471fbeec1b6048e057130 162 PIRSF PIRSF006113 29 158 1.9E-25 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 A616_RS25335 2584a8a2177471fbeec1b6048e057130 162 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 34 123 6.0E-30 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 A616_RS09320 7bcedd798d1f41889a62bfc7c5e0e96e 523 Gene3D G3DSA:3.10.105.10 299 492 2.3E-57 T 29-03-2018 A616_RS09320 7bcedd798d1f41889a62bfc7c5e0e96e 523 Gene3D G3DSA:3.90.76.10 63 165 2.9E-32 T 29-03-2018 A616_RS09320 7bcedd798d1f41889a62bfc7c5e0e96e 523 SUPERFAMILY SSF53850 42 522 2.02E-154 T 29-03-2018 A616_RS09320 7bcedd798d1f41889a62bfc7c5e0e96e 523 Gene3D G3DSA:3.40.190.10 166 298 1.9E-50 T 29-03-2018 A616_RS09320 7bcedd798d1f41889a62bfc7c5e0e96e 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 440 8.4E-108 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS09320 7bcedd798d1f41889a62bfc7c5e0e96e 523 PIRSF PIRSF002741 1 521 1.0E-132 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 Gene3D G3DSA:1.10.10.10 1 76 2.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.4E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 Gene3D G3DSA:3.90.1150.10 357 476 1.2E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 SUPERFAMILY SSF46785 5 84 1.37E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 Gene3D G3DSA:3.40.640.10 128 356 1.3E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 SMART SM00345 15 74 5.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 Pfam PF00155 Aminotransferase class I and II 117 456 1.0E-33 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 8.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 8.5E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS23870 dec18e0e22deb4c968b9d8e82cf18b8a 477 SUPERFAMILY SSF53383 103 474 2.3E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS04075 6cfbb2f0ba720e25af1cbcf2957599cf 296 SMART SM00046 3 131 2.3E-12 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A616_RS04075 6cfbb2f0ba720e25af1cbcf2957599cf 296 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 2.9E-36 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A616_RS04075 6cfbb2f0ba720e25af1cbcf2957599cf 296 SUPERFAMILY SSF111331 2 296 2.18E-81 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A616_RS04075 6cfbb2f0ba720e25af1cbcf2957599cf 296 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 2 296 9.0E-90 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase A616_RS04075 6cfbb2f0ba720e25af1cbcf2957599cf 296 Gene3D G3DSA:3.40.50.10330 1 132 9.6E-35 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A616_RS03255 e715fdc8922875c4d5fd26eb3355efe4 156 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A616_RS03255 e715fdc8922875c4d5fd26eb3355efe4 156 Gene3D G3DSA:3.40.140.10 1 156 3.7E-43 T 29-03-2018 A616_RS03255 e715fdc8922875c4d5fd26eb3355efe4 156 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 3.0E-23 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A616_RS03255 e715fdc8922875c4d5fd26eb3355efe4 156 SUPERFAMILY SSF53927 3 138 6.19E-45 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS07330 c5ed29164c27988b22d3b032482ec402 257 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 241 1.3E-60 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A616_RS07330 c5ed29164c27988b22d3b032482ec402 257 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 249 4.0E-78 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 A616_RS07330 c5ed29164c27988b22d3b032482ec402 257 Gene3D G3DSA:3.40.50.2300 64 248 5.6E-9 T 29-03-2018 A616_RS31010 da2a12c3e463a39a3e359fa1a2fffc37 447 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 436 9.6E-171 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A616_RS31010 da2a12c3e463a39a3e359fa1a2fffc37 447 Pfam PF02378 Phosphotransferase system, EIIC 29 361 4.8E-72 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A616_RS31010 da2a12c3e463a39a3e359fa1a2fffc37 447 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 436 9.6E-171 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 A616_RS31010 da2a12c3e463a39a3e359fa1a2fffc37 447 PIRSF PIRSF006351 1 444 7.1E-153 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 PRINTS PR00702 Acriflavin resistance protein family signature 434 457 1.5E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 PRINTS PR00702 Acriflavin resistance protein family signature 352 373 1.5E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.5E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 PRINTS PR00702 Acriflavin resistance protein family signature 380 404 1.5E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 1.5E-23 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82714 713 795 1.96E-8 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82693 40 128 1.36E-20 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82866 798 1013 2.09E-45 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Gene3D G3DSA:3.30.2090.10 177 265 3.4E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Gene3D G3DSA:1.20.1640.10 276 499 3.1E-36 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Gene3D G3DSA:1.20.1640.10 810 1027 3.9E-40 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82693 264 311 8.37E-13 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82693 142 178 8.37E-13 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Gene3D G3DSA:3.30.70.1430 38 139 1.5E-27 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82866 291 481 2.62E-35 T 29-03-2018 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Gene3D G3DSA:3.30.2090.10 713 797 9.7E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Pfam PF00873 AcrB/AcrD/AcrF family 1 1013 1.7E-187 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 SUPERFAMILY SSF82714 180 261 3.79E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS09040 e05cd29151492e63dd1ec26f51302743 1032 Gene3D G3DSA:3.30.70.1430 560 663 2.2E-8 T 29-03-2018 A616_RS30725 27316396791316b2e77879329be89cbf 486 Gene3D G3DSA:3.30.565.10 331 480 1.4E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30725 27316396791316b2e77879329be89cbf 486 SUPERFAMILY SSF55874 357 472 1.14E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30725 27316396791316b2e77879329be89cbf 486 Gene3D G3DSA:3.30.450.20 59 160 4.3E-5 T 29-03-2018 A616_RS30725 27316396791316b2e77879329be89cbf 486 Gene3D G3DSA:3.30.450.20 165 306 6.1E-6 T 29-03-2018 A616_RS30725 27316396791316b2e77879329be89cbf 486 SMART SM00387 375 474 5.5E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS30725 27316396791316b2e77879329be89cbf 486 Pfam PF07568 Histidine kinase 280 353 1.1E-24 T 29-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain A616_RS30725 27316396791316b2e77879329be89cbf 486 Pfam PF12282 Signal transduction histidine kinase 5 147 1.2E-33 T 29-03-2018 IPR022066 Signal transduction histidine kinase A616_RS30725 27316396791316b2e77879329be89cbf 486 Pfam PF13581 Histidine kinase-like ATPase domain 362 448 5.6E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 SMART SM01185 67 121 7.6E-23 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 4.6E-27 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 SMART SM00841 129 184 1.0E-32 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 SUPERFAMILY SSF50104 1 62 2.53E-21 T 29-03-2018 IPR008991 Translation protein SH3-like domain A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 8.1E-26 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Gene3D G3DSA:2.40.50.140 64 127 5.8E-24 T 29-03-2018 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Gene3D G3DSA:2.30.30.30 2 61 6.6E-26 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Gene3D G3DSA:2.40.50.140 129 184 2.9E-26 T 29-03-2018 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 PIRSF PIRSF005901 1 185 7.2E-70 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 7.6E-21 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 SUPERFAMILY SSF50249 65 129 1.84E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 SUPERFAMILY SSF50249 128 185 1.94E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 48.474 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A616_RS13005 afadf7c44b51b78c1924cd69396c9b5d 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 2.5E-78 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 SUPERFAMILY SSF52172 1 186 1.34E-32 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 Gene3D G3DSA:3.40.50.2300 1 139 1.0E-28 T 29-03-2018 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 Gene3D G3DSA:1.10.8.60 315 376 3.2E-17 T 29-03-2018 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 SMART SM00382 162 305 4.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 SUPERFAMILY SSF52540 144 381 9.47E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 Gene3D G3DSA:1.10.10.60 377 477 7.8E-7 T 29-03-2018 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 SMART SM00448 4 118 1.1E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 Pfam PF00072 Response regulator receiver domain 6 116 3.7E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 Pfam PF00158 Sigma-54 interaction domain 145 308 1.4E-64 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS25760 6bb19900593d63589ef8db7b99ed509f 478 Gene3D G3DSA:3.40.50.300 140 314 1.1E-24 T 29-03-2018 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 SUPERFAMILY SSF101801 257 328 6.41E-18 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 2.4E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 2.4E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 2.4E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 2.4E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 SUPERFAMILY SSF103039 46 229 6.45E-31 T 29-03-2018 IPR028976 CheC-like domain A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 Pfam PF02154 Flagellar motor switch protein FliM 39 229 2.1E-72 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 PIRSF PIRSF002888 1 331 5.2E-118 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 Gene3D G3DSA:3.40.1550.10 47 236 3.2E-51 T 29-03-2018 IPR028976 CheC-like domain A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 Gene3D G3DSA:2.30.330.10 237 331 2.0E-22 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 324 1.4E-113 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A616_RS19985 248e55c3518acc7b53c501fbfc35039a 331 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 323 4.7E-22 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 SMART SM00342 144 228 4.7E-32 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 SMART SM00448 1 114 6.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 197 212 5.1E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 212 228 5.1E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 Pfam PF12833 Helix-turn-helix domain 150 229 2.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 181 224 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 Gene3D G3DSA:1.10.10.60 133 177 3.3E-16 T 29-03-2018 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 Gene3D G3DSA:1.10.10.60 178 231 6.9E-15 T 29-03-2018 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 SUPERFAMILY SSF46689 181 230 1.66E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 Pfam PF00072 Response regulator receiver domain 3 114 5.6E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 Gene3D G3DSA:3.40.50.2300 1 132 5.7E-26 T 29-03-2018 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 SUPERFAMILY SSF46689 128 179 5.91E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS09160 0bd450ea36ff7f38349031b9cbdcd480 234 SUPERFAMILY SSF52172 1 125 8.82E-27 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS13115 2924cdc22e365e615e698d638f4e7296 137 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 5 130 5.9E-44 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 A616_RS13115 2924cdc22e365e615e698d638f4e7296 137 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 4 133 24.436 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 A616_RS13115 2924cdc22e365e615e698d638f4e7296 137 SUPERFAMILY SSF48013 6 127 7.33E-39 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A616_RS13115 2924cdc22e365e615e698d638f4e7296 137 Pfam PF01029 NusB family 7 129 1.0E-35 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A616_RS13115 2924cdc22e365e615e698d638f4e7296 137 Gene3D G3DSA:1.10.940.10 1 136 1.4E-44 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A616_RS09090 f29d2b39121f624381fc8334412b022f 365 SUPERFAMILY SSF50129 1 191 5.02E-64 T 29-03-2018 IPR011032 GroES-like A616_RS09090 f29d2b39121f624381fc8334412b022f 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 153 1.0E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS09090 f29d2b39121f624381fc8334412b022f 365 SMART SM00829 12 362 4.5E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS09090 f29d2b39121f624381fc8334412b022f 365 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A616_RS09090 f29d2b39121f624381fc8334412b022f 365 Pfam PF00107 Zinc-binding dehydrogenase 195 313 9.7E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS09090 f29d2b39121f624381fc8334412b022f 365 Gene3D G3DSA:3.40.50.10730 181 301 1.5E-31 T 29-03-2018 A616_RS09090 f29d2b39121f624381fc8334412b022f 365 SUPERFAMILY SSF51735 157 330 4.18E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09090 f29d2b39121f624381fc8334412b022f 365 Gene3D G3DSA:3.90.180.10 1 180 6.1E-47 T 29-03-2018 A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.783 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 Gene3D G3DSA:3.30.1390.20 4 58 4.7E-24 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 SUPERFAMILY SSF55129 1 59 7.19E-21 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 5.1E-25 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 PIRSF PIRSF002211 1 60 5.9E-28 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01490 df11470f7045a346d41f8618ba492ef4 61 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 3.9E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A616_RS20660 1be2e364e6e9fae4b812cf1f570909f1 169 SUPERFAMILY SSF55729 1 159 7.4E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS20660 1be2e364e6e9fae4b812cf1f570909f1 169 Gene3D G3DSA:3.40.630.30 1 164 7.2E-23 T 29-03-2018 A616_RS20660 1be2e364e6e9fae4b812cf1f570909f1 169 Pfam PF13420 Acetyltransferase (GNAT) domain 32 146 4.6E-7 T 29-03-2018 A616_RS22830 056998ce3ef1e1088db4618274a6b8ec 284 Gene3D G3DSA:1.10.3720.10 14 273 3.0E-51 T 29-03-2018 A616_RS22830 056998ce3ef1e1088db4618274a6b8ec 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 284 4.1E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS22830 056998ce3ef1e1088db4618274a6b8ec 284 SUPERFAMILY SSF161098 79 266 8.37E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS22830 056998ce3ef1e1088db4618274a6b8ec 284 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 9 54 4.3E-12 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS13865 555a13239204540fad58730916ff448a 315 Pfam PF13432 Tetratricopeptide repeat 181 237 1.3E-7 T 29-03-2018 A616_RS13865 555a13239204540fad58730916ff448a 315 Gene3D G3DSA:1.25.40.10 163 267 5.5E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 SUPERFAMILY SSF48452 178 299 5.46E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 SUPERFAMILY SSF48452 38 206 1.14E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 Pfam PF13181 Tetratricopeptide repeat 250 274 0.057 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 Gene3D G3DSA:1.25.40.10 133 162 5.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 Gene3D G3DSA:1.25.40.10 15 132 3.8E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 SMART SM00028 39 72 54.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 SMART SM00028 177 210 0.34 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 Gene3D G3DSA:1.25.40.10 268 303 0.076 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS13865 555a13239204540fad58730916ff448a 315 Pfam PF14559 Tetratricopeptide repeat 130 175 3.9E-6 T 29-03-2018 A616_RS13865 555a13239204540fad58730916ff448a 315 Pfam PF07721 Tetratricopeptide repeat 44 62 0.7 T 29-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 173 305 38.594 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 182 312 1.2E-64 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 Pfam PF01641 SelR domain 185 304 8.3E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 Gene3D G3DSA:2.170.150.20 174 321 2.2E-55 T 29-03-2018 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 Pfam PF01625 Peptide methionine sulfoxide reductase 11 161 9.0E-61 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 SUPERFAMILY SSF55068 6 172 1.09E-73 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 9 160 1.3E-63 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 SUPERFAMILY SSF51316 182 321 4.71E-61 T 29-03-2018 IPR011057 Mss4-like A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 Gene3D G3DSA:3.30.1060.10 2 173 3.4E-66 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A616_RS14815 b59b9adb951c7d5d0568e913308e854a 323 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 8 167 37.577 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 616 697 6.12E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 282 364 3.92E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 364 446 2.04E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 696 778 2.35E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 197 277 2.59E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 699 779 0.083 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 30 110 7.9E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 281 362 0.2 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 365 445 1.1E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 782 862 0.21 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 616 696 5.4E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 448 530 1.9E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 114 194 1.4E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 202 278 0.05 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SMART SM00635 533 613 1.7E-4 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 366 448 6.6E-15 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 198 280 4.5E-14 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 281 365 2.6E-16 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 449 532 1.4E-13 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 27 113 1.8E-13 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 114 197 1.5E-14 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 616 698 6.0E-16 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 533 615 8.9E-14 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 699 781 4.6E-14 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Gene3D G3DSA:2.60.40.1080 782 864 2.8E-11 T 29-03-2018 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Pfam PF02368 Bacterial Ig-like domain (group 2) 368 433 6.8E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Pfam PF02368 Bacterial Ig-like domain (group 2) 36 99 9.4E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Pfam PF02368 Bacterial Ig-like domain (group 2) 457 522 3.1E-7 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 Pfam PF02368 Bacterial Ig-like domain (group 2) 618 684 1.6E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 452 531 7.53E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS08120 aceeb7643a0931bbcf4faff2973b46c4 864 SUPERFAMILY SSF49373 32 111 4.08E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS15510 650468b9021f2021bddc242bb353419f 303 Gene3D G3DSA:3.40.190.10 90 203 2.4E-17 T 29-03-2018 A616_RS15510 650468b9021f2021bddc242bb353419f 303 Pfam PF03466 LysR substrate binding domain 89 297 1.1E-20 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS15510 650468b9021f2021bddc242bb353419f 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15510 650468b9021f2021bddc242bb353419f 303 SUPERFAMILY SSF53850 89 301 2.17E-23 T 29-03-2018 A616_RS15510 650468b9021f2021bddc242bb353419f 303 SUPERFAMILY SSF46785 1 111 7.65E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15510 650468b9021f2021bddc242bb353419f 303 Gene3D G3DSA:1.10.10.10 1 88 7.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 PRINTS PR00502 NUDIX hydrolase family signature 86 101 3.8E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 PRINTS PR00502 NUDIX hydrolase family signature 72 86 3.8E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 SUPERFAMILY SSF46785 234 299 9.79E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 SUPERFAMILY SSF55811 207 232 1.31E-30 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 SUPERFAMILY SSF55811 14 179 1.31E-30 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 Pfam PF00293 NUDIX domain 57 162 1.6E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 PIRSF PIRSF019423 35 187 4.8E-8 T 29-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 PIRSF PIRSF019423 166 302 2.5E-19 T 29-03-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 Gene3D G3DSA:3.90.79.10 26 230 1.1E-42 T 29-03-2018 A616_RS08935 4e780a72d06d2340ec5d153025bd5149 302 Gene3D G3DSA:1.10.10.10 231 302 2.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10215 0e7b14ee57a85196d0c09c1fab080a37 177 Gene3D G3DSA:3.40.30.10 43 174 2.2E-12 T 29-03-2018 A616_RS10215 0e7b14ee57a85196d0c09c1fab080a37 177 SUPERFAMILY SSF52833 41 158 6.43E-11 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS10215 0e7b14ee57a85196d0c09c1fab080a37 177 Pfam PF00578 AhpC/TSA family 50 157 2.2E-5 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS01600 b889fc8577733c40eb3cca9c395aace2 217 Pfam PF01944 Stage II sporulation protein M 19 199 3.5E-29 T 29-03-2018 IPR002798 Stage II sporulation protein M-like A616_RS02715 a7d4f51a509e031a78572c2e5a5e18df 254 Gene3D G3DSA:1.10.10.60 205 253 6.5E-10 T 29-03-2018 A616_RS02715 a7d4f51a509e031a78572c2e5a5e18df 254 Pfam PF12833 Helix-turn-helix domain 175 251 1.1E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS02715 a7d4f51a509e031a78572c2e5a5e18df 254 SMART SM00342 166 250 2.8E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS02715 a7d4f51a509e031a78572c2e5a5e18df 254 SUPERFAMILY SSF46689 202 252 6.27E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02715 a7d4f51a509e031a78572c2e5a5e18df 254 Gene3D G3DSA:1.10.10.60 148 204 3.0E-9 T 29-03-2018 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 Gene3D G3DSA:1.20.1250.20 204 395 9.8E-24 T 29-03-2018 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 SUPERFAMILY SSF103473 3 395 6.15E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 343 366 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 79 103 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 137 159 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 255 275 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 309 329 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 22 38 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 PRINTS PR01035 Tetracycline resistance protein signature 165 185 6.6E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 Pfam PF07690 Major Facilitator Superfamily 16 269 1.9E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS08985 afd554928bd9cbf01352b34c64e8a050 401 Gene3D G3DSA:1.20.1250.20 6 203 1.4E-45 T 29-03-2018 A616_RS15215 20643228b41bc6e408582472f9913728 322 SUPERFAMILY SSF51658 1 312 1.1E-52 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS15215 20643228b41bc6e408582472f9913728 322 Gene3D G3DSA:3.20.20.150 1 316 8.0E-51 T 29-03-2018 A616_RS15215 20643228b41bc6e408582472f9913728 322 Pfam PF01261 Xylose isomerase-like TIM barrel 20 243 2.6E-30 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS15215 20643228b41bc6e408582472f9913728 322 Pfam PF07582 AP endonuclease family 2 C terminus 269 322 2.5E-20 T 29-03-2018 IPR011418 AP endonuclease, family 2, C-terminal A616_RS10095 55ec66c70d03335abf7ee29cdecbbb43 479 SUPERFAMILY SSF53335 149 437 1.4E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10095 55ec66c70d03335abf7ee29cdecbbb43 479 Pfam PF05050 Methyltransferase FkbM domain 276 443 4.0E-18 T 29-03-2018 IPR006342 Methyltransferase FkbM A616_RS10095 55ec66c70d03335abf7ee29cdecbbb43 479 Gene3D G3DSA:3.40.50.150 256 459 4.7E-36 T 29-03-2018 A616_RS10095 55ec66c70d03335abf7ee29cdecbbb43 479 Gene3D G3DSA:3.40.50.150 40 166 0.011 T 29-03-2018 A616_RS10095 55ec66c70d03335abf7ee29cdecbbb43 479 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 273 414 4.8E-33 T 29-03-2018 IPR006342 Methyltransferase FkbM A616_RS27255 39afe7f21acdb70dfef5fdeaeed04980 167 PIRSF PIRSF019083 2 166 1.7E-38 T 29-03-2018 IPR016747 Phosphotransbutyrylase A616_RS27255 39afe7f21acdb70dfef5fdeaeed04980 167 Pfam PF04892 VanZ like family 11 153 4.2E-14 T 29-03-2018 IPR006976 VanZ-like A616_RS12000 31e0a3198cc8b08025be8724b65cb077 268 Pfam PF07730 Histidine kinase 80 132 1.1E-9 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS12000 31e0a3198cc8b08025be8724b65cb077 268 SMART SM00387 171 265 3.1E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS12000 31e0a3198cc8b08025be8724b65cb077 268 Gene3D G3DSA:3.30.565.10 65 260 3.6E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS12000 31e0a3198cc8b08025be8724b65cb077 268 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 173 259 6.4E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS12000 31e0a3198cc8b08025be8724b65cb077 268 SUPERFAMILY SSF55874 141 259 1.72E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 Gene3D G3DSA:3.40.350.10 1 127 2.8E-27 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 129 4.9E-24 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 SUPERFAMILY SSF55920 128 355 6.67E-79 T 29-03-2018 IPR000994 Peptidase M24 A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 Gene3D G3DSA:3.90.230.10 128 355 1.4E-77 T 29-03-2018 A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 285 297 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 Pfam PF00557 Metallopeptidase family M24 137 339 9.4E-66 T 29-03-2018 IPR000994 Peptidase M24 A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 PRINTS PR00599 Methionine aminopeptidase-1 signature 209 225 5.8E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 PRINTS PR00599 Methionine aminopeptidase-1 signature 307 319 5.8E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS25235 b96ef261481545deb15527ffc50bf5ca 355 SUPERFAMILY SSF53092 7 129 3.14E-25 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A616_RS05055 2dc9212c1c3baf704173a23129a5ee3b 118 Pfam PF13045 Protein of unknown function (DUF3905) 12 95 3.6E-47 T 29-03-2018 IPR024999 Protein of unknown function DUF3905 A616_RS20190 6e92a9d39daa7c061ed7ece928f19151 125 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 3 105 1.5E-23 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 A616_RS20190 6e92a9d39daa7c061ed7ece928f19151 125 Pfam PF02021 Uncharacterised protein family UPF0102 12 102 5.3E-26 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 A616_RS20190 6e92a9d39daa7c061ed7ece928f19151 125 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 115 21.311 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 A616_RS20190 6e92a9d39daa7c061ed7ece928f19151 125 Gene3D G3DSA:3.40.1350.10 11 125 2.7E-32 T 29-03-2018 A616_RS20190 6e92a9d39daa7c061ed7ece928f19151 125 SUPERFAMILY SSF52980 11 106 2.68E-21 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A616_RS10715 d4eb6e9ee630002935b34b64d901dc4c 412 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 124 387 5.1E-83 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A616_RS10715 d4eb6e9ee630002935b34b64d901dc4c 412 Gene3D G3DSA:1.20.1640.10 176 393 4.4E-26 T 29-03-2018 A616_RS10715 d4eb6e9ee630002935b34b64d901dc4c 412 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 156 380 5.2E-60 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A616_RS10715 d4eb6e9ee630002935b34b64d901dc4c 412 SUPERFAMILY SSF82866 197 392 3.14E-34 T 29-03-2018 A616_RS10715 d4eb6e9ee630002935b34b64d901dc4c 412 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 402 31.89 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A616_RS10715 d4eb6e9ee630002935b34b64d901dc4c 412 Pfam PF02355 Protein export membrane protein 219 387 7.0E-12 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A616_RS12810 88e4d6369788df9da1a0d40342c2d36a 127 SMART SM00450 32 127 3.2E-22 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12810 88e4d6369788df9da1a0d40342c2d36a 127 Pfam PF00581 Rhodanese-like domain 35 122 3.1E-17 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12810 88e4d6369788df9da1a0d40342c2d36a 127 SUPERFAMILY SSF52821 10 123 1.83E-29 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS12810 88e4d6369788df9da1a0d40342c2d36a 127 Gene3D G3DSA:3.40.250.10 25 127 7.0E-25 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 29-03-2018 IPR018253 DnaJ domain, conserved site A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 SUPERFAMILY SSF46565 1 83 1.7E-27 T 29-03-2018 IPR001623 DnaJ domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 SMART SM00271 2 60 1.6E-28 T 29-03-2018 IPR001623 DnaJ domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 PRINTS PR00625 DnaJ domain signature 40 60 6.6E-18 T 29-03-2018 IPR001623 DnaJ domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 PRINTS PR00625 DnaJ domain signature 23 38 6.6E-18 T 29-03-2018 IPR001623 DnaJ domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 PRINTS PR00625 DnaJ domain signature 5 23 6.6E-18 T 29-03-2018 IPR001623 DnaJ domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 Gene3D G3DSA:1.10.287.110 1 148 3.4E-28 T 29-03-2018 IPR001623 DnaJ domain A616_RS24590 a42772d8e1f8a0b093f387b916850f5d 148 Pfam PF00226 DnaJ domain 3 65 9.8E-25 T 29-03-2018 IPR001623 DnaJ domain A616_RS17975 f46c5d519d697d246196e4eeda6544a7 343 Pfam PF09084 NMT1/THI5 like 56 270 8.2E-66 T 29-03-2018 IPR015168 SsuA/THI5-like A616_RS17975 f46c5d519d697d246196e4eeda6544a7 343 Gene3D G3DSA:3.40.190.10 149 343 1.5E-23 T 29-03-2018 A616_RS17975 f46c5d519d697d246196e4eeda6544a7 343 SUPERFAMILY SSF53850 47 270 2.13E-38 T 29-03-2018 A616_RS17975 f46c5d519d697d246196e4eeda6544a7 343 Gene3D G3DSA:3.40.190.10 42 148 5.1E-22 T 29-03-2018 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 SUPERFAMILY SSF53901 8 275 1.8E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 4.0E-142 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 Pfam PF02803 Thiolase, C-terminal domain 278 397 1.4E-47 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 PIRSF PIRSF000429 2 399 4.0E-130 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 Pfam PF00108 Thiolase, N-terminal domain 8 269 6.8E-86 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 Gene3D G3DSA:3.40.47.10 5 277 1.1E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 Gene3D G3DSA:3.40.47.10 278 396 8.9E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 SUPERFAMILY SSF53901 278 398 8.65E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS27490 ce9555d65ff19af1c41436d8a147c8e5 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS13315 c817c9b57d9ed093afc0c68a3cbf4b97 185 SUPERFAMILY SSF55811 10 178 7.31E-53 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS13315 c817c9b57d9ed093afc0c68a3cbf4b97 185 Pfam PF00293 NUDIX domain 46 160 1.3E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS13315 c817c9b57d9ed093afc0c68a3cbf4b97 185 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS13315 c817c9b57d9ed093afc0c68a3cbf4b97 185 Gene3D G3DSA:3.90.79.10 8 184 1.6E-46 T 29-03-2018 A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 Gene3D G3DSA:3.40.50.880 620 842 3.7E-15 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 Gene3D G3DSA:2.60.40.10 514 608 0.0026 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 Gene3D G3DSA:2.60.40.10 387 513 1.0E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 SUPERFAMILY SSF102588 53 265 1.19E-31 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 SUPERFAMILY SSF52317 664 841 8.7E-12 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 403 467 1.4E-15 T 29-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 Gene3D G3DSA:3.40.50.10320 29 331 4.7E-28 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24960 80f0cee391190d80e341fc98bff41ae9 845 Pfam PF02585 GlcNAc-PI de-N-acetylase 56 193 8.5E-14 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A616_RS29665 5437d67767b1c5185c6ba98b6323a23c 408 Pfam PF00534 Glycosyl transferases group 1 215 351 5.0E-12 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS29665 5437d67767b1c5185c6ba98b6323a23c 408 Gene3D G3DSA:3.40.50.2000 216 369 7.6E-20 T 29-03-2018 A616_RS29665 5437d67767b1c5185c6ba98b6323a23c 408 Gene3D G3DSA:3.40.50.2000 18 215 5.1E-17 T 29-03-2018 A616_RS29665 5437d67767b1c5185c6ba98b6323a23c 408 SUPERFAMILY SSF53756 18 407 2.15E-40 T 29-03-2018 A616_RS29665 5437d67767b1c5185c6ba98b6323a23c 408 Pfam PF13579 Glycosyl transferase 4-like domain 92 199 2.9E-12 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS07495 095578826959ec769912754e45fe593b 79 Pfam PF14425 Immunity protein Imm3 17 74 1.5E-9 T 29-03-2018 IPR025678 Immunity protein Imm3 A616_RS27635 41300a473f5c3a7198cfa9bb061f7b0c 624 Pfam PF13519 von Willebrand factor type A domain 90 193 8.3E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27635 41300a473f5c3a7198cfa9bb061f7b0c 624 SUPERFAMILY SSF53300 90 193 6.67E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27635 41300a473f5c3a7198cfa9bb061f7b0c 624 Pfam PF07584 Aerotolerance regulator N-terminal 7 78 2.3E-18 T 29-03-2018 IPR024163 Aerotolerance regulator, N-terminal A616_RS27635 41300a473f5c3a7198cfa9bb061f7b0c 624 Gene3D G3DSA:3.40.50.880 208 498 0.001 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS27635 41300a473f5c3a7198cfa9bb061f7b0c 624 Gene3D G3DSA:3.40.50.410 85 207 4.6E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27915 d69cc78b8273fc19929ff6937b593377 308 Gene3D G3DSA:3.40.190.10 199 305 1.0E-14 T 29-03-2018 A616_RS27915 d69cc78b8273fc19929ff6937b593377 308 SUPERFAMILY SSF53850 44 198 3.8E-53 T 29-03-2018 A616_RS27915 d69cc78b8273fc19929ff6937b593377 308 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 205 308 4.9E-21 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A616_RS27915 d69cc78b8273fc19929ff6937b593377 308 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 46 187 7.5E-47 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A616_RS27915 d69cc78b8273fc19929ff6937b593377 308 Gene3D G3DSA:3.40.190.10 47 198 7.1E-43 T 29-03-2018 A616_RS27915 d69cc78b8273fc19929ff6937b593377 308 SUPERFAMILY SSF53850 200 308 5.52E-29 T 29-03-2018 A616_RS21625 11b446c9643cb185e1675d1f9e1cca3b 120 Pfam PF16258 Domain of unknown function (DUF4912) 19 120 1.3E-11 T 29-03-2018 IPR032585 Protein of unknown function DUF4912 A616_RS13385 a122861099a13fa04036c6f92deba825 319 Pfam PF00005 ABC transporter 28 178 4.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS13385 a122861099a13fa04036c6f92deba825 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 317 4.4E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS13385 a122861099a13fa04036c6f92deba825 319 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS13385 a122861099a13fa04036c6f92deba825 319 Gene3D G3DSA:3.40.50.300 4 319 5.9E-86 T 29-03-2018 A616_RS13385 a122861099a13fa04036c6f92deba825 319 SMART SM00382 36 228 4.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13385 a122861099a13fa04036c6f92deba825 319 SUPERFAMILY SSF52540 7 250 1.39E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13385 a122861099a13fa04036c6f92deba825 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 5.6E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS23395 a9adecae19c4d569609694181bc5a596 336 Pfam PF01522 Polysaccharide deacetylase 34 185 1.1E-6 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS23395 a9adecae19c4d569609694181bc5a596 336 Gene3D G3DSA:3.20.20.370 3 335 5.4E-28 T 29-03-2018 A616_RS23395 a9adecae19c4d569609694181bc5a596 336 SUPERFAMILY SSF88713 226 327 2.22E-15 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS23395 a9adecae19c4d569609694181bc5a596 336 SUPERFAMILY SSF88713 15 60 2.22E-15 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS23395 a9adecae19c4d569609694181bc5a596 336 SUPERFAMILY SSF88713 101 196 2.22E-15 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 Gene3D G3DSA:3.40.50.300 351 509 4.7E-37 T 29-03-2018 A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 SUPERFAMILY SSF52540 19 259 6.85E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 SUPERFAMILY SSF52540 355 519 1.37E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 SUPERFAMILY SSF52540 169 223 1.37E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 Gene3D G3DSA:3.40.50.10810 33 266 1.1E-39 T 29-03-2018 A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 SMART SM00490 391 471 5.2E-21 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 SMART SM00487 57 244 6.9E-31 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 Pfam PF00176 SNF2 family N-terminal domain 80 301 1.8E-34 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A616_RS12920 4944032dde7e851cdd65e7c75946359b 568 Pfam PF00271 Helicase conserved C-terminal domain 367 471 1.2E-20 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS06175 733aa386beae899bb30436e9c4f3b54e 139 Gene3D G3DSA:1.10.260.40 1 69 1.2E-10 T 29-03-2018 A616_RS06175 733aa386beae899bb30436e9c4f3b54e 139 SMART SM00530 7 67 3.6E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS06175 733aa386beae899bb30436e9c4f3b54e 139 Pfam PF01381 Helix-turn-helix 16 65 1.3E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS06175 733aa386beae899bb30436e9c4f3b54e 139 SUPERFAMILY SSF47413 3 70 1.1E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 Gene3D G3DSA:1.10.150.20 291 355 1.5E-9 T 29-03-2018 A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 SUPERFAMILY SSF143597 19 142 1.02E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 Pfam PF12826 Helix-hairpin-helix motif 307 346 2.1E-6 T 29-03-2018 A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 282 1.7E-53 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 6 355 44.409 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 137 4.7E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 SUPERFAMILY SSF47781 283 347 4.08E-12 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS01240 1c6388d9cf25be0c2e867d44cec77bb7 358 Gene3D G3DSA:3.40.1700.10 9 143 5.7E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A616_RS07995 a053cf44478b75d67b5b1074bc865613 427 Gene3D G3DSA:3.40.718.10 17 427 8.7E-136 T 29-03-2018 A616_RS07995 a053cf44478b75d67b5b1074bc865613 427 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 422 5.7E-118 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A616_RS07995 a053cf44478b75d67b5b1074bc865613 427 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 312 331 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A616_RS07995 a053cf44478b75d67b5b1074bc865613 427 SMART SM01329 28 423 1.3E-184 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A616_RS07995 a053cf44478b75d67b5b1074bc865613 427 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 4 427 4.7E-224 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A616_RS07995 a053cf44478b75d67b5b1074bc865613 427 SUPERFAMILY SSF53659 4 427 1.92E-142 T 29-03-2018 A616_RS08760 68a988630420e2d7438eba40059e1eac 282 Gene3D G3DSA:3.90.245.10 1 280 4.2E-46 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS08760 68a988630420e2d7438eba40059e1eac 282 SUPERFAMILY SSF53590 5 276 1.83E-41 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS08760 68a988630420e2d7438eba40059e1eac 282 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 12 267 1.9E-34 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS19490 47e8f635cb9590030ded51a4fd943478 79 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 30.485 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A616_RS19490 47e8f635cb9590030ded51a4fd943478 79 Pfam PF17209 Hfq protein 7 70 9.7E-34 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A616_RS19490 47e8f635cb9590030ded51a4fd943478 79 SUPERFAMILY SSF50182 6 65 1.9E-24 T 29-03-2018 IPR010920 LSM domain A616_RS19490 47e8f635cb9590030ded51a4fd943478 79 Gene3D G3DSA:2.30.30.100 4 74 3.6E-34 T 29-03-2018 A616_RS19490 47e8f635cb9590030ded51a4fd943478 79 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 1.3E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 Gene3D G3DSA:2.40.50.140 170 237 6.9E-9 T 29-03-2018 A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 PIRSF PIRSF012524 19 301 1.1E-89 T 29-03-2018 IPR014464 Conserved virulence factor B A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 Pfam PF13509 S1 domain 23 80 1.1E-21 T 29-03-2018 A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 Gene3D G3DSA:1.10.10.10 240 299 4.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 Gene3D G3DSA:2.40.50.140 82 161 0.0064 T 29-03-2018 A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 Gene3D G3DSA:2.40.50.140 23 77 5.6E-4 T 29-03-2018 A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 SMART SM00316 168 230 4.1E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS05210 8d72cb965ad9aa7f877f6b691c392cd2 306 SMART SM00316 21 81 0.018 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 Pfam PF04324 BFD-like [2Fe-2S] binding domain 389 443 1.1E-10 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 Pfam PF01266 FAD dependent oxidoreductase 7 357 1.7E-60 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 Gene3D G3DSA:3.50.50.60 1 67 0.0027 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 SUPERFAMILY SSF54373 226 316 3.53E-7 T 29-03-2018 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 SUPERFAMILY SSF51905 319 361 1.34E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 SUPERFAMILY SSF51905 5 224 1.34E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 Gene3D G3DSA:3.30.9.10 89 167 3.4E-7 T 29-03-2018 A616_RS23735 ccb959f43be21d7da5ae172f85bd4074 471 Gene3D G3DSA:3.30.9.10 168 318 5.4E-27 T 29-03-2018 A616_RS26160 5423981222e702e25a12af5970aff4e3 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 175 7.7E-18 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26160 5423981222e702e25a12af5970aff4e3 191 Gene3D G3DSA:1.10.10.10 105 191 6.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26160 5423981222e702e25a12af5970aff4e3 191 SUPERFAMILY SSF88659 120 177 1.38E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26160 5423981222e702e25a12af5970aff4e3 191 Pfam PF04545 Sigma-70, region 4 127 175 4.0E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26160 5423981222e702e25a12af5970aff4e3 191 Pfam PF04542 Sigma-70 region 2 26 91 1.8E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26160 5423981222e702e25a12af5970aff4e3 191 Gene3D G3DSA:1.10.1740.10 1 104 9.1E-16 T 29-03-2018 A616_RS26160 5423981222e702e25a12af5970aff4e3 191 SUPERFAMILY SSF88946 1 99 4.51E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08205 afd59c824a0dac510dbc75060fa1c561 176 Pfam PF07155 ECF-type riboflavin transporter, S component 12 171 3.2E-38 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A616_RS15605 a21108e8df183c0f8c1a3cf9bfef4585 212 Pfam PF09414 RNA ligase 33 186 1.7E-25 T 29-03-2018 IPR021122 RNA ligase domain, REL/Rln2 A616_RS15605 a21108e8df183c0f8c1a3cf9bfef4585 212 SUPERFAMILY SSF56091 3 209 6.37E-39 T 29-03-2018 A616_RS21540 8f2069e14c2c2e043f67c3d2b07e768e 133 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 29.482 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS21540 8f2069e14c2c2e043f67c3d2b07e768e 133 SUPERFAMILY SSF56276 5 116 1.73E-39 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A616_RS21540 8f2069e14c2c2e043f67c3d2b07e768e 133 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 3.7E-42 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS21540 8f2069e14c2c2e043f67c3d2b07e768e 133 Gene3D G3DSA:3.60.90.10 1 124 1.9E-42 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A616_RS21540 8f2069e14c2c2e043f67c3d2b07e768e 133 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 3.2E-36 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 SUPERFAMILY SSF52172 2 127 1.71E-41 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 Gene3D G3DSA:1.10.10.10 130 238 1.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 SMART SM00862 161 232 5.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 SMART SM00448 4 114 6.5E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 Gene3D G3DSA:3.40.50.2300 1 129 1.1E-37 T 29-03-2018 A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 Pfam PF00072 Response regulator receiver domain 6 115 2.3E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 SUPERFAMILY SSF46894 140 233 1.08E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS00175 61ae7d1b5e27000f1f16594358dccaac 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 232 2.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS27340 9653107cd8c409f28324e7b095e751a8 515 Gene3D G3DSA:1.20.1250.20 12 206 3.9E-31 T 29-03-2018 A616_RS27340 9653107cd8c409f28324e7b095e751a8 515 SUPERFAMILY SSF103473 476 505 4.97E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS27340 9653107cd8c409f28324e7b095e751a8 515 SUPERFAMILY SSF103473 253 423 4.97E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS27340 9653107cd8c409f28324e7b095e751a8 515 SUPERFAMILY SSF103473 15 203 4.97E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS27340 9653107cd8c409f28324e7b095e751a8 515 Gene3D G3DSA:1.20.1250.20 263 510 1.2E-15 T 29-03-2018 A616_RS27340 9653107cd8c409f28324e7b095e751a8 515 Pfam PF07690 Major Facilitator Superfamily 28 413 4.9E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS10320 728f7de10ff954f5b90bd82b74d6bd9f 450 SUPERFAMILY SSF140657 323 438 3.53E-11 T 29-03-2018 A616_RS10320 728f7de10ff954f5b90bd82b74d6bd9f 450 Pfam PF07555 beta-N-acetylglucosaminidase 10 311 2.0E-94 T 29-03-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 A616_RS10320 728f7de10ff954f5b90bd82b74d6bd9f 450 SUPERFAMILY SSF51445 8 314 4.98E-86 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS10320 728f7de10ff954f5b90bd82b74d6bd9f 450 Gene3D G3DSA:3.20.20.80 7 310 1.7E-94 T 29-03-2018 A616_RS10320 728f7de10ff954f5b90bd82b74d6bd9f 450 Gene3D G3DSA:1.20.58.460 311 450 2.7E-26 T 29-03-2018 A616_RS29405 15a75454633d8616b3d1378205b61dac 187 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 97 3.8E-31 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A616_RS29405 15a75454633d8616b3d1378205b61dac 187 Gene3D G3DSA:3.30.160.100 1 98 3.6E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A616_RS29405 15a75454633d8616b3d1378205b61dac 187 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 187 25.259 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid A616_RS29405 15a75454633d8616b3d1378205b61dac 187 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 94 2.2E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A616_RS29405 15a75454633d8616b3d1378205b61dac 187 SUPERFAMILY SSF69754 2 101 6.28E-33 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A616_RS29405 15a75454633d8616b3d1378205b61dac 187 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 131 183 1.1E-28 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal A616_RS06825 00e315a87179bb6d22b226664da30c85 171 Gene3D G3DSA:3.40.50.300 2 167 8.2E-28 T 29-03-2018 A616_RS06825 00e315a87179bb6d22b226664da30c85 171 SUPERFAMILY SSF52540 5 163 4.63E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06825 00e315a87179bb6d22b226664da30c85 171 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 7 135 4.1E-39 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A616_RS06825 00e315a87179bb6d22b226664da30c85 171 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 7 161 5.0E-41 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A616_RS03000 0d21369ff2fffafff101c26d00148723 121 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 8.6E-19 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A616_RS03000 0d21369ff2fffafff101c26d00148723 121 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 78 19.824 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A616_RS03000 0d21369ff2fffafff101c26d00148723 121 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 4.5E-6 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A616_RS03000 0d21369ff2fffafff101c26d00148723 121 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 4.5E-6 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A616_RS03000 0d21369ff2fffafff101c26d00148723 121 Pfam PF02416 mttA/Hcf106 family 4 55 6.9E-21 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Pfam PF00122 E1-E2 ATPase 236 416 6.1E-55 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Gene3D G3DSA:3.40.1110.10 459 559 7.5E-28 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 186 489 7.9E-98 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 172 738 7.3E-125 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF55008 46 112 6.54E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF81665 685 724 7.06E-18 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF81665 336 430 7.06E-18 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF81665 185 236 7.06E-18 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 185 738 1.1E-188 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 592 1.7E-24 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 654 1.7E-24 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 436 450 1.7E-24 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 285 299 1.7E-24 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 671 1.7E-24 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 570 1.7E-24 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Gene3D G3DSA:1.20.1110.10 115 458 2.3E-43 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00941 Cadmium-transporting ATPase signature 301 317 9.7E-25 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00941 Cadmium-transporting ATPase signature 149 166 9.7E-25 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00941 Cadmium-transporting ATPase signature 320 334 9.7E-25 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00941 Cadmium-transporting ATPase signature 50 59 9.7E-25 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00941 Cadmium-transporting ATPase signature 220 240 9.7E-25 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 PRINTS PR00941 Cadmium-transporting ATPase signature 61 82 9.7E-25 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Pfam PF00403 Heavy-metal-associated domain 49 107 1.0E-8 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF81653 238 335 2.62E-25 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Pfam PF00702 haloacid dehalogenase-like hydrolase 432 649 2.3E-44 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 208 718 7.1E-97 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Gene3D G3DSA:3.30.70.100 43 114 3.4E-15 T 29-03-2018 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF56784 531 736 1.02E-55 T 29-03-2018 IPR023214 HAD-like domain A616_RS01995 1045e72895bec4fbfba17c095e783477 743 SUPERFAMILY SSF56784 435 454 1.02E-55 T 29-03-2018 IPR023214 HAD-like domain A616_RS01995 1045e72895bec4fbfba17c095e783477 743 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 438 444 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A616_RS01995 1045e72895bec4fbfba17c095e783477 743 Gene3D G3DSA:3.40.50.1000 560 695 4.6E-38 T 29-03-2018 IPR023214 HAD-like domain A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 Gene3D G3DSA:1.10.8.60 350 425 5.1E-21 T 29-03-2018 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 SUPERFAMILY SSF52540 160 409 6.15E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 337 4.7E-46 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 ProSitePatterns PS00674 AAA-protein family signature. 308 326 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 Gene3D G3DSA:3.40.50.300 474 652 0.25 T 29-03-2018 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 SMART SM00382 201 340 2.1E-25 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 117 607 1.0E-240 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 SUPERFAMILY SSF140990 419 611 2.62E-72 T 29-03-2018 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 Pfam PF01434 Peptidase family M41 398 606 1.1E-83 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 619 38.177 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A616_RS00800 d940c7af259b29b1971b93285ba78c98 652 Gene3D G3DSA:3.40.50.300 144 349 3.3E-64 T 29-03-2018 A616_RS11735 63186efaf7723019c768cf0bd7e4442c 226 SUPERFAMILY SSF56219 1 218 5.89E-39 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS11735 63186efaf7723019c768cf0bd7e4442c 226 Gene3D G3DSA:3.60.10.10 1 217 6.7E-36 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS11735 63186efaf7723019c768cf0bd7e4442c 226 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 209 9.7E-16 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 Pfam PF00158 Sigma-54 interaction domain 172 339 1.0E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 Gene3D G3DSA:1.10.8.60 346 412 2.3E-21 T 29-03-2018 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 386 395 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 SMART SM00382 192 336 1.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 Pfam PF02954 Bacterial regulatory protein, Fis family 453 479 4.4E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 SUPERFAMILY SSF46689 429 482 1.46E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 SUPERFAMILY SSF52540 172 417 2.32E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 Gene3D G3DSA:3.40.50.300 168 345 2.8E-24 T 29-03-2018 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 196 209 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 Gene3D G3DSA:1.10.10.60 413 482 5.0E-11 T 29-03-2018 A616_RS30385 b42bacfdd735b4319917dab5f0938fa2 484 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 259 274 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Gene3D G3DSA:3.20.20.60 165 319 7.0E-65 T 29-03-2018 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Pfam PF00391 PEP-utilising enzyme, mobile domain 502 574 4.8E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Gene3D G3DSA:3.50.30.10 473 584 1.1E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Gene3D G3DSA:3.20.20.60 1 83 3.9E-22 T 29-03-2018 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 471 1.8E-189 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 SUPERFAMILY SSF52009 464 581 2.09E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 SUPERFAMILY SSF50800 71 166 9.77E-28 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 SUPERFAMILY SSF51621 166 342 3.14E-105 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 SUPERFAMILY SSF51621 2 76 3.14E-105 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Pfam PF00224 Pyruvate kinase, barrel domain 3 342 2.9E-155 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 SUPERFAMILY SSF52935 321 472 7.06E-44 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Gene3D G3DSA:2.40.33.10 84 164 1.0E-31 T 29-03-2018 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Gene3D G3DSA:3.40.1380.20 320 472 2.0E-54 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 469 3.6E-37 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 292 310 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 311 327 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 267 291 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS07955 acbc6d7b668c2bb612c3180ad2870133 584 PRINTS PR01050 Pyruvate kinase family signature 215 241 1.4E-81 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 SMART SM00345 17 76 5.0E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 SUPERFAMILY SSF46785 13 80 7.86E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 Pfam PF07840 FadR C-terminal domain 77 230 5.4E-35 T 29-03-2018 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 Gene3D G3DSA:1.10.10.10 7 84 2.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 Gene3D G3DSA:1.20.120.530 85 237 1.0E-16 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 3.6E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 SMART SM00419 32 78 0.0062 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS09295 b19de95649cd97ac6c84a5fef6230f8b 238 SUPERFAMILY SSF48008 91 230 5.49E-30 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 Gene3D G3DSA:3.90.1170.20 1 136 2.8E-44 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 111 276 2.6E-63 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 Gene3D G3DSA:3.20.20.70 137 267 3.5E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 12 276 8.9E-105 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 PIRSF PIRSF006250 2 280 1.6E-98 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 20 109 2.3E-26 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 SUPERFAMILY SSF54675 5 110 1.06E-30 T 29-03-2018 A616_RS00865 265e3f596de66b272e2c3d02f9c16ef1 282 SUPERFAMILY SSF51690 111 277 1.26E-61 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A616_RS16555 bc0199b0e8f1d88a14104bd84c5e960a 323 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 2 316 6.5E-136 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS16555 bc0199b0e8f1d88a14104bd84c5e960a 323 Pfam PF00268 Ribonucleotide reductase, small chain 4 277 3.7E-77 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16555 bc0199b0e8f1d88a14104bd84c5e960a 323 PIRSF PIRSF000355 1 312 1.7E-71 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16555 bc0199b0e8f1d88a14104bd84c5e960a 323 Gene3D G3DSA:1.10.620.20 1 289 2.7E-67 T 29-03-2018 A616_RS16555 bc0199b0e8f1d88a14104bd84c5e960a 323 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 92 108 - T 29-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS16555 bc0199b0e8f1d88a14104bd84c5e960a 323 SUPERFAMILY SSF47240 2 315 1.44E-84 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 Pfam PF01546 Peptidase family M20/M25/M40 75 374 7.5E-23 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 Gene3D G3DSA:3.40.630.10 1 261 3.5E-52 T 29-03-2018 A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 365 2.3E-85 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 SUPERFAMILY SSF53187 5 191 1.02E-58 T 29-03-2018 A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 SUPERFAMILY SSF53187 290 377 1.02E-58 T 29-03-2018 A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 Pfam PF07687 Peptidase dimerisation domain 183 270 2.1E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 SUPERFAMILY SSF55031 181 282 1.2E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 Gene3D G3DSA:3.40.630.10 262 380 1.5E-12 T 29-03-2018 A616_RS26790 fbf0972882c2e36a02aa24e7a11022dd 380 PIRSF PIRSF005962 3 380 1.3E-91 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS29685 8455ecba9cf029b1b836279a03e09f1a 407 SUPERFAMILY SSF53756 98 401 2.79E-40 T 29-03-2018 A616_RS29685 8455ecba9cf029b1b836279a03e09f1a 407 SUPERFAMILY SSF53756 2 68 2.79E-40 T 29-03-2018 A616_RS29685 8455ecba9cf029b1b836279a03e09f1a 407 Gene3D G3DSA:3.40.50.2000 208 386 3.8E-19 T 29-03-2018 A616_RS29685 8455ecba9cf029b1b836279a03e09f1a 407 Pfam PF13692 Glycosyl transferases group 1 237 369 2.0E-9 T 29-03-2018 A616_RS29685 8455ecba9cf029b1b836279a03e09f1a 407 Pfam PF13579 Glycosyl transferase 4-like domain 21 194 9.1E-13 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS29685 8455ecba9cf029b1b836279a03e09f1a 407 Gene3D G3DSA:3.40.50.2000 2 207 3.5E-10 T 29-03-2018 A616_RS19180 e4eb3b411a0c55e69c44cc3890ac1de7 315 SUPERFAMILY SSF53807 39 307 3.81E-61 T 29-03-2018 A616_RS19180 e4eb3b411a0c55e69c44cc3890ac1de7 315 Gene3D G3DSA:3.40.50.1980 25 151 5.1E-28 T 29-03-2018 A616_RS19180 e4eb3b411a0c55e69c44cc3890ac1de7 315 Pfam PF01497 Periplasmic binding protein 70 287 6.1E-29 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS19180 e4eb3b411a0c55e69c44cc3890ac1de7 315 Gene3D G3DSA:3.40.50.1980 152 315 1.2E-33 T 29-03-2018 A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 Gene3D G3DSA:3.40.50.1000 72 180 2.2E-35 T 29-03-2018 IPR023214 HAD-like domain A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 253 2.1E-96 T 29-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 Pfam PF13242 HAD-hyrolase-like 179 252 7.8E-20 T 29-03-2018 A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 107 8.5E-27 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 SUPERFAMILY SSF56784 4 253 8.41E-70 T 29-03-2018 IPR023214 HAD-like domain A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 PIRSF PIRSF000915 1 254 2.4E-63 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A616_RS26430 9c75144ec64ccd47a7ee582db1f0a838 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 229 2.7E-47 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A616_RS30970 a849f0b01fb1148beeb1e2154e6783b6 208 Pfam PF08241 Methyltransferase domain 44 143 4.8E-17 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS30970 a849f0b01fb1148beeb1e2154e6783b6 208 SUPERFAMILY SSF53335 25 188 6.39E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS30970 a849f0b01fb1148beeb1e2154e6783b6 208 Gene3D G3DSA:3.40.50.150 10 200 3.8E-28 T 29-03-2018 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 SUPERFAMILY SSF50249 574 672 1.44E-35 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS00620 19fba8965b661be365c1e48a92c42489 675 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 23 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 481 1.1E-171 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Pfam PF01588 Putative tRNA binding domain 581 672 3.7E-30 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 542 674 1.7E-43 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 SUPERFAMILY SSF52374 2 354 3.22E-110 T 29-03-2018 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Gene3D G3DSA:2.40.50.140 567 675 8.8E-33 T 29-03-2018 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 SUPERFAMILY SSF47323 352 513 1.07E-42 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Gene3D G3DSA:3.40.50.620 2 347 3.2E-95 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Pfam PF09334 tRNA synthetases class I (M) 5 363 1.5E-116 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Pfam PF08264 Anticodon-binding domain of tRNA 394 483 4.6E-6 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 512 50.328 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 2.7E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 351 362 2.7E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 2.7E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 2.7E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 2.7E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 274 2.7E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A616_RS00620 19fba8965b661be365c1e48a92c42489 675 Gene3D G3DSA:1.10.730.10 348 515 1.2E-41 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 SUPERFAMILY SSF46785 9 55 1.75E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 Gene3D G3DSA:3.10.129.10 51 189 5.3E-22 T 29-03-2018 A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 PIRSF PIRSF037733 4 192 3.8E-79 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 Pfam PF08220 DeoR-like helix-turn-helix domain 12 45 1.8E-4 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 Hamap MF_01814 Transcription factor FapR [fapR]. 5 189 34.329 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 Gene3D G3DSA:1.10.10.10 6 50 5.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 Pfam PF01575 MaoC like domain 104 171 1.8E-4 T 29-03-2018 IPR002539 MaoC-like domain A616_RS20305 6fba9c5c5684241d8db1eb759ae05373 196 SUPERFAMILY SSF54637 77 183 9.84E-23 T 29-03-2018 IPR029069 HotDog domain A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Gene3D G3DSA:1.10.8.60 305 376 1.4E-21 T 29-03-2018 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Gene3D G3DSA:3.30.450.20 5 139 7.4E-14 T 29-03-2018 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 SUPERFAMILY SSF55785 7 98 1.26E-10 T 29-03-2018 IPR000014 PAS domain A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 SUPERFAMILY SSF52540 130 372 3.51E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Gene3D G3DSA:3.40.50.300 140 304 5.0E-27 T 29-03-2018 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Pfam PF00158 Sigma-54 interaction domain 131 298 1.1E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Pfam PF00989 PAS fold 6 64 7.7E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 SUPERFAMILY SSF46689 345 429 5.97E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 SMART SM00382 151 299 8.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 395 412 1.0E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 412 432 1.0E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Pfam PF02954 Bacterial regulatory protein, Fis family 390 429 2.8E-15 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 218 233 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 345 354 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 155 168 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 SMART SM00091 5 70 1.3E-6 T 29-03-2018 IPR000014 PAS domain A616_RS14285 b837336c28a2f8a27eb5f6d82ef2d5a3 432 Gene3D G3DSA:1.10.10.60 377 428 5.7E-15 T 29-03-2018 A616_RS15830 b5861dfe08ca7619a3da48daf4e2d3dd 399 SUPERFAMILY SSF51905 121 261 1.94E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15830 b5861dfe08ca7619a3da48daf4e2d3dd 399 Gene3D G3DSA:3.50.50.60 130 261 3.8E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15830 b5861dfe08ca7619a3da48daf4e2d3dd 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 129 9.9E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15830 b5861dfe08ca7619a3da48daf4e2d3dd 399 Gene3D G3DSA:3.50.50.60 7 129 5.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS15830 b5861dfe08ca7619a3da48daf4e2d3dd 399 SUPERFAMILY SSF51905 6 154 7.92E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS24215 02129311a13711786259690466dd2142 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 363 5.8E-74 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS24215 02129311a13711786259690466dd2142 368 Pfam PF03845 Spore germination protein 11 330 6.1E-68 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS31225 37d1aaee21d137d7fdf59a47d29479b3 208 Gene3D G3DSA:2.60.120.10 8 152 3.9E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS31225 37d1aaee21d137d7fdf59a47d29479b3 208 SUPERFAMILY SSF51182 9 107 1.36E-12 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS31225 37d1aaee21d137d7fdf59a47d29479b3 208 Pfam PF07883 Cupin domain 36 97 1.6E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS05960 e8ee0667f787b51863c190cac00f86e8 212 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 179 1.6E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05960 e8ee0667f787b51863c190cac00f86e8 212 Gene3D G3DSA:3.40.50.1000 1 205 1.6E-38 T 29-03-2018 IPR023214 HAD-like domain A616_RS05960 e8ee0667f787b51863c190cac00f86e8 212 SUPERFAMILY SSF56784 1 210 1.32E-48 T 29-03-2018 IPR023214 HAD-like domain A616_RS05960 e8ee0667f787b51863c190cac00f86e8 212 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 173 4.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS05960 e8ee0667f787b51863c190cac00f86e8 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 179 1.1E-45 T 29-03-2018 IPR023214 HAD-like domain A616_RS22390 febbe841a2625c2f3b59d88317d846ce 262 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 64 252 6.4E-28 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS22390 febbe841a2625c2f3b59d88317d846ce 262 Gene3D G3DSA:3.40.50.1110 56 262 1.4E-39 T 29-03-2018 A616_RS22390 febbe841a2625c2f3b59d88317d846ce 262 SUPERFAMILY SSF52266 59 261 1.38E-38 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 Gene3D G3DSA:1.10.287.130 342 414 4.8E-11 T 29-03-2018 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 Gene3D G3DSA:3.30.565.10 415 578 2.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 SUPERFAMILY SSF47384 342 419 3.92E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 413 2.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 SUPERFAMILY SSF55874 410 576 9.69E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 467 576 9.7E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 518 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 575 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 532 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 556 1.6E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 SMART SM00388 352 420 2.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05365 e7fcee998def57e240b03878d9ac3df4 579 SMART SM00387 466 578 3.7E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 ProSitePatterns PS00622 LuxR-type HTH domain signature. 516 543 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 Gene3D G3DSA:1.10.10.10 169 557 1.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 SMART SM00421 499 556 8.0E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 Pfam PF00196 Bacterial regulatory proteins, luxR family 501 554 8.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 532 544 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 502 516 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 516 532 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15930 b14ca0034af4b3acf571abce9205f61a 558 SUPERFAMILY SSF46894 495 556 2.62E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SUPERFAMILY SSF55048 451 514 1.44E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Gene3D G3DSA:3.20.20.70 640 1078 1.7E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Gene3D G3DSA:3.40.366.10 4 316 6.9E-57 T 29-03-2018 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 335 640 4.2E-23 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 305 4.5E-33 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SUPERFAMILY SSF51395 594 902 2.2E-26 T 29-03-2018 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Pfam PF00698 Acyl transferase domain 6 313 2.2E-33 T 29-03-2018 IPR014043 Acyl transferase A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Pfam PF00698 Acyl transferase domain 333 605 2.0E-33 T 29-03-2018 IPR014043 Acyl transferase A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Pfam PF03060 Nitronate monooxygenase 655 920 9.6E-9 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SUPERFAMILY SSF52151 332 447 2.56E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SUPERFAMILY SSF52151 511 621 2.56E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Gene3D G3DSA:3.40.366.10 326 489 1.3E-38 T 29-03-2018 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 641 1079 2.9E-203 T 29-03-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SUPERFAMILY SSF52151 198 290 1.83E-49 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 SUPERFAMILY SSF52151 5 135 1.83E-49 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 331 611 9.7E-112 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A616_RS22065 b5c3c7ccd865abbc9f8b1e77849577c6 1088 Gene3D G3DSA:3.40.366.10 490 615 1.1E-21 T 29-03-2018 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Gene3D G3DSA:3.40.960.10 1560 1667 1.6E-29 T 29-03-2018 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Gene3D G3DSA:3.40.50.300 1346 1538 2.3E-15 T 29-03-2018 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 SMART SM00952 1606 1662 1.4E-6 T 29-03-2018 IPR013584 RAP domain A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Pfam PF13086 AAA domain 1254 1296 3.3E-7 T 29-03-2018 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Pfam PF13086 AAA domain 314 377 1.2E-6 T 29-03-2018 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 SUPERFAMILY SSF52980 1557 1664 2.63E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Pfam PF13195 Protein of unknown function (DUF4011) 27 203 5.9E-32 T 29-03-2018 IPR025103 Protein of unknown function DUF4011 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Pfam PF13087 AAA domain 1332 1514 3.8E-15 T 29-03-2018 A616_RS06940 6955da00c48004845117bcc4e160f342 1667 SUPERFAMILY SSF52540 1229 1513 8.87E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06940 6955da00c48004845117bcc4e160f342 1667 SUPERFAMILY SSF52540 313 379 8.87E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06940 6955da00c48004845117bcc4e160f342 1667 Gene3D G3DSA:3.40.50.300 307 1345 1.5E-39 T 29-03-2018 A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 324 6.4E-54 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 32 332 32.947 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 Pfam PF03193 RsgA GTPase 95 269 6.8E-52 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 Gene3D G3DSA:2.40.50.140 26 94 2.7E-7 T 29-03-2018 A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 SUPERFAMILY SSF52540 112 329 4.59E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 Gene3D G3DSA:1.10.40.50 271 337 5.1E-20 T 29-03-2018 A616_RS24305 b0c3518b7af9657962c499e33cd703c4 361 Gene3D G3DSA:3.40.50.300 111 268 4.5E-25 T 29-03-2018 A616_RS19050 67e67d640a9b9a67c3f37ed9ee83423b 100 SUPERFAMILY SSF89360 2 93 1.33E-13 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS19050 67e67d640a9b9a67c3f37ed9ee83423b 100 Gene3D G3DSA:2.60.300.12 1 98 2.8E-13 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS26405 84262e2100fb8d33e94db6aaa40e14b2 89 Pfam PF01106 NifU-like domain 21 86 1.3E-29 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A616_RS26405 84262e2100fb8d33e94db6aaa40e14b2 89 SUPERFAMILY SSF117916 14 88 1.96E-27 T 29-03-2018 IPR034904 Fe-S cluster assembly domain A616_RS26405 84262e2100fb8d33e94db6aaa40e14b2 89 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 25 88 2.0E-26 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A616_RS26405 84262e2100fb8d33e94db6aaa40e14b2 89 Gene3D G3DSA:3.30.300.130 12 89 4.9E-30 T 29-03-2018 IPR034904 Fe-S cluster assembly domain A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 SUPERFAMILY SSF56300 2 270 3.07E-64 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 Pfam PF00149 Calcineurin-like phosphoesterase 8 207 3.9E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 Gene3D G3DSA:3.60.21.10 1 288 7.1E-54 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 Gene3D G3DSA:3.90.780.10 289 484 5.1E-32 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 PRINTS PR01607 Apyrase family signature 331 354 5.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 PRINTS PR01607 Apyrase family signature 190 213 5.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 PRINTS PR01607 Apyrase family signature 5 23 5.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 PRINTS PR01607 Apyrase family signature 171 188 5.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 PRINTS PR01607 Apyrase family signature 218 238 5.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 PRINTS PR01607 Apyrase family signature 413 432 5.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 SUPERFAMILY SSF55816 280 475 1.1E-29 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 ProSitePatterns PS00785 5'-nucleotidase signature 1. 7 19 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS26645 2991379a2f8b06bd554f6394d900302f 484 Pfam PF02872 5'-nucleotidase, C-terminal domain 293 426 1.5E-17 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS00720 abd919aa1bcd1aba346b64c7f72b1e62 554 Pfam PF01943 Polysaccharide biosynthesis protein 11 316 1.1E-34 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A616_RS00720 abd919aa1bcd1aba346b64c7f72b1e62 554 PIRSF PIRSF038958 5 534 3.7E-113 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A616_RS00720 abd919aa1bcd1aba346b64c7f72b1e62 554 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 367 516 8.0E-32 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A616_RS05110 dedefc7ee1e17fc1f2da70d49534a2b2 132 Pfam PF08868 YugN-like family 3 131 4.0E-45 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS05110 dedefc7ee1e17fc1f2da70d49534a2b2 132 SUPERFAMILY SSF160755 1 131 1.83E-29 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS05110 dedefc7ee1e17fc1f2da70d49534a2b2 132 Gene3D G3DSA:3.30.310.100 1 115 3.8E-35 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 Gene3D G3DSA:2.60.120.10 1 139 7.8E-29 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 Gene3D G3DSA:1.10.10.10 140 225 2.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 SMART SM00100 12 130 8.5E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 SMART SM00419 170 218 1.9E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 Pfam PF13545 Crp-like helix-turn-helix domain 151 224 2.2E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 SUPERFAMILY SSF46785 149 225 1.18E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 Pfam PF00027 Cyclic nucleotide-binding domain 33 115 7.8E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS06570 c2034aaa02d438153355d6cc46b8af8e 225 SUPERFAMILY SSF51206 6 144 9.17E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS11960 827db424af07d62715202bf8570c908b 334 Pfam PF01545 Cation efflux family 26 218 4.4E-50 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS11960 827db424af07d62715202bf8570c908b 334 Gene3D G3DSA:3.30.70.1350 220 300 6.8E-13 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A616_RS11960 827db424af07d62715202bf8570c908b 334 SUPERFAMILY SSF160240 222 295 7.98E-9 T 29-03-2018 A616_RS11960 827db424af07d62715202bf8570c908b 334 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 297 4.6E-93 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS11960 827db424af07d62715202bf8570c908b 334 SUPERFAMILY SSF161111 22 219 4.97E-58 T 29-03-2018 A616_RS11960 827db424af07d62715202bf8570c908b 334 Gene3D G3DSA:1.20.1510.10 21 218 1.7E-58 T 29-03-2018 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 Pfam PF02675 S-adenosylmethionine decarboxylase 39 175 2.0E-29 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 Gene3D G3DSA:3.60.90.10 34 195 1.8E-42 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 9 267 2.0E-135 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 269 158.017 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 PIRSF PIRSF001356 3 269 9.0E-132 T 29-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 SUPERFAMILY SSF56276 118 179 1.37E-23 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A616_RS04670 96e12b318a90ad3b0da39b57673caf98 269 SUPERFAMILY SSF56276 48 89 1.37E-23 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A616_RS19320 059655a3f3d681e8458c664f351f35a6 41 Pfam PF01844 HNH endonuclease 2 39 7.6E-6 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A616_RS19320 059655a3f3d681e8458c664f351f35a6 41 Gene3D G3DSA:3.40.1800.10 1 39 2.4E-4 T 29-03-2018 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 Pfam PF01019 Gamma-glutamyltranspeptidase 53 567 7.1E-154 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 38 564 2.7E-145 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 SUPERFAMILY SSF56235 26 572 1.93E-169 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 384 402 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 439 454 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 426 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 155 174 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 261 277 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 59 84 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS30460 05d4e7fc9db3f7219436f9c0ef52954f 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 290 309 3.8E-34 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 A616_RS03195 f6ddf28e026ab6982665abaf9277ac3b 498 Pfam PF01433 Peptidase family M1 domain 253 473 1.7E-18 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A616_RS03195 f6ddf28e026ab6982665abaf9277ac3b 498 SUPERFAMILY SSF55486 251 474 5.13E-37 T 29-03-2018 A616_RS03195 f6ddf28e026ab6982665abaf9277ac3b 498 Gene3D G3DSA:2.60.40.1730 33 224 2.4E-4 T 29-03-2018 A616_RS03195 f6ddf28e026ab6982665abaf9277ac3b 498 Gene3D G3DSA:1.10.390.10 319 476 5.1E-27 T 29-03-2018 A616_RS03985 8b2d44465f0a0c7b1733592114b774ed 355 Gene3D G3DSA:3.10.570.10 40 354 7.9E-82 T 29-03-2018 A616_RS03985 8b2d44465f0a0c7b1733592114b774ed 355 PIRSF PIRSF012509 8 354 7.6E-71 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 A616_RS03985 8b2d44465f0a0c7b1733592114b774ed 355 Pfam PF07537 CamS sex pheromone cAM373 precursor 59 342 4.9E-62 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 A616_RS18885 0115ee572561672d71f2633860e11f40 310 Pfam PF00005 ABC transporter 18 161 1.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS18885 0115ee572561672d71f2633860e11f40 310 Gene3D G3DSA:3.40.50.300 1 283 2.8E-63 T 29-03-2018 A616_RS18885 0115ee572561672d71f2633860e11f40 310 SUPERFAMILY SSF52540 2 224 1.3E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18885 0115ee572561672d71f2633860e11f40 310 SMART SM00382 27 210 1.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 366 380 2.4E-22 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 443 456 2.4E-22 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 310 332 2.4E-22 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 84 103 2.4E-22 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 381 395 2.4E-22 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 48 485 8.5E-121 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 510 961 3.6E-111 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 74 466 6.4E-106 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 537 941 1.5E-97 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 SUPERFAMILY SSF56601 508 961 2.4E-92 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 Gene3D G3DSA:3.40.710.10 48 481 6.8E-38 T 29-03-2018 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 Gene3D G3DSA:3.40.710.10 503 964 1.6E-36 T 29-03-2018 A616_RS17940 065eb13a1d1b6eda51381524f92eb09e 964 SUPERFAMILY SSF56601 50 481 2.23E-94 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS07215 2a9c6e6e7cf53f5d18ccd54b41ea1280 241 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS07215 2a9c6e6e7cf53f5d18ccd54b41ea1280 241 SMART SM00382 30 212 4.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS07215 2a9c6e6e7cf53f5d18ccd54b41ea1280 241 Pfam PF00005 ABC transporter 23 161 4.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS07215 2a9c6e6e7cf53f5d18ccd54b41ea1280 241 Gene3D G3DSA:3.40.50.300 3 239 2.6E-63 T 29-03-2018 A616_RS07215 2a9c6e6e7cf53f5d18ccd54b41ea1280 241 SUPERFAMILY SSF52540 6 227 5.54E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 Gene3D G3DSA:1.20.1440.10 29 198 2.0E-4 T 29-03-2018 A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 488 4.9E-111 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 6.2E-8 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 6.2E-8 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 Pfam PF00460 Flagella basal body rod protein 8 37 4.2E-7 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 SUPERFAMILY SSF64518 154 488 1.44E-21 T 29-03-2018 A616_RS29575 c311d91d3edcbdf34d975b4499ba3300 495 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 411 488 6.0E-14 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A616_RS00225 f327cb520905515ac916ab1896b1618a 191 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 29-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00225 f327cb520905515ac916ab1896b1618a 191 Gene3D G3DSA:3.40.50.880 1 191 3.6E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS00225 f327cb520905515ac916ab1896b1618a 191 SUPERFAMILY SSF52317 2 188 9.17E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS00225 f327cb520905515ac916ab1896b1618a 191 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 184 1.3E-75 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00225 f327cb520905515ac916ab1896b1618a 191 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 185 37.696 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00225 f327cb520905515ac916ab1896b1618a 191 Pfam PF01174 SNO glutamine amidotransferase family 5 187 1.0E-65 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00225 f327cb520905515ac916ab1896b1618a 191 PIRSF PIRSF005639 1 190 6.1E-73 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 Gene3D G3DSA:3.40.50.300 1 283 1.0E-58 T 29-03-2018 A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 SUPERFAMILY SSF52540 295 524 6.89E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 Pfam PF00005 ABC transporter 336 466 3.9E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 Pfam PF00005 ABC transporter 18 184 8.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 Pfam PF12848 ABC transporter 224 308 7.4E-20 T 29-03-2018 IPR032781 ABC-transporter extension domain A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 SMART SM00382 344 511 4.8E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 SMART SM00382 26 238 3.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 Gene3D G3DSA:3.40.50.300 284 535 4.5E-41 T 29-03-2018 A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 SUPERFAMILY SSF52540 125 257 7.16E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14225 4b188689d7aae2cbb5a6f5501cf0cc69 537 SUPERFAMILY SSF52540 2 92 7.16E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31490 0d49957680901ef0b446123c0ade228a 476 Pfam PF01551 Peptidase family M23 377 465 5.6E-27 T 29-03-2018 IPR016047 Peptidase M23 A616_RS31490 0d49957680901ef0b446123c0ade228a 476 SUPERFAMILY SSF51261 375 469 2.62E-34 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS31490 0d49957680901ef0b446123c0ade228a 476 Gene3D G3DSA:3.30.2010.10 149 238 1.6E-7 T 29-03-2018 A616_RS31490 0d49957680901ef0b446123c0ade228a 476 Pfam PF05569 BlaR1 peptidase M56 18 317 8.6E-62 T 29-03-2018 IPR008756 Peptidase M56 A616_RS31490 0d49957680901ef0b446123c0ade228a 476 Gene3D G3DSA:2.70.70.10 351 476 2.8E-32 T 29-03-2018 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 SUPERFAMILY SSF111369 136 168 9.29E-17 T 29-03-2018 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 SUPERFAMILY SSF111369 202 334 9.29E-17 T 29-03-2018 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 SUPERFAMILY SSF111369 55 133 5.62E-11 T 29-03-2018 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 329 8.2E-25 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 200 406 2.5E-46 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 Gene3D G3DSA:1.20.1600.10 196 374 4.4E-17 T 29-03-2018 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 Gene3D G3DSA:2.40.50.100 62 132 7.5E-14 T 29-03-2018 A616_RS08045 e9ac57e6d99646d9e59361c430f61b08 409 Gene3D G3DSA:1.10.287.470 133 194 2.4E-10 T 29-03-2018 A616_RS30960 8a4ebe8c25691589d021e477b1d6ba01 116 Pfam PF05610 Protein of unknown function (DUF779) 16 109 5.1E-51 T 29-03-2018 IPR008497 Protein of unknown function DUF779 A616_RS30960 8a4ebe8c25691589d021e477b1d6ba01 116 PIRSF PIRSF009151 1 116 2.2E-60 T 29-03-2018 IPR008497 Protein of unknown function DUF779 A616_RS03685 58910c9a85f0ea1f6a5e98bc792f6e96 280 SUPERFAMILY SSF161098 4 271 3.01E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS03685 58910c9a85f0ea1f6a5e98bc792f6e96 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 266 4.0E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS03685 58910c9a85f0ea1f6a5e98bc792f6e96 280 Gene3D G3DSA:1.10.3720.10 6 277 2.1E-46 T 29-03-2018 A616_RS32045 6e8c848dec7ed3e82a866f748c45be14 112 SUPERFAMILY SSF51182 2 107 8.45E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS32045 6e8c848dec7ed3e82a866f748c45be14 112 Gene3D G3DSA:2.60.120.10 1 101 1.4E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS32045 6e8c848dec7ed3e82a866f748c45be14 112 Pfam PF07883 Cupin domain 39 87 3.1E-8 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 Gene3D G3DSA:2.40.240.10 2 92 2.3E-24 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 175 1.0E-17 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 177 24.974 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 SUPERFAMILY SSF50715 9 174 2.09E-45 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 Pfam PF01386 Ribosomal L25p family 4 90 4.9E-21 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 174 1.8E-40 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 Gene3D G3DSA:2.170.120.20 97 181 4.2E-19 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain A616_RS00690 e4b09631b374370c1c3f6279eaac1136 202 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 91 5.0E-14 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 Gene3D G3DSA:3.40.50.970 1 181 1.0E-52 T 29-03-2018 A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 320 5.1E-31 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 Gene3D G3DSA:3.40.50.1220 182 336 3.3E-36 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 SUPERFAMILY SSF52518 354 523 3.49E-43 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 Gene3D G3DSA:3.40.50.970 337 524 7.1E-29 T 29-03-2018 A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 SUPERFAMILY SSF52518 1 168 1.05E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 518 2.0E-28 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 165 5.3E-57 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 SUPERFAMILY SSF52467 153 337 1.0E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS07590 32cd602ea81aa31a87b1a5deca85f108 530 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 411 430 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A616_RS04630 8ec6bcc9aaac637274fcc3bde15dc96a 296 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 71 4.0E-12 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS04630 8ec6bcc9aaac637274fcc3bde15dc96a 296 SUPERFAMILY SSF161098 89 276 5.63E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS04630 8ec6bcc9aaac637274fcc3bde15dc96a 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 295 3.6E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS04630 8ec6bcc9aaac637274fcc3bde15dc96a 296 Gene3D G3DSA:1.10.3720.10 19 284 4.1E-46 T 29-03-2018 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 SUPERFAMILY SSF51230 4 83 5.1E-24 T 29-03-2018 IPR011053 Single hybrid motif A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Gene3D G3DSA:4.10.320.10 147 202 7.2E-19 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 233 460 2.7E-92 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 SUPERFAMILY SSF47005 144 187 1.2E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Pfam PF02817 e3 binding domain 148 182 5.6E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Pfam PF00364 Biotin-requiring enzyme 5 76 1.9E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Gene3D G3DSA:3.30.559.10 215 461 1.8E-93 T 29-03-2018 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 SUPERFAMILY SSF52777 224 460 8.9E-92 T 29-03-2018 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Gene3D G3DSA:3.90.1170.30 47 146 0.022 T 29-03-2018 A616_RS19015 e359194567e70f0f2a81f1ad48c6b1f2 463 Gene3D G3DSA:3.90.1170.30 2 46 1.4E-13 T 29-03-2018 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 SUPERFAMILY SSF47203 256 409 1.61E-52 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 Gene3D G3DSA:1.10.540.10 1 145 6.2E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 SUPERFAMILY SSF56645 3 266 1.57E-45 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 407 1.3E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 244 3.6E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 143 3.1E-4 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 Gene3D G3DSA:2.40.110.10 147 252 4.7E-29 T 29-03-2018 A616_RS15405 58edb5e5af8df8ad55751e5e191a252b 414 Gene3D G3DSA:1.20.140.10 253 414 6.2E-50 T 29-03-2018 A616_RS24815 52d81b391f6198b01c4dcb026ca313f4 212 SUPERFAMILY SSF52499 7 206 5.49E-49 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS24815 52d81b391f6198b01c4dcb026ca313f4 212 Pfam PF00857 Isochorismatase family 14 166 2.9E-26 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS24815 52d81b391f6198b01c4dcb026ca313f4 212 Gene3D G3DSA:3.40.50.850 2 208 9.2E-36 T 29-03-2018 A616_RS26475 4fec414a714ce0dac068875b308e2812 342 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 17 325 1.4E-11 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A616_RS10220 7fd2c7622c4562feb72727652c309124 594 SUPERFAMILY SSF52540 340 589 1.3E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10220 7fd2c7622c4562feb72727652c309124 594 Gene3D G3DSA:1.20.1560.10 2 333 2.1E-27 T 29-03-2018 A616_RS10220 7fd2c7622c4562feb72727652c309124 594 SMART SM00382 374 565 3.5E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS10220 7fd2c7622c4562feb72727652c309124 594 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS10220 7fd2c7622c4562feb72727652c309124 594 SUPERFAMILY SSF90123 11 310 4.19E-24 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS10220 7fd2c7622c4562feb72727652c309124 594 Gene3D G3DSA:3.40.50.300 334 592 3.5E-69 T 29-03-2018 A616_RS10220 7fd2c7622c4562feb72727652c309124 594 Pfam PF00005 ABC transporter 366 519 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 29 497 6.6E-101 T 29-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 Gene3D G3DSA:3.30.300.30 403 508 1.8E-29 T 29-03-2018 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 Pfam PF00501 AMP-binding enzyme 9 408 8.1E-109 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 Gene3D G3DSA:2.30.38.10 320 401 3.0E-28 T 29-03-2018 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 SUPERFAMILY SSF56801 6 503 3.66E-157 T 29-03-2018 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 492 7.3E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 Gene3D G3DSA:3.40.50.980 169 319 3.9E-45 T 29-03-2018 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 Gene3D G3DSA:3.40.50.980 2 168 5.4E-42 T 29-03-2018 A616_RS14385 14ed2f135725017e3dce664644e68f2d 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS19910 8f6e9eecaf576341fbe8051aafd5f364 161 SUPERFAMILY SSF64438 3 159 2.01E-48 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A616_RS19910 8f6e9eecaf576341fbe8051aafd5f364 161 Pfam PF03975 CheD chemotactic sensory transduction 47 153 1.6E-34 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A616_RS19910 8f6e9eecaf576341fbe8051aafd5f364 161 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 5 157 25.632 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 Gene3D G3DSA:2.40.50.140 1 66 2.6E-30 T 29-03-2018 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 PIRSF PIRSF002599 1 66 3.5E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site A616_RS09625 5c404abb16b73902160da9704c4e7009 66 PRINTS PR00050 Cold shock protein signature 39 57 2.8E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 PRINTS PR00050 Cold shock protein signature 24 33 2.8E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 SMART SM00357 3 66 4.0E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.3E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS09625 5c404abb16b73902160da9704c4e7009 66 SUPERFAMILY SSF50249 1 65 1.11E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 2.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 333 2.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 2.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 Gene3D G3DSA:3.30.565.10 243 382 7.4E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 374 2.9E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 PIRSF PIRSF037431 59 382 4.2E-106 T 29-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 SMART SM00304 103 155 0.0014 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 SUPERFAMILY SSF55874 250 374 2.49E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 Pfam PF07730 Histidine kinase 179 246 2.8E-19 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS05710 b4ce4d632efe51874423e1ed941bf459 382 SMART SM00387 283 376 2.6E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 SMART SM00342 410 493 1.1E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 SUPERFAMILY SSF46689 446 495 5.82E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 Gene3D G3DSA:3.40.50.2300 1 132 1.6E-10 T 29-03-2018 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 Pfam PF12833 Helix-turn-helix domain 417 494 1.5E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 Gene3D G3DSA:2.60.120.10 133 448 7.6E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 SUPERFAMILY SSF52172 1 126 1.14E-11 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 447 489 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 462 477 9.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 477 493 9.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS23315 145e70a7340eb20c5b849270c99b38d0 498 Gene3D G3DSA:1.10.10.60 449 498 1.3E-15 T 29-03-2018 A616_RS23040 b2cb6dedd3d682b48d46ba14319065b1 106 Gene3D G3DSA:1.10.10.10 18 106 4.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23040 b2cb6dedd3d682b48d46ba14319065b1 106 Pfam PF01638 HxlR-like helix-turn-helix 20 106 7.1E-33 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS23040 b2cb6dedd3d682b48d46ba14319065b1 106 SUPERFAMILY SSF46785 10 106 9.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26425 1ad3b31313f5b683e1166d4f1864a873 171 PIRSF PIRSF019587 7 168 2.5E-68 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase A616_RS26425 1ad3b31313f5b683e1166d4f1864a873 171 Gene3D G3DSA:1.10.3760.10 3 171 1.4E-56 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A616_RS26425 1ad3b31313f5b683e1166d4f1864a873 171 SUPERFAMILY SSF101307 13 162 7.59E-51 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A616_RS26425 1ad3b31313f5b683e1166d4f1864a873 171 Pfam PF04608 Phosphatidylglycerophosphatase A 16 159 2.1E-16 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A616_RS31420 5e501da78d88a9ea8df1ce3daa67b41d 155 Pfam PF02566 OsmC-like protein 37 140 1.1E-24 T 29-03-2018 IPR003718 OsmC/Ohr family A616_RS31420 5e501da78d88a9ea8df1ce3daa67b41d 155 Gene3D G3DSA:3.30.300.20 2 144 2.0E-34 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS31420 5e501da78d88a9ea8df1ce3daa67b41d 155 SUPERFAMILY SSF82784 3 140 1.26E-43 T 29-03-2018 IPR003718 OsmC/Ohr family A616_RS01105 89a985c8c93417144338bae03537e838 300 Gene3D G3DSA:3.10.50.40 151 275 1.5E-25 T 29-03-2018 A616_RS01105 89a985c8c93417144338bae03537e838 300 SUPERFAMILY SSF54534 162 255 3.34E-18 T 29-03-2018 A616_RS01105 89a985c8c93417144338bae03537e838 300 Gene3D G3DSA:1.10.4030.10 29 140 1.8E-13 T 29-03-2018 A616_RS01105 89a985c8c93417144338bae03537e838 300 Pfam PF13624 SurA N-terminal domain 7 133 2.9E-10 T 29-03-2018 A616_RS01105 89a985c8c93417144338bae03537e838 300 SUPERFAMILY SSF109998 34 189 7.45E-24 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS01105 89a985c8c93417144338bae03537e838 300 Pfam PF13145 PPIC-type PPIASE domain 140 265 8.4E-18 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 A616_RS25395 ea94d35424b299eee7f54b3376d58190 112 Pfam PF12788 YmaF family 20 107 2.0E-21 T 29-03-2018 IPR024307 YmaF A616_RS31125 a07cb1d37054c1195e813842b853df98 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 266 2.5E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31125 a07cb1d37054c1195e813842b853df98 273 Gene3D G3DSA:1.10.3720.10 5 273 3.8E-51 T 29-03-2018 A616_RS31125 a07cb1d37054c1195e813842b853df98 273 SUPERFAMILY SSF161098 5 265 4.06E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09675 57ce3a9cf7684cbf58258125962a6501 283 Gene3D G3DSA:3.40.50.150 22 148 4.3E-27 T 29-03-2018 A616_RS09675 57ce3a9cf7684cbf58258125962a6501 283 Gene3D G3DSA:3.40.50.150 149 216 1.9E-4 T 29-03-2018 A616_RS09675 57ce3a9cf7684cbf58258125962a6501 283 Pfam PF08241 Methyltransferase domain 63 161 5.9E-24 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS09675 57ce3a9cf7684cbf58258125962a6501 283 SUPERFAMILY SSF53335 28 198 1.37E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 SUPERFAMILY SSF54001 10 258 1.52E-56 T 29-03-2018 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 Gene3D G3DSA:3.30.2140.10 2 141 2.9E-26 T 29-03-2018 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 4.8E-14 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 4.8E-14 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 4.8E-14 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 103 128 4.8E-14 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 PRINTS PR01543 Arylamine N-acetyltransferase signature 240 258 4.8E-14 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 Gene3D G3DSA:3.30.2140.10 142 258 3.1E-7 T 29-03-2018 A616_RS31500 dcf5b3c097efc9a16b38ca7f2034a747 258 Pfam PF00797 N-acetyltransferase 22 258 1.4E-44 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 Gene3D G3DSA:3.40.50.2300 1 126 8.1E-37 T 29-03-2018 A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 Gene3D G3DSA:1.10.10.10 127 228 1.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 SMART SM00862 147 223 1.1E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 7.2E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 SMART SM00448 2 112 2.0E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07430 1ea98bf5c09f7554c0bed0cfe6ecae40 228 SUPERFAMILY SSF52172 1 175 2.28E-41 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS11390 d124edbd1d226a7e00b4e80bd829e5bf 292 Pfam PF13673 Acetyltransferase (GNAT) domain 54 137 2.1E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS11390 d124edbd1d226a7e00b4e80bd829e5bf 292 SUPERFAMILY SSF55729 14 270 1.3E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11390 d124edbd1d226a7e00b4e80bd829e5bf 292 Gene3D G3DSA:3.40.630.30 140 260 0.0026 T 29-03-2018 A616_RS11390 d124edbd1d226a7e00b4e80bd829e5bf 292 Gene3D G3DSA:3.40.630.30 11 139 3.5E-13 T 29-03-2018 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 SMART SM00864 8 204 0.0013 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 9 168 5.2E-10 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 PRINTS PR01161 Tubulin signature 112 133 8.1E-5 T 29-03-2018 IPR000217 Tubulin GO:0005874|GO:0007017 Reactome: R-HSA-380320 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 PRINTS PR01161 Tubulin signature 56 67 8.1E-5 T 29-03-2018 IPR000217 Tubulin GO:0005874|GO:0007017 Reactome: R-HSA-380320 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 PRINTS PR01161 Tubulin signature 93 111 8.1E-5 T 29-03-2018 IPR000217 Tubulin GO:0005874|GO:0007017 Reactome: R-HSA-380320 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 Gene3D G3DSA:3.40.50.1440 8 221 1.4E-21 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS16960 5511eebf93eda03eeda37b51036f302d 380 SUPERFAMILY SSF52490 6 197 7.06E-24 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS13560 1e5da9ba99f6f87dcccd7ad49e118c37 371 Pfam PF14493 Helix-turn-helix domain 276 363 2.5E-19 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A616_RS13560 1e5da9ba99f6f87dcccd7ad49e118c37 371 Gene3D G3DSA:1.10.10.10 143 314 7.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 250 8.1E-17 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 125 1.0E-18 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Pfam PF00989 PAS fold 131 241 2.7E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Gene3D G3DSA:1.10.287.130 250 318 6.5E-14 T 29-03-2018 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SUPERFAMILY SSF55874 313 471 4.71E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SUPERFAMILY SSF47384 251 320 1.77E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SMART SM00091 130 196 4.0E-9 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SMART SM00091 6 72 4.3E-9 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 2.8E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SUPERFAMILY SSF55785 115 242 6.28E-25 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Gene3D G3DSA:3.30.450.20 3 119 9.9E-22 T 29-03-2018 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 320 1.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Gene3D G3DSA:3.30.565.10 323 476 1.6E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SMART SM00387 364 470 5.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Gene3D G3DSA:3.30.450.20 120 249 6.5E-29 T 29-03-2018 A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 468 2.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SUPERFAMILY SSF55785 11 120 7.85E-17 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 Pfam PF13426 PAS domain 16 117 1.2E-9 T 29-03-2018 IPR000014 PAS domain A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SMART SM00086 77 118 6.6 T 29-03-2018 IPR001610 PAC motif A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SMART SM00086 202 244 0.015 T 29-03-2018 IPR001610 PAC motif A616_RS29385 0034932c5ab26263a0256d95c2f17649 478 SMART SM00388 259 322 2.3E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02420 8cd348f9c0ce6d909bc14e9fc6bd69fa 404 SMART SM00833 261 376 2.9E-51 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS02420 8cd348f9c0ce6d909bc14e9fc6bd69fa 404 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 261 376 4.2E-29 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS02420 8cd348f9c0ce6d909bc14e9fc6bd69fa 404 Gene3D G3DSA:3.30.1220.10 244 377 1.5E-34 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal A616_RS02420 8cd348f9c0ce6d909bc14e9fc6bd69fa 404 Gene3D G3DSA:3.40.50.300 5 233 8.5E-52 T 29-03-2018 A616_RS02420 8cd348f9c0ce6d909bc14e9fc6bd69fa 404 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 9 214 2.2E-55 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A616_RS02420 8cd348f9c0ce6d909bc14e9fc6bd69fa 404 SUPERFAMILY SSF52540 7 305 2.23E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 Gene3D G3DSA:3.40.50.720 1 198 1.1E-21 T 29-03-2018 A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 321 50.559 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 Gene3D G3DSA:3.90.25.10 199 242 1.1E-21 T 29-03-2018 A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 Gene3D G3DSA:3.90.25.10 243 322 5.5E-22 T 29-03-2018 A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 318 4.5E-125 T 29-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 SUPERFAMILY SSF51735 2 316 2.53E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10145 3c6c3ed1e49487a5defcad15e3d97394 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 311 6.7E-119 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13040 43adc373d1b14b6ef1dd3398394d2907 87 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 9 83 8.0E-12 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV A616_RS13040 43adc373d1b14b6ef1dd3398394d2907 87 Pfam PF10942 Protein of unknown function (DUF2619) 13 81 2.5E-30 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 8.8E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 SUPERFAMILY SSF48498 84 186 5.4E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 SUPERFAMILY SSF46689 2 76 1.3E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 Pfam PF13305 WHG domain 92 170 7.6E-8 T 29-03-2018 IPR025996 WHG domain A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS22550 fa7d5652869cc6c476a3c55a1a8ddb66 209 Gene3D G3DSA:1.10.357.10 3 204 2.9E-35 T 29-03-2018 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 Gene3D G3DSA:1.10.601.10 34 131 4.1E-30 T 29-03-2018 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 Pfam PF04545 Sigma-70, region 4 181 234 8.7E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 SUPERFAMILY SSF88946 13 132 4.32E-35 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 9 240 2.0E-131 T 29-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 PIRSF PIRSF000770 10 240 7.1E-75 T 29-03-2018 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 Gene3D G3DSA:1.10.1270.10 154 240 5.1E-22 T 29-03-2018 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 PRINTS PR00046 Major sigma-70 factor signature 185 197 6.3E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 PRINTS PR00046 Major sigma-70 factor signature 87 100 6.3E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 PRINTS PR00046 Major sigma-70 factor signature 206 221 6.3E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 PRINTS PR00046 Major sigma-70 factor signature 221 232 6.3E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 Pfam PF04542 Sigma-70 region 2 63 132 1.9E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 SUPERFAMILY SSF88659 144 238 4.49E-23 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS21245 318efa082816f9410ed9ea65b35010ea 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 235 2.3E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 SUPERFAMILY SSF53335 73 221 8.9E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 SUPERFAMILY SSF53335 256 421 8.9E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 SUPERFAMILY SSF88697 1 71 2.6E-16 T 29-03-2018 IPR015947 PUA-like domain A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 Gene3D G3DSA:2.30.130.10 1 68 2.6E-23 T 29-03-2018 IPR002478 PUA domain GO:0003723 A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 Gene3D G3DSA:3.30.750.80 73 177 2.0E-35 T 29-03-2018 A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 Gene3D G3DSA:3.40.50.150 178 431 5.3E-43 T 29-03-2018 A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 254 398 2.5E-12 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 167 209 8.7E-5 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A616_RS11520 22b27398aed4abd30ff461ac3feb8c4a 431 SMART SM00359 2 87 1.1E-11 T 29-03-2018 IPR002478 PUA domain GO:0003723 A616_RS25675 f57a1d5285feda75515f191af8bd5549 288 SUPERFAMILY SSF51735 2 249 8.19E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS25675 f57a1d5285feda75515f191af8bd5549 288 Pfam PF05368 NmrA-like family 2 221 2.9E-26 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A616_RS25675 f57a1d5285feda75515f191af8bd5549 288 Gene3D G3DSA:3.40.50.720 1 144 5.3E-19 T 29-03-2018 A616_RS25675 f57a1d5285feda75515f191af8bd5549 288 Gene3D G3DSA:3.90.25.10 145 288 6.6E-6 T 29-03-2018 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 SUPERFAMILY SSF53223 20 198 6.08E-67 T 29-03-2018 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 115 128 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 196 427 2.1E-78 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 SMART SM00839 198 427 8.1E-94 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 51 178 9.2E-55 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 229 249 7.9E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 107 121 7.9E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 355 366 7.9E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 187 209 7.9E-31 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 PIRSF PIRSF000185 15 429 5.6E-172 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 SUPERFAMILY SSF51735 196 428 8.78E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 Gene3D G3DSA:3.40.50.10860 48 182 1.7E-51 T 29-03-2018 A616_RS13595 27f533beb07b984c027d89cf82f74cea 429 Gene3D G3DSA:3.40.50.720 196 429 1.7E-75 T 29-03-2018 A616_RS20880 811f94c22d08dea662951bfcf4bdb32b 177 SUPERFAMILY SSF140663 1 123 1.12E-31 T 29-03-2018 IPR023203 TTHA0068-like domain A616_RS20880 811f94c22d08dea662951bfcf4bdb32b 177 Gene3D G3DSA:1.10.3450.10 1 135 5.7E-39 T 29-03-2018 IPR023203 TTHA0068-like domain A616_RS20880 811f94c22d08dea662951bfcf4bdb32b 177 Pfam PF03745 Domain of unknown function (DUF309) 8 66 2.9E-23 T 29-03-2018 IPR005500 Protein of unknown function DUF309 A616_RS21865 977ae320115eeec625aff1f9023e9008 345 Pfam PF01032 FecCD transport family 31 340 7.8E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS21865 977ae320115eeec625aff1f9023e9008 345 SUPERFAMILY SSF81345 13 340 2.22E-77 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS21865 977ae320115eeec625aff1f9023e9008 345 Gene3D G3DSA:1.10.3470.10 14 345 7.3E-63 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS06105 481440434c6b7d344ffd1a188bd88f1c 223 Gene3D G3DSA:3.50.40.10 50 197 1.4E-20 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS06105 481440434c6b7d344ffd1a188bd88f1c 223 SMART SM00873 62 212 7.4E-9 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A616_RS06105 481440434c6b7d344ffd1a188bd88f1c 223 SUPERFAMILY SSF56037 54 217 3.66E-28 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A616_RS06105 481440434c6b7d344ffd1a188bd88f1c 223 Pfam PF03483 B3/4 domain 64 188 2.2E-16 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A616_RS08235 cc71d3c44dd9ce7518f25d78c1935128 218 SUPERFAMILY SSF46689 6 80 1.03E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS08235 cc71d3c44dd9ce7518f25d78c1935128 218 SUPERFAMILY SSF48498 110 214 6.67E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS08235 cc71d3c44dd9ce7518f25d78c1935128 218 Gene3D G3DSA:1.10.357.10 7 217 1.4E-22 T 29-03-2018 A616_RS08235 cc71d3c44dd9ce7518f25d78c1935128 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 1.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS08235 cc71d3c44dd9ce7518f25d78c1935128 218 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 119 214 3.7E-9 T 29-03-2018 A616_RS26780 fabf0003981bdd3b5308d6d568d45cdc 262 SMART SM00382 31 217 1.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS26780 fabf0003981bdd3b5308d6d568d45cdc 262 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS26780 fabf0003981bdd3b5308d6d568d45cdc 262 Gene3D G3DSA:3.40.50.300 4 252 2.3E-41 T 29-03-2018 A616_RS26780 fabf0003981bdd3b5308d6d568d45cdc 262 SUPERFAMILY SSF52540 7 234 1.77E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26780 fabf0003981bdd3b5308d6d568d45cdc 262 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 7 247 1.2E-113 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 A616_RS26780 fabf0003981bdd3b5308d6d568d45cdc 262 Pfam PF00005 ABC transporter 22 174 1.7E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 Pfam PF05199 GMC oxidoreductase 384 522 4.8E-24 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 93 116 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 PIRSF PIRSF000137 348 538 1.1E-29 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 PIRSF PIRSF000137 1 343 1.3E-69 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 SUPERFAMILY SSF51905 471 532 1.26E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 SUPERFAMILY SSF51905 11 313 1.26E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 Gene3D G3DSA:3.30.560.10 116 487 2.5E-54 T 29-03-2018 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 Gene3D G3DSA:4.10.450.10 46 115 3.3E-14 T 29-03-2018 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 SUPERFAMILY SSF54373 368 471 1.18E-10 T 29-03-2018 A616_RS07515 eb98ad197e10332bd86f2b90636cc9b8 538 Pfam PF00732 GMC oxidoreductase 13 320 1.0E-52 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 Gene3D G3DSA:3.30.450.20 197 334 5.1E-9 T 29-03-2018 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 Gene3D G3DSA:1.10.8.60 509 576 1.3E-16 T 29-03-2018 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 Pfam PF00158 Sigma-54 interaction domain 335 500 8.4E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 Pfam PF00989 PAS fold 212 264 5.4E-6 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 Gene3D G3DSA:1.10.10.10 594 668 1.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 SMART SM00091 211 277 3.8E-7 T 29-03-2018 IPR000014 PAS domain A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 Gene3D G3DSA:3.40.50.300 335 507 6.1E-23 T 29-03-2018 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 422 437 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 SUPERFAMILY SSF52540 334 574 1.7E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 SMART SM00382 355 500 4.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 SUPERFAMILY SSF55785 211 275 1.45E-9 T 29-03-2018 IPR000014 PAS domain A616_RS15460 ffcb1c2640ee365dec5fdc525e4a42f4 670 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 211 264 8.0E-7 T 29-03-2018 IPR000014 PAS domain A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 1.4E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 1.4E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 1.4E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 Pfam PF00850 Histone deacetylase domain 22 319 1.5E-80 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 SUPERFAMILY SSF52768 6 335 4.8E-109 T 29-03-2018 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 Gene3D G3DSA:3.40.800.20 2 349 4.7E-101 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 3.1E-31 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 3.1E-31 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 334 350 3.1E-31 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 3.1E-31 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 3.1E-31 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A616_RS22970 04346e61580738e36c04d6bffe4530ab 382 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 3.1E-31 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 A616_RS30955 1065742308ec7d1d622881dbb56d3762 506 Gene3D G3DSA:3.40.605.10 6 278 2.0E-97 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS30955 1065742308ec7d1d622881dbb56d3762 506 SUPERFAMILY SSF53720 14 498 7.33E-164 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS30955 1065742308ec7d1d622881dbb56d3762 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A616_RS30955 1065742308ec7d1d622881dbb56d3762 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS30955 1065742308ec7d1d622881dbb56d3762 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 4.8E-166 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS30955 1065742308ec7d1d622881dbb56d3762 506 Gene3D G3DSA:3.40.309.10 279 480 2.2E-65 T 29-03-2018 A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Pfam PF07676 WD40-like Beta Propeller Repeat 233 257 5.7E-5 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Pfam PF07676 WD40-like Beta Propeller Repeat 183 215 1.5E-6 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Pfam PF07676 WD40-like Beta Propeller Repeat 113 128 8.3E-5 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Pfam PF07676 WD40-like Beta Propeller Repeat 59 92 1.8E-10 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Gene3D G3DSA:3.40.50.1820 409 671 2.7E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Pfam PF00326 Prolyl oligopeptidase family 451 662 4.1E-54 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Gene3D G3DSA:2.130.10.150 17 207 1.2E-33 T 29-03-2018 A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 Gene3D G3DSA:2.130.10.150 208 398 9.6E-24 T 29-03-2018 A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 SUPERFAMILY SSF82171 17 396 3.66E-53 T 29-03-2018 A616_RS14805 fad6e8e4cfd1206bc814c67661f084a2 671 SUPERFAMILY SSF53474 405 662 1.58E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 Gene3D G3DSA:1.10.580.10 299 350 3.8E-10 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 SUPERFAMILY SSF48256 2 370 1.96E-132 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PRINTS PR00143 Citrate synthase signature 303 319 1.2E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PRINTS PR00143 Citrate synthase signature 122 135 1.2E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PRINTS PR00143 Citrate synthase signature 323 337 1.2E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PRINTS PR00143 Citrate synthase signature 193 221 1.2E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PRINTS PR00143 Citrate synthase signature 171 186 1.2E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PRINTS PR00143 Citrate synthase signature 246 266 1.2E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 PIRSF PIRSF001369 1 370 4.0E-148 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 370 6.8E-158 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 Pfam PF00285 Citrate synthase, C-terminal domain 6 353 1.1E-125 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 Gene3D G3DSA:1.10.580.10 11 259 4.9E-86 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A616_RS07990 7efcb7d8168895cfbc05c7b96cba8c7c 370 ProSitePatterns PS00480 Citrate synthase signature. 253 265 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A616_RS08055 8a34af12c88ca9a894f290bab5aca3cf 314 SUPERFAMILY SSF103481 199 294 1.7E-13 T 29-03-2018 A616_RS08055 8a34af12c88ca9a894f290bab5aca3cf 314 Pfam PF00892 EamA-like transporter family 12 144 1.1E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS08055 8a34af12c88ca9a894f290bab5aca3cf 314 Pfam PF00892 EamA-like transporter family 156 291 1.0E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS08055 8a34af12c88ca9a894f290bab5aca3cf 314 SUPERFAMILY SSF103481 43 148 7.98E-15 T 29-03-2018 A616_RS21545 675983d73c098b90fa2b2e184e387108 164 Pfam PF00583 Acetyltransferase (GNAT) family 14 139 9.5E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS21545 675983d73c098b90fa2b2e184e387108 164 Gene3D G3DSA:3.40.630.30 1 155 1.2E-27 T 29-03-2018 A616_RS21545 675983d73c098b90fa2b2e184e387108 164 SUPERFAMILY SSF55729 1 161 3.01E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS15515 ccbec1abe4a461932ae1572a013244a8 260 Gene3D G3DSA:1.10.12.10 219 258 3.1E-18 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS15515 ccbec1abe4a461932ae1572a013244a8 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS15515 ccbec1abe4a461932ae1572a013244a8 260 SUPERFAMILY SSF52096 3 259 2.49E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS15515 ccbec1abe4a461932ae1572a013244a8 260 Gene3D G3DSA:3.90.226.10 5 218 3.9E-61 T 29-03-2018 A616_RS15515 ccbec1abe4a461932ae1572a013244a8 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 259 8.2E-64 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 455 473 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 Gene3D G3DSA:3.20.20.60 262 580 2.7E-107 T 29-03-2018 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 Pfam PF00391 PEP-utilising enzyme, mobile domain 160 233 1.3E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 258 548 2.0E-127 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 192 203 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 PIRSF PIRSF000732 7 580 3.9E-231 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 Gene3D G3DSA:1.10.274.10 33 142 1.4E-37 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 455 470 3.6E-32 T 29-03-2018 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 508 520 3.6E-32 T 29-03-2018 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 472 487 3.6E-32 T 29-03-2018 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 301 320 3.6E-32 T 29-03-2018 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 SUPERFAMILY SSF51621 258 554 7.07E-116 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 SUPERFAMILY SSF47831 32 151 4.84E-36 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 Gene3D G3DSA:3.50.30.10 143 261 2.8E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 SUPERFAMILY SSF52009 133 253 9.81E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 Pfam PF05524 PEP-utilising enzyme, N-terminal 13 134 7.6E-34 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A616_RS30810 f6736d87ff7ea0564514c811c2604d1a 580 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 12 574 3.2E-236 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A616_RS13505 eb5dbb61324ed5182d24b18f70186648 544 Pfam PF05140 ResB-like family 66 430 4.2E-71 T 29-03-2018 IPR007816 ResB-like domain A616_RS13505 eb5dbb61324ed5182d24b18f70186648 544 Pfam PF05140 ResB-like family 447 523 2.6E-16 T 29-03-2018 IPR007816 ResB-like domain A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 SUPERFAMILY SSF55604 407 478 4.18E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 419 436 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 476 1.6E-169 T 29-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 Pfam PF02378 Phosphotransferase system, EIIC 10 320 1.0E-72 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 Pfam PF00367 phosphotransferase system, EIIB 409 441 5.5E-15 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 378 466 6.3E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A616_RS00360 4b47ad349bfa55326aaeba392bc89b9c 479 Gene3D G3DSA:3.30.1360.60 404 479 4.8E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A616_RS30825 93a368012575237298590729cf256081 701 SUPERFAMILY SSF46785 1 46 5.61E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30825 93a368012575237298590729cf256081 701 Gene3D G3DSA:1.10.1790.10 307 413 2.1E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS30825 93a368012575237298590729cf256081 701 Gene3D G3DSA:1.10.1790.10 162 303 1.4E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS30825 93a368012575237298590729cf256081 701 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 558 684 1.1E-15 T 29-03-2018 IPR002178 PTS EIIA type-2 domain A616_RS30825 93a368012575237298590729cf256081 701 Gene3D G3DSA:3.40.50.2300 417 505 1.6E-18 T 29-03-2018 A616_RS30825 93a368012575237298590729cf256081 701 SUPERFAMILY SSF63520 313 412 2.88E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS30825 93a368012575237298590729cf256081 701 SUPERFAMILY SSF63520 199 302 1.57E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS30825 93a368012575237298590729cf256081 701 Pfam PF08279 HTH domain 6 60 1.5E-9 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS30825 93a368012575237298590729cf256081 701 SUPERFAMILY SSF52794 419 502 5.18E-11 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A616_RS30825 93a368012575237298590729cf256081 701 Gene3D G3DSA:1.10.10.10 1 67 1.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30825 93a368012575237298590729cf256081 701 Gene3D G3DSA:1.10.10.10 83 154 3.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30825 93a368012575237298590729cf256081 701 SUPERFAMILY SSF55804 557 683 2.88E-18 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A616_RS30825 93a368012575237298590729cf256081 701 Pfam PF05043 Mga helix-turn-helix domain 81 164 2.8E-5 T 29-03-2018 IPR007737 Mga helix-turn-helix domain A616_RS30825 93a368012575237298590729cf256081 701 Gene3D G3DSA:3.40.930.10 547 687 3.5E-21 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A616_RS30825 93a368012575237298590729cf256081 701 Pfam PF00874 PRD domain 322 409 1.6E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS30825 93a368012575237298590729cf256081 701 Pfam PF00874 PRD domain 213 298 2.3E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 SUPERFAMILY SSF54211 1 181 2.02E-47 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 SUPERFAMILY SSF55666 154 239 2.23E-23 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 48.286 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 Gene3D G3DSA:3.30.230.70 1 240 1.6E-60 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.7E-116 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 Pfam PF03725 3' exoribonuclease family, domain 2 159 222 3.4E-13 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS10275 d3cfafe5b22ede69c59945fc03a7212f 253 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 2.0E-25 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 SUPERFAMILY SSF52242 543 705 2.31E-38 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 Gene3D G3DSA:3.20.20.240 38 545 4.0E-160 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 Pfam PF01642 Methylmalonyl-CoA mutase 39 541 2.8E-166 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 SUPERFAMILY SSF51703 5 540 6.02E-150 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 379 404 - T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 40 540 3.7E-102 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 Gene3D G3DSA:3.40.50.280 568 707 9.6E-25 T 29-03-2018 A616_RS14840 33a224031cf69aae4cb9032cc14ff84f 707 Gene3D G3DSA:1.10.196.20 8 37 4.6E-6 T 29-03-2018 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 A616_RS25525 09ad8238a5d63a22f9d9697cae03d312 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 273 7.9E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25525 09ad8238a5d63a22f9d9697cae03d312 285 Gene3D G3DSA:1.10.3720.10 9 272 1.7E-43 T 29-03-2018 A616_RS25525 09ad8238a5d63a22f9d9697cae03d312 285 SUPERFAMILY SSF161098 16 284 7.29E-75 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25220 46164f0ef9be0d5268da9ee5e4c85a47 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 284 3.2E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS25220 46164f0ef9be0d5268da9ee5e4c85a47 300 Gene3D G3DSA:1.10.3470.10 1 287 2.0E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS11710 0d68d1203637b3b297289b13b79713aa 244 PIRSF PIRSF018637 4 239 4.5E-78 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 A616_RS11710 0d68d1203637b3b297289b13b79713aa 244 Gene3D G3DSA:3.40.50.150 1 165 2.5E-18 T 29-03-2018 A616_RS11710 0d68d1203637b3b297289b13b79713aa 244 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 232 3.1E-64 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 A616_RS11710 0d68d1203637b3b297289b13b79713aa 244 SUPERFAMILY SSF53335 9 138 2.2E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS21920 ad1d899475f99becbb87f506845e337c 396 Gene3D G3DSA:1.20.1250.20 195 386 4.0E-8 T 29-03-2018 A616_RS21920 ad1d899475f99becbb87f506845e337c 396 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 10 386 2.1E-76 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A616_RS21920 ad1d899475f99becbb87f506845e337c 396 Gene3D G3DSA:1.20.1250.20 1 194 2.9E-33 T 29-03-2018 A616_RS21920 ad1d899475f99becbb87f506845e337c 396 SUPERFAMILY SSF103473 4 384 6.93E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS21920 ad1d899475f99becbb87f506845e337c 396 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 5.3E-9 T 29-03-2018 A616_RS21920 ad1d899475f99becbb87f506845e337c 396 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 5.3E-9 T 29-03-2018 A616_RS21920 ad1d899475f99becbb87f506845e337c 396 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 5.3E-9 T 29-03-2018 A616_RS21920 ad1d899475f99becbb87f506845e337c 396 Pfam PF07690 Major Facilitator Superfamily 22 355 4.2E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS15330 9454e74ed7e189823cf29775cc201043 258 Gene3D G3DSA:1.10.12.10 216 258 3.1E-19 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS15330 9454e74ed7e189823cf29775cc201043 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS15330 9454e74ed7e189823cf29775cc201043 258 SUPERFAMILY SSF52096 2 257 1.42E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS15330 9454e74ed7e189823cf29775cc201043 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 257 3.0E-66 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS15330 9454e74ed7e189823cf29775cc201043 258 Gene3D G3DSA:3.90.226.10 3 215 1.1E-68 T 29-03-2018 A616_RS28935 872618337e058f2aa15ce15a0c92b73a 328 SUPERFAMILY SSF52540 3 237 3.34E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28935 872618337e058f2aa15ce15a0c92b73a 328 Gene3D G3DSA:3.40.50.300 1 306 7.1E-63 T 29-03-2018 A616_RS28935 872618337e058f2aa15ce15a0c92b73a 328 SMART SM00382 37 229 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28935 872618337e058f2aa15ce15a0c92b73a 328 Pfam PF00005 ABC transporter 29 172 1.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 Gene3D G3DSA:3.40.50.300 310 492 4.0E-39 T 29-03-2018 A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 SUPERFAMILY SSF52540 3 197 1.12E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 SMART SM00382 334 491 0.027 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 SMART SM00382 30 190 0.0013 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 ProSitePatterns PS00211 ABC transporters family signature. 423 437 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 Gene3D G3DSA:3.40.50.300 1 309 1.4E-39 T 29-03-2018 A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 Pfam PF00005 ABC transporter 22 146 1.3E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 Pfam PF00005 ABC transporter 327 451 1.9E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15445 26895d95615984bce59089d8b5bd3fb4 492 SUPERFAMILY SSF52540 298 492 1.33E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 SUPERFAMILY SSF158472 314 363 2.62E-6 T 29-03-2018 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 Gene3D G3DSA:3.30.450.20 179 291 2.4E-16 T 29-03-2018 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 Pfam PF06580 Histidine kinase 377 455 2.8E-25 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 SMART SM00304 312 364 0.0014 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 555 5.3E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 577 5.3E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 5.3E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 SMART SM00387 472 580 1.1E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 SUPERFAMILY SSF55874 432 577 1.83E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 578 4.6E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 Gene3D G3DSA:3.30.450.20 87 178 1.9E-9 T 29-03-2018 A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 Gene3D G3DSA:3.30.565.10 343 578 2.7E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03935 0c170a927a6e033dd065062b45eb2010 587 Pfam PF02743 Cache domain 43 274 3.0E-30 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS14445 f855cd9c5f3811870f2d24d224118bbf 370 Pfam PF00589 Phage integrase family 206 358 1.2E-26 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS14445 f855cd9c5f3811870f2d24d224118bbf 370 Gene3D G3DSA:1.10.150.130 14 135 2.5E-17 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS14445 f855cd9c5f3811870f2d24d224118bbf 370 SUPERFAMILY SSF56349 205 367 6.47E-36 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS14445 f855cd9c5f3811870f2d24d224118bbf 370 Gene3D G3DSA:1.10.443.10 170 367 3.6E-33 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 SUPERFAMILY SSF50156 109 228 3.64E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 Gene3D G3DSA:3.30.750.44 29 145 1.8E-11 T 29-03-2018 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 SUPERFAMILY SSF52096 231 403 8.62E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 SUPERFAMILY SSF52096 79 156 8.62E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 Gene3D G3DSA:2.30.42.10 146 211 9.2E-20 T 29-03-2018 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 Pfam PF03572 Peptidase family S41 238 400 9.8E-42 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 Gene3D G3DSA:3.90.226.10 212 445 2.2E-49 T 29-03-2018 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 Pfam PF13180 PDZ domain 140 218 2.3E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 SMART SM00245 211 401 4.6E-50 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 105 405 3.1E-76 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A616_RS11725 4837f1c4f3d7a6c8efb83d4cb14cfbca 498 SMART SM00228 138 209 6.0E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 Gene3D G3DSA:1.10.530.10 1 152 2.3E-34 T 29-03-2018 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 PRINTS PR01002 Flagellar protein FlgJ signature 66 87 3.9E-15 T 29-03-2018 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 PRINTS PR01002 Flagellar protein FlgJ signature 129 147 3.9E-15 T 29-03-2018 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 PRINTS PR01002 Flagellar protein FlgJ signature 25 43 3.9E-15 T 29-03-2018 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 PRINTS PR01002 Flagellar protein FlgJ signature 109 128 3.9E-15 T 29-03-2018 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 13 148 4.8E-21 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A616_RS21620 eda7d4613c47ec2c9bbe68b06b496f2b 212 SMART SM00047 4 152 2.3E-29 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A616_RS07425 56663fb830d7eee4338fa2789881ab43 247 SUPERFAMILY SSF55383 29 82 1.44E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS07425 56663fb830d7eee4338fa2789881ab43 247 Gene3D G3DSA:1.20.5.1230 120 236 5.3E-4 T 29-03-2018 A616_RS07425 56663fb830d7eee4338fa2789881ab43 247 Gene3D G3DSA:3.30.457.10 15 78 1.0E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS07425 56663fb830d7eee4338fa2789881ab43 247 Pfam PF07833 Copper amine oxidase N-terminal domain 27 88 3.6E-9 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS07425 56663fb830d7eee4338fa2789881ab43 247 Gene3D G3DSA:1.20.5.50 94 119 1.2E-5 T 29-03-2018 A616_RS14010 e5b2c003056d970e95f36047368a3276 957 Gene3D G3DSA:2.20.210.10 545 957 0.004 T 29-03-2018 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 Gene3D G3DSA:3.30.70.1560 145 209 3.9E-24 T 29-03-2018 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 SMART SM00363 2 64 3.5E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 Gene3D G3DSA:3.10.290.10 1 58 7.0E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 Pfam PF00849 RNA pseudouridylate synthase 63 197 1.7E-25 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 SUPERFAMILY SSF55120 49 236 3.2E-49 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 Pfam PF01479 S4 domain 2 44 2.0E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 SUPERFAMILY SSF55174 2 68 1.16E-13 T 29-03-2018 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 Gene3D G3DSA:3.30.70.580 59 144 4.9E-22 T 29-03-2018 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A616_RS13495 c709c789c9c545b5b8719847eb469771 246 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 227 2.5E-54 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 13 414 1.7E-140 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 Pfam PF01546 Peptidase family M20/M25/M40 83 413 3.3E-26 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 Gene3D G3DSA:3.40.630.10 255 419 2.2E-16 T 29-03-2018 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 SUPERFAMILY SSF55031 219 335 1.0E-25 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 Gene3D G3DSA:3.40.630.10 5 254 4.4E-47 T 29-03-2018 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 Pfam PF07687 Peptidase dimerisation domain 218 320 6.6E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 PIRSF PIRSF001235 7 419 1.2E-136 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 SUPERFAMILY SSF53187 343 415 8.47E-85 T 29-03-2018 A616_RS14255 9075c09df84037cb0d9c02f090da1157 419 SUPERFAMILY SSF53187 7 229 8.47E-85 T 29-03-2018 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 SUPERFAMILY SSF53633 2 246 3.67E-67 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 Gene3D G3DSA:3.30.70.260 240 335 7.8E-16 T 29-03-2018 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 Gene3D G3DSA:3.40.1160.10 1 239 8.9E-64 T 29-03-2018 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 PIRSF PIRSF000726 1 66 1.7E-6 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 PIRSF PIRSF000726 59 408 1.2E-91 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 403 9.7E-128 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 SUPERFAMILY SSF55021 337 404 8.88E-16 T 29-03-2018 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 Pfam PF00696 Amino acid kinase family 2 235 2.4E-47 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 Pfam PF13840 ACT domain 339 399 6.8E-21 T 29-03-2018 IPR027795 GATS-like ACT domain A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 61 402 1.3E-95 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 SUPERFAMILY SSF55021 261 347 9.92E-14 T 29-03-2018 A616_RS19730 0c8af5594e2c0b2ec4dc36f5f06213c3 408 Gene3D G3DSA:3.30.70.260 336 403 3.4E-13 T 29-03-2018 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 SUPERFAMILY SSF102114 124 365 5.89E-54 T 29-03-2018 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 422 1.2E-142 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 Pfam PF04055 Radical SAM superfamily 150 318 1.3E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 Gene3D G3DSA:3.80.30.20 141 375 9.3E-50 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 SMART SM00729 144 361 6.6E-55 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 5.6E-144 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 148 168 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A616_RS11490 6808ce5b91764328c2e0f323f771eb3f 452 Pfam PF00919 Uncharacterized protein family UPF0004 4 99 1.5E-26 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A616_RS30595 ba05da79ea55b6fcc55c36834bb83121 469 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A616_RS30595 ba05da79ea55b6fcc55c36834bb83121 469 Pfam PF00324 Amino acid permease 19 450 2.3E-119 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A616_RS30595 ba05da79ea55b6fcc55c36834bb83121 469 PIRSF PIRSF006060 2 464 4.3E-76 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS21495 ed9579d32428a054b049c23b8f9cae54 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 2.3E-148 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS21495 ed9579d32428a054b049c23b8f9cae54 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS21495 ed9579d32428a054b049c23b8f9cae54 387 Gene3D G3DSA:3.90.1150.10 247 383 4.0E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS21495 ed9579d32428a054b049c23b8f9cae54 387 PIRSF PIRSF001434 1 379 1.2E-139 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS21495 ed9579d32428a054b049c23b8f9cae54 387 SUPERFAMILY SSF53383 5 377 7.4E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS21495 ed9579d32428a054b049c23b8f9cae54 387 Gene3D G3DSA:3.40.640.10 1 245 4.7E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS15845 e64eaa35f556b31ef9b9ce2295f408ab 263 Pfam PF01925 Sulfite exporter TauE/SafE 9 252 5.7E-39 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A616_RS16315 ba2f3f2276b623b418407464d6fc0d7f 368 Pfam PF05816 Toxic anion resistance protein (TelA) 41 348 4.1E-49 T 29-03-2018 IPR008863 Toxic anion resistance A616_RS22835 691850c785377d00625c6f80aff0b2fb 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 1.6E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS22835 691850c785377d00625c6f80aff0b2fb 306 SUPERFAMILY SSF161098 88 287 1.11E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS22835 691850c785377d00625c6f80aff0b2fb 306 Gene3D G3DSA:1.10.3720.10 1 294 1.2E-44 T 29-03-2018 A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 SUPERFAMILY SSF56219 950 1076 1.16E-33 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 SUPERFAMILY SSF56219 1107 1285 1.16E-33 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 SMART SM00635 1736 1823 2.0E-5 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Gene3D G3DSA:2.60.40.1260 37 212 3.1E-14 T 29-03-2018 IPR001322 Lamin Tail Domain A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Gene3D G3DSA:2.40.50.200 401 512 1.3E-12 T 29-03-2018 A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Gene3D G3DSA:2.60.40.1080 1733 1825 1.4E-13 T 29-03-2018 A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 620 684 1.2E-18 T 29-03-2018 A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Gene3D G3DSA:3.60.10.10 962 1267 5.9E-34 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Pfam PF00932 Lamin Tail Domain 37 164 7.0E-13 T 29-03-2018 IPR001322 Lamin Tail Domain A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Gene3D G3DSA:2.60.40.10 618 685 8.3E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS07610 8a7c8663a1f6a1dd4b4a736abe1a2292 1825 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 965 1235 1.3E-6 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 PIRSF PIRSF000106 45 412 1.2E-87 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 SUPERFAMILY SSF53223 7 159 5.83E-57 T 29-03-2018 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 SMART SM01274 16 149 2.8E-85 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 Gene3D G3DSA:3.40.50.720 159 411 1.3E-86 T 29-03-2018 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 ProSitePatterns PS00331 Malic enzymes signature. 157 173 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 Pfam PF03949 Malic enzyme, NAD binding domain 163 384 1.8E-25 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 PRINTS PR00072 Malic enzyme signature 78 100 6.0E-7 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 PRINTS PR00072 Malic enzyme signature 157 173 6.0E-7 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 PRINTS PR00072 Malic enzyme signature 277 293 6.0E-7 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 SMART SM00919 161 385 4.6E-135 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 Pfam PF00390 Malic enzyme, N-terminal domain 16 149 4.3E-30 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 Gene3D G3DSA:3.40.50.10380 4 158 5.3E-42 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A616_RS07925 aee73f726f24fb5dd49757b8371a0f6c 414 SUPERFAMILY SSF51735 161 405 2.63E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 SUPERFAMILY SSF48029 9 103 7.32E-22 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 Pfam PF01706 FliG C-terminal domain 221 327 1.1E-42 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 SUPERFAMILY SSF48029 117 328 1.12E-69 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 8 24 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 117 140 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PRINTS PR00954 Flagellar motor switch protein FliG signature 37 63 1.1E-76 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 Gene3D G3DSA:1.10.220.30 198 337 1.5E-36 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 Gene3D G3DSA:1.10.220.30 6 85 1.0E-14 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 Gene3D G3DSA:1.10.220.30 86 196 9.2E-22 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 Pfam PF14842 FliG N-terminal domain 7 110 6.9E-37 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 PIRSF PIRSF003161 3 337 4.2E-122 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 337 1.1E-146 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A616_RS20035 9e7d2cb8dfbfa09c6ebb129aca5e177b 337 Pfam PF14841 FliG middle domain 118 192 4.6E-32 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain A616_RS19570 7fbf433a2d5f8c88780125213dd689a1 186 Gene3D G3DSA:3.40.50.150 3 186 4.3E-26 T 29-03-2018 A616_RS19570 7fbf433a2d5f8c88780125213dd689a1 186 Pfam PF06962 Putative rRNA methylase 47 182 8.3E-51 T 29-03-2018 IPR010719 Putative rRNA methylase A616_RS19570 7fbf433a2d5f8c88780125213dd689a1 186 SUPERFAMILY SSF53335 17 160 8.07E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS19025 e677ba0ef3aae52fbbb1f39b3f3fe973 361 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 16 354 2.9E-140 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A616_RS19025 e677ba0ef3aae52fbbb1f39b3f3fe973 361 Pfam PF00676 Dehydrogenase E1 component 43 333 5.1E-92 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A616_RS19025 e677ba0ef3aae52fbbb1f39b3f3fe973 361 SUPERFAMILY SSF52518 12 357 6.44E-99 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS19025 e677ba0ef3aae52fbbb1f39b3f3fe973 361 Gene3D G3DSA:3.40.50.970 2 355 7.6E-89 T 29-03-2018 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 PIRSF PIRSF001365 1 288 1.6E-89 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 SMART SM01130 3 287 4.4E-128 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 Gene3D G3DSA:3.20.20.70 2 288 4.3E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 285 2.1E-101 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 288 60.669 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 SUPERFAMILY SSF51569 4 287 1.36E-97 T 29-03-2018 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 Pfam PF00701 Dihydrodipicolinate synthetase family 4 287 1.5E-98 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 4.0E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 4.0E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 4.0E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS19725 b13c115cbbc3a472c15aeafba3fbc78b 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 4.0E-32 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A616_RS30555 d0c8968f7c3e2b7d3674979c011887f8 205 Gene3D G3DSA:3.30.565.40 2 111 6.2E-15 T 29-03-2018 A616_RS30555 d0c8968f7c3e2b7d3674979c011887f8 205 Gene3D G3DSA:3.90.640.20 113 198 1.9E-20 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 A616_RS30555 d0c8968f7c3e2b7d3674979c011887f8 205 Pfam PF13739 Domain of unknown function (DUF4163) 20 97 7.1E-9 T 29-03-2018 IPR025303 Deacetylase PdaC A616_RS30555 d0c8968f7c3e2b7d3674979c011887f8 205 Pfam PF11738 Protein of unknown function (DUF3298) 116 185 2.9E-16 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 Gene3D G3DSA:1.10.357.10 57 197 8.5E-17 T 29-03-2018 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.9E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 SUPERFAMILY SSF46689 3 80 2.21E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 184 1.2E-8 T 29-03-2018 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 Gene3D G3DSA:1.10.10.60 1 56 5.2E-18 T 29-03-2018 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS26505 2c932a2cb7d79001b4aadfdc3f29cc3e 208 SUPERFAMILY SSF48498 87 186 2.61E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 Gene3D G3DSA:1.10.10.10 12 75 1.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 SUPERFAMILY SSF53067 82 394 1.1E-50 T 29-03-2018 A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 SUPERFAMILY SSF46785 9 74 9.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 Gene3D G3DSA:3.30.420.40 200 399 6.7E-49 T 29-03-2018 A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 Gene3D G3DSA:3.30.420.40 76 199 4.4E-17 T 29-03-2018 A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 Pfam PF00480 ROK family 84 372 9.6E-56 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 ProSitePatterns PS01125 ROK family signature. 215 242 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS09905 62e228048a8ef224d3530d11c1ea84bd 401 Pfam PF13412 Winged helix-turn-helix DNA-binding 15 57 1.3E-8 T 29-03-2018 A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 Gene3D G3DSA:2.60.120.10 72 185 1.5E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 Pfam PF01381 Helix-turn-helix 12 64 1.4E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 SUPERFAMILY SSF51182 59 182 2.88E-28 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 Pfam PF07883 Cupin domain 111 178 3.2E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 SMART SM00530 11 66 9.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 SUPERFAMILY SSF47413 3 72 2.04E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS15900 32088151cd3805dc2d84726a0cef90a7 185 Gene3D G3DSA:1.10.260.40 1 71 7.2E-17 T 29-03-2018 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 Gene3D G3DSA:2.130.10.30 55 405 6.5E-37 T 29-03-2018 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 Gene3D G3DSA:2.130.10.30 406 703 4.3E-7 T 29-03-2018 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 344 357 3.4E-5 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 471 487 3.4E-5 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 312 328 3.4E-5 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 363 379 3.4E-5 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 310 357 2.8E-8 T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 SUPERFAMILY SSF50985 102 211 3.66E-31 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 SUPERFAMILY SSF50985 292 453 3.66E-31 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A616_RS17730 dc1498ccab5b7d8e585b8d32d08183b3 704 SUPERFAMILY SSF50985 510 546 3.66E-31 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A616_RS08470 76e570ac8f581cdb9ad405bc254e716c 135 SUPERFAMILY SSF54593 5 131 1.88E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS08470 76e570ac8f581cdb9ad405bc254e716c 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 126 3.6E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS08470 76e570ac8f581cdb9ad405bc254e716c 135 Gene3D G3DSA:3.10.180.10 2 135 3.5E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS08040 5a513425768da1347951836a96ff9cfd 219 Gene3D G3DSA:2.40.50.100 104 190 0.0035 T 29-03-2018 A616_RS08040 5a513425768da1347951836a96ff9cfd 219 Gene3D G3DSA:2.40.50.100 44 103 4.2E-12 T 29-03-2018 A616_RS08040 5a513425768da1347951836a96ff9cfd 219 Pfam PF13437 HlyD family secretion protein 89 199 8.8E-14 T 29-03-2018 A616_RS08040 5a513425768da1347951836a96ff9cfd 219 SUPERFAMILY SSF51230 37 117 1.37E-7 T 29-03-2018 IPR011053 Single hybrid motif A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 Pfam PF13614 AAA domain 2 178 3.4E-72 T 29-03-2018 IPR025669 AAA domain A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 Gene3D G3DSA:3.40.50.300 2 252 2.9E-64 T 29-03-2018 A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 PRINTS PR00091 Nitrogenase component II signature 31 46 7.2E-5 T 29-03-2018 A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 PRINTS PR00091 Nitrogenase component II signature 9 22 7.2E-5 T 29-03-2018 A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 SUPERFAMILY SSF52540 2 251 3.67E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 PIRSF PIRSF009320 2 62 1.5E-16 T 29-03-2018 A616_RS32255 9407b4184e9f1d07176dc9988b5d7ff7 252 PIRSF PIRSF009320 90 251 5.4E-9 T 29-03-2018 A616_RS09630 0dff96f717dad58b295c3832590818f1 275 Gene3D G3DSA:3.40.50.10780 1 210 5.0E-84 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal A616_RS09630 0dff96f717dad58b295c3832590818f1 275 SUPERFAMILY SSF63992 1 273 7.85E-89 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A616_RS09630 0dff96f717dad58b295c3832590818f1 275 Gene3D G3DSA:3.30.1360.130 211 270 1.9E-15 T 29-03-2018 A616_RS09630 0dff96f717dad58b295c3832590818f1 275 PIRSF PIRSF015853 1 274 4.5E-91 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A616_RS09630 0dff96f717dad58b295c3832590818f1 275 Pfam PF04951 D-aminopeptidase 1 263 6.1E-93 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 677 40.58 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 SUPERFAMILY SSF56784 298 561 8.25E-41 T 29-03-2018 IPR023214 HAD-like domain A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 Gene3D G3DSA:3.40.1110.10 313 440 4.2E-21 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 Pfam PF00122 E1-E2 ATPase 103 279 2.5E-36 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 SUPERFAMILY SSF81653 108 204 7.72E-23 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 Gene3D G3DSA:2.70.150.10 16 205 1.5E-27 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 7 673 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 Gene3D G3DSA:3.40.50.1000 441 569 1.2E-34 T 29-03-2018 IPR023214 HAD-like domain A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 304 310 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 SUPERFAMILY SSF81665 31 103 5.89E-9 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 SUPERFAMILY SSF81665 205 296 5.89E-9 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 SUPERFAMILY SSF81665 616 658 5.89E-9 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 Pfam PF00702 haloacid dehalogenase-like hydrolase 298 527 2.0E-35 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 6.2E-26 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 438 449 6.2E-26 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 470 6.2E-26 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 151 165 6.2E-26 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 548 6.2E-26 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 532 6.2E-26 T 29-03-2018 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 371 602 7.4E-47 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02280 16a6e6ed44bf65c57ae575679bdcb27d 679 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 336 1.2E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 Gene3D G3DSA:3.40.50.2300 1 124 2.3E-28 T 29-03-2018 A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 SMART SM00448 2 113 8.5E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 Pfam PF00072 Response regulator receiver domain 4 113 4.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 Gene3D G3DSA:1.10.10.10 125 232 4.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 SMART SM00862 148 225 1.2E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 SUPERFAMILY SSF46894 122 226 5.67E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 SUPERFAMILY SSF52172 3 119 1.42E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS08420 556cbe5cfeb68cb99c168e723669ed66 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.9E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08805 fccaf071626779ba113b9bbaa93a0726 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 2.2E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS08805 fccaf071626779ba113b9bbaa93a0726 313 Gene3D G3DSA:1.10.3720.10 2 301 2.4E-44 T 29-03-2018 A616_RS08805 fccaf071626779ba113b9bbaa93a0726 313 SUPERFAMILY SSF161098 89 298 2.88E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 5.9E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 SUPERFAMILY SSF46894 124 226 8.5E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 SUPERFAMILY SSF52172 2 124 3.56E-41 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 SMART SM00448 1 111 2.8E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 Gene3D G3DSA:3.40.50.2300 1 123 3.4E-37 T 29-03-2018 A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 Gene3D G3DSA:1.10.10.10 124 227 4.6E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 Pfam PF00072 Response regulator receiver domain 3 111 2.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31075 42e7b3a0c7ebdebce3770e8fdb0c78fb 227 SMART SM00862 149 225 4.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 Gene3D G3DSA:3.40.50.720 47 271 2.4E-58 T 29-03-2018 A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 Gene3D G3DSA:3.40.50.720 1 46 1.1E-12 T 29-03-2018 A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 SUPERFAMILY SSF51735 6 269 1.84E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 1.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 268 1.1E-52 T 29-03-2018 A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15535 138cfb7f5d16711dc6285e3e81123ca7 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 Gene3D G3DSA:3.30.230.30 4 133 7.9E-46 T 29-03-2018 IPR001498 Impact, N-terminal A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 SUPERFAMILY SSF54980 135 200 5.55E-13 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 SUPERFAMILY SSF54211 2 130 6.83E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 Pfam PF09186 Domain of unknown function (DUF1949) 140 195 2.4E-15 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 Gene3D G3DSA:3.30.70.240 135 198 2.4E-19 T 29-03-2018 A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 Pfam PF01205 Uncharacterized protein family UPF0029 20 121 1.4E-31 T 29-03-2018 IPR001498 Impact, N-terminal A616_RS29755 c54e2b966c8f488baf55fd1ee206557f 219 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 202 5.7E-64 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 SUPERFAMILY SSF51735 3 293 7.61E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 Pfam PF12697 Alpha/beta hydrolase family 382 617 2.7E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 Gene3D G3DSA:3.40.50.720 2 357 6.5E-34 T 29-03-2018 A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 Gene3D G3DSA:3.40.50.1820 362 622 8.6E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 Pfam PF07993 Male sterility protein 6 238 1.4E-25 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 SUPERFAMILY SSF53474 372 621 5.94E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 PRINTS PR00111 Alpha/beta hydrolase fold signature 403 418 3.8E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 PRINTS PR00111 Alpha/beta hydrolase fold signature 460 473 3.8E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 PRINTS PR00111 Alpha/beta hydrolase fold signature 570 584 3.8E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28390 7df6165f475a4b22dd4fe99789740b81 627 PRINTS PR00111 Alpha/beta hydrolase fold signature 446 459 3.8E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00385 P450 superfamily signature 272 283 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00385 P450 superfamily signature 339 348 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00385 P450 superfamily signature 236 253 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00385 P450 superfamily signature 348 359 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 Gene3D G3DSA:1.10.630.10 6 381 3.0E-70 T 29-03-2018 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 289 316 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 130 146 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 317 332 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 339 348 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 272 283 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 348 359 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 84 95 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 147 162 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 PRINTS PR00359 B-class P450 signature 190 212 1.2E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 Pfam PF00067 Cytochrome P450 37 369 7.5E-38 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS22010 ce4b670a0045930e90ee708d193708c8 388 SUPERFAMILY SSF48264 19 374 2.62E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Pfam PF04898 Glutamate synthase central domain 465 748 3.3E-112 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Gene3D G3DSA:2.160.20.60 1231 1507 2.6E-114 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Pfam PF01645 Conserved region in glutamate synthase 809 1174 1.1E-158 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Gene3D G3DSA:3.20.20.70 792 1229 1.1E-158 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Pfam PF01493 GXGXG motif 1257 1444 5.1E-86 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Gene3D G3DSA:3.60.20.10 22 445 2.2E-163 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 SUPERFAMILY SSF56235 22 440 4.5E-155 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 SUPERFAMILY SSF51395 456 1212 4.89E-260 T 29-03-2018 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Pfam PF00310 Glutamine amidotransferases class-II 22 437 3.0E-188 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 SUPERFAMILY SSF69336 1225 1493 3.4E-96 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS15095 6ca68ed58ac0c4ebcfe3fe2c371a32bc 1537 Gene3D G3DSA:3.20.20.70 446 791 4.4E-95 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 SMART SM00345 20 79 9.9E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 Gene3D G3DSA:3.40.640.10 163 370 1.9E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 SUPERFAMILY SSF46785 9 86 5.07E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 Pfam PF00155 Aminotransferase class I and II 124 470 2.3E-29 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 Gene3D G3DSA:3.90.1150.10 371 482 1.5E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 3.0E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 SUPERFAMILY SSF53383 105 479 1.92E-91 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 Gene3D G3DSA:1.10.10.10 3 81 2.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 4.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS27030 6c4612ef90035275567e04260e68b0fe 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 4.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS30855 9ffe2dcda7bf0c1f69a5eaec1f0d7725 542 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 542 45.717 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A616_RS30855 9ffe2dcda7bf0c1f69a5eaec1f0d7725 542 Pfam PF01268 Formate--tetrahydrofolate ligase 1 541 1.4E-250 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A616_RS30855 9ffe2dcda7bf0c1f69a5eaec1f0d7725 542 SUPERFAMILY SSF52540 1 540 6.55E-230 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30855 9ffe2dcda7bf0c1f69a5eaec1f0d7725 542 Gene3D G3DSA:3.40.50.300 221 428 2.2E-76 T 29-03-2018 A616_RS30855 9ffe2dcda7bf0c1f69a5eaec1f0d7725 542 Gene3D G3DSA:3.40.50.300 1 220 5.4E-86 T 29-03-2018 A616_RS30855 9ffe2dcda7bf0c1f69a5eaec1f0d7725 542 Gene3D G3DSA:3.10.410.10 430 518 4.8E-34 T 29-03-2018 A616_RS23715 b259482b6da5d328c93821a7000bd1b0 489 Pfam PF13520 Amino acid permease 27 448 6.1E-47 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS23715 b259482b6da5d328c93821a7000bd1b0 489 PIRSF PIRSF006060 2 487 6.1E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS03845 e9d6234c7bdfe5c082f812ca17d0d131 324 SUPERFAMILY SSF51430 1 313 1.24E-100 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS03845 e9d6234c7bdfe5c082f812ca17d0d131 324 PRINTS PR00069 Aldo-keto reductase signature 39 63 6.0E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS03845 e9d6234c7bdfe5c082f812ca17d0d131 324 PRINTS PR00069 Aldo-keto reductase signature 134 151 6.0E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS03845 e9d6234c7bdfe5c082f812ca17d0d131 324 PRINTS PR00069 Aldo-keto reductase signature 103 121 6.0E-9 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS03845 e9d6234c7bdfe5c082f812ca17d0d131 324 Pfam PF00248 Aldo/keto reductase family 16 309 1.1E-78 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS03845 e9d6234c7bdfe5c082f812ca17d0d131 324 Gene3D G3DSA:3.20.20.100 3 313 5.5E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 SUPERFAMILY SSF52374 163 374 6.22E-87 T 29-03-2018 A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 Gene3D G3DSA:3.10.400.10 20 171 9.5E-55 T 29-03-2018 A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 25 373 1.4E-133 T 29-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 Gene3D G3DSA:3.40.50.620 172 373 2.8E-93 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 Pfam PF14306 PUA-like domain 25 155 4.0E-43 T 29-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 SUPERFAMILY SSF88697 25 157 6.16E-42 T 29-03-2018 IPR015947 PUA-like domain A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 Pfam PF01747 ATP-sulfurylase 163 373 1.2E-93 T 29-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A616_RS09470 375634ebc8cacb9f3ae1d201087cf562 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 20 377 48.647 T 29-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A616_RS26020 50146722385ca0782fc37cd5703eef23 248 Pfam PF13545 Crp-like helix-turn-helix domain 151 229 2.6E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS26020 50146722385ca0782fc37cd5703eef23 248 Gene3D G3DSA:2.60.120.10 2 145 2.8E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS26020 50146722385ca0782fc37cd5703eef23 248 Pfam PF00027 Cyclic nucleotide-binding domain 33 117 3.6E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS26020 50146722385ca0782fc37cd5703eef23 248 SUPERFAMILY SSF46785 148 230 1.01E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26020 50146722385ca0782fc37cd5703eef23 248 SUPERFAMILY SSF51206 7 145 3.01E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS26020 50146722385ca0782fc37cd5703eef23 248 SMART SM00100 13 131 2.9E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS26020 50146722385ca0782fc37cd5703eef23 248 Gene3D G3DSA:1.10.10.10 146 232 1.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07260 56f0729131c066f870697d1f3ebd998b 282 Gene3D G3DSA:3.40.50.720 5 275 2.2E-41 T 29-03-2018 A616_RS07260 56f0729131c066f870697d1f3ebd998b 282 Pfam PF00899 ThiF family 14 253 4.7E-38 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS07260 56f0729131c066f870697d1f3ebd998b 282 SUPERFAMILY SSF69572 9 252 9.81E-45 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 Gene3D G3DSA:1.20.200.10 108 498 5.9E-62 T 29-03-2018 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 2.3E-18 T 29-03-2018 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 2.3E-18 T 29-03-2018 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 2.3E-18 T 29-03-2018 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 2.3E-18 T 29-03-2018 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 2.3E-18 T 29-03-2018 A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 1.3E-8 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 1.3E-8 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 1.3E-8 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 1.3E-8 T 29-03-2018 IPR000362 Fumarate lyase family A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 Pfam PF00206 Lyase 105 301 5.9E-28 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal A616_RS28645 06b535a8ab3d427ad49d3de9b7b60a5f 508 SUPERFAMILY SSF48557 33 464 2.51E-69 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS01740 27dcd0bd2208595488101ea600170f77 378 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 4.6E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS01740 27dcd0bd2208595488101ea600170f77 378 SUPERFAMILY SSF51735 156 340 6.31E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS01740 27dcd0bd2208595488101ea600170f77 378 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A616_RS01740 27dcd0bd2208595488101ea600170f77 378 SUPERFAMILY SSF50129 1 177 2.28E-60 T 29-03-2018 IPR011032 GroES-like A616_RS01740 27dcd0bd2208595488101ea600170f77 378 Pfam PF00107 Zinc-binding dehydrogenase 189 257 3.1E-9 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS01740 27dcd0bd2208595488101ea600170f77 378 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.4E-12 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated A616_RS01740 27dcd0bd2208595488101ea600170f77 378 Gene3D G3DSA:3.90.180.10 1 178 4.7E-50 T 29-03-2018 A616_RS01740 27dcd0bd2208595488101ea600170f77 378 Gene3D G3DSA:3.40.50.720 179 331 1.1E-22 T 29-03-2018 A616_RS07295 20112cf24a52dca5183fb8f6ab2ea11c 371 SUPERFAMILY SSF53383 10 363 9.63E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS07295 20112cf24a52dca5183fb8f6ab2ea11c 371 Gene3D G3DSA:3.40.640.10 42 253 8.1E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS07295 20112cf24a52dca5183fb8f6ab2ea11c 371 Gene3D G3DSA:3.90.1150.10 254 371 6.7E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS07295 20112cf24a52dca5183fb8f6ab2ea11c 371 Pfam PF00155 Aminotransferase class I and II 35 360 3.2E-36 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS07295 20112cf24a52dca5183fb8f6ab2ea11c 371 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 219 232 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A616_RS07295 20112cf24a52dca5183fb8f6ab2ea11c 371 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 12 361 7.1E-97 T 29-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 312 1.8E-13 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 Pfam PF00005 ABC transporter 41 196 7.8E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 SUPERFAMILY SSF52540 14 267 1.01E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 Gene3D G3DSA:3.40.50.300 10 348 1.3E-82 T 29-03-2018 A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 SMART SM00382 50 245 1.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12795 95f544ca9a736b2d0d2ce7fcb526977d 348 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 331 1.8E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS14420 45e808a5499dad1b416b1cea6ab63878 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 295 2.2E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS14420 45e808a5499dad1b416b1cea6ab63878 332 Gene3D G3DSA:1.10.3470.10 23 303 3.3E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS05350 ccca0236a54b2355eea56f9e7504d634 306 SUPERFAMILY SSF52540 3 222 9.27E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05350 ccca0236a54b2355eea56f9e7504d634 306 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS05350 ccca0236a54b2355eea56f9e7504d634 306 Gene3D G3DSA:3.40.50.300 1 264 1.0E-60 T 29-03-2018 A616_RS05350 ccca0236a54b2355eea56f9e7504d634 306 Pfam PF00005 ABC transporter 20 159 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS05350 ccca0236a54b2355eea56f9e7504d634 306 SMART SM00382 28 215 6.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15645 42d19d171cf6170a3e0812536045afd6 138 Pfam PF12802 MarR family 27 83 1.1E-8 T 29-03-2018 A616_RS15645 42d19d171cf6170a3e0812536045afd6 138 SUPERFAMILY SSF46785 8 135 8.59E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15645 42d19d171cf6170a3e0812536045afd6 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 3.9E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15645 42d19d171cf6170a3e0812536045afd6 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 3.9E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15645 42d19d171cf6170a3e0812536045afd6 138 Gene3D G3DSA:1.10.10.10 3 134 3.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15645 42d19d171cf6170a3e0812536045afd6 138 SMART SM00347 21 120 3.5E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS27410 d303e2b3fe790d5e39f8d72900a89885 290 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 37 270 5.1E-60 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related A616_RS15285 e7ed1f178866f99749f1169e3ae8186c 332 SUPERFAMILY SSF51735 4 92 8.7E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15285 e7ed1f178866f99749f1169e3ae8186c 332 Gene3D G3DSA:3.40.50.720 2 220 3.6E-10 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 SUPERFAMILY SSF111369 56 151 1.09E-9 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 Gene3D G3DSA:2.40.50.100 65 131 2.6E-14 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 Gene3D G3DSA:1.10.287.470 132 191 9.3E-7 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 SUPERFAMILY SSF111369 204 333 1.18E-8 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 SUPERFAMILY SSF111369 135 170 1.18E-8 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 326 8.2E-17 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 Gene3D G3DSA:2.40.50.100 213 300 0.0043 T 29-03-2018 A616_RS04505 76f8b814cb2c4b373b6af075187ce5ae 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 195 407 7.7E-38 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS31620 962e44d76c6473e4108b296e99e71c62 300 SUPERFAMILY SSF53335 73 233 2.79E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS31620 962e44d76c6473e4108b296e99e71c62 300 Pfam PF13489 Methyltransferase domain 83 229 5.1E-22 T 29-03-2018 A616_RS31620 962e44d76c6473e4108b296e99e71c62 300 Gene3D G3DSA:3.40.50.150 38 292 1.6E-30 T 29-03-2018 A616_RS10835 860730376c9f376d15341438742895c3 882 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 858 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 Pfam PF02272 DHHA1 domain 735 875 2.8E-31 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A616_RS10835 860730376c9f376d15341438742895c3 882 Gene3D G3DSA:1.20.120.330 701 828 2.7E-5 T 29-03-2018 A616_RS10835 860730376c9f376d15341438742895c3 882 Pfam PF01411 tRNA synthetases class II (A) 8 557 7.9E-210 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 SUPERFAMILY SSF55681 5 245 1.32E-88 T 29-03-2018 A616_RS10835 860730376c9f376d15341438742895c3 882 SMART SM00863 655 698 7.5E-21 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A616_RS10835 860730376c9f376d15341438742895c3 882 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 879 185.822 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A616_RS10835 860730376c9f376d15341438742895c3 882 Gene3D G3DSA:3.30.930.10 3 242 9.5E-96 T 29-03-2018 A616_RS10835 860730376c9f376d15341438742895c3 882 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 2.9E-18 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A616_RS10835 860730376c9f376d15341438742895c3 882 Gene3D G3DSA:3.30.980.10 556 700 3.7E-46 T 29-03-2018 A616_RS10835 860730376c9f376d15341438742895c3 882 SUPERFAMILY SSF55186 554 717 2.22E-52 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A616_RS10835 860730376c9f376d15341438742895c3 882 SUPERFAMILY SSF50447 455 554 1.01E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS10835 860730376c9f376d15341438742895c3 882 SUPERFAMILY SSF101353 246 458 6.93E-67 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A616_RS02075 1cfb1310b87898341d479780bae440d1 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS02075 1cfb1310b87898341d479780bae440d1 261 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 261 7.1E-112 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 A616_RS02075 1cfb1310b87898341d479780bae440d1 261 Gene3D G3DSA:3.40.50.720 45 261 8.9E-60 T 29-03-2018 A616_RS02075 1cfb1310b87898341d479780bae440d1 261 Gene3D G3DSA:3.40.50.720 1 44 1.3E-11 T 29-03-2018 A616_RS02075 1cfb1310b87898341d479780bae440d1 261 SUPERFAMILY SSF51735 7 260 4.41E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0061 T 29-03-2018 A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 7.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02075 1cfb1310b87898341d479780bae440d1 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 259 1.1E-66 T 29-03-2018 A616_RS05455 fc7b04197edaf2dcdbb0e4d1b14cc702 213 SUPERFAMILY SSF52540 4 212 3.86E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05455 fc7b04197edaf2dcdbb0e4d1b14cc702 213 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS05455 fc7b04197edaf2dcdbb0e4d1b14cc702 213 SMART SM00382 30 212 2.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS05455 fc7b04197edaf2dcdbb0e4d1b14cc702 213 Gene3D G3DSA:3.40.50.300 1 213 5.1E-65 T 29-03-2018 A616_RS05455 fc7b04197edaf2dcdbb0e4d1b14cc702 213 Pfam PF00005 ABC transporter 22 165 2.1E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS05475 c96e025537050445cbd1cc9c23058bb7 312 SUPERFAMILY SSF55347 123 277 9.81E-6 T 29-03-2018 A616_RS05475 c96e025537050445cbd1cc9c23058bb7 312 Gene3D G3DSA:3.40.50.720 1 141 1.0E-30 T 29-03-2018 A616_RS05475 c96e025537050445cbd1cc9c23058bb7 312 SUPERFAMILY SSF51735 1 180 5.11E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS05475 c96e025537050445cbd1cc9c23058bb7 312 Gene3D G3DSA:3.30.360.10 142 312 4.2E-13 T 29-03-2018 A616_RS05475 c96e025537050445cbd1cc9c23058bb7 312 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 117 9.3E-21 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS12570 3d26ac2ae28b6d1af61f82c4119c84c5 330 SUPERFAMILY SSF53850 26 252 3.67E-28 T 29-03-2018 A616_RS12570 3d26ac2ae28b6d1af61f82c4119c84c5 330 Pfam PF13379 NMT1-like family 27 259 2.2E-21 T 29-03-2018 A616_RS12570 3d26ac2ae28b6d1af61f82c4119c84c5 330 Gene3D G3DSA:3.40.190.10 24 130 2.9E-16 T 29-03-2018 A616_RS12570 3d26ac2ae28b6d1af61f82c4119c84c5 330 Gene3D G3DSA:3.40.190.10 131 327 1.5E-28 T 29-03-2018 A616_RS19440 51c9ad2af8c2cc6bca2bb0f7f5643fc4 305 SUPERFAMILY SSF56091 23 176 2.04E-22 T 29-03-2018 A616_RS19440 51c9ad2af8c2cc6bca2bb0f7f5643fc4 305 Gene3D G3DSA:3.30.470.30 35 135 5.4E-5 T 29-03-2018 A616_RS19440 51c9ad2af8c2cc6bca2bb0f7f5643fc4 305 Pfam PF09414 RNA ligase 27 189 3.2E-25 T 29-03-2018 IPR021122 RNA ligase domain, REL/Rln2 A616_RS24710 7ce9445e520ea9bcf2e38d7fbed18700 156 Pfam PF13599 Pentapeptide repeats (9 copies) 29 95 2.5E-7 T 29-03-2018 IPR001646 Pentapeptide repeat A616_RS24710 7ce9445e520ea9bcf2e38d7fbed18700 156 Pfam PF00805 Pentapeptide repeats (8 copies) 113 141 4.4E-4 T 29-03-2018 IPR001646 Pentapeptide repeat A616_RS24710 7ce9445e520ea9bcf2e38d7fbed18700 156 Gene3D G3DSA:2.160.20.80 2 148 6.1E-23 T 29-03-2018 A616_RS24710 7ce9445e520ea9bcf2e38d7fbed18700 156 SUPERFAMILY SSF141571 8 146 4.71E-22 T 29-03-2018 A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 SUPERFAMILY SSF74982 4 134 2.49E-51 T 29-03-2018 IPR023620 Small protein B A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 Gene3D G3DSA:2.40.280.10 11 129 2.5E-49 T 29-03-2018 IPR023620 Small protein B A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 11 134 1.0E-45 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 ProSitePatterns PS01317 SsrA-binding protein. 29 41 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 Pfam PF01668 SmpB protein 11 152 2.0E-60 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 TIGRFAM TIGR00086 smpB: SsrA-binding protein 11 151 1.8E-55 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 A616_RS28965 41e1a6d6f00c6b60f2a8cecba35ad3df 157 Hamap MF_00023 SsrA-binding protein [smpB]. 1 157 74.596 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 Pfam PF00667 FAD binding domain 236 433 2.5E-35 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 SUPERFAMILY SSF52218 64 210 6.67E-48 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 SUPERFAMILY SSF52343 453 608 2.49E-51 T 29-03-2018 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 Pfam PF00175 Oxidoreductase NAD-binding domain 466 572 4.5E-18 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 7 608 8.2E-256 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PIRSF PIRSF000207 1 608 1.4E-259 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 Gene3D G3DSA:2.40.30.10 228 447 1.0E-49 T 29-03-2018 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 SUPERFAMILY SSF63380 234 454 9.36E-64 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 395 402 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 557 565 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 274 284 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 428 437 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 465 484 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 534 550 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 503 514 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 490 499 4.6E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 Pfam PF00258 Flavodoxin 68 195 3.7E-32 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 Gene3D G3DSA:3.40.50.360 41 221 7.4E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00369 Flavodoxin signature 115 126 5.1E-15 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00369 Flavodoxin signature 67 80 5.1E-15 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00369 Flavodoxin signature 147 157 5.1E-15 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 PRINTS PR00369 Flavodoxin signature 171 190 5.1E-15 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A616_RS31995 22a6fa3019040e14e6a8e38f61f5a578 608 Gene3D G3DSA:3.40.50.80 462 608 1.3E-36 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 Gene3D G3DSA:2.120.10.60 452 585 0.13 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 Gene3D G3DSA:2.120.10.60 283 451 7.7E-13 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 Gene3D G3DSA:2.120.10.60 26 147 7.4E-11 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 SUPERFAMILY SSF69304 209 405 2.09E-14 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 Gene3D G3DSA:2.140.10.30 148 266 9.6E-8 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 TIGRFAM TIGR04275 beta_prop_Msarc: beta propeller repeat 78 112 2.5E-12 T 29-03-2018 IPR027618 Beta propeller repeat, Msarc-type A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 TIGRFAM TIGR04275 beta_prop_Msarc: beta propeller repeat 155 192 3.2E-11 T 29-03-2018 IPR027618 Beta propeller repeat, Msarc-type A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 SUPERFAMILY SSF69304 49 263 1.44E-20 T 29-03-2018 A616_RS21590 5b57510981f7c5cb0310de875fbfc45c 628 SUPERFAMILY SSF69304 330 547 3.4E-13 T 29-03-2018 A616_RS09055 a11796c92014c88221bf9fcefcd71176 212 Pfam PF10067 Predicted membrane protein (DUF2306) 56 202 1.9E-33 T 29-03-2018 IPR018750 Protein of unknown function DUF2306, membrane A616_RS09055 a11796c92014c88221bf9fcefcd71176 212 Gene3D G3DSA:1.10.287.70 33 143 2.1E-4 T 29-03-2018 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 SUPERFAMILY SSF46689 333 380 9.86E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 Gene3D G3DSA:3.40.50.2300 1 261 1.3E-28 T 29-03-2018 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 Gene3D G3DSA:1.10.10.60 350 394 2.3E-13 T 29-03-2018 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 SMART SM00448 3 121 5.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 334 376 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 349 364 1.1E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 364 380 1.1E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 SUPERFAMILY SSF52172 3 113 1.85E-26 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 SMART SM00342 297 380 2.5E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 SUPERFAMILY SSF46689 281 330 4.12E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 Gene3D G3DSA:1.10.10.10 328 349 0.073 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 Pfam PF12833 Helix-turn-helix domain 304 380 4.9E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 Gene3D G3DSA:1.10.10.60 262 327 1.4E-12 T 29-03-2018 A616_RS31785 f95838ab9f301f2ccfca962677e5dd1a 398 Pfam PF00072 Response regulator receiver domain 5 108 1.8E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS06695 db0d61cc5a58d845fd4d3db351eecf0d 392 Pfam PF00155 Aminotransferase class I and II 35 383 8.4E-70 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS06695 db0d61cc5a58d845fd4d3db351eecf0d 392 Gene3D G3DSA:3.40.640.10 50 299 1.5E-66 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS06695 db0d61cc5a58d845fd4d3db351eecf0d 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A616_RS06695 db0d61cc5a58d845fd4d3db351eecf0d 392 Gene3D G3DSA:3.90.1150.10 300 391 2.2E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS06695 db0d61cc5a58d845fd4d3db351eecf0d 392 SUPERFAMILY SSF53383 10 390 1.09E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS05585 b7e88f7f1398ae9f6c3e6af891525ae6 176 SUPERFAMILY SSF55729 23 158 3.3E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS05585 b7e88f7f1398ae9f6c3e6af891525ae6 176 Gene3D G3DSA:3.40.630.30 2 170 2.3E-17 T 29-03-2018 A616_RS05585 b7e88f7f1398ae9f6c3e6af891525ae6 176 Pfam PF13302 Acetyltransferase (GNAT) domain 12 133 9.7E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS01590 425ffd824aeff344e13b8e26a5560c8c 195 PIRSF PIRSF029886 2 194 4.4E-49 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A616_RS01590 425ffd824aeff344e13b8e26a5560c8c 195 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 190 1.9E-63 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A616_RS01590 425ffd824aeff344e13b8e26a5560c8c 195 SMART SM01251 17 191 2.0E-103 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 A616_RS12500 a14aca9bbd7c8a5f580bb8c431861ba3 327 SUPERFAMILY SSF53807 51 320 1.37E-52 T 29-03-2018 A616_RS12500 a14aca9bbd7c8a5f580bb8c431861ba3 327 Pfam PF01497 Periplasmic binding protein 118 300 4.0E-26 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS12500 a14aca9bbd7c8a5f580bb8c431861ba3 327 Gene3D G3DSA:3.40.50.1980 37 165 4.3E-20 T 29-03-2018 A616_RS12500 a14aca9bbd7c8a5f580bb8c431861ba3 327 Gene3D G3DSA:3.40.50.1980 166 325 2.8E-32 T 29-03-2018 A616_RS11100 0dd2c0987914cf0eb706ab72c4de3ae6 261 Gene3D G3DSA:3.60.21.10 2 260 1.5E-40 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS11100 0dd2c0987914cf0eb706ab72c4de3ae6 261 SUPERFAMILY SSF56300 3 228 1.9E-43 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS11100 0dd2c0987914cf0eb706ab72c4de3ae6 261 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 67 72 - T 29-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS11100 0dd2c0987914cf0eb706ab72c4de3ae6 261 PRINTS PR00114 Serine/threonine phosphatase family signature 33 60 6.9E-5 T 29-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS11100 0dd2c0987914cf0eb706ab72c4de3ae6 261 PRINTS PR00114 Serine/threonine phosphatase family signature 2 29 6.9E-5 T 29-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS11100 0dd2c0987914cf0eb706ab72c4de3ae6 261 Pfam PF00149 Calcineurin-like phosphoesterase 4 211 2.8E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS14600 70040429354268d906a909f9de1b8a3f 581 Gene3D G3DSA:1.20.1560.10 1 316 1.6E-66 T 29-03-2018 A616_RS14600 70040429354268d906a909f9de1b8a3f 581 Pfam PF00005 ABC transporter 349 498 2.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14600 70040429354268d906a909f9de1b8a3f 581 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14600 70040429354268d906a909f9de1b8a3f 581 Gene3D G3DSA:3.40.50.300 318 572 1.3E-78 T 29-03-2018 A616_RS14600 70040429354268d906a909f9de1b8a3f 581 SMART SM00382 358 544 6.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14600 70040429354268d906a909f9de1b8a3f 581 SUPERFAMILY SSF90123 3 319 7.06E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS14600 70040429354268d906a909f9de1b8a3f 581 SUPERFAMILY SSF52540 322 569 1.91E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14600 70040429354268d906a909f9de1b8a3f 581 Pfam PF00664 ABC transporter transmembrane region 17 287 1.4E-56 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 SUPERFAMILY SSF58104 238 267 2.35E-73 T 29-03-2018 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 SUPERFAMILY SSF58104 300 569 2.35E-73 T 29-03-2018 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 Gene3D G3DSA:1.10.287.950 308 514 3.4E-56 T 29-03-2018 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 338 522 8.1E-53 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 Gene3D G3DSA:1.20.120.30 26 190 6.8E-10 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 Pfam PF00672 HAMP domain 212 259 5.8E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 SMART SM00304 212 265 1.7E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 184 1.3E-31 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 308 337 1.9E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 421 450 1.9E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 SMART SM00283 294 569 3.1E-85 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS18705 5d7ae9c2312e7bb0b9ca549ad872ff68 570 Gene3D G3DSA:1.10.287.950 515 570 2.4E-8 T 29-03-2018 A616_RS12965 c1a4abbc3181d09bf4ddb35b13959c01 187 Gene3D G3DSA:3.40.50.360 1 186 4.5E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS12965 c1a4abbc3181d09bf4ddb35b13959c01 187 SUPERFAMILY SSF52218 1 177 1.55E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS12965 c1a4abbc3181d09bf4ddb35b13959c01 187 Pfam PF03358 NADPH-dependent FMN reductase 1 139 4.0E-36 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A616_RS27270 1f75a583b69a139d04048fbc412d5572 230 SMART SM00882 5 216 8.4E-99 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS27270 1f75a583b69a139d04048fbc412d5572 230 Gene3D G3DSA:3.40.1080.10 1 230 6.2E-101 T 29-03-2018 A616_RS27270 1f75a583b69a139d04048fbc412d5572 230 SUPERFAMILY SSF100950 3 227 6.8E-91 T 29-03-2018 A616_RS27270 1f75a583b69a139d04048fbc412d5572 230 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS27270 1f75a583b69a139d04048fbc412d5572 230 Pfam PF01144 Coenzyme A transferase 7 215 1.1E-80 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS27270 1f75a583b69a139d04048fbc412d5572 230 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 215 2.7E-82 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 Gene3D G3DSA:1.10.10.10 1 83 2.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 Gene3D G3DSA:3.40.190.10 90 180 3.8E-22 T 29-03-2018 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 SUPERFAMILY SSF53850 90 294 6.73E-45 T 29-03-2018 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 Pfam PF03466 LysR substrate binding domain 90 292 3.0E-48 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 Gene3D G3DSA:3.40.190.10 181 267 1.7E-25 T 29-03-2018 A616_RS15090 880757c698fdaecc5377db5160fa6ccf 300 SUPERFAMILY SSF46785 1 83 9.61E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07820 5ca8dd6637fa87a5c808a0a435e11fcb 262 SUPERFAMILY SSF52172 145 262 9.11E-30 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS07820 5ca8dd6637fa87a5c808a0a435e11fcb 262 SMART SM00448 146 258 7.0E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07820 5ca8dd6637fa87a5c808a0a435e11fcb 262 Pfam PF00072 Response regulator receiver domain 148 258 1.7E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07820 5ca8dd6637fa87a5c808a0a435e11fcb 262 Gene3D G3DSA:3.40.50.2300 137 262 1.0E-30 T 29-03-2018 A616_RS28570 570c689254adaa6ca010d78e70140366 371 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 364 2.2E-104 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A616_RS28570 570c689254adaa6ca010d78e70140366 371 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 366 56.794 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A616_RS28570 570c689254adaa6ca010d78e70140366 371 Gene3D G3DSA:3.90.1150.10 257 361 1.5E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS28570 570c689254adaa6ca010d78e70140366 371 Gene3D G3DSA:3.40.640.10 50 256 1.0E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS28570 570c689254adaa6ca010d78e70140366 371 Pfam PF00155 Aminotransferase class I and II 37 361 2.3E-61 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS28570 570c689254adaa6ca010d78e70140366 371 SUPERFAMILY SSF53383 20 366 8.97E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS04520 a52d5fb493845e920e886442ae6d4d0e 255 SMART SM00382 35 242 8.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04520 a52d5fb493845e920e886442ae6d4d0e 255 SUPERFAMILY SSF52540 5 227 1.26E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04520 a52d5fb493845e920e886442ae6d4d0e 255 Pfam PF00005 ABC transporter 26 174 4.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS04520 a52d5fb493845e920e886442ae6d4d0e 255 Gene3D G3DSA:3.40.50.300 1 248 1.6E-66 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Gene3D G3DSA:1.10.287.950 430 674 3.8E-36 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Gene3D G3DSA:1.10.287.950 333 429 2.3E-10 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Gene3D G3DSA:3.30.450.20 179 293 2.8E-23 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 SUPERFAMILY SSF58104 334 368 1.57E-50 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 SUPERFAMILY SSF58104 401 669 1.57E-50 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 467 620 5.3E-23 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 SMART SM00283 395 670 4.8E-23 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Gene3D G3DSA:3.30.450.20 61 178 1.1E-12 T 29-03-2018 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Pfam PF02743 Cache domain 51 276 1.5E-30 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 SMART SM00304 314 366 1.4E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS02785 d657ee7ef9de1f30e56b1634d96dfdbd 682 Pfam PF00672 HAMP domain 314 362 1.7E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 Pfam PF12823 Domain of unknown function (DUF3817) 8 93 1.6E-19 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 10 92 7.1E-25 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 Gene3D G3DSA:1.20.1250.20 104 295 2.6E-29 T 29-03-2018 A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 Gene3D G3DSA:1.20.1250.20 306 490 3.8E-24 T 29-03-2018 A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 SUPERFAMILY SSF103473 107 481 5.89E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 Pfam PF07690 Major Facilitator Superfamily 312 473 4.5E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS08260 75899b4127cdbade2fe1df0d7494d0fe 490 Pfam PF07690 Major Facilitator Superfamily 113 294 1.1E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 Gene3D G3DSA:3.50.50.60 1 122 8.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 Gene3D G3DSA:3.50.50.60 123 153 0.028 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 SUPERFAMILY SSF51905 1 305 1.34E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 288 5.2E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.5E-5 T 29-03-2018 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.5E-5 T 29-03-2018 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 Gene3D G3DSA:3.50.50.60 154 303 1.0E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 2.5E-6 T 29-03-2018 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 273 2.5E-6 T 29-03-2018 A616_RS26345 0e1603ca7b88facd71ac518cc646133b 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.5E-6 T 29-03-2018 A616_RS18685 88e1f4a5933dbf0d8d9858990b1e6cb5 352 SUPERFAMILY SSF53850 61 275 3.04E-10 T 29-03-2018 A616_RS18685 88e1f4a5933dbf0d8d9858990b1e6cb5 352 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 71 349 1.9E-34 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A616_RS18685 88e1f4a5933dbf0d8d9858990b1e6cb5 352 Gene3D G3DSA:3.40.190.10 151 262 2.0E-15 T 29-03-2018 A616_RS18685 88e1f4a5933dbf0d8d9858990b1e6cb5 352 PIRSF PIRSF017082 15 352 5.6E-104 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 PIRSF PIRSF038984 1 103 1.4E-6 T 29-03-2018 IPR028348 FAD dependent protein A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 PIRSF PIRSF038984 124 477 3.8E-22 T 29-03-2018 IPR028348 FAD dependent protein A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 Pfam PF01134 Glucose inhibited division protein A 118 476 1.5E-7 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 SUPERFAMILY SSF51905 157 244 3.38E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 SUPERFAMILY SSF51905 3 114 3.38E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 SUPERFAMILY SSF51905 425 475 3.38E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS30580 26d67b4f76df7fc16ba67d0e20f5fdf1 477 Gene3D G3DSA:3.50.50.60 1 477 1.1E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 Pfam PF12848 ABC transporter 232 322 3.0E-22 T 29-03-2018 IPR032781 ABC-transporter extension domain A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 Pfam PF00005 ABC transporter 19 193 1.7E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 Pfam PF00005 ABC transporter 354 481 2.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 SUPERFAMILY SSF52540 320 544 7.61E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 SUPERFAMILY SSF52540 7 246 2.63E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 SMART SM00382 361 533 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 SMART SM00382 28 237 4.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 Gene3D G3DSA:3.40.50.300 2 332 3.5E-55 T 29-03-2018 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 Gene3D G3DSA:3.40.50.300 333 631 2.8E-48 T 29-03-2018 A616_RS23780 fc6ec3b699d5f6d36cf2c401d31cbb22 641 Pfam PF16326 ABC transporter C-terminal domain 582 640 4.2E-9 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A616_RS15905 a9a49d745f9006d1a81d4a18edd29245 318 SUPERFAMILY SSF53686 6 316 2.1E-84 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS15905 a9a49d745f9006d1a81d4a18edd29245 318 Gene3D G3DSA:3.40.50.1100 145 318 1.1E-41 T 29-03-2018 A616_RS15905 a9a49d745f9006d1a81d4a18edd29245 318 Gene3D G3DSA:3.40.50.1100 23 144 5.0E-29 T 29-03-2018 A616_RS15905 a9a49d745f9006d1a81d4a18edd29245 318 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 305 1.6E-62 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS11125 01e43db7e1bba178dc3720dbe6c5bf00 123 Pfam PF03734 L,D-transpeptidase catalytic domain 9 120 6.2E-22 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A616_RS11125 01e43db7e1bba178dc3720dbe6c5bf00 123 SUPERFAMILY SSF141523 4 121 6.54E-34 T 29-03-2018 A616_RS11125 01e43db7e1bba178dc3720dbe6c5bf00 123 Gene3D G3DSA:2.40.440.10 1 122 6.1E-34 T 29-03-2018 A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.3E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.3E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15410 536d668d02fed67920775968eb0919f7 247 Gene3D G3DSA:3.40.50.720 44 246 3.6E-64 T 29-03-2018 A616_RS15410 536d668d02fed67920775968eb0919f7 247 Gene3D G3DSA:3.40.50.720 1 43 1.4E-9 T 29-03-2018 A616_RS15410 536d668d02fed67920775968eb0919f7 247 SUPERFAMILY SSF51735 4 245 7.35E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15410 536d668d02fed67920775968eb0919f7 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 1.0E-68 T 29-03-2018 A616_RS27505 12e7a12ad444e004283d5aeb6b4cb9db 259 Gene3D G3DSA:3.90.226.10 1 219 3.4E-70 T 29-03-2018 A616_RS27505 12e7a12ad444e004283d5aeb6b4cb9db 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS27505 12e7a12ad444e004283d5aeb6b4cb9db 259 SUPERFAMILY SSF52096 1 259 2.39E-90 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS27505 12e7a12ad444e004283d5aeb6b4cb9db 259 Gene3D G3DSA:1.10.12.10 220 257 6.5E-17 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS27505 12e7a12ad444e004283d5aeb6b4cb9db 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 258 1.1E-66 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 Gene3D G3DSA:2.30.40.10 27 92 9.8E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 SUPERFAMILY SSF51556 88 338 7.56E-16 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 Pfam PF13382 Adenine deaminase C-terminal domain 432 596 3.5E-52 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 Gene3D G3DSA:3.20.20.140 93 288 1.9E-5 T 29-03-2018 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 SUPERFAMILY SSF51338 24 88 2.34E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 SUPERFAMILY SSF51338 343 384 2.34E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 Hamap MF_01518 Adenine deaminase [ade]. 31 605 32.524 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 Gene3D G3DSA:2.30.40.10 289 384 4.6E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS08540 c22fb73833fd595b473cd5a0c59c8bae 609 Pfam PF01979 Amidohydrolase family 85 375 2.1E-17 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 SUPERFAMILY SSF160240 210 287 5.89E-19 T 29-03-2018 A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 SUPERFAMILY SSF161111 7 208 3.14E-56 T 29-03-2018 A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 Pfam PF16916 Dimerisation domain of Zinc Transporter 211 287 1.7E-18 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 Gene3D G3DSA:1.20.1510.10 10 205 4.6E-45 T 29-03-2018 A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 Pfam PF01545 Cation efflux family 15 206 2.7E-51 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 Gene3D G3DSA:3.30.70.1350 206 289 2.0E-19 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A616_RS20375 4c0bda4a7e089a588bb2f37833d145f1 293 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 288 8.4E-76 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF14579 Helix-hairpin-helix motif 1348 1427 4.7E-9 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 418 634 4.8E-36 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Gene3D G3DSA:1.20.5.140 570 589 1.3E-6 T 29-03-2018 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 822 1239 3.3E-98 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF02811 PHP domain 332 694 2.8E-50 T 29-03-2018 IPR004013 PHP domain GO:0003824 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Gene3D G3DSA:3.20.20.150 317 420 5.8E-4 T 29-03-2018 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 SMART SM00481 331 398 1.2E-26 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Gene3D G3DSA:3.30.420.10 421 569 1.4E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 SUPERFAMILY SSF53098 420 874 3.64E-97 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1434 409.958 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF14480 DNA polymerase III polC-type N-terminus I 10 81 2.4E-17 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF01336 OB-fold nucleic acid binding domain 237 301 6.2E-7 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 SUPERFAMILY SSF50249 232 317 4.28E-9 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Gene3D G3DSA:2.40.50.140 217 316 8.8E-23 T 29-03-2018 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF00929 Exonuclease 422 577 3.6E-37 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Gene3D G3DSA:1.10.150.280 1370 1421 8.6E-4 T 29-03-2018 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Gene3D G3DSA:3.20.20.140 600 756 5.3E-15 T 29-03-2018 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 SMART SM00479 420 586 1.1E-50 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 208 3.1E-7 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS19825 7f149438b1efe79190409b677de35cc5 1434 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 228 1434 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 SMART SM00878 335 440 2.5E-51 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 SUPERFAMILY SSF52440 2 112 1.44E-44 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 Pfam PF02785 Biotin carboxylase C-terminal domain 335 440 2.6E-37 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 Gene3D G3DSA:3.30.1490.20 123 208 5.9E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 SUPERFAMILY SSF56059 114 326 1.1E-66 T 29-03-2018 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 8.5E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 Gene3D G3DSA:3.40.50.20 1 122 8.7E-50 T 29-03-2018 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 Gene3D G3DSA:3.30.470.20 209 442 3.7E-101 T 29-03-2018 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 2.2E-78 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS21405 9362468fe8ac6ee07e3ea0664adabcd2 451 SUPERFAMILY SSF51246 332 441 1.46E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A616_RS28505 39b8bb6b6616045e4eb1dc970d6020e2 318 Gene3D G3DSA:3.60.110.10 1 317 1.3E-85 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS28505 39b8bb6b6616045e4eb1dc970d6020e2 318 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 169 182 - T 29-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 A616_RS28505 39b8bb6b6616045e4eb1dc970d6020e2 318 SUPERFAMILY SSF56317 7 307 9.16E-82 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS28505 39b8bb6b6616045e4eb1dc970d6020e2 318 Pfam PF00795 Carbon-nitrogen hydrolase 9 283 1.7E-59 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS21395 055d55f9b759a099a7ff09159c575191 299 Pfam PF00682 HMGL-like 2 276 4.8E-53 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS21395 055d55f9b759a099a7ff09159c575191 299 Gene3D G3DSA:3.20.20.70 1 295 1.7E-101 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS21395 055d55f9b759a099a7ff09159c575191 299 SUPERFAMILY SSF51569 2 287 6.15E-72 T 29-03-2018 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 Pfam PF01546 Peptidase family M20/M25/M40 86 473 2.2E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 SUPERFAMILY SSF55031 186 385 1.1E-38 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 116 155 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 Gene3D G3DSA:3.40.630.10 5 186 1.2E-25 T 29-03-2018 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 Gene3D G3DSA:3.30.70.360 286 383 9.7E-26 T 29-03-2018 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 472 6.6E-148 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 SUPERFAMILY SSF53187 5 186 4.29E-62 T 29-03-2018 A616_RS10175 56ff63b97ee5596e26fd9b28b1a7a94d 477 SUPERFAMILY SSF53187 394 476 4.29E-62 T 29-03-2018 A616_RS03245 1460d974daff7f1baaf1cf897e79b2c7 256 SUPERFAMILY SSF52540 3 224 1.69E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03245 1460d974daff7f1baaf1cf897e79b2c7 256 Pfam PF00005 ABC transporter 22 170 2.3E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS03245 1460d974daff7f1baaf1cf897e79b2c7 256 SMART SM00382 31 219 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03245 1460d974daff7f1baaf1cf897e79b2c7 256 Gene3D G3DSA:3.40.50.300 1 237 1.0E-62 T 29-03-2018 A616_RS29940 a4aba0a8d5eaffe07dde8a3a57f21c71 69 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 11 64 1.3E-15 T 29-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter A616_RS14825 2c22819a11011e62633fc25bad5bc907 300 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 144 272 9.8E-44 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A616_RS14825 2c22819a11011e62633fc25bad5bc907 300 Gene3D G3DSA:3.30.1380.10 113 285 8.0E-37 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS14825 2c22819a11011e62633fc25bad5bc907 300 SUPERFAMILY SSF55166 129 279 6.54E-39 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS12070 fdcb22bce836f968cb70d2e4b212e7ff 169 SUPERFAMILY SSF54637 1 153 1.2E-48 T 29-03-2018 IPR029069 HotDog domain A616_RS12070 fdcb22bce836f968cb70d2e4b212e7ff 169 Pfam PF03061 Thioesterase superfamily 25 98 4.2E-20 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS12070 fdcb22bce836f968cb70d2e4b212e7ff 169 Gene3D G3DSA:3.10.129.10 1 155 1.2E-50 T 29-03-2018 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SMART SM00889 409 523 4.7E-22 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Pfam PF00679 Elongation factor G C-terminus 526 607 1.6E-16 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SMART SM00838 525 610 1.2E-5 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SUPERFAMILY SSF54211 408 523 2.66E-27 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SUPERFAMILY SSF54980 526 607 2.25E-16 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Gene3D G3DSA:2.40.30.10 228 329 1.5E-11 T 29-03-2018 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SUPERFAMILY SSF52540 3 227 1.03E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SUPERFAMILY SSF54980 335 410 2.09E-11 T 29-03-2018 IPR035647 EF-G domain III/V-like A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Gene3D G3DSA:3.40.50.300 1 227 4.2E-35 T 29-03-2018 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 2.7E-7 T 29-03-2018 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 206 228 2.7E-7 T 29-03-2018 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 146 2.2E-18 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Pfam PF03764 Elongation factor G, domain IV 408 523 8.1E-18 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Pfam PF00009 Elongation factor Tu GTP binding domain 4 228 8.1E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Gene3D G3DSA:3.30.230.10 422 538 2.8E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.7E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.7E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.7E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.7E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.7E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Gene3D G3DSA:3.30.70.240 539 614 1.8E-15 T 29-03-2018 A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 SUPERFAMILY SSF50447 224 333 4.59E-12 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS16185 2dbe479dce0e18f9e0135e3fb727e716 651 Gene3D G3DSA:3.30.70.870 331 421 3.7E-16 T 29-03-2018 A616_RS15600 791681e84e7a555dc7ff3c028d2f14e7 320 Pfam PF01966 HD domain 212 287 5.0E-6 T 29-03-2018 IPR006674 HD domain A616_RS15600 791681e84e7a555dc7ff3c028d2f14e7 320 SUPERFAMILY SSF52540 2 124 1.56E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15600 791681e84e7a555dc7ff3c028d2f14e7 320 Gene3D G3DSA:3.40.50.300 2 140 1.0E-19 T 29-03-2018 A616_RS15600 791681e84e7a555dc7ff3c028d2f14e7 320 SUPERFAMILY SSF109604 187 291 3.14E-18 T 29-03-2018 A616_RS15600 791681e84e7a555dc7ff3c028d2f14e7 320 Pfam PF13671 AAA domain 5 133 2.1E-23 T 29-03-2018 A616_RS15600 791681e84e7a555dc7ff3c028d2f14e7 320 Gene3D G3DSA:1.10.3090.10 141 317 1.2E-14 T 29-03-2018 A616_RS00610 15b1095f474498224cd1d62d0f89974d 216 Pfam PF08241 Methyltransferase domain 48 161 2.6E-13 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS00610 15b1095f474498224cd1d62d0f89974d 216 SUPERFAMILY SSF53335 23 181 3.93E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS00610 15b1095f474498224cd1d62d0f89974d 216 Gene3D G3DSA:3.40.50.150 29 190 2.1E-21 T 29-03-2018 A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 Pfam PF02743 Cache domain 51 291 6.6E-16 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 601 7.3E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 Pfam PF00672 HAMP domain 330 377 2.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 Gene3D G3DSA:3.30.565.10 355 602 5.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 SMART SM00304 329 381 3.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 Gene3D G3DSA:3.30.450.20 178 308 4.3E-7 T 29-03-2018 A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 SMART SM00387 487 603 2.5E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 SUPERFAMILY SSF55874 449 601 6.02E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 SUPERFAMILY SSF158472 330 380 4.45E-10 T 29-03-2018 A616_RS25550 e6bd006686426e1903ddb48f9d163c9c 618 Pfam PF06580 Histidine kinase 393 472 8.7E-26 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 PIRSF PIRSF000770 5 260 6.1E-41 T 29-03-2018 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 SUPERFAMILY SSF88946 8 103 3.14E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 Pfam PF04539 Sigma-70 region 3 111 169 2.8E-6 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 31 254 7.4E-79 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 Gene3D G3DSA:1.10.10.10 104 151 6.8E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 Pfam PF04542 Sigma-70 region 2 31 103 2.5E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 PRINTS PR00046 Major sigma-70 factor signature 224 239 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 PRINTS PR00046 Major sigma-70 factor signature 58 71 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 PRINTS PR00046 Major sigma-70 factor signature 82 90 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 PRINTS PR00046 Major sigma-70 factor signature 239 250 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 PRINTS PR00046 Major sigma-70 factor signature 207 219 3.9E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 58 71 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 Gene3D G3DSA:1.10.10.10 197 261 1.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 Pfam PF04545 Sigma-70, region 4 204 251 1.6E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 224 250 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 SUPERFAMILY SSF88659 104 171 8.28E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 Gene3D G3DSA:1.10.1740.10 15 101 1.0E-20 T 29-03-2018 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 254 6.9E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS19900 50f3738822792e75fbfea9fd677b4fd7 262 SUPERFAMILY SSF88659 168 257 1.46E-21 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23385 6e8050e33e6b1eebf0eb043a3cb14312 343 SUPERFAMILY SSF55729 155 304 4.48E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS23385 6e8050e33e6b1eebf0eb043a3cb14312 343 Pfam PF13480 Acetyltransferase (GNAT) domain 153 283 3.9E-11 T 29-03-2018 A616_RS23385 6e8050e33e6b1eebf0eb043a3cb14312 343 Gene3D G3DSA:3.40.630.30 120 302 2.0E-25 T 29-03-2018 A616_RS25240 86ccf3b910b4d5afbd4c159aa97932b2 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 7 58 6.1E-9 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 Pfam PF01022 Bacterial regulatory protein, arsR family 26 72 1.0E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 SUPERFAMILY SSF46785 13 86 3.12E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.1E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.1E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.1E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 Gene3D G3DSA:1.10.10.10 1 99 4.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 SMART SM00419 31 83 0.0028 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS20980 3bd02d0635cdcd58eb84916b72ac93ff 105 SMART SM00418 19 98 7.4E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS12590 dd690a324c91c653ac2c0a4c38dfb624 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 8 24 3.5E-7 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS12590 dd690a324c91c653ac2c0a4c38dfb624 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 28 3.3E-6 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Gene3D G3DSA:3.30.70.250 3 87 9.0E-38 T 29-03-2018 A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Gene3D G3DSA:2.160.10.10 88 236 2.8E-43 T 29-03-2018 A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 118 8.2E-4 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 1.1E-7 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 1.3E-8 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 1.4E-117 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 SUPERFAMILY SSF51161 88 224 9.56E-49 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 46.254 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 86 2.4E-35 T 29-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 A616_RS21645 70453f294f96b0ee32c476d5d22857ee 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A616_RS31040 b1fd93c2892acec921e5c2446c9838e5 396 SUPERFAMILY SSF103473 7 393 8.89E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS31040 b1fd93c2892acec921e5c2446c9838e5 396 Gene3D G3DSA:1.20.1250.20 3 193 6.4E-19 T 29-03-2018 A616_RS31040 b1fd93c2892acec921e5c2446c9838e5 396 Gene3D G3DSA:1.20.1250.20 198 394 1.4E-8 T 29-03-2018 A616_RS31040 b1fd93c2892acec921e5c2446c9838e5 396 Pfam PF07690 Major Facilitator Superfamily 11 355 2.4E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 152 24.185 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 Gene3D G3DSA:2.30.30.180 88 150 3.7E-15 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 Gene3D G3DSA:3.30.300.70 1 81 2.3E-25 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 SUPERFAMILY SSF75420 3 84 1.27E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 SUPERFAMILY SSF74942 85 152 8.37E-16 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 Pfam PF17384 RimP C-terminal SH3 domain 87 152 2.1E-13 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A616_RS19820 83c74695f49fee6c65f54522917a37ab 152 Pfam PF02576 RimP N-terminal domain 11 84 1.6E-29 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A616_RS14860 b8b78f78f8201be31af835b2935a8273 149 Gene3D G3DSA:2.40.50.100 31 148 6.4E-9 T 29-03-2018 A616_RS14860 b8b78f78f8201be31af835b2935a8273 149 SUPERFAMILY SSF51230 75 146 1.13E-8 T 29-03-2018 IPR011053 Single hybrid motif A616_RS14860 b8b78f78f8201be31af835b2935a8273 149 Pfam PF00364 Biotin-requiring enzyme 79 145 1.0E-6 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS17780 494f72a010a31804c08ec1af5f811913 173 PRINTS PR01576 Peptide deformylase signature 34 63 2.1E-25 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 PRINTS PR01576 Peptide deformylase signature 87 98 2.1E-25 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 PRINTS PR01576 Peptide deformylase signature 99 117 2.1E-25 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 PRINTS PR01576 Peptide deformylase signature 118 147 2.1E-25 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 Gene3D G3DSA:3.90.45.10 1 171 1.5E-53 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 Hamap MF_00163 Peptide deformylase [def]. 2 160 26.97 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 PIRSF PIRSF004749 1 172 1.2E-45 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 157 3.0E-42 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 Pfam PF01327 Polypeptide deformylase 4 147 1.4E-44 T 29-03-2018 IPR023635 Peptide deformylase A616_RS17780 494f72a010a31804c08ec1af5f811913 173 SUPERFAMILY SSF56420 4 159 1.7E-50 T 29-03-2018 IPR023635 Peptide deformylase A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 Gene3D G3DSA:3.40.50.1370 8 160 1.8E-58 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 Gene3D G3DSA:3.40.50.1370 161 322 2.9E-63 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 SUPERFAMILY SSF53671 17 322 5.37E-109 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 21 322 1.5E-132 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 288 311 3.3E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 148 159 3.3E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 276 285 3.3E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 66 85 3.3E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 240 250 1.3E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 137 151 1.3E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 302 313 1.3E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 97 110 1.3E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 PRINTS PR00102 Ornithine carbamoyltransferase signature 64 78 1.3E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 66 73 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 167 321 4.9E-59 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 20 323 81.668 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A616_RS29345 2f0e7b34d04992ae63eb71b3be622b7b 323 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 161 2.7E-49 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A616_RS09230 8319b92a98a83105bb861fb4e100da75 460 SUPERFAMILY SSF103473 253 455 1.57E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09230 8319b92a98a83105bb861fb4e100da75 460 SUPERFAMILY SSF103473 4 188 1.57E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09230 8319b92a98a83105bb861fb4e100da75 460 Pfam PF07690 Major Facilitator Superfamily 13 414 2.8E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS09230 8319b92a98a83105bb861fb4e100da75 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS09230 8319b92a98a83105bb861fb4e100da75 460 Gene3D G3DSA:1.20.1250.20 3 197 4.6E-31 T 29-03-2018 A616_RS09230 8319b92a98a83105bb861fb4e100da75 460 Gene3D G3DSA:1.20.1250.20 263 460 1.8E-29 T 29-03-2018 A616_RS07195 559e8ff2bccc2df38032e480b8219611 217 SUPERFAMILY SSF161098 13 199 2.49E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07195 559e8ff2bccc2df38032e480b8219611 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 213 6.6E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07195 559e8ff2bccc2df38032e480b8219611 217 Gene3D G3DSA:1.10.3720.10 2 217 2.2E-49 T 29-03-2018 A616_RS07195 559e8ff2bccc2df38032e480b8219611 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 2.5E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS15065 dd14d49ec3288a253212f25428e992b3 261 SUPERFAMILY SSF52540 1 240 4.17E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15065 dd14d49ec3288a253212f25428e992b3 261 Pfam PF00005 ABC transporter 21 169 1.0E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15065 dd14d49ec3288a253212f25428e992b3 261 Gene3D G3DSA:3.40.50.300 1 255 1.4E-74 T 29-03-2018 A616_RS15065 dd14d49ec3288a253212f25428e992b3 261 SMART SM00382 30 218 5.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15065 dd14d49ec3288a253212f25428e992b3 261 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28640 38f48d3fe43df772546715791ff091c9 350 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 291 2.2E-46 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS28640 38f48d3fe43df772546715791ff091c9 350 Gene3D G3DSA:3.40.50.1100 39 139 7.3E-19 T 29-03-2018 A616_RS28640 38f48d3fe43df772546715791ff091c9 350 Gene3D G3DSA:3.40.50.1100 140 305 1.1E-35 T 29-03-2018 A616_RS28640 38f48d3fe43df772546715791ff091c9 350 SUPERFAMILY SSF53686 4 306 2.88E-66 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS09120 15d85723abed9931231dbbf2f0499356 141 SUPERFAMILY SSF46785 2 139 4.59E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09120 15d85723abed9931231dbbf2f0499356 141 Pfam PF01047 MarR family 31 88 2.7E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09120 15d85723abed9931231dbbf2f0499356 141 Gene3D G3DSA:1.10.10.10 4 137 1.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09120 15d85723abed9931231dbbf2f0499356 141 SMART SM00347 24 124 2.9E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09120 15d85723abed9931231dbbf2f0499356 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 2.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09120 15d85723abed9931231dbbf2f0499356 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 2.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09120 15d85723abed9931231dbbf2f0499356 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 2.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09120 15d85723abed9931231dbbf2f0499356 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 2.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SUPERFAMILY SSF55666 145 236 2.95E-26 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 7.9E-22 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF01138 3' exoribonuclease family, domain 1 326 459 6.9E-19 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Gene3D G3DSA:2.40.50.140 623 704 1.2E-23 T 29-03-2018 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SUPERFAMILY SSF50249 625 705 1.04E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SUPERFAMILY SSF54791 560 645 1.4E-22 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 4.3E-12 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF03725 3' exoribonuclease family, domain 2 462 532 9.0E-5 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SMART SM00322 557 622 7.9E-11 T 29-03-2018 IPR004087 K Homology domain GO:0003676 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 697 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Gene3D G3DSA:1.10.10.400 253 314 1.6E-23 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF00575 S1 RNA binding domain 624 695 1.3E-18 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Gene3D G3DSA:3.30.230.70 12 252 6.0E-57 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SUPERFAMILY SSF55666 453 554 3.09E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 698 30.528 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF00013 KH domain 562 618 3.2E-8 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Gene3D G3DSA:3.30.1370.10 555 622 4.2E-13 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SUPERFAMILY SSF54211 5 144 8.6E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SMART SM00316 625 695 6.2E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 322 1.5E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 Gene3D G3DSA:3.30.230.70 315 554 1.5E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 PIRSF PIRSF005499 2 715 4.1E-295 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A616_RS19765 c430685c77b450682b8cbd56eec69102 715 SUPERFAMILY SSF54211 294 493 8.6E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.2E-110 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 Gene3D G3DSA:3.40.50.10490 5 236 1.9E-101 T 29-03-2018 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 SUPERFAMILY SSF52313 6 228 3.4E-98 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 PRINTS PR00395 Ribosomal protein S2 signature 6 24 7.2E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 PRINTS PR00395 Ribosomal protein S2 signature 87 104 7.2E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 PRINTS PR00395 Ribosomal protein S2 signature 158 175 7.2E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 PRINTS PR00395 Ribosomal protein S2 signature 175 186 7.2E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 PRINTS PR00395 Ribosomal protein S2 signature 196 210 7.2E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 PRINTS PR00395 Ribosomal protein S2 signature 37 46 7.2E-42 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.345 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A616_RS19875 f6613535109f79d2e2a54da8fa24c967 236 Pfam PF00318 Ribosomal protein S2 9 224 5.0E-100 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS31595 ec02e40d1115f6d1fc7855a04e91338d 185 PIRSF PIRSF006707 5 185 1.1E-39 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type A616_RS31595 ec02e40d1115f6d1fc7855a04e91338d 185 SUPERFAMILY SSF46785 19 169 2.06E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31595 ec02e40d1115f6d1fc7855a04e91338d 185 Gene3D G3DSA:1.10.10.10 16 101 4.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05345 203725b4934b68eda84cdf8add3831f5 65 Gene3D G3DSA:1.20.1640.10 1 64 3.8E-4 T 29-03-2018 A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 Gene3D G3DSA:3.40.50.980 28 193 4.6E-43 T 29-03-2018 A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 Pfam PF00501 AMP-binding enzyme 34 436 1.3E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 SUPERFAMILY SSF56801 11 530 6.54E-153 T 29-03-2018 A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 Gene3D G3DSA:2.30.38.10 345 430 9.6E-28 T 29-03-2018 A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 2.2E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 Gene3D G3DSA:3.30.300.30 431 534 1.3E-27 T 29-03-2018 A616_RS15525 5dd0bac22f5e10618298822f6719b2a0 534 Gene3D G3DSA:3.40.50.980 194 344 4.5E-41 T 29-03-2018 A616_RS20715 c88e0bc6e6564b713000bc152d9afa04 186 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 7 179 8.3E-51 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 A616_RS20715 c88e0bc6e6564b713000bc152d9afa04 186 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 177 1.4E-56 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 A616_RS29655 e01643d117be2994d0c73b77db84bda3 453 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 17 433 1.7E-111 T 29-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A616_RS29655 e01643d117be2994d0c73b77db84bda3 453 Pfam PF02397 Bacterial sugar transferase 247 428 2.7E-68 T 29-03-2018 IPR003362 Bacterial sugar transferase A616_RS29655 e01643d117be2994d0c73b77db84bda3 453 Gene3D G3DSA:3.40.50.720 137 233 9.2E-5 T 29-03-2018 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 Gene3D G3DSA:3.90.780.10 352 577 6.1E-35 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 Gene3D G3DSA:3.60.21.10 27 351 2.4E-67 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 PRINTS PR01607 Apyrase family signature 213 230 4.8E-13 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 PRINTS PR01607 Apyrase family signature 240 263 4.8E-13 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 PRINTS PR01607 Apyrase family signature 267 287 4.8E-13 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 PRINTS PR01607 Apyrase family signature 36 54 4.8E-13 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 PRINTS PR01607 Apyrase family signature 489 508 4.8E-13 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 Pfam PF00149 Calcineurin-like phosphoesterase 39 257 2.6E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 SUPERFAMILY SSF55816 356 568 3.27E-28 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 Pfam PF02872 5'-nucleotidase, C-terminal domain 356 506 1.3E-24 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS31045 a227032ca77a763ff50b6c1a94690b46 662 SUPERFAMILY SSF56300 30 342 1.39E-75 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS09285 86251b5029bb44b71a42437231e62a90 260 Gene3D G3DSA:3.40.50.720 2 259 7.6E-58 T 29-03-2018 A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 2.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 258 1.3E-45 T 29-03-2018 A616_RS09285 86251b5029bb44b71a42437231e62a90 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 1.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS09285 86251b5029bb44b71a42437231e62a90 260 SUPERFAMILY SSF51735 9 258 1.48E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18965 3d8d9169bb9bbef4b88b499748b819c4 280 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 56 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A616_RS18965 3d8d9169bb9bbef4b88b499748b819c4 280 Pfam PF00069 Protein kinase domain 27 274 2.6E-31 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS18965 3d8d9169bb9bbef4b88b499748b819c4 280 Gene3D G3DSA:1.10.510.10 95 262 2.3E-27 T 29-03-2018 A616_RS18965 3d8d9169bb9bbef4b88b499748b819c4 280 SUPERFAMILY SSF56112 11 252 8.61E-46 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS18965 3d8d9169bb9bbef4b88b499748b819c4 280 Gene3D G3DSA:3.30.200.20 6 94 2.9E-17 T 29-03-2018 A616_RS18965 3d8d9169bb9bbef4b88b499748b819c4 280 SMART SM00219 27 262 3.3E-4 T 29-03-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 A616_RS25860 671bbe513d6c63ac5177b4b3af7e657a 283 Gene3D G3DSA:3.60.15.10 12 279 5.4E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS25860 671bbe513d6c63ac5177b4b3af7e657a 283 SMART SM00849 32 267 3.6E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS25860 671bbe513d6c63ac5177b4b3af7e657a 283 SUPERFAMILY SSF56281 30 273 6.42E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS25860 671bbe513d6c63ac5177b4b3af7e657a 283 Pfam PF00753 Metallo-beta-lactamase superfamily 35 168 8.9E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 SUPERFAMILY SSF48498 88 191 6.07E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 Gene3D G3DSA:1.10.357.10 64 196 1.4E-14 T 29-03-2018 A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 Gene3D G3DSA:1.10.10.60 4 63 1.2E-17 T 29-03-2018 A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS07620 ae408a1fdc7aefae22b8f361f09abf0e 196 SUPERFAMILY SSF46689 6 73 1.39E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15000 7d057f36b0b7c300c578d8148099c57b 159 Pfam PF04073 Aminoacyl-tRNA editing domain 35 146 1.6E-20 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS15000 7d057f36b0b7c300c578d8148099c57b 159 Gene3D G3DSA:3.90.960.10 1 159 1.2E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS15000 7d057f36b0b7c300c578d8148099c57b 159 SUPERFAMILY SSF55826 6 156 2.22E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A616_RS15000 7d057f36b0b7c300c578d8148099c57b 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 1.2E-57 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A616_RS15000 7d057f36b0b7c300c578d8148099c57b 159 PIRSF PIRSF006181 1 158 1.1E-60 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 378 4.4E-114 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 SUPERFAMILY SSF55979 255 378 1.15E-30 T 29-03-2018 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 SUPERFAMILY SSF55979 133 252 2.3E-23 T 29-03-2018 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 SUPERFAMILY SSF55979 1 127 6.68E-26 T 29-03-2018 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 252 7.4E-30 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 255 377 1.5E-31 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 SMART SM00480 17 374 4.2E-146 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 Gene3D G3DSA:3.10.150.10 1 129 4.8E-33 T 29-03-2018 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 PIRSF PIRSF000804 1 379 1.1E-115 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 8.7E-36 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 Gene3D G3DSA:3.10.150.10 130 257 2.8E-28 T 29-03-2018 A616_RS00010 789b148ddae17e8fa61c7d23d2826a86 379 Gene3D G3DSA:3.10.150.10 258 379 2.3E-24 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 ProSitePatterns PS00455 Putative AMP-binding domain signature. 674 685 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF53335 1010 1108 5.28E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF56801 504 986 9.85E-138 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF56801 1140 1224 9.85E-138 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:3.40.50.980 680 836 3.3E-38 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:3.40.50.980 530 679 4.2E-42 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:3.40.50.1820 1305 1620 7.7E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Pfam PF00550 Phosphopantetheine attachment site 1213 1285 3.8E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Pfam PF00668 Condensation domain 111 497 1.9E-35 T 29-03-2018 IPR001242 Condensation domain A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF52777 259 501 8.0E-39 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:2.30.38.10 844 923 1.8E-19 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF47336 1207 1285 3.4E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF53474 1493 1616 2.73E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF53474 1306 1453 2.73E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 558 955 2.0E-125 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Pfam PF00501 AMP-binding enzyme 540 933 1.1E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:3.30.300.30 928 1217 4.8E-31 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:3.30.559.10 59 276 6.8E-20 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Gene3D G3DSA:1.10.1200.10 1218 1297 1.0E-14 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SMART SM00823 Phosphopantetheine attachment site 1211 1289 5.0E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1235 1250 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 SUPERFAMILY SSF52777 77 269 4.0E-22 T 29-03-2018 A616_RS24420 fc0133b975fb09c857e30171aa47c625 1623 Pfam PF00975 Thioesterase domain 1325 1432 2.6E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A616_RS11485 9eafdfc7052315c9b6412faf811b4138 252 SUPERFAMILY SSF88697 1 68 3.64E-15 T 29-03-2018 IPR015947 PUA-like domain A616_RS11485 9eafdfc7052315c9b6412faf811b4138 252 Pfam PF04452 RNA methyltransferase 17 239 5.4E-74 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS11485 9eafdfc7052315c9b6412faf811b4138 252 PIRSF PIRSF015601 1 245 1.4E-69 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS11485 9eafdfc7052315c9b6412faf811b4138 252 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 5 243 1.2E-65 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS11485 9eafdfc7052315c9b6412faf811b4138 252 Gene3D G3DSA:3.40.1280.10 1 251 6.1E-84 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS11485 9eafdfc7052315c9b6412faf811b4138 252 SUPERFAMILY SSF75217 71 243 3.53E-54 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS28350 f2418b7653defdad9b51b57a6a7b4089 546 PIRSF PIRSF002741 7 546 1.2E-118 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS28350 f2418b7653defdad9b51b57a6a7b4089 546 Gene3D G3DSA:3.10.105.10 315 514 4.4E-56 T 29-03-2018 A616_RS28350 f2418b7653defdad9b51b57a6a7b4089 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 454 2.0E-92 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS28350 f2418b7653defdad9b51b57a6a7b4089 546 Gene3D G3DSA:3.90.76.10 85 173 3.1E-29 T 29-03-2018 A616_RS28350 f2418b7653defdad9b51b57a6a7b4089 546 SUPERFAMILY SSF53850 48 544 4.69E-139 T 29-03-2018 A616_RS28350 f2418b7653defdad9b51b57a6a7b4089 546 Gene3D G3DSA:3.40.190.10 174 314 1.1E-37 T 29-03-2018 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 SMART SM01016 1 88 1.1E-19 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Gene3D G3DSA:3.30.1360.70 1 112 9.7E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 571 1.2E-150 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Pfam PF00750 tRNA synthetases class I (R) 100 440 5.5E-98 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 SUPERFAMILY SSF52374 112 448 1.94E-102 T 29-03-2018 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 88 2.5E-14 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 SUPERFAMILY SSF55190 1 109 2.09E-20 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 133 9.7E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 133 149 9.7E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 157 170 9.7E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 PRINTS PR01038 Arginyl-tRNA synthetase signature 301 322 9.7E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Gene3D G3DSA:3.40.50.620 113 434 3.9E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 SUPERFAMILY SSF47323 450 571 1.64E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Gene3D G3DSA:1.10.730.10 435 571 7.2E-45 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Pfam PF05746 DALR anticodon binding domain 454 571 1.5E-33 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 571 25.945 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A616_RS12395 16cd9462c768a46454cd3f5157d64cae 571 SMART SM00836 454 571 4.1E-42 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 SUPERFAMILY SSF52540 430 569 5.42E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 SUPERFAMILY SSF52540 11 206 5.42E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 SMART SM00382 631 920 3.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Gene3D G3DSA:3.40.50.300 8 37 0.012 T 29-03-2018 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Gene3D G3DSA:3.30.190.20 141 247 1.9E-46 T 29-03-2018 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 SUPERFAMILY SSF52540 612 911 7.17E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 923 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Gene3D G3DSA:3.40.50.300 619 951 2.2E-56 T 29-03-2018 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Gene3D G3DSA:3.40.50.300 38 140 0.0014 T 29-03-2018 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.28 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Gene3D G3DSA:3.40.50.300 409 618 6.1E-24 T 29-03-2018 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Gene3D G3DSA:1.10.8.280 284 405 1.1E-37 T 29-03-2018 A616_RS29260 0f3b44968e6e716351bdc5229d53c12d 955 Pfam PF00005 ABC transporter 622 858 8.6E-11 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 SUPERFAMILY SSF55874 440 602 5.89E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 Gene3D G3DSA:1.10.287.130 390 446 1.2E-13 T 29-03-2018 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 Pfam PF00672 HAMP domain 318 366 1.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 SMART SM00388 385 450 9.2E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 SUPERFAMILY SSF47384 370 450 3.53E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 SMART SM00304 318 370 5.5E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 386 450 2.5E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 545 5.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 559 5.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 5.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 Gene3D G3DSA:3.30.565.10 454 606 6.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 Gene3D G3DSA:3.30.450.20 325 389 2.7E-4 T 29-03-2018 A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 496 603 5.3E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 SMART SM00387 494 605 2.6E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16160 db728d1239367c0005f4ec35ea002e69 606 SUPERFAMILY SSF158472 318 366 6.15E-8 T 29-03-2018 A616_RS27810 2674011dd025c9828243f9953fa029c8 275 SUPERFAMILY SSF161098 8 268 5.23E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS27810 2674011dd025c9828243f9953fa029c8 275 Gene3D G3DSA:1.10.3720.10 9 270 8.2E-35 T 29-03-2018 A616_RS27810 2674011dd025c9828243f9953fa029c8 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 264 3.0E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS29455 5381251114fce23eb9b669955044e311 492 Pfam PF07196 Flagellin hook IN motif 130 179 4.7E-7 T 29-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A616_RS29455 5381251114fce23eb9b669955044e311 492 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 105 2.3E-24 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 A616_RS29455 5381251114fce23eb9b669955044e311 492 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 209 479 2.1E-46 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 A616_RS06275 dd1b9bd5114f1b98dd9e3b39a8fc73dc 118 Gene3D G3DSA:3.30.2120.10 1 118 4.1E-20 T 29-03-2018 A616_RS28305 17b717c3526866937320cd32eec9210f 543 PIRSF PIRSF002741 1 543 9.3E-119 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS28305 17b717c3526866937320cd32eec9210f 543 SUPERFAMILY SSF53850 42 539 1.28E-130 T 29-03-2018 A616_RS28305 17b717c3526866937320cd32eec9210f 543 Gene3D G3DSA:3.10.105.10 314 514 9.4E-54 T 29-03-2018 A616_RS28305 17b717c3526866937320cd32eec9210f 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 463 8.0E-87 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS28305 17b717c3526866937320cd32eec9210f 543 Gene3D G3DSA:3.40.190.10 215 313 1.3E-22 T 29-03-2018 A616_RS28305 17b717c3526866937320cd32eec9210f 543 Gene3D G3DSA:3.90.76.10 55 214 1.3E-38 T 29-03-2018 A616_RS03275 a595ee0adb8028f12768939c698450c1 276 SUPERFAMILY SSF161098 68 256 1.44E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS03275 a595ee0adb8028f12768939c698450c1 276 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 6 50 2.6E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS03275 a595ee0adb8028f12768939c698450c1 276 Gene3D G3DSA:1.10.3720.10 2 264 7.1E-47 T 29-03-2018 A616_RS03275 a595ee0adb8028f12768939c698450c1 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 276 1.4E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS18270 9d24522f3c6bbdd88f8c9077b0266093 324 Pfam PF01758 Sodium Bile acid symporter family 44 218 1.9E-18 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 104 3.2E-12 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 SMART SM00967 33 108 1.9E-14 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 Pfam PF00588 SpoU rRNA Methylase family 125 264 6.8E-35 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 SUPERFAMILY SSF55315 5 104 4.24E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 SUPERFAMILY SSF75217 120 270 2.03E-41 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 Gene3D G3DSA:3.30.1330.30 1 103 6.8E-25 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS09570 7751ae0643d90cea971b93edc2935adf 275 Gene3D G3DSA:3.40.1280.10 104 275 1.3E-45 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS12495 d68fb6e79955ddadffed92f4e7fca854 382 Gene3D G3DSA:1.20.1250.20 194 378 1.4E-16 T 29-03-2018 A616_RS12495 d68fb6e79955ddadffed92f4e7fca854 382 Pfam PF07690 Major Facilitator Superfamily 5 333 6.8E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS12495 d68fb6e79955ddadffed92f4e7fca854 382 SUPERFAMILY SSF103473 3 377 1.7E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS12495 d68fb6e79955ddadffed92f4e7fca854 382 Gene3D G3DSA:1.20.1250.20 2 187 2.8E-24 T 29-03-2018 A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 SUPERFAMILY SSF56281 51 258 1.49E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 Pfam PF00753 Metallo-beta-lactamase superfamily 77 244 2.5E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 Gene3D G3DSA:3.60.15.10 40 270 9.7E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 ProSitePatterns PS00744 Beta-lactamases class B signature 2. 193 205 - T 29-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 SMART SM00849 73 244 3.9E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 PIRSF PIRSF500176 212 246 140.0 T 29-03-2018 A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 PIRSF PIRSF500176 16 133 2.9E-4 T 29-03-2018 A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 PIRSF PIRSF500176 118 178 69.0 T 29-03-2018 A616_RS07125 c48f61da0b27ef19d31927e525eaf167 278 PIRSF PIRSF001220 18 144 2.3E-5 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS12210 a0528b1853fbd1c523edbe768a100e9c 239 Gene3D G3DSA:3.40.50.150 21 226 1.8E-9 T 29-03-2018 A616_RS12210 a0528b1853fbd1c523edbe768a100e9c 239 SUPERFAMILY SSF53335 41 195 9.1E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS05225 008dc8e35de13b6b272faee9bf8e1a94 327 Gene3D G3DSA:3.40.190.10 35 152 2.0E-24 T 29-03-2018 A616_RS05225 008dc8e35de13b6b272faee9bf8e1a94 327 Gene3D G3DSA:3.40.190.10 153 327 1.8E-43 T 29-03-2018 A616_RS05225 008dc8e35de13b6b272faee9bf8e1a94 327 SUPERFAMILY SSF53850 38 326 1.15E-84 T 29-03-2018 A616_RS05225 008dc8e35de13b6b272faee9bf8e1a94 327 Pfam PF16868 NMT1-like family 43 325 1.1E-94 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A616_RS05225 008dc8e35de13b6b272faee9bf8e1a94 327 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 325 2.5E-110 T 29-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A616_RS18530 e85ee8a0d84cb3b50d87c6f192e7330d 387 Pfam PF00155 Aminotransferase class I and II 44 380 3.5E-46 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS18530 e85ee8a0d84cb3b50d87c6f192e7330d 387 Gene3D G3DSA:3.90.1150.10 282 387 6.7E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS18530 e85ee8a0d84cb3b50d87c6f192e7330d 387 Gene3D G3DSA:3.40.640.10 71 281 5.1E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS18530 e85ee8a0d84cb3b50d87c6f192e7330d 387 SUPERFAMILY SSF53383 24 384 4.4E-78 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 455 9.3E-76 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 SUPERFAMILY SSF50475 2 315 3.92E-86 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 Gene3D G3DSA:3.40.1670.10 316 465 3.4E-35 T 29-03-2018 A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 433 1.4E-113 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 SUPERFAMILY SSF143968 486 598 1.44E-7 T 29-03-2018 A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 Gene3D G3DSA:3.40.1670.10 466 569 3.8E-17 T 29-03-2018 A616_RS18365 29cbb8d4a556ca7680a9b5243d44f98f 609 SUPERFAMILY SSF143968 316 471 3.01E-25 T 29-03-2018 A616_RS20990 1d69526fa4b6c128400020d7a761d86f 212 Pfam PF00156 Phosphoribosyl transferase domain 50 155 3.9E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS20990 1d69526fa4b6c128400020d7a761d86f 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 180 4.3E-44 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS20990 1d69526fa4b6c128400020d7a761d86f 212 Gene3D G3DSA:3.40.50.2020 2 211 6.2E-43 T 29-03-2018 A616_RS20990 1d69526fa4b6c128400020d7a761d86f 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 29.902 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A616_RS20990 1d69526fa4b6c128400020d7a761d86f 212 SUPERFAMILY SSF53271 14 208 8.39E-56 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS12475 31f749ebf75a903fe09544386d16f930 305 Pfam PF03069 Acetamidase/Formamidase family 159 225 4.7E-16 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A616_RS12475 31f749ebf75a903fe09544386d16f930 305 Pfam PF03069 Acetamidase/Formamidase family 50 148 3.3E-10 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A616_RS12475 31f749ebf75a903fe09544386d16f930 305 SUPERFAMILY SSF141130 10 300 1.29E-76 T 29-03-2018 A616_RS12475 31f749ebf75a903fe09544386d16f930 305 Gene3D G3DSA:2.60.120.580 3 115 2.1E-17 T 29-03-2018 A616_RS12475 31f749ebf75a903fe09544386d16f930 305 Gene3D G3DSA:2.60.120.580 127 220 1.3E-27 T 29-03-2018 A616_RS12475 31f749ebf75a903fe09544386d16f930 305 Gene3D G3DSA:3.10.28.20 223 301 1.6E-18 T 29-03-2018 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 Gene3D G3DSA:1.10.10.60 5 40 2.0E-4 T 29-03-2018 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 21 78 1.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 SMART SM00530 21 78 9.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 Gene3D G3DSA:1.25.40.10 122 299 8.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 Gene3D G3DSA:3.30.1190.10 41 84 0.0052 T 29-03-2018 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 SUPERFAMILY SSF47413 20 80 3.03E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS16990 7578ad1efabdf9edcacfd0961d237ef3 448 Gene3D G3DSA:1.25.40.10 303 415 5.9E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 SUPERFAMILY SSF53850 88 294 1.3E-48 T 29-03-2018 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.7E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 Gene3D G3DSA:3.40.190.10 87 175 1.8E-22 T 29-03-2018 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 Pfam PF03466 LysR substrate binding domain 87 291 2.6E-51 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 Gene3D G3DSA:3.40.190.10 176 260 2.9E-25 T 29-03-2018 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 SUPERFAMILY SSF46785 4 110 8.57E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 Gene3D G3DSA:1.10.10.10 2 82 9.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS30790 2c76042cccfb5297fa3e8d180689e2c1 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 SMART SM00257 170 213 3.6E-12 T 29-03-2018 IPR018392 LysM domain A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 SUPERFAMILY SSF51261 251 382 4.6E-33 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 SUPERFAMILY SSF54106 170 213 5.75E-11 T 29-03-2018 IPR018392 LysM domain A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Pfam PF01476 LysM domain 171 213 2.6E-12 T 29-03-2018 IPR018392 LysM domain A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Gene3D G3DSA:3.10.350.10 166 218 3.6E-14 T 29-03-2018 A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Pfam PF07833 Copper amine oxidase N-terminal domain 60 152 2.0E-30 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 SUPERFAMILY SSF55383 63 146 4.38E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Pfam PF01551 Peptidase family M23 272 378 1.9E-24 T 29-03-2018 IPR016047 Peptidase M23 A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Gene3D G3DSA:2.70.70.10 234 393 4.1E-33 T 29-03-2018 A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Gene3D G3DSA:3.30.457.10 72 142 6.8E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS19675 3b5c5bb17a18603cee3fd6c9af4402a6 394 Gene3D G3DSA:3.30.457.10 32 71 1.1E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 SUPERFAMILY SSF55031 210 391 9.84E-44 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 Gene3D G3DSA:3.40.630.10 6 194 4.6E-26 T 29-03-2018 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 Gene3D G3DSA:3.30.70.360 296 382 1.3E-24 T 29-03-2018 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 473 7.2E-160 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 Gene3D G3DSA:3.30.70.360 214 295 3.5E-9 T 29-03-2018 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 117 156 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 Pfam PF01546 Peptidase family M20/M25/M40 85 474 1.5E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 SUPERFAMILY SSF53187 5 187 1.56E-64 T 29-03-2018 A616_RS24040 f9cbe4fb2f717ab4f04b5445d8b23fdb 478 SUPERFAMILY SSF53187 395 477 1.56E-64 T 29-03-2018 A616_RS11620 3f9b82a0181de0c2773a4359444e18a3 98 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 15 91 5.3E-31 T 29-03-2018 IPR022477 Sporulation protein YqfC A616_RS11620 3f9b82a0181de0c2773a4359444e18a3 98 Pfam PF07873 YabP family 27 90 1.5E-17 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 66 79 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 Gene3D G3DSA:3.30.230.40 7 93 1.3E-30 T 29-03-2018 A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 Gene3D G3DSA:3.30.230.40 95 199 4.1E-32 T 29-03-2018 A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 SUPERFAMILY SSF54211 7 91 1.39E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 7 199 42.113 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 37 179 4.9E-63 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A616_RS29220 386b97fefc83da3953fc40c7234d8eae 199 SUPERFAMILY SSF54211 92 184 1.77E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS30425 febdf46a566011ae1c799c91cefc1231 280 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS30425 febdf46a566011ae1c799c91cefc1231 280 SUPERFAMILY SSF52540 5 223 8.5E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30425 febdf46a566011ae1c799c91cefc1231 280 SMART SM00382 33 218 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30425 febdf46a566011ae1c799c91cefc1231 280 Gene3D G3DSA:3.40.50.300 2 231 3.0E-56 T 29-03-2018 A616_RS30425 febdf46a566011ae1c799c91cefc1231 280 Pfam PF00005 ABC transporter 24 162 6.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS13910 3e9c0bc68d8754f95f58bcfec2fed28c 285 PIRSF PIRSF006483 1 279 3.6E-92 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS13910 3e9c0bc68d8754f95f58bcfec2fed28c 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 212 7.8E-63 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS13910 3e9c0bc68d8754f95f58bcfec2fed28c 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 217 271 3.6E-26 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 SUPERFAMILY SSF52540 183 432 1.49E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 441 5.9E-189 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 SUPERFAMILY SSF48024 8 119 4.71E-39 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 Pfam PF03796 DnaB-like helicase C terminal domain 185 439 5.0E-118 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 SMART SM00382 202 390 6.9E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 Gene3D G3DSA:1.10.860.10 4 151 1.6E-50 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 2.4E-37 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A616_RS32155 8c436f93506ca542366389da2f7bf24b 449 Gene3D G3DSA:3.40.50.300 167 448 9.4E-79 T 29-03-2018 A616_RS21825 dd09f9163b9d12b438e1e167c2755a36 192 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 98 1.0E-7 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A616_RS21825 dd09f9163b9d12b438e1e167c2755a36 192 SUPERFAMILY SSF50475 7 128 1.8E-10 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS21825 dd09f9163b9d12b438e1e167c2755a36 192 Gene3D G3DSA:2.30.110.10 1 134 3.0E-17 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS23020 8a94fb6f74cdcceaad1784fe0e4dc014 370 SUPERFAMILY SSF144052 1 359 4.58E-112 T 29-03-2018 A616_RS23020 8a94fb6f74cdcceaad1784fe0e4dc014 370 Pfam PF02073 Thermophilic metalloprotease (M29) 3 332 7.4E-59 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS23020 8a94fb6f74cdcceaad1784fe0e4dc014 370 Gene3D G3DSA:3.40.1830.10 2 164 9.1E-44 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 SUPERFAMILY SSF50156 149 208 9.73E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 4 428 1.7E-162 T 29-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 SMART SM00228 122 198 2.9E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 Pfam PF05580 SpoIVB peptidase S55 215 423 3.1E-89 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 Pfam PF13180 PDZ domain 132 205 8.5E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 Gene3D G3DSA:2.30.42.10 125 229 6.6E-15 T 29-03-2018 A616_RS13175 0d0504bacca81dcf95210bfe7bedb394 444 SUPERFAMILY SSF50494 352 420 1.52E-5 T 29-03-2018 IPR009003 Peptidase S1, PA clan A616_RS16380 372761d129a414da1491f13afd2e9334 99 SMART SM00347 24 96 0.003 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS16380 372761d129a414da1491f13afd2e9334 99 Gene3D G3DSA:1.10.10.10 1 96 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16380 372761d129a414da1491f13afd2e9334 99 SUPERFAMILY SSF46785 5 95 2.83E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16380 372761d129a414da1491f13afd2e9334 99 Pfam PF01047 MarR family 31 88 4.0E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 SUPERFAMILY SSF52540 305 710 5.84E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 Pfam PF12705 PD-(D/E)XK nuclease superfamily 777 1118 2.1E-59 T 29-03-2018 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1146 0.0 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1149 53.209 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 Gene3D G3DSA:3.40.50.300 257 687 2.4E-30 T 29-03-2018 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 Gene3D G3DSA:3.40.50.300 1 143 1.1E-30 T 29-03-2018 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 Gene3D G3DSA:3.40.50.300 144 256 2.2E-30 T 29-03-2018 A616_RS27370 b912b3652d6065ec01264e5239045f7b 1165 Pfam PF13361 UvrD-like helicase C-terminal domain 302 657 8.3E-8 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 SUPERFAMILY SSF50331 254 352 1.19E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 Pfam PF00005 ABC transporter 19 161 3.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 SUPERFAMILY SSF52540 3 240 4.62E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 SMART SM00382 28 211 1.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 Gene3D G3DSA:3.40.50.300 1 251 2.4E-68 T 29-03-2018 A616_RS31115 9e3a887dfec80c73c837f0d15e3606bc 353 Pfam PF08402 TOBE domain 278 351 4.1E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 SUPERFAMILY SSF55874 265 422 3.27E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.2E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 Pfam PF07694 5TMR of 5TMR-LYT 34 145 1.7E-9 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 272 3.7E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 Gene3D G3DSA:1.10.287.130 199 271 1.4E-13 T 29-03-2018 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 SMART SM00387 316 422 1.8E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 SUPERFAMILY SSF47384 201 274 3.92E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 SMART SM00388 211 275 1.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 Gene3D G3DSA:3.30.565.10 275 432 4.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24070 577ae04eadf2a037f37eb99210954d27 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 419 6.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 SMART SM01005 250 378 1.8E-56 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 SUPERFAMILY SSF51419 12 250 4.65E-64 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 267 282 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 305 322 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 208 235 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 130 142 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 67 85 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 360 373 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 284 299 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 165 176 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 PRINTS PR00992 Alanine racemase signature 31 47 3.3E-67 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 SUPERFAMILY SSF50621 244 382 3.1E-45 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 Pfam PF01168 Alanine racemase, N-terminal domain 12 235 1.7E-64 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 Hamap MF_01201 Alanine racemase. 5 378 34.252 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 Pfam PF00842 Alanine racemase, C-terminal domain 250 376 1.5E-39 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 Gene3D G3DSA:3.20.20.10 3 233 1.7E-50 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 Gene3D G3DSA:2.40.37.10 234 387 9.8E-53 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS23145 f3d81e4ba51ebdd11e0927c66ab586dd 393 TIGRFAM TIGR00492 alr: alanine racemase 6 378 6.0E-137 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 Gene3D G3DSA:3.40.50.2300 3 130 5.0E-36 T 29-03-2018 A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 SMART SM00448 4 114 3.3E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 SUPERFAMILY SSF52172 1 192 2.34E-42 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 6.7E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 Pfam PF00072 Response regulator receiver domain 6 115 8.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 SMART SM00862 155 231 2.0E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS31715 ad479290c5eab1fa477aabc2a07191b7 233 Gene3D G3DSA:1.10.10.10 131 233 1.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09635 5e8d3343843d3e58a80e181240072f9a 377 Gene3D G3DSA:3.40.50.2000 182 360 8.9E-51 T 29-03-2018 A616_RS09635 5e8d3343843d3e58a80e181240072f9a 377 SUPERFAMILY SSF53756 5 374 1.06E-88 T 29-03-2018 A616_RS09635 5e8d3343843d3e58a80e181240072f9a 377 Gene3D G3DSA:3.40.50.2000 1 181 7.9E-22 T 29-03-2018 A616_RS09635 5e8d3343843d3e58a80e181240072f9a 377 Pfam PF00534 Glycosyl transferases group 1 185 351 2.6E-38 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS09635 5e8d3343843d3e58a80e181240072f9a 377 Pfam PF13439 Glycosyltransferase Family 4 15 173 1.5E-23 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS25295 1c63943f0226e7497445cf78efa74d25 119 SUPERFAMILY SSF46785 4 108 8.71E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25295 1c63943f0226e7497445cf78efa74d25 119 Gene3D G3DSA:1.10.10.10 13 110 3.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25295 1c63943f0226e7497445cf78efa74d25 119 Pfam PF01638 HxlR-like helix-turn-helix 15 102 8.1E-38 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS15570 8c6527bbaa3a6ad31e7d03c192be71f2 479 Gene3D G3DSA:2.60.40.1610 87 236 1.5E-46 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 A616_RS15570 8c6527bbaa3a6ad31e7d03c192be71f2 479 Pfam PF06863 Protein of unknown function (DUF1254) 89 218 1.1E-44 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 A616_RS15570 8c6527bbaa3a6ad31e7d03c192be71f2 479 Pfam PF06742 Protein of unknown function (DUF1214) 350 462 1.1E-34 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 A616_RS15570 8c6527bbaa3a6ad31e7d03c192be71f2 479 Gene3D G3DSA:2.60.120.600 303 479 3.6E-49 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 A616_RS15570 8c6527bbaa3a6ad31e7d03c192be71f2 479 SUPERFAMILY SSF160935 51 477 4.97E-114 T 29-03-2018 A616_RS18335 03246785344f6a3c5441036b049f2b8b 262 Pfam PF14188 Domain of unknown function (DUF4311) 26 238 5.8E-123 T 29-03-2018 IPR020042 Protein of unknown function DUF4311 A616_RS18335 03246785344f6a3c5441036b049f2b8b 262 TIGRFAM TIGR03580 EF_0832: conserved hypothetical protein EF_0832/AHA_3913 4 257 5.1E-134 T 29-03-2018 IPR020042 Protein of unknown function DUF4311 A616_RS21890 65a164fd40e19e5279a0a8e111da3a61 393 Pfam PF03069 Acetamidase/Formamidase family 8 387 5.8E-174 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A616_RS21890 65a164fd40e19e5279a0a8e111da3a61 393 SUPERFAMILY SSF141130 214 387 4.84E-77 T 29-03-2018 A616_RS21890 65a164fd40e19e5279a0a8e111da3a61 393 SUPERFAMILY SSF141130 17 165 4.84E-77 T 29-03-2018 A616_RS21890 65a164fd40e19e5279a0a8e111da3a61 393 Gene3D G3DSA:2.60.120.580 152 282 4.0E-32 T 29-03-2018 A616_RS21890 65a164fd40e19e5279a0a8e111da3a61 393 Gene3D G3DSA:2.60.120.580 6 151 1.6E-29 T 29-03-2018 A616_RS21890 65a164fd40e19e5279a0a8e111da3a61 393 Gene3D G3DSA:3.10.28.20 299 387 1.6E-17 T 29-03-2018 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 SUPERFAMILY SSF143034 2 64 1.01E-22 T 29-03-2018 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.366 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.1E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.1E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.1E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 3.0E-27 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 A616_RS09435 5dc3d051598583fa38c9753f417afe5d 65 Pfam PF01632 Ribosomal protein L35 2 62 1.2E-24 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 Gene3D G3DSA:1.10.287.950 7 81 0.018 T 29-03-2018 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 Gene3D G3DSA:1.10.287.950 82 266 2.1E-44 T 29-03-2018 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 180 209 2.3E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 151 178 2.3E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 74 103 2.3E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 98 278 1.7E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 SUPERFAMILY SSF58104 33 305 4.45E-57 T 29-03-2018 A616_RS23990 ebfc84414d16aab1e7e5272de1c147d3 314 SMART SM00283 49 311 5.2E-42 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS07300 be7c3cdd53510abb9d16d73a4fd32124 179 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 176 4.3E-54 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07300 be7c3cdd53510abb9d16d73a4fd32124 179 PIRSF PIRSF006135 2 179 2.0E-53 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A616_RS07300 be7c3cdd53510abb9d16d73a4fd32124 179 Gene3D G3DSA:3.40.50.300 3 178 1.7E-57 T 29-03-2018 A616_RS07300 be7c3cdd53510abb9d16d73a4fd32124 179 SUPERFAMILY SSF52540 3 178 1.21E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01735 d696b2726c861b5ab1cbff8887748964 122 Pfam PF07875 Coat F domain 19 80 1.1E-14 T 29-03-2018 IPR012851 Spore coat protein CotF-like A616_RS01735 d696b2726c861b5ab1cbff8887748964 122 Gene3D G3DSA:1.20.1260.10 1 76 2.5E-6 T 29-03-2018 IPR012347 Ferritin-related A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 SUPERFAMILY SSF50249 1 65 1.64E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 PIRSF PIRSF002599 1 66 5.4E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.2E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 SMART SM00357 3 66 2.4E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 Gene3D G3DSA:2.40.50.140 1 66 9.9E-31 T 29-03-2018 A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 PRINTS PR00050 Cold shock protein signature 4 19 7.3E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 PRINTS PR00050 Cold shock protein signature 39 57 7.3E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS04885 d06c3fcf949c2c4df55c1c8e12db8ec2 66 PRINTS PR00050 Cold shock protein signature 24 33 7.3E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Gene3D G3DSA:3.40.50.10490 240 459 1.7E-66 T 29-03-2018 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 2.3E-246 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 SUPERFAMILY SSF56235 2 225 1.63E-69 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Pfam PF13522 Glutamine amidotransferase domain 65 191 5.4E-22 T 29-03-2018 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.463 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 SUPERFAMILY SSF53697 245 610 1.3E-107 T 29-03-2018 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Gene3D G3DSA:3.60.20.10 2 239 2.9E-65 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Gene3D G3DSA:3.40.50.10490 460 608 5.1E-45 T 29-03-2018 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Pfam PF01380 SIS domain 468 592 4.8E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS01720 56b9eab4522beb5b5018abc374007c4b 610 Pfam PF01380 SIS domain 291 416 3.0E-31 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS01465 e47ca73e147d7fc4e0cd1eae36e0e36d 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.244 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z A616_RS01465 e47ca73e147d7fc4e0cd1eae36e0e36d 61 SUPERFAMILY SSF57716 3 61 1.57E-22 T 29-03-2018 A616_RS01465 e47ca73e147d7fc4e0cd1eae36e0e36d 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01465 e47ca73e147d7fc4e0cd1eae36e0e36d 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.0E-25 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01465 e47ca73e147d7fc4e0cd1eae36e0e36d 61 Gene3D G3DSA:4.10.830.10 1 61 9.6E-22 T 29-03-2018 A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 209 292 3.7E-34 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 Gene3D G3DSA:3.40.50.620 1 202 2.1E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 SMART SM00893 9 198 4.8E-41 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 Pfam PF01012 Electron transfer flavoprotein domain 9 186 1.8E-42 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 SUPERFAMILY SSF52402 8 203 2.23E-53 T 29-03-2018 A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 Gene3D G3DSA:3.40.50.1220 205 335 1.3E-55 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 PIRSF PIRSF000089 5 333 7.0E-113 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A616_RS10000 219261f3aeff7ba76f13cb1c91c1b34d 340 SUPERFAMILY SSF52467 209 328 1.13E-45 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 Pfam PF08360 QacR-like protein, C-terminal region 67 195 1.0E-23 T 29-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 2.8E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 Gene3D G3DSA:1.10.357.10 71 199 2.7E-15 T 29-03-2018 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 Gene3D G3DSA:1.10.10.60 48 70 8.6E-12 T 29-03-2018 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 SUPERFAMILY SSF48498 81 194 8.9E-30 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 SUPERFAMILY SSF46689 4 76 1.18E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 Gene3D G3DSA:1.10.10.60 3 47 1.1E-15 T 29-03-2018 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27860 47b9f4d3b641d8629a95dfc1bfe39e10 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS03185 13d6f8de43b295cbc2e61ddcfff2aff9 458 Pfam PF00860 Permease family 16 419 9.4E-43 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS03185 13d6f8de43b295cbc2e61ddcfff2aff9 458 PIRSF PIRSF005353 1 458 2.4E-174 T 29-03-2018 IPR026033 Purine permease PbuG-like A616_RS10070 30edd311326f86d8eeadb8a69fbd6d8f 467 Pfam PF00483 Nucleotidyl transferase 4 274 1.4E-32 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS10070 30edd311326f86d8eeadb8a69fbd6d8f 467 Pfam PF01050 Mannose-6-phosphate isomerase 304 448 4.0E-24 T 29-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A616_RS10070 30edd311326f86d8eeadb8a69fbd6d8f 467 SUPERFAMILY SSF53448 2 271 3.32E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10070 30edd311326f86d8eeadb8a69fbd6d8f 467 Gene3D G3DSA:2.60.120.10 330 449 9.6E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS10070 30edd311326f86d8eeadb8a69fbd6d8f 467 SUPERFAMILY SSF51182 196 448 9.17E-35 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS10070 30edd311326f86d8eeadb8a69fbd6d8f 467 Gene3D G3DSA:3.90.550.10 1 329 2.8E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Gene3D G3DSA:3.30.565.10 388 535 4.9E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Gene3D G3DSA:3.30.450.20 174 320 1.5E-5 T 29-03-2018 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 SUPERFAMILY SSF103190 43 173 2.12E-27 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 SUPERFAMILY SSF55874 415 529 1.83E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 1.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 476 1.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 1.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 1.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 SUPERFAMILY SSF55890 328 407 1.44E-11 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 530 4.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 323 371 4.7E-10 T 29-03-2018 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 SMART SM00387 421 532 1.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Gene3D G3DSA:3.30.450.20 41 173 1.7E-18 T 29-03-2018 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Gene3D G3DSA:1.10.287.130 321 378 3.1E-17 T 29-03-2018 A616_RS07050 36fc6cec40914f11bd3c344541b7838f 544 Pfam PF17203 Single cache domain 3 60 175 5.3E-18 T 29-03-2018 IPR033463 Single cache domain 3 A616_RS19805 c4867b5cfff1a7fde14a0758d3b99d6f 99 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 88 2.3E-16 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A616_RS19805 c4867b5cfff1a7fde14a0758d3b99d6f 99 Gene3D G3DSA:3.30.1330.30 2 99 1.3E-20 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS19805 c4867b5cfff1a7fde14a0758d3b99d6f 99 SUPERFAMILY SSF55315 4 97 2.16E-25 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS24205 079c8fbcaaf135640610ab1d1e6f7cb3 556 Pfam PF00350 Dynamin family 60 213 1.1E-24 T 29-03-2018 IPR022812 Dynamin superfamily A616_RS24205 079c8fbcaaf135640610ab1d1e6f7cb3 556 Gene3D G3DSA:3.40.50.300 21 465 2.7E-34 T 29-03-2018 A616_RS24205 079c8fbcaaf135640610ab1d1e6f7cb3 556 SUPERFAMILY SSF52540 46 269 4.36E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.6E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 Gene3D G3DSA:3.40.190.10 173 246 6.5E-5 T 29-03-2018 A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 Pfam PF03466 LysR substrate binding domain 86 280 1.7E-40 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 Gene3D G3DSA:1.10.10.10 1 82 1.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 SUPERFAMILY SSF53850 87 280 1.49E-33 T 29-03-2018 A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 SUPERFAMILY SSF46785 3 100 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25790 61adac6912c8ee23dca44eaa62c299c3 286 Gene3D G3DSA:3.40.190.10 83 172 9.0E-14 T 29-03-2018 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 1.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 1.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 1.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 1.8E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 SUPERFAMILY SSF46785 2 154 3.82E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 Pfam PF01047 MarR family 59 102 3.3E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 SMART SM00347 31 137 4.9E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15200 5ff58be3ab6e2cdecf35dd01b5fab9ad 162 Gene3D G3DSA:1.10.10.10 2 161 4.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03965 f4416a11f5238292db98ac73e1c66640 266 Pfam PF04294 VanW like protein 67 199 3.0E-40 T 29-03-2018 IPR007391 Vancomycin resistance VanW A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 Gene3D G3DSA:1.25.40.10 130 226 1.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 SMART SM00028 42 75 52.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 SMART SM00028 8 41 3.5E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 SMART SM00028 178 211 78.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 SMART SM00028 76 109 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 Pfam PF13432 Tetratricopeptide repeat 12 67 1.2E-8 T 29-03-2018 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 Gene3D G3DSA:1.25.40.10 92 129 1.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 SUPERFAMILY SSF48452 10 212 1.42E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS26355 db0bdb093e9a90419b22dcb3a770876c 289 Gene3D G3DSA:1.25.40.10 6 91 8.4E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS05965 76b683b5f6df74ad87a908f7ae831bef 205 Gene3D G3DSA:1.10.10.10 6 164 5.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05965 76b683b5f6df74ad87a908f7ae831bef 205 SUPERFAMILY SSF46785 6 121 6.97E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05965 76b683b5f6df74ad87a908f7ae831bef 205 Pfam PF12840 Helix-turn-helix domain 15 69 4.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 SUPERFAMILY SSF53187 173 354 6.29E-63 T 29-03-2018 A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 SUPERFAMILY SSF53187 7 82 6.29E-63 T 29-03-2018 A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 Gene3D G3DSA:3.40.630.10 169 357 3.8E-36 T 29-03-2018 A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 PIRSF PIRSF001123 3 358 3.0E-133 T 29-03-2018 IPR008007 Peptidase M42 A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 Pfam PF05343 M42 glutamyl aminopeptidase 47 340 1.6E-101 T 29-03-2018 IPR008007 Peptidase M42 A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 Gene3D G3DSA:2.40.30.40 71 162 2.3E-32 T 29-03-2018 IPR023367 Peptidase M42, domain 2 A616_RS22895 6f9c2a0ac1cc9a8e0fa041db6ebe2290 359 SUPERFAMILY SSF101821 72 181 1.39E-30 T 29-03-2018 A616_RS14660 39542be125544686977a3780f3a9c17b 303 Gene3D G3DSA:1.10.3720.10 23 291 1.7E-48 T 29-03-2018 A616_RS14660 39542be125544686977a3780f3a9c17b 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 71 1.1E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS14660 39542be125544686977a3780f3a9c17b 303 SUPERFAMILY SSF161098 96 283 2.35E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14660 39542be125544686977a3780f3a9c17b 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 302 9.2E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 Gene3D G3DSA:3.40.640.10 34 270 1.9E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 54.211 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 Pfam PF00464 Serine hydroxymethyltransferase 6 381 5.5E-180 T 29-03-2018 A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 SUPERFAMILY SSF53383 2 412 1.37E-183 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 Gene3D G3DSA:3.90.1150.10 271 411 5.8E-62 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A616_RS30000 59be8b951d61780783d9102f3d7c0024 416 PIRSF PIRSF000412 1 415 4.7E-173 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A616_RS27510 61d7632ad08b64a413ab6b49816e2877 257 SUPERFAMILY SSF52096 1 256 2.34E-93 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS27510 61d7632ad08b64a413ab6b49816e2877 257 Gene3D G3DSA:3.90.226.10 5 214 1.3E-76 T 29-03-2018 A616_RS27510 61d7632ad08b64a413ab6b49816e2877 257 Gene3D G3DSA:1.10.12.10 215 257 4.5E-22 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS27510 61d7632ad08b64a413ab6b49816e2877 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 256 2.0E-81 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS27510 61d7632ad08b64a413ab6b49816e2877 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS09280 776b1bb0cf4f157a14d4cb6e3aebc532 489 Gene3D G3DSA:3.20.20.140 57 404 4.0E-39 T 29-03-2018 A616_RS09280 776b1bb0cf4f157a14d4cb6e3aebc532 489 Pfam PF01979 Amidohydrolase family 73 436 2.2E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS09280 776b1bb0cf4f157a14d4cb6e3aebc532 489 SUPERFAMILY SSF51338 13 67 2.19E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09280 776b1bb0cf4f157a14d4cb6e3aebc532 489 SUPERFAMILY SSF51556 74 386 3.14E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS09280 776b1bb0cf4f157a14d4cb6e3aebc532 489 Gene3D G3DSA:2.30.40.10 4 56 4.6E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09280 776b1bb0cf4f157a14d4cb6e3aebc532 489 SUPERFAMILY SSF51338 348 459 1.69E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS22845 6fbedd5cd51eea1c9659882b89254417 292 SUPERFAMILY SSF46689 3 80 5.55E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS22845 6fbedd5cd51eea1c9659882b89254417 292 Gene3D G3DSA:3.40.50.10490 99 284 5.3E-28 T 29-03-2018 A616_RS22845 6fbedd5cd51eea1c9659882b89254417 292 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 77 1.2E-8 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A616_RS22845 6fbedd5cd51eea1c9659882b89254417 292 Gene3D G3DSA:1.10.10.10 2 80 9.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22845 6fbedd5cd51eea1c9659882b89254417 292 SUPERFAMILY SSF53697 113 280 1.13E-24 T 29-03-2018 A616_RS22845 6fbedd5cd51eea1c9659882b89254417 292 Pfam PF01380 SIS domain 134 258 5.6E-19 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 SMART SM00116 10 57 2.2E-13 T 29-03-2018 IPR000644 CBS domain A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 SMART SM00116 81 128 7.1E-10 T 29-03-2018 IPR000644 CBS domain A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 Gene3D G3DSA:3.30.70.260 151 200 2.1E-9 T 29-03-2018 A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 Gene3D G3DSA:3.10.580.10 1 150 1.2E-28 T 29-03-2018 A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 SUPERFAMILY SSF55021 139 197 5.99E-8 T 29-03-2018 A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 Pfam PF01842 ACT domain 140 183 7.6E-9 T 29-03-2018 IPR002912 ACT domain A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 SUPERFAMILY SSF54631 1 130 2.27E-33 T 29-03-2018 A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 Pfam PF00571 CBS domain 4 57 3.8E-16 T 29-03-2018 IPR000644 CBS domain A616_RS22965 03e87defae6b89421f6001abe4abfb64 214 Pfam PF00571 CBS domain 74 127 1.9E-11 T 29-03-2018 IPR000644 CBS domain A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 Gene3D G3DSA:1.20.1250.20 212 408 3.6E-16 T 29-03-2018 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 SUPERFAMILY SSF103473 16 406 4.58E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 Gene3D G3DSA:1.20.1250.20 12 211 1.0E-32 T 29-03-2018 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 22 401 4.2E-103 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 PRINTS PR01035 Tetracycline resistance protein signature 117 138 3.7E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 PRINTS PR01035 Tetracycline resistance protein signature 90 114 3.7E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 PRINTS PR01035 Tetracycline resistance protein signature 33 49 3.7E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 PRINTS PR01035 Tetracycline resistance protein signature 177 197 3.7E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 PRINTS PR01035 Tetracycline resistance protein signature 290 311 3.7E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS19480 c5c2cb808c98914379570a09bb034e90 410 Pfam PF07690 Major Facilitator Superfamily 33 369 7.5E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS30550 64363603ccc0fc66a690a95497d9865e 491 Gene3D G3DSA:1.10.287.950 163 246 0.0014 T 29-03-2018 A616_RS30550 64363603ccc0fc66a690a95497d9865e 491 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 286 425 2.3E-32 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS30550 64363603ccc0fc66a690a95497d9865e 491 SMART SM00283 217 478 6.9E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS30550 64363603ccc0fc66a690a95497d9865e 491 SUPERFAMILY SSF58104 181 487 4.45E-58 T 29-03-2018 A616_RS30550 64363603ccc0fc66a690a95497d9865e 491 Gene3D G3DSA:1.10.287.950 247 482 4.0E-48 T 29-03-2018 A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 SUPERFAMILY SSF52540 5 197 8.86E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 449 3.7E-150 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 4 441 46.642 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 Gene3D G3DSA:3.40.50.880 246 458 3.7E-23 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 SUPERFAMILY SSF52317 247 451 3.48E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 193 8.3E-23 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 Gene3D G3DSA:3.40.50.300 1 180 3.4E-38 T 29-03-2018 A616_RS07365 d492bae58a01c73bb15f3cdeb9ef6a6b 458 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 440 2.6E-40 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A616_RS14100 53c600c09e2c73783583971ce15f67cb 168 Pfam PF00583 Acetyltransferase (GNAT) family 51 142 8.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS14100 53c600c09e2c73783583971ce15f67cb 168 SUPERFAMILY SSF55729 1 167 5.66E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS14100 53c600c09e2c73783583971ce15f67cb 168 Gene3D G3DSA:3.40.630.30 1 168 4.2E-28 T 29-03-2018 A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 SUPERFAMILY SSF52540 5 227 1.85E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 SUPERFAMILY SSF52540 254 484 1.64E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 Pfam PF00005 ABC transporter 21 169 2.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 Pfam PF00005 ABC transporter 270 428 1.6E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 SMART SM00382 29 217 2.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 SMART SM00382 279 477 2.5 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 Gene3D G3DSA:3.40.50.300 250 494 1.4E-39 T 29-03-2018 A616_RS30540 6f8850b61bb143212b3e14a908ba7ac6 509 Gene3D G3DSA:3.40.50.300 1 245 5.3E-55 T 29-03-2018 A616_RS02445 efead627929eb6793383116cdad5d210 377 Gene3D G3DSA:3.90.1510.10 42 276 4.4E-92 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 A616_RS02445 efead627929eb6793383116cdad5d210 377 Pfam PF02595 Glycerate kinase family 3 372 1.3E-147 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS02445 efead627929eb6793383116cdad5d210 377 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 374 1.7E-152 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS02445 efead627929eb6793383116cdad5d210 377 PIRSF PIRSF006078 1 377 4.7E-138 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS02445 efead627929eb6793383116cdad5d210 377 SUPERFAMILY SSF110738 1 375 8.5E-135 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A616_RS27060 ba7a4d2924903ad9503af85596fd5ee3 115 Gene3D G3DSA:1.10.10.10 3 114 1.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27060 ba7a4d2924903ad9503af85596fd5ee3 115 SUPERFAMILY SSF46785 7 112 1.79E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27060 ba7a4d2924903ad9503af85596fd5ee3 115 Pfam PF03551 Transcriptional regulator PadR-like family 19 92 3.0E-22 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Pfam PF00571 CBS domain 513 571 1.2E-9 T 29-03-2018 IPR000644 CBS domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Pfam PF00563 EAL domain 180 410 4.6E-52 T 29-03-2018 IPR001633 EAL domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Pfam PF00990 Diguanylate cyclase, GGDEF domain 584 728 1.0E-16 T 29-03-2018 IPR000160 GGDEF domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 576 728 2.2E-16 T 29-03-2018 IPR000160 GGDEF domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Gene3D G3DSA:3.10.580.10 443 571 2.3E-13 T 29-03-2018 A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Gene3D G3DSA:3.30.70.270 572 744 2.5E-24 T 29-03-2018 A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Gene3D G3DSA:3.30.70.270 15 184 4.2E-6 T 29-03-2018 A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 Gene3D G3DSA:3.20.20.450 185 416 9.6E-62 T 29-03-2018 IPR001633 EAL domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 SMART SM00052 173 415 1.8E-34 T 29-03-2018 IPR001633 EAL domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 SUPERFAMILY SSF141868 180 410 9.81E-62 T 29-03-2018 IPR001633 EAL domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 SMART SM00267 569 743 1.0E-10 T 29-03-2018 IPR000160 GGDEF domain A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 SUPERFAMILY SSF54631 452 573 3.28E-12 T 29-03-2018 A616_RS13455 3cb787eb621dc518326cec76fc5b4c0e 757 SUPERFAMILY SSF55073 585 738 2.43E-21 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS05850 280d7ce57bb3817cb08e1463d5c5cc00 181 SUPERFAMILY SSF52218 1 174 5.32E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS05850 280d7ce57bb3817cb08e1463d5c5cc00 181 Gene3D G3DSA:3.40.50.360 1 174 4.6E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS05850 280d7ce57bb3817cb08e1463d5c5cc00 181 Pfam PF03358 NADPH-dependent FMN reductase 1 123 5.2E-19 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A616_RS02040 adc52ccd8638b3e04b725605fd19b9af 335 Gene3D G3DSA:1.10.3470.10 2 335 3.1E-57 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS02040 adc52ccd8638b3e04b725605fd19b9af 335 SUPERFAMILY SSF81345 7 328 1.44E-73 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS02040 adc52ccd8638b3e04b725605fd19b9af 335 Pfam PF01032 FecCD transport family 19 328 8.3E-79 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS25935 1ee2ca12071016a259a1ad47325da8b5 109 SUPERFAMILY SSF51182 1 100 1.35E-13 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS25935 1ee2ca12071016a259a1ad47325da8b5 109 Pfam PF07883 Cupin domain 38 86 1.0E-6 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS25935 1ee2ca12071016a259a1ad47325da8b5 109 Gene3D G3DSA:2.60.120.10 1 100 3.0E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS11925 c8a6cc013e30570d9225f61f43c68b24 1013 Gene3D G3DSA:2.60.40.1190 732 974 3.5E-4 T 29-03-2018 A616_RS11925 c8a6cc013e30570d9225f61f43c68b24 1013 SUPERFAMILY SSF51445 520 695 1.97E-14 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS11925 c8a6cc013e30570d9225f61f43c68b24 1013 SUPERFAMILY SSF51445 329 490 1.97E-14 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS11925 c8a6cc013e30570d9225f61f43c68b24 1013 Gene3D G3DSA:3.20.20.80 349 729 7.8E-25 T 29-03-2018 A616_RS11925 c8a6cc013e30570d9225f61f43c68b24 1013 Gene3D G3DSA:3.20.20.80 40 321 0.0064 T 29-03-2018 A616_RS06790 4b90990020622804218b97b04ad3b2f6 210 SUPERFAMILY SSF53448 5 196 6.05E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS06790 4b90990020622804218b97b04ad3b2f6 210 Gene3D G3DSA:3.90.550.10 1 200 1.6E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS06790 4b90990020622804218b97b04ad3b2f6 210 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 4 198 20.231 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A616_RS06790 4b90990020622804218b97b04ad3b2f6 210 Pfam PF12804 MobA-like NTP transferase domain 8 169 3.3E-30 T 29-03-2018 IPR025877 MobA-like NTP transferase A616_RS30935 479a97255c17532422b1ebf4772496fd 256 Gene3D G3DSA:3.40.50.720 52 256 8.8E-64 T 29-03-2018 A616_RS30935 479a97255c17532422b1ebf4772496fd 256 Gene3D G3DSA:3.40.50.720 1 51 2.0E-12 T 29-03-2018 A616_RS30935 479a97255c17532422b1ebf4772496fd 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS30935 479a97255c17532422b1ebf4772496fd 256 SUPERFAMILY SSF51735 7 254 8.52E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 253 1.8E-71 T 29-03-2018 A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.8E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.8E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.8E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.8E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.8E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS30935 479a97255c17532422b1ebf4772496fd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.8E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS26395 d3f6093154bc9aa272e00ce731503693 377 Gene3D G3DSA:3.90.1150.10 246 377 2.4E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS26395 d3f6093154bc9aa272e00ce731503693 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS26395 d3f6093154bc9aa272e00ce731503693 377 PIRSF PIRSF001434 1 377 2.0E-148 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS26395 d3f6093154bc9aa272e00ce731503693 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 376 1.4E-155 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS26395 d3f6093154bc9aa272e00ce731503693 377 Gene3D G3DSA:3.40.640.10 1 245 2.5E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS26395 d3f6093154bc9aa272e00ce731503693 377 SUPERFAMILY SSF53383 5 376 2.09E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS29865 0688ba323b71a4b1e372ea3385856c60 335 Pfam PF00146 NADH dehydrogenase 21 325 6.8E-127 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29865 0688ba323b71a4b1e372ea3385856c60 335 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 214 227 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29865 0688ba323b71a4b1e372ea3385856c60 335 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 13 331 25.422 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS31195 53f7422b3b027010487ccf1912706a63 317 SUPERFAMILY SSF81345 5 312 1.16E-69 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS31195 53f7422b3b027010487ccf1912706a63 317 Gene3D G3DSA:1.10.3470.10 4 317 5.6E-45 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS31195 53f7422b3b027010487ccf1912706a63 317 Pfam PF01032 FecCD transport family 10 311 2.4E-68 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 Gene3D G3DSA:3.40.50.1100 41 138 5.8E-39 T 29-03-2018 A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 304 5.4E-128 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 7.0E-69 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 304 1.1E-133 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 Gene3D G3DSA:3.40.50.1100 139 304 9.9E-55 T 29-03-2018 A616_RS09960 e69c32543dbf3da4642f8b1b009f80b6 304 SUPERFAMILY SSF53686 2 303 4.98E-98 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS28655 39a7f33f200509ea4270ed374d2a9039 299 SUPERFAMILY SSF54211 26 172 2.28E-14 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS28655 39a7f33f200509ea4270ed374d2a9039 299 Pfam PF00288 GHMP kinases N terminal domain 94 128 9.7E-8 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A616_RS28655 39a7f33f200509ea4270ed374d2a9039 299 PIRSF PIRSF033887 3 299 2.7E-87 T 29-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 A616_RS28655 39a7f33f200509ea4270ed374d2a9039 299 Gene3D G3DSA:3.30.230.10 40 165 2.5E-10 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS18350 521292040f748a83bc5fbe2b523cbeb0 123 Gene3D G3DSA:1.10.1790.10 21 119 1.4E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS18350 521292040f748a83bc5fbe2b523cbeb0 123 SUPERFAMILY SSF63520 27 114 1.18E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 A616_RS05415 6ce950d7db0c6da798be35aa63574dda 261 Gene3D G3DSA:3.40.50.150 7 220 9.2E-19 T 29-03-2018 A616_RS05415 6ce950d7db0c6da798be35aa63574dda 261 SUPERFAMILY SSF53335 48 204 3.72E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS05415 6ce950d7db0c6da798be35aa63574dda 261 Pfam PF13649 Methyltransferase domain 62 146 1.9E-13 T 29-03-2018 A616_RS20000 edb8abbb2dfa8b67c3e51929ff1a0078 272 SUPERFAMILY SSF117143 92 232 1.7E-31 T 29-03-2018 A616_RS20000 edb8abbb2dfa8b67c3e51929ff1a0078 272 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 188 270 1.6E-21 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A616_RS20000 edb8abbb2dfa8b67c3e51929ff1a0078 272 Pfam PF00460 Flagella basal body rod protein 5 35 1.1E-11 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A616_RS20000 edb8abbb2dfa8b67c3e51929ff1a0078 272 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 151 253 9.8E-25 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A616_RS20000 edb8abbb2dfa8b67c3e51929ff1a0078 272 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 140 1.0E-41 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 Gene3D G3DSA:1.20.1250.20 249 496 1.1E-27 T 29-03-2018 A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 Gene3D G3DSA:1.20.1250.20 8 197 9.0E-37 T 29-03-2018 A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 SUPERFAMILY SSF103473 8 190 9.42E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 SUPERFAMILY SSF103473 197 416 2.22E-28 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 SUPERFAMILY SSF103473 464 489 2.22E-28 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 419 1.1E-78 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A616_RS07135 c02fb7b64b03a72d343ca7105c07ac5a 507 Pfam PF07690 Major Facilitator Superfamily 15 406 2.0E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 263 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 SMART SM00342 184 267 5.3E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 Pfam PF01497 Periplasmic binding protein 293 506 1.3E-15 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 SUPERFAMILY SSF46689 168 218 1.08E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 Pfam PF12833 Helix-turn-helix domain 190 268 3.3E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 Gene3D G3DSA:2.60.120.10 16 225 6.3E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 SUPERFAMILY SSF46689 220 269 8.51E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 SUPERFAMILY SSF53807 275 517 1.96E-33 T 29-03-2018 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 Gene3D G3DSA:1.10.10.60 226 276 6.0E-15 T 29-03-2018 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 Gene3D G3DSA:3.40.50.1980 376 530 1.6E-25 T 29-03-2018 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 267 3.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 251 3.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS24655 91b81a111be319cf9a49ad38f6f06a2b 530 Gene3D G3DSA:3.40.50.1980 277 375 3.4E-7 T 29-03-2018 A616_RS09140 3e11b4256e9457e396efe3989169fac5 292 SUPERFAMILY SSF56112 10 264 1.02E-32 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS09140 3e11b4256e9457e396efe3989169fac5 292 Pfam PF01636 Phosphotransferase enzyme family 28 263 2.8E-26 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS09140 3e11b4256e9457e396efe3989169fac5 292 Gene3D G3DSA:3.90.1200.10 49 289 5.4E-25 T 29-03-2018 A616_RS07460 270e802dd9f469616ef0842922dbb714 309 SUPERFAMILY SSF52317 3 159 1.28E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS07460 270e802dd9f469616ef0842922dbb714 309 SUPERFAMILY SSF141986 141 300 1.83E-44 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain A616_RS07460 270e802dd9f469616ef0842922dbb714 309 Gene3D G3DSA:3.50.30.60 153 308 6.4E-45 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain A616_RS07460 270e802dd9f469616ef0842922dbb714 309 Gene3D G3DSA:3.40.50.10740 1 152 2.1E-52 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain A616_RS07460 270e802dd9f469616ef0842922dbb714 309 Pfam PF02016 LD-carboxypeptidase 13 294 4.4E-83 T 29-03-2018 IPR003507 Peptidase family S66 A616_RS07460 270e802dd9f469616ef0842922dbb714 309 PIRSF PIRSF028757 1 308 5.0E-86 T 29-03-2018 IPR003507 Peptidase family S66 A616_RS19795 0deb6ff0ec49f445f674992537280db6 93 Pfam PF04456 Protein of unknown function (DUF503) 4 88 4.3E-31 T 29-03-2018 IPR007546 Protein of unknown function DUF503 A616_RS19795 0deb6ff0ec49f445f674992537280db6 93 Gene3D G3DSA:3.30.70.1120 1 91 3.2E-32 T 29-03-2018 A616_RS19795 0deb6ff0ec49f445f674992537280db6 93 SUPERFAMILY SSF103007 1 92 1.83E-29 T 29-03-2018 IPR007546 Protein of unknown function DUF503 A616_RS32240 a8e7ba5ff77e843a02f80d9b2494f512 237 Pfam PF04474 Protein of unknown function (DUF554) 4 224 5.0E-75 T 29-03-2018 IPR007563 Protein of unknown function DUF554 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 SUPERFAMILY SSF47336 962 1029 2.75E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 SUPERFAMILY SSF52777 14 187 6.89E-32 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 SUPERFAMILY SSF52777 1058 1228 7.78E-28 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:1.10.1200.10 971 1032 7.9E-13 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Pfam PF13193 AMP-binding enzyme C-terminal domain 868 941 1.2E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 PRINTS PR00154 AMP-binding signature 613 621 3.8E-5 T 29-03-2018 IPR020459 AMP-binding A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 PRINTS PR00154 AMP-binding signature 601 612 3.8E-5 T 29-03-2018 IPR020459 AMP-binding A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 488 884 5.0E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Pfam PF00550 Phosphopantetheine attachment site 971 1029 1.6E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:3.40.50.980 460 607 2.0E-43 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 SUPERFAMILY SSF52777 1250 1479 4.45E-31 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 SUPERFAMILY SSF56801 424 980 1.44E-146 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 SUPERFAMILY SSF52777 193 453 2.45E-39 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:2.30.38.10 770 850 1.8E-24 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1356 1498 2.0E-31 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:3.40.50.980 608 760 8.5E-32 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:3.30.300.30 855 970 4.4E-34 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Pfam PF00668 Condensation domain 1051 1491 1.1E-62 T 29-03-2018 IPR001242 Condensation domain A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Pfam PF00668 Condensation domain 11 442 4.6E-90 T 29-03-2018 IPR001242 Condensation domain A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Pfam PF00501 AMP-binding enzyme 467 859 5.4E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:3.30.559.10 6 211 6.9E-22 T 29-03-2018 A616_RS18545 5534b40f0622a37d026ce32aaa7e8dee 1501 Gene3D G3DSA:3.30.559.10 1038 1244 7.4E-25 T 29-03-2018 A616_RS07680 1b37209f21801c44203f67b3393916d5 167 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 90 3.6E-13 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A616_RS07680 1b37209f21801c44203f67b3393916d5 167 Gene3D G3DSA:2.30.110.10 3 167 3.8E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS07680 1b37209f21801c44203f67b3393916d5 167 SUPERFAMILY SSF50475 8 150 4.71E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS07680 1b37209f21801c44203f67b3393916d5 167 PIRSF PIRSF004633 1 167 4.5E-51 T 29-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain A616_RS13660 d15dc4d33289fbf9c762cb9fda48cb23 301 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 9 299 2.0E-95 T 29-03-2018 A616_RS13660 d15dc4d33289fbf9c762cb9fda48cb23 301 Pfam PF14045 YIEGIA protein 14 293 6.5E-125 T 29-03-2018 IPR025918 YIEGIA protein A616_RS01125 a3c077a82322bfc0300d64a558e9e410 547 Gene3D G3DSA:1.20.5.700 1 30 0.0013 T 29-03-2018 A616_RS01125 a3c077a82322bfc0300d64a558e9e410 547 Pfam PF05787 Bacterial protein of unknown function (DUF839) 56 516 5.0E-129 T 29-03-2018 IPR008557 Protein of unknown function DUF839 A616_RS01125 a3c077a82322bfc0300d64a558e9e410 547 Gene3D G3DSA:2.120.10.30 159 539 2.5E-11 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS01125 a3c077a82322bfc0300d64a558e9e410 547 SUPERFAMILY SSF101898 268 514 2.01E-12 T 29-03-2018 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 Gene3D G3DSA:3.30.1490.20 125 190 1.3E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 SUPERFAMILY SSF56059 110 310 2.3E-69 T 29-03-2018 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 Gene3D G3DSA:3.40.50.20 13 98 2.8E-20 T 29-03-2018 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 Pfam PF02222 ATP-grasp domain 119 290 6.7E-64 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 Gene3D G3DSA:3.30.470.20 191 377 5.4E-47 T 29-03-2018 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 SUPERFAMILY SSF51246 314 380 7.85E-15 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 368 3.0E-133 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 366 44.887 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A616_RS03210 cba5057526711b6933e87567ae3d7d1b 387 SUPERFAMILY SSF52440 9 107 7.63E-26 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 PIRSF PIRSF000478 1 434 6.0E-165 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 SUPERFAMILY SSF54680 331 433 3.27E-29 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 Gene3D G3DSA:1.20.970.10 1 66 1.4E-27 T 29-03-2018 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 SUPERFAMILY SSF47648 1 69 1.2E-22 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 Gene3D G3DSA:3.90.1170.30 338 422 4.6E-30 T 29-03-2018 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 SMART SM00941 345 419 3.6E-30 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 418 9.0E-175 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 419 2.6E-24 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 2.0E-23 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 Gene3D G3DSA:3.40.1030.10 68 337 3.5E-91 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 Pfam PF00591 Glycosyl transferase family, a/b domain 78 305 3.5E-46 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13355 7be1b3494ee8a421d119a75a6ab5087f 435 SUPERFAMILY SSF52418 69 327 2.22E-92 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 318 1.2E-32 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 Gene3D G3DSA:3.40.50.720 2 114 3.0E-33 T 29-03-2018 A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 288 3.9E-63 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 SUPERFAMILY SSF51735 102 289 2.08E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 Gene3D G3DSA:3.40.50.720 115 291 5.8E-57 T 29-03-2018 A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 SUPERFAMILY SSF52283 3 136 1.1E-37 T 29-03-2018 A616_RS26415 f03a19f7e0b164f84fda8d76c7ec82bc 319 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 177 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A616_RS08890 d82b485fa74a554d04372e744a081da9 408 Pfam PF02342 TerD domain 1 176 2.2E-55 T 29-03-2018 IPR003325 TerD domain GO:0006950 A616_RS08890 d82b485fa74a554d04372e744a081da9 408 Gene3D G3DSA:2.60.60.30 230 393 4.3E-25 T 29-03-2018 A616_RS08890 d82b485fa74a554d04372e744a081da9 408 Gene3D G3DSA:2.60.60.30 19 175 7.1E-43 T 29-03-2018 A616_RS08890 d82b485fa74a554d04372e744a081da9 408 PIRSF PIRSF037118 2 408 1.2E-131 T 29-03-2018 IPR017115 Tellurite resistance, TerA A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 SMART SM00388 293 360 6.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 SUPERFAMILY SSF55874 349 518 1.96E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 SUPERFAMILY SSF158472 233 284 4.05E-10 T 29-03-2018 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 Pfam PF00512 His Kinase A (phospho-acceptor) domain 293 358 4.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 519 2.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 SMART SM00304 233 285 2.3E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 SMART SM00387 407 520 2.2E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 Gene3D G3DSA:1.10.287.130 276 356 1.1E-13 T 29-03-2018 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 Pfam PF00672 HAMP domain 233 282 8.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 1.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 Gene3D G3DSA:3.30.565.10 365 522 8.4E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS04700 2f20c3e50ac8af6006e827b55041a50b 522 SUPERFAMILY SSF47384 271 359 3.73E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS30395 a78f0afcf1e26aefea4806d8b86bbbe8 573 Gene3D G3DSA:3.50.50.60 2 570 1.1E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS30395 a78f0afcf1e26aefea4806d8b86bbbe8 573 Pfam PF05199 GMC oxidoreductase 436 557 5.6E-17 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A616_RS30395 a78f0afcf1e26aefea4806d8b86bbbe8 573 SUPERFAMILY SSF51905 7 321 2.5E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS30395 a78f0afcf1e26aefea4806d8b86bbbe8 573 SUPERFAMILY SSF51905 505 565 2.5E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS30395 a78f0afcf1e26aefea4806d8b86bbbe8 573 Pfam PF00732 GMC oxidoreductase 142 328 1.7E-8 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 PIRSF PIRSF000726 1 455 4.2E-76 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 9.7E-83 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 Pfam PF00696 Amino acid kinase family 2 277 3.1E-38 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 Gene3D G3DSA:3.30.70.260 283 375 1.9E-18 T 29-03-2018 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 Gene3D G3DSA:3.30.70.260 376 455 1.5E-21 T 29-03-2018 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 SUPERFAMILY SSF55021 297 361 8.39E-9 T 29-03-2018 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 SUPERFAMILY SSF53633 1 290 5.63E-63 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 Pfam PF13840 ACT domain 382 445 1.1E-6 T 29-03-2018 IPR027795 GATS-like ACT domain A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 Gene3D G3DSA:3.40.1160.10 1 282 1.1E-52 T 29-03-2018 A616_RS26665 0f27c8a6eaf207aa54054856bb5d3361 467 SUPERFAMILY SSF55021 374 450 2.98E-20 T 29-03-2018 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 Gene3D G3DSA:1.10.10.10 133 237 9.5E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 175 229 6.3E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 SUPERFAMILY SSF52172 9 132 3.84E-33 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 ProSitePatterns PS00622 LuxR-type HTH domain signature. 190 217 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 SMART SM00448 10 123 6.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 190 4.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 218 4.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 206 4.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 SUPERFAMILY SSF46894 166 236 2.72E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 Pfam PF00072 Response regulator receiver domain 12 123 1.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 SMART SM00421 173 230 4.1E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS04485 02160b69e9f0a1f0bfee56965e6646b7 237 Gene3D G3DSA:3.40.50.2300 2 132 1.6E-33 T 29-03-2018 A616_RS06930 b4fa511d0252ce5851637dd3f9e4b3ce 594 SUPERFAMILY SSF52540 333 453 4.98E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06930 b4fa511d0252ce5851637dd3f9e4b3ce 594 SUPERFAMILY SSF52540 261 295 4.98E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06930 b4fa511d0252ce5851637dd3f9e4b3ce 594 Pfam PF07728 AAA domain (dynein-related subfamily) 308 448 2.5E-14 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A616_RS06930 b4fa511d0252ce5851637dd3f9e4b3ce 594 Gene3D G3DSA:3.40.50.300 197 454 8.1E-23 T 29-03-2018 A616_RS06930 b4fa511d0252ce5851637dd3f9e4b3ce 594 SMART SM00382 267 458 3.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08910 771d4424826e1f95f296c50000dd6d20 343 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 7 336 8.3E-91 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI A616_RS08910 771d4424826e1f95f296c50000dd6d20 343 Pfam PF01594 AI-2E family transporter 6 331 3.8E-55 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like A616_RS24320 76be06638d896ae44c61eeadf6e95831 418 Pfam PF07690 Major Facilitator Superfamily 19 354 1.6E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24320 76be06638d896ae44c61eeadf6e95831 418 SUPERFAMILY SSF103473 19 417 8.37E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS24320 76be06638d896ae44c61eeadf6e95831 418 Gene3D G3DSA:1.20.1250.20 12 210 1.1E-19 T 29-03-2018 A616_RS24320 76be06638d896ae44c61eeadf6e95831 418 Gene3D G3DSA:1.20.1250.20 214 418 8.4E-13 T 29-03-2018 A616_RS03865 644c9a9ab8340709bd13b8d042158b2d 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 359 2.4E-72 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS03865 644c9a9ab8340709bd13b8d042158b2d 363 Pfam PF03845 Spore germination protein 6 323 1.4E-60 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS19365 81cff808c477b6ef434e9e1d2c2a3f49 48 Pfam PF00239 Resolvase, N terminal domain 2 45 3.6E-8 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS19365 81cff808c477b6ef434e9e1d2c2a3f49 48 Gene3D G3DSA:3.40.50.1390 1 48 2.6E-8 T 29-03-2018 A616_RS19365 81cff808c477b6ef434e9e1d2c2a3f49 48 SUPERFAMILY SSF53041 1 46 7.59E-10 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS25345 cfde2a295057900b1df5dbc2b5175110 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 28 139 1.3E-54 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A616_RS25345 cfde2a295057900b1df5dbc2b5175110 165 Gene3D G3DSA:3.30.1130.10 21 165 8.7E-43 T 29-03-2018 A616_RS25345 cfde2a295057900b1df5dbc2b5175110 165 PIRSF PIRSF027377 8 147 4.0E-62 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A616_RS25345 cfde2a295057900b1df5dbc2b5175110 165 Pfam PF14489 QueF-like protein 62 140 1.8E-35 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A616_RS25345 cfde2a295057900b1df5dbc2b5175110 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 71.859 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A616_RS25345 cfde2a295057900b1df5dbc2b5175110 165 SUPERFAMILY SSF55620 25 134 1.56E-27 T 29-03-2018 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Gene3D G3DSA:1.20.120.140 1 92 9.1E-31 T 29-03-2018 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 SMART SM00962 101 296 1.0E-122 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 2.4E-24 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 SMART SM00382 100 247 4.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20250 0397862043db595621ffc6e1192a31f6 470 SUPERFAMILY SSF52540 43 354 3.77E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Gene3D G3DSA:3.40.50.300 232 314 2.0E-11 T 29-03-2018 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 SMART SM00963 2 87 3.8E-36 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 460 35.214 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 9.2E-81 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Pfam PF02978 Signal peptide binding domain 327 424 9.2E-33 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Gene3D G3DSA:1.10.260.30 327 429 7.8E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 SUPERFAMILY SSF47446 327 428 1.8E-34 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 426 5.4E-189 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A616_RS20250 0397862043db595621ffc6e1192a31f6 470 Gene3D G3DSA:3.40.50.300 96 231 9.8E-41 T 29-03-2018 A616_RS25205 1df3ef4cbec8fb542b1bf30647a1647e 238 PIRSF PIRSF039137 1 238 7.6E-106 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 A616_RS25205 1df3ef4cbec8fb542b1bf30647a1647e 238 SMART SM00382 29 217 9.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25205 1df3ef4cbec8fb542b1bf30647a1647e 238 Pfam PF00005 ABC transporter 20 166 2.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25205 1df3ef4cbec8fb542b1bf30647a1647e 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25205 1df3ef4cbec8fb542b1bf30647a1647e 238 SUPERFAMILY SSF52540 3 235 6.91E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25205 1df3ef4cbec8fb542b1bf30647a1647e 238 Gene3D G3DSA:3.40.50.300 1 236 1.1E-53 T 29-03-2018 A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 241 398 1.1E-38 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 Gene3D G3DSA:1.10.3090.10 140 401 5.4E-44 T 29-03-2018 A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 167 226 3.5E-17 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 SUPERFAMILY SSF81891 138 400 3.14E-46 T 29-03-2018 A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 Gene3D G3DSA:3.30.460.10 3 139 2.7E-46 T 29-03-2018 A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 SUPERFAMILY SSF81301 4 135 1.06E-41 T 29-03-2018 A616_RS13940 22e7d9354cd1d86df0f2aeeca0ecfbe1 407 Pfam PF01743 Poly A polymerase head domain 20 140 2.0E-32 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A616_RS06480 e9e2ce384d7b4b0cae4f88987c2c5c37 174 Pfam PF06114 IrrE N-terminal-like domain 48 166 6.5E-20 T 29-03-2018 IPR010359 IrrE N-terminal-like domain A616_RS13700 4b3c8e8dd10e03d384099c1e575f9b53 98 SUPERFAMILY SSF54292 11 95 3.37E-19 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS13700 4b3c8e8dd10e03d384099c1e575f9b53 98 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 85 3.6E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS13700 4b3c8e8dd10e03d384099c1e575f9b53 98 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A616_RS13700 4b3c8e8dd10e03d384099c1e575f9b53 98 Gene3D G3DSA:3.10.20.30 1 97 4.3E-19 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 PIRSF PIRSF001413 1 388 1.3E-149 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 386 46.603 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 Gene3D G3DSA:3.40.50.1100 12 206 3.8E-42 T 29-03-2018 A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 10 384 1.9E-171 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 SUPERFAMILY SSF53686 8 383 1.44E-134 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 Gene3D G3DSA:3.40.50.1100 207 388 2.3E-39 T 29-03-2018 A616_RS04330 3484f34700c7f0ab85e25a7c569e6f4b 388 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 372 7.5E-52 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 Pfam PF12836 Helix-hairpin-helix motif 171 231 7.2E-23 T 29-03-2018 A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 SMART SM00278 211 230 0.41 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 SMART SM00278 181 200 3.4E-4 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 SUPERFAMILY SSF47781 161 233 3.0E-29 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 Pfam PF10531 SLBB domain 88 138 5.0E-14 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 SUPERFAMILY SSF142984 89 122 8.37E-5 T 29-03-2018 A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 171 233 8.4E-20 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 Gene3D G3DSA:1.10.150.20 102 190 2.0E-11 T 29-03-2018 A616_RS11255 666ca53fd2cc936aea6a0a70643f5463 234 Gene3D G3DSA:1.10.150.310 191 234 2.9E-17 T 29-03-2018 A616_RS01690 5615e4a2b061e98bc446a1f8ff374a6e 52 SUPERFAMILY SSF140500 6 49 3.01E-8 T 29-03-2018 A616_RS01690 5615e4a2b061e98bc446a1f8ff374a6e 52 Pfam PF09388 Spo0E like sporulation regulatory protein 10 47 5.5E-9 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A616_RS31805 460fa11b373dd296434ce9df85f2720f 314 Gene3D G3DSA:3.40.1190.20 43 313 1.5E-46 T 29-03-2018 IPR029056 Ribokinase-like A616_RS31805 460fa11b373dd296434ce9df85f2720f 314 SUPERFAMILY SSF53613 1 300 3.12E-67 T 29-03-2018 IPR029056 Ribokinase-like A616_RS31805 460fa11b373dd296434ce9df85f2720f 314 PIRSF PIRSF000535 1 312 1.3E-75 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A616_RS31805 460fa11b373dd296434ce9df85f2720f 314 Pfam PF00294 pfkB family carbohydrate kinase 7 294 4.8E-49 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB A616_RS31805 460fa11b373dd296434ce9df85f2720f 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 3 306 7.8E-88 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 A616_RS31805 460fa11b373dd296434ce9df85f2720f 314 Gene3D G3DSA:2.20.150.10 10 42 5.5E-14 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain A616_RS14755 38f26e8eb55447d3bde47a4133f3d584 295 SUPERFAMILY SSF103481 38 136 3.01E-15 T 29-03-2018 A616_RS14755 38f26e8eb55447d3bde47a4133f3d584 295 SUPERFAMILY SSF103481 183 285 7.19E-12 T 29-03-2018 A616_RS14755 38f26e8eb55447d3bde47a4133f3d584 295 Pfam PF00892 EamA-like transporter family 146 282 2.6E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS14755 38f26e8eb55447d3bde47a4133f3d584 295 Pfam PF00892 EamA-like transporter family 4 136 1.3E-26 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS21425 af90b5367ed19df8382b5980179143b5 125 Gene3D G3DSA:3.40.30.10 10 125 2.8E-34 T 29-03-2018 A616_RS21425 af90b5367ed19df8382b5980179143b5 125 SUPERFAMILY SSF52833 12 124 3.1E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS21425 af90b5367ed19df8382b5980179143b5 125 Pfam PF03960 ArsC family 19 121 8.1E-18 T 29-03-2018 IPR006660 Arsenate reductase-like A616_RS21425 af90b5367ed19df8382b5980179143b5 125 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 12 122 2.2E-37 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 Pfam PF01544 CorA-like Mg2+ transporter protein 32 320 5.3E-64 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 Gene3D G3DSA:3.30.460.20 1 137 2.0E-31 T 29-03-2018 A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 SUPERFAMILY SSF144083 260 323 1.27E-13 T 29-03-2018 A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 SUPERFAMILY SSF143865 2 257 6.8E-67 T 29-03-2018 A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 Gene3D G3DSA:1.20.58.340 257 325 2.3E-19 T 29-03-2018 A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 Gene3D G3DSA:1.20.58.340 139 256 2.5E-26 T 29-03-2018 A616_RS10695 9c007aa4ed640d7f88fbab44fec23736 325 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 30 325 3.1E-65 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A616_RS11095 5600052c64dcb544a26ae3b972499b7d 142 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 4 139 22.758 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC A616_RS11095 5600052c64dcb544a26ae3b972499b7d 142 PIRSF PIRSF036659 1 142 2.5E-53 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC A616_RS11095 5600052c64dcb544a26ae3b972499b7d 142 Pfam PF02600 Disulfide bond formation protein DsbB 11 134 1.1E-13 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 A616_RS11095 5600052c64dcb544a26ae3b972499b7d 142 SUPERFAMILY SSF158442 12 136 3.53E-32 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain A616_RS11095 5600052c64dcb544a26ae3b972499b7d 142 Gene3D G3DSA:1.20.1550.10 1 117 2.2E-26 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain A616_RS21985 3ce9b761288292aaacf1923c3074d72f 395 Pfam PF03616 Sodium/glutamate symporter 4 363 1.1E-132 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A616_RS21985 3ce9b761288292aaacf1923c3074d72f 395 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 3 394 23.518 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A616_RS21985 3ce9b761288292aaacf1923c3074d72f 395 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 5 391 8.4E-116 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 213 4.3E-29 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 Gene3D G3DSA:3.40.1010.10 12 122 5.8E-42 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 PIRSF PIRSF005917 3 290 2.4E-104 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 232 38.188 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 SUPERFAMILY SSF53790 13 230 3.27E-84 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 288 1.3E-80 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 Gene3D G3DSA:3.30.950.10 123 235 9.1E-43 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 92 103 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS00605 21a047f61896ede01f4fe1c423ad61a0 290 Gene3D G3DSA:1.10.10.60 246 289 1.4E-4 T 29-03-2018 A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 Gene3D G3DSA:1.10.3210.10 359 574 2.0E-49 T 29-03-2018 A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 Gene3D G3DSA:3.30.450.20 170 296 2.8E-6 T 29-03-2018 A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 SUPERFAMILY SSF109604 382 563 1.4E-38 T 29-03-2018 A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 SMART SM00304 318 370 5.5E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 SUPERFAMILY SSF158472 319 368 3.66E-7 T 29-03-2018 A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 SMART SM00471 394 532 4.1E-12 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS00495 57b9626f44ef98d78a93101505a5ef0d 586 Pfam PF01966 HD domain 399 523 1.4E-19 T 29-03-2018 IPR006674 HD domain A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 Pfam PF00188 Cysteine-rich secretory protein family 248 362 1.9E-13 T 29-03-2018 IPR014044 CAP domain A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 Gene3D G3DSA:1.10.101.10 24 106 5.5E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 Gene3D G3DSA:1.10.101.10 118 198 4.3E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 SUPERFAMILY SSF47090 31 102 5.23E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 Pfam PF01471 Putative peptidoglycan binding domain 41 96 5.9E-10 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 Pfam PF01471 Putative peptidoglycan binding domain 134 188 4.7E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 Gene3D G3DSA:3.40.33.10 238 364 1.1E-13 T 29-03-2018 IPR014044 CAP domain A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 SUPERFAMILY SSF55797 241 362 2.88E-17 T 29-03-2018 IPR014044 CAP domain A616_RS10045 f2d95a943594714572b4f5ca7c281457 365 SUPERFAMILY SSF47090 125 190 1.57E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS23765 50812d171a9ac21a39a5f48c7384aa86 68 Gene3D G3DSA:1.10.287.760 6 66 1.1E-19 T 29-03-2018 IPR023164 YqgQ-like domain A616_RS23765 50812d171a9ac21a39a5f48c7384aa86 68 SUPERFAMILY SSF158379 6 64 1.7E-16 T 29-03-2018 IPR023164 YqgQ-like domain A616_RS23765 50812d171a9ac21a39a5f48c7384aa86 68 Pfam PF06014 Bacterial protein of unknown function (DUF910) 8 63 2.2E-19 T 29-03-2018 IPR009256 Protein of unknown function DUF910 A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 SUPERFAMILY SSF52540 442 683 6.35E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 SUPERFAMILY SSF52540 687 945 3.39E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 Pfam PF12419 SNF2 Helicase protein 282 413 5.8E-36 T 29-03-2018 IPR022138 Helicase SWF/SNF-related A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 Pfam PF00176 SNF2 family N-terminal domain 470 753 4.1E-57 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 Gene3D G3DSA:3.40.50.300 753 925 1.5E-35 T 29-03-2018 A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 SMART SM00487 465 655 3.0E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 Pfam PF00271 Helicase conserved C-terminal domain 769 887 3.8E-16 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 SMART SM00490 798 887 8.5E-18 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS14615 a7dc0c7334934ea1f4dc9454a83aa7f7 952 Gene3D G3DSA:3.40.50.10810 435 689 1.6E-53 T 29-03-2018 A616_RS27220 803ec5388bac28d329bb3ec77315189e 336 SUPERFAMILY SSF53822 49 273 5.14E-13 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS27220 803ec5388bac28d329bb3ec77315189e 336 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 46 316 3.4E-44 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A616_RS27220 803ec5388bac28d329bb3ec77315189e 336 Gene3D G3DSA:3.40.50.2300 45 160 5.9E-22 T 29-03-2018 A616_RS27220 803ec5388bac28d329bb3ec77315189e 336 Gene3D G3DSA:3.40.50.2300 161 331 3.5E-26 T 29-03-2018 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 SUPERFAMILY SSF55874 291 458 1.14E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 SMART SM00388 235 301 8.8E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 459 7.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 Gene3D G3DSA:3.30.565.10 308 460 5.9E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 Gene3D G3DSA:1.10.287.130 226 296 1.2E-13 T 29-03-2018 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 299 3.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 SUPERFAMILY SSF47384 223 299 2.16E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 SMART SM00387 347 460 7.9E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.4E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 1.4E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS17970 aba86271395a906a1a0c3fbec7c82ae9 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 1.4E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS22100 d128aa3a595165e20cc6d56f1e0a2774 178 SMART SM00793 4 176 5.5E-6 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 A616_RS22100 d128aa3a595165e20cc6d56f1e0a2774 178 Pfam PF04647 Accessory gene regulator B 7 151 2.5E-18 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 A616_RS08995 87d81ce961575e9ee3481959beaebd02 426 Pfam PF05977 Transmembrane secretion effector 9 409 4.7E-32 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS08995 87d81ce961575e9ee3481959beaebd02 426 Gene3D G3DSA:1.20.1250.20 203 421 2.6E-20 T 29-03-2018 A616_RS08995 87d81ce961575e9ee3481959beaebd02 426 SUPERFAMILY SSF103473 12 405 5.36E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS08995 87d81ce961575e9ee3481959beaebd02 426 Gene3D G3DSA:1.20.1250.20 3 202 6.5E-21 T 29-03-2018 A616_RS00260 af19ab18f92e32e9fd4b3708c18751e2 281 SUPERFAMILY SSF161098 8 275 1.7E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS00260 af19ab18f92e32e9fd4b3708c18751e2 281 Gene3D G3DSA:1.10.3720.10 7 280 1.2E-34 T 29-03-2018 A616_RS00260 af19ab18f92e32e9fd4b3708c18751e2 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 277 2.5E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09975 09d232689752bb5fccee45310b63724e 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 441 4.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09975 09d232689752bb5fccee45310b63724e 442 SUPERFAMILY SSF55874 307 441 1.01E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09975 09d232689752bb5fccee45310b63724e 442 SMART SM00387 331 442 2.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09975 09d232689752bb5fccee45310b63724e 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 440 2.2E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS09975 09d232689752bb5fccee45310b63724e 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 2.2E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS09975 09d232689752bb5fccee45310b63724e 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 2.2E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS09975 09d232689752bb5fccee45310b63724e 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 2.2E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS09975 09d232689752bb5fccee45310b63724e 442 SUPERFAMILY SSF103190 76 187 2.67E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS09975 09d232689752bb5fccee45310b63724e 442 Gene3D G3DSA:3.30.450.20 35 189 5.2E-12 T 29-03-2018 A616_RS09975 09d232689752bb5fccee45310b63724e 442 Gene3D G3DSA:3.30.565.10 298 442 2.6E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09975 09d232689752bb5fccee45310b63724e 442 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 236 288 9.1E-14 T 29-03-2018 A616_RS09975 09d232689752bb5fccee45310b63724e 442 Gene3D G3DSA:1.10.287.130 233 291 1.3E-13 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 Gene3D G3DSA:2.40.50.100 64 129 1.7E-15 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 Pfam PF13533 Biotin-lipoyl like 64 111 1.4E-12 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 173 325 3.0E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 194 407 2.0E-39 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 SUPERFAMILY SSF111369 200 329 1.14E-12 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 SUPERFAMILY SSF111369 134 169 1.14E-12 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 Gene3D G3DSA:1.20.1600.10 193 278 1.8E-4 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 SUPERFAMILY SSF111369 56 124 4.58E-8 T 29-03-2018 A616_RS18605 bdf513fe4bbc53919217e2e446cb87c1 408 Gene3D G3DSA:1.10.287.470 131 190 1.3E-10 T 29-03-2018 A616_RS20620 e75327e3055706279b81656804e08d45 621 SUPERFAMILY SSF52540 349 593 1.07E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20620 e75327e3055706279b81656804e08d45 621 Pfam PF00664 ABC transporter transmembrane region 68 291 2.9E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS20620 e75327e3055706279b81656804e08d45 621 SUPERFAMILY SSF90123 12 344 1.03E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS20620 e75327e3055706279b81656804e08d45 621 SMART SM00382 384 570 6.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20620 e75327e3055706279b81656804e08d45 621 Gene3D G3DSA:1.20.1560.10 6 340 3.3E-35 T 29-03-2018 A616_RS20620 e75327e3055706279b81656804e08d45 621 Gene3D G3DSA:3.40.50.300 341 600 1.5E-68 T 29-03-2018 A616_RS20620 e75327e3055706279b81656804e08d45 621 Pfam PF00005 ABC transporter 375 524 1.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14160 9d1d9e48a72a8ed47130887088ccc123 458 Gene3D G3DSA:3.40.50.1100 98 234 1.3E-25 T 29-03-2018 A616_RS14160 9d1d9e48a72a8ed47130887088ccc123 458 Gene3D G3DSA:3.40.50.1100 235 445 3.8E-29 T 29-03-2018 A616_RS14160 9d1d9e48a72a8ed47130887088ccc123 458 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 18 441 1.9E-210 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 A616_RS14160 9d1d9e48a72a8ed47130887088ccc123 458 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 458 250.191 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 A616_RS14160 9d1d9e48a72a8ed47130887088ccc123 458 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 81 400 4.4E-59 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS14160 9d1d9e48a72a8ed47130887088ccc123 458 SUPERFAMILY SSF53686 56 440 2.19E-58 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 SUPERFAMILY SSF52540 5 169 1.23E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Gene3D G3DSA:3.30.300.20 358 435 1.6E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 354 434 1.9E-34 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 340 3.9E-28 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 126 1.2E-21 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 SUPERFAMILY SSF52540 139 436 6.14E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Hamap MF_00195 GTPase Der [der]. 3 437 41.1 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 249 267 5.5E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 179 199 5.5E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Pfam PF01926 50S ribosome-binding GTPase 6 121 1.2E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Pfam PF01926 50S ribosome-binding GTPase 178 296 1.2E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Gene3D G3DSA:1.20.120.430 3 70 1.3E-17 T 29-03-2018 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Gene3D G3DSA:1.20.120.430 243 357 6.9E-14 T 29-03-2018 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 Gene3D G3DSA:1.20.120.430 71 242 2.6E-43 T 29-03-2018 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 PIRSF PIRSF006485 2 437 3.0E-173 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A616_RS13670 d2fdb437999b11d9a69cb8aba7bb7d23 437 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 433 6.5E-177 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 Gene3D G3DSA:1.10.1660.10 56 125 2.3E-13 T 29-03-2018 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 SMART SM00422 2 70 2.5E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 Pfam PF13411 MerR HTH family regulatory protein 2 67 6.8E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 1.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 1.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 SUPERFAMILY SSF46955 2 114 1.21E-31 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS08520 7718bf6822bbecaa022589fd83621fa4 126 Gene3D G3DSA:1.10.1660.10 1 55 3.3E-23 T 29-03-2018 A616_RS24130 8e9778e4f2426525e705860e62369812 397 Gene3D G3DSA:3.40.630.10 1 272 1.1E-64 T 29-03-2018 A616_RS24130 8e9778e4f2426525e705860e62369812 397 SUPERFAMILY SSF55031 189 301 6.28E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS24130 8e9778e4f2426525e705860e62369812 397 PIRSF PIRSF005962 2 396 2.0E-131 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS24130 8e9778e4f2426525e705860e62369812 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 380 2.7E-121 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS24130 8e9778e4f2426525e705860e62369812 397 Pfam PF07687 Peptidase dimerisation domain 191 282 8.1E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS24130 8e9778e4f2426525e705860e62369812 397 Pfam PF01546 Peptidase family M20/M25/M40 77 384 5.4E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS24130 8e9778e4f2426525e705860e62369812 397 SUPERFAMILY SSF53187 5 202 9.29E-88 T 29-03-2018 A616_RS24130 8e9778e4f2426525e705860e62369812 397 SUPERFAMILY SSF53187 303 393 9.29E-88 T 29-03-2018 A616_RS24130 8e9778e4f2426525e705860e62369812 397 Gene3D G3DSA:3.40.630.10 273 396 1.3E-22 T 29-03-2018 A616_RS05685 e496c88776e6cbd6bfc61ee23dd14c25 173 Pfam PF00877 NlpC/P60 family 38 143 4.8E-29 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS05685 e496c88776e6cbd6bfc61ee23dd14c25 173 Gene3D G3DSA:3.90.1720.10 21 155 2.3E-39 T 29-03-2018 A616_RS05685 e496c88776e6cbd6bfc61ee23dd14c25 173 SUPERFAMILY SSF54001 28 144 5.89E-40 T 29-03-2018 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SUPERFAMILY SSF47384 351 435 4.32E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Gene3D G3DSA:3.30.450.20 248 363 5.8E-14 T 29-03-2018 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Gene3D G3DSA:3.30.450.20 32 177 5.7E-4 T 29-03-2018 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 1.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 1.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 1.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 1.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Gene3D G3DSA:1.10.287.130 364 428 6.3E-18 T 29-03-2018 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SMART SM00304 204 256 5.5E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SUPERFAMILY SSF55785 250 359 3.56E-11 T 29-03-2018 IPR000014 PAS domain A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SUPERFAMILY SSF55874 423 588 1.22E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 588 4.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SMART SM00387 480 592 3.4E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SMART SM00388 367 434 6.1E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Pfam PF00512 His Kinase A (phospho-acceptor) domain 367 434 3.4E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Pfam PF00672 HAMP domain 209 252 2.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 Gene3D G3DSA:3.30.565.10 429 592 1.2E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13520 069849b75319a2003ec6104b3a4ad294 594 SUPERFAMILY SSF158472 205 255 6.02E-12 T 29-03-2018 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 40.041 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.8E-93 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 SUPERFAMILY SSF55920 1 247 3.53E-87 T 29-03-2018 IPR000994 Peptidase M24 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 Gene3D G3DSA:3.90.230.10 1 248 1.3E-82 T 29-03-2018 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.9E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.9E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.9E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.9E-19 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS22495 40b62ecf76d8795e16bae38cd4f05a7d 248 Pfam PF00557 Metallopeptidase family M24 11 239 9.3E-53 T 29-03-2018 IPR000994 Peptidase M24 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 Pfam PF08281 Sigma-70, region 4 117 169 1.9E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 Gene3D G3DSA:1.10.10.10 101 180 9.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13015 c84758ffaaeef47f99b100302813116e 189 Gene3D G3DSA:1.10.1740.10 2 100 8.7E-28 T 29-03-2018 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 SUPERFAMILY SSF88946 3 106 3.45E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 SUPERFAMILY SSF88659 106 173 4.58E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 171 8.2E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 Pfam PF04542 Sigma-70 region 2 22 89 2.3E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS13015 c84758ffaaeef47f99b100302813116e 189 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 44 75 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 PIRSF PIRSF000709 2 152 1.8E-12 T 29-03-2018 A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 188 6.5E-57 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 Gene3D G3DSA:3.40.50.1240 2 193 6.6E-53 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 SUPERFAMILY SSF53254 4 191 5.41E-54 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 SMART SM00855 4 149 8.1E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 PRINTS PR00991 6-phosphofructo-2-kinase family signature 86 102 2.1E-6 T 29-03-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|KEGG: 00500+2.7.1.10|Reactome: R-HSA-70171 A616_RS22940 8556316c22a3e1d4424836fde1c8fff8 193 PRINTS PR00991 6-phosphofructo-2-kinase family signature 5 27 2.1E-6 T 29-03-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|KEGG: 00500+2.7.1.10|Reactome: R-HSA-70171 A616_RS14150 4f65052cf7e1a87e8f89068c35e41951 150 Pfam PF00583 Acetyltransferase (GNAT) family 29 115 2.1E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS14150 4f65052cf7e1a87e8f89068c35e41951 150 Gene3D G3DSA:3.40.630.30 1 150 3.3E-29 T 29-03-2018 A616_RS14150 4f65052cf7e1a87e8f89068c35e41951 150 SUPERFAMILY SSF55729 14 146 6.65E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS01405 66bc0125b231ab7a4db7f1a7d320d4b4 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 38.047 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01405 66bc0125b231ab7a4db7f1a7d320d4b4 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 5.0E-83 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01405 66bc0125b231ab7a4db7f1a7d320d4b4 207 SUPERFAMILY SSF52166 1 206 3.01E-83 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A616_RS01405 66bc0125b231ab7a4db7f1a7d320d4b4 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 8.1E-73 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A616_RS01405 66bc0125b231ab7a4db7f1a7d320d4b4 207 Gene3D G3DSA:3.40.1370.10 145 205 1.7E-16 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A616_RS01405 66bc0125b231ab7a4db7f1a7d320d4b4 207 Gene3D G3DSA:3.40.1370.10 2 144 8.6E-59 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 Gene3D G3DSA:3.90.660.20 215 413 1.5E-37 T 29-03-2018 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 Pfam PF01593 Flavin containing amine oxidoreductase 15 457 4.8E-61 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 Gene3D G3DSA:3.90.660.10 35 118 0.025 T 29-03-2018 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 Gene3D G3DSA:1.10.3110.10 119 211 7.8E-30 T 29-03-2018 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 SUPERFAMILY SSF54373 309 412 6.91E-29 T 29-03-2018 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 6 460 1.3E-115 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 SUPERFAMILY SSF51905 430 457 2.85E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10405 5290ab510193b84a42ee81b1948dff7a 469 SUPERFAMILY SSF51905 6 321 2.85E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS17440 aa10e17e24985dace68754e605382927 204 Pfam PF05709 Phage tail protein 39 140 1.3E-8 T 29-03-2018 IPR008841 Siphovirus-type tail component A616_RS13860 9eb5719889a08802468deb318ae478cf 216 Pfam PF13490 Putative zinc-finger 4 38 2.6E-9 T 29-03-2018 IPR027383 Putative zinc-finger A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 SUPERFAMILY SSF55594 1 83 4.97E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.7E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.7E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.7E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 Gene3D G3DSA:3.30.1340.10 1 85 2.4E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 4.8E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 Pfam PF00381 PTS HPr component phosphorylation site 2 82 3.8E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30805 de4d15f75d41231c3d5d7e0b511f38a3 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A616_RS30800 50b9092302affb117c669a74ca300ecb 558 Gene3D G3DSA:3.40.720.10 9 449 1.8E-56 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS30800 50b9092302affb117c669a74ca300ecb 558 SUPERFAMILY SSF53649 9 126 5.76E-69 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS30800 50b9092302affb117c669a74ca300ecb 558 SUPERFAMILY SSF53649 161 443 5.76E-69 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS30800 50b9092302affb117c669a74ca300ecb 558 SUPERFAMILY SSF53649 473 534 5.76E-69 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS30800 50b9092302affb117c669a74ca300ecb 558 Gene3D G3DSA:3.30.1120.10 468 552 6.6E-7 T 29-03-2018 A616_RS30800 50b9092302affb117c669a74ca300ecb 558 Pfam PF00884 Sulfatase 10 394 1.9E-47 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 Gene3D G3DSA:1.20.140.10 217 381 2.6E-60 T 29-03-2018 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 SUPERFAMILY SSF56645 2 240 3.27E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 Gene3D G3DSA:2.40.110.10 121 216 1.5E-30 T 29-03-2018 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 SUPERFAMILY SSF47203 227 379 3.06E-56 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 2.2E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.1E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 Gene3D G3DSA:1.10.540.10 1 120 1.5E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS15420 c75ae424b87f8e389cf8c983454c6079 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 216 3.6E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS13545 b6656a298b201f58690f0ec4eeb820ba 384 Gene3D G3DSA:3.90.1150.10 268 384 5.8E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS13545 b6656a298b201f58690f0ec4eeb820ba 384 Gene3D G3DSA:3.40.640.10 14 267 9.8E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS13545 b6656a298b201f58690f0ec4eeb820ba 384 SUPERFAMILY SSF53383 5 364 1.1E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS13545 b6656a298b201f58690f0ec4eeb820ba 384 PIRSF PIRSF000524 1 383 3.5E-144 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 A616_RS13545 b6656a298b201f58690f0ec4eeb820ba 384 Pfam PF00266 Aminotransferase class-V 8 335 2.0E-45 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS13545 b6656a298b201f58690f0ec4eeb820ba 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 184 204 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 306 322 1.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 306 1.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 Gene3D G3DSA:2.60.120.10 16 127 2.9E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 SUPERFAMILY SSF46689 275 324 2.24E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 Pfam PF12833 Helix-turn-helix domain 245 323 1.9E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 Gene3D G3DSA:1.10.10.60 276 325 6.3E-13 T 29-03-2018 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 Gene3D G3DSA:1.10.10.60 215 275 4.7E-9 T 29-03-2018 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 276 318 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 SUPERFAMILY SSF46689 223 273 1.08E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25950 2844ca7720ec15da2bde3eee3f3f2b6e 327 SMART SM00342 239 322 1.4E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS01820 664315f7e53f44ed0dcf8d660ee997d0 313 SUPERFAMILY SSF53474 45 308 2.92E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01820 664315f7e53f44ed0dcf8d660ee997d0 313 Gene3D G3DSA:3.40.50.1820 3 313 4.1E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01820 664315f7e53f44ed0dcf8d660ee997d0 313 Pfam PF07859 alpha/beta hydrolase fold 77 285 4.4E-66 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1 72 4.4E-5 T 29-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 2.0E-108 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 Pfam PF01628 HrcA protein C terminal domain 104 321 1.6E-67 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 PIRSF PIRSF005485 1 339 1.0E-118 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 SUPERFAMILY SSF55781 71 337 3.73E-69 T 29-03-2018 IPR029016 GAF domain-like A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 32.071 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 SUPERFAMILY SSF46785 1 81 2.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 Gene3D G3DSA:1.10.10.10 1 84 7.1E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11460 6df550860af58994fefc27f5fef4aee0 341 Gene3D G3DSA:3.30.450.40 185 341 2.5E-43 T 29-03-2018 IPR029016 GAF domain-like A616_RS26655 5d023a3690f794c3f1e24a07da0ee90a 285 Pfam PF01904 Protein of unknown function DUF72 18 267 1.1E-62 T 29-03-2018 IPR002763 Protein of unknown function DUF72 A616_RS26655 5d023a3690f794c3f1e24a07da0ee90a 285 Gene3D G3DSA:3.20.20.410 1 283 1.4E-85 T 29-03-2018 IPR002763 Protein of unknown function DUF72 A616_RS26655 5d023a3690f794c3f1e24a07da0ee90a 285 SUPERFAMILY SSF117396 3 269 3.27E-81 T 29-03-2018 IPR002763 Protein of unknown function DUF72 A616_RS08640 743c79c16ced1298dfdb61e24e49b2b3 88 Gene3D G3DSA:1.10.10.60 45 88 3.4E-12 T 29-03-2018 A616_RS08640 743c79c16ced1298dfdb61e24e49b2b3 88 SUPERFAMILY SSF46689 1 88 5.73E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS20520 ea719306836708f3fb8e4adba186ae75 456 SMART SM00327 250 420 0.0032 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS20520 ea719306836708f3fb8e4adba186ae75 456 Pfam PF01882 Protein of unknown function DUF58 211 296 8.4E-20 T 29-03-2018 IPR002881 Domain of unknown function DUF58 A616_RS20520 ea719306836708f3fb8e4adba186ae75 456 SUPERFAMILY SSF53300 247 385 6.49E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS20520 ea719306836708f3fb8e4adba186ae75 456 Gene3D G3DSA:3.40.50.410 223 410 4.6E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 PRINTS PR00070 Dihydrofolate reductase signature 87 101 8.5E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 PRINTS PR00070 Dihydrofolate reductase signature 13 23 8.5E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 PRINTS PR00070 Dihydrofolate reductase signature 27 35 8.5E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 PRINTS PR00070 Dihydrofolate reductase signature 40 51 8.5E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 SUPERFAMILY SSF53597 1 157 2.36E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 Pfam PF00186 Dihydrofolate reductase 1 155 1.0E-58 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 Gene3D G3DSA:3.40.430.10 1 158 9.1E-52 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS24140 e672bcb0e773a11f88c44f5d7e648f6a 158 PIRSF PIRSF000194 1 158 1.0E-57 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS11560 f60ecca0aa65c87dfd0606f64eecd117 88 Gene3D G3DSA:1.10.1200.10 4 82 5.3E-12 T 29-03-2018 A616_RS11560 f60ecca0aa65c87dfd0606f64eecd117 88 Pfam PF00550 Phosphopantetheine attachment site 9 78 7.1E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS11560 f60ecca0aa65c87dfd0606f64eecd117 88 SUPERFAMILY SSF47336 5 80 3.8E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS02965 e3d301d0b888dd81843f3bd285347ecb 166 Pfam PF12207 Domain of unknown function (DUF3600) 70 164 2.5E-10 T 29-03-2018 IPR022019 Domain of unknown function DUF3600 A616_RS02965 e3d301d0b888dd81843f3bd285347ecb 166 Gene3D G3DSA:1.10.3950.10 72 166 5.8E-24 T 29-03-2018 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SMART SM00304 189 241 9.6E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Gene3D G3DSA:3.30.450.20 245 368 6.7E-21 T 29-03-2018 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Pfam PF00672 HAMP domain 190 237 2.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SUPERFAMILY SSF103190 76 164 4.32E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Gene3D G3DSA:3.30.565.10 425 587 3.4E-51 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Gene3D G3DSA:3.30.450.20 29 163 1.0E-28 T 29-03-2018 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SMART SM00091 248 315 6.5E-4 T 29-03-2018 IPR000014 PAS domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SMART SM00387 476 587 2.2E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 363 429 2.1E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SUPERFAMILY SSF55874 420 586 5.76E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Gene3D G3DSA:1.10.287.130 369 424 2.7E-20 T 29-03-2018 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Pfam PF16736 Single Cache-like 33 150 7.3E-11 T 29-03-2018 IPR031967 PhoR, single Cache-like domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 587 6.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 Pfam PF00989 PAS fold 249 354 3.6E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SMART SM00388 363 430 1.3E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SUPERFAMILY SSF55785 237 355 2.09E-12 T 29-03-2018 IPR000014 PAS domain A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SUPERFAMILY SSF158472 190 239 4.05E-10 T 29-03-2018 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 SUPERFAMILY SSF47384 348 430 1.61E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 541 1.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 585 1.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 527 1.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 1.4E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS08010 d2cc23335faaceeab83200fc1ede9f96 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 245 362 4.7E-11 T 29-03-2018 IPR000014 PAS domain A616_RS30485 9cb7dd75a6e35f8b798adb38f8f4263e 318 SUPERFAMILY SSF160964 29 83 6.41E-7 T 29-03-2018 A616_RS30485 9cb7dd75a6e35f8b798adb38f8f4263e 318 SUPERFAMILY SSF161098 79 305 1.57E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS30485 9cb7dd75a6e35f8b798adb38f8f4263e 318 Gene3D G3DSA:1.10.3720.10 84 316 1.1E-42 T 29-03-2018 A616_RS30485 9cb7dd75a6e35f8b798adb38f8f4263e 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 305 3.0E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS30485 9cb7dd75a6e35f8b798adb38f8f4263e 318 Gene3D G3DSA:1.20.58.370 22 67 1.5E-8 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS29340 5f1b463d262f9e46d4ac1dd301abbd3c 183 Pfam PF17248 Family of unknown function (DUF5317) 26 161 9.6E-28 T 29-03-2018 IPR035168 Protein of unknown function DUF5317 A616_RS15390 f3b984eded104d41723a067fbf413098 534 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 517 3.8E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS15390 f3b984eded104d41723a067fbf413098 534 SUPERFAMILY SSF56801 16 526 1.7E-149 T 29-03-2018 A616_RS15390 f3b984eded104d41723a067fbf413098 534 Gene3D G3DSA:2.30.38.10 340 427 4.5E-24 T 29-03-2018 A616_RS15390 f3b984eded104d41723a067fbf413098 534 Gene3D G3DSA:3.40.50.980 25 191 4.2E-45 T 29-03-2018 A616_RS15390 f3b984eded104d41723a067fbf413098 534 Pfam PF00501 AMP-binding enzyme 32 434 1.9E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15390 f3b984eded104d41723a067fbf413098 534 Gene3D G3DSA:3.30.300.30 428 530 1.3E-27 T 29-03-2018 A616_RS15390 f3b984eded104d41723a067fbf413098 534 Gene3D G3DSA:3.40.50.980 192 339 2.1E-42 T 29-03-2018 A616_RS15390 f3b984eded104d41723a067fbf413098 534 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 Gene3D G3DSA:1.10.1740.10 1 90 6.9E-25 T 29-03-2018 A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 SUPERFAMILY SSF88946 3 105 1.83E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 Pfam PF04542 Sigma-70 region 2 23 90 2.1E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 173 6.3E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 SUPERFAMILY SSF88659 106 173 2.99E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 Gene3D G3DSA:1.10.10.10 91 176 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02310 835d608ce5c363f63998d7cdc6cd33a0 188 Pfam PF08281 Sigma-70, region 4 119 169 2.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05730 4527317d1af9d1daf9fa090a1417a1c4 76 Pfam PF03672 Uncharacterised protein family (UPF0154) 10 67 8.4E-18 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 A616_RS10560 f1f4fe55553ee7fb6fc4274937819b6b 116 SUPERFAMILY SSF118010 1 108 2.09E-26 T 29-03-2018 IPR007422 Cysteine protease Prp A616_RS10560 f1f4fe55553ee7fb6fc4274937819b6b 116 Pfam PF04327 Cysteine protease Prp 1 106 3.3E-21 T 29-03-2018 IPR007422 Cysteine protease Prp A616_RS10560 f1f4fe55553ee7fb6fc4274937819b6b 116 Gene3D G3DSA:3.30.70.1490 1 112 1.0E-25 T 29-03-2018 IPR007422 Cysteine protease Prp A616_RS07245 3d710e821799f12b61e3f40abca631f6 176 SUPERFAMILY SSF52833 1 174 3.75E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS07245 3d710e821799f12b61e3f40abca631f6 176 PIRSF PIRSF000239 1 176 7.7E-53 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS07245 3d710e821799f12b61e3f40abca631f6 176 Gene3D G3DSA:3.40.30.10 1 152 1.3E-34 T 29-03-2018 A616_RS07245 3d710e821799f12b61e3f40abca631f6 176 Pfam PF00578 AhpC/TSA family 5 136 2.5E-35 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS07245 3d710e821799f12b61e3f40abca631f6 176 Gene3D G3DSA:3.30.1020.10 153 176 8.2E-6 T 29-03-2018 A616_RS25750 10fa7fb2762f396fe97e5c53e0c5f2c7 382 Gene3D G3DSA:3.40.50.1970 9 181 1.0E-47 T 29-03-2018 A616_RS25750 10fa7fb2762f396fe97e5c53e0c5f2c7 382 Gene3D G3DSA:1.20.1090.10 184 382 4.1E-57 T 29-03-2018 A616_RS25750 10fa7fb2762f396fe97e5c53e0c5f2c7 382 SUPERFAMILY SSF56796 6 381 1.11E-120 T 29-03-2018 A616_RS25750 10fa7fb2762f396fe97e5c53e0c5f2c7 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 374 1.2E-115 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A616_RS27465 526021706fa65f3e907be556f3d968fa 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 299 1.9E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS27465 526021706fa65f3e907be556f3d968fa 342 Gene3D G3DSA:1.10.3470.10 30 305 2.2E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SUPERFAMILY SSF48403 27 219 2.01E-46 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 PIRSF PIRSF000654 3 122 5.4E-13 T 29-03-2018 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 PIRSF PIRSF000654 108 221 1.3E-13 T 29-03-2018 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 Gene3D G3DSA:1.25.40.20 132 221 7.1E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 Gene3D G3DSA:1.25.40.20 4 131 3.5E-30 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 Pfam PF12796 Ankyrin repeats (3 copies) 96 193 1.6E-12 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 Pfam PF12796 Ankyrin repeats (3 copies) 26 88 9.0E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SMART SM00248 157 191 0.11 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SMART SM00248 57 86 0.0063 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SMART SM00248 90 119 340.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SMART SM00248 195 221 1200.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SMART SM00248 24 53 100.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS04685 af7e04bbedcfcd8bd6ae38902edd7ac4 221 SMART SM00248 123 151 32.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 179 479 1.7E-35 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 ProSitePatterns PS00259 Gastrin / cholecystokinin family signature. 588 593 - T 29-03-2018 IPR013152 Gastrin/cholecystokinin, conserved site Reactome: R-HSA-416476 A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 Pfam PF12793 Sugar transport-related sRNA regulator N-term 3 102 1.0E-30 T 29-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 Gene3D G3DSA:3.40.190.10 285 379 6.8E-9 T 29-03-2018 A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 Gene3D G3DSA:1.10.10.10 2 69 0.0014 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 Gene3D G3DSA:3.90.76.10 145 284 5.7E-33 T 29-03-2018 A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 SUPERFAMILY SSF53850 135 597 3.98E-66 T 29-03-2018 A616_RS22310 d506fd19a06f6c4ad92c69da71eea233 600 Gene3D G3DSA:3.10.105.10 380 571 6.7E-7 T 29-03-2018 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 SUPERFAMILY SSF48498 90 196 3.47E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 Gene3D G3DSA:1.10.357.10 63 198 1.8E-11 T 29-03-2018 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 Gene3D G3DSA:1.10.10.60 1 62 1.5E-20 T 29-03-2018 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 SUPERFAMILY SSF46689 6 86 2.77E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 96 185 1.8E-6 T 29-03-2018 A616_RS14890 433e3b6771c21ec0aa8d223d00dc1410 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.2E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14450 011f2390f0c24469d526df9b8a81c8fb 125 Gene3D G3DSA:3.40.30.10 8 108 1.2E-29 T 29-03-2018 A616_RS14450 011f2390f0c24469d526df9b8a81c8fb 125 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 9 86 1.8E-8 T 29-03-2018 A616_RS14450 011f2390f0c24469d526df9b8a81c8fb 125 SUPERFAMILY SSF52833 9 105 1.23E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Pfam PF13180 PDZ domain 120 196 5.3E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Gene3D G3DSA:2.30.42.10 119 198 2.5E-18 T 29-03-2018 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 SMART SM00228 119 190 7.2E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 SUPERFAMILY SSF52096 214 390 3.15E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 SUPERFAMILY SSF52096 55 137 3.15E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 SUPERFAMILY SSF50156 90 215 3.24E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Pfam PF01471 Putative peptidoglycan binding domain 407 461 7.5E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Gene3D G3DSA:3.90.226.10 199 398 1.3E-57 T 29-03-2018 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Pfam PF03572 Peptidase family S41 220 384 1.5E-49 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Gene3D G3DSA:3.30.750.44 18 118 1.0E-15 T 29-03-2018 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 SUPERFAMILY SSF47090 395 464 1.73E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 SMART SM00245 192 385 1.4E-58 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 Gene3D G3DSA:1.10.101.10 399 468 1.4E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS29285 f49483cb9fe8e672ecb132c36f8d8d15 489 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 71 390 3.9E-112 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Gene3D G3DSA:2.30.30.410 188 283 1.0E-6 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Gene3D G3DSA:2.30.30.410 39 112 6.8E-17 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 PIRSF PIRSF037846 15 127 7.0E-17 T 29-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 PIRSF PIRSF037846 108 368 9.1E-45 T 29-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 PIRSF PIRSF037846 365 622 2.0E-63 T 29-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Gene3D G3DSA:2.40.50.110 284 361 7.5E-19 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Gene3D G3DSA:2.40.50.110 113 181 9.2E-18 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Gene3D G3DSA:2.40.50.110 362 433 2.2E-13 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Gene3D G3DSA:3.40.630.40 434 628 2.2E-52 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SMART SM00646 509 618 1.0E-22 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SUPERFAMILY SSF50044 325 385 1.95E-5 T 29-03-2018 IPR001452 SH3 domain GO:0005515 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SMART SM00287 300 362 2.6E-18 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SMART SM00287 213 275 0.0036 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SMART SM00287 46 108 3.8E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SMART SM00287 371 433 8.4E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SMART SM00287 119 181 4.6E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 SUPERFAMILY SSF53187 446 622 8.16E-47 T 29-03-2018 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 449 618 1.6E-45 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Pfam PF08239 Bacterial SH3 domain 56 106 8.4E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Pfam PF08239 Bacterial SH3 domain 381 430 2.8E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Pfam PF08239 Bacterial SH3 domain 128 178 5.6E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS10755 1ca164eafbb3fc20f0b6b2bf34990a48 629 Pfam PF08239 Bacterial SH3 domain 308 360 3.0E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS18495 526291cbdf465e798aa467edc57d2939 347 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 43 137 7.4E-8 T 29-03-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 A616_RS18495 526291cbdf465e798aa467edc57d2939 347 Gene3D G3DSA:3.90.70.10 11 174 4.4E-4 T 29-03-2018 A616_RS15465 68dc953ed11f77c235f9059d155e89e8 538 Gene3D G3DSA:3.10.105.10 308 511 2.3E-55 T 29-03-2018 A616_RS15465 68dc953ed11f77c235f9059d155e89e8 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 454 3.0E-89 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS15465 68dc953ed11f77c235f9059d155e89e8 538 Gene3D G3DSA:3.40.190.10 212 307 8.4E-26 T 29-03-2018 A616_RS15465 68dc953ed11f77c235f9059d155e89e8 538 PIRSF PIRSF002741 2 533 4.4E-109 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS15465 68dc953ed11f77c235f9059d155e89e8 538 SUPERFAMILY SSF53850 53 526 5.25E-128 T 29-03-2018 A616_RS15465 68dc953ed11f77c235f9059d155e89e8 538 Gene3D G3DSA:3.90.76.10 64 211 3.5E-34 T 29-03-2018 A616_RS26340 7ba456aedbad60fc97a6bb0f4febfbbe 87 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 64 2.0E-15 T 29-03-2018 A616_RS26340 7ba456aedbad60fc97a6bb0f4febfbbe 87 Pfam PF07293 Protein of unknown function (DUF1450) 1 77 1.2E-32 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 A616_RS03955 93870c87b96f7f2a687a26e5d3aa3a5b 339 Gene3D G3DSA:1.10.3470.10 35 334 1.1E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS03955 93870c87b96f7f2a687a26e5d3aa3a5b 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 328 3.8E-47 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 Gene3D G3DSA:3.50.50.60 164 320 1.8E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 Gene3D G3DSA:3.50.50.60 6 163 1.5E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 6.3E-24 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 6.3E-24 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 6.3E-24 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 6.3E-24 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 SUPERFAMILY SSF51905 8 332 1.69E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 1.2E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 8.4E-17 T 29-03-2018 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 8.4E-17 T 29-03-2018 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 8.4E-17 T 29-03-2018 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 8.4E-17 T 29-03-2018 A616_RS14355 41529912439f41a483f8f244c6363b6e 348 Hamap MF_01685 Ferredoxin--NADP reductase. 7 330 38.398 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A616_RS10505 fb605d679095342db97830096d9fa096 174 Pfam PF04093 rod shape-determining protein MreD 3 164 6.4E-19 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A616_RS10505 fb605d679095342db97830096d9fa096 174 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 10 158 3.6E-20 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 SUPERFAMILY SSF55785 151 210 6.28E-5 T 29-03-2018 IPR000014 PAS domain A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 SUPERFAMILY SSF52540 273 516 2.13E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Pfam PF13188 PAS domain 155 197 7.6E-5 T 29-03-2018 IPR000014 PAS domain A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Gene3D G3DSA:3.30.450.20 152 261 3.4E-9 T 29-03-2018 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Gene3D G3DSA:1.10.10.60 553 592 5.4E-12 T 29-03-2018 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Gene3D G3DSA:1.10.8.60 448 552 7.3E-20 T 29-03-2018 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Gene3D G3DSA:3.30.450.40 3 151 2.5E-7 T 29-03-2018 IPR029016 GAF domain-like A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 556 573 2.1E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 573 593 2.1E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 297 310 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 SUPERFAMILY SSF46689 488 592 9.26E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Pfam PF02954 Bacterial regulatory protein, Fis family 547 590 9.9E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Gene3D G3DSA:3.40.50.300 270 447 1.8E-23 T 29-03-2018 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 Pfam PF00158 Sigma-54 interaction domain 275 442 7.3E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 SMART SM00382 293 438 5.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23325 e341d1d567dccb5e96c8b21fa9af125f 593 SMART SM00091 155 222 6.9E-4 T 29-03-2018 IPR000014 PAS domain A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 SUPERFAMILY SSF88659 122 179 2.8E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 Pfam PF04542 Sigma-70 region 2 25 90 7.9E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 Gene3D G3DSA:1.10.10.10 109 187 4.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 SUPERFAMILY SSF88946 2 99 9.1E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 177 3.7E-21 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 Gene3D G3DSA:1.10.1740.10 1 105 5.6E-17 T 29-03-2018 A616_RS07180 37159cf2555cde00f2081a840618b4b6 192 Pfam PF04545 Sigma-70, region 4 129 176 1.4E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 Gene3D G3DSA:3.90.650.10 168 344 1.3E-65 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 SUPERFAMILY SSF55326 4 167 9.87E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 344 48.278 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 1.4E-146 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 Gene3D G3DSA:3.30.1330.10 31 158 2.9E-56 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 SUPERFAMILY SSF56042 169 340 1.27E-61 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 161 1.1E-17 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03570 ed7528d952464fb10228440afa1f22a1 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 340 1.2E-35 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS30545 b5121d433c697c95a487dd4082fe0084 342 Gene3D G3DSA:3.40.50.2300 40 154 3.6E-34 T 29-03-2018 A616_RS30545 b5121d433c697c95a487dd4082fe0084 342 SUPERFAMILY SSF53822 42 264 1.65E-19 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS30545 b5121d433c697c95a487dd4082fe0084 342 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 41 332 2.7E-56 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A616_RS30545 b5121d433c697c95a487dd4082fe0084 342 Gene3D G3DSA:3.40.50.2300 155 340 4.4E-38 T 29-03-2018 A616_RS17795 7fc261ead3f470cd9fef6e4f66936927 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 1.5E-61 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS17795 7fc261ead3f470cd9fef6e4f66936927 261 Gene3D G3DSA:1.10.12.10 222 259 2.3E-11 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS17795 7fc261ead3f470cd9fef6e4f66936927 261 SUPERFAMILY SSF52096 3 261 2.03E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS17795 7fc261ead3f470cd9fef6e4f66936927 261 Gene3D G3DSA:3.90.226.10 3 221 8.2E-71 T 29-03-2018 A616_RS03285 74097596467b85617fa757c723f1ccd4 328 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS03285 74097596467b85617fa757c723f1ccd4 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.4E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS03285 74097596467b85617fa757c723f1ccd4 328 Gene3D G3DSA:3.40.50.300 2 326 1.4E-88 T 29-03-2018 A616_RS03285 74097596467b85617fa757c723f1ccd4 328 SUPERFAMILY SSF52540 5 255 9.58E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03285 74097596467b85617fa757c723f1ccd4 328 SMART SM00382 41 241 1.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03285 74097596467b85617fa757c723f1ccd4 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 3.5E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS03285 74097596467b85617fa757c723f1ccd4 328 Pfam PF00005 ABC transporter 33 183 3.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14655 a1207ea716e6a83ef19ea1e99651eeac 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 9.7E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14655 a1207ea716e6a83ef19ea1e99651eeac 311 SUPERFAMILY SSF161098 94 290 7.85E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14655 a1207ea716e6a83ef19ea1e99651eeac 311 Gene3D G3DSA:1.10.3720.10 2 293 7.7E-47 T 29-03-2018 A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 Pfam PF01476 LysM domain 16 60 1.5E-15 T 29-03-2018 IPR018392 LysM domain A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 SUPERFAMILY SSF54106 14 60 9.81E-12 T 29-03-2018 IPR018392 LysM domain A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 18 61 5.8E-22 T 29-03-2018 IPR014248 Spore coat assembly protein SafA A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 SMART SM00257 15 60 1.1E-15 T 29-03-2018 IPR018392 LysM domain A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 Gene3D G3DSA:3.10.350.10 10 64 1.9E-18 T 29-03-2018 A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 PRINTS PR01217 Proline rich extensin signature 203 220 1.8E-10 T 29-03-2018 A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 PRINTS PR01217 Proline rich extensin signature 153 174 1.8E-10 T 29-03-2018 A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 PRINTS PR01217 Proline rich extensin signature 117 133 1.8E-10 T 29-03-2018 A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 PRINTS PR01217 Proline rich extensin signature 141 153 1.8E-10 T 29-03-2018 A616_RS10620 218ec468ba186ca092d76b73a084b8c5 560 PRINTS PR01217 Proline rich extensin signature 176 192 1.8E-10 T 29-03-2018 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 SUPERFAMILY SSF50249 1 65 3.76E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 SMART SM00357 3 66 8.8E-33 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 PRINTS PR00050 Cold shock protein signature 24 33 1.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 PRINTS PR00050 Cold shock protein signature 39 57 1.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 9.5E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 PIRSF PIRSF002599 1 66 3.6E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS05400 8e1916c1ab0f1b8fd25653d69fedafec 66 Gene3D G3DSA:2.40.50.140 1 66 1.3E-29 T 29-03-2018 A616_RS12700 9e58fd76a9c386776feb0dc19375fba2 255 Pfam PF07486 Cell Wall Hydrolase 156 254 2.1E-27 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A616_RS12700 9e58fd76a9c386776feb0dc19375fba2 255 Pfam PF01471 Putative peptidoglycan binding domain 43 96 3.9E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS12700 9e58fd76a9c386776feb0dc19375fba2 255 SUPERFAMILY SSF47090 35 99 1.57E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS12700 9e58fd76a9c386776feb0dc19375fba2 255 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 31 255 2.4E-94 T 29-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 A616_RS12700 9e58fd76a9c386776feb0dc19375fba2 255 Gene3D G3DSA:1.10.101.10 28 108 1.5E-19 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS08225 64c9ef8ce00481e75049232856038210 191 Pfam PF02525 Flavodoxin-like fold 1 176 1.1E-44 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS08225 64c9ef8ce00481e75049232856038210 191 Gene3D G3DSA:3.40.50.360 1 191 4.1E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS08225 64c9ef8ce00481e75049232856038210 191 SUPERFAMILY SSF52218 1 190 3.88E-56 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 Pfam PF02355 Protein export membrane protein 107 295 7.6E-61 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 12 297 25.237 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 109 283 2.1E-49 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 PRINTS PR01755 Bacterial translocase SecF protein signature 234 249 3.8E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 3.8E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 PRINTS PR01755 Bacterial translocase SecF protein signature 39 54 3.8E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 3.8E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 Gene3D G3DSA:1.20.1640.10 86 304 1.1E-29 T 29-03-2018 A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 SUPERFAMILY SSF82866 108 299 1.44E-36 T 29-03-2018 A616_RS10720 5d4be9a97f07053f8bbe0a11535d93d9 305 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 40 286 1.4E-65 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A616_RS20345 df9b29cbbbd5f938a7e82833b460bc5a 264 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 14 46 - T 29-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 A616_RS20345 df9b29cbbbd5f938a7e82833b460bc5a 264 SUPERFAMILY SSF52151 6 260 1.12E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS20345 df9b29cbbbd5f938a7e82833b460bc5a 264 Pfam PF01734 Patatin-like phospholipase 12 167 5.5E-19 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A616_RS20345 df9b29cbbbd5f938a7e82833b460bc5a 264 Gene3D G3DSA:3.40.1090.10 1 212 1.2E-43 T 29-03-2018 A616_RS05925 19c199f217628b6586b32454e33e466b 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 427 2.6E-169 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A616_RS05925 19c199f217628b6586b32454e33e466b 428 Pfam PF00202 Aminotransferase class-III 36 410 3.4E-66 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS05925 19c199f217628b6586b32454e33e466b 428 SUPERFAMILY SSF53383 2 428 3.74E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS05925 19c199f217628b6586b32454e33e466b 428 Gene3D G3DSA:3.40.640.10 170 315 1.6E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS05925 19c199f217628b6586b32454e33e466b 428 Gene3D G3DSA:3.90.1150.10 1 169 3.3E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS05925 19c199f217628b6586b32454e33e466b 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 93.068 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A616_RS05925 19c199f217628b6586b32454e33e466b 428 Gene3D G3DSA:3.90.1150.10 316 428 4.1E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 686 26.984 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 2.3E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 2.3E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 2.3E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 2.3E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 2.3E-37 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 SUPERFAMILY SSF109604 337 490 4.29E-14 T 29-03-2018 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 Gene3D G3DSA:1.10.730.10 504 680 9.0E-8 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 Pfam PF05746 DALR anticodon binding domain 587 678 5.4E-6 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 686 9.9E-250 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS11670 f30ea2e9758faa71e2119a365687e26c 689 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 555 1.9E-213 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A616_RS04320 6f0afec4775c41a4302eef2d477e96e6 166 Pfam PF14568 SMI1-KNR4 cell-wall 19 161 1.1E-16 T 29-03-2018 A616_RS04320 6f0afec4775c41a4302eef2d477e96e6 166 SUPERFAMILY SSF160631 12 165 1.44E-20 T 29-03-2018 A616_RS04320 6f0afec4775c41a4302eef2d477e96e6 166 SMART SM00860 15 164 2.7E-8 T 29-03-2018 IPR018958 Knr4/Smi1-like domain A616_RS04320 6f0afec4775c41a4302eef2d477e96e6 166 Gene3D G3DSA:3.40.1580.10 6 166 2.9E-22 T 29-03-2018 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Gene3D G3DSA:1.10.10.10 507 602 8.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Pfam PF00072 Response regulator receiver domain 386 496 1.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 373 1.2E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 SUPERFAMILY SSF46894 537 601 9.52E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 SUPERFAMILY SSF55874 252 373 1.26E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 ProSitePatterns PS00622 LuxR-type HTH domain signature. 556 583 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Gene3D G3DSA:3.40.50.2300 383 506 2.3E-36 T 29-03-2018 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Pfam PF07730 Histidine kinase 184 246 7.2E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Pfam PF00196 Bacterial regulatory proteins, luxR family 542 594 7.4E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 SMART SM00448 383 496 1.0E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 SMART SM00421 539 596 3.0E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 542 556 1.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 556 572 1.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 572 584 1.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 Gene3D G3DSA:3.30.565.10 246 382 9.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 SUPERFAMILY SSF52172 383 512 9.68E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS07485 5a25c8d56935cb2085c2b79830c246ba 602 SMART SM00387 286 376 9.8E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS06440 7393093341b3f970fbc589db012998d7 190 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 7 109 7.2E-8 T 29-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 A616_RS06590 0c7c127b15f46847ab6ca2fa52add94c 258 Gene3D G3DSA:3.40.190.10 23 130 4.0E-26 T 29-03-2018 A616_RS06590 0c7c127b15f46847ab6ca2fa52add94c 258 Gene3D G3DSA:3.40.190.10 131 216 2.2E-22 T 29-03-2018 A616_RS06590 0c7c127b15f46847ab6ca2fa52add94c 258 SUPERFAMILY SSF53850 1 254 9.32E-66 T 29-03-2018 A616_RS06590 0c7c127b15f46847ab6ca2fa52add94c 258 SMART SM00062 32 254 6.3E-70 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS06590 0c7c127b15f46847ab6ca2fa52add94c 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 253 1.7E-66 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS26115 9fa313260fdc5f07145bd9486a976ef4 177 Pfam PF00355 Rieske [2Fe-2S] domain 70 155 1.2E-14 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS26115 9fa313260fdc5f07145bd9486a976ef4 177 Gene3D G3DSA:2.102.10.10 59 176 6.7E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS26115 9fa313260fdc5f07145bd9486a976ef4 177 SUPERFAMILY SSF50022 26 167 1.13E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS30535 00b2ba58f2f3ccfe3916eb8deaac7e3f 356 Gene3D G3DSA:1.10.3470.10 5 340 3.8E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS30535 00b2ba58f2f3ccfe3916eb8deaac7e3f 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 333 9.6E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS29680 b9721167a32e371f498670da1b3881f6 632 SUPERFAMILY SSF56235 1 227 9.44E-68 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS29680 b9721167a32e371f498670da1b3881f6 632 Pfam PF13537 Glutamine amidotransferase domain 50 168 5.1E-48 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A616_RS29680 b9721167a32e371f498670da1b3881f6 632 Gene3D G3DSA:3.60.20.10 1 224 1.5E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS29680 b9721167a32e371f498670da1b3881f6 632 PIRSF PIRSF001589 1 632 8.9E-169 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS29680 b9721167a32e371f498670da1b3881f6 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 565 5.4E-154 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS29680 b9721167a32e371f498670da1b3881f6 632 Gene3D G3DSA:3.40.50.620 225 630 9.7E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS29680 b9721167a32e371f498670da1b3881f6 632 SUPERFAMILY SSF52402 484 608 4.75E-69 T 29-03-2018 A616_RS29680 b9721167a32e371f498670da1b3881f6 632 SUPERFAMILY SSF52402 236 387 4.75E-69 T 29-03-2018 A616_RS29680 b9721167a32e371f498670da1b3881f6 632 Pfam PF00733 Asparagine synthase 245 625 6.4E-84 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A616_RS00470 1062ada35377d6c8a961b026ee542ff5 210 Gene3D G3DSA:3.40.50.720 1 210 3.1E-23 T 29-03-2018 A616_RS00470 1062ada35377d6c8a961b026ee542ff5 210 Pfam PF13460 NAD(P)H-binding 8 198 2.7E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS00470 1062ada35377d6c8a961b026ee542ff5 210 SUPERFAMILY SSF51735 1 210 1.66E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 Gene3D G3DSA:1.10.287.470 128 185 1.3E-10 T 29-03-2018 A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 Gene3D G3DSA:3.90.1170.30 17 117 1.3E-6 T 29-03-2018 A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 SUPERFAMILY SSF111369 49 139 2.62E-9 T 29-03-2018 A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 Gene3D G3DSA:2.40.50.100 214 391 0.0021 T 29-03-2018 A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 316 1.2E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 SUPERFAMILY SSF111369 202 326 1.96E-8 T 29-03-2018 A616_RS30285 e9fc5cd09afc4db989872f0b10805f28 410 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 211 403 2.3E-37 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 Gene3D G3DSA:3.40.50.300 10 219 2.9E-61 T 29-03-2018 A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 Pfam PF00270 DEAD/DEAH box helicase 27 192 3.2E-52 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 Gene3D G3DSA:3.40.50.300 220 482 9.4E-49 T 29-03-2018 A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 Pfam PF00271 Helicase conserved C-terminal domain 227 336 8.9E-31 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 SMART SM00490 255 336 1.5E-32 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 SMART SM00487 22 219 3.1E-66 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS24020 db70d45f9b9b1277f94873ed8814c443 496 SUPERFAMILY SSF52540 71 350 9.0E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31405 ee066f762accbe1d4cdba2446f066291 118 Pfam PF00893 Small Multidrug Resistance protein 12 108 1.2E-8 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS31405 ee066f762accbe1d4cdba2446f066291 118 SUPERFAMILY SSF103481 44 116 9.15E-13 T 29-03-2018 A616_RS05325 92157e2718b70183377841b76379cd80 136 SUPERFAMILY SSF54637 2 129 5.15E-36 T 29-03-2018 IPR029069 HotDog domain A616_RS05325 92157e2718b70183377841b76379cd80 136 Pfam PF13279 Thioesterase-like superfamily 9 127 4.8E-22 T 29-03-2018 A616_RS05325 92157e2718b70183377841b76379cd80 136 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 1.3E-22 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A616_RS05325 92157e2718b70183377841b76379cd80 136 PIRSF PIRSF003230 1 134 2.3E-23 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A616_RS05325 92157e2718b70183377841b76379cd80 136 Gene3D G3DSA:3.10.129.10 1 131 3.1E-36 T 29-03-2018 A616_RS08580 8d05705336980b99662228f646ac84fa 180 Gene3D G3DSA:1.10.1740.10 3 82 1.1E-22 T 29-03-2018 A616_RS08580 8d05705336980b99662228f646ac84fa 180 Pfam PF08281 Sigma-70, region 4 110 162 3.4E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08580 8d05705336980b99662228f646ac84fa 180 Pfam PF04542 Sigma-70 region 2 12 79 4.0E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08580 8d05705336980b99662228f646ac84fa 180 Gene3D G3DSA:1.10.10.10 95 179 4.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08580 8d05705336980b99662228f646ac84fa 180 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 34 65 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08580 8d05705336980b99662228f646ac84fa 180 SUPERFAMILY SSF88659 98 166 5.79E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08580 8d05705336980b99662228f646ac84fa 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 164 1.6E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08580 8d05705336980b99662228f646ac84fa 180 SUPERFAMILY SSF88946 11 86 2.16E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 Gene3D G3DSA:3.30.457.10 77 150 1.8E-11 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 Pfam PF07833 Copper amine oxidase N-terminal domain 75 160 3.3E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 Pfam PF08239 Bacterial SH3 domain 186 231 6.7E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 SMART SM00636 263 564 4.2E-7 T 29-03-2018 IPR011583 Chitinase II GO:0008061 A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 SUPERFAMILY SSF51445 284 472 1.44E-43 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 SUPERFAMILY SSF51445 536 571 1.44E-43 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 Gene3D G3DSA:2.40.50.110 163 236 1.2E-7 T 29-03-2018 A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 SMART SM00287 173 236 1.9E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 Pfam PF00704 Glycosyl hydrolases family 18 336 561 4.9E-25 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 Gene3D G3DSA:3.20.20.80 249 577 1.5E-45 T 29-03-2018 A616_RS06005 fb2855fe706b2a2a3e130e30f07dce86 577 SUPERFAMILY SSF55383 76 157 1.28E-12 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS00255 60abefb0499a44d30a830697115337aa 269 Gene3D G3DSA:3.40.720.10 3 263 1.9E-36 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS00255 60abefb0499a44d30a830697115337aa 269 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 7 211 3.5E-13 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A616_RS00255 60abefb0499a44d30a830697115337aa 269 SUPERFAMILY SSF53649 4 257 3.14E-42 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS29645 71d6565af1605aca9d55d0d8f5b003b6 315 TIGRFAM TIGR04399 acc_Sec_SLAP: accessory Sec system S-layer assembly protein 19 313 2.7E-92 T 29-03-2018 IPR030911 Accessory Sec system S-layer assembly protein A616_RS29645 71d6565af1605aca9d55d0d8f5b003b6 315 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 53 177 1.1E-39 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type A616_RS29645 71d6565af1605aca9d55d0d8f5b003b6 315 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 188 311 6.4E-41 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 7.7E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 7.7E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 7.7E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 7.7E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 SMART SM00347 27 127 9.3E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 Gene3D G3DSA:1.10.10.10 3 138 3.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 Pfam PF01047 MarR family 34 92 7.3E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20475 d4499b77b4bc17ec07ce7fb51b6185ba 141 SUPERFAMILY SSF46785 15 139 2.36E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.3E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 SMART SM00448 3 117 6.9E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 Pfam PF00072 Response regulator receiver domain 5 117 1.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 Gene3D G3DSA:3.40.50.2300 2 128 2.3E-33 T 29-03-2018 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 Gene3D G3DSA:1.10.10.10 129 218 1.2E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 SUPERFAMILY SSF46894 148 216 5.44E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.8E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 SMART SM00421 152 209 2.1E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS02370 2faec79fe0711c2d19d802332c4c6de4 218 SUPERFAMILY SSF52172 2 133 2.42E-32 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 2.5E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 Gene3D G3DSA:3.40.50.300 2 320 2.2E-83 T 29-03-2018 A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 320 5.2E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 SUPERFAMILY SSF52540 7 254 3.93E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 SMART SM00382 40 232 3.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04640 75b59db94b6ccf0a9249687b36efa825 320 Pfam PF00005 ABC transporter 32 182 4.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS01765 94fa2a74b7f95826da4aa3350ce61e03 227 Pfam PF00005 ABC transporter 23 169 8.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS01765 94fa2a74b7f95826da4aa3350ce61e03 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS01765 94fa2a74b7f95826da4aa3350ce61e03 227 SUPERFAMILY SSF52540 3 221 1.66E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01765 94fa2a74b7f95826da4aa3350ce61e03 227 Gene3D G3DSA:3.40.50.300 1 225 1.2E-64 T 29-03-2018 A616_RS01765 94fa2a74b7f95826da4aa3350ce61e03 227 SMART SM00382 32 218 4.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15760 cf48066e558c136b8805c4c6a372f9d6 282 SUPERFAMILY SSF55166 82 218 5.49E-21 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS15760 cf48066e558c136b8805c4c6a372f9d6 282 Gene3D G3DSA:3.30.1380.10 75 207 2.0E-20 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS15760 cf48066e558c136b8805c4c6a372f9d6 282 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 93 209 8.2E-21 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A616_RS23725 56773c8235c214165d9031579ca52156 154 Gene3D G3DSA:3.30.530.20 1 152 5.9E-23 T 29-03-2018 IPR023393 START-like domain A616_RS23725 56773c8235c214165d9031579ca52156 154 SUPERFAMILY SSF55961 1 147 3.39E-34 T 29-03-2018 A616_RS23725 56773c8235c214165d9031579ca52156 154 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 144 2.2E-23 T 29-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G A616_RS01830 71ddcc437365549f63cba1746894b104 174 Gene3D G3DSA:1.20.120.80 9 173 4.2E-10 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS01830 71ddcc437365549f63cba1746894b104 174 Pfam PF04238 Protein of unknown function (DUF420) 41 170 9.6E-42 T 29-03-2018 IPR007352 Protein of unknown function DUF420 A616_RS15020 c7637226d91e5943db8e469a926bd456 341 Pfam PF12833 Helix-turn-helix domain 251 327 1.3E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS15020 c7637226d91e5943db8e469a926bd456 341 SMART SM00342 244 326 2.8E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS15020 c7637226d91e5943db8e469a926bd456 341 Gene3D G3DSA:1.10.10.60 277 331 3.7E-12 T 29-03-2018 A616_RS15020 c7637226d91e5943db8e469a926bd456 341 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 20 199 5.0E-26 T 29-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal A616_RS15020 c7637226d91e5943db8e469a926bd456 341 SUPERFAMILY SSF46689 280 330 8.96E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15020 c7637226d91e5943db8e469a926bd456 341 Gene3D G3DSA:1.10.10.60 94 276 2.0E-4 T 29-03-2018 A616_RS32220 7f6a7eae14ad632c3fa8e35a0b2ff3e3 291 SUPERFAMILY SSF50182 123 186 8.5E-16 T 29-03-2018 IPR010920 LSM domain A616_RS32220 7f6a7eae14ad632c3fa8e35a0b2ff3e3 291 Gene3D G3DSA:2.30.30.60 138 187 2.3E-14 T 29-03-2018 A616_RS32220 7f6a7eae14ad632c3fa8e35a0b2ff3e3 291 Pfam PF00924 Mechanosensitive ion channel 79 277 5.4E-44 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A616_RS32220 7f6a7eae14ad632c3fa8e35a0b2ff3e3 291 Gene3D G3DSA:3.30.70.100 188 282 4.0E-16 T 29-03-2018 A616_RS32220 7f6a7eae14ad632c3fa8e35a0b2ff3e3 291 SUPERFAMILY SSF82861 30 121 2.35E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A616_RS32220 7f6a7eae14ad632c3fa8e35a0b2ff3e3 291 SUPERFAMILY SSF82689 188 282 2.62E-15 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A616_RS15225 e7e6440a7b3a5392aae193a00a6ce870 445 SUPERFAMILY SSF53850 63 421 6.96E-82 T 29-03-2018 A616_RS15225 e7e6440a7b3a5392aae193a00a6ce870 445 Gene3D G3DSA:3.40.190.10 55 188 4.3E-10 T 29-03-2018 A616_RS15225 e7e6440a7b3a5392aae193a00a6ce870 445 Gene3D G3DSA:3.40.190.10 189 445 4.9E-46 T 29-03-2018 A616_RS15225 e7e6440a7b3a5392aae193a00a6ce870 445 Pfam PF01547 Bacterial extracellular solute-binding protein 67 358 1.9E-44 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 A616_RS14035 85ad180bdf18ff77680792ea252ef598 348 SUPERFAMILY SSF53448 2 288 1.98E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS14035 85ad180bdf18ff77680792ea252ef598 348 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 338 1.6E-103 T 29-03-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form A616_RS14035 85ad180bdf18ff77680792ea252ef598 348 Gene3D G3DSA:2.160.10.10 243 338 3.4E-10 T 29-03-2018 A616_RS14035 85ad180bdf18ff77680792ea252ef598 348 Gene3D G3DSA:3.90.550.10 1 242 3.2E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS14035 85ad180bdf18ff77680792ea252ef598 348 Pfam PF00483 Nucleotidyl transferase 2 231 2.0E-41 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 Gene3D G3DSA:3.30.420.40 245 309 7.7E-8 T 29-03-2018 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 Pfam PF06723 MreB/Mbl protein 4 327 2.5E-146 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 Gene3D G3DSA:3.90.640.10 189 244 3.6E-27 T 29-03-2018 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 Gene3D G3DSA:3.30.420.40 154 188 3.4E-4 T 29-03-2018 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 SUPERFAMILY SSF53067 143 325 1.35E-48 T 29-03-2018 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 3.8E-135 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 SUPERFAMILY SSF53067 2 141 1.94E-36 T 29-03-2018 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 125 144 3.3E-56 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 3.3E-56 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 3.3E-56 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 3.3E-56 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 180 200 3.3E-56 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A616_RS29800 65f9d578bb83df6ddf7ae28ad2227e33 338 Gene3D G3DSA:3.30.420.40 2 153 2.1E-35 T 29-03-2018 A616_RS12505 8f52519065622b0aef1e9c818f73da21 264 PIRSF PIRSF009141 1 263 1.4E-120 T 29-03-2018 IPR008535 Protein of unknown function DUF817 A616_RS12505 8f52519065622b0aef1e9c818f73da21 264 Pfam PF05675 Protein of unknown function (DUF817) 8 241 1.6E-105 T 29-03-2018 IPR008535 Protein of unknown function DUF817 A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 Gene3D G3DSA:3.40.50.300 5 165 7.0E-5 T 29-03-2018 A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 Gene3D G3DSA:3.40.50.300 750 917 7.4E-8 T 29-03-2018 A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 Pfam PF13558 Putative exonuclease SbcCD, C subunit 842 903 2.6E-6 T 29-03-2018 A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 SUPERFAMILY SSF52540 13 241 5.48E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 SUPERFAMILY SSF52540 753 913 5.48E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 SUPERFAMILY SSF75553 388 556 1.57E-5 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A616_RS28795 d38770163d5f8fb9a7935d278e707fc2 965 Gene3D G3DSA:1.20.5.340 218 354 3.1E-5 T 29-03-2018 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Gene3D G3DSA:1.10.1040.10 229 302 1.9E-21 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 PIRSF PIRSF000124 5 431 2.4E-69 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 SUPERFAMILY SSF51735 6 201 6.13E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Gene3D G3DSA:3.40.50.720 303 323 0.23 T 29-03-2018 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 SMART SM00984 325 421 2.4E-18 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Gene3D G3DSA:1.20.5.170 208 228 2.1E-5 T 29-03-2018 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 418 5.6E-18 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 PIRSF PIRSF500136 1 432 5.0E-109 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Gene3D G3DSA:3.40.50.720 2 206 2.1E-39 T 29-03-2018 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 SUPERFAMILY SSF48179 208 298 1.22E-21 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 417 6.5E-105 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 189 1.8E-38 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Gene3D G3DSA:3.40.50.720 324 418 4.8E-19 T 29-03-2018 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 SUPERFAMILY SSF52413 312 427 5.36E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS09610 cdc8d6cb7f5e12f89d40756cd1b43dda 432 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 298 3.6E-21 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS10550 68f0a5366ccbe1f43d62b53087b00903 491 SMART SM00316 36 114 2.4E-4 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS10550 68f0a5366ccbe1f43d62b53087b00903 491 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 412 6.8E-123 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A616_RS10550 68f0a5366ccbe1f43d62b53087b00903 491 Pfam PF10150 Ribonuclease E/G family 116 387 7.9E-91 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A616_RS10550 68f0a5366ccbe1f43d62b53087b00903 491 SUPERFAMILY SSF50249 38 120 6.39E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS10550 68f0a5366ccbe1f43d62b53087b00903 491 Gene3D G3DSA:2.40.50.140 33 119 5.3E-21 T 29-03-2018 A616_RS18185 584f9980150f8e1adda18b3aa978138c 316 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 1 316 1.4E-146 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS18185 584f9980150f8e1adda18b3aa978138c 316 PIRSF PIRSF000355 1 312 3.0E-85 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18185 584f9980150f8e1adda18b3aa978138c 316 Pfam PF00268 Ribonucleotide reductase, small chain 4 277 6.5E-83 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18185 584f9980150f8e1adda18b3aa978138c 316 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 92 108 - T 29-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18185 584f9980150f8e1adda18b3aa978138c 316 Gene3D G3DSA:1.10.620.20 1 289 2.2E-75 T 29-03-2018 A616_RS18185 584f9980150f8e1adda18b3aa978138c 316 SUPERFAMILY SSF47240 2 316 5.05E-91 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS30740 e4131296216d7d0f539c1c46e356b110 95 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 12 83 5.0E-12 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml A616_RS30740 e4131296216d7d0f539c1c46e356b110 95 Gene3D G3DSA:2.40.50.220 1 94 1.2E-33 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml A616_RS30740 e4131296216d7d0f539c1c46e356b110 95 SUPERFAMILY SSF159133 1 89 3.4E-30 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml A616_RS30740 e4131296216d7d0f539c1c46e356b110 95 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 83 7.8E-30 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml A616_RS20440 e076170ea51fc4657d602f6cc6ba05c2 228 SUPERFAMILY SSF55073 64 207 1.57E-42 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS20440 e076170ea51fc4657d602f6cc6ba05c2 228 Pfam PF00990 Diguanylate cyclase, GGDEF domain 59 206 1.1E-42 T 29-03-2018 IPR000160 GGDEF domain A616_RS20440 e076170ea51fc4657d602f6cc6ba05c2 228 SMART SM00267 48 212 6.5E-58 T 29-03-2018 IPR000160 GGDEF domain A616_RS20440 e076170ea51fc4657d602f6cc6ba05c2 228 Gene3D G3DSA:3.30.70.270 52 219 2.7E-52 T 29-03-2018 A616_RS20440 e076170ea51fc4657d602f6cc6ba05c2 228 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 55 208 8.7E-47 T 29-03-2018 IPR000160 GGDEF domain A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 201 8.7E-90 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 Gene3D G3DSA:3.20.20.70 1 216 3.1E-90 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 214 4.6E-95 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 SUPERFAMILY SSF51366 1 214 4.24E-75 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS20750 e78117236835f0415d30fcc5fd2ac3e2 216 PIRSF PIRSF001461 1 216 3.4E-98 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 6.8E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 Gene3D G3DSA:3.40.50.300 3 319 3.4E-83 T 29-03-2018 A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 3.8E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 Pfam PF00005 ABC transporter 28 178 1.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 SMART SM00382 36 228 1.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01090 cf8269971b1356e0d5bc4bc7eea723f2 319 SUPERFAMILY SSF52540 6 250 8.83E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 228 1.8E-57 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 Gene3D G3DSA:3.40.30.10 238 310 2.0E-14 T 29-03-2018 A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 Gene3D G3DSA:3.40.50.1580 1 233 1.9E-56 T 29-03-2018 A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 SUPERFAMILY SSF53167 1 228 4.06E-67 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 Pfam PF01048 Phosphorylase superfamily 2 228 9.7E-54 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 SUPERFAMILY SSF52833 239 307 2.68E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS22975 8504722554cd18cd04dd6a3a81619ba5 310 Pfam PF00462 Glutaredoxin 239 296 1.0E-11 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A616_RS20420 77e91f1b3c6b2d07e4cb8886c1cde505 265 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 248 6.3E-80 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A616_RS20420 77e91f1b3c6b2d07e4cb8886c1cde505 265 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 130 142 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A616_RS20420 77e91f1b3c6b2d07e4cb8886c1cde505 265 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 254 18.058 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A616_RS20420 77e91f1b3c6b2d07e4cb8886c1cde505 265 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 255 3.9E-76 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 SMART SM00138 3 254 1.7E-100 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 1.2E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 1.2E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 PRINTS PR00996 Glutamate methyltransferase family signature 99 119 1.2E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 1.2E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 1.2E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 PRINTS PR00996 Glutamate methyltransferase family signature 62 74 1.2E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 SUPERFAMILY SSF53335 69 248 4.78E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 Gene3D G3DSA:3.40.50.150 68 256 4.6E-51 T 29-03-2018 A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 Gene3D G3DSA:1.10.155.10 1 67 1.4E-14 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 Pfam PF03705 CheR methyltransferase, all-alpha domain 4 56 2.0E-15 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 Pfam PF01739 CheR methyltransferase, SAM binding domain 69 244 2.5E-58 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A616_RS13785 d65624b4b8168d3c3f654bb8d0037eaa 257 SUPERFAMILY SSF47757 1 68 9.02E-14 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A616_RS13625 afeb01254b31f67fc646bf8a49a739f3 227 Pfam PF12945 Flagellar protein YcgR 5 94 1.9E-17 T 29-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal A616_RS13625 afeb01254b31f67fc646bf8a49a739f3 227 Gene3D G3DSA:2.30.110.10 5 102 3.1E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS13625 afeb01254b31f67fc646bf8a49a739f3 227 Pfam PF07238 PilZ domain 103 214 2.6E-12 T 29-03-2018 IPR009875 PilZ domain GO:0035438 A616_RS13625 afeb01254b31f67fc646bf8a49a739f3 227 SUPERFAMILY SSF141371 103 181 2.79E-5 T 29-03-2018 A616_RS13625 afeb01254b31f67fc646bf8a49a739f3 227 Gene3D G3DSA:2.40.10.220 103 223 1.1E-20 T 29-03-2018 A616_RS30585 7071a7fe0a0c9067e11f06e7dcff8696 395 SUPERFAMILY SSF51419 22 275 2.76E-22 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS30585 7071a7fe0a0c9067e11f06e7dcff8696 395 Gene3D G3DSA:3.20.20.10 23 273 7.9E-36 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS30585 7071a7fe0a0c9067e11f06e7dcff8696 395 Pfam PF01168 Alanine racemase, N-terminal domain 21 266 1.6E-12 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A616_RS31260 2f5ed503958744420771e5eb3b83ca1e 1129 Gene3D G3DSA:3.40.50.1440 33 347 2.5E-22 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS31260 2f5ed503958744420771e5eb3b83ca1e 1129 Pfam PF13809 Tubulin like 35 385 2.1E-81 T 29-03-2018 IPR025904 Tubulin-like A616_RS31260 2f5ed503958744420771e5eb3b83ca1e 1129 Gene3D G3DSA:1.25.40.10 378 1001 6.4E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31260 2f5ed503958744420771e5eb3b83ca1e 1129 SUPERFAMILY SSF52490 34 98 2.88E-7 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS31260 2f5ed503958744420771e5eb3b83ca1e 1129 SUPERFAMILY SSF52490 131 207 2.88E-7 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 ProSitePatterns PS00455 Putative AMP-binding domain signature. 584 595 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF52777 1055 1231 4.22E-46 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF52777 13 160 1.67E-19 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF52777 1237 1485 1.33E-53 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1656 1667 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF56801 1464 2036 1.23E-150 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF52777 167 396 1.22E-25 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.40.50.980 1508 1661 2.9E-50 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00550 Phosphopantetheine attachment site 2027 2086 3.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00550 Phosphopantetheine attachment site 960 1021 5.5E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF56601 2558 2884 3.11E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF47336 2016 2088 6.28E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1538 1940 5.1E-119 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 451 874 8.8E-120 T 29-03-2018 IPR010071 Amino acid adenylation domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.30.559.10 2091 2298 2.0E-28 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.40.710.10 2554 2892 4.5E-67 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.40.50.980 423 588 4.5E-43 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:2.30.38.10 758 840 3.5E-19 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:2.30.38.10 1827 1906 1.4E-21 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2411 2540 5.3E-32 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF13193 AMP-binding enzyme C-terminal domain 1924 1997 7.3E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF13193 AMP-binding enzyme C-terminal domain 858 931 2.5E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF56801 390 971 1.57E-153 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF52777 2288 2539 7.89E-37 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF47336 951 1022 1.31E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.30.300.30 846 963 1.3E-38 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.30.300.30 1911 2029 1.1E-36 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00668 Condensation domain 19 408 3.1E-45 T 29-03-2018 IPR001242 Condensation domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00668 Condensation domain 1049 1495 1.3E-115 T 29-03-2018 IPR001242 Condensation domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00668 Condensation domain 2101 2542 1.6E-93 T 29-03-2018 IPR001242 Condensation domain A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:1.10.1200.10 2030 2090 6.9E-15 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:1.10.1200.10 964 1029 1.3E-22 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2048 2063 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.30.559.10 1034 1240 7.5E-37 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.30.559.10 5 171 4.7E-15 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00501 AMP-binding enzyme 1517 1916 5.5E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00501 AMP-binding enzyme 431 850 5.1E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.40.50.980 589 749 1.0E-36 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Gene3D G3DSA:3.40.50.980 1662 1826 2.9E-30 T 29-03-2018 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 Pfam PF00144 Beta-lactamase 2570 2883 6.7E-55 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SMART SM00823 Phosphopantetheine attachment site 958 1027 0.0065 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SMART SM00823 Phosphopantetheine attachment site 2021 2092 0.44 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 A616_RS28660 eb2b59939750f620bc18c6d9b6fd4ae3 2902 SUPERFAMILY SSF52777 2097 2277 7.0E-35 T 29-03-2018 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 Pfam PF00196 Bacterial regulatory proteins, luxR family 825 879 1.7E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 SUPERFAMILY SSF48452 459 781 9.11E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 ProSitePatterns PS00622 LuxR-type HTH domain signature. 840 867 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 826 840 1.9E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 840 856 1.9E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 856 868 1.9E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 Gene3D G3DSA:3.40.50.300 20 343 2.2E-6 T 29-03-2018 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 SUPERFAMILY SSF46894 818 886 1.19E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 SUPERFAMILY SSF52540 13 232 4.09E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 SMART SM00421 823 880 1.1E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 Gene3D G3DSA:1.10.10.10 796 884 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08330 6f22869f43402c7911a139aae4f742f5 886 Gene3D G3DSA:1.25.40.10 456 795 5.9E-33 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 SUPERFAMILY SSF46955 2 116 4.76E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.2E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 Gene3D G3DSA:1.10.1660.10 56 120 3.4E-11 T 29-03-2018 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 Pfam PF13411 MerR HTH family regulatory protein 2 68 2.6E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 SMART SM00422 1 69 2.3E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS17635 c531e397a03c3b93c65ad10f5070966f 121 Gene3D G3DSA:1.10.1660.10 1 55 4.7E-18 T 29-03-2018 A616_RS01260 62630767e4aebe558893371afe7e061b 228 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 222 42.618 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A616_RS01260 62630767e4aebe558893371afe7e061b 228 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 1.5E-73 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A616_RS01260 62630767e4aebe558893371afe7e061b 228 SUPERFAMILY SSF53448 4 222 3.83E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS01260 62630767e4aebe558893371afe7e061b 228 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 221 2.7E-78 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A616_RS01260 62630767e4aebe558893371afe7e061b 228 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 99 106 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A616_RS01260 62630767e4aebe558893371afe7e061b 228 Gene3D G3DSA:3.90.550.10 2 228 1.4E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 Gene3D G3DSA:3.40.50.10320 50 351 1.0E-27 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 Gene3D G3DSA:3.40.50.880 611 841 5.7E-16 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 403 469 3.6E-16 T 29-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 SUPERFAMILY SSF52317 642 839 4.81E-14 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 Pfam PF02585 GlcNAc-PI de-N-acetylase 56 193 2.7E-14 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 SUPERFAMILY SSF102588 53 261 1.31E-29 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 Gene3D G3DSA:2.60.40.10 387 495 1.5E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS24955 e3e6fccb471c88024a0bd634a459135b 843 Gene3D G3DSA:2.60.40.10 505 606 1.2E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 208 412 1.0E-40 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 Gene3D G3DSA:2.40.50.100 223 388 1.0E-4 T 29-03-2018 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 Gene3D G3DSA:2.40.50.100 69 134 1.8E-14 T 29-03-2018 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 SUPERFAMILY SSF111369 202 335 1.7E-9 T 29-03-2018 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 SUPERFAMILY SSF111369 58 146 5.75E-11 T 29-03-2018 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 Pfam PF13533 Biotin-lipoyl like 70 117 1.6E-12 T 29-03-2018 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 Gene3D G3DSA:1.10.287.470 137 194 5.0E-11 T 29-03-2018 A616_RS09035 6e4bee33d735dd395cdfad731c40c259 418 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 181 325 2.8E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 42.97 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 Gene3D G3DSA:3.90.226.10 2 193 1.9E-49 T 29-03-2018 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 1.4E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 1.4E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 1.4E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 1.4E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 1.4E-51 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 SUPERFAMILY SSF52096 10 191 4.26E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 2.9E-96 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS02485 9010603a887d10e6737a851f5ca7e9eb 193 Pfam PF00574 Clp protease 14 192 1.0E-83 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A616_RS11550 f0f3549d0224b1cd8efce7e732bc1b79 621 Pfam PF06276 Ferric iron reductase FhuF-like transporter 426 595 9.8E-32 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain A616_RS11550 f0f3549d0224b1cd8efce7e732bc1b79 621 Pfam PF04183 IucA / IucC family 158 406 5.7E-69 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:3.30.56.50 65 87 0.0061 T 29-03-2018 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:3.30.56.50 122 145 0.0019 T 29-03-2018 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:1.10.3910.10 88 121 0.04 T 29-03-2018 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:1.10.3910.10 165 197 3.5E-5 T 29-03-2018 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:1.10.3910.10 200 233 6.0E-5 T 29-03-2018 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:1.10.3910.10 40 64 3.8E-4 T 29-03-2018 A616_RS30775 0822307edf34de74db81f87a9de8120d 289 Gene3D G3DSA:1.10.3910.10 240 272 7.0E-5 T 29-03-2018 A616_RS16355 441a6ad3f68086d26f8d4a6ae0298c89 271 SMART SM00954 53 180 6.4E-39 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 A616_RS16355 441a6ad3f68086d26f8d4a6ae0298c89 271 SUPERFAMILY SSF81301 15 210 4.74E-50 T 29-03-2018 A616_RS16355 441a6ad3f68086d26f8d4a6ae0298c89 271 Gene3D G3DSA:3.30.460.10 10 161 5.2E-35 T 29-03-2018 A616_RS16355 441a6ad3f68086d26f8d4a6ae0298c89 271 Gene3D G3DSA:1.10.287.860 163 211 6.4E-13 T 29-03-2018 A616_RS16355 441a6ad3f68086d26f8d4a6ae0298c89 271 Pfam PF04607 Region found in RelA / SpoT proteins 53 178 5.7E-34 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 A616_RS31520 aa78b98c2e59c8c52b0c614d510b119e 529 Gene3D G3DSA:3.40.640.10 128 375 3.2E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS31520 aa78b98c2e59c8c52b0c614d510b119e 529 Gene3D G3DSA:3.90.1150.10 376 504 6.5E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS31520 aa78b98c2e59c8c52b0c614d510b119e 529 Pfam PF00266 Aminotransferase class-V 190 305 3.2E-6 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS31520 aa78b98c2e59c8c52b0c614d510b119e 529 SUPERFAMILY SSF53383 54 507 5.09E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS06245 f76900e1a522d70a6631ad0428a473d2 160 Pfam PF05866 Endodeoxyribonuclease RusA 29 133 1.7E-7 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 A616_RS06245 f76900e1a522d70a6631ad0428a473d2 160 SUPERFAMILY SSF103084 28 133 7.45E-13 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 A616_RS06245 f76900e1a522d70a6631ad0428a473d2 160 Gene3D G3DSA:3.30.1330.70 7 134 1.3E-9 T 29-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 SMART SM00487 2 187 4.7E-18 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 SUPERFAMILY SSF52540 18 341 2.65E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 Gene3D G3DSA:3.40.50.300 181 351 4.1E-50 T 29-03-2018 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 Pfam PF00270 DEAD/DEAH box helicase 14 165 6.2E-8 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 Pfam PF08482 ATP-dependent helicase C-terminal 689 821 2.9E-54 T 29-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 833 0.0 T 29-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 Gene3D G3DSA:3.40.50.300 3 163 1.7E-24 T 29-03-2018 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 Pfam PF04408 Helicase associated domain (HA2) 391 471 1.5E-11 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 PIRSF PIRSF005496 1 834 0.0 T 29-03-2018 A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 Pfam PF00271 Helicase conserved C-terminal domain 205 329 4.5E-17 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 SMART SM00490 227 330 7.9E-18 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS08700 bae0b2bab53a8d1bc2e57a9ee6ffcdd8 834 SMART SM00847 390 484 1.8E-17 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 Gene3D G3DSA:1.10.10.10 1 78 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 SUPERFAMILY SSF53850 92 290 4.16E-25 T 29-03-2018 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 Gene3D G3DSA:3.40.190.10 79 168 4.7E-5 T 29-03-2018 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 Pfam PF03466 LysR substrate binding domain 94 289 1.1E-21 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 SUPERFAMILY SSF46785 2 83 6.42E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 Gene3D G3DSA:3.40.190.10 169 261 4.2E-14 T 29-03-2018 A616_RS31860 e8e62f20c27bf0b52965b141be53861e 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.6E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 SUPERFAMILY SSF52518 2 204 5.4E-74 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.3E-44 T 29-03-2018 IPR033248 Transketolase, C-terminal domain A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 Gene3D G3DSA:3.40.50.920 195 326 6.9E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 SUPERFAMILY SSF52922 188 326 1.11E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 7.8E-52 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 SMART SM00861 4 179 6.9E-72 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A616_RS13280 3cc99a94a52ac09b3d90d3d097939a7c 327 Gene3D G3DSA:3.40.50.970 2 194 3.6E-74 T 29-03-2018 A616_RS08360 e31a4f04461dca48fb95d4b51ec348b8 285 Gene3D G3DSA:3.20.20.140 1 279 1.2E-36 T 29-03-2018 A616_RS08360 e31a4f04461dca48fb95d4b51ec348b8 285 SUPERFAMILY SSF51556 1 278 2.95E-40 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS08360 e31a4f04461dca48fb95d4b51ec348b8 285 Pfam PF04909 Amidohydrolase 75 278 9.0E-27 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.6E-9 T 29-03-2018 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.6E-9 T 29-03-2018 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 2.6E-9 T 29-03-2018 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 2.6E-9 T 29-03-2018 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 Gene3D G3DSA:3.50.50.60 136 169 0.22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 Gene3D G3DSA:3.50.50.60 170 336 1.4E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 Gene3D G3DSA:3.50.50.60 4 135 2.5E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 SUPERFAMILY SSF51905 1 119 5.46E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 SUPERFAMILY SSF51905 216 336 5.46E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 SUPERFAMILY SSF51905 157 175 5.46E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS28275 7dadb703f9917d003218ca8c1049b8c1 390 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 322 6.2E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS24865 f82ad1e65a30c02c9402292fab2516bd 150 Gene3D G3DSA:3.40.140.10 1 150 1.8E-34 T 29-03-2018 A616_RS24865 f82ad1e65a30c02c9402292fab2516bd 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 98 2.0E-23 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A616_RS24865 f82ad1e65a30c02c9402292fab2516bd 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 87 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A616_RS24865 f82ad1e65a30c02c9402292fab2516bd 150 SUPERFAMILY SSF53927 2 147 1.35E-38 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 SMART SM00345 16 75 1.0E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 Pfam PF00155 Aminotransferase class I and II 117 468 2.7E-34 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 SUPERFAMILY SSF53383 103 472 3.67E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS24150 9bd4030c5801262743d93addd2731bab 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 4.6E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 Gene3D G3DSA:3.40.640.10 133 378 1.8E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 4.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 4.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS24150 9bd4030c5801262743d93addd2731bab 479 SUPERFAMILY SSF46785 7 77 1.32E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24150 9bd4030c5801262743d93addd2731bab 479 Gene3D G3DSA:1.10.10.10 1 77 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24150 9bd4030c5801262743d93addd2731bab 479 Gene3D G3DSA:3.90.1150.10 379 476 3.5E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 Gene3D G3DSA:3.40.50.300 1 317 1.4E-78 T 29-03-2018 A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 Pfam PF00005 ABC transporter 25 180 2.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 SUPERFAMILY SSF52540 5 251 4.72E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 315 1.5E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 SMART SM00382 33 238 2.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12790 f45b376bf496e323d1873186c3dc1a80 318 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 296 6.3E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS10010 e635b7ff901c7c7f7be81ba3eeed0e9c 98 Gene3D G3DSA:3.30.70.20 8 90 2.8E-6 T 29-03-2018 A616_RS10010 e635b7ff901c7c7f7be81ba3eeed0e9c 98 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS10010 e635b7ff901c7c7f7be81ba3eeed0e9c 98 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 20 92 2.9E-10 T 29-03-2018 A616_RS10010 e635b7ff901c7c7f7be81ba3eeed0e9c 98 SUPERFAMILY SSF54862 37 96 4.89E-17 T 29-03-2018 A616_RS10010 e635b7ff901c7c7f7be81ba3eeed0e9c 98 PIRSF PIRSF036548 5 98 6.6E-21 T 29-03-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 A616_RS11510 bd86105bde7d4d8ccfcff91655e58371 221 Pfam PF04172 LrgB-like family 11 216 3.6E-62 T 29-03-2018 IPR007300 CidB/LrgB family A616_RS25635 cd67447b82c668b5b7629f01ae87e506 315 SUPERFAMILY SSF56112 16 270 1.25E-33 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS25635 cd67447b82c668b5b7629f01ae87e506 315 Pfam PF01636 Phosphotransferase enzyme family 42 225 2.1E-29 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS25635 cd67447b82c668b5b7629f01ae87e506 315 Gene3D G3DSA:3.90.1200.10 100 292 2.4E-20 T 29-03-2018 A616_RS25635 cd67447b82c668b5b7629f01ae87e506 315 Gene3D G3DSA:3.30.200.20 3 99 1.7E-7 T 29-03-2018 A616_RS32005 199dbc12201fbda3ea794f8e2b17377b 456 Pfam PF08031 Berberine and berberine like 409 452 5.5E-21 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 A616_RS32005 199dbc12201fbda3ea794f8e2b17377b 456 Gene3D G3DSA:3.30.43.10 14 92 1.2E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A616_RS32005 199dbc12201fbda3ea794f8e2b17377b 456 Pfam PF01565 FAD binding domain 39 170 4.9E-31 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A616_RS32005 199dbc12201fbda3ea794f8e2b17377b 456 Gene3D G3DSA:3.30.465.10 93 236 3.8E-31 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS32005 199dbc12201fbda3ea794f8e2b17377b 456 SUPERFAMILY SSF56176 12 209 2.2E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 PRINTS PR00173 Glutamate-aspartate symporter signature 93 113 1.6E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 1.6E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 PRINTS PR00173 Glutamate-aspartate symporter signature 260 282 1.6E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 Gene3D G3DSA:1.20.1250.20 216 417 7.9E-18 T 29-03-2018 A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 SUPERFAMILY SSF103473 6 406 6.15E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 Gene3D G3DSA:1.20.1250.20 1 194 5.7E-22 T 29-03-2018 A616_RS22790 6b22bbb5251e7a01ee45a495e5e824b4 418 Pfam PF05977 Transmembrane secretion effector 6 410 7.6E-33 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS09910 b3e292f4aa5ae02d7714e87dca2268c0 426 SUPERFAMILY SSF53850 17 424 3.11E-91 T 29-03-2018 A616_RS09910 b3e292f4aa5ae02d7714e87dca2268c0 426 Gene3D G3DSA:3.40.190.10 170 355 7.5E-48 T 29-03-2018 A616_RS09910 b3e292f4aa5ae02d7714e87dca2268c0 426 Gene3D G3DSA:3.40.190.10 41 169 8.3E-32 T 29-03-2018 A616_RS09910 b3e292f4aa5ae02d7714e87dca2268c0 426 Pfam PF13416 Bacterial extracellular solute-binding protein 58 357 6.4E-43 T 29-03-2018 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 Gene3D G3DSA:1.10.520.20 2 106 1.8E-27 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 SUPERFAMILY SSF47928 3 105 1.31E-25 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 Pfam PF00213 ATP synthase delta (OSCP) subunit 5 173 9.9E-53 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 175 18.656 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 PRINTS PR00125 ATP synthase delta subunit signature 135 150 3.6E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 PRINTS PR00125 ATP synthase delta subunit signature 5 24 3.6E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 PRINTS PR00125 ATP synthase delta subunit signature 85 99 3.6E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 PRINTS PR00125 ATP synthase delta subunit signature 74 85 3.6E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 PRINTS PR00125 ATP synthase delta subunit signature 150 168 3.6E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29915 99843899c9c1c566673508f47a16d72f 175 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 5 173 4.3E-46 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS16360 7cd30a31be41c596bfd8deea01cafaef 291 Pfam PF01551 Peptidase family M23 185 279 2.0E-31 T 29-03-2018 IPR016047 Peptidase M23 A616_RS16360 7cd30a31be41c596bfd8deea01cafaef 291 SUPERFAMILY SSF51261 122 282 9.94E-50 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS16360 7cd30a31be41c596bfd8deea01cafaef 291 Gene3D G3DSA:2.60.40.1590 45 127 3.8E-11 T 29-03-2018 A616_RS16360 7cd30a31be41c596bfd8deea01cafaef 291 Gene3D G3DSA:2.70.70.10 128 287 2.1E-43 T 29-03-2018 A616_RS28915 e88dd537918103f6a2cdb3fc08239734 370 Gene3D G3DSA:3.30.930.10 46 367 5.7E-19 T 29-03-2018 A616_RS28915 e88dd537918103f6a2cdb3fc08239734 370 SUPERFAMILY SSF55681 186 362 3.11E-17 T 29-03-2018 A616_RS28915 e88dd537918103f6a2cdb3fc08239734 370 SUPERFAMILY SSF55681 108 159 3.11E-17 T 29-03-2018 A616_RS28915 e88dd537918103f6a2cdb3fc08239734 370 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 217 358 7.3E-8 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 Gene3D G3DSA:3.40.1190.10 99 307 5.2E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 Gene3D G3DSA:3.40.50.720 2 98 2.5E-17 T 29-03-2018 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 SUPERFAMILY SSF53623 100 307 3.82E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 377 6.0E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 SUPERFAMILY SSF53244 309 449 1.83E-43 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 Gene3D G3DSA:3.90.190.20 314 448 8.6E-38 T 29-03-2018 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 SUPERFAMILY SSF51984 3 97 2.75E-17 T 29-03-2018 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 447 4.2E-130 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 Pfam PF08245 Mur ligase middle domain 114 289 5.2E-27 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A616_RS21305 d948a065780ba9cc1ed18b298764d82a 454 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 449 34.941 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 Gene3D G3DSA:3.40.50.970 1 182 1.5E-44 T 29-03-2018 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 Gene3D G3DSA:3.40.50.970 338 536 2.0E-41 T 29-03-2018 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 377 522 1.7E-34 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 SUPERFAMILY SSF52518 355 529 6.27E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 3.9E-45 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 SUPERFAMILY SSF52518 1 177 9.82E-43 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 188 298 1.5E-20 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 Gene3D G3DSA:3.40.50.1220 183 337 1.6E-27 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS12705 013ef8bcbe3741155ff680a0d6c7a5c6 542 SUPERFAMILY SSF52467 154 340 6.16E-29 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS14495 6e7ed467c47b5cb11d36b6af7f99e048 429 SUPERFAMILY SSF53474 69 427 9.92E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS14495 6e7ed467c47b5cb11d36b6af7f99e048 429 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 208 425 1.2E-47 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal A616_RS14495 6e7ed467c47b5cb11d36b6af7f99e048 429 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 16 143 1.9E-31 T 29-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase A616_RS14495 6e7ed467c47b5cb11d36b6af7f99e048 429 Gene3D G3DSA:3.40.50.1820 134 429 1.8E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS14495 6e7ed467c47b5cb11d36b6af7f99e048 429 PIRSF PIRSF016521 1 428 4.4E-107 T 29-03-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 Gene3D G3DSA:3.40.640.10 168 313 6.6E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 SUPERFAMILY SSF53383 1 425 3.42E-138 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 Gene3D G3DSA:3.90.1150.10 1 164 2.2E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 Gene3D G3DSA:3.90.1150.10 314 428 3.7E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 427 107.053 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 425 1.5E-198 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A616_RS10355 b1c1ae95a4cffcea737fd64bf3d80422 429 Pfam PF00202 Aminotransferase class-III 35 419 8.8E-81 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 9 71 7.4E-13 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 139 7.2E-12 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Pfam PF00403 Heavy-metal-associated domain 78 138 3.2E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Pfam PF00403 Heavy-metal-associated domain 9 69 3.4E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 272 783 5.3E-94 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 231 801 4.8E-203 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 349 363 1.4E-28 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 501 515 1.4E-28 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 646 656 1.4E-28 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 722 734 1.4E-28 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 624 635 1.4E-28 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 699 718 1.4E-28 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Gene3D G3DSA:3.40.50.1000 625 765 9.2E-45 T 29-03-2018 IPR023214 HAD-like domain A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 90 104 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 289 307 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 119 139 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 269 288 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 422 436 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 216 235 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 676 693 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00943 Copper-transporting ATPase signature 484 499 5.6E-21 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Gene3D G3DSA:3.40.1110.10 517 624 3.4E-32 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF55008 75 144 1.7E-21 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 503 509 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 80 109 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Gene3D G3DSA:3.30.70.100 74 151 2.5E-24 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Gene3D G3DSA:3.30.70.100 4 73 5.4E-20 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF55008 3 72 4.84E-20 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Pfam PF00702 haloacid dehalogenase-like hydrolase 498 713 2.3E-47 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF81653 303 399 7.45E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 802 3.6E-188 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Pfam PF00122 E1-E2 ATPase 300 480 9.8E-60 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 Gene3D G3DSA:1.20.1110.10 260 516 9.0E-46 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 214 239 1.4E-12 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 33 56 1.4E-12 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 7 32 1.4E-12 T 29-03-2018 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF56784 499 519 1.21E-64 T 29-03-2018 IPR023214 HAD-like domain A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF56784 557 799 1.21E-64 T 29-03-2018 IPR023214 HAD-like domain A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF81665 267 303 3.27E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF81665 400 495 3.27E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS02215 2b683349ce6bd4c25aa0ac973303910e 806 SUPERFAMILY SSF81665 748 778 3.27E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS26235 a3cb4f6bd9df7d88b0914de053d5b9d4 124 Gene3D G3DSA:1.10.3450.10 2 115 2.8E-29 T 29-03-2018 IPR023203 TTHA0068-like domain A616_RS26235 a3cb4f6bd9df7d88b0914de053d5b9d4 124 Pfam PF03745 Domain of unknown function (DUF309) 8 61 6.6E-22 T 29-03-2018 IPR005500 Protein of unknown function DUF309 A616_RS26235 a3cb4f6bd9df7d88b0914de053d5b9d4 124 SUPERFAMILY SSF140663 3 107 1.29E-33 T 29-03-2018 IPR023203 TTHA0068-like domain A616_RS15250 339a9bd400cdeb11392679434ba3baef 355 Gene3D G3DSA:3.40.50.970 1 344 1.6E-93 T 29-03-2018 A616_RS15250 339a9bd400cdeb11392679434ba3baef 355 SUPERFAMILY SSF52518 21 344 4.15E-104 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS15250 339a9bd400cdeb11392679434ba3baef 355 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 4 343 9.9E-144 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A616_RS15250 339a9bd400cdeb11392679434ba3baef 355 Pfam PF00676 Dehydrogenase E1 component 32 322 1.6E-91 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A616_RS20725 77747ef2e789c7181f7504a2a0445c8e 219 SUPERFAMILY SSF161098 13 201 5.76E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS20725 77747ef2e789c7181f7504a2a0445c8e 219 Gene3D G3DSA:1.10.3720.10 2 219 5.1E-41 T 29-03-2018 A616_RS20725 77747ef2e789c7181f7504a2a0445c8e 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.0E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS20725 77747ef2e789c7181f7504a2a0445c8e 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 9.6E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS19885 0441ad170c265d8cbf75ae57362cd066 174 Gene3D G3DSA:1.10.10.10 116 158 3.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19885 0441ad170c265d8cbf75ae57362cd066 174 Gene3D G3DSA:1.20.58.130 28 100 6.3E-5 T 29-03-2018 A616_RS13130 32bb7d7832fc10ae922b218a0dc19313 460 Pfam PF13742 OB-fold nucleic acid binding domain 7 102 1.0E-29 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A616_RS13130 32bb7d7832fc10ae922b218a0dc19313 460 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 349 2.9E-142 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A616_RS13130 32bb7d7832fc10ae922b218a0dc19313 460 Gene3D G3DSA:3.90.226.10 170 361 2.8E-5 T 29-03-2018 A616_RS13130 32bb7d7832fc10ae922b218a0dc19313 460 Pfam PF02601 Exonuclease VII, large subunit 125 438 4.6E-103 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A616_RS13130 32bb7d7832fc10ae922b218a0dc19313 460 Gene3D G3DSA:2.40.50.140 3 103 6.8E-8 T 29-03-2018 A616_RS13130 32bb7d7832fc10ae922b218a0dc19313 460 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 441 30.531 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 1.0E-5 T 29-03-2018 A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 SUPERFAMILY SSF51735 6 245 1.98E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 Gene3D G3DSA:3.40.50.720 1 247 6.0E-69 T 29-03-2018 A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 2.0E-59 T 29-03-2018 A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS17630 b4fe47cfa251a70f46e5a27e52d0a0ad 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS01385 f8167e31b34949da785697f5e732f214 128 SUPERFAMILY SSF46458 7 125 1.15E-38 T 29-03-2018 IPR009050 Globin-like A616_RS01385 f8167e31b34949da785697f5e732f214 128 Pfam PF01152 Bacterial-like globin 9 123 7.2E-34 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 A616_RS01385 f8167e31b34949da785697f5e732f214 128 Gene3D G3DSA:1.10.490.10 3 128 8.4E-34 T 29-03-2018 A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 Pfam PF00005 ABC transporter 21 169 2.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 Gene3D G3DSA:3.30.70.260 255 341 1.3E-20 T 29-03-2018 A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 SMART SM00382 30 218 2.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 Pfam PF09383 NIL domain 266 335 2.9E-16 T 29-03-2018 IPR018449 NIL domain A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 SUPERFAMILY SSF52540 1 240 1.6E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 SMART SM00930 263 338 3.2E-17 T 29-03-2018 IPR018449 NIL domain A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 SUPERFAMILY SSF55021 249 338 2.17E-16 T 29-03-2018 A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 Gene3D G3DSA:3.40.50.300 1 254 9.3E-78 T 29-03-2018 A616_RS31150 2bdfe32362151d34c032417b89393a8e 345 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS18490 fd76f13587a61b5075e86d5b39ba80c2 78 Gene3D G3DSA:1.10.1200.10 1 75 4.4E-9 T 29-03-2018 A616_RS18490 fd76f13587a61b5075e86d5b39ba80c2 78 SUPERFAMILY SSF47336 23 76 5.76E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS18490 fd76f13587a61b5075e86d5b39ba80c2 78 Pfam PF00550 Phosphopantetheine attachment site 29 69 2.8E-5 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 SUPERFAMILY SSF48498 82 191 9.34E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 SUPERFAMILY SSF46689 4 73 9.98E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 Gene3D G3DSA:1.10.357.10 4 194 7.8E-31 T 29-03-2018 A616_RS01915 c67d30c4bece11d6d59a5c67595446cd 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 641 96.218 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Pfam PF00204 DNA gyrase B 228 397 1.0E-64 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 SUPERFAMILY SSF54211 228 399 1.18E-62 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 SMART SM00433 40 634 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 118 132 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 511 528 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 275 288 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 531 543 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 493 509 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 573 589 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR00418 DNA topoisomerase II family signature 427 441 1.9E-72 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 SUPERFAMILY SSF55874 10 218 5.5E-73 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Gene3D G3DSA:3.40.50.670 407 638 7.2E-105 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 SMART SM00387 36 180 6.8E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 570 630 3.6E-30 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Gene3D G3DSA:3.30.230.10 228 399 2.2E-66 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 179 5.9E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 381 401 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 367 381 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 610 626 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 319 335 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 477 486 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 594 606 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 PRINTS PR01159 DNA gyrase subunit B signature 227 249 1.6E-78 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 SUPERFAMILY SSF56719 401 635 2.17E-92 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 641 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Pfam PF01751 Toprim domain 426 537 4.0E-18 T 29-03-2018 IPR006171 TOPRIM domain A616_RS00030 9b8e5f36d47fa235751706e529e4395b 641 Gene3D G3DSA:3.30.565.10 23 227 1.0E-76 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18820 8966589eaf79b9e457d6b40cc11d0404 427 Gene3D G3DSA:1.20.1250.20 10 206 4.1E-20 T 29-03-2018 A616_RS18820 8966589eaf79b9e457d6b40cc11d0404 427 Gene3D G3DSA:1.20.1250.20 213 421 1.5E-12 T 29-03-2018 A616_RS18820 8966589eaf79b9e457d6b40cc11d0404 427 Pfam PF07690 Major Facilitator Superfamily 16 364 1.8E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS18820 8966589eaf79b9e457d6b40cc11d0404 427 SUPERFAMILY SSF103473 11 407 1.44E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 SUPERFAMILY SSF54506 139 273 1.31E-29 T 29-03-2018 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 Gene3D G3DSA:3.10.310.10 3 128 3.9E-40 T 29-03-2018 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 Pfam PF01678 Diaminopimelate epimerase 149 265 2.9E-15 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 Pfam PF01678 Diaminopimelate epimerase 8 120 1.4E-27 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 6 276 31.175 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 7 274 1.2E-72 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 69 83 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 SUPERFAMILY SSF54506 6 125 6.12E-36 T 29-03-2018 A616_RS16045 546a56dd7cf86b39734f783d45efd5bd 280 Gene3D G3DSA:3.10.310.10 129 256 4.6E-28 T 29-03-2018 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 SUPERFAMILY SSF46689 197 245 1.88E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 Pfam PF00072 Response regulator receiver domain 4 116 6.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 Pfam PF12833 Helix-turn-helix domain 167 244 3.7E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 198 240 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 244 3.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 213 228 3.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 Gene3D G3DSA:1.10.10.60 144 193 3.6E-15 T 29-03-2018 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 Gene3D G3DSA:3.40.50.2300 1 143 5.2E-34 T 29-03-2018 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 SMART SM00448 2 116 8.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 Gene3D G3DSA:1.10.10.60 194 251 1.2E-16 T 29-03-2018 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 SUPERFAMILY SSF52172 1 132 1.24E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 SUPERFAMILY SSF46689 145 195 1.88E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25545 fb96a4e2cc42c0071a11c816e616af02 252 SMART SM00342 161 244 6.3E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS02620 76a5f9e0fde240254c6cb50c3e8e5917 217 Gene3D G3DSA:3.40.30.10 43 216 3.9E-36 T 29-03-2018 A616_RS02620 76a5f9e0fde240254c6cb50c3e8e5917 217 SUPERFAMILY SSF52833 56 215 8.81E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS02620 76a5f9e0fde240254c6cb50c3e8e5917 217 Pfam PF02630 SCO1/SenC 59 197 4.2E-26 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 SMART SM00862 154 231 8.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 231 5.2E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 Gene3D G3DSA:3.40.50.2300 1 125 3.4E-34 T 29-03-2018 A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 Pfam PF00072 Response regulator receiver domain 7 116 2.6E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 Gene3D G3DSA:1.10.10.10 126 238 3.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 SUPERFAMILY SSF46894 130 232 2.83E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 SUPERFAMILY SSF52172 3 125 1.57E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS05360 2831d9d1ec16d47c1e0d2afb2aa3a272 238 SMART SM00448 5 116 1.6E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02995 035d82b62dce89bb0fc4250b7889bfcc 333 Gene3D G3DSA:3.40.980.10 140 316 4.7E-38 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02995 035d82b62dce89bb0fc4250b7889bfcc 333 Pfam PF00994 Probable molybdopterin binding domain 182 310 6.6E-21 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02995 035d82b62dce89bb0fc4250b7889bfcc 333 SMART SM00852 181 311 1.4E-22 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS02995 035d82b62dce89bb0fc4250b7889bfcc 333 SUPERFAMILY SSF53218 179 317 3.93E-31 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS07275 84d98e8e7edd7ccebd5ed7db4cc8e497 367 SUPERFAMILY SSF53474 64 363 5.45E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS07275 84d98e8e7edd7ccebd5ed7db4cc8e497 367 Gene3D G3DSA:3.40.50.1820 46 367 8.9E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS07275 84d98e8e7edd7ccebd5ed7db4cc8e497 367 Pfam PF12146 Serine aminopeptidase, S33 107 349 1.1E-17 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 A616_RS31705 794d0daf5dcfb5ddc34db7989926475b 420 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 193 410 2.8E-31 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS31705 794d0daf5dcfb5ddc34db7989926475b 420 Gene3D G3DSA:2.40.50.100 213 412 8.6E-6 T 29-03-2018 A616_RS31705 794d0daf5dcfb5ddc34db7989926475b 420 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 46 300 1.3E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS31705 794d0daf5dcfb5ddc34db7989926475b 420 Gene3D G3DSA:1.10.287.470 142 185 6.3E-8 T 29-03-2018 A616_RS31705 794d0daf5dcfb5ddc34db7989926475b 420 Gene3D G3DSA:2.40.50.100 58 141 1.4E-9 T 29-03-2018 A616_RS25005 0ccfd69904934279c7a87a0f468b3f81 349 PIRSF PIRSF001439 1 349 1.4E-79 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS25005 0ccfd69904934279c7a87a0f468b3f81 349 Gene3D G3DSA:3.40.50.720 139 322 4.4E-33 T 29-03-2018 A616_RS25005 0ccfd69904934279c7a87a0f468b3f81 349 SUPERFAMILY SSF51735 3 349 2.42E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS25005 0ccfd69904934279c7a87a0f468b3f81 349 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 190 336 4.9E-41 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS25005 0ccfd69904934279c7a87a0f468b3f81 349 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 179 1.3E-31 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS25005 0ccfd69904934279c7a87a0f468b3f81 349 Gene3D G3DSA:3.30.1780.10 3 138 1.0E-33 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 96 112 4.7E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 81 96 4.7E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 SUPERFAMILY SSF53807 117 370 1.13E-37 T 29-03-2018 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 SMART SM00342 29 112 1.8E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 Pfam PF01497 Periplasmic binding protein 119 354 4.6E-15 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 Gene3D G3DSA:1.10.10.60 7 63 4.7E-12 T 29-03-2018 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 Gene3D G3DSA:1.10.10.60 64 107 6.6E-16 T 29-03-2018 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 SUPERFAMILY SSF46689 15 63 2.55E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 Gene3D G3DSA:3.40.50.1980 222 380 8.9E-27 T 29-03-2018 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 Gene3D G3DSA:3.40.50.1980 108 221 3.3E-11 T 29-03-2018 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 Pfam PF12833 Helix-turn-helix domain 35 112 1.2E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS12520 52143d2e23bd65e0430f66077f49f033 396 SUPERFAMILY SSF46689 65 113 2.96E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24515 2d3918d2e1ad28e1abf3b85d755740f4 183 Pfam PF08887 GAD-like domain 18 90 1.5E-14 T 29-03-2018 IPR014983 GAD-related A616_RS24515 2d3918d2e1ad28e1abf3b85d755740f4 183 Pfam PF08906 Domain of unknown function (DUF1851) 105 179 2.2E-26 T 29-03-2018 IPR015002 Domain of unknown function DUF1851 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 Pfam PF13411 MerR HTH family regulatory protein 2 71 5.7E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 SUPERFAMILY SSF55136 119 265 1.1E-8 T 29-03-2018 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 SMART SM00422 2 72 8.2E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 Gene3D G3DSA:1.10.1660.10 1 58 2.6E-19 T 29-03-2018 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 Gene3D G3DSA:1.10.1660.10 59 125 9.0E-7 T 29-03-2018 A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 Gene3D G3DSA:3.20.80.10 126 266 2.5E-12 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 SMART SM00871 118 265 1.9E-10 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 SUPERFAMILY SSF46955 2 105 4.4E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS01870 24c9edc8c068388e4d1ebc474fdc4aec 267 Pfam PF06445 GyrI-like small molecule binding domain 119 264 5.1E-8 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain A616_RS28430 c8c7d7ae2ad3986ac7ff87087456d64e 100 Pfam PF09862 Protein of unknown function (DUF2089) 10 83 3.3E-15 T 29-03-2018 IPR018658 Protein of unknown function DUF2089 A616_RS28430 c8c7d7ae2ad3986ac7ff87087456d64e 100 Gene3D G3DSA:1.10.10.10 12 75 1.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06470 037c113e4d185cf2d6e4c46acc9e5bab 152 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 25 147 5.2E-15 T 29-03-2018 IPR006480 Bacteriophage holin family A616_RS06470 037c113e4d185cf2d6e4c46acc9e5bab 152 Pfam PF05105 Bacteriophage holin family 40 135 6.9E-14 T 29-03-2018 IPR006480 Bacteriophage holin family A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 294 317 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 Pfam PF00375 Sodium:dicarboxylate symporter family 8 399 1.1E-111 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 Gene3D G3DSA:1.10.3860.10 2 407 2.6E-119 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 SUPERFAMILY SSF118215 8 400 4.32E-119 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 144 166 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 217 236 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS07420 b095b48059662b66edb4b31711ec3ad4 430 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 1.1E-33 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 216 227 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 548 1.3E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 Pfam PF00501 AMP-binding enzyme 35 463 2.9E-116 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 Gene3D G3DSA:2.30.38.10 374 457 2.9E-29 T 29-03-2018 A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 Gene3D G3DSA:3.30.300.30 459 569 1.4E-31 T 29-03-2018 A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 Gene3D G3DSA:3.40.50.980 222 373 3.1E-46 T 29-03-2018 A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 SUPERFAMILY SSF56801 18 559 3.53E-165 T 29-03-2018 A616_RS09700 c75be1b969dcb88a133d92e772be68ef 571 Gene3D G3DSA:3.40.50.980 28 221 3.4E-42 T 29-03-2018 A616_RS11905 64058d17828a9275ffec1fa8262e39e7 267 Pfam PF00072 Response regulator receiver domain 151 262 5.8E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS11905 64058d17828a9275ffec1fa8262e39e7 267 SUPERFAMILY SSF52172 148 266 2.28E-27 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS11905 64058d17828a9275ffec1fa8262e39e7 267 Gene3D G3DSA:3.40.50.2300 139 267 1.4E-28 T 29-03-2018 A616_RS11905 64058d17828a9275ffec1fa8262e39e7 267 SMART SM00448 148 262 7.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27905 86beb1089350fac926d6b21e5f4ecc9b 494 Pfam PF01425 Amidase 25 471 3.8E-100 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS27905 86beb1089350fac926d6b21e5f4ecc9b 494 Gene3D G3DSA:3.90.1300.10 1 494 5.0E-131 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS27905 86beb1089350fac926d6b21e5f4ecc9b 494 PIRSF PIRSF001221 449 481 0.22 T 29-03-2018 A616_RS27905 86beb1089350fac926d6b21e5f4ecc9b 494 PIRSF PIRSF001221 413 453 21.0 T 29-03-2018 A616_RS27905 86beb1089350fac926d6b21e5f4ecc9b 494 PIRSF PIRSF001221 2 412 3.0E-55 T 29-03-2018 A616_RS27905 86beb1089350fac926d6b21e5f4ecc9b 494 SUPERFAMILY SSF75304 2 476 1.57E-124 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 A616_RS14725 1afff94110c92cff4de69c9542b94a5d 119 Gene3D G3DSA:3.30.1330.20 2 118 2.0E-45 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A616_RS14725 1afff94110c92cff4de69c9542b94a5d 119 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 3 119 2.0E-53 T 29-03-2018 IPR011719 Conserved hypothetical protein CHP02058 A616_RS14725 1afff94110c92cff4de69c9542b94a5d 119 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 5 117 3.9E-43 T 29-03-2018 IPR011719 Conserved hypothetical protein CHP02058 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 Gene3D G3DSA:2.60.200.20 6 136 1.5E-20 T 29-03-2018 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 Pfam PF00498 FHA domain 29 96 8.7E-16 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 SUPERFAMILY SSF49879 17 106 8.42E-22 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 Gene3D G3DSA:1.10.10.10 137 230 3.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 SMART SM00862 147 228 2.8E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 SMART SM00240 28 81 1.3E-8 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 SUPERFAMILY SSF46894 125 229 7.09E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS25930 706f39ff71a6adc5b94cab125b111e30 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 227 4.1E-12 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS14320 d847a230e0fd2d946d66d29284eade02 595 SUPERFAMILY SSF55486 49 590 1.5E-86 T 29-03-2018 A616_RS14320 d847a230e0fd2d946d66d29284eade02 595 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 4 589 2.0E-183 T 29-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 A616_RS14320 d847a230e0fd2d946d66d29284eade02 595 Pfam PF08439 Oligopeptidase F 115 173 1.3E-9 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A616_RS14320 d847a230e0fd2d946d66d29284eade02 595 Pfam PF01432 Peptidase family M3 195 576 1.7E-25 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS14320 d847a230e0fd2d946d66d29284eade02 595 Gene3D G3DSA:1.10.1370.10 18 560 3.7E-19 T 29-03-2018 A616_RS30025 f7acc64853e12b41e0832f4a33fd22c0 359 SUPERFAMILY SSF55821 24 218 7.94E-69 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A616_RS30025 f7acc64853e12b41e0832f4a33fd22c0 359 PIRSF PIRSF004930 5 359 2.4E-129 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A616_RS30025 f7acc64853e12b41e0832f4a33fd22c0 359 Pfam PF01300 Telomere recombination 31 206 1.9E-61 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 A616_RS30025 f7acc64853e12b41e0832f4a33fd22c0 359 Gene3D G3DSA:3.90.870.10 8 222 1.6E-82 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A616_RS30025 f7acc64853e12b41e0832f4a33fd22c0 359 Pfam PF03481 Putative GTP-binding controlling metal-binding 208 353 4.2E-26 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A616_RS30025 f7acc64853e12b41e0832f4a33fd22c0 359 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 217 1.5E-68 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 Gene3D G3DSA:3.90.870.10 1 210 1.8E-94 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A616_RS26535 6157043f87b255513225da9d054c5ff6 399 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 206 395 5.2E-79 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 1.7E-80 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 SUPERFAMILY SSF55821 2 204 5.49E-85 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A616_RS26535 6157043f87b255513225da9d054c5ff6 399 Pfam PF00925 GTP cyclohydrolase II 206 371 2.5E-77 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 55.565 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 2.8E-84 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 PIRSF PIRSF001259 1 399 1.3E-189 T 29-03-2018 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 38.324 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 SUPERFAMILY SSF142695 203 374 2.09E-75 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A616_RS26535 6157043f87b255513225da9d054c5ff6 399 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.427 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A616_RS11990 82876ce8e196aab23c6bc554894ba554 134 Gene3D G3DSA:2.170.270.10 1 119 6.3E-20 T 29-03-2018 A616_RS11990 82876ce8e196aab23c6bc554894ba554 134 SUPERFAMILY SSF82199 12 115 2.62E-22 T 29-03-2018 A616_RS11990 82876ce8e196aab23c6bc554894ba554 134 SMART SM00317 2 117 7.1E-4 T 29-03-2018 IPR001214 SET domain GO:0005515 A616_RS11990 82876ce8e196aab23c6bc554894ba554 134 PIRSF PIRSF022536 1 131 4.7E-32 T 29-03-2018 IPR009207 Histone methyltransferase, PBCV type putative KEGG: 00310+2.1.1.43 A616_RS11990 82876ce8e196aab23c6bc554894ba554 134 Pfam PF00856 SET domain 16 111 4.3E-14 T 29-03-2018 IPR001214 SET domain GO:0005515 A616_RS10855 8ab144f1d3968696224b25316d02d4ef 366 Gene3D G3DSA:3.30.160.60 96 130 2.3E-7 T 29-03-2018 A616_RS10855 8ab144f1d3968696224b25316d02d4ef 366 Gene3D G3DSA:3.30.160.60 334 366 5.4E-9 T 29-03-2018 A616_RS10855 8ab144f1d3968696224b25316d02d4ef 366 Pfam PF02618 YceG-like family 64 361 2.5E-85 T 29-03-2018 IPR003770 Endolytic murein transglycosylase A616_RS10855 8ab144f1d3968696224b25316d02d4ef 366 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 30 365 34.008 T 29-03-2018 IPR003770 Endolytic murein transglycosylase A616_RS10855 8ab144f1d3968696224b25316d02d4ef 366 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 30 360 2.1E-81 T 29-03-2018 IPR003770 Endolytic murein transglycosylase A616_RS04955 665da1e10945c7acb9cb1c2227b3483a 377 SUPERFAMILY SSF51905 3 217 6.15E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS04955 665da1e10945c7acb9cb1c2227b3483a 377 SUPERFAMILY SSF51905 319 376 6.15E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS04955 665da1e10945c7acb9cb1c2227b3483a 377 SUPERFAMILY SSF54373 217 319 7.06E-26 T 29-03-2018 A616_RS04955 665da1e10945c7acb9cb1c2227b3483a 377 Pfam PF01266 FAD dependent oxidoreductase 5 358 2.6E-50 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS04955 665da1e10945c7acb9cb1c2227b3483a 377 Gene3D G3DSA:3.40.50.720 2 68 1.7E-4 T 29-03-2018 A616_RS04955 665da1e10945c7acb9cb1c2227b3483a 377 Gene3D G3DSA:3.30.9.10 69 319 1.7E-42 T 29-03-2018 A616_RS10165 0233f4f3340e75fcd142cdbada253b53 554 Gene3D G3DSA:3.10.105.10 314 524 1.2E-51 T 29-03-2018 A616_RS10165 0233f4f3340e75fcd142cdbada253b53 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 471 2.9E-85 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS10165 0233f4f3340e75fcd142cdbada253b53 554 Gene3D G3DSA:3.40.190.10 219 313 1.7E-22 T 29-03-2018 A616_RS10165 0233f4f3340e75fcd142cdbada253b53 554 SUPERFAMILY SSF53850 51 548 9.23E-132 T 29-03-2018 A616_RS10165 0233f4f3340e75fcd142cdbada253b53 554 Gene3D G3DSA:3.90.76.10 61 218 2.8E-41 T 29-03-2018 A616_RS10165 0233f4f3340e75fcd142cdbada253b53 554 PIRSF PIRSF002741 1 551 3.8E-120 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 Gene3D G3DSA:1.25.40.20 2 93 4.1E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 Gene3D G3DSA:1.25.40.20 94 156 1.4E-19 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 SUPERFAMILY SSF48403 8 155 3.01E-33 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 PRINTS PR01415 Ankyrin repeat signature 118 132 2.5E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 PRINTS PR01415 Ankyrin repeat signature 101 116 2.5E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 SMART SM00248 37 66 0.06 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 SMART SM00248 3 32 740.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 SMART SM00248 70 96 0.079 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 SMART SM00248 100 131 0.19 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS10920 3a5f83e98b1b95909b19df8ec100c0d7 156 Pfam PF12796 Ankyrin repeats (3 copies) 42 133 1.2E-12 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS17105 befe7e7d343ee5fa61cb2e0b1ab974b0 209 Pfam PF01381 Helix-turn-helix 17 69 4.7E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS17105 befe7e7d343ee5fa61cb2e0b1ab974b0 209 Gene3D G3DSA:1.10.260.40 3 184 5.7E-17 T 29-03-2018 A616_RS17105 befe7e7d343ee5fa61cb2e0b1ab974b0 209 SMART SM00530 16 71 3.8E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS17105 befe7e7d343ee5fa61cb2e0b1ab974b0 209 SUPERFAMILY SSF47413 9 73 3.94E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS03390 22c608a144483046533552a15d0196d4 464 Gene3D G3DSA:3.20.20.80 62 329 1.1E-7 T 29-03-2018 A616_RS03390 22c608a144483046533552a15d0196d4 464 Gene3D G3DSA:2.70.50.60 330 445 4.6E-6 T 29-03-2018 A616_RS03390 22c608a144483046533552a15d0196d4 464 Pfam PF16116 Domain of unknown function (DUF4832) 234 445 7.4E-44 T 29-03-2018 IPR032267 Domain of unknown function DUF4832 A616_RS03390 22c608a144483046533552a15d0196d4 464 Pfam PF02449 Beta-galactosidase 66 182 2.7E-5 T 29-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A616_RS03390 22c608a144483046533552a15d0196d4 464 SUPERFAMILY SSF51445 66 200 5.86E-10 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS09315 73c91adc19bc32663f0880675510aa9d 528 Gene3D G3DSA:3.10.105.10 305 496 1.2E-57 T 29-03-2018 A616_RS09315 73c91adc19bc32663f0880675510aa9d 528 Gene3D G3DSA:3.40.190.10 170 304 2.5E-49 T 29-03-2018 A616_RS09315 73c91adc19bc32663f0880675510aa9d 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 446 9.7E-100 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS09315 73c91adc19bc32663f0880675510aa9d 528 Gene3D G3DSA:3.90.76.10 67 169 3.1E-31 T 29-03-2018 A616_RS09315 73c91adc19bc32663f0880675510aa9d 528 SUPERFAMILY SSF53850 48 527 3.26E-150 T 29-03-2018 A616_RS09315 73c91adc19bc32663f0880675510aa9d 528 PIRSF PIRSF002741 1 527 1.8E-132 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 Pfam PF00271 Helicase conserved C-terminal domain 230 327 1.5E-18 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 Gene3D G3DSA:3.40.50.300 204 471 3.2E-45 T 29-03-2018 A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 Gene3D G3DSA:3.40.50.300 2 202 8.9E-34 T 29-03-2018 A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 Pfam PF16124 RecQ zinc-binding 418 467 2.0E-5 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 SMART SM00490 246 328 1.6E-23 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 SMART SM00487 15 212 3.1E-26 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 Pfam PF00270 DEAD/DEAH box helicase 21 182 8.5E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 SUPERFAMILY SSF52540 59 349 7.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13565 d7e9b42175231da3b55d7e9b060b346b 503 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 10 361 2.6E-112 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 199 36.914 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 SMART SM01390 3 90 3.6E-43 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 Gene3D G3DSA:1.10.1050.10 139 199 3.2E-15 T 29-03-2018 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 Pfam PF01479 S4 domain 92 138 1.0E-22 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 199 2.2E-82 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 SMART SM00363 91 151 1.2E-23 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 Gene3D G3DSA:3.10.290.10 97 138 5.1E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 Gene3D G3DSA:1.10.1050.10 1 96 1.3E-39 T 29-03-2018 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 1.4E-29 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 SUPERFAMILY SSF55174 3 199 8.24E-70 T 29-03-2018 A616_RS22950 5899da0d91b3544a54958da2348ce5e4 199 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 Pfam PF03466 LysR substrate binding domain 86 286 8.3E-43 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.8E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 SUPERFAMILY SSF53850 87 286 8.36E-38 T 29-03-2018 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 Gene3D G3DSA:3.40.190.10 81 173 2.8E-16 T 29-03-2018 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 Gene3D G3DSA:1.10.10.10 1 80 9.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 Gene3D G3DSA:3.40.190.10 174 259 1.4E-12 T 29-03-2018 A616_RS31825 ef04418618491cb28f2b4470981de0c8 290 SUPERFAMILY SSF46785 1 109 1.51E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 SUPERFAMILY SSF100950 3 223 1.49E-64 T 29-03-2018 A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 11 495 3.6E-229 T 29-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 Gene3D G3DSA:3.40.1080.10 12 237 4.0E-33 T 29-03-2018 A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 Gene3D G3DSA:3.40.1080.10 238 500 2.3E-59 T 29-03-2018 A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 326 464 2.2E-43 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 8 216 1.3E-24 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 A616_RS02150 d80ccd0a6ad1b6dc378f679c724e078d 503 SUPERFAMILY SSF100950 226 495 6.61E-86 T 29-03-2018 A616_RS12220 0f4622d249434bc43e7e90cf2e99d6c6 102 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 95 8.4E-9 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS12220 0f4622d249434bc43e7e90cf2e99d6c6 102 Gene3D G3DSA:2.60.300.12 1 99 1.2E-12 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS12220 0f4622d249434bc43e7e90cf2e99d6c6 102 SUPERFAMILY SSF89360 1 91 9.02E-12 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 Pfam PF01546 Peptidase family M20/M25/M40 141 403 1.1E-12 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 SUPERFAMILY SSF55031 211 321 3.35E-38 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 58.351 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 Pfam PF07687 Peptidase dimerisation domain 209 310 2.5E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 SUPERFAMILY SSF53187 4 212 1.31E-80 T 29-03-2018 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 SUPERFAMILY SSF53187 324 406 1.31E-80 T 29-03-2018 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 PIRSF PIRSF037215 1 410 4.1E-191 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 4 409 2.2E-200 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 A616_RS16055 20f84542b8cd7db7aa62b8833f6d1065 410 Gene3D G3DSA:3.40.630.10 1 410 1.2E-49 T 29-03-2018 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 SUPERFAMILY SSF53067 6 170 7.77E-62 T 29-03-2018 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PIRSF PIRSF000722 44 372 2.9E-127 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PIRSF PIRSF000722 3 50 4.1E-6 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 Pfam PF00871 Acetokinase family 7 363 2.5E-133 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 Hamap MF_00020 Acetate kinase [ackA]. 1 372 153.059 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 SUPERFAMILY SSF53067 133 369 2.72E-85 T 29-03-2018 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 Gene3D G3DSA:3.30.420.40 171 372 5.6E-69 T 29-03-2018 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 Gene3D G3DSA:3.30.420.40 6 170 1.4E-62 T 29-03-2018 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PRINTS PR00471 Acetate kinase family signature 275 288 5.9E-43 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PRINTS PR00471 Acetate kinase family signature 7 18 5.9E-43 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PRINTS PR00471 Acetate kinase family signature 178 199 5.9E-43 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PRINTS PR00471 Acetate kinase family signature 351 363 5.9E-43 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PRINTS PR00471 Acetate kinase family signature 297 313 5.9E-43 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 PRINTS PR00471 Acetate kinase family signature 148 161 5.9E-43 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 178 195 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS27250 b3607985f519c1b5a56e924acf98d957 372 TIGRFAM TIGR00016 ackA: acetate kinase 54 369 4.1E-132 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A616_RS25585 c114e05dbc99fbcc5bb359f2f9f49b4e 471 Pfam PF00144 Beta-lactamase 11 355 1.7E-68 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS25585 c114e05dbc99fbcc5bb359f2f9f49b4e 471 SUPERFAMILY SSF56601 4 357 1.61E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25585 c114e05dbc99fbcc5bb359f2f9f49b4e 471 Gene3D G3DSA:3.40.710.10 2 369 2.1E-82 T 29-03-2018 A616_RS04665 18de0656fead47635be6c67c01f4f102 117 Pfam PF05656 Protein of unknown function (DUF805) 11 111 1.6E-33 T 29-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 A616_RS03495 d191276f5cc383ea88723166a3aa0a37 173 SUPERFAMILY SSF109854 2 65 5.34E-21 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS03495 d191276f5cc383ea88723166a3aa0a37 173 SUPERFAMILY SSF109854 97 169 5.34E-21 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS03495 d191276f5cc383ea88723166a3aa0a37 173 Gene3D G3DSA:1.20.120.450 1 173 1.7E-30 T 29-03-2018 A616_RS03495 d191276f5cc383ea88723166a3aa0a37 173 Pfam PF12867 DinB superfamily 10 168 9.9E-15 T 29-03-2018 IPR024775 DinB-like domain A616_RS02185 7facc2e7dd1d55ebd0491af78b57a17c 257 Pfam PF05726 Pirin C-terminal cupin domain 169 224 6.4E-5 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 A616_RS02185 7facc2e7dd1d55ebd0491af78b57a17c 257 SUPERFAMILY SSF51182 34 247 4.68E-38 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS02185 7facc2e7dd1d55ebd0491af78b57a17c 257 Gene3D G3DSA:2.60.120.10 28 248 6.7E-40 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS02185 7facc2e7dd1d55ebd0491af78b57a17c 257 Pfam PF02678 Pirin 54 117 1.3E-17 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 SUPERFAMILY SSF89260 876 977 1.12E-22 T 29-03-2018 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 Pfam PF01752 Collagenase 314 639 4.7E-75 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 SMART SM00089 787 869 1.2E-21 T 29-03-2018 IPR022409 PKD/Chitinase domain A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 Pfam PF08453 Peptidase family M9 N-terminal 110 286 1.2E-44 T 29-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 Gene3D G3DSA:2.60.120.380 989 1104 1.0E-19 T 29-03-2018 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 Gene3D G3DSA:2.60.120.380 874 988 2.7E-18 T 29-03-2018 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 176 194 5.4E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 476 492 5.4E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 459 473 5.4E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 513 531 5.4E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 539 554 5.4E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 SUPERFAMILY SSF89260 993 1103 1.01E-22 T 29-03-2018 A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 SUPERFAMILY SSF49299 783 867 1.01E-20 T 29-03-2018 IPR000601 PKD domain A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 Gene3D G3DSA:2.60.40.10 777 868 7.4E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS23685 978cdac20b794fdeacf8229dbcf03a04 1105 Pfam PF00801 PKD domain 792 859 1.2E-17 T 29-03-2018 IPR000601 PKD domain A616_RS29650 23f884869f944e41217f5d75ebc920ff 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 232 2.1E-61 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS29650 23f884869f944e41217f5d75ebc920ff 306 Gene3D G3DSA:3.40.50.720 1 162 2.2E-36 T 29-03-2018 A616_RS29650 23f884869f944e41217f5d75ebc920ff 306 Gene3D G3DSA:3.90.25.10 163 304 1.2E-39 T 29-03-2018 A616_RS29650 23f884869f944e41217f5d75ebc920ff 306 SUPERFAMILY SSF51735 1 302 4.23E-97 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20320 cfa1164ed032ef253f25177818d79225 259 Pfam PF06182 ABC-2 family transporter protein 48 258 1.1E-13 T 29-03-2018 IPR010390 Protein of unknown function DUF990 A616_RS21680 673b8514da198b051fbeab04ac255fb7 224 SUPERFAMILY SSF53822 25 135 2.07E-5 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS21680 673b8514da198b051fbeab04ac255fb7 224 Gene3D G3DSA:3.40.50.1860 7 194 1.1E-9 T 29-03-2018 A616_RS23015 6b7a94ab7fe423a9a8a2bf4c60f17c4c 30 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 10 29 1.4E-8 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS23015 6b7a94ab7fe423a9a8a2bf4c60f17c4c 30 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 10 27 4.4E-7 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS01555 4395244354b8acb1be28594872424b73 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 36.557 T 29-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 A616_RS01555 4395244354b8acb1be28594872424b73 265 Pfam PF02361 Cobalt transport protein 14 231 4.4E-52 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 SMART SM00862 162 234 2.1E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 Gene3D G3DSA:1.10.10.10 134 239 1.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 234 3.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 Pfam PF00072 Response regulator receiver domain 5 115 1.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 SUPERFAMILY SSF46894 142 235 4.25E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 Gene3D G3DSA:3.40.50.2300 2 133 5.6E-41 T 29-03-2018 A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 SUPERFAMILY SSF52172 4 129 7.26E-44 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS05680 ad58f3a99c75b2dbd06a00aaaa3c83a6 239 SMART SM00448 3 114 5.7E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS21475 82ade14efc411e34bd30436a060c35dc 158 SUPERFAMILY SSF109854 6 154 1.78E-24 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS21475 82ade14efc411e34bd30436a060c35dc 158 Gene3D G3DSA:1.20.120.450 5 152 4.5E-20 T 29-03-2018 A616_RS21475 82ade14efc411e34bd30436a060c35dc 158 Pfam PF12867 DinB superfamily 10 146 9.3E-20 T 29-03-2018 IPR024775 DinB-like domain A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 PIRSF PIRSF002937 1 262 5.8E-131 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 SUPERFAMILY SSF46894 146 259 9.35E-48 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 SMART SM00448 4 119 1.3E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 151 260 7.0E-56 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 Gene3D G3DSA:3.40.50.2300 3 145 3.0E-34 T 29-03-2018 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 Gene3D G3DSA:1.10.10.10 148 258 1.1E-53 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 SUPERFAMILY SSF52172 2 126 6.97E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 152 255 2.8E-45 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 Pfam PF00072 Response regulator receiver domain 6 120 3.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS13180 f20b538d3ac976bbc8440d15c62ffde3 262 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 262 1.7E-127 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 Pfam PF08360 QacR-like protein, C-terminal region 67 196 4.9E-28 T 29-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 Gene3D G3DSA:1.10.10.60 1 46 1.6E-19 T 29-03-2018 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 SUPERFAMILY SSF46689 2 73 2.41E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 SUPERFAMILY SSF48498 82 195 4.75E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 Gene3D G3DSA:1.10.10.60 47 71 4.4E-13 T 29-03-2018 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 7.3E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS12335 e21c9ce9bc2215f4f4dbc826f4680e14 197 Gene3D G3DSA:1.10.357.10 72 197 1.8E-19 T 29-03-2018 A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 SUPERFAMILY SSF158472 339 390 1.7E-6 T 29-03-2018 A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 Pfam PF06580 Histidine kinase 403 481 5.1E-20 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 498 622 4.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 SUPERFAMILY SSF55874 460 621 1.83E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 SMART SM00387 497 624 9.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 Gene3D G3DSA:3.30.450.20 186 316 8.1E-4 T 29-03-2018 A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 Gene3D G3DSA:3.30.565.10 385 623 2.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS24830 571aaf98718eea29c4ea75768d2eb927 633 SMART SM00304 338 391 6.7E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 SUPERFAMILY SSF49503 579 704 1.68E-19 T 29-03-2018 IPR008972 Cupredoxin A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 SUPERFAMILY SSF49503 302 425 3.97E-30 T 29-03-2018 IPR008972 Cupredoxin A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 Pfam PF07732 Multicopper oxidase 318 425 2.7E-25 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 Gene3D G3DSA:2.60.40.420 571 707 1.7E-17 T 29-03-2018 IPR008972 Cupredoxin A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 SUPERFAMILY SSF49503 455 527 1.28E-10 T 29-03-2018 IPR008972 Cupredoxin A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 Pfam PF07731 Multicopper oxidase 613 684 3.4E-8 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 Gene3D G3DSA:2.60.40.420 282 426 3.4E-28 T 29-03-2018 IPR008972 Cupredoxin A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 Gene3D G3DSA:2.60.40.420 439 540 1.5E-12 T 29-03-2018 IPR008972 Cupredoxin A616_RS27625 0988f2840199ee468d4c32052b0f40d6 709 Pfam PF00394 Multicopper oxidase 427 525 1.3E-6 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 A616_RS17785 565f9e43400a5c20a2682216ca176f32 435 Gene3D G3DSA:3.40.640.10 63 264 7.7E-18 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS17785 565f9e43400a5c20a2682216ca176f32 435 Pfam PF00155 Aminotransferase class I and II 62 418 1.3E-31 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS17785 565f9e43400a5c20a2682216ca176f32 435 SUPERFAMILY SSF53383 24 417 3.14E-61 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS17785 565f9e43400a5c20a2682216ca176f32 435 Gene3D G3DSA:3.90.1150.10 265 432 1.1E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS08525 62e4ea355ada5217e863b1567018341c 200 SUPERFAMILY SSF50475 32 178 1.23E-16 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS08525 62e4ea355ada5217e863b1567018341c 200 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 44 130 1.9E-12 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A616_RS08525 62e4ea355ada5217e863b1567018341c 200 Gene3D G3DSA:2.30.110.10 27 187 7.9E-24 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS08525 62e4ea355ada5217e863b1567018341c 200 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 15 190 1.4E-67 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent A616_RS16660 17b078022d3ee86056ff127f051935bc 192 Gene3D G3DSA:1.10.530.10 52 191 4.0E-15 T 29-03-2018 A616_RS16660 17b078022d3ee86056ff127f051935bc 192 SUPERFAMILY SSF53955 55 185 4.93E-16 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS16660 17b078022d3ee86056ff127f051935bc 192 Pfam PF01464 Transglycosylase SLT domain 58 174 2.2E-14 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 SUPERFAMILY SSF88946 16 105 6.28E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 1.4E-111 T 29-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 SUPERFAMILY SSF88659 123 211 1.16E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 Gene3D G3DSA:1.10.10.10 137 216 1.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 PIRSF PIRSF002939 2 216 7.7E-109 T 29-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 2.4E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 Gene3D G3DSA:1.10.1740.10 12 116 7.8E-21 T 29-03-2018 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 Pfam PF04542 Sigma-70 region 2 36 105 1.1E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS01300 622af3ec7541b08f03647c2695ae5b67 216 Pfam PF08281 Sigma-70, region 4 163 205 3.9E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18425 403640b11ebb0f32384918dd8eab5b7c 56 Pfam PF15777 Tryptophan RNA-binding attenuator protein inhibitory protein 1 56 9.4E-22 T 29-03-2018 IPR031538 Tryptophan RNA-binding attenuator protein inhibitory protein A616_RS18425 403640b11ebb0f32384918dd8eab5b7c 56 Gene3D G3DSA:2.10.230.10 7 54 4.4E-6 T 29-03-2018 A616_RS18425 403640b11ebb0f32384918dd8eab5b7c 56 SUPERFAMILY SSF57938 10 47 3.66E-6 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A616_RS02950 a2c2a64a915d696af0c7b3016db6df21 240 SUPERFAMILY SSF53067 1 102 2.07E-25 T 29-03-2018 A616_RS02950 a2c2a64a915d696af0c7b3016db6df21 240 Gene3D G3DSA:3.30.420.40 1 138 2.0E-34 T 29-03-2018 A616_RS02950 a2c2a64a915d696af0c7b3016db6df21 240 Pfam PF00814 Glycoprotease family 23 229 4.5E-29 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS02950 a2c2a64a915d696af0c7b3016db6df21 240 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 221 1.6E-52 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 A616_RS02950 a2c2a64a915d696af0c7b3016db6df21 240 SUPERFAMILY SSF53067 108 219 3.88E-15 T 29-03-2018 A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 SUPERFAMILY SSF46548 257 311 1.22E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 SUPERFAMILY SSF46548 344 390 1.22E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 Pfam PF02754 Cysteine-rich domain 568 655 3.8E-16 T 29-03-2018 IPR004017 Cysteine-rich domain A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 Pfam PF02754 Cysteine-rich domain 446 529 9.7E-8 T 29-03-2018 IPR004017 Cysteine-rich domain A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 Gene3D G3DSA:1.20.950.20 2 235 6.6E-44 T 29-03-2018 A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 Pfam PF13183 4Fe-4S dicluster domain 272 375 2.6E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 362 373 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 SUPERFAMILY SSF103501 6 241 3.01E-18 T 29-03-2018 IPR023234 NarG-like domain A616_RS15430 6ca6dd91849b2fe1a9911adbedb9353f 681 Gene3D G3DSA:1.10.1060.10 242 395 3.7E-33 T 29-03-2018 A616_RS02740 aaf1f3101f445d547bd4b45ecc5e554a 158 Gene3D G3DSA:1.20.58.130 12 67 7.8E-4 T 29-03-2018 A616_RS12565 9987f8f44d384694234d44979378091b 267 Gene3D G3DSA:3.40.50.300 8 227 1.5E-57 T 29-03-2018 A616_RS12565 9987f8f44d384694234d44979378091b 267 Pfam PF00005 ABC transporter 31 169 7.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12565 9987f8f44d384694234d44979378091b 267 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS12565 9987f8f44d384694234d44979378091b 267 SUPERFAMILY SSF52540 12 222 9.78E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12565 9987f8f44d384694234d44979378091b 267 SMART SM00382 39 220 1.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25065 d4dc11d82d7c15eade1a1e00fc14aaba 62 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 4.1E-27 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS25065 d4dc11d82d7c15eade1a1e00fc14aaba 62 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 7.0E-16 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS25065 d4dc11d82d7c15eade1a1e00fc14aaba 62 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 20.232 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS25065 d4dc11d82d7c15eade1a1e00fc14aaba 62 Pfam PF08141 Small acid-soluble spore protein H family 1 58 1.3E-25 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS28615 a174af1fe5e8a5a28fc31abddbedd07c 326 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 35 84 6.0E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS28615 a174af1fe5e8a5a28fc31abddbedd07c 326 Gene3D G3DSA:1.10.3720.10 44 310 1.7E-43 T 29-03-2018 A616_RS28615 a174af1fe5e8a5a28fc31abddbedd07c 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 309 4.8E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28615 a174af1fe5e8a5a28fc31abddbedd07c 326 SUPERFAMILY SSF161098 103 293 1.7E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31365 ff3214b477178978a75c4d40ca510da1 438 Pfam PF13416 Bacterial extracellular solute-binding protein 63 371 1.9E-59 T 29-03-2018 A616_RS31365 ff3214b477178978a75c4d40ca510da1 438 SUPERFAMILY SSF53850 43 430 1.63E-93 T 29-03-2018 A616_RS31365 ff3214b477178978a75c4d40ca510da1 438 Gene3D G3DSA:3.40.190.10 225 391 2.0E-14 T 29-03-2018 A616_RS31365 ff3214b477178978a75c4d40ca510da1 438 Gene3D G3DSA:3.40.190.10 42 224 6.5E-45 T 29-03-2018 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 SUPERFAMILY SSF51735 12 169 8.25E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 11 275 26.954 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 Gene3D G3DSA:3.40.50.720 9 173 1.3E-26 T 29-03-2018 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 231 253 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 PIRSF PIRSF000193 10 278 5.1E-80 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 171 275 4.8E-36 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 SUPERFAMILY SSF48179 171 278 1.6E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 13 275 2.2E-87 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 Gene3D G3DSA:1.10.3730.10 174 280 1.4E-39 T 29-03-2018 A616_RS27010 a0fde3a36784c307f44398fca6fdbec2 280 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 12 108 5.3E-20 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A616_RS21365 dc6ce7bfaa9bfd6bedcbc5ea7421931c 540 PIRSF PIRSF012535 1 540 4.5E-144 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC A616_RS21365 dc6ce7bfaa9bfd6bedcbc5ea7421931c 540 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 540 29.286 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC A616_RS21365 dc6ce7bfaa9bfd6bedcbc5ea7421931c 540 Pfam PF10079 Bacillithiol biosynthesis BshC 1 536 3.3E-167 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC A616_RS21365 dc6ce7bfaa9bfd6bedcbc5ea7421931c 540 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 12 537 5.4E-165 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 8.5E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 8.5E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 8.5E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 8.5E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 5.0E-5 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.054 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 6.8E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 Pfam PF01165 Ribosomal protein S21 4 57 2.8E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11590 cc0fcd4d3efd1c639688a948588532b6 57 Gene3D G3DSA:1.20.5.1150 16 52 3.2E-16 T 29-03-2018 A616_RS05860 2c26b6067bc5948d9bb64271bca1f9be 490 SUPERFAMILY SSF69279 11 168 1.87E-24 T 29-03-2018 A616_RS05860 2c26b6067bc5948d9bb64271bca1f9be 490 Gene3D G3DSA:3.55.50.10 100 177 3.1E-11 T 29-03-2018 A616_RS05860 2c26b6067bc5948d9bb64271bca1f9be 490 Pfam PF05954 Phage late control gene D protein (GPD) 61 166 1.4E-9 T 29-03-2018 A616_RS05860 2c26b6067bc5948d9bb64271bca1f9be 490 Gene3D G3DSA:2.40.50.260 290 391 2.4E-4 T 29-03-2018 A616_RS06735 a32ee2bbb4de77c990a1809d7ebc60d4 250 Pfam PF12695 Alpha/beta hydrolase family 66 229 1.2E-57 T 29-03-2018 IPR029059 Alpha/beta hydrolase fold-5 A616_RS06735 a32ee2bbb4de77c990a1809d7ebc60d4 250 SUPERFAMILY SSF53474 58 240 7.71E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS06735 a32ee2bbb4de77c990a1809d7ebc60d4 250 Gene3D G3DSA:3.40.50.1820 12 245 1.2E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS06735 a32ee2bbb4de77c990a1809d7ebc60d4 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 139 152 6.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS06735 a32ee2bbb4de77c990a1809d7ebc60d4 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 94 6.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS06735 a32ee2bbb4de77c990a1809d7ebc60d4 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 6.1E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS00580 4c9c853d2147ca6fcc77e4476cccc7b0 326 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 16 195 9.7E-66 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00580 4c9c853d2147ca6fcc77e4476cccc7b0 326 Pfam PF13177 DNA polymerase III, delta subunit 9 167 1.7E-58 T 29-03-2018 A616_RS00580 4c9c853d2147ca6fcc77e4476cccc7b0 326 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 231 324 4.0E-6 T 29-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS00580 4c9c853d2147ca6fcc77e4476cccc7b0 326 SUPERFAMILY SSF52540 5 179 1.53E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00580 4c9c853d2147ca6fcc77e4476cccc7b0 326 Gene3D G3DSA:1.20.272.10 205 326 4.9E-26 T 29-03-2018 A616_RS00580 4c9c853d2147ca6fcc77e4476cccc7b0 326 Gene3D G3DSA:3.40.50.300 10 164 2.2E-31 T 29-03-2018 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 Gene3D G3DSA:1.10.45.10 418 457 6.4E-16 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 Gene3D G3DSA:3.30.43.10 2 93 1.0E-25 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 Gene3D G3DSA:3.30.465.10 94 239 9.0E-43 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 1.3E-67 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 SUPERFAMILY SSF56176 4 217 1.54E-76 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 Pfam PF01565 FAD binding domain 41 180 2.2E-43 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A616_RS08835 44a00b2b18714cc7002da9be672e30e6 471 SUPERFAMILY SSF55103 220 459 1.64E-64 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A616_RS05160 ebbb50f0050c950a611d427af752149b 444 SUPERFAMILY SSF111352 11 401 4.58E-112 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A616_RS05160 ebbb50f0050c950a611d427af752149b 444 ProSitePatterns PS01219 Ammonium transporters signature. 166 191 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A616_RS05160 ebbb50f0050c950a611d427af752149b 444 TIGRFAM TIGR00836 amt: ammonium transporter 13 420 2.7E-127 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 A616_RS05160 ebbb50f0050c950a611d427af752149b 444 Pfam PF00909 Ammonium Transporter Family 16 420 1.7E-118 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A616_RS05160 ebbb50f0050c950a611d427af752149b 444 Gene3D G3DSA:1.10.3430.10 5 401 1.1E-125 T 29-03-2018 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 SUPERFAMILY SSF51726 4 343 4.58E-108 T 29-03-2018 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 1.0E-127 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 23 32 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 7 342 48.095 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 Gene3D G3DSA:3.20.20.210 5 344 4.3E-98 T 29-03-2018 A616_RS10395 d9c6f17fde778a4ec72f83f8dc243538 345 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 340 2.6E-130 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A616_RS16295 05535808baa2b6aeaf5d7969b6d4f930 330 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 327 7.6E-107 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 A616_RS16295 05535808baa2b6aeaf5d7969b6d4f930 330 Gene3D G3DSA:3.20.20.30 1 330 1.4E-59 T 29-03-2018 A616_RS16295 05535808baa2b6aeaf5d7969b6d4f930 330 Pfam PF00296 Luciferase-like monooxygenase 1 304 6.2E-30 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS16295 05535808baa2b6aeaf5d7969b6d4f930 330 SUPERFAMILY SSF51679 1 329 3.06E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS25840 220cea2c95be57734c6d672ca3551359 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 2.0E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS25840 220cea2c95be57734c6d672ca3551359 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 2.0E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS25840 220cea2c95be57734c6d672ca3551359 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.0E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS25840 220cea2c95be57734c6d672ca3551359 235 Pfam PF12840 Helix-turn-helix domain 9 68 8.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25840 220cea2c95be57734c6d672ca3551359 235 SMART SM00418 9 88 1.3E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS25840 220cea2c95be57734c6d672ca3551359 235 Gene3D G3DSA:1.10.10.10 190 215 0.14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25840 220cea2c95be57734c6d672ca3551359 235 SUPERFAMILY SSF46785 6 88 2.54E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25840 220cea2c95be57734c6d672ca3551359 235 Gene3D G3DSA:1.10.10.10 2 94 9.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07350 87828695c3be2e412332d87137edc8d1 236 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 218 5.4E-50 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07350 87828695c3be2e412332d87137edc8d1 236 SUPERFAMILY SSF53790 4 235 3.4E-47 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07350 87828695c3be2e412332d87137edc8d1 236 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 5 236 7.0E-82 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 A616_RS07350 87828695c3be2e412332d87137edc8d1 236 Gene3D G3DSA:3.30.950.10 145 235 0.0011 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07350 87828695c3be2e412332d87137edc8d1 236 PIRSF PIRSF036427 3 236 5.5E-76 T 29-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 A616_RS07350 87828695c3be2e412332d87137edc8d1 236 Gene3D G3DSA:3.40.1010.10 4 144 7.0E-30 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SUPERFAMILY SSF48452 564 760 2.06E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 Pfam PF03704 Bacterial transcriptional activator domain 924 1065 1.8E-22 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SMART SM01043 924 1066 8.5E-37 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 Gene3D G3DSA:1.10.10.10 812 919 2.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 Gene3D G3DSA:1.25.40.10 546 726 2.8E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 Gene3D G3DSA:3.40.50.300 26 255 3.9E-4 T 29-03-2018 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SUPERFAMILY SSF48452 408 526 8.22E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 Gene3D G3DSA:1.25.40.10 921 1068 7.3E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SUPERFAMILY SSF48452 921 1066 6.45E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SMART SM00028 493 526 1.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SMART SM00028 412 445 300.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SMART SM00028 1016 1049 58.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 SMART SM00028 452 485 470.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS11860 fc8e1c3a8371406f4b8305f8af82be46 1068 Gene3D G3DSA:1.25.40.10 403 545 1.2E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS23215 b71ad7bfabef39372fad2eb302e8cbf0 133 Pfam PF04965 Gene 25-like lysozyme 27 117 7.4E-23 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD A616_RS23215 b71ad7bfabef39372fad2eb302e8cbf0 133 SUPERFAMILY SSF160719 24 129 2.09E-27 T 29-03-2018 A616_RS23215 b71ad7bfabef39372fad2eb302e8cbf0 133 Gene3D G3DSA:3.10.450.40 1 129 9.1E-32 T 29-03-2018 A616_RS19585 3c732cf0d06228f0dfa99df97ed5a9df 288 Gene3D G3DSA:3.40.50.970 2 72 1.5E-15 T 29-03-2018 A616_RS19585 3c732cf0d06228f0dfa99df97ed5a9df 288 Gene3D G3DSA:3.40.50.970 73 288 3.3E-47 T 29-03-2018 A616_RS19585 3c732cf0d06228f0dfa99df97ed5a9df 288 SUPERFAMILY SSF52518 11 284 1.22E-77 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold A616_RS19585 3c732cf0d06228f0dfa99df97ed5a9df 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 2.7E-32 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A616_RS19585 3c732cf0d06228f0dfa99df97ed5a9df 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 282 5.1E-96 T 29-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate A616_RS19585 3c732cf0d06228f0dfa99df97ed5a9df 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 9.4E-21 T 29-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 Gene3D G3DSA:3.10.430.100 63 146 5.0E-27 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 2.0E-25 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 SUPERFAMILY SSF55653 56 147 2.49E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 SUPERFAMILY SSF55658 1 57 5.93E-16 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 Gene3D G3DSA:3.40.5.10 1 49 1.1E-19 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.4E-39 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 6.8E-20 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32160 d3be4af2acc1c0d8f88ca42c634487a0 147 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.465 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS24085 d1bb52c9b7d22163698327c2a3ec61cb 357 Pfam PF13786 Domain of unknown function (DUF4179) 41 133 3.4E-17 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS24085 d1bb52c9b7d22163698327c2a3ec61cb 357 Gene3D G3DSA:2.60.40.1640 214 357 4.3E-21 T 29-03-2018 A616_RS24085 d1bb52c9b7d22163698327c2a3ec61cb 357 Gene3D G3DSA:2.60.40.1630 74 212 7.0E-22 T 29-03-2018 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 8.3E-109 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 469 4.9E-152 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 520 8.1E-212 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 Gene3D G3DSA:1.20.210.10 14 524 4.4E-201 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 Gene3D G3DSA:1.10.287.70 536 603 1.1E-14 T 29-03-2018 A616_RS27560 c4169d341f33e742c612ef19ee6c7d99 614 SUPERFAMILY SSF81442 13 522 5.63E-185 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 341 48.225 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 361 4.0E-140 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 SUPERFAMILY SSF51395 1 360 3.36E-107 T 29-03-2018 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 Gene3D G3DSA:3.20.20.70 1 363 3.4E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 84 103 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 297 317 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A616_RS27165 31cfca80d39b0e49e4fa30e9dc7c0972 363 Pfam PF01180 Dihydroorotate dehydrogenase 49 345 7.5E-93 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A616_RS26530 8a6f060d52cb3334046f81335e2f7b04 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 7.8E-60 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26530 8a6f060d52cb3334046f81335e2f7b04 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 1.4E-62 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26530 8a6f060d52cb3334046f81335e2f7b04 154 Gene3D G3DSA:3.40.50.960 2 68 1.8E-25 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26530 8a6f060d52cb3334046f81335e2f7b04 154 Gene3D G3DSA:3.40.50.960 69 154 3.1E-43 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26530 8a6f060d52cb3334046f81335e2f7b04 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 32.397 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26530 8a6f060d52cb3334046f81335e2f7b04 154 SUPERFAMILY SSF52121 3 153 9.68E-66 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS23865 4c125554764cc2eeb018b517bf0aa9f6 259 Pfam PF14268 YoaP-like 201 244 4.8E-20 T 29-03-2018 IPR025685 YoaP-like domain A616_RS23865 4c125554764cc2eeb018b517bf0aa9f6 259 SUPERFAMILY SSF52833 168 252 8.69E-6 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS23865 4c125554764cc2eeb018b517bf0aa9f6 259 SUPERFAMILY SSF55729 73 143 1.03E-10 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS23865 4c125554764cc2eeb018b517bf0aa9f6 259 Pfam PF00583 Acetyltransferase (GNAT) family 28 134 3.1E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS23865 4c125554764cc2eeb018b517bf0aa9f6 259 Gene3D G3DSA:3.40.630.30 17 156 6.7E-11 T 29-03-2018 A616_RS08685 b98309f767747abe7a070c5928bbce9d 236 Gene3D G3DSA:3.30.240.20 82 151 2.7E-26 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A616_RS08685 b98309f767747abe7a070c5928bbce9d 236 Gene3D G3DSA:3.30.240.20 168 227 1.9E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A616_RS08685 b98309f767747abe7a070c5928bbce9d 236 Pfam PF04239 Protein of unknown function (DUF421) 88 205 7.1E-31 T 29-03-2018 IPR007353 Protein of unknown function DUF421 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Gene3D G3DSA:3.30.413.10 141 348 1.3E-57 T 29-03-2018 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 76 138 1.2E-16 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 355 420 9.7E-14 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 SUPERFAMILY SSF56014 147 346 1.7E-61 T 29-03-2018 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 432 562 3.9E-5 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 171 332 4.1E-50 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Gene3D G3DSA:3.30.413.10 78 140 5.4E-4 T 29-03-2018 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 SUPERFAMILY SSF55124 348 424 2.78E-21 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 SUPERFAMILY SSF56014 431 563 1.44E-36 T 29-03-2018 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 PRINTS PR00397 Sirohaem Fe-binding site signature 481 499 2.2E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 PRINTS PR00397 Sirohaem Fe-binding site signature 433 451 2.2E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 SUPERFAMILY SSF55124 12 146 1.42E-33 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 9 573 59.038 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 Gene3D G3DSA:3.30.413.10 429 567 6.2E-28 T 29-03-2018 A616_RS31990 10ad944319e4516d446a4ea3d68d30b1 573 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 18 562 1.3E-273 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 Gene3D G3DSA:3.40.50.1970 5 176 1.6E-48 T 29-03-2018 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 SUPERFAMILY SSF56796 6 361 1.19E-109 T 29-03-2018 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 Pfam PF01761 3-dehydroquinate synthase 73 329 1.7E-101 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 PIRSF PIRSF001455 7 364 1.5E-108 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 362 41.656 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 356 3.0E-119 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A616_RS13795 3c48a5a5ad6741fa21aafa4f7ed2f645 366 Gene3D G3DSA:1.20.1090.10 177 365 2.0E-66 T 29-03-2018 A616_RS03690 3344ae35daa156e99a7513ce75031020 266 SUPERFAMILY SSF161098 6 252 9.16E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS03690 3344ae35daa156e99a7513ce75031020 266 Gene3D G3DSA:1.10.3720.10 4 251 3.9E-43 T 29-03-2018 A616_RS03690 3344ae35daa156e99a7513ce75031020 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 249 1.2E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS04070 9e5342d24c9357eb0b250460454b48c3 324 SUPERFAMILY SSF53067 5 322 7.01E-72 T 29-03-2018 A616_RS04070 9e5342d24c9357eb0b250460454b48c3 324 Gene3D G3DSA:3.30.420.40 2 124 5.6E-35 T 29-03-2018 A616_RS04070 9e5342d24c9357eb0b250460454b48c3 324 Gene3D G3DSA:3.30.420.40 125 324 1.8E-60 T 29-03-2018 A616_RS04070 9e5342d24c9357eb0b250460454b48c3 324 Pfam PF00480 ROK family 6 318 5.9E-73 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS04070 9e5342d24c9357eb0b250460454b48c3 324 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 321 3.1E-104 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 A616_RS04070 9e5342d24c9357eb0b250460454b48c3 324 ProSitePatterns PS01125 ROK family signature. 139 166 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS28250 f1d418469d61dbe5d2b36bcc48a0af91 243 Gene3D G3DSA:3.40.50.300 2 241 1.4E-32 T 29-03-2018 A616_RS28250 f1d418469d61dbe5d2b36bcc48a0af91 243 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 7.6E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS28250 f1d418469d61dbe5d2b36bcc48a0af91 243 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 7.6E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS28250 f1d418469d61dbe5d2b36bcc48a0af91 243 Pfam PF02421 Ferrous iron transport protein B 5 159 1.3E-59 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A616_RS28250 f1d418469d61dbe5d2b36bcc48a0af91 243 SUPERFAMILY SSF52540 4 186 8.78E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30695 434f57652861f1d7a37497f232c13759 461 Gene3D G3DSA:1.25.40.10 104 448 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS30695 434f57652861f1d7a37497f232c13759 461 Pfam PF01381 Helix-turn-helix 16 72 6.3E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS30695 434f57652861f1d7a37497f232c13759 461 Gene3D G3DSA:1.10.260.40 7 83 1.1E-9 T 29-03-2018 A616_RS30695 434f57652861f1d7a37497f232c13759 461 SMART SM00530 15 72 1.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS30695 434f57652861f1d7a37497f232c13759 461 SUPERFAMILY SSF47413 12 78 1.72E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS16550 b4272e6064e13661a36d208cfe478435 79 SUPERFAMILY SSF52833 2 78 2.02E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS16550 b4272e6064e13661a36d208cfe478435 79 Gene3D G3DSA:3.40.30.10 1 79 2.6E-10 T 29-03-2018 A616_RS18905 0b60b9447c8d4f1d09c3cee4b28cd722 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 389 4.4E-115 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS18905 0b60b9447c8d4f1d09c3cee4b28cd722 391 SUPERFAMILY SSF53383 34 390 5.06E-90 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS18905 0b60b9447c8d4f1d09c3cee4b28cd722 391 Gene3D G3DSA:3.40.640.10 12 263 9.1E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS18905 0b60b9447c8d4f1d09c3cee4b28cd722 391 Gene3D G3DSA:3.90.1150.10 264 391 9.5E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS18905 0b60b9447c8d4f1d09c3cee4b28cd722 391 PIRSF PIRSF001434 5 391 1.1E-124 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS18905 0b60b9447c8d4f1d09c3cee4b28cd722 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 206 220 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 SUPERFAMILY SSF46785 1 110 2.14E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.6E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 Pfam PF03466 LysR substrate binding domain 89 285 1.4E-32 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 Gene3D G3DSA:3.40.190.10 85 175 3.3E-13 T 29-03-2018 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 Gene3D G3DSA:3.40.190.10 176 256 9.7E-10 T 29-03-2018 A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 Gene3D G3DSA:1.10.10.10 1 83 5.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24995 6c8ecd18d26652b1be9678a3ce1aae66 293 SUPERFAMILY SSF53850 89 287 3.16E-30 T 29-03-2018 A616_RS31535 58fb07be42f3058a76a36fdd5c2b03b8 465 Pfam PF07690 Major Facilitator Superfamily 19 399 7.8E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS31535 58fb07be42f3058a76a36fdd5c2b03b8 465 SUPERFAMILY SSF103473 10 196 2.22E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS31535 58fb07be42f3058a76a36fdd5c2b03b8 465 SUPERFAMILY SSF103473 239 450 2.22E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS31535 58fb07be42f3058a76a36fdd5c2b03b8 465 Gene3D G3DSA:1.20.1250.20 6 204 7.9E-27 T 29-03-2018 A616_RS31535 58fb07be42f3058a76a36fdd5c2b03b8 465 Gene3D G3DSA:1.20.1250.20 251 463 1.7E-11 T 29-03-2018 A616_RS09205 97b0a9c7b3896895f6c24663c40b0db7 224 SMART SM00382 33 221 1.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09205 97b0a9c7b3896895f6c24663c40b0db7 224 SUPERFAMILY SSF52540 6 223 7.59E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09205 97b0a9c7b3896895f6c24663c40b0db7 224 Pfam PF00005 ABC transporter 25 173 3.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09205 97b0a9c7b3896895f6c24663c40b0db7 224 Gene3D G3DSA:3.40.50.300 4 224 7.3E-60 T 29-03-2018 A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 SUPERFAMILY SSF48179 162 282 1.93E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 Gene3D G3DSA:3.40.50.720 3 162 1.2E-33 T 29-03-2018 A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 280 4.6E-23 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 PIRSF PIRSF000103 1 283 3.7E-80 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 4.9E-47 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 SUPERFAMILY SSF51735 3 162 8.45E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS05910 700337a974b58dcccf6bedbb7d14bdd2 283 Gene3D G3DSA:1.10.1040.10 163 283 3.8E-24 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS07685 ada38d224fd27fa047a32bf1d69aca24 259 SMART SM00382 26 215 5.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS07685 ada38d224fd27fa047a32bf1d69aca24 259 Gene3D G3DSA:3.40.50.300 1 249 4.8E-56 T 29-03-2018 A616_RS07685 ada38d224fd27fa047a32bf1d69aca24 259 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS07685 ada38d224fd27fa047a32bf1d69aca24 259 SUPERFAMILY SSF52540 2 228 1.2E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS07685 ada38d224fd27fa047a32bf1d69aca24 259 Pfam PF00005 ABC transporter 18 165 1.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 Pfam PF00549 CoA-ligase 347 506 7.1E-48 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 SUPERFAMILY SSF52210 178 297 2.22E-18 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 Gene3D G3DSA:3.40.50.261 168 337 8.3E-29 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 Gene3D G3DSA:3.40.50.261 338 506 0.16 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 SUPERFAMILY SSF52210 350 510 7.87E-7 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 Gene3D G3DSA:3.40.50.720 28 167 3.0E-6 T 29-03-2018 A616_RS24885 522ea456f2b8128580043315727c3cfa 514 Pfam PF02629 CoA binding domain 189 284 2.2E-16 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS16730 f2b87175de239c1c0bed2c3b320b5076 356 Pfam PF12705 PD-(D/E)XK nuclease superfamily 19 329 3.1E-14 T 29-03-2018 A616_RS16730 f2b87175de239c1c0bed2c3b320b5076 356 Gene3D G3DSA:3.90.320.10 61 238 2.6E-4 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A616_RS00350 8784fcdfbd70da978b1620a95bd12e7a 70 Pfam PF01381 Helix-turn-helix 9 63 3.2E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS00350 8784fcdfbd70da978b1620a95bd12e7a 70 SMART SM00530 8 64 6.1E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS00350 8784fcdfbd70da978b1620a95bd12e7a 70 Gene3D G3DSA:1.10.260.40 7 68 7.8E-10 T 29-03-2018 A616_RS00350 8784fcdfbd70da978b1620a95bd12e7a 70 SUPERFAMILY SSF47413 8 65 8.45E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 SUPERFAMILY SSF50129 6 147 1.13E-26 T 29-03-2018 IPR011032 GroES-like A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 Pfam PF00107 Zinc-binding dehydrogenase 154 288 6.5E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 SUPERFAMILY SSF51735 116 293 5.73E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 Gene3D G3DSA:3.40.50.720 138 312 2.2E-17 T 29-03-2018 A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 1.3E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 Gene3D G3DSA:3.90.180.10 2 137 1.8E-27 T 29-03-2018 A616_RS18435 8487fa0768254c9997ec9967ded4edd5 327 SMART SM00829 13 326 4.9E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS20080 8fba29800b9c4f89c540f095bf520a55 437 Pfam PF01134 Glucose inhibited division protein A 6 368 2.5E-117 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A616_RS20080 8fba29800b9c4f89c540f095bf520a55 437 Gene3D G3DSA:3.50.50.60 2 377 7.7E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS20080 8fba29800b9c4f89c540f095bf520a55 437 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 433 4.9E-236 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 A616_RS20080 8fba29800b9c4f89c540f095bf520a55 437 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A616_RS20080 8fba29800b9c4f89c540f095bf520a55 437 SUPERFAMILY SSF51905 3 367 4.91E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS20080 8fba29800b9c4f89c540f095bf520a55 437 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 37.056 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 A616_RS05595 300cd69c345d8c7f36dd97468147f23b 261 Gene3D G3DSA:2.10.109.10 138 259 2.4E-17 T 29-03-2018 A616_RS05595 300cd69c345d8c7f36dd97468147f23b 261 SUPERFAMILY SSF51306 157 254 9.94E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS05595 300cd69c345d8c7f36dd97468147f23b 261 Gene3D G3DSA:1.10.260.40 3 137 2.4E-6 T 29-03-2018 A616_RS05595 300cd69c345d8c7f36dd97468147f23b 261 Pfam PF00717 Peptidase S24-like 166 239 7.2E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS28725 47254e33448711abe508c53b11c16b1b 215 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 110 208 5.4E-17 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 A616_RS28725 47254e33448711abe508c53b11c16b1b 215 SMART SM00702 36 208 2.0E-42 T 29-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 A616_RS28725 47254e33448711abe508c53b11c16b1b 215 Gene3D G3DSA:2.60.120.620 27 214 2.9E-39 T 29-03-2018 A616_RS14215 78404cd9e5b384257a94e6adb0c56746 288 Gene3D G3DSA:1.10.3720.10 10 274 5.2E-42 T 29-03-2018 A616_RS14215 78404cd9e5b384257a94e6adb0c56746 288 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 11 266 1.4E-95 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 A616_RS14215 78404cd9e5b384257a94e6adb0c56746 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 265 5.7E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14215 78404cd9e5b384257a94e6adb0c56746 288 SUPERFAMILY SSF161098 9 261 3.01E-53 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14215 78404cd9e5b384257a94e6adb0c56746 288 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 10 269 4.6E-124 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 A616_RS15915 30522af4733a4951e223504d0ada430d 539 Gene3D G3DSA:3.40.190.10 173 311 7.0E-35 T 29-03-2018 A616_RS15915 30522af4733a4951e223504d0ada430d 539 Gene3D G3DSA:3.90.76.10 62 172 1.7E-30 T 29-03-2018 A616_RS15915 30522af4733a4951e223504d0ada430d 539 PIRSF PIRSF002741 7 539 1.4E-112 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS15915 30522af4733a4951e223504d0ada430d 539 SUPERFAMILY SSF53850 43 536 1.44E-132 T 29-03-2018 A616_RS15915 30522af4733a4951e223504d0ada430d 539 Gene3D G3DSA:3.10.105.10 312 511 2.1E-56 T 29-03-2018 A616_RS15915 30522af4733a4951e223504d0ada430d 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 460 1.2E-87 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS25245 c0513b84752bfaa1973f302c1198c88b 111 Gene3D G3DSA:3.10.20.30 17 95 4.9E-8 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS25245 c0513b84752bfaa1973f302c1198c88b 111 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 95 4.8E-26 T 29-03-2018 A616_RS25245 c0513b84752bfaa1973f302c1198c88b 111 SUPERFAMILY SSF54292 22 97 3.54E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 4 403 1.5E-91 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 Pfam PF07687 Peptidase dimerisation domain 221 310 1.0E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 Gene3D G3DSA:3.40.630.10 2 298 8.0E-53 T 29-03-2018 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 SUPERFAMILY SSF55031 214 327 6.67E-25 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 Pfam PF01546 Peptidase family M20/M25/M40 101 415 3.7E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 Gene3D G3DSA:3.40.630.10 299 419 4.1E-13 T 29-03-2018 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 SUPERFAMILY SSF53187 3 43 9.92E-62 T 29-03-2018 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 SUPERFAMILY SSF53187 83 229 9.92E-62 T 29-03-2018 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 SUPERFAMILY SSF53187 328 418 9.92E-62 T 29-03-2018 A616_RS04760 1be67ceffc8aead0249682d7b06d0755 419 PIRSF PIRSF005962 2 419 2.1E-107 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 42 58 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 Pfam PF00027 Cyclic nucleotide-binding domain 35 106 4.5E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 Gene3D G3DSA:2.60.120.10 4 150 1.0E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 Gene3D G3DSA:1.10.10.10 151 232 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 SUPERFAMILY SSF46785 151 227 7.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 5.2E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS11040 de5bbc52f710bb2c85f27793934f8a97 232 SUPERFAMILY SSF51206 10 137 8.38E-22 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS26060 dd766867f05b4445ba4b0367c63c5b31 315 SUPERFAMILY SSF161098 68 303 8.5E-64 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS26060 dd766867f05b4445ba4b0367c63c5b31 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 310 2.2E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS26060 dd766867f05b4445ba4b0367c63c5b31 315 Gene3D G3DSA:1.10.3720.10 27 315 2.1E-50 T 29-03-2018 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 5 940 3.0E-219 T 29-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SMART SM00491 791 927 1.4E-30 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Gene3D G3DSA:1.20.5.140 154 171 1.1E-4 T 29-03-2018 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Gene3D G3DSA:3.40.50.300 274 725 1.8E-28 T 29-03-2018 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Pfam PF00270 DEAD/DEAH box helicase 280 490 4.9E-6 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SMART SM00479 3 170 8.8E-52 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Gene3D G3DSA:3.40.50.300 759 938 1.2E-12 T 29-03-2018 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 164 2.3E-28 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Gene3D G3DSA:3.30.420.10 2 153 5.2E-42 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SMART SM00487 272 529 0.0039 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Pfam PF00929 Exonuclease 5 161 1.3E-35 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SUPERFAMILY SSF53098 3 173 2.24E-54 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 Pfam PF13307 Helicase C-terminal domain 775 940 9.4E-35 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SMART SM00488 274 526 9.9E-4 T 29-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SUPERFAMILY SSF52540 748 922 1.19E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SUPERFAMILY SSF52540 287 344 1.19E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SUPERFAMILY SSF52540 697 711 1.19E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13970 60169c51194c3b40a9c720fefa2265ff 967 SUPERFAMILY SSF52540 434 504 1.19E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20160 3af187313795f9fd8f725a709485d2aa 181 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 2 176 30.866 T 29-03-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A616_RS20160 3af187313795f9fd8f725a709485d2aa 181 Gene3D G3DSA:3.90.175.10 83 140 0.0099 T 29-03-2018 A616_RS20160 3af187313795f9fd8f725a709485d2aa 181 SUPERFAMILY SSF56399 5 178 2.83E-56 T 29-03-2018 A616_RS20160 3af187313795f9fd8f725a709485d2aa 181 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 4 168 1.5E-34 T 29-03-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A616_RS13030 ac55fa568aae406576c612da8b2a45d4 238 SUPERFAMILY SSF142823 2 232 3.27E-60 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A616_RS13030 ac55fa568aae406576c612da8b2a45d4 238 Gene3D G3DSA:3.90.1560.10 6 238 7.1E-68 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A616_RS13030 ac55fa568aae406576c612da8b2a45d4 238 Pfam PF04029 2-phosphosulpholactate phosphatase 8 229 2.3E-69 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 Gene3D G3DSA:3.40.50.720 1 239 1.3E-33 T 29-03-2018 A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.5E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.5E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.5E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.8E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 SUPERFAMILY SSF51735 2 231 1.01E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 Pfam PF00106 short chain dehydrogenase 3 193 3.4E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS08515 c9e90070509e3312d7c03640c0b4f41b 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 SMART SM00829 8 344 9.8E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 Pfam PF00107 Zinc-binding dehydrogenase 177 307 1.3E-32 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 Gene3D G3DSA:3.90.180.10 1 159 5.6E-52 T 29-03-2018 A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 SUPERFAMILY SSF51735 138 311 5.46E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 SUPERFAMILY SSF50129 1 171 1.12E-51 T 29-03-2018 IPR011032 GroES-like A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 126 2.1E-31 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS15360 91ea42ecf60659eb6bd627809e1f9aa7 347 Gene3D G3DSA:3.40.50.10730 160 288 6.8E-39 T 29-03-2018 A616_RS12710 b00192feadb23691e1f3cbacc976916f 113 Pfam PF03780 Asp23 family, cell envelope-related function 6 107 3.5E-22 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 A616_RS07815 32e8cc03091ee305a083795585b26f66 480 Gene3D G3DSA:3.90.550.10 42 347 9.5E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS07815 32e8cc03091ee305a083795585b26f66 480 Pfam PF13641 Glycosyltransferase like family 2 56 325 1.3E-21 T 29-03-2018 A616_RS07815 32e8cc03091ee305a083795585b26f66 480 SUPERFAMILY SSF53448 53 361 1.13E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS24795 6c55cd8156b4623ff99f506977fe31d2 58 Pfam PF07235 Protein of unknown function (DUF1427) 5 56 8.3E-15 T 29-03-2018 IPR009872 Protein of unknown function DUF1427 A616_RS24795 6c55cd8156b4623ff99f506977fe31d2 58 TIGRFAM TIGR03510 XapX: XapX domain 4 50 1.9E-17 T 29-03-2018 IPR020017 XapX domain A616_RS21295 5330417f80529fd2b49979c624c451b4 367 Gene3D G3DSA:3.40.50.2000 184 360 6.9E-28 T 29-03-2018 A616_RS21295 5330417f80529fd2b49979c624c451b4 367 Gene3D G3DSA:3.40.50.2000 1 183 1.9E-41 T 29-03-2018 A616_RS21295 5330417f80529fd2b49979c624c451b4 367 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 364 34.453 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS21295 5330417f80529fd2b49979c624c451b4 367 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 346 4.5E-40 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS21295 5330417f80529fd2b49979c624c451b4 367 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 359 4.0E-100 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS21295 5330417f80529fd2b49979c624c451b4 367 SUPERFAMILY SSF53756 1 364 5.83E-108 T 29-03-2018 A616_RS21295 5330417f80529fd2b49979c624c451b4 367 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 4.3E-47 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS02015 2117c1dd184ff680026a92d9364ea50a 171 Pfam PF05163 DinB family 1 165 7.5E-28 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB A616_RS02015 2117c1dd184ff680026a92d9364ea50a 171 Gene3D G3DSA:1.20.120.450 1 170 1.8E-24 T 29-03-2018 A616_RS02015 2117c1dd184ff680026a92d9364ea50a 171 SUPERFAMILY SSF109854 7 162 1.1E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS06455 69227c666d3ebb53999755ca339ef60e 659 Pfam PF12810 Glycine rich protein 25 236 1.1E-26 T 29-03-2018 A616_RS06455 69227c666d3ebb53999755ca339ef60e 659 Gene3D G3DSA:3.40.1850.10 360 458 0.0026 T 29-03-2018 A616_RS06455 69227c666d3ebb53999755ca339ef60e 659 Gene3D G3DSA:2.60.40.10 258 322 1.4E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS06455 69227c666d3ebb53999755ca339ef60e 659 Gene3D G3DSA:2.60.40.10 459 552 0.0023 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS06455 69227c666d3ebb53999755ca339ef60e 659 Gene3D G3DSA:2.40.50.70 323 359 1.6E-5 T 29-03-2018 A616_RS06455 69227c666d3ebb53999755ca339ef60e 659 Gene3D G3DSA:2.40.50.70 219 257 9.5E-5 T 29-03-2018 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 PIRSF PIRSF000105 1 309 6.1E-91 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 SUPERFAMILY SSF51735 2 183 4.81E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 184 5.4E-60 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 184 209 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 285 6.3E-24 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 Gene3D G3DSA:3.40.50.720 1 184 1.3E-47 T 29-03-2018 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 SUPERFAMILY SSF48179 187 285 1.28E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS06960 9fd94e59d9d0c9446fff27d3036d3eb1 310 Gene3D G3DSA:1.10.1040.10 185 290 6.5E-30 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS26910 93ac2ec83db622b8011207d20c077b67 222 Gene3D G3DSA:3.40.50.1000 1 221 5.1E-15 T 29-03-2018 IPR023214 HAD-like domain A616_RS26910 93ac2ec83db622b8011207d20c077b67 222 SUPERFAMILY SSF56784 1 217 4.82E-52 T 29-03-2018 IPR023214 HAD-like domain A616_RS26910 93ac2ec83db622b8011207d20c077b67 222 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 3 218 43.58 T 29-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 A616_RS26910 93ac2ec83db622b8011207d20c077b67 222 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 178 1.8E-18 T 29-03-2018 A616_RS26910 93ac2ec83db622b8011207d20c077b67 222 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 187 4.9E-43 T 29-03-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 A616_RS26910 93ac2ec83db622b8011207d20c077b67 222 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 179 1.8E-30 T 29-03-2018 A616_RS20280 35e99884ddc397b754ab345a57d9a81c 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.929 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A616_RS20280 35e99884ddc397b754ab345a57d9a81c 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 77 1.6E-34 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A616_RS20280 35e99884ddc397b754ab345a57d9a81c 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.7E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS20280 35e99884ddc397b754ab345a57d9a81c 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS20280 35e99884ddc397b754ab345a57d9a81c 77 Gene3D G3DSA:1.10.1200.10 1 77 3.3E-26 T 29-03-2018 A616_RS20280 35e99884ddc397b754ab345a57d9a81c 77 SUPERFAMILY SSF47336 2 76 1.7E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SUPERFAMILY SSF56059 128 399 1.77E-107 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 1054 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.3E-79 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 873 2.8E-38 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Gene3D G3DSA:3.40.50.20 5 117 7.3E-37 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SUPERFAMILY SSF48108 395 548 1.07E-43 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Gene3D G3DSA:3.40.50.20 535 658 1.0E-55 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SUPERFAMILY SSF52440 1 126 6.19E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Gene3D G3DSA:3.40.50.1380 926 1056 1.8E-12 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.4E-61 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SUPERFAMILY SSF52335 945 1057 4.27E-9 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Gene3D G3DSA:3.30.470.20 119 401 9.6E-63 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 541 7.6E-36 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 836 843 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SMART SM01096 420 543 1.1E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SUPERFAMILY SSF56059 669 931 9.37E-86 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SMART SM01209 675 843 1.5E-4 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Gene3D G3DSA:3.30.470.20 662 925 6.0E-56 T 29-03-2018 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Gene3D G3DSA:1.10.1030.10 402 534 1.3E-44 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1064 12.465 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 SUPERFAMILY SSF52440 553 671 4.89E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS29350 7f2263638dcd427291e464fca4732f5a 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS25735 ca98e219fe4e17372faa6b1162c17b36 223 Gene3D G3DSA:2.170.16.10 21 107 8.6E-21 T 29-03-2018 A616_RS25735 ca98e219fe4e17372faa6b1162c17b36 223 SUPERFAMILY SSF51294 32 107 7.06E-16 T 29-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS25735 ca98e219fe4e17372faa6b1162c17b36 223 Pfam PF07591 Pretoxin HINT domain 32 107 2.4E-19 T 29-03-2018 A616_RS13575 1012b60595e99f078d46605bf2538b22 225 Gene3D G3DSA:3.10.350.10 168 225 2.7E-5 T 29-03-2018 A616_RS13575 1012b60595e99f078d46605bf2538b22 225 SMART SM00257 175 222 8.2E-4 T 29-03-2018 IPR018392 LysM domain A616_RS13575 1012b60595e99f078d46605bf2538b22 225 SUPERFAMILY SSF54106 174 222 1.7E-5 T 29-03-2018 IPR018392 LysM domain A616_RS13575 1012b60595e99f078d46605bf2538b22 225 Pfam PF01476 LysM domain 176 222 2.4E-6 T 29-03-2018 IPR018392 LysM domain A616_RS20180 ff7bc58c1d75ee788bbbb2b8539197ab 258 Pfam PF10127 Predicted nucleotidyltransferase 2 248 9.2E-89 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted A616_RS20180 ff7bc58c1d75ee788bbbb2b8539197ab 258 Gene3D G3DSA:3.30.460.10 1 224 5.0E-5 T 29-03-2018 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 273 1.0E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 Gene3D G3DSA:3.30.565.10 269 431 3.6E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02100 5be9954decd966745525f4aef0fa46da 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 428 9.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 409 9.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 9.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 9.0E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 SMART SM00388 207 274 1.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 Gene3D G3DSA:1.10.287.130 215 268 1.5E-14 T 29-03-2018 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 SUPERFAMILY SSF55874 263 429 2.1E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02100 5be9954decd966745525f4aef0fa46da 431 Gene3D G3DSA:3.30.450.20 6 214 8.6E-4 T 29-03-2018 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 429 1.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02100 5be9954decd966745525f4aef0fa46da 431 SUPERFAMILY SSF47384 197 275 2.16E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02100 5be9954decd966745525f4aef0fa46da 431 SMART SM00387 319 431 1.3E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 22.59 T 29-03-2018 IPR023460 Ribosomal protein L7Ae, putative A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 Gene3D G3DSA:3.30.1330.30 2 84 7.7E-21 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 PRINTS PR00884 Ribosomal protein HS6 signature 20 30 5.2E-5 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 PRINTS PR00884 Ribosomal protein HS6 signature 56 66 5.2E-5 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 PRINTS PR00884 Ribosomal protein HS6 signature 70 84 5.2E-5 T 29-03-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 SUPERFAMILY SSF55315 5 83 6.56E-22 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like A616_RS01355 c0a6d0b50ebc8150ce4a96e761fdd62b 84 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 84 9.3E-19 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A616_RS17685 6f3ba954a647c29fc66b52e37fa72ed1 145 Pfam PF12802 MarR family 32 83 3.6E-11 T 29-03-2018 A616_RS17685 6f3ba954a647c29fc66b52e37fa72ed1 145 SUPERFAMILY SSF46785 4 138 2.08E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17685 6f3ba954a647c29fc66b52e37fa72ed1 145 Gene3D G3DSA:1.10.10.10 2 145 2.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17685 6f3ba954a647c29fc66b52e37fa72ed1 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS17685 6f3ba954a647c29fc66b52e37fa72ed1 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS17685 6f3ba954a647c29fc66b52e37fa72ed1 145 SMART SM00347 27 124 1.7E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS05935 0f233a5e90aedc205ee43ec04ff4d718 336 SUPERFAMILY SSF52540 30 248 1.33E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05935 0f233a5e90aedc205ee43ec04ff4d718 336 SMART SM00382 47 232 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS05935 0f233a5e90aedc205ee43ec04ff4d718 336 Gene3D G3DSA:3.40.50.300 1 297 5.1E-57 T 29-03-2018 A616_RS05935 0f233a5e90aedc205ee43ec04ff4d718 336 Pfam PF00005 ABC transporter 39 182 1.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Pfam PF02225 PA domain 330 407 1.4E-10 T 29-03-2018 IPR003137 PA domain A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 PRINTS PR00723 Subtilisin serine protease family (S8) signature 478 494 1.4E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 117 1.4E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 PRINTS PR00723 Subtilisin serine protease family (S8) signature 153 166 1.4E-17 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 103 114 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Gene3D G3DSA:2.60.40.1710 565 695 1.7E-23 T 29-03-2018 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 479 489 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Pfam PF00082 Subtilase family 98 553 1.1E-58 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Pfam PF06280 Fn3-like domain 576 685 2.1E-16 T 29-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 SUPERFAMILY SSF52025 329 495 2.35E-18 T 29-03-2018 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 SUPERFAMILY SSF52743 82 292 3.67E-67 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 SUPERFAMILY SSF52743 441 563 3.67E-67 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Gene3D G3DSA:2.60.40.1310 998 1089 0.002 T 29-03-2018 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Gene3D G3DSA:2.60.40.1310 832 899 0.11 T 29-03-2018 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Gene3D G3DSA:3.40.50.200 82 564 4.4E-73 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS09800 fc2366408344e28623d9a89af745a37d 1243 Gene3D G3DSA:2.60.40.10 1150 1239 0.0066 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 SUPERFAMILY SSF53474 2 255 1.36E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 Pfam PF00561 alpha/beta hydrolase fold 15 118 8.4E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 Gene3D G3DSA:3.40.50.1820 1 265 7.3E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00412 Epoxide hydrolase signature 20 38 7.7E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00412 Epoxide hydrolase signature 200 216 7.7E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00412 Epoxide hydrolase signature 232 254 7.7E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 3.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 3.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 3.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS28150 ed50fe6cd058ccf95874003b93dd1a4a 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 3.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS19325 049289a93ff3801919faaa95f2f94b31 57 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 26 55 1.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS25035 a2e6f33eef7d0b0fc81b066025c2ba5e 385 Gene3D G3DSA:3.40.710.10 44 384 1.3E-75 T 29-03-2018 A616_RS25035 a2e6f33eef7d0b0fc81b066025c2ba5e 385 Pfam PF00144 Beta-lactamase 60 354 4.2E-64 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS25035 a2e6f33eef7d0b0fc81b066025c2ba5e 385 SUPERFAMILY SSF56601 53 373 4.99E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS21035 4fb6e8789245b2ace7e83210705a1567 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 125 7.1E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS21035 4fb6e8789245b2ace7e83210705a1567 133 Gene3D G3DSA:3.10.180.10 2 131 1.8E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS21035 4fb6e8789245b2ace7e83210705a1567 133 SUPERFAMILY SSF54593 3 131 2.55E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 SUPERFAMILY SSF46785 2 139 1.8E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 Pfam PF01047 MarR family 31 88 1.5E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 Gene3D G3DSA:1.10.10.10 1 140 4.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 ProSitePatterns PS01117 MarR-type HTH domain signature. 63 97 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31530 0577131d1028b5eec3dbccfeaa893c04 141 SMART SM00347 24 124 1.2E-26 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS20015 2b216fc9ec61d50bc9a8bbd60bc3037b 300 Pfam PF03448 MgtE intracellular N domain 136 190 4.4E-7 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A616_RS20015 2b216fc9ec61d50bc9a8bbd60bc3037b 300 Gene3D G3DSA:1.20.5.730 74 141 1.6E-7 T 29-03-2018 A616_RS20015 2b216fc9ec61d50bc9a8bbd60bc3037b 300 Gene3D G3DSA:1.10.220.30 219 298 2.5E-5 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20015 2b216fc9ec61d50bc9a8bbd60bc3037b 300 Gene3D G3DSA:1.10.220.30 142 218 3.6E-11 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A616_RS20015 2b216fc9ec61d50bc9a8bbd60bc3037b 300 SUPERFAMILY SSF158791 138 194 7.46E-8 T 29-03-2018 A616_RS01990 4a1a8192ca06b167ecf7d2c4f9bf96f8 98 Gene3D G3DSA:2.20.25.10 2 92 1.1E-6 T 29-03-2018 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 Pfam PF00005 ABC transporter 25 183 2.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 Pfam PF00005 ABC transporter 384 535 1.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 587 619 7.8E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 296 4.7E-12 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 Gene3D G3DSA:3.40.50.300 1 332 1.6E-83 T 29-03-2018 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 Gene3D G3DSA:3.40.50.300 359 658 1.5E-75 T 29-03-2018 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 SUPERFAMILY SSF52540 4 254 9.97E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 SUPERFAMILY SSF52540 362 607 2.01E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 SMART SM00382 392 585 1.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 SMART SM00382 33 233 2.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02000 3e46d5147752349c6ad246f90e9655c8 667 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 2.6E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 SUPERFAMILY SSF56601 212 317 6.99E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 SUPERFAMILY SSF56601 359 665 6.99E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 SUPERFAMILY SSF56519 48 260 1.29E-33 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 Pfam PF00905 Penicillin binding protein transpeptidase domain 294 660 9.3E-54 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 Gene3D G3DSA:3.40.710.10 261 667 1.4E-75 T 29-03-2018 A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 Gene3D G3DSA:3.90.1310.10 24 260 6.9E-42 T 29-03-2018 A616_RS25920 c30eac1e7a37a391684e5209346247d7 670 Pfam PF03717 Penicillin-binding Protein dimerisation domain 55 246 9.1E-32 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 SMART SM01211 1 220 2.7E-140 T 29-03-2018 A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 SUPERFAMILY SSF52317 1 219 1.62E-79 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 4.3E-96 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 45.463 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 PIRSF PIRSF001586 1 223 7.0E-91 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 Gene3D G3DSA:3.40.50.880 1 222 5.4E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS03555 7adbd4e963c9869498844a5d476f4fdb 230 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 206 2.6E-47 T 29-03-2018 A616_RS26260 17d78d8439fcc4e880eae1c76ad7bad9 158 Pfam PF00293 NUDIX domain 11 121 1.8E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS26260 17d78d8439fcc4e880eae1c76ad7bad9 158 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS26260 17d78d8439fcc4e880eae1c76ad7bad9 158 PRINTS PR00502 NUDIX hydrolase family signature 34 48 3.4E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS26260 17d78d8439fcc4e880eae1c76ad7bad9 158 PRINTS PR00502 NUDIX hydrolase family signature 48 63 3.4E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS26260 17d78d8439fcc4e880eae1c76ad7bad9 158 SUPERFAMILY SSF55811 7 134 1.08E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS26260 17d78d8439fcc4e880eae1c76ad7bad9 158 Gene3D G3DSA:3.90.79.10 2 140 2.0E-27 T 29-03-2018 A616_RS29860 fb95376320890e19e520f5a996c3334a 137 Pfam PF12838 4Fe-4S dicluster domain 45 102 1.7E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A616_RS29860 fb95376320890e19e520f5a996c3334a 137 Gene3D G3DSA:3.30.70.20 95 137 2.5E-6 T 29-03-2018 A616_RS29860 fb95376320890e19e520f5a996c3334a 137 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS29860 fb95376320890e19e520f5a996c3334a 137 Gene3D G3DSA:3.30.70.20 52 94 9.9E-15 T 29-03-2018 A616_RS29860 fb95376320890e19e520f5a996c3334a 137 SUPERFAMILY SSF54862 24 126 1.59E-23 T 29-03-2018 A616_RS29860 fb95376320890e19e520f5a996c3334a 137 Gene3D G3DSA:1.10.1060.10 17 51 0.017 T 29-03-2018 A616_RS29860 fb95376320890e19e520f5a996c3334a 137 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 121 1.3E-33 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS05140 728a47b47d9125e1106cdf14c9f41427 417 Gene3D G3DSA:1.20.1250.20 9 197 2.5E-29 T 29-03-2018 A616_RS05140 728a47b47d9125e1106cdf14c9f41427 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS05140 728a47b47d9125e1106cdf14c9f41427 417 SUPERFAMILY SSF103473 14 410 1.1E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS05140 728a47b47d9125e1106cdf14c9f41427 417 Pfam PF07690 Major Facilitator Superfamily 263 404 2.3E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05140 728a47b47d9125e1106cdf14c9f41427 417 Pfam PF07690 Major Facilitator Superfamily 19 244 2.2E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05140 728a47b47d9125e1106cdf14c9f41427 417 Gene3D G3DSA:1.20.1250.20 202 410 1.0E-21 T 29-03-2018 A616_RS09500 39a5905560d1a39d787df93acebe16d2 448 Pfam PF02386 Cation transport protein 40 435 4.6E-58 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A616_RS09500 39a5905560d1a39d787df93acebe16d2 448 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 31 419 4.4E-109 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 449 4.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 450 6.1E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 SMART SM00387 344 452 1.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 SUPERFAMILY SSF55874 292 450 2.62E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS31025 f3e27e857d3dc48718bd63247e44efe6 459 Gene3D G3DSA:3.30.565.10 263 450 8.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS18055 b72ebaf3054f9a3579e883b07271ac24 385 Gene3D G3DSA:1.25.40.10 284 379 3.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS18055 b72ebaf3054f9a3579e883b07271ac24 385 Gene3D G3DSA:3.40.630.30 88 279 1.2E-12 T 29-03-2018 A616_RS18055 b72ebaf3054f9a3579e883b07271ac24 385 SUPERFAMILY SSF55729 164 271 2.3E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS18055 b72ebaf3054f9a3579e883b07271ac24 385 Pfam PF12746 GNAT acetyltransferase 23 272 3.2E-16 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like A616_RS18055 b72ebaf3054f9a3579e883b07271ac24 385 SUPERFAMILY SSF81901 287 358 1.96E-8 T 29-03-2018 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 SUPERFAMILY SSF144052 3 408 2.62E-151 T 29-03-2018 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 Gene3D G3DSA:3.40.1830.10 4 174 1.1E-62 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 1.8E-78 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS14710 6bb761de4d1c853234393d84fb4b9b41 408 Pfam PF02073 Thermophilic metalloprotease (M29) 5 407 4.4E-176 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS10625 4f34be7568f0987de74da96ea86bbad1 342 SUPERFAMILY SSF56112 18 301 1.5E-29 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS10625 4f34be7568f0987de74da96ea86bbad1 342 Pfam PF01636 Phosphotransferase enzyme family 29 248 7.5E-11 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS10625 4f34be7568f0987de74da96ea86bbad1 342 Gene3D G3DSA:3.30.200.20 2 91 7.4E-6 T 29-03-2018 A616_RS10625 4f34be7568f0987de74da96ea86bbad1 342 Gene3D G3DSA:3.90.1200.10 92 325 2.4E-17 T 29-03-2018 A616_RS07710 4305f88951e206dc2a510cffe17647eb 231 Gene3D G3DSA:3.60.15.10 1 231 4.6E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07710 4305f88951e206dc2a510cffe17647eb 231 SMART SM00849 8 194 9.0E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS07710 4305f88951e206dc2a510cffe17647eb 231 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 230 37.158 T 29-03-2018 IPR022877 Protein of unknown funcion UPF0173 A616_RS07710 4305f88951e206dc2a510cffe17647eb 231 Pfam PF13483 Beta-lactamase superfamily domain 4 194 6.3E-24 T 29-03-2018 A616_RS07710 4305f88951e206dc2a510cffe17647eb 231 SUPERFAMILY SSF56281 1 216 5.37E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 SUPERFAMILY SSF55920 136 361 3.01E-74 T 29-03-2018 IPR000994 Peptidase M24 A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 Pfam PF00557 Metallopeptidase family M24 144 345 5.1E-59 T 29-03-2018 IPR000994 Peptidase M24 A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 134 6.6E-24 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 SUPERFAMILY SSF53092 1 133 6.28E-30 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 Gene3D G3DSA:3.40.350.10 1 132 4.8E-24 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 Gene3D G3DSA:3.90.230.10 134 362 1.2E-72 T 29-03-2018 A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 PRINTS PR00599 Methionine aminopeptidase-1 signature 215 231 4.2E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS12485 c1b635618c68bfa273983b9fa9d45f4d 362 PRINTS PR00599 Methionine aminopeptidase-1 signature 313 325 4.2E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS20970 6c887a15d3e90f30e4406d6182ff2a46 158 Pfam PF13673 Acetyltransferase (GNAT) domain 48 144 4.4E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS20970 6c887a15d3e90f30e4406d6182ff2a46 158 SUPERFAMILY SSF55729 2 143 5.32E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS20970 6c887a15d3e90f30e4406d6182ff2a46 158 Gene3D G3DSA:3.40.630.30 1 155 3.1E-14 T 29-03-2018 A616_RS31515 cccf1d6fa4b95809f3ec48541ae2b085 461 Pfam PF02347 Glycine cleavage system P-protein 10 455 2.5E-68 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A616_RS31515 cccf1d6fa4b95809f3ec48541ae2b085 461 Gene3D G3DSA:3.90.1150.10 355 461 1.1E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS31515 cccf1d6fa4b95809f3ec48541ae2b085 461 SUPERFAMILY SSF53383 9 461 3.33E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS31515 cccf1d6fa4b95809f3ec48541ae2b085 461 Gene3D G3DSA:3.40.640.10 90 354 3.3E-19 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 Pfam PF02445 Quinolinate synthetase A protein 19 310 5.6E-121 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 14 311 5.8E-114 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 Gene3D G3DSA:3.40.50.10800 103 181 3.0E-24 T 29-03-2018 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 SUPERFAMILY SSF142754 15 310 1.57E-119 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 Hamap MF_00568 Quinolinate synthase A [nadA]. 14 311 43.951 T 29-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 Gene3D G3DSA:3.40.50.10800 182 293 4.5E-33 T 29-03-2018 A616_RS00820 8f778a61da3f8dce7a5a392f1999ca0b 314 Gene3D G3DSA:3.40.50.10800 15 102 9.7E-23 T 29-03-2018 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 Gene3D G3DSA:1.20.210.10 46 560 3.7E-192 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 SUPERFAMILY SSF81442 48 557 7.19E-178 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 59 505 2.3E-146 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 50 75 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 4.8E-92 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS07065 8778ad612d947fc4fa921b36724d1369 656 Gene3D G3DSA:1.10.287.70 575 642 3.7E-18 T 29-03-2018 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 Gene3D G3DSA:1.10.287.950 89 202 9.0E-9 T 29-03-2018 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 SUPERFAMILY SSF58104 180 449 2.09E-63 T 29-03-2018 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 SUPERFAMILY SSF58104 117 147 2.09E-63 T 29-03-2018 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 Gene3D G3DSA:1.10.287.950 203 393 2.0E-45 T 29-03-2018 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 Gene3D G3DSA:1.10.287.950 394 449 0.21 T 29-03-2018 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 SMART SM00283 174 449 4.4E-53 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 Pfam PF00672 HAMP domain 94 141 3.6E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 220 396 5.1E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS02260 27ab8ee3f5a707e76ff3b0f1d5be68fb 450 SMART SM00304 92 145 1.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS29620 cb59d2e0001f4c4131a37e9de9ce9a58 338 Pfam PF01522 Polysaccharide deacetylase 132 290 4.1E-21 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS29620 cb59d2e0001f4c4131a37e9de9ce9a58 338 Gene3D G3DSA:3.20.20.370 95 335 1.3E-34 T 29-03-2018 A616_RS29620 cb59d2e0001f4c4131a37e9de9ce9a58 338 SUPERFAMILY SSF88713 243 297 1.33E-28 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS29620 cb59d2e0001f4c4131a37e9de9ce9a58 338 SUPERFAMILY SSF88713 93 216 1.33E-28 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 Pfam PF02142 MGS-like domain 15 107 2.9E-16 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 35.777 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 Gene3D G3DSA:3.40.50.1380 1 134 4.0E-35 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 SMART SM00851 14 107 1.3E-22 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 PIRSF PIRSF006614 1 136 8.8E-59 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 SUPERFAMILY SSF52335 2 131 1.31E-51 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS13925 68db048b26a6c03a7cc4f5d77e735369 136 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 121 3.7E-54 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 SUPERFAMILY SSF101821 70 179 1.98E-31 T 29-03-2018 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 Gene3D G3DSA:3.40.630.10 169 358 6.4E-42 T 29-03-2018 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 SUPERFAMILY SSF53187 4 80 7.29E-66 T 29-03-2018 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 SUPERFAMILY SSF53187 171 354 7.29E-66 T 29-03-2018 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 Pfam PF05343 M42 glutamyl aminopeptidase 45 339 8.5E-102 T 29-03-2018 IPR008007 Peptidase M42 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 Gene3D G3DSA:2.40.30.40 69 161 2.2E-32 T 29-03-2018 IPR023367 Peptidase M42, domain 2 A616_RS24025 9dec06dce3dc05e9143c1bc7fb86f88c 358 PIRSF PIRSF001123 1 358 1.0E-132 T 29-03-2018 IPR008007 Peptidase M42 A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 SMART SM00849 20 219 6.2E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 SUPERFAMILY SSF56281 9 424 9.01E-94 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 Pfam PF00753 Metallo-beta-lactamase superfamily 22 166 1.3E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 1.0E-191 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 363 409 2.6E-9 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 Gene3D G3DSA:3.60.15.10 2 448 1.0E-64 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 PIRSF PIRSF004803 1 555 2.8E-230 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A616_RS12830 1e272495269aef4d79fad8315e4ba71b 555 Hamap MF_01491 Ribonuclease J [rnj]. 3 555 45.235 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A616_RS04600 836e8ecb4af4b70ca02e644e27767c95 255 Gene3D G3DSA:2.30.30.410 25 125 5.9E-11 T 29-03-2018 A616_RS04600 836e8ecb4af4b70ca02e644e27767c95 255 Pfam PF00413 Matrixin 196 253 3.4E-6 T 29-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 A616_RS04600 836e8ecb4af4b70ca02e644e27767c95 255 SUPERFAMILY SSF55486 130 254 1.34E-15 T 29-03-2018 A616_RS04600 836e8ecb4af4b70ca02e644e27767c95 255 Gene3D G3DSA:3.40.390.10 126 255 6.5E-13 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 SUPERFAMILY SSF53067 4 313 7.2E-24 T 29-03-2018 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 Pfam PF00814 Glycoprotease family 58 307 1.4E-33 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 Gene3D G3DSA:3.30.420.40 3 148 9.5E-14 T 29-03-2018 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 Gene3D G3DSA:3.30.420.40 149 290 1.9E-15 T 29-03-2018 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 161 182 2.2E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 2.2E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 6 19 2.2E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS13120 f83c453d4c2f1c7be9f2c26fb54f7cc5 320 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 99 118 2.2E-13 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 Gene3D G3DSA:3.60.21.10 30 367 4.8E-76 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 Gene3D G3DSA:3.90.780.10 368 622 2.6E-57 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 TIGRFAM TIGR01390 CycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase 39 658 9.7E-271 T 29-03-2018 IPR006294 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase GO:0008663|GO:0009117 KEGG: 00230+3.1.4.16+3.1.3.6|KEGG: 00240+3.1.4.16+3.1.3.6 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 Pfam PF00149 Calcineurin-like phosphoesterase 41 283 9.1E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 SUPERFAMILY SSF56300 35 375 3.2E-85 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 Pfam PF02872 5'-nucleotidase, C-terminal domain 380 575 1.3E-20 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 SUPERFAMILY SSF55816 379 614 5.76E-44 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 ProSitePatterns PS00786 5'-nucleotidase signature 2. 126 137 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 PRINTS PR01607 Apyrase family signature 449 472 7.5E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 PRINTS PR01607 Apyrase family signature 550 569 7.5E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 PRINTS PR01607 Apyrase family signature 238 255 7.5E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 PRINTS PR01607 Apyrase family signature 266 289 7.5E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 PRINTS PR01607 Apyrase family signature 38 56 7.5E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10630 ea6f6901ad494623ce831abd8f9e9df0 662 PRINTS PR01607 Apyrase family signature 306 326 7.5E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A616_RS10665 5a6958cbbd023974fe76ec8bfef34590 72 Pfam PF11146 Protein of unknown function (DUF2905) 5 68 9.3E-26 T 29-03-2018 IPR021320 Protein of unknown function DUF2905 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 Gene3D G3DSA:3.50.50.60 10 269 3.3E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 3.0E-6 T 29-03-2018 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 3.0E-6 T 29-03-2018 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 12 625 7.4E-286 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 Pfam PF01134 Glucose inhibited division protein A 13 402 3.8E-168 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 SUPERFAMILY SSF51905 102 265 1.61E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 SUPERFAMILY SSF51905 11 71 1.61E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 Pfam PF13932 GidA associated domain 405 620 1.2E-77 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 372 395 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 10 628 42.448 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.4E-5 T 29-03-2018 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 2.4E-5 T 29-03-2018 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 SMART SM01228 550 621 5.2E-40 T 29-03-2018 A616_RS32280 793188551ce53c0f9beadc56e840a44b 632 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 277 291 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A616_RS15070 8722a297fd64d666d5de3bec3540a0a5 222 Gene3D G3DSA:1.10.3720.10 1 217 3.4E-34 T 29-03-2018 A616_RS15070 8722a297fd64d666d5de3bec3540a0a5 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 215 1.3E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15070 8722a297fd64d666d5de3bec3540a0a5 222 SUPERFAMILY SSF161098 8 205 2.62E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.0E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 6.8E-55 T 29-03-2018 A616_RS31080 8855babc8c0086b912f77806425876a7 255 Gene3D G3DSA:3.40.50.720 41 255 1.1E-58 T 29-03-2018 A616_RS31080 8855babc8c0086b912f77806425876a7 255 Gene3D G3DSA:3.40.50.720 1 40 1.7E-10 T 29-03-2018 A616_RS31080 8855babc8c0086b912f77806425876a7 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0015 T 29-03-2018 A616_RS31080 8855babc8c0086b912f77806425876a7 255 SUPERFAMILY SSF51735 5 255 9.2E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31080 8855babc8c0086b912f77806425876a7 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS22530 c52daf0364a341e936edd066cfb5ec6a 305 Gene3D G3DSA:3.90.850.10 38 305 3.0E-67 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS22530 c52daf0364a341e936edd066cfb5ec6a 305 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 303 8.1E-62 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS22530 c52daf0364a341e936edd066cfb5ec6a 305 SUPERFAMILY SSF56529 75 303 5.76E-73 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS18700 eb9f6b59bca3171fdd838495ba1ee60b 496 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 37 459 2.5E-107 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 A616_RS20485 44fd319dd87788e3d8868e69a732e1d0 273 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 120 248 5.1E-46 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A616_RS20485 44fd319dd87788e3d8868e69a732e1d0 273 Gene3D G3DSA:3.30.1380.10 88 258 4.8E-38 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS20485 44fd319dd87788e3d8868e69a732e1d0 273 SUPERFAMILY SSF55166 104 255 3.66E-38 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS05590 61c09803a3e7bf76ce364282289a0f20 357 Pfam PF08808 RES domain 190 330 7.1E-17 T 29-03-2018 IPR014914 RES domain A616_RS05590 61c09803a3e7bf76ce364282289a0f20 357 SMART SM00953 190 338 1.6E-5 T 29-03-2018 IPR014914 RES domain A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 Gene3D G3DSA:3.40.50.720 1 152 2.0E-22 T 29-03-2018 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 PIRSF PIRSF000193 1 263 3.4E-64 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 218 240 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 157 244 2.4E-15 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 SUPERFAMILY SSF51735 1 151 1.25E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 263 16.592 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 Gene3D G3DSA:1.10.3730.10 154 264 1.3E-17 T 29-03-2018 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 SUPERFAMILY SSF48179 157 249 3.23E-15 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS05915 de6897736ac9b87cef7a9ef582ec6c31 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 95 7.8E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A616_RS26570 48cbcb1282d7cb285935a5b426a54133 310 SUPERFAMILY SSF46626 65 175 1.43E-26 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS26570 48cbcb1282d7cb285935a5b426a54133 310 Gene3D G3DSA:1.10.760.10 10 178 6.7E-27 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS26570 48cbcb1282d7cb285935a5b426a54133 310 Pfam PF00034 Cytochrome c 194 277 1.5E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS26570 48cbcb1282d7cb285935a5b426a54133 310 Gene3D G3DSA:1.10.760.10 179 283 1.6E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS26570 48cbcb1282d7cb285935a5b426a54133 310 SUPERFAMILY SSF46626 190 284 3.3E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 SMART SM00382 29 211 1.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 Pfam PF13732 Domain of unknown function (DUF4162) 217 305 5.7E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 Gene3D G3DSA:3.40.50.300 1 223 4.4E-66 T 29-03-2018 A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 SUPERFAMILY SSF52540 3 223 6.99E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 Pfam PF00005 ABC transporter 20 163 1.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS04395 71b9ef408f991830ee2c8beac083a6ef 312 Gene3D G3DSA:3.30.1360.60 224 282 0.0019 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A616_RS16145 7f5a81af195132533c6a7db555167135 213 SUPERFAMILY SSF49695 32 117 7.3E-9 T 29-03-2018 IPR011024 Gamma-crystallin-related A616_RS16145 7f5a81af195132533c6a7db555167135 213 SUPERFAMILY SSF49695 128 208 3.41E-9 T 29-03-2018 IPR011024 Gamma-crystallin-related A616_RS16145 7f5a81af195132533c6a7db555167135 213 Gene3D G3DSA:2.60.20.10 34 124 6.7E-11 T 29-03-2018 A616_RS16145 7f5a81af195132533c6a7db555167135 213 Gene3D G3DSA:2.60.20.10 126 213 5.5E-13 T 29-03-2018 A616_RS12805 2100eb1163897950be225ca52dfd7ab3 249 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 34 242 9.1E-20 T 29-03-2018 A616_RS18755 34f92aa32ff7c08e7965e69e9f1886cf 193 SUPERFAMILY SSF102405 1 179 1.01E-55 T 29-03-2018 A616_RS18755 34f92aa32ff7c08e7965e69e9f1886cf 193 Gene3D G3DSA:3.40.50.450 1 193 8.0E-54 T 29-03-2018 A616_RS18755 34f92aa32ff7c08e7965e69e9f1886cf 193 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 4.8E-61 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG A616_RS18755 34f92aa32ff7c08e7965e69e9f1886cf 193 Pfam PF03641 Possible lysine decarboxylase 46 175 1.6E-38 T 29-03-2018 IPR031100 LOG family A616_RS04445 fa00663d0251520782e99880ecd0fe41 360 Gene3D G3DSA:3.40.50.2000 1 183 1.9E-29 T 29-03-2018 A616_RS04445 fa00663d0251520782e99880ecd0fe41 360 Gene3D G3DSA:3.40.50.2000 184 341 2.5E-24 T 29-03-2018 A616_RS04445 fa00663d0251520782e99880ecd0fe41 360 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 142 7.5E-34 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS04445 fa00663d0251520782e99880ecd0fe41 360 SUPERFAMILY SSF53756 2 341 7.49E-85 T 29-03-2018 A616_RS04445 fa00663d0251520782e99880ecd0fe41 360 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 353 26.346 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS04445 fa00663d0251520782e99880ecd0fe41 360 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 340 2.9E-26 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS21915 4464d0decc458034b46ba952f6523101 117 SUPERFAMILY SSF89360 1 94 5.49E-29 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS21915 4464d0decc458034b46ba952f6523101 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 87 104 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A616_RS21915 4464d0decc458034b46ba952f6523101 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 101 6.3E-20 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS21915 4464d0decc458034b46ba952f6523101 117 Gene3D G3DSA:2.60.300.12 1 109 6.4E-35 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS21915 4464d0decc458034b46ba952f6523101 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 105 1.4E-34 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 SUPERFAMILY SSF46955 3 107 1.43E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 SMART SM00422 3 72 1.8E-25 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 Pfam PF13411 MerR HTH family regulatory protein 3 71 1.1E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 Gene3D G3DSA:1.10.1660.10 1 144 3.7E-37 T 29-03-2018 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 4.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 4.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 4.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 Gene3D G3DSA:1.10.490.50 164 252 1.2E-27 T 29-03-2018 A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 SUPERFAMILY SSF89082 165 250 1.44E-27 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain A616_RS21830 df540ad4144a5909f9303a55ec9a5490 252 Pfam PF07739 TipAS antibiotic-recognition domain 135 249 2.5E-35 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain A616_RS12650 3bcf6ed70c34218920349fcc3abcd5fb 45 Pfam PF08970 Sporulation inhibitor A 2 40 5.8E-15 T 29-03-2018 IPR015064 Sporulation inhibitor A A616_RS12650 3bcf6ed70c34218920349fcc3abcd5fb 45 SUPERFAMILY SSF100985 2 41 1.26E-11 T 29-03-2018 IPR015064 Sporulation inhibitor A A616_RS12650 3bcf6ed70c34218920349fcc3abcd5fb 45 Gene3D G3DSA:1.10.287.1100 4 36 1.0E-15 T 29-03-2018 IPR015064 Sporulation inhibitor A A616_RS09550 cd89c14a3ee7c29296ff85129406e6a2 376 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 8 373 1.0E-83 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS09550 cd89c14a3ee7c29296ff85129406e6a2 376 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 210 372 1.8E-29 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS06760 05aa862605b1e3e73924024e03551069 325 Gene3D G3DSA:3.90.1200.10 116 325 5.1E-18 T 29-03-2018 A616_RS06760 05aa862605b1e3e73924024e03551069 325 Gene3D G3DSA:3.30.200.20 5 114 4.5E-14 T 29-03-2018 A616_RS06760 05aa862605b1e3e73924024e03551069 325 Pfam PF01636 Phosphotransferase enzyme family 39 273 2.5E-20 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS06760 05aa862605b1e3e73924024e03551069 325 SUPERFAMILY SSF56112 11 302 1.46E-43 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS05375 043beabc49d11dcaf59fd54d96050092 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 23 224 1.6E-69 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS05375 043beabc49d11dcaf59fd54d96050092 293 PIRSF PIRSF006483 5 292 2.5E-98 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS05375 043beabc49d11dcaf59fd54d96050092 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 230 284 6.2E-23 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 3.9E-52 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 PIRSF PIRSF002191 1 115 1.8E-52 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 SUPERFAMILY SSF50104 1 114 1.91E-49 T 29-03-2018 IPR008991 Translation protein SH3-like domain A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.952 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20220 27f42f794a866604d2fb77f6e74ba6af 115 Pfam PF01245 Ribosomal protein L19 4 112 1.3E-52 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS16225 1a6e83a4942ff848c82ec962afbe2ac3 488 SUPERFAMILY SSF53720 11 487 3.27E-168 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS16225 1a6e83a4942ff848c82ec962afbe2ac3 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS16225 1a6e83a4942ff848c82ec962afbe2ac3 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A616_RS16225 1a6e83a4942ff848c82ec962afbe2ac3 488 Gene3D G3DSA:3.40.309.10 275 470 1.5E-75 T 29-03-2018 A616_RS16225 1a6e83a4942ff848c82ec962afbe2ac3 488 Pfam PF00171 Aldehyde dehydrogenase family 23 484 2.3E-175 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS16225 1a6e83a4942ff848c82ec962afbe2ac3 488 Gene3D G3DSA:3.40.605.10 1 274 1.6E-93 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS08880 373f17f4020d5c5caf94b08cd566c58c 193 Gene3D G3DSA:2.60.60.30 19 187 2.4E-64 T 29-03-2018 A616_RS08880 373f17f4020d5c5caf94b08cd566c58c 193 Pfam PF02342 TerD domain 1 188 5.1E-84 T 29-03-2018 IPR003325 TerD domain GO:0006950 A616_RS21775 1f8181a0b976cf7aef519226150b8a42 434 Gene3D G3DSA:1.10.10.10 9 71 5.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21775 1f8181a0b976cf7aef519226150b8a42 434 Pfam PF13280 WYL domain 233 428 1.8E-29 T 29-03-2018 IPR026881 WYL domain A616_RS21775 1f8181a0b976cf7aef519226150b8a42 434 Pfam PF08279 HTH domain 12 52 7.9E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS21775 1f8181a0b976cf7aef519226150b8a42 434 Gene3D G3DSA:1.10.10.10 85 158 6.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04650 81f215cae0a3197d24f60dad070a6bd3 301 Gene3D G3DSA:3.40.50.720 2 112 3.4E-10 T 29-03-2018 A616_RS04650 81f215cae0a3197d24f60dad070a6bd3 301 SUPERFAMILY SSF51735 19 131 6.19E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04650 81f215cae0a3197d24f60dad070a6bd3 301 SUPERFAMILY SSF55347 106 263 4.19E-16 T 29-03-2018 A616_RS04650 81f215cae0a3197d24f60dad070a6bd3 301 Gene3D G3DSA:3.30.360.10 113 297 4.0E-27 T 29-03-2018 A616_RS03540 df14494f3774ce6f187566fb35be07e8 399 Gene3D G3DSA:1.20.1090.10 192 399 1.3E-38 T 29-03-2018 A616_RS03540 df14494f3774ce6f187566fb35be07e8 399 SUPERFAMILY SSF56796 4 397 4.97E-100 T 29-03-2018 A616_RS03540 df14494f3774ce6f187566fb35be07e8 399 Gene3D G3DSA:3.40.50.1970 9 191 7.1E-51 T 29-03-2018 A616_RS03540 df14494f3774ce6f187566fb35be07e8 399 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 371 6.0E-102 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A616_RS03540 df14494f3774ce6f187566fb35be07e8 399 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 181 209 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 PIRSF PIRSF036497 1 336 8.3E-83 T 29-03-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 Gene3D G3DSA:3.30.360.10 173 314 4.6E-43 T 29-03-2018 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 Gene3D G3DSA:3.40.50.720 1 172 6.8E-27 T 29-03-2018 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 141 4.2E-10 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 198 220 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 Pfam PF00742 Homoserine dehydrogenase 152 330 8.1E-48 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 SUPERFAMILY SSF55347 152 314 1.24E-40 T 29-03-2018 A616_RS17775 fb2c1404f6ba79711d18817a1597d334 336 SUPERFAMILY SSF51735 1 173 5.55E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS17605 26dd20879983e390af74160be2c34216 311 Pfam PF14080 Domain of unknown function (DUF4261) 221 298 7.7E-21 T 29-03-2018 IPR025357 Domain of unknown function DUF4261 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Pfam PF00958 GMP synthase C terminal domain 420 511 1.8E-43 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 8 195 3.5E-80 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Pfam PF02540 NAD synthase 213 284 1.7E-6 T 29-03-2018 IPR022310 NAD/GMP synthase A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Gene3D G3DSA:3.30.300.10 388 512 8.4E-54 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 5 512 55.293 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Pfam PF00117 Glutamine amidotransferase class-I 9 190 7.7E-42 T 29-03-2018 IPR017926 Glutamine amidotransferase A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Gene3D G3DSA:3.40.50.880 3 223 2.9E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00097 Anthranilate synthase component II signature 52 61 9.7E-7 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00097 Anthranilate synthase component II signature 167 180 9.7E-7 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00097 Anthranilate synthase component II signature 79 90 9.7E-7 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 512 8.7E-156 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 SUPERFAMILY SSF54810 392 512 9.02E-51 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 SUPERFAMILY SSF52317 4 227 4.03E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 SUPERFAMILY SSF52402 187 405 9.26E-59 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 3.2E-6 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 8 22 3.2E-6 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 3.2E-6 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 8.1E-8 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 8.1E-8 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 8.1E-8 T 29-03-2018 A616_RS03175 9a172d66a8f85a477d8d4e01edc1df40 512 Gene3D G3DSA:3.40.50.620 224 380 6.2E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS21385 055a334cda42c40ca903fa5d35eb641d 512 Gene3D G3DSA:3.90.226.10 1 251 1.4E-61 T 29-03-2018 A616_RS21385 055a334cda42c40ca903fa5d35eb641d 512 Pfam PF01039 Carboxyl transferase domain 30 509 1.2E-154 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A616_RS21385 055a334cda42c40ca903fa5d35eb641d 512 SUPERFAMILY SSF52096 213 490 1.28E-82 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS21385 055a334cda42c40ca903fa5d35eb641d 512 SUPERFAMILY SSF52096 6 249 3.56E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS21385 055a334cda42c40ca903fa5d35eb641d 512 Gene3D G3DSA:3.90.226.10 252 508 2.5E-68 T 29-03-2018 A616_RS00830 167fa30e10f21709c171e3897c496141 111 Gene3D G3DSA:1.10.10.10 2 110 3.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00830 167fa30e10f21709c171e3897c496141 111 SUPERFAMILY SSF46785 5 100 3.54E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00830 167fa30e10f21709c171e3897c496141 111 Pfam PF03551 Transcriptional regulator PadR-like family 16 90 5.5E-24 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS17890 859d9d254ba68e2aab707efd1cdea267 400 Gene3D G3DSA:1.10.150.20 174 286 0.002 T 29-03-2018 A616_RS17890 859d9d254ba68e2aab707efd1cdea267 400 Gene3D G3DSA:1.10.150.20 287 369 0.0023 T 29-03-2018 A616_RS17890 859d9d254ba68e2aab707efd1cdea267 400 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 361 1.5E-27 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A616_RS17890 859d9d254ba68e2aab707efd1cdea267 400 Pfam PF01548 Transposase 5 163 3.3E-33 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A616_RS28925 0607a879a9a1e82c99bd1a1c3902d700 258 Pfam PF01061 ABC-2 type transporter 21 212 3.4E-8 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 Gene3D G3DSA:2.40.30.20 1 92 2.3E-30 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 Pfam PF00677 Lumazine binding domain 99 183 1.9E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 Pfam PF00677 Lumazine binding domain 3 86 1.2E-24 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 Gene3D G3DSA:2.40.30.20 101 205 1.3E-33 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 199 2.4E-74 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 PIRSF PIRSF000498 1 207 9.5E-79 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 SUPERFAMILY SSF63380 1 92 1.02E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A616_RS26540 ff06de11bbf40966c84e872827dbe265 218 SUPERFAMILY SSF63380 93 196 3.32E-33 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 Gene3D G3DSA:3.40.50.300 64 225 2.0E-28 T 29-03-2018 A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 SUPERFAMILY SSF50249 1 64 7.11E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 SUPERFAMILY SSF52540 66 290 3.24E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 Pfam PF03193 RsgA GTPase 62 225 6.0E-61 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 Gene3D G3DSA:2.40.50.140 1 63 1.7E-22 T 29-03-2018 A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 41 282 4.1E-84 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 Pfam PF16745 RsgA N-terminal domain 3 58 8.0E-24 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 Gene3D G3DSA:1.10.40.50 227 295 6.4E-21 T 29-03-2018 A616_RS20755 9cbd3212cd002269e6cd85e012825a98 296 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 290 38.206 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A616_RS21690 1b08cdd4e0f9c1963a5d4ae526f629aa 484 Pfam PF12704 MacB-like periplasmic core domain 21 314 1.9E-14 T 29-03-2018 IPR025857 MacB-like periplasmic core domain A616_RS21690 1b08cdd4e0f9c1963a5d4ae526f629aa 484 Pfam PF02687 FtsX-like permease family 368 475 7.4E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS12945 6d90f9adebb0a501b84c980a4f142cb4 276 Pfam PF03099 Biotin/lipoate A/B protein ligase family 51 187 1.1E-27 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A616_RS12945 6d90f9adebb0a501b84c980a4f142cb4 276 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 1 276 67.927 T 29-03-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A616_RS12945 6d90f9adebb0a501b84c980a4f142cb4 276 Gene3D G3DSA:3.30.930.10 1 276 9.8E-57 T 29-03-2018 A616_RS12945 6d90f9adebb0a501b84c980a4f142cb4 276 SUPERFAMILY SSF55681 1 275 1.24E-70 T 29-03-2018 A616_RS10910 2669a460f35fadcc409c7daff723067c 441 SUPERFAMILY SSF160631 34 166 1.14E-13 T 29-03-2018 A616_RS10910 2669a460f35fadcc409c7daff723067c 441 SMART SM00860 36 160 0.0011 T 29-03-2018 IPR018958 Knr4/Smi1-like domain A616_RS10910 2669a460f35fadcc409c7daff723067c 441 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 36 159 8.8E-9 T 29-03-2018 IPR018958 Knr4/Smi1-like domain A616_RS10910 2669a460f35fadcc409c7daff723067c 441 Gene3D G3DSA:3.40.1580.10 6 165 7.4E-17 T 29-03-2018 A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 Pfam PF00582 Universal stress protein family 149 287 1.3E-22 T 29-03-2018 IPR006016 UspA GO:0006950 A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 Pfam PF00582 Universal stress protein family 2 136 2.8E-21 T 29-03-2018 IPR006016 UspA GO:0006950 A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 PRINTS PR01438 Universal stress protein signature 148 166 4.2E-16 T 29-03-2018 IPR006015 Universal stress protein A A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 PRINTS PR01438 Universal stress protein signature 265 287 4.2E-16 T 29-03-2018 IPR006015 Universal stress protein A A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 PRINTS PR01438 Universal stress protein signature 247 259 4.2E-16 T 29-03-2018 IPR006015 Universal stress protein A A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 Gene3D G3DSA:3.40.50.620 1 139 8.2E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 SUPERFAMILY SSF52402 147 287 9.77E-29 T 29-03-2018 A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 Gene3D G3DSA:3.40.50.620 140 288 7.5E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS12325 f9acca5d91755597ae6cd6c3a402cf18 288 SUPERFAMILY SSF52402 1 137 1.26E-26 T 29-03-2018 A616_RS14090 e30b8e9e2b971fe0627d0bd188819488 265 Gene3D G3DSA:1.10.510.10 35 208 7.6E-20 T 29-03-2018 A616_RS14090 e30b8e9e2b971fe0627d0bd188819488 265 SUPERFAMILY SSF56112 11 239 6.13E-23 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS14090 e30b8e9e2b971fe0627d0bd188819488 265 Pfam PF01636 Phosphotransferase enzyme family 117 171 3.6E-11 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS11320 947e13e2eaf112324d3b4bdba6399d2e 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 2.6E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS11320 947e13e2eaf112324d3b4bdba6399d2e 336 Gene3D G3DSA:1.10.3720.10 4 323 1.0E-48 T 29-03-2018 A616_RS11320 947e13e2eaf112324d3b4bdba6399d2e 336 SUPERFAMILY SSF161098 91 161 1.0E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS11320 947e13e2eaf112324d3b4bdba6399d2e 336 SUPERFAMILY SSF161098 198 320 1.0E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 Gene3D G3DSA:3.50.30.30 109 210 6.3E-27 T 29-03-2018 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 SUPERFAMILY SSF52025 103 220 9.42E-20 T 29-03-2018 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 Gene3D G3DSA:3.40.630.10 21 108 0.19 T 29-03-2018 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 Gene3D G3DSA:3.40.630.10 211 419 1.2E-9 T 29-03-2018 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 Pfam PF04389 Peptidase family M28 232 384 5.2E-17 T 29-03-2018 IPR007484 Peptidase M28 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 Pfam PF02225 PA domain 121 204 6.1E-15 T 29-03-2018 IPR003137 PA domain A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 SUPERFAMILY SSF53187 24 87 3.04E-32 T 29-03-2018 A616_RS12955 8a517bd06197ea2f569d726247fa837b 445 SUPERFAMILY SSF53187 224 416 3.04E-32 T 29-03-2018 A616_RS19200 c4f1772fb368703589923f5f374166d3 177 SUPERFAMILY SSF51261 58 148 6.8E-13 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS19200 c4f1772fb368703589923f5f374166d3 177 Gene3D G3DSA:2.70.70.10 3 155 1.9E-18 T 29-03-2018 A616_RS19200 c4f1772fb368703589923f5f374166d3 177 Pfam PF01551 Peptidase family M23 56 148 3.4E-12 T 29-03-2018 IPR016047 Peptidase M23 A616_RS02250 af9617f29fec22e428923c9c7c2d5ec7 122 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 115 7.2E-38 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 A616_RS14565 db962c4406dd4ddd15e0d10935c83aa7 208 Pfam PF01810 LysE type translocator 17 206 2.3E-30 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS14565 db962c4406dd4ddd15e0d10935c83aa7 208 PIRSF PIRSF006324 1 208 1.5E-52 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 Gene3D G3DSA:1.10.10.60 9 82 3.4E-14 T 29-03-2018 A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.9E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.9E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 SUPERFAMILY SSF48498 121 193 1.54E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 SUPERFAMILY SSF46689 10 71 6.8E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 3.8E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS23175 307f5838e139a2e11ec16a49115b3352 210 Gene3D G3DSA:1.10.357.10 83 202 2.8E-5 T 29-03-2018 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 284 6.5E-115 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 SUPERFAMILY SSF51569 2 283 1.45E-100 T 29-03-2018 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 283 3.9E-98 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 Gene3D G3DSA:3.20.20.70 1 284 1.2E-106 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 1.4E-98 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS30100 81b7d0e3b6897854103c1a3adb5d3988 284 PIRSF PIRSF001359 1 284 1.4E-109 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A616_RS09095 cd1de10d4a1e4ddc20340b4c62c53dbf 486 Pfam PF00171 Aldehyde dehydrogenase family 17 475 2.8E-159 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS09095 cd1de10d4a1e4ddc20340b4c62c53dbf 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS09095 cd1de10d4a1e4ddc20340b4c62c53dbf 486 Gene3D G3DSA:3.40.309.10 272 460 1.0E-68 T 29-03-2018 A616_RS09095 cd1de10d4a1e4ddc20340b4c62c53dbf 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A616_RS09095 cd1de10d4a1e4ddc20340b4c62c53dbf 486 Gene3D G3DSA:3.40.605.10 3 271 1.0E-81 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS09095 cd1de10d4a1e4ddc20340b4c62c53dbf 486 SUPERFAMILY SSF53720 5 477 1.23E-153 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 Gene3D G3DSA:3.30.300.20 58 135 3.3E-21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 Pfam PF14804 Jag N-terminus 7 55 1.8E-20 T 29-03-2018 IPR032782 Jag, N-terminal A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 SMART SM00393 126 205 6.9E-21 T 29-03-2018 IPR001374 R3H domain GO:0003676 A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 Gene3D G3DSA:3.30.30.80 3 54 2.7E-20 T 29-03-2018 A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 Pfam PF01424 R3H domain 144 203 2.4E-16 T 29-03-2018 IPR001374 R3H domain GO:0003676 A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 SMART SM01245 5 57 4.0E-22 T 29-03-2018 IPR032782 Jag, N-terminal A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 Pfam PF13083 KH domain 65 132 2.8E-17 T 29-03-2018 A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 Gene3D G3DSA:3.30.1370.50 137 209 2.6E-20 T 29-03-2018 IPR001374 R3H domain GO:0003676 A616_RS32290 023ee6f90144137d1c6fdc108a581f92 209 SUPERFAMILY SSF82708 147 205 6.28E-9 T 29-03-2018 IPR001374 R3H domain GO:0003676 A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 347 364 19.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 227 247 0.5 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 203 223 0.0054 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 156 170 9.7 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 275 295 0.41 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 299 320 0.079 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 323 343 0.042 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 179 193 8.8 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 371 388 0.24 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Pfam PF02493 MORN repeat 132 152 0.4 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SUPERFAMILY SSF82185 295 405 3.14E-20 T 29-03-2018 A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SUPERFAMILY SSF82185 177 297 1.37E-26 T 29-03-2018 A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 154 175 16.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 369 390 8.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 297 318 0.6 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 177 198 20.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 273 294 55.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 130 151 57.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 345 366 16.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 225 246 13.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 321 342 32.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 SMART SM00698 201 222 12.0 T 29-03-2018 IPR003409 MORN motif A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Gene3D G3DSA:2.20.110.10 116 192 3.7E-10 T 29-03-2018 A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Gene3D G3DSA:2.20.110.10 193 255 2.3E-13 T 29-03-2018 A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Gene3D G3DSA:2.20.110.10 327 443 4.9E-11 T 29-03-2018 A616_RS23290 a7addd5e4a9fa44387e20b0946cc1fb5 557 Gene3D G3DSA:2.20.110.10 256 326 9.0E-13 T 29-03-2018 A616_RS24285 e1bb65c941a9b4f11b774ff87f842bbf 378 Pfam PF04892 VanZ like family 48 196 1.4E-23 T 29-03-2018 IPR006976 VanZ-like A616_RS24285 e1bb65c941a9b4f11b774ff87f842bbf 378 Pfam PF06271 RDD family 225 371 1.4E-10 T 29-03-2018 IPR010432 RDD A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 SUPERFAMILY SSF141868 554 799 1.7E-92 T 29-03-2018 IPR001633 EAL domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 SMART SM00267 367 538 2.5E-69 T 29-03-2018 IPR000160 GGDEF domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Gene3D G3DSA:3.20.20.450 542 805 9.4E-106 T 29-03-2018 IPR001633 EAL domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 373 3.7E-11 T 29-03-2018 IPR000014 PAS domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Gene3D G3DSA:3.30.450.20 241 374 2.8E-15 T 29-03-2018 A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Pfam PF03707 Bacterial signalling protein N terminal repeat 54 111 3.2E-16 T 29-03-2018 IPR005330 MHYT domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Pfam PF03707 Bacterial signalling protein N terminal repeat 117 166 1.3E-13 T 29-03-2018 IPR005330 MHYT domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 SUPERFAMILY SSF55785 252 365 7.04E-12 T 29-03-2018 IPR000014 PAS domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 376 535 3.6E-44 T 29-03-2018 IPR000160 GGDEF domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 SUPERFAMILY SSF55073 383 538 7.85E-49 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Pfam PF00563 EAL domain 554 788 1.0E-74 T 29-03-2018 IPR001633 EAL domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Pfam PF00990 Diguanylate cyclase, GGDEF domain 378 533 2.0E-50 T 29-03-2018 IPR000160 GGDEF domain A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 Gene3D G3DSA:3.30.70.270 375 541 5.4E-60 T 29-03-2018 A616_RS12115 04eb5324c0dcc6e0b7caaa469dc86ad0 805 SMART SM00052 548 793 1.7E-131 T 29-03-2018 IPR001633 EAL domain A616_RS26945 24e7fc4bffc29203beca25eb13731a40 502 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 29 491 2.2E-140 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS26945 24e7fc4bffc29203beca25eb13731a40 502 PIRSF PIRSF005690 14 502 3.2E-138 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS13325 b55812bd207bb0b261ab913739c758ee 208 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 204 5.7E-59 T 29-03-2018 IPR014196 Stage II sporulation protein M A616_RS13325 b55812bd207bb0b261ab913739c758ee 208 Pfam PF01944 Stage II sporulation protein M 24 200 5.3E-26 T 29-03-2018 IPR002798 Stage II sporulation protein M-like A616_RS13325 b55812bd207bb0b261ab913739c758ee 208 PIRSF PIRSF038973 1 208 3.9E-63 T 29-03-2018 IPR014196 Stage II sporulation protein M A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 SMART SM00065 304 429 0.26 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 SMART SM00065 450 589 5.5E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 588 745 2.2E-42 T 29-03-2018 IPR000160 GGDEF domain A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 SMART SM00267 581 746 4.9E-52 T 29-03-2018 IPR000160 GGDEF domain A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 Gene3D G3DSA:3.30.450.40 148 282 0.013 T 29-03-2018 IPR029016 GAF domain-like A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 SUPERFAMILY SSF55073 597 745 1.8E-43 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 SUPERFAMILY SSF55781 432 587 2.62E-21 T 29-03-2018 IPR029016 GAF domain-like A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 Gene3D G3DSA:3.30.450.40 440 589 5.5E-24 T 29-03-2018 IPR029016 GAF domain-like A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 Gene3D G3DSA:3.30.70.270 590 746 1.1E-49 T 29-03-2018 A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 Pfam PF00990 Diguanylate cyclase, GGDEF domain 593 742 3.0E-41 T 29-03-2018 IPR000160 GGDEF domain A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 Pfam PF13185 GAF domain 449 579 5.1E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 SUPERFAMILY SSF55781 287 446 6.54E-16 T 29-03-2018 IPR029016 GAF domain-like A616_RS22935 7cf5f79f684aebab77d8bcac4c96f77d 746 Gene3D G3DSA:3.30.450.40 283 439 4.3E-15 T 29-03-2018 IPR029016 GAF domain-like A616_RS05990 26ded0cbecbf9d723ff700a232a1ab04 303 Gene3D G3DSA:3.40.50.720 1 298 2.5E-48 T 29-03-2018 A616_RS05990 26ded0cbecbf9d723ff700a232a1ab04 303 SUPERFAMILY SSF51735 1 269 3.92E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS05990 26ded0cbecbf9d723ff700a232a1ab04 303 Pfam PF13460 NAD(P)H-binding 7 203 5.7E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS02045 1287a8015a3576f9f09f5999e870b772 339 Pfam PF01032 FecCD transport family 18 336 3.1E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS02045 1287a8015a3576f9f09f5999e870b772 339 SUPERFAMILY SSF81345 6 336 8.24E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS02045 1287a8015a3576f9f09f5999e870b772 339 Gene3D G3DSA:1.10.3470.10 3 339 4.9E-66 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS22315 e86020e98e03ff1069c459d93b1dd02f 407 Gene3D G3DSA:1.20.1250.20 213 406 5.5E-17 T 29-03-2018 A616_RS22315 e86020e98e03ff1069c459d93b1dd02f 407 SUPERFAMILY SSF103473 18 403 1.23E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS22315 e86020e98e03ff1069c459d93b1dd02f 407 Gene3D G3DSA:1.20.1250.20 6 209 5.9E-27 T 29-03-2018 A616_RS22315 e86020e98e03ff1069c459d93b1dd02f 407 Pfam PF07690 Major Facilitator Superfamily 24 248 3.9E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS22315 e86020e98e03ff1069c459d93b1dd02f 407 Pfam PF07690 Major Facilitator Superfamily 254 400 5.8E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS26215 72058c1510450e075f6f46b53c932a2a 192 Gene3D G3DSA:3.40.390.10 33 192 7.7E-12 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A616_RS26215 72058c1510450e075f6f46b53c932a2a 192 SUPERFAMILY SSF55486 51 192 1.1E-10 T 29-03-2018 A616_RS27965 97bd22a89a4fd2a94fbcd6375f53432a 120 Pfam PF00072 Response regulator receiver domain 4 115 4.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27965 97bd22a89a4fd2a94fbcd6375f53432a 120 SMART SM00448 2 115 3.9E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27965 97bd22a89a4fd2a94fbcd6375f53432a 120 Gene3D G3DSA:3.40.50.2300 1 120 2.7E-35 T 29-03-2018 A616_RS27965 97bd22a89a4fd2a94fbcd6375f53432a 120 SUPERFAMILY SSF52172 1 119 1.15E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 Gene3D G3DSA:3.40.50.1390 1 120 7.1E-44 T 29-03-2018 A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 Gene3D G3DSA:1.20.5.40 121 149 8.8E-10 T 29-03-2018 A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 Pfam PF13408 Recombinase zinc beta ribbon domain 284 346 1.1E-14 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 SMART SM00857 3 151 3.4E-60 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 Pfam PF07508 Recombinase 173 271 1.2E-25 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 SUPERFAMILY SSF53041 1 147 2.22E-39 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS23045 9edbd765e858a1c871a34735ff1eda2f 483 Pfam PF00239 Resolvase, N terminal domain 4 148 1.1E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 SUPERFAMILY SSF53850 90 290 3.82E-42 T 29-03-2018 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 Gene3D G3DSA:3.40.190.10 176 262 1.3E-21 T 29-03-2018 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 Pfam PF03466 LysR substrate binding domain 89 286 1.6E-45 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 Gene3D G3DSA:1.10.10.10 1 83 3.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 Gene3D G3DSA:3.40.190.10 87 175 3.2E-22 T 29-03-2018 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.3E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS20590 850c07f0de880dd8d9363fb187e5b578 292 SUPERFAMILY SSF46785 3 111 1.06E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Pfam PF04509 CheC-like family 42 78 1.1E-15 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Pfam PF04509 CheC-like family 140 173 2.0E-12 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 SUPERFAMILY SSF101801 370 450 1.96E-23 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Gene3D G3DSA:3.40.1550.10 2 86 5.1E-20 T 29-03-2018 IPR028976 CheC-like domain A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Gene3D G3DSA:3.40.1550.10 213 253 0.3 T 29-03-2018 IPR028976 CheC-like domain A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Gene3D G3DSA:3.40.1550.10 87 212 9.4E-36 T 29-03-2018 IPR028976 CheC-like domain A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Gene3D G3DSA:2.30.330.10 365 453 1.1E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 373 443 1.5E-24 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 370 445 7.0E-30 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 SUPERFAMILY SSF103039 37 231 9.59E-51 T 29-03-2018 IPR028976 CheC-like domain A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 PRINTS PR00956 Flagellar motor switch protein FliN signature 373 389 7.3E-26 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 PRINTS PR00956 Flagellar motor switch protein FliN signature 419 434 7.3E-26 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 PRINTS PR00956 Flagellar motor switch protein FliN signature 390 406 7.3E-26 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A616_RS19980 c371f00b0e29f5bd4e4536c2eccf48b7 453 PRINTS PR00956 Flagellar motor switch protein FliN signature 406 419 7.3E-26 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A616_RS11570 12e5dce8846324ca84d06f1f74d72888 279 Gene3D G3DSA:3.20.20.150 1 272 4.9E-49 T 29-03-2018 A616_RS11570 12e5dce8846324ca84d06f1f74d72888 279 Pfam PF01261 Xylose isomerase-like TIM barrel 22 233 5.1E-29 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS11570 12e5dce8846324ca84d06f1f74d72888 279 SUPERFAMILY SSF51658 1 258 2.63E-47 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS31315 dd352d6a53bc9b8121c0d37ff7b6e5ea 311 Gene3D G3DSA:3.40.50.1980 149 311 5.7E-31 T 29-03-2018 A616_RS31315 dd352d6a53bc9b8121c0d37ff7b6e5ea 311 Pfam PF01497 Periplasmic binding protein 58 288 4.1E-32 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS31315 dd352d6a53bc9b8121c0d37ff7b6e5ea 311 SUPERFAMILY SSF53807 45 306 2.55E-54 T 29-03-2018 A616_RS31315 dd352d6a53bc9b8121c0d37ff7b6e5ea 311 Gene3D G3DSA:3.40.50.1980 37 148 1.5E-20 T 29-03-2018 A616_RS31735 9dd39aa6732864e26baafb13310dab8f 422 Pfam PF01381 Helix-turn-helix 12 65 3.9E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS31735 9dd39aa6732864e26baafb13310dab8f 422 Gene3D G3DSA:1.10.260.40 1 128 4.5E-14 T 29-03-2018 A616_RS31735 9dd39aa6732864e26baafb13310dab8f 422 SUPERFAMILY SSF48452 193 319 1.99E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31735 9dd39aa6732864e26baafb13310dab8f 422 Gene3D G3DSA:1.25.40.10 152 404 1.5E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31735 9dd39aa6732864e26baafb13310dab8f 422 SMART SM00530 11 67 9.4E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS31735 9dd39aa6732864e26baafb13310dab8f 422 SUPERFAMILY SSF47413 2 66 1.35E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS20140 231d42c31caa1837df5b0c61c2dfc84c 102 SUPERFAMILY SSF141066 3 97 2.22E-20 T 29-03-2018 IPR018990 Proteinase inhibitor I42, chagasin A616_RS20140 231d42c31caa1837df5b0c61c2dfc84c 102 Pfam PF09394 Chagasin family peptidase inhibitor I42 11 91 1.4E-20 T 29-03-2018 IPR018990 Proteinase inhibitor I42, chagasin A616_RS09855 b03afab9287571bb77109987f9b1f52e 173 Gene3D G3DSA:2.70.70.10 20 171 9.3E-36 T 29-03-2018 A616_RS09855 b03afab9287571bb77109987f9b1f52e 173 SUPERFAMILY SSF51261 29 168 1.1E-42 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS09855 b03afab9287571bb77109987f9b1f52e 173 Pfam PF01551 Peptidase family M23 70 164 7.0E-27 T 29-03-2018 IPR016047 Peptidase M23 A616_RS25410 6b88bb15deae85adb1b947f3ac4d9e68 337 PIRSF PIRSF000267 1 337 8.6E-113 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A616_RS25410 6b88bb15deae85adb1b947f3ac4d9e68 337 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 225 3.5E-82 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A616_RS25410 6b88bb15deae85adb1b947f3ac4d9e68 337 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 325 3.1E-103 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A616_RS20005 fe5bd5aaacfd57e2f97e2b02c182baf4 131 Pfam PF12611 Putative flagellar 108 130 1.5E-11 T 29-03-2018 IPR013367 Flagellar, putative A616_RS20005 fe5bd5aaacfd57e2f97e2b02c182baf4 131 TIGRFAM TIGR02530 flg_new: flagellar operon protein 33 130 2.4E-29 T 29-03-2018 IPR013367 Flagellar, putative A616_RS23370 907c0359d5eddecf01ef466b0b3d9c4c 319 Gene3D G3DSA:3.40.50.20 1 111 1.5E-15 T 29-03-2018 A616_RS23370 907c0359d5eddecf01ef466b0b3d9c4c 319 Pfam PF02655 ATP-grasp domain 109 271 2.0E-17 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 A616_RS23370 907c0359d5eddecf01ef466b0b3d9c4c 319 Gene3D G3DSA:3.30.470.20 189 308 7.7E-11 T 29-03-2018 A616_RS23370 907c0359d5eddecf01ef466b0b3d9c4c 319 SUPERFAMILY SSF56059 106 293 2.09E-27 T 29-03-2018 A616_RS23370 907c0359d5eddecf01ef466b0b3d9c4c 319 Gene3D G3DSA:3.30.1490.20 112 188 2.2E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 Gene3D G3DSA:3.40.50.620 10 179 4.4E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 Pfam PF01687 Riboflavin kinase 184 306 1.8E-37 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 SMART SM00904 183 309 3.4E-57 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 308 5.8E-89 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 SUPERFAMILY SSF82114 174 309 2.83E-44 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 PIRSF PIRSF004491 3 313 5.0E-106 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 Pfam PF06574 FAD synthetase 16 166 2.4E-46 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 Gene3D G3DSA:2.40.30.30 180 312 2.7E-42 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 A616_RS19775 2dd0a77f673e90d68e262c46dbef85de 313 SUPERFAMILY SSF52374 18 184 2.95E-30 T 29-03-2018 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 Pfam PF08281 Sigma-70, region 4 110 162 5.7E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 37 68 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 Pfam PF04542 Sigma-70 region 2 16 79 2.6E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 Gene3D G3DSA:1.10.10.10 89 173 3.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11380 34923c87db789b4d63fa371e536559ab 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 165 2.9E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 Gene3D G3DSA:1.10.1740.10 2 84 1.1E-20 T 29-03-2018 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 SUPERFAMILY SSF88659 107 167 4.49E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11380 34923c87db789b4d63fa371e536559ab 182 SUPERFAMILY SSF88946 8 91 5.1E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18840 136c82215ab582348618a2cefcf28fbf 226 Pfam PF00149 Calcineurin-like phosphoesterase 3 192 3.8E-19 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS18840 136c82215ab582348618a2cefcf28fbf 226 SUPERFAMILY SSF56300 3 218 1.14E-43 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS18840 136c82215ab582348618a2cefcf28fbf 226 Gene3D G3DSA:3.60.21.10 1 226 7.1E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS30475 6a0ecad1560d901374c8dfd20a572e06 442 Pfam PF13416 Bacterial extracellular solute-binding protein 70 377 6.5E-54 T 29-03-2018 A616_RS30475 6a0ecad1560d901374c8dfd20a572e06 442 Gene3D G3DSA:3.40.190.10 52 240 3.5E-40 T 29-03-2018 A616_RS30475 6a0ecad1560d901374c8dfd20a572e06 442 Gene3D G3DSA:3.40.190.10 247 399 5.1E-15 T 29-03-2018 A616_RS30475 6a0ecad1560d901374c8dfd20a572e06 442 SUPERFAMILY SSF53850 50 440 1.56E-84 T 29-03-2018 A616_RS22275 023a73e9e4fc3baa67cdbd12612a7b14 157 Gene3D G3DSA:2.30.30.40 99 145 1.7E-15 T 29-03-2018 A616_RS22275 023a73e9e4fc3baa67cdbd12612a7b14 157 Gene3D G3DSA:2.40.50.180 35 98 2.9E-20 T 29-03-2018 A616_RS22275 023a73e9e4fc3baa67cdbd12612a7b14 157 SUPERFAMILY SSF50341 11 153 5.89E-39 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS22275 023a73e9e4fc3baa67cdbd12612a7b14 157 Pfam PF01584 CheW-like domain 20 152 1.1E-32 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS22275 023a73e9e4fc3baa67cdbd12612a7b14 157 SMART SM00260 14 151 4.8E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 417 42.916 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 SUPERFAMILY SSF51338 377 419 2.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 SUPERFAMILY SSF51338 35 80 2.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 Gene3D G3DSA:3.20.20.140 95 356 4.0E-42 T 29-03-2018 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 Gene3D G3DSA:2.30.40.10 357 420 1.1E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 Gene3D G3DSA:2.30.40.10 4 94 1.3E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 Pfam PF01979 Amidohydrolase family 76 415 2.1E-20 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 416 1.6E-149 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS23305 035c1e0abfc424e1dcf9a3f69469c4e2 424 SUPERFAMILY SSF51556 79 378 2.14E-87 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 SUPERFAMILY SSF53927 4 145 8.7E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 SUPERFAMILY SSF53597 146 357 2.32E-59 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 100 8.8E-22 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 354 1.3E-63 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 Gene3D G3DSA:3.40.140.10 1 125 2.6E-35 T 29-03-2018 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 353 2.3E-119 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 Gene3D G3DSA:3.40.430.10 126 367 2.9E-77 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 Pfam PF01872 RibD C-terminal domain 148 354 4.9E-51 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A616_RS26545 c538270310af6975fbdb6f6c30bbd44b 368 PIRSF PIRSF006769 1 362 4.0E-136 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 Gene3D G3DSA:2.40.50.100 239 303 1.7E-5 T 29-03-2018 A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 Gene3D G3DSA:3.40.50.300 1 238 3.9E-72 T 29-03-2018 A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 SMART SM00382 28 211 1.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 Pfam PF08402 TOBE domain 283 355 1.5E-5 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 SUPERFAMILY SSF50331 236 331 6.56E-12 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 SUPERFAMILY SSF52540 4 242 1.15E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24970 8569e3b056e5b0b348f1e0cba5d8eeac 358 Pfam PF00005 ABC transporter 20 161 1.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS04560 6ac26cebfcd76cdc0c807a81ec723126 352 Pfam PF00487 Fatty acid desaturase 51 290 2.9E-39 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Pfam PF00005 ABC transporter 19 195 9.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Pfam PF00005 ABC transporter 348 476 3.1E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 ProSitePatterns PS00211 ABC transporters family signature. 448 462 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Pfam PF12848 ABC transporter 234 318 9.9E-27 T 29-03-2018 IPR032781 ABC-transporter extension domain A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Pfam PF16326 ABC transporter C-terminal domain 577 643 1.4E-11 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Gene3D G3DSA:3.40.50.300 4 294 2.8E-54 T 29-03-2018 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 SMART SM00382 28 242 1.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 SMART SM00382 355 521 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Gene3D G3DSA:1.20.58.410 576 644 0.0011 T 29-03-2018 A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 SUPERFAMILY SSF52540 4 248 1.4E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 SUPERFAMILY SSF52540 312 534 1.85E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02980 ce8e03e4dda06875f6b0780b6cadde5a 644 Gene3D G3DSA:3.40.50.300 295 557 2.1E-52 T 29-03-2018 A616_RS22850 3a63fd41ac06ad6f3810a02030cec2e8 497 Gene3D G3DSA:3.20.20.70 75 409 8.3E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS22850 3a63fd41ac06ad6f3810a02030cec2e8 497 PIRSF PIRSF012702 1 494 2.7E-159 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC A616_RS22850 3a63fd41ac06ad6f3810a02030cec2e8 497 Pfam PF07364 Metallopeptidase family M81 2 289 1.0E-92 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal A616_RS22850 3a63fd41ac06ad6f3810a02030cec2e8 497 Pfam PF07171 MlrC C-terminus 299 475 1.3E-58 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal A616_RS21770 ee5003ffcacb3d81ed34ebd5744c3716 478 Pfam PF01139 tRNA-splicing ligase RtcB 52 477 1.5E-109 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A616_RS21770 ee5003ffcacb3d81ed34ebd5744c3716 478 SUPERFAMILY SSF103365 32 477 1.44E-113 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A616_RS12885 9953d958067e819fadfde7741384b991 319 Gene3D G3DSA:3.40.190.10 170 265 5.7E-6 T 29-03-2018 A616_RS12885 9953d958067e819fadfde7741384b991 319 Gene3D G3DSA:1.10.10.10 8 64 1.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12885 9953d958067e819fadfde7741384b991 319 Pfam PF12727 PBP superfamily domain 101 291 2.8E-58 T 29-03-2018 IPR024370 PBP domain A616_RS12885 9953d958067e819fadfde7741384b991 319 Pfam PF12728 Helix-turn-helix domain 7 54 2.4E-16 T 29-03-2018 A616_RS12885 9953d958067e819fadfde7741384b991 319 SUPERFAMILY SSF53850 106 306 1.96E-16 T 29-03-2018 A616_RS12885 9953d958067e819fadfde7741384b991 319 SUPERFAMILY SSF46955 7 52 2.56E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS12885 9953d958067e819fadfde7741384b991 319 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 2.8E-18 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A616_RS23355 9a5a7210be22e433b9c2dae6a2bf85b0 137 SUPERFAMILY SSF54593 6 135 3.22E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS23355 9a5a7210be22e433b9c2dae6a2bf85b0 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 122 5.2E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS23355 9a5a7210be22e433b9c2dae6a2bf85b0 137 Gene3D G3DSA:3.10.180.10 1 125 1.5E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 SUPERFAMILY SSF46934 3 54 2.15E-19 T 29-03-2018 IPR009060 UBA-like GO:0005515 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 SUPERFAMILY SSF54713 55 144 4.71E-22 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 Hamap MF_00050 Elongation factor Ts [tsf]. 1 292 80.601 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 Gene3D G3DSA:3.30.479.20 57 156 3.1E-26 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 Gene3D G3DSA:3.30.479.20 157 291 3.5E-49 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 2.8E-107 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 Pfam PF00889 Elongation factor TS 70 275 3.2E-71 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 SUPERFAMILY SSF54713 152 294 1.16E-50 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 Gene3D G3DSA:1.10.8.10 1 55 1.7E-24 T 29-03-2018 A616_RS19870 e4634aa9d734a227c56ce29371ec7cac 295 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A616_RS21655 75e87a8e5567fe1fc8b873ad9a2d40bc 182 SUPERFAMILY SSF55729 2 176 5.11E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS21655 75e87a8e5567fe1fc8b873ad9a2d40bc 182 Pfam PF13302 Acetyltransferase (GNAT) domain 8 152 5.5E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS21655 75e87a8e5567fe1fc8b873ad9a2d40bc 182 Gene3D G3DSA:3.40.630.30 1 182 1.5E-28 T 29-03-2018 A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.454 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 2.0E-88 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 Gene3D G3DSA:3.40.1360.10 77 170 9.9E-40 T 29-03-2018 A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 Pfam PF02132 RecR protein 39 78 3.2E-17 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 Pfam PF13662 Toprim domain 80 171 9.9E-26 T 29-03-2018 IPR006171 TOPRIM domain A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 Gene3D G3DSA:1.10.150.20 6 65 0.29 T 29-03-2018 A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 SUPERFAMILY SSF111304 1 198 5.36E-79 T 29-03-2018 IPR023627 Recombination protein RecR A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 SMART SM00493 80 165 1.2E-17 T 29-03-2018 IPR006171 TOPRIM domain A616_RS00520 9a26a451ccde8ede5c58e731bbe5ef0d 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A616_RS18760 66fb97273b3f4bc5325866fd3be9e9e3 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 31 104 7.4E-12 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A616_RS18760 66fb97273b3f4bc5325866fd3be9e9e3 109 Gene3D G3DSA:1.10.287.1080 1 109 2.6E-18 T 29-03-2018 A616_RS18760 66fb97273b3f4bc5325866fd3be9e9e3 109 SUPERFAMILY SSF101386 1 104 1.85E-25 T 29-03-2018 A616_RS18760 66fb97273b3f4bc5325866fd3be9e9e3 109 PIRSF PIRSF036521 1 107 5.5E-51 T 29-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related A616_RS22485 bf79381f8871e31d427fac409ee959bd 274 SUPERFAMILY SSF56281 14 229 8.4E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22485 bf79381f8871e31d427fac409ee959bd 274 Pfam PF00753 Metallo-beta-lactamase superfamily 14 182 4.9E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22485 bf79381f8871e31d427fac409ee959bd 274 SMART SM00849 14 195 6.9E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22485 bf79381f8871e31d427fac409ee959bd 274 Gene3D G3DSA:3.60.15.10 6 216 7.4E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 Gene3D G3DSA:3.50.50.60 6 154 2.5E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 Gene3D G3DSA:3.40.50.720 155 329 6.3E-23 T 29-03-2018 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 3.0E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 3.0E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 206 222 3.0E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 3.0E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 69 79 3.0E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 3.0E-26 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 Hamap MF_01685 Ferredoxin--NADP reductase. 10 331 44.188 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 SUPERFAMILY SSF51905 8 315 1.69E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.1E-19 T 29-03-2018 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 1.1E-19 T 29-03-2018 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.1E-19 T 29-03-2018 A616_RS26275 d09049909c1b68f0c1677a05c7760597 336 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 297 6.2E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10520 da0ed608390e0d2ba394dcc3401ad032 264 Pfam PF13614 AAA domain 5 159 8.7E-25 T 29-03-2018 IPR025669 AAA domain A616_RS10520 da0ed608390e0d2ba394dcc3401ad032 264 PIRSF PIRSF003092 2 264 3.3E-92 T 29-03-2018 IPR025501 ATP binding protein MinD A616_RS10520 da0ed608390e0d2ba394dcc3401ad032 264 Gene3D G3DSA:3.40.50.300 4 249 1.1E-57 T 29-03-2018 A616_RS10520 da0ed608390e0d2ba394dcc3401ad032 264 SUPERFAMILY SSF52540 5 250 1.86E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10520 da0ed608390e0d2ba394dcc3401ad032 264 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 5 261 2.0E-123 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 Gene3D G3DSA:3.40.640.10 165 286 5.6E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 7 391 45.925 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 Gene3D G3DSA:3.90.1150.10 3 164 6.0E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 PIRSF PIRSF000521 166 393 3.2E-37 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 PIRSF PIRSF000521 3 157 5.0E-10 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 SUPERFAMILY SSF53383 5 390 1.51E-127 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 Gene3D G3DSA:3.90.1150.10 287 393 1.3E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 Pfam PF00202 Aminotransferase class-III 16 390 3.4E-120 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS29360 98f855a6851ff7ac786894b0ce4448e0 393 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 10 390 8.1E-150 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 SUPERFAMILY SSF51556 96 157 1.22E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 SUPERFAMILY SSF51556 233 533 1.22E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 Gene3D G3DSA:2.30.40.10 31 200 5.0E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 Pfam PF07969 Amidohydrolase family 85 572 3.9E-92 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 SUPERFAMILY SSF51338 532 577 1.3E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 SUPERFAMILY SSF51338 32 97 1.3E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18410 b984cc9cf3f73e84165f60bcdf1967e3 579 Gene3D G3DSA:3.20.20.140 217 530 1.2E-51 T 29-03-2018 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 Pfam PF00171 Aldehyde dehydrogenase family 31 497 3.7E-186 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 297 308 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 SUPERFAMILY SSF53720 21 500 3.53E-179 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 Gene3D G3DSA:3.40.605.10 12 285 5.3E-111 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 269 276 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 Gene3D G3DSA:3.40.309.10 286 483 3.3E-77 T 29-03-2018 A616_RS15580 6ab8d9d49d49aeeddbcdd0b23c09d5c3 502 PIRSF PIRSF036492 50 502 4.7E-85 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A616_RS04025 82786af312b0a14ad933a033c6044373 478 Pfam PF02934 GatB/GatE catalytic domain 6 289 3.3E-116 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A616_RS04025 82786af312b0a14ad933a033c6044373 478 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 476 2.9E-186 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A616_RS04025 82786af312b0a14ad933a033c6044373 478 Gene3D G3DSA:1.10.10.410 415 476 3.7E-22 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A616_RS04025 82786af312b0a14ad933a033c6044373 478 SUPERFAMILY SSF55931 5 296 5.76E-126 T 29-03-2018 A616_RS04025 82786af312b0a14ad933a033c6044373 478 SUPERFAMILY SSF89095 297 403 4.36E-35 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A616_RS04025 82786af312b0a14ad933a033c6044373 478 Pfam PF02637 GatB domain 328 475 1.5E-55 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A616_RS04025 82786af312b0a14ad933a033c6044373 478 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 3 476 40.407 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 A616_RS04025 82786af312b0a14ad933a033c6044373 478 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A616_RS04025 82786af312b0a14ad933a033c6044373 478 SMART SM00845 328 475 2.8E-77 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A616_RS09925 368dd03c3cf171b885bc621453103d80 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 1.4E-27 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS09925 368dd03c3cf171b885bc621453103d80 329 Gene3D G3DSA:3.40.50.720 3 137 1.2E-41 T 29-03-2018 A616_RS09925 368dd03c3cf171b885bc621453103d80 329 SUPERFAMILY SSF55347 127 299 1.03E-26 T 29-03-2018 A616_RS09925 368dd03c3cf171b885bc621453103d80 329 SUPERFAMILY SSF51735 4 148 2.08E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09925 368dd03c3cf171b885bc621453103d80 329 Gene3D G3DSA:3.30.360.10 138 329 1.1E-40 T 29-03-2018 A616_RS09925 368dd03c3cf171b885bc621453103d80 329 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 197 6.0E-8 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS00735 20bcca448f3fe405b2f29f7a641246b1 711 Pfam PF09925 Predicted membrane protein (DUF2157) 10 114 5.1E-15 T 29-03-2018 IPR018677 Domain of unknown function DUF2157 A616_RS00735 20bcca448f3fe405b2f29f7a641246b1 711 Pfam PF14345 GDYXXLXY protein 563 708 5.4E-35 T 29-03-2018 IPR025833 GDYXXLXY protein A616_RS32315 551408d0f2897d05bb87b87bf83086a8 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 2 42 4.0E-12 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32315 551408d0f2897d05bb87b87bf83086a8 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 14.519 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32315 551408d0f2897d05bb87b87bf83086a8 44 Pfam PF00468 Ribosomal protein L34 1 44 1.5E-21 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS32315 551408d0f2897d05bb87b87bf83086a8 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 5.8E-18 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS00405 730545952226c5d0baeee584d18c9fac 401 Gene3D G3DSA:1.20.1250.20 194 396 5.5E-21 T 29-03-2018 A616_RS00405 730545952226c5d0baeee584d18c9fac 401 Gene3D G3DSA:1.20.1250.20 2 193 3.1E-23 T 29-03-2018 A616_RS00405 730545952226c5d0baeee584d18c9fac 401 Pfam PF07690 Major Facilitator Superfamily 11 346 2.5E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS00405 730545952226c5d0baeee584d18c9fac 401 SUPERFAMILY SSF103473 6 388 5.49E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS31770 7e2a2239c1a72c2a80f689d60d600f29 270 Gene3D G3DSA:1.10.3720.10 1 258 4.3E-44 T 29-03-2018 A616_RS31770 7e2a2239c1a72c2a80f689d60d600f29 270 SUPERFAMILY SSF161098 3 263 4.58E-71 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31770 7e2a2239c1a72c2a80f689d60d600f29 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 260 5.3E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS21885 7f4347017dab5bc68b059341c543e9cb 103 SMART SM00834 1 41 1.1E-7 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A616_RS21885 7f4347017dab5bc68b059341c543e9cb 103 Pfam PF09723 Zinc ribbon domain 1 39 3.3E-10 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A616_RS21885 7f4347017dab5bc68b059341c543e9cb 103 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 6.2E-13 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain A616_RS20535 e8978c9fb3ebecce4c458efdb76f887e 208 Pfam PF13559 Domain of unknown function (DUF4129) 132 190 4.7E-7 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 A616_RS28865 315d829b712082ae987855bd9ef9f560 341 Gene3D G3DSA:2.40.37.10 206 341 9.1E-6 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS28865 315d829b712082ae987855bd9ef9f560 341 SUPERFAMILY SSF51419 9 190 1.8E-7 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 194 8.5E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 350 2.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 Gene3D G3DSA:1.10.287.130 120 191 3.3E-18 T 29-03-2018 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 SUPERFAMILY SSF47384 113 194 1.0E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 Gene3D G3DSA:3.30.565.10 200 359 5.8E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 305 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 277 291 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 349 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 330 3.4E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 SMART SM00387 240 352 1.6E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 SUPERFAMILY SSF55874 185 348 2.1E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23125 b241179a74089eba8c12f9e3a85f42d6 360 SMART SM00388 130 196 1.8E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 Gene3D G3DSA:3.30.565.10 313 472 6.8E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SMART SM00304 198 250 1.7E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 318 3.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SMART SM00388 251 318 5.5E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 470 4.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SUPERFAMILY SSF47384 234 319 3.34E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 Pfam PF00672 HAMP domain 198 245 2.9E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 1.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 1.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 1.5E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SUPERFAMILY SSF158472 199 245 2.75E-10 T 29-03-2018 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SMART SM00387 364 472 7.8E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 Gene3D G3DSA:3.30.450.20 39 171 2.1E-16 T 29-03-2018 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SUPERFAMILY SSF55874 308 470 8.51E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 Gene3D G3DSA:1.10.287.130 241 312 5.0E-16 T 29-03-2018 A616_RS02400 f0586c82e49ed882a46c26e2506a9420 474 SUPERFAMILY SSF103190 83 173 8.24E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS22775 97ddea9ff63587805ded1328d5327f8f 196 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 9 186 8.3E-7 T 29-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 A616_RS22775 97ddea9ff63587805ded1328d5327f8f 196 Gene3D G3DSA:3.40.50.1000 51 190 5.3E-24 T 29-03-2018 IPR023214 HAD-like domain A616_RS22775 97ddea9ff63587805ded1328d5327f8f 196 SUPERFAMILY SSF56784 8 20 9.79E-16 T 29-03-2018 IPR023214 HAD-like domain A616_RS22775 97ddea9ff63587805ded1328d5327f8f 196 SUPERFAMILY SSF56784 66 166 9.79E-16 T 29-03-2018 IPR023214 HAD-like domain A616_RS22775 97ddea9ff63587805ded1328d5327f8f 196 PIRSF PIRSF021362 6 195 3.1E-51 T 29-03-2018 IPR009206 Nucleotidase, putative A616_RS14380 7c208d7cbed023d04c4284c617008734 201 SUPERFAMILY SSF48498 92 200 4.79E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS14380 7c208d7cbed023d04c4284c617008734 201 Gene3D G3DSA:1.10.357.10 78 201 2.2E-19 T 29-03-2018 A616_RS14380 7c208d7cbed023d04c4284c617008734 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14380 7c208d7cbed023d04c4284c617008734 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS14380 7c208d7cbed023d04c4284c617008734 201 Gene3D G3DSA:1.10.260.40 53 77 6.7E-6 T 29-03-2018 A616_RS14380 7c208d7cbed023d04c4284c617008734 201 Gene3D G3DSA:1.10.10.60 4 52 1.2E-14 T 29-03-2018 A616_RS14380 7c208d7cbed023d04c4284c617008734 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14380 7c208d7cbed023d04c4284c617008734 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14380 7c208d7cbed023d04c4284c617008734 201 SUPERFAMILY SSF46689 10 91 7.18E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 Pfam PF02803 Thiolase, C-terminal domain 273 395 1.8E-52 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 SUPERFAMILY SSF53901 6 272 1.25E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 394 1.6E-149 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 Pfam PF00108 Thiolase, N-terminal domain 6 265 4.9E-105 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 SUPERFAMILY SSF53901 273 394 1.6E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 PIRSF PIRSF000429 1 396 2.5E-135 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 Gene3D G3DSA:3.40.47.10 166 267 2.1E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 Gene3D G3DSA:3.40.47.10 1 165 5.9E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS29945 4c6d2cbc6b22b3270d8c597a3fba39a1 396 Gene3D G3DSA:3.40.47.10 268 393 6.5E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS05780 4261d9c9d309c781b8b45e983730b4de 181 Gene3D G3DSA:2.30.110.10 5 170 1.8E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS05780 4261d9c9d309c781b8b45e983730b4de 181 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 161 4.2E-27 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related A616_RS05780 4261d9c9d309c781b8b45e983730b4de 181 SUPERFAMILY SSF50475 3 164 1.65E-42 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 Gene3D G3DSA:3.40.50.1010 1 183 3.4E-36 T 29-03-2018 IPR029060 PIN domain-like A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 SUPERFAMILY SSF88723 3 64 3.34E-11 T 29-03-2018 IPR029060 PIN domain-like A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 SUPERFAMILY SSF88723 94 149 3.34E-11 T 29-03-2018 IPR029060 PIN domain-like A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 SUPERFAMILY SSF52540 234 424 1.5E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 Pfam PF13638 PIN domain 5 147 3.2E-34 T 29-03-2018 IPR002716 PIN domain A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 Pfam PF02562 PhoH-like protein 235 438 1.2E-54 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 Gene3D G3DSA:3.40.50.300 234 441 1.8E-22 T 29-03-2018 A616_RS21480 b12b46d95f746e27b7f5640ab77d1bbc 444 SMART SM00670 3 135 6.7E-21 T 29-03-2018 IPR002716 PIN domain A616_RS09840 6c35dbd505eb6cff3466e23ff9e0ff1e 307 SUPERFAMILY SSF161098 76 233 1.7E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09840 6c35dbd505eb6cff3466e23ff9e0ff1e 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 273 8.2E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09840 6c35dbd505eb6cff3466e23ff9e0ff1e 307 Gene3D G3DSA:1.10.3720.10 1 291 5.5E-23 T 29-03-2018 A616_RS25865 90a3937b3fb8c1e0b3b74c5dbaac13c2 333 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 6 258 6.5E-37 T 29-03-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 A616_RS25865 90a3937b3fb8c1e0b3b74c5dbaac13c2 333 Gene3D G3DSA:3.40.50.720 1 332 3.2E-66 T 29-03-2018 A616_RS25865 90a3937b3fb8c1e0b3b74c5dbaac13c2 333 SUPERFAMILY SSF51735 1 266 7.89E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS25865 90a3937b3fb8c1e0b3b74c5dbaac13c2 333 SUPERFAMILY SSF51735 296 330 7.89E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS03835 3b28fdbbaeae14b5a728258bbdf59f35 193 SUPERFAMILY SSF53955 53 185 1.01E-35 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS03835 3b28fdbbaeae14b5a728258bbdf59f35 193 Pfam PF01464 Transglycosylase SLT domain 73 170 1.6E-28 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 A616_RS03835 3b28fdbbaeae14b5a728258bbdf59f35 193 Gene3D G3DSA:1.10.530.10 31 188 5.4E-33 T 29-03-2018 A616_RS12850 e205bd2bcc587f956f4038b1895ebabd 151 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 15 118 1.7E-22 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A616_RS12850 e205bd2bcc587f956f4038b1895ebabd 151 SUPERFAMILY SSF158622 7 128 1.57E-31 T 29-03-2018 IPR023378 YheA/YmcA-like domain A616_RS12850 e205bd2bcc587f956f4038b1895ebabd 151 Gene3D G3DSA:1.20.1500.10 11 120 3.8E-28 T 29-03-2018 IPR023378 YheA/YmcA-like domain A616_RS27805 1f5a37461ef5865ae7fcb9e8a4ac7adb 441 SUPERFAMILY SSF53850 50 431 1.25E-53 T 29-03-2018 A616_RS27805 1f5a37461ef5865ae7fcb9e8a4ac7adb 441 Pfam PF13416 Bacterial extracellular solute-binding protein 66 372 1.3E-36 T 29-03-2018 A616_RS27805 1f5a37461ef5865ae7fcb9e8a4ac7adb 441 Gene3D G3DSA:3.40.190.10 39 202 7.4E-30 T 29-03-2018 A616_RS27805 1f5a37461ef5865ae7fcb9e8a4ac7adb 441 Gene3D G3DSA:3.40.190.10 203 373 4.9E-7 T 29-03-2018 A616_RS01960 53d95c091e36fe4a4717b0a763db5fb0 203 SUPERFAMILY SSF53474 2 200 1.79E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01960 53d95c091e36fe4a4717b0a763db5fb0 203 Pfam PF01738 Dienelactone hydrolase family 76 183 1.2E-10 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 A616_RS01960 53d95c091e36fe4a4717b0a763db5fb0 203 Gene3D G3DSA:3.40.50.1820 1 201 6.1E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 SUPERFAMILY SSF56420 2 150 4.58E-60 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 Gene3D G3DSA:3.90.45.10 1 157 1.8E-60 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 Pfam PF01327 Polypeptide deformylase 4 148 7.6E-53 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 PRINTS PR01576 Peptide deformylase signature 87 98 2.6E-34 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 PRINTS PR01576 Peptide deformylase signature 33 62 2.6E-34 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 PRINTS PR01576 Peptide deformylase signature 99 117 2.6E-34 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 PRINTS PR01576 Peptide deformylase signature 118 147 2.6E-34 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 PIRSF PIRSF004749 1 156 6.5E-54 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 Hamap MF_00163 Peptide deformylase [def]. 2 158 29.902 T 29-03-2018 IPR023635 Peptide deformylase A616_RS20785 597353653e5b18fdc7aaa4ed1c83658f 158 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 155 1.8E-52 T 29-03-2018 IPR023635 Peptide deformylase A616_RS21705 7900b00a42c4ad56664916c880070fd0 302 SUPERFAMILY SSF103481 201 282 2.88E-8 T 29-03-2018 A616_RS21705 7900b00a42c4ad56664916c880070fd0 302 Pfam PF00892 EamA-like transporter family 4 139 2.7E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS21705 7900b00a42c4ad56664916c880070fd0 302 TIGRFAM TIGR00688 rarD: protein RarD 3 255 5.8E-73 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 A616_RS21705 7900b00a42c4ad56664916c880070fd0 302 SUPERFAMILY SSF103481 43 140 3.66E-10 T 29-03-2018 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 Gene3D G3DSA:3.40.47.10 262 413 1.6E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 Gene3D G3DSA:3.40.47.10 5 259 1.0E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 PIRSF PIRSF000447 1 413 6.7E-199 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 SUPERFAMILY SSF53901 214 411 1.71E-76 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 368 7.3E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 409 5.8E-207 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 1.1E-63 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 SUPERFAMILY SSF53901 2 251 1.71E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS20275 c0bda18d1d4f115a992d4effcbc5a48a 413 SMART SM00825 Beta-ketoacyl synthase 5 413 5.3E-18 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS19750 dd8d2afa1401851c18e9b3f126897d46 86 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 75 3.5E-25 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH A616_RS19750 dd8d2afa1401851c18e9b3f126897d46 86 SUPERFAMILY SSF50346 1 74 2.67E-12 T 29-03-2018 IPR011033 PRC-barrel-like A616_RS19750 dd8d2afa1401851c18e9b3f126897d46 86 Gene3D G3DSA:2.30.30.240 1 78 1.8E-17 T 29-03-2018 A616_RS19750 dd8d2afa1401851c18e9b3f126897d46 86 Pfam PF05239 PRC-barrel domain 1 75 4.4E-15 T 29-03-2018 IPR027275 PRC-barrel domain A616_RS02935 bdc10bf823c4dc4dc1ca6c546725fa23 153 SMART SM00731 4 149 7.4E-50 T 29-03-2018 IPR006640 SprT-like A616_RS02935 bdc10bf823c4dc4dc1ca6c546725fa23 153 Hamap MF_00745 Protein SprT-like. 4 149 38.095 T 29-03-2018 IPR023524 Uncharacterised protein family SprT-like A616_RS02935 bdc10bf823c4dc4dc1ca6c546725fa23 153 Pfam PF10263 SprT-like family 8 98 1.3E-13 T 29-03-2018 IPR006640 SprT-like A616_RS20300 47c8ebdf6069ed928a02c96eed12da8e 335 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 328 5.9E-125 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A616_RS20300 47c8ebdf6069ed928a02c96eed12da8e 335 PIRSF PIRSF002465 1 333 9.6E-126 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A616_RS20300 47c8ebdf6069ed928a02c96eed12da8e 335 Pfam PF02504 Fatty acid synthesis protein 1 320 2.9E-119 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 A616_RS20300 47c8ebdf6069ed928a02c96eed12da8e 335 Gene3D G3DSA:3.40.718.10 1 331 2.4E-112 T 29-03-2018 A616_RS20300 47c8ebdf6069ed928a02c96eed12da8e 335 SUPERFAMILY SSF53659 2 329 2.84E-104 T 29-03-2018 A616_RS20300 47c8ebdf6069ed928a02c96eed12da8e 335 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 146.584 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 81 99 7.9E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 7.9E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 99 125 7.9E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 151 179 7.9E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 237 17.764 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 223 5.0E-61 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS03005 27906fbb1cb38e8a34a0a7f08c890c6f 258 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 218 3.7E-56 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS02700 c4ed1ee9a4e0ffa94f835f0806567d24 279 Gene3D G3DSA:3.40.190.10 161 279 4.3E-47 T 29-03-2018 A616_RS02700 c4ed1ee9a4e0ffa94f835f0806567d24 279 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 42 277 3.8E-70 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS02700 c4ed1ee9a4e0ffa94f835f0806567d24 279 Gene3D G3DSA:3.40.190.10 43 160 3.1E-44 T 29-03-2018 A616_RS02700 c4ed1ee9a4e0ffa94f835f0806567d24 279 SUPERFAMILY SSF53850 43 279 8.69E-86 T 29-03-2018 A616_RS02700 c4ed1ee9a4e0ffa94f835f0806567d24 279 Pfam PF03180 NLPA lipoprotein 44 279 1.4E-100 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS02700 c4ed1ee9a4e0ffa94f835f0806567d24 279 PIRSF PIRSF002854 1 279 7.4E-108 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 90 8.4E-8 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 SUPERFAMILY SSF52540 94 361 6.3E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 11 433 2.3E-184 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 23 433 2.4E-200 T 29-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 346 355 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 355 2.1E-77 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 SMART SM00382 158 340 2.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20025 bf32da3fb3a1e2fdd43b63b536d9e68d 439 Gene3D G3DSA:3.40.50.300 92 362 5.7E-83 T 29-03-2018 A616_RS23085 5d898da6cb8861a39e7f75d713a417a4 393 Gene3D G3DSA:3.40.640.10 43 280 1.3E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS23085 5d898da6cb8861a39e7f75d713a417a4 393 Gene3D G3DSA:3.90.1150.10 281 386 1.9E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS23085 5d898da6cb8861a39e7f75d713a417a4 393 Pfam PF00155 Aminotransferase class I and II 33 383 6.4E-60 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS23085 5d898da6cb8861a39e7f75d713a417a4 393 SUPERFAMILY SSF53383 4 386 9.08E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS04335 8777a10350aa165e1c03adb6b3e4f380 312 SUPERFAMILY SSF53590 1 309 2.22E-84 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS04335 8777a10350aa165e1c03adb6b3e4f380 312 Gene3D G3DSA:3.90.245.10 2 312 1.1E-67 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS04335 8777a10350aa165e1c03adb6b3e4f380 312 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 302 2.7E-47 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 Gene3D G3DSA:3.40.190.10 88 175 2.1E-24 T 29-03-2018 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 Pfam PF03466 LysR substrate binding domain 88 291 3.0E-53 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 Gene3D G3DSA:1.10.10.10 1 83 1.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 SUPERFAMILY SSF53850 88 293 3.48E-46 T 29-03-2018 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 Gene3D G3DSA:3.40.190.10 176 267 1.6E-28 T 29-03-2018 A616_RS14115 e5ab78ec95790b7c5420801dee8a0746 295 SUPERFAMILY SSF46785 1 84 3.12E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 Gene3D G3DSA:3.30.465.10 89 217 9.9E-35 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 300 89.428 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 SUPERFAMILY SSF56194 196 299 9.02E-36 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 Gene3D G3DSA:3.90.78.10 218 300 4.7E-28 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 SUPERFAMILY SSF56176 20 207 3.53E-43 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 Pfam PF01565 FAD binding domain 34 162 5.8E-22 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 Gene3D G3DSA:3.30.43.10 8 83 2.3E-25 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 298 5.9E-76 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21910 9a9bf148c412da0b01cbbcd30e73f13d 300 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 202 297 9.5E-30 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS13620 34aa017b303e9f209e2e518e1f3ca124 455 Gene3D G3DSA:3.30.30.80 219 255 0.0015 T 29-03-2018 A616_RS13620 34aa017b303e9f209e2e518e1f3ca124 455 Pfam PF14620 YpeB sporulation 17 377 4.6E-138 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 A616_RS13620 34aa017b303e9f209e2e518e1f3ca124 455 Pfam PF03413 Peptidase propeptide and YPEB domain 382 439 0.0035 T 29-03-2018 IPR025711 PepSY domain A616_RS13620 34aa017b303e9f209e2e518e1f3ca124 455 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 13 445 9.7E-141 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 A616_RS22755 f08aad4ccc6335950c7f9264df22f59c 389 Pfam PF00266 Aminotransferase class-V 2 364 3.4E-81 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS22755 f08aad4ccc6335950c7f9264df22f59c 389 SUPERFAMILY SSF53383 1 372 3.5E-108 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS22755 f08aad4ccc6335950c7f9264df22f59c 389 Gene3D G3DSA:3.40.640.10 11 255 3.9E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS22755 f08aad4ccc6335950c7f9264df22f59c 389 Gene3D G3DSA:3.90.1150.10 262 379 6.0E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS22755 f08aad4ccc6335950c7f9264df22f59c 389 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A616_RS22755 f08aad4ccc6335950c7f9264df22f59c 389 PIRSF PIRSF005572 1 378 3.3E-125 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A616_RS02440 d20a1b4f635e5743f0a99806d65d1ee3 519 Pfam PF13439 Glycosyltransferase Family 4 19 170 2.6E-9 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS02440 d20a1b4f635e5743f0a99806d65d1ee3 519 Pfam PF00534 Glycosyl transferases group 1 181 341 4.9E-40 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS02440 d20a1b4f635e5743f0a99806d65d1ee3 519 Gene3D G3DSA:3.40.50.2000 10 179 2.5E-7 T 29-03-2018 A616_RS02440 d20a1b4f635e5743f0a99806d65d1ee3 519 SUPERFAMILY SSF53756 13 362 3.49E-70 T 29-03-2018 A616_RS02440 d20a1b4f635e5743f0a99806d65d1ee3 519 Gene3D G3DSA:3.40.50.2000 180 348 5.5E-43 T 29-03-2018 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Gene3D G3DSA:2.60.260.20 196 253 6.2E-13 T 29-03-2018 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 371 41.143 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Pfam PF00226 DnaJ domain 4 65 2.3E-26 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Gene3D G3DSA:2.60.260.20 254 365 1.6E-30 T 29-03-2018 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Pfam PF01556 DnaJ C terminal domain 116 332 2.8E-41 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 SUPERFAMILY SSF46565 2 100 3.4E-35 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 SUPERFAMILY SSF49493 257 343 3.4E-25 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 348 8.1E-143 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 SUPERFAMILY SSF57938 129 209 2.35E-17 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Pfam PF00684 DnaJ central domain 142 206 9.5E-13 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 PRINTS PR00625 DnaJ domain signature 60 79 7.2E-31 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 PRINTS PR00625 DnaJ domain signature 6 24 7.2E-31 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 PRINTS PR00625 DnaJ domain signature 24 39 7.2E-31 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 PRINTS PR00625 DnaJ domain signature 40 60 7.2E-31 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Gene3D G3DSA:1.10.287.110 1 110 5.1E-37 T 29-03-2018 IPR001623 DnaJ domain A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 SUPERFAMILY SSF49493 109 164 4.19E-18 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 SUPERFAMILY SSF49493 212 260 4.19E-18 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 Gene3D G3DSA:2.10.230.10 139 195 2.6E-16 T 29-03-2018 A616_RS11475 a2ddd3256d964c596e64f8f545980173 375 SMART SM00271 3 60 1.7E-28 T 29-03-2018 IPR001623 DnaJ domain A616_RS15375 e9101c0c5e26df7fd570d69a34dfa65a 393 Pfam PF02515 CoA-transferase family III 4 367 7.6E-99 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 A616_RS15375 e9101c0c5e26df7fd570d69a34dfa65a 393 Gene3D G3DSA:3.40.50.10540 1 392 2.0E-125 T 29-03-2018 IPR023606 CoA-transferase family III domain A616_RS15375 e9101c0c5e26df7fd570d69a34dfa65a 393 SUPERFAMILY SSF89796 2 390 3.53E-120 T 29-03-2018 IPR023606 CoA-transferase family III domain A616_RS27190 0f9a2f58b9c0604d643ffbc308c87687 412 Pfam PF13556 PucR C-terminal helix-turn-helix domain 347 405 7.6E-22 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS27190 0f9a2f58b9c0604d643ffbc308c87687 412 Gene3D G3DSA:3.30.450.40 11 148 2.7E-11 T 29-03-2018 IPR029016 GAF domain-like A616_RS27190 0f9a2f58b9c0604d643ffbc308c87687 412 Gene3D G3DSA:1.10.10.60 330 383 1.5E-9 T 29-03-2018 A616_RS05150 542b5e9bc3ec7c62b66e47242157e54d 235 SMART SM00479 52 221 5.8E-31 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS05150 542b5e9bc3ec7c62b66e47242157e54d 235 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 53 221 4.7E-24 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS05150 542b5e9bc3ec7c62b66e47242157e54d 235 Gene3D G3DSA:3.30.420.10 49 234 4.0E-35 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS05150 542b5e9bc3ec7c62b66e47242157e54d 235 Pfam PF00929 Exonuclease 54 208 4.3E-22 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A616_RS05150 542b5e9bc3ec7c62b66e47242157e54d 235 SUPERFAMILY SSF53098 45 219 2.7E-46 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS28245 09af8597911d5644d0c4aae27b1849a6 84 Pfam PF04023 FeoA domain 7 75 1.7E-15 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A616_RS28245 09af8597911d5644d0c4aae27b1849a6 84 Gene3D G3DSA:2.30.30.90 5 84 3.8E-17 T 29-03-2018 A616_RS28245 09af8597911d5644d0c4aae27b1849a6 84 SUPERFAMILY SSF50037 13 78 2.04E-17 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal A616_RS28245 09af8597911d5644d0c4aae27b1849a6 84 SMART SM00899 6 78 7.3E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 SUPERFAMILY SSF88946 22 116 9.26E-18 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 SUPERFAMILY SSF88659 182 259 1.18E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 Gene3D G3DSA:1.10.10.10 118 167 2.7E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 SUPERFAMILY SSF88659 123 178 8.72E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 Gene3D G3DSA:1.10.1740.10 25 115 2.5E-12 T 29-03-2018 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 Gene3D G3DSA:1.10.10.60 217 260 1.3E-5 T 29-03-2018 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 Pfam PF04542 Sigma-70 region 2 43 114 1.1E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03840 ef67173c2daf74b0edc1868664bc20c3 268 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 260 1.0E-13 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25715 63991e11befb46f28c3cfa42b495434e 157 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 11 152 2.7E-16 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 A616_RS07750 09640ade8476c3b5962e502df139363e 274 Gene3D G3DSA:1.10.3720.10 8 263 2.4E-43 T 29-03-2018 A616_RS07750 09640ade8476c3b5962e502df139363e 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 262 1.3E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07750 09640ade8476c3b5962e502df139363e 274 SUPERFAMILY SSF161098 8 274 3.18E-74 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS00615 684754a172fec49efdf8f2151ce247f4 82 Gene3D G3DSA:2.10.260.10 2 49 1.9E-20 T 29-03-2018 A616_RS00615 684754a172fec49efdf8f2151ce247f4 82 SMART SM00966 9 52 2.6E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A616_RS00615 684754a172fec49efdf8f2151ce247f4 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.4E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A616_RS00615 684754a172fec49efdf8f2151ce247f4 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 49 1.5E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A616_RS00615 684754a172fec49efdf8f2151ce247f4 82 SUPERFAMILY SSF89447 2 54 4.97E-17 T 29-03-2018 A616_RS12990 a902854b8e1debbeb242ab83182b7583 170 Pfam PF11085 Conserved membrane protein YqhR 18 164 1.4E-10 T 29-03-2018 IPR024563 Uncharacterised protein family YqhR A616_RS12990 a902854b8e1debbeb242ab83182b7583 170 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 22 163 1.0E-5 T 29-03-2018 IPR024563 Uncharacterised protein family YqhR A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 SMART SM00866 95 233 4.1E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 SUPERFAMILY SSF64288 62 239 6.28E-41 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 2.5E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 Gene3D G3DSA:3.40.1410.10 74 241 3.1E-35 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 Pfam PF07702 UTRA domain 96 232 1.0E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 SUPERFAMILY SSF46785 8 77 2.43E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 SMART SM00345 14 73 6.0E-26 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 Gene3D G3DSA:1.10.10.10 4 73 8.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 8.7E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS19700 0e77e2de15c339a7365c7e4874cc2f06 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 8.7E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 Pfam PF01025 GrpE 18 180 2.1E-53 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 SUPERFAMILY SSF51064 126 180 2.09E-18 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 PRINTS PR00773 GrpE protein signature 50 66 1.3E-29 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 PRINTS PR00773 GrpE protein signature 78 93 1.3E-29 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 PRINTS PR00773 GrpE protein signature 159 178 1.3E-29 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 PRINTS PR00773 GrpE protein signature 132 147 1.3E-29 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 Hamap MF_01151 Protein GrpE [grpE]. 2 180 20.591 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 ProSitePatterns PS01071 grpE protein signature. 135 178 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 SUPERFAMILY SSF58014 30 124 6.93E-27 T 29-03-2018 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 Gene3D G3DSA:2.30.22.10 124 179 1.1E-20 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A616_RS11465 0a8d2159357a8be65752ea51a5232483 180 Gene3D G3DSA:3.90.20.20 14 122 6.0E-28 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A616_RS28270 6186e10300eedfc334ae18db2619c019 246 Gene3D G3DSA:3.40.630.30 5 214 3.2E-15 T 29-03-2018 A616_RS28270 6186e10300eedfc334ae18db2619c019 246 SUPERFAMILY SSF55729 32 146 2.27E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS28270 6186e10300eedfc334ae18db2619c019 246 Pfam PF00583 Acetyltransferase (GNAT) family 55 147 3.2E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS06225 06cde6e65fbfac800c1788a8c457208e 335 Gene3D G3DSA:1.10.10.10 21 110 0.0016 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28480 286ad6b0ef1de337ee85a7b35680cc9e 260 SUPERFAMILY SSF89372 35 180 6.67E-5 T 29-03-2018 A616_RS28480 286ad6b0ef1de337ee85a7b35680cc9e 260 Gene3D G3DSA:1.25.40.10 36 260 1.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS19780 d1960514eb85d2112012c1d999ac098d 308 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 4 217 1.9E-78 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS19780 d1960514eb85d2112012c1d999ac098d 308 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 26 180 1.8E-56 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A616_RS19780 d1960514eb85d2112012c1d999ac098d 308 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 4 304 19.146 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS19780 d1960514eb85d2112012c1d999ac098d 308 Gene3D G3DSA:3.30.2350.10 3 229 2.8E-82 T 29-03-2018 A616_RS19780 d1960514eb85d2112012c1d999ac098d 308 SUPERFAMILY SSF55120 4 223 1.92E-80 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS19780 d1960514eb85d2112012c1d999ac098d 308 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 234 1.9E-14 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A616_RS27590 3f2028fd8cf8b68ce13db6b25ffa641c 502 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 14 481 1.9E-189 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS27590 3f2028fd8cf8b68ce13db6b25ffa641c 502 PIRSF PIRSF005690 1 496 3.5E-185 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS10540 83a0db72dfd25077bffa54ee55ee05d0 278 Pfam PF02163 Peptidase family M50 115 164 6.4E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A616_RS10540 83a0db72dfd25077bffa54ee55ee05d0 278 Pfam PF02163 Peptidase family M50 33 104 5.0E-8 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 SUPERFAMILY SSF52374 4 168 9.78E-17 T 29-03-2018 A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 PIRSF PIRSF004776 2 348 6.4E-85 T 29-03-2018 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22 A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 Pfam PF13521 AAA domain 169 328 6.1E-33 T 29-03-2018 A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 Gene3D G3DSA:3.40.50.300 169 333 1.2E-13 T 29-03-2018 A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 Gene3D G3DSA:3.40.50.620 2 168 2.2E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 70 2.0E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS08950 7da914b8f492e200bbf4bec10aab557b 352 SUPERFAMILY SSF52540 166 335 1.37E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24910 bf38abd8505b1f4f33b4f5c4675cbcc6 204 Pfam PF08000 Bacterial PH domain 15 132 5.9E-35 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain A616_RS24910 bf38abd8505b1f4f33b4f5c4675cbcc6 204 Gene3D G3DSA:2.30.29.50 21 112 2.2E-29 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain A616_RS24910 bf38abd8505b1f4f33b4f5c4675cbcc6 204 Gene3D G3DSA:1.10.287.210 116 204 1.5E-32 T 29-03-2018 A616_RS24910 bf38abd8505b1f4f33b4f5c4675cbcc6 204 Pfam PF11724 YvbH-like oligomerisation region 144 204 1.3E-26 T 29-03-2018 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain A616_RS24910 bf38abd8505b1f4f33b4f5c4675cbcc6 204 SUPERFAMILY SSF50729 15 203 2.83E-67 T 29-03-2018 IPR011993 PH domain-like A616_RS13675 a1ce6b3327a90a1de46dcc63e4f6da8c 200 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 183 2.6E-51 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A616_RS13675 a1ce6b3327a90a1de46dcc63e4f6da8c 200 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 192 20.124 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A616_RS13675 a1ce6b3327a90a1de46dcc63e4f6da8c 200 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 192 1.3E-52 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A616_RS13675 a1ce6b3327a90a1de46dcc63e4f6da8c 200 SMART SM01207 7 184 5.8E-79 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A616_RS12440 747fb6848c4b847e584f9bb9b9db2150 191 SUPERFAMILY SSF52141 9 175 4.8E-37 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS12440 747fb6848c4b847e584f9bb9b9db2150 191 Gene3D G3DSA:3.40.470.10 11 187 9.5E-48 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS12440 747fb6848c4b847e584f9bb9b9db2150 191 Pfam PF03167 Uracil DNA glycosylase superfamily 13 168 5.2E-19 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS26350 311e71efe66a62d344670edb91f122f9 400 SUPERFAMILY SSF52540 117 366 6.69E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26350 311e71efe66a62d344670edb91f122f9 400 Gene3D G3DSA:1.10.8.60 296 385 1.7E-14 T 29-03-2018 A616_RS26350 311e71efe66a62d344670edb91f122f9 400 ProSitePatterns PS00674 AAA-protein family signature. 258 276 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A616_RS26350 311e71efe66a62d344670edb91f122f9 400 SUPERFAMILY SSF48452 3 38 5.06E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS26350 311e71efe66a62d344670edb91f122f9 400 Gene3D G3DSA:1.25.40.10 1 98 1.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS26350 311e71efe66a62d344670edb91f122f9 400 SMART SM00382 153 290 3.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS26350 311e71efe66a62d344670edb91f122f9 400 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 157 287 5.8E-40 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS26350 311e71efe66a62d344670edb91f122f9 400 Gene3D G3DSA:3.40.50.300 110 295 1.4E-50 T 29-03-2018 A616_RS19330 0f93b0c8e26657a8aba7e99971ba4ea6 109 SUPERFAMILY SSF46955 43 97 8.97E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS19330 0f93b0c8e26657a8aba7e99971ba4ea6 109 Gene3D G3DSA:1.10.10.10 44 104 5.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19330 0f93b0c8e26657a8aba7e99971ba4ea6 109 Pfam PF12728 Helix-turn-helix domain 44 98 3.2E-11 T 29-03-2018 A616_RS19330 0f93b0c8e26657a8aba7e99971ba4ea6 109 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 44 98 3.9E-12 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 Pfam PF08402 TOBE domain 249 326 2.3E-10 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 SMART SM00382 29 212 4.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 35 242 1.4E-108 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 SUPERFAMILY SSF50331 232 326 6.8E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 Pfam PF00005 ABC transporter 23 162 1.5E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 SUPERFAMILY SSF52540 4 241 6.88E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS24365 43aaf4847d9909afc7b158a5981918c8 328 Gene3D G3DSA:3.40.50.300 1 270 2.9E-75 T 29-03-2018 A616_RS20050 ea9dde8e68ae6a8fb8930050dfe051d9 152 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 103 150 2.3E-13 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A616_RS20050 ea9dde8e68ae6a8fb8930050dfe051d9 152 Pfam PF00460 Flagella basal body rod protein 7 35 2.3E-8 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A616_RS20050 ea9dde8e68ae6a8fb8930050dfe051d9 152 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 151 3.4E-48 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 A616_RS20050 ea9dde8e68ae6a8fb8930050dfe051d9 152 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 SMART SM00382 87 241 2.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 2.0E-199 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 44.026 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 SUPERFAMILY SSF52540 65 290 1.52E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 Gene3D G3DSA:3.40.50.300 69 279 8.5E-44 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 SUPERFAMILY SSF54211 252 266 1.74E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 SUPERFAMILY SSF54211 300 451 1.74E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 Gene3D G3DSA:3.30.230.10 280 454 1.8E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 Pfam PF13481 AAA domain 70 219 3.7E-17 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 171 195 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 210 238 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 79 107 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 10 34 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 121 138 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 245 271 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 PRINTS PR01874 DNA repair protein radA signature 319 342 2.6E-91 T 29-03-2018 A616_RS01235 7fe4880e4ba62034350fa61df825e766 455 Pfam PF13541 Subunit ChlI of Mg-chelatase 329 427 1.6E-11 T 29-03-2018 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 Pfam PF02803 Thiolase, C-terminal domain 269 390 1.2E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 SUPERFAMILY SSF53901 269 390 5.98E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 Pfam PF00108 Thiolase, N-terminal domain 4 260 7.6E-84 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 Gene3D G3DSA:3.40.47.10 1 266 2.9E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 6.0E-142 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 PIRSF PIRSF000429 1 391 2.0E-132 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 SUPERFAMILY SSF53901 4 268 3.04E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS09690 afeb4531893ac442a79a169b5905cc1f 391 Gene3D G3DSA:3.40.47.10 267 388 7.5E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 SUPERFAMILY SSF51055 32 74 2.62E-14 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 SUPERFAMILY SSF49265 83 170 6.75E-18 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 Pfam PF00704 Glycosyl hydrolases family 18 183 486 5.2E-29 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 Gene3D G3DSA:2.60.40.10 77 170 4.6E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 SUPERFAMILY SSF51445 180 496 1.22E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 ProSitePatterns PS01095 Chitinases family 18 active site. 285 293 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 SMART SM00636 181 486 2.0E-6 T 29-03-2018 IPR011583 Chitinase II GO:0008061 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 Pfam PF00041 Fibronectin type III domain 87 162 2.4E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 Gene3D G3DSA:3.20.20.80 175 506 1.1E-53 T 29-03-2018 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 Gene3D G3DSA:2.10.10.20 32 74 5.8E-14 T 29-03-2018 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 SMART SM00060 85 158 3.2E-11 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS01780 031708c4fd3c4ef746cf1e2d214a5ba6 506 SMART SM00495 29 75 7.5E-10 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS02600 8924383de45af687f047afc6649d18e5 408 Gene3D G3DSA:1.20.1250.20 218 403 8.5E-19 T 29-03-2018 A616_RS02600 8924383de45af687f047afc6649d18e5 408 Pfam PF05977 Transmembrane secretion effector 12 397 6.7E-30 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS02600 8924383de45af687f047afc6649d18e5 408 SUPERFAMILY SSF103473 13 403 7.32E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02600 8924383de45af687f047afc6649d18e5 408 Gene3D G3DSA:1.20.1250.20 6 208 2.3E-18 T 29-03-2018 A616_RS24605 ff149896471d654e9a144452d3dce91f 679 Pfam PF00092 von Willebrand factor type A domain 46 231 5.6E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS24605 ff149896471d654e9a144452d3dce91f 679 Gene3D G3DSA:2.60.40.10 332 439 0.059 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS24605 ff149896471d654e9a144452d3dce91f 679 Gene3D G3DSA:3.40.50.410 40 242 5.8E-36 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS24605 ff149896471d654e9a144452d3dce91f 679 Gene3D G3DSA:2.60.40.10 440 529 1.5E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS24605 ff149896471d654e9a144452d3dce91f 679 SMART SM00327 44 237 8.0E-27 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS24605 ff149896471d654e9a144452d3dce91f 679 SUPERFAMILY SSF53300 45 235 5.63E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 Gene3D G3DSA:3.10.350.10 236 290 1.6E-8 T 29-03-2018 A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 SMART SM01208 295 373 1.5E-22 T 29-03-2018 IPR011098 G5 domain A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 Pfam PF01476 LysM domain 243 286 8.1E-6 T 29-03-2018 IPR018392 LysM domain A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 Gene3D G3DSA:2.70.70.10 370 498 2.8E-39 T 29-03-2018 A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 SUPERFAMILY SSF51261 300 497 5.75E-54 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 SMART SM00257 242 287 1.7E-4 T 29-03-2018 IPR018392 LysM domain A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 Pfam PF07501 G5 domain 298 372 1.2E-19 T 29-03-2018 IPR011098 G5 domain A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 Gene3D G3DSA:2.20.230.10 294 369 1.6E-17 T 29-03-2018 A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 SUPERFAMILY SSF54106 241 286 3.4E-6 T 29-03-2018 IPR018392 LysM domain A616_RS32135 378f5e59776956de22edfd9c9f67ac55 498 Pfam PF01551 Peptidase family M23 401 493 1.1E-29 T 29-03-2018 IPR016047 Peptidase M23 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 Pfam PF14559 Tetratricopeptide repeat 362 419 1.7E-6 T 29-03-2018 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 SUPERFAMILY SSF46565 2 46 6.15E-7 T 29-03-2018 IPR001623 DnaJ domain A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 Gene3D G3DSA:1.25.40.10 44 341 6.8E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 Gene3D G3DSA:1.25.40.10 342 433 1.8E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 Gene3D G3DSA:1.10.287.110 2 43 1.2E-5 T 29-03-2018 IPR001623 DnaJ domain A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 SMART SM00028 347 380 120.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 SMART SM00028 381 414 0.11 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 SMART SM00028 279 312 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 SMART SM00028 313 346 0.11 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31895 3466e6585dfd8f53f3f2d06f1d972576 690 SUPERFAMILY SSF48452 302 424 1.88E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 Pfam PF08281 Sigma-70, region 4 111 160 1.2E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 Pfam PF04542 Sigma-70 region 2 9 73 6.4E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 Gene3D G3DSA:1.10.10.10 73 163 4.9E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 SUPERFAMILY SSF54427 177 288 1.15E-10 T 29-03-2018 IPR032710 NTF2-like domain A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 SUPERFAMILY SSF88946 7 88 6.28E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 163 2.2E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 SUPERFAMILY SSF88659 109 162 2.62E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 Gene3D G3DSA:1.10.1740.10 3 72 6.5E-14 T 29-03-2018 A616_RS05770 02a1c3efe5112295e1ae1736f73d4448 295 Gene3D G3DSA:3.10.450.50 172 291 1.2E-9 T 29-03-2018 A616_RS22470 245eb9744fc133695b4d60978190ceb2 209 Pfam PF09335 SNARE associated Golgi protein 33 159 1.4E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 PRINTS PR00095 Anthranilate synthase component I signature 437 451 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 PRINTS PR00095 Anthranilate synthase component I signature 342 355 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 PRINTS PR00095 Anthranilate synthase component I signature 422 436 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 PRINTS PR00095 Anthranilate synthase component I signature 328 341 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 SUPERFAMILY SSF56322 25 491 4.71E-148 T 29-03-2018 IPR005801 ADC synthase GO:0009058 A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 Gene3D G3DSA:3.60.120.10 31 497 3.1E-161 T 29-03-2018 IPR005801 ADC synthase GO:0009058 A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 Pfam PF00425 chorismate binding enzyme 227 480 5.9E-101 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A616_RS01115 6c69016d6ea2507049f8f1d81d6f474c 497 Pfam PF04715 Anthranilate synthase component I, N terminal region 30 165 1.9E-32 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS12365 97877589399c5d1a0813c867a1fe9f98 220 SUPERFAMILY SSF100950 6 218 4.44E-60 T 29-03-2018 A616_RS12365 97877589399c5d1a0813c867a1fe9f98 220 Pfam PF01144 Coenzyme A transferase 10 199 1.9E-30 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS12365 97877589399c5d1a0813c867a1fe9f98 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 211 1.3E-79 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 A616_RS12365 97877589399c5d1a0813c867a1fe9f98 220 SMART SM00882 9 205 7.9E-40 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS12365 97877589399c5d1a0813c867a1fe9f98 220 Gene3D G3DSA:3.40.1080.10 6 217 2.6E-55 T 29-03-2018 A616_RS00480 9708621c7af2b3f3937afdf1e97a1737 199 SUPERFAMILY SSF53335 33 173 2.29E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS00480 9708621c7af2b3f3937afdf1e97a1737 199 Gene3D G3DSA:3.40.50.150 30 178 1.2E-16 T 29-03-2018 A616_RS00480 9708621c7af2b3f3937afdf1e97a1737 199 Pfam PF13649 Methyltransferase domain 54 151 1.3E-6 T 29-03-2018 A616_RS11505 348ec2ff117b075e3384607e8b1c93a8 131 Gene3D G3DSA:1.20.5.900 83 131 0.021 T 29-03-2018 A616_RS11505 348ec2ff117b075e3384607e8b1c93a8 131 Pfam PF03788 LrgA family 16 107 5.2E-27 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 SUPERFAMILY SSF46785 166 255 2.49E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 Gene3D G3DSA:3.30.450.40 1 158 7.8E-18 T 29-03-2018 IPR029016 GAF domain-like A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 Gene3D G3DSA:1.10.10.10 159 258 7.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 Pfam PF08222 CodY helix-turn-helix domain 197 256 5.2E-32 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 258 108.084 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 PIRSF PIRSF011572 1 256 1.1E-92 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 Pfam PF06018 CodY GAF-like domain 2 177 7.4E-51 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 A616_RS22855 74ca831f9e29a524a29fb1c3040fece9 258 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 252 3.7E-89 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A616_RS22795 64024ee15096503bd618f4f749e43a7d 406 Gene3D G3DSA:1.20.1250.20 1 189 1.0E-15 T 29-03-2018 A616_RS22795 64024ee15096503bd618f4f749e43a7d 406 Gene3D G3DSA:1.20.1250.20 200 397 2.6E-9 T 29-03-2018 A616_RS22795 64024ee15096503bd618f4f749e43a7d 406 Pfam PF07690 Major Facilitator Superfamily 14 349 7.6E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS22795 64024ee15096503bd618f4f749e43a7d 406 SUPERFAMILY SSF103473 8 397 1.44E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS28985 1dfa7e32f4db057ae55e78514f2b8b4e 250 Gene3D G3DSA:3.40.50.300 1 246 1.7E-55 T 29-03-2018 A616_RS28985 1dfa7e32f4db057ae55e78514f2b8b4e 250 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28985 1dfa7e32f4db057ae55e78514f2b8b4e 250 SMART SM00382 30 212 6.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28985 1dfa7e32f4db057ae55e78514f2b8b4e 250 Pfam PF00005 ABC transporter 22 164 1.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28985 1dfa7e32f4db057ae55e78514f2b8b4e 250 SUPERFAMILY SSF52540 3 235 2.38E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 44 1.9E-10 T 29-03-2018 A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 Pfam PF00294 pfkB family carbohydrate kinase 58 348 9.2E-64 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 SUPERFAMILY SSF53613 59 355 3.27E-70 T 29-03-2018 IPR029056 Ribokinase-like A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 PRINTS PR00990 Ribokinase signature 230 245 4.1E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 PRINTS PR00990 Ribokinase signature 274 285 4.1E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 PRINTS PR00990 Ribokinase signature 87 106 4.1E-5 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 92 116 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 Gene3D G3DSA:1.10.10.10 1 59 3.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 Gene3D G3DSA:3.40.1190.20 60 366 1.4E-65 T 29-03-2018 IPR029056 Ribokinase-like A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 SUPERFAMILY SSF46785 3 49 1.36E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 SMART SM00419 9 55 0.0016 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS02205 ef0904c0a099ed2a6cb40551783bd36d 366 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 303 316 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A616_RS31485 e47369787a61f7e62655dbb6cff87368 124 Gene3D G3DSA:1.10.4040.10 73 121 2.9E-18 T 29-03-2018 A616_RS31485 e47369787a61f7e62655dbb6cff87368 124 Pfam PF03965 Penicillinase repressor 7 120 5.6E-38 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A616_RS31485 e47369787a61f7e62655dbb6cff87368 124 PIRSF PIRSF019455 2 124 2.4E-40 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A616_RS31485 e47369787a61f7e62655dbb6cff87368 124 SUPERFAMILY SSF46785 5 123 5.19E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31485 e47369787a61f7e62655dbb6cff87368 124 Gene3D G3DSA:1.10.10.10 8 70 2.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27910 eb2df1c3251f8a2fcef7755f46902894 473 Gene3D G3DSA:2.60.40.1610 86 231 8.4E-43 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 A616_RS27910 eb2df1c3251f8a2fcef7755f46902894 473 Pfam PF06742 Protein of unknown function (DUF1214) 346 453 2.4E-31 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 A616_RS27910 eb2df1c3251f8a2fcef7755f46902894 473 Pfam PF06863 Protein of unknown function (DUF1254) 87 218 1.1E-43 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 A616_RS27910 eb2df1c3251f8a2fcef7755f46902894 473 Gene3D G3DSA:2.60.120.600 299 471 3.2E-44 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 A616_RS27910 eb2df1c3251f8a2fcef7755f46902894 473 SUPERFAMILY SSF160935 51 467 2.22E-108 T 29-03-2018 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 PIRSF PIRSF006641 1 366 1.1E-161 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 Gene3D G3DSA:3.10.20.30 266 365 2.4E-46 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 Gene3D G3DSA:3.40.50.300 2 80 4.2E-8 T 29-03-2018 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.309 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 Gene3D G3DSA:1.10.150.300 110 200 1.4E-30 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 SUPERFAMILY SSF52540 5 304 5.6E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 SUPERFAMILY SSF81271 282 363 3.49E-35 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 Pfam PF01926 50S ribosome-binding GTPase 5 115 5.8E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 5.0E-158 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.0E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS32190 b92b27000c02def1d3d7ee5e99a5b146 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 1.1E-38 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 A616_RS19105 c8b8bfdeae1da8971fd8427debbb04b3 296 Pfam PF13527 Acetyltransferase (GNAT) domain 20 131 4.4E-15 T 29-03-2018 A616_RS19105 c8b8bfdeae1da8971fd8427debbb04b3 296 Gene3D G3DSA:3.40.630.30 3 170 4.1E-19 T 29-03-2018 A616_RS19105 c8b8bfdeae1da8971fd8427debbb04b3 296 SUPERFAMILY SSF55729 16 255 2.83E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25815 3769816d8f084394c22387e9d624f863 585 Gene3D G3DSA:3.30.450.20 35 208 4.0E-38 T 29-03-2018 A616_RS25815 3769816d8f084394c22387e9d624f863 585 SMART SM01049 46 144 5.8E-14 T 29-03-2018 IPR033480 Single Cache domain 2 A616_RS25815 3769816d8f084394c22387e9d624f863 585 Pfam PF17200 Single Cache domain 2 45 205 2.7E-50 T 29-03-2018 IPR033480 Single Cache domain 2 A616_RS25815 3769816d8f084394c22387e9d624f863 585 SUPERFAMILY SSF58104 252 282 3.01E-72 T 29-03-2018 A616_RS25815 3769816d8f084394c22387e9d624f863 585 SUPERFAMILY SSF58104 315 584 3.01E-72 T 29-03-2018 A616_RS25815 3769816d8f084394c22387e9d624f863 585 Gene3D G3DSA:1.10.287.950 535 585 6.0E-8 T 29-03-2018 A616_RS25815 3769816d8f084394c22387e9d624f863 585 Gene3D G3DSA:1.10.287.950 336 534 1.3E-51 T 29-03-2018 A616_RS25815 3769816d8f084394c22387e9d624f863 585 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 357 536 5.3E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS25815 3769816d8f084394c22387e9d624f863 585 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 330 359 2.0E-25 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS25815 3769816d8f084394c22387e9d624f863 585 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 484 513 2.0E-25 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS25815 3769816d8f084394c22387e9d624f863 585 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 436 465 2.0E-25 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS25815 3769816d8f084394c22387e9d624f863 585 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 407 434 2.0E-25 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS25815 3769816d8f084394c22387e9d624f863 585 SMART SM00304 227 280 9.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25815 3769816d8f084394c22387e9d624f863 585 SMART SM00304 301 347 84.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25815 3769816d8f084394c22387e9d624f863 585 Gene3D G3DSA:1.10.287.950 229 335 2.5E-7 T 29-03-2018 A616_RS25815 3769816d8f084394c22387e9d624f863 585 SMART SM00283 309 584 5.0E-95 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS25815 3769816d8f084394c22387e9d624f863 585 Pfam PF00672 HAMP domain 229 277 1.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 Pfam PF14568 SMI1-KNR4 cell-wall 170 304 1.2E-28 T 29-03-2018 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 SMART SM00028 69 102 6.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 SMART SM00028 35 68 10.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 Gene3D G3DSA:1.10.150.200 15 45 0.0043 T 29-03-2018 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 Gene3D G3DSA:3.40.1580.10 149 316 2.8E-24 T 29-03-2018 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 Gene3D G3DSA:1.25.40.10 79 123 3.6E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 Gene3D G3DSA:1.25.40.10 46 78 5.6E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 SUPERFAMILY SSF160631 157 310 4.32E-29 T 29-03-2018 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 Pfam PF13432 Tetratricopeptide repeat 41 96 9.6E-8 T 29-03-2018 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 SUPERFAMILY SSF48452 23 118 1.02E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31985 2d23d725df1c80381cb1a31d238c32e5 459 SMART SM00860 167 306 3.3E-12 T 29-03-2018 IPR018958 Knr4/Smi1-like domain A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 Gene3D G3DSA:1.20.58.100 427 532 1.2E-27 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 3.1E-274 T 29-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 1.2E-41 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 SUPERFAMILY SSF46977 443 579 9.94E-45 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.2E-9 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 3.2E-9 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 SUPERFAMILY SSF51905 6 247 3.02E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 SUPERFAMILY SSF51905 357 424 3.02E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 Gene3D G3DSA:3.50.50.60 5 417 8.7E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 1.4E-6 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.4E-6 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 Gene3D G3DSA:4.10.80.40 533 583 5.8E-9 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 Pfam PF00890 FAD binding domain 6 392 2.1E-88 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 SUPERFAMILY SSF56425 231 353 7.78E-31 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 PIRSF PIRSF000171 342 574 1.9E-15 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 PIRSF PIRSF000171 2 240 3.2E-18 T 29-03-2018 A616_RS09785 4df82c3dc20b52b2938b6cb8e3de5b52 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 Gene3D G3DSA:3.40.630.10 4 258 1.2E-47 T 29-03-2018 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 Pfam PF07687 Peptidase dimerisation domain 175 267 5.8E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 Pfam PF01546 Peptidase family M20/M25/M40 71 371 1.9E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 PIRSF PIRSF005962 3 376 1.7E-83 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 SUPERFAMILY SSF55031 176 281 2.69E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 SUPERFAMILY SSF53187 287 372 1.14E-57 T 29-03-2018 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 SUPERFAMILY SSF53187 6 188 1.14E-57 T 29-03-2018 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 361 3.4E-74 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS04815 6caf60a9858462bd2f3ff844ebc24382 377 Gene3D G3DSA:3.40.630.10 259 377 1.7E-15 T 29-03-2018 A616_RS14685 723110d36138ec54ea9defae5dd79f16 254 Gene3D G3DSA:3.20.20.370 3 250 1.0E-107 T 29-03-2018 A616_RS14685 723110d36138ec54ea9defae5dd79f16 254 Pfam PF03746 LamB/YcsF family 4 241 5.0E-105 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A616_RS14685 723110d36138ec54ea9defae5dd79f16 254 SUPERFAMILY SSF88713 3 249 8.89E-102 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS14685 723110d36138ec54ea9defae5dd79f16 254 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 46.528 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 Gene3D G3DSA:3.40.190.10 1 92 3.7E-28 T 29-03-2018 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 SUPERFAMILY SSF53850 4 188 3.98E-49 T 29-03-2018 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 Gene3D G3DSA:3.30.70.260 192 287 1.3E-24 T 29-03-2018 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 SUPERFAMILY SSF55021 192 280 2.68E-23 T 29-03-2018 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 PIRSF PIRSF001500 1 282 3.3E-69 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 Pfam PF01842 ACT domain 200 254 1.3E-6 T 29-03-2018 IPR002912 ACT domain A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 Pfam PF00800 Prephenate dehydratase 6 188 3.7E-56 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 Gene3D G3DSA:3.40.190.10 93 176 7.5E-23 T 29-03-2018 A616_RS10615 2d654dae3a2553b74e734156d42f65cf 287 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 228 235 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 SUPERFAMILY SSF52788 1 148 4.19E-49 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 SMART SM00226 2 147 3.1E-54 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 1.9E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 1.9E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.9E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 121 136 1.9E-19 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 1.2E-42 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS05020 8e50cda8713610150d9a7fe6b11a3635 156 Gene3D G3DSA:3.40.50.2300 1 156 1.1E-51 T 29-03-2018 A616_RS11950 8c680122a3255598d0fa648111c6e01f 299 Pfam PF00149 Calcineurin-like phosphoesterase 49 212 3.6E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS11950 8c680122a3255598d0fa648111c6e01f 299 SUPERFAMILY SSF56300 50 278 4.71E-29 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS11950 8c680122a3255598d0fa648111c6e01f 299 Gene3D G3DSA:3.60.21.10 45 271 1.5E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 Gene3D G3DSA:3.30.200.20 1 111 6.3E-36 T 29-03-2018 A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 SUPERFAMILY SSF56112 2 396 1.3E-92 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 Pfam PF01636 Phosphotransferase enzyme family 31 264 2.2E-12 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 PIRSF PIRSF031134 1 400 1.4E-160 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 409 200.514 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 Gene3D G3DSA:3.90.1200.10 112 369 1.5E-15 T 29-03-2018 A616_RS26890 d514ce362ea8f1d10dc404255c9e74ca 409 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 31 398 1.1E-141 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 Gene3D G3DSA:3.40.50.620 3 189 1.3E-41 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 SUPERFAMILY SSF52402 3 190 9.07E-46 T 29-03-2018 A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 SMART SM00893 5 193 9.3E-31 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 SUPERFAMILY SSF52467 196 316 5.77E-49 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 Pfam PF01012 Electron transfer flavoprotein domain 5 174 1.7E-37 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 Gene3D G3DSA:3.40.50.1220 192 320 1.5E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 197 279 2.3E-35 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 260 286 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 A616_RS15345 25fdc9cc7c9b8896a88fc932e5b81bb0 322 PIRSF PIRSF000089 1 320 1.5E-110 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 9.8E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 9.8E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 9.8E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 9.8E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 9.8E-45 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 189 7.8E-62 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 SUPERFAMILY SSF55347 184 485 9.48E-106 T 29-03-2018 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 PIRSF PIRSF000110 1 488 1.5E-181 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 484 3.7E-105 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 Gene3D G3DSA:3.30.360.10 191 487 2.9E-117 T 29-03-2018 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 Gene3D G3DSA:3.40.50.720 1 190 6.6E-67 T 29-03-2018 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 485 2.1E-176 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 SUPERFAMILY SSF51735 2 185 3.54E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20940 d503cda42c5d9101a3049ab95bfb0a5d 499 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 3 486 79.781 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 A616_RS05265 1a6e42f3d8732a44283750b99282e922 381 SMART SM00862 18 92 4.3E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05265 1a6e42f3d8732a44283750b99282e922 381 Gene3D G3DSA:1.25.40.10 119 375 7.5E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS05265 1a6e42f3d8732a44283750b99282e922 381 SUPERFAMILY SSF48452 219 323 4.64E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS05265 1a6e42f3d8732a44283750b99282e922 381 Gene3D G3DSA:1.10.10.10 5 99 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05265 1a6e42f3d8732a44283750b99282e922 381 SUPERFAMILY SSF46894 8 93 5.1E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS05265 1a6e42f3d8732a44283750b99282e922 381 Pfam PF00486 Transcriptional regulatory protein, C terminal 18 92 1.6E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 Gene3D G3DSA:1.10.10.10 1 78 4.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 SUPERFAMILY SSF46785 6 77 3.16E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 SMART SM00346 5 95 3.4E-22 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 Pfam PF01614 Bacterial transcriptional regulator 131 247 7.9E-27 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 Gene3D G3DSA:3.30.450.40 79 253 4.2E-45 T 29-03-2018 IPR029016 GAF domain-like A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 SUPERFAMILY SSF55781 71 250 1.24E-43 T 29-03-2018 IPR029016 GAF domain-like A616_RS03670 e852a8bcf092481324ceafcdc861afda 253 Pfam PF09339 IclR helix-turn-helix domain 7 57 6.6E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS29570 7757f9dc69db582dd083448929c90891 300 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 142 4.2E-22 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS29570 7757f9dc69db582dd083448929c90891 300 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 4 193 2.1E-59 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 A616_RS29570 7757f9dc69db582dd083448929c90891 300 Pfam PF00700 Bacterial flagellin C-terminal helical region 218 298 4.7E-7 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS29570 7757f9dc69db582dd083448929c90891 300 Gene3D G3DSA:1.10.8.290 10 41 0.2 T 29-03-2018 IPR023204 SP1917 domain A616_RS29570 7757f9dc69db582dd083448929c90891 300 SUPERFAMILY SSF64518 1 300 4.71E-67 T 29-03-2018 A616_RS29570 7757f9dc69db582dd083448929c90891 300 Gene3D G3DSA:1.20.1330.10 42 274 5.2E-37 T 29-03-2018 A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 18 179 1.3E-48 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 85 97 9.5E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 34 50 9.5E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 158 9.5E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 SUPERFAMILY SSF51306 33 183 1.13E-48 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 Pfam PF00717 Peptidase S24-like 41 109 3.9E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 ProSitePatterns PS00761 Signal peptidases I signature 3. 144 157 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A616_RS20480 6b866fe76269205a8e32cd91e5a64ca6 186 Gene3D G3DSA:2.10.109.10 30 184 1.1E-46 T 29-03-2018 A616_RS29425 b5b92c6b2d256ce089308109e46e6b7e 264 SMART SM00079 42 263 0.0051 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS29425 b5b92c6b2d256ce089308109e46e6b7e 264 SMART SM00062 42 264 2.4E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS29425 b5b92c6b2d256ce089308109e46e6b7e 264 SUPERFAMILY SSF53850 11 263 3.19E-66 T 29-03-2018 A616_RS29425 b5b92c6b2d256ce089308109e46e6b7e 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 263 9.9E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS29425 b5b92c6b2d256ce089308109e46e6b7e 264 Gene3D G3DSA:3.40.190.10 35 186 3.9E-41 T 29-03-2018 A616_RS29425 b5b92c6b2d256ce089308109e46e6b7e 264 Gene3D G3DSA:3.40.190.10 187 264 3.7E-15 T 29-03-2018 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 SUPERFAMILY SSF48179 160 264 4.25E-20 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 SUPERFAMILY SSF51735 3 156 4.97E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 PIRSF PIRSF000193 1 266 4.0E-64 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 Gene3D G3DSA:3.40.50.720 1 158 5.6E-23 T 29-03-2018 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 221 243 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 260 7.0E-17 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 267 17.841 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 98 6.6E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A616_RS11250 4396e70f8dc132cf4e1d393d72f3767f 277 Gene3D G3DSA:1.10.3730.10 168 272 1.0E-18 T 29-03-2018 A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 Gene3D G3DSA:1.10.1740.10 1 103 2.1E-18 T 29-03-2018 A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 SUPERFAMILY SSF88946 6 100 1.0E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 Pfam PF04542 Sigma-70 region 2 25 91 1.5E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 Gene3D G3DSA:1.10.10.10 104 187 4.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 SUPERFAMILY SSF88659 111 178 4.67E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 176 1.8E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09615 4c1bd69af8ca94031a119081ecb19014 195 Pfam PF08281 Sigma-70, region 4 123 174 1.7E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 112 124 2.9E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 151 166 2.9E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 86 101 2.9E-14 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 Gene3D G3DSA:2.40.100.10 51 231 1.4E-56 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 SUPERFAMILY SSF50891 72 228 1.14E-51 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 74 226 4.3E-43 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS18910 bf4151c99b09f6de5e6492e098ae8f82 231 PIRSF PIRSF001467 59 228 6.5E-45 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A616_RS04525 3500ccda7e1d2d2925531d12c5838d21 623 Pfam PF02687 FtsX-like permease family 84 177 1.3E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS04525 3500ccda7e1d2d2925531d12c5838d21 623 PIRSF PIRSF018968 1 378 1.3E-36 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A616_RS04525 3500ccda7e1d2d2925531d12c5838d21 623 PIRSF PIRSF018968 408 621 3.9E-20 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A616_RS14520 d028005ac6126c9b9f44161cb2a20feb 453 Gene3D G3DSA:3.20.20.70 144 449 2.8E-145 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS14520 d028005ac6126c9b9f44161cb2a20feb 453 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 5.1E-197 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS14520 d028005ac6126c9b9f44161cb2a20feb 453 Gene3D G3DSA:2.30.170.30 1 53 3.6E-20 T 29-03-2018 A616_RS14520 d028005ac6126c9b9f44161cb2a20feb 453 Gene3D G3DSA:1.10.220.70 56 140 2.2E-30 T 29-03-2018 A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 Gene3D G3DSA:1.10.10.10 112 182 4.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 Gene3D G3DSA:1.10.1740.10 2 111 2.1E-25 T 29-03-2018 A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 SUPERFAMILY SSF88659 110 172 3.36E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 Pfam PF08281 Sigma-70, region 4 116 165 1.2E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 170 1.5E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 Pfam PF04542 Sigma-70 region 2 26 92 5.6E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23930 2f9a9c4cd9d1dc8bce53836d4656c73e 200 SUPERFAMILY SSF88946 5 102 3.92E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS25875 c1789f2ea6b6dc963d79fb57b00458ef 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 244 331 2.3E-24 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS25875 c1789f2ea6b6dc963d79fb57b00458ef 331 Gene3D G3DSA:3.40.47.10 165 331 7.1E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS25875 c1789f2ea6b6dc963d79fb57b00458ef 331 SUPERFAMILY SSF53901 4 330 1.36E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS25875 c1789f2ea6b6dc963d79fb57b00458ef 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 188 1.3E-23 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A616_RS25875 c1789f2ea6b6dc963d79fb57b00458ef 331 Gene3D G3DSA:3.40.47.10 1 164 6.8E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 PRINTS PR00297 10kDa chaperonin signature 59 71 9.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 PRINTS PR00297 10kDa chaperonin signature 2 17 9.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 PRINTS PR00297 10kDa chaperonin signature 80 93 9.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 PRINTS PR00297 10kDa chaperonin signature 24 45 9.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 Gene3D G3DSA:2.30.33.40 1 94 1.3E-40 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 SMART SM00883 1 93 3.9E-55 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 26.918 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 3.9E-37 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A616_RS03020 e9d3b1ec7fa01681510d076b6d51cd1b 94 SUPERFAMILY SSF50129 2 93 7.42E-35 T 29-03-2018 IPR011032 GroES-like A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 SUPERFAMILY SSF51338 4 61 1.11E-34 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 SUPERFAMILY SSF51338 358 432 1.11E-34 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 Gene3D G3DSA:2.30.40.10 345 418 0.015 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 Gene3D G3DSA:3.20.20.140 74 344 1.3E-61 T 29-03-2018 A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 Gene3D G3DSA:2.30.40.10 1 73 1.0E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 Pfam PF01979 Amidohydrolase family 58 406 2.9E-74 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 SUPERFAMILY SSF51556 61 351 6.45E-96 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS13985 3a13bd358a0535554d76cffa2c5acae3 434 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 433 46.13 T 29-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 Gene3D G3DSA:3.20.20.70 1 339 3.0E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 Pfam PF13353 4Fe-4S single cluster domain 22 127 2.6E-10 T 29-03-2018 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 Pfam PF04055 Radical SAM superfamily 18 182 1.2E-32 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 SMART SM00729 14 222 3.3E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 339 1.2E-118 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 339 40.94 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 Pfam PF06463 Molybdenum Cofactor Synthesis C 190 315 1.8E-37 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 A616_RS09425 04108fdbe710c8936f08b8e94a61420e 339 SUPERFAMILY SSF102114 6 306 5.49E-80 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 SUPERFAMILY SSF48371 301 377 4.43E-12 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 Pfam PF13484 4Fe-4S double cluster binding domain 192 254 1.5E-16 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 SMART SM00567 E-Z type HEAT repeats 302 331 82.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 SMART SM00567 E-Z type HEAT repeats 334 363 1.0E-5 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 Pfam PF13646 HEAT repeats 304 372 2.0E-11 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 Pfam PF08331 Domain of unknown function (DUF1730) 61 139 1.6E-17 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 14 346 2.2E-127 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 Gene3D G3DSA:3.30.70.20 78 198 2.3E-4 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 Gene3D G3DSA:1.25.40.70 280 381 2.9E-10 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 SUPERFAMILY SSF54862 168 281 3.72E-15 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 Gene3D G3DSA:3.30.70.20 199 255 6.5E-8 T 29-03-2018 A616_RS06115 422d2feee78fd187888201a0dea7d287 383 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 192 203 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A616_RS12820 4c43225bede84bc091672a2c9b6c2c1e 90 PIRSF PIRSF010606 2 90 1.8E-36 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB A616_RS12820 4c43225bede84bc091672a2c9b6c2c1e 90 Pfam PF12652 CotJB protein 14 89 2.4E-28 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain A616_RS15045 daa33824a087a8908311e3cb3e64dc5a 216 Gene3D G3DSA:1.10.3720.10 2 216 5.0E-34 T 29-03-2018 A616_RS15045 daa33824a087a8908311e3cb3e64dc5a 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 214 6.6E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15045 daa33824a087a8908311e3cb3e64dc5a 216 SUPERFAMILY SSF161098 7 200 1.7E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 SUPERFAMILY SSF88946 12 87 3.73E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 Gene3D G3DSA:1.10.1740.10 4 74 2.1E-20 T 29-03-2018 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 SUPERFAMILY SSF88659 97 165 4.49E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 Pfam PF08281 Sigma-70, region 4 109 158 1.7E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 Pfam PF04542 Sigma-70 region 2 13 77 4.3E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 164 4.9E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31935 441a8fc3ee7eda87e4d53c2aab86066b 179 Gene3D G3DSA:1.10.10.10 75 167 3.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11515 ae60a232e68d3dee902ba8a90a8aae5a 327 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 5 309 2.1E-80 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 A616_RS11515 ae60a232e68d3dee902ba8a90a8aae5a 327 Pfam PF02690 Na+/Pi-cotransporter 15 149 2.3E-42 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A616_RS11515 ae60a232e68d3dee902ba8a90a8aae5a 327 Pfam PF02690 Na+/Pi-cotransporter 151 255 2.8E-16 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A616_RS23055 f7ea3c508b58d6c2d2cc9849283f692d 93 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 89 6.6E-18 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 A616_RS23055 f7ea3c508b58d6c2d2cc9849283f692d 93 PIRSF PIRSF020408 2 92 1.2E-33 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 147 168 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 10 188 1.1E-65 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 Pfam PF01634 ATP phosphoribosyltransferase 59 205 3.2E-52 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 SUPERFAMILY SSF53850 7 207 1.17E-69 T 29-03-2018 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 Gene3D G3DSA:3.40.190.10 118 180 9.2E-28 T 29-03-2018 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 Gene3D G3DSA:3.40.190.10 4 117 4.4E-40 T 29-03-2018 A616_RS29230 2a0f146485f439951f5e964de12dccf8 215 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 9 212 56.547 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A616_RS25590 3a648501f058b23b59cc8ceca2ff7973 296 SUPERFAMILY SSF56601 2 149 7.52E-55 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25590 3a648501f058b23b59cc8ceca2ff7973 296 SUPERFAMILY SSF56601 183 291 7.52E-55 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25590 3a648501f058b23b59cc8ceca2ff7973 296 Gene3D G3DSA:3.40.710.10 2 296 4.6E-44 T 29-03-2018 A616_RS25590 3a648501f058b23b59cc8ceca2ff7973 296 Pfam PF13354 Beta-lactamase enzyme family 25 264 6.8E-59 T 29-03-2018 A616_RS06805 6909f7f2f7270c6f5daddc68698bcbd8 435 Gene3D G3DSA:1.20.1250.20 229 428 3.3E-27 T 29-03-2018 A616_RS06805 6909f7f2f7270c6f5daddc68698bcbd8 435 Gene3D G3DSA:1.20.1250.20 8 214 6.3E-27 T 29-03-2018 A616_RS06805 6909f7f2f7270c6f5daddc68698bcbd8 435 Pfam PF07690 Major Facilitator Superfamily 34 379 2.3E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS06805 6909f7f2f7270c6f5daddc68698bcbd8 435 SUPERFAMILY SSF103473 16 427 2.49E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS01875 171e47d646059bf7b31010b748e105c8 259 Pfam PF04199 Putative cyclase 9 183 5.7E-40 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A616_RS01875 171e47d646059bf7b31010b748e105c8 259 SUPERFAMILY SSF102198 5 255 7.46E-54 T 29-03-2018 A616_RS01875 171e47d646059bf7b31010b748e105c8 259 Gene3D G3DSA:3.50.30.50 4 258 8.4E-61 T 29-03-2018 A616_RS21600 1df9ad6d36bcf5a1ab45d28b1ceb5460 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 4.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS21600 1df9ad6d36bcf5a1ab45d28b1ceb5460 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 4.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS21600 1df9ad6d36bcf5a1ab45d28b1ceb5460 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 4.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS21600 1df9ad6d36bcf5a1ab45d28b1ceb5460 265 Gene3D G3DSA:3.40.50.1820 2 265 1.6E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS21600 1df9ad6d36bcf5a1ab45d28b1ceb5460 265 SUPERFAMILY SSF53474 10 260 1.04E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS21600 1df9ad6d36bcf5a1ab45d28b1ceb5460 265 Pfam PF12146 Serine aminopeptidase, S33 11 247 2.2E-68 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 Pfam PF00664 ABC transporter transmembrane region 20 292 1.2E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 Gene3D G3DSA:3.40.50.300 332 587 1.1E-80 T 29-03-2018 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 Gene3D G3DSA:1.20.1560.10 1 330 2.3E-71 T 29-03-2018 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 Pfam PF00005 ABC transporter 363 512 1.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 SUPERFAMILY SSF90123 4 321 6.28E-81 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS05835 300770ec77118e8186af0a332dd6510b 593 SUPERFAMILY SSF52540 340 582 2.95E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05835 300770ec77118e8186af0a332dd6510b 593 SMART SM00382 372 558 9.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 PIRSF PIRSF029271 1 294 3.0E-153 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 Gene3D G3DSA:3.20.20.70 18 271 1.7E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 SUPERFAMILY SSF51366 18 268 1.13E-66 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 Pfam PF01680 SOR/SNZ family 7 212 3.3E-107 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 53.289 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 8.1E-156 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS00220 d76fe4c7179b48f4b5f7c3ea41421b14 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 Pfam PF08281 Sigma-70, region 4 118 171 3.8E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 Gene3D G3DSA:1.10.1740.10 1 92 6.3E-27 T 29-03-2018 A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 Gene3D G3DSA:1.10.10.10 93 178 4.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 SUPERFAMILY SSF88659 107 175 9.16E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 SUPERFAMILY SSF88946 3 105 5.34E-31 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 Pfam PF04542 Sigma-70 region 2 22 88 8.0E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22350 225b7b4c0f9d01f633af9f59e465b82e 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 174 3.8E-34 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31000 9abceff5b53685834d7511518c703abb 108 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 97 1.9E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A616_RS31000 9abceff5b53685834d7511518c703abb 108 Gene3D G3DSA:1.20.58.80 2 99 2.2E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A616_RS31000 9abceff5b53685834d7511518c703abb 108 PIRSF PIRSF000699 2 105 7.5E-36 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A616_RS31000 9abceff5b53685834d7511518c703abb 108 SUPERFAMILY SSF46973 3 98 1.15E-33 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 A616_RS18475 8d037b5ca4645e81a086c06da404cc54 256 Gene3D G3DSA:3.90.1530.10 7 92 2.9E-8 T 29-03-2018 A616_RS18475 8d037b5ca4645e81a086c06da404cc54 256 SUPERFAMILY SSF110849 7 223 2.49E-20 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS18475 8d037b5ca4645e81a086c06da404cc54 256 SMART SM00470 9 92 0.0065 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS18475 8d037b5ca4645e81a086c06da404cc54 256 PIRSF PIRSF032543 1 256 5.5E-52 T 29-03-2018 IPR016999 Uncharacterised conserved protein UCP032543, ParB-like nuclease A616_RS18475 8d037b5ca4645e81a086c06da404cc54 256 Pfam PF02195 ParB-like nuclease domain 28 82 8.1E-7 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 Gene3D G3DSA:3.40.190.10 171 268 1.2E-16 T 29-03-2018 A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 Gene3D G3DSA:3.40.190.10 6 170 7.5E-40 T 29-03-2018 A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 SUPERFAMILY SSF53850 2 268 3.05E-68 T 29-03-2018 A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 268 7.4E-60 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 SMART SM00062 45 267 1.2E-67 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS20730 8fd200066839f03b6b3e3ae5ed499749 268 SMART SM00079 45 268 2.8E-5 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 Gene3D G3DSA:1.10.10.10 2 173 1.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 SMART SM00347 55 156 6.3E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 SUPERFAMILY SSF46785 30 169 1.61E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 Pfam PF01047 MarR family 62 120 1.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 95 129 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 146 166 4.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 4.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 112 4.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25685 39c45e2f5ff3205f53de5618458b9ad4 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 132 4.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 2.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 2.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 2.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 Pfam PF00106 short chain dehydrogenase 23 211 1.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 Gene3D G3DSA:3.40.50.720 7 276 1.5E-57 T 29-03-2018 A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 SUPERFAMILY SSF51735 21 271 1.35E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 8.0E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 8.0E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 8.0E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 8.0E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22785 85c169bf1bea7bb4e17833ecf7fcdaad 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 8.0E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS04850 93c19dc670a8fdc883c282b41c13b1d8 108 Pfam PF08921 Domain of unknown function (DUF1904) 1 107 4.6E-31 T 29-03-2018 IPR015017 Protein of unknown function DUF1904 A616_RS04850 93c19dc670a8fdc883c282b41c13b1d8 108 SUPERFAMILY SSF55331 1 108 1.53E-31 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily A616_RS04850 93c19dc670a8fdc883c282b41c13b1d8 108 Gene3D G3DSA:3.30.429.10 2 107 9.7E-34 T 29-03-2018 A616_RS29630 050039a4a654f03f7142598d349394a1 858 Gene3D G3DSA:2.60.120.380 553 675 3.2E-17 T 29-03-2018 A616_RS29630 050039a4a654f03f7142598d349394a1 858 Gene3D G3DSA:2.60.120.380 429 552 1.8E-15 T 29-03-2018 A616_RS29630 050039a4a654f03f7142598d349394a1 858 SUPERFAMILY SSF89260 560 660 1.44E-8 T 29-03-2018 A616_RS29630 050039a4a654f03f7142598d349394a1 858 Gene3D G3DSA:3.40.50.200 11 314 6.6E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS29630 050039a4a654f03f7142598d349394a1 858 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 101 111 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A616_RS29630 050039a4a654f03f7142598d349394a1 858 Pfam PF00395 S-layer homology domain 682 723 1.9E-11 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29630 050039a4a654f03f7142598d349394a1 858 Pfam PF00395 S-layer homology domain 746 789 1.2E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29630 050039a4a654f03f7142598d349394a1 858 Pfam PF00395 S-layer homology domain 808 848 1.3E-8 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29630 050039a4a654f03f7142598d349394a1 858 PRINTS PR00723 Subtilisin serine protease family (S8) signature 251 267 7.7E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS29630 050039a4a654f03f7142598d349394a1 858 PRINTS PR00723 Subtilisin serine protease family (S8) signature 59 78 7.7E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS29630 050039a4a654f03f7142598d349394a1 858 PRINTS PR00723 Subtilisin serine protease family (S8) signature 97 110 7.7E-18 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS29630 050039a4a654f03f7142598d349394a1 858 SUPERFAMILY SSF89260 433 549 2.22E-12 T 29-03-2018 A616_RS29630 050039a4a654f03f7142598d349394a1 858 Pfam PF00082 Subtilase family 60 302 1.0E-46 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS29630 050039a4a654f03f7142598d349394a1 858 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 252 262 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A616_RS29630 050039a4a654f03f7142598d349394a1 858 SUPERFAMILY SSF52743 41 314 5.5E-88 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS29630 050039a4a654f03f7142598d349394a1 858 Gene3D G3DSA:2.60.120.380 315 428 1.9E-10 T 29-03-2018 A616_RS04085 ab3ebb97559982b0b9dc33b0c0d84cfb 401 Pfam PF00589 Phage integrase family 191 379 2.0E-34 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS04085 ab3ebb97559982b0b9dc33b0c0d84cfb 401 Gene3D G3DSA:1.10.150.130 68 192 3.6E-24 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS04085 ab3ebb97559982b0b9dc33b0c0d84cfb 401 SUPERFAMILY SSF56349 73 388 6.77E-77 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS04085 ab3ebb97559982b0b9dc33b0c0d84cfb 401 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 75 132 2.0E-12 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS04085 ab3ebb97559982b0b9dc33b0c0d84cfb 401 Gene3D G3DSA:1.10.443.10 193 388 7.9E-47 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 SUPERFAMILY SSF53218 10 167 3.93E-42 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 2.1E-34 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 Pfam PF00994 Probable molybdopterin binding domain 18 161 4.0E-32 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 PIRSF PIRSF006443 1 168 1.2E-64 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 SMART SM00852 17 162 7.7E-31 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 Gene3D G3DSA:3.40.980.10 1 168 5.5E-32 T 29-03-2018 IPR001453 MoaB/Mog domain A616_RS09510 e92a27c46ed61b8ed4a6c810d5cf6296 168 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A616_RS09640 34a9f9534018785cf42ec8d003be2955 449 Pfam PF00534 Glycosyl transferases group 1 251 413 5.3E-9 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS09640 34a9f9534018785cf42ec8d003be2955 449 Gene3D G3DSA:3.40.50.2000 2 249 2.8E-13 T 29-03-2018 A616_RS09640 34a9f9534018785cf42ec8d003be2955 449 Gene3D G3DSA:3.40.50.2000 250 421 2.9E-13 T 29-03-2018 A616_RS09640 34a9f9534018785cf42ec8d003be2955 449 Pfam PF13579 Glycosyl transferase 4-like domain 18 235 4.5E-10 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS09640 34a9f9534018785cf42ec8d003be2955 449 SUPERFAMILY SSF53756 114 446 3.18E-34 T 29-03-2018 A616_RS09640 34a9f9534018785cf42ec8d003be2955 449 SUPERFAMILY SSF53756 7 74 3.18E-34 T 29-03-2018 A616_RS02575 a5eddae5a9780eb51027add0acd8ad22 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 203 222 3.6E-7 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A616_RS02575 a5eddae5a9780eb51027add0acd8ad22 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 183 202 3.6E-7 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A616_RS02575 a5eddae5a9780eb51027add0acd8ad22 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 146 170 3.6E-7 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A616_RS02575 a5eddae5a9780eb51027add0acd8ad22 269 Pfam PF01061 ABC-2 type transporter 30 223 4.7E-15 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A616_RS02575 a5eddae5a9780eb51027add0acd8ad22 269 PIRSF PIRSF006648 11 261 1.3E-24 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A616_RS21855 90d98213c666d3998d49249d3d14bdd7 333 Pfam PF01497 Periplasmic binding protein 116 309 9.7E-23 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS21855 90d98213c666d3998d49249d3d14bdd7 333 SUPERFAMILY SSF53807 58 315 1.26E-46 T 29-03-2018 A616_RS21855 90d98213c666d3998d49249d3d14bdd7 333 Gene3D G3DSA:3.40.50.1980 174 331 1.4E-28 T 29-03-2018 A616_RS21855 90d98213c666d3998d49249d3d14bdd7 333 Gene3D G3DSA:3.40.50.1980 43 173 1.8E-16 T 29-03-2018 A616_RS14700 d788b5ac741fcfba164cd7f04b5f4b03 501 PIRSF PIRSF005690 7 492 5.3E-132 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS14700 d788b5ac741fcfba164cd7f04b5f4b03 501 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 20 477 4.2E-147 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS26320 5660857737bd532c6fc75895d36269fe 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 178 1.7E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26320 5660857737bd532c6fc75895d36269fe 194 SUPERFAMILY SSF88659 118 178 2.99E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26320 5660857737bd532c6fc75895d36269fe 194 SUPERFAMILY SSF88946 2 94 3.22E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26320 5660857737bd532c6fc75895d36269fe 194 Gene3D G3DSA:1.10.10.10 106 183 3.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26320 5660857737bd532c6fc75895d36269fe 194 Pfam PF04542 Sigma-70 region 2 26 89 2.8E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26320 5660857737bd532c6fc75895d36269fe 194 Pfam PF08281 Sigma-70, region 4 124 174 4.6E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS26320 5660857737bd532c6fc75895d36269fe 194 Gene3D G3DSA:1.10.1740.10 8 94 6.5E-21 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 SMART SM00304 300 352 5.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 SMART SM00283 381 656 5.5E-73 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Gene3D G3DSA:1.10.287.950 319 414 5.9E-8 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Pfam PF00672 HAMP domain 301 348 3.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Gene3D G3DSA:1.10.287.950 415 607 2.6E-50 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Gene3D G3DSA:1.10.287.950 608 657 1.6E-5 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Pfam PF02743 Cache domain 41 262 3.7E-27 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 SUPERFAMILY SSF58104 320 354 1.7E-69 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 SUPERFAMILY SSF58104 387 655 1.7E-69 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 SUPERFAMILY SSF103190 84 182 1.49E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 425 609 3.0E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Gene3D G3DSA:3.30.450.20 27 154 3.4E-8 T 29-03-2018 A616_RS30850 3bb2f0a37b5aeca927986bb5a44ed2e6 657 Gene3D G3DSA:3.30.450.20 155 269 8.2E-24 T 29-03-2018 A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 Gene3D G3DSA:1.10.10.10 129 237 7.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 SUPERFAMILY SSF46894 135 233 5.67E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 SMART SM00862 156 232 1.2E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 232 3.3E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 SUPERFAMILY SSF52172 3 129 2.56E-36 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 SMART SM00448 4 115 9.6E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 Gene3D G3DSA:3.40.50.2300 3 128 1.9E-32 T 29-03-2018 A616_RS25825 7b133100fe905298cdaf0e8f9b17df6a 241 Pfam PF00072 Response regulator receiver domain 6 116 1.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS14910 6b8fb5236181ca74443f78f885bb27d7 646 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 263 601 2.7E-89 T 29-03-2018 IPR003776 YcaO-like domain A616_RS14910 6b8fb5236181ca74443f78f885bb27d7 646 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 263 646 3.1E-123 T 29-03-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component A616_RS14910 6b8fb5236181ca74443f78f885bb27d7 646 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 67 233 5.2E-49 T 29-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain A616_RS14910 6b8fb5236181ca74443f78f885bb27d7 646 Gene3D G3DSA:3.40.50.720 13 187 1.1E-9 T 29-03-2018 A616_RS28315 1439244b8ae9c03123c02441870e30e6 402 Pfam PF05977 Transmembrane secretion effector 2 387 1.0E-19 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS28315 1439244b8ae9c03123c02441870e30e6 402 Gene3D G3DSA:1.20.1250.20 203 399 1.5E-18 T 29-03-2018 A616_RS28315 1439244b8ae9c03123c02441870e30e6 402 SUPERFAMILY SSF103473 5 395 1.96E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS28315 1439244b8ae9c03123c02441870e30e6 402 Gene3D G3DSA:1.20.1250.20 1 193 1.1E-18 T 29-03-2018 A616_RS09575 f81c4f8a7b74c2d81e69ceff8e685471 239 SUPERFAMILY SSF48452 127 209 3.29E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS09575 f81c4f8a7b74c2d81e69ceff8e685471 239 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 8 224 6.1E-56 T 29-03-2018 IPR018708 Protein of unknown function DUF2225 A616_RS09575 f81c4f8a7b74c2d81e69ceff8e685471 239 SMART SM00028 176 209 6.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS09575 f81c4f8a7b74c2d81e69ceff8e685471 239 SMART SM00028 127 160 310.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS09575 f81c4f8a7b74c2d81e69ceff8e685471 239 Gene3D G3DSA:1.25.40.10 80 238 4.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 SUPERFAMILY SSF82714 694 774 5.23E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Gene3D G3DSA:1.20.1640.10 779 1008 1.3E-40 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Gene3D G3DSA:1.20.1640.10 291 500 5.2E-42 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Pfam PF00873 AcrB/AcrD/AcrF family 4 994 3.0E-185 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Gene3D G3DSA:3.30.2090.10 691 776 1.7E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 SUPERFAMILY SSF82693 43 132 4.45E-12 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 SUPERFAMILY SSF82693 552 636 1.38E-7 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 SUPERFAMILY SSF82866 774 998 3.14E-47 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Gene3D G3DSA:3.30.2090.10 179 265 4.0E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 SUPERFAMILY SSF82714 184 261 2.49E-7 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 SUPERFAMILY SSF82866 288 489 2.75E-39 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 6.1E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.1E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 6.1E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 6.1E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 6.1E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 598 612 6.1E-24 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Gene3D G3DSA:3.30.70.1430 553 644 1.7E-9 T 29-03-2018 A616_RS14070 bd7bc14624fc9071ea96648d2f65bb1a 1031 Gene3D G3DSA:3.30.70.1430 41 142 6.4E-17 T 29-03-2018 A616_RS05170 fb37e0486532f60ed99251d0346b23c7 378 Gene3D G3DSA:3.75.10.10 27 378 3.6E-107 T 29-03-2018 A616_RS05170 fb37e0486532f60ed99251d0346b23c7 378 SUPERFAMILY SSF55909 36 375 1.75E-104 T 29-03-2018 A616_RS05170 fb37e0486532f60ed99251d0346b23c7 378 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 42 375 1.1E-93 T 29-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 A616_RS15610 6d832a783fe00c07c94cd2eb657481e6 353 Pfam PF05076 Suppressor of fused protein (SUFU) 39 202 6.7E-47 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 A616_RS15610 6d832a783fe00c07c94cd2eb657481e6 353 PIRSF PIRSF038192 2 353 3.2E-145 T 29-03-2018 IPR017429 Suppressor of fused, bacterial A616_RS15610 6d832a783fe00c07c94cd2eb657481e6 353 SUPERFAMILY SSF103359 7 222 5.23E-83 T 29-03-2018 A616_RS08865 1fefd871e7d1c2315eea1705e85a8d8c 365 PIRSF PIRSF020979 1 361 3.4E-94 T 29-03-2018 IPR011215 Phosphoribosyl transferase A616_RS08865 1fefd871e7d1c2315eea1705e85a8d8c 365 Pfam PF15608 PELOTA RNA binding domain 279 358 2.5E-35 T 29-03-2018 IPR028157 PELOTA RNA-binding domain A616_RS08865 1fefd871e7d1c2315eea1705e85a8d8c 365 Pfam PF11202 Phosphoribosyl transferase (PRTase) 2 250 1.5E-109 T 29-03-2018 IPR011215 Phosphoribosyl transferase A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 PIRSF PIRSF006246 1 131 6.3E-45 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 SUPERFAMILY SSF50692 1 116 2.49E-42 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 129 60.856 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 8.2E-39 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 Gene3D G3DSA:2.40.40.20 1 117 5.2E-48 T 29-03-2018 A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 118 2.0E-26 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS17930 c3798d0af9019b21c0686a0513b35fbe 135 Pfam PF02261 Aspartate decarboxylase 1 114 6.1E-46 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS03160 860beed5a550c495ae1f671453b0e922 317 Gene3D G3DSA:3.40.50.300 24 190 2.5E-24 T 29-03-2018 A616_RS03160 860beed5a550c495ae1f671453b0e922 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 8.9E-66 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A616_RS03160 860beed5a550c495ae1f671453b0e922 317 Gene3D G3DSA:1.10.8.300 204 312 3.5E-34 T 29-03-2018 A616_RS03160 860beed5a550c495ae1f671453b0e922 317 SUPERFAMILY SSF52540 12 287 2.1E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03160 860beed5a550c495ae1f671453b0e922 317 PIRSF PIRSF002849 2 317 3.2E-137 T 29-03-2018 A616_RS13895 8fdd8bca2cc1cdc388d778eabc99eb9e 263 SUPERFAMILY SSF81648 23 160 2.35E-28 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A616_RS13895 8fdd8bca2cc1cdc388d778eabc99eb9e 263 SUPERFAMILY SSF46626 144 262 6.35E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS13895 8fdd8bca2cc1cdc388d778eabc99eb9e 263 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 195 259 5.3E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS13895 8fdd8bca2cc1cdc388d778eabc99eb9e 263 Gene3D G3DSA:1.20.810.10 16 168 3.9E-29 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A616_RS13895 8fdd8bca2cc1cdc388d778eabc99eb9e 263 Gene3D G3DSA:1.10.760.10 191 263 9.7E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS13895 8fdd8bca2cc1cdc388d778eabc99eb9e 263 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 72 159 1.1E-10 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A616_RS18845 6539f3e9e634112266269ff2383e4422 215 SUPERFAMILY SSF55469 10 209 1.1E-56 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS18845 6539f3e9e634112266269ff2383e4422 215 Pfam PF00881 Nitroreductase family 14 190 2.1E-33 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS18845 6539f3e9e634112266269ff2383e4422 215 Gene3D G3DSA:3.40.109.10 9 215 1.8E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.9E-85 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 Gene3D G3DSA:3.40.50.880 1 191 4.6E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00097 Anthranilate synthase component II signature 47 56 7.4E-37 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00097 Anthranilate synthase component II signature 119 131 7.4E-37 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00097 Anthranilate synthase component II signature 2 16 7.4E-37 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00097 Anthranilate synthase component II signature 74 85 7.4E-37 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00097 Anthranilate synthase component II signature 99 107 7.4E-37 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00097 Anthranilate synthase component II signature 164 177 7.4E-37 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 Pfam PF00117 Glutamine amidotransferase class-I 4 186 2.2E-55 T 29-03-2018 IPR017926 Glutamine amidotransferase A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.8E-5 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.8E-5 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.1E-13 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.1E-13 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.1E-13 T 29-03-2018 A616_RS01120 95310cb947cc7c893a471a1a1ef884ff 194 SUPERFAMILY SSF52317 1 189 1.11E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS17365 8cacc6bd4e0b24ae6c6f9f4b1d540180 499 Gene3D G3DSA:1.20.1270.70 315 372 4.9E-4 T 29-03-2018 A616_RS16545 e101b56fe31bee0ab85a9572287f6f2f 204 SUPERFAMILY SSF55811 71 202 5.01E-9 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS16545 e101b56fe31bee0ab85a9572287f6f2f 204 Gene3D G3DSA:3.90.79.10 5 200 1.7E-6 T 29-03-2018 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 238 35.036 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 Pfam PF01209 ubiE/COQ5 methyltransferase family 7 238 1.5E-84 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 238 4.3E-75 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 146 160 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 Gene3D G3DSA:3.40.50.150 1 231 9.7E-42 T 29-03-2018 A616_RS13755 cc6fb2186e678d49f28ddc55a493d534 239 SUPERFAMILY SSF53335 5 232 2.32E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS25945 f625e480430eafecdab6e45554d0d384 92 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 77 1.8E-37 T 29-03-2018 IPR018735 Protein of unknown function DUF2277 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Gene3D G3DSA:3.30.1040.20 66 93 6.0E-17 T 29-03-2018 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 ProSitePatterns PS00481 Thiol-activated cytolysins signature. 468 479 - T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Gene3D G3DSA:2.60.40.1430 403 506 1.4E-42 T 29-03-2018 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Pfam PF01289 Thiol-activated cytolysin 48 400 1.1E-147 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 SUPERFAMILY SSF56978 42 509 3.14E-199 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Gene3D G3DSA:3.90.840.10 298 381 1.1E-13 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Gene3D G3DSA:3.90.840.10 94 297 9.2E-59 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 129 147 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 322 339 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 484 504 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 85 107 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 370 397 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 113 129 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 409 426 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 426 442 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 55 72 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 187 202 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 268 291 7.8E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Gene3D G3DSA:3.30.1040.20 382 396 0.13 T 29-03-2018 A616_RS04275 5fd7121a2f64b4fcfcfa2db937747bd9 511 Pfam PF17440 Thiol-activated cytolysin beta sandwich domain 404 504 5.2E-42 T 29-03-2018 IPR035390 Thiol-activated cytolysin C-terminal A616_RS03875 864e65165d6958dc2d3d7e6d75fbcdad 280 Pfam PF08445 FR47-like protein 211 272 7.8E-10 T 29-03-2018 IPR013653 FR47-like GO:0016747 A616_RS03875 864e65165d6958dc2d3d7e6d75fbcdad 280 Gene3D G3DSA:3.40.630.30 33 277 3.1E-15 T 29-03-2018 A616_RS03875 864e65165d6958dc2d3d7e6d75fbcdad 280 SUPERFAMILY SSF55729 185 272 3.67E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 SUPERFAMILY SSF51230 87 163 4.97E-22 T 29-03-2018 IPR011053 Single hybrid motif A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 Gene3D G3DSA:2.40.50.100 38 165 1.4E-17 T 29-03-2018 A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 164 4.7E-53 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 Pfam PF00364 Biotin-requiring enzyme 90 161 1.7E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 125 138 1.5E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 124 1.5E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS13090 389862a252f4b420a027f0746f7ab7ba 166 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 93 106 1.5E-16 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 Gene3D G3DSA:3.20.20.120 129 373 1.5E-64 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 SMART SM00922 142 239 7.5E-29 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 124 7.0E-22 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 SUPERFAMILY SSF51604 112 361 2.23E-68 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 Pfam PF13378 Enolase C-terminal domain-like 145 356 2.5E-51 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 Gene3D G3DSA:3.30.390.10 1 128 1.5E-38 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS28340 b989e860d2c9e7be94211f48b78fabed 376 SUPERFAMILY SSF54826 1 125 5.01E-36 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 SUPERFAMILY SSF46894 132 230 6.24E-34 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 229 1.7E-31 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 Gene3D G3DSA:1.10.10.10 128 231 2.5E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 Pfam PF00072 Response regulator receiver domain 4 113 2.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 SUPERFAMILY SSF52172 1 129 3.7E-45 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 SMART SM00862 153 229 1.2E-31 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 Gene3D G3DSA:3.40.50.2300 1 127 1.3E-40 T 29-03-2018 A616_RS08005 7f7ea4abb76727ef5cf3479e20de08b3 231 SMART SM00448 2 113 5.0E-49 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03830 9faeba2ff6061e62a4a317af373fb20b 191 Pfam PF02223 Thymidylate kinase 9 137 2.4E-12 T 29-03-2018 A616_RS03830 9faeba2ff6061e62a4a317af373fb20b 191 Gene3D G3DSA:3.40.50.300 1 189 1.9E-10 T 29-03-2018 A616_RS03830 9faeba2ff6061e62a4a317af373fb20b 191 SUPERFAMILY SSF52540 1 165 6.17E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29310 0962f857cc751bd662e393a79ad09d26 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 362 9.8E-70 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS29310 0962f857cc751bd662e393a79ad09d26 366 Pfam PF03845 Spore germination protein 6 325 1.1E-62 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS28005 0955b71d7f2122f336fc02f26f32d715 358 SUPERFAMILY SSF48452 197 345 7.27E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28005 0955b71d7f2122f336fc02f26f32d715 358 Gene3D G3DSA:1.25.40.10 217 299 4.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS28005 0955b71d7f2122f336fc02f26f32d715 358 SUPERFAMILY SSF53448 1 142 7.97E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28005 0955b71d7f2122f336fc02f26f32d715 358 Pfam PF00535 Glycosyl transferase family 2 2 124 9.1E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS28005 0955b71d7f2122f336fc02f26f32d715 358 Gene3D G3DSA:3.90.550.10 1 216 1.0E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28005 0955b71d7f2122f336fc02f26f32d715 358 Gene3D G3DSA:1.25.40.10 300 353 0.037 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 Gene3D G3DSA:1.25.40.10 284 395 3.2E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 Pfam PF01381 Helix-turn-helix 15 69 4.9E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 SUPERFAMILY SSF48452 196 379 3.79E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 Gene3D G3DSA:1.25.40.10 137 283 6.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 SMART SM00530 14 70 4.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 Gene3D G3DSA:1.10.10.60 10 35 3.0E-7 T 29-03-2018 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 Pfam PF13181 Tetratricopeptide repeat 274 302 0.0014 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 Gene3D G3DSA:3.30.1190.10 36 120 1.8E-6 T 29-03-2018 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 SMART SM00028 350 383 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 SMART SM00028 196 229 0.024 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 SMART SM00028 270 303 0.018 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS25180 28c1ab258afe2e94d5b801902dc8f8b9 426 SUPERFAMILY SSF47413 9 73 7.6E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS30355 2a5e173a938875b8c84fc07a8014e86e 136 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 65 128 2.9E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS30355 2a5e173a938875b8c84fc07a8014e86e 136 SUPERFAMILY SSF54292 50 133 8.0E-17 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS30355 2a5e173a938875b8c84fc07a8014e86e 136 Gene3D G3DSA:3.10.20.30 42 136 1.6E-17 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS08940 6d1cdf261b0b4ca2c54635248e6aa69a 286 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 14 168 4.7E-54 T 29-03-2018 IPR019261 Domain of unknown function DUF2263 A616_RS08940 6d1cdf261b0b4ca2c54635248e6aa69a 286 SUPERFAMILY SSF52949 207 284 2.16E-7 T 29-03-2018 A616_RS08940 6d1cdf261b0b4ca2c54635248e6aa69a 286 PIRSF PIRSF014899 3 286 6.2E-92 T 29-03-2018 IPR012664 Conserved hypothetical protein CHP02452 A616_RS08940 6d1cdf261b0b4ca2c54635248e6aa69a 286 Gene3D G3DSA:3.40.220.10 205 286 9.2E-17 T 29-03-2018 A616_RS08940 6d1cdf261b0b4ca2c54635248e6aa69a 286 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 13 283 9.9E-85 T 29-03-2018 IPR012664 Conserved hypothetical protein CHP02452 A616_RS31015 ad41960767b82d934724c9d296968297 100 SUPERFAMILY SSF52794 1 98 3.92E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A616_RS31015 ad41960767b82d934724c9d296968297 100 Gene3D G3DSA:3.40.50.2300 1 100 3.5E-39 T 29-03-2018 A616_RS31015 ad41960767b82d934724c9d296968297 100 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 94 7.1E-37 T 29-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A616_RS31015 ad41960767b82d934724c9d296968297 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 5.6E-24 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 SUPERFAMILY SSF50249 204 301 2.06E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 Gene3D G3DSA:3.30.470.30 7 145 4.3E-31 T 29-03-2018 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 Pfam PF04679 ATP dependent DNA ligase C terminal region 212 301 2.3E-15 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 SUPERFAMILY SSF56091 15 196 7.67E-37 T 29-03-2018 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 Gene3D G3DSA:3.30.1490.70 146 186 2.7E-6 T 29-03-2018 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 26 34 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 Gene3D G3DSA:2.40.50.140 187 305 5.5E-15 T 29-03-2018 A616_RS20390 9a070e7ca8ace391ef4e76da29692d08 313 Pfam PF01068 ATP dependent DNA ligase domain 21 196 6.1E-31 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A616_RS23265 d59732dd468faf4e5df497e1652573ed 268 Gene3D G3DSA:2.60.40.1120 23 95 3.8E-5 T 29-03-2018 A616_RS23265 d59732dd468faf4e5df497e1652573ed 268 SUPERFAMILY SSF49452 33 87 1.35E-5 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 TIGRFAM TIGR01634 tail_P2_I: phage tail protein I 507 582 5.5E-8 T 29-03-2018 IPR006521 Tail protein I A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 Pfam PF09684 Phage tail protein (Tail_P2_I) 503 632 1.4E-16 T 29-03-2018 IPR006521 Tail protein I A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 Gene3D G3DSA:2.120.10.30 32 201 0.017 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 469 584 7.1E-34 T 29-03-2018 IPR011748 Uncharacterised protein family, phage tail-like A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 Gene3D G3DSA:2.120.10.30 202 442 1.3E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 SUPERFAMILY SSF63829 211 324 5.56E-11 T 29-03-2018 A616_RS23200 4eb2bcf55446d233986862e87d81665e 702 SUPERFAMILY SSF63829 49 163 5.56E-11 T 29-03-2018 A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 2.3E-63 T 29-03-2018 A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 Gene3D G3DSA:3.40.50.720 45 254 8.4E-68 T 29-03-2018 A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 Gene3D G3DSA:3.40.50.720 1 44 8.2E-10 T 29-03-2018 A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 9.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 9.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 9.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 9.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 9.7E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 SUPERFAMILY SSF51735 8 252 7.91E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS18920 c4dd61f69b4de377169e3fb0898468ea 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22810 ea8fb6d8308fb9feaa3384defbe44bd7 478 SUPERFAMILY SSF56601 5 126 1.94E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS22810 ea8fb6d8308fb9feaa3384defbe44bd7 478 SUPERFAMILY SSF56601 155 358 1.94E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS22810 ea8fb6d8308fb9feaa3384defbe44bd7 478 Gene3D G3DSA:3.40.710.10 2 372 2.0E-77 T 29-03-2018 A616_RS22810 ea8fb6d8308fb9feaa3384defbe44bd7 478 Pfam PF00144 Beta-lactamase 9 362 1.3E-60 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 Gene3D G3DSA:1.10.287.950 442 688 3.5E-38 T 29-03-2018 A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 Gene3D G3DSA:1.10.287.950 250 441 0.011 T 29-03-2018 A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 492 638 1.1E-25 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 SMART SM00304 326 381 1.6E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 SMART SM00283 392 687 2.3E-16 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 SUPERFAMILY SSF58104 416 687 4.84E-43 T 29-03-2018 A616_RS28295 5beb7a3b81930a54f66040acaa721e14 688 SUPERFAMILY SSF58104 357 383 4.84E-43 T 29-03-2018 A616_RS17880 8a434fe9257eefad82664afeb31bb463 196 Gene3D G3DSA:3.40.50.360 1 196 3.8E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS17880 8a434fe9257eefad82664afeb31bb463 196 Pfam PF02525 Flavodoxin-like fold 1 173 2.6E-42 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS17880 8a434fe9257eefad82664afeb31bb463 196 SUPERFAMILY SSF52218 1 190 2.51E-47 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS17055 8562692e5fbd9e5707e951e03cbb8d30 122 Pfam PF10711 Hypothetical protein (DUF2513) 2 98 2.7E-19 T 29-03-2018 IPR019650 Protein of unknown function DUF2513 A616_RS10685 882236857247b13086e71f7b5a7dfc3e 106 Pfam PF02699 Preprotein translocase subunit 6 81 5.0E-31 T 29-03-2018 IPR003849 Preprotein translocase YajC A616_RS10685 882236857247b13086e71f7b5a7dfc3e 106 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 5.6E-16 T 29-03-2018 IPR003849 Preprotein translocase YajC A616_RS10685 882236857247b13086e71f7b5a7dfc3e 106 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 5.6E-16 T 29-03-2018 IPR003849 Preprotein translocase YajC A616_RS10685 882236857247b13086e71f7b5a7dfc3e 106 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 2.9E-30 T 29-03-2018 IPR003849 Preprotein translocase YajC A616_RS10685 882236857247b13086e71f7b5a7dfc3e 106 SMART SM01323 2 84 1.8E-45 T 29-03-2018 IPR003849 Preprotein translocase YajC A616_RS21265 12d32af0146d9e10f057b42495e78fd7 115 Pfam PF06947 Protein of unknown function (DUF1290) 22 107 3.2E-34 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 A616_RS21265 12d32af0146d9e10f057b42495e78fd7 115 PIRSF PIRSF018579 1 113 1.8E-41 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 A616_RS18085 23c3d81fb0d51935d903043423ee3bcb 121 SUPERFAMILY SSF46785 16 111 7.53E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18085 23c3d81fb0d51935d903043423ee3bcb 121 Gene3D G3DSA:1.10.10.10 21 120 5.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18085 23c3d81fb0d51935d903043423ee3bcb 121 Pfam PF01638 HxlR-like helix-turn-helix 23 110 3.1E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS09300 af6eb2da1403247c471d556bcfc6a58d 210 Pfam PF04116 Fatty acid hydroxylase superfamily 43 184 2.5E-16 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 A616_RS05065 613a50ba95222c3930b22f7aa80e39d4 43 Pfam PF08176 Small acid-soluble spore protein K family 2 40 6.8E-7 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 A616_RS09450 28131a7be9087ac5c114b56d3756be83 295 SUPERFAMILY SSF47240 20 277 1.11E-43 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS09450 28131a7be9087ac5c114b56d3756be83 295 Gene3D G3DSA:1.10.620.20 1 285 1.2E-52 T 29-03-2018 A616_RS09450 28131a7be9087ac5c114b56d3756be83 295 Pfam PF00268 Ribonucleotide reductase, small chain 21 263 1.2E-18 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS22640 732a1294fc247b751f94c7433456f2ea 216 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 182 9.5E-67 T 29-03-2018 IPR022301 Integral membrane protein YjbE A616_RS22640 732a1294fc247b751f94c7433456f2ea 216 Pfam PF03741 Integral membrane protein TerC family 11 181 7.1E-44 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 SMART SM00304 304 357 1.5E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Gene3D G3DSA:3.30.450.20 52 159 2.5E-13 T 29-03-2018 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 SUPERFAMILY SSF58104 392 661 4.05E-76 T 29-03-2018 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 SUPERFAMILY SSF58104 329 359 4.05E-76 T 29-03-2018 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Pfam PF02743 Cache domain 43 266 1.8E-30 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 431 614 1.2E-49 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Pfam PF00672 HAMP domain 304 353 4.2E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 SMART SM00283 386 661 3.0E-84 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Gene3D G3DSA:1.10.287.950 277 414 6.5E-8 T 29-03-2018 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Gene3D G3DSA:1.10.287.950 415 662 4.8E-56 T 29-03-2018 A616_RS30465 ea1682ff166712f92924bfdad918af8b 662 Gene3D G3DSA:3.30.450.20 160 276 2.7E-22 T 29-03-2018 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 264 1.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 SUPERFAMILY SSF55874 256 424 6.29E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 Gene3D G3DSA:3.30.565.10 268 428 2.9E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 Gene3D G3DSA:3.30.450.40 31 184 1.3E-9 T 29-03-2018 IPR029016 GAF domain-like A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 8.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 8.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 8.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 8.7E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 420 1.0E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 SMART SM00388 201 266 1.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 Gene3D G3DSA:1.10.287.130 189 262 7.4E-17 T 29-03-2018 A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 SMART SM00387 308 422 3.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 SUPERFAMILY SSF55781 36 185 1.66E-8 T 29-03-2018 IPR029016 GAF domain-like A616_RS25755 895e111eeb7a2bc35b8285c094984cf6 437 SUPERFAMILY SSF47384 196 264 1.96E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS04905 c032c38bad634f1dd12c29c65b30f274 482 PIRSF PIRSF000484 3 482 1.2E-153 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A616_RS04905 c032c38bad634f1dd12c29c65b30f274 482 SUPERFAMILY SSF51690 138 479 1.47E-125 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A616_RS04905 c032c38bad634f1dd12c29c65b30f274 482 Gene3D G3DSA:3.20.140.10 2 379 5.6E-128 T 29-03-2018 A616_RS04905 c032c38bad634f1dd12c29c65b30f274 482 SUPERFAMILY SSF54675 6 137 8.1E-46 T 29-03-2018 A616_RS04905 c032c38bad634f1dd12c29c65b30f274 482 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 467 1.8E-176 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 A616_RS04905 c032c38bad634f1dd12c29c65b30f274 482 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 154 355 4.5E-10 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 Gene3D G3DSA:3.40.50.720 1 255 2.4E-56 T 29-03-2018 A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 198 0.0056 T 29-03-2018 A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 Pfam PF00106 short chain dehydrogenase 7 203 9.2E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 SUPERFAMILY SSF51735 7 252 1.95E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 5.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 5.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.5E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25690 34d021e95052539aa4771420fca8d5b0 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS23435 698d115c9f634629413084edb8fee3a6 362 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 115 256 3.0E-43 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS23435 698d115c9f634629413084edb8fee3a6 362 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 114 256 4.1E-44 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 SUPERFAMILY SSF56801 10 523 2.35E-148 T 29-03-2018 A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 Gene3D G3DSA:3.40.50.980 181 330 1.1E-37 T 29-03-2018 A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 Gene3D G3DSA:3.40.50.980 6 180 1.1E-32 T 29-03-2018 A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 Gene3D G3DSA:2.30.38.10 331 416 3.0E-24 T 29-03-2018 A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 Gene3D G3DSA:3.30.300.30 419 527 5.8E-29 T 29-03-2018 A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 Pfam PF00501 AMP-binding enzyme 16 423 6.8E-83 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 8.5E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS14425 5fb629c8a330f19f9db75c5659affa92 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 146 160 2.9E-35 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 246 257 2.9E-35 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 268 277 2.9E-35 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 180 198 2.9E-35 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 217 234 2.9E-35 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 298 38.356 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 SUPERFAMILY SSF52096 44 298 9.95E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 Gene3D G3DSA:3.90.226.10 31 304 9.1E-65 T 29-03-2018 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 29 299 1.1E-119 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07940 1532d633a6ccfb422330a4eb23d7a2c4 314 Pfam PF01039 Carboxyl transferase domain 114 308 5.9E-16 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A616_RS31065 231995863f19184737b3ac15d66d6156 286 Gene3D G3DSA:3.40.710.10 24 286 1.1E-44 T 29-03-2018 A616_RS31065 231995863f19184737b3ac15d66d6156 286 SUPERFAMILY SSF56601 1 285 7.52E-67 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS31065 231995863f19184737b3ac15d66d6156 286 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 127 144 1.1E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS31065 231995863f19184737b3ac15d66d6156 286 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 154 167 1.1E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS31065 231995863f19184737b3ac15d66d6156 286 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 74 85 1.1E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS31065 231995863f19184737b3ac15d66d6156 286 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 44 266 2.4E-62 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A616_RS19280 28b0d0dc83fea803579508e9db1d53fd 154 SUPERFAMILY SSF55729 12 140 1.39E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS19280 28b0d0dc83fea803579508e9db1d53fd 154 Pfam PF00583 Acetyltransferase (GNAT) family 27 139 1.1E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS19280 28b0d0dc83fea803579508e9db1d53fd 154 Gene3D G3DSA:3.40.630.30 10 152 2.3E-24 T 29-03-2018 A616_RS22085 89a093775ff4601a1eba078baaafad4f 272 SUPERFAMILY SSF53474 51 220 9.7E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS22085 89a093775ff4601a1eba078baaafad4f 272 Gene3D G3DSA:3.40.50.1820 2 242 8.9E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS22085 89a093775ff4601a1eba078baaafad4f 272 Pfam PF01764 Lipase (class 3) 67 196 5.5E-31 T 29-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 A616_RS05395 67f2a0a7dd6f054019e1d09bcd7cfaa1 424 Pfam PF04346 Ethanolamine utilisation protein, EutH 4 385 7.0E-126 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 A616_RS05395 67f2a0a7dd6f054019e1d09bcd7cfaa1 424 PIRSF PIRSF019466 2 402 2.9E-126 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PIRSF PIRSF000532 1 319 2.9E-120 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 Pfam PF00365 Phosphofructokinase 3 275 1.8E-109 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 Gene3D G3DSA:3.40.50.450 195 300 3.8E-22 T 29-03-2018 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 6.1E-134 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 47.018 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 Gene3D G3DSA:3.40.50.450 1 194 4.0E-75 T 29-03-2018 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.7E-87 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS07950 d27a13437cd17de5520ca108060be6d3 319 SUPERFAMILY SSF53784 1 315 5.62E-116 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 Pfam PF01022 Bacterial regulatory protein, arsR family 11 56 2.8E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 Gene3D G3DSA:1.10.10.10 1 106 6.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 8.7E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 8.7E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 8.7E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 SUPERFAMILY SSF46785 8 93 2.14E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27750 3dbf7eee7aa44342d249236d55959539 106 SMART SM00418 4 81 8.4E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS29810 94befbd570120863bdc1a25df3f2dde4 242 Pfam PF01551 Peptidase family M23 130 228 1.3E-24 T 29-03-2018 IPR016047 Peptidase M23 A616_RS29810 94befbd570120863bdc1a25df3f2dde4 242 Gene3D G3DSA:2.70.70.10 85 242 3.0E-31 T 29-03-2018 A616_RS29810 94befbd570120863bdc1a25df3f2dde4 242 SUPERFAMILY SSF51261 124 232 1.99E-27 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS27660 3705be60f6a27618f886437c26a82fac 308 Pfam PF00005 ABC transporter 17 160 4.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27660 3705be60f6a27618f886437c26a82fac 308 SMART SM00382 26 208 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27660 3705be60f6a27618f886437c26a82fac 308 SUPERFAMILY SSF52540 1 228 1.3E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27660 3705be60f6a27618f886437c26a82fac 308 Gene3D G3DSA:3.40.50.300 1 258 1.7E-69 T 29-03-2018 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 SMART SM00304 217 270 4.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 Pfam PF00672 HAMP domain 219 265 1.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 Gene3D G3DSA:1.10.287.950 327 575 6.6E-63 T 29-03-2018 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 Gene3D G3DSA:1.10.287.950 26 326 2.9E-10 T 29-03-2018 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 SMART SM00283 299 574 2.4E-96 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 344 527 6.1E-53 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 190 6.3E-25 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 SUPERFAMILY SSF58104 244 272 6.67E-79 T 29-03-2018 A616_RS04960 c54f9d6e9cab919a44ce425d85913c51 575 SUPERFAMILY SSF58104 305 574 6.67E-79 T 29-03-2018 A616_RS04745 163b628da12c7935eac730e71a9b96f9 271 Gene3D G3DSA:3.90.25.10 144 271 1.2E-4 T 29-03-2018 A616_RS04745 163b628da12c7935eac730e71a9b96f9 271 Gene3D G3DSA:3.40.50.720 1 143 3.0E-19 T 29-03-2018 A616_RS04745 163b628da12c7935eac730e71a9b96f9 271 SUPERFAMILY SSF51735 3 233 8.22E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04745 163b628da12c7935eac730e71a9b96f9 271 Pfam PF05368 NmrA-like family 3 223 2.7E-20 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 PIRSF PIRSF000447 1 410 2.4E-171 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 SMART SM00825 Beta-ketoacyl synthase 4 410 4.1E-16 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 3.8E-35 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 Gene3D G3DSA:3.40.47.10 259 410 1.3E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 SUPERFAMILY SSF53901 1 250 4.03E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 2.5E-180 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 SUPERFAMILY SSF53901 212 409 1.34E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 245 2.5E-63 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A616_RS24095 9c813f02a19d4595342cbf468b1ef1d8 410 Gene3D G3DSA:3.40.47.10 4 258 4.2E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS28380 7f3ee471303e0c3d06132270728c1dfb 284 SUPERFAMILY SSF161098 79 267 4.58E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28380 7f3ee471303e0c3d06132270728c1dfb 284 Gene3D G3DSA:1.10.3720.10 26 274 2.9E-43 T 29-03-2018 A616_RS28380 7f3ee471303e0c3d06132270728c1dfb 284 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 15 61 2.7E-5 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS28380 7f3ee471303e0c3d06132270728c1dfb 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 283 6.5E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 Gene3D G3DSA:3.30.565.10 436 579 5.2E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 Pfam PF13492 GAF domain 253 362 3.5E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 SMART SM00387 471 579 8.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 Pfam PF06580 Histidine kinase 377 456 8.9E-24 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 SUPERFAMILY SSF55874 440 577 4.58E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 Pfam PF07694 5TMR of 5TMR-LYT 25 205 2.6E-42 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 Gene3D G3DSA:3.30.450.40 224 369 1.7E-4 T 29-03-2018 IPR029016 GAF domain-like A616_RS12285 bdcd16599ff07f65ae87e389f262097f 583 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 578 1.0E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 PIRSF PIRSF006493 1 317 1.4E-99 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 255 7.5E-95 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 177 3.7E-41 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 SMART SM00559 52 180 3.1E-40 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 SUPERFAMILY SSF100939 2 255 9.61E-50 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 Gene3D G3DSA:2.40.290.10 1 180 3.4E-33 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain A616_RS20370 8fd3365d17cb640041c39463c3c1754a 319 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 253 34.303 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type A616_RS19410 9da0823dfed5ec26e841f0a69f595a8f 168 SUPERFAMILY SSF56349 89 166 3.83E-15 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS19410 9da0823dfed5ec26e841f0a69f595a8f 168 Gene3D G3DSA:1.10.443.10 7 163 1.7E-11 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS19410 9da0823dfed5ec26e841f0a69f595a8f 168 Pfam PF00589 Phage integrase family 73 153 4.1E-8 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS04615 e0c86f551cc72a79e5dabfd91f6ff355 354 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 202 2.5E-8 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS04615 e0c86f551cc72a79e5dabfd91f6ff355 354 SUPERFAMILY SSF55347 132 319 2.88E-30 T 29-03-2018 A616_RS04615 e0c86f551cc72a79e5dabfd91f6ff355 354 SUPERFAMILY SSF51735 3 154 2.15E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04615 e0c86f551cc72a79e5dabfd91f6ff355 354 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 1.1E-31 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS04615 e0c86f551cc72a79e5dabfd91f6ff355 354 Gene3D G3DSA:3.30.360.10 136 352 6.0E-44 T 29-03-2018 A616_RS04615 e0c86f551cc72a79e5dabfd91f6ff355 354 Gene3D G3DSA:3.40.50.720 1 135 2.8E-40 T 29-03-2018 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 Gene3D G3DSA:3.40.190.10 161 309 3.2E-23 T 29-03-2018 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 107 120 1.5E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 260 279 1.5E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 105 1.5E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 160 174 1.5E-7 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 SUPERFAMILY SSF53850 41 355 5.65E-64 T 29-03-2018 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 Pfam PF13343 Bacterial extracellular solute-binding protein 92 342 5.1E-31 T 29-03-2018 A616_RS31135 7b8e26c9628ac7256154031dd8482332 357 Gene3D G3DSA:3.40.190.10 40 160 3.6E-16 T 29-03-2018 A616_RS05695 fc09247cefe4e350b606de6363819b7b 231 Gene3D G3DSA:1.20.120.330 78 227 0.095 T 29-03-2018 A616_RS05695 fc09247cefe4e350b606de6363819b7b 231 Pfam PF04012 PspA/IM30 family 2 216 1.0E-46 T 29-03-2018 IPR007157 PspA/IM30 A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 21 278 3.0E-113 T 29-03-2018 IPR023705 Nucleoid occlusion protein A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 Gene3D G3DSA:1.10.10.730 113 160 2.8E-18 T 29-03-2018 A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 Pfam PF02195 ParB-like nuclease domain 24 111 3.6E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 20 197 3.5E-59 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 SUPERFAMILY SSF110849 22 159 3.19E-34 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 SMART SM00470 23 112 3.9E-36 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS32260 96e01ade29cbc9ada881ac87d8745c43 284 Gene3D G3DSA:3.90.1530.10 12 112 4.5E-37 T 29-03-2018 A616_RS21025 3899b6a32a80a99a2e694cd2e7e1954d 179 Pfam PF00156 Phosphoribosyl transferase domain 7 146 4.6E-22 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS21025 3899b6a32a80a99a2e694cd2e7e1954d 179 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 38.692 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A616_RS21025 3899b6a32a80a99a2e694cd2e7e1954d 179 Gene3D G3DSA:3.40.50.2020 2 178 2.8E-38 T 29-03-2018 A616_RS21025 3899b6a32a80a99a2e694cd2e7e1954d 179 SUPERFAMILY SSF53271 4 167 4.2E-45 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 Gene3D G3DSA:3.30.420.40 1 247 5.6E-88 T 29-03-2018 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 4.0E-63 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 251 9.9E-88 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 SUPERFAMILY SSF53067 4 254 5.07E-96 T 29-03-2018 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 Hamap MF_00186 Glycerol kinase [glpK]. 3 496 59.792 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 PIRSF PIRSF000538 3 498 5.0E-185 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 494 2.8E-229 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 SUPERFAMILY SSF53067 254 493 7.99E-85 T 29-03-2018 A616_RS27685 86a0f0c489ca8c9ce360f4e8d6eb1749 499 Gene3D G3DSA:3.30.420.40 248 499 6.3E-80 T 29-03-2018 A616_RS01255 0801eca47f7d8bb126d601d3aaa2ea82 362 Pfam PF01938 TRAM domain 293 346 3.9E-6 T 29-03-2018 IPR002792 TRAM domain A616_RS01255 0801eca47f7d8bb126d601d3aaa2ea82 362 SUPERFAMILY SSF88723 164 290 5.4E-23 T 29-03-2018 IPR029060 PIN domain-like A616_RS01255 0801eca47f7d8bb126d601d3aaa2ea82 362 Gene3D G3DSA:3.40.50.1010 158 293 3.3E-26 T 29-03-2018 IPR029060 PIN domain-like A616_RS01255 0801eca47f7d8bb126d601d3aaa2ea82 362 SMART SM00670 162 269 4.0E-11 T 29-03-2018 IPR002716 PIN domain A616_RS24770 a32fcbf87833c4c5ef7555dcbe9a4c2f 118 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.8E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24770 a32fcbf87833c4c5ef7555dcbe9a4c2f 118 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.8E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24770 a32fcbf87833c4c5ef7555dcbe9a4c2f 118 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.8E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24770 a32fcbf87833c4c5ef7555dcbe9a4c2f 118 SUPERFAMILY SSF46785 3 86 2.87E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24770 a32fcbf87833c4c5ef7555dcbe9a4c2f 118 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.0E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24770 a32fcbf87833c4c5ef7555dcbe9a4c2f 118 Gene3D G3DSA:1.10.10.10 2 94 2.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30270 b8baf59d3141651ca10ccd07c27e2d1b 431 SMART SM00471 56 185 3.1E-13 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS30270 b8baf59d3141651ca10ccd07c27e2d1b 431 Gene3D G3DSA:1.10.3210.10 9 310 3.4E-77 T 29-03-2018 A616_RS30270 b8baf59d3141651ca10ccd07c27e2d1b 431 SUPERFAMILY SSF109604 8 409 4.36E-115 T 29-03-2018 A616_RS30270 b8baf59d3141651ca10ccd07c27e2d1b 431 Pfam PF01966 HD domain 60 129 7.6E-14 T 29-03-2018 IPR006674 HD domain A616_RS18240 e6db0967d183513c592c6d9237d17d36 335 SUPERFAMILY SSF51695 43 289 5.02E-40 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS18240 e6db0967d183513c592c6d9237d17d36 335 Gene3D G3DSA:3.20.20.190 30 335 2.4E-42 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS18240 e6db0967d183513c592c6d9237d17d36 335 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 49 183 4.8E-20 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 2.6E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 SUPERFAMILY SSF52540 4 251 9.26E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 316 4.4E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 Gene3D G3DSA:3.40.50.300 1 324 3.3E-80 T 29-03-2018 A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 SMART SM00382 33 231 4.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03280 3fa6b4c27c2f9dbb0195249b036ad7e7 324 Pfam PF00005 ABC transporter 25 181 2.3E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 458 34.595 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 369 1.6E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Gene3D G3DSA:1.20.120.430 286 458 1.2E-29 T 29-03-2018 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 SUPERFAMILY SSF52540 201 374 2.81E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS32285 4f276a4807a552569e39852d1faf638d 458 SUPERFAMILY SSF52540 78 167 2.81E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Pfam PF01926 50S ribosome-binding GTPase 224 335 3.5E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 124 3.3E-40 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 SUPERFAMILY SSF116878 383 458 1.96E-49 T 29-03-2018 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 SUPERFAMILY SSF116878 126 224 1.96E-49 T 29-03-2018 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Gene3D G3DSA:3.30.1360.120 1 125 7.9E-45 T 29-03-2018 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 458 5.5E-132 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Gene3D G3DSA:1.20.120.430 126 285 5.9E-30 T 29-03-2018 A616_RS32285 4f276a4807a552569e39852d1faf638d 458 Pfam PF12631 MnmE helical domain 127 455 2.6E-61 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 A616_RS19745 98f80f03c1a2abfc3564401b9033ee63 300 Gene3D G3DSA:3.40.50.720 1 136 9.3E-8 T 29-03-2018 A616_RS19745 98f80f03c1a2abfc3564401b9033ee63 300 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 122 6.9E-32 T 29-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal A616_RS19745 98f80f03c1a2abfc3564401b9033ee63 300 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 4 289 2.2E-125 T 29-03-2018 IPR014215 Dipicolinic acid synthetase subunit A A616_RS19745 98f80f03c1a2abfc3564401b9033ee63 300 SUPERFAMILY SSF51735 135 269 7.66E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS19745 98f80f03c1a2abfc3564401b9033ee63 300 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 288 3.1E-7 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A616_RS19745 98f80f03c1a2abfc3564401b9033ee63 300 Gene3D G3DSA:3.40.50.720 137 272 1.3E-21 T 29-03-2018 A616_RS25135 c7adceaeed395cb0fbebdedcc4960d12 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS25135 c7adceaeed395cb0fbebdedcc4960d12 479 Gene3D G3DSA:3.40.605.10 1 261 2.5E-87 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS25135 c7adceaeed395cb0fbebdedcc4960d12 479 SUPERFAMILY SSF53720 3 476 5.63E-146 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS25135 c7adceaeed395cb0fbebdedcc4960d12 479 Gene3D G3DSA:3.40.309.10 262 447 4.7E-59 T 29-03-2018 A616_RS25135 c7adceaeed395cb0fbebdedcc4960d12 479 Pfam PF00171 Aldehyde dehydrogenase family 11 472 6.2E-150 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS26245 0c44b3741db334829fb330eec51c4d7c 256 SUPERFAMILY SSF53807 2 254 2.9E-59 T 29-03-2018 A616_RS26245 0c44b3741db334829fb330eec51c4d7c 256 Gene3D G3DSA:3.40.50.1980 106 256 1.2E-34 T 29-03-2018 A616_RS26245 0c44b3741db334829fb330eec51c4d7c 256 Pfam PF01497 Periplasmic binding protein 3 230 4.1E-36 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS26245 0c44b3741db334829fb330eec51c4d7c 256 Gene3D G3DSA:3.40.50.1980 1 105 1.9E-24 T 29-03-2018 A616_RS15555 83384645ce01fd410b795efa4d50d006 230 Gene3D G3DSA:1.10.10.10 171 230 1.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15555 83384645ce01fd410b795efa4d50d006 230 SUPERFAMILY SSF46894 161 230 1.67E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS15555 83384645ce01fd410b795efa4d50d006 230 SUPERFAMILY SSF55781 9 182 2.63E-8 T 29-03-2018 IPR029016 GAF domain-like A616_RS15555 83384645ce01fd410b795efa4d50d006 230 Gene3D G3DSA:3.30.450.40 5 170 2.0E-5 T 29-03-2018 IPR029016 GAF domain-like A616_RS15555 83384645ce01fd410b795efa4d50d006 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 3.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15555 83384645ce01fd410b795efa4d50d006 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 3.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15555 83384645ce01fd410b795efa4d50d006 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 3.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15555 83384645ce01fd410b795efa4d50d006 230 SMART SM00421 167 224 2.1E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS15555 83384645ce01fd410b795efa4d50d006 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 169 221 5.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS26555 135db6578403430ca074994cd3c2c1bf 180 Gene3D G3DSA:3.30.70.100 1 170 9.8E-7 T 29-03-2018 A616_RS26555 135db6578403430ca074994cd3c2c1bf 180 Pfam PF16291 Domain of unknown function (DUF4937 2 90 1.5E-34 T 29-03-2018 IPR032555 Domain of unknown function DUF4937 A616_RS26555 135db6578403430ca074994cd3c2c1bf 180 SUPERFAMILY SSF54909 1 79 5.85E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS15715 b2c2e5fc0ee81c75f05cf3471925752d 122 Gene3D G3DSA:3.10.450.50 2 122 1.7E-11 T 29-03-2018 A616_RS15715 b2c2e5fc0ee81c75f05cf3471925752d 122 SUPERFAMILY SSF54427 6 121 1.23E-29 T 29-03-2018 IPR032710 NTF2-like domain A616_RS15715 b2c2e5fc0ee81c75f05cf3471925752d 122 Pfam PF12893 Putative lumazine-binding 7 119 5.8E-26 T 29-03-2018 A616_RS06670 0e1dea9d481fd561620199c0e9f7eeea 262 Pfam PF00293 NUDIX domain 49 164 1.6E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS06670 0e1dea9d481fd561620199c0e9f7eeea 262 ProSitePatterns PS00893 Nudix box signature. 71 92 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS06670 0e1dea9d481fd561620199c0e9f7eeea 262 SUPERFAMILY SSF46785 179 256 5.98E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06670 0e1dea9d481fd561620199c0e9f7eeea 262 Gene3D G3DSA:1.10.10.10 188 254 2.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06670 0e1dea9d481fd561620199c0e9f7eeea 262 SUPERFAMILY SSF55811 46 174 1.25E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS06670 0e1dea9d481fd561620199c0e9f7eeea 262 Gene3D G3DSA:3.90.79.10 18 187 7.6E-35 T 29-03-2018 A616_RS28530 4621fd6c52ecb6e11bdee046e2d996d7 198 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 20 197 1.0E-69 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 A616_RS28530 4621fd6c52ecb6e11bdee046e2d996d7 198 SUPERFAMILY SSF81452 8 196 1.57E-54 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28530 4621fd6c52ecb6e11bdee046e2d996d7 198 Pfam PF00510 Cytochrome c oxidase subunit III 20 196 5.4E-15 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS28530 4621fd6c52ecb6e11bdee046e2d996d7 198 Gene3D G3DSA:1.20.120.80 13 198 1.2E-49 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS19605 589bb0bcbb55d65a0195a566642e33ab 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 263 9.7E-108 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like A616_RS19605 589bb0bcbb55d65a0195a566642e33ab 264 Pfam PF13277 YmdB-like protein 4 254 1.5E-111 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like A616_RS19605 589bb0bcbb55d65a0195a566642e33ab 264 SUPERFAMILY SSF56300 1 256 1.01E-88 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS19605 589bb0bcbb55d65a0195a566642e33ab 264 PIRSF PIRSF004789 1 263 4.4E-105 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like A616_RS19605 589bb0bcbb55d65a0195a566642e33ab 264 Gene3D G3DSA:3.60.21.10 1 264 1.6E-47 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS27780 fe7044eefcb9c2e1e031727ec8a42827 508 PIRSF PIRSF005690 15 508 8.6E-140 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS27780 fe7044eefcb9c2e1e031727ec8a42827 508 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 29 494 4.4E-140 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 290 1.8E-82 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 Gene3D G3DSA:3.40.710.10 25 326 1.7E-50 T 29-03-2018 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 Gene3D G3DSA:2.60.410.10 327 413 1.1E-12 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 312 413 2.8E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 SMART SM00936 307 413 1.6E-10 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 SUPERFAMILY SSF56601 2 310 2.61E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 SUPERFAMILY SSF69189 302 390 3.53E-14 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 1.6E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 129 146 1.6E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS00215 ea7fd6390b0a8ec7a6a87944b0374802 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 156 169 1.6E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS30455 9ef7be55bde9a1c9c12b42af09d52425 205 SMART SM00317 4 118 0.0015 T 29-03-2018 IPR001214 SET domain GO:0005515 A616_RS30455 9ef7be55bde9a1c9c12b42af09d52425 205 Pfam PF00856 SET domain 73 112 9.4E-6 T 29-03-2018 IPR001214 SET domain GO:0005515 A616_RS30455 9ef7be55bde9a1c9c12b42af09d52425 205 SUPERFAMILY SSF82199 2 123 7.59E-17 T 29-03-2018 A616_RS30455 9ef7be55bde9a1c9c12b42af09d52425 205 Gene3D G3DSA:2.170.270.10 1 118 9.4E-15 T 29-03-2018 A616_RS28330 0c700df4c07ea8c373d1e38229b25a92 362 Gene3D G3DSA:3.60.60.10 106 356 2.9E-31 T 29-03-2018 A616_RS28330 0c700df4c07ea8c373d1e38229b25a92 362 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 120 349 3.6E-24 T 29-03-2018 IPR005079 Peptidase C45 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 Gene3D G3DSA:2.40.30.40 69 160 2.0E-34 T 29-03-2018 IPR023367 Peptidase M42, domain 2 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 PIRSF PIRSF001123 1 359 2.0E-135 T 29-03-2018 IPR008007 Peptidase M42 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 Pfam PF05343 M42 glutamyl aminopeptidase 45 341 7.2E-105 T 29-03-2018 IPR008007 Peptidase M42 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 Gene3D G3DSA:3.40.630.10 163 357 2.3E-41 T 29-03-2018 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 SUPERFAMILY SSF101821 70 179 7.94E-32 T 29-03-2018 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 SUPERFAMILY SSF53187 171 356 4.28E-66 T 29-03-2018 A616_RS16010 c4534323aa0f5a429734780d98f4f97e 359 SUPERFAMILY SSF53187 5 80 4.28E-66 T 29-03-2018 A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 SUPERFAMILY SSF55326 408 574 4.19E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 747 337.512 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Gene3D G3DSA:3.90.650.10 573 747 2.0E-37 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 25 745 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Pfam PF00586 AIR synthase related protein, N-terminal domain 449 566 4.3E-26 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Pfam PF00586 AIR synthase related protein, N-terminal domain 91 196 4.0E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Pfam PF02769 AIR synthase related protein, C-terminal domain 580 715 7.8E-20 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Pfam PF02769 AIR synthase related protein, C-terminal domain 210 361 3.7E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 PIRSF PIRSF001587 9 747 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Gene3D G3DSA:3.30.1330.10 51 185 7.6E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Gene3D G3DSA:3.90.650.10 186 379 6.2E-38 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 SUPERFAMILY SSF56042 208 434 1.94E-58 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 SUPERFAMILY SSF56042 575 745 1.02E-41 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 SUPERFAMILY SSF55326 20 203 1.05E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS03560 20384e7d4a6ff236346474c487959c5f 747 Gene3D G3DSA:3.30.1330.10 423 571 1.1E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain A616_RS07735 0b3563ffc5cca6e624d5cc5a50528f68 345 Pfam PF00144 Beta-lactamase 17 327 3.6E-60 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS07735 0b3563ffc5cca6e624d5cc5a50528f68 345 SUPERFAMILY SSF56601 4 336 2.82E-82 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS07735 0b3563ffc5cca6e624d5cc5a50528f68 345 Gene3D G3DSA:3.40.710.10 1 345 1.9E-87 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 SMART SM00342 164 247 7.1E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Gene3D G3DSA:3.40.50.1980 256 361 2.9E-8 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 SUPERFAMILY SSF51215 20 135 7.72E-8 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Pfam PF01497 Periplasmic binding protein 301 484 1.9E-9 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Pfam PF12833 Helix-turn-helix domain 173 248 7.8E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 SUPERFAMILY SSF46689 149 198 3.27E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 201 243 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Pfam PF02311 AraC-like ligand binding domain 20 132 1.2E-4 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 SUPERFAMILY SSF53807 246 495 5.89E-31 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Gene3D G3DSA:1.10.10.60 163 205 8.1E-12 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 231 247 8.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 216 231 8.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Gene3D G3DSA:2.60.120.280 1 162 2.3E-7 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Gene3D G3DSA:3.40.50.1980 362 511 3.8E-20 T 29-03-2018 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 SUPERFAMILY SSF46689 200 250 9.86E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04550 583df133621ce660f49a8e3bb4f37a36 515 Gene3D G3DSA:1.10.10.60 206 255 2.8E-12 T 29-03-2018 A616_RS16305 a83483e897c77e95651c89cac37ddd27 158 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A616_RS16305 a83483e897c77e95651c89cac37ddd27 158 Gene3D G3DSA:1.10.10.10 1 147 5.9E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16305 a83483e897c77e95651c89cac37ddd27 158 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 134 4.4E-31 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS16305 a83483e897c77e95651c89cac37ddd27 158 SUPERFAMILY SSF46785 9 133 5.88E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16305 a83483e897c77e95651c89cac37ddd27 158 Pfam PF02082 Transcriptional regulator 1 83 7.2E-21 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 Gene3D G3DSA:1.10.10.60 1 37 1.1E-13 T 29-03-2018 A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 SUPERFAMILY SSF46689 2 88 6.16E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.4E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 SUPERFAMILY SSF48498 126 192 2.0E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 Gene3D G3DSA:1.10.260.40 38 67 3.3E-13 T 29-03-2018 A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 Gene3D G3DSA:1.10.357.10 68 196 2.5E-18 T 29-03-2018 A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS12040 bf2d3bef10b5bc3736afdd8780c098ad 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS12270 ab72294cd1d0537f59d70f357913c6fb 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 3.2E-58 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A616_RS12270 ab72294cd1d0537f59d70f357913c6fb 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 1.1E-20 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A616_RS20170 042e5affbd53b34a83f6d9ef7db79906 109 Gene3D G3DSA:3.40.50.2300 2 40 4.8E-8 T 29-03-2018 A616_RS20170 042e5affbd53b34a83f6d9ef7db79906 109 SUPERFAMILY SSF52788 1 106 3.27E-16 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS20170 042e5affbd53b34a83f6d9ef7db79906 109 Gene3D G3DSA:3.40.50.2300 41 98 0.013 T 29-03-2018 A616_RS20170 042e5affbd53b34a83f6d9ef7db79906 109 SMART SM00226 1 107 0.008 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS20170 042e5affbd53b34a83f6d9ef7db79906 109 PIRSF PIRSF029416 1 108 1.5E-38 T 29-03-2018 IPR016919 Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 Gene3D G3DSA:3.30.1140.32 107 207 4.2E-35 T 29-03-2018 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 SUPERFAMILY SSF54821 106 205 2.49E-37 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 Pfam PF07650 KH domain 37 109 8.6E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.112 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 SUPERFAMILY SSF54814 2 105 4.71E-37 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 Gene3D G3DSA:3.30.300.20 17 106 5.3E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS01430 385937d58de1b5d27458c361a212afaa 220 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 4.4E-38 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 2.4E-94 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A616_RS01430 385937d58de1b5d27458c361a212afaa 220 SMART SM00322 59 124 4.7E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 Gene3D G3DSA:1.10.287.130 249 319 2.6E-13 T 29-03-2018 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 SMART SM00388 258 324 2.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 SUPERFAMILY SSF158472 199 247 3.53E-10 T 29-03-2018 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 SUPERFAMILY SSF55874 327 476 6.16E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 4.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 4.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 4.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 477 4.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 315 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 Gene3D G3DSA:3.30.565.10 336 478 1.1E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 Pfam PF00672 HAMP domain 203 243 5.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 SMART SM00304 198 250 1.4E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 476 6.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 SMART SM00387 366 478 6.3E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16105 95870ef1153d7e02e0c1016a3daed1fa 478 SUPERFAMILY SSF47384 241 318 1.86E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 Pfam PF00183 Hsp90 protein 184 228 9.2E-7 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 Pfam PF00183 Hsp90 protein 217 625 1.1E-108 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 90 107 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 165 182 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 72 89 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 115 137 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 188 206 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 23 45 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PRINTS PR00775 90kDa heat shock protein signature 2 22 1.2E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 SUPERFAMILY SSF54211 236 488 1.52E-80 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 626 26.364 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 151 3.8E-13 T 29-03-2018 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 SUPERFAMILY SSF110942 511 625 5.89E-28 T 29-03-2018 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 Gene3D G3DSA:3.30.565.10 26 220 9.5E-53 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 PIRSF PIRSF002583 1 626 9.6E-200 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 SUPERFAMILY SSF55874 1 212 3.29E-61 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS08510 90311c6be9a31dd2e2ab28db1a3902c5 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 A616_RS04370 c32ef20d57f88aa4981bd15951ba5695 434 Gene3D G3DSA:1.20.1250.20 206 421 8.8E-14 T 29-03-2018 A616_RS04370 c32ef20d57f88aa4981bd15951ba5695 434 SUPERFAMILY SSF103473 9 418 4.84E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS04370 c32ef20d57f88aa4981bd15951ba5695 434 Pfam PF07690 Major Facilitator Superfamily 14 240 6.9E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS04370 c32ef20d57f88aa4981bd15951ba5695 434 Gene3D G3DSA:1.20.1250.20 4 205 1.7E-24 T 29-03-2018 A616_RS25380 de594d2f08e8a46929d7002deb8872fd 156 Pfam PF00583 Acetyltransferase (GNAT) family 32 124 3.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25380 de594d2f08e8a46929d7002deb8872fd 156 Gene3D G3DSA:3.40.630.30 1 156 1.8E-27 T 29-03-2018 A616_RS25380 de594d2f08e8a46929d7002deb8872fd 156 PIRSF PIRSF037663 1 156 2.9E-73 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted A616_RS25380 de594d2f08e8a46929d7002deb8872fd 156 SUPERFAMILY SSF55729 1 155 2.03E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS13295 b51cebd06c1151649901977de0f51610 138 ProSitePatterns PS00934 Glyoxalase I signature 1. 9 30 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A616_RS13295 b51cebd06c1151649901977de0f51610 138 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 114 4.5E-22 T 29-03-2018 A616_RS13295 b51cebd06c1151649901977de0f51610 138 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 6 133 8.1E-45 T 29-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A616_RS13295 b51cebd06c1151649901977de0f51610 138 SUPERFAMILY SSF54593 5 136 1.75E-33 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS13295 b51cebd06c1151649901977de0f51610 138 Gene3D G3DSA:3.10.180.10 2 138 2.4E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 Gene3D G3DSA:1.10.10.10 149 219 4.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 SUPERFAMILY SSF51206 40 148 1.7E-22 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 Pfam PF00027 Cyclic nucleotide-binding domain 41 120 6.6E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 Gene3D G3DSA:2.60.120.10 30 148 4.5E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 Pfam PF13545 Crp-like helix-turn-helix domain 152 217 5.9E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 SMART SM00419 165 211 5.6E-4 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS31205 fc7f58c35ef3c980e16cd8f3bdf6c4ed 223 SUPERFAMILY SSF46785 150 217 3.02E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 Gene3D G3DSA:1.10.1240.30 4 81 6.5E-22 T 29-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 SUPERFAMILY SSF101215 4 80 1.31E-17 T 29-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 144 332 6.0E-46 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 Gene3D G3DSA:3.60.40.10 83 333 4.4E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 SMART SM00331 117 332 1.2E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 SUPERFAMILY SSF81606 130 331 1.57E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 8 80 2.1E-24 T 29-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 A616_RS02900 34dd9503150adc8be091eb3e16b0a33e 333 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 4 87 1.0E-10 T 29-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 A616_RS30020 05aa79785f9f564848a54ccb48f246b5 186 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 9 186 20.429 T 29-03-2018 IPR022929 Putative manganese efflux pump MntP A616_RS30020 05aa79785f9f564848a54ccb48f246b5 186 Pfam PF02659 Putative manganese efflux pump 37 185 3.7E-40 T 29-03-2018 IPR003810 Putative manganese efflux pump A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 Gene3D G3DSA:3.20.20.140 97 504 7.8E-40 T 29-03-2018 A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 Pfam PF07969 Amidohydrolase family 78 567 6.5E-92 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 SUPERFAMILY SSF51338 25 90 1.12E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 SUPERFAMILY SSF51338 526 568 1.12E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 Gene3D G3DSA:2.30.40.10 28 96 1.6E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 SUPERFAMILY SSF51556 226 527 4.0E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 SUPERFAMILY SSF51556 89 150 4.0E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS04475 c7c2d5ae19d9ad8a9c4bd50705a951ab 573 Gene3D G3DSA:2.30.40.10 505 572 4.5E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS31590 d82c57e809a895e95dbfd0cc80705e0a 363 Pfam PF13343 Bacterial extracellular solute-binding protein 96 312 1.3E-29 T 29-03-2018 A616_RS31590 d82c57e809a895e95dbfd0cc80705e0a 363 Gene3D G3DSA:3.40.190.10 29 163 4.5E-12 T 29-03-2018 A616_RS31590 d82c57e809a895e95dbfd0cc80705e0a 363 Gene3D G3DSA:3.40.190.10 164 317 5.9E-34 T 29-03-2018 A616_RS31590 d82c57e809a895e95dbfd0cc80705e0a 363 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 28 360 4.6E-138 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative A616_RS31590 d82c57e809a895e95dbfd0cc80705e0a 363 PIRSF PIRSF002825 2 356 9.5E-89 T 29-03-2018 IPR026045 Ferric binding protein A616_RS31590 d82c57e809a895e95dbfd0cc80705e0a 363 SUPERFAMILY SSF53850 45 353 1.04E-65 T 29-03-2018 A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 Pfam PF00825 Ribonuclease P 1 108 3.9E-34 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 Gene3D G3DSA:3.30.230.10 1 116 4.1E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 19.878 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 110 1.1E-29 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 SUPERFAMILY SSF54211 2 112 2.25E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS32305 db340666c3cf934ed73e796955ff7da6 126 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 108 6.0E-28 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 Gene3D G3DSA:3.10.180.10 223 281 0.23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 123 2.8E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 169 279 3.9E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 SUPERFAMILY SSF54593 7 168 1.88E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 Gene3D G3DSA:3.10.180.10 62 222 2.7E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 Gene3D G3DSA:3.10.180.10 4 61 0.0016 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15435 e98e89f36b8a05c9fe715646b389855d 282 SUPERFAMILY SSF54593 169 281 7.65E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 PRINTS PR00723 Subtilisin serine protease family (S8) signature 140 159 1.4E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 PRINTS PR00723 Subtilisin serine protease family (S8) signature 362 378 1.4E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 PRINTS PR00723 Subtilisin serine protease family (S8) signature 183 196 1.4E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 145 156 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 Gene3D G3DSA:3.40.50.200 76 426 3.3E-76 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 SUPERFAMILY SSF52743 119 422 4.19E-74 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 Pfam PF00082 Subtilase family 140 409 6.2E-45 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 187 197 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A616_RS11705 512490ee6f9bdecc0a45be0deed58f82 429 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 363 373 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A616_RS04580 b653fb18efebdd75c317d294fe5cb385 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 5.3E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS04580 b653fb18efebdd75c317d294fe5cb385 145 SUPERFAMILY SSF54593 1 120 2.42E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS04580 b653fb18efebdd75c317d294fe5cb385 145 Gene3D G3DSA:3.10.180.10 1 133 4.6E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS21615 763468d4c17782eba5d6f5d3dedd5388 142 Pfam PF08968 Domain of unknown function (DUF1885) 4 139 1.1E-59 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 A616_RS21615 763468d4c17782eba5d6f5d3dedd5388 142 Gene3D G3DSA:3.30.310.120 53 137 6.2E-34 T 29-03-2018 A616_RS21615 763468d4c17782eba5d6f5d3dedd5388 142 Gene3D G3DSA:1.20.5.850 5 51 1.4E-22 T 29-03-2018 A616_RS21615 763468d4c17782eba5d6f5d3dedd5388 142 SUPERFAMILY SSF111171 7 137 2.09E-34 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 A616_RS27440 2b061e1c8b31c0a76da4a073d52d8003 322 Pfam PF05138 Phenylacetic acid catabolic protein 29 309 2.9E-79 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 A616_RS27440 2b061e1c8b31c0a76da4a073d52d8003 322 SUPERFAMILY SSF47240 39 287 7.5E-66 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS27440 2b061e1c8b31c0a76da4a073d52d8003 322 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 19 313 7.2E-136 T 29-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 A616_RS27440 2b061e1c8b31c0a76da4a073d52d8003 322 Gene3D G3DSA:1.10.620.20 10 312 4.6E-68 T 29-03-2018 A616_RS13000 9511ae788824f272a0fc2535e5e5617d 356 SUPERFAMILY SSF53092 1 127 2.44E-26 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A616_RS13000 9511ae788824f272a0fc2535e5e5617d 356 Pfam PF00557 Metallopeptidase family M24 137 338 6.3E-66 T 29-03-2018 IPR000994 Peptidase M24 A616_RS13000 9511ae788824f272a0fc2535e5e5617d 356 SUPERFAMILY SSF55920 128 354 3.66E-76 T 29-03-2018 IPR000994 Peptidase M24 A616_RS13000 9511ae788824f272a0fc2535e5e5617d 356 Gene3D G3DSA:3.40.350.10 1 126 7.0E-32 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A616_RS13000 9511ae788824f272a0fc2535e5e5617d 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 8.7E-27 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A616_RS13000 9511ae788824f272a0fc2535e5e5617d 356 Gene3D G3DSA:3.90.230.10 127 354 1.2E-75 T 29-03-2018 A616_RS29560 2f7d1b687b0bc4a194ccec82077a498d 138 Gene3D G3DSA:2.30.290.10 3 138 1.1E-40 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain A616_RS29560 2f7d1b687b0bc4a194ccec82077a498d 138 Pfam PF02623 FliW protein 13 129 1.8E-37 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 A616_RS29560 2f7d1b687b0bc4a194ccec82077a498d 138 SUPERFAMILY SSF141457 11 132 2.88E-36 T 29-03-2018 IPR024046 Flagellar assembly factor FliW domain A616_RS29560 2f7d1b687b0bc4a194ccec82077a498d 138 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 10 132 24.029 T 29-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 A616_RS15885 f32c5faa86ed33bd919e95370ee3c6eb 76 SUPERFAMILY SSF140500 26 70 1.44E-10 T 29-03-2018 A616_RS15885 f32c5faa86ed33bd919e95370ee3c6eb 76 Pfam PF09388 Spo0E like sporulation regulatory protein 27 68 1.3E-13 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 Gene3D G3DSA:3.90.180.10 1 155 4.1E-51 T 29-03-2018 A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 Gene3D G3DSA:3.40.50.10730 156 290 5.7E-36 T 29-03-2018 A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 55 69 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 SUPERFAMILY SSF50129 1 166 2.28E-49 T 29-03-2018 IPR011032 GroES-like A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 SUPERFAMILY SSF51735 134 308 6.4E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 SMART SM00829 5 338 1.9E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 Pfam PF00107 Zinc-binding dehydrogenase 172 299 2.2E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS15585 c52af97fb8faaf3cf5351b98a5f7be98 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 127 2.1E-31 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 Hamap MF_00008 Thymidylate synthase [thyA]. 5 277 33.539 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 PRINTS PR00108 Thymidylate synthase family signature 128 147 1.0E-20 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 1.0E-20 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 PRINTS PR00108 Thymidylate synthase family signature 54 75 1.0E-20 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 PRINTS PR00108 Thymidylate synthase family signature 154 169 1.0E-20 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 1.0E-20 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 Pfam PF00303 Thymidylate synthase 7 277 6.6E-81 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 Gene3D G3DSA:3.30.572.10 1 277 3.2E-85 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 100 277 6.8E-41 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS16495 6cae0368efd7ea61bda73600d3ac7269 277 SUPERFAMILY SSF55831 3 277 7.2E-84 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A616_RS21780 01694d4732e317a87734a0f59691464c 269 Pfam PF13280 WYL domain 85 260 6.6E-12 T 29-03-2018 IPR026881 WYL domain A616_RS10790 fc7fbed31bf5944fa8da763120475483 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A616_RS10790 fc7fbed31bf5944fa8da763120475483 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 5.7E-33 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS10790 fc7fbed31bf5944fa8da763120475483 139 Pfam PF02082 Transcriptional regulator 2 82 2.8E-27 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS10790 fc7fbed31bf5944fa8da763120475483 139 Gene3D G3DSA:1.10.10.10 1 139 1.9E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10790 fc7fbed31bf5944fa8da763120475483 139 SUPERFAMILY SSF46785 2 125 8.16E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 SMART SM00304 178 232 5.8E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 SUPERFAMILY SSF47384 218 296 4.51E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 SMART SM00387 342 452 1.9E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 449 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 1.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 SMART SM00388 233 300 1.3E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 SUPERFAMILY SSF55874 294 449 4.45E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 SUPERFAMILY SSF158472 179 229 8.37E-5 T 29-03-2018 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 Gene3D G3DSA:1.10.287.130 223 295 6.7E-15 T 29-03-2018 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 296 1.8E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 449 1.8E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS28170 6167939ec32073e21da737c9e2d246fc 454 Gene3D G3DSA:3.30.565.10 303 454 8.4E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03360 40d32944b1b558d33ade9fd4d9873220 607 Gene3D G3DSA:3.20.20.370 264 577 2.9E-13 T 29-03-2018 A616_RS03360 40d32944b1b558d33ade9fd4d9873220 607 Pfam PF09960 Uncharacterised protein conserved in bacteria (DUF2194) 12 180 2.9E-28 T 29-03-2018 IPR018695 Protein of unknown function DUF2194 A616_RS03360 40d32944b1b558d33ade9fd4d9873220 607 Pfam PF09960 Uncharacterised protein conserved in bacteria (DUF2194) 205 593 3.6E-147 T 29-03-2018 IPR018695 Protein of unknown function DUF2194 A616_RS03360 40d32944b1b558d33ade9fd4d9873220 607 Gene3D G3DSA:3.40.50.880 58 255 0.0032 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS27475 26d400164447eb6d35a17078db23e3f9 275 Pfam PF07848 PaaX-like protein 3 71 5.3E-26 T 29-03-2018 IPR012906 PaaX-like, N-terminal A616_RS27475 26d400164447eb6d35a17078db23e3f9 275 Pfam PF08223 PaaX-like protein C-terminal domain 166 266 1.4E-31 T 29-03-2018 IPR013225 PaaX-like, C-terminal A616_RS27475 26d400164447eb6d35a17078db23e3f9 275 SUPERFAMILY SSF46785 28 141 1.26E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27475 26d400164447eb6d35a17078db23e3f9 275 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 5 270 1.1E-88 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A616_RS27475 26d400164447eb6d35a17078db23e3f9 275 Gene3D G3DSA:1.10.10.10 1 84 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27475 26d400164447eb6d35a17078db23e3f9 275 PIRSF PIRSF020623 1 275 7.2E-97 T 29-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 A616_RS25355 8448a04f64c10031f5c9088aa7e0a689 145 Gene3D G3DSA:2.60.40.1310 16 145 2.4E-4 T 29-03-2018 A616_RS05205 85c4edbb1c78fa995c2e08b48abc56ec 261 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 257 16.605 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A616_RS05205 85c4edbb1c78fa995c2e08b48abc56ec 261 Pfam PF02673 Bacitracin resistance protein BacA 10 251 1.7E-72 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 SMART SM00304 333 385 3.3E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 Gene3D G3DSA:3.30.450.20 189 302 8.5E-16 T 29-03-2018 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 483 641 6.7E-40 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 Gene3D G3DSA:1.10.287.950 359 458 3.7E-5 T 29-03-2018 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 Gene3D G3DSA:1.10.287.950 459 690 3.0E-45 T 29-03-2018 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 Gene3D G3DSA:3.30.450.20 66 188 1.1E-6 T 29-03-2018 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 SMART SM00283 414 689 3.4E-58 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 Pfam PF02743 Cache domain 74 295 1.7E-21 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 SUPERFAMILY SSF58104 420 688 1.02E-65 T 29-03-2018 A616_RS13390 a99e92fd8affaf6fc69581efc172f4a3 690 SUPERFAMILY SSF58104 355 387 1.02E-65 T 29-03-2018 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 254 2.3E-108 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 SUPERFAMILY SSF53790 2 233 1.44E-70 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 1.6E-50 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 Gene3D G3DSA:3.30.950.10 122 245 3.9E-28 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 Gene3D G3DSA:3.40.1010.10 1 121 8.6E-37 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07355 ac8caef4b664ba6c488d8775fb8c230f 259 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS16250 8e6d9270d875e61823d57a4b738b04d0 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS16250 8e6d9270d875e61823d57a4b738b04d0 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS16250 8e6d9270d875e61823d57a4b738b04d0 203 SUPERFAMILY SSF46689 3 65 1.49E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS16250 8e6d9270d875e61823d57a4b738b04d0 203 Gene3D G3DSA:1.10.10.60 47 191 1.9E-7 T 29-03-2018 A616_RS16250 8e6d9270d875e61823d57a4b738b04d0 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 3.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS16250 8e6d9270d875e61823d57a4b738b04d0 203 Gene3D G3DSA:1.10.10.60 2 46 3.4E-14 T 29-03-2018 A616_RS07730 df9aaa2d706076c71913d159acef0695 288 Gene3D G3DSA:3.40.50.10490 83 277 2.9E-36 T 29-03-2018 A616_RS07730 df9aaa2d706076c71913d159acef0695 288 Pfam PF01380 SIS domain 131 259 2.6E-21 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS07730 df9aaa2d706076c71913d159acef0695 288 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 81 1.9E-23 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A616_RS07730 df9aaa2d706076c71913d159acef0695 288 SUPERFAMILY SSF53697 101 276 3.12E-38 T 29-03-2018 A616_RS07730 df9aaa2d706076c71913d159acef0695 288 SUPERFAMILY SSF46689 10 82 2.69E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS07730 df9aaa2d706076c71913d159acef0695 288 Gene3D G3DSA:1.10.10.10 5 82 3.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14135 43f23ec228335590d8bf5e91cceb2cb8 302 Pfam PF00849 RNA pseudouridylate synthase 94 245 2.6E-34 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS14135 43f23ec228335590d8bf5e91cceb2cb8 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 27 302 2.4E-76 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS14135 43f23ec228335590d8bf5e91cceb2cb8 302 SUPERFAMILY SSF55120 87 301 6.72E-71 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A616_RS14135 43f23ec228335590d8bf5e91cceb2cb8 302 Gene3D G3DSA:3.30.2350.10 85 302 5.9E-69 T 29-03-2018 A616_RS25765 793bf75443951fece07542d6735f794a 411 Pfam PF03594 Benzoate membrane transport protein 16 391 2.6E-147 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 A616_RS25765 793bf75443951fece07542d6735f794a 411 TIGRFAM TIGR00843 benE: benzoate transporter 18 393 6.4E-129 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 SMART SM00387 319 431 1.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 428 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 1.9E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 Gene3D G3DSA:3.30.565.10 174 430 1.4E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 429 7.0E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS15170 338921625dddf1c1f97061f3b000e67b 436 SUPERFAMILY SSF55874 281 429 7.33E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23670 125cc4d21d545e75918406bb5a558259 183 SUPERFAMILY SSF88659 104 175 4.91E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23670 125cc4d21d545e75918406bb5a558259 183 Gene3D G3DSA:1.10.1740.10 4 95 1.6E-14 T 29-03-2018 A616_RS23670 125cc4d21d545e75918406bb5a558259 183 Pfam PF08281 Sigma-70, region 4 122 170 1.1E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23670 125cc4d21d545e75918406bb5a558259 183 SUPERFAMILY SSF88946 9 105 7.06E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23670 125cc4d21d545e75918406bb5a558259 183 Pfam PF04542 Sigma-70 region 2 25 91 2.0E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23670 125cc4d21d545e75918406bb5a558259 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 172 2.0E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS23670 125cc4d21d545e75918406bb5a558259 183 Gene3D G3DSA:1.10.10.10 96 176 9.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12930 8ed65bd116adb4ec624c7dabd79b1ae4 450 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 49.965 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A616_RS12930 8ed65bd116adb4ec624c7dabd79b1ae4 450 SUPERFAMILY SSF53383 3 447 1.88E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS12930 8ed65bd116adb4ec624c7dabd79b1ae4 450 Gene3D G3DSA:3.90.1150.10 338 449 4.1E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12930 8ed65bd116adb4ec624c7dabd79b1ae4 450 PIRSF PIRSF006815 3 448 4.3E-191 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A616_RS12930 8ed65bd116adb4ec624c7dabd79b1ae4 450 Gene3D G3DSA:3.40.640.10 84 337 8.5E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS12930 8ed65bd116adb4ec624c7dabd79b1ae4 450 Pfam PF02347 Glycine cleavage system P-protein 4 442 8.4E-153 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 Pfam PF13353 4Fe-4S single cluster domain 126 197 1.3E-4 T 29-03-2018 A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 PIRSF PIRSF004911 1 398 1.3E-164 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 339 1.7E-142 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 Pfam PF12544 Lysine-2,3-aminomutase 320 442 2.9E-50 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 SUPERFAMILY SSF102114 113 356 2.62E-33 T 29-03-2018 A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 20 421 5.7E-194 T 29-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 A616_RS30190 8bc0687dd65df1a6ef5f42ac7e8ad59c 454 Gene3D G3DSA:3.20.20.70 116 324 1.5E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS11845 8c946090fe6c44901e20ffc0e0a4b44e 685 Pfam PF07075 Protein of unknown function (DUF1343) 49 394 2.0E-104 T 29-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 A616_RS11845 8c946090fe6c44901e20ffc0e0a4b44e 685 SUPERFAMILY SSF88713 462 671 4.23E-51 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS11845 8c946090fe6c44901e20ffc0e0a4b44e 685 Pfam PF01522 Polysaccharide deacetylase 467 578 5.2E-31 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS11845 8c946090fe6c44901e20ffc0e0a4b44e 685 Gene3D G3DSA:3.20.20.370 449 675 6.1E-52 T 29-03-2018 A616_RS20055 4893c4a4b553eba4c7322192934dddc4 137 PIRSF PIRSF002889 2 135 7.7E-28 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A616_RS20055 4893c4a4b553eba4c7322192934dddc4 137 Pfam PF00460 Flagella basal body rod protein 7 37 5.6E-5 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A616_RS20055 4893c4a4b553eba4c7322192934dddc4 137 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 133 9.3E-30 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 322 333 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 Gene3D G3DSA:3.30.70.1170 170 236 1.6E-11 T 29-03-2018 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 Pfam PF01029 NusB family 6 127 2.8E-30 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 Gene3D G3DSA:1.10.940.10 1 150 5.4E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 Gene3D G3DSA:3.40.50.150 237 448 4.9E-63 T 29-03-2018 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 447 5.4E-142 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 3.1E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 429 446 3.1E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 3.1E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 3.1E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 3.1E-32 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 SUPERFAMILY SSF53335 140 446 1.98E-75 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 Pfam PF01189 16S rRNA methyltransferase RsmB/F 246 445 2.4E-61 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A616_RS20775 1fa6b22cebdb468460f49f5515ce6c1a 448 SUPERFAMILY SSF48013 6 154 6.02E-36 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 Gene3D G3DSA:3.30.930.10 1 339 1.7E-80 T 29-03-2018 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 PIRSF PIRSF001549 2 431 1.0E-116 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 SUPERFAMILY SSF55681 7 334 2.3E-68 T 29-03-2018 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 Pfam PF13393 Histidyl-tRNA synthetase 11 325 3.5E-44 T 29-03-2018 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 SUPERFAMILY SSF52954 341 431 9.97E-20 T 29-03-2018 IPR004154 Anticodon-binding A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 8 419 3.9E-106 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 429 24.769 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 Gene3D G3DSA:3.40.50.800 340 433 1.2E-18 T 29-03-2018 IPR004154 Anticodon-binding A616_RS03190 ee81fa64d4b04e5acba8c33351c5eb51 433 Pfam PF03129 Anticodon binding domain 342 429 6.8E-15 T 29-03-2018 IPR004154 Anticodon-binding A616_RS16065 d28d7e3d05597696447ba1f125005479 206 Pfam PF00583 Acetyltransferase (GNAT) family 57 178 1.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS16065 d28d7e3d05597696447ba1f125005479 206 SUPERFAMILY SSF55729 41 181 2.78E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS16065 d28d7e3d05597696447ba1f125005479 206 Gene3D G3DSA:3.40.630.30 6 206 8.7E-23 T 29-03-2018 A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 4.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 4.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 4.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 Pfam PF00106 short chain dehydrogenase 7 207 5.7E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 Gene3D G3DSA:3.40.50.720 1 264 1.3E-35 T 29-03-2018 A616_RS25770 3c85aeaae1867f5cbe0308f5cf130a8f 291 SUPERFAMILY SSF51735 3 260 1.04E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26590 1e9ecc1e8187a1e495a77990532dca03 241 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 21 221 4.8E-55 T 29-03-2018 IPR014197 Sporulation protein YunB A616_RS26590 1e9ecc1e8187a1e495a77990532dca03 241 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 130 218 3.0E-30 T 29-03-2018 IPR014197 Sporulation protein YunB A616_RS26590 1e9ecc1e8187a1e495a77990532dca03 241 PIRSF PIRSF021383 6 235 1.4E-52 T 29-03-2018 IPR014197 Sporulation protein YunB A616_RS28140 c43d042e8da0173eb0f745ccf8233fb7 185 SUPERFAMILY SSF48150 1 183 6.51E-82 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A616_RS28140 c43d042e8da0173eb0f745ccf8233fb7 185 Gene3D G3DSA:1.10.340.30 1 182 1.6E-85 T 29-03-2018 A616_RS28140 c43d042e8da0173eb0f745ccf8233fb7 185 Pfam PF03352 Methyladenine glycosylase 6 179 1.5E-83 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A616_RS28140 c43d042e8da0173eb0f745ccf8233fb7 185 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 3 182 2.9E-76 T 29-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 A616_RS23890 eac7c50c0a9c65826a9a7e5aec376e54 360 Gene3D G3DSA:1.50.10.10 2 304 1.2E-62 T 29-03-2018 A616_RS23890 eac7c50c0a9c65826a9a7e5aec376e54 360 Gene3D G3DSA:1.50.10.10 305 359 1.9E-7 T 29-03-2018 A616_RS23890 eac7c50c0a9c65826a9a7e5aec376e54 360 SUPERFAMILY SSF48208 14 356 7.78E-68 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A616_RS23890 eac7c50c0a9c65826a9a7e5aec376e54 360 Pfam PF00723 Glycosyl hydrolases family 15 9 310 3.3E-21 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 296 2.6E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 316 1.6E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 Gene3D G3DSA:3.40.50.300 2 318 2.7E-80 T 29-03-2018 A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 Pfam PF00005 ABC transporter 27 176 1.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 SMART SM00382 35 227 4.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15865 2b557fb2afda2166522d77b82f334e0b 318 SUPERFAMILY SSF52540 6 249 1.08E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02705 ddbaa2fb079526a38bc1fa76d0112f7c 549 PIRSF PIRSF002741 2 547 5.8E-124 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS02705 ddbaa2fb079526a38bc1fa76d0112f7c 549 Gene3D G3DSA:3.10.105.10 323 520 6.4E-51 T 29-03-2018 A616_RS02705 ddbaa2fb079526a38bc1fa76d0112f7c 549 Gene3D G3DSA:3.40.190.10 186 322 1.1E-42 T 29-03-2018 A616_RS02705 ddbaa2fb079526a38bc1fa76d0112f7c 549 Gene3D G3DSA:3.90.76.10 75 185 1.2E-30 T 29-03-2018 A616_RS02705 ddbaa2fb079526a38bc1fa76d0112f7c 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 470 3.5E-81 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS02705 ddbaa2fb079526a38bc1fa76d0112f7c 549 SUPERFAMILY SSF53850 46 542 7.96E-129 T 29-03-2018 A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 SMART SM00267 232 401 7.1E-45 T 29-03-2018 IPR000160 GGDEF domain A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 Gene3D G3DSA:3.30.450.40 64 239 1.3E-19 T 29-03-2018 IPR029016 GAF domain-like A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 Pfam PF13492 GAF domain 95 231 7.1E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 SMART SM00065 92 240 8.0E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 Gene3D G3DSA:3.30.70.270 240 403 5.5E-49 T 29-03-2018 A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 Pfam PF00990 Diguanylate cyclase, GGDEF domain 244 396 9.1E-36 T 29-03-2018 IPR000160 GGDEF domain A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 241 400 3.3E-35 T 29-03-2018 IPR000160 GGDEF domain A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 SUPERFAMILY SSF55781 75 245 1.31E-22 T 29-03-2018 IPR029016 GAF domain-like A616_RS07770 59726622547bb4fb208a0d9d7cf86fc7 404 SUPERFAMILY SSF55073 248 401 2.75E-42 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS26510 8409d643de1d37208e84dff4327884c8 510 Gene3D G3DSA:3.40.605.10 3 251 2.3E-84 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS26510 8409d643de1d37208e84dff4327884c8 510 Gene3D G3DSA:3.40.309.10 252 441 4.5E-72 T 29-03-2018 A616_RS26510 8409d643de1d37208e84dff4327884c8 510 Pfam PF00171 Aldehyde dehydrogenase family 6 453 3.3E-147 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS26510 8409d643de1d37208e84dff4327884c8 510 SUPERFAMILY SSF53720 6 456 1.83E-151 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS26510 8409d643de1d37208e84dff4327884c8 510 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 233 240 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A616_RS26510 8409d643de1d37208e84dff4327884c8 510 PIRSF PIRSF036492 13 497 3.1E-124 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 Gene3D G3DSA:2.30.40.10 1 63 6.5E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 Gene3D G3DSA:3.20.20.140 64 278 2.7E-57 T 29-03-2018 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 Gene3D G3DSA:3.20.20.140 279 424 2.9E-41 T 29-03-2018 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 SUPERFAMILY SSF51338 342 459 4.61E-39 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 3 455 1.3E-211 T 29-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 SUPERFAMILY SSF51556 53 383 3.63E-111 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 SUPERFAMILY SSF51338 2 65 6.48E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18720 1542a18b661d143b17e52666923b6bd3 461 Pfam PF01979 Amidohydrolase family 49 436 9.9E-28 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS11090 71eb0333715d8413efa4c030f0ec71fd 156 Pfam PF00085 Thioredoxin 64 152 1.8E-14 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 A616_RS11090 71eb0333715d8413efa4c030f0ec71fd 156 Gene3D G3DSA:3.40.30.10 53 156 4.3E-17 T 29-03-2018 A616_RS11090 71eb0333715d8413efa4c030f0ec71fd 156 SUPERFAMILY SSF52833 55 151 7.79E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS09945 cd86c0d802fed74f99c807613bb19c5d 328 SUPERFAMILY SSF53067 7 317 5.56E-65 T 29-03-2018 A616_RS09945 cd86c0d802fed74f99c807613bb19c5d 328 Pfam PF00480 ROK family 9 316 7.8E-71 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS09945 cd86c0d802fed74f99c807613bb19c5d 328 ProSitePatterns PS01125 ROK family signature. 141 168 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS09945 cd86c0d802fed74f99c807613bb19c5d 328 Gene3D G3DSA:3.30.420.40 127 324 3.8E-57 T 29-03-2018 A616_RS09945 cd86c0d802fed74f99c807613bb19c5d 328 Gene3D G3DSA:3.30.420.40 1 126 2.6E-35 T 29-03-2018 A616_RS27160 e5d63c9d0a4d7d81610d1b4f89056d9d 254 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 32 237 1.0E-51 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 A616_RS27160 e5d63c9d0a4d7d81610d1b4f89056d9d 254 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 31 238 1.1E-88 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 A616_RS27160 e5d63c9d0a4d7d81610d1b4f89056d9d 254 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 31 246 29.531 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 A616_RS07345 88080af6ef916ca67b448cd018285898 409 Gene3D G3DSA:3.40.1010.10 4 110 3.6E-8 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07345 88080af6ef916ca67b448cd018285898 409 Gene3D G3DSA:3.30.950.10 111 207 2.6E-29 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07345 88080af6ef916ca67b448cd018285898 409 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 7 198 2.5E-57 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 A616_RS07345 88080af6ef916ca67b448cd018285898 409 Pfam PF12847 Methyltransferase domain 234 338 1.3E-6 T 29-03-2018 A616_RS07345 88080af6ef916ca67b448cd018285898 409 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 185 6.1E-16 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07345 88080af6ef916ca67b448cd018285898 409 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 228 348 9.0E-36 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 A616_RS07345 88080af6ef916ca67b448cd018285898 409 SUPERFAMILY SSF53335 210 365 8.52E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS07345 88080af6ef916ca67b448cd018285898 409 SUPERFAMILY SSF53790 6 201 7.33E-32 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07345 88080af6ef916ca67b448cd018285898 409 Gene3D G3DSA:3.40.50.150 210 407 2.4E-27 T 29-03-2018 A616_RS07345 88080af6ef916ca67b448cd018285898 409 PIRSF PIRSF036428 1 400 4.5E-118 T 29-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 A616_RS04000 bd372c7ba61640596b813d071336ee62 306 Gene3D G3DSA:3.30.450.20 10 136 6.3E-11 T 29-03-2018 A616_RS04000 bd372c7ba61640596b813d071336ee62 306 Gene3D G3DSA:3.30.70.270 137 306 3.7E-63 T 29-03-2018 A616_RS04000 bd372c7ba61640596b813d071336ee62 306 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 138 302 5.7E-49 T 29-03-2018 IPR000160 GGDEF domain A616_RS04000 bd372c7ba61640596b813d071336ee62 306 SUPERFAMILY SSF55785 45 138 5.48E-8 T 29-03-2018 IPR000014 PAS domain A616_RS04000 bd372c7ba61640596b813d071336ee62 306 SMART SM00267 131 303 5.2E-73 T 29-03-2018 IPR000160 GGDEF domain A616_RS04000 bd372c7ba61640596b813d071336ee62 306 Pfam PF00990 Diguanylate cyclase, GGDEF domain 142 299 1.6E-54 T 29-03-2018 IPR000160 GGDEF domain A616_RS04000 bd372c7ba61640596b813d071336ee62 306 SUPERFAMILY SSF55073 147 304 2.9E-52 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS04000 bd372c7ba61640596b813d071336ee62 306 Pfam PF08448 PAS fold 43 132 1.5E-9 T 29-03-2018 IPR013656 PAS fold-4 A616_RS21895 64546ec702c762142af78af78a3cf743 413 Gene3D G3DSA:1.10.10.60 352 413 1.5E-15 T 29-03-2018 A616_RS21895 64546ec702c762142af78af78a3cf743 413 SMART SM00382 127 275 5.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS21895 64546ec702c762142af78af78a3cf743 413 SUPERFAMILY SSF46689 321 412 6.15E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS21895 64546ec702c762142af78af78a3cf743 413 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 194 209 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A616_RS21895 64546ec702c762142af78af78a3cf743 413 Pfam PF02954 Bacterial regulatory protein, Fis family 371 410 1.7E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS21895 64546ec702c762142af78af78a3cf743 413 Gene3D G3DSA:1.10.8.60 280 351 8.9E-22 T 29-03-2018 A616_RS21895 64546ec702c762142af78af78a3cf743 413 Pfam PF00158 Sigma-54 interaction domain 109 274 1.2E-64 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS21895 64546ec702c762142af78af78a3cf743 413 SUPERFAMILY SSF52540 107 351 1.38E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21895 64546ec702c762142af78af78a3cf743 413 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 321 330 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS21895 64546ec702c762142af78af78a3cf743 413 Gene3D G3DSA:3.40.50.300 101 279 1.1E-26 T 29-03-2018 A616_RS01480 ec225978bf530aa2195f8dc15d874dec 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 5.0E-48 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01480 ec225978bf530aa2195f8dc15d874dec 120 Gene3D G3DSA:3.30.420.100 1 120 5.1E-43 T 29-03-2018 A616_RS01480 ec225978bf530aa2195f8dc15d874dec 120 SUPERFAMILY SSF53137 7 118 3.05E-53 T 29-03-2018 A616_RS01480 ec225978bf530aa2195f8dc15d874dec 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 29.742 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01480 ec225978bf530aa2195f8dc15d874dec 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 3.3E-43 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19935 5d53d9e5bd11fe0d20f0986ea9e9f9a3 287 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 24 240 2.7E-13 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A616_RS19935 5d53d9e5bd11fe0d20f0986ea9e9f9a3 287 SUPERFAMILY SSF52540 21 275 4.07E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19935 5d53d9e5bd11fe0d20f0986ea9e9f9a3 287 Gene3D G3DSA:3.40.50.300 20 265 8.2E-48 T 29-03-2018 A616_RS19935 5d53d9e5bd11fe0d20f0986ea9e9f9a3 287 PIRSF PIRSF003092 1 287 2.3E-82 T 29-03-2018 IPR025501 ATP binding protein MinD A616_RS11140 e0160b1e56f4155c17a272a1bc7da27f 286 SUPERFAMILY SSF55729 152 275 3.11E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11140 e0160b1e56f4155c17a272a1bc7da27f 286 Pfam PF00583 Acetyltransferase (GNAT) family 45 120 3.7E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS11140 e0160b1e56f4155c17a272a1bc7da27f 286 Pfam PF00583 Acetyltransferase (GNAT) family 184 273 7.6E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS11140 e0160b1e56f4155c17a272a1bc7da27f 286 Gene3D G3DSA:3.40.630.30 11 153 1.2E-14 T 29-03-2018 A616_RS11140 e0160b1e56f4155c17a272a1bc7da27f 286 SUPERFAMILY SSF55729 15 131 9.66E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11140 e0160b1e56f4155c17a272a1bc7da27f 286 Gene3D G3DSA:3.40.630.30 154 284 4.8E-23 T 29-03-2018 A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 Pfam PF07969 Amidohydrolase family 51 530 6.8E-112 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 Gene3D G3DSA:3.20.20.140 184 487 7.6E-52 T 29-03-2018 A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 SUPERFAMILY SSF51338 489 530 1.18E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 SUPERFAMILY SSF51338 1 62 1.18E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 SUPERFAMILY SSF51556 61 118 1.01E-36 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 SUPERFAMILY SSF51556 196 490 1.01E-36 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS20605 a6bcc8020640405d3cab4c2f99f7b9df 532 Gene3D G3DSA:2.30.40.10 1 119 3.7E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 Pfam PF00005 ABC transporter 287 425 1.3E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 Pfam PF00005 ABC transporter 25 175 9.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 SUPERFAMILY SSF52540 1 254 1.56E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 SUPERFAMILY SSF52540 262 475 1.85E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 SMART SM00382 33 212 3.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 SMART SM00382 295 473 6.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 Gene3D G3DSA:3.40.50.300 269 489 1.3E-48 T 29-03-2018 A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08445 2612158e9119cceb73cf959a8b0ba193 493 Gene3D G3DSA:3.40.50.300 1 262 2.2E-55 T 29-03-2018 A616_RS25560 4ec27a04f33d758d1d2fdb6f04a4e0b2 170 SUPERFAMILY SSF55729 14 169 3.09E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25560 4ec27a04f33d758d1d2fdb6f04a4e0b2 170 Gene3D G3DSA:3.40.630.30 13 170 4.4E-30 T 29-03-2018 A616_RS25560 4ec27a04f33d758d1d2fdb6f04a4e0b2 170 Pfam PF13673 Acetyltransferase (GNAT) domain 51 147 1.0E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS07140 224c2dc87a200ad51f1705c34d9c1ade 175 SUPERFAMILY SSF46785 2 170 7.07E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07140 224c2dc87a200ad51f1705c34d9c1ade 175 Pfam PF03551 Transcriptional regulator PadR-like family 7 82 1.2E-11 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS07140 224c2dc87a200ad51f1705c34d9c1ade 175 Gene3D G3DSA:1.10.10.10 1 94 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09350 e171ca672f60c84ae5f105639afba886 158 Pfam PF07238 PilZ domain 9 116 2.3E-8 T 29-03-2018 IPR009875 PilZ domain GO:0035438 A616_RS09350 e171ca672f60c84ae5f105639afba886 158 Gene3D G3DSA:2.40.10.220 9 121 4.9E-13 T 29-03-2018 A616_RS17470 dc9f6bac932ed3c145ea94c124bb4772 275 Pfam PF02498 BRO family, N-terminal domain 17 103 8.1E-27 T 29-03-2018 IPR003497 BRO N-terminal domain A616_RS17470 dc9f6bac932ed3c145ea94c124bb4772 275 Pfam PF03374 Phage antirepressor protein KilAC domain 147 250 9.7E-26 T 29-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 A616_RS17470 dc9f6bac932ed3c145ea94c124bb4772 275 SMART SM01040 17 103 3.5E-40 T 29-03-2018 IPR003497 BRO N-terminal domain A616_RS05195 8d427bf56837f8ddca015c0401dedb3f 119 Pfam PF01751 Toprim domain 5 76 2.8E-5 T 29-03-2018 IPR006171 TOPRIM domain A616_RS05195 8d427bf56837f8ddca015c0401dedb3f 119 Gene3D G3DSA:3.40.1360.20 2 111 1.3E-12 T 29-03-2018 A616_RS05195 8d427bf56837f8ddca015c0401dedb3f 119 SMART SM00493 3 80 0.0013 T 29-03-2018 IPR006171 TOPRIM domain A616_RS05195 8d427bf56837f8ddca015c0401dedb3f 119 SUPERFAMILY SSF110455 5 109 4.18E-23 T 29-03-2018 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 108 2.6E-12 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 82 108 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 PRINTS PR00046 Major sigma-70 factor signature 61 73 6.1E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 PRINTS PR00046 Major sigma-70 factor signature 82 97 6.1E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 PRINTS PR00046 Major sigma-70 factor signature 97 108 6.1E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 Gene3D G3DSA:1.10.1270.10 28 118 8.6E-23 T 29-03-2018 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 SUPERFAMILY SSF88659 24 108 1.99E-19 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS11010 d6e9c03b5e35a0c3755603d4db8812d9 121 Pfam PF04545 Sigma-70, region 4 60 108 4.0E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS22330 b938cc2418f903258fc4bd1f18f35493 351 SUPERFAMILY SSF53822 65 317 1.06E-15 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS22330 b938cc2418f903258fc4bd1f18f35493 351 Pfam PF04392 ABC transporter substrate binding protein 57 349 5.5E-95 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein A616_RS22330 b938cc2418f903258fc4bd1f18f35493 351 Gene3D G3DSA:3.40.50.2300 54 179 8.0E-22 T 29-03-2018 A616_RS22330 b938cc2418f903258fc4bd1f18f35493 351 Gene3D G3DSA:3.40.50.2300 180 317 6.9E-22 T 29-03-2018 A616_RS02555 cf50256a7e2ef7bde2838da1d1ae012b 252 Gene3D G3DSA:3.40.50.1000 124 252 5.0E-8 T 29-03-2018 IPR023214 HAD-like domain A616_RS02555 cf50256a7e2ef7bde2838da1d1ae012b 252 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 232 1.6E-27 T 29-03-2018 IPR023214 HAD-like domain A616_RS02555 cf50256a7e2ef7bde2838da1d1ae012b 252 Gene3D G3DSA:3.40.50.1000 3 108 1.3E-10 T 29-03-2018 IPR023214 HAD-like domain A616_RS02555 cf50256a7e2ef7bde2838da1d1ae012b 252 SUPERFAMILY SSF56784 3 248 4.51E-32 T 29-03-2018 IPR023214 HAD-like domain A616_RS02555 cf50256a7e2ef7bde2838da1d1ae012b 252 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 215 1.5E-11 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 SMART SM00418 11 89 3.7E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 7.2E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 7.2E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 7.2E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 Gene3D G3DSA:1.10.10.10 3 86 4.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 SUPERFAMILY SSF46785 5 92 1.52E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30510 d2067d35f6df8b24fa9bd70861b3dd0f 108 Pfam PF01022 Bacterial regulatory protein, arsR family 18 62 3.6E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 5.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 5.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 5.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 SMART SM00418 14 94 1.6E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 Pfam PF12840 Helix-turn-helix domain 15 74 7.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 Gene3D G3DSA:1.10.10.10 2 89 1.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05190 73de01c3b02ab1a3409014e8e87d714a 96 SUPERFAMILY SSF46785 7 94 1.09E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27335 2e1a83d26ae618943ec748b205c0af28 146 SUPERFAMILY SSF55961 8 145 2.86E-32 T 29-03-2018 A616_RS27335 2e1a83d26ae618943ec748b205c0af28 146 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 143 5.8E-23 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS27335 2e1a83d26ae618943ec748b205c0af28 146 Gene3D G3DSA:3.30.530.20 1 146 4.0E-22 T 29-03-2018 IPR023393 START-like domain A616_RS13800 7e4de0cb02a8cfb761cb093f8b3ee353 125 Pfam PF07736 Chorismate mutase type I 3 121 9.3E-46 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS13800 7e4de0cb02a8cfb761cb093f8b3ee353 125 Gene3D G3DSA:3.30.1330.40 3 122 2.4E-47 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS13800 7e4de0cb02a8cfb761cb093f8b3ee353 125 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 121 1.0E-30 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS13800 7e4de0cb02a8cfb761cb093f8b3ee353 125 SUPERFAMILY SSF55298 2 122 1.96E-44 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS13800 7e4de0cb02a8cfb761cb093f8b3ee353 125 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 121 1.1E-43 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS13800 7e4de0cb02a8cfb761cb093f8b3ee353 125 PIRSF PIRSF005965 1 125 4.3E-48 T 29-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A616_RS23060 33caa50b5504095805873797fa518414 199 TIGRFAM TIGR04536 geobac_encap: encapsulated protein 2 197 9.0E-92 T 29-03-2018 IPR030909 Encapsulated protein A616_RS23060 33caa50b5504095805873797fa518414 199 Gene3D G3DSA:1.20.1260.10 17 92 6.5E-4 T 29-03-2018 IPR012347 Ferritin-related A616_RS30320 640b770e77d85236f58e67f1beb438b8 370 Pfam PF02073 Thermophilic metalloprotease (M29) 4 333 4.3E-55 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS30320 640b770e77d85236f58e67f1beb438b8 370 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 265 285 6.1E-10 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS30320 640b770e77d85236f58e67f1beb438b8 370 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 210 229 6.1E-10 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS30320 640b770e77d85236f58e67f1beb438b8 370 Gene3D G3DSA:3.40.1830.10 2 163 1.8E-37 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS30320 640b770e77d85236f58e67f1beb438b8 370 SUPERFAMILY SSF144052 1 356 4.32E-99 T 29-03-2018 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 SUPERFAMILY SSF53850 90 294 1.81E-44 T 29-03-2018 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 Gene3D G3DSA:3.40.190.10 176 264 1.8E-23 T 29-03-2018 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 Pfam PF03466 LysR substrate binding domain 89 289 3.0E-46 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 SUPERFAMILY SSF46785 1 86 2.26E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.5E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 Gene3D G3DSA:1.10.10.10 1 91 5.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04930 3f462ac2fa50e57d29ebe1ec1a7e98ab 298 Gene3D G3DSA:3.40.190.10 92 175 3.3E-22 T 29-03-2018 A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 Gene3D G3DSA:3.20.20.150 1 279 1.0E-39 T 29-03-2018 A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 272 1.3E-55 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 SMART SM00518 2 275 3.8E-56 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 Pfam PF01261 Xylose isomerase-like TIM barrel 22 233 3.5E-24 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 SUPERFAMILY SSF51658 1 261 1.57E-59 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 171 178 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A616_RS12345 2a5b44178fa07052fcdd428c706aa367 280 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 209 225 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A616_RS29705 0ffa17dfa4ea5e9491631a85455ba12d 266 Pfam PF01061 ABC-2 type transporter 19 221 2.1E-15 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A616_RS27620 5ad0161e971d718de0dfbce60570245a 254 Pfam PF08241 Methyltransferase domain 56 142 9.3E-8 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS27620 5ad0161e971d718de0dfbce60570245a 254 Gene3D G3DSA:3.40.50.150 20 236 2.5E-14 T 29-03-2018 A616_RS27620 5ad0161e971d718de0dfbce60570245a 254 SUPERFAMILY SSF53335 37 190 1.53E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS12865 5346b99fc1de80daaf84c666239b925f 254 SUPERFAMILY SSF88713 3 251 2.52E-82 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS12865 5346b99fc1de80daaf84c666239b925f 254 Gene3D G3DSA:3.20.20.370 3 250 1.4E-87 T 29-03-2018 A616_RS12865 5346b99fc1de80daaf84c666239b925f 254 Pfam PF03746 LamB/YcsF family 5 239 1.5E-85 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 Gene3D G3DSA:3.40.50.300 160 449 1.5E-72 T 29-03-2018 A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 SUPERFAMILY SSF48024 3 112 1.02E-32 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 Gene3D G3DSA:1.10.860.10 3 144 1.8E-35 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 Pfam PF00772 DnaB-like helicase N terminal domain 7 105 1.0E-31 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 SUPERFAMILY SSF52540 177 428 6.4E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 Pfam PF03796 DnaB-like helicase C terminal domain 179 435 2.1E-114 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A616_RS06235 109451301913e4b8286cc6f30bcc8712 463 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 7 437 1.6E-167 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A616_RS32235 3fde334bbeb7e4ad75f6a50bfc189e4d 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 124 3.6E-30 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A616_RS32235 3fde334bbeb7e4ad75f6a50bfc189e4d 299 SUPERFAMILY SSF111331 3 299 1.16E-76 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A616_RS32235 3fde334bbeb7e4ad75f6a50bfc189e4d 299 SMART SM00046 1 125 3.0E-12 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 A616_RS32235 3fde334bbeb7e4ad75f6a50bfc189e4d 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 297 9.9E-53 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase A616_RS32235 3fde334bbeb7e4ad75f6a50bfc189e4d 299 Gene3D G3DSA:3.40.50.10330 1 130 2.3E-32 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A616_RS08765 d2f3694a3dc917459bdf4cb62b5a569a 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 300 2.7E-96 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS08765 d2f3694a3dc917459bdf4cb62b5a569a 310 SUPERFAMILY SSF53590 1 305 8.63E-99 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS08765 d2f3694a3dc917459bdf4cb62b5a569a 310 Gene3D G3DSA:3.90.245.10 1 308 2.3E-113 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 Gene3D G3DSA:3.20.20.70 1 324 1.1E-152 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 SUPERFAMILY SSF51569 4 323 4.4E-141 T 29-03-2018 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 SMART SM01004 3 322 5.2E-234 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PIRSF PIRSF001415 1 324 5.4E-152 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 6.0E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 6.0E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 6.0E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 6.0E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 6.0E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 6.0E-58 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS10350 7c94856119905efbe8a4c686cbc1b6d4 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 321 6.9E-149 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A616_RS21310 52eafd3ce0801c9a911df5071d6d4f84 323 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 315 1.8E-117 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS21310 52eafd3ce0801c9a911df5071d6d4f84 323 Pfam PF00953 Glycosyl transferase family 4 81 245 3.0E-38 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS21310 52eafd3ce0801c9a911df5071d6d4f84 323 ProSitePatterns PS01348 MraY family signature 2. 165 176 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS21310 52eafd3ce0801c9a911df5071d6d4f84 323 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 6 319 24.184 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS21310 52eafd3ce0801c9a911df5071d6d4f84 323 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 49 61 1.5E-4 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 70.542 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 Gene3D G3DSA:3.40.50.9100 1 146 1.4E-64 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 139 2.0E-39 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 SUPERFAMILY SSF52304 3 144 2.35E-61 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 Pfam PF01220 Dehydroquinase class II 4 139 6.1E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 1.0E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS12995 d7f854ad75ddb5b344c0d3c6d4150164 146 PIRSF PIRSF001399 1 146 6.7E-59 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 SUPERFAMILY SSF56235 1 226 6.69E-67 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 Pfam PF00733 Asparagine synthase 243 598 2.2E-83 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 Gene3D G3DSA:3.40.50.620 224 605 1.3E-58 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 SUPERFAMILY SSF52402 229 395 3.97E-64 T 29-03-2018 A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 SUPERFAMILY SSF52402 452 574 3.97E-64 T 29-03-2018 A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 532 1.8E-153 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 Gene3D G3DSA:3.60.20.10 1 223 1.1E-57 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.2E-48 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A616_RS22020 991768ce46dcd8e1087f051b1a122d65 605 PIRSF PIRSF001589 1 604 2.6E-140 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 SMART SM00244 34 195 3.0E-28 T 29-03-2018 IPR001107 Band 7 domain A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 SUPERFAMILY SSF117892 66 200 9.81E-16 T 29-03-2018 IPR001107 Band 7 domain A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 Pfam PF01145 SPFH domain / Band 7 family 38 226 4.9E-30 T 29-03-2018 IPR001107 Band 7 domain A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 119 137 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 213 229 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 142 158 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 96 115 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 78 94 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 165 184 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS08655 fea5e96b40aadaaea8214688a2e0a579 276 PRINTS PR00679 Prohibitin signature 190 213 1.5E-25 T 29-03-2018 IPR000163 Prohibitin GO:0016020 Reactome: R-HSA-8949664 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 SUPERFAMILY SSF81442 23 550 3.14E-105 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 228 282 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 Gene3D G3DSA:1.20.210.10 7 554 7.3E-84 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 226 247 2.6E-16 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 59 82 2.6E-16 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 428 449 2.6E-16 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 318 2.6E-16 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 128 140 2.6E-16 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02385 0a310e270c86f3434b9b5634ba5cf2db 557 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 24 475 2.1E-84 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS19840 09cadf1c2b3ee728ea1dcc5d8f3a93af 421 SUPERFAMILY SSF50156 179 271 1.45E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS19840 09cadf1c2b3ee728ea1dcc5d8f3a93af 421 Pfam PF13180 PDZ domain 211 272 1.0E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS19840 09cadf1c2b3ee728ea1dcc5d8f3a93af 421 SMART SM00228 190 263 6.6E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 A616_RS19840 09cadf1c2b3ee728ea1dcc5d8f3a93af 421 Pfam PF02163 Peptidase family M50 15 407 1.2E-74 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A616_RS19840 09cadf1c2b3ee728ea1dcc5d8f3a93af 421 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 12 420 5.4E-90 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A616_RS19840 09cadf1c2b3ee728ea1dcc5d8f3a93af 421 Gene3D G3DSA:2.30.42.10 199 276 5.7E-20 T 29-03-2018 A616_RS18115 c0be0f47891b44598424900c750818a0 295 Pfam PF01380 SIS domain 132 256 3.4E-14 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS18115 c0be0f47891b44598424900c750818a0 295 Gene3D G3DSA:3.40.50.10490 97 282 8.5E-21 T 29-03-2018 A616_RS18115 c0be0f47891b44598424900c750818a0 295 SUPERFAMILY SSF53697 100 277 1.84E-21 T 29-03-2018 A616_RS18115 c0be0f47891b44598424900c750818a0 295 Gene3D G3DSA:1.10.10.10 1 78 1.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18115 c0be0f47891b44598424900c750818a0 295 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 76 1.6E-12 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A616_RS18115 c0be0f47891b44598424900c750818a0 295 SUPERFAMILY SSF46689 6 75 3.05E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 SUPERFAMILY SSF100950 78 233 1.94E-26 T 29-03-2018 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 SMART SM01134 73 232 1.1E-46 T 29-03-2018 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.8E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.8E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 SUPERFAMILY SSF46785 4 63 1.93E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.1E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 Pfam PF00455 DeoR C terminal sensor domain 77 231 1.8E-41 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 Gene3D G3DSA:1.10.10.10 2 73 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 Gene3D G3DSA:3.40.50.1360 75 238 4.0E-32 T 29-03-2018 A616_RS20325 03e902ed26b0a23d7a2fee54511f1c5d 253 SMART SM00420 6 58 9.2E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS22805 06a081d047caf77d908786e7ea9bd95b 439 Pfam PF07690 Major Facilitator Superfamily 21 372 5.6E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS22805 06a081d047caf77d908786e7ea9bd95b 439 Gene3D G3DSA:1.20.1250.20 231 425 1.9E-13 T 29-03-2018 A616_RS22805 06a081d047caf77d908786e7ea9bd95b 439 Gene3D G3DSA:1.20.1250.20 11 216 6.4E-21 T 29-03-2018 A616_RS22805 06a081d047caf77d908786e7ea9bd95b 439 SUPERFAMILY SSF103473 16 419 4.71E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02060 b994b2c4d0bcaa2422ca11d6fa5920a4 127 SUPERFAMILY SSF142906 18 126 5.62E-15 T 29-03-2018 A616_RS02060 b994b2c4d0bcaa2422ca11d6fa5920a4 127 Gene3D G3DSA:3.30.1460.30 12 116 2.4E-6 T 29-03-2018 A616_RS02060 b994b2c4d0bcaa2422ca11d6fa5920a4 127 Pfam PF04237 YjbR 24 111 1.6E-11 T 29-03-2018 IPR007351 Uncharacterised protein YjbR A616_RS11640 fd19d2f6d3c422c2ae01ddf09c14af30 123 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 66 77 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A616_RS11640 fd19d2f6d3c422c2ae01ddf09c14af30 123 Gene3D G3DSA:1.10.3830.10 3 115 9.6E-42 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A616_RS11640 fd19d2f6d3c422c2ae01ddf09c14af30 123 Pfam PF01219 Prokaryotic diacylglycerol kinase 13 113 3.2E-36 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A616_RS05260 4039efd74de16556403044592673dd6e 418 PRINTS PR01035 Tetracycline resistance protein signature 76 100 1.8E-12 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05260 4039efd74de16556403044592673dd6e 418 PRINTS PR01035 Tetracycline resistance protein signature 344 367 1.8E-12 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05260 4039efd74de16556403044592673dd6e 418 PRINTS PR01035 Tetracycline resistance protein signature 309 329 1.8E-12 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05260 4039efd74de16556403044592673dd6e 418 PRINTS PR01035 Tetracycline resistance protein signature 133 155 1.8E-12 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05260 4039efd74de16556403044592673dd6e 418 Pfam PF07690 Major Facilitator Superfamily 11 360 3.1E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05260 4039efd74de16556403044592673dd6e 418 Gene3D G3DSA:1.20.1250.20 200 403 9.9E-18 T 29-03-2018 A616_RS05260 4039efd74de16556403044592673dd6e 418 Gene3D G3DSA:1.20.1250.20 1 196 2.3E-19 T 29-03-2018 A616_RS05260 4039efd74de16556403044592673dd6e 418 SUPERFAMILY SSF103473 5 401 4.45E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 145.277 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 Pfam PF08222 CodY helix-turn-helix domain 197 257 1.3E-36 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 SUPERFAMILY SSF46785 167 256 9.51E-42 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 PIRSF PIRSF011572 1 257 1.8E-120 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 Pfam PF06018 CodY GAF-like domain 3 178 6.2E-76 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 Gene3D G3DSA:1.10.10.10 160 259 6.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 3.5E-122 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 A616_RS20060 d73f0f1f336ff7fa99d3f63e59f782ea 259 Gene3D G3DSA:3.30.450.40 1 159 2.2E-29 T 29-03-2018 IPR029016 GAF domain-like A616_RS26875 d32cba12f4144b37b28109f59b836330 580 Pfam PF00005 ABC transporter 353 500 5.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS26875 d32cba12f4144b37b28109f59b836330 580 SUPERFAMILY SSF52540 330 573 2.0E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26875 d32cba12f4144b37b28109f59b836330 580 Gene3D G3DSA:3.40.50.300 324 578 1.9E-71 T 29-03-2018 A616_RS26875 d32cba12f4144b37b28109f59b836330 580 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS26875 d32cba12f4144b37b28109f59b836330 580 Pfam PF00664 ABC transporter transmembrane region 20 291 1.7E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS26875 d32cba12f4144b37b28109f59b836330 580 SMART SM00382 362 554 1.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS26875 d32cba12f4144b37b28109f59b836330 580 SUPERFAMILY SSF90123 6 320 4.71E-68 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS26875 d32cba12f4144b37b28109f59b836330 580 Gene3D G3DSA:1.20.1560.10 1 323 3.3E-57 T 29-03-2018 A616_RS06575 c40f062c7893e56f4f9b07fdb6cd89df 279 Gene3D G3DSA:1.25.40.70 55 176 0.13 T 29-03-2018 A616_RS06575 c40f062c7893e56f4f9b07fdb6cd89df 279 Pfam PF08713 DNA alkylation repair enzyme 155 246 1.7E-6 T 29-03-2018 IPR014825 DNA alkylation repair enzyme A616_RS06575 c40f062c7893e56f4f9b07fdb6cd89df 279 Gene3D G3DSA:1.25.40.290 177 276 2.9E-18 T 29-03-2018 A616_RS06575 c40f062c7893e56f4f9b07fdb6cd89df 279 SUPERFAMILY SSF48371 93 273 9.12E-34 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 SMART SM00345 7 66 2.7E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 SUPERFAMILY SSF46785 2 76 4.55E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 Gene3D G3DSA:3.90.1150.10 320 449 4.3E-10 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 Pfam PF00155 Aminotransferase class I and II 97 369 1.4E-25 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 Gene3D G3DSA:3.40.640.10 105 319 4.8E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 Gene3D G3DSA:1.10.10.10 1 74 2.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 SUPERFAMILY SSF53383 60 447 1.89E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS24375 48a9cb2f0a4bf3622b7ed93a80729526 449 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 9 168 40.256 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 138 144 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 SUPERFAMILY SSF53155 5 92 1.2E-17 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 89 167 2.8E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 Gene3D G3DSA:3.30.160.70 1 83 3.7E-19 T 29-03-2018 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 Gene3D G3DSA:1.10.10.10 84 169 2.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 88 167 2.1E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 SUPERFAMILY SSF46767 87 168 3.14E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS06120 5494ad2c251397a45c19134ac5b856e4 178 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 79 2.0E-12 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS02665 52a90d8229938df6107b197aad0d15ab 410 SUPERFAMILY SSF103473 12 402 2.35E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02665 52a90d8229938df6107b197aad0d15ab 410 Gene3D G3DSA:1.20.1250.20 7 205 7.6E-27 T 29-03-2018 A616_RS02665 52a90d8229938df6107b197aad0d15ab 410 Gene3D G3DSA:1.20.1250.20 206 409 5.9E-22 T 29-03-2018 A616_RS02665 52a90d8229938df6107b197aad0d15ab 410 Pfam PF07690 Major Facilitator Superfamily 19 277 7.2E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS11075 4b331a94cc1dfca812aa73bb533f88a1 257 Pfam PF13115 YtkA-like 37 112 2.2E-16 T 29-03-2018 IPR032693 YtkA-like domain A616_RS11075 4b331a94cc1dfca812aa73bb533f88a1 257 Pfam PF13115 YtkA-like 158 240 4.0E-12 T 29-03-2018 IPR032693 YtkA-like domain A616_RS11075 4b331a94cc1dfca812aa73bb533f88a1 257 Gene3D G3DSA:2.60.40.10 30 132 6.1E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS11075 4b331a94cc1dfca812aa73bb533f88a1 257 Gene3D G3DSA:2.60.40.10 155 257 2.8E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 6.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 6.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 6.4E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 Gene3D G3DSA:1.10.10.10 1 51 4.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 Pfam PF01037 Lrp/AsnC ligand binding domain 78 139 4.4E-8 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 Gene3D G3DSA:3.30.70.920 57 148 8.3E-17 T 29-03-2018 A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 1.7E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 SUPERFAMILY SSF46785 3 62 2.32E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 SUPERFAMILY SSF54909 63 142 6.57E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS13360 c3a2a2129f97577eb2f3bea9717c5470 156 SMART SM00344 4 109 7.8E-32 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS25130 8df110247ed6d82a9044df8c5cfd309e 334 Pfam PF05544 Proline racemase 10 331 9.2E-118 T 29-03-2018 IPR008794 Proline racemase family A616_RS25130 8df110247ed6d82a9044df8c5cfd309e 334 Gene3D G3DSA:3.10.310.10 154 309 4.1E-61 T 29-03-2018 A616_RS25130 8df110247ed6d82a9044df8c5cfd309e 334 Gene3D G3DSA:3.10.310.10 1 153 5.7E-36 T 29-03-2018 A616_RS25130 8df110247ed6d82a9044df8c5cfd309e 334 SUPERFAMILY SSF54506 1 331 8.08E-113 T 29-03-2018 A616_RS25130 8df110247ed6d82a9044df8c5cfd309e 334 PIRSF PIRSF029792 1 334 4.0E-135 T 29-03-2018 IPR008794 Proline racemase family A616_RS22490 6e981e4ab6279905bbb184a0098a3ef6 250 TIGRFAM TIGR00552 nadE: NAD+ synthetase 16 248 2.0E-66 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A616_RS22490 6e981e4ab6279905bbb184a0098a3ef6 250 Gene3D G3DSA:3.40.50.620 3 250 1.7E-64 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS22490 6e981e4ab6279905bbb184a0098a3ef6 250 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 13 250 31.186 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A616_RS22490 6e981e4ab6279905bbb184a0098a3ef6 250 SUPERFAMILY SSF52402 10 248 2.87E-71 T 29-03-2018 A616_RS22490 6e981e4ab6279905bbb184a0098a3ef6 250 Pfam PF02540 NAD synthase 19 244 5.4E-65 T 29-03-2018 IPR022310 NAD/GMP synthase A616_RS22075 b129f766a20199613071f5a46be9e71e 177 SMART SM00738 2 111 7.1E-8 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 SUPERFAMILY SSF50104 125 173 5.01E-7 T 29-03-2018 IPR008991 Translation protein SH3-like domain A616_RS22075 b129f766a20199613071f5a46be9e71e 177 Pfam PF00467 KOW motif 128 155 5.1E-5 T 29-03-2018 IPR005824 KOW A616_RS22075 b129f766a20199613071f5a46be9e71e 177 Gene3D G3DSA:2.30.30.30 121 175 3.9E-7 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 Gene3D G3DSA:3.30.70.940 1 112 2.5E-23 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 SUPERFAMILY SSF82679 2 114 4.45E-20 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 Pfam PF02357 Transcription termination factor nusG 2 104 1.6E-16 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 PRINTS PR00338 Transcription termination factor NUSG signature 50 62 6.7E-6 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 PRINTS PR00338 Transcription termination factor NUSG signature 152 168 6.7E-6 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS22075 b129f766a20199613071f5a46be9e71e 177 PRINTS PR00338 Transcription termination factor NUSG signature 134 149 6.7E-6 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 Pfam PF04055 Radical SAM superfamily 70 225 5.9E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 TIGRFAM TIGR00433 bioB: biotin synthase 32 325 1.6E-121 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 325 1.4E-15 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 SMART SM00729 60 268 5.1E-34 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 SUPERFAMILY SSF102114 20 326 1.7E-72 T 29-03-2018 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 PIRSF PIRSF001619 3 331 5.6E-124 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 Gene3D G3DSA:3.20.20.70 19 329 1.1E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 Hamap MF_01694 Biotin synthase [bioB]. 20 327 41.1 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A616_RS29970 8dae9d9a8c4ed9431a044459844d9fe3 331 SMART SM00876 236 326 3.7E-32 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A616_RS04160 43bd26e409f0e47e5504d7d6c77a3690 351 Gene3D G3DSA:3.40.50.1010 1 199 4.1E-12 T 29-03-2018 IPR029060 PIN domain-like A616_RS04160 43bd26e409f0e47e5504d7d6c77a3690 351 Pfam PF16289 Domain of unknown function (DUF4935) 4 227 1.6E-26 T 29-03-2018 IPR032557 Protein of unknown function DUF4935 A616_RS31915 d9cc5201e0268ad86f9995abc4a67fd2 212 Pfam PF00583 Acetyltransferase (GNAT) family 63 190 4.6E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS31915 d9cc5201e0268ad86f9995abc4a67fd2 212 SUPERFAMILY SSF55729 5 95 1.86E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS31915 d9cc5201e0268ad86f9995abc4a67fd2 212 SUPERFAMILY SSF55729 126 200 1.86E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS31915 d9cc5201e0268ad86f9995abc4a67fd2 212 Gene3D G3DSA:3.40.630.30 1 203 9.8E-21 T 29-03-2018 A616_RS30530 3b0697ada733af2fd1f6dd7016a9cc94 304 Gene3D G3DSA:1.10.3470.10 3 297 1.2E-38 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS30530 3b0697ada733af2fd1f6dd7016a9cc94 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 286 9.1E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS14235 26481121f30c1f04486db9e9b5b14f44 543 Gene3D G3DSA:1.10.10.60 463 514 5.7E-7 T 29-03-2018 A616_RS14235 26481121f30c1f04486db9e9b5b14f44 543 Pfam PF13556 PucR C-terminal helix-turn-helix domain 478 535 2.1E-18 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS14235 26481121f30c1f04486db9e9b5b14f44 543 Pfam PF07905 Purine catabolism regulatory protein-like family 15 129 4.6E-20 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain A616_RS18155 d1a862f562324f0756df3bc4d0b7e87d 536 SMART SM00382 269 405 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS18155 d1a862f562324f0756df3bc4d0b7e87d 536 Gene3D G3DSA:1.10.8.60 411 513 5.4E-6 T 29-03-2018 A616_RS18155 d1a862f562324f0756df3bc4d0b7e87d 536 Gene3D G3DSA:3.40.50.300 227 410 1.4E-31 T 29-03-2018 A616_RS18155 d1a862f562324f0756df3bc4d0b7e87d 536 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 273 402 1.7E-26 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS18155 d1a862f562324f0756df3bc4d0b7e87d 536 SUPERFAMILY SSF52540 235 490 5.49E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09240 7721c51e579d5742d1b1cfe7520ac347 406 Pfam PF07690 Major Facilitator Superfamily 17 323 3.4E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS09240 7721c51e579d5742d1b1cfe7520ac347 406 Gene3D G3DSA:1.20.1250.20 2 196 1.9E-33 T 29-03-2018 A616_RS09240 7721c51e579d5742d1b1cfe7520ac347 406 SUPERFAMILY SSF103473 6 388 1.44E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09240 7721c51e579d5742d1b1cfe7520ac347 406 Gene3D G3DSA:1.20.1250.20 207 401 4.2E-18 T 29-03-2018 A616_RS18715 17ca23305d9f7f0d4c35a0311f1b3d35 296 SUPERFAMILY SSF56317 4 292 7.59E-78 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS18715 17ca23305d9f7f0d4c35a0311f1b3d35 296 Pfam PF00795 Carbon-nitrogen hydrolase 9 274 1.2E-58 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS18715 17ca23305d9f7f0d4c35a0311f1b3d35 296 Gene3D G3DSA:3.60.110.10 1 295 2.8E-72 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.5E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.5E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 Pfam PF00455 DeoR C terminal sensor domain 75 232 8.0E-56 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 3.5E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 Gene3D G3DSA:1.10.10.10 1 58 1.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 SMART SM01134 73 234 1.1E-75 T 29-03-2018 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 SMART SM00420 6 58 4.9E-20 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 SUPERFAMILY SSF100950 76 234 1.84E-36 T 29-03-2018 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 Gene3D G3DSA:3.40.50.1360 73 240 6.6E-47 T 29-03-2018 A616_RS31820 a07c47e0bacda6b9e24274e472d20330 259 SUPERFAMILY SSF46785 5 78 6.84E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09740 b106b7b2912b2f8a67c8ffe5439a5ca6 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 276 1.2E-43 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS09740 b106b7b2912b2f8a67c8ffe5439a5ca6 288 Gene3D G3DSA:1.10.3470.10 1 281 7.6E-51 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS27815 a399cd646dcedbb58ed78f35c976d632 295 Gene3D G3DSA:1.10.3720.10 64 291 5.6E-35 T 29-03-2018 A616_RS27815 a399cd646dcedbb58ed78f35c976d632 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 290 2.3E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS27815 a399cd646dcedbb58ed78f35c976d632 295 SUPERFAMILY SSF161098 57 283 2.35E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS27815 a399cd646dcedbb58ed78f35c976d632 295 Gene3D G3DSA:1.20.58.370 5 46 3.0E-6 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS27815 a399cd646dcedbb58ed78f35c976d632 295 SUPERFAMILY SSF160964 18 46 5.49E-5 T 29-03-2018 A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 Gene3D G3DSA:3.40.190.10 286 359 8.2E-5 T 29-03-2018 A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 177 492 4.9E-40 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 Gene3D G3DSA:3.10.105.10 373 581 9.3E-13 T 29-03-2018 A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 Pfam PF12793 Sugar transport-related sRNA regulator N-term 14 111 9.9E-18 T 29-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 PIRSF PIRSF002741 121 612 3.5E-49 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 SUPERFAMILY SSF53850 131 608 7.24E-76 T 29-03-2018 A616_RS24625 bc17fc7481e676265f0cc292a74c32fc 617 Gene3D G3DSA:3.90.76.10 140 285 7.2E-34 T 29-03-2018 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 38.95 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 SUPERFAMILY SSF47648 5 68 1.7E-17 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 65 3.4E-19 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 Pfam PF00591 Glycosyl transferase family, a/b domain 73 321 9.8E-101 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 Gene3D G3DSA:1.20.970.10 3 66 1.7E-19 T 29-03-2018 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 Gene3D G3DSA:3.40.1030.10 70 340 2.5E-106 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 SUPERFAMILY SSF52418 73 337 1.31E-96 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS13810 8dee17382d7e010efa74fd9bb9483e2d 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 330 1.1E-128 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A616_RS31410 d2b1ed6c3fda0636521e81d55b1b79aa 146 Gene3D G3DSA:1.20.144.10 1 143 6.4E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS31410 d2b1ed6c3fda0636521e81d55b1b79aa 146 Pfam PF02681 Divergent PAP2 family 5 129 7.0E-31 T 29-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related A616_RS23845 ee100a895f8c4e44b6664a787d56c131 180 PIRSF PIRSF000232 1 179 2.1E-37 T 29-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like A616_RS23845 ee100a895f8c4e44b6664a787d56c131 180 Pfam PF00881 Nitroreductase family 7 156 1.3E-22 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS23845 ee100a895f8c4e44b6664a787d56c131 180 SUPERFAMILY SSF55469 4 177 4.45E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS23845 ee100a895f8c4e44b6664a787d56c131 180 Gene3D G3DSA:3.40.109.10 1 180 5.8E-28 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS19110 52fb57a99137163d4564b30d6f26a602 87 Gene3D G3DSA:1.10.10.60 44 87 1.5E-11 T 29-03-2018 A616_RS19110 52fb57a99137163d4564b30d6f26a602 87 SUPERFAMILY SSF46689 8 85 1.25E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 SMART SM00382 52 249 1.7E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 Gene3D G3DSA:3.10.580.10 280 408 3.5E-18 T 29-03-2018 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 35 388 2.9E-144 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 Pfam PF00571 CBS domain 279 325 1.5E-5 T 29-03-2018 IPR000644 CBS domain A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 Pfam PF00571 CBS domain 336 381 0.0057 T 29-03-2018 IPR000644 CBS domain A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 Pfam PF00005 ABC transporter 44 191 5.9E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 SUPERFAMILY SSF54631 276 389 1.52E-19 T 29-03-2018 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 Gene3D G3DSA:3.40.50.300 1 279 5.9E-73 T 29-03-2018 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 SMART SM00116 281 329 3.6E-5 T 29-03-2018 IPR000644 CBS domain A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 SMART SM00116 341 388 5.4 T 29-03-2018 IPR000644 CBS domain A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02230 737470f9d67a1ec0ec79b8a9f7b26820 408 SUPERFAMILY SSF52540 32 270 8.07E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21650 256478c2dd976f33d11614b3576bacae 146 Pfam PF00258 Flavodoxin 6 134 3.2E-26 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A616_RS21650 256478c2dd976f33d11614b3576bacae 146 Gene3D G3DSA:3.40.50.360 1 145 6.4E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS21650 256478c2dd976f33d11614b3576bacae 146 TIGRFAM TIGR01753 flav_short: flavodoxin 3 141 6.1E-44 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 A616_RS21650 256478c2dd976f33d11614b3576bacae 146 SUPERFAMILY SSF52218 1 145 5.55E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 Gene3D G3DSA:1.25.40.20 155 235 3.7E-14 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 Pfam PF12796 Ankyrin repeats (3 copies) 148 223 3.0E-6 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 Gene3D G3DSA:1.25.40.20 11 154 2.0E-15 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 Pfam PF13637 Ankyrin repeats (many copies) 51 97 2.5E-5 T 29-03-2018 A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 SMART SM00248 140 169 230.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 SMART SM00248 178 207 0.0028 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 SMART SM00248 48 77 0.13 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 SMART SM00248 78 107 13.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 A616_RS31960 90c025dcc7eb76f85176fabb26f80f6f 359 SUPERFAMILY SSF48403 19 234 4.54E-27 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain A616_RS16740 e24f13a7950ab51eee2ad47d69d8f3ae 488 SUPERFAMILY SSF52540 196 261 2.55E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16740 e24f13a7950ab51eee2ad47d69d8f3ae 488 SUPERFAMILY SSF52540 292 379 2.55E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16740 e24f13a7950ab51eee2ad47d69d8f3ae 488 Pfam PF03796 DnaB-like helicase C terminal domain 198 380 5.8E-11 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A616_RS16740 e24f13a7950ab51eee2ad47d69d8f3ae 488 Gene3D G3DSA:3.40.50.300 177 488 8.6E-14 T 29-03-2018 A616_RS30870 0a1941bd0493bcdf8922664845013e65 179 Gene3D G3DSA:3.90.70.10 34 171 2.5E-10 T 29-03-2018 A616_RS30870 0a1941bd0493bcdf8922664845013e65 179 Pfam PF13529 Peptidase_C39 like family 13 127 4.1E-6 T 29-03-2018 A616_RS15735 eb7a6da44605fad28914c05607edb570 263 SUPERFAMILY SSF48256 4 235 3.66E-44 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS15735 eb7a6da44605fad28914c05607edb570 263 Pfam PF00285 Citrate synthase, C-terminal domain 37 235 3.9E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 A616_RS15735 eb7a6da44605fad28914c05607edb570 263 Gene3D G3DSA:1.10.230.10 101 211 2.5E-18 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain A616_RS15735 eb7a6da44605fad28914c05607edb570 263 ProSitePatterns PS00480 Citrate synthase signature. 142 154 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A616_RS10850 211a79cae021b602150cf7b378179633 96 Pfam PF06949 Protein of unknown function (DUF1292) 19 88 5.3E-15 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 A616_RS00670 e870df61b3efe4a56484bcc4dacdf9e3 95 Gene3D G3DSA:3.30.1120.40 1 83 2.8E-36 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A616_RS00670 e870df61b3efe4a56484bcc4dacdf9e3 95 Pfam PF04026 SpoVG 1 81 1.0E-35 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A616_RS00670 e870df61b3efe4a56484bcc4dacdf9e3 95 SUPERFAMILY SSF160537 1 85 6.93E-33 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A616_RS00670 e870df61b3efe4a56484bcc4dacdf9e3 95 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 93 27.933 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 A616_RS13470 4fe5b617d2d8f67aa526f25f2cc806b5 254 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 245 25.225 T 29-03-2018 IPR003768 Segregation and condensation protein A A616_RS13470 4fe5b617d2d8f67aa526f25f2cc806b5 254 Gene3D G3DSA:1.10.10.580 177 242 1.0E-13 T 29-03-2018 A616_RS13470 4fe5b617d2d8f67aa526f25f2cc806b5 254 Pfam PF02616 Segregation and condensation protein ScpA 20 242 1.5E-44 T 29-03-2018 IPR003768 Segregation and condensation protein A A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 337 8.7E-138 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 SUPERFAMILY SSF100950 7 341 4.88E-126 T 29-03-2018 A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 Gene3D G3DSA:1.20.120.420 7 147 6.7E-52 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 6 345 39.713 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 338 3.0E-118 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 Pfam PF01008 Initiation factor 2 subunit family 48 338 4.5E-88 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A616_RS26885 911f118dbb78b1a6c4039584fdf6edea 346 Gene3D G3DSA:3.40.50.10470 148 344 2.0E-69 T 29-03-2018 A616_RS24645 31c5249098c2ebaff4b89d28aee478c4 343 SUPERFAMILY SSF81345 8 340 2.09E-85 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS24645 31c5249098c2ebaff4b89d28aee478c4 343 Gene3D G3DSA:1.10.3470.10 11 343 6.6E-69 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS24645 31c5249098c2ebaff4b89d28aee478c4 343 Pfam PF01032 FecCD transport family 26 340 3.6E-94 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS06000 ac5a94ececb9feb67c2d1e730fb66235 144 Gene3D G3DSA:1.10.10.10 1 87 9.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06000 ac5a94ececb9feb67c2d1e730fb66235 144 Pfam PF01475 Ferric uptake regulator family 15 133 7.7E-38 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A616_RS06000 ac5a94ececb9feb67c2d1e730fb66235 144 SUPERFAMILY SSF46785 6 137 1.62E-40 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04730 e048b33557a04eb1f0b06df8a736e628 543 SUPERFAMILY SSF53850 46 538 3.86E-135 T 29-03-2018 A616_RS04730 e048b33557a04eb1f0b06df8a736e628 543 PIRSF PIRSF002741 1 542 1.6E-117 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS04730 e048b33557a04eb1f0b06df8a736e628 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 464 2.4E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS04730 e048b33557a04eb1f0b06df8a736e628 543 Gene3D G3DSA:3.90.76.10 60 179 7.0E-34 T 29-03-2018 A616_RS04730 e048b33557a04eb1f0b06df8a736e628 543 Gene3D G3DSA:3.10.105.10 318 513 6.2E-51 T 29-03-2018 A616_RS04730 e048b33557a04eb1f0b06df8a736e628 543 Gene3D G3DSA:3.40.190.10 180 317 1.0E-45 T 29-03-2018 A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 SMART SM00344 1 111 6.1E-28 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 7.6E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 7.6E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 7.6E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 7.3E-16 T 29-03-2018 A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 Pfam PF01037 Lrp/AsnC ligand binding domain 92 141 2.5E-7 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 Gene3D G3DSA:1.10.10.10 1 52 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 SUPERFAMILY SSF54909 64 146 1.03E-9 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 SUPERFAMILY SSF46785 1 59 5.26E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS07035 136f7b157be7e81055966ec417b2e7c1 150 Gene3D G3DSA:3.30.70.920 53 150 4.7E-16 T 29-03-2018 A616_RS30635 46a850b330753cc25f290fc306addd08 326 Gene3D G3DSA:3.90.380.10 114 323 5.1E-27 T 29-03-2018 A616_RS30635 46a850b330753cc25f290fc306addd08 326 Gene3D G3DSA:2.102.10.10 9 113 9.4E-27 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS30635 46a850b330753cc25f290fc306addd08 326 SUPERFAMILY SSF55961 119 321 1.59E-17 T 29-03-2018 A616_RS30635 46a850b330753cc25f290fc306addd08 326 SUPERFAMILY SSF50022 5 119 2.62E-34 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS30635 46a850b330753cc25f290fc306addd08 326 Pfam PF00355 Rieske [2Fe-2S] domain 11 89 6.1E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS30635 46a850b330753cc25f290fc306addd08 326 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 51 73 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 A616_RS06015 8f369353be6b0fad1ce8de3b7f297b2e 286 Gene3D G3DSA:1.20.120.330 115 228 1.3E-36 T 29-03-2018 A616_RS06015 8f369353be6b0fad1ce8de3b7f297b2e 286 Gene3D G3DSA:1.10.10.10 230 279 1.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06015 8f369353be6b0fad1ce8de3b7f297b2e 286 ProDom PD128250 YGXA BH0953 16 265 1.0E-30 T 29-03-2018 A616_RS06015 8f369353be6b0fad1ce8de3b7f297b2e 286 Gene3D G3DSA:3.30.460.10 2 110 3.8E-16 T 29-03-2018 A616_RS17525 46f61866bd8da77341953151d8436ae8 252 SMART SM00644 12 157 3.1E-13 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS17525 46f61866bd8da77341953151d8436ae8 252 Gene3D G3DSA:3.40.80.10 2 192 8.8E-35 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS17525 46f61866bd8da77341953151d8436ae8 252 SUPERFAMILY SSF55846 2 174 5.63E-34 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS17525 46f61866bd8da77341953151d8436ae8 252 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 20 156 1.4E-20 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A616_RS20770 d732afc38e5285d046f52492e2177b11 356 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 10 352 72.536 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS20770 d732afc38e5285d046f52492e2177b11 356 SUPERFAMILY SSF102114 98 324 1.44E-13 T 29-03-2018 A616_RS20770 d732afc38e5285d046f52492e2177b11 356 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 9 354 9.1E-147 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS20770 d732afc38e5285d046f52492e2177b11 356 Pfam PF04055 Radical SAM superfamily 113 287 1.9E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS20770 d732afc38e5285d046f52492e2177b11 356 PIRSF PIRSF006004 6 355 4.7E-136 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS20770 d732afc38e5285d046f52492e2177b11 356 Gene3D G3DSA:3.20.20.70 19 356 2.8E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 PIRSF PIRSF000105 1 283 1.5E-97 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 Gene3D G3DSA:3.40.50.720 1 185 4.8E-62 T 29-03-2018 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 9.5E-70 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 Gene3D G3DSA:1.10.1040.10 186 283 1.8E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 1.5E-37 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 SUPERFAMILY SSF51735 1 185 1.32E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30165 a7da482933b06ebc6dd76b83f9c6f1e8 283 SUPERFAMILY SSF48179 185 283 2.81E-35 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS18415 e2235d51919848341e6c72dec126e195 458 Gene3D G3DSA:1.10.10.60 386 424 9.9E-8 T 29-03-2018 A616_RS18415 e2235d51919848341e6c72dec126e195 458 Pfam PF13556 PucR C-terminal helix-turn-helix domain 388 446 2.3E-22 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS28355 dd8f0c60f25d3493e64ec77375285621 437 Gene3D G3DSA:1.10.10.60 305 376 0.0021 T 29-03-2018 A616_RS28355 dd8f0c60f25d3493e64ec77375285621 437 Gene3D G3DSA:1.10.10.10 377 436 1.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28355 dd8f0c60f25d3493e64ec77375285621 437 SUPERFAMILY SSF46785 378 435 2.07E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31875 e6c800b0dc18b036f89fa850b91e21b7 313 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 126 1.1E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS31875 e6c800b0dc18b036f89fa850b91e21b7 313 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 272 2.8E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS31875 e6c800b0dc18b036f89fa850b91e21b7 313 Gene3D G3DSA:3.10.180.10 148 313 2.5E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS31875 e6c800b0dc18b036f89fa850b91e21b7 313 SUPERFAMILY SSF54593 3 284 3.45E-42 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS31875 e6c800b0dc18b036f89fa850b91e21b7 313 Gene3D G3DSA:3.10.180.10 2 145 8.6E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS06750 10e36f02f5ab808c04922103ba336f8d 148 SMART SM00530 5 60 1.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS06750 10e36f02f5ab808c04922103ba336f8d 148 Pfam PF01381 Helix-turn-helix 6 60 5.6E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS06750 10e36f02f5ab808c04922103ba336f8d 148 SUPERFAMILY SSF47413 2 66 2.36E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS06750 10e36f02f5ab808c04922103ba336f8d 148 Gene3D G3DSA:1.10.3100.10 1 147 4.4E-26 T 29-03-2018 IPR027910 YdiL-like domain A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 Pfam PF00698 Acyl transferase domain 7 285 2.2E-40 T 29-03-2018 IPR014043 Acyl transferase A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 SUPERFAMILY SSF52151 199 288 2.3E-73 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 SUPERFAMILY SSF52151 3 128 2.3E-73 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 Gene3D G3DSA:3.40.366.10 1 137 1.9E-45 T 29-03-2018 A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 Gene3D G3DSA:3.30.70.250 138 188 5.6E-18 T 29-03-2018 A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 301 1.1E-47 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 287 4.5E-100 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 SUPERFAMILY SSF55048 130 198 2.09E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A616_RS18505 24e69f7af5e3e110a0bd786ccf1f16a1 422 Gene3D G3DSA:3.40.366.10 189 289 1.2E-25 T 29-03-2018 A616_RS12560 439a5ef12cd1c6f591de32328d5ae98b 268 SUPERFAMILY SSF161098 69 251 1.44E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12560 439a5ef12cd1c6f591de32328d5ae98b 268 Gene3D G3DSA:1.10.3720.10 19 268 2.5E-26 T 29-03-2018 A616_RS12560 439a5ef12cd1c6f591de32328d5ae98b 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 263 2.8E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.6E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 Gene3D G3DSA:1.10.10.60 2 56 2.3E-14 T 29-03-2018 A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 Gene3D G3DSA:1.10.357.10 57 190 5.4E-18 T 29-03-2018 A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 Pfam PF08359 YsiA-like protein, C-terminal region 59 189 1.8E-48 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 SUPERFAMILY SSF48498 80 192 5.26E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 SUPERFAMILY SSF46689 3 83 6.8E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS09705 090f71c905013dbacd1647624ce7fc44 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.1E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS05975 2bdefca8697b0d72f921fbefecfd7dce 350 PIRSF PIRSF001123 5 350 1.3E-39 T 29-03-2018 IPR008007 Peptidase M42 A616_RS05975 2bdefca8697b0d72f921fbefecfd7dce 350 SUPERFAMILY SSF53187 6 86 3.26E-56 T 29-03-2018 A616_RS05975 2bdefca8697b0d72f921fbefecfd7dce 350 SUPERFAMILY SSF53187 182 345 3.26E-56 T 29-03-2018 A616_RS05975 2bdefca8697b0d72f921fbefecfd7dce 350 Gene3D G3DSA:3.40.630.10 1 348 3.4E-50 T 29-03-2018 A616_RS05975 2bdefca8697b0d72f921fbefecfd7dce 350 Pfam PF05343 M42 glutamyl aminopeptidase 49 338 2.3E-84 T 29-03-2018 IPR008007 Peptidase M42 A616_RS05975 2bdefca8697b0d72f921fbefecfd7dce 350 SUPERFAMILY SSF101821 74 187 1.01E-29 T 29-03-2018 A616_RS05830 bca19b3948c2ac545a33b2838a67a5dc 178 Gene3D G3DSA:2.40.380.10 15 169 1.1E-30 T 29-03-2018 IPR007295 Domain of unknown function DUF402 A616_RS05830 bca19b3948c2ac545a33b2838a67a5dc 178 PIRSF PIRSF028345 1 178 9.7E-63 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 A616_RS05830 bca19b3948c2ac545a33b2838a67a5dc 178 Pfam PF04167 Protein of unknown function (DUF402) 59 123 1.3E-15 T 29-03-2018 IPR007295 Domain of unknown function DUF402 A616_RS05830 bca19b3948c2ac545a33b2838a67a5dc 178 SUPERFAMILY SSF159234 8 170 2.48E-27 T 29-03-2018 IPR007295 Domain of unknown function DUF402 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 Pfam PF00501 AMP-binding enzyme 12 413 3.5E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 Gene3D G3DSA:2.30.38.10 324 406 2.2E-24 T 29-03-2018 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 Gene3D G3DSA:3.30.300.30 408 514 7.0E-22 T 29-03-2018 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 496 4.6E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 Gene3D G3DSA:3.40.50.980 173 323 4.8E-36 T 29-03-2018 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 SUPERFAMILY SSF56801 8 509 1.31E-142 T 29-03-2018 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 Gene3D G3DSA:3.40.50.980 3 172 8.5E-40 T 29-03-2018 A616_RS16005 0324bf5e8ed3f9bb5851edd6ef1211ae 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 ProSitePatterns PS00519 AsnC-type HTH domain signature. 41 67 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 SUPERFAMILY SSF54909 87 156 4.83E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 Pfam PF13404 AsnC-type helix-turn-helix domain 24 64 8.4E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 Gene3D G3DSA:3.30.70.920 74 161 6.3E-15 T 29-03-2018 A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 Pfam PF01037 Lrp/AsnC ligand binding domain 94 152 1.1E-10 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 Gene3D G3DSA:1.10.10.10 24 73 4.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 50 69 7.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 39 7.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 50 7.7E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 SMART SM00344 23 127 7.3E-37 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS02160 bf8bf7e92bbfb2934a4c3bc00d066b66 168 SUPERFAMILY SSF46785 23 82 2.28E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 435 9.3E-70 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 Gene3D G3DSA:1.20.1250.20 1 197 8.9E-37 T 29-03-2018 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 Gene3D G3DSA:1.20.1250.20 253 530 2.2E-37 T 29-03-2018 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 2.3E-6 T 29-03-2018 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 2.3E-6 T 29-03-2018 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.3E-6 T 29-03-2018 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 402 421 2.3E-6 T 29-03-2018 A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 SUPERFAMILY SSF103473 6 197 5.62E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 SUPERFAMILY SSF103473 249 421 5.62E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 SUPERFAMILY SSF103473 494 518 5.62E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS04465 d1e60d00b24a7943deda3f0f47cedf0d 538 Pfam PF07690 Major Facilitator Superfamily 17 411 2.6E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS14510 52e437296f283a924c2a1a1831668938 355 Gene3D G3DSA:3.90.1240.10 119 175 1.3E-7 T 29-03-2018 A616_RS14510 52e437296f283a924c2a1a1831668938 355 SUPERFAMILY SSF57884 8 86 9.42E-31 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A616_RS14510 52e437296f283a924c2a1a1831668938 355 PIRSF PIRSF000409 1 352 3.4E-148 T 29-03-2018 IPR016221 Bifunctional regulatory protein Ada A616_RS14510 52e437296f283a924c2a1a1831668938 355 Gene3D G3DSA:3.30.160.70 176 260 2.5E-12 T 29-03-2018 A616_RS14510 52e437296f283a924c2a1a1831668938 355 SUPERFAMILY SSF46767 264 345 2.62E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS14510 52e437296f283a924c2a1a1831668938 355 Gene3D G3DSA:1.10.10.10 261 346 4.2E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14510 52e437296f283a924c2a1a1831668938 355 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 315 321 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS14510 52e437296f283a924c2a1a1831668938 355 SUPERFAMILY SSF53155 185 269 1.06E-11 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS14510 52e437296f283a924c2a1a1831668938 355 SMART SM00342 97 178 6.4E-7 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS14510 52e437296f283a924c2a1a1831668938 355 Gene3D G3DSA:1.10.10.60 75 118 6.9E-4 T 29-03-2018 A616_RS14510 52e437296f283a924c2a1a1831668938 355 Pfam PF02805 Metal binding domain of Ada 10 72 5.9E-28 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A616_RS14510 52e437296f283a924c2a1a1831668938 355 Gene3D G3DSA:3.40.10.10 2 74 1.1E-21 T 29-03-2018 IPR035451 Ada-like domain A616_RS14510 52e437296f283a924c2a1a1831668938 355 Pfam PF12833 Helix-turn-helix domain 105 175 3.7E-12 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS14510 52e437296f283a924c2a1a1831668938 355 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 266 344 6.9E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS14510 52e437296f283a924c2a1a1831668938 355 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 266 345 1.1E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS27425 538c01b41c6e711e6b382d1ad2402130 167 Gene3D G3DSA:3.30.300.130 9 108 7.9E-23 T 29-03-2018 IPR034904 Fe-S cluster assembly domain A616_RS27425 538c01b41c6e711e6b382d1ad2402130 167 SUPERFAMILY SSF117916 12 106 2.18E-23 T 29-03-2018 IPR034904 Fe-S cluster assembly domain A616_RS27425 538c01b41c6e711e6b382d1ad2402130 167 Pfam PF01883 Iron-sulfur cluster assembly protein 17 85 3.1E-15 T 29-03-2018 IPR002744 MIP18 family-like A616_RS27425 538c01b41c6e711e6b382d1ad2402130 167 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 23 166 2.0E-53 T 29-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 SUPERFAMILY SSF52540 4 243 3.41E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 Gene3D G3DSA:3.40.50.300 1 245 1.9E-70 T 29-03-2018 A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 Pfam PF00005 ABC transporter 21 162 2.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 SUPERFAMILY SSF50331 237 369 2.67E-25 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 SMART SM00382 29 212 2.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 Gene3D G3DSA:2.40.50.100 246 297 3.3E-13 T 29-03-2018 A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 Pfam PF08402 TOBE domain 286 362 3.2E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS11940 d44a083b3e4b9092d4d0ad90630e3529 371 Gene3D G3DSA:2.40.50.140 298 355 2.4E-15 T 29-03-2018 A616_RS27800 8d72889136a4ef1845fd4c2e83478cd6 244 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 206 6.7E-18 T 29-03-2018 IPR023214 HAD-like domain A616_RS27800 8d72889136a4ef1845fd4c2e83478cd6 244 SUPERFAMILY SSF56784 5 238 9.27E-37 T 29-03-2018 IPR023214 HAD-like domain A616_RS27800 8d72889136a4ef1845fd4c2e83478cd6 244 Gene3D G3DSA:3.40.50.1000 1 239 1.1E-21 T 29-03-2018 IPR023214 HAD-like domain A616_RS28240 dcf977c5f537a62507c2610cffa27631 291 Gene3D G3DSA:3.75.10.10 4 291 1.2E-45 T 29-03-2018 A616_RS28240 dcf977c5f537a62507c2610cffa27631 291 Pfam PF02274 Amidinotransferase 78 290 3.1E-34 T 29-03-2018 A616_RS28240 dcf977c5f537a62507c2610cffa27631 291 SUPERFAMILY SSF55909 5 290 1.39E-48 T 29-03-2018 A616_RS04415 65125b234bfc87ff6f40cbfac81f587b 205 SUPERFAMILY SSF46689 7 76 1.9E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04415 65125b234bfc87ff6f40cbfac81f587b 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 6.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS04415 65125b234bfc87ff6f40cbfac81f587b 205 Gene3D G3DSA:1.10.357.10 5 204 1.4E-26 T 29-03-2018 A616_RS04415 65125b234bfc87ff6f40cbfac81f587b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS04415 65125b234bfc87ff6f40cbfac81f587b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS04415 65125b234bfc87ff6f40cbfac81f587b 205 SUPERFAMILY SSF48498 124 202 2.36E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS11545 dbbcaabcd449f83aa1c539a430ac40d7 601 Pfam PF04183 IucA / IucC family 153 379 7.7E-53 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 A616_RS11545 dbbcaabcd449f83aa1c539a430ac40d7 601 Pfam PF06276 Ferric iron reductase FhuF-like transporter 410 569 6.3E-38 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 SUPERFAMILY SSF53187 2 193 3.41E-46 T 29-03-2018 A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 SUPERFAMILY SSF53187 303 377 3.41E-46 T 29-03-2018 A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 Pfam PF01546 Peptidase family M20/M25/M40 78 376 1.9E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 SUPERFAMILY SSF55031 184 286 1.06E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 Pfam PF07687 Peptidase dimerisation domain 183 272 1.8E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 Gene3D G3DSA:3.40.630.10 7 378 7.9E-49 T 29-03-2018 A616_RS03695 6bb7803fd9fa89b796aa027f2e8f6f73 378 PIRSF PIRSF037238 1 378 2.0E-124 T 29-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 2 492 3.4E-250 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 Gene3D G3DSA:3.40.50.300 211 433 0.31 T 29-03-2018 A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 SUPERFAMILY SSF52540 19 242 1.01E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 PIRSF PIRSF007466 1 492 1.2E-256 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 2.1E-225 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 Gene3D G3DSA:3.40.50.300 2 92 3.0E-5 T 29-03-2018 A616_RS13715 66d4c2eb6c27251f120bb529c0c46c3e 492 Gene3D G3DSA:3.40.50.300 93 210 0.0022 T 29-03-2018 A616_RS10675 cd76a97193236dcc9aa96580a3cc3d55 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.486 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A616_RS10675 cd76a97193236dcc9aa96580a3cc3d55 342 Gene3D G3DSA:3.40.1780.10 1 133 6.6E-41 T 29-03-2018 A616_RS10675 cd76a97193236dcc9aa96580a3cc3d55 342 Gene3D G3DSA:3.40.1780.10 173 342 1.4E-66 T 29-03-2018 A616_RS10675 cd76a97193236dcc9aa96580a3cc3d55 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 3.3E-142 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A616_RS10675 cd76a97193236dcc9aa96580a3cc3d55 342 SUPERFAMILY SSF111337 2 342 3.66E-140 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A616_RS10675 cd76a97193236dcc9aa96580a3cc3d55 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 342 3.2E-143 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A616_RS12985 7a7d80ce715b8663b3315110aac0c146 315 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 60 297 2.0E-82 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 A616_RS12985 7a7d80ce715b8663b3315110aac0c146 315 Pfam PF07136 Protein of unknown function (DUF1385) 60 300 5.6E-79 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 9 298 2.3E-123 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 SUPERFAMILY SSF53697 9 251 5.56E-71 T 29-03-2018 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 Gene3D G3DSA:1.10.8.10 273 301 1.7E-6 T 29-03-2018 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 Gene3D G3DSA:1.10.8.10 246 272 4.8E-10 T 29-03-2018 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 Gene3D G3DSA:3.40.50.10490 13 245 1.9E-52 T 29-03-2018 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 5 298 42.131 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A616_RS08830 11d0236dabb3e5f4c910a71e24b1e91d 302 Pfam PF13580 SIS domain 46 168 4.2E-11 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS28930 d4e9078c4e5984746acabc5cceeff6ae 255 Pfam PF01061 ABC-2 type transporter 17 209 2.2E-17 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A616_RS28930 d4e9078c4e5984746acabc5cceeff6ae 255 PIRSF PIRSF006648 14 245 3.3E-16 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 Pfam PF01979 Amidohydrolase family 54 400 5.9E-72 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 SUPERFAMILY SSF51338 4 56 4.88E-33 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 SUPERFAMILY SSF51338 352 427 4.88E-33 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 Gene3D G3DSA:2.30.40.10 3 70 7.9E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 427 44.594 T 29-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 Gene3D G3DSA:3.20.20.140 71 369 2.3E-58 T 29-03-2018 A616_RS07725 e6773eda90ab2b17ac159aa3b9fa1fa3 430 SUPERFAMILY SSF51556 56 352 5.02E-93 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS31030 5414c324ef2091906bda58b9ff784884 212 SMART SM00421 149 206 1.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 SUPERFAMILY SSF46894 148 211 9.86E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 SUPERFAMILY SSF52172 1 136 2.42E-24 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31030 5414c324ef2091906bda58b9ff784884 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.6E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 SMART SM00448 4 118 3.5E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 Gene3D G3DSA:3.40.50.2300 3 129 2.1E-24 T 29-03-2018 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 204 2.9E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 Pfam PF00072 Response regulator receiver domain 6 118 1.1E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31030 5414c324ef2091906bda58b9ff784884 212 Gene3D G3DSA:1.10.10.10 130 212 9.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 24 46 1.2E-7 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 179 196 1.2E-7 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 87 105 1.2E-7 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 355 378 1.2E-7 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 Pfam PF05977 Transmembrane secretion effector 20 410 3.2E-28 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 Gene3D G3DSA:1.20.1250.20 12 202 1.9E-19 T 29-03-2018 A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 SUPERFAMILY SSF103473 23 407 8.37E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS28650 9da1117cdbff1873c1259d4729b6171d 423 Gene3D G3DSA:1.20.1250.20 216 415 3.3E-14 T 29-03-2018 A616_RS06675 2b855ef9ac8f27766fef29a507be5abe 228 Gene3D G3DSA:2.40.128.110 54 228 2.0E-30 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A616_RS06675 2b855ef9ac8f27766fef29a507be5abe 228 SUPERFAMILY SSF101874 60 222 6.93E-26 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A616_RS06675 2b855ef9ac8f27766fef29a507be5abe 228 SMART SM00867 61 226 9.7E-16 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A616_RS06675 2b855ef9ac8f27766fef29a507be5abe 228 Pfam PF04264 YceI-like domain 66 223 6.3E-23 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like A616_RS27170 4418b2917e649fb3c7e1469647f632dc 366 Pfam PF03845 Spore germination protein 13 317 9.2E-27 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS27170 4418b2917e649fb3c7e1469647f632dc 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 355 5.4E-54 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26005 3b8baf05d6a1b4c7f048431194602dc0 334 Gene3D G3DSA:3.40.50.1100 144 331 1.2E-29 T 29-03-2018 A616_RS26005 3b8baf05d6a1b4c7f048431194602dc0 334 SUPERFAMILY SSF53686 4 328 1.44E-87 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS26005 3b8baf05d6a1b4c7f048431194602dc0 334 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 12 325 1.7E-96 T 29-03-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 A616_RS26005 3b8baf05d6a1b4c7f048431194602dc0 334 Gene3D G3DSA:3.40.50.1100 48 143 1.3E-30 T 29-03-2018 A616_RS26005 3b8baf05d6a1b4c7f048431194602dc0 334 PIRSF PIRSF006278 3 332 6.1E-104 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A616_RS26005 3b8baf05d6a1b4c7f048431194602dc0 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 318 2.0E-54 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 SMART SM00357 1 47 1.1E-8 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 SUPERFAMILY SSF50249 4 46 7.1E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 PRINTS PR00050 Cold shock protein signature 5 14 1.8E-10 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 PRINTS PR00050 Cold shock protein signature 20 38 1.8E-10 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 PIRSF PIRSF002599 1 47 3.3E-12 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 Gene3D G3DSA:2.40.50.140 2 47 1.1E-16 T 29-03-2018 A616_RS29415 ce0bcec802420b4ff2c89ad6fe150e12 47 Pfam PF00313 'Cold-shock' DNA-binding domain 4 46 1.8E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Gene3D G3DSA:3.40.50.980 112 138 9.5E-6 T 29-03-2018 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Pfam PF13193 AMP-binding enzyme C-terminal domain 391 468 1.4E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Gene3D G3DSA:2.30.38.10 291 375 7.3E-24 T 29-03-2018 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Gene3D G3DSA:3.40.50.980 139 290 6.6E-31 T 29-03-2018 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 SUPERFAMILY SSF56801 5 472 6.15E-99 T 29-03-2018 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Pfam PF00501 AMP-binding enzyme 124 382 8.2E-58 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Gene3D G3DSA:3.30.300.30 376 475 1.9E-20 T 29-03-2018 A616_RS28880 2fa1c757b9dd73da506553d5c78fe7d5 485 Gene3D G3DSA:3.40.50.980 3 111 1.5E-6 T 29-03-2018 A616_RS12735 d947d506415827fda7a6f55c623bcb30 236 Pfam PF00565 Staphylococcal nuclease homologue 50 156 5.9E-28 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A616_RS12735 d947d506415827fda7a6f55c623bcb30 236 SUPERFAMILY SSF50199 26 157 4.05E-35 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A616_RS12735 d947d506415827fda7a6f55c623bcb30 236 Gene3D G3DSA:3.40.10.10 163 236 2.1E-18 T 29-03-2018 IPR035451 Ada-like domain A616_RS12735 d947d506415827fda7a6f55c623bcb30 236 SMART SM00318 28 157 1.8E-32 T 29-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold A616_RS12735 d947d506415827fda7a6f55c623bcb30 236 Gene3D G3DSA:2.40.50.90 22 162 1.1E-35 T 29-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain A616_RS05315 c845938b7c1a703d70c5ef3f00e4009d 172 Pfam PF00583 Acetyltransferase (GNAT) family 48 144 1.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS05315 c845938b7c1a703d70c5ef3f00e4009d 172 SUPERFAMILY SSF55729 1 151 9.07E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS05315 c845938b7c1a703d70c5ef3f00e4009d 172 Gene3D G3DSA:3.40.630.30 2 157 2.5E-23 T 29-03-2018 A616_RS17550 59efb823448c333b9582936fd90d7999 181 Pfam PF04647 Accessory gene regulator B 8 169 4.1E-21 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 A616_RS17550 59efb823448c333b9582936fd90d7999 181 SMART SM00793 2 177 3.5E-5 T 29-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Pfam PF00395 S-layer homology domain 884 924 1.9E-8 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Pfam PF00395 S-layer homology domain 1004 1040 1.5E-5 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Pfam PF00395 S-layer homology domain 943 985 1.7E-15 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Pfam PF09992 Phosphodiester glycosidase 230 394 1.7E-28 T 29-03-2018 IPR018711 Phosphodiester glycosidase A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Gene3D G3DSA:2.60.120.430 574 751 7.4E-32 T 29-03-2018 A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Gene3D G3DSA:2.60.40.1080 398 485 0.0095 T 29-03-2018 A616_RS29985 f983709f04cf0caae15e9987319337dc 1054 Gene3D G3DSA:2.60.40.1080 486 573 1.5E-8 T 29-03-2018 A616_RS05075 52b5a7a4e68ffbaebc9e46ecdddd4814 395 Pfam PF02687 FtsX-like permease family 301 388 5.1E-15 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS05075 52b5a7a4e68ffbaebc9e46ecdddd4814 395 Pfam PF12704 MacB-like periplasmic core domain 21 238 2.5E-32 T 29-03-2018 IPR025857 MacB-like periplasmic core domain A616_RS05075 52b5a7a4e68ffbaebc9e46ecdddd4814 395 Gene3D G3DSA:1.20.1250.20 10 393 1.1E-4 T 29-03-2018 A616_RS24295 f2c1c923645505771f4fe5a0d1c1b69a 436 Pfam PF00860 Permease family 6 384 3.5E-111 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS24295 f2c1c923645505771f4fe5a0d1c1b69a 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 5 413 4.5E-131 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A616_RS24295 f2c1c923645505771f4fe5a0d1c1b69a 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 331 351 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A616_RS24295 f2c1c923645505771f4fe5a0d1c1b69a 436 TIGRFAM TIGR03173 pbuX: xanthine permease 10 415 1.8E-162 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 A616_RS26980 06d52436625edd36b4f06fe8741578e0 241 Gene3D G3DSA:3.40.50.300 1 235 5.0E-63 T 29-03-2018 A616_RS26980 06d52436625edd36b4f06fe8741578e0 241 SUPERFAMILY SSF52540 2 224 1.55E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26980 06d52436625edd36b4f06fe8741578e0 241 Pfam PF00005 ABC transporter 19 161 4.9E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS26980 06d52436625edd36b4f06fe8741578e0 241 SMART SM00382 27 209 5.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS00475 75c8d60c8c504d1dc35f53bc23ec5d30 102 Pfam PF09685 Domain of unknown function (DUF4870) 6 96 2.7E-13 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 A616_RS12675 43bec8bbd1deea279cbdf04a5fcb3894 93 SUPERFAMILY SSF140404 8 84 3.53E-33 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 A616_RS12675 43bec8bbd1deea279cbdf04a5fcb3894 93 Gene3D G3DSA:1.10.287.750 8 90 5.1E-39 T 29-03-2018 A616_RS12675 43bec8bbd1deea279cbdf04a5fcb3894 93 Pfam PF07408 Protein of unknown function (DUF1507) 10 91 5.3E-39 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 A616_RS12675 43bec8bbd1deea279cbdf04a5fcb3894 93 Hamap MF_01560 UPF0358 protein . 3 93 24.74 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 A616_RS09345 627ee5f0f041bd505da1207151709190 416 SUPERFAMILY SSF55729 3 281 8.25E-46 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS09345 627ee5f0f041bd505da1207151709190 416 Gene3D G3DSA:3.40.630.30 148 299 4.2E-31 T 29-03-2018 A616_RS09345 627ee5f0f041bd505da1207151709190 416 Gene3D G3DSA:3.30.1050.10 300 410 3.1E-21 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS09345 627ee5f0f041bd505da1207151709190 416 SUPERFAMILY SSF55718 306 416 2.02E-16 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS09345 627ee5f0f041bd505da1207151709190 416 Pfam PF13527 Acetyltransferase (GNAT) domain 3 136 1.2E-24 T 29-03-2018 A616_RS09345 627ee5f0f041bd505da1207151709190 416 Gene3D G3DSA:3.40.630.30 3 147 2.4E-13 T 29-03-2018 A616_RS09345 627ee5f0f041bd505da1207151709190 416 Pfam PF13530 Sterol carrier protein domain 180 412 2.9E-46 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Pfam PF00817 impB/mucB/samB family 12 160 8.1E-46 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Gene3D G3DSA:3.30.1490.100 253 365 3.9E-23 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Pfam PF11798 IMS family HHH motif 176 206 1.3E-5 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Hamap MF_01113 DNA polymerase IV [dinB]. 6 363 31.984 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Gene3D G3DSA:1.10.150.20 180 252 2.8E-20 T 29-03-2018 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Pfam PF11799 impB/mucB/samB family C-terminal domain 250 357 4.1E-17 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 SUPERFAMILY SSF56672 7 243 2.05E-74 T 29-03-2018 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Gene3D G3DSA:3.30.70.270 47 123 1.5E-17 T 29-03-2018 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 Gene3D G3DSA:3.30.70.270 124 179 4.7E-13 T 29-03-2018 A616_RS06495 3d2c301cb2c8b4a7d1adc33d8050f6eb 413 SUPERFAMILY SSF100879 251 351 4.71E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS02805 44298695f5ceab76b223e861fc6b171f 183 Pfam PF02525 Flavodoxin-like fold 2 176 5.5E-40 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS02805 44298695f5ceab76b223e861fc6b171f 183 SUPERFAMILY SSF52218 1 180 3.1E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS02805 44298695f5ceab76b223e861fc6b171f 183 Gene3D G3DSA:3.40.50.360 1 182 5.0E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 54 72 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 Gene3D G3DSA:1.10.10.10 1 118 9.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 80 95 2.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 2.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 47 2.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 63 2.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 SMART SM00418 30 109 2.1E-31 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 SUPERFAMILY SSF46785 24 110 3.47E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01985 f71b03b8a600648e454b05278fc72f87 121 Pfam PF01022 Bacterial regulatory protein, arsR family 37 83 5.8E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS14680 758fbf0b5e8ec573998c182dca599e51 335 SMART SM00797 24 320 6.4E-137 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A616_RS14680 758fbf0b5e8ec573998c182dca599e51 335 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 325 2.7E-98 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A616_RS14680 758fbf0b5e8ec573998c182dca599e51 335 SUPERFAMILY SSF50891 196 309 1.25E-10 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS14680 758fbf0b5e8ec573998c182dca599e51 335 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 303 1.2E-93 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A616_RS16400 71608c7d8547dccccb131f8b8e07a663 505 Gene3D G3DSA:3.40.50.1390 12 174 1.1E-26 T 29-03-2018 A616_RS16400 71608c7d8547dccccb131f8b8e07a663 505 SUPERFAMILY SSF53041 18 167 3.92E-21 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS16400 71608c7d8547dccccb131f8b8e07a663 505 SMART SM00857 17 167 8.6E-22 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS16400 71608c7d8547dccccb131f8b8e07a663 505 Pfam PF07508 Recombinase 186 280 5.7E-14 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A616_RS16400 71608c7d8547dccccb131f8b8e07a663 505 Pfam PF00239 Resolvase, N terminal domain 18 166 1.1E-18 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS07745 0fdc1e86fe135dbbd42af071db8ba1bc 303 Gene3D G3DSA:1.10.3720.10 10 303 7.8E-53 T 29-03-2018 A616_RS07745 0fdc1e86fe135dbbd42af071db8ba1bc 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 296 2.7E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07745 0fdc1e86fe135dbbd42af071db8ba1bc 303 SUPERFAMILY SSF161098 52 286 2.35E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS02895 b0b1ea5804c092d1052fac3b687a37d4 142 SUPERFAMILY SSF55874 38 132 1.64E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02895 b0b1ea5804c092d1052fac3b687a37d4 142 Gene3D G3DSA:3.30.565.10 7 140 3.5E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 SUPERFAMILY SSF53850 88 282 6.15E-30 T 29-03-2018 A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.0E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 Gene3D G3DSA:3.40.190.10 90 170 9.7E-13 T 29-03-2018 A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 Gene3D G3DSA:1.10.10.10 1 83 3.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 SUPERFAMILY SSF46785 1 109 4.99E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 Pfam PF03466 LysR substrate binding domain 88 281 1.6E-34 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS16270 d01d82d875b29fb7edad49d47be4c11d 284 Gene3D G3DSA:3.40.190.10 171 256 1.2E-10 T 29-03-2018 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 Gene3D G3DSA:3.40.50.720 2 190 2.1E-38 T 29-03-2018 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 3.4E-26 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 3.4E-26 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 PRINTS PR01713 Nucleotide sugar epimerase signature 284 301 3.4E-26 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 PRINTS PR01713 Nucleotide sugar epimerase signature 245 260 3.4E-26 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 Gene3D G3DSA:3.90.25.10 191 327 4.8E-36 T 29-03-2018 A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 SUPERFAMILY SSF51735 1 322 1.57E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS23450 5279c2d2307bba216c366aa4e100fb39 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 251 1.4E-59 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS18130 3b5d4989077c22cb1982390134664c5c 618 Gene3D G3DSA:1.25.40.10 217 499 4.2E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS18130 3b5d4989077c22cb1982390134664c5c 618 SMART SM00028 247 280 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS18130 3b5d4989077c22cb1982390134664c5c 618 SMART SM00028 315 348 0.055 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS18130 3b5d4989077c22cb1982390134664c5c 618 SUPERFAMILY SSF48452 218 360 2.11E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS18130 3b5d4989077c22cb1982390134664c5c 618 Gene3D G3DSA:1.10.287.110 1 120 6.3E-8 T 29-03-2018 IPR001623 DnaJ domain A616_RS18130 3b5d4989077c22cb1982390134664c5c 618 SUPERFAMILY SSF46565 3 50 3.53E-7 T 29-03-2018 IPR001623 DnaJ domain A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 Pfam PF01048 Phosphorylase superfamily 20 266 1.5E-59 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 21 267 2.4E-114 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 73 114 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 SUPERFAMILY SSF53167 3 268 2.23E-98 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 21 266 3.5E-111 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 PIRSF PIRSF000477 2 269 5.7E-118 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 A616_RS13350 0680c24423dedaf5b2cf0affeee7a8d7 269 Gene3D G3DSA:3.40.50.1580 1 269 5.0E-74 T 29-03-2018 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 SUPERFAMILY SSF69189 267 357 9.02E-5 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 SUPERFAMILY SSF56601 11 275 9.02E-70 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 4.8E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 112 129 4.8E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 139 152 4.8E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 Gene3D G3DSA:3.40.710.10 18 285 2.6E-59 T 29-03-2018 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 258 8.2E-62 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A616_RS13480 ab49bc57e1fda5414e497d0faa2cdd5b 389 Gene3D G3DSA:2.60.410.10 286 363 5.6E-4 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A616_RS13010 517d787b64d5d7ba1dac5d5dd5166b0f 284 SUPERFAMILY SSF81631 138 280 5.34E-57 T 29-03-2018 A616_RS13010 517d787b64d5d7ba1dac5d5dd5166b0f 284 Pfam PF04439 Streptomycin adenylyltransferase 2 278 1.8E-120 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase A616_RS13010 517d787b64d5d7ba1dac5d5dd5166b0f 284 Gene3D G3DSA:3.30.460.10 10 151 1.4E-45 T 29-03-2018 A616_RS13010 517d787b64d5d7ba1dac5d5dd5166b0f 284 PIRSF PIRSF000812 1 284 5.3E-124 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase A616_RS13010 517d787b64d5d7ba1dac5d5dd5166b0f 284 SUPERFAMILY SSF81301 1 132 1.5E-49 T 29-03-2018 A616_RS13010 517d787b64d5d7ba1dac5d5dd5166b0f 284 Gene3D G3DSA:1.20.120.330 152 281 9.7E-55 T 29-03-2018 A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 Pfam PF00578 AhpC/TSA family 4 133 9.9E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 2.1E-101 T 29-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 Gene3D G3DSA:3.40.30.10 4 154 2.7E-30 T 29-03-2018 A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 Gene3D G3DSA:3.30.1020.10 155 183 4.0E-7 T 29-03-2018 A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 4.7E-5 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 SUPERFAMILY SSF52833 2 186 5.71E-53 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS08665 fecba2fb148aa5601374137f7226c5df 187 PIRSF PIRSF000239 1 187 5.4E-48 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 Pfam PF00072 Response regulator receiver domain 7 115 2.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 Gene3D G3DSA:3.40.50.2300 1 133 5.2E-31 T 29-03-2018 A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 Gene3D G3DSA:1.10.10.10 134 232 2.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 SMART SM00448 5 116 7.1E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 SUPERFAMILY SSF52172 3 128 3.98E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 SMART SM00862 159 230 8.9E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 SUPERFAMILY SSF46894 137 230 2.72E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS03885 d59731b05f56554a0d9ab9aa883b5ce4 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 230 8.1E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS00550 a0b3b715fde851673faf23f22c79558f 329 Gene3D G3DSA:3.40.50.720 152 191 0.012 T 29-03-2018 A616_RS00550 a0b3b715fde851673faf23f22c79558f 329 Gene3D G3DSA:3.40.50.720 228 329 1.4E-4 T 29-03-2018 A616_RS31175 308b244dbcdc9293553bca5034ef35c0 218 Gene3D G3DSA:3.40.50.880 1 218 2.0E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS31175 308b244dbcdc9293553bca5034ef35c0 218 SUPERFAMILY SSF52317 1 185 4.2E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS31175 308b244dbcdc9293553bca5034ef35c0 218 Pfam PF01965 DJ-1/PfpI family 1 165 7.1E-27 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS20405 5afa10461608484354a478644a92bbc4 388 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 376 2.9E-80 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS20405 5afa10461608484354a478644a92bbc4 388 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 210 374 3.8E-30 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 338 429 8.8E-21 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 PIRSF PIRSF500136 12 444 6.5E-167 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Gene3D G3DSA:3.40.50.720 326 436 3.1E-25 T 29-03-2018 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 24 200 4.1E-47 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 221 311 6.5E-32 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Gene3D G3DSA:1.20.5.170 221 240 1.2E-10 T 29-03-2018 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 SUPERFAMILY SSF48179 220 313 2.38E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Gene3D G3DSA:3.40.50.720 10 218 4.0E-44 T 29-03-2018 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 SUPERFAMILY SSF52413 323 432 4.58E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 PIRSF PIRSF000124 22 442 5.2E-74 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 Gene3D G3DSA:1.10.1040.10 241 317 2.4E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 SUPERFAMILY SSF51735 24 213 4.67E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 SMART SM00984 338 433 2.0E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A616_RS29715 67ee300719c81e78fa4c7480a1449b8e 444 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 24 429 1.5E-138 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A616_RS24090 382a9afd208eeb5f70568b382466422e 182 Pfam PF04542 Sigma-70 region 2 25 89 4.2E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS24090 382a9afd208eeb5f70568b382466422e 182 TIGRFAM TIGR02954 Sig70_famx3: RNA polymerase sigma-70 factor, TIGR02954 family 4 171 1.4E-56 T 29-03-2018 IPR014300 RNA polymerase sigma-V type A616_RS24090 382a9afd208eeb5f70568b382466422e 182 Gene3D G3DSA:1.10.1740.10 3 117 3.2E-19 T 29-03-2018 A616_RS24090 382a9afd208eeb5f70568b382466422e 182 SUPERFAMILY SSF88659 110 170 4.11E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS24090 382a9afd208eeb5f70568b382466422e 182 Pfam PF08281 Sigma-70, region 4 114 163 2.6E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS24090 382a9afd208eeb5f70568b382466422e 182 SUPERFAMILY SSF88946 6 101 9.42E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS24090 382a9afd208eeb5f70568b382466422e 182 Gene3D G3DSA:1.10.10.10 118 174 6.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24090 382a9afd208eeb5f70568b382466422e 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 169 3.9E-23 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10125 bcb2ab3c0f0e991fed144f416d8b76c4 235 Pfam PF05050 Methyltransferase FkbM domain 38 139 7.3E-4 T 29-03-2018 IPR006342 Methyltransferase FkbM A616_RS10125 bcb2ab3c0f0e991fed144f416d8b76c4 235 Gene3D G3DSA:3.40.50.150 23 161 5.3E-4 T 29-03-2018 A616_RS12935 f020558939043ecde95a9781f681f3a8 489 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 8 487 59.646 T 29-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A616_RS12935 f020558939043ecde95a9781f681f3a8 489 Gene3D G3DSA:3.40.640.10 84 346 2.4E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS12935 f020558939043ecde95a9781f681f3a8 489 Gene3D G3DSA:3.90.1150.10 347 472 6.8E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12935 f020558939043ecde95a9781f681f3a8 489 SUPERFAMILY SSF53383 32 486 4.64E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS12935 f020558939043ecde95a9781f681f3a8 489 Pfam PF02347 Glycine cleavage system P-protein 36 310 2.9E-13 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A616_RS18430 2f707846bbdb6656b1038ab497b4af64 69 Pfam PF09360 Iron-binding zinc finger CDGSH type 13 57 3.0E-17 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A616_RS18430 2f707846bbdb6656b1038ab497b4af64 69 SMART SM00704 31 62 2.4E-9 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A616_RS23440 9c936a5165a2f8f78d10b875f2c45722 631 SUPERFAMILY SSF51735 284 546 1.75E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS23440 9c936a5165a2f8f78d10b875f2c45722 631 Pfam PF02719 Polysaccharide biosynthesis protein 285 567 5.3E-118 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A616_RS23440 9c936a5165a2f8f78d10b875f2c45722 631 Gene3D G3DSA:3.40.50.720 139 266 1.6E-29 T 29-03-2018 A616_RS23440 9c936a5165a2f8f78d10b875f2c45722 631 Pfam PF13727 CoA-binding domain 72 240 7.2E-14 T 29-03-2018 A616_RS23440 9c936a5165a2f8f78d10b875f2c45722 631 Gene3D G3DSA:3.40.50.720 278 607 1.8E-62 T 29-03-2018 A616_RS23440 9c936a5165a2f8f78d10b875f2c45722 631 SUPERFAMILY SSF53335 108 308 1.46E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 Gene3D G3DSA:3.40.50.300 12 70 8.8E-12 T 29-03-2018 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 PRINTS PR00449 Transforming protein P21 ras signature 171 193 3.9E-5 T 29-03-2018 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 PRINTS PR00449 Transforming protein P21 ras signature 133 146 3.9E-5 T 29-03-2018 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 PRINTS PR00449 Transforming protein P21 ras signature 24 45 3.9E-5 T 29-03-2018 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 Gene3D G3DSA:3.40.50.300 71 214 3.1E-17 T 29-03-2018 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 Pfam PF01926 50S ribosome-binding GTPase 25 143 1.4E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 5.3E-70 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 SUPERFAMILY SSF52540 17 194 1.14E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS10315 eaec27beac82bd380957eec4636b2b67 215 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.077 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.3E-11 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 75 90 1.3E-11 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 116 131 1.3E-11 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 42 58 1.3E-11 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 141 6.2E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 SMART SM00226 2 144 5.3E-38 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 SUPERFAMILY SSF52788 2 141 2.88E-40 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS30015 72ceaacb59153893cc6619faa8ab72e8 156 Gene3D G3DSA:3.40.50.2300 1 148 2.4E-44 T 29-03-2018 A616_RS26055 8d884650df4770fed5bd7b9b9ce13edc 275 Gene3D G3DSA:1.10.3720.10 1 263 1.4E-46 T 29-03-2018 A616_RS26055 8d884650df4770fed5bd7b9b9ce13edc 275 SUPERFAMILY SSF161098 7 275 3.27E-73 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS26055 8d884650df4770fed5bd7b9b9ce13edc 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 265 3.6E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24765 ef4516ee349637c6f0841a1bba4249aa 92 Pfam PF03466 LysR substrate binding domain 6 86 7.2E-10 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS24765 ef4516ee349637c6f0841a1bba4249aa 92 Gene3D G3DSA:3.40.190.10 2 59 3.3E-7 T 29-03-2018 A616_RS24765 ef4516ee349637c6f0841a1bba4249aa 92 SUPERFAMILY SSF53850 6 88 2.71E-10 T 29-03-2018 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 Pfam PF06580 Histidine kinase 363 441 2.2E-25 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 SMART SM00065 223 358 1.2E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 SUPERFAMILY SSF55781 233 358 4.17E-8 T 29-03-2018 IPR029016 GAF domain-like A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 Pfam PF13492 GAF domain 224 349 1.4E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 SUPERFAMILY SSF55874 417 562 4.58E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 562 3.2E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 540 3.2E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 3.2E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 562 1.9E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 SMART SM00387 452 565 1.5E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 Pfam PF07694 5TMR of 5TMR-LYT 27 191 3.7E-58 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 Gene3D G3DSA:3.30.565.10 417 565 5.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS23920 43b8836bb6afceb2c83678edddb91ff6 575 Gene3D G3DSA:3.30.450.40 121 359 2.6E-10 T 29-03-2018 IPR029016 GAF domain-like A616_RS18540 7fa686d1c1ef620e1765ce93c4809c99 415 Pfam PF13394 4Fe-4S single cluster domain 110 189 1.7E-5 T 29-03-2018 A616_RS18540 7fa686d1c1ef620e1765ce93c4809c99 415 SUPERFAMILY SSF102114 96 317 3.66E-11 T 29-03-2018 A616_RS18540 7fa686d1c1ef620e1765ce93c4809c99 415 Gene3D G3DSA:3.80.30.20 97 317 1.9E-9 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A616_RS13430 bd8326960f2f8879f6d27a455bfe499e 341 SUPERFAMILY SSF53901 50 314 1.24E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS13430 bd8326960f2f8879f6d27a455bfe499e 341 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 12 338 1.1E-149 T 29-03-2018 IPR010894 Stage V sporulation AD A616_RS13430 bd8326960f2f8879f6d27a455bfe499e 341 PIRSF PIRSF011570 7 341 7.0E-156 T 29-03-2018 IPR010894 Stage V sporulation AD A616_RS13430 bd8326960f2f8879f6d27a455bfe499e 341 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 12 338 2.4E-153 T 29-03-2018 IPR010894 Stage V sporulation AD A616_RS13430 bd8326960f2f8879f6d27a455bfe499e 341 Gene3D G3DSA:3.40.47.10 4 183 8.6E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 SUPERFAMILY SSF55874 161 324 3.67E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 216 323 2.6E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 Gene3D G3DSA:3.30.565.10 184 332 2.8E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 SMART SM00388 113 170 1.8E-4 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 SMART SM00387 215 327 1.1E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 Gene3D G3DSA:1.10.287.130 101 183 5.2E-4 T 29-03-2018 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 305 1.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 324 1.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 1.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 1.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS03240 c7570ba686a1c6443a2525bcca8f0ac0 338 SUPERFAMILY SSF47384 99 168 4.12E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS12470 b98c9c8565681af7fd9663fd2bf8cafa 639 Gene3D G3DSA:3.60.10.10 331 636 5.2E-31 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS12470 b98c9c8565681af7fd9663fd2bf8cafa 639 Gene3D G3DSA:2.40.50.200 36 167 3.3E-4 T 29-03-2018 A616_RS12470 b98c9c8565681af7fd9663fd2bf8cafa 639 SUPERFAMILY SSF56219 331 635 1.24E-31 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS20865 cea04a340b65d644ae75b8e5e9c9ee90 310 SUPERFAMILY SSF46785 8 81 3.13E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20865 cea04a340b65d644ae75b8e5e9c9ee90 310 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 5.9E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS20865 cea04a340b65d644ae75b8e5e9c9ee90 310 Gene3D G3DSA:1.10.10.10 3 79 7.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20865 cea04a340b65d644ae75b8e5e9c9ee90 310 SMART SM00345 18 77 4.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS04305 4596eca1e7b820ece07396735d1ae5d2 403 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 399 3.1E-103 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 A616_RS04305 4596eca1e7b820ece07396735d1ae5d2 403 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 234 379 1.8E-24 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 A616_RS04305 4596eca1e7b820ece07396735d1ae5d2 403 Gene3D G3DSA:3.40.50.2000 240 385 5.0E-40 T 29-03-2018 A616_RS04305 4596eca1e7b820ece07396735d1ae5d2 403 Gene3D G3DSA:3.40.50.2000 3 239 2.7E-28 T 29-03-2018 A616_RS04305 4596eca1e7b820ece07396735d1ae5d2 403 SUPERFAMILY SSF53756 3 397 3.4E-80 T 29-03-2018 A616_RS11285 7ab469495622eed56044fe39ae4cd084 91 Gene3D G3DSA:1.20.58.110 1 91 1.5E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS11285 7ab469495622eed56044fe39ae4cd084 91 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.684 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS11285 7ab469495622eed56044fe39ae4cd084 91 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 15 88 3.0E-19 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS11285 7ab469495622eed56044fe39ae4cd084 91 SUPERFAMILY SSF46992 3 86 1.96E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS11285 7ab469495622eed56044fe39ae4cd084 91 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 2.1E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS11285 7ab469495622eed56044fe39ae4cd084 91 Pfam PF01649 Ribosomal protein S20 2 84 5.0E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 Gene3D G3DSA:3.40.50.1980 50 177 4.5E-30 T 29-03-2018 A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 Gene3D G3DSA:3.40.50.1980 178 339 1.7E-23 T 29-03-2018 A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 SUPERFAMILY SSF53807 52 333 7.46E-55 T 29-03-2018 A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 318 331 1.5E-7 T 29-03-2018 IPR008091 Ferrichrome-binding periplasmic protein A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 87 105 1.5E-7 T 29-03-2018 IPR008091 Ferrichrome-binding periplasmic protein A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 119 134 1.5E-7 T 29-03-2018 IPR008091 Ferrichrome-binding periplasmic protein A616_RS04535 dacddb8bb216cdc7ab96675ed88e27a9 339 Pfam PF01497 Periplasmic binding protein 70 315 2.8E-29 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS19460 2d0e93178bc172401c962446b767595d 316 SUPERFAMILY SSF52540 56 301 5.63E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19460 2d0e93178bc172401c962446b767595d 316 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 97 227 1.7E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 Gene3D G3DSA:3.40.50.300 31 228 4.9E-24 T 29-03-2018 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 216 235 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 96 111 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 276 288 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 178 190 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 56 70 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 148 167 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 199 216 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 PRINTS PR00819 CbxX/CfqX superfamily signature 134 148 5.8E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 A616_RS19460 2d0e93178bc172401c962446b767595d 316 SMART SM00382 93 231 8.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS16765 507981d49b2b36041a8b378718725f77 170 Pfam PF02592 Putative vitamin uptake transporter 74 158 1.6E-8 T 29-03-2018 IPR003744 Queuosine precursor transporter A616_RS27025 3636ebcad8f599a3f002ef5cbdaddb60 110 Gene3D G3DSA:1.20.1260.10 1 82 5.9E-10 T 29-03-2018 IPR012347 Ferritin-related A616_RS27025 3636ebcad8f599a3f002ef5cbdaddb60 110 Pfam PF07875 Coat F domain 24 86 6.0E-24 T 29-03-2018 IPR012851 Spore coat protein CotF-like A616_RS15130 4ba469003c2c324c9e3e3a7d3c491081 288 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 84 8.1E-22 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A616_RS15130 4ba469003c2c324c9e3e3a7d3c491081 288 SUPERFAMILY SSF53697 100 285 2.64E-48 T 29-03-2018 A616_RS15130 4ba469003c2c324c9e3e3a7d3c491081 288 Gene3D G3DSA:1.10.10.10 8 101 1.5E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15130 4ba469003c2c324c9e3e3a7d3c491081 288 SUPERFAMILY SSF46689 10 84 1.06E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS15130 4ba469003c2c324c9e3e3a7d3c491081 288 Pfam PF01380 SIS domain 134 262 1.1E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS15130 4ba469003c2c324c9e3e3a7d3c491081 288 Gene3D G3DSA:3.40.50.10490 102 288 4.7E-41 T 29-03-2018 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 SUPERFAMILY SSF53901 16 117 1.6E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 SUPERFAMILY SSF53901 187 391 1.6E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 Pfam PF00108 Thiolase, N-terminal domain 7 191 9.0E-14 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 Gene3D G3DSA:3.40.47.10 249 373 1.7E-17 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 PIRSF PIRSF000429 1 392 2.1E-58 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 Gene3D G3DSA:3.40.47.10 2 243 2.8E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 Pfam PF02803 Thiolase, C-terminal domain 271 363 6.2E-8 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A616_RS15380 a6e4b6efb13f786862ef5d7c15fba3ff 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 78 96 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A616_RS22610 c20859b26994032911b964589dfa8bcf 157 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 32 149 2.2E-39 T 29-03-2018 IPR005562 SpoVA A616_RS22610 c20859b26994032911b964589dfa8bcf 157 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 153 7.0E-61 T 29-03-2018 IPR014203 Sporulation stage V, protein AC A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 Pfam PF07690 Major Facilitator Superfamily 14 269 1.5E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 Gene3D G3DSA:1.20.1250.20 4 196 1.5E-43 T 29-03-2018 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 Gene3D G3DSA:1.20.1250.20 197 406 1.2E-24 T 29-03-2018 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 PRINTS PR01035 Tetracycline resistance protein signature 20 36 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 PRINTS PR01035 Tetracycline resistance protein signature 282 303 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 PRINTS PR01035 Tetracycline resistance protein signature 135 157 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 PRINTS PR01035 Tetracycline resistance protein signature 163 183 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 PRINTS PR01035 Tetracycline resistance protein signature 342 365 2.8E-19 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS27855 1d45a3b93206386eae56cd2b24b6422f 409 SUPERFAMILY SSF103473 10 395 3.27E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS04250 3256cb3ac998693ff01ce0da2495cd1b 139 SUPERFAMILY SSF53098 9 131 5.92E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS04250 3256cb3ac998693ff01ce0da2495cd1b 139 Pfam PF13333 Integrase core domain 80 135 4.0E-17 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A616_RS04250 3256cb3ac998693ff01ce0da2495cd1b 139 Gene3D G3DSA:3.30.420.10 3 137 9.4E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS32270 e0a781b3b4e6415d56af4c7dfb636e2d 187 PRINTS PR01837 MgtC/SapB protein signature 106 130 5.4E-27 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS32270 e0a781b3b4e6415d56af4c7dfb636e2d 187 PRINTS PR01837 MgtC/SapB protein signature 24 43 5.4E-27 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS32270 e0a781b3b4e6415d56af4c7dfb636e2d 187 PRINTS PR01837 MgtC/SapB protein signature 79 101 5.4E-27 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS32270 e0a781b3b4e6415d56af4c7dfb636e2d 187 Pfam PF02308 MgtC family 21 148 3.0E-35 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS29380 3a3061e56cf71dcdc37929cd3b0cb5c3 89 Pfam PF03795 YCII-related domain 1 81 2.5E-14 T 29-03-2018 IPR005545 YCII-related A616_RS29380 3a3061e56cf71dcdc37929cd3b0cb5c3 89 Gene3D G3DSA:3.30.70.1060 2 84 5.0E-20 T 29-03-2018 A616_RS29380 3a3061e56cf71dcdc37929cd3b0cb5c3 89 SUPERFAMILY SSF54909 1 83 2.52E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 Gene3D G3DSA:3.30.390.10 6 130 3.4E-22 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 Gene3D G3DSA:3.20.20.120 131 367 6.5E-41 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 SUPERFAMILY SSF54826 12 126 6.91E-22 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 43 125 6.0E-6 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 SMART SM00922 149 246 1.1E-8 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 Pfam PF13378 Enolase C-terminal domain-like 157 370 5.2E-52 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS21190 93fde44bebcd1db8d7b98dcefddb324f 383 SUPERFAMILY SSF51604 113 379 5.85E-52 T 29-03-2018 IPR029065 Enolase C-terminal domain-like A616_RS14390 d7b7bb869257ffe31e07dc12e1255350 138 SUPERFAMILY SSF54637 3 135 6.28E-45 T 29-03-2018 IPR029069 HotDog domain A616_RS14390 d7b7bb869257ffe31e07dc12e1255350 138 Gene3D G3DSA:3.10.129.10 1 132 8.0E-41 T 29-03-2018 A616_RS14390 d7b7bb869257ffe31e07dc12e1255350 138 Pfam PF01575 MaoC like domain 7 106 6.0E-27 T 29-03-2018 IPR002539 MaoC-like domain A616_RS24115 f09f383be79da318d4c174f26daf3608 540 SUPERFAMILY SSF110921 404 513 2.75E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 4 523 7.6E-234 T 29-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 Pfam PF08502 LeuA allosteric (dimerisation) domain 376 516 1.4E-29 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 203 216 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 SUPERFAMILY SSF51569 1 292 5.68E-86 T 29-03-2018 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 Pfam PF00682 HMGL-like 4 275 1.8E-49 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 SMART SM00917 375 517 9.4E-38 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 Gene3D G3DSA:3.30.70.360 417 519 0.003 T 29-03-2018 A616_RS24115 f09f383be79da318d4c174f26daf3608 540 Gene3D G3DSA:3.20.20.70 1 351 2.4E-106 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS05410 847fad257a8c30b4b0afa400f3b41423 120 Gene3D G3DSA:3.10.180.10 4 118 5.2E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS05410 847fad257a8c30b4b0afa400f3b41423 120 SUPERFAMILY SSF54593 1 115 2.89E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS05410 847fad257a8c30b4b0afa400f3b41423 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 114 1.3E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS19955 d728dfa0566266327a1165d05d2d48ac 260 Pfam PF01311 Bacterial export proteins, family 1 9 244 1.1E-70 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A616_RS19955 d728dfa0566266327a1165d05d2d48ac 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 178 200 2.1E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A616_RS19955 d728dfa0566266327a1165d05d2d48ac 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 75 94 2.1E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A616_RS19955 d728dfa0566266327a1165d05d2d48ac 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 17 38 2.1E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A616_RS19955 d728dfa0566266327a1165d05d2d48ac 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 200 219 2.1E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A616_RS19955 d728dfa0566266327a1165d05d2d48ac 260 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 253 1.4E-61 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 A616_RS24510 bb205f0d3073758b1c7849d75810495d 192 Pfam PF05076 Suppressor of fused protein (SUFU) 35 189 3.7E-26 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 A616_RS24510 bb205f0d3073758b1c7849d75810495d 192 ProDom PD105609 PLASMID YQCF RSP1132 10 191 1.0E-48 T 29-03-2018 A616_RS08085 aacfbc08ba40c961787d87c9b722d117 187 SUPERFAMILY SSF53955 34 185 4.5E-45 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS08085 aacfbc08ba40c961787d87c9b722d117 187 Pfam PF01464 Transglycosylase SLT domain 41 154 2.2E-32 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 A616_RS08085 aacfbc08ba40c961787d87c9b722d117 187 Gene3D G3DSA:1.10.530.10 30 182 8.6E-40 T 29-03-2018 A616_RS28165 05c19d88bdc062e180082e728c2d50f9 290 Pfam PF03413 Peptidase propeptide and YPEB domain 181 239 1.2E-8 T 29-03-2018 IPR025711 PepSY domain A616_RS28165 05c19d88bdc062e180082e728c2d50f9 290 Pfam PF03413 Peptidase propeptide and YPEB domain 34 89 1.8E-7 T 29-03-2018 IPR025711 PepSY domain A616_RS28165 05c19d88bdc062e180082e728c2d50f9 290 Gene3D G3DSA:3.10.450.40 33 91 1.6E-7 T 29-03-2018 A616_RS28165 05c19d88bdc062e180082e728c2d50f9 290 Gene3D G3DSA:3.10.450.40 182 242 2.4E-11 T 29-03-2018 A616_RS20985 65e0dfe689f2f0ee70ffc64fc0e1db2b 365 Gene3D G3DSA:3.40.50.720 1 161 3.6E-6 T 29-03-2018 A616_RS20985 65e0dfe689f2f0ee70ffc64fc0e1db2b 365 SUPERFAMILY SSF51735 5 95 4.29E-8 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 Pfam PF00455 DeoR C terminal sensor domain 78 239 1.2E-42 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 Pfam PF08220 DeoR-like helix-turn-helix domain 8 60 3.2E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 SUPERFAMILY SSF46785 6 65 2.19E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 SMART SM00420 8 60 7.5E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 Gene3D G3DSA:1.10.10.10 5 66 7.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 SUPERFAMILY SSF100950 78 241 5.62E-29 T 29-03-2018 A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 SMART SM01134 75 241 1.4E-55 T 29-03-2018 A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 Gene3D G3DSA:3.40.50.1360 75 245 2.9E-34 T 29-03-2018 A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 2.9E-6 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS24675 677c486d315ec1688f7b3a96e479c056 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 2.9E-6 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS02660 1d1aaebc28a4f38d547656f0fea0054d 570 Pfam PF13490 Putative zinc-finger 8 36 2.8E-5 T 29-03-2018 IPR027383 Putative zinc-finger A616_RS02660 1d1aaebc28a4f38d547656f0fea0054d 570 Pfam PF13786 Domain of unknown function (DUF4179) 97 205 3.6E-15 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS02660 1d1aaebc28a4f38d547656f0fea0054d 570 Gene3D G3DSA:2.60.40.1640 318 488 1.0E-10 T 29-03-2018 A616_RS02660 1d1aaebc28a4f38d547656f0fea0054d 570 Gene3D G3DSA:2.60.40.1630 150 313 8.3E-20 T 29-03-2018 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 184 7.2E-46 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 419 1.4E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 9 34 1.4E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 421 450 1.4E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 Gene3D G3DSA:1.20.120.30 26 185 3.5E-17 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 SMART SM00283 294 569 3.3E-88 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 Pfam PF00672 HAMP domain 213 261 4.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 Gene3D G3DSA:1.10.287.950 309 506 5.1E-53 T 29-03-2018 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 Gene3D G3DSA:1.10.287.950 507 570 6.2E-5 T 29-03-2018 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 SUPERFAMILY SSF58104 300 569 4.97E-77 T 29-03-2018 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 SUPERFAMILY SSF58104 233 267 4.97E-77 T 29-03-2018 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 SMART SM00304 213 265 1.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS18395 2e3d079bae6d6d2f4ed5849ce4bbc046 570 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 339 517 4.3E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 249 5.3E-98 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 1.7E-96 T 29-03-2018 A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 SUPERFAMILY SSF56219 1 249 2.36E-80 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 1.1E-24 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS01850 67eaf291a22dcf037bee2de41ef1b39f 253 Gene3D G3DSA:3.60.10.10 1 250 7.4E-55 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A616_RS12085 eb2973eb4af2724b116081bd014a94d0 146 Pfam PF04134 Protein of unknown function, DUF393 19 129 3.6E-34 T 29-03-2018 IPR007263 Protein of unknown function DUF393 A616_RS18285 2a3ff47016d88f03d6d71fe9ad4c2752 224 Pfam PF01596 O-methyltransferase 34 204 3.6E-41 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A616_RS18285 2a3ff47016d88f03d6d71fe9ad4c2752 224 SUPERFAMILY SSF53335 10 220 9.53E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS18285 2a3ff47016d88f03d6d71fe9ad4c2752 224 Gene3D G3DSA:3.40.50.150 1 222 3.1E-37 T 29-03-2018 A616_RS10420 ce39a801a5a71cf1edcd5b9430bbe9bc 331 Gene3D G3DSA:3.90.1200.10 108 330 2.0E-16 T 29-03-2018 A616_RS10420 ce39a801a5a71cf1edcd5b9430bbe9bc 331 Gene3D G3DSA:3.30.200.20 1 94 5.2E-5 T 29-03-2018 A616_RS10420 ce39a801a5a71cf1edcd5b9430bbe9bc 331 SUPERFAMILY SSF56112 7 328 7.82E-24 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS24875 a5e50320b5c4418ef35796ce718cac6c 493 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 24 446 1.3E-73 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 A616_RS23430 7e662dffaebc032a56a902309f346f5c 250 Pfam PF13807 G-rich domain on putative tyrosine kinase 143 196 9.9E-7 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain A616_RS23430 7e662dffaebc032a56a902309f346f5c 250 Gene3D G3DSA:3.30.1890.10 37 164 6.4E-9 T 29-03-2018 A616_RS23430 7e662dffaebc032a56a902309f346f5c 250 Pfam PF02706 Chain length determinant protein 3 93 7.9E-17 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 47 2.0E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 2.0E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 340 346 2.0E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 24 36 2.0E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 53 65 2.0E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 370 382 2.0E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 29 46 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 407 538 7.7E-24 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 Gene3D G3DSA:3.50.50.60 1 421 6.5E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 Pfam PF01266 FAD dependent oxidoreductase 25 351 2.9E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 SUPERFAMILY SSF54373 253 346 5.1E-12 T 29-03-2018 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 SUPERFAMILY SSF51905 14 90 5.77E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 SUPERFAMILY SSF51905 119 128 5.77E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS27680 670dc7f3135267a4dde8b82a0136a136 556 SUPERFAMILY SSF51905 161 241 5.77E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS01380 9cc649a380d6a2cb8cc43eeb483575a2 311 Pfam PF00892 EamA-like transporter family 10 139 8.2E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS01380 9cc649a380d6a2cb8cc43eeb483575a2 311 Pfam PF00892 EamA-like transporter family 151 288 2.2E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS01380 9cc649a380d6a2cb8cc43eeb483575a2 311 SUPERFAMILY SSF103481 214 289 1.57E-12 T 29-03-2018 A616_RS01380 9cc649a380d6a2cb8cc43eeb483575a2 311 SUPERFAMILY SSF103481 40 142 7.19E-17 T 29-03-2018 A616_RS18655 f0f3ead860ed1b420aac74dd70705af2 207 Pfam PF02581 Thiamine monophosphate synthase 9 184 3.0E-42 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS18655 f0f3ead860ed1b420aac74dd70705af2 207 Gene3D G3DSA:3.20.20.70 2 202 1.9E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS18655 f0f3ead860ed1b420aac74dd70705af2 207 SUPERFAMILY SSF51391 6 204 8.37E-48 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 Pfam PF00005 ABC transporter 326 448 3.0E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 Pfam PF00005 ABC transporter 20 150 1.7E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 SUPERFAMILY SSF52540 2 194 1.53E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 SUPERFAMILY SSF52540 317 494 8.26E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 Gene3D G3DSA:3.40.50.300 1 301 8.3E-41 T 29-03-2018 A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 Gene3D G3DSA:3.40.50.300 302 498 2.3E-28 T 29-03-2018 A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 SMART SM00382 28 195 5.7E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 SMART SM00382 334 485 1.7E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15620 88eb715e3ca275bc3de58cbbbc03337c 499 ProSitePatterns PS00211 ABC transporters family signature. 421 435 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS24225 e20c1077df6b9c4873b509a22111ea85 174 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 8 171 4.2E-47 T 29-03-2018 IPR006286 Peptidase C56, PfpI A616_RS24225 e20c1077df6b9c4873b509a22111ea85 174 SUPERFAMILY SSF52317 6 172 1.75E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS24225 e20c1077df6b9c4873b509a22111ea85 174 Pfam PF01965 DJ-1/PfpI family 6 168 3.0E-43 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS24225 e20c1077df6b9c4873b509a22111ea85 174 Gene3D G3DSA:3.40.50.880 2 174 8.5E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS24610 50d750b60052a82a4fd77ff2101581c3 308 Gene3D G3DSA:3.30.200.20 3 153 1.3E-24 T 29-03-2018 A616_RS24610 50d750b60052a82a4fd77ff2101581c3 308 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 159 171 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A616_RS24610 50d750b60052a82a4fd77ff2101581c3 308 Gene3D G3DSA:1.10.510.10 154 306 4.7E-29 T 29-03-2018 A616_RS24610 50d750b60052a82a4fd77ff2101581c3 308 SUPERFAMILY SSF56112 12 290 5.13E-49 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS24610 50d750b60052a82a4fd77ff2101581c3 308 Pfam PF00069 Protein kinase domain 75 238 2.7E-33 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS24610 50d750b60052a82a4fd77ff2101581c3 308 SMART SM00220 20 294 1.7E-23 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A616_RS08605 fe68ee425f60d0b42f98781fc1289e46 435 Pfam PF01098 Cell cycle protein 95 424 8.4E-28 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 SMART SM00862 150 226 1.7E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 Pfam PF00072 Response regulator receiver domain 5 113 1.1E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 SUPERFAMILY SSF52172 1 129 1.71E-43 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 SUPERFAMILY SSF46894 127 227 2.75E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 SMART SM00448 2 112 3.0E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 Gene3D G3DSA:3.40.50.2300 1 117 1.1E-38 T 29-03-2018 A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 Gene3D G3DSA:1.10.10.10 118 232 8.6E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS32125 fb52a60b4bd31bd975241ba759c2f042 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 1.6E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 Gene3D G3DSA:1.20.1260.10 4 150 4.0E-51 T 29-03-2018 IPR012347 Ferritin-related A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 31 47 1.5E-15 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 126 144 1.5E-15 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 55 71 1.5E-15 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 SUPERFAMILY SSF47240 9 149 3.61E-47 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 PIRSF PIRSF005900 1 150 1.4E-50 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 ProSitePatterns PS00818 Dps protein family signature 1. 31 47 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A616_RS07535 c0c3cae7ff882c481696dc979f96683d 150 Pfam PF00210 Ferritin-like domain 12 150 1.7E-33 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A616_RS09755 9174c0723bf4be362029361634be2c34 237 Pfam PF00005 ABC transporter 18 162 8.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09755 9174c0723bf4be362029361634be2c34 237 Gene3D G3DSA:3.40.50.300 1 235 1.3E-59 T 29-03-2018 A616_RS09755 9174c0723bf4be362029361634be2c34 237 SMART SM00382 26 233 5.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09755 9174c0723bf4be362029361634be2c34 237 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS09755 9174c0723bf4be362029361634be2c34 237 SUPERFAMILY SSF52540 2 233 1.07E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS09755 9174c0723bf4be362029361634be2c34 237 PIRSF PIRSF039137 1 235 3.5E-108 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 A616_RS08400 d4b46999575e526d147608cfaafb32de 167 Pfam PF05099 Tellurite resistance protein TerB 9 133 3.5E-6 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal A616_RS08400 d4b46999575e526d147608cfaafb32de 167 SUPERFAMILY SSF158682 3 137 1.7E-15 T 29-03-2018 A616_RS08400 d4b46999575e526d147608cfaafb32de 167 Gene3D G3DSA:1.10.3680.10 1 141 6.4E-17 T 29-03-2018 IPR029024 TerB-like A616_RS21410 56b4ea0cec472741070097a0cf261e42 155 PIRSF PIRSF037732 1 154 3.8E-74 T 29-03-2018 IPR017274 Putative N-acetyltransferase YlbP A616_RS21410 56b4ea0cec472741070097a0cf261e42 155 SUPERFAMILY SSF55729 15 140 4.61E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS21410 56b4ea0cec472741070097a0cf261e42 155 Gene3D G3DSA:3.40.630.30 1 155 9.3E-26 T 29-03-2018 A616_RS21410 56b4ea0cec472741070097a0cf261e42 155 Hamap MF_00824 Uncharacterized N-acetyltransferase . 1 148 39.42 T 29-03-2018 IPR017274 Putative N-acetyltransferase YlbP A616_RS21410 56b4ea0cec472741070097a0cf261e42 155 Pfam PF00583 Acetyltransferase (GNAT) family 29 106 7.9E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS03905 23ed83008095cee09ac2561ac9b555c2 566 Gene3D G3DSA:2.60.40.1630 145 305 8.2E-21 T 29-03-2018 A616_RS03905 23ed83008095cee09ac2561ac9b555c2 566 Gene3D G3DSA:2.60.40.1640 462 562 1.5E-4 T 29-03-2018 A616_RS03905 23ed83008095cee09ac2561ac9b555c2 566 Gene3D G3DSA:2.60.40.1640 310 461 2.3E-6 T 29-03-2018 A616_RS03905 23ed83008095cee09ac2561ac9b555c2 566 Pfam PF13786 Domain of unknown function (DUF4179) 99 201 7.2E-18 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS06135 4ed43a61356d16bb81b295966487e699 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 154 1.1E-58 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A616_RS06135 4ed43a61356d16bb81b295966487e699 156 PIRSF PIRSF029256 2 156 1.3E-61 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A616_RS06135 4ed43a61356d16bb81b295966487e699 156 Pfam PF00588 SpoU rRNA Methylase family 3 144 2.1E-32 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A616_RS06135 4ed43a61356d16bb81b295966487e699 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 153 33.165 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A616_RS06135 4ed43a61356d16bb81b295966487e699 156 SUPERFAMILY SSF75217 2 154 2.29E-41 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases A616_RS06135 4ed43a61356d16bb81b295966487e699 156 Gene3D G3DSA:3.40.1280.10 1 155 5.5E-37 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 Pfam PF12833 Helix-turn-helix domain 201 279 8.8E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 SUPERFAMILY SSF46689 178 228 3.05E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 Gene3D G3DSA:1.10.10.60 167 228 7.4E-13 T 29-03-2018 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 232 274 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 278 6.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 262 6.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 SMART SM00342 195 278 2.7E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 SUPERFAMILY SSF46689 231 281 2.46E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31925 18815f3bea786fffa7bfdf75a2877278 286 Gene3D G3DSA:1.10.10.60 229 286 1.1E-12 T 29-03-2018 A616_RS00565 93ad05e106dc37d4d7b2493a3fbebd03 213 SUPERFAMILY SSF52540 7 207 1.82E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00565 93ad05e106dc37d4d7b2493a3fbebd03 213 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 8 203 1.5E-61 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A616_RS00565 93ad05e106dc37d4d7b2493a3fbebd03 213 Pfam PF02223 Thymidylate kinase 14 203 4.3E-55 T 29-03-2018 A616_RS00565 93ad05e106dc37d4d7b2493a3fbebd03 213 ProSitePatterns PS01331 Thymidylate kinase signature. 99 111 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A616_RS00565 93ad05e106dc37d4d7b2493a3fbebd03 213 Gene3D G3DSA:3.40.50.300 7 209 2.2E-52 T 29-03-2018 A616_RS00565 93ad05e106dc37d4d7b2493a3fbebd03 213 Hamap MF_00165 Thymidylate kinase [tmk]. 10 213 31.525 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 SUPERFAMILY SSF110455 1 114 1.83E-36 T 29-03-2018 A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 Pfam PF13331 Domain of unknown function (DUF4093) 90 174 5.6E-28 T 29-03-2018 IPR025156 Ribonuclease M5, C-terminal domain A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 Gene3D G3DSA:3.40.1360.20 1 123 1.3E-22 T 29-03-2018 A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 176 32.012 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 171 5.9E-54 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 SMART SM00493 4 77 1.2E-7 T 29-03-2018 IPR006171 TOPRIM domain A616_RS00635 65a1e4895dd2e60308eb3184d216419f 182 Pfam PF13662 Toprim domain 4 69 2.8E-6 T 29-03-2018 IPR006171 TOPRIM domain A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Gene3D G3DSA:3.40.50.620 211 386 2.7E-12 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Gene3D G3DSA:3.40.50.620 620 768 3.0E-14 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 SUPERFAMILY SSF52402 249 374 4.6E-10 T 29-03-2018 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Pfam PF00582 Universal stress protein family 268 367 1.5E-5 T 29-03-2018 IPR006016 UspA GO:0006950 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Pfam PF00582 Universal stress protein family 646 768 3.6E-5 T 29-03-2018 IPR006016 UspA GO:0006950 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 21 227 1.5E-57 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 415 624 1.3E-96 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 SUPERFAMILY SSF52540 152 202 2.25E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 SUPERFAMILY SSF52540 27 119 2.25E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 SUPERFAMILY SSF52540 421 539 1.3E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Gene3D G3DSA:3.40.50.300 21 149 6.0E-14 T 29-03-2018 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 Gene3D G3DSA:3.40.50.300 415 549 1.2E-23 T 29-03-2018 A616_RS02290 c94a6f9f1ad6ace617777e356bf46c88 776 SUPERFAMILY SSF52402 646 768 2.85E-11 T 29-03-2018 A616_RS14580 93d9a7c4c2b370f6bddc82befa3cceac 109 Pfam PF01638 HxlR-like helix-turn-helix 14 102 1.2E-38 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS14580 93d9a7c4c2b370f6bddc82befa3cceac 109 Gene3D G3DSA:1.10.10.10 12 107 3.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14580 93d9a7c4c2b370f6bddc82befa3cceac 109 SUPERFAMILY SSF46785 3 102 4.51E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31610 2aa3caed6902f2121747d36d183175bd 322 Gene3D G3DSA:3.40.50.1980 35 162 7.4E-27 T 29-03-2018 A616_RS31610 2aa3caed6902f2121747d36d183175bd 322 Gene3D G3DSA:3.40.50.1980 163 322 1.3E-36 T 29-03-2018 A616_RS31610 2aa3caed6902f2121747d36d183175bd 322 SUPERFAMILY SSF53807 46 302 6.28E-65 T 29-03-2018 A616_RS31610 2aa3caed6902f2121747d36d183175bd 322 Pfam PF01497 Periplasmic binding protein 67 289 3.9E-34 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 SUPERFAMILY SSF46894 124 223 1.42E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 SMART SM00448 2 112 5.1E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 Pfam PF00072 Response regulator receiver domain 4 113 3.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 Gene3D G3DSA:3.40.50.2300 1 122 3.2E-34 T 29-03-2018 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 SMART SM00862 148 223 8.6E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 Gene3D G3DSA:1.10.10.10 123 225 2.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 3.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05435 4ed8fa1c570b08e9bbe168dae10aeb19 225 SUPERFAMILY SSF52172 3 127 4.27E-39 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS01945 434b9e96bd6357d0f37ccd3b5751142c 167 Pfam PF05163 DinB family 5 165 1.1E-36 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB A616_RS01945 434b9e96bd6357d0f37ccd3b5751142c 167 SUPERFAMILY SSF109854 8 162 4.58E-30 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS01945 434b9e96bd6357d0f37ccd3b5751142c 167 Gene3D G3DSA:1.20.120.450 1 167 2.8E-27 T 29-03-2018 A616_RS30940 694eea48bc4002d08bb587bb539025ea 474 Gene3D G3DSA:3.40.309.10 265 456 4.8E-62 T 29-03-2018 A616_RS30940 694eea48bc4002d08bb587bb539025ea 474 Pfam PF00171 Aldehyde dehydrogenase family 14 469 3.1E-152 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS30940 694eea48bc4002d08bb587bb539025ea 474 SUPERFAMILY SSF53720 4 473 3.8E-143 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS30940 694eea48bc4002d08bb587bb539025ea 474 Gene3D G3DSA:3.40.605.10 1 264 5.6E-81 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 Pfam PF01470 Pyroglutamyl peptidase 3 202 1.8E-84 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 214 3.7E-88 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 Gene3D G3DSA:3.40.630.20 1 215 1.2E-66 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 PIRSF PIRSF015592 1 213 1.5E-87 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 40.826 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 SUPERFAMILY SSF53182 1 212 1.05E-74 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 1.1E-50 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 1.1E-50 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 1.1E-50 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 1.1E-50 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A616_RS14670 d617fb51e97d59c5459b6a5a66d9d013 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 1.1E-50 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 A616_RS21720 016de698f9affa163844ed9d11dab7f3 122 SUPERFAMILY SSF54593 7 119 1.65E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS21720 016de698f9affa163844ed9d11dab7f3 122 Gene3D G3DSA:3.10.180.10 4 119 8.3E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS21720 016de698f9affa163844ed9d11dab7f3 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 115 1.0E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 SUPERFAMILY SSF56300 240 502 6.01E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 Gene3D G3DSA:3.60.21.10 237 497 3.2E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 Pfam PF02368 Bacterial Ig-like domain (group 2) 1119 1201 3.3E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 Pfam PF00149 Calcineurin-like phosphoesterase 246 442 2.2E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 SMART SM00635 1207 1295 5.8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 SMART SM00635 1117 1202 0.048 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 Gene3D G3DSA:2.60.40.1080 1124 1205 2.2E-8 T 29-03-2018 A616_RS31565 18f8d0eda8bb528eb228f14e496d1bf3 1298 Gene3D G3DSA:2.60.40.1080 1206 1298 2.0E-7 T 29-03-2018 A616_RS11645 90c2a15acb225362692a88301ca7bb02 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 3.2E-44 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 A616_RS11645 90c2a15acb225362692a88301ca7bb02 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 7.2E-16 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A616_RS11645 90c2a15acb225362692a88301ca7bb02 132 SUPERFAMILY SSF53927 1 130 1.35E-46 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS11645 90c2a15acb225362692a88301ca7bb02 132 Gene3D G3DSA:3.40.140.10 1 132 2.2E-49 T 29-03-2018 A616_RS11645 90c2a15acb225362692a88301ca7bb02 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A616_RS03270 e33407e178ef5cf035cd395780547a55 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 6.1E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS03270 e33407e178ef5cf035cd395780547a55 318 Gene3D G3DSA:1.10.3720.10 3 300 8.0E-44 T 29-03-2018 A616_RS03270 e33407e178ef5cf035cd395780547a55 318 SUPERFAMILY SSF161098 89 297 6.54E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS30865 0292d2e5f4694bbb617fb7dd91924355 281 Gene3D G3DSA:3.80.10.10 208 273 4.0E-6 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A616_RS30865 0292d2e5f4694bbb617fb7dd91924355 281 Pfam PF12799 Leucine Rich repeats (2 copies) 159 195 3.4E-7 T 29-03-2018 IPR025875 Leucine rich repeat 4 A616_RS30865 0292d2e5f4694bbb617fb7dd91924355 281 Gene3D G3DSA:3.80.10.10 120 207 7.1E-14 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A616_RS30865 0292d2e5f4694bbb617fb7dd91924355 281 SUPERFAMILY SSF52058 56 261 7.25E-21 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A616_RS30865 0292d2e5f4694bbb617fb7dd91924355 281 Gene3D G3DSA:3.80.10.10 18 119 3.8E-5 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A616_RS22000 ad54f2472441e0956fb682f9cdf415ab 344 Gene3D G3DSA:2.130.10.150 166 339 4.1E-14 T 29-03-2018 A616_RS22000 ad54f2472441e0956fb682f9cdf415ab 344 SUPERFAMILY SSF82171 157 313 1.96E-11 T 29-03-2018 A616_RS31130 bdc479615c9a6207d31e079db56a3006 309 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 300 1.4E-91 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS31130 bdc479615c9a6207d31e079db56a3006 309 SUPERFAMILY SSF53590 2 307 4.06E-93 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS31130 bdc479615c9a6207d31e079db56a3006 309 Gene3D G3DSA:3.90.245.10 1 309 1.1E-104 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 TIGRFAM TIGR00417 speE: spermidine synthase 4 270 4.2E-113 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 Gene3D G3DSA:2.30.140.10 4 51 1.3E-19 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 SUPERFAMILY SSF53335 3 274 2.01E-87 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 Pfam PF01564 Spermine/spermidine synthase domain 58 237 2.4E-62 T 29-03-2018 A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 276 40.638 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 Gene3D G3DSA:3.40.50.150 55 277 8.2E-44 T 29-03-2018 A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A616_RS30220 d8cded2180e54596410ff9072ccd42dc 277 Pfam PF17284 Spermidine synthase tetramerisation domain 3 54 3.0E-19 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 PRINTS PR01543 Arylamine N-acetyltransferase signature 19 42 2.6E-10 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 PRINTS PR01543 Arylamine N-acetyltransferase signature 67 89 2.6E-10 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 PRINTS PR01543 Arylamine N-acetyltransferase signature 43 66 2.6E-10 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 PRINTS PR01543 Arylamine N-acetyltransferase signature 99 124 2.6E-10 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 Gene3D G3DSA:3.30.2140.10 158 252 3.5E-12 T 29-03-2018 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 Pfam PF00797 N-acetyltransferase 19 252 3.1E-58 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 SUPERFAMILY SSF54001 1 251 5.3E-69 T 29-03-2018 A616_RS23515 d80471abe4e60b1aa8912483bd183dca 252 Gene3D G3DSA:3.30.2140.10 1 155 2.9E-37 T 29-03-2018 A616_RS13635 74684cb72f63fb730a1d6768f4096e69 223 TIGRFAM TIGR00017 cmk: cytidylate kinase 1 213 1.2E-82 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A616_RS13635 74684cb72f63fb730a1d6768f4096e69 223 Pfam PF02224 Cytidylate kinase 3 216 1.0E-79 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A616_RS13635 74684cb72f63fb730a1d6768f4096e69 223 Hamap MF_00238 Cytidylate kinase [cmk]. 1 219 33.415 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A616_RS13635 74684cb72f63fb730a1d6768f4096e69 223 SUPERFAMILY SSF52540 1 217 1.92E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13635 74684cb72f63fb730a1d6768f4096e69 223 Gene3D G3DSA:3.40.50.300 1 219 3.2E-53 T 29-03-2018 A616_RS01085 59d3ef7349d183f2ccedc39e8a4d205d 305 SUPERFAMILY SSF54001 180 301 2.31E-34 T 29-03-2018 A616_RS01085 59d3ef7349d183f2ccedc39e8a4d205d 305 Gene3D G3DSA:2.30.30.40 40 111 2.2E-9 T 29-03-2018 A616_RS01085 59d3ef7349d183f2ccedc39e8a4d205d 305 Gene3D G3DSA:3.90.1720.10 140 228 6.5E-13 T 29-03-2018 A616_RS01085 59d3ef7349d183f2ccedc39e8a4d205d 305 Pfam PF00877 NlpC/P60 family 198 296 1.4E-23 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS01085 59d3ef7349d183f2ccedc39e8a4d205d 305 Gene3D G3DSA:2.30.260.10 229 302 2.2E-18 T 29-03-2018 A616_RS28745 0ebfb38edb70746a9e23e03ae404be05 207 Pfam PF10067 Predicted membrane protein (DUF2306) 48 204 6.1E-29 T 29-03-2018 IPR018750 Protein of unknown function DUF2306, membrane A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 SUPERFAMILY SSF53300 406 576 2.64E-32 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 SUPERFAMILY SSF52317 584 677 3.05E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 SUPERFAMILY SSF52317 273 401 3.05E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 Pfam PF07090 Putative glutamine amidotransferase 604 677 5.8E-7 T 29-03-2018 IPR010768 Putative glutamine amidotransferase A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 SMART SM00327 65 219 0.004 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 SMART SM00327 405 582 6.2E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 Gene3D G3DSA:3.40.50.410 62 274 1.2E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 Gene3D G3DSA:3.40.50.880 275 681 4.0E-38 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 Pfam PF00092 von Willebrand factor type A domain 410 575 7.0E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 Pfam PF00092 von Willebrand factor type A domain 68 194 4.9E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27630 969669edcb60f2e537857e911b66ee6b 947 SUPERFAMILY SSF53300 67 189 2.5E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS29420 b109ff54d2d51196bb2f91d5c825a7b6 224 SUPERFAMILY SSF161098 12 207 2.88E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS29420 b109ff54d2d51196bb2f91d5c825a7b6 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 115 1.7E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS29420 b109ff54d2d51196bb2f91d5c825a7b6 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 216 6.5E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS29420 b109ff54d2d51196bb2f91d5c825a7b6 224 Gene3D G3DSA:1.10.3720.10 2 224 7.5E-46 T 29-03-2018 A616_RS11105 61998a657ce20e14abe2e0caa25f3386 251 SUPERFAMILY SSF51182 32 171 3.91E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS11105 61998a657ce20e14abe2e0caa25f3386 251 SMART SM00835 23 159 3.0E-16 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 A616_RS11105 61998a657ce20e14abe2e0caa25f3386 251 Gene3D G3DSA:2.60.120.10 9 169 6.6E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS11105 61998a657ce20e14abe2e0caa25f3386 251 Pfam PF00190 Cupin 37 133 2.8E-10 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 429 751 2.8E-150 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 SUPERFAMILY SSF51726 3 385 7.46E-94 T 29-03-2018 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 6 755 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 PIRSF PIRSF000382 1 760 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 1 756 34.129 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 Gene3D G3DSA:3.20.20.210 1 385 2.5E-122 T 29-03-2018 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 3 311 3.5E-118 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 Gene3D G3DSA:3.20.20.210 388 757 9.0E-121 T 29-03-2018 A616_RS18180 6585723fabe155f4b2e1a7a072bfe751 760 SUPERFAMILY SSF51726 394 755 2.49E-109 T 29-03-2018 A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 176 573 8.4E-123 T 29-03-2018 IPR011340 Cysteine desulfurase-related A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 Pfam PF00266 Aminotransferase class-V 198 571 1.9E-62 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 Gene3D G3DSA:3.90.1150.10 443 581 3.7E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 SUPERFAMILY SSF55729 3 149 5.68E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 Gene3D G3DSA:3.40.640.10 206 442 1.4E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 Pfam PF13302 Acetyltransferase (GNAT) domain 12 147 1.5E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 SUPERFAMILY SSF53383 177 580 4.03E-84 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS14920 108a25619ac27ff5e9c4fd7d5417a59f 581 Gene3D G3DSA:3.40.630.30 1 176 6.9E-22 T 29-03-2018 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 Gene3D G3DSA:3.10.20.70 3 103 1.1E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 SUPERFAMILY SSF55931 102 471 1.18E-131 T 29-03-2018 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 SUPERFAMILY SSF54368 3 98 1.11E-31 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 3.7E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 Gene3D G3DSA:3.30.590.10 104 461 1.6E-123 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 SMART SM01230 101 378 4.5E-149 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 471 1.4E-190 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS27110 c9ead33c60cad777e4bdbb94f4e87cda 472 Pfam PF00120 Glutamine synthetase, catalytic domain 102 469 9.6E-132 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A616_RS30735 3deed45baa6046963cf2c1224f38561f 113 PIRSF PIRSF012296 1 113 9.6E-51 T 29-03-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 A616_RS30735 3deed45baa6046963cf2c1224f38561f 113 SMART SM00877 41 113 4.8E-17 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30735 3deed45baa6046963cf2c1224f38561f 113 SUPERFAMILY SSF143414 41 103 1.83E-16 T 29-03-2018 A616_RS30735 3deed45baa6046963cf2c1224f38561f 113 Pfam PF00936 BMC domain 42 100 4.9E-15 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS24855 86f085e7bed7e5d2fa678bb1719a7254 485 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 156 184 2.8E-5 T 29-03-2018 IPR011096 FTP domain A616_RS24855 86f085e7bed7e5d2fa678bb1719a7254 485 Gene3D G3DSA:3.10.450.40 33 111 0.02 T 29-03-2018 A616_RS28415 867a73f94978c0125cdc87c69c5401ed 362 Pfam PF05076 Suppressor of fused protein (SUFU) 208 350 7.8E-19 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 A616_RS30610 5dbc831739274bdec71051b4accb9520 545 Gene3D G3DSA:3.40.630.10 3 537 9.7E-29 T 29-03-2018 A616_RS30610 5dbc831739274bdec71051b4accb9520 545 Pfam PF01546 Peptidase family M20/M25/M40 80 468 2.6E-10 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS30610 5dbc831739274bdec71051b4accb9520 545 PIRSF PIRSF010386 1 544 8.3E-212 T 29-03-2018 IPR012166 Uncharacterised protein family RocB A616_RS30610 5dbc831739274bdec71051b4accb9520 545 SUPERFAMILY SSF53187 131 234 3.71E-29 T 29-03-2018 A616_RS30610 5dbc831739274bdec71051b4accb9520 545 SUPERFAMILY SSF53187 5 95 3.71E-29 T 29-03-2018 A616_RS30610 5dbc831739274bdec71051b4accb9520 545 SUPERFAMILY SSF53187 422 525 3.71E-29 T 29-03-2018 A616_RS27850 11f90ccc7c87cafb6267e8d430dd7a09 357 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 42 333 5.5E-37 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A616_RS27850 11f90ccc7c87cafb6267e8d430dd7a09 357 SUPERFAMILY SSF51695 38 339 1.05E-61 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS27850 11f90ccc7c87cafb6267e8d430dd7a09 357 Gene3D G3DSA:3.20.20.190 21 347 1.4E-67 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS13215 46de3be4aca7d293cad1399cc7a889af 269 SUPERFAMILY SSF53335 11 258 1.52E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS13215 46de3be4aca7d293cad1399cc7a889af 269 Gene3D G3DSA:3.40.50.150 30 267 3.0E-39 T 29-03-2018 A616_RS13215 46de3be4aca7d293cad1399cc7a889af 269 Pfam PF08241 Methyltransferase domain 49 145 1.1E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS15765 a2e653b3ad35dc9782b939939b8e60e6 224 SUPERFAMILY SSF54001 95 223 1.6E-34 T 29-03-2018 A616_RS15765 a2e653b3ad35dc9782b939939b8e60e6 224 Gene3D G3DSA:3.90.1720.10 91 147 2.0E-16 T 29-03-2018 A616_RS15765 a2e653b3ad35dc9782b939939b8e60e6 224 Gene3D G3DSA:2.30.260.10 148 223 1.1E-18 T 29-03-2018 A616_RS15765 a2e653b3ad35dc9782b939939b8e60e6 224 Pfam PF00877 NlpC/P60 family 113 220 1.1E-27 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS00230 509ddca5707cb9633101d62d68d02622 426 SUPERFAMILY SSF55681 117 420 3.4E-104 T 29-03-2018 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 43.11 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 3.9E-176 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 PIRSF PIRSF001529 1 426 3.5E-187 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 Gene3D G3DSA:3.30.930.10 106 426 1.2E-97 T 29-03-2018 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 Gene3D G3DSA:1.10.287.40 2 105 1.4E-24 T 29-03-2018 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 SUPERFAMILY SSF46589 1 113 2.46E-30 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 4.8E-36 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 5.1E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 5.1E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 5.1E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 5.1E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 5.1E-33 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A616_RS00230 509ddca5707cb9633101d62d68d02622 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 5.1E-31 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A616_RS27115 878871940e1de7ea254eeb298695bd30 235 SUPERFAMILY SSF141523 45 156 1.11E-33 T 29-03-2018 A616_RS27115 878871940e1de7ea254eeb298695bd30 235 Gene3D G3DSA:2.40.440.10 41 157 3.3E-30 T 29-03-2018 A616_RS27115 878871940e1de7ea254eeb298695bd30 235 Gene3D G3DSA:1.10.101.10 162 234 2.8E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS27115 878871940e1de7ea254eeb298695bd30 235 Pfam PF01471 Putative peptidoglycan binding domain 176 228 2.2E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS27115 878871940e1de7ea254eeb298695bd30 235 Pfam PF03734 L,D-transpeptidase catalytic domain 49 155 8.2E-18 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A616_RS27115 878871940e1de7ea254eeb298695bd30 235 SUPERFAMILY SSF47090 164 232 1.13E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS06530 a22be62f82f54f179e293d1ea55ff300 72 Pfam PF02586 SOS response associated peptidase (SRAP) 6 54 1.1E-8 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) A616_RS06530 a22be62f82f54f179e293d1ea55ff300 72 SUPERFAMILY SSF143081 3 66 4.19E-13 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) A616_RS06530 a22be62f82f54f179e293d1ea55ff300 72 Gene3D G3DSA:3.90.1680.10 1 71 1.1E-15 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) A616_RS26860 b2ee048b7434b30e86cb840b4f172a1a 336 Gene3D G3DSA:3.40.33.10 205 333 1.7E-18 T 29-03-2018 IPR014044 CAP domain A616_RS26860 b2ee048b7434b30e86cb840b4f172a1a 336 Pfam PF14504 CAP-associated N-terminal 50 175 4.5E-27 T 29-03-2018 IPR029410 CAP-associated domain A616_RS26860 b2ee048b7434b30e86cb840b4f172a1a 336 Pfam PF00188 Cysteine-rich secretory protein family 218 333 6.9E-21 T 29-03-2018 IPR014044 CAP domain A616_RS26860 b2ee048b7434b30e86cb840b4f172a1a 336 Gene3D G3DSA:3.30.1450.10 39 107 7.0E-9 T 29-03-2018 A616_RS26860 b2ee048b7434b30e86cb840b4f172a1a 336 SUPERFAMILY SSF55797 213 333 3.79E-24 T 29-03-2018 IPR014044 CAP domain A616_RS21810 968949e51627cebd11870c5b974ca88b 345 SUPERFAMILY SSF81345 3 337 8.11E-82 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS21810 968949e51627cebd11870c5b974ca88b 345 Pfam PF01032 FecCD transport family 16 337 5.4E-98 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS21810 968949e51627cebd11870c5b974ca88b 345 Gene3D G3DSA:1.10.3470.10 1 345 3.8E-80 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 SMART SM00842 7 194 6.3E-92 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Gene3D G3DSA:3.90.640.10 246 298 1.0E-17 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Pfam PF14450 Cell division protein FtsA 205 367 1.2E-21 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Pfam PF14450 Cell division protein FtsA 9 185 2.8E-9 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 PIRSF PIRSF003101 2 417 2.2E-141 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 SUPERFAMILY SSF53067 197 369 1.3E-37 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Gene3D G3DSA:3.30.420.40 195 245 3.0E-5 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 2.8E-29 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Gene3D G3DSA:3.30.420.40 1 184 2.6E-33 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 6 371 1.6E-121 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 SUPERFAMILY SSF53067 5 194 2.88E-59 T 29-03-2018 A616_RS21260 52a27f9e558fd2dc7105b3b9a0081d2a 417 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 417 30.04 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A616_RS04055 54865f0a733c83c48947db31bb73e8da 242 SMART SM00382 26 211 6.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04055 54865f0a733c83c48947db31bb73e8da 242 Gene3D G3DSA:3.40.50.300 1 238 1.4E-64 T 29-03-2018 A616_RS04055 54865f0a733c83c48947db31bb73e8da 242 SUPERFAMILY SSF52540 2 225 5.12E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS04055 54865f0a733c83c48947db31bb73e8da 242 Pfam PF00005 ABC transporter 18 161 5.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28890 e6ce915f4e9bd352f68568d82bc30903 403 Gene3D G3DSA:3.40.50.980 54 233 8.8E-12 T 29-03-2018 A616_RS28890 e6ce915f4e9bd352f68568d82bc30903 403 Pfam PF00501 AMP-binding enzyme 63 231 1.3E-8 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS28890 e6ce915f4e9bd352f68568d82bc30903 403 SUPERFAMILY SSF56801 56 281 1.44E-15 T 29-03-2018 A616_RS04900 0a1f232c74fe51b61145a101978c5067 213 Pfam PF03473 MOSC domain 50 160 8.4E-19 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A616_RS04900 0a1f232c74fe51b61145a101978c5067 213 SUPERFAMILY SSF50800 4 212 3.98E-59 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain A616_RS04900 0a1f232c74fe51b61145a101978c5067 213 Pfam PF03475 3-alpha domain 170 213 1.1E-11 T 29-03-2018 IPR005163 3-alpha domain A616_RS04900 0a1f232c74fe51b61145a101978c5067 213 Gene3D G3DSA:2.40.33.20 12 213 1.1E-39 T 29-03-2018 A616_RS30370 931d0081843fcc1b15b24fa217fc48f0 171 Gene3D G3DSA:3.30.457.10 73 154 3.6E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS30370 931d0081843fcc1b15b24fa217fc48f0 171 Gene3D G3DSA:3.30.457.10 33 72 1.3E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS30370 931d0081843fcc1b15b24fa217fc48f0 171 Pfam PF07833 Copper amine oxidase N-terminal domain 42 90 3.1E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 1.9E-107 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 6.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 7.3E-74 T 29-03-2018 A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 Gene3D G3DSA:3.40.50.720 1 38 8.9E-10 T 29-03-2018 A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 Gene3D G3DSA:3.40.50.720 39 246 1.7E-69 T 29-03-2018 A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 1.8E-5 T 29-03-2018 A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.8E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.8E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.8E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS20285 3f6a452fdd30af05f06411a0acfba5b2 246 SUPERFAMILY SSF51735 4 246 2.67E-92 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04655 b23916672938c60ce9812e3d9de4cc74 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 3.7E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS04655 b23916672938c60ce9812e3d9de4cc74 331 Gene3D G3DSA:3.40.50.720 1 133 8.7E-36 T 29-03-2018 A616_RS04655 b23916672938c60ce9812e3d9de4cc74 331 SUPERFAMILY SSF55347 125 294 1.11E-31 T 29-03-2018 A616_RS04655 b23916672938c60ce9812e3d9de4cc74 331 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 223 4.6E-6 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS04655 b23916672938c60ce9812e3d9de4cc74 331 SUPERFAMILY SSF51735 2 147 5.38E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04655 b23916672938c60ce9812e3d9de4cc74 331 Gene3D G3DSA:3.30.360.10 134 330 1.0E-45 T 29-03-2018 A616_RS01310 3ce627ea008e2ccd5ef3cb972c21d6f5 82 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 28 80 4.5E-22 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A616_RS01310 3ce627ea008e2ccd5ef3cb972c21d6f5 82 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 28 79 2.8E-22 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01310 3ce627ea008e2ccd5ef3cb972c21d6f5 82 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 28 56 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01310 3ce627ea008e2ccd5ef3cb972c21d6f5 82 Hamap MF_00422 Protein translocase subunit SecE [secE]. 23 78 13.029 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A616_RS01310 3ce627ea008e2ccd5ef3cb972c21d6f5 82 Gene3D G3DSA:1.20.5.1030 25 76 2.0E-22 T 29-03-2018 A616_RS04495 34ce28d46977dfacbb289397dee9fbf9 127 Pfam PF01047 MarR family 31 88 5.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04495 34ce28d46977dfacbb289397dee9fbf9 127 SMART SM00347 24 121 5.3E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04495 34ce28d46977dfacbb289397dee9fbf9 127 Gene3D G3DSA:1.10.10.10 2 122 2.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04495 34ce28d46977dfacbb289397dee9fbf9 127 SUPERFAMILY SSF46785 5 95 6.31E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14120 23af578a6b0b8d4c4646f0b61f159215 229 Gene3D G3DSA:2.40.260.10 23 229 4.4E-23 T 29-03-2018 IPR023365 Sortase domain A616_RS14120 23af578a6b0b8d4c4646f0b61f159215 229 SUPERFAMILY SSF63817 71 215 6.47E-16 T 29-03-2018 IPR023365 Sortase domain A616_RS14120 23af578a6b0b8d4c4646f0b61f159215 229 Pfam PF04203 Sortase family 76 215 8.0E-20 T 29-03-2018 IPR005754 Sortase family A616_RS04060 0e809e84a9b77ad0f85762e2a8ebf8e8 393 Pfam PF12679 ABC-2 family transporter protein 7 388 7.3E-27 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS04060 0e809e84a9b77ad0f85762e2a8ebf8e8 393 Gene3D G3DSA:3.40.1710.10 50 193 4.8E-15 T 29-03-2018 A616_RS13775 66cf1320909644bf6a53bf0472264b17 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site A616_RS13775 66cf1320909644bf6a53bf0472264b17 321 Pfam PF00348 Polyprenyl synthetase 31 261 2.1E-67 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 A616_RS13775 66cf1320909644bf6a53bf0472264b17 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site A616_RS13775 66cf1320909644bf6a53bf0472264b17 321 SUPERFAMILY SSF48576 4 320 1.44E-81 T 29-03-2018 IPR008949 Isoprenoid synthase domain A616_RS13775 66cf1320909644bf6a53bf0472264b17 321 Gene3D G3DSA:1.10.600.10 2 321 3.2E-89 T 29-03-2018 IPR008949 Isoprenoid synthase domain A616_RS05480 e18891aabe45e3fbaed145f12437eb43 318 Pfam PF08279 HTH domain 5 57 8.5E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS05480 e18891aabe45e3fbaed145f12437eb43 318 SUPERFAMILY SSF46785 2 62 5.33E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05480 e18891aabe45e3fbaed145f12437eb43 318 PIRSF PIRSF016838 1 56 0.063 T 29-03-2018 IPR028349 Protein PafC A616_RS05480 e18891aabe45e3fbaed145f12437eb43 318 PIRSF PIRSF016838 91 318 1.4E-13 T 29-03-2018 IPR028349 Protein PafC A616_RS05480 e18891aabe45e3fbaed145f12437eb43 318 Pfam PF13280 WYL domain 140 312 8.0E-34 T 29-03-2018 IPR026881 WYL domain A616_RS05480 e18891aabe45e3fbaed145f12437eb43 318 Gene3D G3DSA:1.10.10.10 2 64 3.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01700 b9e1154544398384e1e4972049e7d69f 207 Pfam PF04519 Polymer-forming cytoskeletal 133 182 4.5E-7 T 29-03-2018 IPR007607 Protein of unknown function DUF583 A616_RS01700 b9e1154544398384e1e4972049e7d69f 207 Pfam PF13490 Putative zinc-finger 3 37 1.2E-7 T 29-03-2018 IPR027383 Putative zinc-finger A616_RS25155 cdd27e6d875b841de42bf68450499926 586 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 303 316 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 SUPERFAMILY SSF46689 493 586 4.87E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Gene3D G3DSA:3.30.450.20 137 265 4.3E-17 T 29-03-2018 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Gene3D G3DSA:1.10.10.60 524 586 8.2E-16 T 29-03-2018 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Pfam PF00158 Sigma-54 interaction domain 281 446 1.2E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Pfam PF02954 Bacterial regulatory protein, Fis family 548 586 8.2E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 SMART SM00091 140 205 3.8E-5 T 29-03-2018 IPR000014 PAS domain A616_RS25155 cdd27e6d875b841de42bf68450499926 586 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 493 502 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS25155 cdd27e6d875b841de42bf68450499926 586 SMART SM00382 299 443 1.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Gene3D G3DSA:3.40.50.300 276 452 3.6E-25 T 29-03-2018 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 570 586 2.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 553 570 2.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Pfam PF00989 PAS fold 142 229 3.1E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 A616_RS25155 cdd27e6d875b841de42bf68450499926 586 SUPERFAMILY SSF55785 138 243 4.19E-11 T 29-03-2018 IPR000014 PAS domain A616_RS25155 cdd27e6d875b841de42bf68450499926 586 SUPERFAMILY SSF52540 279 523 1.89E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25155 cdd27e6d875b841de42bf68450499926 586 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 252 2.1E-8 T 29-03-2018 IPR000014 PAS domain A616_RS25155 cdd27e6d875b841de42bf68450499926 586 Gene3D G3DSA:1.10.8.60 453 523 3.1E-23 T 29-03-2018 A616_RS18960 63653684bdfea418653dfe7b0c4da8ad 371 Pfam PF13039 Protein of unknown function (DUF3900) 2 252 1.6E-119 T 29-03-2018 IPR025006 Protein of unknown function DUF3900 A616_RS18960 63653684bdfea418653dfe7b0c4da8ad 371 Pfam PF13037 Domain of unknown function (DUF3898) 259 347 2.0E-40 T 29-03-2018 IPR025012 Domain of unknown function DUF3898 A616_RS15115 47af8213bad387e360d3291bd8159c3f 140 SUPERFAMILY SSF54593 1 131 2.15E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15115 47af8213bad387e360d3291bd8159c3f 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 2.4E-17 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS15115 47af8213bad387e360d3291bd8159c3f 140 Gene3D G3DSA:3.10.180.10 1 133 2.9E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 125 139 4.9E-22 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 243 253 4.9E-22 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 53 62 4.9E-22 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 113 125 4.9E-22 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 175 187 4.9E-22 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 153 165 4.9E-22 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 230 242 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 182 197 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 57 253 2.5E-86 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 Pfam PF00813 FliP family 57 249 1.5E-80 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 203 224 3.9E-66 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 74 94 3.9E-66 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 182 202 3.9E-66 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 94 113 3.9E-66 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 227 252 3.9E-66 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS19965 7bbe4d22865db5e1cc40d99d306a2408 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 55 74 3.9E-66 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A616_RS04425 a8c7471980dce1f9b97c89218a2d3bce 578 Gene3D G3DSA:2.60.40.1630 144 302 1.0E-25 T 29-03-2018 A616_RS04425 a8c7471980dce1f9b97c89218a2d3bce 578 Pfam PF13786 Domain of unknown function (DUF4179) 96 199 1.6E-18 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS04425 a8c7471980dce1f9b97c89218a2d3bce 578 Gene3D G3DSA:2.60.40.1640 307 451 3.5E-12 T 29-03-2018 A616_RS04425 a8c7471980dce1f9b97c89218a2d3bce 578 Gene3D G3DSA:2.60.40.1640 452 578 7.3E-5 T 29-03-2018 A616_RS12665 2e857791783ce41102ab4f3c349f6a51 389 Gene3D G3DSA:3.90.1150.10 276 389 2.5E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12665 2e857791783ce41102ab4f3c349f6a51 389 Gene3D G3DSA:3.40.640.10 101 275 2.3E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS12665 2e857791783ce41102ab4f3c349f6a51 389 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 387 7.3E-146 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 A616_RS12665 2e857791783ce41102ab4f3c349f6a51 389 Pfam PF00155 Aminotransferase class I and II 44 383 2.1E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS12665 2e857791783ce41102ab4f3c349f6a51 389 Gene3D G3DSA:3.90.1150.10 1 100 7.4E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS12665 2e857791783ce41102ab4f3c349f6a51 389 SUPERFAMILY SSF53383 13 387 2.39E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS14595 8b6964cf757b8fb6a6d7d6a1a859e80d 314 SUPERFAMILY SSF56266 1 312 3.14E-71 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS14595 8b6964cf757b8fb6a6d7d6a1a859e80d 314 Gene3D G3DSA:3.60.70.12 1 314 1.8E-103 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS14595 8b6964cf757b8fb6a6d7d6a1a859e80d 314 Pfam PF03576 Peptidase family S58 1 306 2.5E-60 T 29-03-2018 IPR005321 Peptidase S58, DmpA A616_RS18945 79b0207375f3d2f81f326bd7fd021bf1 314 Gene3D G3DSA:1.50.10.20 3 276 7.5E-9 T 29-03-2018 A616_RS18945 79b0207375f3d2f81f326bd7fd021bf1 314 SUPERFAMILY SSF48208 44 291 1.7E-9 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A616_RS28910 90918bb50f02de14f30dfdf02b51e301 82 Gene3D G3DSA:1.10.1200.10 3 81 6.2E-14 T 29-03-2018 A616_RS28910 90918bb50f02de14f30dfdf02b51e301 82 SUPERFAMILY SSF47336 7 78 1.22E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28910 90918bb50f02de14f30dfdf02b51e301 82 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site A616_RS28910 90918bb50f02de14f30dfdf02b51e301 82 Pfam PF00550 Phosphopantetheine attachment site 9 72 9.6E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS11625 f78fb5f642096758b11e2757766c4190 394 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 7 386 1.8E-105 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD A616_RS11625 f78fb5f642096758b11e2757766c4190 394 Pfam PF06898 Putative stage IV sporulation protein YqfD 8 385 7.4E-118 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD A616_RS11625 f78fb5f642096758b11e2757766c4190 394 PIRSF PIRSF029895 1 394 6.2E-115 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 347 454 2.5E-30 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:3.10.600.10 466 534 4.1E-17 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SUPERFAMILY SSF56059 88 327 1.03E-65 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Pfam PF00364 Biotin-requiring enzyme 1083 1147 2.0E-16 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Pfam PF02436 Conserved carboxylase domain 831 1031 4.0E-77 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:3.40.50.20 5 128 1.5E-50 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 PIRSF PIRSF001594 1 1148 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:3.30.470.20 215 456 2.2E-92 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SUPERFAMILY SSF51230 1069 1148 7.72E-21 T 29-03-2018 IPR011053 Single hybrid motif A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SMART SM00878 347 454 3.0E-52 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 327 1.8E-79 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SUPERFAMILY SSF52440 4 117 3.74E-44 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SUPERFAMILY SSF51246 342 460 9.42E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:1.10.10.60 947 992 4.0E-19 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:3.30.1490.20 129 214 2.9E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SUPERFAMILY SSF89000 836 1013 1.92E-58 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:3.20.20.70 535 834 2.6E-76 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Pfam PF00682 HMGL-like 537 808 2.8E-31 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:2.40.50.100 1077 1148 2.4E-18 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 9 1148 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 115 4.9E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 SUPERFAMILY SSF51569 528 839 2.38E-87 T 29-03-2018 A616_RS22570 b745900ac4d81e5e3952698fd1e5e1f7 1148 Gene3D G3DSA:3.10.600.10 993 1064 4.1E-21 T 29-03-2018 A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 305 5.9E-69 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 SUPERFAMILY SSF51735 1 171 2.53E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 SUPERFAMILY SSF48179 178 303 3.09E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 301 2.5E-28 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 Gene3D G3DSA:1.10.1040.10 178 309 3.8E-32 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 152 1.1E-35 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A616_RS27105 4e15bbb6cc5ca5590fcb5f0f9422f2f7 309 Gene3D G3DSA:3.40.50.720 1 177 6.1E-29 T 29-03-2018 A616_RS07210 dfd86aa4832eaf1b766b9b00b668797d 305 Pfam PF00072 Response regulator receiver domain 5 114 4.4E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07210 dfd86aa4832eaf1b766b9b00b668797d 305 SUPERFAMILY SSF52172 1 135 1.99E-21 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS07210 dfd86aa4832eaf1b766b9b00b668797d 305 Gene3D G3DSA:3.40.50.2300 1 286 2.2E-20 T 29-03-2018 A616_RS07210 dfd86aa4832eaf1b766b9b00b668797d 305 SMART SM00448 2 114 9.1E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS07210 dfd86aa4832eaf1b766b9b00b668797d 305 Pfam PF08664 YcbB domain 163 298 5.4E-46 T 29-03-2018 IPR013972 YcbB domain A616_RS27535 c16015acaaf01cc5bf16f0f5bd4e4a67 99 Gene3D G3DSA:3.30.70.100 1 98 2.1E-22 T 29-03-2018 A616_RS27535 c16015acaaf01cc5bf16f0f5bd4e4a67 99 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 99 6.9E-30 T 29-03-2018 IPR009799 EthD domain A616_RS27535 c16015acaaf01cc5bf16f0f5bd4e4a67 99 SUPERFAMILY SSF54909 1 99 1.95E-25 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS27535 c16015acaaf01cc5bf16f0f5bd4e4a67 99 Pfam PF07110 EthD domain 15 88 3.9E-10 T 29-03-2018 IPR009799 EthD domain A616_RS08925 8a3a54cef699c8101b7be82d560dfc2a 185 SUPERFAMILY SSF55729 13 169 6.9E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS08925 8a3a54cef699c8101b7be82d560dfc2a 185 Pfam PF13302 Acetyltransferase (GNAT) domain 21 161 1.3E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS08925 8a3a54cef699c8101b7be82d560dfc2a 185 Gene3D G3DSA:3.40.630.30 4 179 1.1E-30 T 29-03-2018 A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 SMART SM00418 264 342 1.1E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 Pfam PF01022 Bacterial regulatory protein, arsR family 271 315 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 298 313 1.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 266 281 1.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 313 328 1.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 SUPERFAMILY SSF46785 258 335 1.28E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02580 f1a99abadd372ad2caeda88bac8a65e7 365 Gene3D G3DSA:1.10.10.10 255 346 9.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PIRSF PIRSF000099 4 422 1.5E-181 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 419 44.308 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 Pfam PF00815 Histidinol dehydrogenase 19 419 4.4E-179 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 Gene3D G3DSA:3.40.50.1980 19 217 1.1E-92 T 29-03-2018 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 Gene3D G3DSA:3.40.50.1980 218 363 4.4E-70 T 29-03-2018 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 221 253 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 SUPERFAMILY SSF53720 20 419 1.45E-87 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 192 217 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 243 262 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 26 50 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 162 188 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 221 242 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 312 337 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 127 153 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 PRINTS PR00083 Histidinol dehydrogenase signature 353 371 6.7E-92 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS29225 8d158f2ce2f4b9cfb625dcf854b36844 432 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 26 418 9.5E-175 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A616_RS21335 14a1450c25433eb96f368189eb792a26 314 Gene3D G3DSA:1.10.150.170 115 220 9.7E-41 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS21335 14a1450c25433eb96f368189eb792a26 314 SUPERFAMILY SSF81799 117 218 1.31E-36 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS21335 14a1450c25433eb96f368189eb792a26 314 PIRSF PIRSF004486 2 314 5.0E-110 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS21335 14a1450c25433eb96f368189eb792a26 314 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 6 313 1.3E-122 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS21335 14a1450c25433eb96f368189eb792a26 314 SUPERFAMILY SSF53335 218 314 1.73E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS21335 14a1450c25433eb96f368189eb792a26 314 SUPERFAMILY SSF53335 7 116 1.73E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS21335 14a1450c25433eb96f368189eb792a26 314 Pfam PF01795 MraW methylase family 6 313 4.5E-130 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS21335 14a1450c25433eb96f368189eb792a26 314 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 8 314 39.425 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.9E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.9E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.9E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 PRINTS PR00070 Dihydrofolate reductase signature 91 105 1.9E-14 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 SUPERFAMILY SSF53597 2 159 1.22E-56 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 PIRSF PIRSF000194 1 162 4.6E-56 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 Gene3D G3DSA:3.40.430.10 1 162 3.0E-53 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 A616_RS16490 14af837e934463ded3e7ff4e8f3910f4 162 Pfam PF00186 Dihydrofolate reductase 2 159 5.2E-59 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A616_RS08855 278e8d40bae549a43664cfc867d60039 401 SUPERFAMILY SSF51621 35 256 1.73E-15 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS08855 278e8d40bae549a43664cfc867d60039 401 SUPERFAMILY SSF51621 291 324 1.73E-15 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS08855 278e8d40bae549a43664cfc867d60039 401 Gene3D G3DSA:3.20.20.360 28 351 1.5E-34 T 29-03-2018 A616_RS08855 278e8d40bae549a43664cfc867d60039 401 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 378 2.5E-132 T 29-03-2018 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 10 358 7.1E-112 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 Gene3D G3DSA:3.30.1490.20 148 223 1.3E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 SUPERFAMILY SSF52440 8 146 2.01E-34 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 Gene3D G3DSA:3.40.50.20 1 147 1.1E-45 T 29-03-2018 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 SUPERFAMILY SSF56059 147 363 2.12E-58 T 29-03-2018 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 302 331 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 114 125 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 Gene3D G3DSA:3.30.470.20 224 370 6.0E-43 T 29-03-2018 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 9 361 41.853 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 PIRSF PIRSF039102 6 369 5.3E-118 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 Pfam PF01820 D-ala D-ala ligase N-terminus 11 136 5.1E-30 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS11535 29f9bc15935c9177c49408733cfcae1c 378 Pfam PF07478 D-ala D-ala ligase C-terminus 155 358 3.4E-78 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS24335 e9069b0926d5955dbbef223867a82475 367 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 366 9.9E-72 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS24335 e9069b0926d5955dbbef223867a82475 367 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 198 364 2.1E-26 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS14185 1982886bad0f8ab3e57e71300d7be176 314 Gene3D G3DSA:3.40.250.10 112 223 2.8E-27 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS14185 1982886bad0f8ab3e57e71300d7be176 314 SMART SM00450 117 218 2.7E-21 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS14185 1982886bad0f8ab3e57e71300d7be176 314 SUPERFAMILY SSF52821 90 242 3.01E-34 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS14185 1982886bad0f8ab3e57e71300d7be176 314 Pfam PF12368 Rhodanase C-terminal 224 291 2.5E-16 T 29-03-2018 IPR022111 Rhodanase, C-terminal A616_RS14185 1982886bad0f8ab3e57e71300d7be176 314 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 260 40.771 T 29-03-2018 IPR020936 Uncharacterised protein family UPF0176 A616_RS14185 1982886bad0f8ab3e57e71300d7be176 314 Pfam PF00581 Rhodanese-like domain 119 212 4.6E-13 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS29145 b304facb2032673311288e1a7d3b529e 293 PIRSF PIRSF005052 10 293 1.3E-109 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 A616_RS29145 b304facb2032673311288e1a7d3b529e 293 Gene3D G3DSA:3.40.50.300 10 164 9.6E-9 T 29-03-2018 A616_RS29145 b304facb2032673311288e1a7d3b529e 293 Pfam PF03668 P-loop ATPase protein family 10 292 2.0E-113 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 A616_RS29145 b304facb2032673311288e1a7d3b529e 293 SUPERFAMILY SSF52540 12 167 4.84E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29145 b304facb2032673311288e1a7d3b529e 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 10 291 42.127 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 A616_RS31005 8b3f94385684d640354acd1f0d4815e2 248 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 1 244 39.331 T 29-03-2018 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 A616_RS31005 8b3f94385684d640354acd1f0d4815e2 248 Gene3D G3DSA:3.20.20.370 1 248 9.1E-85 T 29-03-2018 A616_RS31005 8b3f94385684d640354acd1f0d4815e2 248 SUPERFAMILY SSF88713 1 247 6.23E-79 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS31005 8b3f94385684d640354acd1f0d4815e2 248 Pfam PF04794 YdjC-like protein 2 235 3.8E-67 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like A616_RS12900 4ffecb1065518482c92a76dceaace62a 53 Pfam PF14038 YqzE-like protein 2 51 5.4E-22 T 29-03-2018 IPR025622 YqzE-like protein A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 Gene3D G3DSA:3.40.1710.10 48 201 1.4E-25 T 29-03-2018 A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 Pfam PF12698 ABC-2 family transporter protein 26 174 6.6E-8 T 29-03-2018 A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 Pfam PF12698 ABC-2 family transporter protein 683 867 3.2E-11 T 29-03-2018 A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 670 870 7.6E-46 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 Gene3D G3DSA:3.90.20.10 233 388 0.038 T 29-03-2018 A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 Gene3D G3DSA:1.20.1170.10 389 618 0.0036 T 29-03-2018 A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 Gene3D G3DSA:1.20.1170.10 623 726 5.1E-7 T 29-03-2018 A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 172 2.9E-44 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal A616_RS31550 b71d4654528ec13eaefa8160fe9f7c04 891 SUPERFAMILY SSF58104 266 468 2.75E-5 T 29-03-2018 A616_RS08030 53ee96c030994a46b6f10c2ef3e00159 314 Pfam PF04294 VanW like protein 147 275 3.6E-51 T 29-03-2018 IPR007391 Vancomycin resistance VanW A616_RS02275 314518956ff045f9e195fe9e60920060 557 Pfam PF03814 Potassium-transporting ATPase A subunit 8 554 1.7E-245 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A616_RS02275 314518956ff045f9e195fe9e60920060 557 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 2 555 2.5E-218 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A616_RS02275 314518956ff045f9e195fe9e60920060 557 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 556 33.464 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A616_RS02275 314518956ff045f9e195fe9e60920060 557 PIRSF PIRSF001294 1 557 1.1E-245 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.1E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 Gene3D G3DSA:1.10.357.10 72 191 1.2E-11 T 29-03-2018 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 Gene3D G3DSA:1.10.260.40 41 71 1.3E-13 T 29-03-2018 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 Gene3D G3DSA:1.10.10.60 2 40 1.1E-13 T 29-03-2018 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS15185 b1b54a89ecb374cd86679ee53bc1c2c0 199 SUPERFAMILY SSF46689 10 84 1.6E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS05445 b61bb2078c24c1e61bc9f52a784ecb1a 362 Gene3D G3DSA:3.40.190.10 200 339 3.0E-17 T 29-03-2018 A616_RS05445 b61bb2078c24c1e61bc9f52a784ecb1a 362 Pfam PF13343 Bacterial extracellular solute-binding protein 98 343 2.3E-28 T 29-03-2018 A616_RS05445 b61bb2078c24c1e61bc9f52a784ecb1a 362 PIRSF PIRSF002825 2 362 4.6E-82 T 29-03-2018 IPR026045 Ferric binding protein A616_RS05445 b61bb2078c24c1e61bc9f52a784ecb1a 362 Gene3D G3DSA:3.40.190.10 1 194 3.2E-24 T 29-03-2018 A616_RS05445 b61bb2078c24c1e61bc9f52a784ecb1a 362 SUPERFAMILY SSF53850 46 358 3.9E-79 T 29-03-2018 A616_RS00695 94452c1434bdc4372ded419288742901 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A616_RS00695 94452c1434bdc4372ded419288742901 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 36.83 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A616_RS00695 94452c1434bdc4372ded419288742901 189 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.4E-59 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A616_RS00695 94452c1434bdc4372ded419288742901 189 Gene3D G3DSA:3.40.50.1470 1 189 4.2E-75 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A616_RS00695 94452c1434bdc4372ded419288742901 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A616_RS00695 94452c1434bdc4372ded419288742901 189 SUPERFAMILY SSF53178 2 186 8.37E-69 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A616_RS00695 94452c1434bdc4372ded419288742901 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 186 3.9E-68 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A616_RS27775 472f2440835f60362e06b960cc844890 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 352 5.7E-57 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS27775 472f2440835f60362e06b960cc844890 368 Pfam PF03845 Spore germination protein 7 322 2.0E-28 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 SUPERFAMILY SSF46689 477 568 1.66E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 SMART SM00382 287 431 1.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 SUPERFAMILY SSF52540 282 506 7.8E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 Pfam PF01590 GAF domain 80 175 1.4E-5 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 Gene3D G3DSA:3.40.50.300 209 440 4.9E-22 T 29-03-2018 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 Pfam PF02954 Bacterial regulatory protein, Fis family 525 566 7.6E-17 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 Gene3D G3DSA:1.10.8.60 441 508 9.1E-16 T 29-03-2018 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 Pfam PF00158 Sigma-54 interaction domain 274 434 6.4E-63 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 Gene3D G3DSA:1.10.10.60 520 570 2.5E-18 T 29-03-2018 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 291 304 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 532 549 8.6E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS30950 0dba32173b1d86bfc1370c9f85330ce9 577 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 549 569 8.6E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A616_RS25955 a8296a6a63581edea26a480c08847a5e 257 SUPERFAMILY SSF55729 79 246 1.72E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25955 a8296a6a63581edea26a480c08847a5e 257 Gene3D G3DSA:3.40.630.30 105 252 3.5E-16 T 29-03-2018 A616_RS25955 a8296a6a63581edea26a480c08847a5e 257 Pfam PF13527 Acetyltransferase (GNAT) domain 121 245 1.6E-6 T 29-03-2018 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 Gene3D G3DSA:2.30.38.10 340 423 8.8E-28 T 29-03-2018 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 Pfam PF00501 AMP-binding enzyme 29 430 9.7E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 Gene3D G3DSA:3.40.50.980 187 339 9.9E-42 T 29-03-2018 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 Gene3D G3DSA:3.30.300.30 425 530 1.1E-29 T 29-03-2018 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 SUPERFAMILY SSF56801 18 526 4.32E-152 T 29-03-2018 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 Gene3D G3DSA:3.40.50.980 20 186 4.4E-42 T 29-03-2018 A616_RS15355 c8959a6bb8fbfac15c3801d3df71b313 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 514 4.5E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS13850 fbfa1e9582c7dd70641caca9442f63c7 373 Gene3D G3DSA:2.30.40.10 5 65 1.6E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13850 fbfa1e9582c7dd70641caca9442f63c7 373 Gene3D G3DSA:2.30.40.10 238 351 1.1E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13850 fbfa1e9582c7dd70641caca9442f63c7 373 SUPERFAMILY SSF51338 6 60 3.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13850 fbfa1e9582c7dd70641caca9442f63c7 373 SUPERFAMILY SSF51338 301 363 3.09E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS13850 fbfa1e9582c7dd70641caca9442f63c7 373 Gene3D G3DSA:3.20.20.140 66 162 8.9E-5 T 29-03-2018 A616_RS13850 fbfa1e9582c7dd70641caca9442f63c7 373 Pfam PF01979 Amidohydrolase family 282 346 5.8E-7 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS05450 8bc77e5a5ae9ca501db06d007ef45983 551 Gene3D G3DSA:1.10.3720.10 52 273 8.1E-23 T 29-03-2018 A616_RS05450 8bc77e5a5ae9ca501db06d007ef45983 551 Gene3D G3DSA:1.10.3720.10 291 551 9.4E-30 T 29-03-2018 A616_RS05450 8bc77e5a5ae9ca501db06d007ef45983 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 351 548 9.0E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS05450 8bc77e5a5ae9ca501db06d007ef45983 551 SUPERFAMILY SSF161098 292 545 3.92E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS05450 8bc77e5a5ae9ca501db06d007ef45983 551 SUPERFAMILY SSF161098 16 267 6.65E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS18105 afaa1308e4c508afa2c6baf52f3e7924 419 Pfam PF07690 Major Facilitator Superfamily 10 363 9.5E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS18105 afaa1308e4c508afa2c6baf52f3e7924 419 Gene3D G3DSA:1.20.1250.20 1 193 4.3E-31 T 29-03-2018 A616_RS18105 afaa1308e4c508afa2c6baf52f3e7924 419 SUPERFAMILY SSF103473 3 409 3.01E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS18105 afaa1308e4c508afa2c6baf52f3e7924 419 Gene3D G3DSA:1.20.1250.20 194 412 1.6E-22 T 29-03-2018 A616_RS31605 8b6025aec0c67ff193df335d45e6a077 336 SUPERFAMILY SSF81345 7 330 3.27E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS31605 8b6025aec0c67ff193df335d45e6a077 336 Gene3D G3DSA:1.10.3470.10 7 336 3.9E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS31605 8b6025aec0c67ff193df335d45e6a077 336 Pfam PF01032 FecCD transport family 23 330 2.0E-91 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS26420 6a47a692d3acabc94dd5ff0116ffd060 361 SUPERFAMILY SSF56112 6 153 7.14E-6 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS26420 6a47a692d3acabc94dd5ff0116ffd060 361 SUPERFAMILY SSF56112 234 294 5.1E-5 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS26420 6a47a692d3acabc94dd5ff0116ffd060 361 Gene3D G3DSA:3.90.1200.10 98 192 4.9E-4 T 29-03-2018 A616_RS26420 6a47a692d3acabc94dd5ff0116ffd060 361 Gene3D G3DSA:3.90.1200.10 193 324 1.5E-5 T 29-03-2018 A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 SMART SM00491 501 627 9.1E-9 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 Gene3D G3DSA:3.40.50.300 34 461 1.3E-18 T 29-03-2018 A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 Pfam PF13307 Helicase C-terminal domain 485 633 1.4E-24 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 SUPERFAMILY SSF52540 18 129 9.31E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 SUPERFAMILY SSF52540 586 622 9.31E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 SUPERFAMILY SSF52540 211 273 9.31E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14730 7c675770609b8351c213dac2c1a7f053 654 Gene3D G3DSA:3.40.50.300 462 639 2.1E-7 T 29-03-2018 A616_RS28460 f5a55af4314ed89d4711d728d505f92a 220 Gene3D G3DSA:3.40.109.10 3 220 4.7E-39 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS28460 f5a55af4314ed89d4711d728d505f92a 220 Pfam PF00881 Nitroreductase family 12 199 8.3E-26 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS28460 f5a55af4314ed89d4711d728d505f92a 220 SUPERFAMILY SSF55469 6 217 2.88E-53 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS26855 34f3cddd40be810586a827de85d20ae1 163 Pfam PF06271 RDD family 28 154 4.4E-23 T 29-03-2018 IPR010432 RDD A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 SUPERFAMILY SSF51735 162 314 1.85E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 PIRSF PIRSF000445 1 435 3.5E-159 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 420 30.44 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 5.8E-48 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 2.3E-45 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 Gene3D G3DSA:1.10.1200.70 332 420 4.4E-24 T 29-03-2018 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 Gene3D G3DSA:3.40.50.720 161 313 3.2E-27 T 29-03-2018 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 419 8.5E-149 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 SUPERFAMILY SSF69742 1 158 1.06E-48 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 SUPERFAMILY SSF69075 317 420 7.19E-20 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS10330 38517a6f9e67784d4dcb19e772ac5850 454 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 323 419 1.4E-23 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A616_RS20610 62d5fcc533fd5df4998b6229c69ebca0 438 Gene3D G3DSA:1.20.1250.20 36 225 7.5E-18 T 29-03-2018 A616_RS20610 62d5fcc533fd5df4998b6229c69ebca0 438 Gene3D G3DSA:1.20.1250.20 237 438 2.5E-7 T 29-03-2018 A616_RS20610 62d5fcc533fd5df4998b6229c69ebca0 438 Pfam PF13347 MFS/sugar transport protein 160 393 1.3E-8 T 29-03-2018 A616_RS20610 62d5fcc533fd5df4998b6229c69ebca0 438 SUPERFAMILY SSF103473 41 430 3.01E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 SMART SM00346 2 94 1.3E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 Gene3D G3DSA:1.10.10.10 1 90 1.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 Gene3D G3DSA:3.30.450.40 91 247 1.2E-34 T 29-03-2018 IPR029016 GAF domain-like A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 Pfam PF01614 Bacterial transcriptional regulator 122 239 1.7E-18 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 SUPERFAMILY SSF55781 71 242 7.19E-37 T 29-03-2018 IPR029016 GAF domain-like A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 SUPERFAMILY SSF46785 2 78 2.82E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28235 99caf4f85cdeee263a58d471a394e382 247 Pfam PF09339 IclR helix-turn-helix domain 6 56 1.1E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS17415 168b695b2b0ec956994985ff5653fcd5 142 Pfam PF07761 Protein of unknown function (DUF1617) 9 131 1.1E-4 T 29-03-2018 IPR011675 Protein of unknown function DUF1617 A616_RS24175 cd84b7b57877d444cf8d2cad1fdea0de 81 Pfam PF13131 Protein of unknown function (DUF3951) 8 52 3.8E-10 T 29-03-2018 IPR025028 Protein of unknown function DUF3951 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 ProSitePatterns PS00211 ABC transporters family signature. 587 601 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 Pfam PF00005 ABC transporter 466 615 5.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 SUPERFAMILY SSF52540 443 685 7.83E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 Gene3D G3DSA:3.40.50.300 436 691 1.6E-73 T 29-03-2018 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 SMART SM00382 475 667 3.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 Pfam PF00664 ABC transporter transmembrane region 171 405 8.7E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 SUPERFAMILY SSF90123 9 47 1.05E-75 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 SUPERFAMILY SSF90123 161 432 1.05E-75 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS26870 233066290879429147a9fbf0b4f1c6c4 694 Gene3D G3DSA:1.20.1560.10 2 435 1.1E-70 T 29-03-2018 A616_RS27035 9ec6dc60e0706cc8a8c1905f340b7065 204 Gene3D G3DSA:1.20.1070.10 4 204 4.7E-4 T 29-03-2018 A616_RS27035 9ec6dc60e0706cc8a8c1905f340b7065 204 Pfam PF01810 LysE type translocator 15 199 9.2E-32 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS27305 af91d329e999ec5a348eac701d09ccfc 379 Pfam PF12698 ABC-2 family transporter protein 27 371 6.1E-46 T 29-03-2018 A616_RS27305 af91d329e999ec5a348eac701d09ccfc 379 Gene3D G3DSA:3.40.1710.10 42 199 2.0E-24 T 29-03-2018 A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 Gene3D G3DSA:1.20.1260.10 1 154 1.1E-44 T 29-03-2018 IPR012347 Ferritin-related A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 59 75 1.8E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 130 148 1.8E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 35 51 1.8E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 SUPERFAMILY SSF47240 11 151 6.09E-44 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 ProSitePatterns PS00819 Dps protein family signature 2. 61 75 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 Pfam PF00210 Ferritin-like domain 15 151 2.2E-30 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A616_RS24805 9bdf83f845106bf16d4d765939b4d128 154 PIRSF PIRSF005900 1 154 5.8E-49 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS06660 c38af87adaeaa233c658d18164f60b53 212 SUPERFAMILY SSF52374 2 209 5.0E-41 T 29-03-2018 A616_RS06660 c38af87adaeaa233c658d18164f60b53 212 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 207 1.1E-42 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A616_RS06660 c38af87adaeaa233c658d18164f60b53 212 Pfam PF01467 Cytidylyltransferase-like 5 181 3.1E-22 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A616_RS06660 c38af87adaeaa233c658d18164f60b53 212 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 208 24.714 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 A616_RS06660 c38af87adaeaa233c658d18164f60b53 212 Gene3D G3DSA:3.40.50.620 1 208 1.6E-48 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS30250 72c1f9eac87ac85459ea329a61ad2de6 1328 Gene3D G3DSA:2.60.40.10 183 311 2.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS30250 72c1f9eac87ac85459ea329a61ad2de6 1328 Gene3D G3DSA:2.60.40.10 827 908 0.057 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 SUPERFAMILY SSF46785 7 93 2.16E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 8.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 8.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 8.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 Pfam PF12840 Helix-turn-helix domain 9 67 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 SMART SM00418 9 90 4.5E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS15500 8414414d93b115398dfcd74d43f0126e 123 Gene3D G3DSA:1.10.10.10 1 110 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30325 8241068aa3762ed9ebb82b894b478c97 415 Pfam PF07690 Major Facilitator Superfamily 15 243 3.7E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS30325 8241068aa3762ed9ebb82b894b478c97 415 Pfam PF07690 Major Facilitator Superfamily 263 402 2.1E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS30325 8241068aa3762ed9ebb82b894b478c97 415 Gene3D G3DSA:1.20.1250.20 204 405 5.5E-23 T 29-03-2018 A616_RS30325 8241068aa3762ed9ebb82b894b478c97 415 SUPERFAMILY SSF103473 9 405 8.11E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS30325 8241068aa3762ed9ebb82b894b478c97 415 Gene3D G3DSA:1.20.1250.20 9 198 4.7E-34 T 29-03-2018 A616_RS30325 8241068aa3762ed9ebb82b894b478c97 415 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS18570 1348ac7ef4bf9ea6054627d2b1182e7c 188 Gene3D G3DSA:3.40.30.10 2 187 1.6E-11 T 29-03-2018 A616_RS18570 1348ac7ef4bf9ea6054627d2b1182e7c 188 SUPERFAMILY SSF52833 31 127 2.39E-6 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS18570 1348ac7ef4bf9ea6054627d2b1182e7c 188 Pfam PF14595 Thioredoxin 12 141 5.9E-39 T 29-03-2018 A616_RS19045 4fad696de6ea9f0e05cb604493a7281e 341 Gene3D G3DSA:3.90.1150.10 248 341 1.1E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS19045 4fad696de6ea9f0e05cb604493a7281e 341 SUPERFAMILY SSF53383 3 339 4.44E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS19045 4fad696de6ea9f0e05cb604493a7281e 341 Pfam PF01212 Beta-eliminating lyase 4 284 2.3E-97 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A616_RS19045 4fad696de6ea9f0e05cb604493a7281e 341 Gene3D G3DSA:3.40.640.10 1 247 6.6E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS19045 4fad696de6ea9f0e05cb604493a7281e 341 PIRSF PIRSF017617 1 341 2.4E-132 T 29-03-2018 IPR023603 Threonine aldolase A616_RS02855 38d224ad06d2e7f92df1588b1e37d68e 345 Pfam PF14285 Domain of unknown function (DUF4367) 238 338 2.4E-5 T 29-03-2018 IPR025377 Domain of unknown function DUF4367 A616_RS02855 38d224ad06d2e7f92df1588b1e37d68e 345 Gene3D G3DSA:2.50.20.10 26 208 8.0E-24 T 29-03-2018 A616_RS02855 38d224ad06d2e7f92df1588b1e37d68e 345 SUPERFAMILY SSF89392 30 203 1.45E-15 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A616_RS01160 7a769af464dd29df9ffd4f7dbd9ddacc 69 SMART SM00530 9 64 2.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS01160 7a769af464dd29df9ffd4f7dbd9ddacc 69 SUPERFAMILY SSF47413 5 65 6.7E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS01160 7a769af464dd29df9ffd4f7dbd9ddacc 69 Pfam PF01381 Helix-turn-helix 10 64 7.3E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS01160 7a769af464dd29df9ffd4f7dbd9ddacc 69 Gene3D G3DSA:1.10.260.40 1 69 2.2E-19 T 29-03-2018 A616_RS14050 ab7d1da5035a27a3184a5d8e74858540 357 Pfam PF00534 Glycosyl transferases group 1 168 329 2.4E-38 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS14050 ab7d1da5035a27a3184a5d8e74858540 357 Gene3D G3DSA:3.40.50.2000 164 338 1.4E-42 T 29-03-2018 A616_RS14050 ab7d1da5035a27a3184a5d8e74858540 357 SUPERFAMILY SSF53756 33 354 2.48E-72 T 29-03-2018 A616_RS14050 ab7d1da5035a27a3184a5d8e74858540 357 Pfam PF13439 Glycosyltransferase Family 4 23 157 2.4E-17 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS14050 ab7d1da5035a27a3184a5d8e74858540 357 Gene3D G3DSA:3.40.50.2000 2 163 1.9E-8 T 29-03-2018 A616_RS32310 0bf7b7aaea745c59683953439e50a633 322 SUPERFAMILY SSF81301 5 111 1.05E-8 T 29-03-2018 A616_RS32310 0bf7b7aaea745c59683953439e50a633 322 Gene3D G3DSA:3.30.460.10 1 133 7.2E-10 T 29-03-2018 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 Gene3D G3DSA:3.40.190.10 92 178 5.4E-11 T 29-03-2018 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 Gene3D G3DSA:1.10.10.10 1 91 1.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 SUPERFAMILY SSF46785 2 87 1.25E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 SUPERFAMILY SSF53850 88 295 3.62E-28 T 29-03-2018 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.6E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 Gene3D G3DSA:3.40.190.10 179 264 1.3E-7 T 29-03-2018 A616_RS02520 1d0546ecbcf70819b38debbe9d61d609 304 Pfam PF03466 LysR substrate binding domain 87 289 6.7E-33 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 SUPERFAMILY SSF51735 4 209 2.0E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 Gene3D G3DSA:3.40.50.720 1 215 3.0E-51 T 29-03-2018 A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.0E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.0E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.0E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.0E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 Pfam PF00106 short chain dehydrogenase 4 193 6.0E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02645 2de62d4afed82010c6b6caf9431bb5a2 233 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS17915 322b424f4c98251e913d8a709da4b09b 394 Pfam PF04235 Protein of unknown function (DUF418) 227 388 2.7E-40 T 29-03-2018 IPR007349 Domain of unknown function DUF418 A616_RS28025 1e7019d1acb61576dbc1e3ffcaa8c748 151 Pfam PF05105 Bacteriophage holin family 38 136 2.8E-15 T 29-03-2018 IPR006480 Bacteriophage holin family A616_RS28025 1e7019d1acb61576dbc1e3ffcaa8c748 151 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 40 149 2.7E-13 T 29-03-2018 IPR006480 Bacteriophage holin family A616_RS09170 319640191568e1a58575c57326689b7c 329 SMART SM00382 49 241 2.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS09170 319640191568e1a58575c57326689b7c 329 Pfam PF00005 ABC transporter 41 191 4.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09170 319640191568e1a58575c57326689b7c 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 2.0E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS09170 319640191568e1a58575c57326689b7c 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 5.7E-30 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS09170 319640191568e1a58575c57326689b7c 329 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS09170 319640191568e1a58575c57326689b7c 329 Gene3D G3DSA:3.40.50.300 10 329 1.1E-81 T 29-03-2018 A616_RS09170 319640191568e1a58575c57326689b7c 329 SUPERFAMILY SSF52540 13 263 1.96E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS17435 00146ba62c4d00f298924561c4e55f7b 1916 Pfam PF10145 Phage-related minor tail protein 316 506 1.6E-24 T 29-03-2018 IPR010090 Phage tail tape measure protein A616_RS17435 00146ba62c4d00f298924561c4e55f7b 1916 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 273 584 4.5E-41 T 29-03-2018 IPR010090 Phage tail tape measure protein A616_RS17435 00146ba62c4d00f298924561c4e55f7b 1916 Gene3D G3DSA:1.20.140.50 204 699 8.4E-6 T 29-03-2018 A616_RS21935 b6f3f6a4ecb836f75c44fb6f3b7f3b3c 389 Pfam PF00144 Beta-lactamase 64 373 2.2E-68 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS21935 b6f3f6a4ecb836f75c44fb6f3b7f3b3c 389 Gene3D G3DSA:3.40.710.10 43 389 5.2E-78 T 29-03-2018 A616_RS21935 b6f3f6a4ecb836f75c44fb6f3b7f3b3c 389 SUPERFAMILY SSF56601 51 373 2.67E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 Gene3D G3DSA:1.10.1660.10 1 116 2.9E-16 T 29-03-2018 A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 SUPERFAMILY SSF46955 5 92 5.49E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 SMART SM00422 119 190 4.0E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 SMART SM00422 1 69 2.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 Pfam PF00376 MerR family regulatory protein 5 39 5.5E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 Gene3D G3DSA:1.10.1660.10 117 194 1.2E-19 T 29-03-2018 A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 Pfam PF13411 MerR HTH family regulatory protein 119 181 4.1E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A616_RS08535 fc2cdb1697bc39e498c34a4159bb4293 235 SUPERFAMILY SSF46955 118 212 3.25E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain A616_RS19040 888ad8027ab8fa1fde53dca8f1b263e3 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 465 1.8E-78 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS19040 888ad8027ab8fa1fde53dca8f1b263e3 547 Gene3D G3DSA:3.90.76.10 72 181 8.6E-30 T 29-03-2018 A616_RS19040 888ad8027ab8fa1fde53dca8f1b263e3 547 Gene3D G3DSA:3.40.190.10 182 318 8.1E-36 T 29-03-2018 A616_RS19040 888ad8027ab8fa1fde53dca8f1b263e3 547 PIRSF PIRSF002741 1 547 9.3E-120 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS19040 888ad8027ab8fa1fde53dca8f1b263e3 547 SUPERFAMILY SSF53850 55 542 5.43E-126 T 29-03-2018 A616_RS19040 888ad8027ab8fa1fde53dca8f1b263e3 547 Gene3D G3DSA:3.10.105.10 319 518 2.9E-49 T 29-03-2018 A616_RS14455 b4127b9a8f13fcda1cfc1c214fbd0ee1 397 Pfam PF00155 Aminotransferase class I and II 43 383 7.9E-67 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS14455 b4127b9a8f13fcda1cfc1c214fbd0ee1 397 SUPERFAMILY SSF53383 8 395 9.52E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS14455 b4127b9a8f13fcda1cfc1c214fbd0ee1 397 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 2.2E-194 T 29-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A616_RS14455 b4127b9a8f13fcda1cfc1c214fbd0ee1 397 Gene3D G3DSA:3.90.1150.10 288 396 2.5E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS14455 b4127b9a8f13fcda1cfc1c214fbd0ee1 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A616_RS14455 b4127b9a8f13fcda1cfc1c214fbd0ee1 397 Gene3D G3DSA:3.40.640.10 57 287 4.9E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS19395 a3367c0e1cb7e68420c842c42b1891aa 64 Gene3D G3DSA:3.30.429.10 1 64 4.3E-24 T 29-03-2018 A616_RS19395 a3367c0e1cb7e68420c842c42b1891aa 64 SUPERFAMILY SSF55331 2 62 7.47E-20 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily A616_RS19395 a3367c0e1cb7e68420c842c42b1891aa 64 Pfam PF01361 Tautomerase enzyme 2 55 5.2E-17 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A616_RS19395 a3367c0e1cb7e68420c842c42b1891aa 64 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 62 1.8E-16 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 A616_RS26920 6e872286c277b04d7be338a4b30df80e 170 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 170 25.978 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 A616_RS26920 6e872286c277b04d7be338a4b30df80e 170 Pfam PF03079 ARD/ARD' family 3 168 2.6E-41 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 A616_RS26920 6e872286c277b04d7be338a4b30df80e 170 SUPERFAMILY SSF51182 1 170 1.09E-30 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS26920 6e872286c277b04d7be338a4b30df80e 170 Gene3D G3DSA:2.60.120.10 1 160 1.0E-37 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS13225 36308cb3a2eca4f213d0a19045876840 267 Pfam PF13649 Methyltransferase domain 38 132 6.1E-25 T 29-03-2018 A616_RS13225 36308cb3a2eca4f213d0a19045876840 267 SUPERFAMILY SSF53335 22 198 5.88E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS13225 36308cb3a2eca4f213d0a19045876840 267 Gene3D G3DSA:3.40.50.150 4 259 1.6E-40 T 29-03-2018 A616_RS22225 01794f1b1791f3e75f6dd988a12b734b 804 SUPERFAMILY SSF52540 176 802 6.23E-125 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22225 01794f1b1791f3e75f6dd988a12b734b 804 Gene3D G3DSA:3.40.50.300 168 447 1.6E-54 T 29-03-2018 A616_RS22225 01794f1b1791f3e75f6dd988a12b734b 804 Pfam PF13361 UvrD-like helicase C-terminal domain 452 782 9.8E-42 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A616_RS22225 01794f1b1791f3e75f6dd988a12b734b 804 Pfam PF00580 UvrD/REP helicase N-terminal domain 179 446 8.3E-64 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A616_RS22225 01794f1b1791f3e75f6dd988a12b734b 804 Gene3D G3DSA:3.40.50.300 448 804 4.7E-50 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 Pfam PF00117 Glutamine amidotransferase class-I 181 357 5.1E-43 T 29-03-2018 IPR017926 Glutamine amidotransferase A616_RS29355 948919b42228949266a6025625c35204 368 SUPERFAMILY SSF52317 148 359 1.63E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 221 230 1.8E-11 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 248 259 1.8E-11 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 334 347 1.8E-11 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 SUPERFAMILY SSF52021 10 150 1.03E-49 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 218 232 1.7E-31 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 290 301 1.7E-31 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 265 282 1.7E-31 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 179 193 1.7E-31 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 248 264 1.7E-31 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 SMART SM01097 9 139 4.3E-67 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29355 948919b42228949266a6025625c35204 368 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 12 360 1.2E-134 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00097 Anthranilate synthase component II signature 248 259 6.6E-7 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00097 Anthranilate synthase component II signature 334 347 6.6E-7 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 PRINTS PR00097 Anthranilate synthase component II signature 221 230 6.6E-7 T 29-03-2018 A616_RS29355 948919b42228949266a6025625c35204 368 Gene3D G3DSA:3.40.50.880 161 367 1.1E-36 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS29355 948919b42228949266a6025625c35204 368 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 11 138 3.5E-46 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29355 948919b42228949266a6025625c35204 368 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 9 363 43.292 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS29355 948919b42228949266a6025625c35204 368 Gene3D G3DSA:3.50.30.20 8 157 7.7E-51 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A616_RS12145 ffa69117a8f990cad22a6b9446c826db 262 Pfam PF00005 ABC transporter 18 168 3.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12145 ffa69117a8f990cad22a6b9446c826db 262 SUPERFAMILY SSF52540 2 234 3.01E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12145 ffa69117a8f990cad22a6b9446c826db 262 Gene3D G3DSA:3.40.50.300 1 238 1.3E-51 T 29-03-2018 A616_RS12145 ffa69117a8f990cad22a6b9446c826db 262 SMART SM00382 27 219 6.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS12145 ffa69117a8f990cad22a6b9446c826db 262 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS11315 731765aae10e607396496ab368cc16b8 551 Gene3D G3DSA:3.40.190.10 222 316 2.4E-36 T 29-03-2018 A616_RS11315 731765aae10e607396496ab368cc16b8 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 471 6.6E-114 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS11315 731765aae10e607396496ab368cc16b8 551 SUPERFAMILY SSF53850 54 549 7.56E-154 T 29-03-2018 A616_RS11315 731765aae10e607396496ab368cc16b8 551 Gene3D G3DSA:3.10.105.10 317 523 1.1E-64 T 29-03-2018 A616_RS11315 731765aae10e607396496ab368cc16b8 551 PIRSF PIRSF002741 2 551 3.3E-140 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS11315 731765aae10e607396496ab368cc16b8 551 Gene3D G3DSA:3.90.76.10 62 221 2.3E-39 T 29-03-2018 A616_RS21075 e867142634be88d4a464bec8679b1583 945 SUPERFAMILY SSF88713 3 412 1.48E-115 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS21075 e867142634be88d4a464bec8679b1583 945 SUPERFAMILY SSF53756 552 935 5.89E-101 T 29-03-2018 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Gene3D G3DSA:1.20.1430.10 414 531 1.6E-35 T 29-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Gene3D G3DSA:3.40.50.2000 750 920 1.0E-54 T 29-03-2018 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Pfam PF09210 Domain of unknown function (DUF1957) 423 525 1.9E-28 T 29-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Pfam PF00534 Glycosyl transferases group 1 746 911 1.3E-48 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Gene3D G3DSA:3.40.50.2000 544 749 1.1E-20 T 29-03-2018 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Pfam PF13439 Glycosyltransferase Family 4 564 738 2.0E-32 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS21075 e867142634be88d4a464bec8679b1583 945 SUPERFAMILY SSF88688 416 527 5.89E-32 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain A616_RS21075 e867142634be88d4a464bec8679b1583 945 Pfam PF03065 Glycosyl hydrolase family 57 8 360 1.8E-52 T 29-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A616_RS21075 e867142634be88d4a464bec8679b1583 945 Gene3D G3DSA:3.20.110.10 1 412 8.0E-109 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 Gene3D G3DSA:3.40.50.1860 1 117 8.7E-34 T 29-03-2018 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 193 203 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 SUPERFAMILY SSF53681 118 229 3.27E-34 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 SUPERFAMILY SSF53681 1 116 4.8E-37 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 5.9E-60 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 Gene3D G3DSA:3.40.50.1860 118 215 1.8E-26 T 29-03-2018 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 229 8.5E-72 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A616_RS24715 5a5b3f8c1d6457ac66c6abef18b287f2 230 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS05985 47ebbb85e2ecd20d4a833107e27e3b76 182 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 172 9.0E-44 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A616_RS05985 47ebbb85e2ecd20d4a833107e27e3b76 182 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 6.8E-60 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A616_RS05985 47ebbb85e2ecd20d4a833107e27e3b76 182 Pfam PF01923 Cobalamin adenosyltransferase 3 168 1.7E-60 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A616_RS05985 47ebbb85e2ecd20d4a833107e27e3b76 182 SUPERFAMILY SSF89028 1 174 7.85E-61 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 A616_RS05985 47ebbb85e2ecd20d4a833107e27e3b76 182 Gene3D G3DSA:1.20.1200.10 12 182 3.7E-60 T 29-03-2018 A616_RS07040 f715b5ef5f2ddb897daacb44d298055e 321 Pfam PF00892 EamA-like transporter family 158 296 3.0E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS07040 f715b5ef5f2ddb897daacb44d298055e 321 Pfam PF00892 EamA-like transporter family 14 144 5.2E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS07040 f715b5ef5f2ddb897daacb44d298055e 321 SUPERFAMILY SSF103481 46 147 5.23E-8 T 29-03-2018 A616_RS07040 f715b5ef5f2ddb897daacb44d298055e 321 SUPERFAMILY SSF103481 197 299 8.24E-16 T 29-03-2018 A616_RS32000 4251beafdbc7324d8279fc8bcb31abaf 285 Gene3D G3DSA:3.40.50.150 5 270 3.8E-42 T 29-03-2018 A616_RS32000 4251beafdbc7324d8279fc8bcb31abaf 285 Pfam PF04072 Leucine carboxyl methyltransferase 13 190 7.4E-49 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 A616_RS32000 4251beafdbc7324d8279fc8bcb31abaf 285 SUPERFAMILY SSF53335 10 282 1.16E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS32000 4251beafdbc7324d8279fc8bcb31abaf 285 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 265 1.1E-51 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 A616_RS01330 27cf8d73956d448054f8c223775f15ed 171 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 3 148 2.0E-4 T 29-03-2018 A616_RS01330 27cf8d73956d448054f8c223775f15ed 171 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 8 166 29.974 T 29-03-2018 IPR022973 Ribosomal protein L10 A616_RS01330 27cf8d73956d448054f8c223775f15ed 171 Pfam PF00466 Ribosomal protein L10 10 106 4.3E-29 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A616_RS01330 27cf8d73956d448054f8c223775f15ed 171 ProSitePatterns PS01109 Ribosomal protein L10 signature. 13 47 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01330 27cf8d73956d448054f8c223775f15ed 171 SUPERFAMILY SSF160369 9 165 1.57E-55 T 29-03-2018 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 Gene3D G3DSA:3.30.70.980 172 239 6.7E-11 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 SUPERFAMILY SSF75625 1 238 7.46E-81 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 7.9E-71 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 Pfam PF01709 Transcriptional regulator 4 235 1.1E-80 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 Gene3D G3DSA:3.30.70.980 80 171 6.5E-26 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 Gene3D G3DSA:1.10.10.200 2 76 2.7E-26 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.448 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS08570 bde2ed78a1c84cff99f3f33169495f7f 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 56.701 T 29-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN A616_RS01075 7909bd8bc91dd9cd512b925996682c1e 552 PIRSF PIRSF002741 3 552 4.7E-111 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS01075 7909bd8bc91dd9cd512b925996682c1e 552 Gene3D G3DSA:3.40.190.10 186 319 4.4E-32 T 29-03-2018 A616_RS01075 7909bd8bc91dd9cd512b925996682c1e 552 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 474 9.0E-78 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS01075 7909bd8bc91dd9cd512b925996682c1e 552 Gene3D G3DSA:3.90.76.10 76 185 3.1E-30 T 29-03-2018 A616_RS01075 7909bd8bc91dd9cd512b925996682c1e 552 SUPERFAMILY SSF53850 49 548 8.81E-126 T 29-03-2018 A616_RS01075 7909bd8bc91dd9cd512b925996682c1e 552 Gene3D G3DSA:3.10.105.10 320 524 6.1E-53 T 29-03-2018 A616_RS07765 65f3009f19e699f938f3754cf6870885 104 Pfam PF12986 Domain of unknown function (DUF3870) 9 99 7.2E-18 T 29-03-2018 IPR024617 Domain of unknown function DUF3870 A616_RS24455 578e615c4c4d030188ce1d164147b721 202 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 14 198 9.1E-30 T 29-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane A616_RS24455 578e615c4c4d030188ce1d164147b721 202 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 16 198 2.0E-42 T 29-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane A616_RS26515 392a14a04db9925ec5c707f14d17b873 372 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 371 5.6E-61 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS26515 392a14a04db9925ec5c707f14d17b873 372 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 369 7.6E-20 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS01575 b4f25353b42e214948a42af07ec4182a 246 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 49 234 8.3E-49 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS01575 b4f25353b42e214948a42af07ec4182a 246 SMART SM00646 123 234 3.7E-30 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS01575 b4f25353b42e214948a42af07ec4182a 246 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 48 235 2.4E-71 T 29-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD A616_RS01575 b4f25353b42e214948a42af07ec4182a 246 Gene3D G3DSA:3.40.630.40 44 242 3.0E-54 T 29-03-2018 A616_RS01575 b4f25353b42e214948a42af07ec4182a 246 SUPERFAMILY SSF53187 47 237 1.66E-48 T 29-03-2018 A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 SUPERFAMILY SSF46785 9 80 5.14E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 SUPERFAMILY SSF51735 84 206 1.57E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 SMART SM00881 81 181 3.0E-22 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 Gene3D G3DSA:1.10.10.10 5 72 6.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 Gene3D G3DSA:3.40.50.720 73 188 1.6E-21 T 29-03-2018 A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 Pfam PF02629 CoA binding domain 84 179 2.9E-24 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 Pfam PF06971 Putative DNA-binding protein N-terminus 6 53 8.4E-20 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 A616_RS13980 ab15d3bfed294be55d6659dff886d5e5 207 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 207 32.277 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 A616_RS17095 348c6774f67edf43e361c04ee31f5871 75 Gene3D G3DSA:2.10.260.10 1 75 4.9E-7 T 29-03-2018 A616_RS11795 d59036e79e1968a07fb9ce5d94c35ae8 242 Gene3D G3DSA:3.20.20.190 1 242 4.5E-71 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS11795 d59036e79e1968a07fb9ce5d94c35ae8 242 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 233 3.7E-42 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A616_RS11795 d59036e79e1968a07fb9ce5d94c35ae8 242 SUPERFAMILY SSF51695 3 239 9.68E-72 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS27935 bd1e40c8d8591c8edbe3171c5d527da9 182 SUPERFAMILY SSF46785 9 160 3.32E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27935 bd1e40c8d8591c8edbe3171c5d527da9 182 PIRSF PIRSF006707 1 182 2.0E-49 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type A616_RS27935 bd1e40c8d8591c8edbe3171c5d527da9 182 Gene3D G3DSA:1.10.10.10 1 156 3.8E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22210 dd352ef22cdf54316ed5d474f479540c 309 Pfam PF00753 Metallo-beta-lactamase superfamily 17 209 1.9E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22210 dd352ef22cdf54316ed5d474f479540c 309 SUPERFAMILY SSF56281 15 256 1.31E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22210 dd352ef22cdf54316ed5d474f479540c 309 Gene3D G3DSA:3.60.15.10 5 244 3.0E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22210 dd352ef22cdf54316ed5d474f479540c 309 SMART SM00849 19 210 4.2E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 SUPERFAMILY SSF52172 1 171 8.06E-38 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 SMART SM00448 2 111 6.6E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 SMART SM00862 143 215 6.8E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 215 4.6E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 Pfam PF00072 Response regulator receiver domain 4 112 2.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 Gene3D G3DSA:3.40.50.2300 1 120 9.2E-34 T 29-03-2018 A616_RS16100 bf4d09d3baf6d9ae124e81b96ec8fa28 217 Gene3D G3DSA:1.10.10.10 121 217 2.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 Gene3D G3DSA:2.30.40.10 487 549 1.2E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 Gene3D G3DSA:3.20.20.140 78 486 2.0E-36 T 29-03-2018 A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 SUPERFAMILY SSF51338 500 547 7.88E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 SUPERFAMILY SSF51338 10 69 7.88E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 Pfam PF07969 Amidohydrolase family 57 541 2.3E-112 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 SUPERFAMILY SSF51556 68 130 1.4E-41 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 SUPERFAMILY SSF51556 210 500 1.4E-41 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS24790 7cd688fd5f8b35efae6afcae67c913ec 608 Gene3D G3DSA:2.30.40.10 7 77 1.7E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS12320 d732b6b368b364e9ba2c8f68a5ee3fa6 353 Pfam PF13487 HD domain 180 234 4.3E-10 T 29-03-2018 A616_RS12320 d732b6b368b364e9ba2c8f68a5ee3fa6 353 Gene3D G3DSA:1.10.3210.10 120 291 1.9E-25 T 29-03-2018 A616_RS12320 d732b6b368b364e9ba2c8f68a5ee3fa6 353 SMART SM00471 123 253 3.3E-5 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS12320 d732b6b368b364e9ba2c8f68a5ee3fa6 353 SUPERFAMILY SSF109604 124 281 4.71E-20 T 29-03-2018 A616_RS26445 21436559b83350c23ba26713b83892e4 144 Gene3D G3DSA:1.20.120.580 1 144 2.8E-27 T 29-03-2018 IPR008201 Protein of unknown function DUF86 A616_RS26445 21436559b83350c23ba26713b83892e4 144 Pfam PF01934 Protein of unknown function DUF86 18 139 2.4E-18 T 29-03-2018 IPR008201 Protein of unknown function DUF86 A616_RS18045 eda04f0c2b4e9e5b49be213b70882163 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A616_RS18045 eda04f0c2b4e9e5b49be213b70882163 490 Gene3D G3DSA:3.40.309.10 272 460 2.4E-64 T 29-03-2018 A616_RS18045 eda04f0c2b4e9e5b49be213b70882163 490 Pfam PF00171 Aldehyde dehydrogenase family 20 486 4.8E-158 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS18045 eda04f0c2b4e9e5b49be213b70882163 490 Gene3D G3DSA:3.40.605.10 2 271 4.8E-89 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS18045 eda04f0c2b4e9e5b49be213b70882163 490 SUPERFAMILY SSF53720 8 489 7.72E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS18045 eda04f0c2b4e9e5b49be213b70882163 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS31240 3742965a8bde2fc55b8a85a6127631eb 421 Gene3D G3DSA:3.40.50.300 125 398 6.1E-10 T 29-03-2018 A616_RS31240 3742965a8bde2fc55b8a85a6127631eb 421 SUPERFAMILY SSF52540 127 150 7.14E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31240 3742965a8bde2fc55b8a85a6127631eb 421 SUPERFAMILY SSF52540 287 343 7.14E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31240 3742965a8bde2fc55b8a85a6127631eb 421 SUPERFAMILY SSF52540 190 256 7.14E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23835 45b69da926d8a88b34f0cb3e5af2993a 160 Gene3D G3DSA:1.20.120.450 1 151 1.4E-15 T 29-03-2018 A616_RS23835 45b69da926d8a88b34f0cb3e5af2993a 160 SUPERFAMILY SSF109854 12 151 2.93E-18 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS23835 45b69da926d8a88b34f0cb3e5af2993a 160 Pfam PF12867 DinB superfamily 22 146 4.0E-15 T 29-03-2018 IPR024775 DinB-like domain A616_RS11850 cc816cc1ed7b31695bd991c26e66cd38 276 Gene3D G3DSA:3.30.457.10 79 141 1.9E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS11850 cc816cc1ed7b31695bd991c26e66cd38 276 Gene3D G3DSA:3.30.457.10 34 78 2.5E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS11850 cc816cc1ed7b31695bd991c26e66cd38 276 Gene3D G3DSA:3.30.457.10 142 273 2.4E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS11850 cc816cc1ed7b31695bd991c26e66cd38 276 Pfam PF07833 Copper amine oxidase N-terminal domain 68 159 4.0E-34 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS11850 cc816cc1ed7b31695bd991c26e66cd38 276 SUPERFAMILY SSF55383 70 154 1.83E-27 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS17540 7087cd3ad242dac5b509d987682e8b2d 67 Gene3D G3DSA:1.10.260.40 1 52 9.9E-4 T 29-03-2018 A616_RS19150 4b8c779d53baf781837545691f457da9 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 2 21 1.6E-5 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS19150 4b8c779d53baf781837545691f457da9 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 25 4.2E-7 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 SUPERFAMILY SSF53383 114 475 4.62E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.1E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 Gene3D G3DSA:3.90.1150.10 382 477 4.1E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 SMART SM00345 17 76 1.0E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 Pfam PF00155 Aminotransferase class I and II 118 469 4.6E-38 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 8.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 8.1E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 Gene3D G3DSA:3.40.640.10 140 381 2.7E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 Gene3D G3DSA:1.10.10.10 1 78 1.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26685 53e98182d33d87dc5bfd2c9b292f2e52 478 SUPERFAMILY SSF46785 6 78 5.29E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02840 395a05b84e90568798ea982eab3fa5bd 83 Gene3D G3DSA:3.40.30.10 2 83 7.6E-15 T 29-03-2018 A616_RS02840 395a05b84e90568798ea982eab3fa5bd 83 SUPERFAMILY SSF52833 3 81 3.33E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS02840 395a05b84e90568798ea982eab3fa5bd 83 Pfam PF00462 Glutaredoxin 5 59 1.1E-7 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A616_RS12150 45a1e00f507046431efe15c05d024f99 229 SMART SM00849 25 193 4.0E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12150 45a1e00f507046431efe15c05d024f99 229 SUPERFAMILY SSF56281 8 224 2.84E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12150 45a1e00f507046431efe15c05d024f99 229 Pfam PF00753 Metallo-beta-lactamase superfamily 25 160 2.1E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12150 45a1e00f507046431efe15c05d024f99 229 Gene3D G3DSA:3.60.15.10 2 229 1.4E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS28770 a0052d12d8904c98d9d6a8670b5293c1 441 Pfam PF06527 TniQ 25 169 5.8E-17 T 29-03-2018 IPR009492 TniQ A616_RS28770 a0052d12d8904c98d9d6a8670b5293c1 441 Gene3D G3DSA:1.10.260.40 235 406 9.5E-7 T 29-03-2018 A616_RS28770 a0052d12d8904c98d9d6a8670b5293c1 441 SUPERFAMILY SSF47413 239 298 3.44E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS07540 92ccf023fea624ae3de0c770c528bda0 320 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 12 319 2.9E-142 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A616_RS07540 92ccf023fea624ae3de0c770c528bda0 320 Gene3D G3DSA:3.40.50.300 10 319 4.0E-52 T 29-03-2018 A616_RS07540 92ccf023fea624ae3de0c770c528bda0 320 Hamap MF_00215 Pantothenate kinase [coaA]. 1 320 179.344 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A616_RS07540 92ccf023fea624ae3de0c770c528bda0 320 PIRSF PIRSF000545 2 320 6.9E-147 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A616_RS07540 92ccf023fea624ae3de0c770c528bda0 320 SUPERFAMILY SSF52540 11 318 1.33E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS07540 92ccf023fea624ae3de0c770c528bda0 320 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 246 4.4E-10 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 A616_RS31250 1b86d4fd7ec26744aaf7b2868c14260e 424 SUPERFAMILY SSF53300 91 288 4.75E-31 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31250 1b86d4fd7ec26744aaf7b2868c14260e 424 Gene3D G3DSA:3.40.50.410 107 294 6.7E-33 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31250 1b86d4fd7ec26744aaf7b2868c14260e 424 Pfam PF00092 von Willebrand factor type A domain 115 283 4.4E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS31250 1b86d4fd7ec26744aaf7b2868c14260e 424 SMART SM00327 113 290 5.6E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS30770 a2d2f8a05e34da9e898a7979ed4c7afd 216 Pfam PF00936 BMC domain 34 105 4.1E-12 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30770 a2d2f8a05e34da9e898a7979ed4c7afd 216 SMART SM00877 144 213 8.4E-6 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30770 a2d2f8a05e34da9e898a7979ed4c7afd 216 SMART SM00877 33 119 1.3E-7 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30770 a2d2f8a05e34da9e898a7979ed4c7afd 216 PIRSF PIRSF012290 1 216 6.4E-79 T 29-03-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 A616_RS30770 a2d2f8a05e34da9e898a7979ed4c7afd 216 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 4 215 6.4E-109 T 29-03-2018 IPR030983 Ethanolamine utilization protein EutL GO:0005198 A616_RS30770 a2d2f8a05e34da9e898a7979ed4c7afd 216 SUPERFAMILY SSF143414 155 209 7.46E-5 T 29-03-2018 A616_RS08680 552a1ad031fb64f38c2ff9907799713d 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 7.1E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS08680 552a1ad031fb64f38c2ff9907799713d 130 SUPERFAMILY SSF54593 1 126 5.5E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS08680 552a1ad031fb64f38c2ff9907799713d 130 Gene3D G3DSA:3.10.180.10 1 130 1.0E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS30400 9280bc113df2a580abbb7edf3fbaf14d 247 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 66 219 7.7E-36 T 29-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 A616_RS30400 9280bc113df2a580abbb7edf3fbaf14d 247 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 12 32 3.3E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A616_RS02845 aa5e673df1618108359c60ad6b7034d4 82 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 45 81 3.3E-9 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A616_RS02845 aa5e673df1618108359c60ad6b7034d4 82 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 3 47 1.1E-6 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A616_RS02845 aa5e673df1618108359c60ad6b7034d4 82 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 41 79 5.0E-8 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 SUPERFAMILY SSF46785 23 137 3.86E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 SMART SM00347 22 122 2.3E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 Gene3D G3DSA:1.10.10.10 24 100 9.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 2.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 2.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 2.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 2.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 Pfam PF01047 MarR family 29 86 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 Gene3D G3DSA:1.10.287.100 101 139 5.5E-4 T 29-03-2018 A616_RS25060 93cad5f5be6a64a4c8388aa80b323771 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 61 95 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A616_RS01155 f41492f0fd169157ddb20bec8e32a36f 176 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 132 1.2E-43 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A616_RS01155 f41492f0fd169157ddb20bec8e32a36f 176 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 132 5.3E-38 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A616_RS01155 f41492f0fd169157ddb20bec8e32a36f 176 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A616_RS01155 f41492f0fd169157ddb20bec8e32a36f 176 Gene3D G3DSA:3.30.70.560 1 165 2.6E-55 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A616_RS01155 f41492f0fd169157ddb20bec8e32a36f 176 SUPERFAMILY SSF55083 4 151 1.11E-50 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A616_RS09065 79c35675ea3a74184413fa591e8711f1 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 2.9E-96 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A616_RS09065 79c35675ea3a74184413fa591e8711f1 311 SUPERFAMILY SSF51556 1 307 9.52E-78 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS09065 79c35675ea3a74184413fa591e8711f1 311 Gene3D G3DSA:3.20.20.140 2 308 1.6E-94 T 29-03-2018 A616_RS26595 a74e8fa7f3323c147f5a8147d256e128 396 Pfam PF07690 Major Facilitator Superfamily 33 350 2.8E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS26595 a74e8fa7f3323c147f5a8147d256e128 396 SUPERFAMILY SSF103473 6 391 2.49E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS26595 a74e8fa7f3323c147f5a8147d256e128 396 Gene3D G3DSA:1.20.1250.20 3 181 2.7E-20 T 29-03-2018 A616_RS26595 a74e8fa7f3323c147f5a8147d256e128 396 Gene3D G3DSA:1.20.1250.20 201 394 1.3E-13 T 29-03-2018 A616_RS07985 ae55f7a0d75ba1db28dec84796b25492 376 Pfam PF01594 AI-2E family transporter 18 361 1.9E-56 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like A616_RS07985 ae55f7a0d75ba1db28dec84796b25492 376 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 16 364 1.2E-98 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Pfam PF00041 Fibronectin type III domain 563 635 8.5E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Pfam PF00041 Fibronectin type III domain 470 541 7.8E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SUPERFAMILY SSF54556 344 414 2.82E-21 T 29-03-2018 IPR029070 Chitinase insertion domain A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SUPERFAMILY SSF51055 655 697 3.4E-14 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Gene3D G3DSA:2.10.10.20 655 698 9.3E-15 T 29-03-2018 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Gene3D G3DSA:3.20.20.80 12 461 3.6E-107 T 29-03-2018 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SUPERFAMILY SSF51445 45 344 2.74E-106 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SUPERFAMILY SSF51445 415 446 2.74E-106 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SMART SM00060 562 635 1.1E-13 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SMART SM00060 468 541 2.3E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Gene3D G3DSA:2.60.40.10 462 551 4.7E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Gene3D G3DSA:2.60.40.10 552 643 2.1E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 PRINTS PR00014 Fibronectin type III repeat signature 604 622 5.4E-6 T 29-03-2018 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 PRINTS PR00014 Fibronectin type III repeat signature 494 504 5.4E-6 T 29-03-2018 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 PRINTS PR00014 Fibronectin type III repeat signature 622 636 5.4E-6 T 29-03-2018 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 PRINTS PR00014 Fibronectin type III repeat signature 203 212 5.4E-6 T 29-03-2018 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SUPERFAMILY SSF49265 467 638 2.35E-28 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 ProSitePatterns PS01095 Chitinases family 18 active site. 202 210 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SMART SM00636 51 443 1.1E-153 T 29-03-2018 IPR011583 Chitinase II GO:0008061 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 Pfam PF00704 Glycosyl hydrolases family 18 52 443 6.9E-99 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS09895 acfe08687cc9ac5ec02d4c20a4f764a2 744 SMART SM00495 653 699 4.8E-11 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A616_RS14695 1eb744d805bb6da390f2c9010df57d4d 356 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 192 355 2.2E-26 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS14695 1eb744d805bb6da390f2c9010df57d4d 356 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 355 1.4E-64 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 SUPERFAMILY SSF56059 1 342 2.35E-95 T 29-03-2018 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 Pfam PF00391 PEP-utilising enzyme, mobile domain 795 866 1.2E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 Gene3D G3DSA:3.30.470.20 184 314 1.9E-42 T 29-03-2018 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 316 5.1E-95 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 Gene3D G3DSA:3.50.30.10 770 871 1.3E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 SUPERFAMILY SSF52009 766 869 2.22E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A616_RS21160 ce2de985f74b11923df98f51211781fa 871 Gene3D G3DSA:3.30.1490.20 1 183 1.3E-54 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.0E-16 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.0E-16 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.0E-16 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 5.0E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 Gene3D G3DSA:3.30.1340.10 1 85 1.0E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.0E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 SUPERFAMILY SSF55594 1 84 1.01E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS00370 a475bb04a2ec556a315520f90fd322e3 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 Pfam PF01259 SAICAR synthetase 7 232 4.2E-68 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 SUPERFAMILY SSF56104 3 235 3.92E-83 T 29-03-2018 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 Gene3D G3DSA:3.30.470.20 94 221 2.9E-50 T 29-03-2018 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 Gene3D G3DSA:3.30.200.20 1 93 4.0E-28 T 29-03-2018 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 235 3.2E-75 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A616_RS03545 19d6188a83d86cbdac1eef01264aa8a0 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 33.595 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.4E-6 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 4.4E-6 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 4.4E-6 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.4E-13 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-13 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.4E-13 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.4E-13 T 29-03-2018 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 Gene3D G3DSA:3.50.50.60 94 242 1.7E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 SUPERFAMILY SSF51905 3 328 3.03E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 5.0E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 Gene3D G3DSA:3.50.50.60 1 93 2.1E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10590 9c542dfbed43d5a0a6e446fc49e270ad 392 Gene3D G3DSA:3.50.50.60 262 339 2.0E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS01515 ebf7bd147b2bfc8d3a8ef1400aeb91d1 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 7.8E-40 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A616_RS01515 ebf7bd147b2bfc8d3a8ef1400aeb91d1 72 SMART SM00316 2 72 1.1E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS01515 ebf7bd147b2bfc8d3a8ef1400aeb91d1 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 3.1E-29 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A616_RS01515 ebf7bd147b2bfc8d3a8ef1400aeb91d1 72 Gene3D G3DSA:2.40.50.140 1 72 1.4E-38 T 29-03-2018 A616_RS01515 ebf7bd147b2bfc8d3a8ef1400aeb91d1 72 SUPERFAMILY SSF50249 1 71 2.35E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS01515 ebf7bd147b2bfc8d3a8ef1400aeb91d1 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.483 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A616_RS28730 2a20c53652de7422da34536300a18746 448 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 421 1.4E-159 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A616_RS28730 2a20c53652de7422da34536300a18746 448 Pfam PF05525 Branched-chain amino acid transport protein 10 433 9.2E-163 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A616_RS05235 3d9bfd0c80247f6d12aee15cb61e2946 312 Pfam PF08664 YcbB domain 161 299 9.8E-50 T 29-03-2018 IPR013972 YcbB domain A616_RS05235 3d9bfd0c80247f6d12aee15cb61e2946 312 Gene3D G3DSA:3.40.50.2300 1 293 1.5E-23 T 29-03-2018 A616_RS05235 3d9bfd0c80247f6d12aee15cb61e2946 312 SUPERFAMILY SSF52172 4 131 3.56E-24 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS05235 3d9bfd0c80247f6d12aee15cb61e2946 312 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05235 3d9bfd0c80247f6d12aee15cb61e2946 312 SMART SM00448 1 113 1.5E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS22430 b2eecb5c3c1c0ebef23f545d0a818f2e 317 SUPERFAMILY SSF53613 10 286 1.39E-49 T 29-03-2018 IPR029056 Ribokinase-like A616_RS22430 b2eecb5c3c1c0ebef23f545d0a818f2e 317 Pfam PF00294 pfkB family carbohydrate kinase 9 289 1.1E-37 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB A616_RS22430 b2eecb5c3c1c0ebef23f545d0a818f2e 317 Gene3D G3DSA:3.40.1190.20 9 295 3.1E-46 T 29-03-2018 IPR029056 Ribokinase-like A616_RS22430 b2eecb5c3c1c0ebef23f545d0a818f2e 317 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 42 66 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A616_RS21840 4f502a0d85458be64ead1641aebff262 205 PIRSF PIRSF000883 1 186 3.6E-28 T 29-03-2018 IPR011152 Phosphoesterase MJ0912 A616_RS21840 4f502a0d85458be64ead1641aebff262 205 SUPERFAMILY SSF56300 4 172 1.9E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS21840 4f502a0d85458be64ead1641aebff262 205 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 144 2.3E-12 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A616_RS21840 4f502a0d85458be64ead1641aebff262 205 Gene3D G3DSA:3.60.21.10 1 183 3.7E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10285 52270563699ef17266cd40eedf334fff 179 SUPERFAMILY SSF56300 1 152 5.28E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10285 52270563699ef17266cd40eedf334fff 179 Gene3D G3DSA:3.60.21.10 1 171 8.2E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS10285 52270563699ef17266cd40eedf334fff 179 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 144 1.6E-32 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A616_RS10285 52270563699ef17266cd40eedf334fff 179 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 141 1.8E-26 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 PIRSF PIRSF002599 1 66 7.1E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.9E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 SUPERFAMILY SSF50249 1 65 2.1E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 SMART SM00357 3 66 1.0E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 PRINTS PR00050 Cold shock protein signature 24 33 8.8E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 PRINTS PR00050 Cold shock protein signature 4 19 8.8E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 PRINTS PR00050 Cold shock protein signature 39 57 8.8E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS10530 65ba5a0aef28e9338ef6341eb01c755d 66 Gene3D G3DSA:2.40.50.140 1 66 2.6E-29 T 29-03-2018 A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.8E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 SUPERFAMILY SSF46689 3 75 4.46E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 SUPERFAMILY SSF48498 87 194 9.24E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS24060 a14e02d37f5fdbb10fecaf98905f9709 197 Gene3D G3DSA:1.10.357.10 1 197 3.7E-28 T 29-03-2018 A616_RS07805 18ce38e7332c7b895196e2dd93ef897a 740 Gene3D G3DSA:2.60.40.1190 449 715 7.1E-13 T 29-03-2018 A616_RS07805 18ce38e7332c7b895196e2dd93ef897a 740 Gene3D G3DSA:3.20.20.80 69 448 3.7E-31 T 29-03-2018 A616_RS07805 18ce38e7332c7b895196e2dd93ef897a 740 SUPERFAMILY SSF51445 63 412 1.48E-19 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS22525 d26d0f0b2e610ed3c0dd3d42df0882d0 386 Gene3D G3DSA:2.60.120.10 213 360 2.9E-32 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS22525 d26d0f0b2e610ed3c0dd3d42df0882d0 386 Gene3D G3DSA:2.60.120.10 40 211 7.7E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS22525 d26d0f0b2e610ed3c0dd3d42df0882d0 386 SUPERFAMILY SSF51182 7 382 2.03E-95 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS22525 d26d0f0b2e610ed3c0dd3d42df0882d0 386 Pfam PF04209 homogentisate 1,2-dioxygenase 85 382 2.0E-22 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 A616_RS08860 70e31c491155c020a5a54174835e162a 414 Pfam PF15609 Phosphoribosyl transferase 1 217 1.2E-74 T 29-03-2018 A616_RS08860 70e31c491155c020a5a54174835e162a 414 SUPERFAMILY SSF53271 78 207 1.7E-9 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS08860 70e31c491155c020a5a54174835e162a 414 Gene3D G3DSA:3.40.50.2020 1 220 9.5E-20 T 29-03-2018 A616_RS08860 70e31c491155c020a5a54174835e162a 414 PIRSF PIRSF020967 40 392 2.6E-37 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 A616_RS08860 70e31c491155c020a5a54174835e162a 414 PIRSF PIRSF020967 1 43 6.1E-9 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 A616_RS08860 70e31c491155c020a5a54174835e162a 414 Pfam PF12500 TRSP domain C terminus to PRTase_2 275 400 1.0E-35 T 29-03-2018 IPR022537 TRSP domain A616_RS02595 53e2d4531d224eebef063b024672d9b2 312 Gene3D G3DSA:1.10.8.300 197 304 1.8E-31 T 29-03-2018 A616_RS02595 53e2d4531d224eebef063b024672d9b2 312 PIRSF PIRSF002849 1 309 1.0E-127 T 29-03-2018 A616_RS02595 53e2d4531d224eebef063b024672d9b2 312 SUPERFAMILY SSF52540 3 282 7.31E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02595 53e2d4531d224eebef063b024672d9b2 312 Gene3D G3DSA:3.40.50.300 17 183 5.9E-26 T 29-03-2018 A616_RS02595 53e2d4531d224eebef063b024672d9b2 312 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 36 166 1.1E-61 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A616_RS31215 5306de381202c8bb341bfb160185320d 118 SUPERFAMILY SSF52172 1 117 1.85E-37 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS31215 5306de381202c8bb341bfb160185320d 118 Pfam PF00072 Response regulator receiver domain 4 114 1.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS31215 5306de381202c8bb341bfb160185320d 118 Gene3D G3DSA:3.40.50.2300 1 118 7.2E-35 T 29-03-2018 A616_RS31215 5306de381202c8bb341bfb160185320d 118 SMART SM00448 2 114 4.0E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.4E-15 T 29-03-2018 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 SUPERFAMILY SSF46785 1 60 1.18E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.7E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.7E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.7E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 Pfam PF01037 Lrp/AsnC ligand binding domain 74 117 9.0E-10 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 Gene3D G3DSA:1.10.10.10 1 50 6.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 SMART SM00344 1 105 1.4E-38 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 Gene3D G3DSA:3.30.70.920 51 139 3.8E-13 T 29-03-2018 A616_RS08270 38cb279eb208068e23c0ff8586ede478 144 SUPERFAMILY SSF54909 66 135 3.35E-11 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 Gene3D G3DSA:1.20.1070.10 3 32 1.3E-12 T 29-03-2018 A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 Gene3D G3DSA:2.60.40.420 33 155 1.8E-25 T 29-03-2018 IPR008972 Cupredoxin A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 SUPERFAMILY SSF49503 59 154 1.94E-31 T 29-03-2018 IPR008972 Cupredoxin A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 100 148 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 137 154 1.7E-6 T 29-03-2018 A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 75 96 1.7E-6 T 29-03-2018 A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 1.7E-6 T 29-03-2018 A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 PRINTS PR01166 Cytochrome c oxidase subunit II signature 2 14 1.7E-6 T 29-03-2018 A616_RS02380 aba85ba016e0a1109b4bb4b2f15e3ab5 155 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 81 152 6.3E-12 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 Gene3D G3DSA:3.40.140.10 128 265 1.1E-47 T 29-03-2018 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 24 263 2.7E-70 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 SUPERFAMILY SSF53927 7 262 3.61E-74 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 Gene3D G3DSA:3.10.20.10 30 86 1.4E-18 T 29-03-2018 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 PIRSF PIRSF015626 2 265 1.0E-77 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 Pfam PF02634 FdhD/NarQ family 28 262 2.3E-76 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A616_RS06800 1c958d7c4f3a3499696204d6f7330006 265 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 4 263 30.763 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A616_RS07315 d46a4eb82074e8e32e8afcefe985f4b6 316 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 316 103.018 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A616_RS07315 d46a4eb82074e8e32e8afcefe985f4b6 316 Pfam PF03186 CobD/Cbib protein 7 298 3.3E-102 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A616_RS07315 d46a4eb82074e8e32e8afcefe985f4b6 316 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 1 312 7.0E-85 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A616_RS05380 6b51eda31df1f417c9cd5a0d23a9e8c0 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 145 2.5E-17 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS05380 6b51eda31df1f417c9cd5a0d23a9e8c0 161 SUPERFAMILY SSF55961 4 152 3.4E-28 T 29-03-2018 A616_RS05380 6b51eda31df1f417c9cd5a0d23a9e8c0 161 Gene3D G3DSA:3.30.530.20 4 152 1.4E-21 T 29-03-2018 IPR023393 START-like domain A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 8 22 7.6E-7 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 70 90 7.6E-7 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 SUPERFAMILY SSF53335 1 28 5.55E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 SUPERFAMILY SSF53335 58 224 5.55E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 Gene3D G3DSA:3.40.50.150 1 286 1.3E-34 T 29-03-2018 A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 13 18 - T 29-03-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 A616_RS19405 180db90a7f63a3745d5cd36047294e42 306 Pfam PF01555 DNA methylase 12 187 1.6E-25 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A616_RS29205 1b8b5f0a3531b4884608a9dba570f556 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 3.3E-116 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A616_RS29205 1b8b5f0a3531b4884608a9dba570f556 252 Pfam PF00977 Histidine biosynthesis protein 5 233 1.3E-87 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 A616_RS29205 1b8b5f0a3531b4884608a9dba570f556 252 SUPERFAMILY SSF51366 1 251 6.52E-81 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS29205 1b8b5f0a3531b4884608a9dba570f556 252 Gene3D G3DSA:3.20.20.70 4 247 5.5E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS29205 1b8b5f0a3531b4884608a9dba570f556 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.846 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A616_RS15350 2d1242f306532910bd7498893e5eddd2 465 Pfam PF00171 Aldehyde dehydrogenase family 7 430 2.8E-94 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS15350 2d1242f306532910bd7498893e5eddd2 465 PIRSF PIRSF036492 1 465 2.9E-160 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 A616_RS15350 2d1242f306532910bd7498893e5eddd2 465 SUPERFAMILY SSF53720 6 436 7.2E-119 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS15350 2d1242f306532910bd7498893e5eddd2 465 Gene3D G3DSA:3.40.309.10 230 419 2.8E-61 T 29-03-2018 A616_RS15350 2d1242f306532910bd7498893e5eddd2 465 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 239 250 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A616_RS15350 2d1242f306532910bd7498893e5eddd2 465 Gene3D G3DSA:3.40.605.10 3 229 1.1E-62 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS26690 bcbb9d7d496366db8a99ba0a1a57358c 313 SUPERFAMILY SSF103481 213 302 3.79E-12 T 29-03-2018 A616_RS26690 bcbb9d7d496366db8a99ba0a1a57358c 313 SUPERFAMILY SSF103481 64 163 1.7E-10 T 29-03-2018 A616_RS26690 bcbb9d7d496366db8a99ba0a1a57358c 313 Pfam PF00892 EamA-like transporter family 28 157 4.6E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS26690 bcbb9d7d496366db8a99ba0a1a57358c 313 Pfam PF00892 EamA-like transporter family 170 302 2.1E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS27100 c585b066cb202092041d642274ef9b4a 311 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.036 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A616_RS27100 c585b066cb202092041d642274ef9b4a 311 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 4.6E-90 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A616_RS27100 c585b066cb202092041d642274ef9b4a 311 Pfam PF02401 LytB protein 4 284 2.9E-81 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A616_RS30260 605260b39f4dd3ee4fc8fae9da5a94e3 129 Pfam PF00085 Thioredoxin 32 119 7.6E-12 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 A616_RS30260 605260b39f4dd3ee4fc8fae9da5a94e3 129 SUPERFAMILY SSF52833 33 122 2.48E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS30260 605260b39f4dd3ee4fc8fae9da5a94e3 129 Gene3D G3DSA:3.40.30.10 28 128 6.3E-19 T 29-03-2018 A616_RS15305 61337e68d64ccbf3abe7274b6c0e64fc 156 SUPERFAMILY SSF46785 13 135 6.68E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15305 61337e68d64ccbf3abe7274b6c0e64fc 156 Gene3D G3DSA:1.10.10.10 1 155 3.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22145 aa8cd3e87630cc0712b3c27b139c6d8c 138 Pfam PF00583 Acetyltransferase (GNAT) family 48 102 8.2E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS22145 aa8cd3e87630cc0712b3c27b139c6d8c 138 Gene3D G3DSA:3.40.630.30 13 135 3.6E-9 T 29-03-2018 A616_RS22145 aa8cd3e87630cc0712b3c27b139c6d8c 138 SUPERFAMILY SSF55729 46 129 1.77E-10 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 Gene3D G3DSA:1.10.10.60 3 57 7.0E-15 T 29-03-2018 A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 Gene3D G3DSA:1.10.357.10 58 160 4.0E-7 T 29-03-2018 A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 SUPERFAMILY SSF46689 5 75 1.23E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 2.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 7.9E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS19135 c06d8c52091bf3b93811d5929319fae1 168 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS19535 ed94fb3f9967d44cabf65f1eb2df5bd8 147 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 12 117 1.6E-23 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA A616_RS19535 ed94fb3f9967d44cabf65f1eb2df5bd8 147 SUPERFAMILY SSF158622 7 126 4.06E-34 T 29-03-2018 IPR023378 YheA/YmcA-like domain A616_RS19535 ed94fb3f9967d44cabf65f1eb2df5bd8 147 Gene3D G3DSA:1.20.1500.10 11 119 3.8E-30 T 29-03-2018 IPR023378 YheA/YmcA-like domain A616_RS19535 ed94fb3f9967d44cabf65f1eb2df5bd8 147 PIRSF PIRSF021287 4 126 1.9E-39 T 29-03-2018 IPR016783 Biofilm formation YmcA A616_RS21700 eb1f284e08c63f01478b994cb408a5c7 275 Gene3D G3DSA:3.40.1190.20 1 274 5.7E-54 T 29-03-2018 IPR029056 Ribokinase-like A616_RS21700 eb1f284e08c63f01478b994cb408a5c7 275 SUPERFAMILY SSF53613 3 266 4.37E-73 T 29-03-2018 IPR029056 Ribokinase-like A616_RS21700 eb1f284e08c63f01478b994cb408a5c7 275 Pfam PF08543 Phosphomethylpyrimidine kinase 13 261 4.5E-85 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A616_RS21700 eb1f284e08c63f01478b994cb408a5c7 275 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 1.6E-83 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 SUPERFAMILY SSF118215 6 402 1.14E-124 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 1.3E-121 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 2.1E-38 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 Gene3D G3DSA:1.10.3860.10 1 408 9.7E-128 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS08915 8f230bc61405037a45585aacdcce1b2a 424 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 SUPERFAMILY SSF52540 1 270 1.09E-126 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 Hamap MF_01227 CTP synthase [pyrG]. 2 531 52.662 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 SUPERFAMILY SSF52317 290 529 1.75E-82 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 Gene3D G3DSA:3.40.50.300 1 286 1.1E-135 T 29-03-2018 A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 2.7E-264 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 Pfam PF00117 Glutamine amidotransferase class-I 302 527 3.3E-57 T 29-03-2018 IPR017926 Glutamine amidotransferase A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 Pfam PF06418 CTP synthase N-terminus 3 267 8.7E-131 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A616_RS30115 3be8266f6c652b6aa3492892bdd70c3b 531 Gene3D G3DSA:3.40.50.880 287 531 1.6E-75 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS06010 d59ecde60af0094a320d2462a93bfd8f 124 Pfam PF11023 Zinc-ribbon containing domain 7 115 2.6E-23 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A616_RS06010 d59ecde60af0094a320d2462a93bfd8f 124 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 8 115 1.0E-15 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 18 383 3.0E-176 T 29-03-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 Pfam PF00190 Cupin 234 367 1.8E-22 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 Pfam PF00190 Cupin 64 190 1.6E-18 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 Gene3D G3DSA:2.60.120.10 5 212 1.8E-44 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 Gene3D G3DSA:2.60.120.10 215 386 1.1E-36 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 SUPERFAMILY SSF51182 20 382 1.39E-104 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 SMART SM00835 54 196 5.6E-19 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 SMART SM00835 232 373 1.9E-28 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 A616_RS27845 539f7ff6fa5b9fe0f55edf5fa8f93ac0 392 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 79 166 6.0E-4 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A616_RS03640 926970981df6127d9fd47e3038bb7e2c 348 Gene3D G3DSA:1.10.3470.10 15 337 3.2E-52 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS03640 926970981df6127d9fd47e3038bb7e2c 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 332 1.4E-43 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS13820 dd6db3f68833dab96831688021cd072a 222 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 206 1.6E-47 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A616_RS13820 dd6db3f68833dab96831688021cd072a 222 Gene3D G3DSA:3.20.20.70 1 213 2.8E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS13820 dd6db3f68833dab96831688021cd072a 222 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 211 37.895 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A616_RS13820 dd6db3f68833dab96831688021cd072a 222 SUPERFAMILY SSF51366 3 209 5.49E-50 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS15055 cdc057c58e3628c579f4aff221f21f65 449 Gene3D G3DSA:3.20.20.30 1 447 3.2E-100 T 29-03-2018 A616_RS15055 cdc057c58e3628c579f4aff221f21f65 449 SUPERFAMILY SSF51679 3 434 5.36E-131 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS15055 cdc057c58e3628c579f4aff221f21f65 449 PIRSF PIRSF000337 1 443 1.1E-157 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A616_RS15055 cdc057c58e3628c579f4aff221f21f65 449 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 8 428 1.2E-167 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A616_RS15055 cdc057c58e3628c579f4aff221f21f65 449 Pfam PF00296 Luciferase-like monooxygenase 17 384 6.1E-60 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS22885 5b65eaa32921c5214ac1a1d1083cbc7a 415 Gene3D G3DSA:1.20.1250.20 2 190 4.1E-33 T 29-03-2018 A616_RS22885 5b65eaa32921c5214ac1a1d1083cbc7a 415 SUPERFAMILY SSF103473 10 397 4.58E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS22885 5b65eaa32921c5214ac1a1d1083cbc7a 415 Gene3D G3DSA:1.20.1250.20 197 411 3.4E-26 T 29-03-2018 A616_RS22885 5b65eaa32921c5214ac1a1d1083cbc7a 415 Pfam PF07690 Major Facilitator Superfamily 17 275 1.7E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS28790 1048becc64644a375e8964c2a4d534bf 492 Gene3D G3DSA:3.40.1360.10 288 487 1.3E-19 T 29-03-2018 A616_RS28790 1048becc64644a375e8964c2a4d534bf 492 SUPERFAMILY SSF56726 320 487 1.26E-13 T 29-03-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A616_RS28790 1048becc64644a375e8964c2a4d534bf 492 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 317 469 1.3E-7 T 29-03-2018 IPR024534 Domain of unknown function DUF2220 A616_RS18340 c8e5657b670bf9928d0efaa54dc42ce5 112 Pfam PF14189 Domain of unknown function (DUF4312) 6 87 3.2E-30 T 29-03-2018 IPR020037 Protein of unknown function DUF4312 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 141 2.4E-32 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 SUPERFAMILY SSF55347 150 314 6.54E-58 T 29-03-2018 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 346 5.0E-138 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 340 43.485 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 317 2.3E-25 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 SMART SM00859 3 142 1.8E-50 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 Gene3D G3DSA:3.40.50.720 1 159 2.9E-38 T 29-03-2018 A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 SUPERFAMILY SSF51735 2 177 4.3E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS29370 99456f3aca78f48ae4983489e5facc7c 346 Gene3D G3DSA:3.30.360.10 160 314 5.8E-63 T 29-03-2018 A616_RS31760 ed73e3dc1977b92d659c4b58467f6102 563 Gene3D G3DSA:1.50.10.10 172 563 1.2E-66 T 29-03-2018 A616_RS31760 ed73e3dc1977b92d659c4b58467f6102 563 SUPERFAMILY SSF48208 142 563 1.51E-87 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A616_RS31760 ed73e3dc1977b92d659c4b58467f6102 563 Pfam PF01204 Trehalase 375 528 1.2E-9 T 29-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 SMART SM00829 10 322 4.0E-54 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 Gene3D G3DSA:3.40.50.720 137 257 9.6E-28 T 29-03-2018 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 Gene3D G3DSA:3.90.180.10 258 326 8.9E-7 T 29-03-2018 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 SUPERFAMILY SSF51735 111 269 1.87E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 Gene3D G3DSA:3.90.180.10 1 136 3.9E-44 T 29-03-2018 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 SUPERFAMILY SSF50129 1 144 9.28E-38 T 29-03-2018 IPR011032 GroES-like A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 7.7E-12 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 Pfam PF00107 Zinc-binding dehydrogenase 150 272 8.4E-30 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A616_RS08960 a82b094ddd42cdf00f1e3f1a0cd8e04e 326 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A616_RS11890 139779a6c3804274f04f1d1dadcb763a 109 SMART SM00530 5 61 3.2E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS11890 139779a6c3804274f04f1d1dadcb763a 109 SUPERFAMILY SSF47406 73 106 6.02E-13 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A616_RS11890 139779a6c3804274f04f1d1dadcb763a 109 Pfam PF01381 Helix-turn-helix 6 60 6.5E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS11890 139779a6c3804274f04f1d1dadcb763a 109 Gene3D G3DSA:1.10.260.40 1 109 2.1E-27 T 29-03-2018 A616_RS11890 139779a6c3804274f04f1d1dadcb763a 109 SUPERFAMILY SSF47413 1 64 1.69E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS11890 139779a6c3804274f04f1d1dadcb763a 109 Pfam PF08671 Anti-repressor SinI 74 100 2.7E-14 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A616_RS07270 653b1bd4074f32721c76050b7d2b8bcd 149 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 45 111 8.0E-6 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS07270 653b1bd4074f32721c76050b7d2b8bcd 149 Pfam PF04284 Protein of unknown function (DUF441) 6 143 1.6E-31 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS07270 653b1bd4074f32721c76050b7d2b8bcd 149 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 2 147 14.811 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 Gene3D G3DSA:3.40.470.10 1 226 6.0E-101 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 SMART SM00986 50 210 3.4E-38 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 40.597 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 SUPERFAMILY SSF52141 4 222 1.41E-93 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 SMART SM00987 50 210 3.4E-38 T 29-03-2018 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 213 2.4E-84 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS30365 664c91176cf42c2d8c90f8365f635d84 229 Pfam PF03167 Uracil DNA glycosylase superfamily 55 209 1.6E-29 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A616_RS03030 a0756de56afd1dce609321cf49a85634 260 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 183 1.7E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS03030 a0756de56afd1dce609321cf49a85634 260 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 191 1.3E-15 T 29-03-2018 IPR023214 HAD-like domain A616_RS03030 a0756de56afd1dce609321cf49a85634 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 5.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS03030 a0756de56afd1dce609321cf49a85634 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 5.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS03030 a0756de56afd1dce609321cf49a85634 260 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 5.7E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS03030 a0756de56afd1dce609321cf49a85634 260 SUPERFAMILY SSF56784 4 194 8.02E-28 T 29-03-2018 IPR023214 HAD-like domain A616_RS03030 a0756de56afd1dce609321cf49a85634 260 Gene3D G3DSA:3.40.50.1000 1 205 1.2E-23 T 29-03-2018 IPR023214 HAD-like domain A616_RS30390 eee698da104542941891bc9df6ccd8fc 402 SUPERFAMILY SSF53383 32 392 1.73E-128 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS30390 eee698da104542941891bc9df6ccd8fc 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 391 3.6E-150 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS30390 eee698da104542941891bc9df6ccd8fc 402 Gene3D G3DSA:3.40.640.10 6 259 1.3E-64 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS30390 eee698da104542941891bc9df6ccd8fc 402 Gene3D G3DSA:3.90.1150.10 261 401 1.6E-55 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS30390 eee698da104542941891bc9df6ccd8fc 402 PIRSF PIRSF001434 1 395 3.2E-150 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS30390 eee698da104542941891bc9df6ccd8fc 402 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A616_RS22370 6a4d878a45532d0f2825688d0d4db83f 148 Gene3D G3DSA:3.40.630.30 44 144 1.2E-15 T 29-03-2018 A616_RS22370 6a4d878a45532d0f2825688d0d4db83f 148 Pfam PF00583 Acetyltransferase (GNAT) family 41 131 1.0E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS22370 6a4d878a45532d0f2825688d0d4db83f 148 SUPERFAMILY SSF55729 2 140 4.87E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS22370 6a4d878a45532d0f2825688d0d4db83f 148 Gene3D G3DSA:1.10.287.900 1 34 3.3E-12 T 29-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 A616_RS02145 36a499595a395d59fb44b027b6152a33 223 Gene3D G3DSA:2.20.25.10 184 222 9.0E-13 T 29-03-2018 A616_RS02145 36a499595a395d59fb44b027b6152a33 223 Gene3D G3DSA:2.40.50.40 114 182 1.5E-17 T 29-03-2018 A616_RS02145 36a499595a395d59fb44b027b6152a33 223 SMART SM00850 123 222 2.0E-29 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS02145 36a499595a395d59fb44b027b6152a33 223 Pfam PF04397 LytTr DNA-binding domain 125 221 3.8E-25 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS00590 b94805475116c8446b3cec597274ac8d 123 Pfam PF06156 Initiation control protein YabA 2 115 1.2E-35 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 A616_RS00590 b94805475116c8446b3cec597274ac8d 123 Hamap MF_01159 Initiation-control protein YabA. 1 119 22.306 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 A616_RS00590 b94805475116c8446b3cec597274ac8d 123 Gene3D G3DSA:1.20.5.340 3 91 1.4E-4 T 29-03-2018 A616_RS00590 b94805475116c8446b3cec597274ac8d 123 PIRSF PIRSF021439 1 120 4.8E-37 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 A616_RS06110 65eeecfe1cf54f4f388d011c557c3268 146 Hamap MF_00042 Ribonuclease H [rnhA]. 3 146 28.013 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 A616_RS06110 65eeecfe1cf54f4f388d011c557c3268 146 PIRSF PIRSF037839 2 133 2.0E-7 T 29-03-2018 IPR017290 Ribonuclease H, Bacteroides-type GO:0004523 A616_RS06110 65eeecfe1cf54f4f388d011c557c3268 146 Gene3D G3DSA:3.30.420.10 2 146 6.2E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS06110 65eeecfe1cf54f4f388d011c557c3268 146 Pfam PF00075 RNase H 5 143 5.6E-42 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A616_RS06110 65eeecfe1cf54f4f388d011c557c3268 146 SUPERFAMILY SSF53098 6 145 1.19E-54 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS07580 2cdb55aa9efb15087ec4b485a3d3b2f8 137 Pfam PF07080 Protein of unknown function (DUF1348) 7 137 2.6E-62 T 29-03-2018 IPR009783 Protein of unknown function DUF1348 A616_RS07580 2cdb55aa9efb15087ec4b485a3d3b2f8 137 SUPERFAMILY SSF54427 3 136 1.35E-64 T 29-03-2018 IPR032710 NTF2-like domain A616_RS07580 2cdb55aa9efb15087ec4b485a3d3b2f8 137 Gene3D G3DSA:3.10.450.50 10 137 4.4E-59 T 29-03-2018 A616_RS18950 3c57be697eed92faf1c5cc9543527c97 309 SUPERFAMILY SSF51658 24 293 4.04E-16 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS18950 3c57be697eed92faf1c5cc9543527c97 309 Pfam PF01261 Xylose isomerase-like TIM barrel 30 239 1.6E-7 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS18950 3c57be697eed92faf1c5cc9543527c97 309 Gene3D G3DSA:3.20.20.150 4 306 1.9E-25 T 29-03-2018 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 SUPERFAMILY SSF53474 5 275 2.36E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 2.3E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 2.3E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 2.3E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 PRINTS PR00412 Epoxide hydrolase signature 250 272 4.0E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 PRINTS PR00412 Epoxide hydrolase signature 44 59 4.0E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 PRINTS PR00412 Epoxide hydrolase signature 102 115 4.0E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 Gene3D G3DSA:3.40.50.1820 3 282 2.0E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS23880 a19d7f8d99952ca159bf2a6a84cc52a0 283 Pfam PF00561 alpha/beta hydrolase fold 20 120 2.9E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS31290 0e3da66cf3c057af28470c050f910181 205 Pfam PF04203 Sortase family 75 196 2.3E-26 T 29-03-2018 IPR005754 Sortase family A616_RS31290 0e3da66cf3c057af28470c050f910181 205 Gene3D G3DSA:2.40.260.10 19 205 8.7E-35 T 29-03-2018 IPR023365 Sortase domain A616_RS31290 0e3da66cf3c057af28470c050f910181 205 SUPERFAMILY SSF63817 66 198 1.27E-31 T 29-03-2018 IPR023365 Sortase domain A616_RS31290 0e3da66cf3c057af28470c050f910181 205 TIGRFAM TIGR01076 sortase_fam: sortase 73 196 2.4E-20 T 29-03-2018 IPR005754 Sortase family A616_RS15995 4618bbedee2f772d4ec556ea608b8a48 294 Pfam PF04909 Amidohydrolase 68 281 1.0E-41 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS15995 4618bbedee2f772d4ec556ea608b8a48 294 Gene3D G3DSA:3.20.20.140 7 293 1.1E-41 T 29-03-2018 A616_RS15995 4618bbedee2f772d4ec556ea608b8a48 294 SUPERFAMILY SSF51556 43 282 2.62E-52 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS10485 b6acd8386233f809bde37ab8d252de1a 195 Gene3D G3DSA:3.90.950.10 1 190 8.6E-71 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A616_RS10485 b6acd8386233f809bde37ab8d252de1a 195 Pfam PF02545 Maf-like protein 8 189 5.0E-57 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 A616_RS10485 b6acd8386233f809bde37ab8d252de1a 195 PIRSF PIRSF006305 1 194 7.6E-55 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 A616_RS10485 b6acd8386233f809bde37ab8d252de1a 195 Hamap MF_00528 Septum formation protein Maf [maf]. 7 194 32.878 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 A616_RS10485 b6acd8386233f809bde37ab8d252de1a 195 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 187 4.1E-56 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 A616_RS10485 b6acd8386233f809bde37ab8d252de1a 195 SUPERFAMILY SSF52972 5 189 9.16E-62 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A616_RS05940 ed96a090189de2da3367d338232ccf35 264 Pfam PF06182 ABC-2 family transporter protein 32 263 2.7E-21 T 29-03-2018 IPR010390 Protein of unknown function DUF990 A616_RS06140 8f9bb1734c0b3f199082582e89b74691 241 Gene3D G3DSA:3.40.50.1000 1 233 5.2E-24 T 29-03-2018 IPR023214 HAD-like domain A616_RS06140 8f9bb1734c0b3f199082582e89b74691 241 SUPERFAMILY SSF56784 4 232 2.44E-32 T 29-03-2018 IPR023214 HAD-like domain A616_RS06140 8f9bb1734c0b3f199082582e89b74691 241 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 118 197 7.1E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS06140 8f9bb1734c0b3f199082582e89b74691 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 205 3.8E-16 T 29-03-2018 IPR023214 HAD-like domain A616_RS01525 d17d3f395afc627230b63680b458ea60 122 Gene3D G3DSA:4.10.910.10 87 122 4.4E-27 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 3.1E-55 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 Gene3D G3DSA:1.10.8.50 1 67 7.0E-27 T 29-03-2018 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 29.168 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 PIRSF PIRSF002134 1 122 1.1E-43 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 Gene3D G3DSA:4.10.910.10 68 86 4.0E-18 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 7.9E-35 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01525 d17d3f395afc627230b63680b458ea60 122 SUPERFAMILY SSF46946 2 121 4.71E-47 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A616_RS06725 acc57bad6a7b21a26df674b9616b62cb 164 Gene3D G3DSA:1.20.120.450 3 156 4.4E-20 T 29-03-2018 A616_RS06725 acc57bad6a7b21a26df674b9616b62cb 164 Pfam PF12867 DinB superfamily 26 147 5.1E-13 T 29-03-2018 IPR024775 DinB-like domain A616_RS06725 acc57bad6a7b21a26df674b9616b62cb 164 SUPERFAMILY SSF109854 1 158 1.47E-17 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS21440 f0dd6c072b71a1058113abef0775a6f0 365 SUPERFAMILY SSF53335 15 363 2.76E-89 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS21440 f0dd6c072b71a1058113abef0775a6f0 365 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 64 299 4.3E-51 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 A616_RS21440 f0dd6c072b71a1058113abef0775a6f0 365 Gene3D G3DSA:3.40.50.150 30 293 1.2E-4 T 29-03-2018 A616_RS31425 3b144e232b9f639da67e377e1366d74e 277 Pfam PF02673 Bacitracin resistance protein BacA 9 271 7.7E-83 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A616_RS31425 3b144e232b9f639da67e377e1366d74e 277 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 269 5.0E-94 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A616_RS31425 3b144e232b9f639da67e377e1366d74e 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 276 17.775 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A616_RS32115 c325103522b92f2535881a8154a00d7f 460 Pfam PF07435 YycH protein 7 446 2.0E-52 T 29-03-2018 IPR009996 Regulatory protein YycH A616_RS14900 d6e7577b64c4cee0d73ec78d31065dad 98 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 1 83 4.4E-15 T 29-03-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family A616_RS05555 e5577d420fe64fff0f339ad37c7c4410 269 Gene3D G3DSA:1.10.10.10 2 101 6.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05555 e5577d420fe64fff0f339ad37c7c4410 269 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 7.4E-23 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal A616_RS05555 e5577d420fe64fff0f339ad37c7c4410 269 SUPERFAMILY SSF46785 6 111 1.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18480 432aa54e7bbf4a9dc08376f2d4004f75 322 SUPERFAMILY SSF51735 2 321 3.03E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS18480 432aa54e7bbf4a9dc08376f2d4004f75 322 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 15 314 6.2E-27 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS18480 432aa54e7bbf4a9dc08376f2d4004f75 322 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 2 322 5.2E-111 T 29-03-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB A616_RS18480 432aa54e7bbf4a9dc08376f2d4004f75 322 Gene3D G3DSA:3.40.50.720 142 295 3.6E-13 T 29-03-2018 A616_RS18480 432aa54e7bbf4a9dc08376f2d4004f75 322 PIRSF PIRSF001439 1 322 1.3E-51 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 A616_RS18480 432aa54e7bbf4a9dc08376f2d4004f75 322 Gene3D G3DSA:3.30.1780.10 1 141 2.6E-31 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 A616_RS23230 2dccef5a820f03f6ca38bd74f93ca951 211 Gene3D G3DSA:3.10.350.10 157 209 2.7E-5 T 29-03-2018 A616_RS23160 a1be6dd1d101a3940f6ce73fdce5134c 107 Pfam PF13031 Protein of unknown function (DUF3892) 38 105 1.4E-15 T 29-03-2018 IPR024997 Protein of unknown function DUF3892 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 500 5.9E-261 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 365 2.3E-76 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 372 495 2.4E-49 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 93 5.8E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Gene3D G3DSA:3.40.50.300 84 365 4.6E-122 T 29-03-2018 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 SUPERFAMILY SSF47917 373 499 3.92E-50 T 29-03-2018 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 356 365 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Gene3D G3DSA:1.20.150.20 374 499 2.9E-53 T 29-03-2018 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 SUPERFAMILY SSF50615 11 95 1.26E-30 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Gene3D G3DSA:2.40.30.20 4 83 2.9E-39 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 PIRSF PIRSF039088 2 502 8.5E-259 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 500 52.449 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A616_RS29910 a491f09be3d2b1f862745ca38840b518 503 SUPERFAMILY SSF52540 96 371 2.1E-101 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 Pfam PF09369 Domain of unknown function (DUF1998) 655 734 1.2E-21 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 SUPERFAMILY SSF52540 41 241 3.62E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 SMART SM00490 311 394 3.6E-13 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 SMART SM00487 56 260 3.8E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 SUPERFAMILY SSF52540 74 129 1.98E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 SUPERFAMILY SSF52540 314 451 1.98E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 Gene3D G3DSA:3.40.50.300 33 253 1.2E-33 T 29-03-2018 A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 Pfam PF00270 DEAD/DEAH box helicase 63 233 8.6E-28 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 Pfam PF00271 Helicase conserved C-terminal domain 292 393 6.0E-12 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS27770 16bd9d563a2761837e9ac8d65d7b55f2 760 Gene3D G3DSA:3.40.50.300 271 428 2.8E-18 T 29-03-2018 A616_RS21560 f2915e2831864f63e7c905551c6046c4 168 Pfam PF14584 Protein of unknown function (DUF4446) 14 162 6.6E-50 T 29-03-2018 IPR027981 Protein of unknown function DUF4446 A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 Pfam PF00905 Penicillin binding protein transpeptidase domain 329 597 3.4E-29 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 74 602 4.8E-181 T 29-03-2018 A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 Gene3D G3DSA:1.10.3810.10 54 254 3.8E-76 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 Pfam PF00912 Transglycosylase 62 237 1.5E-63 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 Gene3D G3DSA:3.40.710.10 256 655 5.7E-114 T 29-03-2018 A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 SUPERFAMILY SSF56601 219 241 7.45E-120 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 SUPERFAMILY SSF56601 271 655 7.45E-120 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS30225 7c29e3cd4630ea97865b1946feb7b6c9 683 SUPERFAMILY SSF53955 51 263 9.28E-76 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS19065 cc62951a66b84dbd1b876b58d6d57f29 65 SUPERFAMILY SSF158221 3 42 2.48E-13 T 29-03-2018 A616_RS19065 cc62951a66b84dbd1b876b58d6d57f29 65 Hamap MF_01103 UPF0291 protein . 2 62 14.404 T 29-03-2018 IPR009242 Protein of unknown function DUF896 A616_RS19065 cc62951a66b84dbd1b876b58d6d57f29 65 Gene3D G3DSA:1.10.287.540 4 56 3.3E-21 T 29-03-2018 A616_RS19065 cc62951a66b84dbd1b876b58d6d57f29 65 Pfam PF05979 Bacterial protein of unknown function (DUF896) 6 56 1.4E-17 T 29-03-2018 IPR009242 Protein of unknown function DUF896 A616_RS25720 98a1e3c184e9d0368f570e39e355efba 101 SUPERFAMILY SSF109604 28 86 1.0E-4 T 29-03-2018 A616_RS25720 98a1e3c184e9d0368f570e39e355efba 101 Gene3D G3DSA:1.10.3210.10 55 98 0.013 T 29-03-2018 A616_RS25720 98a1e3c184e9d0368f570e39e355efba 101 Gene3D G3DSA:1.10.3210.10 3 50 0.22 T 29-03-2018 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 Gene3D G3DSA:3.90.230.10 1 248 1.3E-84 T 29-03-2018 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 Pfam PF00557 Metallopeptidase family M24 12 239 2.7E-55 T 29-03-2018 IPR000994 Peptidase M24 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 3.1E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.1E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.1E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 3.1E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 SUPERFAMILY SSF55920 1 247 4.06E-91 T 29-03-2018 IPR000994 Peptidase M24 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 3.6E-100 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01510 80c8171eb90c50fc014c43a9b73b489c 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 42.544 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 SUPERFAMILY SSF46785 5 85 4.22E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 SMART SM00345 16 75 4.0E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 SUPERFAMILY SSF53383 122 476 5.77E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 Pfam PF00155 Aminotransferase class I and II 156 445 2.0E-14 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 Gene3D G3DSA:1.10.10.10 1 88 1.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 Gene3D G3DSA:3.90.1150.10 381 479 8.7E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 75 4.0E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A616_RS06840 fef5f980774a2eac1e88979ffeef6aea 486 Gene3D G3DSA:3.40.640.10 141 380 1.1E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 306 3.7E-136 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 SUPERFAMILY SSF53686 1 307 1.27E-103 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 294 2.8E-69 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 Gene3D G3DSA:3.40.50.1100 140 309 1.3E-58 T 29-03-2018 A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 306 3.9E-142 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A616_RS01110 fdea0f57d7325cc9ad0b036677273222 310 Gene3D G3DSA:3.40.50.1100 41 139 2.3E-39 T 29-03-2018 A616_RS12180 3ae11fda0e78b5775c0a0f47804bd77a 115 Pfam PF01476 LysM domain 3 46 4.8E-15 T 29-03-2018 IPR018392 LysM domain A616_RS12180 3ae11fda0e78b5775c0a0f47804bd77a 115 SMART SM00257 2 46 8.2E-15 T 29-03-2018 IPR018392 LysM domain A616_RS12180 3ae11fda0e78b5775c0a0f47804bd77a 115 Gene3D G3DSA:3.10.350.10 1 54 1.3E-17 T 29-03-2018 A616_RS12180 3ae11fda0e78b5775c0a0f47804bd77a 115 SUPERFAMILY SSF54106 2 46 1.57E-13 T 29-03-2018 IPR018392 LysM domain A616_RS12180 3ae11fda0e78b5775c0a0f47804bd77a 115 Gene3D G3DSA:3.90.20.10 55 100 5.9E-7 T 29-03-2018 A616_RS18010 a60ec27c26db57950fc250077dbca72c 127 SMART SM01298 13 124 1.0E-64 T 29-03-2018 IPR014916 Kinase associated protein B A616_RS18010 a60ec27c26db57950fc250077dbca72c 127 Pfam PF08810 Kinase associated protein B 14 121 7.8E-41 T 29-03-2018 IPR014916 Kinase associated protein B A616_RS18010 a60ec27c26db57950fc250077dbca72c 127 SUPERFAMILY SSF141251 3 121 6.54E-36 T 29-03-2018 A616_RS14905 6058d1df23bf396f564491b4fd83906e 647 Gene3D G3DSA:3.40.50.720 163 333 1.1E-7 T 29-03-2018 A616_RS14905 6058d1df23bf396f564491b4fd83906e 647 TIGRFAM TIGR03693 ocin_ThiF_like: putative thiazole-containing bacteriocin maturation protein 1 644 5.5E-178 T 29-03-2018 IPR022368 Putative thiazole-containing bacteriocin maturation protein A616_RS24920 e80d889ea8f372a2cecab379a5f042ce 185 Pfam PF00881 Nitroreductase family 7 165 4.2E-23 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS24920 e80d889ea8f372a2cecab379a5f042ce 185 SUPERFAMILY SSF55469 1 184 1.15E-38 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS24920 e80d889ea8f372a2cecab379a5f042ce 185 Gene3D G3DSA:3.40.109.10 1 185 1.2E-33 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS21805 30a24e156e8e522317dae2bc485bfecd 258 Pfam PF00005 ABC transporter 17 165 1.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS21805 30a24e156e8e522317dae2bc485bfecd 258 Gene3D G3DSA:3.40.50.300 1 238 1.2E-60 T 29-03-2018 A616_RS21805 30a24e156e8e522317dae2bc485bfecd 258 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS21805 30a24e156e8e522317dae2bc485bfecd 258 SUPERFAMILY SSF52540 2 233 1.67E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21805 30a24e156e8e522317dae2bc485bfecd 258 SMART SM00382 26 223 7.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS04380 74a0585bae5b315542489a84a69c799c 261 Pfam PF13649 Methyltransferase domain 63 151 4.1E-8 T 29-03-2018 A616_RS04380 74a0585bae5b315542489a84a69c799c 261 Gene3D G3DSA:3.40.50.150 2 193 3.3E-18 T 29-03-2018 A616_RS04380 74a0585bae5b315542489a84a69c799c 261 SUPERFAMILY SSF53335 6 244 1.65E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 2.0E-19 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 2.0E-19 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 2.0E-19 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 7 15 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 PIRSF PIRSF001220 1 323 5.3E-99 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 SUPERFAMILY SSF53774 3 323 3.4E-103 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 Gene3D G3DSA:3.40.50.40 207 323 4.7E-34 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 Gene3D G3DSA:3.40.50.1170 1 206 3.7E-56 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 Pfam PF00710 Asparaginase, N-terminal 4 191 2.0E-61 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 81 91 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 SMART SM00870 4 318 3.4E-133 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A616_RS13605 0facb88a9f4758ce77ddbe09900980a5 323 PIRSF PIRSF500176 1 323 2.7E-92 T 29-03-2018 A616_RS04325 191076b5848a6ba40cf1e3b8a256331b 440 SUPERFAMILY SSF63825 234 283 2.25E-7 T 29-03-2018 A616_RS04325 191076b5848a6ba40cf1e3b8a256331b 440 SUPERFAMILY SSF63825 154 206 2.25E-7 T 29-03-2018 A616_RS04325 191076b5848a6ba40cf1e3b8a256331b 440 Gene3D G3DSA:2.130.10.10 218 437 0.0044 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A616_RS04325 191076b5848a6ba40cf1e3b8a256331b 440 Gene3D G3DSA:2.130.10.10 72 217 0.019 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A616_RS04325 191076b5848a6ba40cf1e3b8a256331b 440 Pfam PF13449 Esterase-like activity of phytase 57 410 6.0E-63 T 29-03-2018 IPR027372 Phytase-like domain A616_RS01595 22540d331acafe490b099b4ee2567074 256 SUPERFAMILY SSF88713 48 245 2.67E-59 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS01595 22540d331acafe490b099b4ee2567074 256 Pfam PF01522 Polysaccharide deacetylase 55 177 5.5E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS01595 22540d331acafe490b099b4ee2567074 256 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 54 245 3.1E-82 T 29-03-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB A616_RS01595 22540d331acafe490b099b4ee2567074 256 Gene3D G3DSA:3.20.20.370 31 253 2.0E-55 T 29-03-2018 A616_RS07220 e25db17c7b8d6201c893baf691e4d299 268 Pfam PF12679 ABC-2 family transporter protein 7 266 2.3E-12 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS14020 2df2e6eff115fd6aadcfdf79695f43ef 227 Gene3D G3DSA:1.10.10.10 4 122 4.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14020 2df2e6eff115fd6aadcfdf79695f43ef 227 Gene3D G3DSA:1.10.10.630 133 208 2.6E-21 T 29-03-2018 IPR034829 DnaD-like domain A616_RS14020 2df2e6eff115fd6aadcfdf79695f43ef 227 Pfam PF07261 Replication initiation and membrane attachment 140 210 7.2E-24 T 29-03-2018 IPR006343 DnaD domain A616_RS14020 2df2e6eff115fd6aadcfdf79695f43ef 227 SUPERFAMILY SSF158499 138 203 2.62E-17 T 29-03-2018 IPR006343 DnaD domain A616_RS14020 2df2e6eff115fd6aadcfdf79695f43ef 227 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 137 208 2.0E-21 T 29-03-2018 IPR006343 DnaD domain A616_RS14020 2df2e6eff115fd6aadcfdf79695f43ef 227 SUPERFAMILY SSF46785 4 114 9.35E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24170 6968df0d68af80e05f1a58291cdbd67a 490 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 489 9.8E-222 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 A616_RS24170 6968df0d68af80e05f1a58291cdbd67a 490 Pfam PF00474 Sodium:solute symporter family 35 433 2.2E-109 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS24170 6968df0d68af80e05f1a58291cdbd67a 490 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 433 4.0E-98 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS24170 6968df0d68af80e05f1a58291cdbd67a 490 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 415 435 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A616_RS04095 438d00b196fd56097e699f8ec2c6a61a 134 SUPERFAMILY SSF88659 45 110 8.37E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS04095 438d00b196fd56097e699f8ec2c6a61a 134 Gene3D G3DSA:1.10.10.10 42 115 4.6E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12080 754e56857383662b545d1fb3f411b3ae 98 SUPERFAMILY SSF47789 43 96 4.05E-12 T 29-03-2018 A616_RS12080 754e56857383662b545d1fb3f411b3ae 98 Gene3D G3DSA:1.10.150.20 40 98 1.0E-14 T 29-03-2018 A616_RS12080 754e56857383662b545d1fb3f411b3ae 98 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 43 90 2.5E-6 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 SUPERFAMILY SSF48452 258 394 2.47E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 Gene3D G3DSA:1.10.287.110 1 115 6.7E-8 T 29-03-2018 IPR001623 DnaJ domain A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 Pfam PF14559 Tetratricopeptide repeat 335 393 3.9E-7 T 29-03-2018 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 SMART SM00028 290 323 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 SMART SM00028 358 391 0.0069 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 SMART SM00028 324 357 0.24 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 SUPERFAMILY SSF46565 3 47 1.7E-7 T 29-03-2018 IPR001623 DnaJ domain A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 Gene3D G3DSA:1.25.40.10 371 428 1.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 Gene3D G3DSA:1.25.40.10 340 370 5.5E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS10900 444bb36f37a4dbf99531c80525f65cd7 664 Gene3D G3DSA:1.25.40.10 253 339 3.5E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS05570 942ec918b60f890772faa3d566bbdcdb 193 Pfam PF01965 DJ-1/PfpI family 2 169 6.7E-30 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS05570 942ec918b60f890772faa3d566bbdcdb 193 SUPERFAMILY SSF52317 2 171 8.11E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS05570 942ec918b60f890772faa3d566bbdcdb 193 Gene3D G3DSA:3.40.50.880 1 190 3.1E-25 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS13650 c4ac121ae473c06efb0e3131c033a54d 350 Pfam PF01070 FMN-dependent dehydrogenase 167 321 1.5E-15 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 A616_RS13650 c4ac121ae473c06efb0e3131c033a54d 350 PIRSF PIRSF003314 1 340 4.9E-115 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A616_RS13650 c4ac121ae473c06efb0e3131c033a54d 350 Gene3D G3DSA:3.20.20.70 4 343 1.2E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS13650 c4ac121ae473c06efb0e3131c033a54d 350 SUPERFAMILY SSF51395 24 340 6.28E-76 T 29-03-2018 A616_RS13650 c4ac121ae473c06efb0e3131c033a54d 350 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 4 331 36.696 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A616_RS13650 c4ac121ae473c06efb0e3131c033a54d 350 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 7 330 7.9E-112 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A616_RS01425 081ffbae544e6227aa686070f935476c 110 Gene3D G3DSA:3.90.470.10 1 110 1.1E-44 T 29-03-2018 A616_RS01425 081ffbae544e6227aa686070f935476c 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 7.4E-51 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01425 081ffbae544e6227aa686070f935476c 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.35 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01425 081ffbae544e6227aa686070f935476c 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 4.6E-38 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A616_RS01425 081ffbae544e6227aa686070f935476c 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01425 081ffbae544e6227aa686070f935476c 110 SUPERFAMILY SSF54843 1 110 1.31E-44 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 Pfam PF07690 Major Facilitator Superfamily 8 353 3.8E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 Gene3D G3DSA:1.20.1250.20 207 398 6.6E-18 T 29-03-2018 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 SUPERFAMILY SSF103473 4 389 2.22E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 Gene3D G3DSA:1.20.1250.20 1 202 1.1E-27 T 29-03-2018 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 PRINTS PR01035 Tetracycline resistance protein signature 14 30 3.1E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 PRINTS PR01035 Tetracycline resistance protein signature 169 189 3.1E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 PRINTS PR01035 Tetracycline resistance protein signature 141 163 3.1E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS17640 6f40778a5b40c510c7070e4a2d647d9a 399 PRINTS PR01035 Tetracycline resistance protein signature 337 360 3.1E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS15545 11133e7c1075dc02ec7856f9ef9b502a 135 Pfam PF01575 MaoC like domain 18 114 1.5E-18 T 29-03-2018 IPR002539 MaoC-like domain A616_RS15545 11133e7c1075dc02ec7856f9ef9b502a 135 Gene3D G3DSA:3.10.129.10 2 133 3.5E-26 T 29-03-2018 A616_RS15545 11133e7c1075dc02ec7856f9ef9b502a 135 SUPERFAMILY SSF54637 3 135 5.57E-24 T 29-03-2018 IPR029069 HotDog domain A616_RS22545 ff5203780dfa963b4daa60038f32180c 234 Gene3D G3DSA:3.60.15.10 1 225 2.5E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22545 ff5203780dfa963b4daa60038f32180c 234 SMART SM00849 21 203 1.6E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22545 ff5203780dfa963b4daa60038f32180c 234 Pfam PF00753 Metallo-beta-lactamase superfamily 24 189 1.6E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22545 ff5203780dfa963b4daa60038f32180c 234 SUPERFAMILY SSF56281 3 220 1.57E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS00015 b673d484d19fce0f9568a95805b54f3f 71 Gene3D G3DSA:3.10.290.10 1 70 1.0E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS00015 b673d484d19fce0f9568a95805b54f3f 71 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 62 1.7E-27 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA A616_RS00015 b673d484d19fce0f9568a95805b54f3f 71 Pfam PF13275 S4 domain 4 68 1.3E-26 T 29-03-2018 A616_RS00015 b673d484d19fce0f9568a95805b54f3f 71 SUPERFAMILY SSF55174 2 66 2.21E-17 T 29-03-2018 A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 SUPERFAMILY SSF46785 7 138 5.04E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 SMART SM00347 24 123 1.1E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 Gene3D G3DSA:1.10.10.10 1 142 1.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS08035 c6fce57cee327605496c5316e2f2e77d 142 Pfam PF01047 MarR family 32 88 8.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02945 e595383da48b7d7e8ed6d29552193400 156 Gene3D G3DSA:3.40.50.300 1 150 2.9E-47 T 29-03-2018 A616_RS02945 e595383da48b7d7e8ed6d29552193400 156 SUPERFAMILY SSF52540 24 137 4.07E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02945 e595383da48b7d7e8ed6d29552193400 156 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 11 135 2.7E-36 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A616_RS02945 e595383da48b7d7e8ed6d29552193400 156 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 129 8.1E-36 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A616_RS23600 25fc81f9ae24b0f38cbfbecdf91d7a84 232 SMART SM00448 2 115 1.3E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23600 25fc81f9ae24b0f38cbfbecdf91d7a84 232 Pfam PF00072 Response regulator receiver domain 4 115 3.3E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23600 25fc81f9ae24b0f38cbfbecdf91d7a84 232 Gene3D G3DSA:1.10.10.10 141 232 3.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23600 25fc81f9ae24b0f38cbfbecdf91d7a84 232 Gene3D G3DSA:3.40.50.2300 1 140 4.4E-33 T 29-03-2018 A616_RS23600 25fc81f9ae24b0f38cbfbecdf91d7a84 232 SUPERFAMILY SSF52172 1 139 1.57E-38 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23600 25fc81f9ae24b0f38cbfbecdf91d7a84 232 PIRSF PIRSF006171 1 230 3.0E-74 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 Gene3D G3DSA:1.10.443.10 116 296 2.9E-47 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 13 302 3.7E-106 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 11 94 1.3E-22 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 Pfam PF00589 Phage integrase family 116 288 2.8E-47 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 9 302 56.773 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 SUPERFAMILY SSF56349 14 294 1.24E-55 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS20075 14b1ed0788a6e68e2c46ebabd6161254 313 Gene3D G3DSA:1.10.150.130 8 115 2.9E-25 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS00415 c7c32704443fa4719aeebd4f3ab76aeb 117 SUPERFAMILY SSF88659 45 112 1.46E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS00415 c7c32704443fa4719aeebd4f3ab76aeb 117 Gene3D G3DSA:1.10.10.10 49 115 1.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21695 9d40e28b83409840e99adcab50eaadb3 233 Pfam PF00005 ABC transporter 28 175 4.2E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS21695 9d40e28b83409840e99adcab50eaadb3 233 SUPERFAMILY SSF52540 8 230 2.6E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21695 9d40e28b83409840e99adcab50eaadb3 233 Gene3D G3DSA:3.40.50.300 3 233 1.6E-71 T 29-03-2018 A616_RS21695 9d40e28b83409840e99adcab50eaadb3 233 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS21695 9d40e28b83409840e99adcab50eaadb3 233 SMART SM00382 36 224 1.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS21275 6a0479c2ac5ce36b1275dfe7f4cc45a7 236 Pfam PF05949 Bacterial protein of unknown function (DUF881) 93 235 5.4E-46 T 29-03-2018 IPR010273 Protein of unknown function DUF881 A616_RS21275 6a0479c2ac5ce36b1275dfe7f4cc45a7 236 Gene3D G3DSA:1.20.5.50 14 129 4.3E-6 T 29-03-2018 A616_RS22825 078247fee1222d141acf988c677e63ba 329 Gene3D G3DSA:3.40.50.300 2 329 1.9E-78 T 29-03-2018 A616_RS22825 078247fee1222d141acf988c677e63ba 329 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS22825 078247fee1222d141acf988c677e63ba 329 SMART SM00382 34 233 8.8E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS22825 078247fee1222d141acf988c677e63ba 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.0E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS22825 078247fee1222d141acf988c677e63ba 329 SUPERFAMILY SSF52540 5 253 1.44E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22825 078247fee1222d141acf988c677e63ba 329 Pfam PF00005 ABC transporter 25 183 2.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS22825 078247fee1222d141acf988c677e63ba 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 321 3.7E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28755 80f7c09cee24ee6819d695c20d6580b9 474 Pfam PF06527 TniQ 41 182 8.9E-16 T 29-03-2018 IPR009492 TniQ A616_RS28755 80f7c09cee24ee6819d695c20d6580b9 474 Gene3D G3DSA:1.10.260.40 247 430 1.1E-6 T 29-03-2018 A616_RS28755 80f7c09cee24ee6819d695c20d6580b9 474 SUPERFAMILY SSF47413 261 319 2.7E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS18230 e9437cf47d8fbcf1409ed672c3025a2a 116 Pfam PF06108 Protein of unknown function (DUF952) 10 98 8.9E-22 T 29-03-2018 IPR009297 Protein of unknown function DUF952 A616_RS18230 e9437cf47d8fbcf1409ed672c3025a2a 116 SUPERFAMILY SSF56399 5 107 1.55E-18 T 29-03-2018 A616_RS12360 12f54b42d6e99d6a1702c6e86dcf4e03 221 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 3 215 9.5E-58 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 A616_RS12360 12f54b42d6e99d6a1702c6e86dcf4e03 221 Pfam PF01144 Coenzyme A transferase 8 215 4.3E-50 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS12360 12f54b42d6e99d6a1702c6e86dcf4e03 221 Gene3D G3DSA:3.40.1080.10 1 221 2.8E-66 T 29-03-2018 A616_RS12360 12f54b42d6e99d6a1702c6e86dcf4e03 221 SMART SM00882 5 216 4.6E-59 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS12360 12f54b42d6e99d6a1702c6e86dcf4e03 221 SUPERFAMILY SSF100950 3 219 1.26E-64 T 29-03-2018 A616_RS11605 98f60dd8f01d0e6bae31b6bdd8c1f04f 334 Gene3D G3DSA:1.10.287.40 191 292 0.0011 T 29-03-2018 A616_RS11605 98f60dd8f01d0e6bae31b6bdd8c1f04f 334 Hamap MF_01562 UPF0365 protein . 4 324 48.285 T 29-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity A616_RS11605 98f60dd8f01d0e6bae31b6bdd8c1f04f 334 Pfam PF12127 SigmaW regulon antibacterial 10 320 3.5E-165 T 29-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity A616_RS09540 8b18c4577b7aa330b1ffd21f7d998da7 512 PIRSF PIRSF005690 32 510 9.1E-182 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS09540 8b18c4577b7aa330b1ffd21f7d998da7 512 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 46 495 4.3E-189 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS02505 77ab9db859d7f2db82ee844589d41046 120 Gene3D G3DSA:2.60.120.10 13 117 2.5E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS02505 77ab9db859d7f2db82ee844589d41046 120 SUPERFAMILY SSF51182 22 107 2.16E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS28365 5185ea1067ecb25f02fd8a129b5e754d 369 SUPERFAMILY SSF144052 1 357 3.27E-105 T 29-03-2018 A616_RS28365 5185ea1067ecb25f02fd8a129b5e754d 369 Pfam PF02073 Thermophilic metalloprotease (M29) 3 333 1.6E-57 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS28365 5185ea1067ecb25f02fd8a129b5e754d 369 Gene3D G3DSA:3.40.1830.10 2 162 4.0E-39 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS10680 cae298d9f1c980f7dc26693b8a82175f 376 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 367 57.055 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A616_RS10680 cae298d9f1c980f7dc26693b8a82175f 376 Gene3D G3DSA:3.20.20.105 1 372 1.5E-161 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A616_RS10680 cae298d9f1c980f7dc26693b8a82175f 376 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 369 1.6E-176 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A616_RS10680 cae298d9f1c980f7dc26693b8a82175f 376 SUPERFAMILY SSF51713 3 368 7.32E-162 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A616_RS10680 cae298d9f1c980f7dc26693b8a82175f 376 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 364 2.0E-91 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A616_RS10680 cae298d9f1c980f7dc26693b8a82175f 376 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 369 6.3E-167 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A616_RS02430 fae623858d11c8e199382958cd4afd59 375 Pfam PF00534 Glycosyl transferases group 1 192 349 2.4E-32 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS02430 fae623858d11c8e199382958cd4afd59 375 SUPERFAMILY SSF53756 9 371 3.06E-69 T 29-03-2018 A616_RS02430 fae623858d11c8e199382958cd4afd59 375 Gene3D G3DSA:3.40.50.2000 1 194 1.2E-13 T 29-03-2018 A616_RS02430 fae623858d11c8e199382958cd4afd59 375 Pfam PF13439 Glycosyltransferase Family 4 21 183 1.5E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS02430 fae623858d11c8e199382958cd4afd59 375 Gene3D G3DSA:3.40.50.2000 195 363 9.1E-37 T 29-03-2018 A616_RS14915 3bebe90d52fa63b637ac0fe9cc7822b2 535 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 63 243 1.5E-40 T 29-03-2018 IPR020051 SagB-type dehydrogenase domain A616_RS14915 3bebe90d52fa63b637ac0fe9cc7822b2 535 SUPERFAMILY SSF55469 422 528 3.0E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS14915 3bebe90d52fa63b637ac0fe9cc7822b2 535 Gene3D G3DSA:3.40.109.10 277 524 2.7E-21 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS14915 3bebe90d52fa63b637ac0fe9cc7822b2 535 Gene3D G3DSA:3.40.109.10 14 242 2.4E-21 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS14915 3bebe90d52fa63b637ac0fe9cc7822b2 535 Pfam PF00881 Nitroreductase family 104 240 2.9E-5 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS14915 3bebe90d52fa63b637ac0fe9cc7822b2 535 Pfam PF00881 Nitroreductase family 432 522 5.5E-6 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS10365 80ef415361f5347e913f7ac833168332 225 SUPERFAMILY SSF53474 4 223 2.27E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS10365 80ef415361f5347e913f7ac833168332 225 Gene3D G3DSA:3.40.50.1820 2 225 6.4E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS13060 c2e305929b1babe10120f64be62423fe 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 7.9E-16 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family A616_RS13060 c2e305929b1babe10120f64be62423fe 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 4 66 1.8E-25 T 29-03-2018 IPR009570 Stage III sporulation protein AC A616_RS31950 733b71554ee270ffc032bb12c2ba643e 491 Pfam PF01139 tRNA-splicing ligase RtcB 54 491 1.9E-80 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A616_RS31950 733b71554ee270ffc032bb12c2ba643e 491 SUPERFAMILY SSF103365 52 491 6.02E-87 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A616_RS01265 c8211aed85faed68651fc0dc85f29ab4 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 157 37.354 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A616_RS01265 c8211aed85faed68651fc0dc85f29ab4 157 Pfam PF02542 YgbB family 1 155 4.1E-66 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A616_RS01265 c8211aed85faed68651fc0dc85f29ab4 157 Gene3D G3DSA:3.30.1330.50 1 157 1.0E-74 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A616_RS01265 c8211aed85faed68651fc0dc85f29ab4 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A616_RS01265 c8211aed85faed68651fc0dc85f29ab4 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 157 3.0E-71 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A616_RS01265 c8211aed85faed68651fc0dc85f29ab4 157 SUPERFAMILY SSF69765 1 157 5.89E-67 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A616_RS29505 4998ccc6754693fc33550791bad4fa1d 390 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 4 370 8.0E-149 T 29-03-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001 A616_RS29505 4998ccc6754693fc33550791bad4fa1d 390 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 370 1.6E-92 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 A616_RS29505 4998ccc6754693fc33550791bad4fa1d 390 Gene3D G3DSA:3.40.50.2000 204 351 4.6E-23 T 29-03-2018 A616_RS29505 4998ccc6754693fc33550791bad4fa1d 390 SUPERFAMILY SSF53756 3 384 1.02E-98 T 29-03-2018 A616_RS29505 4998ccc6754693fc33550791bad4fa1d 390 Gene3D G3DSA:3.40.50.2000 4 203 2.7E-53 T 29-03-2018 A616_RS31440 1d7773f6c91777859aa76fdd11ad6435 586 SUPERFAMILY SSF88713 77 191 2.6E-15 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS31440 1d7773f6c91777859aa76fdd11ad6435 586 Gene3D G3DSA:3.20.20.370 42 277 2.1E-19 T 29-03-2018 A616_RS31440 1d7773f6c91777859aa76fdd11ad6435 586 Gene3D G3DSA:2.60.120.560 338 545 7.1E-7 T 29-03-2018 A616_RS31440 1d7773f6c91777859aa76fdd11ad6435 586 Pfam PF01522 Polysaccharide deacetylase 110 186 7.2E-6 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS04340 daabe0cedbb9dcfdc9d994352a60a28b 404 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 6 403 8.3E-139 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 A616_RS04340 daabe0cedbb9dcfdc9d994352a60a28b 404 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 195 403 2.4E-70 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A616_RS04340 daabe0cedbb9dcfdc9d994352a60a28b 404 Pfam PF07670 Nucleoside recognition 93 187 8.7E-9 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A616_RS04340 daabe0cedbb9dcfdc9d994352a60a28b 404 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.1E-23 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 Gene3D G3DSA:1.10.10.10 9 111 2.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 SUPERFAMILY SSF46785 7 138 9.52E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 SMART SM00347 27 127 1.1E-29 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 Gene3D G3DSA:1.10.287.100 112 144 5.3E-12 T 29-03-2018 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 Pfam PF01047 MarR family 34 92 3.8E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 6.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 6.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS09795 4c682d3651426c5a70155c646c4ff5a1 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1011 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 SMART SM00481 5 72 2.0E-32 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Pfam PF02811 PHP domain 6 177 8.9E-52 T 29-03-2018 IPR004013 PHP domain GO:0003824 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 SUPERFAMILY SSF89550 4 267 1.96E-35 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Pfam PF01336 OB-fold nucleic acid binding domain 974 1043 3.6E-8 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Pfam PF14579 Helix-hairpin-helix motif 791 878 6.4E-27 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Gene3D G3DSA:2.40.50.140 953 1048 2.3E-13 T 29-03-2018 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 295 716 4.8E-174 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Gene3D G3DSA:1.10.150.280 796 874 1.4E-5 T 29-03-2018 A616_RS07920 8529792a98a9b67989814396cd824ae5 1142 Gene3D G3DSA:3.20.20.140 2 252 2.3E-52 T 29-03-2018 A616_RS21670 36401ef913891bef4d4bef39bc882893 680 Gene3D G3DSA:2.60.120.260 87 148 1.2E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS21670 36401ef913891bef4d4bef39bc882893 680 Gene3D G3DSA:2.60.40.1310 149 360 7.9E-5 T 29-03-2018 A616_RS18775 cbd90a75c54be358588331358b3b3fc5 545 Gene3D G3DSA:1.10.10.60 462 512 1.5E-9 T 29-03-2018 A616_RS18775 cbd90a75c54be358588331358b3b3fc5 545 Pfam PF07905 Purine catabolism regulatory protein-like family 11 130 2.5E-36 T 29-03-2018 IPR012914 Purine catabolism PurC-like domain A616_RS18775 cbd90a75c54be358588331358b3b3fc5 545 Pfam PF13556 PucR C-terminal helix-turn-helix domain 476 534 4.8E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS19495 4350a9cd106301daa2850e986d94cb3f 319 SUPERFAMILY SSF52540 9 165 4.83E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19495 4350a9cd106301daa2850e986d94cb3f 319 Pfam PF01715 IPP transferase 42 287 1.9E-86 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A616_RS19495 4350a9cd106301daa2850e986d94cb3f 319 Gene3D G3DSA:3.40.50.300 5 199 3.3E-68 T 29-03-2018 A616_RS19495 4350a9cd106301daa2850e986d94cb3f 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 295 1.5E-103 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A616_RS19495 4350a9cd106301daa2850e986d94cb3f 319 Gene3D G3DSA:1.10.287.890 202 283 8.3E-28 T 29-03-2018 A616_RS19495 4350a9cd106301daa2850e986d94cb3f 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 310 31.185 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 SUPERFAMILY SSF52540 122 365 4.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 Gene3D G3DSA:3.30.300.130 1 96 3.1E-22 T 29-03-2018 IPR034904 Fe-S cluster assembly domain A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 SUPERFAMILY SSF117916 1 93 7.19E-22 T 29-03-2018 IPR034904 Fe-S cluster assembly domain A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 Pfam PF01883 Iron-sulfur cluster assembly protein 4 69 8.0E-21 T 29-03-2018 IPR002744 MIP18 family-like A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 Hamap MF_02040 Iron-sulfur cluster carrier protein. 112 361 32.68 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 121 360 3.7E-81 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A616_RS01580 c3aeb24f1beca7a5f18b169c00473565 370 Gene3D G3DSA:3.40.50.300 113 329 7.9E-49 T 29-03-2018 A616_RS08505 155f04715a3ee3da488b05795655c308 330 SUPERFAMILY SSF55729 56 315 8.41E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS08505 155f04715a3ee3da488b05795655c308 330 Gene3D G3DSA:3.40.630.30 20 129 0.051 T 29-03-2018 A616_RS08505 155f04715a3ee3da488b05795655c308 330 Gene3D G3DSA:3.40.630.30 154 325 1.8E-19 T 29-03-2018 A616_RS08505 155f04715a3ee3da488b05795655c308 330 Pfam PF00583 Acetyltransferase (GNAT) family 205 310 9.0E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS10745 f78fc0159e928cdcb42e2e17d2753632 186 Gene3D G3DSA:3.40.50.2300 145 178 0.2 T 29-03-2018 A616_RS10745 f78fc0159e928cdcb42e2e17d2753632 186 Gene3D G3DSA:3.40.50.720 2 134 9.4E-12 T 29-03-2018 A616_RS10745 f78fc0159e928cdcb42e2e17d2753632 186 SUPERFAMILY SSF51735 5 167 1.25E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS00280 12a1ab2a1c1b1c8fecae392f1805d626 342 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 65 302 3.9E-29 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 A616_RS00280 12a1ab2a1c1b1c8fecae392f1805d626 342 Gene3D G3DSA:3.20.20.140 3 317 3.6E-35 T 29-03-2018 A616_RS00280 12a1ab2a1c1b1c8fecae392f1805d626 342 SUPERFAMILY SSF89550 129 331 2.75E-30 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS00280 12a1ab2a1c1b1c8fecae392f1805d626 342 SUPERFAMILY SSF89550 60 85 2.75E-30 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS07605 f68a7988e7feb216db7f88f1e0b29153 226 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 222 2.1E-68 T 29-03-2018 IPR003744 Queuosine precursor transporter A616_RS07605 f68a7988e7feb216db7f88f1e0b29153 226 Pfam PF02592 Putative vitamin uptake transporter 57 217 1.5E-53 T 29-03-2018 IPR003744 Queuosine precursor transporter A616_RS05030 c1fd956f7616a65c586b67acbc46d85e 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.7E-23 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS05030 c1fd956f7616a65c586b67acbc46d85e 104 SUPERFAMILY SSF103481 6 101 2.35E-16 T 29-03-2018 A616_RS16050 50481f3f2c609c23ccf472bce1253395 184 Pfam PF01872 RibD C-terminal domain 4 175 1.7E-25 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A616_RS16050 50481f3f2c609c23ccf472bce1253395 184 Gene3D G3DSA:3.40.430.10 3 179 4.4E-39 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS16050 50481f3f2c609c23ccf472bce1253395 184 SUPERFAMILY SSF53597 3 180 2.09E-34 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A616_RS17960 591d9798c7ffcfc73108be6ec14188af 303 SUPERFAMILY SSF52540 2 229 5.43E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS17960 591d9798c7ffcfc73108be6ec14188af 303 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS17960 591d9798c7ffcfc73108be6ec14188af 303 SMART SM00382 29 211 2.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS17960 591d9798c7ffcfc73108be6ec14188af 303 Gene3D G3DSA:3.40.50.300 1 271 2.8E-59 T 29-03-2018 A616_RS17960 591d9798c7ffcfc73108be6ec14188af 303 Pfam PF00005 ABC transporter 21 160 2.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 SMART SM00079 52 266 0.0043 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 SMART SM00062 52 267 1.1E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 56 265 1.7E-63 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 74 87 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 Gene3D G3DSA:3.40.190.10 191 264 1.7E-13 T 29-03-2018 A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 SUPERFAMILY SSF53850 1 267 2.76E-66 T 29-03-2018 A616_RS12370 28e3b48b5fcff3a2b4215ddb60099224 272 Gene3D G3DSA:3.40.190.10 42 190 3.4E-42 T 29-03-2018 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 395 39.311 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 PIRSF PIRSF000521 4 397 5.3E-47 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 Gene3D G3DSA:3.90.1150.10 2 159 5.3E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 SUPERFAMILY SSF53383 10 394 3.34E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 Pfam PF00202 Aminotransferase class-III 15 392 9.4E-104 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 Gene3D G3DSA:3.40.640.10 160 287 7.6E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 Gene3D G3DSA:3.90.1150.10 288 400 6.7E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS21640 839cbe3c22e147e452677f4c82eb6634 404 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 217 254 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS02455 d366e3ba1fbd39e42641cb6d0395b76b 114 Gene3D G3DSA:2.60.120.10 1 114 4.6E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS02455 d366e3ba1fbd39e42641cb6d0395b76b 114 SUPERFAMILY SSF51182 7 104 6.86E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS02455 d366e3ba1fbd39e42641cb6d0395b76b 114 Pfam PF07883 Cupin domain 36 101 3.9E-18 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 Gene3D G3DSA:1.20.140.10 218 378 2.5E-62 T 29-03-2018 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 SUPERFAMILY SSF47203 228 377 2.39E-58 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 5.5E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 Gene3D G3DSA:2.40.110.10 121 217 1.5E-36 T 29-03-2018 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 8.6E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 SUPERFAMILY SSF56645 1 242 6.41E-80 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.1E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 Gene3D G3DSA:1.10.540.10 1 119 1.1E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS11700 da93a85632b0ba60ff7d80d908a72776 379 PIRSF PIRSF016578 4 375 2.8E-26 T 29-03-2018 A616_RS18195 e9f2a5d046c370f85cc1c1e4f796d475 119 Gene3D G3DSA:3.40.50.360 1 119 9.8E-19 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS18195 e9f2a5d046c370f85cc1c1e4f796d475 119 TIGRFAM TIGR00333 nrdI: nrdI protein 3 114 6.5E-38 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A616_RS18195 e9f2a5d046c370f85cc1c1e4f796d475 119 Hamap MF_00128 Protein NrdI [nrdI]. 1 119 26.01 T 29-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial A616_RS18195 e9f2a5d046c370f85cc1c1e4f796d475 119 Pfam PF07972 NrdI Flavodoxin like 3 110 8.4E-32 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A616_RS18195 e9f2a5d046c370f85cc1c1e4f796d475 119 PIRSF PIRSF005087 1 119 7.8E-39 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI A616_RS18195 e9f2a5d046c370f85cc1c1e4f796d475 119 SUPERFAMILY SSF52218 1 113 6.84E-21 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 Pfam PF00072 Response regulator receiver domain 6 115 3.9E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 SUPERFAMILY SSF52172 2 127 5.41E-46 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 1.5E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 SUPERFAMILY SSF46894 135 229 1.7E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 Gene3D G3DSA:3.40.50.2300 3 125 6.3E-43 T 29-03-2018 A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 SMART SM00448 4 114 2.6E-50 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 Gene3D G3DSA:1.10.10.10 126 232 4.0E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05290 7b62f3e211ead9efcd82d6f93e9c11d0 232 SMART SM00862 154 228 3.8E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS13880 96f0c5b9b8ad798e4d50f1bec03020af 140 Pfam PF10673 Protein of unknown function (DUF2487) 11 76 7.8E-10 T 29-03-2018 IPR019615 Protein of unknown function DUF2487 A616_RS09210 a9a54a3cb22e2bb14bed47aa145e8b6c 392 Gene3D G3DSA:2.40.50.100 211 389 9.1E-5 T 29-03-2018 A616_RS09210 a9a54a3cb22e2bb14bed47aa145e8b6c 392 Pfam PF13437 HlyD family secretion protein 215 284 2.7E-7 T 29-03-2018 A616_RS09210 a9a54a3cb22e2bb14bed47aa145e8b6c 392 Gene3D G3DSA:2.40.50.100 58 94 0.059 T 29-03-2018 A616_RS09210 a9a54a3cb22e2bb14bed47aa145e8b6c 392 Pfam PF13533 Biotin-lipoyl like 83 116 8.5E-6 T 29-03-2018 A616_RS09210 a9a54a3cb22e2bb14bed47aa145e8b6c 392 Gene3D G3DSA:2.40.50.100 95 210 3.2E-6 T 29-03-2018 A616_RS29210 6be95fd185e6814f8079670444720b54 249 Pfam PF00977 Histidine biosynthesis protein 5 232 2.8E-79 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 A616_RS29210 6be95fd185e6814f8079670444720b54 249 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 5 237 7.1E-84 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A616_RS29210 6be95fd185e6814f8079670444720b54 249 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 240 37.239 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A616_RS29210 6be95fd185e6814f8079670444720b54 249 SUPERFAMILY SSF51366 4 240 1.57E-72 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS29210 6be95fd185e6814f8079670444720b54 249 Gene3D G3DSA:3.20.20.70 4 245 1.8E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS04940 99461a4528a6d1831bc3f5684c83de06 232 Pfam PF04172 LrgB-like family 12 222 5.7E-55 T 29-03-2018 IPR007300 CidB/LrgB family A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 33 53 4.7E-31 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 75 91 4.7E-31 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 170 191 4.7E-31 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 4.7E-31 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 55 71 4.7E-31 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 124 147 4.7E-31 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 Pfam PF00459 Inositol monophosphatase family 1 252 3.7E-49 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 Gene3D G3DSA:3.40.190.80 144 257 7.2E-20 T 29-03-2018 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 SUPERFAMILY SSF56655 1 257 1.24E-62 T 29-03-2018 A616_RS23550 f78960c910954d2d2e95ff0050ddba6f 258 Gene3D G3DSA:3.30.540.10 1 143 6.7E-39 T 29-03-2018 A616_RS09070 85d97902dda3f9e79afd255986a42af1 352 Pfam PF03576 Peptidase family S58 21 341 1.6E-107 T 29-03-2018 IPR005321 Peptidase S58, DmpA A616_RS09070 85d97902dda3f9e79afd255986a42af1 352 SUPERFAMILY SSF56266 4 339 6.54E-97 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS09070 85d97902dda3f9e79afd255986a42af1 352 Gene3D G3DSA:3.60.70.12 3 352 1.0E-106 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 Gene3D G3DSA:3.40.50.200 136 438 7.6E-97 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 Pfam PF00082 Subtilase family 181 424 1.8E-44 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 Gene3D G3DSA:3.30.70.80 74 135 0.0016 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 222 232 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 199 7.2E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 PRINTS PR00723 Subtilisin serine protease family (S8) signature 218 231 7.2E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 PRINTS PR00723 Subtilisin serine protease family (S8) signature 373 389 7.2E-19 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 185 196 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 374 384 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A616_RS11930 687ed7933fd5ed034c1a0f4a4f0a06e0 466 SUPERFAMILY SSF52743 161 434 4.19E-96 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A616_RS20950 a19aa8370f0f7dafd9b92ab44ca9ddd5 391 SMART SM00382 143 280 6.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20950 a19aa8370f0f7dafd9b92ab44ca9ddd5 391 Gene3D G3DSA:1.25.20.10 4 45 2.9E-4 T 29-03-2018 A616_RS20950 a19aa8370f0f7dafd9b92ab44ca9ddd5 391 SUPERFAMILY SSF52540 118 352 3.91E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20950 a19aa8370f0f7dafd9b92ab44ca9ddd5 391 Gene3D G3DSA:3.40.50.300 46 286 4.9E-25 T 29-03-2018 A616_RS20950 a19aa8370f0f7dafd9b92ab44ca9ddd5 391 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 147 277 1.5E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A616_RS20950 a19aa8370f0f7dafd9b92ab44ca9ddd5 391 Gene3D G3DSA:1.10.8.60 287 372 4.5E-11 T 29-03-2018 A616_RS07695 ffe9bdcd1247f41e7c3f4ca489c9ea86 333 SUPERFAMILY SSF53807 72 331 2.94E-53 T 29-03-2018 A616_RS07695 ffe9bdcd1247f41e7c3f4ca489c9ea86 333 Gene3D G3DSA:3.40.50.1980 73 175 2.5E-23 T 29-03-2018 A616_RS07695 ffe9bdcd1247f41e7c3f4ca489c9ea86 333 Gene3D G3DSA:3.40.50.1980 176 333 5.9E-30 T 29-03-2018 A616_RS07695 ffe9bdcd1247f41e7c3f4ca489c9ea86 333 Pfam PF01497 Periplasmic binding protein 77 307 4.4E-36 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS02350 90873a3cfa556519d8ccdf77e431605f 233 PIRSF PIRSF021383 1 225 2.3E-53 T 29-03-2018 IPR014197 Sporulation protein YunB A616_RS02350 90873a3cfa556519d8ccdf77e431605f 233 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 122 210 7.4E-31 T 29-03-2018 IPR014197 Sporulation protein YunB A616_RS02350 90873a3cfa556519d8ccdf77e431605f 233 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 11 213 1.5E-54 T 29-03-2018 IPR014197 Sporulation protein YunB A616_RS19550 2d8e67f59f19767f4e86913509944c6d 280 SUPERFAMILY SSF55681 9 251 2.49E-48 T 29-03-2018 A616_RS19550 2d8e67f59f19767f4e86913509944c6d 280 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 2 273 37.337 T 29-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 A616_RS19550 2d8e67f59f19767f4e86913509944c6d 280 Gene3D G3DSA:3.30.930.10 15 279 2.5E-30 T 29-03-2018 A616_RS19550 2d8e67f59f19767f4e86913509944c6d 280 Pfam PF03099 Biotin/lipoate A/B protein ligase family 116 174 2.3E-5 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 SUPERFAMILY SSF54631 110 214 6.59E-19 T 29-03-2018 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 SMART SM01240 8 487 7.7E-182 T 29-03-2018 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 Gene3D G3DSA:3.20.20.70 3 483 7.0E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 SUPERFAMILY SSF51412 231 491 4.84E-100 T 29-03-2018 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 SUPERFAMILY SSF51412 4 100 4.84E-100 T 29-03-2018 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 PIRSF PIRSF000130 3 499 7.6E-136 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 307 319 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A616_RS03870 d3a26a8d8524a6c7df77c4eb7936c7ae 499 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 11 487 8.8E-110 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A616_RS04625 5c3f4a6cd9e4c6afc76ff88360da5a72 307 SUPERFAMILY SSF161098 91 289 1.96E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS04625 5c3f4a6cd9e4c6afc76ff88360da5a72 307 Gene3D G3DSA:1.10.3720.10 2 293 3.3E-42 T 29-03-2018 A616_RS04625 5c3f4a6cd9e4c6afc76ff88360da5a72 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 4.9E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS26825 ce12d65ff02a8f2116155d454d1175ac 396 Gene3D G3DSA:3.40.640.10 47 302 7.1E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS26825 ce12d65ff02a8f2116155d454d1175ac 396 Pfam PF00155 Aminotransferase class I and II 33 383 3.2E-53 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS26825 ce12d65ff02a8f2116155d454d1175ac 396 Gene3D G3DSA:3.90.1150.10 303 387 1.3E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS26825 ce12d65ff02a8f2116155d454d1175ac 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A616_RS26825 ce12d65ff02a8f2116155d454d1175ac 396 SUPERFAMILY SSF53383 2 385 3.81E-99 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS23560 1dac98052d8b0c52721da387b304f026 162 SUPERFAMILY SSF54637 39 159 3.23E-30 T 29-03-2018 IPR029069 HotDog domain A616_RS23560 1dac98052d8b0c52721da387b304f026 162 Gene3D G3DSA:3.10.129.10 19 162 1.5E-30 T 29-03-2018 A616_RS23560 1dac98052d8b0c52721da387b304f026 162 Pfam PF03061 Thioesterase superfamily 72 146 1.8E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS23560 1dac98052d8b0c52721da387b304f026 162 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 40 154 2.2E-22 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A616_RS01150 4ecfbc6c873e81122cb5e7f393b3c876 123 Pfam PF02152 Dihydroneopterin aldolase 4 114 4.8E-32 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A616_RS01150 4ecfbc6c873e81122cb5e7f393b3c876 123 SMART SM00905 4 116 9.3E-46 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A616_RS01150 4ecfbc6c873e81122cb5e7f393b3c876 123 Gene3D G3DSA:3.30.1130.10 1 123 1.7E-32 T 29-03-2018 A616_RS01150 4ecfbc6c873e81122cb5e7f393b3c876 123 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 7.4E-32 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A616_RS01150 4ecfbc6c873e81122cb5e7f393b3c876 123 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 7.5E-37 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A616_RS01150 4ecfbc6c873e81122cb5e7f393b3c876 123 SUPERFAMILY SSF55620 2 118 1.39E-36 T 29-03-2018 A616_RS10180 5c480c21b2e2d845ff6cde6355bdd711 310 SUPERFAMILY SSF161098 89 287 9.59E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS10180 5c480c21b2e2d845ff6cde6355bdd711 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 5.4E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS10180 5c480c21b2e2d845ff6cde6355bdd711 310 Gene3D G3DSA:1.10.3720.10 1 293 2.3E-35 T 29-03-2018 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 137 26.68 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site A616_RS08770 530df9e009912445ae215b19b0bd3615 153 SUPERFAMILY SSF81330 10 130 4.18E-36 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 128 8.2E-42 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 116 1.4E-40 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 98 107 2.2E-12 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.2E-12 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS08770 530df9e009912445ae215b19b0bd3615 153 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 89 97 2.2E-12 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 A616_RS23945 473d9b86cb92ca599dbdf6a11ce8f9e6 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A616_RS23945 473d9b86cb92ca599dbdf6a11ce8f9e6 138 Pfam PF02082 Transcriptional regulator 1 83 2.5E-28 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS23945 473d9b86cb92ca599dbdf6a11ce8f9e6 138 SUPERFAMILY SSF46785 2 129 4.3E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23945 473d9b86cb92ca599dbdf6a11ce8f9e6 138 Gene3D G3DSA:1.10.10.10 1 136 2.1E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23945 473d9b86cb92ca599dbdf6a11ce8f9e6 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 126 2.4E-38 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS18440 0fd737b3a33968f30f60dcd9b2063384 130 Pfam PF06803 Protein of unknown function (DUF1232) 72 107 4.5E-13 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 A616_RS31170 dd4b38a4bfc0fa4121fa68f4614c6b43 287 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS31170 dd4b38a4bfc0fa4121fa68f4614c6b43 287 SUPERFAMILY SSF52540 4 229 8.31E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31170 dd4b38a4bfc0fa4121fa68f4614c6b43 287 SMART SM00382 28 217 1.3E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31170 dd4b38a4bfc0fa4121fa68f4614c6b43 287 Gene3D G3DSA:3.40.50.300 3 280 4.2E-61 T 29-03-2018 A616_RS31170 dd4b38a4bfc0fa4121fa68f4614c6b43 287 Pfam PF00005 ABC transporter 20 167 4.1E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS09325 6098bdd00f0218defcc92ba2bed2036a 405 Gene3D G3DSA:2.30.40.10 2 79 1.7E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09325 6098bdd00f0218defcc92ba2bed2036a 405 Pfam PF07969 Amidohydrolase family 112 378 2.0E-18 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS09325 6098bdd00f0218defcc92ba2bed2036a 405 Gene3D G3DSA:3.20.20.140 80 354 3.3E-29 T 29-03-2018 A616_RS09325 6098bdd00f0218defcc92ba2bed2036a 405 SUPERFAMILY SSF51556 68 373 2.22E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS09325 6098bdd00f0218defcc92ba2bed2036a 405 SUPERFAMILY SSF51338 5 90 9.0E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS07310 c3f875d21ec4a63b371c365f2fd77647 210 SMART SM00855 2 162 1.2E-22 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS07310 c3f875d21ec4a63b371c365f2fd77647 210 PIRSF PIRSF000709 2 179 3.5E-14 T 29-03-2018 A616_RS07310 c3f875d21ec4a63b371c365f2fd77647 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 179 5.5E-48 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A616_RS07310 c3f875d21ec4a63b371c365f2fd77647 210 SUPERFAMILY SSF53254 1 190 4.57E-51 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS07310 c3f875d21ec4a63b371c365f2fd77647 210 Gene3D G3DSA:3.40.50.1240 1 204 3.5E-49 T 29-03-2018 IPR029033 Histidine phosphatase superfamily A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 Pfam PF12146 Serine aminopeptidase, S33 16 243 5.2E-25 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 SUPERFAMILY SSF53474 8 256 2.61E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 4.1E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 4.1E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 4.1E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 4.1E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS22060 a6d88548eea04c28884d2607ad60872b 261 Gene3D G3DSA:3.40.50.1820 5 258 4.6E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01570 cd7c4119649a78fdd661c91fda30dfa8 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 3.3E-46 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A616_RS01570 cd7c4119649a78fdd661c91fda30dfa8 130 SUPERFAMILY SSF54211 6 130 6.83E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS01570 cd7c4119649a78fdd661c91fda30dfa8 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.783 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid A616_RS01570 cd7c4119649a78fdd661c91fda30dfa8 130 Gene3D G3DSA:3.30.230.10 3 130 8.6E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS01570 cd7c4119649a78fdd661c91fda30dfa8 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 Gene3D G3DSA:2.30.38.10 334 415 5.5E-26 T 29-03-2018 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 Gene3D G3DSA:3.40.50.980 7 180 7.1E-42 T 29-03-2018 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 SUPERFAMILY SSF56801 8 518 1.7E-151 T 29-03-2018 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 Gene3D G3DSA:3.40.50.980 181 333 1.0E-39 T 29-03-2018 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 Pfam PF00501 AMP-binding enzyme 18 422 9.6E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 Gene3D G3DSA:3.30.300.30 417 521 1.2E-29 T 29-03-2018 A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 506 2.0E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS11840 cfc8ab5848ba61c00c6df8904017667d 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS11355 f99705c993ddd8f7d553501d7eb866ac 155 SUPERFAMILY SSF55298 1 152 5.5E-53 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS11355 f99705c993ddd8f7d553501d7eb866ac 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 151 6.7E-33 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS11355 f99705c993ddd8f7d553501d7eb866ac 155 Gene3D G3DSA:3.30.1330.40 1 152 5.7E-25 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS20135 b66e1f32dffdea0f787b283b77ac216c 240 SMART SM00052 1 239 1.6E-9 T 29-03-2018 IPR001633 EAL domain A616_RS20135 b66e1f32dffdea0f787b283b77ac216c 240 Gene3D G3DSA:3.20.20.450 1 239 1.6E-44 T 29-03-2018 IPR001633 EAL domain A616_RS20135 b66e1f32dffdea0f787b283b77ac216c 240 SUPERFAMILY SSF141868 3 237 1.07E-45 T 29-03-2018 IPR001633 EAL domain A616_RS20135 b66e1f32dffdea0f787b283b77ac216c 240 Pfam PF00563 EAL domain 3 234 1.3E-38 T 29-03-2018 IPR001633 EAL domain A616_RS20820 62285b214cf808e97f737c3f97c6e56d 579 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 8.7E-153 T 29-03-2018 A616_RS20820 62285b214cf808e97f737c3f97c6e56d 579 Gene3D G3DSA:3.40.970.40 240 289 6.1E-11 T 29-03-2018 A616_RS20820 62285b214cf808e97f737c3f97c6e56d 579 Gene3D G3DSA:2.30.310.10 1 166 2.6E-48 T 29-03-2018 A616_RS20820 62285b214cf808e97f737c3f97c6e56d 579 Gene3D G3DSA:1.10.8.50 167 236 6.8E-24 T 29-03-2018 A616_RS20820 62285b214cf808e97f737c3f97c6e56d 579 Pfam PF05670 Domain of unknown function (DUF814) 454 538 4.3E-28 T 29-03-2018 IPR008532 Domain of unknown function DUF814 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-10 T 29-03-2018 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.0E-10 T 29-03-2018 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 99 107 3.3E-13 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 53 63 3.3E-13 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.3E-13 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 SUPERFAMILY SSF51905 2 175 1.14E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 Gene3D G3DSA:3.50.50.60 1 178 1.9E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07100 39a6bf9c2c81a015b7c5386dca9330fc 189 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 122 2.7E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 Gene3D G3DSA:1.10.357.10 90 226 2.8E-14 T 29-03-2018 A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 SUPERFAMILY SSF46689 25 85 6.67E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 SUPERFAMILY SSF48498 111 223 1.24E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 5.7E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 Gene3D G3DSA:1.10.10.60 24 88 5.5E-17 T 29-03-2018 A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 3.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS27300 6d932976b33cf581f64c30ca80923cf4 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 3.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS28875 d873d959368663f396aad552e400702c 361 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 41 59 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A616_RS28875 d873d959368663f396aad552e400702c 361 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 312 1.3E-58 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS28875 d873d959368663f396aad552e400702c 361 Gene3D G3DSA:3.40.50.1100 29 146 5.0E-26 T 29-03-2018 A616_RS28875 d873d959368663f396aad552e400702c 361 SUPERFAMILY SSF53686 12 328 3.8E-79 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A616_RS28875 d873d959368663f396aad552e400702c 361 Gene3D G3DSA:3.40.50.1100 147 333 4.2E-45 T 29-03-2018 A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 443 2.4E-81 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 Gene3D G3DSA:3.40.190.10 149 283 1.3E-37 T 29-03-2018 A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 Gene3D G3DSA:3.10.105.10 284 500 1.1E-50 T 29-03-2018 A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 557 587 0.0024 T 29-03-2018 A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 Gene3D G3DSA:3.90.76.10 55 148 1.2E-22 T 29-03-2018 A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 PIRSF PIRSF002741 22 522 3.5E-98 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS12775 fee0a07543e690a1d376e81d2de6ff61 591 SUPERFAMILY SSF53850 27 516 3.08E-122 T 29-03-2018 A616_RS04480 520c5dc0b5c8ea87315ef2418f77d60b 152 Gene3D G3DSA:3.40.630.30 83 143 3.8E-10 T 29-03-2018 A616_RS04480 520c5dc0b5c8ea87315ef2418f77d60b 152 SUPERFAMILY SSF55729 1 145 4.46E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS04480 520c5dc0b5c8ea87315ef2418f77d60b 152 Gene3D G3DSA:3.40.630.30 1 82 4.3E-11 T 29-03-2018 A616_RS04480 520c5dc0b5c8ea87315ef2418f77d60b 152 Pfam PF13673 Acetyltransferase (GNAT) domain 47 134 1.2E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Gene3D G3DSA:3.40.50.800 533 637 4.5E-28 T 29-03-2018 IPR004154 Anticodon-binding A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Gene3D G3DSA:3.30.930.10 230 532 4.0E-123 T 29-03-2018 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 2.0E-14 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 68 635 35.232 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 SUPERFAMILY SSF81271 4 63 8.72E-16 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Pfam PF02824 TGS domain 4 63 3.8E-13 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Gene3D G3DSA:3.30.980.10 70 229 1.6E-46 T 29-03-2018 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 508 521 3.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 3.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 465 493 3.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 547 3.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 3.6E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 SUPERFAMILY SSF52954 528 636 1.66E-31 T 29-03-2018 IPR004154 Anticodon-binding A616_RS09415 52531b532644816d0c5d1a4c72465093 637 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 74 632 1.8E-235 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 530 1.9E-41 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 SUPERFAMILY SSF55186 65 243 1.57E-63 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Gene3D G3DSA:3.10.20.30 1 64 6.9E-18 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS09415 52531b532644816d0c5d1a4c72465093 637 SUPERFAMILY SSF55681 245 527 3.58E-95 T 29-03-2018 A616_RS09415 52531b532644816d0c5d1a4c72465093 637 Pfam PF03129 Anticodon binding domain 542 631 2.4E-25 T 29-03-2018 IPR004154 Anticodon-binding A616_RS09415 52531b532644816d0c5d1a4c72465093 637 SMART SM00863 172 221 9.2E-23 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A616_RS25435 d4268ea71f085133ef42f319e5214b24 291 SUPERFAMILY SSF141571 63 99 7.98E-24 T 29-03-2018 A616_RS25435 d4268ea71f085133ef42f319e5214b24 291 SUPERFAMILY SSF141571 163 278 7.98E-24 T 29-03-2018 A616_RS25435 d4268ea71f085133ef42f319e5214b24 291 Gene3D G3DSA:2.160.20.80 44 275 2.5E-28 T 29-03-2018 A616_RS25435 d4268ea71f085133ef42f319e5214b24 291 Pfam PF00805 Pentapeptide repeats (8 copies) 200 236 8.7E-12 T 29-03-2018 IPR001646 Pentapeptide repeat A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 196 401 2.9E-43 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 323 8.2E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 Gene3D G3DSA:3.90.1170.30 20 115 8.1E-4 T 29-03-2018 A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 Gene3D G3DSA:2.40.50.100 212 377 1.3E-6 T 29-03-2018 A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 SUPERFAMILY SSF111369 61 129 3.27E-6 T 29-03-2018 A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 Gene3D G3DSA:1.10.287.470 126 185 3.3E-9 T 29-03-2018 A616_RS18815 961a6fc8c0b11087f6bf0d8db52fb5a0 404 SUPERFAMILY SSF111369 195 327 1.96E-12 T 29-03-2018 A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.8E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 Gene3D G3DSA:1.10.10.60 1 61 2.5E-16 T 29-03-2018 A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 SUPERFAMILY SSF46689 3 74 1.95E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 SUPERFAMILY SSF48498 81 188 9.69E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 Pfam PF08359 YsiA-like protein, C-terminal region 115 159 3.2E-4 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 Gene3D G3DSA:1.10.357.10 62 189 4.9E-15 T 29-03-2018 A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS28395 220bffce636e38516d1d3628f1e200b4 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14540 06d438fd8409f225b9a2ba76a1af0e26 310 Pfam PF13280 WYL domain 137 305 3.4E-35 T 29-03-2018 IPR026881 WYL domain A616_RS14540 06d438fd8409f225b9a2ba76a1af0e26 310 Gene3D G3DSA:1.10.10.10 1 64 5.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14540 06d438fd8409f225b9a2ba76a1af0e26 310 PIRSF PIRSF016838 1 310 7.3E-35 T 29-03-2018 IPR028349 Protein PafC A616_RS14540 06d438fd8409f225b9a2ba76a1af0e26 310 SUPERFAMILY SSF46785 2 61 4.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14540 06d438fd8409f225b9a2ba76a1af0e26 310 Pfam PF08279 HTH domain 5 59 1.3E-14 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS03730 1cee0ce60016d28ddea50fffefeb7811 381 Gene3D G3DSA:2.60.120.200 108 170 0.003 T 29-03-2018 A616_RS03730 1cee0ce60016d28ddea50fffefeb7811 381 Gene3D G3DSA:2.60.120.200 13 107 3.9E-6 T 29-03-2018 A616_RS03730 1cee0ce60016d28ddea50fffefeb7811 381 SUPERFAMILY SSF49899 12 140 1.06E-13 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 4.0E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 323 3.0E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 Gene3D G3DSA:3.40.50.300 4 336 1.5E-82 T 29-03-2018 A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 SUPERFAMILY SSF52540 35 322 2.28E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 Pfam PF00005 ABC transporter 28 186 3.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS01070 4b8f231dab710260f59e0491246daaf7 341 SMART SM00382 36 236 5.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS22840 0807dcc65d6e6b6cbe8f901a2f893360 532 Gene3D G3DSA:3.90.76.10 63 152 4.2E-29 T 29-03-2018 A616_RS22840 0807dcc65d6e6b6cbe8f901a2f893360 532 Gene3D G3DSA:3.40.190.10 153 296 2.6E-33 T 29-03-2018 A616_RS22840 0807dcc65d6e6b6cbe8f901a2f893360 532 PIRSF PIRSF002741 3 532 2.4E-110 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS22840 0807dcc65d6e6b6cbe8f901a2f893360 532 Gene3D G3DSA:3.10.105.10 297 501 9.5E-57 T 29-03-2018 A616_RS22840 0807dcc65d6e6b6cbe8f901a2f893360 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 441 3.6E-85 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS22840 0807dcc65d6e6b6cbe8f901a2f893360 532 SUPERFAMILY SSF53850 37 530 3.26E-130 T 29-03-2018 A616_RS01305 d81a13834f234cb68deefb3151dc4379 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01305 d81a13834f234cb68deefb3151dc4379 49 SUPERFAMILY SSF57829 1 49 8.79E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A616_RS01305 d81a13834f234cb68deefb3151dc4379 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.675 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01305 d81a13834f234cb68deefb3151dc4379 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 8.0E-19 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01305 d81a13834f234cb68deefb3151dc4379 49 Pfam PF00471 Ribosomal protein L33 3 49 1.5E-20 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20245 dc5a841e2524a630670b79bbbd7859e9 90 Gene3D G3DSA:3.30.1320.10 2 85 3.0E-33 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20245 dc5a841e2524a630670b79bbbd7859e9 90 Pfam PF00886 Ribosomal protein S16 9 67 4.1E-24 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20245 dc5a841e2524a630670b79bbbd7859e9 90 SUPERFAMILY SSF54565 2 87 1.06E-34 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20245 dc5a841e2524a630670b79bbbd7859e9 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.691 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20245 dc5a841e2524a630670b79bbbd7859e9 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 3.1E-35 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS19665 c3854a8676835b13f045fe6864e77037 430 SUPERFAMILY SSF63411 281 423 8.5E-19 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A616_RS19665 c3854a8676835b13f045fe6864e77037 430 SUPERFAMILY SSF63411 13 219 4.4E-44 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A616_RS19665 c3854a8676835b13f045fe6864e77037 430 Gene3D G3DSA:3.30.830.10 6 220 5.1E-49 T 29-03-2018 A616_RS19665 c3854a8676835b13f045fe6864e77037 430 Pfam PF00675 Insulinase (Peptidase family M16) 62 174 6.2E-20 T 29-03-2018 IPR011765 Peptidase M16, N-terminal A616_RS19665 c3854a8676835b13f045fe6864e77037 430 Pfam PF05193 Peptidase M16 inactive domain 181 361 4.1E-18 T 29-03-2018 IPR007863 Peptidase M16, C-terminal A616_RS19665 c3854a8676835b13f045fe6864e77037 430 Gene3D G3DSA:3.30.830.10 221 430 3.1E-24 T 29-03-2018 A616_RS11730 e112f3c5327e5908d13a5b8f232bad44 494 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 305 3.8E-22 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A616_RS11730 e112f3c5327e5908d13a5b8f232bad44 494 SUPERFAMILY SSF53649 2 352 7.03E-40 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS11730 e112f3c5327e5908d13a5b8f232bad44 494 SUPERFAMILY SSF53649 409 486 7.03E-40 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS11730 e112f3c5327e5908d13a5b8f232bad44 494 Gene3D G3DSA:3.40.720.10 1 492 2.7E-30 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS27460 dfa05af76f781e9b1359aff0f109c4bc 253 Pfam PF00005 ABC transporter 21 180 7.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27460 dfa05af76f781e9b1359aff0f109c4bc 253 SMART SM00382 29 229 3.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27460 dfa05af76f781e9b1359aff0f109c4bc 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 251 4.2E-12 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A616_RS27460 dfa05af76f781e9b1359aff0f109c4bc 253 SUPERFAMILY SSF52540 4 250 2.3E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27460 dfa05af76f781e9b1359aff0f109c4bc 253 Gene3D G3DSA:3.40.50.300 1 252 1.9E-55 T 29-03-2018 A616_RS29935 3463ce9786204d34b0a213d149c7198b 122 Pfam PF03899 ATP synthase I chain 12 107 1.1E-7 T 29-03-2018 IPR005598 ATP synthase protein I A616_RS29935 3463ce9786204d34b0a213d149c7198b 122 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 31 106 5.0E-4 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 19 74 1.5E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Gene3D G3DSA:3.40.50.740 274 560 2.1E-81 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Gene3D G3DSA:2.40.40.20 561 715 5.6E-42 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Pfam PF00384 Molybdopterin oxidoreductase 77 510 9.1E-83 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 SMART SM00926 18 74 9.3E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Gene3D G3DSA:2.20.25.90 12 78 1.8E-19 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Gene3D G3DSA:3.40.50.740 79 195 1.2E-21 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 SUPERFAMILY SSF53706 16 605 6.28E-186 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Gene3D G3DSA:3.40.228.10 196 273 2.2E-23 T 29-03-2018 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 SUPERFAMILY SSF50692 575 715 1.99E-45 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 455 472 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A616_RS26125 09ff84f45da215b605bc36f3830e42f4 724 Pfam PF01568 Molydopterin dinucleotide binding domain 603 710 6.1E-30 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A616_RS02650 2320d6fb6755ff607945ef043ed33d57 416 Gene3D G3DSA:1.20.1250.20 215 399 2.5E-18 T 29-03-2018 A616_RS02650 2320d6fb6755ff607945ef043ed33d57 416 SUPERFAMILY SSF103473 10 398 1.57E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02650 2320d6fb6755ff607945ef043ed33d57 416 Pfam PF07690 Major Facilitator Superfamily 23 367 2.1E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS02650 2320d6fb6755ff607945ef043ed33d57 416 Gene3D G3DSA:1.20.1250.20 6 210 1.8E-16 T 29-03-2018 A616_RS00780 ef017b93370d42efbd2612a98bdc70c9 249 Pfam PF06738 Putative threonine/serine exporter 8 247 1.1E-69 T 29-03-2018 IPR010619 Putative threonine/serine exporter A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 Pfam PF00072 Response regulator receiver domain 4 112 2.3E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 Gene3D G3DSA:3.40.50.2300 1 124 1.7E-38 T 29-03-2018 A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 220 1.3E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 SUPERFAMILY SSF52172 3 166 3.13E-44 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 Gene3D G3DSA:1.10.10.10 125 223 9.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 SMART SM00862 147 220 1.9E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS23130 2ded506242bafc9428b774bad3a53b21 224 SMART SM00448 2 112 1.7E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 SUPERFAMILY SSF47240 4 144 5.94E-43 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS06785 769df54f0f296f075c7ade78c374414a 145 Gene3D G3DSA:1.20.1260.10 2 145 1.1E-45 T 29-03-2018 IPR012347 Ferritin-related A616_RS06785 769df54f0f296f075c7ade78c374414a 145 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 Pfam PF00210 Ferritin-like domain 9 145 2.0E-29 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 PIRSF PIRSF005900 2 145 8.1E-49 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 2.0E-15 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 2.0E-15 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS06785 769df54f0f296f075c7ade78c374414a 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 2.0E-15 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A616_RS26670 117701e99af28bf94dec188285fbf2dc 250 Gene3D G3DSA:3.20.20.370 17 247 1.0E-67 T 29-03-2018 A616_RS26670 117701e99af28bf94dec188285fbf2dc 250 SUPERFAMILY SSF88713 39 239 1.27E-70 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS26670 117701e99af28bf94dec188285fbf2dc 250 Pfam PF01522 Polysaccharide deacetylase 46 165 7.7E-37 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS01825 7e92b61b7fb2cc40da46bd1b44bc6c47 459 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A616_RS01825 7e92b61b7fb2cc40da46bd1b44bc6c47 459 PIRSF PIRSF006060 1 458 7.7E-67 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS01825 7e92b61b7fb2cc40da46bd1b44bc6c47 459 Pfam PF00324 Amino acid permease 14 443 9.9E-101 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 SUPERFAMILY SSF88946 2 100 1.49E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 176 3.0E-21 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 Pfam PF04545 Sigma-70, region 4 129 175 7.8E-12 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 SUPERFAMILY SSF88659 114 176 4.86E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 Gene3D G3DSA:1.10.1740.10 1 106 1.8E-20 T 29-03-2018 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 Pfam PF04542 Sigma-70 region 2 25 91 6.1E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS02970 78feff2e50b7fa0cf6fac1730332b288 193 Gene3D G3DSA:1.10.10.10 107 182 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11200 8a4a302d5eb9f5b1ea7de46bfa05fd20 187 Gene3D G3DSA:1.10.10.60 2 51 5.4E-11 T 29-03-2018 A616_RS11200 8a4a302d5eb9f5b1ea7de46bfa05fd20 187 Gene3D G3DSA:1.10.357.10 52 178 8.2E-9 T 29-03-2018 A616_RS11200 8a4a302d5eb9f5b1ea7de46bfa05fd20 187 SUPERFAMILY SSF46689 2 68 1.7E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS11200 8a4a302d5eb9f5b1ea7de46bfa05fd20 187 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 47 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS11200 8a4a302d5eb9f5b1ea7de46bfa05fd20 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 48 1.9E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS11200 8a4a302d5eb9f5b1ea7de46bfa05fd20 187 SUPERFAMILY SSF48498 90 183 1.48E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS25495 cec287a19e3e22ba4c654f019c832317 370 SUPERFAMILY SSF144052 1 357 3.4E-97 T 29-03-2018 A616_RS25495 cec287a19e3e22ba4c654f019c832317 370 Pfam PF02073 Thermophilic metalloprotease (M29) 3 335 2.6E-54 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS25495 cec287a19e3e22ba4c654f019c832317 370 Gene3D G3DSA:3.40.1830.10 2 163 3.3E-34 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS20090 d08672e4eafdfb04e2bad003debaf7c6 372 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 76 290 4.2E-79 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A616_RS20090 d08672e4eafdfb04e2bad003debaf7c6 372 Pfam PF02481 DNA recombination-mediator protein A 77 282 3.9E-79 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A616_RS20090 d08672e4eafdfb04e2bad003debaf7c6 372 Gene3D G3DSA:3.40.50.450 117 264 5.1E-39 T 29-03-2018 A616_RS20090 d08672e4eafdfb04e2bad003debaf7c6 372 SUPERFAMILY SSF102405 85 292 5.95E-41 T 29-03-2018 A616_RS20090 d08672e4eafdfb04e2bad003debaf7c6 372 Gene3D G3DSA:1.10.10.10 293 370 9.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25605 7db5842980a9f486cb01b45293044b59 64 Pfam PF10055 Uncharacterized small protein (DUF2292) 13 48 7.6E-19 T 29-03-2018 IPR018743 Protein of unknown function DUF2292 A616_RS27285 ea8b250ce61a61d7f625af85d3102fd0 410 Pfam PF07690 Major Facilitator Superfamily 13 265 8.1E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS27285 ea8b250ce61a61d7f625af85d3102fd0 410 Pfam PF07690 Major Facilitator Superfamily 270 401 3.5E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS27285 ea8b250ce61a61d7f625af85d3102fd0 410 Gene3D G3DSA:1.20.1250.20 1 196 2.7E-21 T 29-03-2018 A616_RS27285 ea8b250ce61a61d7f625af85d3102fd0 410 Gene3D G3DSA:1.20.1250.20 198 405 6.4E-12 T 29-03-2018 A616_RS27285 ea8b250ce61a61d7f625af85d3102fd0 410 SUPERFAMILY SSF103473 9 403 1.23E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 SUPERFAMILY SSF90123 491 780 7.98E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 SUPERFAMILY SSF52540 805 1014 2.01E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 SUPERFAMILY SSF56601 24 346 3.17E-83 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 491 1013 1.5E-112 T 29-03-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 Pfam PF00144 Beta-lactamase 29 349 2.3E-76 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 Gene3D G3DSA:1.20.1560.10 376 781 4.4E-21 T 29-03-2018 A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 Gene3D G3DSA:3.40.710.10 15 357 1.8E-83 T 29-03-2018 A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 Pfam PF00005 ABC transporter 826 958 5.6E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 SMART SM00382 832 1007 3.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS18470 aa1a71ec004ed6120d17b4569ef0a955 1017 Gene3D G3DSA:3.40.50.300 782 1017 5.1E-38 T 29-03-2018 A616_RS26600 08c3453cdc04c983fdb5088a78c0c78a 155 Pfam PF05995 Cysteine dioxygenase type I 47 152 1.5E-12 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 A616_RS26600 08c3453cdc04c983fdb5088a78c0c78a 155 Gene3D G3DSA:2.60.120.10 2 154 2.5E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS26600 08c3453cdc04c983fdb5088a78c0c78a 155 SUPERFAMILY SSF51182 4 153 3.65E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS26490 18169465f4b673f142bc238390e7875f 375 Pfam PF00149 Calcineurin-like phosphoesterase 3 197 1.8E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS26490 18169465f4b673f142bc238390e7875f 375 SUPERFAMILY SSF56300 4 298 2.85E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS26490 18169465f4b673f142bc238390e7875f 375 Gene3D G3DSA:3.60.21.10 2 253 1.9E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS19975 d2191ee93dd2d3c5c6d39c62e5c38de5 120 Gene3D G3DSA:3.40.50.2300 2 120 9.8E-41 T 29-03-2018 A616_RS19975 d2191ee93dd2d3c5c6d39c62e5c38de5 120 Pfam PF00072 Response regulator receiver domain 5 116 5.7E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS19975 d2191ee93dd2d3c5c6d39c62e5c38de5 120 SUPERFAMILY SSF52172 4 119 1.29E-40 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS19975 d2191ee93dd2d3c5c6d39c62e5c38de5 120 SMART SM00448 3 115 8.9E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS29240 485c4df636f66cb9f90ec4e0f3d48401 167 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 140 7.3E-9 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29240 485c4df636f66cb9f90ec4e0f3d48401 167 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 115 143 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A616_RS29240 485c4df636f66cb9f90ec4e0f3d48401 167 Gene3D G3DSA:2.160.10.10 56 167 8.5E-30 T 29-03-2018 A616_RS29240 485c4df636f66cb9f90ec4e0f3d48401 167 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 73 92 0.0017 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29240 485c4df636f66cb9f90ec4e0f3d48401 167 SUPERFAMILY SSF51161 10 161 4.02E-36 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 367 5.5E-121 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 359 3.4E-14 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 SUPERFAMILY SSF52540 244 344 1.73E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 SUPERFAMILY SSF52540 2 217 1.73E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 372 101.806 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A616_RS00020 1c7aa647e87a4c26d4021068ed75688d 372 Gene3D G3DSA:3.40.50.300 2 368 6.0E-27 T 29-03-2018 A616_RS01520 15a7590d4d7f631eaccee964d556484f 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01520 15a7590d4d7f631eaccee964d556484f 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.2E-24 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01520 15a7590d4d7f631eaccee964d556484f 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.278 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01520 15a7590d4d7f631eaccee964d556484f 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 8.0E-9 T 29-03-2018 A616_RS01520 15a7590d4d7f631eaccee964d556484f 37 Pfam PF00444 Ribosomal protein L36 1 37 2.9E-19 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01520 15a7590d4d7f631eaccee964d556484f 37 SUPERFAMILY SSF57840 1 37 8.24E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS11790 c6d0d90c4623dc12c3b6c5f72883544b 322 SMART SM00729 37 264 8.8E-43 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS11790 c6d0d90c4623dc12c3b6c5f72883544b 322 Pfam PF16199 Radical_SAM C-terminal domain 225 308 9.1E-25 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A616_RS11790 c6d0d90c4623dc12c3b6c5f72883544b 322 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 20 318 1.6E-125 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 A616_RS11790 c6d0d90c4623dc12c3b6c5f72883544b 322 Gene3D G3DSA:3.20.20.70 9 281 5.4E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS11790 c6d0d90c4623dc12c3b6c5f72883544b 322 SUPERFAMILY SSF102114 15 319 1.07E-54 T 29-03-2018 A616_RS11790 c6d0d90c4623dc12c3b6c5f72883544b 322 Pfam PF04055 Radical SAM superfamily 57 219 2.7E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS04820 c622616b94917b09b7e159d46167cd94 470 Pfam PF03606 C4-dicarboxylate anaerobic carrier 17 463 1.8E-80 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A616_RS12575 297666dca4efb674815bf37dcb0a6813 318 Hamap MF_01818 Ribonuclease BN [rbn]. 1 308 39.714 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A616_RS12575 297666dca4efb674815bf37dcb0a6813 318 Gene3D G3DSA:3.60.15.10 2 317 2.9E-64 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12575 297666dca4efb674815bf37dcb0a6813 318 Pfam PF12706 Beta-lactamase superfamily domain 201 270 1.7E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12575 297666dca4efb674815bf37dcb0a6813 318 Pfam PF12706 Beta-lactamase superfamily domain 32 147 8.5E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12575 297666dca4efb674815bf37dcb0a6813 318 SUPERFAMILY SSF56281 3 303 8.8E-80 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS12575 297666dca4efb674815bf37dcb0a6813 318 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 306 4.3E-108 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A616_RS12090 9164114c057e09bd40a49a73c0076205 504 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 7 504 46.148 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS12090 9164114c057e09bd40a49a73c0076205 504 Pfam PF00221 Aromatic amino acid lyase 15 471 7.1E-203 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A616_RS12090 9164114c057e09bd40a49a73c0076205 504 SUPERFAMILY SSF48557 5 500 3.3E-198 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 A616_RS12090 9164114c057e09bd40a49a73c0076205 504 Gene3D G3DSA:1.20.200.10 203 503 3.9E-132 T 29-03-2018 A616_RS12090 9164114c057e09bd40a49a73c0076205 504 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 8 500 2.6E-213 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A616_RS12090 9164114c057e09bd40a49a73c0076205 504 Gene3D G3DSA:1.10.275.10 1 201 3.0E-76 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal A616_RS12090 9164114c057e09bd40a49a73c0076205 504 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 143 159 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A616_RS07255 092f073dddcfd1cf8a92373fbcbc6f4a 696 Gene3D G3DSA:2.60.60.30 464 591 2.1E-11 T 29-03-2018 A616_RS19685 52117d06294048e856c05c17e46f3e05 357 Gene3D G3DSA:1.10.3470.10 8 339 1.5E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS19685 52117d06294048e856c05c17e46f3e05 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 335 1.6E-41 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Pfam PF07833 Copper amine oxidase N-terminal domain 646 711 2.1E-11 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Pfam PF07833 Copper amine oxidase N-terminal domain 596 650 2.4E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 SUPERFAMILY SSF55383 626 707 2.62E-17 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Gene3D G3DSA:2.60.40.1280 292 429 1.4E-6 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Gene3D G3DSA:2.60.40.1280 22 156 4.1E-6 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Gene3D G3DSA:2.60.40.1280 157 291 6.8E-7 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Gene3D G3DSA:3.30.457.10 626 691 3.0E-14 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS13290 21880d17be320ac30b1fff7a104dffca 714 Gene3D G3DSA:3.30.457.10 692 714 1.2E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS18550 046911a10b414b505315280461dc443e 145 Gene3D G3DSA:3.40.630.30 36 134 5.4E-17 T 29-03-2018 A616_RS18550 046911a10b414b505315280461dc443e 145 Gene3D G3DSA:1.10.287.900 2 35 2.8E-17 T 29-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 A616_RS18550 046911a10b414b505315280461dc443e 145 Pfam PF00583 Acetyltransferase (GNAT) family 12 128 2.1E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS18550 046911a10b414b505315280461dc443e 145 SUPERFAMILY SSF55729 1 134 7.09E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS10160 3592e95a43a53726dca9f2d018ee4cfb 341 Pfam PF06089 L-asparaginase II 6 327 1.6E-121 T 29-03-2018 IPR010349 L-asparaginase II A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.1E-34 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 SUPERFAMILY SSF55608 120 221 5.53E-19 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 Gene3D G3DSA:3.10.28.10 12 100 1.2E-13 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 Gene3D G3DSA:3.10.28.10 123 203 5.3E-19 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 2.7E-36 T 29-03-2018 A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 2.8E-125 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 8.4E-39 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain A616_RS29135 3ccfccff20093668de169e9baefcd5e9 315 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 34.869 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 A616_RS16485 cadd2c51304d12323eedff6a2ade5d63 179 Gene3D G3DSA:3.30.420.10 1 126 1.1E-19 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS16485 cadd2c51304d12323eedff6a2ade5d63 179 SUPERFAMILY SSF53098 2 124 2.53E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS16485 cadd2c51304d12323eedff6a2ade5d63 179 Pfam PF13456 Reverse transcriptase-like 6 124 6.1E-17 T 29-03-2018 A616_RS24540 3ba067889e0609f248ab2de5718a328a 474 Gene3D G3DSA:2.40.50.260 290 390 2.3E-4 T 29-03-2018 A616_RS24540 3ba067889e0609f248ab2de5718a328a 474 Pfam PF05954 Phage late control gene D protein (GPD) 67 167 1.0E-10 T 29-03-2018 A616_RS24540 3ba067889e0609f248ab2de5718a328a 474 Gene3D G3DSA:3.55.50.10 100 179 3.3E-11 T 29-03-2018 A616_RS24540 3ba067889e0609f248ab2de5718a328a 474 SUPERFAMILY SSF69279 11 173 2.17E-24 T 29-03-2018 A616_RS24210 c3e8780c8ac15e47b6f09aa3b80b0872 524 PIRSF PIRSF005690 28 523 7.4E-179 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS24210 c3e8780c8ac15e47b6f09aa3b80b0872 524 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 42 509 1.2E-185 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS20315 33ac67ceee78a4570ea30fe04b14ba66 262 Pfam PF06182 ABC-2 family transporter protein 33 261 7.3E-39 T 29-03-2018 IPR010390 Protein of unknown function DUF990 A616_RS15080 3fc70f1ea31dcdd9045f0d0700febe02 172 SUPERFAMILY SSF55729 8 155 2.13E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS15080 3fc70f1ea31dcdd9045f0d0700febe02 172 Gene3D G3DSA:3.40.630.30 3 172 1.4E-26 T 29-03-2018 A616_RS15080 3fc70f1ea31dcdd9045f0d0700febe02 172 Pfam PF00583 Acetyltransferase (GNAT) family 40 150 4.3E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS31690 f2211eda50918dd1e892dfeee35803a4 182 Gene3D G3DSA:3.40.50.360 1 182 1.6E-27 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS31690 f2211eda50918dd1e892dfeee35803a4 182 SUPERFAMILY SSF52218 7 153 1.95E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS31690 f2211eda50918dd1e892dfeee35803a4 182 Pfam PF03358 NADPH-dependent FMN reductase 7 140 2.5E-30 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A616_RS12670 52c401db047707a0a23a6adafdbefe01 310 Gene3D G3DSA:3.40.710.10 1 310 1.2E-127 T 29-03-2018 A616_RS12670 52c401db047707a0a23a6adafdbefe01 310 Pfam PF04960 Glutaminase 24 310 2.3E-120 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS12670 52c401db047707a0a23a6adafdbefe01 310 TIGRFAM TIGR03814 Gln_ase: glutaminase A 10 310 3.5E-125 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS12670 52c401db047707a0a23a6adafdbefe01 310 Hamap MF_00313 Glutaminase [glsA]. 6 310 47.091 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS12670 52c401db047707a0a23a6adafdbefe01 310 SUPERFAMILY SSF56601 8 310 8.25E-118 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS19650 c2a0bb8339c78f5042b2e69790c7b193 259 Pfam PF11868 Protein of unknown function (DUF3388) 73 251 2.3E-91 T 29-03-2018 IPR024514 Domain of unknown function DUF3388 A616_RS19650 c2a0bb8339c78f5042b2e69790c7b193 259 PIRSF PIRSF021288 1 258 1.8E-126 T 29-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain A616_RS19650 c2a0bb8339c78f5042b2e69790c7b193 259 SUPERFAMILY SSF55021 6 76 4.58E-9 T 29-03-2018 A616_RS19650 c2a0bb8339c78f5042b2e69790c7b193 259 Gene3D G3DSA:3.30.70.260 1 76 3.4E-6 T 29-03-2018 A616_RS31930 b9b974d90ff17248cc2bc87064e54aff 128 SUPERFAMILY SSF54593 6 123 3.76E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS31930 b9b974d90ff17248cc2bc87064e54aff 128 ProSitePatterns PS00934 Glyoxalase I signature 1. 11 32 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A616_RS31930 b9b974d90ff17248cc2bc87064e54aff 128 Gene3D G3DSA:3.10.180.10 4 127 2.9E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS31930 b9b974d90ff17248cc2bc87064e54aff 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 95 4.2E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS29305 5678c9f013ddd64bad543118229a4dd6 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 362 9.5E-103 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A616_RS29305 5678c9f013ddd64bad543118229a4dd6 385 Gene3D G3DSA:1.20.1090.10 182 385 3.8E-46 T 29-03-2018 A616_RS29305 5678c9f013ddd64bad543118229a4dd6 385 SUPERFAMILY SSF56796 2 382 1.7E-110 T 29-03-2018 A616_RS29305 5678c9f013ddd64bad543118229a4dd6 385 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A616_RS29305 5678c9f013ddd64bad543118229a4dd6 385 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 262 282 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A616_RS29305 5678c9f013ddd64bad543118229a4dd6 385 Gene3D G3DSA:3.40.50.1970 9 181 1.1E-46 T 29-03-2018 A616_RS31765 688870e27a57cc3408d82518c7498ef5 218 Pfam PF04854 Protein of unknown function, DUF624 25 95 8.8E-13 T 29-03-2018 IPR006938 Protein of unknown function DUF624 A616_RS19500 e94760b65781bce191fb01df7f9a4479 261 Pfam PF04445 Putative SAM-dependent methyltransferase 74 232 6.3E-18 T 29-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 A616_RS19500 e94760b65781bce191fb01df7f9a4479 261 Gene3D G3DSA:3.40.50.150 68 249 3.0E-22 T 29-03-2018 A616_RS19500 e94760b65781bce191fb01df7f9a4479 261 SUPERFAMILY SSF53335 2 241 9.16E-52 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS29765 d5a665d8e953b13fea9c12b6d5f15e52 366 Pfam PF00953 Glycosyl transferase family 4 73 234 5.8E-43 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS29765 d5a665d8e953b13fea9c12b6d5f15e52 366 ProSitePatterns PS01348 MraY family signature 2. 154 165 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS23105 ec099b91f95f7e5edb1b69d278f345a4 237 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 65 236 1.0E-79 T 29-03-2018 IPR018655 Protein of unknown function DUF2086 A616_RS23105 ec099b91f95f7e5edb1b69d278f345a4 237 Gene3D G3DSA:2.60.120.620 15 237 6.9E-22 T 29-03-2018 A616_RS02110 bfceb73a543b0278be44a45ceac2ae02 321 Pfam PF13145 PPIC-type PPIASE domain 143 266 1.4E-10 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 A616_RS02110 bfceb73a543b0278be44a45ceac2ae02 321 Gene3D G3DSA:3.10.50.40 155 280 2.2E-7 T 29-03-2018 A616_RS02110 bfceb73a543b0278be44a45ceac2ae02 321 SUPERFAMILY SSF109998 63 177 1.08E-10 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS00210 26932019e697a9a56f499236f5a2e973 486 SMART SM00116 98 146 4.9E-9 T 29-03-2018 IPR000644 CBS domain A616_RS00210 26932019e697a9a56f499236f5a2e973 486 SMART SM00116 159 207 2.5E-7 T 29-03-2018 IPR000644 CBS domain A616_RS00210 26932019e697a9a56f499236f5a2e973 486 SMART SM01240 9 472 0.0 T 29-03-2018 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 Gene3D G3DSA:3.20.20.70 2 481 6.2E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 472 1.1E-165 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 PIRSF PIRSF000130 1 486 2.2E-212 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 485 85.365 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 296 308 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 SUPERFAMILY SSF54631 67 207 3.41E-31 T 29-03-2018 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 Pfam PF00571 CBS domain 151 207 3.0E-7 T 29-03-2018 IPR000644 CBS domain A616_RS00210 26932019e697a9a56f499236f5a2e973 486 Pfam PF00571 CBS domain 97 142 1.1E-8 T 29-03-2018 IPR000644 CBS domain A616_RS00210 26932019e697a9a56f499236f5a2e973 486 SUPERFAMILY SSF51412 5 92 2.62E-127 T 29-03-2018 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 SUPERFAMILY SSF51412 218 476 2.62E-127 T 29-03-2018 A616_RS00210 26932019e697a9a56f499236f5a2e973 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 452 1.4E-194 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A616_RS03515 603450e31949e86144b9e2fa8cb12db9 265 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 53 181 3.9E-31 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A616_RS03515 603450e31949e86144b9e2fa8cb12db9 265 SUPERFAMILY SSF55166 49 189 8.11E-27 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS03515 603450e31949e86144b9e2fa8cb12db9 265 Gene3D G3DSA:3.30.1380.10 38 179 2.7E-28 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS04015 e31a3b2dba1a1860b9f0873ebc3c4f94 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 3.2E-25 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A616_RS04015 e31a3b2dba1a1860b9f0873ebc3c4f94 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 2.2E-31 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A616_RS04015 e31a3b2dba1a1860b9f0873ebc3c4f94 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 26.677 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A616_RS04015 e31a3b2dba1a1860b9f0873ebc3c4f94 96 SUPERFAMILY SSF141000 4 94 6.15E-34 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 A616_RS02210 97803a9bc4568b912668608fa9e911f9 308 Pfam PF04227 Indigoidine synthase A like protein 10 299 7.7E-137 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A616_RS02210 97803a9bc4568b912668608fa9e911f9 308 Gene3D G3DSA:3.40.1790.10 1 303 4.6E-144 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A616_RS02210 97803a9bc4568b912668608fa9e911f9 308 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 302 45.188 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A616_RS02210 97803a9bc4568b912668608fa9e911f9 308 SUPERFAMILY SSF110581 3 301 1.96E-120 T 29-03-2018 A616_RS31360 67c87bc87285435b0ea9035c5e6e29a4 295 SUPERFAMILY SSF160964 11 41 1.57E-5 T 29-03-2018 A616_RS31360 67c87bc87285435b0ea9035c5e6e29a4 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 284 1.1E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31360 67c87bc87285435b0ea9035c5e6e29a4 295 Gene3D G3DSA:1.20.58.370 5 43 3.2E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS31360 67c87bc87285435b0ea9035c5e6e29a4 295 SUPERFAMILY SSF161098 57 281 1.31E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31360 67c87bc87285435b0ea9035c5e6e29a4 295 Gene3D G3DSA:1.10.3720.10 63 293 4.5E-47 T 29-03-2018 A616_RS30090 59586e381bf46a871beff58b256105c8 427 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 43.463 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS30090 59586e381bf46a871beff58b256105c8 427 Gene3D G3DSA:3.65.10.10 1 87 2.5E-15 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS30090 59586e381bf46a871beff58b256105c8 427 SUPERFAMILY SSF55205 1 417 3.27E-140 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A616_RS30090 59586e381bf46a871beff58b256105c8 427 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 1.0E-167 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS30090 59586e381bf46a871beff58b256105c8 427 Gene3D G3DSA:3.65.10.10 88 223 7.6E-30 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS30090 59586e381bf46a871beff58b256105c8 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 2.0E-94 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS30090 59586e381bf46a871beff58b256105c8 427 Gene3D G3DSA:3.65.10.10 224 419 1.2E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS02685 38c5f0f877b4d4b667da709d815e0e19 386 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 206 383 2.5E-28 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS02685 38c5f0f877b4d4b667da709d815e0e19 386 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 17 385 2.1E-76 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS08945 afcba5502f6be565e98e09cdb63308d0 237 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 38 227 1.5E-42 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A616_RS08945 afcba5502f6be565e98e09cdb63308d0 237 Pfam PF04973 Nicotinamide mononucleotide transporter 38 224 1.8E-45 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 A616_RS08780 d1f1f60bb0c2573991a48007c0e11e27 278 SMART SM00342 187 271 1.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08780 d1f1f60bb0c2573991a48007c0e11e27 278 SUPERFAMILY SSF46689 234 270 2.2E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS08780 d1f1f60bb0c2573991a48007c0e11e27 278 Gene3D G3DSA:1.10.10.60 168 226 1.5E-9 T 29-03-2018 A616_RS08780 d1f1f60bb0c2573991a48007c0e11e27 278 Gene3D G3DSA:1.10.10.60 227 278 1.9E-6 T 29-03-2018 A616_RS08780 d1f1f60bb0c2573991a48007c0e11e27 278 Pfam PF12833 Helix-turn-helix domain 193 269 1.1E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08780 d1f1f60bb0c2573991a48007c0e11e27 278 SUPERFAMILY SSF46689 176 218 6.72E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS04590 c25a96506d6772a94703e25d8c37ae9d 134 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 128 3.2E-63 T 29-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 A616_RS04590 c25a96506d6772a94703e25d8c37ae9d 134 SMART SM00226 5 132 1.0E-54 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS04590 c25a96506d6772a94703e25d8c37ae9d 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 127 4.7E-24 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS04590 c25a96506d6772a94703e25d8c37ae9d 134 Hamap MF_01624 Protein ArsC [arsC]. 2 132 43.79 T 29-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 A616_RS04590 c25a96506d6772a94703e25d8c37ae9d 134 Gene3D G3DSA:3.40.50.2300 1 132 9.0E-42 T 29-03-2018 A616_RS04590 c25a96506d6772a94703e25d8c37ae9d 134 SUPERFAMILY SSF52788 4 128 4.19E-45 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A616_RS22170 48b1ad4c1aed70d4a9f5fdf92afbe1a3 234 Gene3D G3DSA:3.40.50.1820 1 234 1.2E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS22170 48b1ad4c1aed70d4a9f5fdf92afbe1a3 234 Pfam PF00756 Putative esterase 10 231 2.6E-40 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A616_RS22170 48b1ad4c1aed70d4a9f5fdf92afbe1a3 234 SUPERFAMILY SSF53474 4 233 7.41E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24345 6a3df2d52bb9e7660f498dab6535d449 491 PIRSF PIRSF005690 1 484 1.5E-139 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS24345 6a3df2d52bb9e7660f498dab6535d449 491 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 24 470 3.7E-150 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS09330 f9d1c09a48bc46104ead14e9e0998d6d 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 443 3.3E-105 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS09330 f9d1c09a48bc46104ead14e9e0998d6d 524 PIRSF PIRSF002741 2 523 4.8E-137 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS09330 f9d1c09a48bc46104ead14e9e0998d6d 524 Gene3D G3DSA:3.10.105.10 300 494 3.2E-57 T 29-03-2018 A616_RS09330 f9d1c09a48bc46104ead14e9e0998d6d 524 Gene3D G3DSA:3.40.190.10 167 299 3.0E-47 T 29-03-2018 A616_RS09330 f9d1c09a48bc46104ead14e9e0998d6d 524 SUPERFAMILY SSF53850 43 523 3.98E-152 T 29-03-2018 A616_RS09330 f9d1c09a48bc46104ead14e9e0998d6d 524 Gene3D G3DSA:3.90.76.10 65 166 2.9E-34 T 29-03-2018 A616_RS29120 a4ff7bd06088ac2ed1eadfcceff521f4 61 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 1.0E-7 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS29120 a4ff7bd06088ac2ed1eadfcceff521f4 61 Pfam PF08141 Small acid-soluble spore protein H family 1 58 1.4E-22 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS29120 a4ff7bd06088ac2ed1eadfcceff521f4 61 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 8.2E-19 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS29120 a4ff7bd06088ac2ed1eadfcceff521f4 61 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 15.427 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 A616_RS29435 d985c84c37143efdf858df3a04173b6a 269 Pfam PF01618 MotA/TolQ/ExbB proton channel family 104 213 5.0E-17 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A616_RS02475 0e7d755b29d7ab9db614c2d563ac567b 197 Gene3D G3DSA:1.10.10.10 2 181 1.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02475 0e7d755b29d7ab9db614c2d563ac567b 197 Pfam PF12840 Helix-turn-helix domain 15 71 2.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02475 0e7d755b29d7ab9db614c2d563ac567b 197 SUPERFAMILY SSF46785 14 82 4.28E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22285 c71b53bfe53afc40dc6c8ce6d94f2062 198 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 186 23.051 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A616_RS22285 c71b53bfe53afc40dc6c8ce6d94f2062 198 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 183 5.3E-41 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A616_RS22285 c71b53bfe53afc40dc6c8ce6d94f2062 198 SUPERFAMILY SSF55144 1 186 8.55E-42 T 29-03-2018 IPR009097 Cyclic phosphodiesterase A616_RS22285 c71b53bfe53afc40dc6c8ce6d94f2062 198 Pfam PF02834 LigT like Phosphoesterase 114 177 4.3E-5 T 29-03-2018 IPR014051 Phosphoesterase, HXTX A616_RS22285 c71b53bfe53afc40dc6c8ce6d94f2062 198 Pfam PF02834 LigT like Phosphoesterase 7 91 4.5E-16 T 29-03-2018 IPR014051 Phosphoesterase, HXTX A616_RS22285 c71b53bfe53afc40dc6c8ce6d94f2062 198 Gene3D G3DSA:3.90.1140.10 1 196 2.9E-34 T 29-03-2018 A616_RS00425 a9d4f387bb23e8a66c1ba298b5b857d7 193 Pfam PF11579 Protein of unknown function (DUF3238) 1 172 8.0E-19 T 29-03-2018 IPR021631 Protein of unknown function DUF3238 A616_RS06160 4574e8a36f854edd3bfb4d916e9761b6 518 Gene3D G3DSA:3.40.50.1390 5 178 3.5E-30 T 29-03-2018 A616_RS06160 4574e8a36f854edd3bfb4d916e9761b6 518 Pfam PF00239 Resolvase, N terminal domain 11 167 1.4E-19 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS06160 4574e8a36f854edd3bfb4d916e9761b6 518 Pfam PF13408 Recombinase zinc beta ribbon domain 314 366 1.2E-6 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain A616_RS06160 4574e8a36f854edd3bfb4d916e9761b6 518 SMART SM00857 10 168 1.6E-22 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS06160 4574e8a36f854edd3bfb4d916e9761b6 518 SUPERFAMILY SSF53041 10 166 5.89E-19 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A616_RS06160 4574e8a36f854edd3bfb4d916e9761b6 518 Pfam PF07508 Recombinase 189 300 1.1E-22 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A616_RS20020 d0f674b957ea12cd672e5951f739163f 148 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 144 2.8E-23 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A616_RS20020 d0f674b957ea12cd672e5951f739163f 148 Pfam PF02050 Flagellar FliJ protein 20 143 4.1E-16 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A616_RS11455 6c44e75d091229ec7fbf09c6ba8e9f26 380 Pfam PF04055 Radical SAM superfamily 8 180 2.0E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS11455 6c44e75d091229ec7fbf09c6ba8e9f26 380 Gene3D G3DSA:3.20.20.70 4 314 1.4E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS11455 6c44e75d091229ec7fbf09c6ba8e9f26 380 SMART SM00729 3 226 7.7E-57 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS11455 6c44e75d091229ec7fbf09c6ba8e9f26 380 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 5 367 3.3E-115 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 A616_RS11455 6c44e75d091229ec7fbf09c6ba8e9f26 380 Pfam PF06969 HemN C-terminal domain 305 368 4.4E-18 T 29-03-2018 IPR010723 HemN, C-terminal A616_RS11455 6c44e75d091229ec7fbf09c6ba8e9f26 380 SUPERFAMILY SSF102114 4 379 2.62E-117 T 29-03-2018 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 Gene3D G3DSA:3.40.190.10 88 173 3.6E-20 T 29-03-2018 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 Gene3D G3DSA:3.40.190.10 174 261 1.3E-20 T 29-03-2018 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 Pfam PF03466 LysR substrate binding domain 88 288 1.5E-46 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 SUPERFAMILY SSF53850 89 293 2.1E-44 T 29-03-2018 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.5E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 SUPERFAMILY SSF46785 1 87 2.87E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23830 eeb0b02b669c974c01ed1c911fb4c97d 307 Gene3D G3DSA:1.10.10.10 1 83 6.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 Pfam PF00202 Aminotransferase class-III 37 442 3.0E-129 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 258 295 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 Gene3D G3DSA:3.90.1150.10 329 444 4.8E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 PIRSF PIRSF000521 1 143 4.8E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 PIRSF PIRSF000521 138 445 9.9E-47 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 SUPERFAMILY SSF53383 36 443 2.59E-134 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 25 443 8.8E-179 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 Gene3D G3DSA:3.90.1150.10 26 193 4.3E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS31465 a2ae7fa52d4acd6fba90351686158e99 449 Gene3D G3DSA:3.40.640.10 194 328 3.2E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS19710 22551a871979854723c1220c048c18f3 76 Pfam PF14035 YlzJ-like protein 3 68 2.4E-23 T 29-03-2018 IPR025619 YlzJ-like protein A616_RS25660 87728b03fa2f7ec7f3e7faf8cceee1cc 138 Pfam PF13508 Acetyltransferase (GNAT) domain 50 126 2.5E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25660 87728b03fa2f7ec7f3e7faf8cceee1cc 138 SUPERFAMILY SSF55729 20 131 5.32E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25660 87728b03fa2f7ec7f3e7faf8cceee1cc 138 Gene3D G3DSA:3.40.630.30 2 135 1.1E-16 T 29-03-2018 A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 Pfam PF00027 Cyclic nucleotide-binding domain 37 120 6.6E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 Pfam PF13545 Crp-like helix-turn-helix domain 154 223 1.5E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 SUPERFAMILY SSF46785 151 227 7.14E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 SMART SM00100 13 133 2.5E-4 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 Gene3D G3DSA:2.60.120.10 13 150 1.5E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 Gene3D G3DSA:1.10.10.10 151 232 4.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25485 7aa9dc0bbc6fe97f6eb18da6e8ca61d3 232 SUPERFAMILY SSF51206 21 139 7.59E-24 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS18205 cac21fca6d8edc56d72cdf9ce15e7d7f 170 SUPERFAMILY SSF55021 93 168 4.04E-14 T 29-03-2018 A616_RS18205 cac21fca6d8edc56d72cdf9ce15e7d7f 170 Pfam PF01842 ACT domain 101 161 6.9E-9 T 29-03-2018 IPR002912 ACT domain A616_RS18205 cac21fca6d8edc56d72cdf9ce15e7d7f 170 Gene3D G3DSA:3.30.70.260 90 169 4.7E-13 T 29-03-2018 A616_RS08220 fdd88260bd57387ca9230b16b546d303 435 Pfam PF00296 Luciferase-like monooxygenase 27 386 2.8E-56 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS08220 fdd88260bd57387ca9230b16b546d303 435 Gene3D G3DSA:3.20.20.30 1 435 8.1E-89 T 29-03-2018 A616_RS08220 fdd88260bd57387ca9230b16b546d303 435 SUPERFAMILY SSF51679 5 433 6.02E-109 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS08220 fdd88260bd57387ca9230b16b546d303 435 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 16 431 1.0E-121 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A616_RS08220 fdd88260bd57387ca9230b16b546d303 435 PIRSF PIRSF000337 3 435 1.9E-138 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 SUPERFAMILY SSF88659 123 176 8.04E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 Pfam PF08281 Sigma-70, region 4 120 169 5.9E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 175 1.3E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 Gene3D G3DSA:1.10.1740.10 1 114 1.5E-23 T 29-03-2018 A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 Pfam PF04542 Sigma-70 region 2 24 93 2.7E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 Gene3D G3DSA:1.10.10.10 115 181 1.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10995 998ee9b848205c8b2822ae8a8eab441e 181 SUPERFAMILY SSF88946 4 109 3.3E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09915 5775781ff475fa88bd07ed98d0036ad3 319 Gene3D G3DSA:1.20.58.370 22 66 4.9E-9 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS09915 5775781ff475fa88bd07ed98d0036ad3 319 SUPERFAMILY SSF160964 30 78 6.93E-8 T 29-03-2018 A616_RS09915 5775781ff475fa88bd07ed98d0036ad3 319 Gene3D G3DSA:1.10.3720.10 84 317 1.7E-52 T 29-03-2018 A616_RS09915 5775781ff475fa88bd07ed98d0036ad3 319 SUPERFAMILY SSF161098 76 307 5.1E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09915 5775781ff475fa88bd07ed98d0036ad3 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 314 2.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS10440 40ebeda9a1d0ad1e00ccc112b564cade 108 Gene3D G3DSA:3.30.750.24 1 105 9.2E-15 T 29-03-2018 IPR002645 STAS domain A616_RS10440 40ebeda9a1d0ad1e00ccc112b564cade 108 Pfam PF01740 STAS domain 5 96 9.2E-11 T 29-03-2018 IPR002645 STAS domain A616_RS10440 40ebeda9a1d0ad1e00ccc112b564cade 108 SUPERFAMILY SSF52091 1 98 3.34E-18 T 29-03-2018 IPR002645 STAS domain A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 Gene3D G3DSA:1.10.10.10 161 228 9.3E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 SUPERFAMILY SSF52172 3 171 2.85E-34 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 Gene3D G3DSA:3.40.50.2300 3 150 4.0E-30 T 29-03-2018 A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 Pfam PF00072 Response regulator receiver domain 6 117 1.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 SMART SM00448 4 117 1.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 Pfam PF08279 HTH domain 165 203 5.7E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS18690 9f92787a4989a0e9a1fee8f334f98436 229 PIRSF PIRSF006171 2 229 2.0E-80 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 Pfam PF01497 Periplasmic binding protein 278 432 8.0E-10 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 225 267 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 SUPERFAMILY SSF46689 225 275 1.34E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 SUPERFAMILY SSF46689 172 222 4.36E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 Gene3D G3DSA:1.10.10.60 162 221 3.4E-11 T 29-03-2018 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 SMART SM00342 188 271 8.4E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 Gene3D G3DSA:1.10.10.60 222 273 2.5E-13 T 29-03-2018 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 Pfam PF12833 Helix-turn-helix domain 194 272 8.7E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 SUPERFAMILY SSF53807 276 512 3.45E-26 T 29-03-2018 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 Gene3D G3DSA:3.40.50.1980 274 367 7.3E-9 T 29-03-2018 A616_RS21875 b9a5004f545758f1e3e83be21a1feaa8 539 Gene3D G3DSA:3.40.50.1980 368 513 3.2E-12 T 29-03-2018 A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 Gene3D G3DSA:1.10.1740.10 9 79 2.4E-19 T 29-03-2018 A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 166 2.0E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 Pfam PF04545 Sigma-70, region 4 118 164 2.2E-10 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 SUPERFAMILY SSF88659 99 169 4.3E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 Gene3D G3DSA:1.10.10.10 80 170 1.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 SUPERFAMILY SSF88946 13 88 3.92E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS03225 9754b3adca75616cae3d8ab8019d2bcf 171 Pfam PF04542 Sigma-70 region 2 15 81 1.5E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS29965 8e553bf8723bb23a92655124fe04a711 399 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 29 385 6.5E-144 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A616_RS29965 8e553bf8723bb23a92655124fe04a711 399 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A616_RS29965 8e553bf8723bb23a92655124fe04a711 399 Pfam PF00155 Aminotransferase class I and II 44 385 2.8E-65 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A616_RS29965 8e553bf8723bb23a92655124fe04a711 399 SUPERFAMILY SSF53383 3 392 1.2E-108 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS29965 8e553bf8723bb23a92655124fe04a711 399 Gene3D G3DSA:3.40.640.10 51 287 1.6E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS29965 8e553bf8723bb23a92655124fe04a711 399 Gene3D G3DSA:3.90.1150.10 288 397 1.4E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS23705 2b456d095c7e197317fe3c3130f300be 152 Gene3D G3DSA:3.90.79.10 2 143 5.1E-24 T 29-03-2018 A616_RS23705 2b456d095c7e197317fe3c3130f300be 152 SUPERFAMILY SSF55811 9 140 2.17E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS23705 2b456d095c7e197317fe3c3130f300be 152 Pfam PF00293 NUDIX domain 10 121 4.6E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS23705 2b456d095c7e197317fe3c3130f300be 152 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS13050 4968c9081eeb3bd5e3d07c5c0eb2147c 320 Gene3D G3DSA:3.40.50.300 51 315 8.4E-9 T 29-03-2018 A616_RS13050 4968c9081eeb3bd5e3d07c5c0eb2147c 320 SMART SM00382 148 286 1.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS13050 4968c9081eeb3bd5e3d07c5c0eb2147c 320 SUPERFAMILY SSF52540 63 275 1.45E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS13050 4968c9081eeb3bd5e3d07c5c0eb2147c 320 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 305 1.5E-118 T 29-03-2018 IPR014217 Sporulation stage III, protein AA A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 Gene3D G3DSA:3.30.1330.90 20 144 1.2E-24 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 9.1E-75 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 PIRSF PIRSF036692 1 220 2.7E-95 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 SUPERFAMILY SSF143548 19 137 8.24E-29 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 SUPERFAMILY SSF55021 137 218 4.58E-16 T 29-03-2018 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 Pfam PF03315 Serine dehydratase beta chain 5 77 8.9E-10 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 Gene3D G3DSA:3.30.70.260 147 221 3.9E-17 T 29-03-2018 A616_RS20680 210cf6aee0f50bd2e9b08be3354a258b 221 Pfam PF01842 ACT domain 148 210 1.9E-12 T 29-03-2018 IPR002912 ACT domain A616_RS22070 e5dcdee88487766131c879ff0be01193 281 SUPERFAMILY SSF56214 153 260 1.57E-9 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS22070 e5dcdee88487766131c879ff0be01193 281 Gene3D G3DSA:3.90.470.20 163 268 5.6E-7 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS22070 e5dcdee88487766131c879ff0be01193 281 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 154 253 3.4E-10 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS22070 e5dcdee88487766131c879ff0be01193 281 SUPERFAMILY SSF56214 56 144 8.76E-10 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS22070 e5dcdee88487766131c879ff0be01193 281 Gene3D G3DSA:3.90.470.20 59 162 4.5E-14 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A616_RS25600 d3558b359438385db3de7a0c286b7dbf 93 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 4 85 1.7E-16 T 29-03-2018 IPR016772 Uncharacterised conserved protein UCP020408 A616_RS32050 27f667ec172d0e5a06ab9202d556ecc1 327 SUPERFAMILY SSF53807 53 324 2.55E-51 T 29-03-2018 A616_RS32050 27f667ec172d0e5a06ab9202d556ecc1 327 Gene3D G3DSA:3.40.50.1980 166 327 1.1E-28 T 29-03-2018 A616_RS32050 27f667ec172d0e5a06ab9202d556ecc1 327 Gene3D G3DSA:3.40.50.1980 49 165 1.6E-24 T 29-03-2018 A616_RS32050 27f667ec172d0e5a06ab9202d556ecc1 327 Pfam PF01497 Periplasmic binding protein 70 304 2.1E-24 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS06655 7add1ee7e93317925c0ce10c67b5f32e 301 SUPERFAMILY SSF103481 42 141 5.89E-15 T 29-03-2018 A616_RS06655 7add1ee7e93317925c0ce10c67b5f32e 301 Pfam PF00892 EamA-like transporter family 9 139 2.9E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS06655 7add1ee7e93317925c0ce10c67b5f32e 301 Pfam PF00892 EamA-like transporter family 151 285 1.4E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS06655 7add1ee7e93317925c0ce10c67b5f32e 301 SUPERFAMILY SSF103481 202 289 1.05E-10 T 29-03-2018 A616_RS08790 67b254fce700de727050734a6d844425 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 122 3.2E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS08790 67b254fce700de727050734a6d844425 125 SUPERFAMILY SSF54593 4 124 2.15E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS08790 67b254fce700de727050734a6d844425 125 Gene3D G3DSA:3.10.180.10 1 125 5.7E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS13765 ae97a1302d8eb2c82af1fe4912fb409c 198 Gene3D G3DSA:3.40.50.1950 4 198 2.2E-51 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS13765 ae97a1302d8eb2c82af1fe4912fb409c 198 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 7 196 1.4E-60 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 A616_RS13765 ae97a1302d8eb2c82af1fe4912fb409c 198 SUPERFAMILY SSF52507 5 198 1.44E-57 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS13765 ae97a1302d8eb2c82af1fe4912fb409c 198 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 4 198 34.407 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 A616_RS13765 ae97a1302d8eb2c82af1fe4912fb409c 198 Pfam PF02441 Flavoprotein 5 177 7.9E-27 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS03345 48b75b1a6b428de323db8f0ec34a496c 139 SUPERFAMILY SSF52172 2 121 2.85E-35 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03345 48b75b1a6b428de323db8f0ec34a496c 139 Pfam PF00072 Response regulator receiver domain 4 114 2.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03345 48b75b1a6b428de323db8f0ec34a496c 139 SMART SM00448 2 114 5.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03345 48b75b1a6b428de323db8f0ec34a496c 139 Gene3D G3DSA:3.40.50.2300 2 137 2.7E-35 T 29-03-2018 A616_RS11370 f87e8ecaca461374434356babdebee95 724 SMART SM00939 459 708 2.0E-74 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A616_RS11370 f87e8ecaca461374434356babdebee95 724 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 471 707 1.3E-45 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 A616_RS11370 f87e8ecaca461374434356babdebee95 724 Gene3D G3DSA:3.40.50.1820 162 490 9.8E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS11370 f87e8ecaca461374434356babdebee95 724 SUPERFAMILY SSF49785 486 712 1.45E-51 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS11370 f87e8ecaca461374434356babdebee95 724 SUPERFAMILY SSF53474 163 495 8.78E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS11370 f87e8ecaca461374434356babdebee95 724 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 180 433 1.3E-58 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A616_RS11370 f87e8ecaca461374434356babdebee95 724 Gene3D G3DSA:2.60.120.260 491 712 5.4E-55 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS11370 f87e8ecaca461374434356babdebee95 724 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 176 712 2.1E-121 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 A616_RS07550 9fe1a761fce3aa1ca2b697913ca171e6 507 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 3 485 1.4E-201 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A616_RS07550 9fe1a761fce3aa1ca2b697913ca171e6 507 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 40 485 8.9E-167 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A616_RS07550 9fe1a761fce3aa1ca2b697913ca171e6 507 ProSitePatterns PS01303 BCCT family of transporters signature. 303 312 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 318 336 1.3E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.3E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 Gene3D G3DSA:3.50.50.60 1 156 2.6E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 Gene3D G3DSA:3.40.50.720 157 358 2.6E-13 T 29-03-2018 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 330 8.9E-17 T 29-03-2018 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 8.9E-17 T 29-03-2018 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 8.9E-17 T 29-03-2018 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 8.9E-17 T 29-03-2018 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 342 2.7E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS25250 bbed212cdf0a7b8d518ffae42f7da814 401 SUPERFAMILY SSF51905 1 352 1.0E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 Pfam PF13602 Zinc-binding dehydrogenase 187 314 8.0E-21 T 29-03-2018 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 2.0E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 Gene3D G3DSA:3.40.50.720 148 249 3.0E-18 T 29-03-2018 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 SUPERFAMILY SSF51735 117 234 4.29E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 SMART SM00829 10 314 4.5E-20 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 Gene3D G3DSA:3.90.180.10 250 317 0.02 T 29-03-2018 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 Gene3D G3DSA:3.90.180.10 1 147 1.1E-44 T 29-03-2018 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 A616_RS14585 b0b112593b2fd8168d35172e3ece40fc 317 SUPERFAMILY SSF50129 2 150 1.98E-36 T 29-03-2018 IPR011032 GroES-like A616_RS13100 b26a4e6e51eb6b2dd3077fb263273e59 138 Pfam PF03780 Asp23 family, cell envelope-related function 13 117 7.0E-38 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 A616_RS14465 b289cc67edca54a46377b526e27475d6 184 Gene3D G3DSA:1.20.1260.10 1 158 3.6E-22 T 29-03-2018 IPR012347 Ferritin-related A616_RS14465 b289cc67edca54a46377b526e27475d6 184 Pfam PF07875 Coat F domain 100 162 3.3E-15 T 29-03-2018 IPR012851 Spore coat protein CotF-like A616_RS15015 0fe5c202a63ea879685ad1cdd05490f5 326 SUPERFAMILY SSF53807 50 303 1.65E-48 T 29-03-2018 A616_RS15015 0fe5c202a63ea879685ad1cdd05490f5 326 Gene3D G3DSA:3.40.50.1980 168 322 1.9E-29 T 29-03-2018 A616_RS15015 0fe5c202a63ea879685ad1cdd05490f5 326 Pfam PF01497 Periplasmic binding protein 82 298 2.0E-31 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS15015 0fe5c202a63ea879685ad1cdd05490f5 326 Gene3D G3DSA:3.40.50.1980 41 167 4.4E-21 T 29-03-2018 A616_RS27575 a039aa98f30bd26513affeeae1fac71b 116 Pfam PF10710 Protein of unknown function (DUF2512) 4 109 7.0E-6 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 A616_RS29485 b745be2f2b40ecd7607fec468bc73e97 332 Gene3D G3DSA:3.40.630.30 8 146 3.9E-5 T 29-03-2018 A616_RS29485 b745be2f2b40ecd7607fec468bc73e97 332 Gene3D G3DSA:3.40.630.30 147 294 7.8E-19 T 29-03-2018 A616_RS29485 b745be2f2b40ecd7607fec468bc73e97 332 SUPERFAMILY SSF55729 149 295 7.42E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS02170 e45d46a17f4300d3ca7c3f54ace065bf 444 PIRSF PIRSF006446 1 444 6.7E-109 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A616_RS02170 e45d46a17f4300d3ca7c3f54ace065bf 444 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 2 426 5.2E-119 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 Gene3D G3DSA:1.10.10.10 1 83 2.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.7E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 Gene3D G3DSA:3.40.190.10 173 258 1.0E-15 T 29-03-2018 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 Pfam PF03466 LysR substrate binding domain 89 283 5.8E-33 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 Gene3D G3DSA:3.40.190.10 88 172 3.4E-14 T 29-03-2018 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 SUPERFAMILY SSF53850 90 290 1.71E-33 T 29-03-2018 A616_RS24845 ecc28a7db7cca5460883a7cfd50a03eb 299 SUPERFAMILY SSF46785 2 86 1.77E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS01795 eb2860e1b772f5dc07973e9e9aaea0d1 354 Pfam PF07993 Male sterility protein 5 240 8.0E-46 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 A616_RS01795 eb2860e1b772f5dc07973e9e9aaea0d1 354 SUPERFAMILY SSF51735 1 307 1.67E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS01795 eb2860e1b772f5dc07973e9e9aaea0d1 354 Gene3D G3DSA:3.40.50.720 2 331 4.3E-45 T 29-03-2018 A616_RS12825 c837a1bec1f993e07faa89d325d4ae3b 189 SUPERFAMILY SSF47240 1 186 6.21E-69 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS12825 c837a1bec1f993e07faa89d325d4ae3b 189 Gene3D G3DSA:1.20.1260.10 1 184 1.3E-54 T 29-03-2018 IPR012347 Ferritin-related A616_RS12825 c837a1bec1f993e07faa89d325d4ae3b 189 Pfam PF05067 Manganese containing catalase 1 184 1.3E-74 T 29-03-2018 IPR007760 Manganese catalase A616_RS15195 ba877605ad6b4a1adbf043719060160c 445 Gene3D G3DSA:3.90.1150.10 295 438 2.0E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS15195 ba877605ad6b4a1adbf043719060160c 445 PIRSF PIRSF000412 16 445 2.2E-104 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A616_RS15195 ba877605ad6b4a1adbf043719060160c 445 Gene3D G3DSA:3.40.640.10 62 294 5.0E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS15195 ba877605ad6b4a1adbf043719060160c 445 Pfam PF00464 Serine hydroxymethyltransferase 34 412 3.5E-52 T 29-03-2018 A616_RS15195 ba877605ad6b4a1adbf043719060160c 445 SUPERFAMILY SSF53383 35 442 3.85E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS22400 48342207e69a16b42a1cad9fcd483c9a 282 SUPERFAMILY SSF56281 6 265 3.67E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22400 48342207e69a16b42a1cad9fcd483c9a 282 Pfam PF00753 Metallo-beta-lactamase superfamily 56 221 4.7E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22400 48342207e69a16b42a1cad9fcd483c9a 282 Gene3D G3DSA:3.60.15.10 6 271 6.8E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS22400 48342207e69a16b42a1cad9fcd483c9a 282 SMART SM00849 52 259 2.2E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02220 b0ed43e01d5d985a4ec4f985a079e800 66 Gene3D G3DSA:3.30.70.100 1 66 2.1E-17 T 29-03-2018 A616_RS02220 b0ed43e01d5d985a4ec4f985a079e800 66 Pfam PF00403 Heavy-metal-associated domain 5 64 7.1E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS02220 b0ed43e01d5d985a4ec4f985a079e800 66 PRINTS PR00944 Copper ion binding protein signature 52 65 6.6E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A616_RS02220 b0ed43e01d5d985a4ec4f985a079e800 66 PRINTS PR00944 Copper ion binding protein signature 3 15 6.6E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A616_RS02220 b0ed43e01d5d985a4ec4f985a079e800 66 PRINTS PR00944 Copper ion binding protein signature 15 28 6.6E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 A616_RS02220 b0ed43e01d5d985a4ec4f985a079e800 66 SUPERFAMILY SSF55008 2 66 1.17E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A616_RS31755 1be259868e12bfe62df0a74c96c995a8 293 Gene3D G3DSA:3.30.200.20 2 82 1.6E-6 T 29-03-2018 A616_RS31755 1be259868e12bfe62df0a74c96c995a8 293 SUPERFAMILY SSF56112 3 269 6.97E-35 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS31755 1be259868e12bfe62df0a74c96c995a8 293 Gene3D G3DSA:3.90.1200.10 97 284 2.7E-18 T 29-03-2018 A616_RS31755 1be259868e12bfe62df0a74c96c995a8 293 Pfam PF01636 Phosphotransferase enzyme family 22 241 3.7E-16 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS12940 992dc9c45f804c9dee2cd4048e25fa1d 359 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 142 2.9E-33 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS12940 992dc9c45f804c9dee2cd4048e25fa1d 359 Gene3D G3DSA:3.40.50.2000 189 343 1.8E-26 T 29-03-2018 A616_RS12940 992dc9c45f804c9dee2cd4048e25fa1d 359 Gene3D G3DSA:3.40.50.2000 1 188 4.6E-33 T 29-03-2018 A616_RS12940 992dc9c45f804c9dee2cd4048e25fa1d 359 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 356 27.463 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A616_RS12940 992dc9c45f804c9dee2cd4048e25fa1d 359 SUPERFAMILY SSF53756 3 336 3.14E-90 T 29-03-2018 A616_RS12940 992dc9c45f804c9dee2cd4048e25fa1d 359 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 347 1.9E-32 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS06595 07a101a9adf991a69314d076bfa48438 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 217 6.9E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS06595 07a101a9adf991a69314d076bfa48438 219 SUPERFAMILY SSF161098 13 203 1.83E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS06595 07a101a9adf991a69314d076bfa48438 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 112 1.0E-23 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS06595 07a101a9adf991a69314d076bfa48438 219 Gene3D G3DSA:1.10.3720.10 4 219 2.3E-42 T 29-03-2018 A616_RS22215 b1d1e048b11879461e8f1b724e476e92 240 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 184 6.6E-32 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS10185 34f0b19083816454d45b36cfcc8dbced 313 SUPERFAMILY SSF161098 100 295 2.35E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS10185 34f0b19083816454d45b36cfcc8dbced 313 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 72 1.6E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS10185 34f0b19083816454d45b36cfcc8dbced 313 Gene3D G3DSA:1.10.3720.10 32 301 2.8E-43 T 29-03-2018 A616_RS10185 34f0b19083816454d45b36cfcc8dbced 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 312 3.2E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 Gene3D G3DSA:3.40.1010.10 4 129 4.5E-37 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 SUPERFAMILY SSF53790 4 252 1.96E-82 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 10 24 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 Gene3D G3DSA:3.30.950.10 130 261 3.9E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 219 1.0E-49 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 85 118 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS07380 da53f758bc46fc4ee6841b914f7f3f65 261 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 5 244 9.0E-97 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A616_RS25995 a605f410ae53c4abc52bf4075bc733ec 174 Pfam PF12867 DinB superfamily 12 150 1.3E-11 T 29-03-2018 IPR024775 DinB-like domain A616_RS25995 a605f410ae53c4abc52bf4075bc733ec 174 SUPERFAMILY SSF109854 1 154 7.48E-25 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS25995 a605f410ae53c4abc52bf4075bc733ec 174 Gene3D G3DSA:1.20.120.450 1 171 1.0E-22 T 29-03-2018 A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 420 2.9E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 SUPERFAMILY SSF55874 271 419 6.02E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 1.4E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 Gene3D G3DSA:3.30.565.10 175 421 1.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05230 b562ebedcc0a61ea537409b0dfa4db91 427 SMART SM00387 309 422 1.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS27095 a3a61d28a51c1d40eaa262ea9551fd7e 406 Gene3D G3DSA:1.20.1250.20 14 198 6.0E-24 T 29-03-2018 A616_RS27095 a3a61d28a51c1d40eaa262ea9551fd7e 406 Gene3D G3DSA:1.20.1250.20 200 405 1.0E-22 T 29-03-2018 A616_RS27095 a3a61d28a51c1d40eaa262ea9551fd7e 406 SUPERFAMILY SSF103473 18 390 5.89E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS27095 a3a61d28a51c1d40eaa262ea9551fd7e 406 Pfam PF12832 MFS_1 like family 18 372 6.8E-47 T 29-03-2018 IPR024989 Major facilitator superfamily associated domain A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 24 431 1.6E-136 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 Gene3D G3DSA:3.50.50.60 20 442 1.1E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 Pfam PF03486 HI0933-like protein 22 432 5.9E-140 T 29-03-2018 A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 23 45 4.2E-7 T 29-03-2018 A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 187 4.2E-7 T 29-03-2018 A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 SUPERFAMILY SSF51905 377 433 1.18E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 SUPERFAMILY SSF51905 21 213 1.18E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS22905 a76d5d7974ec4b260d6c7cea6972c47b 447 SUPERFAMILY SSF160996 212 380 1.83E-43 T 29-03-2018 A616_RS13035 19fc7718b77a48250da00d9e66ea20b6 273 Gene3D G3DSA:3.20.20.70 19 262 4.3E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS13035 19fc7718b77a48250da00d9e66ea20b6 273 Pfam PF02679 (2R)-phospho-3-sulfolactate synthase (ComA) 21 259 2.7E-79 T 29-03-2018 IPR003830 (2R)-phospho-3-sulpholactate synthase, ComA KEGG: 00680+4.4.1.19 A616_RS13035 19fc7718b77a48250da00d9e66ea20b6 273 SUPERFAMILY SSF102110 20 262 2.88E-75 T 29-03-2018 IPR003830 (2R)-phospho-3-sulpholactate synthase, ComA KEGG: 00680+4.4.1.19 A616_RS03980 ab9d8135231e11d62f414da1d82385dc 308 Gene3D G3DSA:2.130.10.10 65 294 4.6E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A616_RS03980 ab9d8135231e11d62f414da1d82385dc 308 Pfam PF14870 Photosynthesis system II assembly factor YCF48 63 240 4.4E-6 T 29-03-2018 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain A616_RS03980 ab9d8135231e11d62f414da1d82385dc 308 SUPERFAMILY SSF50952 156 307 2.35E-5 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A616_RS03980 ab9d8135231e11d62f414da1d82385dc 308 SUPERFAMILY SSF110296 69 217 4.58E-18 T 29-03-2018 A616_RS10085 a0a49a11320fe693da6f4571fd38ac7d 197 SUPERFAMILY SSF53335 14 167 7.4E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10085 a0a49a11320fe693da6f4571fd38ac7d 197 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 21 166 9.9E-28 T 29-03-2018 IPR006342 Methyltransferase FkbM A616_RS10085 a0a49a11320fe693da6f4571fd38ac7d 197 Gene3D G3DSA:3.40.50.150 7 197 5.7E-29 T 29-03-2018 A616_RS10085 a0a49a11320fe693da6f4571fd38ac7d 197 Pfam PF05050 Methyltransferase FkbM domain 23 186 1.1E-16 T 29-03-2018 IPR006342 Methyltransferase FkbM A616_RS08285 39b3298a45b7f37d17e4b3e2be62e16a 190 Pfam PF03551 Transcriptional regulator PadR-like family 12 88 8.1E-8 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS08285 39b3298a45b7f37d17e4b3e2be62e16a 190 Gene3D G3DSA:1.10.10.10 1 100 6.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08285 39b3298a45b7f37d17e4b3e2be62e16a 190 SUPERFAMILY SSF46785 7 144 2.58E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02780 35d001ad47725aace4bbd110a4304d91 257 SMART SM00382 35 228 2.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02780 35d001ad47725aace4bbd110a4304d91 257 Pfam PF00005 ABC transporter 26 181 5.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02780 35d001ad47725aace4bbd110a4304d91 257 Gene3D G3DSA:3.40.50.300 7 255 1.8E-58 T 29-03-2018 A616_RS02780 35d001ad47725aace4bbd110a4304d91 257 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02780 35d001ad47725aace4bbd110a4304d91 257 SUPERFAMILY SSF52540 7 244 1.29E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02780 35d001ad47725aace4bbd110a4304d91 257 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 11 257 1.2E-121 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 Gene3D G3DSA:1.10.10.10 144 242 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 SMART SM00448 1 113 2.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 Pfam PF03704 Bacterial transcriptional activator domain 259 371 5.8E-10 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 217 1.8E-5 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 SUPERFAMILY SSF48452 259 374 1.33E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 SMART SM01043 238 377 7.2E-16 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 SUPERFAMILY SSF52172 1 132 5.98E-30 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 Pfam PF00072 Response regulator receiver domain 4 112 7.9E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 Gene3D G3DSA:3.40.50.2300 1 137 9.5E-27 T 29-03-2018 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 Gene3D G3DSA:1.25.40.10 243 383 1.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS03395 4b47fdb09a39e3dfe5038e55eee90730 383 SUPERFAMILY SSF46894 136 219 2.61E-11 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 SMART SM00437 264 551 4.0E-80 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Gene3D G3DSA:3.40.50.140 3 154 2.9E-41 T 29-03-2018 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 301 316 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 SMART SM00493 3 126 2.5E-18 T 29-03-2018 IPR006171 TOPRIM domain A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Gene3D G3DSA:1.10.460.10 473 656 5.7E-30 T 29-03-2018 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 640 64.441 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Pfam PF01751 Toprim domain 5 134 2.0E-14 T 29-03-2018 IPR006171 TOPRIM domain A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 SMART SM00436 126 216 7.3E-40 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Pfam PF01131 DNA topoisomerase 152 585 9.7E-119 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 729 2.6E-256 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Gene3D G3DSA:2.70.20.10 350 472 1.4E-29 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 Gene3D G3DSA:1.10.460.10 159 341 6.4E-39 T 29-03-2018 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 SUPERFAMILY SSF56712 3 601 1.96E-174 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 1.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 389 405 1.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS27325 725cbefa6dff4692c2ef9692f3fbf8e6 732 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 307 316 1.2E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A616_RS01340 a0c0ee6db05e7c657ff0f1b078ea6dde 198 Pfam PF05175 Methyltransferase small domain 27 194 3.7E-49 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A616_RS01340 a0c0ee6db05e7c657ff0f1b078ea6dde 198 Gene3D G3DSA:3.40.50.150 12 198 1.1E-36 T 29-03-2018 A616_RS01340 a0c0ee6db05e7c657ff0f1b078ea6dde 198 SUPERFAMILY SSF53335 11 196 3.5E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS00250 bc3eb6afa4c43663d0d3971ec14b4743 365 Gene3D G3DSA:3.40.190.10 27 180 1.0E-7 T 29-03-2018 A616_RS00250 bc3eb6afa4c43663d0d3971ec14b4743 365 Gene3D G3DSA:3.40.190.10 181 360 2.3E-18 T 29-03-2018 A616_RS00250 bc3eb6afa4c43663d0d3971ec14b4743 365 Pfam PF13343 Bacterial extracellular solute-binding protein 102 323 4.0E-36 T 29-03-2018 A616_RS00250 bc3eb6afa4c43663d0d3971ec14b4743 365 SUPERFAMILY SSF53850 52 358 1.02E-47 T 29-03-2018 A616_RS31295 55c63d318d48ec45674032dda78d0e33 256 Pfam PF02389 Cornifin (SPRR) family 114 205 1.5E-8 T 29-03-2018 A616_RS31295 55c63d318d48ec45674032dda78d0e33 256 Pfam PF02389 Cornifin (SPRR) family 42 135 3.8E-9 T 29-03-2018 A616_RS26045 7d4e93d9b0e64c7ed8a440d3fe589d49 537 SUPERFAMILY SSF52279 367 530 1.7E-9 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A616_RS26045 7d4e93d9b0e64c7ed8a440d3fe589d49 537 Gene3D G3DSA:3.40.50.1700 350 532 2.2E-19 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A616_RS26045 7d4e93d9b0e64c7ed8a440d3fe589d49 537 Gene3D G3DSA:3.20.20.300 2 347 1.5E-95 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A616_RS26045 7d4e93d9b0e64c7ed8a440d3fe589d49 537 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 7 332 1.4E-95 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A616_RS26045 7d4e93d9b0e64c7ed8a440d3fe589d49 537 SUPERFAMILY SSF51445 4 359 3.16E-94 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS26045 7d4e93d9b0e64c7ed8a440d3fe589d49 537 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 367 532 6.7E-10 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 Gene3D G3DSA:3.40.50.2300 1 122 1.7E-31 T 29-03-2018 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 SMART SM00448 2 112 4.3E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 SMART SM00862 146 222 8.0E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 Pfam PF00072 Response regulator receiver domain 4 112 1.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 Gene3D G3DSA:1.10.10.10 123 225 3.7E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 7.7E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 SUPERFAMILY SSF46894 123 223 3.68E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS30780 0621b13ffd5978c3303fbb4485eba70e 225 SUPERFAMILY SSF52172 3 125 9.82E-38 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS12050 e333cb29a12c000ccbf151d38decbd61 245 Pfam PF13649 Methyltransferase domain 45 138 8.7E-20 T 29-03-2018 A616_RS12050 e333cb29a12c000ccbf151d38decbd61 245 Gene3D G3DSA:3.40.50.150 4 239 4.0E-34 T 29-03-2018 A616_RS12050 e333cb29a12c000ccbf151d38decbd61 245 SUPERFAMILY SSF53335 5 244 3.85E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS09200 cd5e08e6201ca622969214bbdbf2749b 405 Gene3D G3DSA:2.30.40.10 360 403 0.0037 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09200 cd5e08e6201ca622969214bbdbf2749b 405 Pfam PF07969 Amidohydrolase family 110 401 3.3E-21 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS09200 cd5e08e6201ca622969214bbdbf2749b 405 SUPERFAMILY SSF51338 31 74 2.8E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09200 cd5e08e6201ca622969214bbdbf2749b 405 Gene3D G3DSA:2.30.40.10 1 78 4.5E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09200 cd5e08e6201ca622969214bbdbf2749b 405 Gene3D G3DSA:3.20.20.140 79 353 3.7E-31 T 29-03-2018 A616_RS09200 cd5e08e6201ca622969214bbdbf2749b 405 SUPERFAMILY SSF51556 67 372 4.9E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS08100 135c70f14141921952856f1f8446597b 159 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 7.9E-66 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A616_RS08100 135c70f14141921952856f1f8446597b 159 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 85.652 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A616_RS08100 135c70f14141921952856f1f8446597b 159 Pfam PF03477 ATP cone domain 50 136 1.7E-17 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A616_RS15180 e5e6399231789e46196257524f197bdc 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 1.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS15180 e5e6399231789e46196257524f197bdc 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 1.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS15180 e5e6399231789e46196257524f197bdc 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 91 1.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS15180 e5e6399231789e46196257524f197bdc 249 SUPERFAMILY SSF53474 2 248 1.26E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15180 e5e6399231789e46196257524f197bdc 249 Pfam PF00561 alpha/beta hydrolase fold 13 124 4.9E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS15180 e5e6399231789e46196257524f197bdc 249 Gene3D G3DSA:3.40.50.1820 1 249 2.5E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS29430 58da058f1cd7715d7b8365da3a00b64e 260 Pfam PF00691 OmpA family 150 249 2.9E-20 T 29-03-2018 IPR006665 OmpA-like domain A616_RS29430 58da058f1cd7715d7b8365da3a00b64e 260 SUPERFAMILY SSF103088 137 255 2.09E-32 T 29-03-2018 IPR006665 OmpA-like domain A616_RS29430 58da058f1cd7715d7b8365da3a00b64e 260 Gene3D G3DSA:3.30.1330.60 106 260 6.1E-41 T 29-03-2018 IPR006665 OmpA-like domain A616_RS10035 7457e7ae3e583f49c001483cf4118733 294 SUPERFAMILY SSF53448 3 241 1.13E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10035 7457e7ae3e583f49c001483cf4118733 294 Gene3D G3DSA:3.90.550.10 2 264 6.6E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10035 7457e7ae3e583f49c001483cf4118733 294 Pfam PF00535 Glycosyl transferase family 2 10 173 7.4E-27 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS27445 30f0dba213f49b17f8b44b72dbea834d 275 Gene3D G3DSA:3.30.450.20 15 103 8.4E-4 T 29-03-2018 A616_RS27445 30f0dba213f49b17f8b44b72dbea834d 275 SUPERFAMILY SSF58104 108 266 2.49E-31 T 29-03-2018 A616_RS27445 30f0dba213f49b17f8b44b72dbea834d 275 Gene3D G3DSA:1.10.287.950 104 274 1.1E-30 T 29-03-2018 A616_RS27445 30f0dba213f49b17f8b44b72dbea834d 275 SUPERFAMILY SSF103190 24 106 4.08E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS27445 30f0dba213f49b17f8b44b72dbea834d 275 SMART SM00283 90 275 0.0031 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS27445 30f0dba213f49b17f8b44b72dbea834d 275 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 151 266 2.1E-22 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 SMART SM00382 37 179 2.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 Gene3D G3DSA:1.20.272.10 243 364 1.1E-17 T 29-03-2018 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 359 3.0E-11 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 Pfam PF13177 DNA polymerase III, delta subunit 20 177 1.6E-47 T 29-03-2018 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 9.1E-143 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 Gene3D G3DSA:1.10.8.60 167 242 1.0E-20 T 29-03-2018 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 Gene3D G3DSA:3.40.50.300 1 166 1.6E-43 T 29-03-2018 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 SUPERFAMILY SSF52540 32 223 9.24E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 SUPERFAMILY SSF48019 244 359 2.13E-23 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 7.3E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS00510 50c3641a8b108532fc8377cf22d4513e 567 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 7.3E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 A616_RS16025 63e94f47545af5e93a1f8629fa89a519 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 1.0E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS16025 63e94f47545af5e93a1f8629fa89a519 312 SUPERFAMILY SSF161098 91 289 1.03E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS16025 63e94f47545af5e93a1f8629fa89a519 312 Gene3D G3DSA:1.10.3720.10 1 293 1.6E-46 T 29-03-2018 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 SUPERFAMILY SSF102645 193 405 7.46E-80 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 402 1.7E-146 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 SUPERFAMILY SSF52507 2 181 1.57E-61 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 Pfam PF02441 Flavoprotein 7 180 3.1E-45 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 195 377 2.4E-76 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 Gene3D G3DSA:3.40.50.10300 189 410 9.8E-75 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A616_RS20795 c8565880acc009b40349aae251a0aa9f 415 Gene3D G3DSA:3.40.50.1950 1 188 1.1E-55 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS26435 975a9b2b6e90a1793ae2e48045070eb9 409 Pfam PF00149 Calcineurin-like phosphoesterase 34 251 4.1E-17 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS26435 975a9b2b6e90a1793ae2e48045070eb9 409 Pfam PF13285 Domain of unknown function (DUF4073) 252 408 5.8E-93 T 29-03-2018 IPR025142 Domain of unknown function DUF4073 A616_RS26435 975a9b2b6e90a1793ae2e48045070eb9 409 Gene3D G3DSA:3.60.21.10 20 332 2.1E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS26435 975a9b2b6e90a1793ae2e48045070eb9 409 SUPERFAMILY SSF56300 32 321 2.95E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 Pfam PF02040 Arsenical pump membrane protein 5 425 3.5E-182 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 4 427 2.9E-199 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS02815 a1d3465d451220ec68371e9767f74f79 430 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 3.9E-106 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A616_RS01905 b7060f3035fb0cc56b9748c81fc4e0f4 368 Pfam PF01212 Beta-eliminating lyase 40 297 4.9E-35 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A616_RS01905 b7060f3035fb0cc56b9748c81fc4e0f4 368 Gene3D G3DSA:3.40.640.10 2 242 8.5E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS01905 b7060f3035fb0cc56b9748c81fc4e0f4 368 SUPERFAMILY SSF53383 38 306 1.02E-62 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS11495 4f25e8b60244ebc67f9e2dfc8f3eeceb 142 SUPERFAMILY SSF55811 4 123 3.93E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS11495 4f25e8b60244ebc67f9e2dfc8f3eeceb 142 Pfam PF00293 NUDIX domain 2 120 5.4E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS11495 4f25e8b60244ebc67f9e2dfc8f3eeceb 142 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A616_RS11495 4f25e8b60244ebc67f9e2dfc8f3eeceb 142 Gene3D G3DSA:3.90.79.10 2 140 5.5E-21 T 29-03-2018 A616_RS14855 9a28ee9288161f39c5fedabaee01d942 521 SUPERFAMILY SSF52096 274 521 2.22E-91 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS14855 9a28ee9288161f39c5fedabaee01d942 521 SUPERFAMILY SSF52096 7 262 4.84E-82 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS14855 9a28ee9288161f39c5fedabaee01d942 521 Gene3D G3DSA:3.90.226.10 262 519 2.4E-76 T 29-03-2018 A616_RS14855 9a28ee9288161f39c5fedabaee01d942 521 Pfam PF01039 Carboxyl transferase domain 35 519 7.9E-197 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A616_RS14855 9a28ee9288161f39c5fedabaee01d942 521 Gene3D G3DSA:3.90.226.10 5 261 6.8E-83 T 29-03-2018 A616_RS17665 031ef40fef619d1de69fdba49d294681 219 SUPERFAMILY SSF46785 12 198 7.61E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17665 031ef40fef619d1de69fdba49d294681 219 Pfam PF01022 Bacterial regulatory protein, arsR family 12 58 2.0E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS17665 031ef40fef619d1de69fdba49d294681 219 Gene3D G3DSA:1.10.10.10 4 163 9.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25795 730898dcd134bc9827f6c504d3ed4aa1 323 Pfam PF00892 EamA-like transporter family 7 145 1.7E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS32145 63cf2613ee91f844a4e18f441fface81 71 Gene3D G3DSA:2.30.30.100 6 50 3.6E-5 T 29-03-2018 A616_RS16170 9a47775d3c71b563c6d4b62e750b1027 468 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 146 343 3.4E-26 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT A616_RS16170 9a47775d3c71b563c6d4b62e750b1027 468 PIRSF PIRSF500217 1 468 6.8E-144 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 A616_RS16170 9a47775d3c71b563c6d4b62e750b1027 468 PIRSF PIRSF016636 1 468 7.2E-141 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SMART SM00316 189 259 9.6E-29 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SMART SM00316 103 170 3.9E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SMART SM00316 274 345 5.3E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SMART SM00316 16 87 4.2E-20 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SUPERFAMILY SSF50249 91 175 1.0E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SUPERFAMILY SSF50249 9 110 7.26E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 84 103 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 36 50 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 289 308 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 125 142 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 18 36 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 108 124 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 211 232 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 328 346 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 PRINTS PR00681 Ribosomal protein S1 signature 154 174 2.0E-58 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SUPERFAMILY SSF50249 259 349 2.0E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 SUPERFAMILY SSF50249 189 276 1.64E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Pfam PF00575 S1 RNA binding domain 273 345 3.0E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Pfam PF00575 S1 RNA binding domain 102 170 5.2E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Pfam PF00575 S1 RNA binding domain 187 259 3.4E-25 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Pfam PF00575 S1 RNA binding domain 17 87 9.5E-18 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Gene3D G3DSA:2.40.50.140 98 176 9.8E-14 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Gene3D G3DSA:2.40.50.140 180 264 6.5E-29 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Gene3D G3DSA:2.40.50.140 8 93 5.7E-20 T 29-03-2018 A616_RS13645 183a6058dc58f5f90de90c26bb240d3d 390 Gene3D G3DSA:2.40.50.140 276 374 3.7E-26 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 Gene3D G3DSA:1.20.1250.20 240 453 1.7E-14 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 Pfam PF07690 Major Facilitator Superfamily 17 397 4.6E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 SUPERFAMILY SSF103473 236 444 1.01E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 SUPERFAMILY SSF103473 12 193 1.01E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 Gene3D G3DSA:1.20.1250.20 7 192 5.8E-33 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 290 314 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 162 186 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 255 280 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 345 365 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 2.1E-29 T 29-03-2018 A616_RS05745 0c9d35c6a4983aaf129ba88989bbdb2b 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 221 239 2.1E-29 T 29-03-2018 A616_RS12690 3ec37a6b9713e758cef8375981b27d98 347 Pfam PF01699 Sodium/calcium exchanger protein 202 340 1.5E-16 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A616_RS12690 3ec37a6b9713e758cef8375981b27d98 347 Pfam PF01699 Sodium/calcium exchanger protein 29 178 8.9E-17 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A616_RS12690 3ec37a6b9713e758cef8375981b27d98 347 TIGRFAM TIGR00378 cax: calcium/proton exchanger 16 345 1.1E-102 T 29-03-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 A616_RS10245 a40dc8b275bd572ca30b6bc76a06e091 251 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 167 239 3.3E-11 T 29-03-2018 IPR018911 Bacterial spore germination, immunoglobulin-like domain A616_RS10245 a40dc8b275bd572ca30b6bc76a06e091 251 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 65 134 2.1E-9 T 29-03-2018 IPR018911 Bacterial spore germination, immunoglobulin-like domain A616_RS18420 abc878b7dc74081c1bec45531aa8fd71 124 Pfam PF13564 DoxX-like family 15 106 1.7E-16 T 29-03-2018 IPR032808 DoxX family A616_RS09335 6b17373b438f3e0d6b48ef404aeeda2d 209 SUPERFAMILY SSF55811 4 157 1.52E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS09335 6b17373b438f3e0d6b48ef404aeeda2d 209 Pfam PF00293 NUDIX domain 41 155 4.0E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS09335 6b17373b438f3e0d6b48ef404aeeda2d 209 Gene3D G3DSA:3.90.79.10 1 182 2.1E-22 T 29-03-2018 A616_RS29465 3f60f0b8a899819ecca4ccab0825f4b4 230 Gene3D G3DSA:3.90.550.10 3 230 2.8E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS29465 3f60f0b8a899819ecca4ccab0825f4b4 230 Pfam PF02348 Cytidylyltransferase 9 141 1.1E-27 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 A616_RS29465 3f60f0b8a899819ecca4ccab0825f4b4 230 SUPERFAMILY SSF53448 6 229 5.63E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS02910 b83c8538623aea7222a3103682100867 164 Pfam PF13581 Histidine kinase-like ATPase domain 16 145 2.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02910 b83c8538623aea7222a3103682100867 164 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 7 161 6.6E-60 T 29-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A616_RS02910 b83c8538623aea7222a3103682100867 164 Gene3D G3DSA:3.30.565.10 7 151 1.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02910 b83c8538623aea7222a3103682100867 164 SUPERFAMILY SSF55874 33 138 4.58E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS02910 b83c8538623aea7222a3103682100867 164 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 5 161 37.554 T 29-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 Gene3D G3DSA:1.10.10.10 57 143 8.6E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 SUPERFAMILY SSF53155 1 65 1.96E-13 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 111 117 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 56 5.6E-5 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 SUPERFAMILY SSF46767 60 142 1.29E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 61 140 2.1E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 Gene3D G3DSA:3.30.160.70 1 56 7.9E-13 T 29-03-2018 A616_RS20920 e9d92cc7a7cb53259fc3cbf9e28240a5 148 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 62 141 4.0E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS15395 c2216b3317a3fccb3b234fee76e36e7e 135 SUPERFAMILY SSF54637 15 134 1.42E-19 T 29-03-2018 IPR029069 HotDog domain A616_RS15395 c2216b3317a3fccb3b234fee76e36e7e 135 Gene3D G3DSA:3.10.129.10 4 134 2.7E-20 T 29-03-2018 A616_RS15395 c2216b3317a3fccb3b234fee76e36e7e 135 Pfam PF13452 N-terminal half of MaoC dehydratase 9 125 1.3E-20 T 29-03-2018 A616_RS14310 28ad4c1dc0a866d8a777c8eb167582d8 320 Gene3D G3DSA:3.60.70.12 1 319 1.7E-108 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS14310 28ad4c1dc0a866d8a777c8eb167582d8 320 SUPERFAMILY SSF56266 3 317 5.23E-75 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS14310 28ad4c1dc0a866d8a777c8eb167582d8 320 Pfam PF03576 Peptidase family S58 4 310 2.6E-60 T 29-03-2018 IPR005321 Peptidase S58, DmpA A616_RS10515 fdb4927daf2228a00bd8df28b282e8bf 225 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 206 4.7E-33 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A616_RS10515 fdb4927daf2228a00bd8df28b282e8bf 225 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 109 202 7.5E-28 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A616_RS10515 fdb4927daf2228a00bd8df28b282e8bf 225 SUPERFAMILY SSF63848 108 209 1.7E-28 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A616_RS10515 fdb4927daf2228a00bd8df28b282e8bf 225 Gene3D G3DSA:3.30.750.50 8 96 1.1E-26 T 29-03-2018 A616_RS10515 fdb4927daf2228a00bd8df28b282e8bf 225 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 209 20.78 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A616_RS10515 fdb4927daf2228a00bd8df28b282e8bf 225 Gene3D G3DSA:2.160.20.70 97 212 1.4E-31 T 29-03-2018 A616_RS25075 4d84300a940e44af6dd07510b5df1b89 235 SUPERFAMILY SSF53448 9 230 7.5E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS25075 4d84300a940e44af6dd07510b5df1b89 235 Gene3D G3DSA:3.90.550.10 4 234 3.3E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS25075 4d84300a940e44af6dd07510b5df1b89 235 Pfam PF00535 Glycosyl transferase family 2 11 182 3.1E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS00385 649592f62607c4272cf944f86ec79d41 165 Pfam PF04308 Ribonuclease H-like 25 165 4.7E-42 T 29-03-2018 IPR007405 Bacteriophage KVP40, Orf299 A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 SUPERFAMILY SSF53187 298 327 7.33E-59 T 29-03-2018 A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 SUPERFAMILY SSF53187 4 198 7.33E-59 T 29-03-2018 A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 SUPERFAMILY SSF53187 370 436 7.33E-59 T 29-03-2018 A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 PIRSF PIRSF037227 1 467 2.2E-215 T 29-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 418 5.3E-87 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 SUPERFAMILY SSF55031 187 291 2.39E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 Gene3D G3DSA:3.40.630.10 360 451 8.6E-13 T 29-03-2018 A616_RS04765 76db01e19636d8dc96c9f80c048c98b4 467 Gene3D G3DSA:3.40.630.10 1 309 8.2E-49 T 29-03-2018 A616_RS09025 eb82617fd42e8249f309230ebf159dfd 654 Pfam PF01757 Acyltransferase family 13 348 6.4E-25 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS09025 eb82617fd42e8249f309230ebf159dfd 654 Gene3D G3DSA:3.40.50.1110 452 640 2.1E-19 T 29-03-2018 A616_RS09025 eb82617fd42e8249f309230ebf159dfd 654 SUPERFAMILY SSF52266 480 638 2.83E-15 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 SUPERFAMILY SSF51998 160 682 7.32E-162 T 29-03-2018 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 Pfam PF08343 Ribonucleotide reductase N-terminal 3 82 1.3E-23 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 3 694 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 87 682 6.0E-162 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 Gene3D G3DSA:3.20.70.20 63 685 6.9E-147 T 29-03-2018 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 85 156 2.5E-11 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 Pfam PF02867 Ribonucleotide reductase, barrel domain 161 678 8.3E-127 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 453 475 1.3E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 481 504 1.3E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 370 381 1.3E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 563 590 1.3E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 236 255 1.3E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 552 574 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS18190 b0dfb185ac4afa07c0791ddf5e484aae 694 SUPERFAMILY SSF48168 3 159 2.49E-42 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 128 213 2.8E-18 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 124 210 21.746 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 SUPERFAMILY SSF101386 126 214 1.42E-26 T 29-03-2018 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 35 106 5.9E-35 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 10 214 36.924 T 29-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 127 210 1.1E-32 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 8 111 29.969 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 57 106 4.0E-20 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 SUPERFAMILY SSF141734 7 114 9.55E-48 T 29-03-2018 A616_RS29200 6b23d8ae3475d4fc246ae5a72c6ef4cb 214 Gene3D G3DSA:1.10.287.1080 123 214 7.8E-25 T 29-03-2018 A616_RS03535 2d4c1cfacaa8e1bee441dd3aa9518dd5 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 334 1.3E-54 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS03535 2d4c1cfacaa8e1bee441dd3aa9518dd5 371 Gene3D G3DSA:3.40.1830.10 2 165 2.0E-41 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS03535 2d4c1cfacaa8e1bee441dd3aa9518dd5 371 SUPERFAMILY SSF144052 1 360 2.22E-106 T 29-03-2018 A616_RS13320 3e89161184178105948f903af0eb0780 390 Gene3D G3DSA:3.20.20.140 2 261 1.8E-14 T 29-03-2018 A616_RS13320 3e89161184178105948f903af0eb0780 390 Pfam PF13263 PHP-associated 195 241 1.3E-6 T 29-03-2018 A616_RS13320 3e89161184178105948f903af0eb0780 390 SUPERFAMILY SSF47781 308 370 6.3E-8 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS13320 3e89161184178105948f903af0eb0780 390 Gene3D G3DSA:1.10.150.20 318 375 9.4E-8 T 29-03-2018 A616_RS13320 3e89161184178105948f903af0eb0780 390 SUPERFAMILY SSF89550 5 244 1.73E-13 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS32210 ab1d380fa70972080715cb7303990889 259 Pfam PF13205 Bacterial Ig-like domain 39 140 3.5E-9 T 29-03-2018 IPR032812 SbsA, Ig-like domain A616_RS32210 ab1d380fa70972080715cb7303990889 259 Pfam PF13205 Bacterial Ig-like domain 145 256 6.1E-12 T 29-03-2018 IPR032812 SbsA, Ig-like domain A616_RS32210 ab1d380fa70972080715cb7303990889 259 Gene3D G3DSA:2.60.40.1220 33 129 5.5E-4 T 29-03-2018 A616_RS32210 ab1d380fa70972080715cb7303990889 259 Gene3D G3DSA:2.60.40.1220 151 247 0.0034 T 29-03-2018 A616_RS29880 97d033887b039139bd507dc684566a60 172 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 2.1E-25 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29880 97d033887b039139bd507dc684566a60 172 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 10 160 43.695 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29880 97d033887b039139bd507dc684566a60 172 SUPERFAMILY SSF56770 18 163 3.92E-68 T 29-03-2018 A616_RS29880 97d033887b039139bd507dc684566a60 172 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 161 2.3E-74 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29880 97d033887b039139bd507dc684566a60 172 Gene3D G3DSA:3.40.50.700 17 171 1.4E-49 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 SUPERFAMILY SSF118215 30 441 1.7E-89 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 1.8E-96 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 Gene3D G3DSA:1.10.3860.10 20 449 1.7E-84 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 3.7E-18 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 3.7E-18 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 3.7E-18 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 3.7E-18 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS04720 455ceb14dbd793d33806d05a0fec8163 461 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 3.7E-18 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A616_RS05125 6cdf5dc5fcd222ed406cf2af52dd9010 245 Gene3D G3DSA:2.40.33.20 1 244 2.0E-41 T 29-03-2018 A616_RS05125 6cdf5dc5fcd222ed406cf2af52dd9010 245 Pfam PF03476 MOSC N-terminal beta barrel domain 5 67 1.2E-7 T 29-03-2018 IPR005303 MOSC, N-terminal beta barrel A616_RS05125 6cdf5dc5fcd222ed406cf2af52dd9010 245 Pfam PF03473 MOSC domain 121 235 1.3E-19 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 A616_RS05125 6cdf5dc5fcd222ed406cf2af52dd9010 245 SUPERFAMILY SSF50800 124 236 2.51E-24 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain A616_RS05125 6cdf5dc5fcd222ed406cf2af52dd9010 245 SUPERFAMILY SSF50800 4 47 2.51E-24 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain A616_RS18615 82ba6930230c3041e8e7ef3a847f32ec 116 Gene3D G3DSA:1.10.10.10 4 108 3.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18615 82ba6930230c3041e8e7ef3a847f32ec 116 Pfam PF12802 MarR family 36 92 1.5E-10 T 29-03-2018 A616_RS18615 82ba6930230c3041e8e7ef3a847f32ec 116 SMART SM00347 30 115 1.8E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS18615 82ba6930230c3041e8e7ef3a847f32ec 116 SUPERFAMILY SSF46785 10 103 8.52E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22595 8c57ff350ac711f09ca984bd0a1b0285 215 Pfam PF07486 Cell Wall Hydrolase 116 213 1.6E-27 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A616_RS22595 8c57ff350ac711f09ca984bd0a1b0285 215 Gene3D G3DSA:1.10.101.10 23 98 7.9E-23 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS22595 8c57ff350ac711f09ca984bd0a1b0285 215 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 28 214 1.2E-79 T 29-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 A616_RS22595 8c57ff350ac711f09ca984bd0a1b0285 215 SUPERFAMILY SSF47090 32 93 9.94E-22 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS22595 8c57ff350ac711f09ca984bd0a1b0285 215 Pfam PF01471 Putative peptidoglycan binding domain 40 93 3.6E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 174 5.0E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 SUPERFAMILY SSF88946 2 107 1.18E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 Pfam PF08281 Sigma-70, region 4 121 171 2.7E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 Gene3D G3DSA:1.10.10.10 104 185 6.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 Pfam PF04542 Sigma-70 region 2 22 88 5.5E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 Gene3D G3DSA:1.10.1740.10 1 103 4.0E-25 T 29-03-2018 A616_RS31560 16baf552f15247e96a12ed9de3cf1398 185 SUPERFAMILY SSF88659 107 176 1.14E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS31120 4e3d634effe30d3fd1c01b015146e7bd 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 252 4.7E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31120 4e3d634effe30d3fd1c01b015146e7bd 262 SUPERFAMILY SSF161098 8 253 1.24E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31120 4e3d634effe30d3fd1c01b015146e7bd 262 Gene3D G3DSA:1.10.3720.10 4 252 1.4E-42 T 29-03-2018 A616_RS08850 ac4154f7700caf2f04995de7aed73253 386 Pfam PF02342 TerD domain 3 175 5.5E-55 T 29-03-2018 IPR003325 TerD domain GO:0006950 A616_RS08850 ac4154f7700caf2f04995de7aed73253 386 Gene3D G3DSA:2.60.60.30 208 354 6.7E-17 T 29-03-2018 A616_RS08850 ac4154f7700caf2f04995de7aed73253 386 Gene3D G3DSA:2.60.60.30 15 174 7.9E-40 T 29-03-2018 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 445 1.1E-214 T 29-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 Pfam PF07690 Major Facilitator Superfamily 34 406 3.4E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 425 1.5E-147 T 29-03-2018 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 Gene3D G3DSA:1.20.1250.20 248 449 8.7E-31 T 29-03-2018 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 SUPERFAMILY SSF103473 10 443 9.02E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 PIRSF PIRSF002808 5 454 6.3E-161 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 Gene3D G3DSA:1.20.1250.20 18 230 9.2E-29 T 29-03-2018 A616_RS01775 c0d9a4377fdf44b0cd928256e997a866 454 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 29-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 A616_RS12875 ef25f520933b5f5e120c7b87202f2bfd 228 Gene3D G3DSA:1.10.3720.10 3 226 1.8E-38 T 29-03-2018 A616_RS12875 ef25f520933b5f5e120c7b87202f2bfd 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 25 209 3.1E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12875 ef25f520933b5f5e120c7b87202f2bfd 228 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 219 1.4E-76 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 A616_RS12875 ef25f520933b5f5e120c7b87202f2bfd 228 SUPERFAMILY SSF161098 6 217 1.44E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS13220 68b812cc3206b26690aa22999a263859 124 Gene3D G3DSA:3.10.180.10 1 124 1.4E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS13220 68b812cc3206b26690aa22999a263859 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 120 2.6E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS13220 68b812cc3206b26690aa22999a263859 124 SUPERFAMILY SSF54593 9 123 5.78E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS14955 460ef9fb431216af1704e0a51e44f2d4 331 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 34 316 4.5E-59 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 A616_RS14955 460ef9fb431216af1704e0a51e44f2d4 331 Gene3D G3DSA:3.40.190.10 28 139 1.7E-13 T 29-03-2018 A616_RS14955 460ef9fb431216af1704e0a51e44f2d4 331 Pfam PF13379 NMT1-like family 28 264 1.6E-25 T 29-03-2018 A616_RS14955 460ef9fb431216af1704e0a51e44f2d4 331 SUPERFAMILY SSF53850 31 261 5.18E-40 T 29-03-2018 A616_RS14955 460ef9fb431216af1704e0a51e44f2d4 331 Gene3D G3DSA:3.40.190.10 140 325 1.6E-30 T 29-03-2018 A616_RS24615 52d7b320a2f3b31df3ade32ca1a0efd0 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 2.5E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS24615 52d7b320a2f3b31df3ade32ca1a0efd0 123 SUPERFAMILY SSF54593 6 121 6.44E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24615 52d7b320a2f3b31df3ade32ca1a0efd0 123 Gene3D G3DSA:3.10.180.10 3 121 1.4E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS09710 e225ef6ce1b505bee1f195c000f3f596 257 SUPERFAMILY SSF52096 4 255 2.4E-89 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS09710 e225ef6ce1b505bee1f195c000f3f596 257 Gene3D G3DSA:3.90.226.10 1 217 2.8E-77 T 29-03-2018 A616_RS09710 e225ef6ce1b505bee1f195c000f3f596 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 256 1.4E-71 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A616_RS09710 e225ef6ce1b505bee1f195c000f3f596 257 Gene3D G3DSA:1.10.12.10 218 255 1.9E-18 T 29-03-2018 IPR014748 Crontonase, C-terminal A616_RS09710 e225ef6ce1b505bee1f195c000f3f596 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A616_RS23805 1f7e83fb6981c44686139cfca08607a2 277 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 78 91 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A616_RS23805 1f7e83fb6981c44686139cfca08607a2 277 Gene3D G3DSA:3.40.190.10 38 152 1.5E-27 T 29-03-2018 A616_RS23805 1f7e83fb6981c44686139cfca08607a2 277 SUPERFAMILY SSF53850 1 274 6.52E-68 T 29-03-2018 A616_RS23805 1f7e83fb6981c44686139cfca08607a2 277 Gene3D G3DSA:3.40.190.10 153 270 1.7E-29 T 29-03-2018 A616_RS23805 1f7e83fb6981c44686139cfca08607a2 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 272 1.4E-60 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS23805 1f7e83fb6981c44686139cfca08607a2 277 SMART SM00062 55 274 2.3E-67 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS31445 49b70fca64000a6cac3de148d04415cc 627 SUPERFAMILY SSF53448 239 530 1.13E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31445 49b70fca64000a6cac3de148d04415cc 627 Pfam PF00535 Glycosyl transferase family 2 249 425 1.8E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS31445 49b70fca64000a6cac3de148d04415cc 627 Pfam PF07238 PilZ domain 72 172 1.5E-5 T 29-03-2018 IPR009875 PilZ domain GO:0035438 A616_RS31445 49b70fca64000a6cac3de148d04415cc 627 ProDom PD339107 ALGINATE ALG8 BIOSYNTHESIS TRANSFERASE TRANSMEMBRANE MEMBRANE 2.4.1.- GLYCOSYL GLYCOSYLTRANSFERASE PRECURSOR 241 528 2.0E-7 T 29-03-2018 A616_RS31445 49b70fca64000a6cac3de148d04415cc 627 Gene3D G3DSA:3.90.550.10 234 515 6.8E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31445 49b70fca64000a6cac3de148d04415cc 627 Gene3D G3DSA:2.40.10.220 70 179 1.2E-8 T 29-03-2018 A616_RS08800 e5d2d4ccbeab719e1d5de85c5ce729a4 511 PIRSF PIRSF002741 2 511 3.9E-123 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS08800 e5d2d4ccbeab719e1d5de85c5ce729a4 511 Gene3D G3DSA:3.40.190.10 189 281 4.6E-28 T 29-03-2018 A616_RS08800 e5d2d4ccbeab719e1d5de85c5ce729a4 511 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 432 1.4E-97 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS08800 e5d2d4ccbeab719e1d5de85c5ce729a4 511 Gene3D G3DSA:3.10.105.10 282 482 6.9E-55 T 29-03-2018 A616_RS08800 e5d2d4ccbeab719e1d5de85c5ce729a4 511 Gene3D G3DSA:3.90.76.10 52 188 6.4E-37 T 29-03-2018 A616_RS08800 e5d2d4ccbeab719e1d5de85c5ce729a4 511 SUPERFAMILY SSF53850 40 497 2.68E-135 T 29-03-2018 A616_RS27890 93e47f33c271a52cfefbc83f24192025 515 Gene3D G3DSA:3.40.50.410 168 365 1.0E-36 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27890 93e47f33c271a52cfefbc83f24192025 515 Pfam PF12034 Domain of unknown function (DUF3520) 357 509 2.2E-44 T 29-03-2018 IPR021908 Protein of unknown function DUF3520 A616_RS27890 93e47f33c271a52cfefbc83f24192025 515 SUPERFAMILY SSF53300 177 353 2.23E-39 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27890 93e47f33c271a52cfefbc83f24192025 515 Pfam PF00092 von Willebrand factor type A domain 181 351 2.1E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27890 93e47f33c271a52cfefbc83f24192025 515 SMART SM00327 179 355 4.1E-30 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27890 93e47f33c271a52cfefbc83f24192025 515 Pfam PF12450 von Willebrand factor 74 164 1.2E-30 T 29-03-2018 IPR022156 Uncharacterised protein YfbK, N-terminal A616_RS14375 92278c7a599eae99062f491cc52654c8 298 SUPERFAMILY SSF54001 167 297 2.45E-36 T 29-03-2018 A616_RS14375 92278c7a599eae99062f491cc52654c8 298 Gene3D G3DSA:3.90.1720.10 168 298 7.0E-37 T 29-03-2018 A616_RS14375 92278c7a599eae99062f491cc52654c8 298 SUPERFAMILY SSF54001 30 158 2.35E-22 T 29-03-2018 A616_RS14375 92278c7a599eae99062f491cc52654c8 298 Pfam PF00877 NlpC/P60 family 50 150 6.6E-12 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS14375 92278c7a599eae99062f491cc52654c8 298 Pfam PF00877 NlpC/P60 family 186 295 6.7E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A616_RS14375 92278c7a599eae99062f491cc52654c8 298 Gene3D G3DSA:3.90.1720.10 27 158 3.5E-23 T 29-03-2018 A616_RS20525 479acaf3e4d2b90a61495a5950736428 306 SUPERFAMILY SSF52540 2 277 7.63E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20525 479acaf3e4d2b90a61495a5950736428 306 Gene3D G3DSA:1.10.8.300 194 302 2.8E-31 T 29-03-2018 A616_RS20525 479acaf3e4d2b90a61495a5950736428 306 PIRSF PIRSF002849 1 306 2.0E-128 T 29-03-2018 A616_RS20525 479acaf3e4d2b90a61495a5950736428 306 Gene3D G3DSA:3.40.50.300 12 178 1.1E-29 T 29-03-2018 A616_RS20525 479acaf3e4d2b90a61495a5950736428 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 31 161 6.1E-63 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A616_RS21280 1eeec9e2970adcbd6c90e73cb8cb8681 261 Pfam PF03799 Cell division protein FtsQ 118 216 3.1E-4 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB A616_RS21280 1eeec9e2970adcbd6c90e73cb8cb8681 261 Hamap MF_00912 Cell division protein DivIB [divIB]. 4 247 28.94 T 29-03-2018 IPR026580 Cell division protein DivIB A616_RS21280 1eeec9e2970adcbd6c90e73cb8cb8681 261 Pfam PF08478 POTRA domain, FtsQ-type 46 114 2.7E-12 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 7.9E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 SUPERFAMILY SSF48498 79 178 5.48E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 Gene3D G3DSA:1.10.10.60 1 57 2.4E-16 T 29-03-2018 A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 SUPERFAMILY SSF46689 4 72 6.98E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 Gene3D G3DSA:1.10.357.10 58 187 1.9E-20 T 29-03-2018 A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 Pfam PF08359 YsiA-like protein, C-terminal region 63 162 2.4E-5 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A616_RS11865 b9714081d6cc532c68cfa7b970e9313b 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS26190 6b2d5561a0dddd382d5859fd2c9abb68 145 Gene3D G3DSA:2.60.60.20 24 136 3.7E-17 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 A616_RS26190 6b2d5561a0dddd382d5859fd2c9abb68 145 SUPERFAMILY SSF49723 39 136 2.01E-17 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 A616_RS26190 6b2d5561a0dddd382d5859fd2c9abb68 145 Pfam PF01477 PLAT/LH2 domain 42 132 5.1E-13 T 29-03-2018 IPR001024 PLAT/LH2 domain GO:0005515 A616_RS27945 d6baade8f002578f51d0e2cfe44d25dc 141 PRINTS PR00502 NUDIX hydrolase family signature 51 66 5.2E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS27945 d6baade8f002578f51d0e2cfe44d25dc 141 PRINTS PR00502 NUDIX hydrolase family signature 37 51 5.2E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A616_RS27945 d6baade8f002578f51d0e2cfe44d25dc 141 SUPERFAMILY SSF55811 7 139 5.01E-32 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS27945 d6baade8f002578f51d0e2cfe44d25dc 141 Pfam PF00293 NUDIX domain 9 125 1.2E-21 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS27945 d6baade8f002578f51d0e2cfe44d25dc 141 Gene3D G3DSA:3.90.79.10 6 139 4.2E-29 T 29-03-2018 A616_RS17345 0444a94958098bdc0d627ea68b832181 113 Pfam PF10544 T5orf172 domain 22 108 3.6E-11 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding A616_RS17345 0444a94958098bdc0d627ea68b832181 113 SUPERFAMILY SSF82771 20 84 1.7E-6 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS17345 0444a94958098bdc0d627ea68b832181 113 Gene3D G3DSA:3.40.1440.10 9 112 3.2E-7 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS17345 0444a94958098bdc0d627ea68b832181 113 SMART SM00974 27 108 2.4E-4 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding A616_RS26310 4cb310375e3bdb2c6e5bdc8c9652a195 493 Pfam PF13777 Domain of unknown function (DUF4173) 261 448 6.7E-59 T 29-03-2018 IPR025231 Domain of unknown function DUF4173 A616_RS27665 0d4eae17d710cc10f21bf9dd099535f4 799 Gene3D G3DSA:3.40.50.880 157 354 5.0E-15 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS27665 0d4eae17d710cc10f21bf9dd099535f4 799 SUPERFAMILY SSF52317 142 333 4.58E-14 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 PRINTS PR00474 Glutamate 5-kinase family signature 212 232 9.0E-12 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 PRINTS PR00474 Glutamate 5-kinase family signature 32 46 9.0E-12 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 9.0E-12 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 PIRSF PIRSF000728 1 260 1.2E-87 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 SUPERFAMILY SSF53633 3 259 6.94E-66 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 260 30.704 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 Pfam PF00696 Amino acid kinase family 4 238 1.9E-44 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 237 9.3E-77 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A616_RS29365 28ffb916880ae8140a47d9764fbc8906 265 Gene3D G3DSA:3.40.1160.10 1 264 8.3E-57 T 29-03-2018 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 Gene3D G3DSA:3.40.50.20 1 119 5.4E-35 T 29-03-2018 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 105 116 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 Gene3D G3DSA:3.30.1490.20 120 209 2.0E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 Pfam PF07478 D-ala D-ala ligase C-terminus 166 343 4.4E-61 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 PIRSF PIRSF039102 1 350 6.4E-109 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 347 36.889 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 SUPERFAMILY SSF56059 138 348 4.09E-50 T 29-03-2018 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 Gene3D G3DSA:3.30.470.20 210 350 2.7E-35 T 29-03-2018 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 Pfam PF01820 D-ala D-ala ligase N-terminus 6 128 5.7E-29 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 346 7.7E-94 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 289 317 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS03510 d701742c1ba249d49d8ec464a27273e0 350 SUPERFAMILY SSF52440 3 137 8.63E-36 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 Gene3D G3DSA:3.40.50.300 1 253 4.0E-80 T 29-03-2018 A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 Gene3D G3DSA:2.40.50.140 261 332 2.6E-4 T 29-03-2018 A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 SUPERFAMILY SSF50331 250 339 3.27E-9 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 3 339 3.5E-138 T 29-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 Pfam PF00005 ABC transporter 21 163 4.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 Pfam PF08402 TOBE domain 258 336 1.9E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 SUPERFAMILY SSF52540 6 244 1.91E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 SMART SM00382 30 213 5.4E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS24700 8f3bc72d19f8508da74411ad54d7b960 349 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14405 b3c451a171164997688e71213a4a59f2 256 SUPERFAMILY SSF52540 3 246 9.21E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14405 b3c451a171164997688e71213a4a59f2 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 2.3E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A616_RS14405 b3c451a171164997688e71213a4a59f2 256 SMART SM00382 29 225 1.2E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14405 b3c451a171164997688e71213a4a59f2 256 Pfam PF00005 ABC transporter 21 176 2.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14405 b3c451a171164997688e71213a4a59f2 256 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14405 b3c451a171164997688e71213a4a59f2 256 Gene3D G3DSA:3.40.50.300 1 254 6.3E-57 T 29-03-2018 A616_RS28455 0cdd7a44dd2c0083ea6417065738d8b9 125 SUPERFAMILY SSF46785 11 117 3.11E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28455 0cdd7a44dd2c0083ea6417065738d8b9 125 Gene3D G3DSA:1.10.10.10 23 119 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28455 0cdd7a44dd2c0083ea6417065738d8b9 125 Pfam PF01638 HxlR-like helix-turn-helix 27 111 9.5E-32 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 91 106 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 Pfam PF01235 Sodium:alanine symporter family 52 448 3.0E-161 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 PRINTS PR00175 Sodium/alanine symporter signature 405 425 6.0E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 PRINTS PR00175 Sodium/alanine symporter signature 209 228 6.0E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 PRINTS PR00175 Sodium/alanine symporter signature 300 318 6.0E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 PRINTS PR00175 Sodium/alanine symporter signature 181 199 6.0E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 PRINTS PR00175 Sodium/alanine symporter signature 345 367 6.0E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 PRINTS PR00175 Sodium/alanine symporter signature 91 113 6.0E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS15160 9e0a1c3a401847113b129d9221b66ace 471 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 436 4.2E-159 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A616_RS24100 3ae9feb62910e1e13de66dc760205fe7 287 SMART SM00530 13 85 2.1E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS24100 3ae9feb62910e1e13de66dc760205fe7 287 Pfam PF13560 Helix-turn-helix domain 32 88 2.7E-18 T 29-03-2018 A616_RS24100 3ae9feb62910e1e13de66dc760205fe7 287 SUPERFAMILY SSF47413 32 84 1.56E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS24100 3ae9feb62910e1e13de66dc760205fe7 287 Gene3D G3DSA:1.10.260.40 1 95 6.3E-16 T 29-03-2018 A616_RS30010 9435352836b2647f64e843720bb74712 151 Pfam PF02502 Ribose/Galactose Isomerase 3 140 3.5E-59 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A616_RS30010 9435352836b2647f64e843720bb74712 151 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 6.6E-61 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A616_RS30010 9435352836b2647f64e843720bb74712 151 SUPERFAMILY SSF89623 1 144 2.09E-61 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A616_RS30010 9435352836b2647f64e843720bb74712 151 PIRSF PIRSF005384 1 147 4.9E-60 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A616_RS30010 9435352836b2647f64e843720bb74712 151 Gene3D G3DSA:3.40.1400.10 1 151 1.4E-71 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A616_RS30010 9435352836b2647f64e843720bb74712 151 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 6.9E-55 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 A616_RS30650 2fa7dc3e7124e3f221c6a8339b186e03 427 Pfam PF12710 haloacid dehalogenase-like hydrolase 255 358 4.0E-9 T 29-03-2018 A616_RS30650 2fa7dc3e7124e3f221c6a8339b186e03 427 Gene3D G3DSA:3.40.50.1000 58 374 2.2E-7 T 29-03-2018 IPR023214 HAD-like domain A616_RS30650 2fa7dc3e7124e3f221c6a8339b186e03 427 SUPERFAMILY SSF56784 35 107 5.5E-30 T 29-03-2018 IPR023214 HAD-like domain A616_RS30650 2fa7dc3e7124e3f221c6a8339b186e03 427 SUPERFAMILY SSF56784 250 367 5.5E-30 T 29-03-2018 IPR023214 HAD-like domain A616_RS30650 2fa7dc3e7124e3f221c6a8339b186e03 427 SUPERFAMILY SSF56784 135 216 5.5E-30 T 29-03-2018 IPR023214 HAD-like domain A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 SUPERFAMILY SSF52540 69 356 8.58E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 Pfam PF03880 DbpA RNA binding domain 449 519 2.4E-23 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 SMART SM00490 253 334 3.5E-36 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 Pfam PF00271 Helicase conserved C-terminal domain 226 334 3.3E-31 T 29-03-2018 IPR001650 Helicase, C-terminal A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 SMART SM00487 21 217 3.7E-65 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 Gene3D G3DSA:3.40.50.300 222 478 2.0E-48 T 29-03-2018 A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 Pfam PF00270 DEAD/DEAH box helicase 27 191 3.0E-51 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A616_RS19625 57296306413b48f31166b9b16fa40cf3 529 Gene3D G3DSA:3.40.50.300 1 221 1.7E-62 T 29-03-2018 A616_RS29410 a1fcde84d36f2408a2e1385bb43d0aa1 350 SMART SM00471 129 265 4.0E-11 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS29410 a1fcde84d36f2408a2e1385bb43d0aa1 350 TIGRFAM TIGR00277 HDIG: HDIG domain 131 214 2.5E-9 T 29-03-2018 IPR006675 HDIG domain A616_RS29410 a1fcde84d36f2408a2e1385bb43d0aa1 350 Pfam PF01966 HD domain 133 255 1.8E-20 T 29-03-2018 IPR006674 HD domain A616_RS29410 a1fcde84d36f2408a2e1385bb43d0aa1 350 SUPERFAMILY SSF109604 122 295 1.17E-36 T 29-03-2018 A616_RS29410 a1fcde84d36f2408a2e1385bb43d0aa1 350 Gene3D G3DSA:1.10.3210.10 78 298 2.8E-41 T 29-03-2018 A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 18 226 1.2E-75 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 Gene3D G3DSA:2.40.100.10 110 244 3.8E-53 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 22 234 1.2E-75 T 29-03-2018 IPR010016 KipI family A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 Gene3D G3DSA:3.30.1360.40 5 106 1.6E-21 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 SUPERFAMILY SSF160467 19 117 3.92E-18 T 29-03-2018 A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 SUPERFAMILY SSF50891 112 242 7.21E-50 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS14675 c9564e2f6f24ceab3d14e107a8229722 249 SMART SM00796 17 226 7.3E-100 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A616_RS29580 5ec462a559ab1c97bb7e877c64083965 163 SUPERFAMILY SSF140566 1 133 3.14E-17 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A616_RS29580 5ec462a559ab1c97bb7e877c64083965 163 Pfam PF05130 FlgN protein 1 145 3.6E-24 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A616_RS29580 5ec462a559ab1c97bb7e877c64083965 163 Gene3D G3DSA:1.20.58.300 1 134 1.4E-25 T 29-03-2018 A616_RS26680 6c3067b6408a9b283e90c4480d0a789b 179 Gene3D G3DSA:2.40.50.140 90 171 2.6E-14 T 29-03-2018 A616_RS26680 6c3067b6408a9b283e90c4480d0a789b 179 Pfam PF01957 NfeD-like C-terminal, partner-binding 44 166 2.6E-7 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain A616_RS19740 360ec8f5a7e11af9cc39fed221dc46c1 198 PIRSF PIRSF001390 1 196 7.1E-81 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B A616_RS19740 360ec8f5a7e11af9cc39fed221dc46c1 198 Pfam PF02441 Flavoprotein 7 135 5.3E-13 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS19740 360ec8f5a7e11af9cc39fed221dc46c1 198 SUPERFAMILY SSF52507 7 192 2.75E-27 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS19740 360ec8f5a7e11af9cc39fed221dc46c1 198 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 7 193 1.9E-88 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B A616_RS19740 360ec8f5a7e11af9cc39fed221dc46c1 198 Gene3D G3DSA:3.40.50.1950 7 197 9.4E-26 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A616_RS28360 3ae01e10c546e62288e6b1d4e24728b0 334 ProSitePatterns PS00869 Renal dipeptidase active site. 104 126 - T 29-03-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A616_RS28360 3ae01e10c546e62288e6b1d4e24728b0 334 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 5 329 4.0E-92 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A616_RS28360 3ae01e10c546e62288e6b1d4e24728b0 334 Gene3D G3DSA:3.20.20.140 2 334 1.1E-94 T 29-03-2018 A616_RS28360 3ae01e10c546e62288e6b1d4e24728b0 334 SUPERFAMILY SSF51556 5 333 4.08E-77 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS05405 5895cea9bb26bf71db5f1f0b2d25ac3c 199 Pfam PF00881 Nitroreductase family 10 178 2.4E-16 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS05405 5895cea9bb26bf71db5f1f0b2d25ac3c 199 Gene3D G3DSA:3.40.109.10 4 199 1.2E-31 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS05405 5895cea9bb26bf71db5f1f0b2d25ac3c 199 SUPERFAMILY SSF55469 4 198 1.96E-71 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS26795 5e4f6dc61484c142ebfe9bcaef71d970 113 SUPERFAMILY SSF55718 10 108 2.21E-5 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS26795 5e4f6dc61484c142ebfe9bcaef71d970 113 Gene3D G3DSA:3.30.1050.10 4 111 2.4E-6 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS26795 5e4f6dc61484c142ebfe9bcaef71d970 113 Pfam PF02036 SCP-2 sterol transfer family 20 108 7.0E-5 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 Gene3D G3DSA:3.40.630.10 3 288 7.1E-64 T 29-03-2018 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 14 389 1.1E-79 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 SUPERFAMILY SSF53187 316 396 4.53E-60 T 29-03-2018 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 SUPERFAMILY SSF53187 9 188 4.53E-60 T 29-03-2018 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 Pfam PF07687 Peptidase dimerisation domain 186 300 4.6E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 115 153 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 Pfam PF01546 Peptidase family M20/M25/M40 80 392 1.2E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 Gene3D G3DSA:3.40.630.10 289 405 3.5E-6 T 29-03-2018 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 79 88 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A616_RS14315 87b353eb4c768d5307b50bb8a4ef2343 405 SUPERFAMILY SSF55031 189 297 3.74E-16 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS10895 3be2bc87a56d410feb23415138fe051b 230 Pfam PF06889 Protein of unknown function (DUF1266) 54 218 1.1E-30 T 29-03-2018 IPR009677 Protein of unknown function DUF1266 A616_RS10895 3be2bc87a56d410feb23415138fe051b 230 Gene3D G3DSA:1.10.3540.10 9 83 0.31 T 29-03-2018 A616_RS28990 9f4d745b25ebbd0c9f1b2dbcaf005122 254 Pfam PF03649 Uncharacterised protein family (UPF0014) 11 246 2.3E-78 T 29-03-2018 IPR005226 UPF0014 family A616_RS28990 9f4d745b25ebbd0c9f1b2dbcaf005122 254 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 10 248 9.8E-78 T 29-03-2018 IPR005226 UPF0014 family A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 Pfam PF00561 alpha/beta hydrolase fold 25 261 2.3E-29 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 Gene3D G3DSA:3.40.50.1820 4 278 5.8E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 6.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 6.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 6.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00412 Epoxide hydrolase signature 31 49 4.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00412 Epoxide hydrolase signature 219 235 4.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00412 Epoxide hydrolase signature 51 66 4.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 PRINTS PR00412 Epoxide hydrolase signature 253 275 4.8E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS24820 2f767529a5ac5df7bbd4a02cf67f81cb 279 SUPERFAMILY SSF53474 13 277 4.39E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 Gene3D G3DSA:3.40.50.720 43 271 2.5E-59 T 29-03-2018 A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 Gene3D G3DSA:3.40.50.720 1 42 8.6E-10 T 29-03-2018 A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 SUPERFAMILY SSF51735 6 269 1.96E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 7.8E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.8E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 7.8E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 7.8E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 7.8E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.8E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 268 3.2E-53 T 29-03-2018 A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 202 0.0058 T 29-03-2018 A616_RS15425 87c16a08505f48bf415ed06f6200aebc 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS21285 165809f997deaae90f98a8c38158c040 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 3.1E-87 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS21285 165809f997deaae90f98a8c38158c040 418 Gene3D G3DSA:3.65.10.10 21 219 9.5E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS21285 165809f997deaae90f98a8c38158c040 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 40.989 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21285 165809f997deaae90f98a8c38158c040 418 Gene3D G3DSA:3.65.10.10 220 418 5.7E-41 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS21285 165809f997deaae90f98a8c38158c040 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 415 2.2E-158 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS21285 165809f997deaae90f98a8c38158c040 418 SUPERFAMILY SSF55205 2 416 4.19E-125 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A616_RS00750 b63aebe06068c82d48d62a326cb6f02a 190 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 3 130 5.9E-27 T 29-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ A616_RS00750 b63aebe06068c82d48d62a326cb6f02a 190 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 12 86 2.8E-17 T 29-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like A616_RS07400 c3abfbba1ff5be2bbe6b7d1cad970db8 186 ProSitePatterns PS00194 Thioredoxin family active site. 76 94 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A616_RS07400 c3abfbba1ff5be2bbe6b7d1cad970db8 186 Gene3D G3DSA:3.40.30.10 34 185 6.5E-44 T 29-03-2018 A616_RS07400 c3abfbba1ff5be2bbe6b7d1cad970db8 186 SUPERFAMILY SSF52833 47 184 2.32E-46 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS07400 c3abfbba1ff5be2bbe6b7d1cad970db8 186 Pfam PF00578 AhpC/TSA family 49 167 3.4E-35 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS19855 3645d28894cbd4a09318f99c47b32298 256 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 27 254 3.0E-87 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A616_RS19855 3645d28894cbd4a09318f99c47b32298 256 SUPERFAMILY SSF64005 24 249 2.75E-92 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A616_RS19855 3645d28894cbd4a09318f99c47b32298 256 Pfam PF01255 Putative undecaprenyl diphosphate synthase 34 254 1.1E-85 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A616_RS19855 3645d28894cbd4a09318f99c47b32298 256 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 200 217 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 A616_RS19855 3645d28894cbd4a09318f99c47b32298 256 Gene3D G3DSA:3.40.1180.10 13 256 1.2E-98 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A616_RS19855 3645d28894cbd4a09318f99c47b32298 256 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 27 255 42.22 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 31 57 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 SMART SM00344 13 118 7.8E-25 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 Pfam PF13404 AsnC-type helix-turn-helix domain 13 54 2.4E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 Pfam PF01037 Lrp/AsnC ligand binding domain 78 143 6.9E-11 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 1.9E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 1.9E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 13 29 1.9E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 SUPERFAMILY SSF46785 13 69 3.29E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 Gene3D G3DSA:1.10.10.10 13 62 7.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 Gene3D G3DSA:3.30.70.920 64 156 2.0E-18 T 29-03-2018 A616_RS03260 11e93a862a8083ed24395633cc0bb326 158 SUPERFAMILY SSF54909 72 150 5.09E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS15365 bc534b83aa981059256e4786f59f7354 635 Pfam PF14864 Alkyl sulfatase C-terminal 516 634 2.2E-25 T 29-03-2018 IPR029229 Alkyl sulfatase, C-terminal A616_RS15365 bc534b83aa981059256e4786f59f7354 635 Gene3D G3DSA:3.30.1050.10 505 634 2.9E-21 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS15365 bc534b83aa981059256e4786f59f7354 635 Pfam PF14863 Alkyl sulfatase dimerisation 365 503 1.9E-56 T 29-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 A616_RS15365 bc534b83aa981059256e4786f59f7354 635 SUPERFAMILY SSF55718 516 634 5.89E-27 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS15365 bc534b83aa981059256e4786f59f7354 635 Pfam PF00753 Metallo-beta-lactamase superfamily 103 318 1.0E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15365 bc534b83aa981059256e4786f59f7354 635 SUPERFAMILY SSF56281 9 505 1.02E-137 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15365 bc534b83aa981059256e4786f59f7354 635 SMART SM00849 107 328 2.3E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS15365 bc534b83aa981059256e4786f59f7354 635 Gene3D G3DSA:3.60.15.10 81 378 4.2E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS30255 c102b5388e54b7edb5829fdffb515026 299 Pfam PF00395 S-layer homology domain 36 76 0.0084 T 29-03-2018 IPR001119 S-layer homology domain A616_RS16840 7783221f26ad4576c790b89f4a7b7234 215 SUPERFAMILY SSF102405 27 201 3.75E-40 T 29-03-2018 A616_RS16840 7783221f26ad4576c790b89f4a7b7234 215 Gene3D G3DSA:3.40.50.450 24 207 6.7E-32 T 29-03-2018 A616_RS16840 7783221f26ad4576c790b89f4a7b7234 215 Pfam PF06908 Protein of unknown function (DUF1273) 29 192 7.3E-26 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 A616_RS01210 79beb80b31e286349b30c3d30baf0fea 228 SUPERFAMILY SSF56784 6 217 3.36E-38 T 29-03-2018 IPR023214 HAD-like domain A616_RS01210 79beb80b31e286349b30c3d30baf0fea 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 189 1.4E-22 T 29-03-2018 IPR023214 HAD-like domain A616_RS01210 79beb80b31e286349b30c3d30baf0fea 228 Gene3D G3DSA:3.40.50.1000 2 41 2.3E-5 T 29-03-2018 IPR023214 HAD-like domain A616_RS01210 79beb80b31e286349b30c3d30baf0fea 228 Gene3D G3DSA:3.40.50.1000 77 226 8.8E-23 T 29-03-2018 IPR023214 HAD-like domain A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 193 218 0.13 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 SUPERFAMILY SSF51161 3 241 1.28E-42 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 Gene3D G3DSA:2.160.10.10 81 237 6.4E-38 T 29-03-2018 A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 Gene3D G3DSA:2.160.10.10 1 80 2.2E-16 T 29-03-2018 A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 166 2.6E-4 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 26 61 1.0E-8 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29660 0f010834ff52608fe2af39d30be7f59f 251 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 80 131 0.0015 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS16435 f67ae2e9bcb44e88970178a48462a04b 234 Gene3D G3DSA:3.60.21.10 1 234 5.8E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS16435 f67ae2e9bcb44e88970178a48462a04b 234 SUPERFAMILY SSF56300 2 221 5.01E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS16435 f67ae2e9bcb44e88970178a48462a04b 234 Pfam PF00149 Calcineurin-like phosphoesterase 2 213 1.6E-16 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS08875 ad4d84469a16b71e2284573dbb6f8916 202 Gene3D G3DSA:2.60.60.30 20 199 3.7E-55 T 29-03-2018 A616_RS08875 ad4d84469a16b71e2284573dbb6f8916 202 Pfam PF02342 TerD domain 4 201 1.7E-75 T 29-03-2018 IPR003325 TerD domain GO:0006950 A616_RS31850 51b14fb6a7c3196b246850bb07940700 220 Pfam PF01965 DJ-1/PfpI family 26 216 3.1E-18 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS31850 51b14fb6a7c3196b246850bb07940700 220 SUPERFAMILY SSF52317 1 218 2.29E-68 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS31850 51b14fb6a7c3196b246850bb07940700 220 Gene3D G3DSA:3.40.50.880 1 220 1.2E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS13375 7395625ad2662743c79eccab7a90daad 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 79 2.5E-16 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS13375 7395625ad2662743c79eccab7a90daad 305 Gene3D G3DSA:1.10.3720.10 31 293 1.8E-46 T 29-03-2018 A616_RS13375 7395625ad2662743c79eccab7a90daad 305 SUPERFAMILY SSF161098 98 304 2.49E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS13375 7395625ad2662743c79eccab7a90daad 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 305 2.5E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS05145 077f8f1a41663b423164ed2a297286ee 163 Pfam PF13420 Acetyltransferase (GNAT) domain 4 156 3.3E-25 T 29-03-2018 A616_RS05145 077f8f1a41663b423164ed2a297286ee 163 Gene3D G3DSA:3.40.630.30 1 163 1.1E-30 T 29-03-2018 A616_RS05145 077f8f1a41663b423164ed2a297286ee 163 SUPERFAMILY SSF55729 1 161 1.41E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS01440 4ed7e38afb6005667f9565d6d5d21535 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.236 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01440 4ed7e38afb6005667f9565d6d5d21535 65 Gene3D G3DSA:1.10.287.310 1 63 1.6E-25 T 29-03-2018 A616_RS01440 4ed7e38afb6005667f9565d6d5d21535 65 Pfam PF00831 Ribosomal L29 protein 5 60 2.7E-25 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01440 4ed7e38afb6005667f9565d6d5d21535 65 SUPERFAMILY SSF46561 1 63 2.22E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01440 4ed7e38afb6005667f9565d6d5d21535 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 6 60 8.3E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS15920 dba2a8670cfe713146cf2715340d804b 478 Gene3D G3DSA:3.40.710.10 6 369 2.9E-83 T 29-03-2018 A616_RS15920 dba2a8670cfe713146cf2715340d804b 478 SUPERFAMILY SSF56601 6 360 1.88E-86 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS15920 dba2a8670cfe713146cf2715340d804b 478 Pfam PF00144 Beta-lactamase 15 359 2.4E-65 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS09150 c9e91921de24210b47334010ee5112a7 297 SUPERFAMILY SSF103481 183 284 1.44E-9 T 29-03-2018 A616_RS09150 c9e91921de24210b47334010ee5112a7 297 Pfam PF00892 EamA-like transporter family 147 281 3.8E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS09150 c9e91921de24210b47334010ee5112a7 297 Pfam PF00892 EamA-like transporter family 4 136 1.6E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS09150 c9e91921de24210b47334010ee5112a7 297 SUPERFAMILY SSF103481 38 139 1.96E-16 T 29-03-2018 A616_RS13305 81b6008e50dd6543b7927cfbd6698710 399 SUPERFAMILY SSF55909 190 307 4.91E-5 T 29-03-2018 A616_RS13305 81b6008e50dd6543b7927cfbd6698710 399 Pfam PF12982 Protein of unknown function (DUF3866) 41 358 6.4E-115 T 29-03-2018 IPR024479 Protein of unknown function DUF3866 A616_RS29035 143558b0be341b607e26c5576d94574d 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 41.402 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29035 143558b0be341b607e26c5576d94574d 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29035 143558b0be341b607e26c5576d94574d 252 Pfam PF00121 Triosephosphate isomerase 5 246 5.1E-95 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29035 143558b0be341b607e26c5576d94574d 252 Gene3D G3DSA:3.20.20.70 1 252 7.7E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS29035 143558b0be341b607e26c5576d94574d 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.1E-57 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29035 143558b0be341b607e26c5576d94574d 252 SUPERFAMILY SSF51351 1 247 1.7E-95 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS30140 57a71eb3b4398bb3221f7be7f7249721 175 SUPERFAMILY SSF52833 56 163 2.17E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS30140 57a71eb3b4398bb3221f7be7f7249721 175 Pfam PF00578 AhpC/TSA family 60 151 1.2E-4 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS30140 57a71eb3b4398bb3221f7be7f7249721 175 Gene3D G3DSA:3.40.30.10 38 166 4.7E-10 T 29-03-2018 A616_RS31855 0aa975e6007d4a77ae580bf76457f021 402 SUPERFAMILY SSF103473 12 398 1.06E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS31855 0aa975e6007d4a77ae580bf76457f021 402 Gene3D G3DSA:1.20.1250.20 13 207 5.1E-28 T 29-03-2018 A616_RS31855 0aa975e6007d4a77ae580bf76457f021 402 Gene3D G3DSA:1.20.1250.20 208 402 5.1E-19 T 29-03-2018 A616_RS31855 0aa975e6007d4a77ae580bf76457f021 402 Pfam PF07690 Major Facilitator Superfamily 28 358 8.5E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS09685 8e3b5113e38cb6bfbfcbdf2b384edbc2 315 Gene3D G3DSA:1.20.1260.10 42 113 9.2E-4 T 29-03-2018 IPR012347 Ferritin-related A616_RS09685 8e3b5113e38cb6bfbfcbdf2b384edbc2 315 SUPERFAMILY SSF53335 60 303 2.84E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS09685 8e3b5113e38cb6bfbfcbdf2b384edbc2 315 Gene3D G3DSA:3.40.50.150 114 305 2.4E-35 T 29-03-2018 A616_RS09685 8e3b5113e38cb6bfbfcbdf2b384edbc2 315 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 65 304 2.3E-46 T 29-03-2018 A616_RS00770 9826dd703943c10c285aba146da89a59 253 Gene3D G3DSA:3.40.50.410 127 243 9.8E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS00770 9826dd703943c10c285aba146da89a59 253 Pfam PF00092 von Willebrand factor type A domain 7 64 3.0E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS00770 9826dd703943c10c285aba146da89a59 253 SUPERFAMILY SSF53300 132 225 2.08E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS00770 9826dd703943c10c285aba146da89a59 253 Gene3D G3DSA:3.40.50.410 2 94 6.0E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS00770 9826dd703943c10c285aba146da89a59 253 Pfam PF13519 von Willebrand factor type A domain 134 226 1.4E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS00770 9826dd703943c10c285aba146da89a59 253 SUPERFAMILY SSF53300 5 70 6.33E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 6.1E-43 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 6.7E-156 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 1.7E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 1.7E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.7E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 1.7E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.7E-29 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 PIRSF PIRSF000102 2 312 2.5E-104 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 Gene3D G3DSA:3.40.50.720 7 149 3.6E-38 T 29-03-2018 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 307 2.4E-26 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 Gene3D G3DSA:3.90.110.10 150 312 2.9E-47 T 29-03-2018 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 SUPERFAMILY SSF56327 150 310 7.93E-52 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 SUPERFAMILY SSF51735 7 147 8.24E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS08000 ddd58f934bd6b6fd4fb671a305ad2155 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 46.706 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Pfam PF02743 Cache domain 34 283 6.9E-27 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Gene3D G3DSA:3.30.450.20 179 297 7.3E-22 T 29-03-2018 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 632 7.6E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Gene3D G3DSA:1.10.287.950 345 432 5.4E-8 T 29-03-2018 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Gene3D G3DSA:3.30.450.20 60 178 5.9E-19 T 29-03-2018 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Pfam PF00672 HAMP domain 322 371 2.1E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 SMART SM00304 322 375 3.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 Gene3D G3DSA:1.10.287.950 433 680 1.4E-58 T 29-03-2018 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 SUPERFAMILY SSF58104 410 678 7.72E-83 T 29-03-2018 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 SUPERFAMILY SSF58104 343 377 7.72E-83 T 29-03-2018 A616_RS23740 f58031009f7a39f15237447a641a02d5 680 SMART SM00283 404 679 2.9E-92 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS22055 0778e41be71d5ff79978a4eed437a8b3 271 Pfam PF08241 Methyltransferase domain 49 146 3.3E-17 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS22055 0778e41be71d5ff79978a4eed437a8b3 271 Gene3D G3DSA:3.40.50.150 15 214 1.9E-29 T 29-03-2018 A616_RS22055 0778e41be71d5ff79978a4eed437a8b3 271 SUPERFAMILY SSF53335 33 212 5.23E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS11985 eed8e6e8f101597fd3ac2e26d228bace 158 SUPERFAMILY SSF55729 3 149 1.56E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11985 eed8e6e8f101597fd3ac2e26d228bace 158 Pfam PF13673 Acetyltransferase (GNAT) domain 50 142 3.0E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS11985 eed8e6e8f101597fd3ac2e26d228bace 158 Gene3D G3DSA:3.40.630.30 2 157 9.9E-18 T 29-03-2018 A616_RS27795 b25f2bf0b8166f02ae5cc6499d0ca1e3 310 Gene3D G3DSA:3.20.20.150 25 307 2.4E-21 T 29-03-2018 A616_RS27795 b25f2bf0b8166f02ae5cc6499d0ca1e3 310 SUPERFAMILY SSF51658 42 268 9.3E-20 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS27795 b25f2bf0b8166f02ae5cc6499d0ca1e3 310 Pfam PF01261 Xylose isomerase-like TIM barrel 52 229 1.7E-10 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS27155 b2b58978aaeefa93b50167d9286f6130 94 Pfam PF02553 Cobalt transport protein component CbiN 6 72 5.0E-32 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 A616_RS27155 b2b58978aaeefa93b50167d9286f6130 94 TIGRFAM TIGR01165 cbiN: cobalt transport protein 8 87 2.2E-32 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 A616_RS27155 b2b58978aaeefa93b50167d9286f6130 94 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 94 44.692 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 A616_RS23790 c60aad82b24e9bce68202f8524b8c7cb 312 Pfam PF03547 Membrane transport protein 12 154 1.4E-15 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 SUPERFAMILY SSF46689 182 233 1.52E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 SMART SM00342 199 282 8.7E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 Pfam PF12833 Helix-turn-helix domain 205 283 8.0E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 Gene3D G3DSA:1.10.10.60 189 237 9.3E-11 T 29-03-2018 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 236 278 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 Gene3D G3DSA:1.10.10.60 238 285 4.3E-13 T 29-03-2018 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 SUPERFAMILY SSF46689 236 284 4.48E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 266 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 282 1.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS07905 af9ae9bdca54256b2a0fddce4cba75e0 285 Gene3D G3DSA:2.60.120.280 3 188 6.0E-5 T 29-03-2018 A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 7.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 7.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 7.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 7.2E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 Pfam PF01047 MarR family 40 95 3.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 Gene3D G3DSA:1.10.10.10 9 155 1.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 SUPERFAMILY SSF46785 16 148 2.32E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04470 5ee17dc6f1b5f8d186a2f092652ff90b 156 SMART SM00347 31 130 2.4E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 Gene3D G3DSA:1.10.10.60 397 467 1.2E-10 T 29-03-2018 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 SUPERFAMILY SSF55785 11 112 1.12E-9 T 29-03-2018 IPR000014 PAS domain A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 Gene3D G3DSA:3.30.450.20 2 148 1.1E-10 T 29-03-2018 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 Gene3D G3DSA:3.40.50.300 149 325 6.9E-25 T 29-03-2018 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 SUPERFAMILY SSF46689 366 464 1.16E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 Pfam PF00158 Sigma-54 interaction domain 156 321 1.1E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 124 6.8E-7 T 29-03-2018 IPR000014 PAS domain A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 177 190 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 SUPERFAMILY SSF52540 154 396 1.68E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 SMART SM00382 173 317 5.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A616_RS31470 e743c855aeb86ee36540d73d1555907c 467 Gene3D G3DSA:1.10.8.60 326 396 4.0E-24 T 29-03-2018 A616_RS17680 b4d84979007fcb871b308746591810b5 99 Gene3D G3DSA:3.40.50.360 1 97 1.5E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS17680 b4d84979007fcb871b308746591810b5 99 SUPERFAMILY SSF52218 1 92 7.96E-21 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS17680 b4d84979007fcb871b308746591810b5 99 Pfam PF02525 Flavodoxin-like fold 1 88 2.2E-19 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS26325 8c087768c11285dd6c565668ff7ca32a 119 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A616_RS26325 8c087768c11285dd6c565668ff7ca32a 119 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 2.3E-39 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A616_RS26325 8c087768c11285dd6c565668ff7ca32a 119 Gene3D G3DSA:2.60.300.12 1 110 9.4E-41 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS26325 8c087768c11285dd6c565668ff7ca32a 119 SUPERFAMILY SSF89360 1 95 3.73E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS26325 8c087768c11285dd6c565668ff7ca32a 119 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 1.2E-21 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS05705 287e5d49566248b54da45e36b26172fe 296 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 182 293 8.3E-34 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF A616_RS11235 40ded076281842c6a4a33c32e5084d43 118 SUPERFAMILY SSF81301 5 114 6.54E-41 T 29-03-2018 A616_RS11235 40ded076281842c6a4a33c32e5084d43 118 Pfam PF02410 Ribosomal silencing factor during starvation 12 106 8.5E-28 T 29-03-2018 A616_RS11235 40ded076281842c6a4a33c32e5084d43 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 5 107 25.996 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A616_RS11235 40ded076281842c6a4a33c32e5084d43 118 Gene3D G3DSA:3.30.460.10 3 117 1.4E-34 T 29-03-2018 A616_RS11235 40ded076281842c6a4a33c32e5084d43 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 106 1.0E-37 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A616_RS31185 b604d6a16e30c3485c41d1bfdcb28b7d 252 Pfam PF00005 ABC transporter 18 164 1.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS31185 b604d6a16e30c3485c41d1bfdcb28b7d 252 Gene3D G3DSA:3.40.50.300 1 245 3.6E-64 T 29-03-2018 A616_RS31185 b604d6a16e30c3485c41d1bfdcb28b7d 252 SMART SM00382 26 213 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31185 b604d6a16e30c3485c41d1bfdcb28b7d 252 SUPERFAMILY SSF52540 1 228 6.6E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20935 ddf7d32eee49d7312aa7fff95bbf3691 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 117 2.0E-27 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS20935 ddf7d32eee49d7312aa7fff95bbf3691 329 SUPERFAMILY SSF51735 2 147 1.5E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20935 ddf7d32eee49d7312aa7fff95bbf3691 329 Gene3D G3DSA:3.40.50.720 1 145 4.1E-38 T 29-03-2018 A616_RS20935 ddf7d32eee49d7312aa7fff95bbf3691 329 SUPERFAMILY SSF55347 126 288 2.94E-25 T 29-03-2018 A616_RS20935 ddf7d32eee49d7312aa7fff95bbf3691 329 Gene3D G3DSA:3.30.360.10 146 326 6.2E-28 T 29-03-2018 A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 SUPERFAMILY SSF55781 69 241 3.2E-36 T 29-03-2018 IPR029016 GAF domain-like A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 Pfam PF01614 Bacterial transcriptional regulator 121 238 3.0E-21 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 Gene3D G3DSA:3.30.450.40 71 243 8.6E-35 T 29-03-2018 IPR029016 GAF domain-like A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 SMART SM00346 2 93 6.0E-18 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 SUPERFAMILY SSF46785 2 76 4.52E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 Gene3D G3DSA:1.10.10.10 1 64 2.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25010 90a6278105585fbc0bf3ceef7ecbe346 243 Pfam PF09339 IclR helix-turn-helix domain 4 56 2.5E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A616_RS08675 a5fcd9d6b5890497e1a3e369acd59c7d 505 PIRSF PIRSF026631 1 505 4.8E-92 T 29-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 A616_RS08675 a5fcd9d6b5890497e1a3e369acd59c7d 505 Pfam PF03703 Bacterial PH domain 417 495 3.7E-8 T 29-03-2018 IPR005182 Domain of unknown function DUF304 A616_RS08675 a5fcd9d6b5890497e1a3e369acd59c7d 505 Pfam PF03703 Bacterial PH domain 263 343 1.5E-11 T 29-03-2018 IPR005182 Domain of unknown function DUF304 A616_RS08675 a5fcd9d6b5890497e1a3e369acd59c7d 505 Pfam PF03703 Bacterial PH domain 64 143 2.2E-14 T 29-03-2018 IPR005182 Domain of unknown function DUF304 A616_RS00345 d4e90f3a84e7f91b8dbb8f8099cd2c51 132 Pfam PF01381 Helix-turn-helix 22 77 3.7E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS00345 d4e90f3a84e7f91b8dbb8f8099cd2c51 132 SUPERFAMILY SSF47413 14 84 2.53E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS00345 d4e90f3a84e7f91b8dbb8f8099cd2c51 132 SMART SM00530 21 77 7.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS00345 d4e90f3a84e7f91b8dbb8f8099cd2c51 132 Gene3D G3DSA:1.10.260.40 11 130 8.1E-22 T 29-03-2018 A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Gene3D G3DSA:3.10.20.30 487 538 0.27 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Gene3D G3DSA:3.10.20.30 616 716 0.03 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 SUPERFAMILY SSF53067 9 203 4.66E-24 T 29-03-2018 A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Gene3D G3DSA:3.30.420.40 214 352 1.5E-21 T 29-03-2018 A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 SMART SM00842 10 207 9.7E-47 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 SUPERFAMILY SSF53067 214 385 2.47E-28 T 29-03-2018 A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Pfam PF14450 Cell division protein FtsA 218 380 8.1E-12 T 29-03-2018 A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Gene3D G3DSA:3.10.20.30 355 486 1.1E-5 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Pfam PF11104 Type IV pilus assembly protein PilM; 13 99 7.2E-7 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM A616_RS22995 2a1d348da7516d474dfed26e567b6ad4 718 Gene3D G3DSA:3.30.420.40 4 198 4.8E-27 T 29-03-2018 A616_RS21610 2f390a5ea63c364f5eb114619fd52dab 193 Gene3D G3DSA:1.10.10.10 13 148 1.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21610 2f390a5ea63c364f5eb114619fd52dab 193 SMART SM00347 40 138 7.7E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS21610 2f390a5ea63c364f5eb114619fd52dab 193 Pfam PF01047 MarR family 50 106 2.0E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS21610 2f390a5ea63c364f5eb114619fd52dab 193 SUPERFAMILY SSF46785 33 134 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16370 8e2b7dcb316e9265eee21312fd9d93a4 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 9 63 7.4E-24 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A616_RS16370 8e2b7dcb316e9265eee21312fd9d93a4 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 24 33 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS16370 8e2b7dcb316e9265eee21312fd9d93a4 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 42 56 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS08065 d6b80c7b64be93ca7ab847bdd31bf694 260 SUPERFAMILY SSF88713 35 255 5.34E-70 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS08065 d6b80c7b64be93ca7ab847bdd31bf694 260 Gene3D G3DSA:3.20.20.370 28 258 4.9E-83 T 29-03-2018 A616_RS08065 d6b80c7b64be93ca7ab847bdd31bf694 260 Pfam PF04748 Divergent polysaccharide deacetylase 41 254 5.4E-76 T 29-03-2018 IPR006837 Divergent polysaccharide deacetylase A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 Pfam PF01368 DHH family 337 490 2.7E-21 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 Pfam PF02272 DHHA1 domain 512 641 1.6E-12 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 SUPERFAMILY SSF64182 335 633 3.14E-64 T 29-03-2018 A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 PIRSF PIRSF026583 1 645 1.5E-235 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 Gene3D G3DSA:3.30.70.270 154 301 9.9E-9 T 29-03-2018 A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 Gene3D G3DSA:3.90.1640.10 314 530 7.6E-48 T 29-03-2018 A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 SUPERFAMILY SSF55073 161 294 8.63E-6 T 29-03-2018 IPR029787 Nucleotide cyclase A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 SMART SM00267 134 297 5.8E-4 T 29-03-2018 IPR000160 GGDEF domain A616_RS32165 a2086799a01d583f3e97308dcc32a6b0 645 Gene3D G3DSA:3.30.450.20 51 153 2.5E-4 T 29-03-2018 A616_RS06755 22f0c63aebfb99f040986182ec16ddbc 64 Pfam PF10960 BhlA holin family 1 57 6.9E-16 T 29-03-2018 IPR024405 Prophage protein BhlA/UviB A616_RS06755 22f0c63aebfb99f040986182ec16ddbc 64 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 1 36 6.0E-7 T 29-03-2018 IPR024405 Prophage protein BhlA/UviB A616_RS09930 37c7e7c6ca631a2670fafcfca595525f 324 Gene3D G3DSA:3.40.50.720 1 130 4.5E-37 T 29-03-2018 A616_RS09930 37c7e7c6ca631a2670fafcfca595525f 324 SUPERFAMILY SSF55347 124 292 1.31E-35 T 29-03-2018 A616_RS09930 37c7e7c6ca631a2670fafcfca595525f 324 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 118 1.6E-26 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS09930 37c7e7c6ca631a2670fafcfca595525f 324 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 223 1.2E-8 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A616_RS09930 37c7e7c6ca631a2670fafcfca595525f 324 Gene3D G3DSA:3.30.360.10 131 324 1.4E-50 T 29-03-2018 A616_RS09930 37c7e7c6ca631a2670fafcfca595525f 324 SUPERFAMILY SSF51735 2 147 7.88E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26250 ec114c4b15baacfa0e59b16441c07e75 211 Gene3D G3DSA:2.40.40.10 26 188 6.3E-33 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A616_RS26250 ec114c4b15baacfa0e59b16441c07e75 211 SUPERFAMILY SSF50685 114 158 1.33E-6 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A616_RS26250 ec114c4b15baacfa0e59b16441c07e75 211 Pfam PF06725 3D domain 116 177 9.3E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A616_RS25850 64e77eecccbfccbce72684328e10e2d1 381 SUPERFAMILY SSF55729 198 360 5.55E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25850 64e77eecccbfccbce72684328e10e2d1 381 Pfam PF13480 Acetyltransferase (GNAT) domain 198 322 5.5E-6 T 29-03-2018 A616_RS25850 64e77eecccbfccbce72684328e10e2d1 381 Gene3D G3DSA:3.40.630.30 190 341 1.2E-6 T 29-03-2018 A616_RS13055 adaa6c272bb3b651464fda1c97c80ad7 172 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 172 7.7E-51 T 29-03-2018 IPR014198 Stage III sporulation protein AB A616_RS13055 adaa6c272bb3b651464fda1c97c80ad7 172 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 172 1.2E-54 T 29-03-2018 IPR014198 Stage III sporulation protein AB A616_RS13055 adaa6c272bb3b651464fda1c97c80ad7 172 PIRSF PIRSF021435 1 172 1.6E-53 T 29-03-2018 IPR014198 Stage III sporulation protein AB A616_RS06830 ad8d1918628ff0cb1f5a1e615e668ae7 162 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 2 146 4.9E-49 T 29-03-2018 IPR018697 Protein of unknown function DUF2199 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 8 625 6.8E-201 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 419 441 2.0E-23 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 512 533 2.0E-23 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 266 288 2.0E-23 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 2.0E-23 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 361 383 2.0E-23 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 2.0E-23 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 67 122 5.9E-20 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 226 247 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 420 439 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 316 328 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 248 274 4.6E-63 T 29-03-2018 A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 Pfam PF01010 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus 447 578 4.1E-8 T 29-03-2018 IPR002128 NADH:ubiquinone/plastoquinone oxidoreductase, chloroplast chain 5, C-terminal A616_RS29845 d6b257e2c86bd263ff7799d3c0280028 637 Pfam PF00361 Proton-conducting membrane transporter 135 427 2.0E-89 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS06315 2ed97c95e6b618b4efba0877205d1ea7 188 Gene3D G3DSA:3.90.1530.10 1 95 8.7E-13 T 29-03-2018 A616_RS06315 2ed97c95e6b618b4efba0877205d1ea7 188 SUPERFAMILY SSF110849 1 109 1.2E-12 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS06315 2ed97c95e6b618b4efba0877205d1ea7 188 Pfam PF02195 ParB-like nuclease domain 5 93 9.5E-8 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS06315 2ed97c95e6b618b4efba0877205d1ea7 188 SMART SM00470 4 94 0.0012 T 29-03-2018 IPR003115 ParB/Sulfiredoxin A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 SUPERFAMILY SSF64518 1 273 1.57E-85 T 29-03-2018 A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 2.5E-42 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 PRINTS PR00207 Flagellin signature 35 52 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 PRINTS PR00207 Flagellin signature 74 93 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 PRINTS PR00207 Flagellin signature 110 133 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 188 272 3.5E-29 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS29545 25e3bdd99981c2af7ea0407057ab03e0 273 Gene3D G3DSA:1.20.1330.10 38 245 4.3E-68 T 29-03-2018 A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 5.0E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 Pfam PF08359 YsiA-like protein, C-terminal region 66 190 1.7E-6 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 Gene3D G3DSA:1.10.357.10 55 199 5.4E-21 T 29-03-2018 A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 SUPERFAMILY SSF46689 7 85 1.13E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 SUPERFAMILY SSF48498 80 193 1.72E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS14830 9428addaf188e5a5232a8a6a2c495051 218 Gene3D G3DSA:1.10.10.60 7 54 4.6E-17 T 29-03-2018 A616_RS12870 512ba0d4f8fe8fff4b616195ace08ab4 221 SUPERFAMILY SSF52540 4 209 1.66E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12870 512ba0d4f8fe8fff4b616195ace08ab4 221 Pfam PF00005 ABC transporter 16 154 1.6E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12870 512ba0d4f8fe8fff4b616195ace08ab4 221 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS12870 512ba0d4f8fe8fff4b616195ace08ab4 221 Gene3D G3DSA:3.40.50.300 2 216 2.6E-59 T 29-03-2018 A616_RS12870 512ba0d4f8fe8fff4b616195ace08ab4 221 SMART SM00382 22 204 3.7E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS00960 c0f3297f820ae014323a3073a46997a5 298 Pfam PF00482 Type II secretion system (T2SS), protein F 125 251 3.5E-9 T 29-03-2018 IPR018076 Type II secretion system F domain A616_RS05420 960c2152f003b477e598a20e3d612842 220 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 10 214 2.1E-71 T 29-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 A616_RS05420 960c2152f003b477e598a20e3d612842 220 Gene3D G3DSA:3.40.50.1580 12 220 8.1E-42 T 29-03-2018 A616_RS05420 960c2152f003b477e598a20e3d612842 220 Pfam PF01048 Phosphorylase superfamily 24 212 1.5E-18 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS05420 960c2152f003b477e598a20e3d612842 220 Hamap MF_00991 Futalosine hydrolase [mqnB]. 23 217 23.114 T 29-03-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 A616_RS05420 960c2152f003b477e598a20e3d612842 220 SUPERFAMILY SSF53167 23 199 1.44E-33 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS31145 161d51112df866418621dcca57ad9a2d 276 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 29 276 8.7E-74 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS31145 161d51112df866418621dcca57ad9a2d 276 Gene3D G3DSA:3.40.190.10 40 133 2.5E-21 T 29-03-2018 A616_RS31145 161d51112df866418621dcca57ad9a2d 276 PIRSF PIRSF002854 1 276 4.6E-100 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS31145 161d51112df866418621dcca57ad9a2d 276 Gene3D G3DSA:3.40.190.10 134 276 1.3E-52 T 29-03-2018 A616_RS31145 161d51112df866418621dcca57ad9a2d 276 Pfam PF03180 NLPA lipoprotein 41 276 4.3E-94 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS31145 161d51112df866418621dcca57ad9a2d 276 SUPERFAMILY SSF53850 40 276 1.13E-83 T 29-03-2018 A616_RS26330 d24d56580edc28a1717d3c7e98b3757c 73 Pfam PF09388 Spo0E like sporulation regulatory protein 5 44 3.5E-9 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A616_RS26330 d24d56580edc28a1717d3c7e98b3757c 73 SUPERFAMILY SSF140500 3 48 7.46E-9 T 29-03-2018 A616_RS07900 60c5a543b0471b47d640ffa26b943922 429 Pfam PF07690 Major Facilitator Superfamily 23 373 3.6E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS07900 60c5a543b0471b47d640ffa26b943922 429 Gene3D G3DSA:1.20.1250.20 2 201 3.2E-19 T 29-03-2018 A616_RS07900 60c5a543b0471b47d640ffa26b943922 429 Gene3D G3DSA:1.20.1250.20 203 423 2.5E-8 T 29-03-2018 A616_RS07900 60c5a543b0471b47d640ffa26b943922 429 SUPERFAMILY SSF103473 10 414 1.14E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:3.90.1100.10 272 602 1.3E-80 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:3.90.1100.10 20 244 6.2E-58 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:3.90.1100.10 603 670 1.6E-14 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:2.40.270.10 846 1054 5.6E-79 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:2.40.50.100 671 750 5.0E-26 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF00562 RNA polymerase Rpb2, domain 6 674 1068 2.1E-167 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 ProSitePatterns PS01166 RNA polymerases beta chain signature. 921 933 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:3.90.1800.10 1071 1115 8.0E-12 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 206 895 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF04563 RNA polymerase beta subunit 28 453 2.1E-30 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Gene3D G3DSA:2.40.270.10 751 845 3.9E-12 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 SUPERFAMILY SSF64484 377 1154 0.0 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 SUPERFAMILY SSF64484 14 286 0.0 T 29-03-2018 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 1.5E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF04560 RNA polymerase Rpb2, domain 7 1070 1144 2.8E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 613 4.1E-24 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF04561 RNA polymerase Rpb2, domain 2 370 409 7.1E-7 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 291 6.7E-30 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS01345 1e1c4c3f1427f2f87662a3057ad931d7 1179 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1146 12.629 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A616_RS23645 a0bbba23122a20e317ebb9aaddbd5440 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 126 4.3E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS23645 a0bbba23122a20e317ebb9aaddbd5440 132 SUPERFAMILY SSF54593 10 127 2.95E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS23645 a0bbba23122a20e317ebb9aaddbd5440 132 Gene3D G3DSA:3.10.180.10 3 130 1.0E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS05245 4a7967baedf1f5f96bdd7e2a87798f7b 206 Gene3D G3DSA:2.40.10.220 76 205 3.6E-18 T 29-03-2018 A616_RS05245 4a7967baedf1f5f96bdd7e2a87798f7b 206 SUPERFAMILY SSF141371 81 193 5.49E-9 T 29-03-2018 A616_RS05245 4a7967baedf1f5f96bdd7e2a87798f7b 206 Pfam PF07238 PilZ domain 82 192 1.9E-8 T 29-03-2018 IPR009875 PilZ domain GO:0035438 A616_RS08355 1c8c4334255cd6fe99ff7947015aec0c 281 SUPERFAMILY SSF82549 4 281 1.57E-82 T 29-03-2018 A616_RS08355 1c8c4334255cd6fe99ff7947015aec0c 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 279 9.5E-79 T 29-03-2018 IPR003797 DegV A616_RS08355 1c8c4334255cd6fe99ff7947015aec0c 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 6 278 1.0E-84 T 29-03-2018 IPR003797 DegV A616_RS08355 1c8c4334255cd6fe99ff7947015aec0c 281 Gene3D G3DSA:3.30.1180.10 155 280 3.7E-34 T 29-03-2018 A616_RS08355 1c8c4334255cd6fe99ff7947015aec0c 281 Gene3D G3DSA:3.40.50.10170 1 154 2.8E-45 T 29-03-2018 A616_RS00850 3a64cbed707c1f6bca7bcf69ac45a85e 279 Gene3D G3DSA:1.10.3470.10 4 277 7.9E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS00850 3a64cbed707c1f6bca7bcf69ac45a85e 279 SUPERFAMILY SSF81345 4 269 2.75E-35 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS00850 3a64cbed707c1f6bca7bcf69ac45a85e 279 Pfam PF00950 ABC 3 transport family 7 269 4.4E-61 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A616_RS18670 c00e0c9918acc8b492a2f1eb9be2c7a3 196 Gene3D G3DSA:3.40.630.30 1 195 3.9E-26 T 29-03-2018 A616_RS18670 c00e0c9918acc8b492a2f1eb9be2c7a3 196 Pfam PF13302 Acetyltransferase (GNAT) domain 15 151 3.3E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS18670 c00e0c9918acc8b492a2f1eb9be2c7a3 196 SUPERFAMILY SSF55729 6 178 4.25E-40 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS13235 4479881c3d1bc217862c9a4c61e47750 388 Gene3D G3DSA:3.40.50.10240 184 331 4.2E-11 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS13235 4479881c3d1bc217862c9a4c61e47750 388 SUPERFAMILY SSF63999 173 329 2.09E-26 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A616_RS13235 4479881c3d1bc217862c9a4c61e47750 388 Pfam PF12555 Thiamine pyrophosphokinase C terminal 336 386 4.0E-16 T 29-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal A616_RS05460 605e08510116dfa94565f4b12ad575cc 241 Gene3D G3DSA:3.40.30.10 1 216 3.0E-59 T 29-03-2018 A616_RS05460 605e08510116dfa94565f4b12ad575cc 241 Pfam PF01323 DSBA-like thioredoxin domain 2 204 8.4E-51 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A616_RS05460 605e08510116dfa94565f4b12ad575cc 241 SUPERFAMILY SSF52833 1 211 3.86E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS09275 b5ffe20089a0aa50bcdfc308312bbf39 413 SUPERFAMILY SSF51556 68 372 1.73E-70 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS09275 b5ffe20089a0aa50bcdfc308312bbf39 413 Pfam PF07969 Amidohydrolase family 177 402 6.4E-15 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS09275 b5ffe20089a0aa50bcdfc308312bbf39 413 Gene3D G3DSA:3.20.20.140 78 355 6.2E-32 T 29-03-2018 A616_RS09275 b5ffe20089a0aa50bcdfc308312bbf39 413 Gene3D G3DSA:2.30.40.10 3 77 1.0E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09275 b5ffe20089a0aa50bcdfc308312bbf39 413 SUPERFAMILY SSF51338 32 83 1.85E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS08060 e209d3d6a1fbd9dae999c800dd132f27 247 SUPERFAMILY SSF53187 33 221 1.08E-43 T 29-03-2018 A616_RS08060 e209d3d6a1fbd9dae999c800dd132f27 247 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 34 216 9.8E-42 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS08060 e209d3d6a1fbd9dae999c800dd132f27 247 SMART SM00646 107 216 1.4E-16 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS08060 e209d3d6a1fbd9dae999c800dd132f27 247 Gene3D G3DSA:3.40.630.40 29 224 7.4E-50 T 29-03-2018 A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 Gene3D G3DSA:3.30.565.10 172 379 7.7E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 SMART SM00387 285 380 1.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 Pfam PF07730 Histidine kinase 179 247 3.2E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 378 2.5E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 SUPERFAMILY SSF55874 250 377 6.16E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 Pfam PF05384 Sensor protein DegS 11 169 3.8E-59 T 29-03-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 PIRSF PIRSF003169 1 380 4.4E-146 T 29-03-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 1.1E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 1.1E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS29615 bc3b9c14ff58814bd90ed1fd7921534b 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 335 1.1E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS10760 4e7d004881f3d9753399fc34ceea05c4 507 SUPERFAMILY SSF102114 167 478 7.72E-71 T 29-03-2018 A616_RS10760 4e7d004881f3d9753399fc34ceea05c4 507 Gene3D G3DSA:3.20.20.70 118 504 1.3E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS10760 4e7d004881f3d9753399fc34ceea05c4 507 SMART SM00729 171 395 6.1E-48 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A616_RS10760 4e7d004881f3d9753399fc34ceea05c4 507 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 87 487 2.9E-148 T 29-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ A616_RS10760 4e7d004881f3d9753399fc34ceea05c4 507 Pfam PF04055 Radical SAM superfamily 179 352 3.7E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS08905 eb8478f7e78b7bd28d91996a655a4bd0 408 Pfam PF00266 Aminotransferase class-V 37 354 9.5E-31 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS08905 eb8478f7e78b7bd28d91996a655a4bd0 408 SUPERFAMILY SSF53383 12 389 6.6E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS08905 eb8478f7e78b7bd28d91996a655a4bd0 408 PIRSF PIRSF000524 5 408 4.4E-130 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 A616_RS08905 eb8478f7e78b7bd28d91996a655a4bd0 408 Gene3D G3DSA:3.40.640.10 21 282 2.3E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS08905 eb8478f7e78b7bd28d91996a655a4bd0 408 Gene3D G3DSA:3.90.1150.10 283 408 6.9E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 PIRSF PIRSF007519 2 752 3.8E-193 T 29-03-2018 IPR012300 Peptidase M6, InhA A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 SUPERFAMILY SSF55486 250 272 1.16E-14 T 29-03-2018 A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 SUPERFAMILY SSF55486 309 389 1.16E-14 T 29-03-2018 A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 155 446 3.3E-62 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 Gene3D G3DSA:3.40.390.10 183 391 7.2E-5 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 Pfam PF05547 Immune inhibitor A peptidase M6 127 739 1.0E-176 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 A616_RS09990 ab553b54f3bd2d835d7ed79baca8f6b6 753 Gene3D G3DSA:2.60.120.260 427 555 2.8E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 SUPERFAMILY SSF56645 1 242 2.62E-91 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 378 2.3E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 PIRSF PIRSF016578 5 380 2.6E-20 T 29-03-2018 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 SUPERFAMILY SSF47203 227 378 2.74E-62 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 Gene3D G3DSA:2.40.110.10 121 217 6.4E-42 T 29-03-2018 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 Gene3D G3DSA:1.20.140.10 218 380 7.5E-66 T 29-03-2018 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.0E-39 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 Gene3D G3DSA:1.10.540.10 1 120 2.0E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A616_RS30160 92793ccf87ad1db5ae53f941c4e96796 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 4.4E-29 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 Gene3D G3DSA:1.20.1250.20 3 202 3.0E-41 T 29-03-2018 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 Gene3D G3DSA:1.20.1250.20 203 405 1.4E-30 T 29-03-2018 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 Pfam PF00083 Sugar (and other) transporter 250 369 5.3E-10 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 Pfam PF07690 Major Facilitator Superfamily 13 246 1.7E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 PRINTS PR01035 Tetracycline resistance protein signature 17 33 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 PRINTS PR01035 Tetracycline resistance protein signature 107 128 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 PRINTS PR01035 Tetracycline resistance protein signature 137 159 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 PRINTS PR01035 Tetracycline resistance protein signature 342 365 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 PRINTS PR01035 Tetracycline resistance protein signature 80 104 1.8E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS05840 c632c1af641efe4b1ea7b9194f413264 406 SUPERFAMILY SSF103473 5 398 7.46E-77 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS29000 a1a977cbbb69337449764fc21a1091ee 412 Gene3D G3DSA:3.30.1450.10 343 385 0.06 T 29-03-2018 A616_RS29000 a1a977cbbb69337449764fc21a1091ee 412 Gene3D G3DSA:3.30.1450.10 191 245 0.038 T 29-03-2018 A616_RS29000 a1a977cbbb69337449764fc21a1091ee 412 Pfam PF14172 Domain of unknown function (DUF4309) 268 400 1.3E-36 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 A616_RS29000 a1a977cbbb69337449764fc21a1091ee 412 Pfam PF14172 Domain of unknown function (DUF4309) 118 236 3.6E-33 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 A616_RS16680 69daf1e0f90ab0387d83bda64d7bf1c8 280 Gene3D G3DSA:2.40.50.140 182 280 7.7E-4 T 29-03-2018 A616_RS16680 69daf1e0f90ab0387d83bda64d7bf1c8 280 Pfam PF01068 ATP dependent DNA ligase domain 21 191 4.2E-30 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A616_RS16680 69daf1e0f90ab0387d83bda64d7bf1c8 280 Gene3D G3DSA:3.30.470.30 1 137 1.9E-32 T 29-03-2018 A616_RS16680 69daf1e0f90ab0387d83bda64d7bf1c8 280 SUPERFAMILY SSF56091 2 192 2.04E-37 T 29-03-2018 A616_RS16680 69daf1e0f90ab0387d83bda64d7bf1c8 280 Gene3D G3DSA:3.30.1490.70 138 181 2.2E-9 T 29-03-2018 A616_RS23535 b3170d0b7b6df474c20e61a6aa451ef3 413 SUPERFAMILY SSF52440 171 285 4.03E-6 T 29-03-2018 IPR016185 Pre-ATP-grasp domain A616_RS23535 b3170d0b7b6df474c20e61a6aa451ef3 413 SUPERFAMILY SSF56059 19 168 1.01E-46 T 29-03-2018 A616_RS23535 b3170d0b7b6df474c20e61a6aa451ef3 413 SUPERFAMILY SSF56059 273 409 1.01E-46 T 29-03-2018 A616_RS23535 b3170d0b7b6df474c20e61a6aa451ef3 413 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 20 411 3.7E-72 T 29-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain A616_RS30300 68a63a64faa9e08a071067afd6353721 207 Pfam PF13171 Protein of unknown function (DUF4004) 4 199 1.7E-82 T 29-03-2018 IPR025063 Protein of unknown function DUF4004 A616_RS30300 68a63a64faa9e08a071067afd6353721 207 Gene3D G3DSA:1.10.1660.10 2 80 1.1E-6 T 29-03-2018 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 Pfam PF12833 Helix-turn-helix domain 192 270 2.1E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 Gene3D G3DSA:3.40.50.1980 279 373 2.2E-6 T 29-03-2018 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 SUPERFAMILY SSF46689 170 220 9.86E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 Gene3D G3DSA:2.60.120.10 18 230 1.5E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 SMART SM00342 186 269 1.7E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 Gene3D G3DSA:3.40.50.1980 374 538 1.7E-24 T 29-03-2018 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 Pfam PF01497 Periplasmic binding protein 343 509 6.9E-11 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 SUPERFAMILY SSF46689 222 270 1.3E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 SUPERFAMILY SSF51215 14 156 1.31E-6 T 29-03-2018 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 Gene3D G3DSA:1.10.10.60 231 278 8.5E-15 T 29-03-2018 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 SUPERFAMILY SSF53807 266 523 2.2E-31 T 29-03-2018 A616_RS30620 624201ffa12482fb2f1c5fd8c2c22141 548 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 223 265 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS02240 25ad9675422efbf52a536d63a7d36c4c 311 Gene3D G3DSA:3.40.190.100 29 152 1.0E-36 T 29-03-2018 A616_RS02240 25ad9675422efbf52a536d63a7d36c4c 311 Gene3D G3DSA:3.40.190.10 202 308 8.0E-16 T 29-03-2018 A616_RS02240 25ad9675422efbf52a536d63a7d36c4c 311 SUPERFAMILY SSF53850 52 202 6.52E-49 T 29-03-2018 A616_RS02240 25ad9675422efbf52a536d63a7d36c4c 311 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 210 310 1.1E-20 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A616_RS02240 25ad9675422efbf52a536d63a7d36c4c 311 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 49 191 5.6E-43 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 A616_RS02240 25ad9675422efbf52a536d63a7d36c4c 311 SUPERFAMILY SSF53850 205 311 1.55E-27 T 29-03-2018 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 Pfam PF00334 Nucleoside diphosphate kinase 2 136 5.5E-60 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.388 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 SMART SM00562 1 138 2.9E-93 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 SUPERFAMILY SSF54919 1 146 8.77E-62 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 Gene3D G3DSA:3.30.70.141 1 147 1.5E-57 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 5.7E-53 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 5.7E-53 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 5.7E-53 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 5.7E-53 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS13780 4146103c4a88b17e49ad837434dcd756 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 5.7E-53 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A616_RS16205 379c00ba123b21cce1eee0dda8fb07c3 187 SUPERFAMILY SSF52218 1 170 6.21E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS16205 379c00ba123b21cce1eee0dda8fb07c3 187 Pfam PF03358 NADPH-dependent FMN reductase 1 145 4.1E-29 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A616_RS16205 379c00ba123b21cce1eee0dda8fb07c3 187 Gene3D G3DSA:3.40.50.360 1 179 2.7E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS13695 8ccc171f9dcef313a43b2190b234853c 62 Pfam PF10966 Protein of unknown function (DUF2768) 8 61 4.0E-14 T 29-03-2018 IPR020076 Protein of unknown function DUF2768 A616_RS18295 a34fd6ffc81e079490afa31280927a9f 175 Gene3D G3DSA:3.40.630.30 1 175 4.0E-25 T 29-03-2018 A616_RS18295 a34fd6ffc81e079490afa31280927a9f 175 SUPERFAMILY SSF55729 1 155 6.29E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS18295 a34fd6ffc81e079490afa31280927a9f 175 Pfam PF13302 Acetyltransferase (GNAT) domain 7 149 2.2E-30 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS23115 ee85a6d17f82cfff84bf5b051ef8b14f 235 SUPERFAMILY SSF54285 2 79 1.87E-16 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A616_RS23115 ee85a6d17f82cfff84bf5b051ef8b14f 235 Gene3D G3DSA:3.10.20.30 3 79 7.5E-23 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS23115 ee85a6d17f82cfff84bf5b051ef8b14f 235 Gene3D G3DSA:3.90.1170.40 80 221 3.8E-50 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS23115 ee85a6d17f82cfff84bf5b051ef8b14f 235 SUPERFAMILY SSF54690 86 224 9.68E-46 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS23115 ee85a6d17f82cfff84bf5b051ef8b14f 235 Pfam PF02597 ThiS family 5 81 2.3E-15 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A616_RS23115 ee85a6d17f82cfff84bf5b051ef8b14f 235 Pfam PF02391 MoaE protein 89 200 5.5E-37 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 Gene3D G3DSA:1.20.1600.10 104 201 1.5E-6 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 Gene3D G3DSA:1.20.1600.10 202 376 4.6E-15 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 Pfam PF13437 HlyD family secretion protein 271 382 3.9E-15 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 379 394 4.8E-12 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 49 69 4.8E-12 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 282 303 4.8E-12 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 314 338 4.8E-12 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 SUPERFAMILY SSF111369 30 124 1.57E-12 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 Pfam PF13533 Biotin-lipoyl like 40 85 1.2E-10 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 SUPERFAMILY SSF56954 4 29 8.63E-6 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 SUPERFAMILY SSF56954 62 281 8.63E-6 T 29-03-2018 A616_RS27315 f601f6c7be4dbfa74738e7176125a322 396 Gene3D G3DSA:2.40.50.100 37 103 3.5E-14 T 29-03-2018 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 191 2.1E-105 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 111 124 - T 29-03-2018 IPR033135 ClpP, histidine active site A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 PRINTS PR00127 Clp protease catalytic subunit P signature 18 33 1.2E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 PRINTS PR00127 Clp protease catalytic subunit P signature 110 129 1.2E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 PRINTS PR00127 Clp protease catalytic subunit P signature 89 106 1.2E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 PRINTS PR00127 Clp protease catalytic subunit P signature 58 78 1.2E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 PRINTS PR00127 Clp protease catalytic subunit P signature 167 186 1.2E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 Gene3D G3DSA:3.90.226.10 1 193 3.3E-48 T 29-03-2018 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 SUPERFAMILY SSF52096 9 191 1.21E-75 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 89 100 - T 29-03-2018 IPR018215 ClpP, Ser active site A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 2 192 45.114 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS10295 8a743f9a34efdc676870ec532f902a2f 193 Pfam PF00574 Clp protease 11 191 2.2E-90 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 5 419 6.3E-127 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 Gene3D G3DSA:3.65.10.10 19 217 1.1E-54 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 423 4.5E-131 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 SUPERFAMILY SSF55205 1 423 2.45E-136 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 426 33.583 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 Gene3D G3DSA:3.65.10.10 218 425 4.9E-49 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 PIRSF PIRSF000505 1 426 4.3E-119 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A616_RS13845 a6dad905415b83418bdf12bd68fae9dd 426 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 SUPERFAMILY SSF53187 373 547 7.85E-59 T 29-03-2018 A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Pfam PF11741 AMIN domain 237 282 9.6E-6 T 29-03-2018 IPR021731 AMIN domain A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Pfam PF11741 AMIN domain 315 364 3.2E-4 T 29-03-2018 IPR021731 AMIN domain A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 376 544 2.1E-55 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 SMART SM00646 436 544 1.5E-49 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Gene3D G3DSA:3.40.630.40 376 551 1.0E-63 T 29-03-2018 A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Gene3D G3DSA:3.30.457.10 23 63 4.7E-10 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Gene3D G3DSA:3.30.457.10 126 183 4.5E-8 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Gene3D G3DSA:3.30.457.10 200 375 0.013 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Gene3D G3DSA:3.30.457.10 64 125 3.5E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 SUPERFAMILY SSF55383 54 138 1.96E-25 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 Pfam PF07833 Copper amine oxidase N-terminal domain 51 142 8.3E-32 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS02745 289deb01cb2b23e32fc0c3d370878dc4 551 SUPERFAMILY SSF55383 116 182 1.83E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS10705 cb559a094f51bd10458da04af4149ce6 528 PIRSF PIRSF038958 1 521 2.0E-147 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A616_RS10705 cb559a094f51bd10458da04af4149ce6 528 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 5 499 1.5E-134 T 29-03-2018 IPR014249 Sporulation stage V protein B A616_RS10705 cb559a094f51bd10458da04af4149ce6 528 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 364 504 2.5E-19 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A616_RS10705 cb559a094f51bd10458da04af4149ce6 528 Pfam PF01943 Polysaccharide biosynthesis protein 8 309 3.1E-37 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A616_RS29820 b5631b5f8410654d423feceaf2216536 441 Gene3D G3DSA:3.65.10.10 21 222 9.3E-54 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS29820 b5631b5f8410654d423feceaf2216536 441 Gene3D G3DSA:3.65.10.10 223 419 2.3E-53 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS29820 b5631b5f8410654d423feceaf2216536 441 SUPERFAMILY SSF55205 1 416 1.34E-145 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A616_RS29820 b5631b5f8410654d423feceaf2216536 441 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 5.6E-114 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A616_RS29820 b5631b5f8410654d423feceaf2216536 441 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.981 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS29820 b5631b5f8410654d423feceaf2216536 441 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 1.6E-179 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A616_RS30205 418c6151014c9c5c5e2bc06bf9c4c1e4 137 SUPERFAMILY SSF50814 4 135 9.02E-27 T 29-03-2018 IPR012674 Calycin A616_RS30205 418c6151014c9c5c5e2bc06bf9c4c1e4 137 Pfam PF09148 Domain of unknown function (DUF1934) 7 133 1.1E-31 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 A616_RS30205 418c6151014c9c5c5e2bc06bf9c4c1e4 137 Gene3D G3DSA:2.40.128.20 1 137 2.6E-36 T 29-03-2018 IPR012674 Calycin A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 98 3.0E-39 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 Pfam PF02261 Aspartate decarboxylase 2 114 1.8E-54 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 Gene3D G3DSA:2.40.40.20 1 117 8.9E-57 T 29-03-2018 A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 2 120 7.4E-58 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 SUPERFAMILY SSF50692 2 120 1.33E-51 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 75.25 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS13960 ccc97d264af41036ee386a39bbce08e8 127 PIRSF PIRSF006246 1 126 2.6E-55 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A616_RS14410 2c811be93fd56b9469843a6e4c60b7e9 233 Pfam PF00005 ABC transporter 18 161 3.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS14410 2c811be93fd56b9469843a6e4c60b7e9 233 Gene3D G3DSA:3.40.50.300 1 233 1.4E-52 T 29-03-2018 A616_RS14410 2c811be93fd56b9469843a6e4c60b7e9 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14410 2c811be93fd56b9469843a6e4c60b7e9 233 SUPERFAMILY SSF52540 2 227 4.19E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14410 2c811be93fd56b9469843a6e4c60b7e9 233 SMART SM00382 27 233 1.8E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS17620 c03828c7fc9180509543dab72c7a1f27 152 Pfam PF10947 Protein of unknown function (DUF2628) 27 105 3.7E-9 T 29-03-2018 IPR024399 Protein of unknown function DUF2628 A616_RS22185 f409fa006a9452330ffc29dc9c37e8e6 299 SUPERFAMILY SSF51735 9 160 4.9E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22185 f409fa006a9452330ffc29dc9c37e8e6 299 Gene3D G3DSA:3.40.50.720 2 163 2.2E-26 T 29-03-2018 A616_RS22185 f409fa006a9452330ffc29dc9c37e8e6 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 161 5.9E-21 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 A616_RS22185 f409fa006a9452330ffc29dc9c37e8e6 299 PIRSF PIRSF000103 2 298 1.2E-30 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A616_RS22185 f409fa006a9452330ffc29dc9c37e8e6 299 Gene3D G3DSA:1.10.1040.10 165 297 1.5E-7 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS29495 a03531b6de03ba825cd31f8df7c0bd88 222 Gene3D G3DSA:3.40.50.10320 1 222 8.8E-38 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS29495 a03531b6de03ba825cd31f8df7c0bd88 222 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 123 3.9E-20 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A616_RS29495 a03531b6de03ba825cd31f8df7c0bd88 222 SUPERFAMILY SSF102588 1 219 1.31E-41 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS19450 f24e7bb3ec3b694bd9d26a918d99ac38 381 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 205 210 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A616_RS19450 f24e7bb3ec3b694bd9d26a918d99ac38 381 Gene3D G3DSA:2.40.10.10 174 266 1.5E-11 T 29-03-2018 A616_RS19450 f24e7bb3ec3b694bd9d26a918d99ac38 381 SUPERFAMILY SSF50494 169 366 1.96E-14 T 29-03-2018 IPR009003 Peptidase S1, PA clan A616_RS10635 9c18e625de0a5022d1ebc27ea5ae7ddb 190 Pfam PF08955 BofC C-terminal domain 107 183 3.0E-27 T 29-03-2018 IPR015050 Bypass of forespore C, C-terminal A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 Gene3D G3DSA:1.10.10.10 126 233 1.4E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 SMART SM00862 150 226 5.0E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 SUPERFAMILY SSF52172 1 127 3.27E-38 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 SMART SM00448 1 113 4.0E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 6.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 Pfam PF00072 Response regulator receiver domain 3 114 3.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 SUPERFAMILY SSF46894 128 227 3.97E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A616_RS02405 aea37edc1cbf3d394d547e2153458685 235 Gene3D G3DSA:3.40.50.2300 1 125 1.2E-34 T 29-03-2018 A616_RS28100 ac37ada36303c815d191a936f9dc8cc7 445 Pfam PF17482 Phage tail sheath C-terminal domain 349 439 2.1E-9 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain A616_RS28100 ac37ada36303c815d191a936f9dc8cc7 445 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 187 340 6.4E-11 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain A616_RS28030 64831a7a334106884fbb532e815f4137 204 Pfam PF14301 Domain of unknown function (DUF4376) 112 200 7.9E-12 T 29-03-2018 IPR025484 Domain of unknown function DUF4376 A616_RS27130 7a86a0ac26ee43dc95d5ed112abeef90 74 Gene3D G3DSA:3.30.1450.10 1 74 4.3E-17 T 29-03-2018 A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 Gene3D G3DSA:2.30.30.40 45 112 2.2E-37 T 29-03-2018 A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 Gene3D G3DSA:2.20.25.10 2 40 7.7E-17 T 29-03-2018 A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 Pfam PF03831 PhnA domain 46 113 9.9E-34 T 29-03-2018 IPR013988 PhnA protein, C-terminal A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 SUPERFAMILY SSF82057 41 113 8.7E-30 T 29-03-2018 A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 SUPERFAMILY SSF57783 3 36 6.8E-14 T 29-03-2018 A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 Pfam PF08274 PhnA Zinc-Ribbon 3 32 6.2E-15 T 29-03-2018 IPR013987 PhnA protein, N-terminal A616_RS31675 0ddc08b222a813af93452e563d79dc6b 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 1.1E-49 T 29-03-2018 IPR004624 PhnA protein A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 SUPERFAMILY SSF55920 2 246 7.59E-69 T 29-03-2018 IPR000994 Peptidase M24 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 Pfam PF00557 Metallopeptidase family M24 12 239 1.1E-45 T 29-03-2018 IPR000994 Peptidase M24 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 Gene3D G3DSA:3.90.230.10 1 247 4.3E-67 T 29-03-2018 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 Hamap MF_01974 Methionine aminopeptidase [map]. 1 247 33.616 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 1.1E-18 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.1E-18 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 PRINTS PR00599 Methionine aminopeptidase-1 signature 158 170 1.1E-18 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 PRINTS PR00599 Methionine aminopeptidase-1 signature 88 104 1.1E-18 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS28145 220d082cd2c16f3ef0407dc433600b96 247 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 247 1.5E-86 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A616_RS01815 74dd02f6ec8b65c97102eda655a79efe 356 Pfam PF00296 Luciferase-like monooxygenase 15 302 1.4E-48 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS01815 74dd02f6ec8b65c97102eda655a79efe 356 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 2 339 1.4E-157 T 29-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative A616_RS01815 74dd02f6ec8b65c97102eda655a79efe 356 Gene3D G3DSA:3.20.20.30 1 355 1.6E-79 T 29-03-2018 A616_RS01815 74dd02f6ec8b65c97102eda655a79efe 356 SUPERFAMILY SSF51679 3 340 6.36E-79 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS11410 9757641f83ae52b0af191185af109ecd 239 SUPERFAMILY SSF51261 10 138 6.28E-37 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS11410 9757641f83ae52b0af191185af109ecd 239 Gene3D G3DSA:2.70.70.10 4 141 7.0E-32 T 29-03-2018 A616_RS11410 9757641f83ae52b0af191185af109ecd 239 Pfam PF01551 Peptidase family M23 32 127 5.5E-23 T 29-03-2018 IPR016047 Peptidase M23 A616_RS29670 4961b52e4e2752bb9e5419eb5636e338 413 Pfam PF13439 Glycosyltransferase Family 4 28 196 6.2E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS29670 4961b52e4e2752bb9e5419eb5636e338 413 Gene3D G3DSA:3.40.50.2000 201 382 1.9E-21 T 29-03-2018 A616_RS29670 4961b52e4e2752bb9e5419eb5636e338 413 Gene3D G3DSA:3.40.50.2000 19 200 1.8E-5 T 29-03-2018 A616_RS29670 4961b52e4e2752bb9e5419eb5636e338 413 Pfam PF13692 Glycosyl transferases group 1 225 366 1.3E-11 T 29-03-2018 A616_RS29670 4961b52e4e2752bb9e5419eb5636e338 413 SUPERFAMILY SSF53756 30 406 5.18E-37 T 29-03-2018 A616_RS17675 c8191a138d4c22d138505bd433367df3 240 SUPERFAMILY SSF141868 5 236 5.89E-44 T 29-03-2018 IPR001633 EAL domain A616_RS17675 c8191a138d4c22d138505bd433367df3 240 Gene3D G3DSA:3.20.20.450 1 239 8.7E-46 T 29-03-2018 IPR001633 EAL domain A616_RS17675 c8191a138d4c22d138505bd433367df3 240 Pfam PF00563 EAL domain 12 230 3.1E-39 T 29-03-2018 IPR001633 EAL domain A616_RS17675 c8191a138d4c22d138505bd433367df3 240 SMART SM00052 1 235 8.4E-12 T 29-03-2018 IPR001633 EAL domain A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 392 42.936 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PIRSF PIRSF000724 1 394 1.1E-160 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 345 356 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 368 385 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 1.6E-96 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 Gene3D G3DSA:3.40.50.1260 3 178 3.3E-75 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 SUPERFAMILY SSF53748 1 392 7.42E-163 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 Pfam PF00162 Phosphoglycerate kinase 6 382 2.5E-167 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29040 26b63f16cfcb6722308e247762f809d2 394 Gene3D G3DSA:3.40.50.1260 179 380 6.8E-88 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A616_RS29805 153e5ef85d78df5768d8007bc78c3e5b 94 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 80 7.0E-45 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID A616_RS29805 153e5ef85d78df5768d8007bc78c3e5b 94 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A616_RS29805 153e5ef85d78df5768d8007bc78c3e5b 94 Gene3D G3DSA:1.10.10.10 2 32 3.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29805 153e5ef85d78df5768d8007bc78c3e5b 94 Gene3D G3DSA:1.10.260.40 33 84 2.0E-5 T 29-03-2018 A616_RS29805 153e5ef85d78df5768d8007bc78c3e5b 94 Pfam PF12116 Stage III sporulation protein D 2 81 4.6E-41 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID A616_RS06290 dd190ddb20f384b8f7f6224ff5b16a19 143 SUPERFAMILY SSF54211 21 135 1.06E-5 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS23225 7594642e99934aae444e8a424a2e3a22 371 Gene3D G3DSA:2.30.300.10 24 196 8.6E-16 T 29-03-2018 A616_RS23225 7594642e99934aae444e8a424a2e3a22 371 SUPERFAMILY SSF69279 26 204 1.36E-27 T 29-03-2018 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 SUPERFAMILY SSF103473 7 392 1.31E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 Gene3D G3DSA:1.20.1250.20 2 199 9.8E-43 T 29-03-2018 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 Pfam PF07690 Major Facilitator Superfamily 214 400 1.1E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 Pfam PF07690 Major Facilitator Superfamily 18 199 7.8E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 Gene3D G3DSA:1.20.1250.20 200 405 9.8E-26 T 29-03-2018 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 PRINTS PR01035 Tetracycline resistance protein signature 168 188 1.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 PRINTS PR01035 Tetracycline resistance protein signature 24 40 1.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS11195 9f98ebd0539375e9f29fa0a9b89bb532 405 PRINTS PR01035 Tetracycline resistance protein signature 81 105 1.1E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS09190 7524b0b03a960685eb62057ebc0a0232 411 Gene3D G3DSA:2.30.40.10 1 77 9.7E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09190 7524b0b03a960685eb62057ebc0a0232 411 SUPERFAMILY SSF51556 68 372 8.98E-72 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS09190 7524b0b03a960685eb62057ebc0a0232 411 Gene3D G3DSA:3.20.20.140 78 355 3.7E-31 T 29-03-2018 A616_RS09190 7524b0b03a960685eb62057ebc0a0232 411 SUPERFAMILY SSF51338 29 85 2.71E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS09190 7524b0b03a960685eb62057ebc0a0232 411 Pfam PF07969 Amidohydrolase family 175 406 1.7E-14 T 29-03-2018 IPR013108 Amidohydrolase 3 A616_RS27070 2eee066b9058d3053749487dc8466aef 180 SUPERFAMILY SSF88659 98 166 4.11E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS27070 2eee066b9058d3053749487dc8466aef 180 Gene3D G3DSA:1.10.10.10 75 168 5.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27070 2eee066b9058d3053749487dc8466aef 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 164 1.2E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS27070 2eee066b9058d3053749487dc8466aef 180 Pfam PF04542 Sigma-70 region 2 13 78 1.2E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS27070 2eee066b9058d3053749487dc8466aef 180 Pfam PF08281 Sigma-70, region 4 110 159 5.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS27070 2eee066b9058d3053749487dc8466aef 180 Gene3D G3DSA:1.10.1740.10 1 74 5.5E-21 T 29-03-2018 A616_RS27070 2eee066b9058d3053749487dc8466aef 180 SUPERFAMILY SSF88946 6 90 3.14E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS20700 7f86e56ad90ea7b76456d1a36c37bc82 121 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 1.1E-33 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 A616_RS23660 6807badfc8c9e008e8f7b6d69f4e1d49 320 Pfam PF00005 ABC transporter 22 163 5.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS23660 6807badfc8c9e008e8f7b6d69f4e1d49 320 Gene3D G3DSA:3.40.50.300 2 294 1.1E-52 T 29-03-2018 A616_RS23660 6807badfc8c9e008e8f7b6d69f4e1d49 320 SUPERFAMILY SSF52540 4 222 6.68E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23660 6807badfc8c9e008e8f7b6d69f4e1d49 320 SMART SM00382 30 211 1.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS23660 6807badfc8c9e008e8f7b6d69f4e1d49 320 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS29960 39ca95a170dd430931041d73d7864935 245 Pfam PF12697 Alpha/beta hydrolase family 34 219 1.7E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS29960 39ca95a170dd430931041d73d7864935 245 SUPERFAMILY SSF53474 4 233 6.41E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS29960 39ca95a170dd430931041d73d7864935 245 Gene3D G3DSA:3.40.50.1820 2 236 1.2E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS18935 87287c3d7874fdb9643d914fe610e66b 102 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 98 1.8E-6 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS18935 87287c3d7874fdb9643d914fe610e66b 102 SUPERFAMILY SSF89360 1 87 8.76E-7 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS18935 87287c3d7874fdb9643d914fe610e66b 102 Gene3D G3DSA:2.60.300.12 1 99 5.1E-14 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS12305 39d2ec5f4e52f82211a494f2218b0dc4 518 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 146 171 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A616_RS12305 39d2ec5f4e52f82211a494f2218b0dc4 518 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 31 432 2.2E-70 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS12305 39d2ec5f4e52f82211a494f2218b0dc4 518 Pfam PF00474 Sodium:solute symporter family 31 432 1.6E-108 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS31980 771bbb4dca4abae4684016ceb559ddcb 148 Pfam PF14300 Domain of unknown function (DUF4375) 28 139 4.9E-21 T 29-03-2018 IPR025402 Domain of unknown function DUF4375 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 308 3.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 Gene3D G3DSA:1.10.287.130 233 306 3.3E-14 T 29-03-2018 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 SMART SM00387 355 467 3.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 SUPERFAMILY SSF55874 300 465 4.85E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 1.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 1.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 1.9E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 SMART SM00304 189 242 8.4E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 SUPERFAMILY SSF47384 226 308 4.12E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 Gene3D G3DSA:3.30.565.10 310 467 1.2E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 466 3.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 SUPERFAMILY SSF158472 189 239 5.62E-8 T 29-03-2018 A616_RS05440 4bdfba84a1dee0c56139002d36b337f2 467 SMART SM00388 243 310 3.4E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A616_RS07850 e2b96885ae6ea1d1367b6c4d47539e13 559 SUPERFAMILY SSF51445 44 210 9.95E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS07850 e2b96885ae6ea1d1367b6c4d47539e13 559 Gene3D G3DSA:3.20.20.80 32 304 4.2E-6 T 29-03-2018 A616_RS07850 e2b96885ae6ea1d1367b6c4d47539e13 559 Gene3D G3DSA:3.20.20.80 305 557 3.7E-4 T 29-03-2018 A616_RS07520 6f005121d0f23739c281ccea1bf65926 143 Pfam PF07485 Domain of Unknown Function (DUF1259) 20 139 4.8E-33 T 29-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A616_RS12300 cbdd1f512b6205b521a8d1016f61f16a 508 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A616_RS12300 cbdd1f512b6205b521a8d1016f61f16a 508 Pfam PF00474 Sodium:solute symporter family 33 431 3.8E-125 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS12300 cbdd1f512b6205b521a8d1016f61f16a 508 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 431 4.1E-91 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 Pfam PF00549 CoA-ligase 262 381 3.5E-26 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 Gene3D G3DSA:3.30.470.20 96 239 2.5E-57 T 29-03-2018 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 Gene3D G3DSA:3.30.1490.20 21 95 1.1E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 PIRSF PIRSF001554 1 386 3.3E-154 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 SUPERFAMILY SSF52210 239 386 5.89E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 Gene3D G3DSA:3.40.50.261 240 385 9.9E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 45.118 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 SUPERFAMILY SSF56059 1 238 3.18E-88 T 29-03-2018 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.3E-166 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A616_RS20100 d62b176d78a119808c69b1c4fde3146e 386 Pfam PF08442 ATP-grasp domain 2 203 1.1E-82 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A616_RS19530 08e5e17ab2db8527eedbc1b74d7f2c3e 186 Pfam PF10628 Outer spore coat protein E (CotE) 9 181 4.9E-61 T 29-03-2018 IPR018901 Spore coat protein CotE A616_RS02670 21c6720110135ad625fa6dbe2c526c79 328 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 80 230 1.6E-47 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS02670 21c6720110135ad625fa6dbe2c526c79 328 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 229 1.4E-44 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 516 45.438 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 Gene3D G3DSA:3.40.50.1380 1 193 4.7E-75 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 Gene3D G3DSA:3.40.140.20 366 506 4.0E-50 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 SMART SM00798 135 451 2.0E-197 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 Gene3D G3DSA:3.40.140.20 224 360 3.5E-54 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 Pfam PF02142 MGS-like domain 15 130 2.7E-27 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 SUPERFAMILY SSF52335 3 195 8.5E-71 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 SMART SM00851 15 130 3.9E-55 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 SUPERFAMILY SSF53927 207 516 5.92E-126 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 516 3.6E-224 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 PIRSF PIRSF000414 1 516 5.4E-215 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS03595 14e1986e7f8aaace914a88ab580a446c 516 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 450 1.1E-121 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A616_RS21710 97d2b0b938442c7c0ac2c1c262f4f7a9 302 SUPERFAMILY SSF103481 42 137 8.24E-7 T 29-03-2018 A616_RS21710 97d2b0b938442c7c0ac2c1c262f4f7a9 302 Pfam PF00892 EamA-like transporter family 150 281 6.5E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS21710 97d2b0b938442c7c0ac2c1c262f4f7a9 302 Pfam PF00892 EamA-like transporter family 6 136 2.7E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS21710 97d2b0b938442c7c0ac2c1c262f4f7a9 302 SUPERFAMILY SSF103481 198 284 1.02E-8 T 29-03-2018 A616_RS14190 c95ee3ef6c91c561317f95e21f371ca3 178 Pfam PF00692 dUTPase 135 175 3.3E-6 T 29-03-2018 IPR029054 dUTPase-like A616_RS14190 c95ee3ef6c91c561317f95e21f371ca3 178 Pfam PF00692 dUTPase 21 103 2.0E-12 T 29-03-2018 IPR029054 dUTPase-like A616_RS14190 c95ee3ef6c91c561317f95e21f371ca3 178 Gene3D G3DSA:2.70.40.10 1 178 4.2E-56 T 29-03-2018 A616_RS14190 c95ee3ef6c91c561317f95e21f371ca3 178 SUPERFAMILY SSF51283 11 176 3.66E-41 T 29-03-2018 IPR029054 dUTPase-like A616_RS16725 78bb74e10a47afdd53750e12a56eaff5 576 Gene3D G3DSA:3.90.1600.10 296 431 7.2E-22 T 29-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS16725 78bb74e10a47afdd53750e12a56eaff5 576 SUPERFAMILY SSF56672 228 562 1.06E-46 T 29-03-2018 A616_RS16725 78bb74e10a47afdd53750e12a56eaff5 576 Gene3D G3DSA:3.90.1600.10 249 295 3.9E-6 T 29-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A616_RS16725 78bb74e10a47afdd53750e12a56eaff5 576 Gene3D G3DSA:3.30.420.10 23 197 9.0E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS07795 cf7051b9ad816d9318b60e056f112f08 184 PIRSF PIRSF000239 4 184 3.7E-61 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS07795 cf7051b9ad816d9318b60e056f112f08 184 SUPERFAMILY SSF52833 9 183 2.7E-62 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS07795 cf7051b9ad816d9318b60e056f112f08 184 Pfam PF00578 AhpC/TSA family 11 145 9.9E-42 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS07795 cf7051b9ad816d9318b60e056f112f08 184 Gene3D G3DSA:3.40.30.10 1 161 3.3E-42 T 29-03-2018 A616_RS07795 cf7051b9ad816d9318b60e056f112f08 184 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 170 184 2.2E-4 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS07795 cf7051b9ad816d9318b60e056f112f08 184 Gene3D G3DSA:3.30.1020.10 162 184 3.9E-5 T 29-03-2018 A616_RS14435 8492e9e822e836e54f47382ec948930e 82 ProDom PD058323 YUZF BH2251 15 81 2.0E-16 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 A616_RS14435 8492e9e822e836e54f47382ec948930e 82 Pfam PF10842 Protein of unknown function (DUF2642) 19 81 2.6E-31 T 29-03-2018 IPR020139 Protein of unknown function DUF2642 A616_RS30730 b9e83c1da85d083c948aeb4bbaaadaf4 147 Gene3D G3DSA:3.40.50.300 3 147 1.8E-16 T 29-03-2018 A616_RS30730 b9e83c1da85d083c948aeb4bbaaadaf4 147 SUPERFAMILY SSF52540 3 146 3.14E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30730 b9e83c1da85d083c948aeb4bbaaadaf4 147 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 4 142 6.8E-43 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 A616_RS30730 b9e83c1da85d083c948aeb4bbaaadaf4 147 PIRSF PIRSF036409 2 147 1.0E-44 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 A616_RS30730 b9e83c1da85d083c948aeb4bbaaadaf4 147 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 4 142 7.4E-42 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 Gene3D G3DSA:3.40.640.10 6 284 2.0E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 Gene3D G3DSA:3.90.100.10 372 490 2.0E-34 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 SUPERFAMILY SSF53383 6 382 2.79E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 370 2.8E-106 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 SUPERFAMILY SSF55904 341 484 7.72E-39 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS21580 fbb893397a9f5de28c1d9b5ac64dff65 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 373 458 6.5E-11 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 A616_RS18095 67a96b5eb74aaa252fe59d29e22993c2 160 Pfam PF00583 Acetyltransferase (GNAT) family 55 138 2.8E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS18095 67a96b5eb74aaa252fe59d29e22993c2 160 SUPERFAMILY SSF55729 20 159 2.06E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS18095 67a96b5eb74aaa252fe59d29e22993c2 160 Gene3D G3DSA:3.40.630.30 9 160 4.3E-22 T 29-03-2018 A616_RS27350 cbce3343c5d6e9cebe94505e7888b073 172 SUPERFAMILY SSF159234 1 163 9.42E-35 T 29-03-2018 IPR007295 Domain of unknown function DUF402 A616_RS27350 cbce3343c5d6e9cebe94505e7888b073 172 Pfam PF04167 Protein of unknown function (DUF402) 61 129 7.0E-21 T 29-03-2018 IPR007295 Domain of unknown function DUF402 A616_RS27350 cbce3343c5d6e9cebe94505e7888b073 172 Gene3D G3DSA:2.40.380.10 32 167 1.5E-26 T 29-03-2018 IPR007295 Domain of unknown function DUF402 A616_RS18575 b09ac9644a6ba5935a6cdcdc45cdea1a 56 Pfam PF14174 YycC-like protein 1 50 5.8E-29 T 29-03-2018 IPR025550 YycC-like protein A616_RS18575 b09ac9644a6ba5935a6cdcdc45cdea1a 56 Gene3D G3DSA:1.10.260.40 4 56 2.3E-4 T 29-03-2018 A616_RS08385 b9136e43c30a3b9541e1cfe64362e5bd 137 Pfam PF01797 Transposase IS200 like 15 132 3.0E-37 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A616_RS08385 b9136e43c30a3b9541e1cfe64362e5bd 137 Gene3D G3DSA:3.30.70.1290 3 131 3.3E-24 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A616_RS08385 b9136e43c30a3b9541e1cfe64362e5bd 137 SMART SM01321 15 132 9.6E-41 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A616_RS08385 b9136e43c30a3b9541e1cfe64362e5bd 137 SUPERFAMILY SSF143422 9 134 1.96E-42 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 Gene3D G3DSA:1.10.10.10 133 209 8.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 SUPERFAMILY SSF51206 11 126 6.15E-23 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 SMART SM00100 1 116 2.8E-4 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 SUPERFAMILY SSF46785 134 204 1.23E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 Pfam PF13545 Crp-like helix-turn-helix domain 137 202 7.7E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 Gene3D G3DSA:2.60.120.10 15 126 2.9E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS16190 2a8d4e43f2aad9227b05f741e5830e73 210 Pfam PF00027 Cyclic nucleotide-binding domain 21 104 3.2E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain A616_RS16030 ef6af6468f8ff52e77facf8f0cfb4792 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 72 6.5E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS16030 ef6af6468f8ff52e77facf8f0cfb4792 297 Gene3D G3DSA:1.10.3720.10 24 284 1.5E-43 T 29-03-2018 A616_RS16030 ef6af6468f8ff52e77facf8f0cfb4792 297 SUPERFAMILY SSF161098 90 282 2.09E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS16030 ef6af6468f8ff52e77facf8f0cfb4792 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 296 2.4E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12510 5e44615fbb2686f310ffbb8ebf8ca20a 267 Gene3D G3DSA:3.40.50.1820 3 267 1.1E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS12510 5e44615fbb2686f310ffbb8ebf8ca20a 267 Pfam PF00756 Putative esterase 23 193 2.8E-19 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A616_RS12510 5e44615fbb2686f310ffbb8ebf8ca20a 267 SUPERFAMILY SSF53474 4 265 2.49E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24800 a1e141c29eeb29156622a69b9b7a1014 214 Gene3D G3DSA:3.40.50.850 2 207 2.5E-36 T 29-03-2018 A616_RS24800 a1e141c29eeb29156622a69b9b7a1014 214 Pfam PF00857 Isochorismatase family 14 166 1.8E-25 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS24800 a1e141c29eeb29156622a69b9b7a1014 214 SUPERFAMILY SSF52499 7 206 8.9E-50 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS22395 42f93a92a59ed4642a8754bf3dcf44ca 411 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A616_RS22395 42f93a92a59ed4642a8754bf3dcf44ca 411 Gene3D G3DSA:1.20.1250.20 4 184 5.4E-29 T 29-03-2018 A616_RS22395 42f93a92a59ed4642a8754bf3dcf44ca 411 Pfam PF07690 Major Facilitator Superfamily 19 279 1.8E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS22395 42f93a92a59ed4642a8754bf3dcf44ca 411 SUPERFAMILY SSF103473 12 393 1.31E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS22395 42f93a92a59ed4642a8754bf3dcf44ca 411 Gene3D G3DSA:1.20.1250.20 208 409 7.0E-23 T 29-03-2018 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 Gene3D G3DSA:3.50.50.60 140 302 1.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 SUPERFAMILY SSF51905 2 299 1.44E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 288 2.8E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 2.5E-10 T 29-03-2018 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.5E-10 T 29-03-2018 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.5E-10 T 29-03-2018 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.5E-10 T 29-03-2018 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 Gene3D G3DSA:3.50.50.60 1 131 3.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 6.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 6.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 6.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 6.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS13580 b3610488e5601964f8eadf0f355b58da 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 37 52 6.5E-12 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 Pfam PF07501 G5 domain 156 228 8.6E-19 T 29-03-2018 IPR011098 G5 domain A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 Gene3D G3DSA:2.40.40.10 150 363 3.9E-40 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 Pfam PF03990 Domain of unknown function (DUF348) 101 138 1.1E-11 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 Pfam PF03990 Domain of unknown function (DUF348) 42 81 1.5E-8 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 SUPERFAMILY SSF50685 290 355 4.88E-12 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 SMART SM01208 152 230 2.1E-23 T 29-03-2018 IPR011098 G5 domain A616_RS00630 a57bde625bc23bc4b62b8444f3e296a9 365 Pfam PF06725 3D domain 300 360 2.7E-15 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A616_RS12950 71bdcf48d0db16581eeb197818972dfe 283 Pfam PF01063 Amino-transferase class IV 28 251 4.0E-50 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS12950 71bdcf48d0db16581eeb197818972dfe 283 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 3 277 3.5E-110 T 29-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 A616_RS12950 71bdcf48d0db16581eeb197818972dfe 283 Gene3D G3DSA:3.20.10.10 132 281 1.1E-43 T 29-03-2018 A616_RS12950 71bdcf48d0db16581eeb197818972dfe 283 Gene3D G3DSA:3.30.470.10 1 131 2.4E-28 T 29-03-2018 A616_RS12950 71bdcf48d0db16581eeb197818972dfe 283 SUPERFAMILY SSF56752 2 277 7.19E-81 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS12950 71bdcf48d0db16581eeb197818972dfe 283 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A616_RS24785 dbcede55f49bd6c37e7466cdf428b3d2 64 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 55 3.9E-19 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A616_RS24785 dbcede55f49bd6c37e7466cdf428b3d2 64 SMART SM00704 21 60 9.9E-4 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 A616_RS26925 0c9b1f7a479bc8c0e881787d9fa5d637 371 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 198 368 3.2E-33 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS26925 0c9b1f7a479bc8c0e881787d9fa5d637 371 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 3 371 1.7E-64 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS27595 439fbe5fe33a7bed18f68036fc82d3aa 214 Pfam PF13624 SurA N-terminal domain 56 130 5.9E-11 T 29-03-2018 A616_RS27595 439fbe5fe33a7bed18f68036fc82d3aa 214 SUPERFAMILY SSF109998 32 150 6.87E-24 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS27595 439fbe5fe33a7bed18f68036fc82d3aa 214 Gene3D G3DSA:1.10.4030.10 27 130 1.2E-15 T 29-03-2018 A616_RS27595 439fbe5fe33a7bed18f68036fc82d3aa 214 Gene3D G3DSA:1.10.4030.10 131 183 0.099 T 29-03-2018 A616_RS24330 1704895855ec12ede1c9fae6b7e76740 428 SUPERFAMILY SSF81296 29 126 3.85E-16 T 29-03-2018 IPR014756 Immunoglobulin E-set A616_RS24330 1704895855ec12ede1c9fae6b7e76740 428 Gene3D G3DSA:2.60.40.1220 29 127 8.0E-21 T 29-03-2018 A616_RS24330 1704895855ec12ede1c9fae6b7e76740 428 Pfam PF04234 CopC domain 30 126 6.8E-17 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 A616_RS26520 909fc43d50c4aae5ab538c598af3a2b6 362 Pfam PF03845 Spore germination protein 9 317 6.7E-53 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26520 909fc43d50c4aae5ab538c598af3a2b6 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 16 351 6.0E-46 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26940 8b005aafbd916370ffccaee7be4bab54 362 Pfam PF03845 Spore germination protein 6 292 5.9E-28 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26940 8b005aafbd916370ffccaee7be4bab54 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 352 5.9E-62 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS25230 ec4ed405e623e004cde14b9e5a3fcf3f 555 Gene3D G3DSA:3.40.190.10 226 322 4.4E-27 T 29-03-2018 A616_RS25230 ec4ed405e623e004cde14b9e5a3fcf3f 555 SUPERFAMILY SSF53850 53 550 2.17E-138 T 29-03-2018 A616_RS25230 ec4ed405e623e004cde14b9e5a3fcf3f 555 Gene3D G3DSA:3.10.105.10 323 529 5.0E-56 T 29-03-2018 A616_RS25230 ec4ed405e623e004cde14b9e5a3fcf3f 555 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 101 477 8.9E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS25230 ec4ed405e623e004cde14b9e5a3fcf3f 555 Gene3D G3DSA:3.90.76.10 68 225 3.5E-39 T 29-03-2018 A616_RS25230 ec4ed405e623e004cde14b9e5a3fcf3f 555 PIRSF PIRSF002741 2 553 2.4E-137 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 Gene3D G3DSA:3.30.830.10 237 411 1.5E-48 T 29-03-2018 A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 5.5E-45 T 29-03-2018 IPR011765 Peptidase M16, N-terminal A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 Pfam PF05193 Peptidase M16 inactive domain 165 338 6.0E-34 T 29-03-2018 IPR007863 Peptidase M16, C-terminal A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 SUPERFAMILY SSF63411 222 405 6.06E-49 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 Gene3D G3DSA:3.30.830.10 2 218 4.2E-58 T 29-03-2018 A616_RS19755 35350e45c608defd8ae16cada6d019ab 417 SUPERFAMILY SSF63411 2 204 9.17E-58 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A616_RS00265 7a1c695c70923125591227fae5414ea9 262 Gene3D G3DSA:1.10.3720.10 5 262 2.9E-36 T 29-03-2018 A616_RS00265 7a1c695c70923125591227fae5414ea9 262 SUPERFAMILY SSF161098 9 258 2.9E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS00265 7a1c695c70923125591227fae5414ea9 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 252 2.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS18200 cae948dbe3bbf2009a76b0cc8dde74ff 273 Gene3D G3DSA:3.40.50.1820 14 269 1.6E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS18200 cae948dbe3bbf2009a76b0cc8dde74ff 273 Pfam PF00756 Putative esterase 23 182 2.6E-20 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A616_RS18200 cae948dbe3bbf2009a76b0cc8dde74ff 273 SUPERFAMILY SSF53474 9 267 2.63E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS08275 396ad9e3b5a204adfe004d09eae445e2 148 Gene3D G3DSA:3.30.530.20 12 143 8.2E-16 T 29-03-2018 IPR023393 START-like domain A616_RS08275 396ad9e3b5a204adfe004d09eae445e2 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 31 140 2.0E-11 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS08275 396ad9e3b5a204adfe004d09eae445e2 148 SUPERFAMILY SSF55961 15 140 5.5E-18 T 29-03-2018 A616_RS24520 b430e125a39da9d5f4e5da53f7b0980d 909 Pfam PF15604 Novel toxin 15 761 907 2.2E-43 T 29-03-2018 IPR028949 Novel toxin 15 A616_RS24520 b430e125a39da9d5f4e5da53f7b0980d 909 Gene3D G3DSA:1.20.120.20 534 692 9.5E-9 T 29-03-2018 A616_RS24520 b430e125a39da9d5f4e5da53f7b0980d 909 SUPERFAMILY SSF69279 16 178 1.83E-26 T 29-03-2018 A616_RS24520 b430e125a39da9d5f4e5da53f7b0980d 909 Gene3D G3DSA:3.55.50.10 103 202 3.8E-12 T 29-03-2018 A616_RS24520 b430e125a39da9d5f4e5da53f7b0980d 909 Pfam PF05954 Phage late control gene D protein (GPD) 72 183 1.4E-9 T 29-03-2018 A616_RS24520 b430e125a39da9d5f4e5da53f7b0980d 909 Gene3D G3DSA:2.40.50.230 295 361 0.0021 T 29-03-2018 IPR006531 Gp5 N-terminal A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 Gene3D G3DSA:3.20.20.70 1 214 1.6E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 204 1.3E-55 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 SUPERFAMILY SSF51569 1 212 4.81E-77 T 29-03-2018 A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 6.1E-98 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A616_RS30095 e1b29be09c220012c9ee7096ab9838d9 214 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.264 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 A616_RS06745 6e125642ede0477767a96352037f10dc 174 Pfam PF06114 IrrE N-terminal-like domain 58 158 8.6E-14 T 29-03-2018 IPR010359 IrrE N-terminal-like domain A616_RS06370 7ccf2b6327ad43612c1dd458c6224d88 126 Gene3D G3DSA:1.10.3230.10 1 125 1.8E-18 T 29-03-2018 A616_RS06370 7ccf2b6327ad43612c1dd458c6224d88 126 Pfam PF11436 Protein of unknown function (DUF3199) 1 115 2.1E-7 T 29-03-2018 IPR013514 Protein of unknown function DUF3199, YqbG A616_RS06370 7ccf2b6327ad43612c1dd458c6224d88 126 SUPERFAMILY SSF116915 2 115 7.19E-10 T 29-03-2018 IPR013514 Protein of unknown function DUF3199, YqbG A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 Pfam PF00005 ABC transporter 398 546 1.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 SUPERFAMILY SSF90123 34 366 1.09E-90 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 SMART SM00382 406 592 8.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 SUPERFAMILY SSF52540 371 617 3.52E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 Pfam PF00664 ABC transporter transmembrane region 51 334 1.1E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 Gene3D G3DSA:3.40.50.300 368 622 1.1E-75 T 29-03-2018 A616_RS15730 e5abbaa993538999406ff103cfdb8938 624 Gene3D G3DSA:1.20.1560.10 23 367 9.8E-104 T 29-03-2018 A616_RS10845 2a8cb633b61a78af18deb6e9a70a8d09 138 Gene3D G3DSA:3.30.420.140 1 138 4.1E-51 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A616_RS10845 2a8cb633b61a78af18deb6e9a70a8d09 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 5 134 1.5E-51 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A616_RS10845 2a8cb633b61a78af18deb6e9a70a8d09 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 2 137 27.583 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A616_RS10845 2a8cb633b61a78af18deb6e9a70a8d09 138 SUPERFAMILY SSF53098 2 136 2.12E-47 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS10845 2a8cb633b61a78af18deb6e9a70a8d09 138 SMART SM00732 2 102 1.5E-42 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A616_RS10845 2a8cb633b61a78af18deb6e9a70a8d09 138 Pfam PF03652 Holliday junction resolvase 3 134 6.8E-49 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A616_RS00535 feae1c3ff1ee625c4795366182ca39d9 76 Pfam PF10704 Protein of unknown function (DUF2508) 6 70 4.6E-10 T 29-03-2018 IPR019644 Protein of unknown function DUF2508 A616_RS08175 13355702a784f572882a0f63cbb208d3 101 SUPERFAMILY SSF54909 1 99 2.41E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS08175 13355702a784f572882a0f63cbb208d3 101 Gene3D G3DSA:3.30.70.100 3 100 8.0E-20 T 29-03-2018 A616_RS08175 13355702a784f572882a0f63cbb208d3 101 Pfam PF07978 NIPSNAP 6 99 1.3E-23 T 29-03-2018 IPR012577 NIPSNAP A616_RS17985 61fec0c50e674be800b741c1ce2547d2 260 Gene3D G3DSA:3.40.50.300 2 255 4.0E-60 T 29-03-2018 A616_RS17985 61fec0c50e674be800b741c1ce2547d2 260 SUPERFAMILY SSF52540 5 233 2.28E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS17985 61fec0c50e674be800b741c1ce2547d2 260 SMART SM00382 29 209 5.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS17985 61fec0c50e674be800b741c1ce2547d2 260 Pfam PF00005 ABC transporter 20 159 1.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS17985 61fec0c50e674be800b741c1ce2547d2 260 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS26225 957ecbcc3f698a017607cbac2b25d40c 143 SUPERFAMILY SSF51735 10 139 7.88E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS26225 957ecbcc3f698a017607cbac2b25d40c 143 SMART SM00881 14 110 2.1E-16 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS26225 957ecbcc3f698a017607cbac2b25d40c 143 Gene3D G3DSA:3.40.50.720 14 140 1.5E-30 T 29-03-2018 A616_RS26225 957ecbcc3f698a017607cbac2b25d40c 143 Pfam PF13380 CoA binding domain 18 136 3.6E-35 T 29-03-2018 IPR003781 CoA-binding GO:0048037 A616_RS17980 4a47dbf83281b845cb1decdaeffea335 252 SUPERFAMILY SSF161098 51 235 1.83E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS17980 4a47dbf83281b845cb1decdaeffea335 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 246 1.0E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS17980 4a47dbf83281b845cb1decdaeffea335 252 Gene3D G3DSA:1.10.3720.10 45 244 4.1E-26 T 29-03-2018 A616_RS20070 380cafa84b4dcb92d885f2b738226a5d 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 179 1.2E-81 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A616_RS20070 380cafa84b4dcb92d885f2b738226a5d 180 SUPERFAMILY SSF56235 3 178 9.16E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS20070 380cafa84b4dcb92d885f2b738226a5d 180 Pfam PF00227 Proteasome subunit 5 176 2.9E-24 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A616_RS20070 380cafa84b4dcb92d885f2b738226a5d 180 PIRSF PIRSF039093 1 180 2.4E-83 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A616_RS20070 380cafa84b4dcb92d885f2b738226a5d 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 179 40.624 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A616_RS20070 380cafa84b4dcb92d885f2b738226a5d 180 Gene3D G3DSA:3.60.20.10 7 179 4.7E-26 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A616_RS26835 70e239bdc96ab489f9575b8412c53034 270 Pfam PF10977 Protein of unknown function (DUF2797) 39 262 8.6E-83 T 29-03-2018 IPR021246 Protein of unknown function DUF2797 A616_RS06355 7fd78c2d6a0ef32278c2a8064567e565 410 Gene3D G3DSA:1.20.120.490 241 341 0.0012 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain A616_RS06355 7fd78c2d6a0ef32278c2a8064567e565 410 Pfam PF14550 Putative phage serine protease XkdF 41 157 8.6E-40 T 29-03-2018 IPR027924 Phage-like element PBSX protein, XkdF A616_RS09830 35315da56653724100771655e7399775 287 Gene3D G3DSA:1.10.3720.10 62 283 1.9E-16 T 29-03-2018 A616_RS09830 35315da56653724100771655e7399775 287 SUPERFAMILY SSF161098 69 270 1.27E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09830 35315da56653724100771655e7399775 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 284 9.0E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS08320 a9a7bb507e62bffa4eb75e58d0cadf53 145 Gene3D G3DSA:3.30.530.20 6 145 1.8E-12 T 29-03-2018 IPR023393 START-like domain A616_RS08320 a9a7bb507e62bffa4eb75e58d0cadf53 145 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 10 143 4.6E-5 T 29-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G A616_RS08320 a9a7bb507e62bffa4eb75e58d0cadf53 145 SUPERFAMILY SSF55961 6 143 9.25E-23 T 29-03-2018 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 Pfam PF02911 Formyl transferase, C-terminal domain 206 304 1.3E-31 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 Gene3D G3DSA:3.40.50.170 1 208 4.2E-70 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 305 2.9E-107 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 307 36.696 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 SUPERFAMILY SSF53328 5 208 9.16E-65 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 Pfam PF00551 Formyl transferase 5 182 5.9E-41 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 Gene3D G3DSA:3.10.25.10 209 316 1.4E-34 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A616_RS20780 ebc28871bf01c97ffda7f046e27f1a7e 316 SUPERFAMILY SSF50486 207 308 1.73E-33 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A616_RS29585 e65606fa885aa95b1cd390becc329426 91 Pfam PF04316 Anti-sigma-28 factor, FlgM 34 85 1.9E-14 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal A616_RS29585 e65606fa885aa95b1cd390becc329426 91 Gene3D G3DSA:1.10.287.1160 57 86 7.1E-13 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A616_RS29585 e65606fa885aa95b1cd390becc329426 91 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 89 1.7E-15 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A616_RS29585 e65606fa885aa95b1cd390becc329426 91 SUPERFAMILY SSF101498 1 88 1.7E-17 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A616_RS15455 e9a5b25662cbc9531af9054461b5d990 321 Gene3D G3DSA:3.90.1640.10 1 155 7.3E-4 T 29-03-2018 A616_RS15455 e9a5b25662cbc9531af9054461b5d990 321 Pfam PF02272 DHHA1 domain 235 305 1.7E-6 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A616_RS15455 e9a5b25662cbc9531af9054461b5d990 321 SUPERFAMILY SSF64182 2 314 1.96E-23 T 29-03-2018 A616_RS30690 1043a1d834e3dee246c582bb3fbf6221 96 SUPERFAMILY SSF140500 48 90 1.1E-10 T 29-03-2018 A616_RS30690 1043a1d834e3dee246c582bb3fbf6221 96 Pfam PF09388 Spo0E like sporulation regulatory protein 49 89 8.3E-14 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 SUPERFAMILY SSF52540 7 237 6.52E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 Pfam PF00005 ABC transporter 23 176 1.1E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 Pfam PF00005 ABC transporter 278 432 6.5E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 Gene3D G3DSA:3.40.50.300 4 239 1.4E-46 T 29-03-2018 A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 Gene3D G3DSA:3.40.50.300 259 498 1.4E-35 T 29-03-2018 A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 SMART SM00382 286 481 0.0031 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 SMART SM00382 32 224 1.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS03950 92d9fd9525f63982389f0a5347c63b8c 505 SUPERFAMILY SSF52540 262 484 5.04E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14500 5cbccef81147e814df78b13d10390d99 146 SUPERFAMILY SSF46785 2 138 1.12E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14500 5cbccef81147e814df78b13d10390d99 146 Gene3D G3DSA:1.10.10.10 1 146 9.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14500 5cbccef81147e814df78b13d10390d99 146 Pfam PF02082 Transcriptional regulator 1 81 5.0E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type A616_RS04620 e032ed3054661cd8af3a7a3981ca575b 530 Gene3D G3DSA:3.90.76.10 75 170 1.5E-31 T 29-03-2018 A616_RS04620 e032ed3054661cd8af3a7a3981ca575b 530 SUPERFAMILY SSF53850 47 529 1.49E-135 T 29-03-2018 A616_RS04620 e032ed3054661cd8af3a7a3981ca575b 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 446 3.3E-95 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS04620 e032ed3054661cd8af3a7a3981ca575b 530 PIRSF PIRSF002741 3 529 4.5E-112 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS04620 e032ed3054661cd8af3a7a3981ca575b 530 Gene3D G3DSA:3.10.105.10 302 500 1.0E-48 T 29-03-2018 A616_RS04620 e032ed3054661cd8af3a7a3981ca575b 530 Gene3D G3DSA:3.40.190.10 171 301 4.0E-45 T 29-03-2018 A616_RS25080 af2b15a53b26b9dfb6b75665c60f425f 502 Gene3D G3DSA:3.90.550.10 256 440 2.0E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS25080 af2b15a53b26b9dfb6b75665c60f425f 502 Pfam PF00535 Glycosyl transferase family 2 278 381 2.0E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS25080 af2b15a53b26b9dfb6b75665c60f425f 502 SUPERFAMILY SSF53448 13 165 1.45E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS25080 af2b15a53b26b9dfb6b75665c60f425f 502 SUPERFAMILY SSF53448 274 437 8.04E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS30705 63fbdc8000edf0c43dd8a0b7754cd6c2 313 PIRSF PIRSF018982 66 313 5.1E-87 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS30705 63fbdc8000edf0c43dd8a0b7754cd6c2 313 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 85 311 4.8E-80 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Gene3D G3DSA:2.60.40.1380 361 491 2.6E-4 T 29-03-2018 A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Gene3D G3DSA:3.10.100.10 123 174 3.5E-5 T 29-03-2018 IPR016186 C-type lectin-like/link domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Gene3D G3DSA:3.10.100.10 223 297 0.0025 T 29-03-2018 IPR016186 C-type lectin-like/link domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Gene3D G3DSA:3.10.100.10 77 122 0.021 T 29-03-2018 IPR016186 C-type lectin-like/link domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Gene3D G3DSA:3.10.100.10 175 222 8.9E-5 T 29-03-2018 IPR016186 C-type lectin-like/link domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Pfam PF00395 S-layer homology domain 853 896 0.0014 T 29-03-2018 IPR001119 S-layer homology domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Pfam PF00395 S-layer homology domain 784 827 4.0E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 Pfam PF00395 S-layer homology domain 723 766 2.6E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS07490 8a4f6d32fa70f422b06008b9f0a5a288 906 SUPERFAMILY SSF50985 55 350 9.29E-18 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1571 1641 3.0E-12 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 211 283 1.3E-5 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 590 652 3.8E-9 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 526 589 2.0E-13 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1193 1270 1.8E-7 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1888 1942 6.4E-9 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 421 503 3.9E-8 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 94 169 5.9E-14 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1755 1829 1.5E-6 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1425 1479 3.0E-12 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 284 360 1.4E-6 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1371 1424 1.6E-9 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1005 1075 5.1E-10 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1316 1370 1.2E-6 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 653 712 1.4E-8 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1480 1546 5.4E-12 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1830 1887 6.1E-5 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 844 928 2.8E-6 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 1271 1315 2.2E-4 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Gene3D G3DSA:2.160.20.50 713 777 2.9E-9 T 29-03-2018 A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Pfam PF01391 Collagen triple helix repeat (20 copies) 1880 1937 4.2E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat A616_RS27995 3bc125379e0480b1e1bda0a06b77b3df 2075 Pfam PF01391 Collagen triple helix repeat (20 copies) 107 162 5.6E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat A616_RS16135 afe9a2aafd7e29e0ba31a6ddae077e39 105 Gene3D G3DSA:3.30.110.70 1 102 3.9E-33 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 A616_RS16135 afe9a2aafd7e29e0ba31a6ddae077e39 105 Pfam PF01906 Putative heavy-metal-binding 1 102 9.0E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 A616_RS16135 afe9a2aafd7e29e0ba31a6ddae077e39 105 SUPERFAMILY SSF117782 1 104 5.49E-35 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 A616_RS16135 afe9a2aafd7e29e0ba31a6ddae077e39 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 102 23.885 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 A616_RS28520 cc7804b37f6c13da0c0b9d09f5054bf7 288 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 1 283 18.376 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A616_RS28520 cc7804b37f6c13da0c0b9d09f5054bf7 288 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 56 78 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site A616_RS28520 cc7804b37f6c13da0c0b9d09f5054bf7 288 Pfam PF01040 UbiA prenyltransferase family 18 267 5.0E-62 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A616_RS28520 cc7804b37f6c13da0c0b9d09f5054bf7 288 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 4 281 9.3E-94 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A616_RS17460 77466be84ee7a54d5ccbcd4a4e1dca45 241 Gene3D G3DSA:2.60.40.1220 34 117 2.9E-4 T 29-03-2018 A616_RS17460 77466be84ee7a54d5ccbcd4a4e1dca45 241 Pfam PF13205 Bacterial Ig-like domain 35 133 5.0E-15 T 29-03-2018 IPR032812 SbsA, Ig-like domain A616_RS17460 77466be84ee7a54d5ccbcd4a4e1dca45 241 Gene3D G3DSA:2.60.40.10 135 239 0.49 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS22265 a81361084b052c500518a7b8e2a7e2db 302 Gene3D G3DSA:2.120.10.70 2 146 8.4E-12 T 29-03-2018 A616_RS22265 a81361084b052c500518a7b8e2a7e2db 302 Gene3D G3DSA:2.120.10.70 147 302 2.1E-15 T 29-03-2018 A616_RS22265 a81361084b052c500518a7b8e2a7e2db 302 SUPERFAMILY SSF89372 4 231 9.81E-13 T 29-03-2018 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 SUPERFAMILY SSF64518 1 273 8.63E-85 T 29-03-2018 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 PRINTS PR00207 Flagellin signature 35 52 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 PRINTS PR00207 Flagellin signature 74 93 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 PRINTS PR00207 Flagellin signature 110 133 5.1E-22 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 Gene3D G3DSA:1.20.1330.10 38 245 1.9E-67 T 29-03-2018 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 188 272 3.5E-29 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS29540 933ba04b3e549195a0bb26d9a1bc53c2 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 2.0E-42 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A616_RS02105 ed7fea49fdbe23b75c1ee3272e091728 95 Gene3D G3DSA:2.60.300.12 1 95 4.1E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS02105 ed7fea49fdbe23b75c1ee3272e091728 95 PIRSF PIRSF034852 1 95 2.7E-30 T 29-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 A616_RS02105 ed7fea49fdbe23b75c1ee3272e091728 95 SUPERFAMILY SSF89360 1 94 3.27E-9 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS09165 cce0daef84808295267a7de05f6a770a 262 SUPERFAMILY SSF55874 117 254 2.1E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09165 cce0daef84808295267a7de05f6a770a 262 Gene3D G3DSA:3.30.565.10 39 255 3.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09165 cce0daef84808295267a7de05f6a770a 262 Pfam PF06580 Histidine kinase 57 133 1.8E-20 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 148 16.865 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 TIGRFAM TIGR00077 lspA: signal peptidase II 2 148 1.8E-46 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 Pfam PF01252 Signal peptidase (SPase) II 6 142 4.8E-41 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.7E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 1.7E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS21045 f76885e547a0deaf422ecbd19710b004 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 123 139 1.7E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A616_RS14820 c5ed8e9d1778dcb81eb7474c413963d6 525 Gene3D G3DSA:3.40.190.10 166 299 4.3E-45 T 29-03-2018 A616_RS14820 c5ed8e9d1778dcb81eb7474c413963d6 525 Gene3D G3DSA:3.10.105.10 300 494 4.5E-53 T 29-03-2018 A616_RS14820 c5ed8e9d1778dcb81eb7474c413963d6 525 Gene3D G3DSA:3.90.76.10 63 165 1.2E-32 T 29-03-2018 A616_RS14820 c5ed8e9d1778dcb81eb7474c413963d6 525 SUPERFAMILY SSF53850 44 523 1.19E-141 T 29-03-2018 A616_RS14820 c5ed8e9d1778dcb81eb7474c413963d6 525 PIRSF PIRSF002741 4 525 7.2E-126 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS14820 c5ed8e9d1778dcb81eb7474c413963d6 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 443 8.2E-97 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS05720 a2885ed4f825f4d87f3bfd146acf1c11 274 Gene3D G3DSA:3.60.21.10 6 266 4.6E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS05720 a2885ed4f825f4d87f3bfd146acf1c11 274 SUPERFAMILY SSF56300 11 263 2.9E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS05720 a2885ed4f825f4d87f3bfd146acf1c11 274 Pfam PF00149 Calcineurin-like phosphoesterase 19 223 1.1E-6 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS21500 5146abe0e7d5284dd4f9145d402c7665 152 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 93 3.1E-10 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A616_RS21500 5146abe0e7d5284dd4f9145d402c7665 152 Gene3D G3DSA:2.30.110.10 1 150 3.9E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS21500 5146abe0e7d5284dd4f9145d402c7665 152 SUPERFAMILY SSF50475 9 94 1.46E-12 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS13025 fbe477eb5b2aa89bb3bfb1d5d7a15dce 153 Pfam PF04284 Protein of unknown function (DUF441) 6 144 5.9E-48 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS13025 fbe477eb5b2aa89bb3bfb1d5d7a15dce 153 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 2 147 19.118 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS13025 fbe477eb5b2aa89bb3bfb1d5d7a15dce 153 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 19 111 7.0E-10 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS28555 afb95b472d471e4460ec2121e09353ce 361 Pfam PF03845 Spore germination protein 6 322 2.6E-36 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS28555 afb95b472d471e4460ec2121e09353ce 361 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 355 6.5E-50 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS20240 3b2f37571ac30592112021c46313ff03 75 Pfam PF13083 KH domain 2 74 3.9E-23 T 29-03-2018 A616_RS20240 3b2f37571ac30592112021c46313ff03 75 SUPERFAMILY SSF54814 6 58 3.07E-7 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A616_RS20240 3b2f37571ac30592112021c46313ff03 75 Hamap MF_00088 UPF0109 protein . 1 75 23.813 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 A616_RS20240 3b2f37571ac30592112021c46313ff03 75 Gene3D G3DSA:3.30.300.20 1 75 1.0E-14 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS07080 0e09e3ac2f049880f54e8ee731da2135 176 SUPERFAMILY SSF55729 16 159 1.83E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS07080 0e09e3ac2f049880f54e8ee731da2135 176 Pfam PF13302 Acetyltransferase (GNAT) domain 41 152 2.2E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS07080 0e09e3ac2f049880f54e8ee731da2135 176 Gene3D G3DSA:3.40.630.30 12 174 4.0E-16 T 29-03-2018 A616_RS07755 74b91f446abebf1a28edc5b6b35944d7 326 Gene3D G3DSA:3.30.420.40 3 130 2.0E-23 T 29-03-2018 A616_RS07755 74b91f446abebf1a28edc5b6b35944d7 326 SUPERFAMILY SSF53067 120 313 5.18E-44 T 29-03-2018 A616_RS07755 74b91f446abebf1a28edc5b6b35944d7 326 Gene3D G3DSA:3.30.420.40 131 281 1.7E-44 T 29-03-2018 A616_RS07755 74b91f446abebf1a28edc5b6b35944d7 326 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 11 298 3.2E-28 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A616_RS07755 74b91f446abebf1a28edc5b6b35944d7 326 SUPERFAMILY SSF53067 8 118 9.57E-18 T 29-03-2018 A616_RS06585 d2e70718875f4e28e238dbbddf84cfe7 235 Gene3D G3DSA:1.20.1660.10 1 106 1.7E-7 T 29-03-2018 A616_RS06585 d2e70718875f4e28e238dbbddf84cfe7 235 SUPERFAMILY SSF48371 1 234 1.15E-62 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS06585 d2e70718875f4e28e238dbbddf84cfe7 235 Pfam PF08713 DNA alkylation repair enzyme 6 200 6.3E-19 T 29-03-2018 IPR014825 DNA alkylation repair enzyme A616_RS11350 4a7287d30049eec863d7fdae2dfe4ede 275 Pfam PF00005 ABC transporter 18 167 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS11350 4a7287d30049eec863d7fdae2dfe4ede 275 Gene3D G3DSA:3.40.50.300 2 247 5.0E-63 T 29-03-2018 A616_RS11350 4a7287d30049eec863d7fdae2dfe4ede 275 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS11350 4a7287d30049eec863d7fdae2dfe4ede 275 SUPERFAMILY SSF52540 3 224 2.61E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11350 4a7287d30049eec863d7fdae2dfe4ede 275 SMART SM00382 27 210 9.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30645 f314df53b6abdf53e53306e540d130d6 314 Pfam PF02073 Thermophilic metalloprotease (M29) 120 275 4.9E-12 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS30645 f314df53b6abdf53e53306e540d130d6 314 SUPERFAMILY SSF144052 7 311 1.44E-62 T 29-03-2018 A616_RS07915 9adcf600ea020e9be6f5fbd3934953ff 103 Pfam PF14007 YtpI-like protein 8 94 7.7E-28 T 29-03-2018 IPR025618 YtpI-like protein A616_RS02830 2e7278082c46453531f27c8284652fdd 539 Pfam PF00732 GMC oxidoreductase 27 295 3.2E-21 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 SUPERFAMILY SSF54373 377 465 7.06E-15 T 29-03-2018 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 Gene3D G3DSA:3.50.50.60 9 539 6.9E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 26 48 9.1E-5 T 29-03-2018 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 413 428 9.1E-5 T 29-03-2018 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 SUPERFAMILY SSF51905 474 535 1.88E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 SUPERFAMILY SSF51905 23 323 1.88E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS02830 2e7278082c46453531f27c8284652fdd 539 Pfam PF05199 GMC oxidoreductase 410 525 2.2E-23 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 A616_RS15935 01ead2f20e788c5c8d1b873a5bfb0a8b 154 Gene3D G3DSA:3.40.50.300 2 151 2.3E-8 T 29-03-2018 A616_RS15935 01ead2f20e788c5c8d1b873a5bfb0a8b 154 SUPERFAMILY SSF52540 14 135 7.89E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS15935 01ead2f20e788c5c8d1b873a5bfb0a8b 154 Pfam PF13401 AAA domain 34 132 7.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28410 2d38ff7554c12473f2e118c704c8cf94 392 Pfam PF14094 Domain of unknown function (DUF4272) 177 388 1.4E-76 T 29-03-2018 IPR025368 Protein of unknown function DUF4272 A616_RS31730 87bc02cf35fa68c901e5ebc50505dcd6 240 SMART SM00382 26 213 2.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31730 87bc02cf35fa68c901e5ebc50505dcd6 240 SUPERFAMILY SSF52540 1 235 4.18E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS31730 87bc02cf35fa68c901e5ebc50505dcd6 240 Gene3D G3DSA:3.40.50.300 1 239 3.4E-79 T 29-03-2018 A616_RS31730 87bc02cf35fa68c901e5ebc50505dcd6 240 PIRSF PIRSF039085 1 240 4.7E-119 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS31730 87bc02cf35fa68c901e5ebc50505dcd6 240 Pfam PF00005 ABC transporter 17 165 1.4E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27700 d9f7286d6f94bef926f570f36cbd5bbf 120 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.4E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS27700 d9f7286d6f94bef926f570f36cbd5bbf 120 SUPERFAMILY SSF103481 5 105 1.7E-20 T 29-03-2018 A616_RS05070 3229844f698343dbc781dbb3b27d171e 90 Pfam PF13025 Protein of unknown function (DUF3886) 26 80 5.3E-9 T 29-03-2018 IPR024980 Protein of unknown function DUF3886 A616_RS29450 f195a8e34545bc72eabac447189d8bd5 125 Pfam PF02561 Flagellar protein FliS 7 118 2.3E-36 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A616_RS29450 f195a8e34545bc72eabac447189d8bd5 125 SUPERFAMILY SSF101116 3 121 4.19E-35 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A616_RS29450 f195a8e34545bc72eabac447189d8bd5 125 PIRSF PIRSF039090 1 125 7.4E-32 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A616_RS29450 f195a8e34545bc72eabac447189d8bd5 125 TIGRFAM TIGR00208 fliS: flagellar protein FliS 2 118 4.5E-31 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A616_RS29450 f195a8e34545bc72eabac447189d8bd5 125 Gene3D G3DSA:1.20.120.340 1 120 8.2E-38 T 29-03-2018 A616_RS31670 1456d8255e723655c935cfb583a7dc82 300 Gene3D G3DSA:2.60.120.40 140 287 2.2E-13 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 A616_RS31670 1456d8255e723655c935cfb583a7dc82 300 Gene3D G3DSA:2.160.20.50 97 139 5.2E-8 T 29-03-2018 A616_RS07025 8a8d76ab7ddd996de9cf16d7c44322cc 507 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 446 8.8E-147 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 273 3.2E-95 T 29-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 PIRSF PIRSF000331 1 491 3.5E-158 T 29-03-2018 IPR004925 HpaB/PvcC/4-BUDH A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 Gene3D G3DSA:2.40.110.10 146 275 2.4E-19 T 29-03-2018 A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 SUPERFAMILY SSF56645 3 274 3.4E-81 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 Gene3D G3DSA:1.20.140.10 284 481 2.8E-60 T 29-03-2018 A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 Gene3D G3DSA:1.10.3140.10 3 145 1.2E-43 T 29-03-2018 A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 280 480 6.5E-53 T 29-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal A616_RS16200 5524731f8211b745212b0b7f36f75fc6 495 SUPERFAMILY SSF47203 264 480 6.7E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 SUPERFAMILY SSF53335 88 473 1.25E-88 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 SUPERFAMILY SSF50249 18 80 4.74E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 Pfam PF01938 TRAM domain 23 78 2.5E-14 T 29-03-2018 IPR002792 TRAM domain A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 458 468 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 299 472 1.7E-21 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 Gene3D G3DSA:3.40.50.150 95 474 2.0E-64 T 29-03-2018 A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 Gene3D G3DSA:2.40.50.140 14 94 3.0E-26 T 29-03-2018 A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 36 468 4.1E-171 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A616_RS04080 10444daf1e97395bd4cd375fbd242496 478 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 407 438 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site A616_RS00875 d9e23980dbd1ebcb43ff304788ee4b2a 143 Pfam PF00583 Acetyltransferase (GNAT) family 31 117 3.5E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS00875 d9e23980dbd1ebcb43ff304788ee4b2a 143 Gene3D G3DSA:3.40.630.30 1 139 1.6E-21 T 29-03-2018 A616_RS00875 d9e23980dbd1ebcb43ff304788ee4b2a 143 SUPERFAMILY SSF55729 1 135 2.33E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS14765 464bda665547634b59c5e58e554ec43a 436 Gene3D G3DSA:1.10.10.10 360 435 2.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14765 464bda665547634b59c5e58e554ec43a 436 SUPERFAMILY SSF46785 378 428 1.88E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS11820 a71804994b07e831ea3146646601baf0 225 SUPERFAMILY SSF100950 12 223 2.51E-64 T 29-03-2018 A616_RS11820 a71804994b07e831ea3146646601baf0 225 SMART SM00882 14 210 2.6E-57 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS11820 a71804994b07e831ea3146646601baf0 225 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 13 217 2.6E-87 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 A616_RS11820 a71804994b07e831ea3146646601baf0 225 Pfam PF01144 Coenzyme A transferase 14 207 1.2E-33 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS11820 a71804994b07e831ea3146646601baf0 225 Gene3D G3DSA:3.40.1080.10 11 222 1.8E-58 T 29-03-2018 A616_RS20870 0348c752f1bd1aac786337b01627ca13 56 Pfam PF14168 YjzC-like protein 2 55 4.9E-23 T 29-03-2018 IPR025549 YjzC-like protein A616_RS20695 fafa69c69de6cc4edfa89f4f7577073d 574 Pfam PF13684 Dihydroxyacetone kinase family 244 574 5.5E-122 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain A616_RS20695 fafa69c69de6cc4edfa89f4f7577073d 574 SMART SM01121 244 574 1.6E-175 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain A616_RS20695 fafa69c69de6cc4edfa89f4f7577073d 574 Pfam PF02734 DAK2 domain 36 200 4.0E-43 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A616_RS20695 fafa69c69de6cc4edfa89f4f7577073d 574 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 574 4.0E-205 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV A616_RS20695 fafa69c69de6cc4edfa89f4f7577073d 574 SMART SM01120 36 201 1.1E-70 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A616_RS20695 fafa69c69de6cc4edfa89f4f7577073d 574 SUPERFAMILY SSF101473 6 203 2.62E-45 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 A616_RS16335 3686385c1f1602cc3bcf2766c1723b16 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 4.9E-107 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A616_RS16335 3686385c1f1602cc3bcf2766c1723b16 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 47.771 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A616_RS16335 3686385c1f1602cc3bcf2766c1723b16 235 SUPERFAMILY SSF53167 2 233 1.18E-92 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS16335 3686385c1f1602cc3bcf2766c1723b16 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 29-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A616_RS16335 3686385c1f1602cc3bcf2766c1723b16 235 Pfam PF01048 Phosphorylase superfamily 16 221 2.7E-40 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS16335 3686385c1f1602cc3bcf2766c1723b16 235 Gene3D G3DSA:3.40.50.1580 8 235 1.6E-53 T 29-03-2018 A616_RS28335 ca65f3d0a33272337d936af5da955313 154 Gene3D G3DSA:3.40.630.30 1 154 3.1E-24 T 29-03-2018 A616_RS28335 ca65f3d0a33272337d936af5da955313 154 Pfam PF00583 Acetyltransferase (GNAT) family 42 131 1.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS28335 ca65f3d0a33272337d936af5da955313 154 SUPERFAMILY SSF55729 9 154 1.41E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS00435 66bced0edf74a498c6462520fb12df61 193 SUPERFAMILY SSF64307 9 80 1.7E-23 T 29-03-2018 IPR001455 TusA-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 Pfam PF01206 Sulfurtransferase TusA 11 80 1.3E-21 T 29-03-2018 IPR001455 TusA-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 Gene3D G3DSA:3.40.250.10 78 191 4.0E-25 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 Gene3D G3DSA:3.30.110.40 1 77 5.5E-27 T 29-03-2018 IPR001455 TusA-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 SUPERFAMILY SSF52821 88 187 5.11E-29 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 SMART SM00450 97 192 1.5E-20 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 13 37 - T 29-03-2018 IPR001455 TusA-like domain A616_RS00435 66bced0edf74a498c6462520fb12df61 193 Pfam PF00581 Rhodanese-like domain 97 187 1.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS15870 ac242653e9013003ca72f045413d74e4 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 463 2.0E-82 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS15870 ac242653e9013003ca72f045413d74e4 543 Gene3D G3DSA:3.40.190.10 176 309 1.1E-34 T 29-03-2018 A616_RS15870 ac242653e9013003ca72f045413d74e4 543 Gene3D G3DSA:3.90.76.10 65 175 3.3E-31 T 29-03-2018 A616_RS15870 ac242653e9013003ca72f045413d74e4 543 SUPERFAMILY SSF53850 39 535 9.05E-133 T 29-03-2018 A616_RS15870 ac242653e9013003ca72f045413d74e4 543 PIRSF PIRSF002741 2 538 1.1E-124 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS15870 ac242653e9013003ca72f045413d74e4 543 Gene3D G3DSA:3.10.105.10 310 513 1.7E-58 T 29-03-2018 A616_RS06605 0aafa9cf8fc81aded88f356faac010d3 87 Pfam PF13619 KTSC domain 25 81 5.5E-16 T 29-03-2018 IPR025309 KTSC domain A616_RS27230 a9d6aa8019920b92d9b518c9147642fc 266 Gene3D G3DSA:3.40.50.1820 8 266 3.1E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS27230 a9d6aa8019920b92d9b518c9147642fc 266 SUPERFAMILY SSF53474 10 264 9.07E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS27230 a9d6aa8019920b92d9b518c9147642fc 266 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 107 137 - T 29-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 A616_RS27230 a9d6aa8019920b92d9b518c9147642fc 266 Pfam PF00326 Prolyl oligopeptidase family 72 264 1.5E-25 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A616_RS05560 0464e392ccdfb32d36938a054a82f800 244 Pfam PF03591 AzlC protein 29 169 6.9E-39 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease A616_RS06935 f60c73af473658545d7fc05296d62996 430 Pfam PF10117 McrBC 5-methylcytosine restriction system component 56 378 2.4E-72 T 29-03-2018 IPR019292 5-methylcytosine restriction system component A616_RS09520 e925debd645d4c85abf986126893a4e2 222 Pfam PF08713 DNA alkylation repair enzyme 11 221 1.1E-66 T 29-03-2018 IPR014825 DNA alkylation repair enzyme A616_RS09520 e925debd645d4c85abf986126893a4e2 222 SUPERFAMILY SSF48371 14 221 4.99E-54 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS09520 e925debd645d4c85abf986126893a4e2 222 Gene3D G3DSA:1.25.40.290 130 222 1.1E-22 T 29-03-2018 A616_RS09520 e925debd645d4c85abf986126893a4e2 222 Gene3D G3DSA:1.20.1660.10 8 127 4.5E-30 T 29-03-2018 A616_RS03615 e6c76040bcd8e01d6dbd96efeb8de7aa 402 Gene3D G3DSA:1.20.1250.20 203 384 8.4E-29 T 29-03-2018 A616_RS03615 e6c76040bcd8e01d6dbd96efeb8de7aa 402 Pfam PF07690 Major Facilitator Superfamily 17 240 1.3E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS03615 e6c76040bcd8e01d6dbd96efeb8de7aa 402 SUPERFAMILY SSF103473 6 384 1.28E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS03615 e6c76040bcd8e01d6dbd96efeb8de7aa 402 Gene3D G3DSA:1.20.1250.20 2 202 2.0E-25 T 29-03-2018 A616_RS27610 bab6bea0211ba395bad7868a1dd62d78 379 PIRSF PIRSF037259 3 379 1.3E-78 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A616_RS27610 bab6bea0211ba395bad7868a1dd62d78 379 Pfam PF05975 Bacterial ABC transporter protein EcsB 7 378 6.1E-87 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 A616_RS21845 a798b9512e9b358dec5ceccab8a86b8a 198 Gene3D G3DSA:3.10.450.40 57 116 4.7E-14 T 29-03-2018 A616_RS21845 a798b9512e9b358dec5ceccab8a86b8a 198 Gene3D G3DSA:3.10.450.40 137 194 1.1E-16 T 29-03-2018 A616_RS21845 a798b9512e9b358dec5ceccab8a86b8a 198 Pfam PF03413 Peptidase propeptide and YPEB domain 136 194 1.1E-15 T 29-03-2018 IPR025711 PepSY domain A616_RS21845 a798b9512e9b358dec5ceccab8a86b8a 198 Pfam PF03413 Peptidase propeptide and YPEB domain 57 110 6.1E-12 T 29-03-2018 IPR025711 PepSY domain A616_RS21430 82cb9ad02830dfc64d7159da3f5bb457 232 Gene3D G3DSA:1.10.10.10 1 80 2.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21430 82cb9ad02830dfc64d7159da3f5bb457 232 Gene3D G3DSA:3.30.1380.20 81 229 2.2E-14 T 29-03-2018 A616_RS21430 82cb9ad02830dfc64d7159da3f5bb457 232 SUPERFAMILY SSF46785 1 209 3.67E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS21430 82cb9ad02830dfc64d7159da3f5bb457 232 Pfam PF12840 Helix-turn-helix domain 7 64 1.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00845 67d5173d67acac2e6cbe673e4327f4e1 256 Gene3D G3DSA:3.40.50.300 1 255 2.0E-64 T 29-03-2018 A616_RS00845 67d5173d67acac2e6cbe673e4327f4e1 256 SUPERFAMILY SSF52540 9 239 5.9E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00845 67d5173d67acac2e6cbe673e4327f4e1 256 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS00845 67d5173d67acac2e6cbe673e4327f4e1 256 Pfam PF00005 ABC transporter 26 174 5.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS00845 67d5173d67acac2e6cbe673e4327f4e1 256 SMART SM00382 35 255 4.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS24360 9946498bdc4336246d94eb56d591c7ad 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 271 5.7E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS24360 9946498bdc4336246d94eb56d591c7ad 284 Gene3D G3DSA:1.10.3720.10 6 283 1.1E-48 T 29-03-2018 A616_RS24360 9946498bdc4336246d94eb56d591c7ad 284 SUPERFAMILY SSF161098 4 273 9.81E-59 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS11085 87a3632410adfcf639edccadeb42191a 289 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 8 278 3.9E-90 T 29-03-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG A616_RS11085 87a3632410adfcf639edccadeb42191a 289 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 30 277 5.4E-63 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related A616_RS26065 3aa8f1bb95c237fdebaef2de41db18fc 443 Gene3D G3DSA:3.40.190.10 36 165 6.2E-25 T 29-03-2018 A616_RS26065 3aa8f1bb95c237fdebaef2de41db18fc 443 SUPERFAMILY SSF53850 22 436 9.88E-74 T 29-03-2018 A616_RS26065 3aa8f1bb95c237fdebaef2de41db18fc 443 Gene3D G3DSA:3.40.190.10 166 371 2.3E-38 T 29-03-2018 A616_RS26065 3aa8f1bb95c237fdebaef2de41db18fc 443 Pfam PF01547 Bacterial extracellular solute-binding protein 48 347 6.5E-41 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 A616_RS26410 12992c31bed9a301adbdd0139b8b0f64 306 Gene3D G3DSA:3.40.50.1820 49 304 1.9E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS26410 12992c31bed9a301adbdd0139b8b0f64 306 Pfam PF00326 Prolyl oligopeptidase family 109 304 3.0E-10 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A616_RS26410 12992c31bed9a301adbdd0139b8b0f64 306 SUPERFAMILY SSF53474 14 300 1.22E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS20965 eef8fa11d5672229af828d42038a78fe 171 SUPERFAMILY SSF88874 1 165 4.32E-47 T 29-03-2018 A616_RS20965 eef8fa11d5672229af828d42038a78fe 171 Gene3D G3DSA:4.10.1070.10 55 153 6.6E-5 T 29-03-2018 A616_RS20965 eef8fa11d5672229af828d42038a78fe 171 Gene3D G3DSA:3.90.1340.10 1 54 8.8E-24 T 29-03-2018 IPR011083 Phage tail collar domain A616_RS20965 eef8fa11d5672229af828d42038a78fe 171 Pfam PF07484 Phage Tail Collar Domain 7 63 7.7E-29 T 29-03-2018 IPR011083 Phage tail collar domain A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 232 16.447 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 Pfam PF00902 Sec-independent protein translocase protein (TatC) 9 213 1.7E-52 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 7 218 2.9E-57 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 6 33 1.1E-37 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 146 174 1.1E-37 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 95 121 1.1E-37 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 77 95 1.1E-37 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A616_RS01135 a1526a9fbbb80955b107ab8b08a95f3a 244 ProSitePatterns PS01218 TatC family signature. 146 165 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A616_RS16290 ef81bb5bef4f1d8eda1fe76b45b94754 215 Gene3D G3DSA:3.40.109.10 2 213 5.7E-47 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS16290 ef81bb5bef4f1d8eda1fe76b45b94754 215 SUPERFAMILY SSF55469 10 212 4.32E-54 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS16290 ef81bb5bef4f1d8eda1fe76b45b94754 215 Pfam PF00881 Nitroreductase family 15 193 5.1E-30 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS11110 92ae2c6fb5a3e0da19f00faf707e65d0 240 Gene3D G3DSA:3.40.50.1220 1 240 2.2E-64 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS11110 92ae2c6fb5a3e0da19f00faf707e65d0 240 SUPERFAMILY SSF52467 2 234 4.25E-77 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS11110 92ae2c6fb5a3e0da19f00faf707e65d0 240 Pfam PF02146 Sir2 family 19 189 3.5E-48 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 A616_RS25805 5e5e9e520bcb2eda56f5641840aa9ada 822 SUPERFAMILY SSF49373 214 260 1.02E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS25805 5e5e9e520bcb2eda56f5641840aa9ada 822 Gene3D G3DSA:2.60.40.1080 173 263 1.6E-8 T 29-03-2018 A616_RS25805 5e5e9e520bcb2eda56f5641840aa9ada 822 Gene3D G3DSA:1.20.1270.90 346 437 0.47 T 29-03-2018 A616_RS15955 8730adfbfdba84248447013ff1b534ee 159 Pfam PF07849 Protein of unknown function (DUF1641) 119 154 8.8E-16 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 A616_RS19920 3e389bba92a556afefd4ff90154d57ab 158 SMART SM00260 8 145 7.1E-40 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS19920 3e389bba92a556afefd4ff90154d57ab 158 Gene3D G3DSA:2.30.30.40 94 139 1.4E-19 T 29-03-2018 A616_RS19920 3e389bba92a556afefd4ff90154d57ab 158 SUPERFAMILY SSF50341 9 149 2.22E-39 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS19920 3e389bba92a556afefd4ff90154d57ab 158 Gene3D G3DSA:2.40.50.180 2 33 0.23 T 29-03-2018 A616_RS19920 3e389bba92a556afefd4ff90154d57ab 158 Gene3D G3DSA:2.40.50.180 34 93 5.1E-23 T 29-03-2018 A616_RS19920 3e389bba92a556afefd4ff90154d57ab 158 Pfam PF01584 CheW-like domain 13 148 4.3E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A616_RS12430 c290915f4651265f5d1a96cb4c6f49cf 621 Gene3D G3DSA:3.20.20.220 298 620 6.3E-70 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like A616_RS12430 c290915f4651265f5d1a96cb4c6f49cf 621 Gene3D G3DSA:3.20.20.330 2 297 8.2E-75 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A616_RS12430 c290915f4651265f5d1a96cb4c6f49cf 621 SUPERFAMILY SSF51730 329 610 6.08E-71 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like A616_RS12430 c290915f4651265f5d1a96cb4c6f49cf 621 Pfam PF02574 Homocysteine S-methyltransferase 17 287 6.9E-51 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A616_RS12430 c290915f4651265f5d1a96cb4c6f49cf 621 SUPERFAMILY SSF82282 6 372 1.96E-91 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A616_RS12430 c290915f4651265f5d1a96cb4c6f49cf 621 Pfam PF02219 Methylenetetrahydrofolate reductase 327 584 7.5E-31 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 A616_RS02695 91cca96b2080d2ac95d0ce963315d480 221 SUPERFAMILY SSF161098 12 208 4.71E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS02695 91cca96b2080d2ac95d0ce963315d480 221 Gene3D G3DSA:1.10.3720.10 6 221 7.7E-38 T 29-03-2018 A616_RS02695 91cca96b2080d2ac95d0ce963315d480 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 214 2.3E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25800 79a43b9c2c935db240328e712f08c0ea 296 SUPERFAMILY SSF55729 22 92 4.25E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25800 79a43b9c2c935db240328e712f08c0ea 296 Gene3D G3DSA:3.40.630.30 102 271 3.6E-6 T 29-03-2018 A616_RS25800 79a43b9c2c935db240328e712f08c0ea 296 SUPERFAMILY SSF55729 177 269 1.95E-6 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25800 79a43b9c2c935db240328e712f08c0ea 296 Gene3D G3DSA:3.40.630.30 3 95 5.4E-8 T 29-03-2018 A616_RS25800 79a43b9c2c935db240328e712f08c0ea 296 Pfam PF00583 Acetyltransferase (GNAT) family 21 93 5.4E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25360 c6e64d562d0c74c08d0bf381f5cecf6e 121 TIGRFAM TIGR03987 TIGR03987: TIGR03987 family protein 2 118 1.0E-50 T 29-03-2018 IPR023813 Conserved hypothetical protein CHP03987 A616_RS16870 08a44a49d2864691a33443cbf7b8bfea 379 Pfam PF08210 APOBEC-like N-terminal domain 181 289 2.2E-6 T 29-03-2018 IPR013158 APOBEC-like, N-terminal GO:0008270|GO:0016814 A616_RS08240 4b55eaca3c3bc0803d236c3a75eeccc3 122 Pfam PF13788 Domain of unknown function (DUF4180) 12 118 4.1E-42 T 29-03-2018 IPR025438 Domain of unknown function DUF4180 A616_RS18305 2ebd0ccf9744ea8e315781dde5dcb34e 114 Pfam PF03692 Putative zinc- or iron-chelating domain 5 77 1.4E-10 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A616_RS28560 b50ae472de3857ca661617a3eaef2216 305 SUPERFAMILY SSF110581 3 301 5.75E-116 T 29-03-2018 A616_RS28560 b50ae472de3857ca661617a3eaef2216 305 Gene3D G3DSA:3.40.1790.10 1 303 3.1E-139 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A616_RS28560 b50ae472de3857ca661617a3eaef2216 305 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 302 43.504 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A616_RS28560 b50ae472de3857ca661617a3eaef2216 305 Pfam PF04227 Indigoidine synthase A like protein 10 299 1.5E-132 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 A616_RS03220 886cefe67585336b0c48ffade6168d2b 190 SUPERFAMILY SSF55729 11 183 9.56E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS03220 886cefe67585336b0c48ffade6168d2b 190 Pfam PF13302 Acetyltransferase (GNAT) domain 16 159 6.9E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS03220 886cefe67585336b0c48ffade6168d2b 190 Gene3D G3DSA:3.40.630.30 1 186 2.9E-21 T 29-03-2018 A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 Pfam PF00248 Aldo/keto reductase family 4 304 1.4E-64 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 SUPERFAMILY SSF51430 2 307 3.8E-69 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 Gene3D G3DSA:3.20.20.100 1 309 2.7E-69 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 PRINTS PR00069 Aldo-keto reductase signature 96 114 1.9E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 PRINTS PR00069 Aldo-keto reductase signature 127 144 1.9E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS25300 df3673f2c5815ab4894c6cca28754478 313 PRINTS PR00069 Aldo-keto reductase signature 38 62 1.9E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS19970 21bb7e13eff925ab58797f69832439cd 226 Pfam PF04347 Flagellar biosynthesis protein, FliO 91 158 3.0E-10 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 A616_RS16760 935ebf18286fafd5544e5f3ec0bbb240 216 Gene3D G3DSA:3.30.460.10 11 213 0.0011 T 29-03-2018 A616_RS10435 8b19d474b94f58966476da90e673b3d2 412 Pfam PF13581 Histidine kinase-like ATPase domain 289 404 3.6E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS10435 8b19d474b94f58966476da90e673b3d2 412 SUPERFAMILY SSF55874 314 402 1.31E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS10435 8b19d474b94f58966476da90e673b3d2 412 Gene3D G3DSA:3.30.565.10 283 410 6.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 225 246 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 136 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 163 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 259 277 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 6.0E-48 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 Gene3D G3DSA:3.50.50.60 173 304 1.6E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 SUPERFAMILY SSF51905 2 299 1.48E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 285 9.9E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 271 3.9E-24 T 29-03-2018 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.9E-24 T 29-03-2018 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.9E-24 T 29-03-2018 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.9E-24 T 29-03-2018 A616_RS07785 a37791fe943193f36acb8efb75e7fd17 307 Gene3D G3DSA:3.50.50.60 1 172 4.5E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 Gene3D G3DSA:3.90.180.10 1 152 1.2E-41 T 29-03-2018 A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 Gene3D G3DSA:3.40.50.720 153 245 1.8E-18 T 29-03-2018 A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 109 1.5E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 SUPERFAMILY SSF51735 123 294 1.2E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 Gene3D G3DSA:3.90.180.10 250 321 1.2E-6 T 29-03-2018 A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 Pfam PF13602 Zinc-binding dehydrogenase 192 317 1.4E-24 T 29-03-2018 A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 SUPERFAMILY SSF50129 1 157 3.96E-32 T 29-03-2018 IPR011032 GroES-like A616_RS23180 6ff630c3937d3e8871c63f934cfaa925 321 SMART SM00829 10 317 8.9E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A616_RS27875 21d8e1a401f947059d611dd985c1431f 354 SUPERFAMILY SSF52540 11 155 3.45E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27875 21d8e1a401f947059d611dd985c1431f 354 Gene3D G3DSA:3.40.50.300 7 161 1.4E-17 T 29-03-2018 A616_RS27875 21d8e1a401f947059d611dd985c1431f 354 Pfam PF07728 AAA domain (dynein-related subfamily) 24 150 2.8E-11 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A616_RS23050 fe26fd800c24361c10ef6197fd864e96 92 Pfam PF13365 Trypsin-like peptidase domain 5 62 1.3E-11 T 29-03-2018 A616_RS23050 fe26fd800c24361c10ef6197fd864e96 92 PRINTS PR00834 HtrA/DegQ protease family signature 33 50 1.4E-11 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS23050 fe26fd800c24361c10ef6197fd864e96 92 PRINTS PR00834 HtrA/DegQ protease family signature 55 72 1.4E-11 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A616_RS23050 fe26fd800c24361c10ef6197fd864e96 92 Gene3D G3DSA:2.40.10.10 1 90 1.9E-27 T 29-03-2018 A616_RS23050 fe26fd800c24361c10ef6197fd864e96 92 SUPERFAMILY SSF50494 4 89 1.06E-26 T 29-03-2018 IPR009003 Peptidase S1, PA clan A616_RS07675 ff6f634bee2f41876d8efbf475a22c04 156 SUPERFAMILY SSF109854 1 143 1.98E-16 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS07675 ff6f634bee2f41876d8efbf475a22c04 156 Pfam PF12867 DinB superfamily 14 140 8.2E-10 T 29-03-2018 IPR024775 DinB-like domain A616_RS07675 ff6f634bee2f41876d8efbf475a22c04 156 Gene3D G3DSA:1.20.120.450 1 155 1.5E-16 T 29-03-2018 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 Gene3D G3DSA:3.20.20.70 1 218 6.8E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 37.935 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 SUPERFAMILY SSF51569 1 213 5.65E-86 T 29-03-2018 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 SMART SM01133 2 213 1.9E-105 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 Pfam PF01791 DeoC/LacD family aldolase 6 209 1.7E-21 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 5.4E-92 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A616_RS11500 0b338a6cf281b30d3f463d1d710eb5eb 221 PIRSF PIRSF001357 1 219 1.3E-78 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 Gene3D G3DSA:3.30.450.40 556 616 0.077 T 29-03-2018 IPR029016 GAF domain-like A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 Gene3D G3DSA:3.40.50.720 1 163 1.2E-30 T 29-03-2018 A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 SUPERFAMILY SSF51735 1 304 8.89E-89 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 Gene3D G3DSA:3.30.450.40 440 545 0.037 T 29-03-2018 IPR029016 GAF domain-like A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 Gene3D G3DSA:3.90.25.10 164 314 6.3E-41 T 29-03-2018 A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 228 6.2E-60 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS03350 1b8de8b705731e3c21ca4eb739c0a80e 734 SUPERFAMILY SSF55781 485 612 1.26E-7 T 29-03-2018 IPR029016 GAF domain-like A616_RS12435 bd525e26a8b002df147c9c21707ee216 329 SUPERFAMILY SSF56112 3 300 9.91E-39 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS12435 bd525e26a8b002df147c9c21707ee216 329 Pfam PF01636 Phosphotransferase enzyme family 31 265 4.9E-17 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS12435 bd525e26a8b002df147c9c21707ee216 329 Gene3D G3DSA:3.90.1200.10 98 327 3.1E-26 T 29-03-2018 A616_RS12435 bd525e26a8b002df147c9c21707ee216 329 Gene3D G3DSA:3.30.200.20 1 93 1.7E-10 T 29-03-2018 A616_RS19645 a7eeffc260c45154aacfcb698fee5a27 299 SUPERFAMILY SSF47413 3 72 1.41E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS19645 a7eeffc260c45154aacfcb698fee5a27 299 Pfam PF13413 Helix-turn-helix domain 8 67 1.2E-22 T 29-03-2018 A616_RS19645 a7eeffc260c45154aacfcb698fee5a27 299 Gene3D G3DSA:1.10.260.40 1 82 1.1E-9 T 29-03-2018 A616_RS19645 a7eeffc260c45154aacfcb698fee5a27 299 Pfam PF13464 Domain of unknown function (DUF4115) 224 283 1.4E-8 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 A616_RS28710 c269dd9f8cd4489515a234ed1efa7db5 357 Pfam PF06271 RDD family 40 161 6.3E-15 T 29-03-2018 IPR010432 RDD A616_RS28710 c269dd9f8cd4489515a234ed1efa7db5 357 Gene3D G3DSA:3.40.1000.10 213 356 2.2E-17 T 29-03-2018 A616_RS27045 da634efab115bd605f0a36cec6d90a83 335 Pfam PF01384 Phosphate transporter family 22 324 1.3E-91 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A616_RS19860 6134e4c419d2e40bfdee95a222351121 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 4.7E-72 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A616_RS19860 6134e4c419d2e40bfdee95a222351121 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.388 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A616_RS19860 6134e4c419d2e40bfdee95a222351121 185 Gene3D G3DSA:1.10.132.20 75 185 1.3E-37 T 29-03-2018 A616_RS19860 6134e4c419d2e40bfdee95a222351121 185 Gene3D G3DSA:1.10.132.20 3 74 1.5E-12 T 29-03-2018 A616_RS19860 6134e4c419d2e40bfdee95a222351121 185 SUPERFAMILY SSF55194 4 184 5.49E-72 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A616_RS19860 6134e4c419d2e40bfdee95a222351121 185 Pfam PF01765 Ribosome recycling factor 20 183 6.4E-67 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A616_RS25105 1788f87ef358fa507071e83956e1a757 250 Gene3D G3DSA:3.30.70.1100 141 246 6.0E-29 T 29-03-2018 A616_RS25105 1788f87ef358fa507071e83956e1a757 250 Gene3D G3DSA:3.30.70.1030 6 138 7.8E-42 T 29-03-2018 A616_RS25105 1788f87ef358fa507071e83956e1a757 250 Pfam PF06778 Chlorite dismutase 35 238 4.4E-75 T 29-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase A616_RS25105 1788f87ef358fa507071e83956e1a757 250 SUPERFAMILY SSF54909 4 248 2.95E-88 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS10075 878ac215adb62fb9cae122e6b634c4e4 363 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 6 359 5.4E-151 T 29-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 A616_RS10075 878ac215adb62fb9cae122e6b634c4e4 363 Gene3D G3DSA:3.90.25.10 204 362 1.1E-29 T 29-03-2018 A616_RS10075 878ac215adb62fb9cae122e6b634c4e4 363 Pfam PF16363 GDP-mannose 4,6 dehydratase 13 332 6.2E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10075 878ac215adb62fb9cae122e6b634c4e4 363 SUPERFAMILY SSF51735 4 348 4.35E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10075 878ac215adb62fb9cae122e6b634c4e4 363 Gene3D G3DSA:3.40.50.720 3 203 2.2E-30 T 29-03-2018 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 SUPERFAMILY SSF161070 5 441 6.41E-133 T 29-03-2018 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 7.1E-13 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 7.1E-13 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 7.1E-13 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 1.3E-26 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A616_RS12680 b55d99617cf052cbf0fa17da73103d08 444 Pfam PF00209 Sodium:neurotransmitter symporter family 141 439 6.2E-31 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A616_RS20330 bf83211511e687c054be6a6af176fe73 56 SUPERFAMILY SSF57829 1 55 1.89E-22 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A616_RS20330 bf83211511e687c054be6a6af176fe73 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.3E-27 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20330 bf83211511e687c054be6a6af176fe73 56 Pfam PF01783 Ribosomal L32p protein family 2 55 5.1E-26 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20330 bf83211511e687c054be6a6af176fe73 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 19.587 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS31230 b8b064a7ad256ef287bebc072fdf4062 244 SUPERFAMILY SSF56281 4 242 5.63E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS31230 b8b064a7ad256ef287bebc072fdf4062 244 Pfam PF00753 Metallo-beta-lactamase superfamily 26 221 8.1E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS31230 b8b064a7ad256ef287bebc072fdf4062 244 SMART SM00849 22 227 1.6E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS31230 b8b064a7ad256ef287bebc072fdf4062 244 Gene3D G3DSA:3.60.15.10 14 232 9.7E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 SUPERFAMILY SSF46689 167 218 4.66E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 Gene3D G3DSA:1.10.10.60 235 273 4.6E-14 T 29-03-2018 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 263 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 267 6.7E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 251 6.7E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 Gene3D G3DSA:3.90.1240.10 91 234 2.3E-21 T 29-03-2018 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 SUPERFAMILY SSF51215 14 151 6.54E-6 T 29-03-2018 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 SUPERFAMILY SSF46689 220 272 1.25E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 SMART SM00342 184 267 3.4E-29 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 Gene3D G3DSA:2.60.120.10 17 90 0.0012 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS32055 816e3b57a4eb4ec5096f113af2620180 275 Pfam PF12833 Helix-turn-helix domain 190 268 4.2E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS10105 f09551d8e0509c87970ca38cd4b42b12 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 239 2.2E-59 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS10105 f09551d8e0509c87970ca38cd4b42b12 318 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 5 308 44.196 T 29-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 A616_RS10105 f09551d8e0509c87970ca38cd4b42b12 318 SUPERFAMILY SSF51735 3 312 7.2E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10105 f09551d8e0509c87970ca38cd4b42b12 318 Gene3D G3DSA:3.90.25.10 164 315 1.4E-44 T 29-03-2018 A616_RS10105 f09551d8e0509c87970ca38cd4b42b12 318 Gene3D G3DSA:3.40.50.720 4 163 1.4E-15 T 29-03-2018 A616_RS22305 b7f7c1eeb733f2e55fefb058110338fe 143 Gene3D G3DSA:1.10.3680.10 6 143 4.2E-15 T 29-03-2018 IPR029024 TerB-like A616_RS22305 b7f7c1eeb733f2e55fefb058110338fe 143 Pfam PF05099 Tellurite resistance protein TerB 13 121 1.8E-7 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal A616_RS22305 b7f7c1eeb733f2e55fefb058110338fe 143 SUPERFAMILY SSF158682 9 130 4.97E-20 T 29-03-2018 A616_RS07030 eb355d24ec1777893460e12664408267 261 Pfam PF08241 Methyltransferase domain 50 145 8.4E-24 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS07030 eb355d24ec1777893460e12664408267 261 SUPERFAMILY SSF53335 11 225 6.97E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS07030 eb355d24ec1777893460e12664408267 261 Gene3D G3DSA:3.40.50.150 25 261 6.0E-45 T 29-03-2018 A616_RS24780 7aa79c2b57a3142a9b29b5d1c3598df3 145 SUPERFAMILY SSF81442 3 121 9.03E-11 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS24780 7aa79c2b57a3142a9b29b5d1c3598df3 145 Gene3D G3DSA:1.20.210.10 1 136 7.0E-10 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 SUPERFAMILY SSF55729 50 165 1.63E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 PRINTS PR01754 Streptothricin acetyltransferase signature 126 141 2.6E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 PRINTS PR01754 Streptothricin acetyltransferase signature 102 117 2.6E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 PRINTS PR01754 Streptothricin acetyltransferase signature 147 163 2.6E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 PRINTS PR01754 Streptothricin acetyltransferase signature 170 183 2.6E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 Gene3D G3DSA:3.40.630.30 35 184 5.7E-28 T 29-03-2018 A616_RS11005 f7226f68556cb815ce58239b596eaa9d 184 Pfam PF00583 Acetyltransferase (GNAT) family 53 155 7.9E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS28550 4979b375a7bb9d8ab293353d651b9c7a 374 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 3 365 3.3E-79 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS28550 4979b375a7bb9d8ab293353d651b9c7a 374 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 203 361 2.1E-33 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 Pfam PF03063 Prismane/CO dehydrogenase family 79 424 3.2E-102 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 Pfam PF03063 Prismane/CO dehydrogenase family 1 80 5.2E-16 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 Gene3D G3DSA:3.40.50.2030 253 430 1.6E-52 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 428 16.597 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 SUPERFAMILY SSF56821 1 427 4.06E-147 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 Gene3D G3DSA:1.20.1270.20 28 111 2.5E-31 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 23 427 8.8E-168 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26145 13a34cb50c430c3e0258f92846748984 431 Gene3D G3DSA:3.40.50.2030 114 252 5.7E-62 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A616_RS26755 508b66f3548780a736d794ca8f4bd3a1 387 Gene3D G3DSA:1.10.150.130 50 173 4.2E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS26755 508b66f3548780a736d794ca8f4bd3a1 387 Gene3D G3DSA:3.30.160.20 6 41 0.0016 T 29-03-2018 A616_RS26755 508b66f3548780a736d794ca8f4bd3a1 387 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 58 112 1.6E-15 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS26755 508b66f3548780a736d794ca8f4bd3a1 387 SUPERFAMILY SSF56349 56 373 6.18E-60 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS26755 508b66f3548780a736d794ca8f4bd3a1 387 Pfam PF00589 Phage integrase family 176 367 9.7E-23 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS26755 508b66f3548780a736d794ca8f4bd3a1 387 Gene3D G3DSA:1.10.443.10 174 386 2.9E-35 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 SUPERFAMILY SSF48498 93 190 7.69E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 5.1E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 SUPERFAMILY SSF46689 4 65 4.0E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 Gene3D G3DSA:1.10.10.60 5 43 3.6E-19 T 29-03-2018 A616_RS17735 24cd5a858f59696a33dcc971a9b41545 191 Gene3D G3DSA:1.10.10.60 44 143 6.6E-10 T 29-03-2018 A616_RS23425 cf9d8d34201ca407ee3d9f41c9485a19 231 SUPERFAMILY SSF52540 45 217 6.98E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS23425 cf9d8d34201ca407ee3d9f41c9485a19 231 Gene3D G3DSA:3.40.50.300 27 224 1.2E-33 T 29-03-2018 A616_RS23425 cf9d8d34201ca407ee3d9f41c9485a19 231 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 46 215 9.1E-10 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A616_RS23425 cf9d8d34201ca407ee3d9f41c9485a19 231 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 27 227 1.8E-54 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 A616_RS08845 d448283244b697d87589420a5aeb6ae0 151 SUPERFAMILY SSF158682 16 150 4.32E-22 T 29-03-2018 A616_RS08845 d448283244b697d87589420a5aeb6ae0 151 Gene3D G3DSA:1.10.3680.10 4 151 1.1E-18 T 29-03-2018 IPR029024 TerB-like A616_RS08845 d448283244b697d87589420a5aeb6ae0 151 Pfam PF05099 Tellurite resistance protein TerB 18 150 7.6E-27 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal A616_RS28135 d1ff7423ae2edc795e64ccb97ef9e2b6 158 Pfam PF12867 DinB superfamily 11 142 5.1E-12 T 29-03-2018 IPR024775 DinB-like domain A616_RS28135 d1ff7423ae2edc795e64ccb97ef9e2b6 158 Gene3D G3DSA:1.20.120.450 1 151 1.2E-17 T 29-03-2018 A616_RS28135 d1ff7423ae2edc795e64ccb97ef9e2b6 158 SUPERFAMILY SSF109854 1 157 8.39E-31 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 Pfam PF08281 Sigma-70, region 4 131 183 1.5E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 SUPERFAMILY SSF88946 17 118 2.59E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 186 1.8E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 Gene3D G3DSA:1.10.1740.10 12 133 2.6E-21 T 29-03-2018 A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 Pfam PF04542 Sigma-70 region 2 38 105 5.3E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 Gene3D G3DSA:1.10.10.10 134 190 7.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12015 c2d875b3ea753ebf5f6133cbef88788d 191 SUPERFAMILY SSF88659 126 187 6.54E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS08980 a2f22bdfd741db4df774400299e96454 187 Gene3D G3DSA:3.40.30.10 3 185 8.9E-15 T 29-03-2018 A616_RS08980 a2f22bdfd741db4df774400299e96454 187 Pfam PF14595 Thioredoxin 13 140 3.7E-41 T 29-03-2018 A616_RS08980 a2f22bdfd741db4df774400299e96454 187 SUPERFAMILY SSF52833 57 133 2.41E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS29335 cfce31ff18ebe1b29094f2cff69fa5e3 445 SUPERFAMILY SSF109604 234 418 4.94E-42 T 29-03-2018 A616_RS29335 cfce31ff18ebe1b29094f2cff69fa5e3 445 SMART SM00471 253 388 5.5E-16 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS29335 cfce31ff18ebe1b29094f2cff69fa5e3 445 Pfam PF01966 HD domain 259 379 1.5E-23 T 29-03-2018 IPR006674 HD domain A616_RS29335 cfce31ff18ebe1b29094f2cff69fa5e3 445 Gene3D G3DSA:1.10.3210.10 198 425 2.5E-55 T 29-03-2018 A616_RS29335 cfce31ff18ebe1b29094f2cff69fa5e3 445 TIGRFAM TIGR00277 HDIG: HDIG domain 259 347 9.8E-9 T 29-03-2018 IPR006675 HDIG domain A616_RS29835 1ff445343ee336614650c5b3ab6bb793 510 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 9 488 17.47 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A616_RS29835 1ff445343ee336614650c5b3ab6bb793 510 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 12 487 2.5E-117 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 A616_RS29835 1ff445343ee336614650c5b3ab6bb793 510 Pfam PF00361 Proton-conducting membrane transporter 132 438 2.1E-68 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS32295 e58f250b708dc42f22242a65dac6bad4 252 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 241 28.88 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes A616_RS32295 e58f250b708dc42f22242a65dac6bad4 252 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 59 238 5.3E-67 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A616_RS32295 e58f250b708dc42f22242a65dac6bad4 252 Pfam PF02096 60Kd inner membrane protein 60 238 2.9E-60 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A616_RS15745 4e501551a08d8e6907b5394f94ffbcf4 473 Gene3D G3DSA:3.40.710.10 2 372 5.9E-86 T 29-03-2018 A616_RS15745 4e501551a08d8e6907b5394f94ffbcf4 473 SUPERFAMILY SSF56601 4 362 1.14E-87 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS15745 4e501551a08d8e6907b5394f94ffbcf4 473 Pfam PF00144 Beta-lactamase 10 356 1.3E-70 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 SUPERFAMILY SSF51735 6 255 1.7E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 Gene3D G3DSA:3.40.50.720 1 256 2.9E-47 T 29-03-2018 A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 1.0E-86 T 29-03-2018 A616_RS22230 c6ec031dd34b8f601231a87f15104fe5 257 PIRSF PIRSF000094 2 257 4.3E-106 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A616_RS12860 827f49d58efafd811bbbeb8f311ec84b 114 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 2.0E-25 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 A616_RS12860 827f49d58efafd811bbbeb8f311ec84b 114 PIRSF PIRSF031653 1 94 8.4E-26 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 SUPERFAMILY SSF103473 4 385 2.35E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 Pfam PF07690 Major Facilitator Superfamily 211 378 1.4E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 Pfam PF07690 Major Facilitator Superfamily 11 192 2.7E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 Gene3D G3DSA:1.20.1250.20 196 389 3.1E-24 T 29-03-2018 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 Gene3D G3DSA:1.20.1250.20 3 192 9.6E-35 T 29-03-2018 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 PRINTS PR01035 Tetracycline resistance protein signature 46 65 2.6E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 PRINTS PR01035 Tetracycline resistance protein signature 299 319 2.6E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 PRINTS PR01035 Tetracycline resistance protein signature 131 153 2.6E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS18790 507f385d60f3b7b89a1c0ab47b66a55b 394 PRINTS PR01035 Tetracycline resistance protein signature 16 32 2.6E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 PIRSF PIRSF000303 1 157 1.2E-67 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 PRINTS PR01011 Glutathione peroxidase family signature 56 72 2.3E-20 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 PRINTS PR01011 Glutathione peroxidase family signature 21 38 2.3E-20 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 PRINTS PR01011 Glutathione peroxidase family signature 121 130 2.3E-20 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 SUPERFAMILY SSF52833 1 157 5.33E-62 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 Gene3D G3DSA:3.40.30.10 1 157 1.2E-51 T 29-03-2018 A616_RS21525 853be81c81a333a8517d9a86ca77e8b4 157 Pfam PF00255 Glutathione peroxidase 3 110 1.9E-45 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 A616_RS24030 1350d817b97520b2ebeab47484ea7ff6 433 Pfam PF07690 Major Facilitator Superfamily 15 257 8.5E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24030 1350d817b97520b2ebeab47484ea7ff6 433 Pfam PF07690 Major Facilitator Superfamily 284 409 5.1E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24030 1350d817b97520b2ebeab47484ea7ff6 433 SUPERFAMILY SSF103473 13 419 3.92E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS24030 1350d817b97520b2ebeab47484ea7ff6 433 Gene3D G3DSA:1.20.1250.20 3 213 2.4E-25 T 29-03-2018 A616_RS24030 1350d817b97520b2ebeab47484ea7ff6 433 Gene3D G3DSA:1.20.1250.20 215 427 2.3E-18 T 29-03-2018 A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 Gene3D G3DSA:1.10.357.10 62 195 8.6E-20 T 29-03-2018 A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 SUPERFAMILY SSF46689 3 87 1.9E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 Gene3D G3DSA:1.10.10.60 1 61 5.0E-16 T 29-03-2018 A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 SUPERFAMILY SSF48498 81 193 6.82E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 9.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS24395 d2ffe5bcc3e0ad4a8063f52c2011d19a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 9.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS00490 dcaa577e8140a5d0a750d04a85c59727 296 Pfam PF00892 EamA-like transporter family 2 132 9.3E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS00490 dcaa577e8140a5d0a750d04a85c59727 296 Pfam PF00892 EamA-like transporter family 148 280 3.1E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS00490 dcaa577e8140a5d0a750d04a85c59727 296 SUPERFAMILY SSF103481 40 132 3.07E-6 T 29-03-2018 A616_RS00490 dcaa577e8140a5d0a750d04a85c59727 296 SUPERFAMILY SSF103481 188 283 2.62E-12 T 29-03-2018 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 Gene3D G3DSA:1.10.1140.10 356 466 2.5E-43 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 2.3E-24 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 137 350 5.3E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 SUPERFAMILY SSF52540 84 353 1.31E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 SUPERFAMILY SSF50615 2 81 2.49E-28 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 SMART SM00382 149 389 3.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 Gene3D G3DSA:3.40.50.300 83 355 1.2E-91 T 29-03-2018 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 468 58.199 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 468 1.7E-257 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 Gene3D G3DSA:2.40.10.170 1 82 1.2E-31 T 29-03-2018 A616_RS29900 93dee8e5fab1ba481174bff1b14bca51 469 SUPERFAMILY SSF47917 353 468 3.66E-52 T 29-03-2018 A616_RS23510 e4f80dc2a25fdcb7d8d4e4a49bbd8d7f 297 SUPERFAMILY SSF53474 24 294 1.58E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS23510 e4f80dc2a25fdcb7d8d4e4a49bbd8d7f 297 Gene3D G3DSA:3.40.50.1820 2 297 1.7E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS23510 e4f80dc2a25fdcb7d8d4e4a49bbd8d7f 297 Pfam PF07859 alpha/beta hydrolase fold 61 270 7.5E-71 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 SMART SM00788 3 422 1.6E-290 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 SUPERFAMILY SSF52540 1 426 1.17E-175 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 Pfam PF00709 Adenylosuccinate synthetase 4 421 6.7E-185 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 210.441 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 Gene3D G3DSA:3.90.170.10 265 428 5.7E-69 T 29-03-2018 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 Gene3D G3DSA:3.40.440.10 1 149 8.4E-54 T 29-03-2018 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 Gene3D G3DSA:3.40.440.10 150 264 5.5E-28 T 29-03-2018 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A616_RS32150 f2f967510627dbfa84829fbfad8e668e 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 1.3E-191 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A616_RS01245 80c96ca328e3a33a25ddd609eff4b2e4 242 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 168 1.8E-44 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 A616_RS01245 80c96ca328e3a33a25ddd609eff4b2e4 242 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 71 1.0E-15 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS01245 80c96ca328e3a33a25ddd609eff4b2e4 242 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 Pfam PF01494 FAD binding domain 7 345 5.2E-27 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 SUPERFAMILY SSF51905 5 170 2.59E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 SUPERFAMILY SSF51905 268 374 2.59E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 1.4E-21 T 29-03-2018 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 1.4E-21 T 29-03-2018 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 1.4E-21 T 29-03-2018 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.4E-21 T 29-03-2018 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.4E-21 T 29-03-2018 A616_RS09965 b4d81912940a732c2fe716a5359d9ede 389 Gene3D G3DSA:3.50.50.60 4 352 8.5E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS20045 3e482146a0422e7305bf688d2d12cc53 98 Pfam PF02049 Flagellar hook-basal body complex protein FliE 18 98 6.9E-29 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A616_RS20045 3e482146a0422e7305bf688d2d12cc53 98 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 83 96 1.4E-13 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A616_RS20045 3e482146a0422e7305bf688d2d12cc53 98 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 28 44 1.4E-13 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A616_RS20045 3e482146a0422e7305bf688d2d12cc53 98 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 62 78 1.4E-13 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A616_RS20045 3e482146a0422e7305bf688d2d12cc53 98 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 6 98 3.8E-23 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A616_RS20045 3e482146a0422e7305bf688d2d12cc53 98 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 98 16.986 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A616_RS03675 7dca8b0c871cc255242233e16c7d9e68 372 Gene3D G3DSA:3.40.190.10 170 327 3.2E-34 T 29-03-2018 A616_RS03675 7dca8b0c871cc255242233e16c7d9e68 372 SUPERFAMILY SSF53850 49 364 4.46E-55 T 29-03-2018 A616_RS03675 7dca8b0c871cc255242233e16c7d9e68 372 Gene3D G3DSA:3.40.190.10 33 169 4.7E-18 T 29-03-2018 A616_RS03675 7dca8b0c871cc255242233e16c7d9e68 372 Pfam PF13416 Bacterial extracellular solute-binding protein 69 334 1.2E-31 T 29-03-2018 A616_RS05765 ca07f9eaf84c45fa57947bd08462444d 264 Gene3D G3DSA:3.40.830.10 1 261 7.4E-83 T 29-03-2018 A616_RS05765 ca07f9eaf84c45fa57947bd08462444d 264 PIRSF PIRSF006157 1 262 1.0E-88 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 A616_RS05765 ca07f9eaf84c45fa57947bd08462444d 264 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 260 6.1E-47 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A616_RS05765 ca07f9eaf84c45fa57947bd08462444d 264 SUPERFAMILY SSF53213 1 261 4.71E-88 T 29-03-2018 A616_RS12615 b6c41dfa634212e53a9ec52c98fe4fc3 222 Gene3D G3DSA:1.20.144.10 48 213 2.4E-24 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS12615 b6c41dfa634212e53a9ec52c98fe4fc3 222 Pfam PF01569 PAP2 superfamily 88 202 1.0E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS12615 b6c41dfa634212e53a9ec52c98fe4fc3 222 SUPERFAMILY SSF48317 15 205 5.89E-37 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS12615 b6c41dfa634212e53a9ec52c98fe4fc3 222 SMART SM00014 88 201 8.2E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 SUPERFAMILY SSF52540 4 252 1.59E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 SMART SM00382 33 239 2.3E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 1.5E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 Pfam PF00005 ABC transporter 25 181 5.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 295 6.6E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS16035 bafb1208c673b1d612f6136f1d284b5f 331 Gene3D G3DSA:3.40.50.300 1 330 5.3E-80 T 29-03-2018 A616_RS07265 522ed084a092987c8653745338703f21 286 Pfam PF00899 ThiF family 16 274 5.1E-45 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS07265 522ed084a092987c8653745338703f21 286 SUPERFAMILY SSF69572 3 273 7.85E-55 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS07265 522ed084a092987c8653745338703f21 286 Gene3D G3DSA:3.40.50.720 5 279 1.6E-48 T 29-03-2018 A616_RS19100 25bb77bdf86de0027716c3728a54b051 345 Pfam PF00704 Glycosyl hydrolases family 18 99 331 8.0E-34 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A616_RS19100 25bb77bdf86de0027716c3728a54b051 345 SMART SM00636 32 332 4.9E-26 T 29-03-2018 IPR011583 Chitinase II GO:0008061 A616_RS19100 25bb77bdf86de0027716c3728a54b051 345 Gene3D G3DSA:3.20.20.80 24 345 1.3E-46 T 29-03-2018 A616_RS19100 25bb77bdf86de0027716c3728a54b051 345 SUPERFAMILY SSF51445 33 245 1.74E-41 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS19100 25bb77bdf86de0027716c3728a54b051 345 SUPERFAMILY SSF51445 304 339 1.74E-41 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily A616_RS14370 60629054138e403a00ea4198e9c89e1f 208 SUPERFAMILY SSF56529 4 196 2.88E-52 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS14370 60629054138e403a00ea4198e9c89e1f 208 Gene3D G3DSA:3.90.850.10 1 208 5.2E-55 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS14370 60629054138e403a00ea4198e9c89e1f 208 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 6 203 2.2E-36 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS12555 67d2a817077f0e3d3fe2d69b4b83d584 128 Gene3D G3DSA:3.10.180.10 1 128 5.7E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS12555 67d2a817077f0e3d3fe2d69b4b83d584 128 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 114 8.6E-9 T 29-03-2018 A616_RS12555 67d2a817077f0e3d3fe2d69b4b83d584 128 SUPERFAMILY SSF54593 2 128 1.65E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS13885 5448e45766ee76c79d06c63798b8d09d 172 Gene3D G3DSA:2.102.10.10 49 160 2.8E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS13885 5448e45766ee76c79d06c63798b8d09d 172 SUPERFAMILY SSF50022 6 159 1.96E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS13885 5448e45766ee76c79d06c63798b8d09d 172 Gene3D G3DSA:1.20.5.700 1 39 3.1E-15 T 29-03-2018 A616_RS13885 5448e45766ee76c79d06c63798b8d09d 172 Pfam PF00355 Rieske [2Fe-2S] domain 73 148 1.5E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 374 388 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 171 179 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 218 233 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 502 515 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 280 293 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 294 307 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 440 451 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 204 217 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 PRINTS PR00415 Aconitase family signature 147 160 1.6E-43 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 Gene3D G3DSA:3.30.499.10 374 585 7.6E-66 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 Gene3D G3DSA:3.20.19.10 662 902 2.8E-90 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 Gene3D G3DSA:3.40.1060.10 241 373 1.8E-45 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 Pfam PF00330 Aconitase family (aconitate hydratase) 72 571 2.6E-180 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 Gene3D G3DSA:3.30.499.10 36 240 9.2E-74 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 SUPERFAMILY SSF52016 640 901 3.53E-84 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 Pfam PF00694 Aconitase C-terminal domain 701 827 8.2E-47 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 901 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A616_RS23140 08fab67ef9681128b48ded7c29c51001 909 SUPERFAMILY SSF53732 6 636 1.05E-224 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A616_RS14440 c3fb332649565be9bc2affd1c50eb201 297 Gene3D G3DSA:1.20.1260.10 1 198 1.2E-47 T 29-03-2018 IPR012347 Ferritin-related A616_RS14440 c3fb332649565be9bc2affd1c50eb201 297 SUPERFAMILY SSF47240 2 291 2.14E-88 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS14440 c3fb332649565be9bc2affd1c50eb201 297 Pfam PF05067 Manganese containing catalase 4 295 1.0E-85 T 29-03-2018 IPR007760 Manganese catalase A616_RS10090 f8b0560b82f128fcc34d7c5bcc1dd94c 295 SUPERFAMILY SSF51735 1 294 3.42E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10090 f8b0560b82f128fcc34d7c5bcc1dd94c 295 Gene3D G3DSA:3.90.25.10 172 295 1.7E-24 T 29-03-2018 A616_RS10090 f8b0560b82f128fcc34d7c5bcc1dd94c 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 218 2.7E-35 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS10090 f8b0560b82f128fcc34d7c5bcc1dd94c 295 Gene3D G3DSA:3.40.50.720 1 171 1.0E-21 T 29-03-2018 A616_RS16180 e439cd18c19c2fa7a469e545590a7860 157 Pfam PF14270 Domain of unknown function (DUF4358) 43 142 1.1E-27 T 29-03-2018 IPR025648 Protein of unknown function DUF4358 A616_RS16180 e439cd18c19c2fa7a469e545590a7860 157 Gene3D G3DSA:3.40.190.10 1 148 1.8E-6 T 29-03-2018 A616_RS07890 cca9460dfc9784a71f2214c3b52a811d 385 Pfam PF04286 Protein of unknown function (DUF445) 11 383 5.9E-65 T 29-03-2018 IPR007383 Protein of unknown function DUF445 A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 SUPERFAMILY SSF88659 98 158 2.8E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 Gene3D G3DSA:1.10.10.10 78 164 2.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 SUPERFAMILY SSF88946 11 90 5.1E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 Pfam PF04542 Sigma-70 region 2 12 79 2.3E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 Pfam PF08281 Sigma-70, region 4 104 154 9.4E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 157 4.4E-21 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS09015 37af68cb766d8d7ce9ec0a02bcb0580a 167 Gene3D G3DSA:1.10.1740.10 3 77 1.9E-14 T 29-03-2018 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 Gene3D G3DSA:1.10.10.10 123 147 0.11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 Gene3D G3DSA:1.10.10.10 8 122 3.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 2.2E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 Pfam PF01047 MarR family 37 94 1.1E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 SMART SM00347 30 130 1.0E-29 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS02200 6d0c473ac111cc1bf6ee653fb851dd8e 148 SUPERFAMILY SSF46785 10 144 4.48E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27435 90449df8554758028f1c4e03109a03d8 110 Pfam PF06243 Phenylacetic acid degradation B 6 91 5.5E-26 T 29-03-2018 IPR009359 Phenylacetic acid degradation B A616_RS27435 90449df8554758028f1c4e03109a03d8 110 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 8 93 8.5E-27 T 29-03-2018 IPR009359 Phenylacetic acid degradation B A616_RS27435 90449df8554758028f1c4e03109a03d8 110 PIRSF PIRSF030200 1 104 2.8E-25 T 29-03-2018 IPR009359 Phenylacetic acid degradation B A616_RS08310 534f50ce2b045ef8cecdc63eae95c592 371 Pfam PF00144 Beta-lactamase 49 341 1.5E-42 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS08310 534f50ce2b045ef8cecdc63eae95c592 371 SUPERFAMILY SSF56601 27 356 7.66E-60 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS08310 534f50ce2b045ef8cecdc63eae95c592 371 Gene3D G3DSA:3.40.710.10 4 364 7.1E-61 T 29-03-2018 A616_RS06640 d71ec852619b8428655cad8043b564bf 86 Pfam PF10676 Spore germination protein gerPA/gerPF 2 58 5.1E-13 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF A616_RS13465 f92946bc39bf51571322c1b8ba89622a 222 Pfam PF02163 Peptidase family M50 124 165 1.5E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A616_RS05725 e8232bdf23f2b6c0524948659717dd19 260 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 175 5.0E-23 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS05725 e8232bdf23f2b6c0524948659717dd19 260 SUPERFAMILY SSF53187 4 181 1.26E-26 T 29-03-2018 A616_RS05725 e8232bdf23f2b6c0524948659717dd19 260 Gene3D G3DSA:3.40.630.40 2 184 1.5E-32 T 29-03-2018 A616_RS05725 e8232bdf23f2b6c0524948659717dd19 260 SMART SM00646 64 176 4.3E-4 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS19250 d015d66f927fbfd9074256bf48d203a2 191 SUPERFAMILY SSF46689 2 64 8.72E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS19250 d015d66f927fbfd9074256bf48d203a2 191 SUPERFAMILY SSF48498 78 191 8.16E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS19250 d015d66f927fbfd9074256bf48d203a2 191 Gene3D G3DSA:1.10.10.60 1 57 8.2E-12 T 29-03-2018 A616_RS19250 d015d66f927fbfd9074256bf48d203a2 191 Gene3D G3DSA:1.10.357.10 58 191 4.8E-15 T 29-03-2018 A616_RS19250 d015d66f927fbfd9074256bf48d203a2 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 3.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS21210 5f5f00a297e7533df3f52b1284946898 257 Pfam PF01479 S4 domain 194 227 6.1E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS21210 5f5f00a297e7533df3f52b1284946898 257 SMART SM00363 181 241 1.3E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS21210 5f5f00a297e7533df3f52b1284946898 257 Gene3D G3DSA:3.10.290.10 180 233 5.1E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A616_RS21210 5f5f00a297e7533df3f52b1284946898 257 SUPERFAMILY SSF55174 178 256 5.5E-30 T 29-03-2018 A616_RS21210 5f5f00a297e7533df3f52b1284946898 257 SUPERFAMILY SSF55174 35 126 5.5E-30 T 29-03-2018 A616_RS31725 a4cefdb2b0235e9521c77aa044d6a962 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 8.5E-34 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS31725 a4cefdb2b0235e9521c77aa044d6a962 217 SUPERFAMILY SSF161098 14 201 1.83E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31725 a4cefdb2b0235e9521c77aa044d6a962 217 Gene3D G3DSA:1.10.3720.10 2 217 2.9E-53 T 29-03-2018 A616_RS31725 a4cefdb2b0235e9521c77aa044d6a962 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 216 2.1E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS17710 a8d350d4cab5fe0aaefc485b483d2f6b 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 154 7.4E-15 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A616_RS17710 a8d350d4cab5fe0aaefc485b483d2f6b 164 Gene3D G3DSA:3.10.50.30 76 156 4.3E-16 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A616_RS17710 a8d350d4cab5fe0aaefc485b483d2f6b 164 SUPERFAMILY SSF54534 85 154 2.62E-12 T 29-03-2018 A616_RS20805 58c26c16689641a86388084813e45de2 206 Gene3D G3DSA:3.40.50.300 2 52 1.6E-9 T 29-03-2018 A616_RS20805 58c26c16689641a86388084813e45de2 206 Hamap MF_00328 Guanylate kinase [gmk]. 5 188 37.395 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A616_RS20805 58c26c16689641a86388084813e45de2 206 SMART SM00072 6 188 3.9E-67 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A616_RS20805 58c26c16689641a86388084813e45de2 206 Pfam PF00625 Guanylate kinase 9 186 4.2E-47 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A616_RS20805 58c26c16689641a86388084813e45de2 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 8 185 1.6E-72 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A616_RS20805 58c26c16689641a86388084813e45de2 206 Gene3D G3DSA:3.40.50.300 85 188 7.9E-31 T 29-03-2018 A616_RS20805 58c26c16689641a86388084813e45de2 206 SUPERFAMILY SSF52540 6 190 2.04E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20805 58c26c16689641a86388084813e45de2 206 Gene3D G3DSA:3.30.63.10 53 84 2.7E-25 T 29-03-2018 A616_RS20805 58c26c16689641a86388084813e45de2 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A616_RS08245 8c3e440de91a9391d0caa4b796fd2656 220 SUPERFAMILY SSF56436 106 219 7.53E-51 T 29-03-2018 IPR016187 C-type lectin fold A616_RS08245 8c3e440de91a9391d0caa4b796fd2656 220 SUPERFAMILY SSF56436 5 79 7.53E-51 T 29-03-2018 IPR016187 C-type lectin fold A616_RS08245 8c3e440de91a9391d0caa4b796fd2656 220 Pfam PF03781 Sulfatase-modifying factor enzyme 1 7 218 8.8E-39 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 A616_RS08245 8c3e440de91a9391d0caa4b796fd2656 220 Gene3D G3DSA:3.90.1580.10 25 215 2.1E-46 T 29-03-2018 A616_RS29315 86c340b0a42d3ccbaa7a0c27765847a0 303 Pfam PF03069 Acetamidase/Formamidase family 15 142 1.8E-14 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A616_RS29315 86c340b0a42d3ccbaa7a0c27765847a0 303 Pfam PF03069 Acetamidase/Formamidase family 140 277 1.2E-22 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 A616_RS29315 86c340b0a42d3ccbaa7a0c27765847a0 303 Gene3D G3DSA:2.60.120.580 1 211 1.8E-54 T 29-03-2018 A616_RS29315 86c340b0a42d3ccbaa7a0c27765847a0 303 SUPERFAMILY SSF141130 3 289 2.62E-88 T 29-03-2018 A616_RS29315 86c340b0a42d3ccbaa7a0c27765847a0 303 Gene3D G3DSA:3.10.28.20 215 291 2.3E-22 T 29-03-2018 A616_RS29710 a5121bdee296ac82cf41b79f51fc4e22 365 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 361 1.0E-117 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 A616_RS29710 a5121bdee296ac82cf41b79f51fc4e22 365 Gene3D G3DSA:3.40.50.2000 208 337 1.0E-23 T 29-03-2018 A616_RS29710 a5121bdee296ac82cf41b79f51fc4e22 365 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 361 1.0E-101 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A616_RS29710 a5121bdee296ac82cf41b79f51fc4e22 365 Gene3D G3DSA:3.40.50.2000 1 207 7.1E-88 T 29-03-2018 A616_RS29710 a5121bdee296ac82cf41b79f51fc4e22 365 SUPERFAMILY SSF53756 1 362 6.28E-108 T 29-03-2018 A616_RS27820 4cb65588af8b9285e9fa40e04701b696 384 SUPERFAMILY SSF53649 3 365 1.48E-43 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS27820 4cb65588af8b9285e9fa40e04701b696 384 Gene3D G3DSA:3.40.720.10 2 384 1.3E-27 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS27820 4cb65588af8b9285e9fa40e04701b696 384 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 3 240 1.6E-28 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A616_RS08560 eb954b3096d7031f79baf8720a8b287e 286 Pfam PF00950 ABC 3 transport family 9 264 1.8E-83 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A616_RS08560 eb954b3096d7031f79baf8720a8b287e 286 SUPERFAMILY SSF81345 5 260 4.45E-42 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS08560 eb954b3096d7031f79baf8720a8b287e 286 Gene3D G3DSA:1.10.3470.10 7 272 5.5E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS09940 4fb80ad5d3e84e95a18ebffe6b74a864 274 Pfam PF01261 Xylose isomerase-like TIM barrel 22 215 4.5E-39 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS09940 4fb80ad5d3e84e95a18ebffe6b74a864 274 Gene3D G3DSA:3.20.20.150 1 274 5.4E-58 T 29-03-2018 A616_RS09940 4fb80ad5d3e84e95a18ebffe6b74a864 274 SUPERFAMILY SSF51658 3 260 9.69E-54 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS11575 662d39f1d52d34492ea21fa3866b965e 376 SUPERFAMILY SSF82171 196 353 1.28E-12 T 29-03-2018 A616_RS11575 662d39f1d52d34492ea21fa3866b965e 376 SUPERFAMILY SSF82171 48 161 1.28E-12 T 29-03-2018 A616_RS11575 662d39f1d52d34492ea21fa3866b965e 376 Gene3D G3DSA:2.140.10.30 29 95 3.1E-4 T 29-03-2018 A616_RS11575 662d39f1d52d34492ea21fa3866b965e 376 Gene3D G3DSA:2.140.10.30 96 373 5.0E-10 T 29-03-2018 A616_RS13370 bbd66081a3d2c7d1f7c97dd7e36adad4 310 SUPERFAMILY SSF161098 88 286 6.98E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS13370 bbd66081a3d2c7d1f7c97dd7e36adad4 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 6.0E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS13370 bbd66081a3d2c7d1f7c97dd7e36adad4 310 Gene3D G3DSA:1.10.3720.10 3 292 3.1E-37 T 29-03-2018 A616_RS18385 72a490c57ca86c37e6aa78c07cd00cc3 175 Pfam PF00857 Isochorismatase family 3 156 2.1E-33 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS18385 72a490c57ca86c37e6aa78c07cd00cc3 175 SUPERFAMILY SSF52499 3 164 2.09E-39 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS18385 72a490c57ca86c37e6aa78c07cd00cc3 175 Gene3D G3DSA:3.40.50.850 1 173 2.4E-34 T 29-03-2018 A616_RS28085 b49460a88c5741cac5b3d7340a4641b1 734 Gene3D G3DSA:1.20.1250.20 376 643 0.0014 T 29-03-2018 A616_RS14400 62fcd0d3fdddb1a652e98dd8431e7900 395 SUPERFAMILY SSF53822 28 390 2.3E-79 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS14400 62fcd0d3fdddb1a652e98dd8431e7900 395 Gene3D G3DSA:3.40.50.2300 12 195 5.1E-38 T 29-03-2018 A616_RS14400 62fcd0d3fdddb1a652e98dd8431e7900 395 Pfam PF13458 Periplasmic binding protein 28 366 2.6E-71 T 29-03-2018 IPR028081 Leucine-binding protein domain A616_RS14400 62fcd0d3fdddb1a652e98dd8431e7900 395 Gene3D G3DSA:3.40.50.2300 196 361 6.3E-18 T 29-03-2018 A616_RS27240 39f586127a208698f6b0fa1658dc14b1 128 SUPERFAMILY SSF52821 25 127 8.12E-22 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS27240 39f586127a208698f6b0fa1658dc14b1 128 Gene3D G3DSA:3.40.250.10 10 128 1.6E-21 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS27240 39f586127a208698f6b0fa1658dc14b1 128 ProSitePatterns PS00380 Rhodanese signature 1. 54 65 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A616_RS27240 39f586127a208698f6b0fa1658dc14b1 128 Pfam PF00581 Rhodanese-like domain 41 122 6.3E-11 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS27240 39f586127a208698f6b0fa1658dc14b1 128 SMART SM00450 29 126 1.2E-12 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS02300 c3c08161495b87db7e043ef70567d7e7 280 Pfam PF00491 Arginase family 2 274 7.0E-28 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS02300 c3c08161495b87db7e043ef70567d7e7 280 PIRSF PIRSF036979 148 279 3.8E-4 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS02300 c3c08161495b87db7e043ef70567d7e7 280 PIRSF PIRSF036979 1 128 2.0E-5 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS02300 c3c08161495b87db7e043ef70567d7e7 280 Gene3D G3DSA:3.40.800.10 1 279 8.3E-41 T 29-03-2018 A616_RS02300 c3c08161495b87db7e043ef70567d7e7 280 SUPERFAMILY SSF52768 2 278 3.06E-39 T 29-03-2018 A616_RS09125 579b3e5e97e50d19c797ff97d9416130 439 SUPERFAMILY SSF53850 22 434 1.3E-83 T 29-03-2018 A616_RS09125 579b3e5e97e50d19c797ff97d9416130 439 Gene3D G3DSA:3.40.190.10 247 386 4.9E-19 T 29-03-2018 A616_RS09125 579b3e5e97e50d19c797ff97d9416130 439 Pfam PF13416 Bacterial extracellular solute-binding protein 61 371 2.3E-41 T 29-03-2018 A616_RS09125 579b3e5e97e50d19c797ff97d9416130 439 Gene3D G3DSA:3.40.190.10 40 246 4.1E-38 T 29-03-2018 A616_RS05845 292b81a971e037279d2ca945fea35314 409 Gene3D G3DSA:1.20.1250.20 1 204 3.6E-9 T 29-03-2018 A616_RS05845 292b81a971e037279d2ca945fea35314 409 Pfam PF07690 Major Facilitator Superfamily 11 338 9.0E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05845 292b81a971e037279d2ca945fea35314 409 Gene3D G3DSA:1.20.1250.20 205 401 2.2E-16 T 29-03-2018 A616_RS05845 292b81a971e037279d2ca945fea35314 409 SUPERFAMILY SSF103473 4 399 8.46E-28 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS04945 c0a9cbf9a877ee8336b8ff631f2a34cc 308 SUPERFAMILY SSF103481 195 292 2.09E-16 T 29-03-2018 A616_RS04945 c0a9cbf9a877ee8336b8ff631f2a34cc 308 SUPERFAMILY SSF103481 43 145 2.22E-19 T 29-03-2018 A616_RS04945 c0a9cbf9a877ee8336b8ff631f2a34cc 308 Pfam PF00892 EamA-like transporter family 10 143 1.1E-30 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS04945 c0a9cbf9a877ee8336b8ff631f2a34cc 308 Pfam PF00892 EamA-like transporter family 157 290 3.1E-29 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS20150 139886501ccf89ac92ba82345c300b49 514 Gene3D G3DSA:3.40.50.300 182 434 3.9E-23 T 29-03-2018 A616_RS20150 139886501ccf89ac92ba82345c300b49 514 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 506 1.9E-174 T 29-03-2018 IPR004482 Mg chelatase-related protein A616_RS20150 139886501ccf89ac92ba82345c300b49 514 SUPERFAMILY SSF54211 7 165 7.21E-37 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A616_RS20150 139886501ccf89ac92ba82345c300b49 514 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 141 2.0E-45 T 29-03-2018 A616_RS20150 139886501ccf89ac92ba82345c300b49 514 SMART SM00382 214 399 6.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS20150 139886501ccf89ac92ba82345c300b49 514 SUPERFAMILY SSF52540 192 508 7.0E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS20150 139886501ccf89ac92ba82345c300b49 514 Pfam PF01078 Magnesium chelatase, subunit ChlI 194 400 1.2E-86 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain A616_RS20150 139886501ccf89ac92ba82345c300b49 514 Gene3D G3DSA:3.30.230.10 3 181 8.5E-44 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A616_RS20150 139886501ccf89ac92ba82345c300b49 514 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 410 506 4.2E-32 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain A616_RS13205 0c5e431b9ffa8d7446cb6a31a5b51aef 293 SUPERFAMILY SSF56300 67 292 2.13E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS13205 0c5e431b9ffa8d7446cb6a31a5b51aef 293 Gene3D G3DSA:3.60.21.10 68 293 1.5E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS13205 0c5e431b9ffa8d7446cb6a31a5b51aef 293 Pfam PF00149 Calcineurin-like phosphoesterase 72 233 1.5E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A616_RS26080 709c6143a95d7842328cfaf253321b1d 199 SUPERFAMILY SSF48317 5 174 4.06E-33 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS26080 709c6143a95d7842328cfaf253321b1d 199 Pfam PF01569 PAP2 superfamily 90 172 6.3E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS26080 709c6143a95d7842328cfaf253321b1d 199 Gene3D G3DSA:1.20.144.10 16 172 3.0E-19 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS26080 709c6143a95d7842328cfaf253321b1d 199 SMART SM00014 58 166 2.3E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A616_RS20675 8d25d62d84a29af6836c1b6df7c8f8f0 294 Pfam PF03313 Serine dehydratase alpha chain 15 275 4.7E-76 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit A616_RS20675 8d25d62d84a29af6836c1b6df7c8f8f0 294 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 289 8.0E-124 T 29-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A616_RS20675 8d25d62d84a29af6836c1b6df7c8f8f0 294 Gene3D G3DSA:1.10.4100.10 14 276 7.5E-32 T 29-03-2018 A616_RS12175 fcb2ee67162264325f4ddfdd0baa0898 406 Gene3D G3DSA:3.20.20.140 74 344 5.5E-37 T 29-03-2018 A616_RS12175 fcb2ee67162264325f4ddfdd0baa0898 406 SUPERFAMILY SSF51556 60 365 9.61E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS12175 fcb2ee67162264325f4ddfdd0baa0898 406 Gene3D G3DSA:2.30.40.10 345 404 2.9E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS12175 fcb2ee67162264325f4ddfdd0baa0898 406 Gene3D G3DSA:2.30.40.10 2 73 7.3E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS12175 fcb2ee67162264325f4ddfdd0baa0898 406 Pfam PF01979 Amidohydrolase family 57 402 2.5E-35 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS12175 fcb2ee67162264325f4ddfdd0baa0898 406 SUPERFAMILY SSF51338 3 71 9.4E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS19545 61b3dcf77d33808d9a3f887311c4d0aa 415 Pfam PF00395 S-layer homology domain 28 71 1.0E-17 T 29-03-2018 IPR001119 S-layer homology domain A616_RS19545 61b3dcf77d33808d9a3f887311c4d0aa 415 Pfam PF00395 S-layer homology domain 156 199 1.9E-12 T 29-03-2018 IPR001119 S-layer homology domain A616_RS19545 61b3dcf77d33808d9a3f887311c4d0aa 415 Gene3D G3DSA:2.60.120.560 235 412 1.6E-12 T 29-03-2018 A616_RS15475 e748c8443ce170609efc11b2b3c198d2 514 Gene3D G3DSA:2.60.40.1080 59 136 0.0072 T 29-03-2018 A616_RS15475 e748c8443ce170609efc11b2b3c198d2 514 Gene3D G3DSA:1.10.3720.10 226 514 1.0E-43 T 29-03-2018 A616_RS15475 e748c8443ce170609efc11b2b3c198d2 514 SUPERFAMILY SSF161098 307 498 7.72E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15475 e748c8443ce170609efc11b2b3c198d2 514 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 8 54 2.5E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS15475 e748c8443ce170609efc11b2b3c198d2 514 SUPERFAMILY SSF49373 204 250 1.53E-5 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS15475 e748c8443ce170609efc11b2b3c198d2 514 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 330 513 2.4E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS20840 dbb6fa826ecd85557e063b304e42e8e7 141 Gene3D G3DSA:2.60.120.260 16 132 5.0E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS20840 dbb6fa826ecd85557e063b304e42e8e7 141 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 61 129 2.1E-12 T 29-03-2018 IPR018911 Bacterial spore germination, immunoglobulin-like domain A616_RS19575 500fcf7ae0d6a4e2d0a7cca42d93400a 249 SUPERFAMILY SSF56281 1 249 4.59E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19575 500fcf7ae0d6a4e2d0a7cca42d93400a 249 SMART SM00849 18 194 2.0E-6 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19575 500fcf7ae0d6a4e2d0a7cca42d93400a 249 Pfam PF12706 Beta-lactamase superfamily domain 31 216 2.6E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19575 500fcf7ae0d6a4e2d0a7cca42d93400a 249 Gene3D G3DSA:3.60.15.10 1 249 4.8E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS02730 c4d110702d6ca88c6f9986258cb590ac 531 SUPERFAMILY SSF53850 28 524 4.71E-135 T 29-03-2018 A616_RS02730 c4d110702d6ca88c6f9986258cb590ac 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 451 3.6E-87 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS02730 c4d110702d6ca88c6f9986258cb590ac 531 Gene3D G3DSA:3.10.105.10 305 501 5.8E-55 T 29-03-2018 A616_RS02730 c4d110702d6ca88c6f9986258cb590ac 531 Gene3D G3DSA:3.40.190.10 166 304 1.8E-40 T 29-03-2018 A616_RS02730 c4d110702d6ca88c6f9986258cb590ac 531 Gene3D G3DSA:3.90.76.10 56 165 5.2E-32 T 29-03-2018 A616_RS02730 c4d110702d6ca88c6f9986258cb590ac 531 PIRSF PIRSF002741 6 531 1.1E-129 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 SUPERFAMILY SSF47060 3 89 1.77E-36 T 29-03-2018 IPR009068 S15/NS1, RNA-binding A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 9.0E-33 T 29-03-2018 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 Gene3D G3DSA:1.10.287.10 2 89 3.7E-36 T 29-03-2018 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 SMART SM01387 8 88 1.7E-51 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.4E-41 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 Pfam PF00312 Ribosomal protein S15 8 88 1.1E-37 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.623 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS19770 8e79205b9a7efcdefd26d15b8c355e66 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 Gene3D G3DSA:3.30.565.10 178 414 6.7E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 SMART SM00387 304 415 1.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 413 1.8E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 SUPERFAMILY SSF55874 268 412 6.55E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 369 8.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 355 8.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS07205 719aa9f9e327fe7da1497c4253afc16a 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 8.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A616_RS24745 5daa7118cbf646be3eebdb20b9b8b157 170 Gene3D G3DSA:3.40.630.30 78 170 8.3E-18 T 29-03-2018 A616_RS24745 5daa7118cbf646be3eebdb20b9b8b157 170 SUPERFAMILY SSF55729 82 169 2.34E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS24745 5daa7118cbf646be3eebdb20b9b8b157 170 Pfam PF14542 GCN5-related N-acetyl-transferase 91 168 1.0E-22 T 29-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase A616_RS24745 5daa7118cbf646be3eebdb20b9b8b157 170 Pfam PF06902 Divergent 4Fe-4S mono-cluster 8 69 2.7E-23 T 29-03-2018 IPR010693 Divergent 4Fe-4S mono-cluster A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 SUPERFAMILY SSF56601 194 595 1.61E-92 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 Pfam PF03717 Penicillin-binding Protein dimerisation domain 55 187 1.8E-13 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 Gene3D G3DSA:3.40.710.10 239 594 1.8E-86 T 29-03-2018 A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 584 6.0E-83 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 SUPERFAMILY SSF56519 51 241 3.14E-35 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 Pfam PF03793 PASTA domain 627 680 2.6E-5 T 29-03-2018 IPR005543 PASTA domain A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 SUPERFAMILY SSF54184 624 681 7.06E-10 T 29-03-2018 A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 SMART SM00740 622 681 5.9E-7 T 29-03-2018 IPR005543 PASTA domain A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 SMART SM00740 682 741 3.8E-4 T 29-03-2018 IPR005543 PASTA domain A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 SUPERFAMILY SSF54184 687 740 4.84E-10 T 29-03-2018 A616_RS21325 9ec7efca8e77e986b82d9c2ef693491a 823 Gene3D G3DSA:3.90.1310.10 23 238 2.5E-35 T 29-03-2018 A616_RS12295 ed0cbceb58c37d71e5b16ffa432f9c03 115 SUPERFAMILY SSF103473 20 94 5.75E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS12295 ed0cbceb58c37d71e5b16ffa432f9c03 115 Pfam PF04341 Protein of unknown function, DUF485 25 109 3.5E-25 T 29-03-2018 IPR007436 Protein of unknown function DUF485 A616_RS11630 75aea379d912554d6458c0fd7829de28 323 SUPERFAMILY SSF52540 101 287 9.98E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS11630 75aea379d912554d6458c0fd7829de28 323 Pfam PF02562 PhoH-like protein 112 314 1.6E-97 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 A616_RS11630 75aea379d912554d6458c0fd7829de28 323 Gene3D G3DSA:3.40.50.300 109 315 1.2E-29 T 29-03-2018 A616_RS10140 e9bc8f9836b5f3752965c4120331fe5a 264 SUPERFAMILY SSF53448 3 228 2.94E-52 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10140 e9bc8f9836b5f3752965c4120331fe5a 264 Gene3D G3DSA:3.90.550.10 2 247 2.2E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10140 e9bc8f9836b5f3752965c4120331fe5a 264 Pfam PF00535 Glycosyl transferase family 2 5 144 8.1E-35 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS08440 66b1c463adf80e30f71111a67dccf629 240 Pfam PF02361 Cobalt transport protein 14 200 1.2E-8 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A616_RS24650 0d9982c3aecfb42bd07f4a8186fd7783 351 SUPERFAMILY SSF81345 19 346 4.71E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS24650 0d9982c3aecfb42bd07f4a8186fd7783 351 Pfam PF01032 FecCD transport family 37 346 7.3E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS24650 0d9982c3aecfb42bd07f4a8186fd7783 351 Gene3D G3DSA:1.10.3470.10 21 351 3.0E-65 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS32060 84f47c16972dfaf81eb49c9076358013 125 SUPERFAMILY SSF46785 12 115 5.58E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS32060 84f47c16972dfaf81eb49c9076358013 125 Pfam PF01638 HxlR-like helix-turn-helix 25 111 8.7E-38 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS32060 84f47c16972dfaf81eb49c9076358013 125 Gene3D G3DSA:1.10.10.10 23 118 8.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17950 57d876ccc226169e0954dcc9eb177534 243 Pfam PF12730 ABC-2 family transporter protein 7 182 3.2E-22 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 327 370 2.3E-8 T 29-03-2018 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 39 104 4.2E-11 T 29-03-2018 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 205 269 6.2E-13 T 29-03-2018 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 SUPERFAMILY SSF69318 27 384 1.13E-61 T 29-03-2018 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Gene3D G3DSA:2.60.40.10 457 551 2.9E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Pfam PF02494 HYR domain 416 454 5.1E-7 T 29-03-2018 IPR003410 HYR domain A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Pfam PF02494 HYR domain 457 546 6.9E-10 T 29-03-2018 IPR003410 HYR domain A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Gene3D G3DSA:2.60.40.680 18 58 0.0022 T 29-03-2018 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Gene3D G3DSA:2.60.40.10 390 456 6.7E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Gene3D G3DSA:2.130.10.130 259 387 1.3E-21 T 29-03-2018 A616_RS26185 ec85480e4301020386c49e4f1ea93216 591 Gene3D G3DSA:2.130.10.130 132 258 5.0E-17 T 29-03-2018 A616_RS29060 d3091bdf69287ddf700d49d61a3da628 90 SUPERFAMILY SSF52833 4 85 5.61E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS29060 d3091bdf69287ddf700d49d61a3da628 90 Gene3D G3DSA:3.40.30.10 6 85 1.3E-7 T 29-03-2018 A616_RS29060 d3091bdf69287ddf700d49d61a3da628 90 Pfam PF05768 Glutaredoxin-like domain (DUF836) 8 83 9.9E-13 T 29-03-2018 IPR008554 Glutaredoxin-like A616_RS30030 44184f49f0060639cddcb8cbb02ad425 265 Gene3D G3DSA:3.90.640.20 170 265 4.9E-22 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 A616_RS30030 44184f49f0060639cddcb8cbb02ad425 265 Pfam PF13739 Domain of unknown function (DUF4163) 58 153 3.6E-20 T 29-03-2018 IPR025303 Deacetylase PdaC A616_RS30030 44184f49f0060639cddcb8cbb02ad425 265 Gene3D G3DSA:3.30.565.40 46 167 2.0E-25 T 29-03-2018 A616_RS30030 44184f49f0060639cddcb8cbb02ad425 265 Pfam PF11738 Protein of unknown function (DUF3298) 172 246 2.5E-16 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 256 281 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 388 407 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 222 240 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 291 315 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 201 219 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 162 186 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 1.1E-26 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 SUPERFAMILY SSF103473 9 199 1.7E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 SUPERFAMILY SSF103473 238 454 1.7E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 Gene3D G3DSA:1.20.1250.20 241 459 4.1E-21 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 Gene3D G3DSA:1.20.1250.20 3 190 1.9E-31 T 29-03-2018 A616_RS02545 7b2c42d01a80ee4f4866c526538e8268 459 Pfam PF07690 Major Facilitator Superfamily 17 397 1.1E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24680 d46787c6b030e82d346e391f00f687b3 387 Gene3D G3DSA:3.40.50.720 1 135 1.2E-6 T 29-03-2018 A616_RS24680 d46787c6b030e82d346e391f00f687b3 387 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 125 375 1.2E-17 T 29-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A616_RS24680 d46787c6b030e82d346e391f00f687b3 387 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 101 2.6E-13 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A616_RS24680 d46787c6b030e82d346e391f00f687b3 387 SUPERFAMILY SSF51735 1 142 3.42E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS24680 d46787c6b030e82d346e391f00f687b3 387 Gene3D G3DSA:3.30.360.10 136 319 1.8E-23 T 29-03-2018 A616_RS21205 628e7dd63dc858c93e295378f3f9d11c 163 Pfam PF05103 DivIVA protein 3 133 3.2E-48 T 29-03-2018 IPR007793 DivIVA family A616_RS21205 628e7dd63dc858c93e295378f3f9d11c 163 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 5.9E-17 T 29-03-2018 IPR019933 DivIVA domain A616_RS04950 e755913df3661e89854b84c880a4a7e8 276 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 31 242 7.0E-57 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 A616_RS04950 e755913df3661e89854b84c880a4a7e8 276 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 247 40.009 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 SUPERFAMILY SSF55811 234 365 1.34E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 SMART SM00478 53 204 1.3E-56 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 Pfam PF14815 NUDIX domain 249 363 7.4E-28 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 Gene3D G3DSA:3.90.79.10 240 368 3.5E-22 T 29-03-2018 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 49 180 3.1E-21 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 21 283 2.8E-105 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 Pfam PF00633 Helix-hairpin-helix motif 113 142 1.2E-10 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 Gene3D G3DSA:1.10.340.30 35 131 1.1E-33 T 29-03-2018 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 SUPERFAMILY SSF48150 21 236 1.73E-78 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A616_RS05795 1aff61f5fe2d22ded481a8b2967b1c81 368 Gene3D G3DSA:1.10.1670.10 132 239 5.2E-36 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A616_RS14030 a0a9ceb0416de654a3173b6a8b4325af 390 Gene3D G3DSA:3.40.50.2000 180 358 3.5E-46 T 29-03-2018 A616_RS14030 a0a9ceb0416de654a3173b6a8b4325af 390 Pfam PF00534 Glycosyl transferases group 1 179 352 7.2E-38 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS14030 a0a9ceb0416de654a3173b6a8b4325af 390 Pfam PF13439 Glycosyltransferase Family 4 36 168 3.0E-13 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS14030 a0a9ceb0416de654a3173b6a8b4325af 390 Gene3D G3DSA:3.40.50.2000 6 179 6.5E-8 T 29-03-2018 A616_RS14030 a0a9ceb0416de654a3173b6a8b4325af 390 SUPERFAMILY SSF53756 36 376 1.74E-73 T 29-03-2018 A616_RS29785 d145453abdba4f0058c1d0f965765605 84 Pfam PF11772 DNA-directed RNA polymerase subunit beta 38 80 5.1E-12 T 29-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA A616_RS26905 ed86dbabdea16d7fc98715b8b0c4503c 404 SUPERFAMILY SSF54966 4 114 2.22E-24 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A616_RS26905 ed86dbabdea16d7fc98715b8b0c4503c 404 Gene3D G3DSA:3.20.20.110 115 404 2.5E-93 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A616_RS26905 ed86dbabdea16d7fc98715b8b0c4503c 404 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 6 401 4.3E-158 T 29-03-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 A616_RS26905 ed86dbabdea16d7fc98715b8b0c4503c 404 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 120 400 1.7E-45 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A616_RS26905 ed86dbabdea16d7fc98715b8b0c4503c 404 SUPERFAMILY SSF51649 114 402 5.63E-88 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A616_RS26905 ed86dbabdea16d7fc98715b8b0c4503c 404 Gene3D G3DSA:3.30.70.150 1 114 7.9E-26 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A616_RS01130 71f8232cc6d739e23b0ec05c60980d9b 66 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 60 17.235 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A616_RS01130 71f8232cc6d739e23b0ec05c60980d9b 66 Pfam PF02416 mttA/Hcf106 family 5 55 8.7E-21 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A616_RS01130 71f8232cc6d739e23b0ec05c60980d9b 66 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 49 1.1E-18 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A616_RS01130 71f8232cc6d739e23b0ec05c60980d9b 66 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 3.3E-5 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A616_RS01130 71f8232cc6d739e23b0ec05c60980d9b 66 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 3.3E-5 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A616_RS30350 daa8ff2dc51f6b6ae616f98a5a42c01e 302 SUPERFAMILY SSF55729 1 290 5.49E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS30350 daa8ff2dc51f6b6ae616f98a5a42c01e 302 Gene3D G3DSA:3.40.630.30 1 151 1.0E-21 T 29-03-2018 A616_RS30350 daa8ff2dc51f6b6ae616f98a5a42c01e 302 Gene3D G3DSA:3.40.630.30 152 300 0.095 T 29-03-2018 A616_RS30350 daa8ff2dc51f6b6ae616f98a5a42c01e 302 Pfam PF00583 Acetyltransferase (GNAT) family 49 133 3.2E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS13830 a49b92520ab1649761f8e2b122548943 272 Gene3D G3DSA:3.20.20.70 4 272 3.7E-76 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS13830 a49b92520ab1649761f8e2b122548943 272 SUPERFAMILY SSF51366 6 246 3.86E-84 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS13830 a49b92520ab1649761f8e2b122548943 272 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 49 62 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS13830 a49b92520ab1649761f8e2b122548943 272 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 13 267 6.2E-87 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS13830 a49b92520ab1649761f8e2b122548943 272 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 15 270 37.398 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS13830 a49b92520ab1649761f8e2b122548943 272 Pfam PF00290 Tryptophan synthase alpha chain 14 250 6.6E-92 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A616_RS12315 dc79c13b6686b1d72fce7cca67285d1b 285 Gene3D G3DSA:3.40.1090.10 2 261 2.9E-34 T 29-03-2018 A616_RS12315 dc79c13b6686b1d72fce7cca67285d1b 285 SUPERFAMILY SSF52151 3 271 9.94E-44 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A616_RS12315 dc79c13b6686b1d72fce7cca67285d1b 285 Pfam PF01734 Patatin-like phospholipase 6 169 1.8E-20 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A616_RS02735 3e38027e6e53d8b6f065ecdfa16259e1 85 SUPERFAMILY SSF109998 24 80 2.98E-5 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS02735 3e38027e6e53d8b6f065ecdfa16259e1 85 Gene3D G3DSA:1.10.10.10 11 84 0.0011 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13735 8b44df417beac7b3ef34ed043835f179 236 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 121 149 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A616_RS13735 8b44df417beac7b3ef34ed043835f179 236 Pfam PF01464 Transglycosylase SLT domain 105 198 5.0E-26 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 A616_RS13735 8b44df417beac7b3ef34ed043835f179 236 SUPERFAMILY SSF53955 87 229 1.83E-37 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS13735 8b44df417beac7b3ef34ed043835f179 236 Gene3D G3DSA:1.10.530.10 56 232 1.1E-37 T 29-03-2018 A616_RS12490 25e699af9b631d06948f9db64427685c 183 SMART SM00530 7 62 2.6E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS12490 25e699af9b631d06948f9db64427685c 183 SUPERFAMILY SSF47413 3 67 1.18E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS12490 25e699af9b631d06948f9db64427685c 183 Pfam PF07883 Cupin domain 108 175 1.5E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS12490 25e699af9b631d06948f9db64427685c 183 Gene3D G3DSA:2.60.120.10 76 181 6.8E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS12490 25e699af9b631d06948f9db64427685c 183 Pfam PF01381 Helix-turn-helix 8 62 2.4E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS12490 25e699af9b631d06948f9db64427685c 183 Gene3D G3DSA:1.10.260.40 2 75 2.8E-15 T 29-03-2018 A616_RS12490 25e699af9b631d06948f9db64427685c 183 SUPERFAMILY SSF51182 55 179 1.11E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS07600 440225cc156d473abc963ea6561c172a 198 Gene3D G3DSA:1.10.10.60 1 58 3.0E-15 T 29-03-2018 A616_RS07600 440225cc156d473abc963ea6561c172a 198 SUPERFAMILY SSF46689 2 71 1.8E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS07600 440225cc156d473abc963ea6561c172a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS07600 440225cc156d473abc963ea6561c172a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS07600 440225cc156d473abc963ea6561c172a 198 SUPERFAMILY SSF48498 77 181 2.49E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A616_RS07600 440225cc156d473abc963ea6561c172a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 3.7E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A616_RS07600 440225cc156d473abc963ea6561c172a 198 Gene3D G3DSA:1.10.357.10 59 183 6.4E-23 T 29-03-2018 A616_RS04825 0726c12f12954930b5ff35f00a36ee5a 235 Gene3D G3DSA:3.40.50.1820 20 234 6.4E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS04825 0726c12f12954930b5ff35f00a36ee5a 235 SUPERFAMILY SSF53474 11 232 1.75E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 SUPERFAMILY SSF50331 236 338 1.12E-13 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 Pfam PF08402 TOBE domain 254 330 4.0E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 SMART SM00382 28 211 2.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 Pfam PF00005 ABC transporter 20 161 9.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 Gene3D G3DSA:3.40.50.300 2 249 1.5E-72 T 29-03-2018 A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 SUPERFAMILY SSF52540 4 242 1.11E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30490 d19db56f43ca8e41141ac9ec2f716f19 355 Gene3D G3DSA:2.40.50.140 255 323 5.1E-9 T 29-03-2018 A616_RS01845 64e4c5e19594fdd9b941e6d27dfbf61f 307 Gene3D G3DSA:3.90.1200.10 104 272 1.4E-16 T 29-03-2018 A616_RS01845 64e4c5e19594fdd9b941e6d27dfbf61f 307 SUPERFAMILY SSF56112 19 260 4.08E-31 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS01845 64e4c5e19594fdd9b941e6d27dfbf61f 307 Pfam PF01636 Phosphotransferase enzyme family 25 264 7.4E-25 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS21750 52bd87ccd04cc8b8c888a8e7b1ac98e9 81 SUPERFAMILY SSF48619 2 77 2.1E-17 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A616_RS21750 52bd87ccd04cc8b8c888a8e7b1ac98e9 81 ProSitePatterns PS00118 Phospholipase A2 histidine active site. 23 30 - T 29-03-2018 IPR033113 Phospholipase A2, histidine active site KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783|Reactome: R-HSA-1482788|Reactome: R-HSA-1482801|Reactome: R-HSA-1482839|Reactome: R-HSA-1482922|Reactome: R-HSA-1482925|Reactome: R-HSA-1483166 A616_RS21750 52bd87ccd04cc8b8c888a8e7b1ac98e9 81 Pfam PF00068 Phospholipase A2 2 33 2.2E-7 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A616_RS21750 52bd87ccd04cc8b8c888a8e7b1ac98e9 81 Gene3D G3DSA:1.20.90.10 1 36 3.6E-9 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A616_RS21750 52bd87ccd04cc8b8c888a8e7b1ac98e9 81 Gene3D G3DSA:1.20.90.10 37 75 0.038 T 29-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 A616_RS24415 e5bc7fc39a132d955fa411a260ee0545 253 Gene3D G3DSA:3.40.50.1820 9 252 4.6E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24415 e5bc7fc39a132d955fa411a260ee0545 253 Pfam PF00561 alpha/beta hydrolase fold 25 128 2.8E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS24415 e5bc7fc39a132d955fa411a260ee0545 253 SUPERFAMILY SSF53474 7 243 1.17E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 360 1.8E-141 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 Gene3D G3DSA:3.40.50.620 1 212 1.7E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 Gene3D G3DSA:2.40.30.10 282 370 3.4E-30 T 29-03-2018 A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 SUPERFAMILY SSF52402 6 244 3.31E-61 T 29-03-2018 A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 Pfam PF03054 tRNA methyl transferase 8 360 1.7E-147 T 29-03-2018 A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 361 42.082 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A616_RS18215 5f4b0cd69e65f99c835ebc23870a99dd 370 Gene3D G3DSA:2.30.30.280 213 280 6.2E-27 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 A616_RS05970 5f5c7097823cf0d032395adfd6aee740 156 Gene3D G3DSA:3.40.30.10 1 155 6.0E-42 T 29-03-2018 A616_RS05970 5f5c7097823cf0d032395adfd6aee740 156 PIRSF PIRSF000239 1 155 2.6E-30 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS05970 5f5c7097823cf0d032395adfd6aee740 156 SUPERFAMILY SSF52833 3 152 3.03E-55 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS05970 5f5c7097823cf0d032395adfd6aee740 156 Pfam PF00578 AhpC/TSA family 4 132 2.9E-41 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS25630 830e6bc90300fc37e955eb1dd4b9f37d 582 Gene3D G3DSA:3.40.190.10 247 339 2.1E-19 T 29-03-2018 A616_RS25630 830e6bc90300fc37e955eb1dd4b9f37d 582 Gene3D G3DSA:3.90.76.10 87 246 1.1E-38 T 29-03-2018 A616_RS25630 830e6bc90300fc37e955eb1dd4b9f37d 582 Gene3D G3DSA:3.10.105.10 340 552 1.3E-56 T 29-03-2018 A616_RS25630 830e6bc90300fc37e955eb1dd4b9f37d 582 PIRSF PIRSF002741 3 575 1.1E-110 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A616_RS25630 830e6bc90300fc37e955eb1dd4b9f37d 582 SUPERFAMILY SSF53850 71 572 1.23E-125 T 29-03-2018 A616_RS25630 830e6bc90300fc37e955eb1dd4b9f37d 582 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 117 498 6.7E-86 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain A616_RS23390 76d768a81255ad648fb331f9b308e265 215 Pfam PF02397 Bacterial sugar transferase 2 177 2.7E-62 T 29-03-2018 IPR003362 Bacterial sugar transferase A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 SUPERFAMILY SSF102712 133 198 2.09E-5 T 29-03-2018 A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 Gene3D G3DSA:1.10.150.20 48 97 2.5E-9 T 29-03-2018 A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 TIGRFAM TIGR00608 radc: DNA repair protein RadC 19 232 1.1E-77 T 29-03-2018 IPR001405 RadC protein A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 SUPERFAMILY SSF47781 24 98 4.08E-11 T 29-03-2018 IPR010994 RuvA domain 2-like A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 181 186 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 Gene3D G3DSA:3.40.140.10 107 232 2.1E-50 T 29-03-2018 A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 Pfam PF04002 RadC-like JAB domain 113 230 1.7E-46 T 29-03-2018 IPR025657 RadC-like JAB domain A616_RS10490 ba691df0a36744b84543d8f5bfb01924 232 Pfam PF12826 Helix-hairpin-helix motif 53 95 1.3E-6 T 29-03-2018 A616_RS09810 5889776379fbe6a98b356c1426f4232a 152 Gene3D G3DSA:3.40.1550.10 1 152 9.5E-31 T 29-03-2018 IPR028976 CheC-like domain A616_RS09810 5889776379fbe6a98b356c1426f4232a 152 Pfam PF13690 Chemotaxis phosphatase CheX 46 124 7.5E-14 T 29-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain A616_RS09810 5889776379fbe6a98b356c1426f4232a 152 SUPERFAMILY SSF103039 1 124 1.31E-29 T 29-03-2018 IPR028976 CheC-like domain A616_RS20380 4d9da0a42882285582439c8444849a21 584 Pfam PF13667 ThiC-associated domain 6 83 5.4E-28 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A616_RS20380 4d9da0a42882285582439c8444849a21 584 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 125 552 56.834 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A616_RS20380 4d9da0a42882285582439c8444849a21 584 Pfam PF01964 Radical SAM ThiC family 126 546 1.1E-203 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A616_RS20380 4d9da0a42882285582439c8444849a21 584 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 125 549 4.2E-221 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A616_RS30335 d082d5cc3d53a4131aff7616212e37a4 911 Pfam PF16147 Domain of unknown function (DUF4855) 579 893 3.7E-100 T 29-03-2018 IPR032329 Protein of unknown function DUF4855 A616_RS30335 d082d5cc3d53a4131aff7616212e37a4 911 Pfam PF00395 S-layer homology domain 65 106 5.0E-7 T 29-03-2018 IPR001119 S-layer homology domain A616_RS30335 d082d5cc3d53a4131aff7616212e37a4 911 Pfam PF00395 S-layer homology domain 190 232 8.6E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS30335 d082d5cc3d53a4131aff7616212e37a4 911 Pfam PF00395 S-layer homology domain 125 167 6.2E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS30335 d082d5cc3d53a4131aff7616212e37a4 911 Gene3D G3DSA:2.60.120.260 177 555 5.8E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 SMART SM00357 3 66 1.1E-26 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 1.7E-28 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 SUPERFAMILY SSF50249 1 64 1.31E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 Gene3D G3DSA:2.40.50.140 1 66 9.0E-27 T 29-03-2018 A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 PIRSF PIRSF002599 1 67 3.0E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 PRINTS PR00050 Cold shock protein signature 24 33 1.4E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 PRINTS PR00050 Cold shock protein signature 39 57 1.4E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS24160 9106b9b061d108f422fa475cf0805f08 68 PRINTS PR00050 Cold shock protein signature 4 19 1.4E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 Gene3D G3DSA:3.90.1310.10 27 426 7.9E-46 T 29-03-2018 A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 410 1.0E-40 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 SUPERFAMILY SSF56601 378 794 5.12E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 Gene3D G3DSA:3.40.710.10 427 795 5.6E-84 T 29-03-2018 A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 SUPERFAMILY SSF56519 53 122 3.3E-28 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 SUPERFAMILY SSF56519 294 425 3.3E-28 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A616_RS10510 93c8314b0edfe285923b68d29c855d70 810 Pfam PF00905 Penicillin binding protein transpeptidase domain 461 786 2.1E-68 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS02055 73d07e1ce98c7efeacc2fa53e759c797 408 SUPERFAMILY SSF103473 6 398 2.96E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS02055 73d07e1ce98c7efeacc2fa53e759c797 408 Gene3D G3DSA:1.20.1250.20 206 406 2.5E-17 T 29-03-2018 A616_RS02055 73d07e1ce98c7efeacc2fa53e759c797 408 Pfam PF07690 Major Facilitator Superfamily 13 234 6.4E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS02055 73d07e1ce98c7efeacc2fa53e759c797 408 Gene3D G3DSA:1.20.1250.20 3 201 1.6E-27 T 29-03-2018 A616_RS09020 1197893393df78d92ba4ae640727aa89 287 Pfam PF13739 Domain of unknown function (DUF4163) 88 162 2.7E-7 T 29-03-2018 IPR025303 Deacetylase PdaC A616_RS09020 1197893393df78d92ba4ae640727aa89 287 Pfam PF11738 Protein of unknown function (DUF3298) 194 273 2.2E-18 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 A616_RS09020 1197893393df78d92ba4ae640727aa89 287 Gene3D G3DSA:3.90.640.20 190 287 4.1E-26 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 A616_RS09020 1197893393df78d92ba4ae640727aa89 287 Gene3D G3DSA:3.30.565.40 75 189 3.8E-11 T 29-03-2018 A616_RS28010 ff2ea522a7d3583099258b18f76985ec 294 Gene3D G3DSA:3.90.550.10 2 280 1.0E-14 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28010 ff2ea522a7d3583099258b18f76985ec 294 SUPERFAMILY SSF53448 189 258 2.06E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28010 ff2ea522a7d3583099258b18f76985ec 294 SUPERFAMILY SSF53448 7 156 2.06E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 304 5.3E-122 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.3E-73 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 293 4.7E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 1.8E-36 T 29-03-2018 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.8E-36 T 29-03-2018 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.8E-36 T 29-03-2018 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.8E-36 T 29-03-2018 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.8E-36 T 29-03-2018 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 SUPERFAMILY SSF51905 2 301 1.35E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 Gene3D G3DSA:3.50.50.60 128 182 1.1E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 Gene3D G3DSA:3.50.50.60 1 127 6.5E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS29150 9a733abcd56292ddaefb74083a1fefb9 319 Gene3D G3DSA:3.50.50.60 183 312 8.7E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS02585 20622d0149db93189f7d4824868c7217 442 Pfam PF13559 Domain of unknown function (DUF4129) 361 432 1.6E-7 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 A616_RS11600 796cb7866139315d236f35c94c5afcea 447 SUPERFAMILY SSF141322 384 443 2.22E-6 T 29-03-2018 A616_RS11600 796cb7866139315d236f35c94c5afcea 447 SUPERFAMILY SSF52096 35 209 5.24E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS11600 796cb7866139315d236f35c94c5afcea 447 Gene3D G3DSA:3.90.226.10 30 216 9.5E-28 T 29-03-2018 A616_RS11600 796cb7866139315d236f35c94c5afcea 447 Pfam PF01957 NfeD-like C-terminal, partner-binding 296 442 6.8E-16 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain A616_RS11600 796cb7866139315d236f35c94c5afcea 447 Gene3D G3DSA:2.40.50.140 382 447 6.1E-11 T 29-03-2018 A616_RS11600 796cb7866139315d236f35c94c5afcea 447 Pfam PF01972 Serine dehydrogenase proteinase 63 136 3.1E-9 T 29-03-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A616_RS24380 665a3ad28e51e68ba6ba9d6e86d1e206 207 Pfam PF09335 SNARE associated Golgi protein 48 147 5.3E-14 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS29690 5f6dc270439e5db240a2d10ffbb9a0f5 499 SUPERFAMILY SSF54001 345 463 3.83E-5 T 29-03-2018 A616_RS22555 68c2f11942d569bdf66083e91c22a33b 173 Gene3D G3DSA:3.40.30.10 21 171 3.5E-25 T 29-03-2018 A616_RS22555 68c2f11942d569bdf66083e91c22a33b 173 ProSitePatterns PS01265 Tpx family signature. 90 101 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 A616_RS22555 68c2f11942d569bdf66083e91c22a33b 173 Hamap MF_00269 Probable thiol peroxidase [tpx]. 10 170 36.673 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 A616_RS22555 68c2f11942d569bdf66083e91c22a33b 173 Pfam PF08534 Redoxin 26 166 1.0E-19 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 A616_RS22555 68c2f11942d569bdf66083e91c22a33b 173 SUPERFAMILY SSF52833 12 167 2.09E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS00700 0f70468e00e3d672c1b491c469e7b902 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 68 1.5E-20 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 A616_RS00700 0f70468e00e3d672c1b491c469e7b902 76 ProDom PD057826 YABK 4 76 8.0E-10 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 A616_RS12420 d5f9f6f5eb9adc9b563d25dc739588f5 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 32 3.4E-10 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS12420 d5f9f6f5eb9adc9b563d25dc739588f5 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 30 2.9E-8 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS25960 13b33d03e44bc3dbfb9cdc65e7a0a155 297 Pfam PF03547 Membrane transport protein 154 292 1.1E-15 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A616_RS25960 13b33d03e44bc3dbfb9cdc65e7a0a155 297 Pfam PF03547 Membrane transport protein 4 142 1.1E-8 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 SUPERFAMILY SSF47729 1 90 1.12E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 SMART SM00411 1 90 3.6E-50 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.7E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.7E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.7E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.6E-37 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A616_RS13720 67d8b3e60c170f46239269409a0f6cdf 90 Gene3D G3DSA:4.10.520.10 1 90 2.5E-38 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A616_RS20515 19b1d21999eb818bcd3d0d971c20e9b5 326 Pfam PF01944 Stage II sporulation protein M 111 285 9.6E-41 T 29-03-2018 IPR002798 Stage II sporulation protein M-like A616_RS26240 a1358d803a42ae35219879f4b27e5399 158 Pfam PF02681 Divergent PAP2 family 6 150 1.3E-49 T 29-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF14903 WG containing repeat 206 240 3.2E-6 T 29-03-2018 IPR032774 WG containing repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF14903 WG containing repeat 240 276 2.7E-7 T 29-03-2018 IPR032774 WG containing repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF14903 WG containing repeat 276 311 1.6E-7 T 29-03-2018 IPR032774 WG containing repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 SUPERFAMILY SSF81901 594 810 2.35E-40 T 29-03-2018 A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 SMART SM00671 592 623 58.0 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 SMART SM00671 695 730 2.6E-6 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 SMART SM00671 762 797 0.0026 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 SMART SM00671 659 694 2.7E-8 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 SMART SM00671 624 658 0.17 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Gene3D G3DSA:2.60.40.1180 640 730 2.4E-21 T 29-03-2018 A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Gene3D G3DSA:2.60.40.1180 557 639 2.8E-5 T 29-03-2018 A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Gene3D G3DSA:2.60.40.1180 737 834 4.4E-14 T 29-03-2018 A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF08238 Sel1 repeat 595 622 100.0 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF08238 Sel1 repeat 764 796 5.9E-4 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF08238 Sel1 repeat 696 725 0.0016 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF08238 Sel1 repeat 660 694 4.4E-8 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF08238 Sel1 repeat 625 658 7.2E-4 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS24935 b5d2f7495714bb4c1e43b9caa7b132ce 841 Pfam PF08238 Sel1 repeat 741 755 37.0 T 29-03-2018 IPR006597 Sel1-like repeat A616_RS11055 7372b969dd6cf459bfac9dfec2ae9843 322 SUPERFAMILY SSF55729 124 309 1.72E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS11055 7372b969dd6cf459bfac9dfec2ae9843 322 Gene3D G3DSA:3.40.630.30 175 320 7.8E-17 T 29-03-2018 A616_RS11055 7372b969dd6cf459bfac9dfec2ae9843 322 Gene3D G3DSA:3.40.630.30 1 174 2.0E-5 T 29-03-2018 A616_RS11055 7372b969dd6cf459bfac9dfec2ae9843 322 Pfam PF00583 Acetyltransferase (GNAT) family 219 305 4.1E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 Gene3D G3DSA:3.40.50.720 1 43 2.4E-11 T 29-03-2018 A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 Gene3D G3DSA:3.40.50.720 44 226 1.7E-51 T 29-03-2018 A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 SUPERFAMILY SSF51735 3 225 6.1E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 Pfam PF00106 short chain dehydrogenase 8 196 4.6E-65 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PIRSF PIRSF000126 3 238 2.3E-65 T 29-03-2018 A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.5E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.6E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.6E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS12445 12c4c2568fd61b770a1f07b06b1e447d 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.6E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS21135 ddba7cc9a2cfb591e9124556efd29993 84 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 52 1.0E-13 T 29-03-2018 IPR024255 Spore germination GerPB A616_RS21135 ddba7cc9a2cfb591e9124556efd29993 84 Pfam PF10803 Spore germination GerPB 1 52 1.7E-30 T 29-03-2018 IPR024255 Spore germination GerPB A616_RS16220 77a1ccc14c949c6116cefd69876de143 153 Gene3D G3DSA:3.30.1330.40 1 153 1.1E-28 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS16220 77a1ccc14c949c6116cefd69876de143 153 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 9 151 1.4E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS16220 77a1ccc14c949c6116cefd69876de143 153 SUPERFAMILY SSF55298 7 151 5.18E-52 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS02825 d8160f6d76aba4a240340668efc6fbbe 200 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 61 174 6.0E-20 T 29-03-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 A616_RS32090 0fc6dab9e782b342699b865ca4c77d51 80 Pfam PF14116 YyzF-like protein 26 71 1.6E-13 T 29-03-2018 IPR025626 YyzF-like protein A616_RS32090 0fc6dab9e782b342699b865ca4c77d51 80 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 25 73 7.9E-15 T 29-03-2018 IPR025626 YyzF-like protein A616_RS25775 1565967311ad77231445063cca3d2ed5 318 SMART SM00420 5 57 0.0083 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A616_RS25775 1565967311ad77231445063cca3d2ed5 318 Pfam PF08279 HTH domain 5 58 2.8E-16 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS25775 1565967311ad77231445063cca3d2ed5 318 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A616_RS25775 1565967311ad77231445063cca3d2ed5 318 PIRSF PIRSF016838 1 318 4.6E-17 T 29-03-2018 IPR028349 Protein PafC A616_RS25775 1565967311ad77231445063cca3d2ed5 318 Gene3D G3DSA:1.10.10.10 1 83 4.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25775 1565967311ad77231445063cca3d2ed5 318 SUPERFAMILY SSF46785 2 58 9.52E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25775 1565967311ad77231445063cca3d2ed5 318 Pfam PF13280 WYL domain 140 311 1.9E-38 T 29-03-2018 IPR026881 WYL domain A616_RS09860 6e53e2438f692f70835c4db855f9a685 72 Gene3D G3DSA:2.30.130.30 1 65 7.3E-15 T 29-03-2018 A616_RS09860 6e53e2438f692f70835c4db855f9a685 72 SUPERFAMILY SSF88697 2 54 2.39E-5 T 29-03-2018 IPR015947 PUA-like domain A616_RS09860 6e53e2438f692f70835c4db855f9a685 72 Pfam PF12961 Domain of Unknown Function with PDB structure (DUF3850) 3 62 6.8E-17 T 29-03-2018 A616_RS30900 7e2191e2681c48162f110651dfc0c102 193 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 8 189 2.0E-46 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS30900 7e2191e2681c48162f110651dfc0c102 193 SUPERFAMILY SSF53187 5 192 1.95E-46 T 29-03-2018 A616_RS30900 7e2191e2681c48162f110651dfc0c102 193 Gene3D G3DSA:3.40.630.40 3 193 3.0E-54 T 29-03-2018 A616_RS30900 7e2191e2681c48162f110651dfc0c102 193 SMART SM00646 78 189 4.2E-28 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS07595 69f9e9d24f39e70eab75acaf3da8caf5 160 Gene3D G3DSA:1.20.120.450 1 152 7.2E-16 T 29-03-2018 A616_RS07595 69f9e9d24f39e70eab75acaf3da8caf5 160 Pfam PF12867 DinB superfamily 8 147 3.9E-17 T 29-03-2018 IPR024775 DinB-like domain A616_RS07595 69f9e9d24f39e70eab75acaf3da8caf5 160 SUPERFAMILY SSF109854 4 147 5.13E-17 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS15970 719581fdc3a29b79f7ed313b2985f3f1 43 Gene3D G3DSA:3.40.140.10 1 36 1.7E-5 T 29-03-2018 A616_RS15495 dfa604c3e065a3e9a45f4c3448e44def 191 Gene3D G3DSA:3.40.190.10 1 174 4.0E-4 T 29-03-2018 A616_RS32245 877cb1109a97be9e0ed1edbeb8c36f93 384 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 4 379 1.7E-143 T 29-03-2018 IPR010969 Cysteine desulfurase-related, unknown function A616_RS32245 877cb1109a97be9e0ed1edbeb8c36f93 384 PIRSF PIRSF005572 1 384 7.7E-55 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A616_RS32245 877cb1109a97be9e0ed1edbeb8c36f93 384 Gene3D G3DSA:3.90.1150.10 256 379 8.3E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS32245 877cb1109a97be9e0ed1edbeb8c36f93 384 Gene3D G3DSA:3.40.640.10 15 255 2.5E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS32245 877cb1109a97be9e0ed1edbeb8c36f93 384 Pfam PF00266 Aminotransferase class-V 4 372 1.3E-88 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS32245 877cb1109a97be9e0ed1edbeb8c36f93 384 SUPERFAMILY SSF53383 3 380 1.01E-99 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.2E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.2E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.2E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 Pfam PF00381 PTS HPr component phosphorylation site 6 82 3.5E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 SUPERFAMILY SSF55594 3 85 4.58E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 5 82 4.0E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS30985 75c6268b20fec34b31f99726d23a3468 87 Gene3D G3DSA:3.30.1340.10 1 87 6.0E-26 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 SUPERFAMILY SSF55681 4 241 9.94E-80 T 29-03-2018 A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 Gene3D G3DSA:3.30.390.50 244 329 1.7E-22 T 29-03-2018 A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 243 327 3.0E-27 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 Gene3D G3DSA:3.30.930.10 1 243 2.3E-70 T 29-03-2018 A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 SUPERFAMILY SSF82649 242 327 1.31E-22 T 29-03-2018 A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 151 1.6E-11 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A616_RS25810 0d4a21ce7cdf17646cf0b98e87955aa6 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 320 7.9E-121 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 SMART SM00849 20 215 2.8E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 411 2.3E-11 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 Pfam PF00753 Metallo-beta-lactamase superfamily 18 166 1.2E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 SUPERFAMILY SSF56281 10 427 8.37E-98 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 PIRSF PIRSF004803 1 558 7.2E-242 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 Gene3D G3DSA:3.60.15.10 2 451 3.7E-66 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 556 2.2E-205 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 367 395 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site A616_RS19720 abb48eca0e65e747254ee2a06d064d8a 558 Hamap MF_01491 Ribonuclease J [rnj]. 3 558 48.078 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 A616_RS03440 6267b272653e530c370c186eb74aace7 481 Pfam PF00092 von Willebrand factor type A domain 178 363 2.6E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03440 6267b272653e530c370c186eb74aace7 481 SUPERFAMILY SSF53300 177 363 4.45E-27 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03440 6267b272653e530c370c186eb74aace7 481 Gene3D G3DSA:3.40.50.410 171 481 1.2E-32 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03440 6267b272653e530c370c186eb74aace7 481 SMART SM00327 175 366 2.4E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27470 183d63fe82ce2a1345f5a067e1e60d15 292 Gene3D G3DSA:1.10.3470.10 1 277 6.7E-49 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS27470 183d63fe82ce2a1345f5a067e1e60d15 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 9.0E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS05930 922d7a1feed310e41f36e5ba2a8cfb38 287 Gene3D G3DSA:3.60.40.10 11 287 1.1E-14 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS05930 922d7a1feed310e41f36e5ba2a8cfb38 287 Pfam PF13672 Protein phosphatase 2C 17 229 5.2E-13 T 29-03-2018 A616_RS05930 922d7a1feed310e41f36e5ba2a8cfb38 287 SUPERFAMILY SSF81606 203 211 1.29E-12 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS05930 922d7a1feed310e41f36e5ba2a8cfb38 287 SUPERFAMILY SSF81606 8 158 1.29E-12 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS18255 fddbbeaa18d421318a3a0dcac722a2cd 186 Pfam PF00583 Acetyltransferase (GNAT) family 63 153 1.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS18255 fddbbeaa18d421318a3a0dcac722a2cd 186 SUPERFAMILY SSF55729 14 182 5.49E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS18255 fddbbeaa18d421318a3a0dcac722a2cd 186 Gene3D G3DSA:3.40.630.30 13 181 9.6E-29 T 29-03-2018 A616_RS23610 01877a904f9cb377a4f4a92f78230936 436 Pfam PF03600 Citrate transporter 13 382 1.1E-53 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A616_RS23610 01877a904f9cb377a4f4a92f78230936 436 TIGRFAM TIGR00784 citMHS: citrate transporter 1 436 3.3E-199 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 A616_RS20460 6c1156e5148fe06034ad8232300e11ad 371 Gene3D G3DSA:3.40.1830.10 2 164 9.5E-47 T 29-03-2018 IPR035097 Peptidase M29, N-terminal A616_RS20460 6c1156e5148fe06034ad8232300e11ad 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 335 1.0E-62 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 A616_RS20460 6c1156e5148fe06034ad8232300e11ad 371 SUPERFAMILY SSF144052 1 358 1.96E-112 T 29-03-2018 A616_RS03365 b26768d994b319df183b5071b939d717 468 Gene3D G3DSA:3.40.50.2000 279 451 9.1E-33 T 29-03-2018 A616_RS03365 b26768d994b319df183b5071b939d717 468 SUPERFAMILY SSF53756 139 465 1.62E-58 T 29-03-2018 A616_RS03365 b26768d994b319df183b5071b939d717 468 SUPERFAMILY SSF53756 2 54 1.62E-58 T 29-03-2018 A616_RS03365 b26768d994b319df183b5071b939d717 468 Pfam PF11997 Domain of unknown function (DUF3492) 1 259 1.3E-78 T 29-03-2018 IPR022622 Domain of unknown function DUF3492 A616_RS03365 b26768d994b319df183b5071b939d717 468 Gene3D G3DSA:3.40.50.2000 89 278 2.2E-4 T 29-03-2018 A616_RS03365 b26768d994b319df183b5071b939d717 468 Pfam PF00534 Glycosyl transferases group 1 279 442 4.0E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 Gene3D G3DSA:2.30.38.10 322 403 1.0E-26 T 29-03-2018 A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 Pfam PF00501 AMP-binding enzyme 10 410 2.6E-117 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 165 176 - T 29-03-2018 IPR020845 AMP-binding, conserved site A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 Gene3D G3DSA:3.40.50.980 2 170 4.6E-46 T 29-03-2018 A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 493 2.2E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 Gene3D G3DSA:3.30.300.30 404 502 1.1E-29 T 29-03-2018 A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 SUPERFAMILY SSF56801 4 500 4.71E-164 T 29-03-2018 A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 PRINTS PR00154 AMP-binding signature 160 171 6.7E-5 T 29-03-2018 IPR020459 AMP-binding A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 PRINTS PR00154 AMP-binding signature 172 180 6.7E-5 T 29-03-2018 IPR020459 AMP-binding A616_RS18100 44e2bbeaa0c5fab8cfe9d96c92353f69 502 Gene3D G3DSA:3.40.50.980 171 321 7.8E-52 T 29-03-2018 A616_RS02710 1e1b83b73e63a0d32083463eaa95ad38 149 Gene3D G3DSA:3.30.530.20 1 142 5.1E-22 T 29-03-2018 IPR023393 START-like domain A616_RS02710 1e1b83b73e63a0d32083463eaa95ad38 149 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 140 2.8E-16 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS02710 1e1b83b73e63a0d32083463eaa95ad38 149 SUPERFAMILY SSF55961 1 146 3.67E-26 T 29-03-2018 A616_RS03915 466f1df890664351e76e7f2bc96f1bce 384 Pfam PF00899 ThiF family 121 346 1.2E-47 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS03915 466f1df890664351e76e7f2bc96f1bce 384 SUPERFAMILY SSF69572 95 366 2.35E-53 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS03915 466f1df890664351e76e7f2bc96f1bce 384 Gene3D G3DSA:3.40.50.720 93 366 9.3E-53 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 SUPERFAMILY SSF58104 304 572 1.26E-59 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 SUPERFAMILY SSF58104 245 271 1.26E-59 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 Pfam PF00672 HAMP domain 217 266 3.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 243 573 1.0E-4 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 Gene3D G3DSA:1.10.287.950 324 499 2.6E-42 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 Gene3D G3DSA:1.10.287.950 237 323 2.2E-7 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 Gene3D G3DSA:1.10.287.950 500 572 7.0E-7 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 10 35 3.0E-19 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 425 454 3.0E-19 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 423 3.0E-19 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 SMART SM00283 298 573 9.3E-50 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 Gene3D G3DSA:3.30.450.20 28 186 1.0E-11 T 29-03-2018 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 367 526 4.1E-38 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 SUPERFAMILY SSF103190 64 180 4.32E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like A616_RS27615 a2c97b2f34386437806beeb37457bcac 574 SMART SM00304 215 269 2.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 SUPERFAMILY SSF52540 337 575 1.0E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 11 536 2.5E-157 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 Pfam PF00005 ABC transporter 360 505 1.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 Gene3D G3DSA:3.40.50.300 326 577 1.3E-65 T 29-03-2018 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 SMART SM00382 368 552 2.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 SUPERFAMILY SSF90123 11 306 1.18E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 SUPERFAMILY SSF90123 482 491 1.18E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS25400 cfcd888eec44e4042316e610a9b07ae8 585 Gene3D G3DSA:1.20.1560.10 2 325 2.0E-27 T 29-03-2018 A616_RS24755 ab597e43b08fbb693cc1ad69fa3abe27 206 SUPERFAMILY SSF53474 3 200 2.54E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24755 ab597e43b08fbb693cc1ad69fa3abe27 206 Gene3D G3DSA:3.40.50.1820 1 201 2.9E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24755 ab597e43b08fbb693cc1ad69fa3abe27 206 Pfam PF01738 Dienelactone hydrolase family 85 184 6.0E-7 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 A616_RS24975 4caa6236be8e731edc0b2f04527cbae8 374 Gene3D G3DSA:3.40.190.10 174 328 4.1E-34 T 29-03-2018 A616_RS24975 4caa6236be8e731edc0b2f04527cbae8 374 Pfam PF13343 Bacterial extracellular solute-binding protein 108 345 8.0E-36 T 29-03-2018 A616_RS24975 4caa6236be8e731edc0b2f04527cbae8 374 PIRSF PIRSF002825 11 369 8.6E-72 T 29-03-2018 IPR026045 Ferric binding protein A616_RS24975 4caa6236be8e731edc0b2f04527cbae8 374 Gene3D G3DSA:3.40.190.10 41 173 2.6E-14 T 29-03-2018 A616_RS24975 4caa6236be8e731edc0b2f04527cbae8 374 SUPERFAMILY SSF53850 61 366 1.4E-70 T 29-03-2018 A616_RS03715 f77f78dce81fc62bbe6b40aa12238066 867 Gene3D G3DSA:2.60.120.260 150 281 1.5E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS03715 f77f78dce81fc62bbe6b40aa12238066 867 Gene3D G3DSA:2.60.120.260 11 128 7.3E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS03715 f77f78dce81fc62bbe6b40aa12238066 867 Gene3D G3DSA:2.60.120.260 400 540 9.2E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS03715 f77f78dce81fc62bbe6b40aa12238066 867 SUPERFAMILY SSF49785 402 517 1.13E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS28870 791ed2f59d5910a8c693754bc07d19a3 522 Gene3D G3DSA:3.40.50.620 169 327 0.1 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS04610 2d773e10b43c4834ae3268bf7bdc8a30 318 Gene3D G3DSA:3.30.420.40 1 125 1.9E-34 T 29-03-2018 A616_RS04610 2d773e10b43c4834ae3268bf7bdc8a30 318 ProSitePatterns PS01125 ROK family signature. 140 167 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS04610 2d773e10b43c4834ae3268bf7bdc8a30 318 Pfam PF00480 ROK family 8 302 1.3E-75 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS04610 2d773e10b43c4834ae3268bf7bdc8a30 318 Gene3D G3DSA:3.30.420.40 126 311 7.2E-61 T 29-03-2018 A616_RS04610 2d773e10b43c4834ae3268bf7bdc8a30 318 SUPERFAMILY SSF53067 6 302 7.78E-69 T 29-03-2018 A616_RS29375 5cb9476a5fe89fdb334c28b31fa408f4 129 PIRSF PIRSF000025 1 129 1.1E-30 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A616_RS29375 5cb9476a5fe89fdb334c28b31fa408f4 129 SUPERFAMILY SSF46626 5 127 9.31E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS29375 5cb9476a5fe89fdb334c28b31fa408f4 129 Gene3D G3DSA:1.10.760.10 23 128 2.5E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS29375 5cb9476a5fe89fdb334c28b31fa408f4 129 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 57 125 1.5E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS10915 4bdacb584bbfe0de6c64043824d4408a 142 Pfam PF14112 Immunity protein 22 5 114 4.7E-22 T 29-03-2018 IPR025560 Immunity protein 22 A616_RS12585 286f71bbd273ffab523e60b3224ea766 218 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 190 2.2E-8 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS12035 d4fe0e6788f38b2e2ca4b924c6748393 230 Gene3D G3DSA:3.40.50.300 17 228 8.4E-41 T 29-03-2018 A616_RS12035 d4fe0e6788f38b2e2ca4b924c6748393 230 SUPERFAMILY SSF52540 19 221 1.66E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12035 d4fe0e6788f38b2e2ca4b924c6748393 230 PIRSF PIRSF000705 4 228 5.8E-61 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 A616_RS12035 d4fe0e6788f38b2e2ca4b924c6748393 230 Pfam PF01712 Deoxynucleoside kinase 21 220 1.2E-58 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain A616_RS04865 18163c61eea7adb8c27ab0ff3e5a261d 307 SUPERFAMILY SSF103481 36 137 7.85E-13 T 29-03-2018 A616_RS04865 18163c61eea7adb8c27ab0ff3e5a261d 307 Pfam PF00892 EamA-like transporter family 6 134 1.0E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS04865 18163c61eea7adb8c27ab0ff3e5a261d 307 Pfam PF00892 EamA-like transporter family 148 287 1.8E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS04865 18163c61eea7adb8c27ab0ff3e5a261d 307 SUPERFAMILY SSF103481 187 290 2.62E-13 T 29-03-2018 A616_RS01205 ce285aa57964f4f7725d900889d811bd 373 SUPERFAMILY SSF53756 2 363 3.37E-27 T 29-03-2018 A616_RS01205 ce285aa57964f4f7725d900889d811bd 373 Gene3D G3DSA:3.40.50.2000 162 362 4.2E-19 T 29-03-2018 A616_RS01205 ce285aa57964f4f7725d900889d811bd 373 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 15 177 5.8E-30 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 A616_RS01205 ce285aa57964f4f7725d900889d811bd 373 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 223 356 1.0E-6 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS13905 3c87277081be34ec0eaee4640acc58df 271 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 38 267 9.5E-71 T 29-03-2018 IPR014231 Sporulation protein YpjB A616_RS27940 af7674d425c96f9c662e0f5bf467705b 185 Pfam PF00857 Isochorismatase family 5 140 2.1E-28 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS27940 af7674d425c96f9c662e0f5bf467705b 185 SUPERFAMILY SSF52499 3 179 6.28E-42 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS27940 af7674d425c96f9c662e0f5bf467705b 185 Gene3D G3DSA:3.40.50.850 2 175 1.7E-35 T 29-03-2018 A616_RS30110 0b91bfdc7f822f6353efe7136d346a95 264 Hamap MF_02077 Lipid II flippase Amj [amj]. 1 261 24.847 T 29-03-2018 IPR021260 Lipid II flippase Amj A616_RS30110 0b91bfdc7f822f6353efe7136d346a95 264 Pfam PF10997 Alternate to MurJ 10 259 1.2E-93 T 29-03-2018 IPR021260 Lipid II flippase Amj A616_RS11830 a8049117a493fc6a4a48e74012991999 474 Gene3D G3DSA:3.40.605.10 2 264 6.7E-89 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A616_RS11830 a8049117a493fc6a4a48e74012991999 474 Gene3D G3DSA:3.40.309.10 265 456 4.3E-59 T 29-03-2018 A616_RS11830 a8049117a493fc6a4a48e74012991999 474 Pfam PF00171 Aldehyde dehydrogenase family 13 470 6.7E-158 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A616_RS11830 a8049117a493fc6a4a48e74012991999 474 SUPERFAMILY SSF53720 4 473 4.71E-148 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A616_RS25665 c312217c8f56c8c44c73a5de94cbbe60 354 SUPERFAMILY SSF56300 44 315 1.14E-43 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS25665 c312217c8f56c8c44c73a5de94cbbe60 354 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 45 282 4.9E-74 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS25665 c312217c8f56c8c44c73a5de94cbbe60 354 Gene3D G3DSA:3.60.21.10 24 347 1.8E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS25665 c312217c8f56c8c44c73a5de94cbbe60 354 SMART SM00854 44 283 3.5E-86 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS30525 9cc3d124f2629618a251d601b4abe584 221 SUPERFAMILY SSF56524 21 205 2.22E-63 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS30525 9cc3d124f2629618a251d601b4abe584 221 Pfam PF00174 Oxidoreductase molybdopterin binding domain 40 186 1.2E-40 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS30525 9cc3d124f2629618a251d601b4abe584 221 Gene3D G3DSA:3.90.420.10 17 210 1.0E-57 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS00025 4309eecee3282dd484e24ce4ceed91fa 95 Pfam PF04025 Domain of unknown function (DUF370) 2 73 4.2E-12 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 A616_RS29640 1b8640c19b0ad36b45857449656e1136 320 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 196 319 1.8E-34 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type A616_RS29640 1b8640c19b0ad36b45857449656e1136 320 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 62 184 6.9E-34 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type A616_RS29640 1b8640c19b0ad36b45857449656e1136 320 Gene3D G3DSA:2.60.40.10 96 166 0.12 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 Gene3D G3DSA:3.40.50.720 141 305 8.3E-20 T 29-03-2018 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 Gene3D G3DSA:3.50.50.60 2 140 3.1E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 192 208 1.0E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 1.0E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 1.0E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.0E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 1.0E-18 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 5.8E-22 T 29-03-2018 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 5.8E-22 T 29-03-2018 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.8E-22 T 29-03-2018 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 5.8E-22 T 29-03-2018 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 5.8E-22 T 29-03-2018 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 279 2.2E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS21175 f0d571e5426483961b868fdca020ce8c 309 SUPERFAMILY SSF51905 5 297 1.73E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS05920 03df68058df997f63cfcfde9c796e797 226 Pfam PF04298 Putative neutral zinc metallopeptidase 8 221 2.9E-86 T 29-03-2018 IPR007395 Putative neutral zinc metallopeptidase A616_RS08135 6820196383d03eeef27deffe3786812c 247 Gene3D G3DSA:2.40.50.40 138 207 5.7E-11 T 29-03-2018 A616_RS08135 6820196383d03eeef27deffe3786812c 247 SMART SM00448 3 114 4.3E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08135 6820196383d03eeef27deffe3786812c 247 SUPERFAMILY SSF52172 4 122 1.71E-26 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS08135 6820196383d03eeef27deffe3786812c 247 Pfam PF00072 Response regulator receiver domain 6 114 2.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS08135 6820196383d03eeef27deffe3786812c 247 Gene3D G3DSA:3.40.50.2300 3 137 8.4E-25 T 29-03-2018 A616_RS08135 6820196383d03eeef27deffe3786812c 247 Pfam PF04397 LytTr DNA-binding domain 147 245 9.0E-23 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS08135 6820196383d03eeef27deffe3786812c 247 SMART SM00850 146 246 1.3E-28 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS08135 6820196383d03eeef27deffe3786812c 247 Gene3D G3DSA:2.20.25.10 208 246 2.1E-15 T 29-03-2018 A616_RS23375 2e88a9a98966c13c182990eef796d94b 423 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 20 369 1.9E-11 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A616_RS23375 2e88a9a98966c13c182990eef796d94b 423 Gene3D G3DSA:2.40.37.10 272 418 2.4E-23 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS23375 2e88a9a98966c13c182990eef796d94b 423 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 29 280 6.5E-33 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A616_RS23375 2e88a9a98966c13c182990eef796d94b 423 SUPERFAMILY SSF51419 17 282 3.49E-50 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS23375 2e88a9a98966c13c182990eef796d94b 423 Gene3D G3DSA:3.20.20.10 24 271 1.1E-44 T 29-03-2018 IPR029066 PLP-binding barrel A616_RS23375 2e88a9a98966c13c182990eef796d94b 423 SUPERFAMILY SSF50621 259 407 1.26E-26 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A616_RS12625 61ad2f81566dfdf38d6d13a2ab55bb3d 407 Gene3D G3DSA:1.20.1250.20 199 393 8.6E-22 T 29-03-2018 A616_RS12625 61ad2f81566dfdf38d6d13a2ab55bb3d 407 Gene3D G3DSA:1.20.1250.20 5 198 2.7E-23 T 29-03-2018 A616_RS12625 61ad2f81566dfdf38d6d13a2ab55bb3d 407 Pfam PF07690 Major Facilitator Superfamily 19 352 7.1E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS12625 61ad2f81566dfdf38d6d13a2ab55bb3d 407 SUPERFAMILY SSF103473 13 391 3.53E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS28825 28cbef729872d521ebbdd776c25106b1 635 Pfam PF13476 AAA domain 24 298 6.2E-7 T 29-03-2018 A616_RS28825 28cbef729872d521ebbdd776c25106b1 635 Gene3D G3DSA:1.10.287.620 374 526 4.0E-5 T 29-03-2018 A616_RS28825 28cbef729872d521ebbdd776c25106b1 635 Gene3D G3DSA:3.40.50.300 5 337 1.8E-8 T 29-03-2018 A616_RS14975 2fec3d3e7004cb84a8d342f00429d5ef 379 SUPERFAMILY SSF53300 215 363 2.91E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS14975 2fec3d3e7004cb84a8d342f00429d5ef 379 SMART SM00327 216 375 1.7E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS14975 2fec3d3e7004cb84a8d342f00429d5ef 379 Pfam PF05762 VWA domain containing CoxE-like protein 161 373 1.6E-43 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like A616_RS14975 2fec3d3e7004cb84a8d342f00429d5ef 379 Gene3D G3DSA:3.40.50.410 177 368 5.5E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS01400 cb3ea2d37cf83d15887d37310896f221 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site A616_RS01400 cb3ea2d37cf83d15887d37310896f221 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 37.784 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01400 cb3ea2d37cf83d15887d37310896f221 209 Pfam PF00297 Ribosomal protein L3 96 179 2.4E-18 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS01400 cb3ea2d37cf83d15887d37310896f221 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 202 1.0E-83 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01400 cb3ea2d37cf83d15887d37310896f221 209 Gene3D G3DSA:4.10.960.10 58 164 1.0E-34 T 29-03-2018 A616_RS01400 cb3ea2d37cf83d15887d37310896f221 209 SUPERFAMILY SSF50447 1 208 2.56E-77 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain A616_RS30905 8189d7443418e713a2a6ad4fff3a565f 115 SUPERFAMILY SSF88659 45 111 2.8E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS30905 8189d7443418e713a2a6ad4fff3a565f 115 Gene3D G3DSA:1.10.10.10 49 115 1.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05185 3c1132b93c0a088b64dce82ae1955161 394 Gene3D G3DSA:1.20.1250.20 1 186 1.6E-33 T 29-03-2018 A616_RS05185 3c1132b93c0a088b64dce82ae1955161 394 Gene3D G3DSA:1.20.1250.20 197 387 3.0E-25 T 29-03-2018 A616_RS05185 3c1132b93c0a088b64dce82ae1955161 394 Pfam PF07690 Major Facilitator Superfamily 216 383 3.0E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05185 3c1132b93c0a088b64dce82ae1955161 394 Pfam PF07690 Major Facilitator Superfamily 9 179 1.0E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05185 3c1132b93c0a088b64dce82ae1955161 394 SUPERFAMILY SSF103473 3 383 3.79E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS31480 abd7511d61af7f98ee917edcb38133fb 202 Pfam PF08241 Methyltransferase domain 30 131 1.4E-22 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS31480 abd7511d61af7f98ee917edcb38133fb 202 Gene3D G3DSA:3.40.50.150 4 183 4.1E-28 T 29-03-2018 A616_RS31480 abd7511d61af7f98ee917edcb38133fb 202 SUPERFAMILY SSF53335 18 138 7.76E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS05120 8a74a527425bdf5a1b59c6ba58188d4a 265 Gene3D G3DSA:3.40.50.10330 1 117 9.5E-26 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A616_RS05120 8a74a527425bdf5a1b59c6ba58188d4a 265 Pfam PF01513 ATP-NAD kinase 40 188 1.1E-26 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A616_RS05120 8a74a527425bdf5a1b59c6ba58188d4a 265 Gene3D G3DSA:2.60.200.30 118 240 6.1E-24 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A616_RS05120 8a74a527425bdf5a1b59c6ba58188d4a 265 Hamap MF_00361 NAD kinase [nadK]. 1 264 23.38 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A616_RS05120 8a74a527425bdf5a1b59c6ba58188d4a 265 SUPERFAMILY SSF111331 31 262 1.19E-60 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A616_RS18050 01bcc274be0799e2fd74777b8240e89a 707 SMART SM00065 134 297 7.8E-15 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS18050 01bcc274be0799e2fd74777b8240e89a 707 Gene3D G3DSA:1.10.10.60 641 681 8.5E-7 T 29-03-2018 A616_RS18050 01bcc274be0799e2fd74777b8240e89a 707 Gene3D G3DSA:3.30.450.40 113 319 4.0E-27 T 29-03-2018 IPR029016 GAF domain-like A616_RS18050 01bcc274be0799e2fd74777b8240e89a 707 Pfam PF13556 PucR C-terminal helix-turn-helix domain 647 702 4.2E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A616_RS18050 01bcc274be0799e2fd74777b8240e89a 707 SUPERFAMILY SSF55781 120 308 4.58E-26 T 29-03-2018 IPR029016 GAF domain-like A616_RS18050 01bcc274be0799e2fd74777b8240e89a 707 Pfam PF13185 GAF domain 137 288 4.2E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 A616_RS27280 67107234bd646764f90664a96df053a8 254 Gene3D G3DSA:3.40.50.1820 26 252 4.2E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS27280 67107234bd646764f90664a96df053a8 254 PIRSF PIRSF017388 19 253 6.6E-50 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 A616_RS27280 67107234bd646764f90664a96df053a8 254 Pfam PF12697 Alpha/beta hydrolase family 36 236 2.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS27280 67107234bd646764f90664a96df053a8 254 SUPERFAMILY SSF53474 34 249 7.67E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS17390 07dac5fb93e942072a6562b7724b6160 423 SUPERFAMILY SSF49373 246 323 6.28E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A616_RS17390 07dac5fb93e942072a6562b7724b6160 423 Pfam PF02368 Bacterial Ig-like domain (group 2) 281 318 4.2E-6 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 A616_RS17390 07dac5fb93e942072a6562b7724b6160 423 Gene3D G3DSA:2.60.40.1080 239 325 3.3E-13 T 29-03-2018 A616_RS24555 9741e9bcd54cc1caf3e5a5902150d751 890 Gene3D G3DSA:3.30.420.40 453 707 6.4E-21 T 29-03-2018 A616_RS24555 9741e9bcd54cc1caf3e5a5902150d751 890 Gene3D G3DSA:3.30.420.40 232 452 1.1E-24 T 29-03-2018 A616_RS24555 9741e9bcd54cc1caf3e5a5902150d751 890 SUPERFAMILY SSF53067 584 701 8.43E-9 T 29-03-2018 A616_RS24555 9741e9bcd54cc1caf3e5a5902150d751 890 SUPERFAMILY SSF53067 444 496 8.43E-9 T 29-03-2018 A616_RS24555 9741e9bcd54cc1caf3e5a5902150d751 890 SUPERFAMILY SSF53067 235 262 2.69E-7 T 29-03-2018 A616_RS24555 9741e9bcd54cc1caf3e5a5902150d751 890 SUPERFAMILY SSF53067 289 428 2.69E-7 T 29-03-2018 A616_RS08885 a66550f37e35046820355e3397c29698 194 Pfam PF02342 TerD domain 4 189 4.1E-80 T 29-03-2018 IPR003325 TerD domain GO:0006950 A616_RS08885 a66550f37e35046820355e3397c29698 194 Gene3D G3DSA:2.60.60.30 19 188 4.4E-61 T 29-03-2018 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 149 5.2E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 20 51 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 Gene3D G3DSA:1.10.1740.10 1 92 6.6E-20 T 29-03-2018 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 Pfam PF04542 Sigma-70 region 2 2 64 5.0E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 SUPERFAMILY SSF88659 75 150 1.48E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 SUPERFAMILY SSF88946 2 67 2.55E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 Pfam PF08281 Sigma-70, region 4 98 145 1.0E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28445 f914b72891d5e234ba5640734fd41697 165 Gene3D G3DSA:1.10.10.10 93 163 9.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04175 224520bb392ca2c5348aad2abd34be5a 67 Pfam PF08863 YolD-like protein 15 63 5.9E-8 T 29-03-2018 IPR014962 YolD-like protein A616_RS32200 371a2d4a55d060fc6d40690a45027ab9 636 Pfam PF01432 Peptidase family M3 238 620 3.2E-69 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A616_RS32200 371a2d4a55d060fc6d40690a45027ab9 636 SUPERFAMILY SSF55486 42 616 1.14E-124 T 29-03-2018 A616_RS32200 371a2d4a55d060fc6d40690a45027ab9 636 Gene3D G3DSA:1.10.1370.10 118 632 1.1E-39 T 29-03-2018 A616_RS32200 371a2d4a55d060fc6d40690a45027ab9 636 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 43 632 6.0E-184 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 A616_RS32200 371a2d4a55d060fc6d40690a45027ab9 636 Pfam PF08439 Oligopeptidase F 150 212 1.0E-19 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain A616_RS25540 5e0f4bf1d36c49cdd21d96c522bd079d 430 Pfam PF01547 Bacterial extracellular solute-binding protein 56 339 5.5E-38 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 A616_RS25540 5e0f4bf1d36c49cdd21d96c522bd079d 430 Gene3D G3DSA:3.40.190.10 30 211 8.2E-43 T 29-03-2018 A616_RS25540 5e0f4bf1d36c49cdd21d96c522bd079d 430 Gene3D G3DSA:3.40.190.10 212 388 4.6E-8 T 29-03-2018 A616_RS25540 5e0f4bf1d36c49cdd21d96c522bd079d 430 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 148 165 - T 29-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 A616_RS25540 5e0f4bf1d36c49cdd21d96c522bd079d 430 SUPERFAMILY SSF53850 19 429 3.11E-69 T 29-03-2018 A616_RS10890 448724a8302f976b9e8bfe413a428fd9 193 PIRSF PIRSF006324 1 193 1.6E-46 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS10890 448724a8302f976b9e8bfe413a428fd9 193 Pfam PF01810 LysE type translocator 2 190 8.8E-33 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS31830 72f591e6e23a47e5bcd63a9d9c007d3e 196 Pfam PF01965 DJ-1/PfpI family 2 177 7.5E-30 T 29-03-2018 IPR002818 DJ-1/PfpI A616_RS31830 72f591e6e23a47e5bcd63a9d9c007d3e 196 Gene3D G3DSA:3.40.50.880 2 194 5.9E-38 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS31830 72f591e6e23a47e5bcd63a9d9c007d3e 196 SUPERFAMILY SSF52317 1 192 2.87E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS21965 5b817020604b5d2af95004862cf66be9 195 Pfam PF11579 Protein of unknown function (DUF3238) 1 194 5.0E-118 T 29-03-2018 IPR021631 Protein of unknown function DUF3238 A616_RS04365 c892800889ea58eaf2b9411e9f793b0a 284 SUPERFAMILY SSF55383 174 257 5.23E-26 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS04365 c892800889ea58eaf2b9411e9f793b0a 284 Pfam PF07833 Copper amine oxidase N-terminal domain 172 263 1.1E-29 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS04365 c892800889ea58eaf2b9411e9f793b0a 284 Gene3D G3DSA:3.30.457.10 245 279 5.2E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS04365 c892800889ea58eaf2b9411e9f793b0a 284 Gene3D G3DSA:3.30.457.10 15 180 2.9E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS04365 c892800889ea58eaf2b9411e9f793b0a 284 Gene3D G3DSA:3.30.457.10 181 244 2.9E-28 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS27865 4223d0b7c3932f9e2552a37c61c05ed7 401 PIRSF PIRSF004810 3 401 3.6E-130 T 29-03-2018 IPR014047 Chromate transporter, long chain A616_RS27865 4223d0b7c3932f9e2552a37c61c05ed7 401 Pfam PF02417 Chromate transporter 21 184 6.3E-32 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A616_RS27865 4223d0b7c3932f9e2552a37c61c05ed7 401 Pfam PF02417 Chromate transporter 235 397 1.0E-40 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A616_RS27865 4223d0b7c3932f9e2552a37c61c05ed7 401 TIGRFAM TIGR00937 2A51: chromate efflux transporter 28 397 3.1E-115 T 29-03-2018 IPR014047 Chromate transporter, long chain A616_RS20710 6d53ab23aaf885a7c8aa3dae6925cefd 27 Pfam PF08183 Stage V sporulation protein family 1 25 6.8E-17 T 29-03-2018 IPR012609 Sporulation stage V, protein M A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 Pfam PF00230 Major intrinsic protein 4 230 8.2E-50 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 230 7.8E-66 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 Gene3D G3DSA:1.20.1080.10 1 241 3.1E-84 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 SUPERFAMILY SSF81338 3 235 6.15E-73 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 PRINTS PR00783 Major intrinsic protein family signature 166 188 2.0E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 PRINTS PR00783 Major intrinsic protein family signature 2 21 2.0E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 PRINTS PR00783 Major intrinsic protein family signature 44 68 2.0E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 PRINTS PR00783 Major intrinsic protein family signature 81 100 2.0E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 PRINTS PR00783 Major intrinsic protein family signature 136 154 2.0E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 PRINTS PR00783 Major intrinsic protein family signature 213 233 2.0E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS27690 f6896994014cdf83e1607c83d1db9e41 276 ProSitePatterns PS00221 MIP family signature. 62 70 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 A616_RS24370 d29c543d3c1b4a25be01d0aec8bd1041 316 SUPERFAMILY SSF103481 46 140 2.62E-11 T 29-03-2018 A616_RS24370 d29c543d3c1b4a25be01d0aec8bd1041 316 Pfam PF00892 EamA-like transporter family 6 139 1.8E-24 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS24370 d29c543d3c1b4a25be01d0aec8bd1041 316 Pfam PF00892 EamA-like transporter family 154 296 1.5E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS24370 d29c543d3c1b4a25be01d0aec8bd1041 316 SUPERFAMILY SSF103481 216 299 4.05E-11 T 29-03-2018 A616_RS25025 b1ddc7a3783505dd71703c828244e233 240 Pfam PF00005 ABC transporter 17 165 1.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS25025 b1ddc7a3783505dd71703c828244e233 240 SUPERFAMILY SSF52540 1 235 1.77E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS25025 b1ddc7a3783505dd71703c828244e233 240 SMART SM00382 26 213 4.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS25025 b1ddc7a3783505dd71703c828244e233 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS25025 b1ddc7a3783505dd71703c828244e233 240 PIRSF PIRSF039085 1 240 3.8E-116 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS25025 b1ddc7a3783505dd71703c828244e233 240 Gene3D G3DSA:3.40.50.300 1 240 1.1E-77 T 29-03-2018 A616_RS23900 771565b227863bc89ecbeaefa10c3f28 70 Pfam PF04328 Selenoprotein, putative 8 70 7.5E-21 T 29-03-2018 IPR007423 Selenoprotein, putative A616_RS17725 b33f5c31b5f945e413eeda7241741204 127 Gene3D G3DSA:1.10.10.10 8 69 4.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17725 b33f5c31b5f945e413eeda7241741204 127 Pfam PF03965 Penicillinase repressor 7 120 7.0E-37 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A616_RS17725 b33f5c31b5f945e413eeda7241741204 127 PIRSF PIRSF019455 1 127 1.4E-39 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A616_RS17725 b33f5c31b5f945e413eeda7241741204 127 SUPERFAMILY SSF46785 5 123 3.66E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17725 b33f5c31b5f945e413eeda7241741204 127 Gene3D G3DSA:1.10.4040.10 72 121 1.6E-14 T 29-03-2018 A616_RS07145 c7e152873edb79da755baaf802f016a0 96 Pfam PF12823 Domain of unknown function (DUF3817) 6 93 9.4E-24 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A616_RS07145 c7e152873edb79da755baaf802f016a0 96 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 4.0E-29 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane A616_RS10255 5109758aeda25583797c0cb96970e5bc 368 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 188 361 2.0E-42 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS10255 5109758aeda25583797c0cb96970e5bc 368 Gene3D G3DSA:2.40.100.10 168 367 3.2E-55 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS10255 5109758aeda25583797c0cb96970e5bc 368 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 200 215 3.5E-15 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS10255 5109758aeda25583797c0cb96970e5bc 368 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 226 238 3.5E-15 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS10255 5109758aeda25583797c0cb96970e5bc 368 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 269 284 3.5E-15 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A616_RS10255 5109758aeda25583797c0cb96970e5bc 368 SUPERFAMILY SSF50891 180 355 1.33E-48 T 29-03-2018 IPR029000 Cyclophilin-like domain A616_RS06730 f3f590652d8c0b5ecf2be93b49b48b5a 185 Pfam PF07336 Putative stress-induced transcription regulator 4 132 2.6E-20 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator A616_RS06730 f3f590652d8c0b5ecf2be93b49b48b5a 185 Pfam PF11706 CGNR zinc finger 138 181 1.9E-18 T 29-03-2018 IPR021005 Zinc finger, CGNR A616_RS06730 f3f590652d8c0b5ecf2be93b49b48b5a 185 Gene3D G3DSA:1.10.3300.10 1 183 1.9E-42 T 29-03-2018 IPR023286 ABATE domain A616_RS06730 f3f590652d8c0b5ecf2be93b49b48b5a 185 SUPERFAMILY SSF160904 3 180 4.05E-42 T 29-03-2018 A616_RS20600 b28944d80cf8a33a87d61fcf814a5035 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 26 153 9.4E-24 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS20600 b28944d80cf8a33a87d61fcf814a5035 159 SUPERFAMILY SSF55961 15 155 7.34E-40 T 29-03-2018 A616_RS20600 b28944d80cf8a33a87d61fcf814a5035 159 Gene3D G3DSA:3.30.530.20 1 159 4.6E-30 T 29-03-2018 IPR023393 START-like domain A616_RS22620 474c1ad254735abdaf8878d23cc4ee8c 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 1.4E-24 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 A616_RS18320 c9987c96c539d83ffc3c7d8b60397ee8 240 Pfam PF07071 KDGP aldolase 5 221 4.3E-78 T 29-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A616_RS18320 c9987c96c539d83ffc3c7d8b60397ee8 240 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 5 236 3.5E-87 T 29-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A616_RS18320 c9987c96c539d83ffc3c7d8b60397ee8 240 Gene3D G3DSA:3.20.20.70 3 240 1.3E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 SUPERFAMILY SSF53850 86 296 1.52E-26 T 29-03-2018 A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 Gene3D G3DSA:3.40.190.10 182 271 1.2E-10 T 29-03-2018 A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 Gene3D G3DSA:1.10.10.10 1 88 2.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 SUPERFAMILY SSF46785 1 87 1.03E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 Pfam PF03466 LysR substrate binding domain 88 281 3.0E-25 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS06625 6aa01ea1bfea96284d824595003a78f7 308 Gene3D G3DSA:3.40.190.10 89 181 1.2E-16 T 29-03-2018 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 Gene3D G3DSA:3.90.226.10 9 312 6.3E-68 T 29-03-2018 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 315 1.5E-152 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.0E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.0E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.0E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.0E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.0E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.0E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 1.7E-67 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 50.272 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A616_RS07945 3fcfae7cb2f998cfde8ebdd973de7913 318 SUPERFAMILY SSF52096 7 315 4.12E-103 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS02450 6e485731bd7b2a146c5490279c2c8f3f 387 Pfam PF00999 Sodium/hydrogen exchanger family 9 372 6.9E-76 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A616_RS02450 6e485731bd7b2a146c5490279c2c8f3f 387 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 10 276 1.4E-72 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 A616_RS02450 6e485731bd7b2a146c5490279c2c8f3f 387 Gene3D G3DSA:1.20.91.10 222 304 8.2E-15 T 29-03-2018 A616_RS22245 7f84f7b0851f610095e4125c55464ccd 362 Pfam PF13487 HD domain 187 248 8.7E-12 T 29-03-2018 A616_RS22245 7f84f7b0851f610095e4125c55464ccd 362 SUPERFAMILY SSF109604 129 296 2.48E-26 T 29-03-2018 A616_RS22245 7f84f7b0851f610095e4125c55464ccd 362 SMART SM00471 131 267 5.6E-5 T 29-03-2018 IPR003607 HD/PDEase domain A616_RS22245 7f84f7b0851f610095e4125c55464ccd 362 Gene3D G3DSA:1.10.3210.10 85 301 5.4E-33 T 29-03-2018 A616_RS14240 63840279ea54eb91df6bc206c749217a 65 Pfam PF11755 Protein of unknown function (DUF3311) 6 61 2.1E-21 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 A616_RS05050 59a9a4012355bcc2b7344a43b0bc318c 98 Gene3D G3DSA:2.60.300.12 6 98 1.2E-8 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS05050 59a9a4012355bcc2b7344a43b0bc318c 98 SUPERFAMILY SSF89360 23 94 2.94E-10 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 SUPERFAMILY SSF111369 61 170 4.05E-11 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 SUPERFAMILY SSF111369 263 385 6.15E-6 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Gene3D G3DSA:2.40.50.100 341 380 0.17 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 370 394 2.0E-8 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 80 100 2.0E-8 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Pfam PF13533 Biotin-lipoyl like 72 112 4.2E-12 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Pfam PF13437 HlyD family secretion protein 133 228 2.5E-7 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 311 412 1.5E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Gene3D G3DSA:2.40.50.100 264 340 1.9E-9 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Gene3D G3DSA:2.40.50.100 133 205 4.8E-4 T 29-03-2018 A616_RS21685 ffc8ba4cd4219280d93a57fa2c4ad87d 505 Gene3D G3DSA:2.40.50.100 69 132 2.4E-13 T 29-03-2018 A616_RS10415 f57b904ae833b591a2c066128e30c84d 332 SUPERFAMILY SSF56112 6 282 3.47E-18 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS10415 f57b904ae833b591a2c066128e30c84d 332 Gene3D G3DSA:3.90.1200.10 98 317 3.3E-10 T 29-03-2018 A616_RS17935 c37488161e13fec098b8a89de9638b48 354 Gene3D G3DSA:1.10.1530.10 6 83 1.1E-26 T 29-03-2018 A616_RS17935 c37488161e13fec098b8a89de9638b48 354 SUPERFAMILY SSF89733 6 346 2.09E-114 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 A616_RS17935 c37488161e13fec098b8a89de9638b48 354 Pfam PF02615 Malate/L-lactate dehydrogenase 8 336 1.5E-123 T 29-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 A616_RS17935 c37488161e13fec098b8a89de9638b48 354 Gene3D G3DSA:3.30.1370.60 84 310 6.9E-88 T 29-03-2018 A616_RS21960 5598eed87f4ed4e3e5fa384aced8f11c 189 Pfam PF13302 Acetyltransferase (GNAT) domain 17 157 1.7E-31 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS21960 5598eed87f4ed4e3e5fa384aced8f11c 189 SUPERFAMILY SSF55729 10 181 1.02E-48 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS21960 5598eed87f4ed4e3e5fa384aced8f11c 189 Gene3D G3DSA:3.40.630.30 2 189 5.3E-31 T 29-03-2018 A616_RS01920 c7745ef2b40fab07856c54c68e787dec 111 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.2E-26 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS01920 c7745ef2b40fab07856c54c68e787dec 111 SUPERFAMILY SSF103481 4 106 3.79E-20 T 29-03-2018 A616_RS14965 5f032162f803f82b8d9bba2e45bddedf 370 Gene3D G3DSA:3.40.50.300 69 220 1.1E-15 T 29-03-2018 A616_RS14965 5f032162f803f82b8d9bba2e45bddedf 370 SUPERFAMILY SSF52540 65 272 7.34E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14965 5f032162f803f82b8d9bba2e45bddedf 370 Pfam PF07728 AAA domain (dynein-related subfamily) 86 225 1.0E-32 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A616_RS14965 5f032162f803f82b8d9bba2e45bddedf 370 Gene3D G3DSA:2.60.300.12 221 298 0.0016 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A616_RS07740 56646b9ec9261634fa287d808a4ea778 427 Gene3D G3DSA:3.40.190.10 194 374 2.0E-9 T 29-03-2018 A616_RS07740 56646b9ec9261634fa287d808a4ea778 427 Gene3D G3DSA:3.40.190.10 27 193 1.5E-40 T 29-03-2018 A616_RS07740 56646b9ec9261634fa287d808a4ea778 427 Pfam PF13416 Bacterial extracellular solute-binding protein 59 363 2.0E-43 T 29-03-2018 A616_RS07740 56646b9ec9261634fa287d808a4ea778 427 SUPERFAMILY SSF53850 21 418 4.05E-81 T 29-03-2018 A616_RS03480 0d028bf97eb3c41dae44ff77bfd2cad2 437 SMART SM00327 135 325 6.2E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03480 0d028bf97eb3c41dae44ff77bfd2cad2 437 SUPERFAMILY SSF53300 132 324 5.09E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03480 0d028bf97eb3c41dae44ff77bfd2cad2 437 Gene3D G3DSA:3.40.50.410 133 434 5.9E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS03480 0d028bf97eb3c41dae44ff77bfd2cad2 437 Pfam PF00092 von Willebrand factor type A domain 138 320 8.9E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS29920 2493297df4dbbfde9017f99992065c3a 167 Pfam PF00430 ATP synthase B/B' CF(0) 13 144 3.4E-32 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A616_RS29920 2493297df4dbbfde9017f99992065c3a 167 SUPERFAMILY SSF81573 70 128 3.66E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A616_RS29920 2493297df4dbbfde9017f99992065c3a 167 Gene3D G3DSA:1.20.5.620 107 131 0.12 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A616_RS29920 2493297df4dbbfde9017f99992065c3a 167 Gene3D G3DSA:1.20.5.620 49 106 2.2E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A616_RS29920 2493297df4dbbfde9017f99992065c3a 167 Hamap MF_01398 ATP synthase subunit b [atpF]. 8 145 12.58 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A616_RS29920 2493297df4dbbfde9017f99992065c3a 167 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 17 163 1.3E-37 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 A616_RS31165 a0cb79739068bb7e361a41f5f75c562c 97 ProDom PD068665 YXCD 1 93 5.0E-23 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD A616_RS31165 a0cb79739068bb7e361a41f5f75c562c 97 Pfam PF10850 Protein of unknown function (DUF2653) 1 88 1.7E-38 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD A616_RS05155 5a18348daeae59eb3f40bb1233c95900 349 Pfam PF03445 Putative nucleotidyltransferase DUF294 38 161 1.5E-30 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 A616_RS05155 5a18348daeae59eb3f40bb1233c95900 349 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 202 340 1.1E-27 T 29-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding A616_RS15235 3480236b141ed84cd2182eed77217fa3 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 266 4.4E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15235 3480236b141ed84cd2182eed77217fa3 275 SUPERFAMILY SSF161098 6 274 1.59E-70 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15235 3480236b141ed84cd2182eed77217fa3 275 Gene3D G3DSA:1.10.3720.10 7 268 8.3E-43 T 29-03-2018 A616_RS24480 50318dbf3a565d9488c5e3f7bf81b9b6 132 Gene3D G3DSA:1.25.10.10 30 127 0.0012 T 29-03-2018 IPR011989 Armadillo-like helical A616_RS03460 81d2b043aea97dda5b4543236d4c0b97 133 Pfam PF07811 TadE-like protein 12 53 1.8E-6 T 29-03-2018 IPR012495 TadE-like A616_RS09010 08020e3f4155632f99b6473e042d26ee 183 Gene3D G3DSA:2.130.10.130 20 177 7.5E-8 T 29-03-2018 A616_RS09010 08020e3f4155632f99b6473e042d26ee 183 SUPERFAMILY SSF69318 58 158 1.7E-6 T 29-03-2018 A616_RS21860 b584e63b7410358587a0e48f59e2f46c 341 Gene3D G3DSA:1.10.3470.10 9 341 4.4E-71 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS21860 b584e63b7410358587a0e48f59e2f46c 341 Pfam PF01032 FecCD transport family 24 338 8.6E-93 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS21860 b584e63b7410358587a0e48f59e2f46c 341 SUPERFAMILY SSF81345 6 338 7.72E-84 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS27525 52042048eefacfb3cc5d8a150a0195ca 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 11 123 2.9E-21 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 A616_RS27525 52042048eefacfb3cc5d8a150a0195ca 133 SUPERFAMILY SSF54637 6 124 3.05E-32 T 29-03-2018 IPR029069 HotDog domain A616_RS27525 52042048eefacfb3cc5d8a150a0195ca 133 Pfam PF03061 Thioesterase superfamily 41 114 1.8E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS27525 52042048eefacfb3cc5d8a150a0195ca 133 Gene3D G3DSA:3.10.129.10 2 125 1.4E-31 T 29-03-2018 A616_RS06690 4122061f6d729b781b054686d21228e9 166 Pfam PF01037 Lrp/AsnC ligand binding domain 71 145 1.7E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A616_RS06690 4122061f6d729b781b054686d21228e9 166 Gene3D G3DSA:1.10.10.10 1 53 6.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06690 4122061f6d729b781b054686d21228e9 166 Gene3D G3DSA:3.30.70.920 54 152 1.1E-22 T 29-03-2018 A616_RS06690 4122061f6d729b781b054686d21228e9 166 SMART SM00344 1 116 4.6E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A616_RS06690 4122061f6d729b781b054686d21228e9 166 SUPERFAMILY SSF54909 66 147 4.16E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS28200 887ac1026d9453d328277668e25824d7 339 Pfam PF13407 Periplasmic binding protein domain 44 301 5.6E-38 T 29-03-2018 IPR025997 Periplasmic binding protein A616_RS28200 887ac1026d9453d328277668e25824d7 339 Gene3D G3DSA:3.40.50.2300 41 170 5.3E-20 T 29-03-2018 A616_RS28200 887ac1026d9453d328277668e25824d7 339 Gene3D G3DSA:3.40.50.2300 176 311 2.9E-20 T 29-03-2018 A616_RS28200 887ac1026d9453d328277668e25824d7 339 SUPERFAMILY SSF53822 42 319 1.05E-53 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS25705 4020471bab5cd2f99a0d136e43ad6e53 340 SUPERFAMILY SSF53850 115 299 2.61E-6 T 29-03-2018 A616_RS25705 4020471bab5cd2f99a0d136e43ad6e53 340 PIRSF PIRSF017082 7 340 4.0E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A616_RS25705 4020471bab5cd2f99a0d136e43ad6e53 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 336 1.5E-45 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A616_RS25705 4020471bab5cd2f99a0d136e43ad6e53 340 Gene3D G3DSA:3.40.190.10 138 266 1.2E-6 T 29-03-2018 A616_RS17215 3025ec8546ebce436e4237c0cb9f17ce 533 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 100 106 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A616_RS17215 3025ec8546ebce436e4237c0cb9f17ce 533 SUPERFAMILY SSF53335 8 224 4.85E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS17215 3025ec8546ebce436e4237c0cb9f17ce 533 Pfam PF13708 Domain of unknown function (DUF4942) 277 478 5.8E-37 T 29-03-2018 IPR031339 Domain of unknown function DUF4942 A616_RS17215 3025ec8546ebce436e4237c0cb9f17ce 533 Gene3D G3DSA:3.40.50.150 7 232 4.1E-16 T 29-03-2018 A616_RS26165 b3c3b07b271afea3f1d04cbc8bd330e9 273 Pfam PF10978 Protein of unknown function (DUF2785) 75 245 5.6E-52 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 A616_RS27950 0382711d221ea161a167eed1031e5eea 67 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 62 3.8E-35 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 A616_RS27950 0382711d221ea161a167eed1031e5eea 67 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 1.6E-33 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 A616_RS26525 bbcf3d6f937b5dbde76551cc7092a78a 500 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 35 485 9.6E-152 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS26525 bbcf3d6f937b5dbde76551cc7092a78a 500 PIRSF PIRSF005690 22 498 2.3E-139 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS31380 102cdfd9a3932234184f4d811334a113 262 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 234 7.8E-41 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A616_RS31380 102cdfd9a3932234184f4d811334a113 262 SUPERFAMILY SSF56784 6 256 7.6E-62 T 29-03-2018 IPR023214 HAD-like domain A616_RS31380 102cdfd9a3932234184f4d811334a113 262 Gene3D G3DSA:3.40.50.1000 1 261 4.4E-36 T 29-03-2018 IPR023214 HAD-like domain A616_RS31380 102cdfd9a3932234184f4d811334a113 262 Pfam PF13242 HAD-hyrolase-like 185 255 3.6E-20 T 29-03-2018 A616_RS31380 102cdfd9a3932234184f4d811334a113 262 PIRSF PIRSF000915 4 261 2.6E-59 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A616_RS31380 102cdfd9a3932234184f4d811334a113 262 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 109 2.3E-24 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 Gene3D G3DSA:3.40.50.1820 3 349 8.7E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 2.3E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.3E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.3E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 Pfam PF12697 Alpha/beta hydrolase family 30 341 1.2E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 SUPERFAMILY SSF53474 305 345 2.34E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS06550 ea3a2ad7b95e5d3b52e777bb7df037eb 349 SUPERFAMILY SSF53474 3 270 2.34E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 Pfam PF00491 Arginase family 4 292 8.7E-81 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 PIRSF PIRSF036979 1 294 1.4E-38 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 Gene3D G3DSA:3.40.800.10 1 294 7.7E-93 T 29-03-2018 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 ProSitePatterns PS01053 Arginase family signature. 223 244 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 PRINTS PR00116 Arginase signature 171 189 7.3E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 PRINTS PR00116 Arginase signature 94 109 7.3E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 PRINTS PR00116 Arginase signature 117 144 7.3E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 PRINTS PR00116 Arginase signature 220 249 7.3E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 PRINTS PR00116 Arginase signature 255 269 7.3E-43 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 TIGRFAM TIGR01229 rocF_arginase: arginase 6 297 6.4E-103 T 29-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 A616_RS01685 0b6b547ab9d007732c101157f5fece94 298 SUPERFAMILY SSF52768 4 294 1.13E-96 T 29-03-2018 A616_RS14625 b2f1b50c615526a9939f265e16d478c6 284 SUPERFAMILY SSF103481 40 134 1.7E-12 T 29-03-2018 A616_RS14625 b2f1b50c615526a9939f265e16d478c6 284 Pfam PF00892 EamA-like transporter family 4 134 6.1E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS14625 b2f1b50c615526a9939f265e16d478c6 284 Pfam PF00892 EamA-like transporter family 153 280 3.5E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS14625 b2f1b50c615526a9939f265e16d478c6 284 SUPERFAMILY SSF103481 191 282 7.32E-11 T 29-03-2018 A616_RS30750 f6713461b26ee78cbc9dcfb2e0df7e5a 258 Pfam PF06130 Phosphate propanoyltransferase 175 239 1.1E-14 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 A616_RS30750 f6713461b26ee78cbc9dcfb2e0df7e5a 258 Pfam PF06130 Phosphate propanoyltransferase 66 145 1.0E-30 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 A616_RS30750 f6713461b26ee78cbc9dcfb2e0df7e5a 258 Gene3D G3DSA:2.40.40.20 68 257 0.0012 T 29-03-2018 A616_RS30750 f6713461b26ee78cbc9dcfb2e0df7e5a 258 PIRSF PIRSF010130 41 252 1.2E-86 T 29-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 A616_RS30295 e896b90c8b2be73be6bb240b892ae0cc 242 Pfam PF04519 Polymer-forming cytoskeletal 10 82 2.4E-6 T 29-03-2018 IPR007607 Protein of unknown function DUF583 A616_RS13445 bb1ce520ac724ab362c4f0476bfd8d8d 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 28 479 5.7E-151 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS13445 bb1ce520ac724ab362c4f0476bfd8d8d 489 PIRSF PIRSF005690 6 489 2.2E-130 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS00450 5e4b69dcb2cc4d7434ed30d2df276822 262 Pfam PF01925 Sulfite exporter TauE/SafE 11 256 2.2E-38 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A616_RS08430 6509b955c1c87073747b21e81f9099f8 127 Pfam PF13564 DoxX-like family 15 113 1.2E-15 T 29-03-2018 IPR032808 DoxX family A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 Gene3D G3DSA:2.40.50.100 46 144 1.5E-11 T 29-03-2018 A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 SUPERFAMILY SSF111369 47 138 1.44E-9 T 29-03-2018 A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 Pfam PF13533 Biotin-lipoyl like 48 93 4.8E-9 T 29-03-2018 A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 Gene3D G3DSA:1.20.1600.10 208 395 3.1E-11 T 29-03-2018 A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 Pfam PF13437 HlyD family secretion protein 273 358 5.1E-12 T 29-03-2018 A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 Gene3D G3DSA:1.10.287.470 146 205 5.3E-8 T 29-03-2018 A616_RS11870 cf3d7cb0e68b759191f11000465271e9 396 SUPERFAMILY SSF111369 213 333 6.02E-12 T 29-03-2018 A616_RS14720 7a7e265435127afb22e399c7c43f62a1 109 SUPERFAMILY SSF46767 1 85 4.19E-22 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS14720 7a7e265435127afb22e399c7c43f62a1 109 Gene3D G3DSA:1.10.10.10 1 108 1.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS14720 7a7e265435127afb22e399c7c43f62a1 109 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 3 84 3.1E-22 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A616_RS15280 d401b61f77451608cb7434a1af26a0a0 196 SUPERFAMILY SSF52218 1 191 2.64E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS15280 d401b61f77451608cb7434a1af26a0a0 196 Gene3D G3DSA:3.40.50.360 1 194 1.1E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS15280 d401b61f77451608cb7434a1af26a0a0 196 Pfam PF02525 Flavodoxin-like fold 1 181 4.7E-44 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS05000 37a97049d3410e639863626b26fc9ff2 269 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 58 9.1E-21 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain A616_RS05000 37a97049d3410e639863626b26fc9ff2 269 Pfam PF00691 OmpA family 150 249 1.5E-18 T 29-03-2018 IPR006665 OmpA-like domain A616_RS05000 37a97049d3410e639863626b26fc9ff2 269 SUPERFAMILY SSF103088 137 255 1.06E-30 T 29-03-2018 IPR006665 OmpA-like domain A616_RS05000 37a97049d3410e639863626b26fc9ff2 269 Gene3D G3DSA:3.30.1330.60 77 268 1.8E-41 T 29-03-2018 IPR006665 OmpA-like domain A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 SUPERFAMILY SSF53822 36 379 4.04E-89 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 Gene3D G3DSA:3.40.50.2300 208 365 9.4E-20 T 29-03-2018 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 Gene3D G3DSA:3.40.50.2300 19 207 9.3E-41 T 29-03-2018 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 37 53 3.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 78 96 3.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 265 283 3.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 99 109 3.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 59 75 3.6E-10 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS25225 cc6cc497dc7a426bc507fed23272325a 381 Pfam PF13458 Periplasmic binding protein 37 376 1.4E-66 T 29-03-2018 IPR028081 Leucine-binding protein domain A616_RS25900 42b70f34d5172a34ebf64379e31cddfd 328 SUPERFAMILY SSF81345 3 322 1.23E-87 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS25900 42b70f34d5172a34ebf64379e31cddfd 328 Pfam PF01032 FecCD transport family 14 321 3.1E-99 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS25900 42b70f34d5172a34ebf64379e31cddfd 328 Gene3D G3DSA:1.10.3470.10 1 328 3.7E-78 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS27015 7eb17b8237ff0b1b3babdc1eb0b2758d 268 Gene3D G3DSA:3.40.50.300 1 166 5.4E-14 T 29-03-2018 A616_RS27015 7eb17b8237ff0b1b3babdc1eb0b2758d 268 SUPERFAMILY SSF52540 2 153 4.25E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS05880 3317d79810afaf8f8b668e702b61cbb9 122 Pfam PF14107 Domain of unknown function (DUF4280) 20 121 3.9E-29 T 29-03-2018 IPR025460 Protein of unknown function DUF4280 A616_RS15780 a5f50688f85ba8be4fa84ae4b64f3c03 79 Pfam PF13192 Thioredoxin domain 7 66 7.4E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS15780 a5f50688f85ba8be4fa84ae4b64f3c03 79 Gene3D G3DSA:3.40.30.10 4 79 7.6E-11 T 29-03-2018 A616_RS15780 a5f50688f85ba8be4fa84ae4b64f3c03 79 SUPERFAMILY SSF52833 2 77 4.28E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS30655 03a16992edbe06bd5c354a205b5e0844 486 Gene3D G3DSA:2.60.40.1630 72 214 1.5E-18 T 29-03-2018 A616_RS30655 03a16992edbe06bd5c354a205b5e0844 486 Gene3D G3DSA:2.60.40.1640 219 399 6.8E-12 T 29-03-2018 A616_RS30655 03a16992edbe06bd5c354a205b5e0844 486 Pfam PF13786 Domain of unknown function (DUF4179) 42 128 2.6E-15 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS29005 992c84fc4c673cf17db078eb6303e15f 336 Gene3D G3DSA:3.40.50.1980 174 333 1.1E-34 T 29-03-2018 A616_RS29005 992c84fc4c673cf17db078eb6303e15f 336 SUPERFAMILY SSF53807 59 329 1.96E-72 T 29-03-2018 A616_RS29005 992c84fc4c673cf17db078eb6303e15f 336 Gene3D G3DSA:3.40.50.1980 44 173 3.8E-31 T 29-03-2018 A616_RS29005 992c84fc4c673cf17db078eb6303e15f 336 Pfam PF01497 Periplasmic binding protein 76 310 2.6E-35 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS12065 2b4b1b8e5addc70756539c53c25a07e5 254 Pfam PF11307 Protein of unknown function (DUF3109) 37 168 2.1E-9 T 29-03-2018 IPR021458 Protein of unknown function DUF3109 A616_RS11155 ec35a94b2c88a8152fd08021ea8259de 270 SUPERFAMILY SSF56601 5 265 9.09E-50 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS11155 ec35a94b2c88a8152fd08021ea8259de 270 Pfam PF13354 Beta-lactamase enzyme family 27 239 3.2E-57 T 29-03-2018 A616_RS11155 ec35a94b2c88a8152fd08021ea8259de 270 Gene3D G3DSA:3.40.710.10 2 270 5.1E-33 T 29-03-2018 A616_RS05025 997a0ea9b96ae76d405fa4a2e68716fe 117 Pfam PF00893 Small Multidrug Resistance protein 4 92 8.9E-20 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS05025 997a0ea9b96ae76d405fa4a2e68716fe 117 SUPERFAMILY SSF103481 7 101 3.01E-14 T 29-03-2018 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 Pfam PF00067 Cytochrome P450 7 437 2.4E-94 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 386 395 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00463 E-class P450 group I signature 32 51 1.5E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00463 E-class P450 group I signature 383 393 1.5E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00463 E-class P450 group I signature 246 263 1.5E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00463 E-class P450 group I signature 266 292 1.5E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00463 E-class P450 group I signature 393 416 1.5E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00463 E-class P450 group I signature 348 372 1.5E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00385 P450 superfamily signature 309 320 3.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00385 P450 superfamily signature 384 393 3.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00385 P450 superfamily signature 257 274 3.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 PRINTS PR00385 P450 superfamily signature 393 404 3.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 SUPERFAMILY SSF48264 5 446 1.57E-119 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 A616_RS05670 724d8c8b058910ab400a208ff0ecbbd8 446 Gene3D G3DSA:1.10.630.10 3 446 5.0E-131 T 29-03-2018 A616_RS10080 80649c65fe215e442e98b4d29275d5a2 259 Pfam PF00483 Nucleotidyl transferase 2 214 5.4E-20 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A616_RS10080 80649c65fe215e442e98b4d29275d5a2 259 SUPERFAMILY SSF53448 1 254 1.49E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10080 80649c65fe215e442e98b4d29275d5a2 259 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 255 2.0E-127 T 29-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 A616_RS10080 80649c65fe215e442e98b4d29275d5a2 259 Gene3D G3DSA:3.90.550.10 1 257 2.3E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS27360 03db8d93bb676664759c9e02483b5a94 155 Gene3D G3DSA:1.20.120.450 1 155 2.5E-31 T 29-03-2018 A616_RS27360 03db8d93bb676664759c9e02483b5a94 155 Pfam PF05163 DinB family 3 146 2.4E-33 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB A616_RS27360 03db8d93bb676664759c9e02483b5a94 155 SUPERFAMILY SSF109854 1 136 1.83E-35 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS02885 f40d59f51591a779ce3af9118a47ee1f 99 Pfam PF01402 Ribbon-helix-helix protein, copG family 15 52 2.9E-5 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A616_RS02885 f40d59f51591a779ce3af9118a47ee1f 99 SUPERFAMILY SSF47598 12 55 1.85E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 A616_RS02885 f40d59f51591a779ce3af9118a47ee1f 99 Gene3D G3DSA:1.10.1220.10 14 64 8.4E-15 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 Gene3D G3DSA:3.40.50.720 2 75 2.3E-7 T 29-03-2018 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 Gene3D G3DSA:3.40.50.720 76 198 3.3E-28 T 29-03-2018 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 SUPERFAMILY SSF51735 3 200 1.8E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 2.7E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 PRINTS PR00084 Mannitol dehydrogenase signature 150 163 2.7E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.7E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 PRINTS PR00084 Mannitol dehydrogenase signature 168 183 2.7E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 376 38.95 T 29-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 148 345 3.4E-53 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 Gene3D G3DSA:1.10.1040.10 201 383 1.2E-42 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 SUPERFAMILY SSF48179 202 382 9.52E-44 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 150 162 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 A616_RS30815 0d5c19ba4d74b84d6c211dd659a99bf6 386 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 123 3.0E-24 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 A616_RS15150 f6d1c9d918c65a78cebcfa570e58f904 421 Gene3D G3DSA:3.40.50.150 234 418 9.2E-24 T 29-03-2018 A616_RS15150 f6d1c9d918c65a78cebcfa570e58f904 421 Pfam PF13649 Methyltransferase domain 252 344 1.1E-10 T 29-03-2018 A616_RS15150 f6d1c9d918c65a78cebcfa570e58f904 421 SUPERFAMILY SSF53335 222 398 1.13E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS24275 d74b81cc675a299ec7e9ba3021cbfbad 367 Gene3D G3DSA:2.40.10.10 210 312 6.7E-7 T 29-03-2018 A616_RS24275 d74b81cc675a299ec7e9ba3021cbfbad 367 SUPERFAMILY SSF50494 113 296 1.57E-8 T 29-03-2018 IPR009003 Peptidase S1, PA clan A616_RS15505 32f2df584e57edb71c8e858386fe50fb 144 Gene3D G3DSA:3.30.530.20 1 144 1.4E-27 T 29-03-2018 IPR023393 START-like domain A616_RS15505 32f2df584e57edb71c8e858386fe50fb 144 SUPERFAMILY SSF55961 6 144 3.08E-41 T 29-03-2018 A616_RS15505 32f2df584e57edb71c8e858386fe50fb 144 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 143 2.2E-14 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS31695 dd09724dfa869ad073b67c35c78f95db 393 Pfam PF02687 FtsX-like permease family 299 386 3.2E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS31695 dd09724dfa869ad073b67c35c78f95db 393 Pfam PF12704 MacB-like periplasmic core domain 22 236 4.4E-36 T 29-03-2018 IPR025857 MacB-like periplasmic core domain A616_RS03420 f9538eac9fa7176050ccf37cdf6522a3 462 Pfam PF00437 Type II/IV secretion system protein 102 378 6.7E-83 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A616_RS03420 f9538eac9fa7176050ccf37cdf6522a3 462 Gene3D G3DSA:3.40.50.300 204 411 3.3E-17 T 29-03-2018 A616_RS03420 f9538eac9fa7176050ccf37cdf6522a3 462 SUPERFAMILY SSF52540 81 384 3.1E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03420 f9538eac9fa7176050ccf37cdf6522a3 462 Gene3D G3DSA:3.30.450.90 97 201 3.2E-38 T 29-03-2018 A616_RS13080 03b2de9f1cef081b9b0f639564d8038e 231 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 39 230 1.1E-55 T 29-03-2018 IPR014195 Sporulation stage III, protein AG A616_RS28385 cca1839bf6e1e0278b400111ad3fca04 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.1E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28385 cca1839bf6e1e0278b400111ad3fca04 311 SUPERFAMILY SSF161098 91 292 1.42E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28385 cca1839bf6e1e0278b400111ad3fca04 311 Gene3D G3DSA:1.10.3720.10 1 293 2.1E-50 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.20.120.330 10 194 3.2E-6 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 SUPERFAMILY SSF57997 707 928 9.81E-8 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.20.5.50 219 394 0.11 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 SUPERFAMILY SSF57997 1114 1390 7.85E-10 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 1343 1492 0.046 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 907 1048 1.7E-6 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 761 906 9.2E-7 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 607 760 3.3E-6 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 1049 1187 2.6E-6 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 1188 1342 2.4E-5 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 Gene3D G3DSA:1.10.287.620 1805 1951 1.2E-4 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 SUPERFAMILY SSF57997 896 1146 7.85E-11 T 29-03-2018 A616_RS10025 d4545b849b0b4cfc27d1ab5eeea5dc44 1998 SUPERFAMILY SSF57997 518 765 1.31E-5 T 29-03-2018 A616_RS15490 e803ac12085482674ae2879a77ce8034 451 Gene3D G3DSA:3.40.630.10 6 197 3.2E-30 T 29-03-2018 A616_RS15490 e803ac12085482674ae2879a77ce8034 451 Pfam PF01546 Peptidase family M20/M25/M40 80 444 3.8E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A616_RS15490 e803ac12085482674ae2879a77ce8034 451 Pfam PF07687 Peptidase dimerisation domain 192 349 1.1E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain A616_RS15490 e803ac12085482674ae2879a77ce8034 451 SUPERFAMILY SSF53187 361 447 9.71E-50 T 29-03-2018 A616_RS15490 e803ac12085482674ae2879a77ce8034 451 SUPERFAMILY SSF53187 12 194 9.71E-50 T 29-03-2018 A616_RS15490 e803ac12085482674ae2879a77ce8034 451 Gene3D G3DSA:3.30.70.360 198 366 8.2E-43 T 29-03-2018 A616_RS00315 3a8558df48f407131ee0bbdf5a4c0a1f 135 Gene3D G3DSA:3.30.1330.40 3 134 2.3E-34 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS00315 3a8558df48f407131ee0bbdf5a4c0a1f 135 SUPERFAMILY SSF55298 8 133 1.23E-35 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS00315 3a8558df48f407131ee0bbdf5a4c0a1f 135 Pfam PF01042 Endoribonuclease L-PSP 17 132 3.9E-32 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family A616_RS03735 f0b3354113cd1a7f1ab60248cfb5a49d 1527 Gene3D G3DSA:2.60.120.260 516 600 0.0014 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS03735 f0b3354113cd1a7f1ab60248cfb5a49d 1527 Gene3D G3DSA:2.60.120.380 210 298 0.17 T 29-03-2018 A616_RS05180 a5ec67d4ce38c623407beddda974d445 415 Pfam PF07690 Major Facilitator Superfamily 16 366 8.1E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS05180 a5ec67d4ce38c623407beddda974d445 415 Gene3D G3DSA:1.20.1250.20 215 415 5.1E-12 T 29-03-2018 A616_RS05180 a5ec67d4ce38c623407beddda974d445 415 SUPERFAMILY SSF103473 10 407 1.07E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS05180 a5ec67d4ce38c623407beddda974d445 415 Gene3D G3DSA:1.20.1250.20 1 202 8.7E-18 T 29-03-2018 A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 Gene3D G3DSA:3.90.120.10 259 498 4.3E-6 T 29-03-2018 A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 Gene3D G3DSA:3.40.50.150 7 233 6.1E-44 T 29-03-2018 A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 SUPERFAMILY SSF53335 171 261 2.27E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 SUPERFAMILY SSF53335 413 508 2.27E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 SUPERFAMILY SSF53335 8 128 2.27E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 Pfam PF00145 C-5 cytosine-specific DNA methylase 9 124 1.4E-5 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS06260 23f9bfc10e45e2bfb930c2ad49a8976d 538 Pfam PF00145 C-5 cytosine-specific DNA methylase 167 508 5.9E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS00530 0b07098adeede4348fc12d3191ff2a14 325 Pfam PF02517 CAAX protease self-immunity 232 317 6.9E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A616_RS04440 8c7abd187283dad5cbb7a4a720e1857e 327 Gene3D G3DSA:3.40.50.720 1 325 3.0E-63 T 29-03-2018 A616_RS04440 8c7abd187283dad5cbb7a4a720e1857e 327 SUPERFAMILY SSF51735 1 259 1.8E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS04440 8c7abd187283dad5cbb7a4a720e1857e 327 Pfam PF02719 Polysaccharide biosynthesis protein 6 278 3.6E-94 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A616_RS06230 caf52d90bec3bba58bcbb43c01392cae 289 Pfam PF01695 IstB-like ATP binding protein 122 261 4.2E-17 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A616_RS06230 caf52d90bec3bba58bcbb43c01392cae 289 Gene3D G3DSA:3.40.50.300 89 264 8.0E-10 T 29-03-2018 A616_RS06230 caf52d90bec3bba58bcbb43c01392cae 289 SMART SM00382 129 274 0.0096 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS06230 caf52d90bec3bba58bcbb43c01392cae 289 SUPERFAMILY SSF52540 92 251 1.51E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14490 07dc97b89573ef6cf37686d8649bdd94 112 Gene3D G3DSA:3.30.428.10 1 108 3.6E-34 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS14490 07dc97b89573ef6cf37686d8649bdd94 112 SUPERFAMILY SSF54197 1 111 1.19E-38 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS14490 07dc97b89573ef6cf37686d8649bdd94 112 Pfam PF01230 HIT domain 11 107 6.5E-27 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS14490 07dc97b89573ef6cf37686d8649bdd94 112 PRINTS PR00332 Histidine triad family signature 25 43 4.7E-20 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS14490 07dc97b89573ef6cf37686d8649bdd94 112 PRINTS PR00332 Histidine triad family signature 4 20 4.7E-20 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS14490 07dc97b89573ef6cf37686d8649bdd94 112 PRINTS PR00332 Histidine triad family signature 93 103 4.7E-20 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS13245 67260199aad89ec782c84d1e09cd6228 230 Gene3D G3DSA:3.90.550.10 1 230 1.1E-34 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS13245 67260199aad89ec782c84d1e09cd6228 230 Pfam PF00535 Glycosyl transferase family 2 5 119 2.3E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS13245 67260199aad89ec782c84d1e09cd6228 230 SUPERFAMILY SSF53448 2 204 1.72E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS25725 e79de1de75202a1609021a98f056c16f 427 Gene3D G3DSA:1.25.40.10 281 391 9.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25725 e79de1de75202a1609021a98f056c16f 427 SUPERFAMILY SSF47413 7 66 1.3E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS25725 e79de1de75202a1609021a98f056c16f 427 Gene3D G3DSA:1.10.260.40 3 133 7.1E-13 T 29-03-2018 A616_RS25725 e79de1de75202a1609021a98f056c16f 427 SMART SM00530 11 67 4.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS25725 e79de1de75202a1609021a98f056c16f 427 SUPERFAMILY SSF48452 194 318 4.17E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25725 e79de1de75202a1609021a98f056c16f 427 Gene3D G3DSA:1.25.40.10 188 280 3.8E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS25725 e79de1de75202a1609021a98f056c16f 427 Pfam PF01381 Helix-turn-helix 12 64 1.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS09560 ed316d4852754b7723e68679b09b5983 78 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 4 71 19.598 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A616_RS09560 ed316d4852754b7723e68679b09b5983 78 Pfam PF14098 Small, acid-soluble spore protein I 6 70 2.4E-26 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A616_RS09560 ed316d4852754b7723e68679b09b5983 78 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 7 68 6.0E-23 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 A616_RS01215 7548b3844e9e39d11554d7994f0d7cf1 154 PIRSF PIRSF010607 1 154 3.4E-58 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 A616_RS01215 7548b3844e9e39d11554d7994f0d7cf1 154 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 7.8E-55 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 A616_RS18400 c3b5077a1369a9756a47605bb07fbbdd 115 Gene3D G3DSA:3.20.20.360 15 114 5.8E-22 T 29-03-2018 A616_RS18400 c3b5077a1369a9756a47605bb07fbbdd 115 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 95 110 4.7E-8 T 29-03-2018 A616_RS18400 c3b5077a1369a9756a47605bb07fbbdd 115 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 78 93 4.7E-8 T 29-03-2018 A616_RS18400 c3b5077a1369a9756a47605bb07fbbdd 115 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 18 108 7.2E-28 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A616_RS18400 c3b5077a1369a9756a47605bb07fbbdd 115 SUPERFAMILY SSF51621 17 110 2.74E-25 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS18795 61bd53c271850118da8503156a690aaa 155 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 112 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site A616_RS18795 61bd53c271850118da8503156a690aaa 155 SUPERFAMILY SSF46785 46 151 1.72E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18795 61bd53c271850118da8503156a690aaa 155 SMART SM00347 39 142 1.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS18795 61bd53c271850118da8503156a690aaa 155 Gene3D G3DSA:1.10.10.10 11 155 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18795 61bd53c271850118da8503156a690aaa 155 Pfam PF01047 MarR family 46 104 3.8E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS14945 3b4af7e5989d0cc2711f494d4d9e104c 280 SMART SM00382 32 213 3.4E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14945 3b4af7e5989d0cc2711f494d4d9e104c 280 Gene3D G3DSA:3.40.50.300 1 258 9.5E-66 T 29-03-2018 A616_RS14945 3b4af7e5989d0cc2711f494d4d9e104c 280 SUPERFAMILY SSF52540 3 212 7.72E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS14945 3b4af7e5989d0cc2711f494d4d9e104c 280 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS14945 3b4af7e5989d0cc2711f494d4d9e104c 280 Pfam PF00005 ABC transporter 23 162 1.3E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02675 2cb25bbdc5464ea1d1a6052ddc91472a 483 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 7 459 6.0E-156 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS02675 2cb25bbdc5464ea1d1a6052ddc91472a 483 PIRSF PIRSF005690 2 475 3.2E-143 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS27870 0bd5b61f7f8aa8a1745f12dba5a3b7ab 599 Pfam PF13203 Putative metallopeptidase domain 211 450 1.2E-18 T 29-03-2018 IPR025154 Putative metallopeptidase domain A616_RS27870 0bd5b61f7f8aa8a1745f12dba5a3b7ab 599 Gene3D G3DSA:3.30.2010.10 137 292 7.4E-4 T 29-03-2018 A616_RS27870 0bd5b61f7f8aa8a1745f12dba5a3b7ab 599 Pfam PF09967 VWA-like domain (DUF2201) 475 552 3.1E-6 T 29-03-2018 IPR018698 VWA-like domain A616_RS01410 b4c38b6433e2fa864439967dc75c6983 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 22.109 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A616_RS01410 b4c38b6433e2fa864439967dc75c6983 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A616_RS01410 b4c38b6433e2fa864439967dc75c6983 96 Pfam PF00276 Ribosomal protein L23 6 88 2.5E-33 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A616_RS01410 b4c38b6433e2fa864439967dc75c6983 96 Gene3D G3DSA:3.30.70.330 2 96 8.5E-32 T 29-03-2018 A616_RS01410 b4c38b6433e2fa864439967dc75c6983 96 SUPERFAMILY SSF54189 2 93 3.35E-31 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS16405 d191bfef3c60e4e74ff818320061c026 219 SUPERFAMILY SSF52980 93 183 3.04E-5 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A616_RS16405 d191bfef3c60e4e74ff818320061c026 219 Gene3D G3DSA:3.40.1350.10 17 183 4.1E-32 T 29-03-2018 A616_RS20010 7d715934a40b5d164d6d9bfcf639b1b1 407 Pfam PF02120 Flagellar hook-length control protein FliK 270 349 5.1E-20 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal A616_RS20010 7d715934a40b5d164d6d9bfcf639b1b1 407 Gene3D G3DSA:1.10.1420.10 57 406 0.0012 T 29-03-2018 A616_RS21660 2604bb8773601c4ac01f40a42ae63716 284 Pfam PF12787 EcsC protein family 14 264 1.1E-76 T 29-03-2018 IPR024787 EcsC protein A616_RS21660 2604bb8773601c4ac01f40a42ae63716 284 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 15 257 4.0E-73 T 29-03-2018 A616_RS00745 e1f2dc8c4171020127c73d3cac9b63ae 94 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 10 94 5.0E-27 T 29-03-2018 IPR012504 Sporulation protein YabP A616_RS00745 e1f2dc8c4171020127c73d3cac9b63ae 94 PIRSF PIRSF011576 1 94 5.6E-39 T 29-03-2018 IPR012504 Sporulation protein YabP A616_RS00745 e1f2dc8c4171020127c73d3cac9b63ae 94 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 10 94 3.5E-31 T 29-03-2018 IPR012504 Sporulation protein YabP A616_RS00745 e1f2dc8c4171020127c73d3cac9b63ae 94 Pfam PF07873 YabP family 10 75 3.3E-21 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC A616_RS29555 bf19a06d90e6bacc3b38b5aa7f0e56a0 83 SUPERFAMILY SSF117130 1 55 7.19E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A616_RS29555 bf19a06d90e6bacc3b38b5aa7f0e56a0 83 Hamap MF_00167 Carbon storage regulator [csrA]. 1 79 20.657 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A616_RS29555 bf19a06d90e6bacc3b38b5aa7f0e56a0 83 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 59 1.5E-26 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A616_RS29555 bf19a06d90e6bacc3b38b5aa7f0e56a0 83 Pfam PF02599 Global regulator protein family 1 53 8.4E-26 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A616_RS29555 bf19a06d90e6bacc3b38b5aa7f0e56a0 83 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 4.0E-14 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A616_RS25555 65d500985c11fa28deda4282239d75ce 128 SUPERFAMILY SSF55729 9 125 1.05E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25555 65d500985c11fa28deda4282239d75ce 128 Gene3D G3DSA:3.40.630.30 9 100 7.4E-8 T 29-03-2018 A616_RS29775 f9a8e40ca6735112e630907e83cdfe4f 152 SUPERFAMILY SSF54637 6 143 4.93E-49 T 29-03-2018 IPR029069 HotDog domain A616_RS29775 f9a8e40ca6735112e630907e83cdfe4f 152 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 7 143 2.3E-57 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A616_RS29775 f9a8e40ca6735112e630907e83cdfe4f 152 Gene3D G3DSA:3.10.129.10 2 151 5.7E-55 T 29-03-2018 A616_RS29775 f9a8e40ca6735112e630907e83cdfe4f 152 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 7 146 33.882 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A616_RS29775 f9a8e40ca6735112e630907e83cdfe4f 152 Pfam PF07977 FabA-like domain 16 137 2.3E-34 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A616_RS20555 5e458d958ac591bc0797a065427f33fd 586 Gene3D G3DSA:3.90.1200.10 138 362 1.4E-12 T 29-03-2018 A616_RS20555 5e458d958ac591bc0797a065427f33fd 586 Gene3D G3DSA:3.30.200.20 26 126 1.8E-14 T 29-03-2018 A616_RS20555 5e458d958ac591bc0797a065427f33fd 586 SUPERFAMILY SSF56112 31 323 7.65E-34 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS20555 5e458d958ac591bc0797a065427f33fd 586 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 53 360 2.0E-82 T 29-03-2018 IPR014255 Spore coat protein CotS A616_RS00835 b2f57c839ed327fcace0559cad4d22f2 164 Pfam PF13798 Protein of unknown function with PCYCGC motif 12 163 1.5E-71 T 29-03-2018 IPR025673 Protein of unknown function with PCYCGC motif A616_RS16965 6320eae5d14d6251d1fa0651fc27619b 341 SUPERFAMILY SSF56349 44 221 2.06E-12 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS16965 6320eae5d14d6251d1fa0651fc27619b 341 Gene3D G3DSA:1.10.443.10 121 300 1.2E-8 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS27675 0db197b95f6668e4742e259ebc308387 184 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 9 181 1.9E-60 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS27675 0db197b95f6668e4742e259ebc308387 184 PIRSF PIRSF016897 1 184 6.7E-62 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS27675 0db197b95f6668e4742e259ebc308387 184 Gene3D G3DSA:3.20.20.400 1 182 1.1E-65 T 29-03-2018 A616_RS27675 0db197b95f6668e4742e259ebc308387 184 SUPERFAMILY SSF110391 9 182 3.92E-55 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 A616_RS19085 0197461946f9d2e0b377ae563d3a3b7d 191 Pfam PF14091 Domain of unknown function (DUF4269) 23 173 6.6E-56 T 29-03-2018 IPR025365 Protein of unknown function DUF4269 A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 Gene3D G3DSA:1.10.150.130 1 109 2.7E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 SUPERFAMILY SSF56349 3 287 5.0E-61 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 58.057 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 Pfam PF00589 Phage integrase family 109 280 1.6E-53 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 6 295 2.8E-121 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 Gene3D G3DSA:1.10.443.10 110 289 1.6E-51 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 295 60.994 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A616_RS13340 8ae13ebd8def847915aad0fd217980e0 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 2.1E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 TIGRFAM TIGR00109 hemH: ferrochelatase 2 308 3.0E-80 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 SUPERFAMILY SSF53800 3 308 1.03E-84 T 29-03-2018 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 30.213 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 Gene3D G3DSA:3.40.50.1400 158 289 1.0E-41 T 29-03-2018 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 Pfam PF00762 Ferrochelatase 5 307 4.4E-78 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 Gene3D G3DSA:3.40.50.1400 1 157 1.7E-19 T 29-03-2018 A616_RS10400 4a56ced3ae915d03c2ff328a60f50d4d 310 ProSitePatterns PS00534 Ferrochelatase signature. 178 196 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A616_RS08365 a4ae7a72c7a672753eda6fbafcd25491 1031 Gene3D G3DSA:2.60.120.260 233 469 0.032 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS08365 a4ae7a72c7a672753eda6fbafcd25491 1031 Gene3D G3DSA:3.40.630.30 2 170 7.0E-24 T 29-03-2018 A616_RS08365 a4ae7a72c7a672753eda6fbafcd25491 1031 SUPERFAMILY SSF55729 5 147 2.62E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS08365 a4ae7a72c7a672753eda6fbafcd25491 1031 Pfam PF00583 Acetyltransferase (GNAT) family 34 134 2.7E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS09670 e5ee82c99d2eca2534599cffeb7154ae 550 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 364 511 1.3E-24 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A616_RS09670 e5ee82c99d2eca2534599cffeb7154ae 550 Pfam PF01943 Polysaccharide biosynthesis protein 8 312 1.5E-33 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A616_RS09670 e5ee82c99d2eca2534599cffeb7154ae 550 PIRSF PIRSF038958 2 530 1.1E-89 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type A616_RS12240 0ec927f408382447a55ea121a82fca7d 161 Pfam PF01047 MarR family 50 108 1.1E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS12240 0ec927f408382447a55ea121a82fca7d 161 SMART SM00347 43 146 8.8E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS12240 0ec927f408382447a55ea121a82fca7d 161 SUPERFAMILY SSF46785 31 158 4.82E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12240 0ec927f408382447a55ea121a82fca7d 161 Gene3D G3DSA:1.10.10.10 17 148 5.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18175 9c0df8c32e8769a271988ff586f330e4 164 Gene3D G3DSA:3.10.129.10 1 163 2.6E-47 T 29-03-2018 A616_RS18175 9c0df8c32e8769a271988ff586f330e4 164 Pfam PF03061 Thioesterase superfamily 34 105 1.9E-15 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS18175 9c0df8c32e8769a271988ff586f330e4 164 SUPERFAMILY SSF54637 12 161 8.11E-46 T 29-03-2018 IPR029069 HotDog domain A616_RS27320 247fdb3f86b21b0bbd0d80308c03fc67 126 Gene3D G3DSA:3.10.180.10 2 126 3.4E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS27320 247fdb3f86b21b0bbd0d80308c03fc67 126 SUPERFAMILY SSF54593 1 125 3.03E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS27320 247fdb3f86b21b0bbd0d80308c03fc67 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 116 1.1E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS31285 caf6a9f85b299556e67ccd3fda4936b2 210 Gene3D G3DSA:2.30.30.410 59 141 0.005 T 29-03-2018 A616_RS31285 caf6a9f85b299556e67ccd3fda4936b2 210 Gene3D G3DSA:2.40.50.110 142 209 0.0071 T 29-03-2018 A616_RS02360 f9a7aa3ba1c43f54a2d052ffa5e1dbed 171 Gene3D G3DSA:3.40.630.30 2 163 2.1E-28 T 29-03-2018 A616_RS02360 f9a7aa3ba1c43f54a2d052ffa5e1dbed 171 SUPERFAMILY SSF55729 8 157 4.29E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS02360 f9a7aa3ba1c43f54a2d052ffa5e1dbed 171 Pfam PF13302 Acetyltransferase (GNAT) domain 13 150 1.4E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS10430 9dcf7991f6149bf9bace53dca3e824c9 400 SMART SM00331 172 391 2.5E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS10430 9dcf7991f6149bf9bace53dca3e824c9 400 Gene3D G3DSA:3.60.40.10 138 393 3.8E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS10430 9dcf7991f6149bf9bace53dca3e824c9 400 SUPERFAMILY SSF81606 184 392 1.44E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS10430 9dcf7991f6149bf9bace53dca3e824c9 400 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 199 391 4.8E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS05550 fde28776e4d4e07df246ce0a9b0cd0e2 235 Pfam PF08713 DNA alkylation repair enzyme 6 193 2.3E-19 T 29-03-2018 IPR014825 DNA alkylation repair enzyme A616_RS05550 fde28776e4d4e07df246ce0a9b0cd0e2 235 SUPERFAMILY SSF48371 1 235 1.76E-66 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 Gene3D G3DSA:3.50.50.60 2 170 5.0E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 Pfam PF12831 FAD dependent oxidoreductase 6 147 2.5E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.9E-12 T 29-03-2018 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 1.9E-12 T 29-03-2018 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.9E-12 T 29-03-2018 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 347 1.9E-12 T 29-03-2018 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 SUPERFAMILY SSF54373 182 284 5.89E-18 T 29-03-2018 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 SUPERFAMILY SSF51905 1 184 5.75E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 SUPERFAMILY SSF51905 284 380 5.75E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS10005 c91f97b325c710108ca142a71497dda2 431 Gene3D G3DSA:3.30.9.10 171 336 1.4E-21 T 29-03-2018 A616_RS28515 a2d54a14ccc50186a1a7948d781ce4fe 108 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 34 103 5.0E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS28515 a2d54a14ccc50186a1a7948d781ce4fe 108 SUPERFAMILY SSF46626 1 105 1.58E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS28515 a2d54a14ccc50186a1a7948d781ce4fe 108 PIRSF PIRSF000025 1 107 7.2E-25 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 A616_RS28515 a2d54a14ccc50186a1a7948d781ce4fe 108 Gene3D G3DSA:1.10.760.10 19 108 4.3E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A616_RS12025 207e2d4395168d9da19789cf306f63ec 357 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 20 357 2.1E-153 T 29-03-2018 IPR023897 Spore photoproduct lyase GO:0003913 A616_RS12025 207e2d4395168d9da19789cf306f63ec 357 Gene3D G3DSA:3.80.30.20 94 320 7.9E-9 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 Gene3D G3DSA:1.10.10.10 1 91 8.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 SUPERFAMILY SSF53850 98 291 3.57E-38 T 29-03-2018 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 Gene3D G3DSA:3.40.190.10 92 173 7.6E-16 T 29-03-2018 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 Gene3D G3DSA:3.40.190.10 174 262 1.2E-24 T 29-03-2018 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 Pfam PF03466 LysR substrate binding domain 96 287 1.1E-41 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS23520 7135f18afb0f0ee61497d8f185d85bec 293 SUPERFAMILY SSF46785 1 85 5.44E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25315 b9008b9a9f2c986de0604cefcf1ee03b 226 SUPERFAMILY SSF110395 1 223 6.93E-62 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A616_RS25315 b9008b9a9f2c986de0604cefcf1ee03b 226 Pfam PF03932 CutC family 1 201 8.7E-59 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A616_RS25315 b9008b9a9f2c986de0604cefcf1ee03b 226 Gene3D G3DSA:3.20.20.380 1 223 9.6E-72 T 29-03-2018 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 SUPERFAMILY SSF53067 84 129 9.06E-15 T 29-03-2018 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 SUPERFAMILY SSF53067 171 360 9.06E-15 T 29-03-2018 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 SUPERFAMILY SSF53067 19 52 9.06E-15 T 29-03-2018 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 18 404 1.8E-105 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 16 406 36.285 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 Gene3D G3DSA:3.30.420.40 16 218 7.0E-52 T 29-03-2018 A616_RS08795 d5d7c832cc98f4fa442842821c7cd6c1 406 Gene3D G3DSA:3.30.420.40 274 406 2.7E-23 T 29-03-2018 A616_RS05700 c384c954b940c9d30f1c1f882637a901 192 SUPERFAMILY SSF53335 23 156 3.53E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS05700 c384c954b940c9d30f1c1f882637a901 192 Gene3D G3DSA:3.40.50.150 25 183 1.1E-19 T 29-03-2018 A616_RS05700 c384c954b940c9d30f1c1f882637a901 192 Pfam PF13649 Methyltransferase domain 44 141 8.8E-8 T 29-03-2018 A616_RS01060 01a9a596df9462f594b79756eae0d94d 312 Gene3D G3DSA:1.10.3720.10 3 293 7.8E-41 T 29-03-2018 A616_RS01060 01a9a596df9462f594b79756eae0d94d 312 SUPERFAMILY SSF161098 89 287 1.39E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS01060 01a9a596df9462f594b79756eae0d94d 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.3E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS27395 d114ff30a71864ce39dc4262e5c006db 304 Pfam PF02628 Cytochrome oxidase assembly protein 54 285 3.2E-31 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 A616_RS12155 1423efce540e6bab0f60099188b8216b 217 Gene3D G3DSA:1.10.4030.10 29 136 1.1E-11 T 29-03-2018 A616_RS12155 1423efce540e6bab0f60099188b8216b 217 Pfam PF13624 SurA N-terminal domain 11 131 5.5E-10 T 29-03-2018 A616_RS12155 1423efce540e6bab0f60099188b8216b 217 SUPERFAMILY SSF109998 37 166 3.14E-19 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS21215 2d949333f7919af26840a720d57d7498 87 Pfam PF02325 YGGT family 10 77 1.4E-21 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 A616_RS31880 273e80d4bf9643951b54b37ff6b39080 351 SUPERFAMILY SSF51679 13 347 3.79E-66 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS31880 273e80d4bf9643951b54b37ff6b39080 351 Gene3D G3DSA:3.20.20.30 1 351 2.5E-65 T 29-03-2018 A616_RS31880 273e80d4bf9643951b54b37ff6b39080 351 Pfam PF00296 Luciferase-like monooxygenase 24 309 1.8E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS16230 0e5ea105603eb3ffbf71e734f01e6016 261 Gene3D G3DSA:3.90.850.10 1 261 5.3E-47 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS16230 0e5ea105603eb3ffbf71e734f01e6016 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 101 255 5.3E-10 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS16230 0e5ea105603eb3ffbf71e734f01e6016 261 SUPERFAMILY SSF56529 2 259 2.22E-74 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS09130 54d65042c4c4c079e3893e3b137d83c7 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 303 5.8E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09130 54d65042c4c4c079e3893e3b137d83c7 316 Gene3D G3DSA:1.10.3720.10 80 310 6.8E-48 T 29-03-2018 A616_RS09130 54d65042c4c4c079e3893e3b137d83c7 316 SUPERFAMILY SSF161098 74 303 4.45E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09130 54d65042c4c4c079e3893e3b137d83c7 316 Gene3D G3DSA:1.20.58.370 9 62 3.7E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS13330 5fb30055a3d19b8e7968fe0959a1d1b7 154 Pfam PF01475 Ferric uptake regulator family 16 138 8.2E-37 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A616_RS13330 5fb30055a3d19b8e7968fe0959a1d1b7 154 SUPERFAMILY SSF46785 7 142 6.35E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13330 5fb30055a3d19b8e7968fe0959a1d1b7 154 Gene3D G3DSA:1.10.10.10 9 98 5.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19415 c0c2e4c82f7b356b9635ccb264408a90 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 41 73 1.1E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS02765 a9ba088361ea6acd2c5b335ae67f1ca5 309 Gene3D G3DSA:3.40.190.10 183 307 4.6E-21 T 29-03-2018 A616_RS02765 a9ba088361ea6acd2c5b335ae67f1ca5 309 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 292 9.5E-82 T 29-03-2018 IPR011862 Phosphate binding protein GO:0006810 A616_RS02765 a9ba088361ea6acd2c5b335ae67f1ca5 309 SUPERFAMILY SSF53850 54 301 5.65E-75 T 29-03-2018 A616_RS02765 a9ba088361ea6acd2c5b335ae67f1ca5 309 Gene3D G3DSA:3.40.190.10 49 182 3.7E-29 T 29-03-2018 A616_RS02765 a9ba088361ea6acd2c5b335ae67f1ca5 309 Pfam PF12849 PBP superfamily domain 45 279 9.6E-40 T 29-03-2018 IPR024370 PBP domain A616_RS09045 74b9ade4ea7853921cc8af7f3dda0558 324 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 124 3.1E-27 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A616_RS09045 74b9ade4ea7853921cc8af7f3dda0558 324 Gene3D G3DSA:3.30.360.10 147 315 5.2E-18 T 29-03-2018 A616_RS09045 74b9ade4ea7853921cc8af7f3dda0558 324 SUPERFAMILY SSF51735 6 152 6.54E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS09045 74b9ade4ea7853921cc8af7f3dda0558 324 SUPERFAMILY SSF55347 142 265 4.14E-12 T 29-03-2018 A616_RS09045 74b9ade4ea7853921cc8af7f3dda0558 324 Gene3D G3DSA:3.40.50.720 2 146 5.2E-38 T 29-03-2018 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Gene3D G3DSA:2.40.50.110 22 89 3.4E-15 T 29-03-2018 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Gene3D G3DSA:2.40.50.110 90 156 7.5E-11 T 29-03-2018 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Gene3D G3DSA:2.40.50.110 187 252 1.9E-6 T 29-03-2018 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Gene3D G3DSA:2.40.50.110 270 344 1.9E-10 T 29-03-2018 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Gene3D G3DSA:3.40.630.40 365 577 5.8E-13 T 29-03-2018 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 369 571 2.3E-54 T 29-03-2018 IPR010897 Sporulation stage II, protein P A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 SMART SM00287 282 344 2.6E-6 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 SMART SM00287 92 157 1.4E-4 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 SMART SM00287 195 256 0.41 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 SMART SM00287 27 89 4.3E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Pfam PF06347 Bacterial SH3 domain 102 154 5.8E-5 T 29-03-2018 IPR010466 Protein of unknown function DUF1058 A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Pfam PF08239 Bacterial SH3 domain 293 339 1.6E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Pfam PF08239 Bacterial SH3 domain 36 87 4.6E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS25440 82d6b53cc8e3a9c09dd818e94ef719ce 579 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 362 567 5.1E-61 T 29-03-2018 IPR010897 Sporulation stage II, protein P A616_RS27480 55f752dad05c53f180dd66ec2597258a 141 SUPERFAMILY SSF54637 5 133 2.21E-29 T 29-03-2018 IPR029069 HotDog domain A616_RS27480 55f752dad05c53f180dd66ec2597258a 141 Gene3D G3DSA:3.10.129.10 1 139 3.4E-18 T 29-03-2018 A616_RS28900 acc42685ab4d81d60e755da50dca7b87 327 Gene3D G3DSA:3.90.70.10 12 177 2.4E-4 T 29-03-2018 A616_RS17805 b3d002396c24e3f8bd56beabedcf566e 393 Gene3D G3DSA:1.20.1250.20 2 189 2.7E-38 T 29-03-2018 A616_RS17805 b3d002396c24e3f8bd56beabedcf566e 393 Gene3D G3DSA:1.20.1250.20 197 389 5.4E-22 T 29-03-2018 A616_RS17805 b3d002396c24e3f8bd56beabedcf566e 393 SUPERFAMILY SSF103473 5 377 1.96E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS17805 b3d002396c24e3f8bd56beabedcf566e 393 Pfam PF07690 Major Facilitator Superfamily 8 343 1.3E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS08110 7de2212909cad22d0922f8403a5eb393 310 Gene3D G3DSA:3.40.50.300 109 303 7.1E-21 T 29-03-2018 A616_RS08110 7de2212909cad22d0922f8403a5eb393 310 SMART SM00382 160 289 4.7E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08110 7de2212909cad22d0922f8403a5eb393 310 Pfam PF01695 IstB-like ATP binding protein 161 275 1.2E-13 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A616_RS08110 7de2212909cad22d0922f8403a5eb393 310 Pfam PF07319 Primosomal protein DnaI N-terminus 2 95 1.0E-15 T 29-03-2018 IPR009928 Primosomal DnaI, N-terminal A616_RS08110 7de2212909cad22d0922f8403a5eb393 310 SUPERFAMILY SSF52540 128 274 1.61E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21570 4847b8079eaa8bfd0cfe55763de8156e 211 Pfam PF06335 Protein of unknown function (DUF1054) 7 204 4.7E-82 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 A616_RS21570 4847b8079eaa8bfd0cfe55763de8156e 211 Hamap MF_01851 UPF0637 protein . 6 206 36.609 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 A616_RS21570 4847b8079eaa8bfd0cfe55763de8156e 211 PIRSF PIRSF021332 2 209 1.1E-79 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 A616_RS21570 4847b8079eaa8bfd0cfe55763de8156e 211 SUPERFAMILY SSF142913 3 206 1.44E-76 T 29-03-2018 A616_RS31155 bc47ec9360c2d155ed1b91d0de29940a 220 Gene3D G3DSA:1.10.3720.10 5 219 4.4E-38 T 29-03-2018 A616_RS31155 bc47ec9360c2d155ed1b91d0de29940a 220 SUPERFAMILY SSF161098 10 203 8.63E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS31155 bc47ec9360c2d155ed1b91d0de29940a 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 9.9E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS23615 ddbb67f13750f45722a1d948bbd845da 434 Pfam PF01435 Peptidase family M48 163 391 1.0E-16 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A616_RS23615 ddbb67f13750f45722a1d948bbd845da 434 Gene3D G3DSA:3.30.2010.10 148 240 1.8E-9 T 29-03-2018 A616_RS11585 5918319028f5c13daff131243d259038 107 Pfam PF01230 HIT domain 12 104 6.9E-23 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS11585 5918319028f5c13daff131243d259038 107 SUPERFAMILY SSF54197 1 105 7.27E-33 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS11585 5918319028f5c13daff131243d259038 107 Gene3D G3DSA:3.30.428.10 1 105 3.0E-29 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS11585 5918319028f5c13daff131243d259038 107 PRINTS PR00332 Histidine triad family signature 92 102 1.8E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS11585 5918319028f5c13daff131243d259038 107 PRINTS PR00332 Histidine triad family signature 26 44 1.8E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS11585 5918319028f5c13daff131243d259038 107 PRINTS PR00332 Histidine triad family signature 5 21 1.8E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS13400 ba14c97e97ebdd13b1bfa889d99c2cc1 116 SUPERFAMILY SSF52091 4 111 1.33E-29 T 29-03-2018 IPR002645 STAS domain A616_RS13400 ba14c97e97ebdd13b1bfa889d99c2cc1 116 Gene3D G3DSA:3.30.750.24 1 114 3.7E-25 T 29-03-2018 IPR002645 STAS domain A616_RS13400 ba14c97e97ebdd13b1bfa889d99c2cc1 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 6 110 2.1E-44 T 29-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 A616_RS13400 ba14c97e97ebdd13b1bfa889d99c2cc1 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 1.0E-35 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 A616_RS13400 ba14c97e97ebdd13b1bfa889d99c2cc1 116 Pfam PF01740 STAS domain 6 109 5.8E-25 T 29-03-2018 IPR002645 STAS domain A616_RS04255 6747bf6dd9304f697ccd26a35cea5604 114 Gene3D G3DSA:3.30.420.10 62 113 5.5E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS04255 6747bf6dd9304f697ccd26a35cea5604 114 Pfam PF13276 HTH-like domain 1 46 1.3E-12 T 29-03-2018 IPR025948 HTH-like domain A616_RS04255 6747bf6dd9304f697ccd26a35cea5604 114 Gene3D G3DSA:1.10.10.10 1 54 5.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08555 dbdd6a853da40ec659fc087db6c68349 247 SMART SM00382 29 214 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08555 dbdd6a853da40ec659fc087db6c68349 247 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08555 dbdd6a853da40ec659fc087db6c68349 247 Gene3D G3DSA:3.40.50.300 2 241 4.3E-61 T 29-03-2018 A616_RS08555 dbdd6a853da40ec659fc087db6c68349 247 SUPERFAMILY SSF52540 4 227 7.79E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08555 dbdd6a853da40ec659fc087db6c68349 247 Pfam PF00005 ABC transporter 21 165 1.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS06340 8f21d751da5639cd0ec62a5bb509359e 440 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 34 415 3.3E-65 T 29-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 A616_RS06340 8f21d751da5639cd0ec62a5bb509359e 440 Pfam PF03237 Terminase-like family 40 235 3.1E-9 T 29-03-2018 A616_RS26170 eab0ab09e0cfb5649621cba6063030c1 197 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 133 192 3.2E-17 T 29-03-2018 A616_RS26170 eab0ab09e0cfb5649621cba6063030c1 197 Pfam PF08818 Domain of unknown function (DU1801) 20 117 1.1E-13 T 29-03-2018 IPR014922 Domain of unknown function DUF1801 A616_RS26170 eab0ab09e0cfb5649621cba6063030c1 197 PIRSF PIRSF021308 1 197 1.5E-96 T 29-03-2018 IPR016786 Uncharacterised protein YdeI, bacterial A616_RS26170 eab0ab09e0cfb5649621cba6063030c1 197 SUPERFAMILY SSF159888 9 125 6.8E-21 T 29-03-2018 A616_RS10500 798399200206e52c056b6be6d063579e 319 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 7 284 1.5E-44 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A616_RS10500 798399200206e52c056b6be6d063579e 319 Pfam PF04085 rod shape-determining protein MreC 122 281 1.2E-40 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A616_RS10500 798399200206e52c056b6be6d063579e 319 PIRSF PIRSF038471 1 292 1.2E-60 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A616_RS24045 821fce3ffa415f999f251f3a819b68af 243 SUPERFAMILY SSF81301 3 200 1.31E-54 T 29-03-2018 A616_RS24045 821fce3ffa415f999f251f3a819b68af 243 Gene3D G3DSA:3.30.460.10 1 148 3.8E-33 T 29-03-2018 A616_RS24045 821fce3ffa415f999f251f3a819b68af 243 Pfam PF04607 Region found in RelA / SpoT proteins 45 164 1.6E-33 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 A616_RS24045 821fce3ffa415f999f251f3a819b68af 243 Gene3D G3DSA:1.10.287.860 150 198 6.5E-19 T 29-03-2018 A616_RS24045 821fce3ffa415f999f251f3a819b68af 243 SMART SM00954 45 167 2.4E-40 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 A616_RS06560 8863f42684f4c267fc7db3a834228ec6 184 Gene3D G3DSA:3.40.630.30 14 181 2.2E-14 T 29-03-2018 A616_RS06560 8863f42684f4c267fc7db3a834228ec6 184 SUPERFAMILY SSF55729 7 156 5.78E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS26010 255b0547c780741d04157bbe708737fd 67 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 6.0E-13 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 A616_RS27885 5126dfa18637c6501d38712881177cb7 102 Gene3D G3DSA:2.60.120.40 1 102 7.1E-11 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 A616_RS31335 6c683f7fae66fc6e18a8d34be76da679 365 Pfam PF02898 Nitric oxide synthase, oxygenase domain 5 360 1.4E-173 T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A616_RS31335 6c683f7fae66fc6e18a8d34be76da679 365 SUPERFAMILY SSF56512 5 361 5.76E-170 T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 A616_RS31335 6c683f7fae66fc6e18a8d34be76da679 365 Gene3D G3DSA:3.90.1230.10 193 303 5.5E-54 T 29-03-2018 A616_RS31335 6c683f7fae66fc6e18a8d34be76da679 365 PIRSF PIRSF037219 1 365 3.1E-185 T 29-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 A616_RS31335 6c683f7fae66fc6e18a8d34be76da679 365 Gene3D G3DSA:3.90.340.10 2 126 1.0E-46 T 29-03-2018 A616_RS09185 84eb701e65209425d4c20ac2ece474da 299 Gene3D G3DSA:1.10.3720.10 23 287 1.1E-50 T 29-03-2018 A616_RS09185 84eb701e65209425d4c20ac2ece474da 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 74 2.8E-16 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS09185 84eb701e65209425d4c20ac2ece474da 299 SUPERFAMILY SSF161098 92 284 7.59E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09185 84eb701e65209425d4c20ac2ece474da 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 298 1.3E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS13585 f96928a66ec5c13d504529d5f317201d 199 PIRSF PIRSF029008 1 199 7.6E-48 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA A616_RS13585 f96928a66ec5c13d504529d5f317201d 199 Pfam PF05389 Negative regulator of genetic competence (MecA) 84 194 7.3E-17 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA A616_RS13585 f96928a66ec5c13d504529d5f317201d 199 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 90 2.9E-22 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA A616_RS04830 08253be903c7e62ba39696effc23e89c 208 SUPERFAMILY SSF53335 12 155 2.67E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS04830 08253be903c7e62ba39696effc23e89c 208 Gene3D G3DSA:3.40.50.150 6 208 2.4E-11 T 29-03-2018 A616_RS04830 08253be903c7e62ba39696effc23e89c 208 Pfam PF13489 Methyltransferase domain 42 149 5.9E-10 T 29-03-2018 A616_RS30885 d7b17d1b37ab425258819f8ec17cf215 134 Gene3D G3DSA:3.40.630.40 1 128 1.0E-22 T 29-03-2018 A616_RS30885 d7b17d1b37ab425258819f8ec17cf215 134 SUPERFAMILY SSF53187 3 86 1.51E-19 T 29-03-2018 A616_RS30885 d7b17d1b37ab425258819f8ec17cf215 134 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 87 1.5E-19 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 11 205 6.0E-73 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 Gene3D G3DSA:3.30.559.10 1 211 1.3E-37 T 29-03-2018 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 Pfam PF00302 Chloramphenicol acetyltransferase 3 206 1.7E-83 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 PIRSF PIRSF000440 1 215 1.5E-82 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 SUPERFAMILY SSF52777 1 211 4.08E-73 T 29-03-2018 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 ProSitePatterns PS00100 Chloramphenicol acetyltransferase active site. 187 197 - T 29-03-2018 IPR018372 Chloramphenicol acetyltransferase, active site GO:0008811 A616_RS08490 baabec1e9cccafddd4178dcdb1db2867 219 SMART SM01059 1 206 1.3E-111 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 A616_RS30380 34f16ff851d767fdf7aafeee60deb104 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 7.7E-12 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A616_RS30380 34f16ff851d767fdf7aafeee60deb104 107 SUPERFAMILY SSF54909 1 92 9.84E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS30380 34f16ff851d767fdf7aafeee60deb104 107 Gene3D G3DSA:3.30.70.100 1 107 8.3E-20 T 29-03-2018 A616_RS15205 ddae244cbf772034e638606445d260ef 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 207 3.9E-17 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS15205 ddae244cbf772034e638606445d260ef 295 SUPERFAMILY SSF51735 1 279 3.11E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS15205 ddae244cbf772034e638606445d260ef 295 Gene3D G3DSA:3.40.50.720 1 291 8.3E-39 T 29-03-2018 A616_RS05320 f5e0ac5e068b5f849d3679628dd7e3df 151 SUPERFAMILY SSF109854 4 146 1.83E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS05320 f5e0ac5e068b5f849d3679628dd7e3df 151 Gene3D G3DSA:1.20.120.450 1 146 5.5E-25 T 29-03-2018 A616_RS05320 f5e0ac5e068b5f849d3679628dd7e3df 151 Pfam PF12867 DinB superfamily 10 141 2.7E-18 T 29-03-2018 IPR024775 DinB-like domain A616_RS18925 966488a6c79ebf2b03625f308b169f75 103 Gene3D G3DSA:1.10.287.880 2 49 4.4E-15 T 29-03-2018 A616_RS18925 966488a6c79ebf2b03625f308b169f75 103 SUPERFAMILY SSF101697 4 98 3.14E-23 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 A616_RS18925 966488a6c79ebf2b03625f308b169f75 103 Gene3D G3DSA:2.30.30.340 50 100 7.0E-15 T 29-03-2018 A616_RS18925 966488a6c79ebf2b03625f308b169f75 103 Pfam PF08838 Protein of unknown function (DUF1811) 3 99 2.7E-32 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 A616_RS23680 13dcf723e88c0aab69496ae61e4f310c 474 Gene3D G3DSA:2.40.440.10 329 441 4.3E-27 T 29-03-2018 A616_RS23680 13dcf723e88c0aab69496ae61e4f310c 474 Gene3D G3DSA:1.25.40.10 22 96 5.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS23680 13dcf723e88c0aab69496ae61e4f310c 474 Pfam PF03734 L,D-transpeptidase catalytic domain 338 436 4.6E-16 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A616_RS23680 13dcf723e88c0aab69496ae61e4f310c 474 SUPERFAMILY SSF141523 328 439 9.42E-27 T 29-03-2018 A616_RS23680 13dcf723e88c0aab69496ae61e4f310c 474 SUPERFAMILY SSF48452 24 89 1.79E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS18170 7998fb34fb2e01a3363808413450ac17 150 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 7 130 7.7E-27 T 29-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 A616_RS18170 7998fb34fb2e01a3363808413450ac17 150 Gene3D G3DSA:3.10.450.50 3 137 5.9E-12 T 29-03-2018 A616_RS18170 7998fb34fb2e01a3363808413450ac17 150 SUPERFAMILY SSF54427 8 145 3.56E-25 T 29-03-2018 IPR032710 NTF2-like domain A616_RS23570 35298a9c609780f1fc20990d7a6d5770 200 Pfam PF12840 Helix-turn-helix domain 14 69 1.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23570 35298a9c609780f1fc20990d7a6d5770 200 SMART SM00418 13 92 5.0E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS23570 35298a9c609780f1fc20990d7a6d5770 200 SUPERFAMILY SSF46785 6 114 2.92E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23570 35298a9c609780f1fc20990d7a6d5770 200 Gene3D G3DSA:1.10.10.10 11 178 9.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS03425 285c9e46089741fd45d41da712eb1791 308 Pfam PF00482 Type II secretion system (T2SS), protein F 142 266 4.7E-22 T 29-03-2018 IPR018076 Type II secretion system F domain A616_RS18665 0c0b7244244b377505b3daa7be74b22c 138 Pfam PF11255 Protein of unknown function (DUF3054) 13 120 8.8E-23 T 29-03-2018 IPR021414 Protein of unknown function DUF3054 A616_RS10390 b28b4ec59738035b6f8fffe0df9e6d59 282 Gene3D G3DSA:2.60.40.60 28 282 0.0032 T 29-03-2018 A616_RS10390 b28b4ec59738035b6f8fffe0df9e6d59 282 Pfam PF13349 Putative adhesin 50 281 2.3E-21 T 29-03-2018 IPR025164 Putative adhesin A616_RS08305 f94467a7b55a0f4997a8acc6f7c69ce0 188 Pfam PF13271 Domain of unknown function (DUF4062) 6 86 2.8E-21 T 29-03-2018 IPR025139 Domain of unknown function DUF4062 A616_RS08305 f94467a7b55a0f4997a8acc6f7c69ce0 188 Gene3D G3DSA:3.40.50.450 1 157 8.9E-5 T 29-03-2018 A616_RS02180 381c5db2e106eda1e96b551a45b05735 208 Pfam PF02525 Flavodoxin-like fold 3 203 1.6E-36 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS02180 381c5db2e106eda1e96b551a45b05735 208 SUPERFAMILY SSF52218 1 206 1.73E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS02180 381c5db2e106eda1e96b551a45b05735 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 27.007 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A616_RS02180 381c5db2e106eda1e96b551a45b05735 208 Gene3D G3DSA:3.40.50.360 3 208 1.8E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS32105 f126d6216b74bb6ae0c6965dc41b0fc5 262 Pfam PF00753 Metallo-beta-lactamase superfamily 10 216 1.5E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS32105 f126d6216b74bb6ae0c6965dc41b0fc5 262 Gene3D G3DSA:3.60.15.10 7 253 1.4E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS32105 f126d6216b74bb6ae0c6965dc41b0fc5 262 SMART SM00849 11 216 1.5E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS32105 f126d6216b74bb6ae0c6965dc41b0fc5 262 SUPERFAMILY SSF56281 6 230 2.62E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS24125 02e4e65087b3ae532530d48e6790cb8a 368 SUPERFAMILY SSF56059 188 346 2.53E-11 T 29-03-2018 A616_RS24125 02e4e65087b3ae532530d48e6790cb8a 368 SUPERFAMILY SSF56059 121 164 2.53E-11 T 29-03-2018 A616_RS24125 02e4e65087b3ae532530d48e6790cb8a 368 Gene3D G3DSA:3.30.470.20 202 339 6.0E-11 T 29-03-2018 A616_RS24125 02e4e65087b3ae532530d48e6790cb8a 368 Pfam PF14398 YheC/D like ATP-grasp 97 355 1.5E-80 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS24125 02e4e65087b3ae532530d48e6790cb8a 368 Gene3D G3DSA:3.30.1490.20 128 201 1.7E-10 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS15075 00ed6962cc4497f32959297a4884003b 280 Gene3D G3DSA:3.40.190.10 139 280 4.0E-52 T 29-03-2018 A616_RS15075 00ed6962cc4497f32959297a4884003b 280 Gene3D G3DSA:3.40.190.10 41 138 2.2E-19 T 29-03-2018 A616_RS15075 00ed6962cc4497f32959297a4884003b 280 PIRSF PIRSF002854 1 280 2.8E-101 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS15075 00ed6962cc4497f32959297a4884003b 280 SUPERFAMILY SSF53850 44 280 2.72E-76 T 29-03-2018 A616_RS15075 00ed6962cc4497f32959297a4884003b 280 Pfam PF03180 NLPA lipoprotein 45 280 2.5E-84 T 29-03-2018 IPR004872 Lipoprotein NlpA family A616_RS10155 9a04669eb09c4060865e2c57ed907038 587 Pfam PF02494 HYR domain 323 351 3.1E-6 T 29-03-2018 IPR003410 HYR domain A616_RS10155 9a04669eb09c4060865e2c57ed907038 587 Gene3D G3DSA:2.60.40.10 261 354 1.3E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS26765 5268b2e8e2452de007a05460bc5b824d 145 Gene3D G3DSA:3.90.1010.10 1 140 1.2E-50 T 29-03-2018 A616_RS26765 5268b2e8e2452de007a05460bc5b824d 145 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 4 139 1.0E-56 T 29-03-2018 A616_RS26765 5268b2e8e2452de007a05460bc5b824d 145 SUPERFAMILY SSF82649 1 143 5.76E-51 T 29-03-2018 A616_RS26765 5268b2e8e2452de007a05460bc5b824d 145 Pfam PF01592 NifU-like N terminal domain 8 127 3.9E-32 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A616_RS23495 e1be9afca9e96456f2f6680ea8520cca 78 Pfam PF13046 Protein of unknown function (DUF3906) 8 72 8.5E-16 T 29-03-2018 IPR024998 Protein of unknown function DUF3906 A616_RS22540 230493546609102c138b55d4b95eb90f 171 Gene3D G3DSA:3.40.190.10 1 168 3.3E-5 T 29-03-2018 A616_RS25015 d937d3c682b8d68d625ebd3e5fbe3fa3 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 211 6.9E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25015 d937d3c682b8d68d625ebd3e5fbe3fa3 229 Gene3D G3DSA:1.10.3720.10 4 217 2.4E-48 T 29-03-2018 A616_RS25015 d937d3c682b8d68d625ebd3e5fbe3fa3 229 SUPERFAMILY SSF161098 11 197 1.07E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25015 d937d3c682b8d68d625ebd3e5fbe3fa3 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 8.4E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS08550 b9bf3df9e9ca6fa7a0249bbd3cb5b518 456 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A616_RS08550 b9bf3df9e9ca6fa7a0249bbd3cb5b518 456 PIRSF PIRSF006060 1 455 4.3E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS08550 b9bf3df9e9ca6fa7a0249bbd3cb5b518 456 Pfam PF00324 Amino acid permease 14 445 1.9E-115 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A616_RS11635 c9df0094833326ece43f729b6a849eab 159 Gene3D G3DSA:3.40.390.30 1 159 2.0E-51 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 A616_RS11635 c9df0094833326ece43f729b6a849eab 159 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 156 1.1E-41 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A616_RS11635 c9df0094833326ece43f729b6a849eab 159 Pfam PF02130 Uncharacterized protein family UPF0054 14 154 8.0E-49 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A616_RS11635 c9df0094833326ece43f729b6a849eab 159 SUPERFAMILY SSF55486 18 158 6.1E-43 T 29-03-2018 A616_RS11635 c9df0094833326ece43f729b6a849eab 159 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 159 24.185 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A616_RS11635 c9df0094833326ece43f729b6a849eab 159 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 125 135 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site A616_RS08025 4af3933b078bafd9b940183272a02190 362 SUPERFAMILY SSF52540 216 317 7.82E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08025 4af3933b078bafd9b940183272a02190 362 Gene3D G3DSA:3.40.50.300 211 354 6.1E-7 T 29-03-2018 A616_RS00765 581ada621e58fff0f6d0d7e7deb4d3bf 824 SMART SM00331 587 799 7.6E-45 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS00765 581ada621e58fff0f6d0d7e7deb4d3bf 824 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 45 799 1.5E-240 T 29-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS00765 581ada621e58fff0f6d0d7e7deb4d3bf 824 SMART SM00332 581 797 8.9E-4 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS00765 581ada621e58fff0f6d0d7e7deb4d3bf 824 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 614 799 4.7E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS00765 581ada621e58fff0f6d0d7e7deb4d3bf 824 SUPERFAMILY SSF81606 590 800 5.89E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS00765 581ada621e58fff0f6d0d7e7deb4d3bf 824 Gene3D G3DSA:3.60.40.10 577 805 2.9E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A616_RS19375 9e4509aabf3cd10a133f94b39ba7f055 85 Pfam PF09643 YopX protein 15 74 3.1E-13 T 29-03-2018 IPR019096 YopX protein A616_RS19375 9e4509aabf3cd10a133f94b39ba7f055 85 Gene3D G3DSA:2.30.30.290 31 83 2.4E-12 T 29-03-2018 IPR023385 YopX-like domain, beta barrel type A616_RS19375 9e4509aabf3cd10a133f94b39ba7f055 85 SUPERFAMILY SSF159006 21 76 1.09E-14 T 29-03-2018 A616_RS10860 fa8bf79e5a980e8fe1160c391a59b100 216 Pfam PF01596 O-methyltransferase 13 209 7.0E-32 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 A616_RS10860 fa8bf79e5a980e8fe1160c391a59b100 216 SUPERFAMILY SSF53335 2 207 1.27E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10860 fa8bf79e5a980e8fe1160c391a59b100 216 Gene3D G3DSA:3.40.50.150 1 215 2.7E-40 T 29-03-2018 A616_RS07510 525b4e30e07c7004f59756aebdf3019f 297 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 55 227 6.1E-6 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system A616_RS22205 2689f6f7cfc471f9c8f05d28bbac76ab 120 SUPERFAMILY SSF160755 1 113 9.81E-22 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS22205 2689f6f7cfc471f9c8f05d28bbac76ab 120 Gene3D G3DSA:3.30.310.100 1 115 4.3E-22 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like A616_RS25530 876b6d1ec3a698c07e80d1f3e5f285e1 312 Gene3D G3DSA:1.10.3720.10 77 309 1.7E-47 T 29-03-2018 A616_RS25530 876b6d1ec3a698c07e80d1f3e5f285e1 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 304 1.1E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25530 876b6d1ec3a698c07e80d1f3e5f285e1 312 Gene3D G3DSA:1.20.58.370 19 62 4.3E-8 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain A616_RS25530 876b6d1ec3a698c07e80d1f3e5f285e1 312 SUPERFAMILY SSF161098 72 299 1.31E-66 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS05540 4919d5ee047d666a6839a22791b4ed7b 774 Pfam PF02687 FtsX-like permease family 674 764 4.2E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS05540 4919d5ee047d666a6839a22791b4ed7b 774 Pfam PF02687 FtsX-like permease family 282 375 7.4E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS05540 4919d5ee047d666a6839a22791b4ed7b 774 Gene3D G3DSA:1.20.1250.20 8 454 6.1E-5 T 29-03-2018 A616_RS25280 711e530df243b60a204ae1b62964871b 289 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 229 283 3.5E-20 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 A616_RS25280 711e530df243b60a204ae1b62964871b 289 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 21 223 6.8E-64 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS25280 711e530df243b60a204ae1b62964871b 289 PIRSF PIRSF006483 3 289 6.6E-88 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS08815 fa449822ea7e920e5b59dfd70a91e63c 406 Pfam PF00144 Beta-lactamase 11 387 7.6E-49 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS08815 fa449822ea7e920e5b59dfd70a91e63c 406 SUPERFAMILY SSF56601 4 387 1.07E-66 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS08815 fa449822ea7e920e5b59dfd70a91e63c 406 Gene3D G3DSA:3.40.710.10 1 395 2.0E-68 T 29-03-2018 A616_RS16835 9c0038f8a46fa418ebe3304e1a311347 473 Pfam PF06054 Competence protein CoiA-like family 3 186 1.2E-27 T 29-03-2018 IPR010330 Competence-induced protein CoiA-like A616_RS07165 45c1333f636f46277a828325b75acff8 118 Pfam PF10710 Protein of unknown function (DUF2512) 3 105 1.6E-17 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 A616_RS12660 69f225a2b6c49316aba91a6935b1cc86 508 Pfam PF03806 AbgT putative transporter family 17 506 7.4E-188 T 29-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 A616_RS25100 915df473cc83b9abea7764ea4f2d38ed 538 Gene3D G3DSA:3.10.450.40 24 88 0.11 T 29-03-2018 A616_RS05010 939b7babadef4e61ccdb1639a3a152ce 127 Gene3D G3DSA:1.10.10.10 25 124 2.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05010 939b7babadef4e61ccdb1639a3a152ce 127 SUPERFAMILY SSF46785 15 114 9.1E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05010 939b7babadef4e61ccdb1639a3a152ce 127 Pfam PF01638 HxlR-like helix-turn-helix 29 115 2.0E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS08785 c39ef9edb2001257e8c4cb22feff3159 121 SUPERFAMILY SSF142906 2 116 8.89E-40 T 29-03-2018 A616_RS08785 c39ef9edb2001257e8c4cb22feff3159 121 Pfam PF04237 YjbR 13 102 1.9E-26 T 29-03-2018 IPR007351 Uncharacterised protein YjbR A616_RS06345 aa7ef1ef9b01532780f968f7563958c6 476 PIRSF PIRSF019260 29 473 1.4E-62 T 29-03-2018 IPR016753 Phage portal protein PBSX family, Firmicutes A616_RS06345 aa7ef1ef9b01532780f968f7563958c6 476 Pfam PF04860 Phage portal protein 77 407 4.6E-13 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A616_RS00270 2373f2fa397136b64067be5a815449fb 339 SUPERFAMILY SSF52540 4 242 5.19E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00270 2373f2fa397136b64067be5a815449fb 339 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS00270 2373f2fa397136b64067be5a815449fb 339 Gene3D G3DSA:3.40.50.300 1 260 4.7E-82 T 29-03-2018 A616_RS00270 2373f2fa397136b64067be5a815449fb 339 SMART SM00382 28 211 2.9E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS00270 2373f2fa397136b64067be5a815449fb 339 Pfam PF00005 ABC transporter 19 161 7.1E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS00270 2373f2fa397136b64067be5a815449fb 339 SUPERFAMILY SSF50331 258 328 6.23E-5 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 Gene3D G3DSA:3.40.190.80 155 274 1.6E-31 T 29-03-2018 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 Pfam PF00459 Inositol monophosphatase family 11 260 7.3E-65 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR01959 SuhB family inositol monophosphatase signature 109 128 4.1E-6 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR01959 SuhB family inositol monophosphatase signature 203 215 4.1E-6 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 Gene3D G3DSA:3.30.540.10 4 154 1.5E-46 T 29-03-2018 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 213 237 3.4E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 3.4E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 182 203 3.4E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 135 158 3.4E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 3.4E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 3.4E-44 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A616_RS23895 91131e5b691fc58ccaa36877b104ebfe 274 SUPERFAMILY SSF56655 8 264 3.93E-79 T 29-03-2018 A616_RS13615 24df9fb5fc2b1068619f5b56672a838b 219 Pfam PF07486 Cell Wall Hydrolase 120 218 2.4E-28 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A616_RS00755 3ae65b74b75bd9304bf8701ad40937c8 102 Pfam PF04977 Septum formation initiator 26 102 4.2E-13 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 A616_RS12765 ca06b4b8a87b891526f6382408617384 107 Pfam PF02583 Metal-sensitive transcriptional repressor 26 104 4.7E-30 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A616_RS07790 8553710c635de470336221880ed151a6 82 Pfam PF00462 Glutaredoxin 5 60 1.2E-12 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A616_RS07790 8553710c635de470336221880ed151a6 82 SUPERFAMILY SSF52833 5 74 1.91E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS07790 8553710c635de470336221880ed151a6 82 Gene3D G3DSA:3.40.30.10 3 82 1.4E-17 T 29-03-2018 A616_RS04705 5189dbdbbec10429c5da7f0a27f46d5e 265 SUPERFAMILY SSF56317 1 257 3.4E-79 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS04705 5189dbdbbec10429c5da7f0a27f46d5e 265 Pfam PF00795 Carbon-nitrogen hydrolase 2 249 4.4E-67 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS04705 5189dbdbbec10429c5da7f0a27f46d5e 265 Gene3D G3DSA:3.60.110.10 1 264 4.1E-83 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS12760 b373024b1121a6e26903897268fbc7cd 208 SUPERFAMILY SSF56014 72 205 6.02E-27 T 29-03-2018 A616_RS12760 b373024b1121a6e26903897268fbc7cd 208 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 82 205 3.8E-17 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS12760 b373024b1121a6e26903897268fbc7cd 208 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 116 132 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A616_RS12760 b373024b1121a6e26903897268fbc7cd 208 Gene3D G3DSA:3.30.413.10 71 207 7.4E-23 T 29-03-2018 A616_RS02590 3635afc9f39d3c9f1243acf9fd50e063 396 Pfam PF01882 Protein of unknown function DUF58 203 284 4.4E-14 T 29-03-2018 IPR002881 Domain of unknown function DUF58 A616_RS19060 6a34e5ea7c75eed323ae334d35996d6e 121 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 18.584 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A616_RS19060 6a34e5ea7c75eed323ae334d35996d6e 121 TIGRFAM TIGR00494 crcB: protein CrcB 5 117 2.5E-26 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A616_RS19060 6a34e5ea7c75eed323ae334d35996d6e 121 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 113 2.0E-24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A616_RS19680 69eb8d9c333cb5adbbb981ca7400c12f 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 297 8.8E-42 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS19680 69eb8d9c333cb5adbbb981ca7400c12f 319 Gene3D G3DSA:1.10.3470.10 8 305 3.1E-50 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS22440 80c54cfdb20741b97ae9d07cce2ed9ad 689 Gene3D G3DSA:3.10.450.50 1 19 3.9E-10 T 29-03-2018 A616_RS22440 80c54cfdb20741b97ae9d07cce2ed9ad 689 Gene3D G3DSA:3.10.450.50 20 109 1.5E-8 T 29-03-2018 A616_RS22440 80c54cfdb20741b97ae9d07cce2ed9ad 689 Pfam PF02810 SEC-C motif 5 22 2.4E-9 T 29-03-2018 IPR004027 SEC-C motif A616_RS22440 80c54cfdb20741b97ae9d07cce2ed9ad 689 SUPERFAMILY SSF103642 2 23 9.97E-8 T 29-03-2018 A616_RS22440 80c54cfdb20741b97ae9d07cce2ed9ad 689 Gene3D G3DSA:1.10.150.130 474 585 3.7E-7 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 SUPERFAMILY SSF53474 5 283 4.32E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 Pfam PF00561 alpha/beta hydrolase fold 26 269 4.2E-27 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00412 Epoxide hydrolase signature 259 281 8.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00412 Epoxide hydrolase signature 112 125 8.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00412 Epoxide hydrolase signature 98 111 8.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00412 Epoxide hydrolase signature 227 243 8.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00412 Epoxide hydrolase signature 32 50 8.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 6.6E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 6.6E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS07585 fd19384d195aec1281b0d631d79badc6 294 Gene3D G3DSA:3.40.50.1820 4 287 3.3E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS00710 7681c22b6adeb77d54cf291a69f605e7 355 Gene3D G3DSA:3.10.50.40 198 326 9.2E-29 T 29-03-2018 A616_RS00710 7681c22b6adeb77d54cf291a69f605e7 355 Gene3D G3DSA:1.10.4030.10 60 190 0.007 T 29-03-2018 A616_RS00710 7681c22b6adeb77d54cf291a69f605e7 355 SUPERFAMILY SSF54534 210 308 2.29E-25 T 29-03-2018 A616_RS00710 7681c22b6adeb77d54cf291a69f605e7 355 SUPERFAMILY SSF109998 69 232 1.26E-5 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS00710 7681c22b6adeb77d54cf291a69f605e7 355 Pfam PF13616 PPIC-type PPIASE domain 206 307 2.6E-27 T 29-03-2018 A616_RS22630 35debd6df680dbd234b2bdaa658b96b3 376 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 17 182 1.6E-25 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 A616_RS22630 35debd6df680dbd234b2bdaa658b96b3 376 SUPERFAMILY SSF53756 89 374 9.74E-32 T 29-03-2018 A616_RS22630 35debd6df680dbd234b2bdaa658b96b3 376 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 224 316 9.2E-6 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS22630 35debd6df680dbd234b2bdaa658b96b3 376 Gene3D G3DSA:3.40.50.2000 199 371 1.1E-22 T 29-03-2018 A616_RS22630 35debd6df680dbd234b2bdaa658b96b3 376 Gene3D G3DSA:3.40.50.2000 2 198 4.1E-10 T 29-03-2018 A616_RS28620 f074b3cb95cfcb1f18a5b2f9ddea2e64 323 Gene3D G3DSA:1.10.3720.10 1 303 1.3E-44 T 29-03-2018 A616_RS28620 f074b3cb95cfcb1f18a5b2f9ddea2e64 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 1.5E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS28620 f074b3cb95cfcb1f18a5b2f9ddea2e64 323 SUPERFAMILY SSF161098 89 302 2.62E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS17080 a67973c85667d3ad96fa61f6c90b9cda 203 Gene3D G3DSA:3.40.630.30 38 199 2.7E-7 T 29-03-2018 A616_RS17080 a67973c85667d3ad96fa61f6c90b9cda 203 SUPERFAMILY SSF55729 106 187 3.6E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS08115 11bd5c9a28743b8536065fa04ccd3c16 213 Gene3D G3DSA:3.40.50.620 40 180 1.1E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A616_RS08115 11bd5c9a28743b8536065fa04ccd3c16 213 Pfam PF02698 DUF218 domain 54 184 3.2E-28 T 29-03-2018 IPR003848 Domain of unknown function DUF218 A616_RS02615 47a4db145c30c4b0919167e390ecdcdb 103 Pfam PF00581 Rhodanese-like domain 9 97 3.4E-14 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS02615 47a4db145c30c4b0919167e390ecdcdb 103 SMART SM00450 9 103 1.5E-21 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS02615 47a4db145c30c4b0919167e390ecdcdb 103 Gene3D G3DSA:3.40.250.10 2 103 2.3E-26 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS02615 47a4db145c30c4b0919167e390ecdcdb 103 SUPERFAMILY SSF52821 3 98 1.24E-32 T 29-03-2018 IPR001763 Rhodanese-like domain A616_RS10840 0e115895ea0e4bbe7aedcc6f1d824b78 86 PIRSF PIRSF037258 1 86 2.2E-39 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 A616_RS10840 0e115895ea0e4bbe7aedcc6f1d824b78 86 Hamap MF_01507 UPF0297 protein . 1 85 25.54 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 A616_RS10840 0e115895ea0e4bbe7aedcc6f1d824b78 86 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 3.8E-35 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 A616_RS03850 e7354fad504a24ec1b8e93b07b3f18e2 499 PIRSF PIRSF005690 9 498 6.0E-182 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS03850 e7354fad504a24ec1b8e93b07b3f18e2 499 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 21 484 6.3E-188 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS23850 78aabcc73ff7685c0b78aadf66d00fb3 238 SUPERFAMILY SSF52266 32 227 1.83E-41 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS23850 78aabcc73ff7685c0b78aadf66d00fb3 238 Gene3D G3DSA:3.40.50.1110 19 228 2.4E-30 T 29-03-2018 A616_RS23850 78aabcc73ff7685c0b78aadf66d00fb3 238 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 45 218 2.6E-23 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS21585 515162313218aaa55280b3bbddd9fea2 645 SUPERFAMILY SSF81665 421 641 1.96E-5 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A616_RS21585 515162313218aaa55280b3bbddd9fea2 645 Gene3D G3DSA:3.20.20.70 2 337 4.0E-32 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS21585 515162313218aaa55280b3bbddd9fea2 645 SUPERFAMILY SSF51395 7 329 1.4E-39 T 29-03-2018 A616_RS21585 515162313218aaa55280b3bbddd9fea2 645 Pfam PF01180 Dihydroorotate dehydrogenase 55 329 1.3E-19 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A616_RS04240 d2af2ced460b6b80131f71f1180edcde 539 SUPERFAMILY SSF101898 12 165 1.83E-9 T 29-03-2018 A616_RS04240 d2af2ced460b6b80131f71f1180edcde 539 Gene3D G3DSA:3.90.1720.10 383 539 3.5E-10 T 29-03-2018 A616_RS04240 d2af2ced460b6b80131f71f1180edcde 539 Gene3D G3DSA:2.120.10.30 50 232 7.2E-9 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS02640 344c0dfe7b04575d98db80d37f3d6a85 142 Pfam PF06491 Disulphide isomerase 7 141 1.6E-59 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A616_RS02640 344c0dfe7b04575d98db80d37f3d6a85 142 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 141 4.7E-63 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family A616_RS22180 783ff974684601c4c651abef217fe24d 151 Pfam PF13673 Acetyltransferase (GNAT) domain 30 148 2.7E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS22180 783ff974684601c4c651abef217fe24d 151 SUPERFAMILY SSF55729 2 149 1.49E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS22180 783ff974684601c4c651abef217fe24d 151 Gene3D G3DSA:3.40.630.30 1 151 2.4E-37 T 29-03-2018 A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 SUPERFAMILY SSF52540 5 253 1.82E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 Gene3D G3DSA:3.40.50.300 2 320 3.9E-86 T 29-03-2018 A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 1.3E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 Pfam PF00005 ABC transporter 32 181 4.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 SMART SM00382 40 231 1.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS28370 5a1ca83347145a7e49bcb741b9706d53 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 1.8E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A616_RS13705 2230c550490db859d35c2869f0b76c3f 115 Gene3D G3DSA:3.10.20.30 2 115 2.1E-22 T 29-03-2018 IPR012675 Beta-grasp domain A616_RS13705 2230c550490db859d35c2869f0b76c3f 115 SUPERFAMILY SSF54292 3 93 1.32E-19 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS13705 2230c550490db859d35c2869f0b76c3f 115 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 81 3.4E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A616_RS04310 8c92d225cbb0a769656e9c48bf142b33 437 Gene3D G3DSA:2.60.40.1240 292 430 1.6E-7 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain A616_RS24185 6ed5df70ea7214459fd8a90839a91f10 189 Pfam PF13302 Acetyltransferase (GNAT) domain 10 156 2.4E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS24185 6ed5df70ea7214459fd8a90839a91f10 189 Gene3D G3DSA:3.40.630.30 2 189 1.6E-26 T 29-03-2018 A616_RS24185 6ed5df70ea7214459fd8a90839a91f10 189 SUPERFAMILY SSF55729 2 182 8.73E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS26975 fe1d89367edfdcea088d2fe77b5bebf5 555 Pfam PF16949 Putative ATP-binding cassette 75 475 1.2E-16 T 29-03-2018 IPR031599 Putative ATP-binding cassette A616_RS27985 de9f6b05890c4eebac7a986bc0725f39 346 Pfam PF01757 Acyltransferase family 15 318 1.8E-11 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS30765 99904d04a9da8a86e7e7d23fc7eb096a 161 Pfam PF00936 BMC domain 7 82 6.8E-25 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30765 99904d04a9da8a86e7e7d23fc7eb096a 161 SMART SM00877 6 82 1.3E-28 T 29-03-2018 IPR000249 Microcompartment protein, bacteria A616_RS30765 99904d04a9da8a86e7e7d23fc7eb096a 161 SUPERFAMILY SSF143414 7 93 4.97E-27 T 29-03-2018 A616_RS23295 d72a822aacb8931178458731d2fa5af3 477 Pfam PF13699 Domain of unknown function (DUF4157) 77 150 2.7E-27 T 29-03-2018 IPR025295 Domain of unknown function DUF4157 A616_RS02870 1cffb12ad081966ee11da7f414a33c59 468 Gene3D G3DSA:1.10.3910.10 60 122 0.11 T 29-03-2018 A616_RS02870 1cffb12ad081966ee11da7f414a33c59 468 Gene3D G3DSA:1.10.3910.10 267 317 0.49 T 29-03-2018 A616_RS02870 1cffb12ad081966ee11da7f414a33c59 468 Gene3D G3DSA:1.10.260.40 168 223 0.06 T 29-03-2018 A616_RS06505 7705c27038dbdfab48c56b303be452d4 117 Pfam PF08863 YolD-like protein 19 116 1.3E-17 T 29-03-2018 IPR014962 YolD-like protein A616_RS10250 31a4328163baa8c0c62b772d73e215d7 143 Gene3D G3DSA:2.130.10.10 89 139 0.001 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A616_RS07440 508ff8c5b14f69fa95fef2340b2d3b6b 349 PIRSF PIRSF006470 27 348 3.3E-114 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A616_RS07440 508ff8c5b14f69fa95fef2340b2d3b6b 349 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 49 303 1.5E-83 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A616_RS07440 508ff8c5b14f69fa95fef2340b2d3b6b 349 Gene3D G3DSA:3.40.190.10 35 289 0.009 T 29-03-2018 A616_RS07440 508ff8c5b14f69fa95fef2340b2d3b6b 349 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 330 1.1E-92 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 SUPERFAMILY SSF51621 5 426 1.03E-158 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 10 249 2.7E-104 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 Gene3D G3DSA:3.20.20.60 2 409 2.6E-151 T 29-03-2018 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 PIRSF PIRSF001362 1 429 2.9E-240 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 ProSitePatterns PS00161 Isocitrate lyase signature. 187 192 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 Pfam PF00463 Isocitrate lyase family 250 426 7.5E-50 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A616_RS00245 2a0ea17a4ec0837709116fc2bdc27b93 429 Pfam PF00463 Isocitrate lyase family 10 249 2.6E-56 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A616_RS29460 8770fb91d2f42a29cf6cfc4768ba8afb 118 Gene3D G3DSA:3.30.160.170 16 114 1.9E-27 T 29-03-2018 IPR005186 FlaG protein A616_RS29460 8770fb91d2f42a29cf6cfc4768ba8afb 118 SUPERFAMILY SSF160214 30 117 1.06E-27 T 29-03-2018 IPR005186 FlaG protein A616_RS29460 8770fb91d2f42a29cf6cfc4768ba8afb 118 Pfam PF03646 FlaG protein 26 116 3.3E-26 T 29-03-2018 IPR005186 FlaG protein A616_RS27310 4991c62e759ef71e7b891dc720415acb 252 Gene3D G3DSA:3.40.50.300 1 251 2.9E-70 T 29-03-2018 A616_RS27310 4991c62e759ef71e7b891dc720415acb 252 Pfam PF00005 ABC transporter 21 164 1.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27310 4991c62e759ef71e7b891dc720415acb 252 SMART SM00382 29 226 3.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS27310 4991c62e759ef71e7b891dc720415acb 252 SUPERFAMILY SSF52540 4 226 3.37E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27310 4991c62e759ef71e7b891dc720415acb 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS07160 cc6130194f02cab5073f7a2dd22acddb 172 Pfam PF11553 Protein of unknown function (DUF3231) 2 165 1.3E-35 T 29-03-2018 IPR021617 Protein of unknown function DUF3231 A616_RS07160 cc6130194f02cab5073f7a2dd22acddb 172 Gene3D G3DSA:1.20.1260.10 1 156 2.3E-28 T 29-03-2018 IPR012347 Ferritin-related A616_RS21355 9d630349dcbe8180354afa87930265f4 420 PIRSF PIRSF006060 1 418 2.5E-70 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS21355 9d630349dcbe8180354afa87930265f4 420 Pfam PF13520 Amino acid permease 17 404 3.8E-42 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS14130 1d1e854c93d0de011d1a88cdd4b3bea0 115 Pfam PF00085 Thioredoxin 5 103 5.5E-21 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 A616_RS14130 1d1e854c93d0de011d1a88cdd4b3bea0 115 Gene3D G3DSA:3.40.30.10 1 115 5.5E-29 T 29-03-2018 A616_RS14130 1d1e854c93d0de011d1a88cdd4b3bea0 115 SUPERFAMILY SSF52833 2 106 6.24E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS13510 89ca47bdddde3e2d5793b55e66e55065 409 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 54 407 1.5E-76 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 A616_RS13510 89ca47bdddde3e2d5793b55e66e55065 409 Pfam PF01578 Cytochrome C assembly protein 78 404 2.3E-36 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A616_RS20350 4a9bcca8f7ccbc34ad06b1bbf94de578 411 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 10 352 2.4E-100 T 29-03-2018 IPR014226 Sporulation integral membrane protein YlbJ A616_RS15705 d6aef7bff65b35cedfb8f16ec87ce1a2 225 Gene3D G3DSA:3.40.630.30 71 213 3.7E-5 T 29-03-2018 A616_RS15705 d6aef7bff65b35cedfb8f16ec87ce1a2 225 SUPERFAMILY SSF55729 133 220 4.06E-6 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS15705 d6aef7bff65b35cedfb8f16ec87ce1a2 225 Pfam PF12746 GNAT acetyltransferase 135 216 6.9E-10 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like A616_RS30520 860fe54c308702e82058254c954adf5a 241 Pfam PF01048 Phosphorylase superfamily 14 231 1.7E-39 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS30520 860fe54c308702e82058254c954adf5a 241 Gene3D G3DSA:3.40.50.1580 8 239 6.0E-49 T 29-03-2018 A616_RS30520 860fe54c308702e82058254c954adf5a 241 SUPERFAMILY SSF53167 5 238 1.96E-59 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A616_RS17990 1432ade24f6a38c427182d70711fbcf1 226 Gene3D G3DSA:1.20.910.10 1 225 1.6E-62 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A616_RS17990 1432ade24f6a38c427182d70711fbcf1 226 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 12 217 1.6E-64 T 29-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 A616_RS17990 1432ade24f6a38c427182d70711fbcf1 226 SUPERFAMILY SSF48613 2 216 8.31E-72 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A616_RS17990 1432ade24f6a38c427182d70711fbcf1 226 Pfam PF03070 TENA/THI-4/PQQC family 10 217 1.1E-51 T 29-03-2018 IPR004305 Thiaminase-2/PQQC A616_RS11885 9e09f377fa8ea4d851dbeb80b57b3742 59 Pfam PF08671 Anti-repressor SinI 11 36 6.9E-10 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A616_RS11885 9e09f377fa8ea4d851dbeb80b57b3742 59 SUPERFAMILY SSF47406 10 37 1.1E-8 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 A616_RS16340 45f3d957fad5dfe4c6a505e4e6bb8433 250 Gene3D G3DSA:3.90.550.10 1 233 2.3E-12 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS16340 45f3d957fad5dfe4c6a505e4e6bb8433 250 Pfam PF00535 Glycosyl transferase family 2 34 131 2.9E-8 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS16340 45f3d957fad5dfe4c6a505e4e6bb8433 250 SUPERFAMILY SSF53448 23 130 3.58E-12 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS24635 b7676171488d13558bf4bf9f9223a356 359 Gene3D G3DSA:3.20.20.70 3 359 2.7E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS24635 b7676171488d13558bf4bf9f9223a356 359 SUPERFAMILY SSF51412 103 349 6.56E-68 T 29-03-2018 A616_RS24635 b7676171488d13558bf4bf9f9223a356 359 SUPERFAMILY SSF51412 3 76 6.56E-68 T 29-03-2018 A616_RS24635 b7676171488d13558bf4bf9f9223a356 359 Pfam PF03060 Nitronate monooxygenase 10 346 3.1E-98 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 A616_RS00570 3b1b6ed9228874c8938e8332889b5f04 109 SUPERFAMILY SSF54913 1 107 7.04E-10 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A616_RS00570 3b1b6ed9228874c8938e8332889b5f04 109 Pfam PF06153 Cyclic-di-AMP receptor 1 108 8.5E-48 T 29-03-2018 IPR010375 Cyclic-di-AMP receptor A616_RS00570 3b1b6ed9228874c8938e8332889b5f04 109 Gene3D G3DSA:3.30.70.120 1 109 1.8E-12 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A616_RS25460 b786b3a447d6db40948a7e3277e47571 168 Pfam PF13302 Acetyltransferase (GNAT) domain 5 144 4.2E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25460 b786b3a447d6db40948a7e3277e47571 168 Gene3D G3DSA:3.40.630.30 2 150 4.4E-11 T 29-03-2018 A616_RS25460 b786b3a447d6db40948a7e3277e47571 168 SUPERFAMILY SSF55729 4 146 7.53E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS01540 4347089f74e927c6b3851d4a89bfe663 119 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 119 28.604 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01540 4347089f74e927c6b3851d4a89bfe663 119 Pfam PF01196 Ribosomal protein L17 16 119 7.1E-41 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01540 4347089f74e927c6b3851d4a89bfe663 119 SUPERFAMILY SSF64263 2 119 1.7E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01540 4347089f74e927c6b3851d4a89bfe663 119 TIGRFAM TIGR00059 L17: ribosomal protein bL17 4 119 2.4E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01540 4347089f74e927c6b3851d4a89bfe663 119 Gene3D G3DSA:3.90.1030.10 1 119 1.5E-48 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS01540 4347089f74e927c6b3851d4a89bfe663 119 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS04770 df05d976765504066773b47154453991 228 Gene3D G3DSA:3.40.50.150 3 195 4.6E-27 T 29-03-2018 A616_RS04770 df05d976765504066773b47154453991 228 Pfam PF08241 Methyltransferase domain 42 146 1.1E-17 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS04770 df05d976765504066773b47154453991 228 SUPERFAMILY SSF53335 5 182 1.37E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS16300 c6fc2b6a42b57ba5a1937275c382ece7 80 Hamap MF_01103 UPF0291 protein . 1 58 14.44 T 29-03-2018 IPR009242 Protein of unknown function DUF896 A616_RS16300 c6fc2b6a42b57ba5a1937275c382ece7 80 Gene3D G3DSA:1.10.287.540 3 54 1.6E-20 T 29-03-2018 A616_RS16300 c6fc2b6a42b57ba5a1937275c382ece7 80 SUPERFAMILY SSF158221 3 40 7.19E-13 T 29-03-2018 A616_RS16300 c6fc2b6a42b57ba5a1937275c382ece7 80 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 66 8.6E-27 T 29-03-2018 IPR009242 Protein of unknown function DUF896 A616_RS14260 9b4286372dd15832c10f950484080b2d 285 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 149 169 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A616_RS14260 9b4286372dd15832c10f950484080b2d 285 Gene3D G3DSA:3.60.110.10 1 285 1.1E-54 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS14260 9b4286372dd15832c10f950484080b2d 285 SUPERFAMILY SSF56317 2 281 3.01E-56 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS14260 9b4286372dd15832c10f950484080b2d 285 Pfam PF00795 Carbon-nitrogen hydrolase 4 233 2.2E-28 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 SUPERFAMILY SSF53448 271 387 1.41E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 Gene3D G3DSA:3.90.550.10 16 259 2.0E-14 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 Gene3D G3DSA:3.90.550.10 260 367 1.2E-20 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 SUPERFAMILY SSF48452 458 614 2.28E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 Pfam PF00535 Glycosyl transferase family 2 273 357 9.5E-17 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 SUPERFAMILY SSF53448 19 252 7.03E-15 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31665 b0dc6bcffa84a07890eb61b9cbff42b6 623 Gene3D G3DSA:1.25.40.10 410 617 8.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS17555 2f1b260ee81316e0b8cb1c66723c4ab2 46 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 12 44 4.8E-7 T 29-03-2018 IPR009229 Staphylococcal AgrD A616_RS07700 3914a633cea04243ea2fb118be337abc 197 Gene3D G3DSA:1.10.1660.10 12 187 1.0E-12 T 29-03-2018 A616_RS10875 688150f9dc5d5e5c9e46d01f623ff297 163 SUPERFAMILY SSF102712 2 138 8.5E-9 T 29-03-2018 A616_RS10875 688150f9dc5d5e5c9e46d01f623ff297 163 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 124 1.8E-11 T 29-03-2018 IPR028090 JAB domain, prokaryotic A616_RS10875 688150f9dc5d5e5c9e46d01f623ff297 163 Gene3D G3DSA:3.40.140.10 1 155 2.0E-12 T 29-03-2018 A616_RS08895 95535d3342274e7b465fecb3ab93e7e8 231 Pfam PF03741 Integral membrane protein TerC family 17 186 9.2E-44 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 A616_RS08895 95535d3342274e7b465fecb3ab93e7e8 231 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 14 187 2.7E-66 T 29-03-2018 IPR022301 Integral membrane protein YjbE A616_RS21300 ef88df909ace531daf82e4214b29d2d9 364 Pfam PF01098 Cell cycle protein 12 363 1.5E-117 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A616_RS21300 ef88df909ace531daf82e4214b29d2d9 364 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 361 1.8E-122 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A616_RS21300 ef88df909ace531daf82e4214b29d2d9 364 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A616_RS21300 ef88df909ace531daf82e4214b29d2d9 364 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 361 1.2E-152 T 29-03-2018 IPR013438 Sporulation stage V, protein E A616_RS16625 dcf79eabd8c572d8d3aa579677e5ab80 239 Gene3D G3DSA:3.40.1800.10 113 205 2.1E-10 T 29-03-2018 A616_RS16625 dcf79eabd8c572d8d3aa579677e5ab80 239 Pfam PF01844 HNH endonuclease 146 191 2.2E-5 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A616_RS10690 11e2d29a10eb5e349e88a279bd10ef46 138 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 7 118 6.4E-28 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane A616_RS10690 11e2d29a10eb5e349e88a279bd10ef46 138 Pfam PF12670 Protein of unknown function (DUF3792) 6 116 1.7E-21 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane A616_RS22475 bc2dd833d8edb959a7cec96bdaa6ebd6 161 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 7 149 1.0E-27 T 29-03-2018 IPR018639 Domain of unknown function DUF2062 A616_RS23635 434351a775a960daae1b12d996da270f 310 SUPERFAMILY SSF51430 4 309 4.19E-96 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS23635 434351a775a960daae1b12d996da270f 310 Gene3D G3DSA:3.20.20.100 1 310 4.1E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS23635 434351a775a960daae1b12d996da270f 310 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 142 159 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A616_RS23635 434351a775a960daae1b12d996da270f 310 PRINTS PR00069 Aldo-keto reductase signature 111 129 1.5E-16 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23635 434351a775a960daae1b12d996da270f 310 PRINTS PR00069 Aldo-keto reductase signature 242 266 1.5E-16 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23635 434351a775a960daae1b12d996da270f 310 PRINTS PR00069 Aldo-keto reductase signature 45 69 1.5E-16 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23635 434351a775a960daae1b12d996da270f 310 PRINTS PR00069 Aldo-keto reductase signature 142 159 1.5E-16 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A616_RS23635 434351a775a960daae1b12d996da270f 310 Pfam PF00248 Aldo/keto reductase family 16 308 1.6E-74 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS24120 147cf274e63e3f18cc3341f4f7e19343 279 SUPERFAMILY SSF53474 5 275 2.49E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24120 147cf274e63e3f18cc3341f4f7e19343 279 Gene3D G3DSA:3.40.50.1820 1 276 3.5E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS06855 3a04f45e3cd6a77b6079e28eb754e5d1 313 SUPERFAMILY SSF56281 57 311 6.42E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS06855 3a04f45e3cd6a77b6079e28eb754e5d1 313 PIRSF PIRSF038896 29 312 2.2E-63 T 29-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 A616_RS06855 3a04f45e3cd6a77b6079e28eb754e5d1 313 Pfam PF12706 Beta-lactamase superfamily domain 74 271 7.0E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS06855 3a04f45e3cd6a77b6079e28eb754e5d1 313 Gene3D G3DSA:3.60.15.10 29 313 1.0E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS06555 583ea3d6f4befb7ab55719d928cd9701 496 SUPERFAMILY SSF58104 198 489 1.57E-51 T 29-03-2018 A616_RS06555 583ea3d6f4befb7ab55719d928cd9701 496 Gene3D G3DSA:1.10.287.950 241 453 5.3E-44 T 29-03-2018 A616_RS06555 583ea3d6f4befb7ab55719d928cd9701 496 SMART SM00283 227 474 5.8E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS06555 583ea3d6f4befb7ab55719d928cd9701 496 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 300 455 4.6E-33 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS25975 1f25a94d6de765312f81a0b77896941c 323 Hamap MF_00313 Glutaminase [glsA]. 9 323 43.7 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS25975 1f25a94d6de765312f81a0b77896941c 323 TIGRFAM TIGR03814 Gln_ase: glutaminase A 13 323 9.2E-117 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS25975 1f25a94d6de765312f81a0b77896941c 323 Pfam PF04960 Glutaminase 27 323 7.1E-108 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A616_RS25975 1f25a94d6de765312f81a0b77896941c 323 SUPERFAMILY SSF56601 8 323 3.82E-114 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS25975 1f25a94d6de765312f81a0b77896941c 323 Gene3D G3DSA:3.40.710.10 4 323 4.1E-117 T 29-03-2018 A616_RS31920 1cdf4bb71bb8f0bb0dc873483ac93c34 295 Gene3D G3DSA:3.40.50.720 3 295 6.0E-27 T 29-03-2018 A616_RS31920 1cdf4bb71bb8f0bb0dc873483ac93c34 295 SUPERFAMILY SSF51735 2 292 1.82E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS31920 1cdf4bb71bb8f0bb0dc873483ac93c34 295 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 5 290 3.1E-82 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 A616_RS31920 1cdf4bb71bb8f0bb0dc873483ac93c34 295 Pfam PF08338 Domain of unknown function (DUF1731) 245 293 9.2E-12 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 A616_RS31920 1cdf4bb71bb8f0bb0dc873483ac93c34 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 217 4.1E-13 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS26930 88e0251bb3436a9a86d8cb5516402809 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 350 1.3E-72 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS26930 88e0251bb3436a9a86d8cb5516402809 366 Pfam PF03845 Spore germination protein 8 323 4.6E-62 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 Gene3D G3DSA:3.90.1150.10 261 367 2.3E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 Gene3D G3DSA:3.40.640.10 22 260 2.4E-28 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 372 194.98 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 9 368 4.6E-179 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 12 366 5.2E-154 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 PIRSF PIRSF000524 4 368 1.6E-59 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 SUPERFAMILY SSF53383 10 366 1.29E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS24685 ed664cc5a8bcf9415386de7e3c7f1b8e 372 Pfam PF00266 Aminotransferase class-V 40 320 3.8E-27 T 29-03-2018 IPR000192 Aminotransferase class V domain A616_RS29745 58475189b97c841f6daf5659054783c7 1050 Pfam PF00395 S-layer homology domain 35 72 2.4E-7 T 29-03-2018 IPR001119 S-layer homology domain A616_RS29745 58475189b97c841f6daf5659054783c7 1050 Pfam PF00395 S-layer homology domain 93 135 5.4E-13 T 29-03-2018 IPR001119 S-layer homology domain A616_RS13500 e3b984a502643d019493655758ee8799 174 ProSitePatterns PS00194 Thioredoxin family active site. 66 84 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A616_RS13500 e3b984a502643d019493655758ee8799 174 SUPERFAMILY SSF52833 10 173 1.43E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS13500 e3b984a502643d019493655758ee8799 174 Pfam PF00578 AhpC/TSA family 38 154 1.7E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS13500 e3b984a502643d019493655758ee8799 174 Gene3D G3DSA:3.40.30.10 29 173 2.8E-41 T 29-03-2018 A616_RS00950 13b3d918ff5fd5dd39bd45da02ef4a03 467 SUPERFAMILY SSF52172 3 119 8.54E-10 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS00950 13b3d918ff5fd5dd39bd45da02ef4a03 467 Gene3D G3DSA:3.40.50.2300 1 164 2.8E-7 T 29-03-2018 A616_RS00950 13b3d918ff5fd5dd39bd45da02ef4a03 467 SUPERFAMILY SSF52540 166 232 2.82E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00950 13b3d918ff5fd5dd39bd45da02ef4a03 467 SUPERFAMILY SSF52540 267 440 2.82E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS00950 13b3d918ff5fd5dd39bd45da02ef4a03 467 Gene3D G3DSA:3.40.50.300 165 450 5.3E-34 T 29-03-2018 A616_RS00950 13b3d918ff5fd5dd39bd45da02ef4a03 467 Pfam PF13614 AAA domain 166 364 7.8E-11 T 29-03-2018 IPR025669 AAA domain A616_RS12840 c92c2a437802ffe8cc3b36150f27a18e 146 Pfam PF14343 PrcB C-terminal 78 134 4.2E-15 T 29-03-2018 IPR025748 PrcB C-terminal domain A616_RS27695 06e904fcfb08aeb9a926388ee01d92cd 140 ProDom PD082409 MEMBRANE YVAD TRANSMEMBRANE 12 114 2.0E-32 T 29-03-2018 IPR020348 Uncharacterised protein family YvaD A616_RS27695 06e904fcfb08aeb9a926388ee01d92cd 140 Pfam PF17314 Family of unknown function (DUF5360) 11 132 2.2E-56 T 29-03-2018 IPR020348 Uncharacterised protein family YvaD A616_RS20850 bd0c1f079198c912de1ca4407dad4ffa 391 Pfam PF02515 CoA-transferase family III 2 330 1.4E-82 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 A616_RS20850 bd0c1f079198c912de1ca4407dad4ffa 391 SUPERFAMILY SSF89796 1 386 2.35E-92 T 29-03-2018 IPR023606 CoA-transferase family III domain A616_RS20850 bd0c1f079198c912de1ca4407dad4ffa 391 Gene3D G3DSA:3.40.50.10540 1 390 2.5E-89 T 29-03-2018 IPR023606 CoA-transferase family III domain A616_RS23035 3cd957f3718d8f5d5183673a92b82d99 364 Pfam PF14398 YheC/D like ATP-grasp 97 354 3.3E-78 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS23035 3cd957f3718d8f5d5183673a92b82d99 364 Gene3D G3DSA:3.30.1490.20 127 201 2.1E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS23035 3cd957f3718d8f5d5183673a92b82d99 364 SUPERFAMILY SSF56059 120 168 5.3E-17 T 29-03-2018 A616_RS23035 3cd957f3718d8f5d5183673a92b82d99 364 SUPERFAMILY SSF56059 196 344 5.3E-17 T 29-03-2018 A616_RS23035 3cd957f3718d8f5d5183673a92b82d99 364 Gene3D G3DSA:3.30.470.20 202 338 1.3E-15 T 29-03-2018 A616_RS12380 eaa8ca3d12a414ccc16e7fa7e9c55333 246 PIRSF PIRSF039085 4 246 2.6E-118 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS12380 eaa8ca3d12a414ccc16e7fa7e9c55333 246 SUPERFAMILY SSF52540 7 241 5.06E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS12380 eaa8ca3d12a414ccc16e7fa7e9c55333 246 Pfam PF00005 ABC transporter 23 171 1.4E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12380 eaa8ca3d12a414ccc16e7fa7e9c55333 246 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS12380 eaa8ca3d12a414ccc16e7fa7e9c55333 246 Gene3D G3DSA:3.40.50.300 4 245 2.6E-80 T 29-03-2018 A616_RS12380 eaa8ca3d12a414ccc16e7fa7e9c55333 246 SMART SM00382 32 236 4.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS14630 e018603bef7c7cc2695f37073f9694ab 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 225 2.7E-66 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS14630 e018603bef7c7cc2695f37073f9694ab 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 2.1E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 A616_RS14630 e018603bef7c7cc2695f37073f9694ab 294 PIRSF PIRSF006483 5 293 2.5E-96 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS21090 14b8b47227d272c8e82242b21d35e200 261 Pfam PF14042 Domain of unknown function (DUF4247) 19 201 3.1E-33 T 29-03-2018 IPR025341 Protein of unknown function DUF4247 A616_RS02795 a0cd2477a142b744e0225511eff5d986 112 Pfam PF01638 HxlR-like helix-turn-helix 26 109 1.8E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS02795 a0cd2477a142b744e0225511eff5d986 112 SUPERFAMILY SSF46785 13 111 5.38E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02795 a0cd2477a142b744e0225511eff5d986 112 Gene3D G3DSA:1.10.10.10 9 112 6.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31395 a7cc460625b1505542935f86db85b582 594 Pfam PF03239 Iron permease FTR1 family 336 540 3.4E-21 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.4E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 Gene3D G3DSA:3.40.190.10 86 172 9.3E-23 T 29-03-2018 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 SUPERFAMILY SSF46785 2 107 1.14E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 Gene3D G3DSA:3.40.190.10 173 263 4.7E-28 T 29-03-2018 A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 Gene3D G3DSA:1.10.10.10 1 83 2.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 Pfam PF03466 LysR substrate binding domain 84 290 1.8E-54 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS27235 c34c3355ecc4c647ecc6b0ecc38961b2 295 SUPERFAMILY SSF53850 85 292 1.33E-51 T 29-03-2018 A616_RS26100 db752aea360be9f593832dc1402d5dbd 180 Pfam PF01814 Hemerythrin HHE cation binding domain 25 162 1.0E-16 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A616_RS26100 db752aea360be9f593832dc1402d5dbd 180 Gene3D G3DSA:1.20.120.520 20 180 2.7E-23 T 29-03-2018 A616_RS03765 7ec16545b63ab9ed567a922d6f3dae18 1011 SUPERFAMILY SSF51261 79 220 4.76E-34 T 29-03-2018 IPR011055 Duplicated hybrid motif A616_RS03765 7ec16545b63ab9ed567a922d6f3dae18 1011 Pfam PF01551 Peptidase family M23 98 216 2.1E-24 T 29-03-2018 IPR016047 Peptidase M23 A616_RS03765 7ec16545b63ab9ed567a922d6f3dae18 1011 Gene3D G3DSA:2.70.70.10 47 223 4.2E-35 T 29-03-2018 A616_RS10225 e0d7c6f6db3bbad57288b122f2a68c14 186 Pfam PF07291 Methylamine utilisation protein MauE 7 155 1.1E-18 T 29-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 A616_RS15630 6631283e7317c868cc22816a1f68d37b 406 Gene3D G3DSA:1.20.1250.20 191 386 2.8E-14 T 29-03-2018 A616_RS15630 6631283e7317c868cc22816a1f68d37b 406 SUPERFAMILY SSF103473 3 382 2.75E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS15630 6631283e7317c868cc22816a1f68d37b 406 Gene3D G3DSA:1.20.1250.20 1 190 2.1E-25 T 29-03-2018 A616_RS15630 6631283e7317c868cc22816a1f68d37b 406 Pfam PF07690 Major Facilitator Superfamily 12 321 2.1E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS12770 a9f6dcd4965379804d8645c9517db963 248 Gene3D G3DSA:3.40.50.10320 14 246 3.8E-21 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS12770 a9f6dcd4965379804d8645c9517db963 248 SUPERFAMILY SSF102588 17 179 4.32E-19 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS18220 c86d8873dd42e0b3d4ac244e8d55bc7c 72 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 72 25.751 T 29-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like A616_RS18220 c86d8873dd42e0b3d4ac244e8d55bc7c 72 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 2 70 5.9E-28 T 29-03-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like A616_RS17505 38859210a28eae4f7d76a17baf83a018 222 SUPERFAMILY SSF49785 10 145 4.68E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS17505 38859210a28eae4f7d76a17baf83a018 222 Gene3D G3DSA:2.60.120.260 10 162 2.6E-18 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS17505 38859210a28eae4f7d76a17baf83a018 222 Pfam PF00754 F5/8 type C domain 32 143 4.2E-7 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain A616_RS00455 07dda2ccce50b98bfdb2f7c32e1dc5d3 161 Gene3D G3DSA:3.40.1260.10 1 161 8.2E-54 T 29-03-2018 A616_RS00455 07dda2ccce50b98bfdb2f7c32e1dc5d3 161 SUPERFAMILY SSF75169 8 53 2.22E-22 T 29-03-2018 IPR027396 DsrEFH-like A616_RS00455 07dda2ccce50b98bfdb2f7c32e1dc5d3 161 SUPERFAMILY SSF75169 103 156 2.22E-22 T 29-03-2018 IPR027396 DsrEFH-like A616_RS00455 07dda2ccce50b98bfdb2f7c32e1dc5d3 161 Pfam PF13686 DsrE/DsrF/DrsH-like family 6 160 1.9E-68 T 29-03-2018 IPR032836 DsrE2-like family A616_RS05310 fc2355026d14486a4334a79535d7b675 312 SUPERFAMILY SSF103481 205 296 1.83E-14 T 29-03-2018 A616_RS05310 fc2355026d14486a4334a79535d7b675 312 SUPERFAMILY SSF103481 45 142 7.06E-14 T 29-03-2018 A616_RS05310 fc2355026d14486a4334a79535d7b675 312 Pfam PF00892 EamA-like transporter family 155 292 1.4E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS05310 fc2355026d14486a4334a79535d7b675 312 Pfam PF00892 EamA-like transporter family 11 142 1.0E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS25970 d81a9f7f8776186e338c7b33e45052f2 721 Gene3D G3DSA:1.20.190.10 51 279 2.8E-44 T 29-03-2018 A616_RS25970 d81a9f7f8776186e338c7b33e45052f2 721 Gene3D G3DSA:2.60.120.260 437 620 7.2E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS25970 d81a9f7f8776186e338c7b33e45052f2 721 Pfam PF03944 delta endotoxin 469 614 8.4E-21 T 29-03-2018 IPR005638 Pesticidal crystal protein, C-terminal GO:0090729 A616_RS25970 d81a9f7f8776186e338c7b33e45052f2 721 SUPERFAMILY SSF49785 468 615 6.8E-18 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS25970 d81a9f7f8776186e338c7b33e45052f2 721 SUPERFAMILY SSF56849 52 279 1.83E-40 T 29-03-2018 IPR005639 Pesticidal crystal protein, N-terminal GO:0009405|GO:0090729 A616_RS25970 d81a9f7f8776186e338c7b33e45052f2 721 Pfam PF03945 delta endotoxin, N-terminal domain 73 279 4.0E-69 T 29-03-2018 IPR005639 Pesticidal crystal protein, N-terminal GO:0009405|GO:0090729 A616_RS17955 1cdfd9559e4ac18c551dee61c53bebf6 249 Pfam PF12730 ABC-2 family transporter protein 4 180 1.3E-18 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS05015 d088efce8c900178d4a83c437a5ab9a9 272 Pfam PF12146 Serine aminopeptidase, S33 37 149 2.2E-14 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 A616_RS05015 d088efce8c900178d4a83c437a5ab9a9 272 SUPERFAMILY SSF53474 8 263 1.35E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS05015 d088efce8c900178d4a83c437a5ab9a9 272 Gene3D G3DSA:3.40.50.1820 6 262 5.4E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS28950 1e9935867069d11c92ffa4f99467f254 137 SUPERFAMILY SSF54197 1 110 2.47E-30 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS28950 1e9935867069d11c92ffa4f99467f254 137 PRINTS PR00332 Histidine triad family signature 90 100 1.7E-6 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS28950 1e9935867069d11c92ffa4f99467f254 137 PRINTS PR00332 Histidine triad family signature 4 20 1.7E-6 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS28950 1e9935867069d11c92ffa4f99467f254 137 PRINTS PR00332 Histidine triad family signature 25 43 1.7E-6 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS28950 1e9935867069d11c92ffa4f99467f254 137 Pfam PF01230 HIT domain 14 104 5.7E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein A616_RS28950 1e9935867069d11c92ffa4f99467f254 137 Gene3D G3DSA:3.30.428.10 1 136 1.2E-24 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 A616_RS29015 f81b413378767c19b49c782a39832c69 345 Pfam PF01032 FecCD transport family 33 341 5.0E-90 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS29015 f81b413378767c19b49c782a39832c69 345 Gene3D G3DSA:1.10.3470.10 17 345 2.7E-68 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS29015 f81b413378767c19b49c782a39832c69 345 SUPERFAMILY SSF81345 15 341 2.22E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS29825 5eb97bafbc4967031ca641f027d647e0 247 Gene3D G3DSA:3.30.2030.10 33 170 3.2E-7 T 29-03-2018 A616_RS29825 5eb97bafbc4967031ca641f027d647e0 247 Gene3D G3DSA:3.30.360.40 178 247 1.0E-25 T 29-03-2018 A616_RS29825 5eb97bafbc4967031ca641f027d647e0 247 SUPERFAMILY SSF143842 66 244 9.94E-28 T 29-03-2018 IPR014794 TATA-box binding A616_RS29825 5eb97bafbc4967031ca641f027d647e0 247 Pfam PF08680 TATA-box binding 61 247 1.5E-35 T 29-03-2018 IPR014794 TATA-box binding A616_RS02010 a54834404d118b1b239a3b540a6ddd97 321 SUPERFAMILY SSF46785 1 60 6.85E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02010 a54834404d118b1b239a3b540a6ddd97 321 Pfam PF13280 WYL domain 139 313 7.4E-29 T 29-03-2018 IPR026881 WYL domain A616_RS02010 a54834404d118b1b239a3b540a6ddd97 321 Gene3D G3DSA:1.10.10.10 1 64 3.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02010 a54834404d118b1b239a3b540a6ddd97 321 Pfam PF08279 HTH domain 9 60 9.5E-13 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 A616_RS12075 2de53dc17865649302910d490daa1ff5 306 Gene3D G3DSA:3.20.20.100 1 304 7.1E-76 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS12075 2de53dc17865649302910d490daa1ff5 306 SUPERFAMILY SSF51430 1 295 2.1E-77 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS12075 2de53dc17865649302910d490daa1ff5 306 Pfam PF00248 Aldo/keto reductase family 16 298 6.1E-56 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain A616_RS04345 85d7b348b25ffda93d72d43acc595206 192 Gene3D G3DSA:3.40.630.30 8 191 1.0E-20 T 29-03-2018 A616_RS04345 85d7b348b25ffda93d72d43acc595206 192 Pfam PF13302 Acetyltransferase (GNAT) domain 17 157 1.3E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS04345 85d7b348b25ffda93d72d43acc595206 192 SUPERFAMILY SSF55729 9 183 6.89E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS26305 4d893d77b12b3ebf4c4f164ba123c4d4 196 Gene3D G3DSA:2.40.50.120 48 140 2.1E-16 T 29-03-2018 A616_RS26305 4d893d77b12b3ebf4c4f164ba123c4d4 196 SUPERFAMILY SSF50242 32 139 5.23E-9 T 29-03-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold A616_RS04215 b4e5c5bea4fba8a5d2d6e02f6beddecb 168 Gene3D G3DSA:3.40.1580.10 24 165 3.7E-12 T 29-03-2018 A616_RS04215 b4e5c5bea4fba8a5d2d6e02f6beddecb 168 SUPERFAMILY SSF160631 42 162 8.24E-12 T 29-03-2018 A616_RS28155 a6ba6160fdf79fa9ced39d640fd9427e 109 Pfam PF09858 Predicted membrane protein (DUF2085) 10 94 6.3E-29 T 29-03-2018 IPR019206 Protein of unknown function DUF2085, transmembrane A616_RS19525 dd815697bbd3b52009da931f003b6d1f 429 Pfam PF14395 Phage phiEco32-like COOH.NH2 ligase-type 2 176 428 1.3E-100 T 29-03-2018 IPR025681 Phage phiEco32-like COOH-NH2 ligase-type 2 A616_RS15590 151897e191759dcc6dcb81b2c0cbab4a 491 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 13 460 7.4E-124 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 A616_RS15590 151897e191759dcc6dcb81b2c0cbab4a 491 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 10 477 46.058 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 A616_RS22335 75eac99ca3745b9160848de183a318ee 334 Gene3D G3DSA:3.40.50.2300 162 300 1.6E-21 T 29-03-2018 A616_RS22335 75eac99ca3745b9160848de183a318ee 334 Pfam PF04392 ABC transporter substrate binding protein 42 332 6.2E-101 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein A616_RS22335 75eac99ca3745b9160848de183a318ee 334 Gene3D G3DSA:3.40.50.2300 39 161 3.4E-19 T 29-03-2018 A616_RS22335 75eac99ca3745b9160848de183a318ee 334 SUPERFAMILY SSF53822 53 259 1.89E-15 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS11365 bd2bf1a0415d9bbd8802a368b934c6bb 347 Gene3D G3DSA:3.20.20.140 1 347 1.6E-97 T 29-03-2018 A616_RS11365 bd2bf1a0415d9bbd8802a368b934c6bb 347 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 13 344 1.9E-92 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A616_RS11365 bd2bf1a0415d9bbd8802a368b934c6bb 347 ProSitePatterns PS00869 Renal dipeptidase active site. 118 140 - T 29-03-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A616_RS11365 bd2bf1a0415d9bbd8802a368b934c6bb 347 SUPERFAMILY SSF51556 5 346 2.31E-82 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS14415 6cd98435fe6aec2af95e8c0c9d9c4800 286 Gene3D G3DSA:1.10.3470.10 1 277 3.7E-43 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS14415 6cd98435fe6aec2af95e8c0c9d9c4800 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 5.8E-37 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS06610 f4aa3c0cb09997f99a3f56157927b6e5 108 Pfam PF03551 Transcriptional regulator PadR-like family 14 87 4.8E-24 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS06610 f4aa3c0cb09997f99a3f56157927b6e5 108 SUPERFAMILY SSF46785 10 100 3.22E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06610 f4aa3c0cb09997f99a3f56157927b6e5 108 Gene3D G3DSA:1.10.10.10 1 98 2.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS13425 4837c24eb09dcb6e3b8a6927ade1c8d9 161 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 37 152 2.4E-39 T 29-03-2018 IPR005562 SpoVA A616_RS13425 4837c24eb09dcb6e3b8a6927ade1c8d9 161 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 19 157 1.2E-59 T 29-03-2018 IPR014203 Sporulation stage V, protein AC A616_RS11785 7e0592aaeee64233a1cf2fe0306b0ebf 412 Gene3D G3DSA:3.90.550.10 35 296 8.5E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS11785 7e0592aaeee64233a1cf2fe0306b0ebf 412 Pfam PF13641 Glycosyltransferase like family 2 46 272 1.2E-30 T 29-03-2018 A616_RS11785 7e0592aaeee64233a1cf2fe0306b0ebf 412 SUPERFAMILY SSF53448 47 372 2.91E-38 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS15710 97d62f5dfbb5d03bcc1f358a37fcf94b 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 355 8.8E-67 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A616_RS15710 97d62f5dfbb5d03bcc1f358a37fcf94b 370 Gene3D G3DSA:3.20.20.70 1 369 3.8E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS15710 97d62f5dfbb5d03bcc1f358a37fcf94b 370 SUPERFAMILY SSF51395 5 358 2.29E-98 T 29-03-2018 A616_RS24760 66e1a0fd2af6e16574e6b1980e37d022 316 SUPERFAMILY SSF54593 5 282 7.02E-48 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24760 66e1a0fd2af6e16574e6b1980e37d022 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 8.0E-31 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS24760 66e1a0fd2af6e16574e6b1980e37d022 316 Gene3D G3DSA:3.10.180.10 2 145 1.1E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24760 66e1a0fd2af6e16574e6b1980e37d022 316 Gene3D G3DSA:3.10.180.10 146 311 2.1E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS13900 0f40726e349c638222eda22e1aec3158 199 Pfam PF07187 Protein of unknown function (DUF1405) 28 186 6.7E-56 T 29-03-2018 IPR009845 Protein of unknown function DUF1405 A616_RS26070 5356b135b82b2e2cb256f8953ef97bae 281 SUPERFAMILY SSF53697 99 277 5.13E-39 T 29-03-2018 A616_RS26070 5356b135b82b2e2cb256f8953ef97bae 281 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 77 2.6E-21 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A616_RS26070 5356b135b82b2e2cb256f8953ef97bae 281 SUPERFAMILY SSF46689 5 78 4.3E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS26070 5356b135b82b2e2cb256f8953ef97bae 281 Gene3D G3DSA:1.10.10.10 2 78 3.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS26070 5356b135b82b2e2cb256f8953ef97bae 281 Gene3D G3DSA:3.40.50.10490 79 276 8.9E-34 T 29-03-2018 A616_RS26070 5356b135b82b2e2cb256f8953ef97bae 281 Pfam PF01380 SIS domain 127 254 3.0E-20 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A616_RS20540 148a62c1d058f7aba472024ff0c3e90f 345 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 203 307 3.3E-7 T 29-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain A616_RS05330 af2981983f4836a4aa09b41235a281ee 91 Gene3D G3DSA:1.20.5.320 47 70 6.8E-6 T 29-03-2018 A616_RS05330 af2981983f4836a4aa09b41235a281ee 91 Gene3D G3DSA:1.10.287.540 11 46 6.5E-7 T 29-03-2018 A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 Pfam PF01047 MarR family 40 90 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 Gene3D G3DSA:1.10.10.10 9 150 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 SUPERFAMILY SSF46785 9 144 9.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.1E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS19475 52afc4503b651c3eb54a3c0b4b609ceb 154 SMART SM00347 26 126 2.5E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS14760 e75502d37427a42e6c06caf406d4cb42 313 Pfam PF07859 alpha/beta hydrolase fold 79 287 6.8E-71 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 A616_RS14760 e75502d37427a42e6c06caf406d4cb42 313 SUPERFAMILY SSF53474 56 311 9.14E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS14760 e75502d37427a42e6c06caf406d4cb42 313 Gene3D G3DSA:3.40.50.1820 1 313 2.1E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS13065 68f2fc64c633bd5be07e4b419a14565e 129 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 127 5.4E-37 T 29-03-2018 IPR014211 Stage III sporulation protein AD A616_RS13065 68f2fc64c633bd5be07e4b419a14565e 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 71 126 1.1E-19 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family A616_RS13065 68f2fc64c633bd5be07e4b419a14565e 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 3 57 8.4E-13 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family A616_RS10470 f3190471672c947d6533cc835ea9692d 144 Pfam PF01478 Type IV leader peptidase family 6 109 8.1E-14 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A616_RS24835 76d75c00889b9e848d830592700efd0f 552 SUPERFAMILY SSF53850 53 522 4.95E-71 T 29-03-2018 A616_RS24835 76d75c00889b9e848d830592700efd0f 552 SUPERFAMILY SSF53850 8 15 4.95E-71 T 29-03-2018 A616_RS24835 76d75c00889b9e848d830592700efd0f 552 Gene3D G3DSA:3.40.190.10 47 229 7.4E-26 T 29-03-2018 A616_RS24835 76d75c00889b9e848d830592700efd0f 552 Gene3D G3DSA:3.40.190.10 234 442 2.5E-4 T 29-03-2018 A616_RS24835 76d75c00889b9e848d830592700efd0f 552 Pfam PF13416 Bacterial extracellular solute-binding protein 75 397 5.6E-35 T 29-03-2018 A616_RS23840 714302253cf0d13886a69965e9559a83 171 Pfam PF12952 Domain of unknown function (DUF3841) 4 117 3.7E-20 T 29-03-2018 IPR024211 Protein of unknown function DUF3841 A616_RS20745 9f179e0c5de09e292e1cc885c8b9bf06 154 Pfam PF14343 PrcB C-terminal 80 132 1.5E-12 T 29-03-2018 IPR025748 PrcB C-terminal domain A616_RS29790 bd4cbb44167b7c3cb3b114394e1c7e8a 277 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 194 274 2.1E-17 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A616_RS29790 bd4cbb44167b7c3cb3b114394e1c7e8a 277 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 149 3.6E-28 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A616_RS29790 bd4cbb44167b7c3cb3b114394e1c7e8a 277 Pfam PF00460 Flagella basal body rod protein 4 34 9.6E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A616_RS29790 bd4cbb44167b7c3cb3b114394e1c7e8a 277 SUPERFAMILY SSF117143 91 236 3.01E-16 T 29-03-2018 A616_RS31660 a233ad0c4b0a566fb0668d93902c4c2c 307 SMART SM00849 10 213 5.2E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS31660 a233ad0c4b0a566fb0668d93902c4c2c 307 Pfam PF00753 Metallo-beta-lactamase superfamily 31 201 2.1E-6 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS31660 a233ad0c4b0a566fb0668d93902c4c2c 307 SUPERFAMILY SSF56281 6 259 4.2E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS31660 a233ad0c4b0a566fb0668d93902c4c2c 307 Gene3D G3DSA:3.60.15.10 1 267 2.8E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase A616_RS20465 484faf56f1db9c9bdf6908ce937af5e8 60 Pfam PF13217 Protein of unknown function (DUF4025) 27 56 1.4E-6 T 29-03-2018 IPR025100 Protein of unknown function DUF4025 A616_RS17800 b4ef6c7080353d097b73bf7a1b1abe35 452 Pfam PF01610 Transposase 159 390 5.8E-63 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain A616_RS17800 b4ef6c7080353d097b73bf7a1b1abe35 452 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 87 1.3E-13 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger A616_RS17800 b4ef6c7080353d097b73bf7a1b1abe35 452 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 99 143 7.3E-8 T 29-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 Gene3D G3DSA:3.40.50.2300 27 206 4.6E-34 T 29-03-2018 A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 Pfam PF13458 Periplasmic binding protein 43 390 3.5E-64 T 29-03-2018 IPR028081 Leucine-binding protein domain A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 Gene3D G3DSA:3.40.50.2300 207 378 2.5E-24 T 29-03-2018 A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 85 103 1.6E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 66 82 1.6E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 44 60 1.6E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 271 289 1.6E-8 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 A616_RS27450 eac4e5cb6aa47ece7cd033da1a8a438d 395 SUPERFAMILY SSF53822 42 394 1.44E-84 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS10750 8a258c8719050d4198ac38299bf440d8 164 Pfam PF05163 DinB family 2 150 1.9E-26 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB A616_RS10750 8a258c8719050d4198ac38299bf440d8 164 SUPERFAMILY SSF109854 1 139 8.06E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS10750 8a258c8719050d4198ac38299bf440d8 164 Gene3D G3DSA:1.20.120.450 1 157 1.4E-24 T 29-03-2018 A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 SUPERFAMILY SSF51338 330 351 9.15E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 SUPERFAMILY SSF51338 3 65 9.15E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 Pfam PF01979 Amidohydrolase family 61 346 3.8E-8 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 SUPERFAMILY SSF51556 65 326 1.86E-57 T 29-03-2018 IPR032466 Metal-dependent hydrolase A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 Gene3D G3DSA:2.30.40.10 1 81 2.0E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 PIRSF PIRSF039004 1 381 2.9E-129 T 29-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative A616_RS18355 3194d1c28e6986db8f0f8520b17c6957 381 Gene3D G3DSA:3.20.20.140 82 328 8.7E-40 T 29-03-2018 A616_RS29270 d261c729d6a21fbfdca31781a94196f7 310 Pfam PF03963 Flagellar hook capping protein - N-terminal region 24 78 2.0E-15 T 29-03-2018 IPR005648 Flagellar hook capping protein A616_RS14885 fe246b0bb4daadd6d0f8c02d77fa2a43 398 Pfam PF07690 Major Facilitator Superfamily 10 351 1.1E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS14885 fe246b0bb4daadd6d0f8c02d77fa2a43 398 Gene3D G3DSA:1.20.1250.20 2 194 4.0E-18 T 29-03-2018 A616_RS14885 fe246b0bb4daadd6d0f8c02d77fa2a43 398 SUPERFAMILY SSF103473 4 379 3.4E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS14885 fe246b0bb4daadd6d0f8c02d77fa2a43 398 Gene3D G3DSA:1.20.1250.20 195 382 2.9E-18 T 29-03-2018 A616_RS00320 df5713db28ec75c245034abb3ef09f8a 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 7.9E-60 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A616_RS00320 df5713db28ec75c245034abb3ef09f8a 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.3E-21 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A616_RS19715 99b745c9a6b23649fff22d4b2a3fb024 274 PRINTS PR00127 Clp protease catalytic subunit P signature 146 163 7.4E-6 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS19715 99b745c9a6b23649fff22d4b2a3fb024 274 PRINTS PR00127 Clp protease catalytic subunit P signature 115 135 7.4E-6 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS19715 99b745c9a6b23649fff22d4b2a3fb024 274 PRINTS PR00127 Clp protease catalytic subunit P signature 228 247 7.4E-6 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A616_RS19715 99b745c9a6b23649fff22d4b2a3fb024 274 Gene3D G3DSA:3.90.226.10 64 268 1.6E-25 T 29-03-2018 A616_RS19715 99b745c9a6b23649fff22d4b2a3fb024 274 SUPERFAMILY SSF52096 65 258 1.04E-38 T 29-03-2018 IPR029045 ClpP/crotonase-like domain A616_RS19715 99b745c9a6b23649fff22d4b2a3fb024 274 Pfam PF00574 Clp protease 75 250 8.5E-38 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A616_RS10545 4e7ecdae68e23f57971bdbf2334d445c 183 Pfam PF13523 Acetyltransferase (GNAT) domain 15 156 4.8E-26 T 29-03-2018 A616_RS10545 4e7ecdae68e23f57971bdbf2334d445c 183 Gene3D G3DSA:3.40.630.30 1 180 3.0E-29 T 29-03-2018 A616_RS10545 4e7ecdae68e23f57971bdbf2334d445c 183 SUPERFAMILY SSF55729 5 174 1.54E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS04065 035692fbd0641a72a1ef98dac0e410e8 300 SUPERFAMILY SSF103481 41 141 5.89E-17 T 29-03-2018 A616_RS04065 035692fbd0641a72a1ef98dac0e410e8 300 Pfam PF00892 EamA-like transporter family 151 284 3.2E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS04065 035692fbd0641a72a1ef98dac0e410e8 300 Pfam PF00892 EamA-like transporter family 7 140 3.4E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS04065 035692fbd0641a72a1ef98dac0e410e8 300 SUPERFAMILY SSF103481 188 288 1.24E-12 T 29-03-2018 A616_RS25845 8da63bbc40653caab8a165768f7cb3c0 295 SUPERFAMILY SSF103481 39 136 2.35E-15 T 29-03-2018 A616_RS25845 8da63bbc40653caab8a165768f7cb3c0 295 Pfam PF00892 EamA-like transporter family 145 278 2.5E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS25845 8da63bbc40653caab8a165768f7cb3c0 295 Pfam PF00892 EamA-like transporter family 8 136 1.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS25845 8da63bbc40653caab8a165768f7cb3c0 295 SUPERFAMILY SSF103481 178 280 1.11E-14 T 29-03-2018 A616_RS19155 9d32da0f0e0730949464472f2e742b5b 160 Gene3D G3DSA:3.40.630.30 2 156 1.3E-14 T 29-03-2018 A616_RS19155 9d32da0f0e0730949464472f2e742b5b 160 SUPERFAMILY SSF55729 3 148 3.36E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS19155 9d32da0f0e0730949464472f2e742b5b 160 Pfam PF00583 Acetyltransferase (GNAT) family 26 133 8.8E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS13405 1e87527038a37eb5f87face5b1ceed5a 149 Gene3D G3DSA:3.30.565.10 4 146 1.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13405 1e87527038a37eb5f87face5b1ceed5a 149 SMART SM00387 38 143 4.0E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13405 1e87527038a37eb5f87face5b1ceed5a 149 SUPERFAMILY SSF55874 31 138 1.83E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS13405 1e87527038a37eb5f87face5b1ceed5a 149 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 4 143 36.782 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A616_RS13405 1e87527038a37eb5f87face5b1ceed5a 149 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 6 140 2.7E-63 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A616_RS13405 1e87527038a37eb5f87face5b1ceed5a 149 Pfam PF13581 Histidine kinase-like ATPase domain 13 139 9.2E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A616_RS09545 0af5e49de25dff35ec5ef285db58ebad 386 Pfam PF03845 Spore germination protein 12 343 4.6E-61 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS09545 0af5e49de25dff35ec5ef285db58ebad 386 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 12 374 3.9E-66 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS06435 c15a0dc29ae7e75a75aff1fad112d9c3 271 Pfam PF04865 Baseplate J-like protein 96 232 5.7E-21 T 29-03-2018 IPR006949 Baseplate protein J-like A616_RS24390 ce3232d419da46fc622fb5501e5747c7 379 Gene3D G3DSA:1.20.1250.20 191 378 1.7E-20 T 29-03-2018 A616_RS24390 ce3232d419da46fc622fb5501e5747c7 379 SUPERFAMILY SSF103473 4 372 7.59E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS24390 ce3232d419da46fc622fb5501e5747c7 379 Gene3D G3DSA:1.20.1250.20 3 190 2.9E-25 T 29-03-2018 A616_RS24390 ce3232d419da46fc622fb5501e5747c7 379 Pfam PF07690 Major Facilitator Superfamily 9 321 2.8E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS24500 24a216acff9e5782bcaa7dbf467dc96d 155 Gene3D G3DSA:3.30.500.20 6 129 1.9E-32 T 29-03-2018 A616_RS02305 7e586f2219551c0319b9a74cb58550a6 443 Pfam PF13786 Domain of unknown function (DUF4179) 1 97 2.7E-11 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS02305 7e586f2219551c0319b9a74cb58550a6 443 Gene3D G3DSA:2.60.40.1630 40 196 1.6E-19 T 29-03-2018 A616_RS02305 7e586f2219551c0319b9a74cb58550a6 443 Gene3D G3DSA:2.60.40.1640 201 320 2.9E-7 T 29-03-2018 A616_RS02305 7e586f2219551c0319b9a74cb58550a6 443 Gene3D G3DSA:2.60.40.1640 321 438 1.6E-6 T 29-03-2018 A616_RS23150 42849bc188d132acaa5bb784949b58a2 530 Gene3D G3DSA:3.40.720.10 25 528 1.2E-29 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS23150 42849bc188d132acaa5bb784949b58a2 530 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 50 384 1.5E-15 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A616_RS23150 42849bc188d132acaa5bb784949b58a2 530 SUPERFAMILY SSF53649 453 522 1.53E-42 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS23150 42849bc188d132acaa5bb784949b58a2 530 SUPERFAMILY SSF53649 41 396 1.53E-42 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A616_RS17445 9ef8591fe3f0c4039f4144bf135acbe3 440 Gene3D G3DSA:2.60.120.430 49 213 1.6E-7 T 29-03-2018 A616_RS01065 c76c7de1bfdc204d2b95e35321303e28 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 304 1.1E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS01065 c76c7de1bfdc204d2b95e35321303e28 305 SUPERFAMILY SSF161098 97 287 6.15E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS01065 c76c7de1bfdc204d2b95e35321303e28 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 79 5.4E-14 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS01065 c76c7de1bfdc204d2b95e35321303e28 305 Gene3D G3DSA:1.10.3720.10 29 293 3.3E-46 T 29-03-2018 A616_RS13525 4c66fde72957cdbd076f2018179adec7 376 Gene3D G3DSA:3.40.50.1000 1 365 4.5E-27 T 29-03-2018 IPR023214 HAD-like domain A616_RS13525 4c66fde72957cdbd076f2018179adec7 376 Pfam PF13242 HAD-hyrolase-like 286 371 1.1E-11 T 29-03-2018 A616_RS13525 4c66fde72957cdbd076f2018179adec7 376 SUPERFAMILY SSF56784 2 376 1.25E-39 T 29-03-2018 IPR023214 HAD-like domain A616_RS07010 37eb1dd3da652c818a4b236ea2f4b90a 355 Pfam PF05145 Transition state regulatory protein AbrB 28 340 1.9E-80 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 A616_RS07010 37eb1dd3da652c818a4b236ea2f4b90a 355 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 182 338 6.7E-34 T 29-03-2018 IPR017516 AbrB duplication A616_RS07010 37eb1dd3da652c818a4b236ea2f4b90a 355 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 6 160 8.2E-38 T 29-03-2018 IPR017516 AbrB duplication A616_RS07010 37eb1dd3da652c818a4b236ea2f4b90a 355 PIRSF PIRSF038991 1 348 3.3E-79 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 A616_RS29830 4afd2251b941879bfc8dcba323004b10 76 Pfam PF06612 Protein of unknown function (DUF1146) 16 62 4.2E-22 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 A616_RS29830 4afd2251b941879bfc8dcba323004b10 76 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 70 7.8E-18 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 A616_RS03705 92f73e48414ad636a90bff9df69854fe 117 Gene3D G3DSA:1.20.5.170 27 115 3.1E-5 T 29-03-2018 A616_RS00575 0008edd1ad15d8e38512158a274b2a51 148 Gene3D G3DSA:1.20.120.490 30 147 3.1E-37 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain A616_RS00575 0008edd1ad15d8e38512158a274b2a51 148 SUPERFAMILY SSF158397 29 147 8.5E-35 T 29-03-2018 A616_RS00575 0008edd1ad15d8e38512158a274b2a51 148 Pfam PF03885 Protein of unknown function (DUF327) 15 147 1.8E-40 T 29-03-2018 IPR005585 Protein of unknown function DUF327 A616_RS18160 14787d380bedb44d28bc253d8e508ded 215 Pfam PF13353 4Fe-4S single cluster domain 43 163 3.0E-24 T 29-03-2018 A616_RS18160 14787d380bedb44d28bc253d8e508ded 215 Pfam PF04055 Radical SAM superfamily 52 143 5.3E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A616_RS18160 14787d380bedb44d28bc253d8e508ded 215 Gene3D G3DSA:3.20.20.70 29 163 6.5E-11 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS18160 14787d380bedb44d28bc253d8e508ded 215 SUPERFAMILY SSF102114 54 134 5.1E-8 T 29-03-2018 A616_RS31190 43ca0ec46918bd70d28ed930ca0f32e1 313 Pfam PF01032 FecCD transport family 11 309 1.0E-54 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS31190 43ca0ec46918bd70d28ed930ca0f32e1 313 Gene3D G3DSA:1.10.3470.10 1 313 4.3E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS31190 43ca0ec46918bd70d28ed930ca0f32e1 313 SUPERFAMILY SSF81345 10 309 1.96E-58 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS03855 1d80a6e43b6576bc7187fa9fc7c0182e 400 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 389 1.1E-96 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS03855 1d80a6e43b6576bc7187fa9fc7c0182e 400 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 225 387 2.5E-39 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS18595 2627696ce7f2cbe87e70f0a99b1602d0 236 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 215 5.6E-56 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A616_RS02195 6eff525f100e4b8e3e801d0cb440d0e5 208 Pfam PF02525 Flavodoxin-like fold 3 203 2.2E-40 T 29-03-2018 IPR003680 Flavodoxin-like fold A616_RS02195 6eff525f100e4b8e3e801d0cb440d0e5 208 Gene3D G3DSA:3.40.50.360 2 208 2.2E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS02195 6eff525f100e4b8e3e801d0cb440d0e5 208 SUPERFAMILY SSF52218 1 208 2.74E-47 T 29-03-2018 IPR029039 Flavoprotein-like domain A616_RS02195 6eff525f100e4b8e3e801d0cb440d0e5 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 29.514 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 A616_RS20855 bf12ce68304ea212bf38197275667ff6 116 Pfam PF09685 Domain of unknown function (DUF4870) 9 115 1.2E-38 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 205 412 1.3E-39 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 SUPERFAMILY SSF111369 58 128 1.7E-5 T 29-03-2018 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 Gene3D G3DSA:2.40.50.100 225 377 0.015 T 29-03-2018 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 Gene3D G3DSA:2.40.50.100 68 151 2.5E-9 T 29-03-2018 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 SUPERFAMILY SSF111369 205 336 1.83E-6 T 29-03-2018 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 Gene3D G3DSA:1.10.287.470 152 193 3.7E-5 T 29-03-2018 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 Pfam PF13533 Biotin-lipoyl like 76 117 4.7E-8 T 29-03-2018 A616_RS27265 36815928766adb4b5228e3683a5c1518 415 Pfam PF13437 HlyD family secretion protein 231 324 3.5E-12 T 29-03-2018 A616_RS23155 def30c9119c12b2cb3b89b07f3f77d5b 268 Pfam PF10978 Protein of unknown function (DUF2785) 75 244 1.5E-50 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 A616_RS19400 65eebb1cfab7ee5810bc32834f092e0c 86 Gene3D G3DSA:3.40.50.150 1 66 2.6E-18 T 29-03-2018 A616_RS19400 65eebb1cfab7ee5810bc32834f092e0c 86 Pfam PF01555 DNA methylase 16 65 3.8E-16 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 A616_RS19400 65eebb1cfab7ee5810bc32834f092e0c 86 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 38 56 1.4E-8 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A616_RS19400 65eebb1cfab7ee5810bc32834f092e0c 86 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 19 36 1.4E-8 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 A616_RS19400 65eebb1cfab7ee5810bc32834f092e0c 86 SUPERFAMILY SSF53335 5 65 1.76E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10115 87fdce7d158853f29190b990be0dba17 323 Gene3D G3DSA:3.40.50.720 1 196 3.2E-28 T 29-03-2018 A616_RS10115 87fdce7d158853f29190b990be0dba17 323 Gene3D G3DSA:3.90.25.10 197 319 5.8E-38 T 29-03-2018 A616_RS10115 87fdce7d158853f29190b990be0dba17 323 SUPERFAMILY SSF51735 1 316 2.07E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS10115 87fdce7d158853f29190b990be0dba17 323 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 308 1.3E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS07390 05f18f264146dd687ddbe39ca48dbd94 259 Pfam PF13673 Acetyltransferase (GNAT) domain 153 250 1.5E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS07390 05f18f264146dd687ddbe39ca48dbd94 259 SUPERFAMILY SSF55729 145 252 1.16E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS07390 05f18f264146dd687ddbe39ca48dbd94 259 Gene3D G3DSA:3.40.630.30 14 242 2.4E-19 T 29-03-2018 A616_RS26750 69e1545aefc2344bc5a3f5819875f46a 135 Pfam PF06114 IrrE N-terminal-like domain 8 103 1.4E-9 T 29-03-2018 IPR010359 IrrE N-terminal-like domain A616_RS10100 a279fd7e99f55e8f13f17651758df6d5 368 Gene3D G3DSA:3.40.50.2000 139 366 1.1E-33 T 29-03-2018 A616_RS10100 a279fd7e99f55e8f13f17651758df6d5 368 Pfam PF00534 Glycosyl transferases group 1 201 343 9.4E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS10100 a279fd7e99f55e8f13f17651758df6d5 368 SUPERFAMILY SSF53756 9 366 4.4E-58 T 29-03-2018 A616_RS13485 c8eaed47513ff68fb6836a93cc7f02a2 196 Pfam PF07670 Nucleoside recognition 43 148 6.4E-10 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A616_RS09780 79bb9591a6168109d607f9478e6c4c11 203 SUPERFAMILY SSF81343 4 202 1.57E-56 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09780 79bb9591a6168109d607f9478e6c4c11 203 Gene3D G3DSA:1.20.1300.10 2 203 3.6E-46 T 29-03-2018 A616_RS09780 79bb9591a6168109d607f9478e6c4c11 203 PIRSF PIRSF000170 1 203 3.9E-90 T 29-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute A616_RS09780 79bb9591a6168109d607f9478e6c4c11 203 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 94 192 1.6E-10 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A616_RS09780 79bb9591a6168109d607f9478e6c4c11 203 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 200 1.5E-46 T 29-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit A616_RS23350 db091f041194b3d462e54c1496364780 192 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 1.6E-31 T 29-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 A616_RS03505 e992b37a89cdade5a58d5a49d2026cd4 292 Gene3D G3DSA:3.30.1380.10 78 210 1.1E-25 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS03505 e992b37a89cdade5a58d5a49d2026cd4 292 SUPERFAMILY SSF55166 92 220 1.41E-28 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A616_RS03505 e992b37a89cdade5a58d5a49d2026cd4 292 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 98 212 2.3E-26 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A616_RS09980 e4816d6895d9d9cd3ce812d8091ba5e5 395 SUPERFAMILY SSF103473 5 378 2.49E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS09980 e4816d6895d9d9cd3ce812d8091ba5e5 395 Pfam PF07690 Major Facilitator Superfamily 8 316 5.8E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS09980 e4816d6895d9d9cd3ce812d8091ba5e5 395 Gene3D G3DSA:1.20.1250.20 189 389 4.8E-21 T 29-03-2018 A616_RS09980 e4816d6895d9d9cd3ce812d8091ba5e5 395 Gene3D G3DSA:1.20.1250.20 2 187 1.5E-28 T 29-03-2018 A616_RS04835 8aa22aee0e40f4357ce47af9800d7117 452 Pfam PF02386 Cation transport protein 40 432 2.4E-62 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A616_RS11345 55c2194ff1449aacef32faa88905cbbc 337 Gene3D G3DSA:1.10.3470.10 1 332 1.1E-73 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS11345 55c2194ff1449aacef32faa88905cbbc 337 SUPERFAMILY SSF81345 3 327 7.72E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS11345 55c2194ff1449aacef32faa88905cbbc 337 Pfam PF01032 FecCD transport family 4 327 3.7E-95 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS31780 c06bca7ae585c8548480d43499fb2c61 433 Gene3D G3DSA:3.40.190.10 49 169 6.9E-20 T 29-03-2018 A616_RS31780 c06bca7ae585c8548480d43499fb2c61 433 Gene3D G3DSA:3.40.190.10 170 430 6.0E-46 T 29-03-2018 A616_RS31780 c06bca7ae585c8548480d43499fb2c61 433 Pfam PF01547 Bacterial extracellular solute-binding protein 64 348 2.2E-43 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 A616_RS31780 c06bca7ae585c8548480d43499fb2c61 433 SUPERFAMILY SSF53850 52 425 4.1E-78 T 29-03-2018 A616_RS21485 4c15ad96afdc6f87434395d31ee610d3 200 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 9 161 3.4E-35 T 29-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ A616_RS21485 4c15ad96afdc6f87434395d31ee610d3 200 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 33 159 6.3E-20 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A616_RS21595 28c6a80d1c4a0c17500f0935a72812af 41 Pfam PF13790 SR1 protein 1 35 2.2E-17 T 29-03-2018 IPR025236 SR1 protein A616_RS27175 a367939ee780e3bb6229263aeca89c98 460 PIRSF PIRSF005690 2 455 8.8E-119 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS27175 a367939ee780e3bb6229263aeca89c98 460 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 6 431 9.3E-126 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 460 639 2.4E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Pfam PF00672 HAMP domain 331 381 2.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Gene3D G3DSA:1.10.287.950 440 693 1.2E-54 T 29-03-2018 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Gene3D G3DSA:3.30.450.20 33 191 2.9E-12 T 29-03-2018 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Pfam PF02743 Cache domain 47 292 6.2E-17 T 29-03-2018 IPR033479 Double Cache domain 1 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 SMART SM00283 414 689 2.3E-70 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 SUPERFAMILY SSF58104 420 688 4.84E-66 T 29-03-2018 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 SUPERFAMILY SSF58104 360 387 4.84E-66 T 29-03-2018 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Gene3D G3DSA:3.30.450.20 192 309 4.7E-12 T 29-03-2018 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 Gene3D G3DSA:1.10.287.950 352 439 8.3E-4 T 29-03-2018 A616_RS24050 c8e2fd054004ecab26b668593c4fdd3c 693 SMART SM00304 330 385 2.3E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A616_RS04005 d06ebdb7f8c499a594242640bca866a8 281 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 279 38.476 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A616_RS04005 d06ebdb7f8c499a594242640bca866a8 281 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 49 278 1.5E-65 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A616_RS04005 d06ebdb7f8c499a594242640bca866a8 281 Pfam PF02666 Phosphatidylserine decarboxylase 59 276 5.8E-59 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A616_RS20955 d36db0e5a4dc3af8ac0cb95345dbc1bc 174 Pfam PF07484 Phage Tail Collar Domain 6 61 4.2E-23 T 29-03-2018 IPR011083 Phage tail collar domain A616_RS20955 d36db0e5a4dc3af8ac0cb95345dbc1bc 174 Gene3D G3DSA:3.90.1340.10 1 65 1.3E-17 T 29-03-2018 IPR011083 Phage tail collar domain A616_RS20955 d36db0e5a4dc3af8ac0cb95345dbc1bc 174 SUPERFAMILY SSF88874 1 167 8.46E-46 T 29-03-2018 A616_RS32170 31e0f814ca21f8a3c924073a23f6e469 302 Pfam PF09991 Predicted membrane protein (DUF2232) 17 287 1.8E-34 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 A616_RS12010 a3bb28b5ca614ea2b4e7fb66b5231185 443 Pfam PF13786 Domain of unknown function (DUF4179) 39 133 1.7E-16 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS12010 a3bb28b5ca614ea2b4e7fb66b5231185 443 Gene3D G3DSA:2.60.40.1630 72 216 2.2E-20 T 29-03-2018 A616_RS12010 a3bb28b5ca614ea2b4e7fb66b5231185 443 Gene3D G3DSA:2.60.40.1640 222 342 7.3E-9 T 29-03-2018 A616_RS21900 d56997c251990a8d483cf20d5ca47120 305 Gene3D G3DSA:3.90.1200.10 113 302 2.1E-18 T 29-03-2018 A616_RS21900 d56997c251990a8d483cf20d5ca47120 305 Pfam PF01636 Phosphotransferase enzyme family 37 263 6.7E-30 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase A616_RS21900 d56997c251990a8d483cf20d5ca47120 305 SUPERFAMILY SSF56112 20 266 5.1E-34 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 PIRSF PIRSF005539 1 292 1.5E-102 T 29-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 4 286 1.3E-96 T 29-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 Gene3D G3DSA:3.40.50.1820 1 289 3.0E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 55 66 7.2E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 28 36 7.2E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 98 112 7.2E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 SUPERFAMILY SSF53474 6 288 1.11E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS25895 b01f7d7c4136fdce64426a4fc7cd1a05 292 Pfam PF00561 alpha/beta hydrolase fold 27 274 1.0E-29 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 Pfam PF00664 ABC transporter transmembrane region 17 285 3.7E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 SMART SM00382 360 546 1.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 SUPERFAMILY SSF90123 5 313 4.58E-74 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 Gene3D G3DSA:1.20.1560.10 1 313 2.0E-70 T 29-03-2018 A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 SUPERFAMILY SSF52540 323 570 3.26E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 Gene3D G3DSA:3.40.50.300 316 576 1.1E-69 T 29-03-2018 A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS08620 e8b9050906afa15c0ffab285d5fc7dfa 576 Pfam PF00005 ABC transporter 351 500 8.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS02340 4145cf108755651d419ed1a973e676da 230 Pfam PF02659 Putative manganese efflux pump 136 225 7.8E-13 T 29-03-2018 IPR003810 Putative manganese efflux pump A616_RS02340 4145cf108755651d419ed1a973e676da 230 Pfam PF02659 Putative manganese efflux pump 4 81 2.2E-7 T 29-03-2018 IPR003810 Putative manganese efflux pump A616_RS02340 4145cf108755651d419ed1a973e676da 230 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 6 227 3.0E-56 T 29-03-2018 IPR014205 Sporulation protein YtaF A616_RS26800 009623e4d459736cd8d8c755c03d1a6c 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 121 4.2E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS26800 009623e4d459736cd8d8c755c03d1a6c 130 Gene3D G3DSA:3.10.180.10 2 122 6.4E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS26800 009623e4d459736cd8d8c755c03d1a6c 130 SUPERFAMILY SSF54593 2 125 9.02E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS09135 9cae8358fa95b079f0222e8f94bc0ef2 277 SUPERFAMILY SSF161098 5 277 1.78E-72 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS09135 9cae8358fa95b079f0222e8f94bc0ef2 277 Gene3D G3DSA:1.10.3720.10 1 264 8.5E-47 T 29-03-2018 A616_RS09135 9cae8358fa95b079f0222e8f94bc0ef2 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 270 1.2E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25470 be7f2dcf9dafc8fd8a060f7d9bb3f38e 970 Pfam PF14903 WG containing repeat 236 263 0.014 T 29-03-2018 IPR032774 WG containing repeat A616_RS25470 be7f2dcf9dafc8fd8a060f7d9bb3f38e 970 Pfam PF14903 WG containing repeat 75 107 0.028 T 29-03-2018 IPR032774 WG containing repeat A616_RS20550 ba92463fb61fd38bfd8a1376b985329f 382 Pfam PF13439 Glycosyltransferase Family 4 21 169 8.8E-10 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A616_RS20550 ba92463fb61fd38bfd8a1376b985329f 382 SUPERFAMILY SSF53756 13 379 7.18E-69 T 29-03-2018 A616_RS20550 ba92463fb61fd38bfd8a1376b985329f 382 Pfam PF00534 Glycosyl transferases group 1 187 358 8.0E-32 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 A616_RS20550 ba92463fb61fd38bfd8a1376b985329f 382 Gene3D G3DSA:3.40.50.2000 153 376 3.8E-47 T 29-03-2018 A616_RS17690 4f97bd615d56ba126a7c34a7d9fcd789 62 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS17690 4f97bd615d56ba126a7c34a7d9fcd789 62 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 3.1E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A616_RS17690 4f97bd615d56ba126a7c34a7d9fcd789 62 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS26880 e2b92b85f4c763c5340b1cdda4949475 190 Gene3D G3DSA:3.40.630.30 3 186 5.1E-24 T 29-03-2018 A616_RS26880 e2b92b85f4c763c5340b1cdda4949475 190 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 7.3E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS26880 e2b92b85f4c763c5340b1cdda4949475 190 SUPERFAMILY SSF55729 9 179 2.47E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS07775 b3ed379009f944b55c533f8d318b5b08 450 Pfam PF03553 Na+/H+ antiporter family 157 443 3.5E-48 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A616_RS07775 b3ed379009f944b55c533f8d318b5b08 450 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 11 444 5.9E-135 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A616_RS24135 26e89cc4254375e91f651dff65f28275 332 Gene3D G3DSA:3.20.20.140 1 317 7.9E-27 T 29-03-2018 A616_RS24135 26e89cc4254375e91f651dff65f28275 332 SUPERFAMILY SSF89550 63 85 4.05E-25 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS24135 26e89cc4254375e91f651dff65f28275 332 SUPERFAMILY SSF89550 130 330 4.05E-25 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS20030 e24a833dc28ec5cafc52869e24b0fd3e 272 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 4 267 2.2E-46 T 29-03-2018 IPR022524 Flagellar assembly FliH, Bacilli A616_RS20030 e24a833dc28ec5cafc52869e24b0fd3e 272 Pfam PF02108 Flagellar assembly protein FliH 132 257 1.9E-18 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE A616_RS20030 e24a833dc28ec5cafc52869e24b0fd3e 272 Gene3D G3DSA:1.20.5.620 42 102 2.9E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 Gene3D G3DSA:1.20.1250.20 1 204 9.7E-46 T 29-03-2018 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 PRINTS PR01035 Tetracycline resistance protein signature 22 38 2.8E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 PRINTS PR01035 Tetracycline resistance protein signature 137 159 2.8E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 PRINTS PR01035 Tetracycline resistance protein signature 165 185 2.8E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 PRINTS PR01035 Tetracycline resistance protein signature 277 298 2.8E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 PRINTS PR01035 Tetracycline resistance protein signature 249 269 2.8E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 PRINTS PR01035 Tetracycline resistance protein signature 337 360 2.8E-26 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 Gene3D G3DSA:1.20.1250.20 205 398 2.5E-22 T 29-03-2018 A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 SUPERFAMILY SSF103473 9 389 1.44E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS23775 f27a3a680aec355a43f33bffc0546c44 398 Pfam PF07690 Major Facilitator Superfamily 16 273 1.4E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS13415 9456edb25c1b2673887f82a1055913fb 204 Gene3D G3DSA:2.60.480.10 2 92 5.5E-22 T 29-03-2018 A616_RS13415 9456edb25c1b2673887f82a1055913fb 204 Pfam PF12164 Stage V sporulation protein AA 3 87 2.7E-18 T 29-03-2018 IPR021997 Stage V sporulation protein AA A616_RS08610 f9192e8cddb7f7c992fb287f00d66ca7 138 Gene3D G3DSA:3.10.180.10 8 138 6.9E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS08610 f9192e8cddb7f7c992fb287f00d66ca7 138 SUPERFAMILY SSF54593 9 133 4.97E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS13890 222f5153e97ea1eea53503c23ad3069b 223 SUPERFAMILY SSF81342 5 223 4.08E-64 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A616_RS13890 222f5153e97ea1eea53503c23ad3069b 223 Gene3D G3DSA:1.20.810.10 2 223 1.5E-78 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A616_RS13890 222f5153e97ea1eea53503c23ad3069b 223 Pfam PF00033 Cytochrome b/b6/petB 40 218 1.5E-51 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A616_RS13890 222f5153e97ea1eea53503c23ad3069b 223 PIRSF PIRSF000032 2 223 1.3E-100 T 29-03-2018 IPR023530 Cytochrome b6, PetB GO:0005506|GO:0016021|GO:0020037|GO:0022900|GO:0045158 A616_RS21095 ba450c43a33d7d45be4dcbc17741173e 168 Pfam PF13785 Domain of unknown function (DUF4178) 28 159 4.8E-28 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 A616_RS21230 390510bf4c90d166b3ec509d83a77667 276 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 31 270 2.0E-77 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase A616_RS21230 390510bf4c90d166b3ec509d83a77667 276 Gene3D G3DSA:3.60.140.10 4 276 1.7E-84 T 29-03-2018 A616_RS21230 390510bf4c90d166b3ec509d83a77667 276 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 37 271 1.0E-58 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase A616_RS21230 390510bf4c90d166b3ec509d83a77667 276 SUPERFAMILY SSF64438 20 273 1.79E-78 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A616_RS09530 f22fa2d19661ca860232e742e2d52a4d 127 Pfam PF06961 Protein of unknown function (DUF1294) 44 98 1.2E-18 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 A616_RS20490 0d4c183d033edec891ecb7706cdafa0e 290 SUPERFAMILY SSF51735 2 287 3.61E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS20490 0d4c183d033edec891ecb7706cdafa0e 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 208 9.2E-6 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS20490 0d4c183d033edec891ecb7706cdafa0e 290 Gene3D G3DSA:3.40.50.720 1 290 2.1E-29 T 29-03-2018 A616_RS11980 a5fc47a06e608f0dcbca0b6b85121785 330 Pfam PF09323 Domain of unknown function (DUF1980) 12 231 3.8E-34 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 A616_RS11980 a5fc47a06e608f0dcbca0b6b85121785 330 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 30 319 4.1E-57 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 A616_RS04420 aee06f6569cba1fe8dc83b0a53ea2b2b 177 SUPERFAMILY SSF55729 2 171 7.93E-44 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS04420 aee06f6569cba1fe8dc83b0a53ea2b2b 177 Gene3D G3DSA:3.40.630.30 2 177 3.7E-32 T 29-03-2018 A616_RS04420 aee06f6569cba1fe8dc83b0a53ea2b2b 177 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 5.3E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS20910 5355314a38a1af4ddded0a1312b7f58f 389 SUPERFAMILY SSF56300 72 329 1.5E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS20910 5355314a38a1af4ddded0a1312b7f58f 389 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 73 311 4.9E-77 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS20910 5355314a38a1af4ddded0a1312b7f58f 389 Gene3D G3DSA:3.60.21.10 58 341 1.8E-56 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS20910 5355314a38a1af4ddded0a1312b7f58f 389 SMART SM00854 72 312 3.7E-90 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS29700 03dd1fb1d60415aab6bd1ed3ac6c9c2d 617 Pfam PF00005 ABC transporter 45 176 1.0E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS29700 03dd1fb1d60415aab6bd1ed3ac6c9c2d 617 SMART SM00382 54 236 2.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS29700 03dd1fb1d60415aab6bd1ed3ac6c9c2d 617 Gene3D G3DSA:3.40.50.300 3 288 7.4E-50 T 29-03-2018 A616_RS29700 03dd1fb1d60415aab6bd1ed3ac6c9c2d 617 SUPERFAMILY SSF52540 21 244 2.66E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS29700 03dd1fb1d60415aab6bd1ed3ac6c9c2d 617 Pfam PF14524 Wzt C-terminal domain 461 598 1.7E-14 T 29-03-2018 IPR029439 Wzt, C-terminal A616_RS29700 03dd1fb1d60415aab6bd1ed3ac6c9c2d 617 Gene3D G3DSA:2.70.50.60 453 599 2.1E-18 T 29-03-2018 A616_RS22425 0972cd92557402c41f2933f3770fb571 486 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 100 271 5.6E-38 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS22425 0972cd92557402c41f2933f3770fb571 486 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 100 271 1.6E-44 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS18390 f8b482a2d2aa10750539d711fca51899 108 Pfam PF01527 Transposase 8 62 2.9E-6 T 29-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 A616_RS18390 f8b482a2d2aa10750539d711fca51899 108 SUPERFAMILY SSF46689 8 92 1.45E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS18390 f8b482a2d2aa10750539d711fca51899 108 Gene3D G3DSA:1.10.10.10 2 67 8.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17700 66c1cae5f5ea702ac30e41f5b3119eb1 156 Gene3D G3DSA:1.10.10.10 87 156 3.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31350 ec68cbc9727a829b1c648b0127ecdacb 273 Gene3D G3DSA:3.20.20.150 1 270 4.9E-51 T 29-03-2018 A616_RS31350 ec68cbc9727a829b1c648b0127ecdacb 273 SUPERFAMILY SSF51658 6 259 1.22E-46 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS31350 ec68cbc9727a829b1c648b0127ecdacb 273 Pfam PF01261 Xylose isomerase-like TIM barrel 29 232 1.7E-26 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A616_RS07075 aab8cbbb304c4aa0a0e5f96fc24ac339 105 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 93 6.3E-15 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A616_RS07075 aab8cbbb304c4aa0a0e5f96fc24ac339 105 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 13 101 2.5E-28 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 A616_RS10380 5e970444755ded58a3a465b885076314 109 SUPERFAMILY SSF46785 10 101 5.57E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10380 5e970444755ded58a3a465b885076314 109 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 1.3E-20 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS10380 5e970444755ded58a3a465b885076314 109 Gene3D G3DSA:1.10.10.10 1 91 2.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05355 7b10ee2bc4fcd3d043b28a4d086d0eca 237 Pfam PF12679 ABC-2 family transporter protein 12 236 2.7E-14 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS20810 9cc331077e1251760cc8539478fdd86e 86 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 1.0E-34 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 A616_RS20810 9cc331077e1251760cc8539478fdd86e 86 Hamap MF_01503 UPF0296 protein . 3 86 29.67 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 A616_RS20810 9cc331077e1251760cc8539478fdd86e 86 Pfam PF04025 Domain of unknown function (DUF370) 5 77 2.7E-38 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 A616_RS02525 6e7cc4eae301b8c5af790b78d05b2484 359 Pfam PF04235 Protein of unknown function (DUF418) 191 349 9.2E-33 T 29-03-2018 IPR007349 Domain of unknown function DUF418 A616_RS13875 2a84adca329fede4b2bb8a5ffe583674 71 SMART SM00914 26 62 4.3E-10 T 29-03-2018 IPR014957 IDEAL domain A616_RS13875 2a84adca329fede4b2bb8a5ffe583674 71 Pfam PF08858 IDEAL domain 26 62 1.7E-13 T 29-03-2018 IPR014957 IDEAL domain A616_RS23300 0a76efeb177a061441b77a714f21c2f6 212 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 15 212 1.1E-78 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent A616_RS23300 0a76efeb177a061441b77a714f21c2f6 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 36 130 8.3E-15 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A616_RS23300 0a76efeb177a061441b77a714f21c2f6 212 SUPERFAMILY SSF50475 31 148 3.93E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS23300 0a76efeb177a061441b77a714f21c2f6 212 Gene3D G3DSA:2.30.110.10 27 189 1.5E-26 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS21400 87494400d2fed3a6563cd79cdac7f08d 70 Pfam PF00364 Biotin-requiring enzyme 3 69 4.0E-18 T 29-03-2018 IPR000089 Biotin/lipoyl attachment A616_RS21400 87494400d2fed3a6563cd79cdac7f08d 70 SUPERFAMILY SSF51230 3 70 3.66E-20 T 29-03-2018 IPR011053 Single hybrid motif A616_RS21400 87494400d2fed3a6563cd79cdac7f08d 70 Gene3D G3DSA:2.40.50.100 41 70 1.6E-6 T 29-03-2018 A616_RS21400 87494400d2fed3a6563cd79cdac7f08d 70 Gene3D G3DSA:2.40.50.100 3 40 3.6E-10 T 29-03-2018 A616_RS10335 bf697bffb21e4e9c5f0abe61d95ed317 272 Pfam PF01578 Cytochrome C assembly protein 66 264 8.9E-29 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A616_RS03650 795f547486de65b80b178eb8666759de 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 4.5E-13 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A616_RS03650 795f547486de65b80b178eb8666759de 258 SUPERFAMILY SSF52540 3 252 6.27E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS03650 795f547486de65b80b178eb8666759de 258 Pfam PF00005 ABC transporter 20 179 5.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS03650 795f547486de65b80b178eb8666759de 258 SMART SM00382 28 228 4.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS03650 795f547486de65b80b178eb8666759de 258 Gene3D G3DSA:3.40.50.300 1 257 1.3E-59 T 29-03-2018 A616_RS15925 fb6363d3ff333b7cb08bcd4077074687 361 Gene3D G3DSA:3.40.710.10 6 354 7.1E-76 T 29-03-2018 A616_RS15925 fb6363d3ff333b7cb08bcd4077074687 361 SUPERFAMILY SSF56601 16 336 2.22E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS15925 fb6363d3ff333b7cb08bcd4077074687 361 Pfam PF00144 Beta-lactamase 28 344 1.7E-60 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS28130 4fef7992a5254fcc19c3c76fda69f5d6 112 Gene3D G3DSA:1.10.10.10 37 111 7.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS28130 4fef7992a5254fcc19c3c76fda69f5d6 112 Pfam PF08281 Sigma-70, region 4 53 93 3.0E-7 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS28130 4fef7992a5254fcc19c3c76fda69f5d6 112 SUPERFAMILY SSF88659 44 110 1.87E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A616_RS18600 b2ec3526eba8e5245a51f09ed60f389e 176 Pfam PF12867 DinB superfamily 35 163 1.3E-15 T 29-03-2018 IPR024775 DinB-like domain A616_RS18600 b2ec3526eba8e5245a51f09ed60f389e 176 SUPERFAMILY SSF109854 28 163 3.05E-21 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS18600 b2ec3526eba8e5245a51f09ed60f389e 176 Gene3D G3DSA:1.20.120.450 25 164 2.4E-17 T 29-03-2018 A616_RS27600 ea20c4c901413c0f9890af40ad0d86e7 139 Gene3D G3DSA:1.20.5.1070 7 85 6.6E-4 T 29-03-2018 A616_RS11815 a61e13f6e9a6edbea72d0d3ec696f65c 230 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 20 35 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS11815 a61e13f6e9a6edbea72d0d3ec696f65c 230 SMART SM00882 8 219 9.2E-73 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS11815 a61e13f6e9a6edbea72d0d3ec696f65c 230 SUPERFAMILY SSF100950 6 222 5.98E-78 T 29-03-2018 A616_RS11815 a61e13f6e9a6edbea72d0d3ec696f65c 230 Gene3D G3DSA:3.40.1080.10 2 229 3.9E-79 T 29-03-2018 A616_RS11815 a61e13f6e9a6edbea72d0d3ec696f65c 230 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 9 220 5.7E-67 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 A616_RS11815 a61e13f6e9a6edbea72d0d3ec696f65c 230 Pfam PF01144 Coenzyme A transferase 10 218 1.7E-67 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 A616_RS29235 70ba7cec0f8f52226b53f8ba09e403a8 391 Pfam PF13393 Histidyl-tRNA synthetase 12 320 9.7E-83 T 29-03-2018 A616_RS29235 70ba7cec0f8f52226b53f8ba09e403a8 391 PIRSF PIRSF001549 4 388 2.1E-84 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A616_RS29235 70ba7cec0f8f52226b53f8ba09e403a8 391 Gene3D G3DSA:3.30.930.10 2 324 1.0E-64 T 29-03-2018 A616_RS29235 70ba7cec0f8f52226b53f8ba09e403a8 391 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 374 31.431 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A616_RS29235 70ba7cec0f8f52226b53f8ba09e403a8 391 SUPERFAMILY SSF55681 10 323 1.81E-64 T 29-03-2018 A616_RS29235 70ba7cec0f8f52226b53f8ba09e403a8 391 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 14 324 1.1E-100 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A616_RS04115 965a2c387546adf8e2b8ffdccb2b9541 234 Gene3D G3DSA:1.20.5.50 4 58 0.0027 T 29-03-2018 A616_RS04115 965a2c387546adf8e2b8ffdccb2b9541 234 Gene3D G3DSA:1.20.5.50 59 148 0.033 T 29-03-2018 A616_RS05610 d9ce722b9ddc9e8b20a045c164285764 377 SUPERFAMILY SSF56349 63 364 5.59E-71 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS05610 d9ce722b9ddc9e8b20a045c164285764 377 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 63 117 1.1E-13 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS05610 d9ce722b9ddc9e8b20a045c164285764 377 Pfam PF14657 Arm DNA-binding domain 12 54 7.7E-15 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain A616_RS05610 d9ce722b9ddc9e8b20a045c164285764 377 Gene3D G3DSA:1.10.150.130 57 170 2.4E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS05610 d9ce722b9ddc9e8b20a045c164285764 377 Pfam PF00589 Phage integrase family 174 356 5.2E-27 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS05610 d9ce722b9ddc9e8b20a045c164285764 377 Gene3D G3DSA:1.10.443.10 171 359 2.6E-43 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS09620 86b84e2b508b7695e483e9d701a0c702 253 Gene3D G3DSA:2.60.40.1630 28 244 1.2E-22 T 29-03-2018 A616_RS09620 86b84e2b508b7695e483e9d701a0c702 253 Pfam PF13786 Domain of unknown function (DUF4179) 46 130 1.8E-8 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS09265 1920d30108c77f4ca62357e8c180b036 207 SUPERFAMILY SSF50475 8 186 5.79E-37 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS09265 1920d30108c77f4ca62357e8c180b036 207 Gene3D G3DSA:2.30.110.10 1 202 1.6E-53 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS09265 1920d30108c77f4ca62357e8c180b036 207 Pfam PF04299 Putative FMN-binding domain 2 159 3.3E-46 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type A616_RS09265 1920d30108c77f4ca62357e8c180b036 207 PIRSF PIRSF010372 1 204 3.3E-61 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type A616_RS20825 2abbe70c1feb7afbeb3534590b52cf67 113 Pfam PF10710 Protein of unknown function (DUF2512) 21 107 3.7E-19 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 A616_RS30275 d34b37ecf43c53988f800f75238c10bb 283 Pfam PF02517 CAAX protease self-immunity 132 227 2.7E-12 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A616_RS31385 57db4d79a3bd5025a6634c436408e070 299 Gene3D G3DSA:1.10.3660.10 17 121 0.002 T 29-03-2018 A616_RS31385 57db4d79a3bd5025a6634c436408e070 299 Pfam PF09375 Imelysin 66 293 2.6E-36 T 29-03-2018 IPR018976 Peptidase M75, Imelysin A616_RS28600 cb8d4689ef0ef804cc072503dd0ef020 271 Gene3D G3DSA:2.60.120.40 130 270 1.2E-16 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 A616_RS28600 cb8d4689ef0ef804cc072503dd0ef020 271 Pfam PF01391 Collagen triple helix repeat (20 copies) 40 91 1.8E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat A616_RS28600 cb8d4689ef0ef804cc072503dd0ef020 271 Pfam PF01391 Collagen triple helix repeat (20 copies) 76 131 3.1E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat A616_RS28600 cb8d4689ef0ef804cc072503dd0ef020 271 Gene3D G3DSA:2.160.20.50 26 97 1.6E-8 T 29-03-2018 A616_RS08185 61f680289d87bc906e9f683d133d0281 154 Gene3D G3DSA:3.40.630.30 10 152 8.7E-24 T 29-03-2018 A616_RS08185 61f680289d87bc906e9f683d133d0281 154 SUPERFAMILY SSF55729 12 140 8.58E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS08185 61f680289d87bc906e9f683d133d0281 154 Pfam PF00583 Acetyltransferase (GNAT) family 28 139 1.9E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS31400 f62800831694cf1f8e9ecb20e6f17b4f 309 Pfam PF01040 UbiA prenyltransferase family 45 269 1.1E-22 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A616_RS01885 4f5f0a708e32922ee50265fc8e9fc4a7 99 Pfam PF02805 Metal binding domain of Ada 43 86 6.9E-5 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A616_RS01885 4f5f0a708e32922ee50265fc8e9fc4a7 99 Gene3D G3DSA:3.40.10.10 7 91 5.2E-21 T 29-03-2018 IPR035451 Ada-like domain A616_RS01885 4f5f0a708e32922ee50265fc8e9fc4a7 99 SUPERFAMILY SSF57884 36 95 1.23E-11 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 A616_RS20705 52fa49d39e27c56f979e159c4c27af6c 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.149 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS20705 52fa49d39e27c56f979e159c4c27af6c 62 SUPERFAMILY SSF143800 1 61 1.04E-22 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20705 52fa49d39e27c56f979e159c4c27af6c 62 Pfam PF00830 Ribosomal L28 family 3 57 2.2E-19 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS20705 52fa49d39e27c56f979e159c4c27af6c 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 2.3E-21 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS20705 52fa49d39e27c56f979e159c4c27af6c 62 Gene3D G3DSA:2.30.170.40 2 60 1.9E-18 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS19850 f193de538ad69c921e1bc2a614698c54 261 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 220 246 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 A616_RS19850 f193de538ad69c921e1bc2a614698c54 261 Pfam PF01148 Cytidylyltransferase family 2 258 2.9E-67 T 29-03-2018 A616_RS28090 0daf40f3a7716ff84daf6d9afc33e268 128 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 6 127 1.6E-8 T 29-03-2018 IPR014986 Clostridium phage phiCD119, XkdN A616_RS31280 7ee7e32c53869f4d736902dc2698c228 210 PIRSF PIRSF006324 1 208 6.2E-58 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS31280 7ee7e32c53869f4d736902dc2698c228 210 Pfam PF01810 LysE type translocator 16 205 2.7E-40 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS31800 6925330fd001bb8bf3a50cd378686655 332 Gene3D G3DSA:3.30.420.40 1 119 1.3E-27 T 29-03-2018 A616_RS31800 6925330fd001bb8bf3a50cd378686655 332 SUPERFAMILY SSF53067 1 325 5.76E-66 T 29-03-2018 A616_RS31800 6925330fd001bb8bf3a50cd378686655 332 Gene3D G3DSA:3.30.420.40 120 330 8.0E-59 T 29-03-2018 A616_RS31800 6925330fd001bb8bf3a50cd378686655 332 Pfam PF00480 ROK family 5 321 2.5E-69 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS31800 6925330fd001bb8bf3a50cd378686655 332 ProSitePatterns PS01125 ROK family signature. 134 161 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A616_RS24265 2e78bb6dbd981c9b0d7b92d0c5a799b6 141 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 3 140 42.6 T 29-03-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 A616_RS24265 2e78bb6dbd981c9b0d7b92d0c5a799b6 141 SUPERFAMILY SSF54593 5 131 7.25E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS24265 2e78bb6dbd981c9b0d7b92d0c5a799b6 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 3.2E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS24265 2e78bb6dbd981c9b0d7b92d0c5a799b6 141 Gene3D G3DSA:3.10.180.10 4 137 9.6E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS27920 7713a73f5c48e7f2dae73d339f9de5d7 281 SUPERFAMILY SSF161098 88 272 3.53E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS27920 7713a73f5c48e7f2dae73d339f9de5d7 281 Gene3D G3DSA:1.10.3720.10 43 280 8.3E-34 T 29-03-2018 A616_RS27920 7713a73f5c48e7f2dae73d339f9de5d7 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 269 1.6E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS06405 9e2fb73d86ed6f67061156b424b565ee 129 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 49 128 4.4E-9 T 29-03-2018 IPR014986 Clostridium phage phiCD119, XkdN A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 SMART SM00116 81 128 2.3E-12 T 29-03-2018 IPR000644 CBS domain A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 SMART SM00116 16 64 2.2E-6 T 29-03-2018 IPR000644 CBS domain A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 SUPERFAMILY SSF54631 4 123 5.05E-33 T 29-03-2018 A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 Pfam PF00571 CBS domain 75 124 5.5E-11 T 29-03-2018 IPR000644 CBS domain A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 Pfam PF00571 CBS domain 10 60 2.5E-11 T 29-03-2018 IPR000644 CBS domain A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 Gene3D G3DSA:3.10.580.10 1 69 3.6E-14 T 29-03-2018 A616_RS12725 064d13401906ece4f4e0487b7e1700c2 146 Gene3D G3DSA:3.10.580.10 70 145 1.3E-13 T 29-03-2018 A616_RS22745 d2d5b78b2ad39ec9c948915eb4e3da39 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 60 255 9.2E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS22745 d2d5b78b2ad39ec9c948915eb4e3da39 258 Pfam PF10370 Domain of unknown function (DUF2437) 2 55 1.5E-6 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 A616_RS22745 d2d5b78b2ad39ec9c948915eb4e3da39 258 Gene3D G3DSA:3.90.850.10 29 258 2.8E-89 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS22745 d2d5b78b2ad39ec9c948915eb4e3da39 258 SUPERFAMILY SSF56529 54 257 7.59E-81 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A616_RS19760 d24faedf5157edb58117143a1588c5fe 325 SUPERFAMILY SSF88713 114 317 1.27E-51 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS19760 d24faedf5157edb58117143a1588c5fe 325 Gene3D G3DSA:3.20.20.370 110 322 1.3E-47 T 29-03-2018 A616_RS19760 d24faedf5157edb58117143a1588c5fe 325 Pfam PF01522 Polysaccharide deacetylase 131 245 6.9E-28 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS27895 4ed73e8eebcdcdce0be694902c10cc0c 203 Pfam PF09335 SNARE associated Golgi protein 34 160 4.4E-17 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS19915 2ea5b23c610641353c59a5b7964697fb 208 SUPERFAMILY SSF103039 6 202 1.06E-53 T 29-03-2018 IPR028976 CheC-like domain A616_RS19915 2ea5b23c610641353c59a5b7964697fb 208 Pfam PF04509 CheC-like family 13 47 8.0E-13 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 A616_RS19915 2ea5b23c610641353c59a5b7964697fb 208 Pfam PF04509 CheC-like family 109 143 1.2E-10 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 A616_RS19915 2ea5b23c610641353c59a5b7964697fb 208 Gene3D G3DSA:3.40.1550.10 4 205 5.9E-56 T 29-03-2018 IPR028976 CheC-like domain A616_RS14430 e1caf2e900f288d79fd3a31898cee7d0 271 Gene3D G3DSA:1.10.3810.10 59 260 4.0E-71 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS14430 e1caf2e900f288d79fd3a31898cee7d0 271 Pfam PF00912 Transglycosylase 66 241 2.8E-62 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 A616_RS14430 e1caf2e900f288d79fd3a31898cee7d0 271 SUPERFAMILY SSF53955 69 265 3.09E-69 T 29-03-2018 IPR023346 Lysozyme-like domain A616_RS16905 28cc1459fc326dd3abbcf72c824e619f 397 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 257 341 1.1E-17 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal A616_RS16905 28cc1459fc326dd3abbcf72c824e619f 397 Pfam PF01385 Probable transposase 170 289 1.1E-13 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A616_RS16905 28cc1459fc326dd3abbcf72c824e619f 397 Pfam PF07282 Putative transposase DNA-binding domain 314 378 1.3E-21 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal A616_RS27655 196bb683b57342e7b07dce5075c981b0 286 Pfam PF12679 ABC-2 family transporter protein 14 270 2.0E-12 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS22600 06dfc803f504ecfac91a1bcacad2ca87 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 110 5.6E-41 T 29-03-2018 IPR005562 SpoVA A616_RS22600 06dfc803f504ecfac91a1bcacad2ca87 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 4.2E-52 T 29-03-2018 IPR014204 Sporulation stage V, protein AE A616_RS26380 ce4e8144f10799215a6d767632c05398 297 Gene3D G3DSA:2.130.10.130 17 288 6.1E-4 T 29-03-2018 A616_RS26380 ce4e8144f10799215a6d767632c05398 297 SUPERFAMILY SSF69318 36 276 5.23E-8 T 29-03-2018 A616_RS18460 ebde0a1df18c598e10340fecafdbad0e 252 Pfam PF00561 alpha/beta hydrolase fold 33 157 1.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS18460 ebde0a1df18c598e10340fecafdbad0e 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS18460 ebde0a1df18c598e10340fecafdbad0e 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS18460 ebde0a1df18c598e10340fecafdbad0e 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS18460 ebde0a1df18c598e10340fecafdbad0e 252 SUPERFAMILY SSF53474 10 244 1.66E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS18460 ebde0a1df18c598e10340fecafdbad0e 252 Gene3D G3DSA:3.40.50.1820 1 249 2.3E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS25535 cb7fb78e5f9d5b0a6cb5c8724546f08f 228 SUPERFAMILY SSF51366 25 212 9.42E-6 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A616_RS25535 cb7fb78e5f9d5b0a6cb5c8724546f08f 228 Gene3D G3DSA:3.20.20.70 1 228 1.1E-10 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS09745 b0c831f9ca7779ea25beba2f0d99fd7a 320 Gene3D G3DSA:1.10.3470.10 2 289 6.4E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS09745 b0c831f9ca7779ea25beba2f0d99fd7a 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 287 1.4E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS14925 78c5af74fe89551ae2fd9cba677a343c 170 SUPERFAMILY SSF55729 5 157 1.58E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS14925 78c5af74fe89551ae2fd9cba677a343c 170 Pfam PF13302 Acetyltransferase (GNAT) domain 10 153 3.6E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS14925 78c5af74fe89551ae2fd9cba677a343c 170 Gene3D G3DSA:3.40.630.30 50 170 7.0E-11 T 29-03-2018 A616_RS26915 e6e672c6558b6534ddcef1e5147d8db8 218 Gene3D G3DSA:3.40.225.10 4 217 4.0E-43 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal A616_RS26915 e6e672c6558b6534ddcef1e5147d8db8 218 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 210 101.594 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 A616_RS26915 e6e672c6558b6534ddcef1e5147d8db8 218 SMART SM01007 13 202 4.2E-39 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal A616_RS26915 e6e672c6558b6534ddcef1e5147d8db8 218 SUPERFAMILY SSF53639 11 211 2.35E-45 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal A616_RS26915 e6e672c6558b6534ddcef1e5147d8db8 218 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 19 206 5.9E-67 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 A616_RS26915 e6e672c6558b6534ddcef1e5147d8db8 218 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 199 1.1E-37 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal A616_RS21105 6d898ab214778f2b95e732364218ee72 221 Gene3D G3DSA:1.20.1480.30 93 205 0.008 T 29-03-2018 A616_RS21105 6d898ab214778f2b95e732364218ee72 221 Pfam PF04012 PspA/IM30 family 2 217 6.7E-50 T 29-03-2018 IPR007157 PspA/IM30 A616_RS03995 5045a49518e1bfc9a108fd444867498b 267 Pfam PF00953 Glycosyl transferase family 4 21 185 1.4E-38 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS20900 4173d3b244cddd951c28b792ffcf41df 159 Pfam PF07301 Protein of unknown function (DUF1453) 11 151 7.0E-53 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 A616_RS20900 4173d3b244cddd951c28b792ffcf41df 159 PIRSF PIRSF021441 2 158 2.5E-55 T 29-03-2018 IPR031306 CcdC protein A616_RS02330 96af1895de0eb4c7262cc8962aa55cdc 209 Pfam PF13787 Protein of unknown function with HXXEE motif 38 151 3.0E-15 T 29-03-2018 IPR025671 Protein of unknown function with HXXEE motif A616_RS03960 c14def78550f4e52cc7b1623c160bfd6 349 Pfam PF04235 Protein of unknown function (DUF418) 169 343 8.6E-34 T 29-03-2018 IPR007349 Domain of unknown function DUF418 A616_RS21330 5c81d5db52fa80bf4d488b46eed51cd6 137 Hamap MF_00910 Cell division protein FtsL [ftsL]. 38 120 12.072 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A616_RS22985 07985fbbe4ead99c709e4d755541a170 102 Pfam PF02583 Metal-sensitive transcriptional repressor 21 99 1.2E-29 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A616_RS07185 ae86c4a7332bc056bfe72cbcb9faee14 242 SMART SM00382 26 213 1.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS07185 ae86c4a7332bc056bfe72cbcb9faee14 242 Gene3D G3DSA:3.40.50.300 1 240 1.2E-77 T 29-03-2018 A616_RS07185 ae86c4a7332bc056bfe72cbcb9faee14 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS07185 ae86c4a7332bc056bfe72cbcb9faee14 242 Pfam PF00005 ABC transporter 17 165 1.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS07185 ae86c4a7332bc056bfe72cbcb9faee14 242 PIRSF PIRSF039085 1 241 3.6E-114 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A616_RS07185 ae86c4a7332bc056bfe72cbcb9faee14 242 SUPERFAMILY SSF52540 1 234 2.52E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21080 76c266c78eb982f02740d3d0153c5a84 205 Gene3D G3DSA:1.10.10.60 1 35 2.5E-4 T 29-03-2018 A616_RS21080 76c266c78eb982f02740d3d0153c5a84 205 Pfam PF16258 Domain of unknown function (DUF4912) 58 174 5.2E-30 T 29-03-2018 IPR032585 Protein of unknown function DUF4912 A616_RS13610 eae9f86d695bc59f95d7efad7ffe0db0 224 PIRSF PIRSF016933 1 221 4.4E-76 T 29-03-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A616_RS13610 eae9f86d695bc59f95d7efad7ffe0db0 224 Pfam PF13367 Protease prsW family 28 199 7.3E-38 T 29-03-2018 IPR026898 Protease PrsW GO:0008233 A616_RS08775 6faba887d1f07223b882d2f282310245 257 Gene3D G3DSA:3.30.470.20 92 234 5.3E-11 T 29-03-2018 A616_RS08775 6faba887d1f07223b882d2f282310245 257 Pfam PF14398 YheC/D like ATP-grasp 5 245 2.1E-56 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS08775 6faba887d1f07223b882d2f282310245 257 Gene3D G3DSA:3.30.1490.20 28 91 2.4E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS08775 6faba887d1f07223b882d2f282310245 257 SUPERFAMILY SSF56059 20 220 2.12E-12 T 29-03-2018 A616_RS12915 cafa9f0fd5b10cd3e39d87d66cb1c97a 374 Pfam PF11079 Bacterial protein YqhG of unknown function 1 235 4.8E-62 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG A616_RS12915 cafa9f0fd5b10cd3e39d87d66cb1c97a 374 Gene3D G3DSA:1.20.1000.10 2 267 6.1E-4 T 29-03-2018 A616_RS12915 cafa9f0fd5b10cd3e39d87d66cb1c97a 374 ProDom PD123329 YQHG BH2818 6 229 1.0E-42 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG A616_RS27585 57edaae1bc382b7543a43371361649ef 393 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 223 384 5.9E-37 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS27585 57edaae1bc382b7543a43371361649ef 393 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 386 5.3E-99 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS11295 3982ca43401c07fa6bb5ff2af3c436ee 392 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 175 376 5.0E-57 T 29-03-2018 IPR010897 Sporulation stage II, protein P A616_RS11295 3982ca43401c07fa6bb5ff2af3c436ee 392 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 93 372 3.0E-64 T 29-03-2018 IPR010897 Sporulation stage II, protein P A616_RS11295 3982ca43401c07fa6bb5ff2af3c436ee 392 Gene3D G3DSA:3.40.630.40 171 381 9.8E-12 T 29-03-2018 A616_RS22200 302a3a2eac89775223646469add910b6 281 SMART SM00481 5 70 1.8E-20 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A616_RS22200 302a3a2eac89775223646469add910b6 281 SUPERFAMILY SSF89550 2 83 1.7E-50 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS22200 302a3a2eac89775223646469add910b6 281 SUPERFAMILY SSF89550 167 260 1.7E-50 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A616_RS22200 302a3a2eac89775223646469add910b6 281 Gene3D G3DSA:3.20.20.140 2 271 2.5E-50 T 29-03-2018 A616_RS22200 302a3a2eac89775223646469add910b6 281 Pfam PF02811 PHP domain 6 146 1.4E-13 T 29-03-2018 IPR004013 PHP domain GO:0003824 A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 Gene3D G3DSA:1.10.287.470 144 188 8.3E-8 T 29-03-2018 A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 199 404 2.9E-45 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 326 6.8E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 Gene3D G3DSA:2.40.50.100 61 143 3.2E-7 T 29-03-2018 A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 Gene3D G3DSA:2.40.50.100 215 390 5.6E-4 T 29-03-2018 A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 SUPERFAMILY SSF111369 200 331 8.5E-13 T 29-03-2018 A616_RS14065 3976bad10d8665c14176a7eb5eea147e 407 SUPERFAMILY SSF111369 52 150 1.01E-6 T 29-03-2018 A616_RS18150 3a48695106d2f58f1d84493680647acf 207 Pfam PF11211 Protein of unknown function (DUF2997) 150 192 3.4E-7 T 29-03-2018 IPR021375 Protein of unknown function DUF2997 A616_RS23855 dcee94d6890fe4117a02ac86541be7f6 260 Pfam PF00881 Nitroreductase family 68 243 2.1E-23 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS23855 dcee94d6890fe4117a02ac86541be7f6 260 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 82 247 1.2E-37 T 29-03-2018 IPR020051 SagB-type dehydrogenase domain A616_RS23855 dcee94d6890fe4117a02ac86541be7f6 260 SUPERFAMILY SSF55469 62 259 3.14E-27 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS23855 dcee94d6890fe4117a02ac86541be7f6 260 Gene3D G3DSA:3.40.109.10 2 248 3.6E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS19600 6a89b7a64f7988c0e397fe3d81a757c1 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 4.0E-32 T 29-03-2018 IPR007347 Sporulation stage V, protein S A616_RS19600 6a89b7a64f7988c0e397fe3d81a757c1 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 4.4E-40 T 29-03-2018 IPR007347 Sporulation stage V, protein S A616_RS23205 51b9bcda6bdad34b8b60d6dac1b16d58 746 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 381 706 1.5E-57 T 29-03-2018 IPR011749 Conserved hypothetical protein CHP02243 A616_RS23205 51b9bcda6bdad34b8b60d6dac1b16d58 746 Pfam PF04865 Baseplate J-like protein 484 666 5.0E-17 T 29-03-2018 IPR006949 Baseplate protein J-like A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 Pfam PF07833 Copper amine oxidase N-terminal domain 113 187 6.5E-6 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 Pfam PF07833 Copper amine oxidase N-terminal domain 71 142 5.8E-7 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 Gene3D G3DSA:3.30.457.10 20 65 0.0019 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 Gene3D G3DSA:3.30.457.10 66 124 4.7E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 Gene3D G3DSA:3.30.457.10 125 254 3.7E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 SUPERFAMILY SSF55383 85 137 3.27E-5 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal A616_RS23785 66001134d6b43c6a0462ab9d3d8fa589 265 Pfam PF14343 PrcB C-terminal 184 237 1.6E-9 T 29-03-2018 IPR025748 PrcB C-terminal domain A616_RS22465 44deb2c3344de0e3c1ae2bae1e897e4c 172 Pfam PF06803 Protein of unknown function (DUF1232) 81 116 1.5E-9 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 A616_RS17145 9fe6ed28982c3cfdfb58f6eab4f22ed0 113 Pfam PF08863 YolD-like protein 15 111 2.1E-11 T 29-03-2018 IPR014962 YolD-like protein A616_RS30845 791516b1785eb3bd3e2b01492c03bf72 285 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 64 284 1.3E-44 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS30845 791516b1785eb3bd3e2b01492c03bf72 285 Gene3D G3DSA:3.40.190.10 52 161 2.1E-29 T 29-03-2018 A616_RS30845 791516b1785eb3bd3e2b01492c03bf72 285 Gene3D G3DSA:3.40.190.10 162 245 5.6E-10 T 29-03-2018 A616_RS30845 791516b1785eb3bd3e2b01492c03bf72 285 SUPERFAMILY SSF53850 1 21 2.78E-51 T 29-03-2018 A616_RS30845 791516b1785eb3bd3e2b01492c03bf72 285 SUPERFAMILY SSF53850 52 284 2.78E-51 T 29-03-2018 A616_RS30845 791516b1785eb3bd3e2b01492c03bf72 285 SMART SM00062 62 285 1.8E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS11000 f4311b28049eb8af1cf58514476227f7 240 Pfam PF10099 Anti-sigma-K factor rskA 103 234 1.4E-11 T 29-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 A616_RS12715 1e90ad2710651ab0ee20ca3fe30eab8b 389 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 331 355 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A616_RS12715 1e90ad2710651ab0ee20ca3fe30eab8b 389 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 8 372 4.5E-110 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A616_RS12715 1e90ad2710651ab0ee20ca3fe30eab8b 389 Pfam PF01098 Cell cycle protein 11 373 8.3E-103 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A616_RS03375 37372e27d4b06deee4806ef9fc88bc32 574 Pfam PF08757 CotH kinase protein 132 451 3.9E-55 T 29-03-2018 IPR014867 Spore coat protein CotH A616_RS07105 bf8bb1e8f36dacd097a9bdcca6e6ab14 589 Pfam PF05569 BlaR1 peptidase M56 9 303 3.0E-65 T 29-03-2018 IPR008756 Peptidase M56 A616_RS07105 bf8bb1e8f36dacd097a9bdcca6e6ab14 589 SUPERFAMILY SSF56601 355 585 6.05E-37 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS07105 bf8bb1e8f36dacd097a9bdcca6e6ab14 589 Pfam PF00905 Penicillin binding protein transpeptidase domain 384 583 7.5E-39 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A616_RS07105 bf8bb1e8f36dacd097a9bdcca6e6ab14 589 Gene3D G3DSA:3.40.710.10 364 586 2.8E-29 T 29-03-2018 A616_RS06220 185ff28c520cf2cd85b975dbf8e38b6c 293 Pfam PF03837 RecT family 50 242 7.2E-53 T 29-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 A616_RS06220 185ff28c520cf2cd85b975dbf8e38b6c 293 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 9 241 7.4E-65 T 29-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 A616_RS23925 c18872c760abd198d6410f2000cb4641 275 Pfam PF12746 GNAT acetyltransferase 24 269 7.2E-48 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like A616_RS23925 c18872c760abd198d6410f2000cb4641 275 SUPERFAMILY SSF55729 126 266 3.48E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS23925 c18872c760abd198d6410f2000cb4641 275 Gene3D G3DSA:3.40.630.30 76 263 8.1E-12 T 29-03-2018 A616_RS06130 462f815504b31016009202befd7372bd 235 Pfam PF01794 Ferric reductase like transmembrane component 45 190 5.0E-9 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain A616_RS23910 15aca2f379b9bd24faf34a87f4ea3ab4 161 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 132 157 0.0028 T 29-03-2018 A616_RS09260 297d34f77edd9c4633958d682ca94d8f 212 Pfam PF01810 LysE type translocator 16 203 1.3E-32 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS09260 297d34f77edd9c4633958d682ca94d8f 212 PIRSF PIRSF006324 1 209 2.4E-58 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS12595 545a69a499128a45f10877e0fdf4735d 90 Pfam PF14069 Stage VI sporulation protein F 24 81 7.9E-10 T 29-03-2018 IPR025942 Stage VI sporulation protein F A616_RS17315 1f1f2ff869fe59256acb829a70caa7d0 345 SUPERFAMILY SSF56349 20 297 4.41E-25 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A616_RS17315 1f1f2ff869fe59256acb829a70caa7d0 345 Gene3D G3DSA:1.10.443.10 132 305 1.3E-15 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS17315 1f1f2ff869fe59256acb829a70caa7d0 345 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 21 105 3.7E-5 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A616_RS17315 1f1f2ff869fe59256acb829a70caa7d0 345 Pfam PF00589 Phage integrase family 134 295 2.7E-9 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A616_RS17315 1f1f2ff869fe59256acb829a70caa7d0 345 Gene3D G3DSA:1.10.150.130 6 113 1.7E-13 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal A616_RS14155 3df402f55bb5f84e69f0726571c43ef6 163 SUPERFAMILY SSF55811 5 127 2.17E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS14155 3df402f55bb5f84e69f0726571c43ef6 163 Pfam PF00293 NUDIX domain 8 106 2.4E-10 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A616_RS14155 3df402f55bb5f84e69f0726571c43ef6 163 Gene3D G3DSA:3.90.79.10 4 146 4.8E-17 T 29-03-2018 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 SUPERFAMILY SSF100879 236 341 8.24E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Pfam PF11799 impB/mucB/samB family C-terminal domain 232 340 4.0E-12 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Hamap MF_01113 DNA polymerase IV [dinB]. 1 343 34.175 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Pfam PF00817 impB/mucB/samB family 7 149 6.5E-46 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Gene3D G3DSA:1.10.150.20 166 237 1.2E-15 T 29-03-2018 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Gene3D G3DSA:3.30.70.270 114 165 2.6E-16 T 29-03-2018 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Gene3D G3DSA:3.30.70.270 40 113 2.8E-22 T 29-03-2018 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 Gene3D G3DSA:3.30.1490.100 238 344 5.8E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A616_RS11180 2fbc49adb9f2a9a1e340a8d6a33321c2 350 SUPERFAMILY SSF56672 2 229 9.78E-82 T 29-03-2018 A616_RS02775 5c17490850ec70400dbad75c08c37c25 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 292 2.4E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS02775 5c17490850ec70400dbad75c08c37c25 296 Gene3D G3DSA:1.10.3720.10 1 281 2.5E-43 T 29-03-2018 A616_RS02775 5c17490850ec70400dbad75c08c37c25 296 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 9 285 9.4E-88 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A616_RS02775 5c17490850ec70400dbad75c08c37c25 296 SUPERFAMILY SSF161098 14 278 1.57E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14210 7e657449d49d1997234457c36a876f16 278 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 11 269 3.5E-98 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 A616_RS14210 7e657449d49d1997234457c36a876f16 278 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 11 273 4.0E-127 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 A616_RS14210 7e657449d49d1997234457c36a876f16 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 268 5.2E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14210 7e657449d49d1997234457c36a876f16 278 Gene3D G3DSA:1.10.3720.10 4 277 1.3E-45 T 29-03-2018 A616_RS14210 7e657449d49d1997234457c36a876f16 278 SUPERFAMILY SSF161098 19 267 7.01E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14525 494a89b803fa6a8d17a9a5544a8f51e3 277 PIRSF PIRSF018982 24 276 8.9E-80 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS14525 494a89b803fa6a8d17a9a5544a8f51e3 277 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 43 269 7.3E-76 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 A616_RS25125 a58e69226c7deec8e796a6bd97df1b00 121 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 12 100 3.0E-12 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 A616_RS25125 a58e69226c7deec8e796a6bd97df1b00 121 Pfam PF07457 Protein of unknown function (DUF1516) 11 116 1.5E-28 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 A616_RS22565 1692b7cc764469883462ed934360a0f7 147 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 12 140 3.0E-22 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A616_RS22565 1692b7cc764469883462ed934360a0f7 147 Gene3D G3DSA:3.10.490.10 4 147 2.3E-26 T 29-03-2018 A616_RS22565 1692b7cc764469883462ed934360a0f7 147 SUPERFAMILY SSF110857 10 143 3.53E-19 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like A616_RS11080 7a69ec7a7b7b70e91b2260b27e2eede2 203 Pfam PF02630 SCO1/SenC 44 181 2.3E-19 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A616_RS11080 7a69ec7a7b7b70e91b2260b27e2eede2 203 Gene3D G3DSA:3.40.30.10 35 199 1.5E-26 T 29-03-2018 A616_RS11080 7a69ec7a7b7b70e91b2260b27e2eede2 203 SUPERFAMILY SSF52833 40 201 1.95E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS28630 41f836b0c023c23cc48c68908ce5d116 351 SUPERFAMILY SSF53383 5 347 5.28E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A616_RS28630 41f836b0c023c23cc48c68908ce5d116 351 Gene3D G3DSA:3.90.1150.10 256 348 1.9E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A616_RS28630 41f836b0c023c23cc48c68908ce5d116 351 PIRSF PIRSF017617 1 350 5.8E-123 T 29-03-2018 IPR023603 Threonine aldolase A616_RS28630 41f836b0c023c23cc48c68908ce5d116 351 Gene3D G3DSA:3.40.640.10 20 255 3.5E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A616_RS28630 41f836b0c023c23cc48c68908ce5d116 351 Pfam PF01212 Beta-eliminating lyase 7 292 5.2E-87 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A616_RS08600 7360ad31e863f0f357cad3d47b9ae1dc 110 SUPERFAMILY SSF46785 3 98 9.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08600 7360ad31e863f0f357cad3d47b9ae1dc 110 Gene3D G3DSA:1.10.10.10 2 109 1.5E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS08600 7360ad31e863f0f357cad3d47b9ae1dc 110 Pfam PF03551 Transcriptional regulator PadR-like family 16 89 9.2E-26 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS17530 ffcf86e74a43ccd5e370d0271471ead1 103 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 8 97 2.5E-16 T 29-03-2018 IPR010026 Phage holin, LL-H family A616_RS17530 ffcf86e74a43ccd5e370d0271471ead1 103 TIGRFAM TIGR01673 holin_LLH: phage holin, LL-H family 37 97 4.2E-9 T 29-03-2018 IPR010026 Phage holin, LL-H family A616_RS17530 ffcf86e74a43ccd5e370d0271471ead1 103 Gene3D G3DSA:3.40.630.10 32 94 2.1E-4 T 29-03-2018 A616_RS03490 95f342365a873da3b5a0b92250aa0a2a 258 Pfam PF02596 Uncharacterised ArCR, COG2043 10 219 8.6E-47 T 29-03-2018 IPR003748 Protein of unknown function DUF169 A616_RS23210 eb6e0d14f1bc728dc411b35969a2d78c 1024 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 705 976 5.6E-61 T 29-03-2018 IPR011749 Conserved hypothetical protein CHP02243 A616_RS23210 eb6e0d14f1bc728dc411b35969a2d78c 1024 Pfam PF04865 Baseplate J-like protein 763 912 1.4E-10 T 29-03-2018 IPR006949 Baseplate protein J-like A616_RS06870 e7c0a829190499b3dea166ba0f294625 306 SUPERFAMILY SSF46785 212 301 6.03E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06870 e7c0a829190499b3dea166ba0f294625 306 Pfam PF12840 Helix-turn-helix domain 222 272 2.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS06870 e7c0a829190499b3dea166ba0f294625 306 SMART SM00418 217 299 1.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS06870 e7c0a829190499b3dea166ba0f294625 306 Gene3D G3DSA:1.10.10.10 207 292 5.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04975 dbbad57af11a57c425013597125af351 200 Gene3D G3DSA:2.30.110.10 9 188 1.6E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS04975 dbbad57af11a57c425013597125af351 200 Pfam PF01613 Flavin reductase like domain 14 188 2.8E-8 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 A616_RS04975 dbbad57af11a57c425013597125af351 200 SUPERFAMILY SSF50475 9 193 8.39E-30 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A616_RS27090 04f8d9c8a4c2042e1e7b104e010e66ce 129 Gene3D G3DSA:2.60.40.420 27 129 6.2E-10 T 29-03-2018 IPR008972 Cupredoxin A616_RS27090 04f8d9c8a4c2042e1e7b104e010e66ce 129 SUPERFAMILY SSF49503 10 128 3.17E-13 T 29-03-2018 IPR008972 Cupredoxin A616_RS27090 04f8d9c8a4c2042e1e7b104e010e66ce 129 Pfam PF13473 Cupredoxin-like domain 13 128 4.1E-21 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain A616_RS27245 61fba96a940302638135257c4387e9a9 137 Pfam PF00575 S1 RNA binding domain 4 74 2.0E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 A616_RS27245 61fba96a940302638135257c4387e9a9 137 SUPERFAMILY SSF50249 4 87 8.21E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS27245 61fba96a940302638135257c4387e9a9 137 SMART SM00316 4 74 5.6E-22 T 29-03-2018 IPR022967 RNA-binding domain, S1 A616_RS27245 61fba96a940302638135257c4387e9a9 137 Gene3D G3DSA:2.40.50.140 6 135 8.6E-25 T 29-03-2018 A616_RS07325 f83e7e5357596e275ef44d6d2e48fd5c 312 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 255 275 - T 29-03-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A616_RS07325 f83e7e5357596e275ef44d6d2e48fd5c 312 Gene3D G3DSA:3.40.50.1400 1 107 1.5E-26 T 29-03-2018 A616_RS07325 f83e7e5357596e275ef44d6d2e48fd5c 312 Gene3D G3DSA:3.40.50.1400 108 234 3.9E-27 T 29-03-2018 A616_RS07325 f83e7e5357596e275ef44d6d2e48fd5c 312 Pfam PF01903 CbiX 9 112 8.3E-28 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A616_RS07325 f83e7e5357596e275ef44d6d2e48fd5c 312 Pfam PF01903 CbiX 137 241 1.9E-25 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 A616_RS07325 f83e7e5357596e275ef44d6d2e48fd5c 312 SUPERFAMILY SSF53800 1 247 1.42E-53 T 29-03-2018 A616_RS07980 83b065315a135e51af1b4ad40c54ebde 131 Pfam PF04186 FxsA cytoplasmic membrane protein 8 115 5.2E-37 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 SUPERFAMILY SSF55486 11 500 8.52E-120 T 29-03-2018 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 233 249 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 250 269 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 338 357 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 407 428 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 153 173 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 270 289 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 297 313 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 384 401 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 452 470 5.8E-76 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 5 500 1.2E-173 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 Gene3D G3DSA:1.10.1370.10 60 505 6.3E-42 T 29-03-2018 A616_RS12450 4b0d3f9d6830664060ffd3c21fc40f06 506 PIRSF PIRSF006615 4 506 8.9E-199 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A616_RS28055 14a3c1ba3bf12ea83d54a37c97a71958 214 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 7 110 1.6E-10 T 29-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 A616_RS10580 69c1cbbdaaac3cc29ec67f1538f153cb 221 Gene3D G3DSA:2.40.10.220 118 219 6.2E-5 T 29-03-2018 A616_RS25095 a2006fa1d28f2eaac09de9ff92f29e8e 329 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 150 313 1.2E-53 T 29-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal A616_RS25095 a2006fa1d28f2eaac09de9ff92f29e8e 329 Pfam PF06081 Aromatic acid exporter family member 1 6 146 7.5E-49 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 A616_RS25455 d7fde9473e8fa4704aed0fec8300b2ec 172 Gene3D G3DSA:3.10.129.10 4 161 9.9E-48 T 29-03-2018 A616_RS25455 d7fde9473e8fa4704aed0fec8300b2ec 172 SUPERFAMILY SSF54637 6 155 4.59E-45 T 29-03-2018 IPR029069 HotDog domain A616_RS25455 d7fde9473e8fa4704aed0fec8300b2ec 172 Pfam PF03061 Thioesterase superfamily 28 99 1.3E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A616_RS13570 6840d04fc1a16acf008766010c81bf26 192 Pfam PF02517 CAAX protease self-immunity 95 176 4.2E-12 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A616_RS08130 b7ba0f454dfc355ada02eec6bace9b13 369 Pfam PF01757 Acyltransferase family 6 347 1.0E-35 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS28060 588fe0ff70209a1bc9409f5e470ecdb3 271 Pfam PF04865 Baseplate J-like protein 96 232 6.0E-18 T 29-03-2018 IPR006949 Baseplate protein J-like A616_RS14165 15785683790f4020d2c7b85043d59667 248 Gene3D G3DSA:3.40.50.150 32 245 9.6E-37 T 29-03-2018 A616_RS14165 15785683790f4020d2c7b85043d59667 248 SUPERFAMILY SSF53335 6 238 4.14E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS14165 15785683790f4020d2c7b85043d59667 248 Pfam PF08241 Methyltransferase domain 47 140 3.8E-22 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A616_RS20110 8aa6d6cbc31f6b7ce17f1a0e1fbf8895 297 Pfam PF04326 Putative DNA-binding domain 147 268 1.9E-17 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 SMART SM00418 14 94 1.0E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 Gene3D G3DSA:1.10.10.10 5 88 1.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 Pfam PF12840 Helix-turn-helix domain 16 73 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 3.2E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 3.2E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 3.2E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS17810 c0bdf531c0ef2e650a9ef123ffb825d9 96 SUPERFAMILY SSF46785 6 94 5.92E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15175 ff622536f65f323dacd5c154f0de7811 310 Pfam PF00072 Response regulator receiver domain 5 114 2.9E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS15175 ff622536f65f323dacd5c154f0de7811 310 SMART SM00448 1 114 1.5E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS15175 ff622536f65f323dacd5c154f0de7811 310 SUPERFAMILY SSF52172 5 134 1.22E-22 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS15175 ff622536f65f323dacd5c154f0de7811 310 Gene3D G3DSA:3.40.50.2300 3 139 1.7E-20 T 29-03-2018 A616_RS15175 ff622536f65f323dacd5c154f0de7811 310 Pfam PF08664 YcbB domain 160 299 9.5E-47 T 29-03-2018 IPR013972 YcbB domain A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 257 5.9E-71 T 29-03-2018 A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 182 0.0044 T 29-03-2018 A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 Gene3D G3DSA:3.40.50.720 5 50 1.1E-12 T 29-03-2018 A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 Gene3D G3DSA:3.40.50.720 51 260 1.2E-63 T 29-03-2018 A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 SUPERFAMILY SSF51735 11 257 7.73E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS31510 9fffd34495ede41df0b3e098acd21f99 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A616_RS30440 d0aa3ab09db35331721723588c1ce539 142 SUPERFAMILY SSF55729 3 140 4.75E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS30440 d0aa3ab09db35331721723588c1ce539 142 Pfam PF00583 Acetyltransferase (GNAT) family 43 119 5.8E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS30440 d0aa3ab09db35331721723588c1ce539 142 Gene3D G3DSA:3.40.630.30 38 141 1.0E-17 T 29-03-2018 A616_RS20815 be47e0df78cf8f9bff29c94df4e146f7 294 Pfam PF03755 YicC-like family, N-terminal region 2 156 5.4E-40 T 29-03-2018 IPR013527 YicC-like, N-terminal A616_RS20815 be47e0df78cf8f9bff29c94df4e146f7 294 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 294 8.5E-85 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 A616_RS20815 be47e0df78cf8f9bff29c94df4e146f7 294 Pfam PF08340 Domain of unknown function (DUF1732) 210 294 6.0E-36 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 A616_RS10710 a8e46a105b1e2031bf50f88e06f7b4dc 78 Pfam PF13797 Post-transcriptional regulator 7 77 9.4E-22 T 29-03-2018 IPR025716 Post-transcriptional regulator A616_RS10780 98d940a054f7435e2c7b47dd5efe7aa0 251 SUPERFAMILY SSF69572 4 244 2.62E-60 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS10780 98d940a054f7435e2c7b47dd5efe7aa0 251 Pfam PF00899 ThiF family 11 157 1.2E-39 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS10780 98d940a054f7435e2c7b47dd5efe7aa0 251 Gene3D G3DSA:3.40.50.720 2 246 6.6E-44 T 29-03-2018 A616_RS18930 621044cca52e5b8682fdf52b1519511b 149 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 2 147 19.03 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS18930 621044cca52e5b8682fdf52b1519511b 149 Pfam PF04284 Protein of unknown function (DUF441) 6 144 8.1E-47 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS18930 621044cca52e5b8682fdf52b1519511b 149 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 19 129 1.0E-16 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame A616_RS25490 6c075ba2d9381b23f52dd9a1500cf1a8 142 SUPERFAMILY SSF103481 39 140 9.81E-5 T 29-03-2018 A616_RS25490 6c075ba2d9381b23f52dd9a1500cf1a8 142 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 3.8E-34 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ A616_RS25625 878d17d39d91fbdbe56eb317acbecb8c 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 316 9.3E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS25625 878d17d39d91fbdbe56eb317acbecb8c 318 Gene3D G3DSA:1.10.3720.10 2 305 4.5E-42 T 29-03-2018 A616_RS25625 878d17d39d91fbdbe56eb317acbecb8c 318 SUPERFAMILY SSF161098 89 304 1.7E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS22615 996f37e0cc8be1bd835da43c51da0331 286 Gene3D G3DSA:3.30.240.20 171 225 7.8E-12 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A616_RS22615 996f37e0cc8be1bd835da43c51da0331 286 Gene3D G3DSA:3.30.240.20 82 151 3.3E-25 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A616_RS22615 996f37e0cc8be1bd835da43c51da0331 286 Pfam PF04239 Protein of unknown function (DUF421) 89 204 3.9E-34 T 29-03-2018 IPR007353 Protein of unknown function DUF421 A616_RS22615 996f37e0cc8be1bd835da43c51da0331 286 Pfam PF07870 Protein of unknown function (DUF1657) 236 282 2.0E-17 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 A616_RS14665 aebabe069fd2f405845106770307b93f 1066 SUPERFAMILY SSF53187 711 897 5.95E-23 T 29-03-2018 A616_RS14665 aebabe069fd2f405845106770307b93f 1066 Gene3D G3DSA:3.40.630.10 701 977 7.5E-20 T 29-03-2018 A616_RS14665 aebabe069fd2f405845106770307b93f 1066 Pfam PF00246 Zinc carboxypeptidase 717 831 2.4E-13 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 A616_RS11150 c5e241d58c413fb1fb109b711365bc11 431 SUPERFAMILY SSF51905 1 293 2.1E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS11150 c5e241d58c413fb1fb109b711365bc11 431 SUPERFAMILY SSF51905 390 429 2.1E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS11150 c5e241d58c413fb1fb109b711365bc11 431 Gene3D G3DSA:3.50.50.60 1 430 1.7E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS11150 c5e241d58c413fb1fb109b711365bc11 431 Pfam PF01593 Flavin containing amine oxidoreductase 15 427 5.6E-23 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A616_RS07625 6dd18cd1318bc194e12d4684cc60d771 178 Pfam PF13787 Protein of unknown function with HXXEE motif 9 133 7.8E-22 T 29-03-2018 IPR025671 Protein of unknown function with HXXEE motif A616_RS03405 720c09577c277630efd075c3669bc72a 151 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 81 92 2.2E-5 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A616_RS03405 720c09577c277630efd075c3669bc72a 151 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 93 108 2.2E-5 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A616_RS03405 720c09577c277630efd075c3669bc72a 151 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 18 35 2.2E-5 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A616_RS03405 720c09577c277630efd075c3669bc72a 151 Pfam PF01478 Type IV leader peptidase family 12 111 4.4E-17 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A616_RS18250 037ea0201c8bf10d3038ff391e57c1b9 350 SUPERFAMILY SSF56266 3 349 2.2E-91 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS18250 037ea0201c8bf10d3038ff391e57c1b9 350 Pfam PF03576 Peptidase family S58 22 335 1.5E-105 T 29-03-2018 IPR005321 Peptidase S58, DmpA A616_RS18250 037ea0201c8bf10d3038ff391e57c1b9 350 Gene3D G3DSA:3.60.70.12 4 350 2.1E-105 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A616_RS12815 fbb7fb3999ed3151f768b14efefe7a50 75 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 5 64 3.0E-13 T 29-03-2018 IPR020256 Spore coat protein CotJA A616_RS12815 fbb7fb3999ed3151f768b14efefe7a50 75 Pfam PF11007 Spore coat associated protein JA (CotJA) 29 63 1.2E-10 T 29-03-2018 IPR020256 Spore coat protein CotJA A616_RS21115 4c305faf1f5c5c05e4e74afb77004f24 377 Pfam PF10720 Protein of unknown function (DUF2515) 36 370 2.0E-127 T 29-03-2018 IPR019658 Protein of unknown function DUF2515 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 121 129 5.6E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 160 184 5.6E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 5.6E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 SUPERFAMILY SSF51905 164 326 3.17E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 Gene3D G3DSA:3.50.50.60 178 346 8.2E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 Gene3D G3DSA:3.40.50.720 151 177 0.2 T 29-03-2018 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 Gene3D G3DSA:3.50.50.60 1 150 1.7E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 184 8.6E-31 T 29-03-2018 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.4E-9 T 29-03-2018 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 7.4E-9 T 29-03-2018 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 7.4E-9 T 29-03-2018 A616_RS11965 65388a66c199b50eaaf97aa09c2f89ea 346 SUPERFAMILY SSF51905 1 184 3.35E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS12375 e44fb3feeb3d470fa947566e6e18bcce 221 SUPERFAMILY SSF161098 16 202 1.3E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12375 e44fb3feeb3d470fa947566e6e18bcce 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 1.1E-25 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A616_RS12375 e44fb3feeb3d470fa947566e6e18bcce 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 217 3.8E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS12375 e44fb3feeb3d470fa947566e6e18bcce 221 Gene3D G3DSA:1.10.3720.10 13 219 1.7E-46 T 29-03-2018 A616_RS07870 01cb06a60f73fb156cb563823380657e 435 Pfam PF14398 YheC/D like ATP-grasp 175 422 7.4E-78 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS07870 01cb06a60f73fb156cb563823380657e 435 SUPERFAMILY SSF56059 182 400 1.38E-11 T 29-03-2018 A616_RS07870 01cb06a60f73fb156cb563823380657e 435 Gene3D G3DSA:3.30.470.20 277 407 4.1E-12 T 29-03-2018 A616_RS07870 01cb06a60f73fb156cb563823380657e 435 Gene3D G3DSA:3.30.1490.20 208 276 2.2E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS14895 b17bc42db1c52e51d94c3c135a367a81 305 Pfam PF01040 UbiA prenyltransferase family 31 282 3.7E-58 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A616_RS14895 b17bc42db1c52e51d94c3c135a367a81 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 14 298 17.333 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A616_RS14895 b17bc42db1c52e51d94c3c135a367a81 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 18 295 6.6E-85 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 A616_RS14895 b17bc42db1c52e51d94c3c135a367a81 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 74 96 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site A616_RS13310 7d5d81b6f96ad0f3ad46ee3468622dbd 46 Pfam PF13072 Protein of unknown function (DUF3936) 1 29 4.6E-10 T 29-03-2018 IPR025177 Protein of unknown function DUF3936 A616_RS15300 45c6c841d1c7791eae83bbb5d4783e0b 164 Pfam PF07563 Protein of unknown function (DUF1541) 106 157 1.5E-22 T 29-03-2018 IPR011438 Domain of unknown function DUF1541 A616_RS15300 45c6c841d1c7791eae83bbb5d4783e0b 164 Pfam PF07563 Protein of unknown function (DUF1541) 42 93 2.3E-23 T 29-03-2018 IPR011438 Domain of unknown function DUF1541 A616_RS15300 45c6c841d1c7791eae83bbb5d4783e0b 164 Gene3D G3DSA:3.40.190.10 1 153 5.7E-4 T 29-03-2018 A616_RS09760 a2c763f7db99e1a08893215525ada3af 83 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 76 3.7E-28 T 29-03-2018 IPR018680 Protein of unknown function DUF2164 A616_RS20335 a13cd7d7f09e60dfdd6d29139e007f47 172 Pfam PF02620 Uncharacterized ACR, COG1399 55 167 5.9E-30 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD A616_RS31275 79074410da0112340ef717b019368ca4 587 Pfam PF08239 Bacterial SH3 domain 540 582 1.3E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type A616_RS31275 79074410da0112340ef717b019368ca4 587 Gene3D G3DSA:1.25.40.10 37 441 0.0022 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS31275 79074410da0112340ef717b019368ca4 587 Gene3D G3DSA:2.40.50.110 500 583 1.1E-7 T 29-03-2018 A616_RS12905 c9e505e8f599fb13b20a04961ba323de 84 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 45 9.0E-5 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 A616_RS12905 c9e505e8f599fb13b20a04961ba323de 84 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 77 5.4E-26 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 A616_RS00595 0ef2b783be401f46559aef3475bfcd90 255 Pfam PF05175 Methyltransferase small domain 38 177 2.0E-13 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A616_RS00595 0ef2b783be401f46559aef3475bfcd90 255 SUPERFAMILY SSF53335 18 202 9.07E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS00595 0ef2b783be401f46559aef3475bfcd90 255 Gene3D G3DSA:3.40.50.150 13 254 9.0E-39 T 29-03-2018 A616_RS30120 ba571b0189069c5c63f6b40a7f2abc46 186 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 11 185 13.558 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 A616_RS30120 ba571b0189069c5c63f6b40a7f2abc46 186 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 16 83 6.4E-8 T 29-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 A616_RS30120 ba571b0189069c5c63f6b40a7f2abc46 186 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 14 92 5.1E-32 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 A616_RS22325 da8fa48e4cdaf4267e916173394d2cda 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 285 4.3E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS22325 da8fa48e4cdaf4267e916173394d2cda 311 Gene3D G3DSA:1.10.3470.10 3 292 1.1E-33 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS30560 ada6174a5d0370f2f18e6d14a8eaf140 145 Gene3D G3DSA:2.60.120.380 19 145 3.0E-13 T 29-03-2018 A616_RS24450 6451fc0dc2184b175840f03d6c5affd2 259 Pfam PF00975 Thioesterase domain 22 241 1.1E-49 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 A616_RS24450 6451fc0dc2184b175840f03d6c5affd2 259 SUPERFAMILY SSF53474 8 245 8.11E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS24450 6451fc0dc2184b175840f03d6c5affd2 259 Gene3D G3DSA:3.40.50.1820 1 249 5.9E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS16845 1b105ce252785a54544349008094f551 116 Pfam PF12844 Helix-turn-helix domain 6 62 2.8E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16845 1b105ce252785a54544349008094f551 116 SUPERFAMILY SSF47413 1 65 2.13E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS16845 1b105ce252785a54544349008094f551 116 SMART SM00530 6 62 5.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS16845 1b105ce252785a54544349008094f551 116 Gene3D G3DSA:1.10.260.40 1 85 2.6E-11 T 29-03-2018 A616_RS24430 41a08588eb0b22346178ac080d17f381 371 SUPERFAMILY SSF51735 4 144 3.06E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS24430 41a08588eb0b22346178ac080d17f381 371 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 6 127 2.5E-16 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A616_RS24430 41a08588eb0b22346178ac080d17f381 371 Gene3D G3DSA:3.40.50.720 2 148 1.4E-18 T 29-03-2018 A616_RS18895 6499685a6a111ed87d21faaa9331f945 358 SUPERFAMILY SSF82171 117 346 8.63E-15 T 29-03-2018 A616_RS18895 6499685a6a111ed87d21faaa9331f945 358 Gene3D G3DSA:2.140.10.30 246 356 3.0E-6 T 29-03-2018 A616_RS18895 6499685a6a111ed87d21faaa9331f945 358 Gene3D G3DSA:2.140.10.30 90 245 3.5E-9 T 29-03-2018 A616_RS08390 7d8473682c561e00c42a84d2e252ee51 363 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 239 311 7.4E-16 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal A616_RS08390 7d8473682c561e00c42a84d2e252ee51 363 Pfam PF01385 Probable transposase 166 270 5.1E-28 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A616_RS08390 7d8473682c561e00c42a84d2e252ee51 363 Pfam PF12323 Helix-turn-helix domain 2 46 2.0E-21 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain A616_RS08390 7d8473682c561e00c42a84d2e252ee51 363 Pfam PF07282 Putative transposase DNA-binding domain 284 356 1.4E-22 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal A616_RS00335 4f9c8a30053f77c9336da709c3f02232 136 Pfam PF07681 DoxX 9 87 4.0E-19 T 29-03-2018 IPR032808 DoxX family A616_RS31625 5894b1980137412c8fc1be178976cf26 233 Gene3D G3DSA:3.90.550.10 5 184 1.6E-12 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31625 5894b1980137412c8fc1be178976cf26 233 SUPERFAMILY SSF53448 5 192 1.88E-15 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS31625 5894b1980137412c8fc1be178976cf26 233 Pfam PF13704 Glycosyl transferase family 2 18 108 3.7E-9 T 29-03-2018 A616_RS28095 89e6c6e82feb212b12386b8e4a800e22 150 SUPERFAMILY SSF69279 16 122 2.38E-5 T 29-03-2018 A616_RS23240 cee0c56ff388d35eef9375a6ee080866 154 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 21 151 1.3E-37 T 29-03-2018 IPR011747 Conserved hypothetical protein CHP02241 A616_RS23240 cee0c56ff388d35eef9375a6ee080866 154 Pfam PF06841 T4-like virus tail tube protein gp19 11 151 2.3E-38 T 29-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 A616_RS03945 e683a65357ecf70ebdc25260bf0a7efb 348 Gene3D G3DSA:3.40.50.2300 41 148 6.5E-16 T 29-03-2018 A616_RS03945 e683a65357ecf70ebdc25260bf0a7efb 348 Gene3D G3DSA:3.40.50.2300 149 348 3.4E-39 T 29-03-2018 A616_RS03945 e683a65357ecf70ebdc25260bf0a7efb 348 SUPERFAMILY SSF53822 41 346 3.53E-77 T 29-03-2018 IPR028082 Periplasmic binding protein-like I A616_RS03945 e683a65357ecf70ebdc25260bf0a7efb 348 Pfam PF13407 Periplasmic binding protein domain 43 315 3.6E-58 T 29-03-2018 IPR025997 Periplasmic binding protein A616_RS03165 6a37c7d1e11713394a249329fe0bc889 401 Pfam PF01882 Protein of unknown function DUF58 196 277 1.2E-19 T 29-03-2018 IPR002881 Domain of unknown function DUF58 A616_RS13070 2d7dba6d6dfc7e00a9451e01921f8ede 394 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 6 387 1.6E-127 T 29-03-2018 IPR014194 Sporulation stage III, protein AE A616_RS13070 2d7dba6d6dfc7e00a9451e01921f8ede 394 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 72 387 1.3E-103 T 29-03-2018 IPR014194 Sporulation stage III, protein AE A616_RS11045 d45d5bcd3eb8a2f951834a01f6aa82a0 155 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 138 2.9E-25 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ A616_RS30420 31301a33657c17f64c6914c024f700dc 271 SUPERFAMILY SSF52540 3 234 7.28E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS30420 31301a33657c17f64c6914c024f700dc 271 SMART SM00382 30 215 3.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS30420 31301a33657c17f64c6914c024f700dc 271 Pfam PF00005 ABC transporter 21 166 8.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS30420 31301a33657c17f64c6914c024f700dc 271 Gene3D G3DSA:3.40.50.300 1 242 1.9E-67 T 29-03-2018 A616_RS12540 17d7365b8b0643603c6f689fa26d78a4 147 ProDom PD086666 YNEK BH2332 13 144 7.0E-48 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK A616_RS12540 17d7365b8b0643603c6f689fa26d78a4 147 Pfam PF11084 Protein of unknown function (DUF2621) 7 143 9.5E-70 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK A616_RS18290 9a261cfd25c1df072a455a2efe2a9eec 163 Gene3D G3DSA:3.40.630.30 1 163 1.6E-21 T 29-03-2018 A616_RS18290 9a261cfd25c1df072a455a2efe2a9eec 163 SUPERFAMILY SSF55729 4 145 2.48E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS18290 9a261cfd25c1df072a455a2efe2a9eec 163 Pfam PF13302 Acetyltransferase (GNAT) domain 9 138 1.9E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS12630 6b3f1ad61dcccdbf4629218fcb3da2bf 462 PIRSF PIRSF006060 1 461 1.9E-83 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS12630 6b3f1ad61dcccdbf4629218fcb3da2bf 462 Pfam PF00324 Amino acid permease 20 460 2.1E-122 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A616_RS12630 6b3f1ad61dcccdbf4629218fcb3da2bf 462 ProSitePatterns PS00218 Amino acid permeases signature. 45 76 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 A616_RS09815 eb3e8088a013bc791bee642d42e90362 174 Gene3D G3DSA:3.40.630.30 10 162 9.6E-4 T 29-03-2018 A616_RS31390 3927439abdfa4dc466e6a5d2329b6890 425 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 9 425 1.0E-158 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 A616_RS31390 3927439abdfa4dc466e6a5d2329b6890 425 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 68 414 8.0E-94 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A616_RS31390 3927439abdfa4dc466e6a5d2329b6890 425 Pfam PF04261 Dyp-type peroxidase family 68 415 1.6E-104 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A616_RS31390 3927439abdfa4dc466e6a5d2329b6890 425 SUPERFAMILY SSF54909 63 420 5.36E-91 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS21435 1ee325c5ce944ca405ef6935bfd04456 88 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 78 1.0E-11 T 29-03-2018 IPR020254 Protein of unknown function DUF2626 A616_RS21435 1ee325c5ce944ca405ef6935bfd04456 88 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 7.7E-31 T 29-03-2018 IPR020254 Protein of unknown function DUF2626 A616_RS12120 de77ef20d6373df501fd9d63f8cf7a4d 510 PIRSF PIRSF006060 10 505 1.1E-57 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS12120 de77ef20d6373df501fd9d63f8cf7a4d 510 Pfam PF13520 Amino acid permease 32 476 1.8E-47 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS15030 2116c47c3fc7743e697b71297f60906d 338 Pfam PF00296 Luciferase-like monooxygenase 16 302 1.3E-35 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS15030 2116c47c3fc7743e697b71297f60906d 338 SUPERFAMILY SSF51679 3 330 1.17E-67 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS15030 2116c47c3fc7743e697b71297f60906d 338 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 330 3.4E-112 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 A616_RS15030 2116c47c3fc7743e697b71297f60906d 338 Gene3D G3DSA:3.20.20.30 3 333 1.1E-65 T 29-03-2018 A616_RS27975 5b1a3cd19c712c248f1c885b0662e640 68 Pfam PF14169 Cold-inducible protein YdjO 2 59 3.9E-29 T 29-03-2018 IPR025916 Cold-inducible protein YdjO A616_RS17865 7cb17a3b8b5dc9e509b4e6ea537aa09c 71 Pfam PF13701 Transposase DDE domain group 1 8 71 1.7E-11 T 29-03-2018 IPR025668 Transposase DDE domain A616_RS30470 e0906f9a4af15e109b67f3fffbcab41f 239 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 220 3.4E-35 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A616_RS30470 e0906f9a4af15e109b67f3fffbcab41f 239 SUPERFAMILY SSF51695 3 238 1.1E-68 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS30470 e0906f9a4af15e109b67f3fffbcab41f 239 Gene3D G3DSA:3.20.20.190 2 239 1.2E-67 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A616_RS04400 06ea32bbf407d317c391c770c3276912 376 Pfam PF12698 ABC-2 family transporter protein 18 364 3.0E-25 T 29-03-2018 A616_RS13420 e3bd08ea64cfeb233a86ac9a8441abfa 139 Pfam PF13782 Stage V sporulation protein AB 28 136 1.4E-34 T 29-03-2018 IPR020144 Stage V sporulation protein AB A616_RS13420 e3bd08ea64cfeb233a86ac9a8441abfa 139 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 27 137 4.0E-23 T 29-03-2018 IPR020144 Stage V sporulation protein AB A616_RS19655 7c19d3e834f5c9019b5eaa4034175dd3 89 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 2.7E-34 T 29-03-2018 IPR021637 Protein of unknown function DUF3243 A616_RS19655 7c19d3e834f5c9019b5eaa4034175dd3 89 PIRSF PIRSF004764 1 84 8.2E-31 T 29-03-2018 IPR024702 Uncharacterised conserved protein YmfJ A616_RS06510 b9fcb1395bc9de63b837dc8936441eb4 81 Pfam PF08863 YolD-like protein 6 79 1.8E-7 T 29-03-2018 IPR014962 YolD-like protein A616_RS20115 f900446b215999cc1fa9a8f007edd534 112 Gene3D G3DSA:3.30.1050.10 1 108 1.7E-21 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS20115 f900446b215999cc1fa9a8f007edd534 112 Pfam PF02036 SCP-2 sterol transfer family 9 105 4.7E-16 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS20115 f900446b215999cc1fa9a8f007edd534 112 SUPERFAMILY SSF55718 1 106 1.65E-21 T 29-03-2018 IPR003033 SCP2 sterol-binding domain A616_RS31095 95ed3e9d2087bee821b7f8f369f7c037 231 Pfam PF02308 MgtC family 15 141 1.2E-32 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS31095 95ed3e9d2087bee821b7f8f369f7c037 231 PRINTS PR01837 MgtC/SapB protein signature 37 55 5.7E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS31095 95ed3e9d2087bee821b7f8f369f7c037 231 PRINTS PR01837 MgtC/SapB protein signature 18 37 5.7E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS31095 95ed3e9d2087bee821b7f8f369f7c037 231 PRINTS PR01837 MgtC/SapB protein signature 99 123 5.7E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS31095 95ed3e9d2087bee821b7f8f369f7c037 231 PRINTS PR01837 MgtC/SapB protein signature 71 93 5.7E-41 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A616_RS06900 a39db41360d7f0e5502ace67b6d3f78d 124 Pfam PF04241 Protein of unknown function (DUF423) 18 105 1.8E-31 T 29-03-2018 IPR006696 Protein of unknown function DUF423 A616_RS18710 58dbb990a45a911a6849a1f45e68db52 170 Gene3D G3DSA:3.90.175.10 13 116 2.8E-4 T 29-03-2018 A616_RS10730 7a007169a13c292292ba33b743eb7fe9 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.464 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A616_RS10730 7a007169a13c292292ba33b743eb7fe9 170 SUPERFAMILY SSF53271 2 166 1.99E-46 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like A616_RS10730 7a007169a13c292292ba33b743eb7fe9 170 Gene3D G3DSA:3.40.50.2020 1 169 6.8E-38 T 29-03-2018 A616_RS10730 7a007169a13c292292ba33b743eb7fe9 170 Pfam PF00156 Phosphoribosyl transferase domain 27 148 1.1E-15 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A616_RS10730 7a007169a13c292292ba33b743eb7fe9 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 170 2.3E-66 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A616_RS26220 f1c71237c9e26d5bc95e51576ab4e5e7 198 Pfam PF00174 Oxidoreductase molybdopterin binding domain 31 178 2.7E-35 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS26220 f1c71237c9e26d5bc95e51576ab4e5e7 198 SUPERFAMILY SSF56524 9 197 5.76E-59 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS26220 f1c71237c9e26d5bc95e51576ab4e5e7 198 Gene3D G3DSA:3.90.420.10 4 198 1.1E-52 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS21795 75e7ff4714f570c15723971752d55e09 218 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 12 198 1.9E-45 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT A616_RS28705 e172b00a0bf5ebce017b3c4866e87111 372 Gene3D G3DSA:1.25.40.10 72 349 4.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS16120 fcd19dc209815faf8ec9793c9cd0bcc2 203 Pfam PF14137 Domain of unknown function (DUF4304) 14 125 1.7E-21 T 29-03-2018 IPR025412 Protein of unknown function DUF4304 A616_RS16120 fcd19dc209815faf8ec9793c9cd0bcc2 203 Gene3D G3DSA:1.10.10.440 149 196 0.005 T 29-03-2018 A616_RS16350 f13d2d8b62bc2dc8732531852ce99cbe 406 Gene3D G3DSA:2.30.140.20 303 341 0.002 T 29-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain A616_RS16350 f13d2d8b62bc2dc8732531852ce99cbe 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 6.5E-7 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS16350 f13d2d8b62bc2dc8732531852ce99cbe 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 112 129 6.5E-7 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A616_RS16350 f13d2d8b62bc2dc8732531852ce99cbe 406 SUPERFAMILY SSF56601 5 276 1.39E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS16350 f13d2d8b62bc2dc8732531852ce99cbe 406 Gene3D G3DSA:3.40.710.10 19 302 1.8E-57 T 29-03-2018 A616_RS16350 f13d2d8b62bc2dc8732531852ce99cbe 406 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 32 256 9.8E-55 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A616_RS23025 e65e5ec28394989f859daa9bfc312b14 177 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.2E-16 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal A616_RS23025 e65e5ec28394989f859daa9bfc312b14 177 Gene3D G3DSA:1.10.10.10 1 90 4.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23025 e65e5ec28394989f859daa9bfc312b14 177 SUPERFAMILY SSF46785 3 165 4.24E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS12205 585186da88ffc9e9390a793ea4268151 227 Pfam PF07136 Protein of unknown function (DUF1385) 76 211 1.7E-9 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 A616_RS10935 d935587bc804e7efa4c0e480f3c60628 136 Gene3D G3DSA:2.60.40.10 28 129 4.1E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold A616_RS10935 d935587bc804e7efa4c0e480f3c60628 136 SUPERFAMILY SSF49265 54 113 6.42E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 A616_RS13255 25c942e192b9e1c0ce4ea69631a920d0 86 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 4 77 2.0E-12 T 29-03-2018 IPR020138 Uncharacterised protein family YqzF A616_RS13255 25c942e192b9e1c0ce4ea69631a920d0 86 Pfam PF11118 Protein of unknown function (DUF2627) 4 77 1.4E-30 T 29-03-2018 IPR020138 Uncharacterised protein family YqzF A616_RS04595 1d8a431311195c14ec3cfebf89b8931f 174 SUPERFAMILY SSF55729 4 172 4.29E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS04595 1d8a431311195c14ec3cfebf89b8931f 174 Gene3D G3DSA:3.40.630.30 2 174 6.5E-22 T 29-03-2018 A616_RS04595 1d8a431311195c14ec3cfebf89b8931f 174 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 6.1E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS15785 2db95adaf36a32407497a79c3c3f8071 204 SUPERFAMILY SSF46785 13 149 3.66E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS15785 2db95adaf36a32407497a79c3c3f8071 204 Pfam PF13463 Winged helix DNA-binding domain 41 108 2.9E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15785 2db95adaf36a32407497a79c3c3f8071 204 SMART SM00347 33 134 4.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A616_RS15785 2db95adaf36a32407497a79c3c3f8071 204 Gene3D G3DSA:1.10.10.10 4 152 4.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS29295 b3d3537a15777d4d4f65edca7f303a05 298 PIRSF PIRSF003097 1 298 1.1E-92 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 A616_RS29295 b3d3537a15777d4d4f65edca7f303a05 298 Pfam PF02687 FtsX-like permease family 200 286 6.3E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS26630 5dad1d74ba0bebc7397b7ae9ac9ca3cb 337 Pfam PF10974 Protein of unknown function (DUF2804) 19 336 3.7E-91 T 29-03-2018 IPR021243 Protein of unknown function DUF2804 A616_RS16430 055a7b276bc969d8f13cb7b7d60780d6 113 Gene3D G3DSA:3.30.420.10 1 109 5.0E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A616_RS26470 1192fe278370e26c2d377f2ff3c608f6 221 Pfam PF06265 Protein of unknown function (DUF1027) 18 99 1.6E-35 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 A616_RS24660 926f602640d4857ad8eaad15e3d2f567 324 Pfam PF01497 Periplasmic binding protein 109 299 3.4E-22 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS24660 926f602640d4857ad8eaad15e3d2f567 324 Gene3D G3DSA:3.40.50.1980 155 324 1.4E-30 T 29-03-2018 A616_RS24660 926f602640d4857ad8eaad15e3d2f567 324 SUPERFAMILY SSF53807 51 318 6.67E-48 T 29-03-2018 A616_RS24660 926f602640d4857ad8eaad15e3d2f567 324 Gene3D G3DSA:3.40.50.1980 36 154 5.0E-17 T 29-03-2018 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 SUPERFAMILY SSF46689 271 318 2.55E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 SMART SM00342 234 317 7.7E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 271 313 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 Pfam PF12833 Helix-turn-helix domain 240 318 3.8E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 Gene3D G3DSA:3.90.1240.10 118 322 1.6E-23 T 29-03-2018 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 301 4.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS08435 a0b942a368ea6cbf606fc3b4b5845763 324 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 317 4.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A616_RS27715 89d4771997209de63dc47560723dc815 191 Gene3D G3DSA:3.40.630.30 2 189 4.1E-31 T 29-03-2018 A616_RS27715 89d4771997209de63dc47560723dc815 191 SUPERFAMILY SSF55729 14 181 7.27E-44 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS27715 89d4771997209de63dc47560723dc815 191 Pfam PF13302 Acetyltransferase (GNAT) domain 19 157 6.6E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS16415 ee695cc9ffd33647588c6e938b1576b3 133 Pfam PF15891 Nucleoside 2-deoxyribosyltransferase like 2 84 4.8E-11 T 29-03-2018 A616_RS25695 1d11d6a1690b05cacd19fa953a173175 362 Pfam PF07786 Protein of unknown function (DUF1624) 7 219 1.2E-14 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 A616_RS25695 1d11d6a1690b05cacd19fa953a173175 362 Pfam PF04235 Protein of unknown function (DUF418) 256 360 8.3E-10 T 29-03-2018 IPR007349 Domain of unknown function DUF418 A616_RS26315 233ec71a5d3da055a6a78f998f96ff6c 305 Gene3D G3DSA:1.10.10.720 8 52 0.0028 T 29-03-2018 A616_RS06310 b4d5237ef97f477b9ce7a75d0bffd2c1 103 Gene3D G3DSA:1.10.10.10 12 88 8.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS05285 5c4ecfaf27f126895f2b64cd39a56f0e 444 Pfam PF05525 Branched-chain amino acid transport protein 6 432 2.5E-158 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A616_RS05285 5c4ecfaf27f126895f2b64cd39a56f0e 444 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 419 3.7E-147 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A616_RS04460 4b15b95a58e48b9633ca9c439145ad2a 202 SUPERFAMILY SSF141571 28 165 1.96E-28 T 29-03-2018 A616_RS04460 4b15b95a58e48b9633ca9c439145ad2a 202 Pfam PF13599 Pentapeptide repeats (9 copies) 50 123 2.2E-9 T 29-03-2018 IPR001646 Pentapeptide repeat A616_RS04460 4b15b95a58e48b9633ca9c439145ad2a 202 Gene3D G3DSA:2.160.10.20 21 105 2.6E-12 T 29-03-2018 A616_RS04460 4b15b95a58e48b9633ca9c439145ad2a 202 Gene3D G3DSA:2.160.10.20 106 179 1.5E-13 T 29-03-2018 A616_RS25700 e41580833c04c2d12ce717d67b2d7246 157 SUPERFAMILY SSF55729 4 149 4.96E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS25700 e41580833c04c2d12ce717d67b2d7246 157 Gene3D G3DSA:3.40.630.30 5 156 6.8E-18 T 29-03-2018 A616_RS25700 e41580833c04c2d12ce717d67b2d7246 157 Pfam PF13508 Acetyltransferase (GNAT) domain 52 134 1.4E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS32075 10bc05678fe2e04621f7e8f755358218 282 Pfam PF10978 Protein of unknown function (DUF2785) 83 253 2.3E-52 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 A616_RS06395 6a28df00ae64be315038c471de137609 445 Pfam PF17482 Phage tail sheath C-terminal domain 349 409 8.8E-8 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain A616_RS06395 6a28df00ae64be315038c471de137609 445 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 184 340 4.2E-10 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain A616_RS06395 6a28df00ae64be315038c471de137609 445 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 333 407 0.005 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain A616_RS30430 0eb37ee0676eccf9404a05e56894df00 201 Pfam PF06177 QueT transporter 17 173 9.6E-9 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 A616_RS07170 99e75271f8a61b4ea1f512c6a2fbba97 172 Hamap MF_01515 UPF0316 protein . 3 171 28.625 T 29-03-2018 IPR022930 Protein of unknown function UPF0316 A616_RS07170 99e75271f8a61b4ea1f512c6a2fbba97 172 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 111 163 2.3E-8 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 A616_RS27210 9452d4b821b1b06b716dc5f446462cc7 117 Pfam PF00072 Response regulator receiver domain 5 113 1.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27210 9452d4b821b1b06b716dc5f446462cc7 117 SMART SM00448 2 113 1.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A616_RS27210 9452d4b821b1b06b716dc5f446462cc7 117 SUPERFAMILY SSF52172 1 117 3.7E-34 T 29-03-2018 IPR011006 CheY-like superfamily A616_RS27210 9452d4b821b1b06b716dc5f446462cc7 117 Gene3D G3DSA:3.40.50.2300 1 117 3.6E-34 T 29-03-2018 A616_RS09875 5fa2ce6b08abc2ac48543db2fd9cbe70 97 Gene3D G3DSA:1.10.340.20 11 95 6.5E-20 T 29-03-2018 A616_RS09875 5fa2ce6b08abc2ac48543db2fd9cbe70 97 Pfam PF08958 Domain of unknown function (DUF1871) 18 94 7.2E-8 T 29-03-2018 IPR015053 Protein of unknown function DUF1871 A616_RS09875 5fa2ce6b08abc2ac48543db2fd9cbe70 97 SUPERFAMILY SSF116922 13 94 6.8E-13 T 29-03-2018 IPR023162 Apc36109-like domain A616_RS14775 bf204a9bbac145367954d18b130fb822 310 SUPERFAMILY SSF161098 89 287 1.26E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14775 bf204a9bbac145367954d18b130fb822 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 6.9E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS14775 bf204a9bbac145367954d18b130fb822 310 Gene3D G3DSA:1.10.3720.10 1 293 1.7E-34 T 29-03-2018 A616_RS13490 bde3cbb542561e2981d1d50642aad0a9 177 Pfam PF07670 Nucleoside recognition 47 147 5.3E-6 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A616_RS16115 a12469ef6205708f121a5b97165b36d1 152 Pfam PF10990 Protein of unknown function (DUF2809) 53 136 1.1E-24 T 29-03-2018 IPR021257 Protein of unknown function DUF2809 A616_RS05775 90610024f024928723a8134a2cb0ffff 149 Pfam PF02627 Carboxymuconolactone decarboxylase family 13 94 2.3E-22 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A616_RS05775 90610024f024928723a8134a2cb0ffff 149 SUPERFAMILY SSF69118 5 143 7.46E-47 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A616_RS05775 90610024f024928723a8134a2cb0ffff 149 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 78 4.1E-20 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A616_RS05775 90610024f024928723a8134a2cb0ffff 149 Gene3D G3DSA:1.20.1290.10 2 148 8.3E-40 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A616_RS01835 acfb07d7acf74aacd129dfe21b7214c3 169 Pfam PF03929 PepSY-associated TM region 4 157 2.6E-11 T 29-03-2018 IPR005625 PepSY-associated TM protein A616_RS19810 6f7f2f9d0a923a6be5c366d4a762c7ae 96 Gene3D G3DSA:3.30.1230.10 1 96 7.1E-30 T 29-03-2018 IPR007393 Domain of unknown function DUF448 A616_RS19810 6f7f2f9d0a923a6be5c366d4a762c7ae 96 Pfam PF04296 Protein of unknown function (DUF448) 9 87 2.7E-26 T 29-03-2018 IPR007393 Domain of unknown function DUF448 A616_RS19810 6f7f2f9d0a923a6be5c366d4a762c7ae 96 SUPERFAMILY SSF64376 4 89 2.62E-23 T 29-03-2018 IPR007393 Domain of unknown function DUF448 A616_RS27345 d1750dc8515f2a5de4bee477fb279471 300 Gene3D G3DSA:2.60.40.1220 185 274 0.015 T 29-03-2018 A616_RS27345 d1750dc8515f2a5de4bee477fb279471 300 Pfam PF13205 Bacterial Ig-like domain 181 280 5.3E-14 T 29-03-2018 IPR032812 SbsA, Ig-like domain A616_RS27345 d1750dc8515f2a5de4bee477fb279471 300 Pfam PF13205 Bacterial Ig-like domain 78 178 9.4E-11 T 29-03-2018 IPR032812 SbsA, Ig-like domain A616_RS00965 bf4fbf019d29d38693522f5945290712 302 Pfam PF00482 Type II secretion system (T2SS), protein F 166 291 6.1E-11 T 29-03-2018 IPR018076 Type II secretion system F domain A616_RS23825 24c8afef7f45facb6c5702ed688eae62 256 SUPERFAMILY SSF81593 131 256 1.88E-55 T 29-03-2018 A616_RS23825 24c8afef7f45facb6c5702ed688eae62 256 SUPERFAMILY SSF81301 5 126 4.91E-17 T 29-03-2018 A616_RS23825 24c8afef7f45facb6c5702ed688eae62 256 Gene3D G3DSA:1.20.120.330 133 254 3.2E-51 T 29-03-2018 A616_RS23825 24c8afef7f45facb6c5702ed688eae62 256 Gene3D G3DSA:3.30.460.10 3 129 3.2E-18 T 29-03-2018 A616_RS23825 24c8afef7f45facb6c5702ed688eae62 256 Pfam PF07827 KNTase C-terminal domain 117 248 1.3E-61 T 29-03-2018 IPR012481 Kanamycin nucleotidyltransferase, C-terminal GO:0016779|GO:0046677 A616_RS22460 dca0f0ac6fede785b6550176877ebef4 315 Gene3D G3DSA:1.10.3210.10 105 308 2.7E-11 T 29-03-2018 A616_RS22460 dca0f0ac6fede785b6550176877ebef4 315 SUPERFAMILY SSF50249 6 85 9.85E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold A616_RS22460 dca0f0ac6fede785b6550176877ebef4 315 SUPERFAMILY SSF109604 139 281 6.91E-11 T 29-03-2018 A616_RS22460 dca0f0ac6fede785b6550176877ebef4 315 Gene3D G3DSA:2.40.50.140 3 103 5.9E-11 T 29-03-2018 A616_RS22460 dca0f0ac6fede785b6550176877ebef4 315 Pfam PF01966 HD domain 162 258 1.9E-6 T 29-03-2018 IPR006674 HD domain A616_RS14590 24c1816428211052058b081ff70d5e55 409 SUPERFAMILY SSF103473 6 251 5.1E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS14590 24c1816428211052058b081ff70d5e55 409 SUPERFAMILY SSF103473 251 387 2.88E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS14590 24c1816428211052058b081ff70d5e55 409 Gene3D G3DSA:1.20.1250.20 1 196 9.9E-33 T 29-03-2018 A616_RS14590 24c1816428211052058b081ff70d5e55 409 PRINTS PR01035 Tetracycline resistance protein signature 48 67 1.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14590 24c1816428211052058b081ff70d5e55 409 PRINTS PR01035 Tetracycline resistance protein signature 339 362 1.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14590 24c1816428211052058b081ff70d5e55 409 PRINTS PR01035 Tetracycline resistance protein signature 106 127 1.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14590 24c1816428211052058b081ff70d5e55 409 PRINTS PR01035 Tetracycline resistance protein signature 278 299 1.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14590 24c1816428211052058b081ff70d5e55 409 PRINTS PR01035 Tetracycline resistance protein signature 18 34 1.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14590 24c1816428211052058b081ff70d5e55 409 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A616_RS14590 24c1816428211052058b081ff70d5e55 409 Gene3D G3DSA:1.20.1250.20 197 405 1.3E-28 T 29-03-2018 A616_RS14590 24c1816428211052058b081ff70d5e55 409 Pfam PF07690 Major Facilitator Superfamily 12 259 5.8E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS20500 1816432283a0781c8219ddf4affb24cf 359 Pfam PF09992 Phosphodiester glycosidase 182 357 2.0E-38 T 29-03-2018 IPR018711 Phosphodiester glycosidase A616_RS31575 2e47be56b5a553dc117f063b2f6db3b1 260 SUPERFAMILY SSF56784 13 247 5.95E-38 T 29-03-2018 IPR023214 HAD-like domain A616_RS31575 2e47be56b5a553dc117f063b2f6db3b1 260 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 108 222 6.4E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS31575 2e47be56b5a553dc117f063b2f6db3b1 260 Gene3D G3DSA:3.40.50.1000 5 258 2.0E-34 T 29-03-2018 IPR023214 HAD-like domain A616_RS31575 2e47be56b5a553dc117f063b2f6db3b1 260 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 142 219 1.7E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A616_RS31575 2e47be56b5a553dc117f063b2f6db3b1 260 Pfam PF13419 Haloacid dehalogenase-like hydrolase 113 222 5.1E-24 T 29-03-2018 IPR023214 HAD-like domain A616_RS14265 c5c447ffa6d00281bf8f93c9685b3ef6 223 SUPERFAMILY SSF55729 18 149 2.9E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS14265 c5c447ffa6d00281bf8f93c9685b3ef6 223 Gene3D G3DSA:3.40.630.30 12 223 1.2E-23 T 29-03-2018 A616_RS14265 c5c447ffa6d00281bf8f93c9685b3ef6 223 Pfam PF00583 Acetyltransferase (GNAT) family 29 148 2.7E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS17830 6103a2287b0c0261be4054072f1ade33 160 Gene3D G3DSA:3.40.630.30 6 160 7.7E-23 T 29-03-2018 A616_RS17830 6103a2287b0c0261be4054072f1ade33 160 SUPERFAMILY SSF55729 13 145 6.42E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS17830 6103a2287b0c0261be4054072f1ade33 160 Pfam PF13508 Acetyltransferase (GNAT) domain 54 136 5.1E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS25285 6ac7252b86e8689a17091877a8fe4655 98 Pfam PF01475 Ferric uptake regulator family 16 86 7.0E-17 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A616_RS25285 6ac7252b86e8689a17091877a8fe4655 98 SUPERFAMILY SSF46785 8 87 5.35E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS25285 6ac7252b86e8689a17091877a8fe4655 98 Gene3D G3DSA:1.10.10.10 1 87 2.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS17925 78a53be088081173fc02ab428ae85eb7 230 SUPERFAMILY SSF56059 153 211 3.2E-16 T 29-03-2018 A616_RS17925 78a53be088081173fc02ab428ae85eb7 230 SUPERFAMILY SSF56059 14 118 3.2E-16 T 29-03-2018 A616_RS17925 78a53be088081173fc02ab428ae85eb7 230 Pfam PF14398 YheC/D like ATP-grasp 3 226 5.8E-49 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS17925 78a53be088081173fc02ab428ae85eb7 230 Gene3D G3DSA:3.30.470.20 4 221 2.2E-21 T 29-03-2018 A616_RS17475 34821b23b12793b839964f01f5e0eea8 75 Gene3D G3DSA:1.10.260.40 3 75 6.3E-18 T 29-03-2018 A616_RS17475 34821b23b12793b839964f01f5e0eea8 75 Pfam PF01381 Helix-turn-helix 10 64 1.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS17475 34821b23b12793b839964f01f5e0eea8 75 SUPERFAMILY SSF47413 4 70 1.23E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A616_RS17475 34821b23b12793b839964f01f5e0eea8 75 SMART SM00530 9 64 1.3E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A616_RS27605 f204e3e65c11ff24420e55df9221a640 247 Pfam PF00005 ABC transporter 22 164 1.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS27605 f204e3e65c11ff24420e55df9221a640 247 Gene3D G3DSA:3.40.50.300 1 232 3.4E-57 T 29-03-2018 A616_RS27605 f204e3e65c11ff24420e55df9221a640 247 SUPERFAMILY SSF52540 3 225 5.11E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS27605 f204e3e65c11ff24420e55df9221a640 247 SMART SM00382 30 215 2.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS31900 8e8aa2c589704c1c2fe3887cb4863a02 211 Pfam PF06889 Protein of unknown function (DUF1266) 42 181 8.9E-27 T 29-03-2018 IPR009677 Protein of unknown function DUF1266 A616_RS13085 db31d9ce17e727b69372edce639b76b8 224 Pfam PF12685 SpoIIIAH-like protein 6 219 8.9E-44 T 29-03-2018 IPR024232 Stage III sporulation protein AH-like A616_RS16060 46e44c4680830959e62a5f9721a4a501 352 SUPERFAMILY SSF51905 6 206 2.43E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS16060 46e44c4680830959e62a5f9721a4a501 352 SUPERFAMILY SSF51905 292 348 2.43E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS16060 46e44c4680830959e62a5f9721a4a501 352 Gene3D G3DSA:3.50.50.60 2 350 1.2E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS16060 46e44c4680830959e62a5f9721a4a501 352 Pfam PF01266 FAD dependent oxidoreductase 6 328 3.9E-39 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A616_RS11875 93f1dabba1060d41598dce3cbfaec26f 392 Pfam PF12698 ABC-2 family transporter protein 25 372 1.9E-36 T 29-03-2018 A616_RS11875 93f1dabba1060d41598dce3cbfaec26f 392 Gene3D G3DSA:3.40.1710.10 41 200 3.3E-25 T 29-03-2018 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 SUPERFAMILY SSF48371 120 165 6.12E-20 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 SUPERFAMILY SSF48371 197 321 6.12E-20 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 SMART SM00567 E-Z type HEAT repeats 276 305 0.82 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 SMART SM00567 E-Z type HEAT repeats 120 149 32.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 SMART SM00567 E-Z type HEAT repeats 307 335 140.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 Pfam PF13646 HEAT repeats 270 338 1.3E-9 T 29-03-2018 A616_RS07810 c64f93b3b63740b372c03b7ed9f6f460 394 Gene3D G3DSA:1.25.10.10 118 343 3.1E-17 T 29-03-2018 IPR011989 Armadillo-like helical A616_RS16275 a94d15ee7f0653976a5c401c67a41e5c 121 SUPERFAMILY SSF103481 2 97 2.48E-13 T 29-03-2018 A616_RS16275 a94d15ee7f0653976a5c401c67a41e5c 121 Pfam PF00893 Small Multidrug Resistance protein 2 86 3.4E-18 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 A616_RS29080 5a2e9d0bf138fd9d93197e00712363e5 338 SUPERFAMILY SSF81345 6 334 4.97E-74 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS29080 5a2e9d0bf138fd9d93197e00712363e5 338 Gene3D G3DSA:1.10.3470.10 6 338 1.1E-59 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS29080 5a2e9d0bf138fd9d93197e00712363e5 338 Pfam PF01032 FecCD transport family 22 334 4.6E-84 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS11240 dbbdb5c88b0ac2dfc841c9fa8527c8dc 249 Pfam PF13649 Methyltransferase domain 39 133 1.1E-21 T 29-03-2018 A616_RS11240 dbbdb5c88b0ac2dfc841c9fa8527c8dc 249 Gene3D G3DSA:2.20.25.110 141 203 1.4E-22 T 29-03-2018 A616_RS11240 dbbdb5c88b0ac2dfc841c9fa8527c8dc 249 Gene3D G3DSA:3.40.50.150 2 136 1.1E-25 T 29-03-2018 A616_RS11240 dbbdb5c88b0ac2dfc841c9fa8527c8dc 249 SUPERFAMILY SSF53335 3 245 9.8E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS15965 76b53998f2bd4821475df62f8c898485 116 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 3 113 2.5E-33 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 A616_RS28180 e0610b4e02ec3eeec59cd85ef750825a 466 Pfam PF00939 Sodium:sulfate symporter transmembrane region 17 463 1.4E-35 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A616_RS22250 943b8dcc6c587bcb9fd6e8aa3c7fe785 226 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 185 4.9E-67 T 29-03-2018 IPR022301 Integral membrane protein YjbE A616_RS22250 943b8dcc6c587bcb9fd6e8aa3c7fe785 226 Pfam PF03741 Integral membrane protein TerC family 16 184 7.9E-44 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 A616_RS06775 9b13abc91195278156ef462749bb5a8c 126 Gene3D G3DSA:2.60.120.380 17 125 7.4E-12 T 29-03-2018 A616_RS06775 9b13abc91195278156ef462749bb5a8c 126 SUPERFAMILY SSF89260 23 123 2.75E-8 T 29-03-2018 A616_RS02535 628c7a1c64a8f427033c4f382f5d5745 342 Gene3D G3DSA:3.20.20.70 1 341 5.7E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS02535 628c7a1c64a8f427033c4f382f5d5745 342 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 323 2.7E-71 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A616_RS02535 628c7a1c64a8f427033c4f382f5d5745 342 SUPERFAMILY SSF51395 1 339 2.63E-108 T 29-03-2018 A616_RS13750 15cea54da716078c91337f34d042619d 278 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 25 192 2.6E-41 T 29-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 A616_RS13750 15cea54da716078c91337f34d042619d 278 Gene3D G3DSA:1.10.600.10 1 268 1.3E-4 T 29-03-2018 IPR008949 Isoprenoid synthase domain A616_RS21165 1ec3076c9852f251e644a07b8c277568 198 SUPERFAMILY SSF49764 89 191 2.48E-18 T 29-03-2018 IPR008978 HSP20-like chaperone A616_RS21165 1ec3076c9852f251e644a07b8c277568 198 Gene3D G3DSA:2.60.40.790 1 193 2.4E-21 T 29-03-2018 IPR008978 HSP20-like chaperone A616_RS21165 1ec3076c9852f251e644a07b8c277568 198 Pfam PF00011 Hsp20/alpha crystallin family 96 187 4.4E-12 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain A616_RS15940 d9f028178c67af68da5e87d4318c2f4b 141 Gene3D G3DSA:3.10.180.10 1 138 1.1E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS15940 d9f028178c67af68da5e87d4318c2f4b 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 112 3.2E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS15940 d9f028178c67af68da5e87d4318c2f4b 141 SUPERFAMILY SSF54593 1 119 1.33E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 Gene3D G3DSA:3.40.190.10 90 179 2.4E-23 T 29-03-2018 A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 SUPERFAMILY SSF46785 1 83 2.01E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 SUPERFAMILY SSF53850 88 290 1.18E-43 T 29-03-2018 A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 Pfam PF03466 LysR substrate binding domain 89 289 7.1E-48 T 29-03-2018 IPR005119 LysR, substrate-binding A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 Gene3D G3DSA:1.10.10.10 1 83 2.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS09235 ff9edc2076d5e0d748f3cedaaf198c45 294 Gene3D G3DSA:3.40.190.10 180 264 2.0E-22 T 29-03-2018 A616_RS30445 83b48f84ad17e9a50b9156253f3b3dc5 444 PIRSF PIRSF006060 2 442 3.0E-73 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS30445 83b48f84ad17e9a50b9156253f3b3dc5 444 Pfam PF00324 Amino acid permease 15 400 2.2E-34 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 A616_RS16385 0ac3581508980843bc809f89b2309bd3 572 SUPERFAMILY SSF53300 389 535 5.19E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS16385 0ac3581508980843bc809f89b2309bd3 572 Gene3D G3DSA:3.40.50.410 374 558 6.7E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A A616_RS27020 fdd3af5e4cf286927cecd98c9fed6b74 106 Gene3D G3DSA:1.20.1260.10 17 106 1.2E-10 T 29-03-2018 IPR012347 Ferritin-related A616_RS27020 fdd3af5e4cf286927cecd98c9fed6b74 106 SUPERFAMILY SSF47240 26 85 1.23E-6 T 29-03-2018 IPR009078 Ferritin-like superfamily A616_RS07335 07482da4cc4b123ad3ccf2467376b1fb 216 SUPERFAMILY SSF63965 9 212 2.88E-72 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 A616_RS07335 07482da4cc4b123ad3ccf2467376b1fb 216 Gene3D G3DSA:3.40.50.10230 10 215 1.4E-83 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 A616_RS07335 07482da4cc4b123ad3ccf2467376b1fb 216 Pfam PF02570 Precorrin-8X methylmutase 16 209 6.5E-78 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 A616_RS11880 a3387ef87b9d3fe26c01619ac4073e5c 170 Pfam PF13047 Protein of unknown function (DUF3907) 10 158 4.5E-60 T 29-03-2018 IPR025013 Protein of unknown function DUF3907 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 SUPERFAMILY SSF51905 4 170 1.9E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 SUPERFAMILY SSF51905 260 366 1.9E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 304 8.2E-40 T 29-03-2018 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 324 8.2E-40 T 29-03-2018 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 340 8.2E-40 T 29-03-2018 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.2E-40 T 29-03-2018 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 8.2E-40 T 29-03-2018 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 8.2E-40 T 29-03-2018 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 Pfam PF01494 FAD binding domain 5 338 2.1E-89 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 A616_RS12235 fba40c77971ae7c2b45ed61d2f2775e2 503 Gene3D G3DSA:3.50.50.60 2 386 1.0E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A616_RS07015 bc116fbe45b9af73be7eb3b70be67e3a 344 PIRSF PIRSF017082 5 344 2.8E-102 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A616_RS07015 bc116fbe45b9af73be7eb3b70be67e3a 344 SUPERFAMILY SSF53850 116 303 6.08E-10 T 29-03-2018 A616_RS07015 bc116fbe45b9af73be7eb3b70be67e3a 344 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 337 9.5E-36 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A616_RS07015 bc116fbe45b9af73be7eb3b70be67e3a 344 Gene3D G3DSA:3.40.190.10 141 276 9.1E-15 T 29-03-2018 A616_RS21520 3dee141631ff92b6336ff79ca7601428 108 Pfam PF14036 YlaH-like protein 26 100 1.1E-19 T 29-03-2018 IPR025620 YlaH-like protein A616_RS05255 b12c96f42511322296a7912449ec03dd 372 Gene3D G3DSA:2.120.10.30 270 367 6.5E-15 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS05255 b12c96f42511322296a7912449ec03dd 372 Gene3D G3DSA:2.120.10.30 22 269 8.4E-56 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A616_RS05255 b12c96f42511322296a7912449ec03dd 372 Pfam PF07995 Glucose / Sorbosone dehydrogenase 48 354 2.1E-90 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase A616_RS05255 b12c96f42511322296a7912449ec03dd 372 SUPERFAMILY SSF50952 32 354 5.23E-41 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 A616_RS21975 c2fc7f3de5265472a4845f806d0c0848 207 SUPERFAMILY SSF52540 15 181 3.55E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS21975 c2fc7f3de5265472a4845f806d0c0848 207 Gene3D G3DSA:3.40.50.300 4 191 6.2E-19 T 29-03-2018 A616_RS21975 c2fc7f3de5265472a4845f806d0c0848 207 Pfam PF13671 AAA domain 17 139 1.5E-10 T 29-03-2018 A616_RS28885 25a6a71ecb268cf0676a869aff9925c6 81 SUPERFAMILY SSF47336 4 74 1.28E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28885 25a6a71ecb268cf0676a869aff9925c6 81 Pfam PF00550 Phosphopantetheine attachment site 28 59 2.2E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain A616_RS28885 25a6a71ecb268cf0676a869aff9925c6 81 Gene3D G3DSA:1.10.1200.10 1 80 5.9E-12 T 29-03-2018 A616_RS26650 9474b204722ae348006178cd57521325 274 Pfam PF01925 Sulfite exporter TauE/SafE 10 267 6.4E-52 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A616_RS32025 b370ab37c2f8354636fcc591d7ba8782 222 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 158 211 2.1E-12 T 29-03-2018 A616_RS19005 973b1dde607ed4b0e884b659ad4b6de6 53 Pfam PF09388 Spo0E like sporulation regulatory protein 6 44 5.8E-12 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 A616_RS19005 973b1dde607ed4b0e884b659ad4b6de6 53 SUPERFAMILY SSF140500 6 49 2.49E-8 T 29-03-2018 A616_RS21155 844941afe5df70ba7813a919d19360ad 71 Pfam PF10676 Spore germination protein gerPA/gerPF 2 70 3.9E-23 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF A616_RS19990 e9db27aa506f4bd1c7d728d3ba863a21 151 Pfam PF03748 Flagellar basal body-associated protein FliL 60 147 6.5E-12 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 A616_RS10385 9a471ef15a88cb45da260d872f95d440 183 Pfam PF08006 Protein of unknown function (DUF1700) 1 182 4.7E-50 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 A616_RS09590 3c031da123d57fd4154c3edee951435d 91 Pfam PF05164 Cell division protein ZapA 10 82 3.1E-16 T 29-03-2018 IPR007838 Cell division protein ZapA-like A616_RS09590 3c031da123d57fd4154c3edee951435d 91 SUPERFAMILY SSF102829 9 83 3.53E-17 T 29-03-2018 IPR007838 Cell division protein ZapA-like A616_RS10060 99d3e10ec08c2f4e418ca85a5d1957b3 282 Gene3D G3DSA:3.40.50.150 2 218 3.9E-12 T 29-03-2018 A616_RS10060 99d3e10ec08c2f4e418ca85a5d1957b3 282 SUPERFAMILY SSF53335 17 229 1.7E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A616_RS10060 99d3e10ec08c2f4e418ca85a5d1957b3 282 Pfam PF08003 Protein of unknown function (DUF1698) 51 225 2.5E-11 T 29-03-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like A616_RS16880 b9217717826e96c27267cd36a182c2a2 122 Pfam PF14076 Domain of unknown function (DUF4258) 5 65 8.2E-10 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 A616_RS08375 47afd75b5aead794509f6f15e8209c7a 398 Pfam PF04235 Protein of unknown function (DUF418) 229 381 6.2E-44 T 29-03-2018 IPR007349 Domain of unknown function DUF418 A616_RS04875 78f519be36cbf61174b2d0d03e5af833 237 SUPERFAMILY SSF53474 3 232 1.09E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS04875 78f519be36cbf61174b2d0d03e5af833 237 Gene3D G3DSA:3.40.50.1820 2 236 1.1E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS04875 78f519be36cbf61174b2d0d03e5af833 237 Pfam PF12697 Alpha/beta hydrolase family 4 229 3.7E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A616_RS21450 da9ee2cf74cb2d4b46bf230bb39a0a2a 418 Gene3D G3DSA:3.60.21.10 65 398 5.6E-55 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS21450 da9ee2cf74cb2d4b46bf230bb39a0a2a 418 SMART SM00854 70 322 6.6E-87 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS21450 da9ee2cf74cb2d4b46bf230bb39a0a2a 418 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 71 322 5.0E-72 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA A616_RS21450 da9ee2cf74cb2d4b46bf230bb39a0a2a 418 SUPERFAMILY SSF56300 69 357 2.8E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like A616_RS03250 3039748c93559f5356844e4334d3b345 628 PIRSF PIRSF018968 1 626 9.7E-135 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 A616_RS03250 3039748c93559f5356844e4334d3b345 628 Pfam PF02687 FtsX-like permease family 85 176 4.7E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS20740 f9ce3642cd71d914cd90aa2d3afeeb5f 140 Pfam PF06271 RDD family 12 132 6.7E-21 T 29-03-2018 IPR010432 RDD A616_RS21140 cec47aefb819554e2b8ec98a8f4b497a 204 Pfam PF10737 Spore germination protein GerPC 25 198 2.0E-60 T 29-03-2018 IPR019673 Spore germination protein GerPC A616_RS12230 6a07cfd12de7c2dd07bfb6303f8dead6 778 Pfam PF00395 S-layer homology domain 103 144 1.6E-12 T 29-03-2018 IPR001119 S-layer homology domain A616_RS12230 6a07cfd12de7c2dd07bfb6303f8dead6 778 Pfam PF00395 S-layer homology domain 38 80 3.1E-13 T 29-03-2018 IPR001119 S-layer homology domain A616_RS04795 b619b28e2e8795d02dce9bd5513e6dd2 196 SUPERFAMILY SSF55729 35 179 1.39E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS04795 b619b28e2e8795d02dce9bd5513e6dd2 196 Gene3D G3DSA:3.40.630.30 24 180 2.9E-23 T 29-03-2018 A616_RS04795 b619b28e2e8795d02dce9bd5513e6dd2 196 Pfam PF00583 Acetyltransferase (GNAT) family 68 157 3.8E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS08395 ade8ecffab10b404951ccd2b2cdb67be 460 Pfam PF01963 TraB family 187 458 3.2E-56 T 29-03-2018 IPR002816 Pheromone shutdown, TraB A616_RS13590 81ebb0f4f570b1987d01bd67ec339839 247 SUPERFAMILY SSF102588 3 246 1.7E-44 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS13590 81ebb0f4f570b1987d01bd67ec339839 247 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 137 5.5E-29 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 A616_RS13590 81ebb0f4f570b1987d01bd67ec339839 247 Gene3D G3DSA:3.40.50.10320 1 247 4.6E-46 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 A616_RS05790 17c093d7d3fd1188829ec5ae09b58df9 96 Pfam PF05977 Transmembrane secretion effector 2 61 4.5E-5 T 29-03-2018 IPR010290 Transmembrane secretion effector A616_RS26025 c326f9069f5c9a04e53e10138036b641 113 Pfam PF13564 DoxX-like family 7 106 7.5E-21 T 29-03-2018 IPR032808 DoxX family A616_RS32215 519213eb30ef0238b01fe88e185e7446 69 PIRSF PIRSF037263 1 66 4.2E-34 T 29-03-2018 IPR009296 Protein of unknown function DUF951 A616_RS32215 519213eb30ef0238b01fe88e185e7446 69 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 59 1.3E-29 T 29-03-2018 IPR009296 Protein of unknown function DUF951 A616_RS25040 f0efd543c21b3ab4d9493fbbb474e24c 183 Pfam PF08719 Domain of unknown function (DUF1768) 23 182 6.4E-56 T 29-03-2018 IPR012816 NADAR A616_RS25040 f0efd543c21b3ab4d9493fbbb474e24c 183 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 22 182 1.5E-52 T 29-03-2018 IPR012816 NADAR A616_RS25040 f0efd543c21b3ab4d9493fbbb474e24c 183 SUPERFAMILY SSF143990 17 182 3.14E-53 T 29-03-2018 A616_RS05500 a991dce9527cc9bd82d3577ff1ee118e 247 Pfam PF05076 Suppressor of fused protein (SUFU) 68 243 1.8E-47 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 A616_RS11680 b91329760ea932a747baa33787f0ab43 278 Pfam PF03618 Kinase/pyrophosphorylase 10 265 4.8E-99 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 A616_RS11680 b91329760ea932a747baa33787f0ab43 278 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 8 270 60.249 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein A616_RS11680 b91329760ea932a747baa33787f0ab43 278 Gene3D G3DSA:3.40.50.300 16 273 4.1E-5 T 29-03-2018 A616_RS05390 a83e86b576d0f1dd7afd4bfcf67465e0 214 Pfam PF10946 Protein of unknown function DUF2625 5 205 1.4E-85 T 29-03-2018 IPR021239 Protein of unknown function DUF2625 A616_RS06215 94862c00f871626473fc0e77a3c639c4 299 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 13 163 1.0E-35 T 29-03-2018 IPR017482 Putative phage-type endonuclease A616_RS06215 94862c00f871626473fc0e77a3c639c4 299 Gene3D G3DSA:3.90.320.10 13 217 2.2E-52 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A616_RS06215 94862c00f871626473fc0e77a3c639c4 299 Pfam PF09588 YqaJ-like viral recombinase domain 16 152 2.6E-34 T 29-03-2018 IPR019080 YqaJ viral recombinase A616_RS06215 94862c00f871626473fc0e77a3c639c4 299 SUPERFAMILY SSF52980 14 196 3.49E-45 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A616_RS06410 1e38e2ad2fd2604cab09e493cad8d5e0 1229 Gene3D G3DSA:1.20.58.130 32 119 3.8E-5 T 29-03-2018 A616_RS06410 1e38e2ad2fd2604cab09e493cad8d5e0 1229 Gene3D G3DSA:1.20.5.1230 678 937 1.1E-8 T 29-03-2018 A616_RS18915 5d9ce32452b5d6271aaca34004792205 207 Pfam PF07486 Cell Wall Hydrolase 108 205 5.8E-30 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A616_RS11300 5f700d4fac52ca01097a930790b7c94c 102 Pfam PF12438 Protein of unknown function (DUF3679) 6 60 1.8E-19 T 29-03-2018 IPR020534 Uncharacterised protein family YqxA A616_RS21535 93adf992bb0906ec5de23536ca3348d7 203 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 20 161 3.4E-15 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A616_RS12610 7d8d6294a25194f55a353a24958e4abb 150 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 4 147 24.446 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 A616_RS12610 7d8d6294a25194f55a353a24958e4abb 150 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 27 145 6.4E-34 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 A616_RS11720 e748cb0cb66f7eb5595154837c7f92c7 666 Gene3D G3DSA:1.25.40.10 233 571 1.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS11720 e748cb0cb66f7eb5595154837c7f92c7 666 Pfam PF00395 S-layer homology domain 31 73 6.6E-7 T 29-03-2018 IPR001119 S-layer homology domain A616_RS27355 323e1b9295b0a2389f2e356d88e4c6aa 473 Pfam PF13520 Amino acid permease 31 437 2.0E-61 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS27355 323e1b9295b0a2389f2e356d88e4c6aa 473 PIRSF PIRSF006060 11 471 3.6E-101 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS10700 c68af2a48b5994b2a792a8946f4a6414 237 Gene3D G3DSA:3.30.240.20 82 151 9.5E-22 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A616_RS10700 c68af2a48b5994b2a792a8946f4a6414 237 Gene3D G3DSA:3.30.240.20 171 234 2.6E-14 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain A616_RS10700 c68af2a48b5994b2a792a8946f4a6414 237 Pfam PF04239 Protein of unknown function (DUF421) 89 211 7.9E-34 T 29-03-2018 IPR007353 Protein of unknown function DUF421 A616_RS30625 c5620730e55fd5376ca8099be9338c81 324 SUPERFAMILY SSF53807 45 309 2.33E-54 T 29-03-2018 A616_RS30625 c5620730e55fd5376ca8099be9338c81 324 Gene3D G3DSA:3.40.50.1980 155 323 1.6E-31 T 29-03-2018 A616_RS30625 c5620730e55fd5376ca8099be9338c81 324 Gene3D G3DSA:3.40.50.1980 31 154 1.4E-24 T 29-03-2018 A616_RS30625 c5620730e55fd5376ca8099be9338c81 324 Pfam PF01497 Periplasmic binding protein 84 296 1.6E-26 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A616_RS30415 a2a803c475463d05d62f92d425cd7737 262 Pfam PF02361 Cobalt transport protein 6 215 3.3E-30 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A616_RS18030 348f70085fb0afc54b360eaafcd83ea4 102 Pfam PF00085 Thioredoxin 4 83 2.1E-10 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 A616_RS18030 348f70085fb0afc54b360eaafcd83ea4 102 Gene3D G3DSA:3.40.30.10 1 100 2.5E-13 T 29-03-2018 A616_RS18030 348f70085fb0afc54b360eaafcd83ea4 102 SUPERFAMILY SSF52833 2 99 9.6E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS00585 087430f6e7c54217f08aa4c4856638e9 271 Pfam PF04468 PSP1 C-terminal conserved region 61 146 3.6E-33 T 29-03-2018 IPR007557 PSP1, C-terminal A616_RS31630 7afa39da94a2cb2074a6cfeb3959e566 236 Gene3D G3DSA:3.40.50.150 10 222 1.1E-9 T 29-03-2018 A616_RS07855 3ed276f039d703308e32eb7df24a14da 168 Gene3D G3DSA:1.10.357.10 17 163 7.5E-4 T 29-03-2018 A616_RS24750 325d42e17a970a98d6b653ee36b1ecda 372 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 15 351 1.6E-76 T 29-03-2018 IPR010640 Low temperature requirement A A616_RS10955 48be30c6d6739297c0a9fe14b7eb6369 61 Gene3D G3DSA:1.20.5.100 26 52 2.0E-4 T 29-03-2018 A616_RS03645 26cd42ce25d4aeb37fdc6a011081225a 427 Pfam PF02653 Branched-chain amino acid transport system / permease component 81 381 6.3E-49 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS03645 26cd42ce25d4aeb37fdc6a011081225a 427 Gene3D G3DSA:1.10.3470.10 11 387 1.7E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS03780 8acb0fcc592561ff75363e79955b7966 1085 Gene3D G3DSA:1.20.5.340 416 505 3.5E-4 T 29-03-2018 A616_RS32225 ec45f815569662bc4f52df9baffc4271 93 Pfam PF11823 Protein of unknown function (DUF3343) 7 72 3.0E-17 T 29-03-2018 IPR021778 Domain of unknown function DUF3343 A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 Gene3D G3DSA:2.60.40.50 10 75 7.7E-39 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 28 44 2.8E-27 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 11 28 2.8E-27 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 60 76 2.8E-27 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 44 60 2.8E-27 T 29-03-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 SUPERFAMILY SSF51219 10 75 3.66E-32 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain A616_RS13740 40df60b3e427d78f3e0921a33849207c 76 Pfam PF02081 Tryptophan RNA-binding attenuator protein 8 74 1.2E-38 T 29-03-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain A616_RS20510 46d75afb3e375f33f0e3e55d7d448713 274 Pfam PF06271 RDD family 28 163 5.9E-23 T 29-03-2018 IPR010432 RDD A616_RS22900 2cfe79576ae3c28f14e417108395299f 279 SUPERFAMILY SSF55729 1 114 4.22E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS22900 2cfe79576ae3c28f14e417108395299f 279 Gene3D G3DSA:3.40.630.30 1 142 2.7E-10 T 29-03-2018 A616_RS11165 a4926c0cdf2dd623202427a64198d91f 245 SUPERFAMILY SSF52317 19 238 2.07E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS11165 a4926c0cdf2dd623202427a64198d91f 245 Gene3D G3DSA:3.40.50.880 1 245 2.7E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like A616_RS11165 a4926c0cdf2dd623202427a64198d91f 245 Pfam PF07722 Peptidase C26 3 216 7.3E-60 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A616_RS06545 61e5e4db80db4b165a09031ced8e152a 95 Pfam PF05360 yiaA/B two helix domain 14 67 8.3E-15 T 29-03-2018 IPR008024 YiaAB two helix A616_RS19080 24667d179136b3de917bf1e9782be1b1 161 Pfam PF04306 Protein of unknown function (DUF456) 21 160 5.4E-38 T 29-03-2018 IPR007403 Protein of unknown function DUF456 A616_RS25710 4bcf27156baa4341b270316a026a46e5 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 23 440 1.9E-146 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A616_RS16735 2640381fbec911fb498f40a1b3ea8f3b 339 SUPERFAMILY SSF56731 159 276 1.15E-10 T 29-03-2018 A616_RS16735 2640381fbec911fb498f40a1b3ea8f3b 339 Gene3D G3DSA:3.40.1360.10 207 326 6.6E-4 T 29-03-2018 A616_RS16735 2640381fbec911fb498f40a1b3ea8f3b 339 Gene3D G3DSA:3.90.580.10 15 103 0.0016 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A616_RS30880 9700328333984658f43e8f075acd2f6d 178 Gene3D G3DSA:1.20.120.330 19 147 9.7E-4 T 29-03-2018 A616_RS30615 2d7cfb1bdfac8b7190bb50b22486b602 127 Pfam PF02566 OsmC-like protein 25 120 1.6E-20 T 29-03-2018 IPR003718 OsmC/Ohr family A616_RS30615 2d7cfb1bdfac8b7190bb50b22486b602 127 Gene3D G3DSA:3.30.300.20 1 127 3.1E-26 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta A616_RS30615 2d7cfb1bdfac8b7190bb50b22486b602 127 SUPERFAMILY SSF82784 8 126 1.7E-26 T 29-03-2018 IPR003718 OsmC/Ohr family A616_RS09245 9db0c07f9761120c75764d957fc91136 280 Pfam PF01940 Integral membrane protein DUF92 10 262 1.0E-65 T 29-03-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A616_RS10055 71829dd2e6ae6f0cdc514f72df575b63 395 SUPERFAMILY SSF53448 7 213 2.25E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS10055 71829dd2e6ae6f0cdc514f72df575b63 395 Pfam PF00535 Glycosyl transferase family 2 10 165 6.8E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A616_RS10055 71829dd2e6ae6f0cdc514f72df575b63 395 Gene3D G3DSA:3.90.550.10 7 218 2.8E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS28255 b6c1e2801ec8bad6bce2007600b2d7d3 468 Pfam PF07670 Nucleoside recognition 311 435 5.8E-16 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A616_RS28255 b6c1e2801ec8bad6bce2007600b2d7d3 468 Pfam PF07670 Nucleoside recognition 141 229 3.2E-7 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A616_RS28255 b6c1e2801ec8bad6bce2007600b2d7d3 468 Pfam PF07664 Ferrous iron transport protein B C terminus 253 299 7.7E-13 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A616_RS21030 9efb1fea300757cfe7d1df82ef8a56a5 453 SUPERFAMILY SSF82171 49 409 9.42E-24 T 29-03-2018 A616_RS21030 9efb1fea300757cfe7d1df82ef8a56a5 453 Pfam PF07676 WD40-like Beta Propeller Repeat 83 99 0.0046 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS21030 9efb1fea300757cfe7d1df82ef8a56a5 453 Pfam PF07676 WD40-like Beta Propeller Repeat 379 404 0.042 T 29-03-2018 IPR011659 WD40-like Beta Propeller A616_RS21030 9efb1fea300757cfe7d1df82ef8a56a5 453 Gene3D G3DSA:2.130.10.150 357 443 8.0E-4 T 29-03-2018 A616_RS21030 9efb1fea300757cfe7d1df82ef8a56a5 453 Gene3D G3DSA:2.130.10.150 185 356 1.9E-7 T 29-03-2018 A616_RS21030 9efb1fea300757cfe7d1df82ef8a56a5 453 Gene3D G3DSA:2.130.10.150 46 184 7.2E-14 T 29-03-2018 A616_RS02190 7ef8ed0b2340386a68fdb5b5b347f357 128 Pfam PF07681 DoxX 5 93 1.0E-18 T 29-03-2018 IPR032808 DoxX family A616_RS30480 27c40d3082b7f9288a36a3dcb0dac3dc 275 SUPERFAMILY SSF161098 11 270 1.96E-72 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS30480 27c40d3082b7f9288a36a3dcb0dac3dc 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 269 1.7E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS30480 27c40d3082b7f9288a36a3dcb0dac3dc 275 Gene3D G3DSA:1.10.3720.10 12 271 4.6E-47 T 29-03-2018 A616_RS15800 6a60f273525f090376208a95b0efd97d 189 SUPERFAMILY SSF51182 45 170 1.74E-29 T 29-03-2018 IPR011051 RmlC-like cupin domain A616_RS15800 6a60f273525f090376208a95b0efd97d 189 Gene3D G3DSA:2.60.120.10 64 189 3.6E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold A616_RS15800 6a60f273525f090376208a95b0efd97d 189 Pfam PF07883 Cupin domain 89 164 2.4E-17 T 29-03-2018 IPR013096 Cupin 2, conserved barrel A616_RS22360 fcf7020d72c14e34e786d9f9d993e880 277 Pfam PF08874 Domain of unknown function (DUF1835) 5 127 1.2E-27 T 29-03-2018 IPR014973 Protein of unknown function DUF1835 A616_RS22360 fcf7020d72c14e34e786d9f9d993e880 277 Pfam PF12395 Protein of unknown function 180 271 8.1E-31 T 29-03-2018 IPR022123 Protein of unknown function DUF3658 A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 233 3.8E-42 T 29-03-2018 A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 Gene3D G3DSA:3.40.50.720 1 237 4.6E-53 T 29-03-2018 A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.0E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A616_RS02810 f3ddefc71975bcf2469530bd286095c2 237 SUPERFAMILY SSF51735 4 235 1.32E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS16285 0101c33a66761149ca3397edbeaa538f 118 Pfam PF01638 HxlR-like helix-turn-helix 14 102 2.7E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type A616_RS16285 0101c33a66761149ca3397edbeaa538f 118 SUPERFAMILY SSF46785 3 105 8.19E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS16285 0101c33a66761149ca3397edbeaa538f 118 Gene3D G3DSA:1.10.10.10 12 110 9.6E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS23530 2ecf5e62b720ba933b347108ec71c9f7 145 Pfam PF03994 Domain of Unknown Function (DUF350) 14 78 1.2E-20 T 29-03-2018 IPR007140 Protein of unknown function DUF350 A616_RS23530 2ecf5e62b720ba933b347108ec71c9f7 145 Pfam PF03994 Domain of Unknown Function (DUF350) 90 141 2.3E-13 T 29-03-2018 IPR007140 Protein of unknown function DUF350 A616_RS32110 6f7557195ee4ab9e70f64bb174de8037 257 Pfam PF09648 YycH protein 37 245 4.0E-30 T 29-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 A616_RS27840 204b03e7d2a8ed55075cdec297c3a232 251 Pfam PF14025 Protein of unknown function (DUF4241) 48 233 5.4E-63 T 29-03-2018 IPR025335 Protein of unknown function DUF4241 A616_RS26840 bd92cfcb970b4dff59b3a3836abafa39 233 SUPERFAMILY SSF88713 32 230 4.45E-67 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A616_RS26840 bd92cfcb970b4dff59b3a3836abafa39 233 Gene3D G3DSA:3.20.20.370 21 233 3.3E-63 T 29-03-2018 A616_RS26840 bd92cfcb970b4dff59b3a3836abafa39 233 Pfam PF01522 Polysaccharide deacetylase 38 159 9.6E-33 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A616_RS21250 499936cb92deee10f678b857308fb78c 317 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 305 5.0E-84 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A616_RS21250 499936cb92deee10f678b857308fb78c 317 Pfam PF03419 Sporulation factor SpoIIGA 2 304 2.9E-85 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A616_RS21250 499936cb92deee10f678b857308fb78c 317 PIRSF PIRSF018571 1 307 5.0E-78 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 A616_RS10325 b2f4221da1702b04001a013a180191d0 308 Pfam PF00892 EamA-like transporter family 2 137 5.6E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS10325 b2f4221da1702b04001a013a180191d0 308 Pfam PF00892 EamA-like transporter family 146 284 7.5E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS10325 b2f4221da1702b04001a013a180191d0 308 SUPERFAMILY SSF103481 210 287 2.09E-11 T 29-03-2018 A616_RS10325 b2f4221da1702b04001a013a180191d0 308 SUPERFAMILY SSF103481 36 140 8.11E-13 T 29-03-2018 A616_RS21150 413ed9034fa7711276be9aaac149b548 130 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 6 117 6.0E-13 T 29-03-2018 IPR024496 Spore germination protein GerPE A616_RS21150 413ed9034fa7711276be9aaac149b548 130 Pfam PF10970 Spore germination protein GerPE 5 125 1.7E-30 T 29-03-2018 IPR024496 Spore germination protein GerPE A616_RS29530 e49060db2e7711c59cafc42513387d0d 182 Gene3D G3DSA:2.160.10.10 7 182 4.5E-30 T 29-03-2018 A616_RS29530 e49060db2e7711c59cafc42513387d0d 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 127 159 1.1E-7 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29530 e49060db2e7711c59cafc42513387d0d 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 82 117 6.8E-4 T 29-03-2018 IPR001451 Hexapeptide repeat A616_RS29530 e49060db2e7711c59cafc42513387d0d 182 PIRSF PIRSF000441 17 182 3.7E-46 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A616_RS29530 e49060db2e7711c59cafc42513387d0d 182 SUPERFAMILY SSF51161 63 177 1.94E-35 T 29-03-2018 IPR011004 Trimeric LpxA-like A616_RS04935 c81daf7b9e2aa08e21473ef73a1cec94 129 Pfam PF03788 LrgA family 19 110 5.0E-25 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 A616_RS29850 b33abf853f3f69caadab5b2b3afbae4e 103 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 98 9.3E-26 T 29-03-2018 A616_RS29850 b33abf853f3f69caadab5b2b3afbae4e 103 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 103 20.198 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 A616_RS13915 6cda6556e67a0a83949b764472e865b8 115 Gene3D G3DSA:1.10.3420.10 1 111 5.3E-31 T 29-03-2018 A616_RS13915 6cda6556e67a0a83949b764472e865b8 115 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 105 4.6E-22 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A616_RS13915 6cda6556e67a0a83949b764472e865b8 115 PIRSF PIRSF029904 2 112 1.3E-54 T 29-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A616_RS13915 6cda6556e67a0a83949b764472e865b8 115 SUPERFAMILY SSF101386 5 105 2.47E-29 T 29-03-2018 A616_RS24930 9c040504ff1a22c54ba19dc9ba228425 126 Gene3D G3DSA:3.30.1330.40 1 126 1.2E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS24930 9c040504ff1a22c54ba19dc9ba228425 126 SUPERFAMILY SSF55298 2 126 1.29E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A616_RS24930 9c040504ff1a22c54ba19dc9ba228425 126 Pfam PF01042 Endoribonuclease L-PSP 13 125 1.2E-25 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family A616_RS07720 fbd0ee2d8be51bc8f030f90dc3450c8f 152 Pfam PF03073 TspO/MBR family 11 147 1.9E-25 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 A616_RS20890 68c93a43fa9488cf9bc7432e8a53bf1a 226 Pfam PF02517 CAAX protease self-immunity 119 215 4.9E-12 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A616_RS05785 d1e4760412fb539e9faf66b52f833b67 329 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 169 8.6E-25 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A616_RS24200 d4a10aa74a21da904e0295c282e9bceb 655 Pfam PF00350 Dynamin family 49 274 4.0E-38 T 29-03-2018 IPR022812 Dynamin superfamily A616_RS24200 d4a10aa74a21da904e0295c282e9bceb 655 SUPERFAMILY SSF52540 165 313 9.35E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24200 d4a10aa74a21da904e0295c282e9bceb 655 SUPERFAMILY SSF52540 37 99 9.35E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS24200 d4a10aa74a21da904e0295c282e9bceb 655 Gene3D G3DSA:3.40.50.300 48 587 1.7E-39 T 29-03-2018 A616_RS25415 bff1db2814908f16cd49f336f84f7d3b 471 PIRSF PIRSF006446 1 466 9.1E-179 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A616_RS25415 bff1db2814908f16cd49f336f84f7d3b 471 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 444 1.0E-172 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A616_RS08705 b0322eefd8c44a13815d4945b03e25fb 237 Pfam PF14329 Domain of unknown function (DUF4386) 17 232 3.1E-47 T 29-03-2018 IPR025495 Protein of unknown function DUF4386 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 152 171 9.6E-22 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 107 119 9.6E-22 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 31 47 9.6E-22 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 15 185 4.0E-41 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 ProSitePatterns PS00761 Signal peptidases I signature 3. 157 170 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 SUPERFAMILY SSF51306 30 186 8.5E-44 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 Gene3D G3DSA:2.10.109.10 27 187 3.1E-39 T 29-03-2018 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 Pfam PF00717 Peptidase S24-like 37 126 4.1E-10 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 ProSitePatterns PS00760 Signal peptidases I lysine active site. 109 121 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A616_RS25390 78257b9c75f9d75cd755e9cbcf7eca47 187 ProSitePatterns PS00501 Signal peptidases I serine active site. 40 47 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A616_RS07560 2d29de4bd67e3ec0ab667f668f7088f2 430 Pfam PF00860 Permease family 21 388 1.1E-34 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS14460 eccea27a8494afea6708fe4fe5dfa0ec 320 Gene3D G3DSA:3.40.50.720 1 312 3.9E-36 T 29-03-2018 A616_RS14460 eccea27a8494afea6708fe4fe5dfa0ec 320 SUPERFAMILY SSF51735 1 314 4.03E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain A616_RS14460 eccea27a8494afea6708fe4fe5dfa0ec 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 1.4E-25 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A616_RS30600 81266415d87ef64f0daa218fe146ce13 254 Pfam PF02274 Amidinotransferase 30 251 7.1E-15 T 29-03-2018 A616_RS30600 81266415d87ef64f0daa218fe146ce13 254 Gene3D G3DSA:3.75.10.10 1 254 9.5E-51 T 29-03-2018 A616_RS30600 81266415d87ef64f0daa218fe146ce13 254 SUPERFAMILY SSF55909 3 253 1.35E-54 T 29-03-2018 A616_RS30835 29bf711afc006fcfec95e2e684e24212 107 Gene3D G3DSA:3.10.450.40 44 105 4.0E-16 T 29-03-2018 A616_RS30835 29bf711afc006fcfec95e2e684e24212 107 Pfam PF03413 Peptidase propeptide and YPEB domain 45 103 8.5E-14 T 29-03-2018 IPR025711 PepSY domain A616_RS19465 6f8a8739370b8fa96f9ec120257ad53c 250 Pfam PF13803 Domain of unknown function (DUF4184) 1 240 2.5E-68 T 29-03-2018 IPR025238 Protein of unknown function DUF4184 A616_RS16165 0214f2af08c2d026a455880e5c499a53 228 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 58 210 2.4E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS16165 0214f2af08c2d026a455880e5c499a53 228 SUPERFAMILY SSF52266 46 221 1.55E-26 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain A616_RS16165 0214f2af08c2d026a455880e5c499a53 228 Gene3D G3DSA:3.40.50.1110 25 223 5.5E-22 T 29-03-2018 A616_RS26130 cd69bf9ad02095d5130e47caa212ed30 346 Gene3D G3DSA:1.20.950.20 28 262 8.0E-32 T 29-03-2018 A616_RS26130 cd69bf9ad02095d5130e47caa212ed30 346 SUPERFAMILY SSF103501 43 55 2.09E-20 T 29-03-2018 IPR023234 NarG-like domain A616_RS26130 cd69bf9ad02095d5130e47caa212ed30 346 SUPERFAMILY SSF103501 91 266 2.09E-20 T 29-03-2018 IPR023234 NarG-like domain A616_RS21220 7a385674e21684570c116ee2235c65bf 141 Hamap MF_01197 Cell division protein SepF [sepF]. 1 139 20.224 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 A616_RS21220 7a385674e21684570c116ee2235c65bf 141 Pfam PF04472 Cell division protein SepF 61 131 2.9E-30 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A616_RS06665 5957f16a438c49f98aa589dc48f6b539 181 Gene3D G3DSA:3.40.50.850 1 180 2.5E-48 T 29-03-2018 A616_RS06665 5957f16a438c49f98aa589dc48f6b539 181 Pfam PF00857 Isochorismatase family 3 175 1.9E-36 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS06665 5957f16a438c49f98aa589dc48f6b539 181 SUPERFAMILY SSF52499 2 178 5.23E-49 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A616_RS17230 2e620379ee1bed6ee5b362b87184aed2 101 Gene3D G3DSA:3.90.215.10 1 97 9.8E-4 T 29-03-2018 IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 A616_RS24325 55311b6f54f70c54258317d0c637a71b 207 Pfam PF07987 Domain of unkown function (DUF1775) 26 142 5.3E-20 T 29-03-2018 IPR012533 YcnI-like A616_RS00855 232fb53eff8d415581db6eb040ed3732 141 Gene3D G3DSA:1.10.10.10 6 93 1.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS00855 232fb53eff8d415581db6eb040ed3732 141 Pfam PF01475 Ferric uptake regulator family 13 130 8.5E-27 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A616_RS00855 232fb53eff8d415581db6eb040ed3732 141 SUPERFAMILY SSF46785 4 134 2.54E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS10555 fd698422997b1cc9017d40ef5e4df6e1 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 8.6E-40 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10555 fd698422997b1cc9017d40ef5e4df6e1 103 SUPERFAMILY SSF141091 2 102 3.66E-38 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10555 fd698422997b1cc9017d40ef5e4df6e1 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A616_RS10555 fd698422997b1cc9017d40ef5e4df6e1 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 8.5E-41 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS10555 fd698422997b1cc9017d40ef5e4df6e1 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.94 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A616_RS30375 07176babab7bfcf3faedfb96d0d8194d 297 SUPERFAMILY SSF54001 8 261 7.6E-29 T 29-03-2018 A616_RS30375 07176babab7bfcf3faedfb96d0d8194d 297 Gene3D G3DSA:3.30.2140.10 2 278 9.9E-31 T 29-03-2018 A616_RS30375 07176babab7bfcf3faedfb96d0d8194d 297 Pfam PF00797 N-acetyltransferase 24 92 1.6E-8 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 A616_RS07020 eb174ff72cf714f8da17aa91f8b9c5ce 153 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 8 145 2.1E-24 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 A616_RS28115 4561b80eb8a276deb327f9ff3e4764b1 217 Gene3D G3DSA:1.10.10.10 149 212 9.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS18865 27b7ee793652f8f0aeb939b15989d72e 125 Pfam PF11181 Heat induced stress protein YflT 9 104 7.5E-20 T 29-03-2018 IPR025889 General stress protein 17M-like domain A616_RS29635 39487ca6fe5ba7eaa554013a6d8e7b3c 331 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 191 305 7.6E-28 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type A616_RS29635 39487ca6fe5ba7eaa554013a6d8e7b3c 331 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 59 163 1.3E-24 T 29-03-2018 IPR030910 SLAP domain, Bacillus-type A616_RS05665 d7bf62e1e060935c94762328aa72f68d 187 PIRSF PIRSF016661 1 179 1.1E-45 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A616_RS05665 d7bf62e1e060935c94762328aa72f68d 187 Pfam PF02632 BioY family 31 170 1.4E-36 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A616_RS20195 3cddc73156d5051f68c1e997ad866d4c 96 Pfam PF01312 FlhB HrpN YscU SpaS Family 14 86 1.3E-22 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A616_RS20195 3cddc73156d5051f68c1e997ad866d4c 96 Gene3D G3DSA:3.40.1690.10 5 92 9.6E-32 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A616_RS20195 3cddc73156d5051f68c1e997ad866d4c 96 SUPERFAMILY SSF160544 12 90 3.79E-27 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A616_RS23270 a44d54c2dfe1a3522dfa3eb21fa69120 190 Pfam PF14065 Protein of unknown function (DUF4255) 9 177 2.7E-27 T 29-03-2018 IPR025351 Protein of unknown function DUF4255 A616_RS02680 30509eef8b48fd4f1121a70ce5135295 374 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 12 362 3.1E-62 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS02680 30509eef8b48fd4f1121a70ce5135295 374 Pfam PF03845 Spore germination protein 12 326 1.1E-80 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS03710 d28b4ee1bb518e34275b8ff5080a4240 975 Gene3D G3DSA:2.60.120.260 754 901 3.0E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS03710 d28b4ee1bb518e34275b8ff5080a4240 975 SUPERFAMILY SSF49785 755 877 1.21E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like A616_RS22375 55228c4ab18751e0ed523846416672e2 146 Pfam PF06695 Putative small multi-drug export protein 17 127 8.5E-11 T 29-03-2018 IPR009577 Putative small multi-drug export A616_RS06430 27a54f2d27abc182ac094b8b6d145dbe 144 Pfam PF10934 Protein of unknown function (DUF2634) 24 127 1.4E-18 T 29-03-2018 IPR020288 Protein of unknown function DUF2634 A616_RS06430 27a54f2d27abc182ac094b8b6d145dbe 144 Gene3D G3DSA:3.10.450.40 17 141 6.8E-7 T 29-03-2018 A616_RS06865 a19c15ea15df94ad3e61977462f7c48e 320 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 156 4.7E-21 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A616_RS09005 08faf4b36c6c8cb8093f15e72b8c02bf 400 Pfam PF01548 Transposase 5 163 5.4E-34 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 A616_RS09005 08faf4b36c6c8cb8093f15e72b8c02bf 400 Gene3D G3DSA:1.10.150.20 174 286 0.002 T 29-03-2018 A616_RS09005 08faf4b36c6c8cb8093f15e72b8c02bf 400 Pfam PF02371 Transposase IS116/IS110/IS902 family 274 361 8.0E-28 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 A616_RS09005 08faf4b36c6c8cb8093f15e72b8c02bf 400 Gene3D G3DSA:1.10.150.20 287 369 0.0024 T 29-03-2018 A616_RS02570 7c69860db445531ef9756a04b1532176 328 SUPERFAMILY SSF52540 24 237 2.61E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02570 7c69860db445531ef9756a04b1532176 328 SMART SM00382 39 224 4.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain A616_RS02570 7c69860db445531ef9756a04b1532176 328 Gene3D G3DSA:3.40.50.300 1 280 1.8E-53 T 29-03-2018 A616_RS02570 7c69860db445531ef9756a04b1532176 328 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A616_RS02570 7c69860db445531ef9756a04b1532176 328 Pfam PF00005 ABC transporter 32 174 1.6E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A616_RS12195 61def715a8c8a2029ea426b5a409aba0 84 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 80 1.1E-21 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A616_RS15855 5aa83eba66da130088c4b91d716126eb 315 SUPERFAMILY SSF161098 100 314 9.42E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15855 5aa83eba66da130088c4b91d716126eb 315 Gene3D G3DSA:1.10.3720.10 44 315 3.5E-42 T 29-03-2018 A616_RS15855 5aa83eba66da130088c4b91d716126eb 315 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 76 3.6E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A616_RS15855 5aa83eba66da130088c4b91d716126eb 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 315 1.0E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS26390 e8555e46d69ab87c7da323b475889268 111 SUPERFAMILY SSF52833 3 102 8.72E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS26390 e8555e46d69ab87c7da323b475889268 111 Gene3D G3DSA:3.40.30.30 1 99 1.3E-37 T 29-03-2018 A616_RS26390 e8555e46d69ab87c7da323b475889268 111 Pfam PF07315 Protein of unknown function (DUF1462) 7 97 1.4E-37 T 29-03-2018 IPR009190 Protein of unknown function DUF1462 A616_RS04585 4bf8c4456190d852e34dee8d5dd298a4 346 PIRSF PIRSF005508 1 346 3.5E-142 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A616_RS04585 4bf8c4456190d852e34dee8d5dd298a4 346 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 4 333 1.4E-142 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A616_RS04585 4bf8c4456190d852e34dee8d5dd298a4 346 Pfam PF01758 Sodium Bile acid symporter family 49 245 5.1E-68 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A616_RS22500 bde0f3c23a69e4b2a4c18f4606722f76 341 Pfam PF00296 Luciferase-like monooxygenase 26 314 2.9E-38 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS22500 bde0f3c23a69e4b2a4c18f4606722f76 341 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 15 337 2.1E-132 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 A616_RS22500 bde0f3c23a69e4b2a4c18f4606722f76 341 Gene3D G3DSA:3.20.20.30 18 341 2.9E-77 T 29-03-2018 A616_RS22500 bde0f3c23a69e4b2a4c18f4606722f76 341 SUPERFAMILY SSF51679 13 336 1.88E-86 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 A616_RS17770 84312ec9b4fc5933530eac04fa31b1f0 267 Gene3D G3DSA:3.40.33.10 141 263 7.9E-23 T 29-03-2018 IPR014044 CAP domain A616_RS17770 84312ec9b4fc5933530eac04fa31b1f0 267 SUPERFAMILY SSF55797 146 265 3.01E-26 T 29-03-2018 IPR014044 CAP domain A616_RS17770 84312ec9b4fc5933530eac04fa31b1f0 267 Pfam PF00188 Cysteine-rich secretory protein family 155 259 1.0E-22 T 29-03-2018 IPR014044 CAP domain A616_RS17770 84312ec9b4fc5933530eac04fa31b1f0 267 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 149 267 3.6E-54 T 29-03-2018 IPR014258 CAP domain, YkwD-like A616_RS01220 49b8a307bf701263302a00c63f15adc2 172 SUPERFAMILY SSF46600 131 170 3.53E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS01220 49b8a307bf701263302a00c63f15adc2 172 Gene3D G3DSA:4.10.860.10 98 172 5.4E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS01220 49b8a307bf701263302a00c63f15adc2 172 PIRSF PIRSF015034 1 172 3.7E-66 T 29-03-2018 IPR025542 YacH protein A616_RS01220 49b8a307bf701263302a00c63f15adc2 172 Pfam PF02151 UvrB/uvrC motif 134 167 2.9E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 A616_RS07880 b6dcebd687fd133ca38cb0a05813ada8 362 Gene3D G3DSA:3.30.1490.20 135 204 3.8E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A616_RS07880 b6dcebd687fd133ca38cb0a05813ada8 362 Pfam PF14398 YheC/D like ATP-grasp 100 355 2.8E-80 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D A616_RS07880 b6dcebd687fd133ca38cb0a05813ada8 362 Gene3D G3DSA:3.30.470.20 205 339 3.9E-17 T 29-03-2018 A616_RS07880 b6dcebd687fd133ca38cb0a05813ada8 362 SUPERFAMILY SSF56059 128 333 1.27E-15 T 29-03-2018 A616_RS17905 d67a275c22bd2e13df066e96242282bb 264 Pfam PF09844 Uncharacterized conserved protein (COG2071) 30 246 1.0E-70 T 29-03-2018 IPR018644 Protein of unknown function DUF2071 A616_RS17905 d67a275c22bd2e13df066e96242282bb 264 Gene3D G3DSA:2.40.400.10 21 258 2.4E-32 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A616_RS17905 d67a275c22bd2e13df066e96242282bb 264 SUPERFAMILY SSF160104 29 154 4.84E-14 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 A616_RS26460 6a2f90d0ae3b713302ef804b86f21af2 89 Pfam PF11256 Protein of unknown function (DUF3055) 8 86 2.1E-37 T 29-03-2018 IPR021415 Protein of unknown function DUF3055 A616_RS07475 b0a00461e334624d1c4354911c191e3a 663 Pfam PF00395 S-layer homology domain 496 538 4.3E-5 T 29-03-2018 IPR001119 S-layer homology domain A616_RS07475 b0a00461e334624d1c4354911c191e3a 663 Gene3D G3DSA:3.40.710.10 43 387 3.5E-76 T 29-03-2018 A616_RS07475 b0a00461e334624d1c4354911c191e3a 663 SUPERFAMILY SSF56601 50 371 2.68E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A616_RS07475 b0a00461e334624d1c4354911c191e3a 663 Pfam PF00144 Beta-lactamase 54 373 6.0E-58 T 29-03-2018 IPR001466 Beta-lactamase-related A616_RS29250 d082f2109b48887a1d0212d90a372ae5 122 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 109 2.1E-25 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV A616_RS01250 4dd45cb6e9d634d58172f85bf85aaf1c 131 Gene3D G3DSA:1.10.287.1080 2 124 6.7E-6 T 29-03-2018 A616_RS15120 d5e0587ff3daea19d05ef592579dcf1d 442 PIRSF PIRSF002746 1 442 1.4E-166 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A616_RS15120 d5e0587ff3daea19d05ef592579dcf1d 442 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 442 4.8E-166 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A616_RS15120 d5e0587ff3daea19d05ef592579dcf1d 442 Pfam PF02447 GntP family permease 1 439 1.7E-179 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A616_RS02395 cf51206fe336279a548c4b19bfaea1e0 210 SUPERFAMILY SSF55469 11 206 7.85E-55 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS02395 cf51206fe336279a548c4b19bfaea1e0 210 Gene3D G3DSA:3.40.109.10 10 210 3.5E-46 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A616_RS02395 cf51206fe336279a548c4b19bfaea1e0 210 Pfam PF00881 Nitroreductase family 14 188 4.2E-33 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A616_RS17720 c016a3adb1c1360e5c0ba698a9eb2019 731 Pfam PF05569 BlaR1 peptidase M56 14 332 2.9E-48 T 29-03-2018 IPR008756 Peptidase M56 A616_RS17720 c016a3adb1c1360e5c0ba698a9eb2019 731 Gene3D G3DSA:3.30.2010.10 119 250 1.1E-4 T 29-03-2018 A616_RS23345 a5772800374815e5e2a4ba447a79708a 406 Gene3D G3DSA:3.80.10.10 61 328 4.0E-8 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A616_RS23345 a5772800374815e5e2a4ba447a79708a 406 SUPERFAMILY SSF52047 183 258 3.22E-5 T 29-03-2018 A616_RS22875 6bf697c93705c2b94567c0288e9ce971 103 Pfam PF14034 Sporulation protein YtrH 3 100 6.1E-36 T 29-03-2018 IPR025689 Sporulation protein YtrH A616_RS22140 90f44a54a94bcda69d0d05049fb0bee3 194 Pfam PF11518 Protein of unknown function (DUF3221) 19 121 4.6E-27 T 29-03-2018 IPR021598 Protein of unknown function DUF3221 A616_RS22140 90f44a54a94bcda69d0d05049fb0bee3 194 Gene3D G3DSA:2.40.50.140 39 123 4.3E-11 T 29-03-2018 A616_RS18640 e17bfd13d7c3455d1f711781c9507edf 96 Gene3D G3DSA:3.30.70.100 1 96 1.0E-21 T 29-03-2018 A616_RS18640 e17bfd13d7c3455d1f711781c9507edf 96 SUPERFAMILY SSF54909 1 79 1.11E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS18640 e17bfd13d7c3455d1f711781c9507edf 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 1.8E-17 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A616_RS28525 2cca8440d07230ce2e9ecde92b3bf468 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 23 96 1.1E-15 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A616_RS28525 2cca8440d07230ce2e9ecde92b3bf468 110 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 16 105 1.7E-25 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 A616_RS26935 4a9b1db474b562564c5fd97225c18e85 514 PIRSF PIRSF005690 26 510 2.6E-179 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS26935 4a9b1db474b562564c5fd97225c18e85 514 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 40 494 1.3E-178 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS06250 8829c8c7455b925605c92206dcbd2a86 250 Gene3D G3DSA:2.30.30.30 2 41 0.04 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 A616_RS20235 7e5b28d8a92fae669dd8cc32e7f1c594 145 Pfam PF11068 YlqD protein 2 133 1.1E-36 T 29-03-2018 IPR021297 YlqD protein A616_RS22480 f3f9c67118d871ce41f8b3fd42f08831 73 Gene3D G3DSA:1.10.10.60 38 67 0.0011 T 29-03-2018 A616_RS05565 7f75f14300510038aa76e33620c9c0b2 110 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 105 1.3E-31 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD A616_RS05215 fdffd87cee93a5ea0efff41f386a6c60 648 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 34 639 5.4E-228 T 29-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein A616_RS05215 fdffd87cee93a5ea0efff41f386a6c60 648 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 131 564 5.2E-101 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A616_RS10960 45ee1d02e2b984772bef8e193d33983a 55 Pfam PF13333 Integrase core domain 23 52 9.4E-8 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A616_RS00980 60d13a38200a470f447c06fa6d12715d 143 Pfam PF07811 TadE-like protein 18 60 9.7E-8 T 29-03-2018 IPR012495 TadE-like A616_RS09390 de8cb3aeabf2a635844aef7925c2547b 188 Pfam PF09335 SNARE associated Golgi protein 48 145 6.6E-13 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS03330 65af38cd0988c448aa18872b979d46cf 182 SUPERFAMILY SSF55486 31 181 6.29E-14 T 29-03-2018 A616_RS03330 65af38cd0988c448aa18872b979d46cf 182 Gene3D G3DSA:3.40.390.10 29 181 7.9E-12 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 A616_RS22945 b8f5c6f1707ba07c9ae82cfb15da7323 756 Pfam PF00395 S-layer homology domain 568 606 0.0078 T 29-03-2018 IPR001119 S-layer homology domain A616_RS22945 b8f5c6f1707ba07c9ae82cfb15da7323 756 Pfam PF00395 S-layer homology domain 695 734 8.7E-5 T 29-03-2018 IPR001119 S-layer homology domain A616_RS22945 b8f5c6f1707ba07c9ae82cfb15da7323 756 Pfam PF00395 S-layer homology domain 629 671 1.2E-5 T 29-03-2018 IPR001119 S-layer homology domain A616_RS22945 b8f5c6f1707ba07c9ae82cfb15da7323 756 Gene3D G3DSA:3.10.450.40 306 372 4.7E-4 T 29-03-2018 A616_RS15470 badc62079b845446b23aebb3baa65e95 306 SUPERFAMILY SSF161098 89 290 6.05E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS15470 badc62079b845446b23aebb3baa65e95 306 Gene3D G3DSA:1.10.3720.10 1 293 5.5E-45 T 29-03-2018 A616_RS15470 badc62079b845446b23aebb3baa65e95 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 8.0E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A616_RS03740 f1731ed03302301f24241aa8dc00ec6b 1082 Gene3D G3DSA:2.60.120.560 891 1082 1.6E-20 T 29-03-2018 A616_RS03740 f1731ed03302301f24241aa8dc00ec6b 1082 Pfam PF06439 Domain of Unknown Function (DUF1080) 942 1082 6.5E-7 T 29-03-2018 IPR010496 Domain of unknown function DUF1080 A616_RS31720 708486eb3c76d6ef0b1dd44f2bf4d59e 261 SMART SM00062 38 260 1.6E-70 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS31720 708486eb3c76d6ef0b1dd44f2bf4d59e 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 258 2.0E-67 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A616_RS31720 708486eb3c76d6ef0b1dd44f2bf4d59e 261 SUPERFAMILY SSF53850 1 257 9.32E-74 T 29-03-2018 A616_RS31720 708486eb3c76d6ef0b1dd44f2bf4d59e 261 SMART SM00079 38 259 6.8E-7 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A616_RS31720 708486eb3c76d6ef0b1dd44f2bf4d59e 261 Gene3D G3DSA:3.40.190.10 1 157 2.4E-41 T 29-03-2018 A616_RS31720 708486eb3c76d6ef0b1dd44f2bf4d59e 261 Gene3D G3DSA:3.40.190.10 158 261 4.6E-18 T 29-03-2018 A616_RS11025 75b23117cc655eb3659498150d2cd4c1 263 Pfam PF11155 Domain of unknown function (DUF2935) 136 252 9.5E-33 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 A616_RS11025 75b23117cc655eb3659498150d2cd4c1 263 Pfam PF11155 Domain of unknown function (DUF2935) 8 122 5.9E-32 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 A616_RS11025 75b23117cc655eb3659498150d2cd4c1 263 SUPERFAMILY SSF158430 131 256 1.83E-39 T 29-03-2018 A616_RS11025 75b23117cc655eb3659498150d2cd4c1 263 SUPERFAMILY SSF158430 3 127 3.01E-39 T 29-03-2018 A616_RS17295 a6f3a9c427a66305cbc90e3886a550d0 73 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 4 49 4.5E-10 T 29-03-2018 IPR022453 Zinc finger, MqsA-type A616_RS30125 3b7413b20f364fa419b2a350994e8872 207 SUPERFAMILY SSF52833 43 172 3.02E-11 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS30125 3b7413b20f364fa419b2a350994e8872 207 Gene3D G3DSA:3.40.30.10 32 200 4.5E-10 T 29-03-2018 A616_RS06145 e336fa0637f650d018aebadc7a501e0e 186 Gene3D G3DSA:1.20.1270.30 8 87 0.03 T 29-03-2018 A616_RS06145 e336fa0637f650d018aebadc7a501e0e 186 Gene3D G3DSA:1.20.1270.30 125 186 0.08 T 29-03-2018 A616_RS21360 186b486910f18612d94f221d033b3384 350 Pfam PF00395 S-layer homology domain 49 87 1.1E-11 T 29-03-2018 IPR001119 S-layer homology domain A616_RS21360 186b486910f18612d94f221d033b3384 350 Pfam PF00395 S-layer homology domain 189 214 9.9E-9 T 29-03-2018 IPR001119 S-layer homology domain A616_RS19940 df2d7d9a9222ef21b8faddf37c8292ea 448 SMART SM00962 256 447 3.6E-56 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS19940 df2d7d9a9222ef21b8faddf37c8292ea 448 Pfam PF00448 SRP54-type protein, GTPase domain 259 446 3.3E-41 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A616_RS19940 df2d7d9a9222ef21b8faddf37c8292ea 448 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 2 343 1.0E-72 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 A616_RS19940 df2d7d9a9222ef21b8faddf37c8292ea 448 Gene3D G3DSA:3.40.50.300 255 435 4.3E-20 T 29-03-2018 A616_RS19940 df2d7d9a9222ef21b8faddf37c8292ea 448 SUPERFAMILY SSF52540 250 445 1.04E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS02315 50f842798c0632614fb53ad5c95ec1c6 552 Pfam PF13786 Domain of unknown function (DUF4179) 95 179 2.1E-14 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 A616_RS02315 50f842798c0632614fb53ad5c95ec1c6 552 Gene3D G3DSA:2.60.40.1630 123 269 6.2E-18 T 29-03-2018 A616_RS02315 50f842798c0632614fb53ad5c95ec1c6 552 Gene3D G3DSA:2.60.40.1640 470 552 0.066 T 29-03-2018 A616_RS02315 50f842798c0632614fb53ad5c95ec1c6 552 Gene3D G3DSA:2.60.40.1640 283 455 5.4E-14 T 29-03-2018 A616_RS11655 f6f6a868e34cbf172641cdea0a9aa133 51 Pfam PF14006 YqzL-like protein 4 47 3.2E-18 T 29-03-2018 IPR025617 YqzL-like protein A616_RS12135 27bcfe2da032408e58c0ef46b6bdd7dd 276 Pfam PF11299 Protein of unknown function (DUF3100) 21 255 1.1E-91 T 29-03-2018 IPR021450 Protein of unknown function DUF3100 A616_RS30925 6850834e4e0a8747a55245d5ab23609f 155 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 152 1.5E-34 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component A616_RS13760 e471b895fee4925fe2f7870645b0bd84 289 Pfam PF01040 UbiA prenyltransferase family 26 271 2.2E-52 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A616_RS13760 e471b895fee4925fe2f7870645b0bd84 289 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 5 287 5.8E-96 T 29-03-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related A616_RS09555 b75fb495f2be397a175fd74f7b3de1c2 376 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 363 4.0E-58 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS09555 b75fb495f2be397a175fd74f7b3de1c2 376 Pfam PF03845 Spore germination protein 10 323 1.1E-52 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS07650 bdce4f9f03985ff74ac75aa67a7152c1 145 Gene3D G3DSA:1.25.40.290 28 143 0.0013 T 29-03-2018 A616_RS21130 bb48676f9a8e35371642e38440e04ffc 83 Pfam PF10676 Spore germination protein gerPA/gerPF 1 61 3.4E-15 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF A616_RS09950 6205e830da14b950630eadc183e45bf1 276 Gene3D G3DSA:2.60.40.1120 76 271 0.0021 T 29-03-2018 A616_RS05600 8fbececc1081d925e1c226a6ccd73fe9 355 ProDom PD140749 ORF PHAGE PA0727 170 285 0.004 T 29-03-2018 A616_RS18000 13561262aedc347202c4f3e317bb3874 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 7.3E-107 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A616_RS18000 13561262aedc347202c4f3e317bb3874 256 SUPERFAMILY SSF110399 2 241 3.53E-79 T 29-03-2018 A616_RS18000 13561262aedc347202c4f3e317bb3874 256 Gene3D G3DSA:3.20.20.70 1 256 1.0E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A616_RS18000 13561262aedc347202c4f3e317bb3874 256 Hamap MF_00443 Thiazole synthase [thiG]. 3 256 41.823 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A616_RS15415 b28dacb5067ef670b115e917769dbefe 152 SUPERFAMILY SSF54637 6 151 7.9E-41 T 29-03-2018 IPR029069 HotDog domain A616_RS15415 b28dacb5067ef670b115e917769dbefe 152 Pfam PF01575 MaoC like domain 18 120 5.8E-24 T 29-03-2018 IPR002539 MaoC-like domain A616_RS15415 b28dacb5067ef670b115e917769dbefe 152 Gene3D G3DSA:3.10.129.10 1 152 3.5E-36 T 29-03-2018 A616_RS00975 0248f58643c824512632286daa31f0bf 165 Pfam PF01478 Type IV leader peptidase family 5 103 1.3E-14 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A616_RS03370 20b4a2ed66624b6d7a118e6867d33bc0 466 Pfam PF16933 Putative exopolysaccharide Exporter (EPS-E) 1 453 2.8E-140 T 29-03-2018 IPR031617 Putative exopolysaccharide exporter A616_RS31475 a5a0f2232bc4bd98a9198c417940611c 512 Gene3D G3DSA:3.80.10.10 20 466 1.7E-8 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like A616_RS18880 ccb8f7846649c5d11908f33c292d51e7 288 Pfam PF12679 ABC-2 family transporter protein 10 265 1.8E-16 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 A616_RS05885 400072ea584f37d7c48936d1dd2e077c 917 Gene3D G3DSA:3.55.50.10 102 200 1.2E-10 T 29-03-2018 A616_RS05885 400072ea584f37d7c48936d1dd2e077c 917 SUPERFAMILY SSF69279 72 177 2.95E-16 T 29-03-2018 A616_RS05885 400072ea584f37d7c48936d1dd2e077c 917 Gene3D G3DSA:2.40.50.260 266 369 9.6E-4 T 29-03-2018 A616_RS22235 7b9b7ad0fdd6be1e655a7c504484c00d 241 Pfam PF02535 ZIP Zinc transporter 95 206 2.8E-17 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A616_RS13685 9a38be673e46edd2edd195d6b13cf47c 88 Pfam PF14069 Stage VI sporulation protein F 9 83 2.5E-22 T 29-03-2018 IPR025942 Stage VI sporulation protein F A616_RS31600 5bb67e34a3bc12563e6f1bf2fa3024d9 327 Gene3D G3DSA:1.10.3470.10 1 327 7.3E-76 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS31600 5bb67e34a3bc12563e6f1bf2fa3024d9 327 Pfam PF01032 FecCD transport family 16 322 1.5E-93 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A616_RS31600 5bb67e34a3bc12563e6f1bf2fa3024d9 327 SUPERFAMILY SSF81345 4 323 2.22E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like A616_RS00815 9d757e56e2c2a52d818a389c130429c6 250 Pfam PF00756 Putative esterase 10 162 1.4E-23 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A616_RS00815 9d757e56e2c2a52d818a389c130429c6 250 SUPERFAMILY SSF53474 10 248 4.25E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS00815 9d757e56e2c2a52d818a389c130429c6 250 Gene3D G3DSA:3.40.50.1820 4 250 4.4E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold A616_RS17920 3170846d6e06ba91bb975e04a848f961 447 Pfam PF05525 Branched-chain amino acid transport protein 6 429 4.7E-149 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A616_RS17920 3170846d6e06ba91bb975e04a848f961 447 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 417 3.7E-131 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A616_RS03465 d91b61bfe6376b81edd424fd0e6128ea 222 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 13 59 6.9E-6 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal A616_RS06125 527d514e1907835b7596f3d2654a4a14 322 Pfam PF12671 Putative amidase domain 161 316 2.0E-36 T 29-03-2018 IPR024301 Putative amidase domain A616_RS06125 527d514e1907835b7596f3d2654a4a14 322 Gene3D G3DSA:3.90.1720.10 155 319 2.3E-15 T 29-03-2018 A616_RS21950 77d0fb60d13fefc6116b48d571ac23fa 187 SUPERFAMILY SSF159275 2 184 6.41E-51 T 29-03-2018 A616_RS21950 77d0fb60d13fefc6116b48d571ac23fa 187 Pfam PF06475 Putative glycolipid-binding 6 184 1.7E-54 T 29-03-2018 IPR009467 Putative glycolipid-binding protein A616_RS03180 96934d5e5be1b5052289beb3d1e84cb5 161 Pfam PF15631 NTF2 fold immunity protein 102 160 2.0E-15 T 29-03-2018 IPR028921 NTF2 fold domain A616_RS24010 450a979aff609051c944058ed11db3ad 212 Pfam PF01810 LysE type translocator 12 201 1.4E-36 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A616_RS15655 d37182b025b86ed9724b9dd9f8ce7349 382 Pfam PF01594 AI-2E family transporter 20 367 7.7E-48 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like A616_RS09595 1d78646b7e0c0c70d0c35faff32f61dd 124 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 4 103 9.2E-16 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV A616_RS14505 e1f41a3bc203777c42848d9b38f0ee78 487 Pfam PF07690 Major Facilitator Superfamily 16 405 1.4E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A616_RS14505 e1f41a3bc203777c42848d9b38f0ee78 487 Gene3D G3DSA:1.20.1250.20 256 484 5.0E-30 T 29-03-2018 A616_RS14505 e1f41a3bc203777c42848d9b38f0ee78 487 SUPERFAMILY SSF103473 444 474 1.4E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS14505 e1f41a3bc203777c42848d9b38f0ee78 487 SUPERFAMILY SSF103473 7 200 1.4E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS14505 e1f41a3bc203777c42848d9b38f0ee78 487 SUPERFAMILY SSF103473 246 416 1.4E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain A616_RS14505 e1f41a3bc203777c42848d9b38f0ee78 487 Gene3D G3DSA:1.20.1250.20 2 198 8.0E-34 T 29-03-2018 A616_RS25515 24ffdcc2c9a930c1158b47e3b4b9320b 562 Pfam PF13552 Protein of unknown function (DUF4127) 42 551 1.1E-141 T 29-03-2018 IPR025394 Protein of unknown function DUF4127 A616_RS20925 2667d9829c75cce9dd9766c10f9822a2 171 SUPERFAMILY SSF109854 9 166 1.68E-32 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes A616_RS20925 2667d9829c75cce9dd9766c10f9822a2 171 Gene3D G3DSA:1.20.120.450 23 167 3.0E-23 T 29-03-2018 A616_RS20925 2667d9829c75cce9dd9766c10f9822a2 171 Pfam PF12867 DinB superfamily 31 161 4.1E-18 T 29-03-2018 IPR024775 DinB-like domain A616_RS06485 3d94f5f0311411f2aeeafcc8d56071d9 477 SUPERFAMILY SSF55811 332 471 1.65E-13 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A616_RS06485 3d94f5f0311411f2aeeafcc8d56071d9 477 Gene3D G3DSA:3.90.79.10 330 473 6.3E-10 T 29-03-2018 A616_RS10585 b68c64c25c022a2dba5ea0669b4525fd 151 Pfam PF07849 Protein of unknown function (DUF1641) 115 140 6.9E-8 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 A616_RS23795 0017d582e5af1071bd45e4a331aada84 133 Gene3D G3DSA:2.80.10.50 5 97 7.5E-4 T 29-03-2018 A616_RS27050 7b54b8c56503418c0b9826f13ea65234 185 Pfam PF16107 Domain of unknown function (DUF4825) 54 135 1.3E-15 T 29-03-2018 IPR032250 Domain of unknown function DUF4825 A616_RS28975 5aee40ca0c706db44bb43c552d9e9ae0 80 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 7 75 3.1E-21 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A616_RS28975 5aee40ca0c706db44bb43c552d9e9ae0 80 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 6.5E-12 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A616_RS28975 5aee40ca0c706db44bb43c552d9e9ae0 80 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 6.5E-12 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A616_RS28975 5aee40ca0c706db44bb43c552d9e9ae0 80 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 6.5E-12 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A616_RS28975 5aee40ca0c706db44bb43c552d9e9ae0 80 Pfam PF03840 Preprotein translocase SecG subunit 6 75 1.3E-21 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A616_RS12030 1f5b0bf936c03e8a2640ccc94d78526c 213 PIRSF PIRSF000705 1 212 9.9E-55 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 A616_RS12030 1f5b0bf936c03e8a2640ccc94d78526c 213 Pfam PF01712 Deoxynucleoside kinase 6 202 3.1E-44 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain A616_RS12030 1f5b0bf936c03e8a2640ccc94d78526c 213 Gene3D G3DSA:3.40.50.300 1 207 2.4E-34 T 29-03-2018 A616_RS12030 1f5b0bf936c03e8a2640ccc94d78526c 213 SUPERFAMILY SSF52540 1 205 1.41E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS22585 ce9bf56072a7ecf7402fa0b22ca72031 219 Pfam PF11167 Protein of unknown function (DUF2953) 129 179 8.2E-11 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 A616_RS02625 4b9a3513f12d53a9e13463091198f856 112 Pfam PF13028 Protein of unknown function (DUF3889) 20 110 8.9E-33 T 29-03-2018 IPR024987 Protein of unknown function DUF3889 A616_RS09115 e5609524ed2fad8c202e47a993c47bf1 111 Pfam PF13564 DoxX-like family 5 102 1.8E-11 T 29-03-2018 IPR032808 DoxX family A616_RS06100 fb323ff694099ec8a67a18e2f148e939 442 Pfam PF00860 Permease family 16 395 1.5E-61 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS11035 5c3718beee98e6950f416f2f35975e3f 141 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 138 2.4E-32 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ A616_RS06380 815c167ae461e93dfaed6737d4f11838 160 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 4 90 4.1E-6 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A616_RS06380 815c167ae461e93dfaed6737d4f11838 160 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 3 152 5.0E-16 T 29-03-2018 A616_RS29050 ce23be4c4ac30d13822be72445b968d7 454 Pfam PF03553 Na+/H+ antiporter family 192 435 3.5E-10 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A616_RS09370 1f9096f257fd2218233ddcc1fd7dfa1d 140 Pfam PF07486 Cell Wall Hydrolase 24 129 1.4E-18 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 A616_RS15835 4749d9fb6026265f83514bc6bb9831a3 191 Pfam PF07849 Protein of unknown function (DUF1641) 151 182 1.0E-4 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 A616_RS15835 4749d9fb6026265f83514bc6bb9831a3 191 Gene3D G3DSA:1.25.10.10 3 190 5.0E-4 T 29-03-2018 IPR011989 Armadillo-like helical A616_RS08975 f3c84df8289be27a8d37803d3b2bfc57 129 Pfam PF08858 IDEAL domain 77 97 4.0E-5 T 29-03-2018 IPR014957 IDEAL domain A616_RS24925 0b5ed38d9d53e80bde204afd5154ef64 85 Gene3D G3DSA:3.30.70.790 14 84 4.6E-4 T 29-03-2018 A616_RS12655 f5a754461602d1ff9bb8c517b425d1f3 169 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 159 6.0E-31 T 29-03-2018 IPR020229 Uncharacterised protein YlaL A616_RS12655 f5a754461602d1ff9bb8c517b425d1f3 169 Gene3D G3DSA:3.90.420.10 83 169 4.2E-5 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 A616_RS27125 fa48c46b5f04eefebaf5cad63614cf3e 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 10 25 1.4E-6 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 SMART SM00418 13 94 7.2E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 Gene3D G3DSA:1.10.10.10 7 90 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 45 9.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 9.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 9.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 9.9E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 2.1E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A616_RS02835 ef0c32b6001d6b29d3e8657714ec0500 111 SUPERFAMILY SSF46785 3 91 1.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS27180 487d70726f97e3b835fed1b7a67de478 392 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 217 375 5.2E-14 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS27180 487d70726f97e3b835fed1b7a67de478 392 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 8 377 5.2E-49 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 A616_RS19555 d918a1134b7e201e215ca9437ead50aa 379 Pfam PF01757 Acyltransferase family 11 350 2.3E-23 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS08690 440491c4f1b2a1b9db5ff663eca52e0c 286 Pfam PF00395 S-layer homology domain 27 71 3.5E-12 T 29-03-2018 IPR001119 S-layer homology domain A616_RS32010 c5bb6e601db38dbe511fb54c5caaf3c8 311 Pfam PF14158 YndJ-like protein 32 292 7.0E-35 T 29-03-2018 IPR025450 YndJ-like protein A616_RS15240 8234d24deed449ec77d142740ea24384 163 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 33 151 6.1E-11 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 A616_RS15240 8234d24deed449ec77d142740ea24384 163 Gene3D G3DSA:3.30.530.20 26 153 1.0E-17 T 29-03-2018 IPR023393 START-like domain A616_RS15240 8234d24deed449ec77d142740ea24384 163 SUPERFAMILY SSF55961 28 153 4.08E-19 T 29-03-2018 A616_RS13075 e09ef9d349aa433bd7215fa5f6edee4d 225 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 215 1.7E-39 T 29-03-2018 IPR014245 Sporulation stage III, protein AF A616_RS13075 e09ef9d349aa433bd7215fa5f6edee4d 225 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 113 3.4E-21 T 29-03-2018 IPR014245 Sporulation stage III, protein AF A616_RS11895 12517a1f6c2b19e56a6616f52c5976bd 272 Gene3D G3DSA:1.25.10.10 22 242 2.3E-8 T 29-03-2018 IPR011989 Armadillo-like helical A616_RS11895 12517a1f6c2b19e56a6616f52c5976bd 272 SUPERFAMILY SSF48371 65 235 6.33E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 A616_RS22365 0806e66908d21e2b678970e922f0ff39 86 ProDom PD065427 YUSU IG COIL COILED BH3491 6 80 6.0E-12 T 29-03-2018 IPR020393 Uncharacterised protein family YusU A616_RS22365 0806e66908d21e2b678970e922f0ff39 86 Pfam PF10835 Protein of unknown function (DUF2573) 7 84 1.6E-37 T 29-03-2018 IPR020393 Uncharacterised protein family YusU A616_RS22365 0806e66908d21e2b678970e922f0ff39 86 Gene3D G3DSA:3.40.50.1220 26 86 0.0011 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A616_RS05505 005b35ae001b59ff6e902b8432ed7854 361 Gene3D G3DSA:2.60.40.1180 234 303 0.12 T 29-03-2018 A616_RS19220 40d89d162e84e0e6f77d357571cba9f9 142 Pfam PF14040 Deoxyribonuclease NucA/NucB 46 140 1.4E-13 T 29-03-2018 IPR029476 Deoxyribonuclease NucA/NucB A616_RS08615 067393eea141067d57eeaaa17c62e447 126 Gene3D G3DSA:3.10.180.10 1 126 1.1E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS08615 067393eea141067d57eeaaa17c62e447 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 120 4.6E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A616_RS08615 067393eea141067d57eeaaa17c62e447 126 SUPERFAMILY SSF54593 7 126 1.24E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS21050 16b95240e5c985d7b0b1b39e5b055fc9 213 SUPERFAMILY SSF56112 35 179 4.26E-13 T 29-03-2018 IPR011009 Protein kinase-like domain A616_RS21050 16b95240e5c985d7b0b1b39e5b055fc9 213 Gene3D G3DSA:1.10.510.10 34 179 3.6E-5 T 29-03-2018 A616_RS14550 1ac5b29955bc76cf9ad77600ef8f593a 194 Pfam PF09335 SNARE associated Golgi protein 38 157 2.1E-20 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS28190 0eda66f3b55c9e94a68769d416078747 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 319 6.5E-42 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A616_RS28190 0eda66f3b55c9e94a68769d416078747 332 Gene3D G3DSA:1.10.3470.10 34 331 9.9E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A616_RS12530 01d73d3a92066c8951d1979a05fceb58 199 Pfam PF04367 Protein of unknown function (DUF502) 54 155 2.3E-25 T 29-03-2018 IPR007462 Protein of unknown function DUF502 A616_RS25310 2b0644564e3e5a843a7e386eb6a7dc05 370 Pfam PF03845 Spore germination protein 6 322 3.8E-63 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS25310 2b0644564e3e5a843a7e386eb6a7dc05 370 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 362 9.7E-72 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS13335 7d3cb6e704b692950740ff501cb7a2f5 79 Pfam PF14004 Protein of unknown function (DUF4227) 6 79 2.0E-23 T 29-03-2018 IPR025321 Protein of unknown function DUF4227 A616_RS20595 c915e812221f9efc723812d92fc13861 298 Pfam PF00892 EamA-like transporter family 145 276 8.3E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS20595 c915e812221f9efc723812d92fc13861 298 Pfam PF00892 EamA-like transporter family 7 135 1.5E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A616_RS20595 c915e812221f9efc723812d92fc13861 298 SUPERFAMILY SSF103481 41 137 2.48E-8 T 29-03-2018 A616_RS20595 c915e812221f9efc723812d92fc13861 298 SUPERFAMILY SSF103481 184 277 3.01E-16 T 29-03-2018 A616_RS25855 d703e60c0e5cd6d82f3d342dd78899ae 444 Gene3D G3DSA:3.40.50.980 100 263 2.6E-8 T 29-03-2018 A616_RS25855 d703e60c0e5cd6d82f3d342dd78899ae 444 TIGRFAM TIGR02304 aden_form_hyp: putative adenylate-forming enzyme 3 436 3.0E-158 T 29-03-2018 IPR012685 Conserved hypothetical protein CHP02304, F390 synthetase-related A616_RS25855 d703e60c0e5cd6d82f3d342dd78899ae 444 SUPERFAMILY SSF56801 180 264 1.44E-6 T 29-03-2018 A616_RS18680 cb2a6804e196de8d9a1d26cfae91966d 155 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 147 2.2E-23 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 A616_RS28475 dd6d1aa34c6fb3de62f81c34a0f77f32 214 Gene3D G3DSA:3.40.1000.10 62 214 5.8E-19 T 29-03-2018 A616_RS30630 cfc07dbfb9f4bb2ee329ebb58665536d 449 Pfam PF00860 Permease family 22 398 3.3E-75 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS26820 92244e961506b22283ff96fbfad28e25 150 Gene3D G3DSA:3.40.30.10 1 138 5.7E-20 T 29-03-2018 A616_RS26820 92244e961506b22283ff96fbfad28e25 150 SUPERFAMILY SSF52833 3 138 3.36E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS26820 92244e961506b22283ff96fbfad28e25 150 Pfam PF00578 AhpC/TSA family 5 125 8.2E-14 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A616_RS16310 bc261934c4e4603d74b95ab00f6a442a 82 SUPERFAMILY SSF54909 2 78 3.96E-6 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel A616_RS16310 bc261934c4e4603d74b95ab00f6a442a 82 Gene3D G3DSA:3.30.70.100 1 78 3.6E-6 T 29-03-2018 A616_RS18940 7339825ee471e89b0d1bb17683d14e6b 351 Pfam PF10720 Protein of unknown function (DUF2515) 15 324 3.4E-106 T 29-03-2018 IPR019658 Protein of unknown function DUF2515 A616_RS10990 982dda8897d05c16a73ee519583b1108 162 Pfam PF03640 Secreted repeat of unknown function 56 95 2.6E-11 T 29-03-2018 IPR005297 Lipoprotein repeat A616_RS10990 982dda8897d05c16a73ee519583b1108 162 Pfam PF03640 Secreted repeat of unknown function 116 155 8.3E-17 T 29-03-2018 IPR005297 Lipoprotein repeat A616_RS10885 e893272ecac964bc4a628dd660e1bb3e 188 SUPERFAMILY SSF55729 2 182 4.8E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS10885 e893272ecac964bc4a628dd660e1bb3e 188 Pfam PF00583 Acetyltransferase (GNAT) family 39 164 1.2E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS10885 e893272ecac964bc4a628dd660e1bb3e 188 Gene3D G3DSA:3.40.630.30 1 188 6.2E-30 T 29-03-2018 A616_RS23665 41fad1ae868f8a917ac3f4c76a340d80 391 Pfam PF13490 Putative zinc-finger 9 36 3.3E-6 T 29-03-2018 IPR027383 Putative zinc-finger A616_RS23665 41fad1ae868f8a917ac3f4c76a340d80 391 Pfam PF14285 Domain of unknown function (DUF4367) 335 389 5.0E-5 T 29-03-2018 IPR025377 Domain of unknown function DUF4367 A616_RS10825 683a16cf56c9737ce1069107ac2dfc49 228 Pfam PF03741 Integral membrane protein TerC family 15 183 6.5E-45 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 A616_RS10825 683a16cf56c9737ce1069107ac2dfc49 228 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 184 5.3E-68 T 29-03-2018 IPR022301 Integral membrane protein YjbE A616_RS23420 0cc24ac68dc2ed2decf69b726da84071 465 Pfam PF01943 Polysaccharide biosynthesis protein 25 310 6.1E-16 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A616_RS23420 0cc24ac68dc2ed2decf69b726da84071 465 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 362 448 1.4E-14 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A616_RS01910 f1302a73224b7166e5b6efd2c87fa2d4 160 SUPERFAMILY SSF55729 1 146 3.06E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS01910 f1302a73224b7166e5b6efd2c87fa2d4 160 Pfam PF00583 Acetyltransferase (GNAT) family 39 135 8.7E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS01910 f1302a73224b7166e5b6efd2c87fa2d4 160 Gene3D G3DSA:3.40.630.30 1 136 4.0E-17 T 29-03-2018 A616_RS06265 854bf2a188e53a1408436c1bef3e64a0 311 Pfam PF04326 Putative DNA-binding domain 24 146 1.3E-12 T 29-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 A616_RS21100 738ef47fd7c5a155c9fc0ec7f8323586 134 Pfam PF03994 Domain of Unknown Function (DUF350) 12 65 5.2E-7 T 29-03-2018 IPR007140 Protein of unknown function DUF350 A616_RS23745 fe3aa15406531d4b198bd6d7bc7fc773 195 Pfam PF09335 SNARE associated Golgi protein 22 140 9.0E-10 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS05875 1e831ddba7888e65caf86287ad8ba2e8 207 Gene3D G3DSA:3.40.1000.10 34 207 5.5E-4 T 29-03-2018 A616_RS30795 e6fad484c6c438019953df70244d897d 355 Pfam PF03601 Conserved hypothetical protein 698 37 339 3.5E-75 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 A616_RS06765 fe8de0c2967d5cb58ff6ee6dfe7aade5 310 Gene3D G3DSA:3.90.70.10 7 172 4.0E-10 T 29-03-2018 A616_RS22860 2e757ce9401a2903def9c1bf4d095ce3 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 27 1.8E-5 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM A616_RS01010 6ef7445b998ad63c5fe3f29f9d7a01db 262 SMART SM00858 41 102 0.0064 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A616_RS01010 6ef7445b998ad63c5fe3f29f9d7a01db 262 Gene3D G3DSA:3.90.1210.10 40 103 2.6E-7 T 29-03-2018 A616_RS01010 6ef7445b998ad63c5fe3f29f9d7a01db 262 Pfam PF08666 SAF domain 44 101 7.0E-5 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A616_RS28300 7d1961859f086bf83640d28a33cb4588 189 Pfam PF07681 DoxX 29 135 7.3E-9 T 29-03-2018 IPR032808 DoxX family A616_RS24890 bb5ff355d929123a9f74df97e1eab154 303 Pfam PF11392 Protein of unknown function (DUF2877) 180 288 7.2E-27 T 29-03-2018 IPR021530 Protein of unknown function DUF2877 A616_RS20395 77f730c3da60be253750562a9ac57f2c 452 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 360 2.7E-47 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS20395 77f730c3da60be253750562a9ac57f2c 452 Pfam PF03845 Spore germination protein 8 319 2.1E-34 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 A616_RS30680 04068c02915aafba546619a732b71b81 180 Pfam PF14172 Domain of unknown function (DUF4309) 45 177 2.3E-19 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 A616_RS30680 04068c02915aafba546619a732b71b81 180 Gene3D G3DSA:3.30.1450.10 41 172 0.042 T 29-03-2018 A616_RS16600 32131cf82ea52f65c2a5dfee4a485583 606 SUPERFAMILY SSF52540 264 382 5.25E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16600 32131cf82ea52f65c2a5dfee4a485583 606 SUPERFAMILY SSF52540 1 194 5.25E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS16600 32131cf82ea52f65c2a5dfee4a485583 606 Pfam PF13175 AAA ATPase domain 1 381 1.4E-31 T 29-03-2018 A616_RS16600 32131cf82ea52f65c2a5dfee4a485583 606 Gene3D G3DSA:3.40.50.300 1 413 2.1E-26 T 29-03-2018 A616_RS28545 abf27005e66e489613a2754c04a8da43 506 PIRSF PIRSF005690 21 504 1.5E-164 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS28545 abf27005e66e489613a2754c04a8da43 506 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 36 490 4.2E-172 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 A616_RS03400 3d4a90b398c915ab8497696de0bd4032 104 SUPERFAMILY SSF52833 10 101 2.25E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold A616_RS03400 3d4a90b398c915ab8497696de0bd4032 104 Gene3D G3DSA:3.40.30.10 2 103 2.5E-8 T 29-03-2018 A616_RS18445 d063812b16c1dee291486a22e0e2e533 213 Pfam PF13021 Domain of unknown function (DUF3885) 171 208 3.0E-18 T 29-03-2018 IPR024976 Domain of unknown function DUF3885 A616_RS26180 72bb87e74cce86ffcc0846b88c8bb676 605 Pfam PF13520 Amino acid permease 27 444 3.6E-29 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A616_RS29740 cafa94081f9c516a1b17cdea71b73bb0 749 Pfam PF13753 Putative flagellar system-associated repeat 648 723 8.5E-5 T 29-03-2018 IPR028059 Putative flagellar system-associated repeat A616_RS08415 40aebf8ca299392dd5d476a9c75c0654 660 Pfam PF02687 FtsX-like permease family 561 650 4.6E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS08415 40aebf8ca299392dd5d476a9c75c0654 660 Pfam PF02687 FtsX-like permease family 265 362 9.0E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS08415 40aebf8ca299392dd5d476a9c75c0654 660 Pfam PF12704 MacB-like periplasmic core domain 20 209 7.3E-9 T 29-03-2018 IPR025857 MacB-like periplasmic core domain A616_RS07630 91355398c7920f190db60291a2d15c40 436 Gene3D G3DSA:1.10.10.10 352 435 9.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS22780 0f4cc05178615aae354a0bb09bb8f52a 74 Pfam PF07561 Domain of Unknown Function (DUF1540) 4 66 7.0E-18 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 A616_RS06975 cd6d8d5cd38f6ccb8cc227084509c958 178 Gene3D G3DSA:3.40.630.30 3 139 4.5E-18 T 29-03-2018 A616_RS06975 cd6d8d5cd38f6ccb8cc227084509c958 178 SUPERFAMILY SSF55729 2 171 9.86E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS06975 cd6d8d5cd38f6ccb8cc227084509c958 178 Pfam PF00583 Acetyltransferase (GNAT) family 29 134 1.6E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS06615 9d48bebedc964488db8c5e8260328b32 251 Pfam PF04892 VanZ like family 87 228 4.2E-21 T 29-03-2018 IPR006976 VanZ-like A616_RS05240 0923b459839551da7b60c24f85388da0 351 Pfam PF10776 Protein of unknown function (DUF2600) 20 350 1.0E-141 T 29-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 A616_RS05605 3176bfbdd1186fb6cbd51c6ee573259f 65 Pfam PF12728 Helix-turn-helix domain 14 63 2.7E-6 T 29-03-2018 A616_RS05605 3176bfbdd1186fb6cbd51c6ee573259f 65 Gene3D G3DSA:1.10.10.10 14 64 1.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS31200 7d4b5623ec2d22b8cf6aa2818ce22532 254 Pfam PF13349 Putative adhesin 90 226 8.4E-9 T 29-03-2018 IPR025164 Putative adhesin A616_RS28465 5a34babfdb43a9e3ef35468e6d55aea5 142 Gene3D G3DSA:2.60.120.380 21 137 4.6E-8 T 29-03-2018 A616_RS19195 3a75511bd3a8762f939dcd672212652e 79 Pfam PF10552 ORF6C domain 1 61 1.1E-13 T 29-03-2018 IPR018878 ORF6C domain A616_RS28490 4a56eca6d7a01dac864831fe3face2ba 168 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 7 161 5.6E-51 T 29-03-2018 IPR018681 Protein of unknown function DUF2165, transmembrane A616_RS01710 3c03094b88ff621354eac47edb33c0b6 415 Pfam PF07949 YbbR-like protein 138 220 1.9E-10 T 29-03-2018 IPR012505 YbbR-like A616_RS01710 3c03094b88ff621354eac47edb33c0b6 415 Pfam PF07949 YbbR-like protein 229 310 3.5E-14 T 29-03-2018 IPR012505 YbbR-like A616_RS11615 afd05b79a56c59c9e48dc63268eba3f3 65 Gene3D G3DSA:1.10.10.60 10 65 1.6E-4 T 29-03-2018 A616_RS28325 ebd2ef65d9c73b06d6bc0b719ad92444 119 Pfam PF01541 GIY-YIG catalytic domain 17 112 8.3E-7 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS28325 ebd2ef65d9c73b06d6bc0b719ad92444 119 Gene3D G3DSA:3.40.1440.10 15 119 2.2E-17 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS28325 ebd2ef65d9c73b06d6bc0b719ad92444 119 SUPERFAMILY SSF82771 16 113 4.18E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily A616_RS14300 fd1208b6de28c163fb8193b22bdc0781 278 Pfam PF02361 Cobalt transport protein 21 247 2.8E-34 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component A616_RS01015 e7c81e0509d44b524e9e49975a08b15d 372 SUPERFAMILY SSF52540 141 309 1.86E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A616_RS01015 e7c81e0509d44b524e9e49975a08b15d 372 Gene3D G3DSA:3.40.50.300 126 319 7.3E-8 T 29-03-2018 A616_RS06740 bf35c4b00d039d135e684c47fda35db1 132 SUPERFAMILY SSF51306 40 126 9.94E-7 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A616_RS20175 345916058a59fec3cbe43ba0046d44f3 184 SUPERFAMILY SSF143990 14 112 1.7E-23 T 29-03-2018 A616_RS13440 d6c3a67099ee97b2ff30cf498f597712 204 Pfam PF14097 Stage V sporulation protein AE1 7 187 6.1E-81 T 29-03-2018 IPR025914 Stage V sporulation protein AE A616_RS03925 a6f6f56effa0ef75136441c3b2860129 161 SUPERFAMILY SSF48452 10 143 7.11E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS03925 a6f6f56effa0ef75136441c3b2860129 161 Gene3D G3DSA:1.25.40.10 58 155 1.1E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS03925 a6f6f56effa0ef75136441c3b2860129 161 Gene3D G3DSA:1.25.40.10 8 57 1.8E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A616_RS03925 a6f6f56effa0ef75136441c3b2860129 161 Pfam PF12688 Tetratrico peptide repeat 35 156 1.2E-10 T 29-03-2018 A616_RS02565 54ffedb0e72fda624b8bc2f09e94e7f6 271 Pfam PF01061 ABC-2 type transporter 29 224 7.2E-11 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A616_RS25990 eb3a154ac60d4e40452904bd0db75944 432 Gene3D G3DSA:1.10.10.10 351 432 7.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS04245 e3f46249fdc279fbc5c840dadf01b8f1 153 Gene3D G3DSA:3.10.450.100 35 146 2.2E-4 T 29-03-2018 A616_RS04245 e3f46249fdc279fbc5c840dadf01b8f1 153 SUPERFAMILY SSF54427 41 132 8.24E-5 T 29-03-2018 IPR032710 NTF2-like domain A616_RS03605 4df892813a7cebc6c89f07c5bc9ec99b 327 Gene3D G3DSA:1.10.238.10 10 105 0.059 T 29-03-2018 A616_RS23065 4b3ec835c37263b0b27e45175c0b2bc0 282 Pfam PF04454 Encapsulating protein for peroxidase 4 264 4.9E-84 T 29-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 A616_RS26015 c794221d42d04e19bc1b50021f884739 163 Pfam PF10754 Protein of unknown function (DUF2569) 12 161 6.1E-34 T 29-03-2018 IPR019690 Protein of unknown function DUF2569 A616_RS21375 5bfb0013783bd9bdb4fc9b0971d92a60 132 Pfam PF11877 Protein of unknown function (DUF3397) 14 125 1.8E-22 T 29-03-2018 IPR024515 Protein of unknown function DUF3397 A616_RS25570 a10552331555651e1b67a8cd3fef464c 322 Pfam PF00953 Glycosyl transferase family 4 78 238 2.0E-40 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A616_RS06165 84feb7928c263f3267d734a5c875826c 29 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 4 25 1.2E-6 T 29-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) A616_RS22915 ca131100633a24ecd0412af0256b3eb5 815 Pfam PF06160 Septation ring formation regulator, EzrA 200 513 1.5E-33 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 A616_RS22915 ca131100633a24ecd0412af0256b3eb5 815 Pfam PF06160 Septation ring formation regulator, EzrA 658 792 2.7E-27 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 A616_RS22915 ca131100633a24ecd0412af0256b3eb5 815 Gene3D G3DSA:1.20.1480.30 290 473 0.15 T 29-03-2018 A616_RS09410 ffca90bcad977cc76c6495ab71ec5906 306 Pfam PF08812 YtxC-like family 70 282 1.3E-55 T 29-03-2018 IPR014199 Sporulation protein YtxC A616_RS06285 3cd9c51bca4665b894706224bd957f9b 112 Gene3D G3DSA:3.30.2120.10 1 112 8.8E-7 T 29-03-2018 A616_RS23120 191283381d5f7482a2e1dc4620c7a147 341 Pfam PF00899 ThiF family 5 243 2.4E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS23120 191283381d5f7482a2e1dc4620c7a147 341 SUPERFAMILY SSF69572 3 330 2.62E-83 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A616_RS23120 191283381d5f7482a2e1dc4620c7a147 341 Gene3D G3DSA:3.40.50.720 21 272 8.1E-63 T 29-03-2018 A616_RS14275 d3a7aae8cafe84c6f5735d21999d881a 111 Gene3D G3DSA:3.40.50.10400 5 102 5.0E-7 T 29-03-2018 IPR027269 Hypothetical PA1492 domain A616_RS09155 90080d16393bafccf67360358ff378a5 442 Pfam PF00474 Sodium:solute symporter family 17 377 2.9E-11 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS25170 27e67131af0a7f92264ca7aaff505c5e 201 SUPERFAMILY SSF109998 50 149 4.58E-8 T 29-03-2018 IPR027304 Trigger factor/SurA domain A616_RS25170 27e67131af0a7f92264ca7aaff505c5e 201 Gene3D G3DSA:1.10.4030.10 33 193 1.3E-9 T 29-03-2018 A616_RS26970 76effef48f7eca4df7a9240252f7bc8f 373 Pfam PF00395 S-layer homology domain 32 72 5.6E-10 T 29-03-2018 IPR001119 S-layer homology domain A616_RS17565 1a5c43b516a7c8d30df08df10bd0582b 109 Pfam PF04397 LytTr DNA-binding domain 13 104 3.5E-11 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS17565 1a5c43b516a7c8d30df08df10bd0582b 109 Gene3D G3DSA:2.40.50.40 3 70 2.4E-6 T 29-03-2018 A616_RS17565 1a5c43b516a7c8d30df08df10bd0582b 109 SMART SM00850 12 105 5.1E-8 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A616_RS10050 c5aaf9554342aa768895d0c37edd657b 115 Pfam PF07098 Protein of unknown function (DUF1360) 11 110 8.5E-34 T 29-03-2018 IPR010773 Mycobacterium phage PG1, Gp7 A616_RS16955 9ebe283b4298bf363c397dab3ac11f30 90 Gene3D G3DSA:1.10.10.10 2 90 1.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A616_RS20585 6b30aa8c21f6cd9b89dbc44c9df537ea 248 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 14 236 1.7E-63 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 A616_RS20585 6b30aa8c21f6cd9b89dbc44c9df537ea 248 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 17 229 1.5E-58 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 A616_RS09775 021f2f15799b5ca0de433a74a54a52fc 150 Pfam PF10702 Protein of unknown function (DUF2507) 27 147 3.0E-32 T 29-03-2018 IPR019642 Protein of unknown function DUF2507 A616_RS09775 021f2f15799b5ca0de433a74a54a52fc 150 Gene3D G3DSA:3.30.1380.20 10 141 7.8E-15 T 29-03-2018 A616_RS09775 021f2f15799b5ca0de433a74a54a52fc 150 SUPERFAMILY SSF111126 4 130 4.71E-19 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain A616_RS26725 44b01aa48c9fc5b808eef9affc5c1cd4 116 Pfam PF08863 YolD-like protein 14 111 5.9E-18 T 29-03-2018 IPR014962 YolD-like protein A616_RS06885 630a48edc109e0513d6e25a5cfe54804 112 Pfam PF07681 DoxX 8 87 3.0E-18 T 29-03-2018 IPR032808 DoxX family A616_RS08315 c3c23f5cc069bbc5180fa4f45943127b 253 Pfam PF14062 Domain of unknown function (DUF4253) 148 253 3.0E-27 T 29-03-2018 IPR025349 Domain of unknown function DUF4253 A616_RS03410 166dfabef5015361f5adb80fe25e969a 276 Gene3D G3DSA:3.90.1210.10 39 104 3.3E-9 T 29-03-2018 A616_RS26255 39199805ade18e9a03cec449c0ba9e81 86 Pfam PF14068 Putative membrane protein 5 47 8.4E-10 T 29-03-2018 IPR025917 Putative membrane protein YuiB A616_RS26255 39199805ade18e9a03cec449c0ba9e81 86 Pfam PF14068 Putative membrane protein 56 86 3.8E-8 T 29-03-2018 IPR025917 Putative membrane protein YuiB A616_RS18675 6f694953f3a6b10f6113b8d243e74dbc 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 446 2.8E-150 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A616_RS16970 b1fa093159e8a152e1bdf253719d33cf 467 Pfam PF14072 DNA-sulfur modification-associated 145 378 1.6E-7 T 29-03-2018 IPR017642 DNA sulphur modification protein DndB A616_RS25255 17ea3b13e5e5d95a4d3aa3027017b774 275 Pfam PF09929 Putative PD-(D/E)XK phosphodiesterase (DUF2161) 104 224 5.1E-38 T 29-03-2018 IPR018679 Putative PD-(D/E)XK phosphodiesterase (DUF2161) A616_RS22635 79bde92a07981d7ad901dec4615980d0 194 ProDom PD102989 YKOP PLASMID 1 183 4.0E-16 T 29-03-2018 A616_RS07525 5085182f14d37798a2e2bbb7db17e649 141 Pfam PF07485 Domain of Unknown Function (DUF1259) 19 137 1.7E-33 T 29-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO A616_RS01055 2f03a5dce375911dc4fcac75ba39ecb8 113 Pfam PF12986 Domain of unknown function (DUF3870) 8 100 6.5E-35 T 29-03-2018 IPR024617 Domain of unknown function DUF3870 A616_RS20435 a8b5ae8773edcb3fa3c6d11c5b15c950 205 Gene3D G3DSA:1.20.58.220 13 98 0.3 T 29-03-2018 A616_RS20435 a8b5ae8773edcb3fa3c6d11c5b15c950 205 Gene3D G3DSA:1.20.58.220 100 204 4.7E-6 T 29-03-2018 A616_RS20435 a8b5ae8773edcb3fa3c6d11c5b15c950 205 Pfam PF01865 Protein of unknown function DUF47 8 202 3.0E-34 T 29-03-2018 IPR018445 Putative phosphate transport regulator A616_RS11975 85517ecc4f47b1cf5e3660eea3cb4f43 334 Pfam PF03773 Predicted permease 47 332 1.5E-68 T 29-03-2018 IPR005524 Predicted permease DUF318 A616_RS19510 4112b153627dbd85cb413f7b92134eae 398 Gene3D G3DSA:3.20.20.80 2 302 6.9E-9 T 29-03-2018 A616_RS28405 d3efaaa9fde9977fd1302bcc096d45b1 288 Pfam PF10978 Protein of unknown function (DUF2785) 90 260 8.2E-52 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 A616_RS00785 fa98d4b752f47b4c89152f574c5ce160 148 Pfam PF12821 Threonine/Serine exporter, ThrE 7 131 4.0E-29 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE A616_RS19560 c730d63a92d0383542a028a827380151 156 SUPERFAMILY SSF54631 10 138 1.01E-25 T 29-03-2018 A616_RS19560 c730d63a92d0383542a028a827380151 156 Gene3D G3DSA:3.10.580.10 1 143 2.4E-16 T 29-03-2018 A616_RS14360 6a0ad2db37e551a1b42ec6c9b475e836 209 Pfam PF04294 VanW like protein 77 206 5.3E-46 T 29-03-2018 IPR007391 Vancomycin resistance VanW A616_RS21415 d021ee76f84746c82387a881b24e3d8c 213 Gene3D G3DSA:1.10.10.60 3 85 6.5E-5 T 29-03-2018 A616_RS21415 d021ee76f84746c82387a881b24e3d8c 213 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 78 8.3E-39 T 29-03-2018 IPR014243 Transcription factor, RsfA A616_RS00650 7fe345882e8b44359956378a490ab619 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 5.3E-8 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 A616_RS00650 7fe345882e8b44359956378a490ab619 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A616_RS18975 16e8e23eb54cbaff431cff20456f9e9e 354 Pfam PF09992 Phosphodiester glycosidase 173 354 6.9E-39 T 29-03-2018 IPR018711 Phosphodiester glycosidase A616_RS07545 b1bc7da4e2d0e7d907a39b495bbaf8d7 150 Pfam PF04463 Protein of unknown function (DUF523) 3 145 1.1E-44 T 29-03-2018 IPR007553 Domain of unknown function DUF523 A616_RS21605 219ae79752480f7c18286f90b1301d4b 99 Pfam PF11256 Protein of unknown function (DUF3055) 7 87 1.5E-31 T 29-03-2018 IPR021415 Protein of unknown function DUF3055 A616_RS29440 8bb5be41e8c427058d03673c729560a0 58 Pfam PF14070 Putative motility protein 2 56 2.5E-6 T 29-03-2018 IPR025906 Putative motility protein A616_RS03290 346fa65e18b79babd3f839a9fb8c32b0 193 Pfam PF02417 Chromate transporter 4 170 2.9E-37 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A616_RS00825 b70c0d4b89627011061ccb7ed749e363 430 Pfam PF01098 Cell cycle protein 82 421 3.7E-39 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A616_RS30890 c6cec41b7416687f478d04e007efd073 96 Gene3D G3DSA:3.40.630.40 1 95 7.9E-10 T 29-03-2018 A616_RS30890 c6cec41b7416687f478d04e007efd073 96 SUPERFAMILY SSF53187 2 89 1.44E-6 T 29-03-2018 A616_RS30890 c6cec41b7416687f478d04e007efd073 96 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 72 2.8E-6 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A616_RS20430 a72f46d27b6ff0bcd87c1e85b4ab4ff9 339 Pfam PF01384 Phosphate transporter family 25 328 3.6E-91 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A616_RS25320 8aef45d4da3531143454e9d12e2192f2 341 Pfam PF06089 L-asparaginase II 13 333 6.1E-93 T 29-03-2018 IPR010349 L-asparaginase II A616_RS17300 9cd8046da21082eebb8c0c7d185344b7 101 Pfam PF14076 Domain of unknown function (DUF4258) 7 64 4.0E-10 T 29-03-2018 IPR025354 Protein of unknown function DUF4258 A616_RS10830 b80eb7d4f4340558df19571a214f17a7 354 Pfam PF01594 AI-2E family transporter 34 346 6.8E-77 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like A616_RS00205 34b194a944207372bdf09807b57fc77c 337 Pfam PF14175 YaaC-like Protein 8 318 4.1E-94 T 29-03-2018 IPR026988 YaaC-like protein A616_RS23955 7bd6d572b170ac8c8f0e88696fdb50a7 421 Gene3D G3DSA:1.10.30.10 143 258 0.13 T 29-03-2018 IPR009071 High mobility group box domain A616_RS17455 3c7ae309e1d144cae1d9a91ca116a5a5 1111 Pfam PF06605 Prophage endopeptidase tail 45 496 2.2E-19 T 29-03-2018 IPR010572 Prophage tail endopeptidase A616_RS17455 3c7ae309e1d144cae1d9a91ca116a5a5 1111 Gene3D G3DSA:1.10.287.620 274 556 0.001 T 29-03-2018 A616_RS04690 2cbdfaf02b9eb47ed32c11a003fd6930 490 Pfam PF00395 S-layer homology domain 89 129 1.7E-4 T 29-03-2018 IPR001119 S-layer homology domain A616_RS17135 3496266168d9839057826f5ce443787a 220 Gene3D G3DSA:3.40.1800.10 107 190 2.2E-8 T 29-03-2018 A616_RS03775 3f292c18126112bc7f3f46a7592eeae2 203 Pfam PF00395 S-layer homology domain 140 187 2.1E-9 T 29-03-2018 IPR001119 S-layer homology domain A616_RS06945 4538936a4e616cfee8838bc9cfda30bc 473 Pfam PF04293 SpoVR like protein 5 411 2.5E-169 T 29-03-2018 IPR007390 Sporulation stage V, protein R A616_RS13230 a99ba6f15ec11ae4caa4d6de9a2483ed 58 Pfam PF10958 Protein of unknown function (DUF2759) 10 43 1.2E-5 T 29-03-2018 IPR024490 Protein of unknown function DUF2759 A616_RS10150 421b07915e3d831f9f7bc2e94f41b6c0 108 PRINTS PR01217 Proline rich extensin signature 24 41 3.1E-10 T 29-03-2018 A616_RS10150 421b07915e3d831f9f7bc2e94f41b6c0 108 PRINTS PR01217 Proline rich extensin signature 7 23 3.1E-10 T 29-03-2018 A616_RS10150 421b07915e3d831f9f7bc2e94f41b6c0 108 PRINTS PR01217 Proline rich extensin signature 43 68 3.1E-10 T 29-03-2018 A616_RS23415 d3bb0c2d97e272ab3d4dabd6987e47f6 275 Pfam PF01066 CDP-alcohol phosphatidyltransferase 56 120 1.5E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A616_RS02165 d1990b565f0a6970a357426804317911 343 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 333 3.4E-33 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A616_RS14145 819d442579cdf81f5df09db410cb6808 266 Gene3D G3DSA:3.10.180.10 1 125 2.4E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS14145 819d442579cdf81f5df09db410cb6808 266 SUPERFAMILY SSF54593 2 119 3.32E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A616_RS14980 6b80deec91363d9c4e63a813b98f33eb 1155 Pfam PF13569 Domain of unknown function (DUF4132) 881 1065 3.1E-51 T 29-03-2018 IPR025406 Domain of unknown function DUF4132 A616_RS28260 b7df8503d8a6987db9489cc422be3fd4 465 Gene3D G3DSA:2.60.40.1630 83 356 0.01 T 29-03-2018 A616_RS13110 a0ad3eb3d07305752d91fe9fa9f83122 70 Pfam PF10031 Small integral membrane protein (DUF2273) 6 52 1.6E-17 T 29-03-2018 IPR018730 Protein of unknown function DUF2273 A616_RS00945 20a35fa0a566316b089ea24fb978c818 242 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 114 207 9.1E-10 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain A616_RS13435 335a319df21b56b48e340a0de05ff3c5 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 2 111 2.0E-39 T 29-03-2018 IPR005562 SpoVA A616_RS13435 335a319df21b56b48e340a0de05ff3c5 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 1.3E-50 T 29-03-2018 IPR014204 Sporulation stage V, protein AE A616_RS02070 224fa8ad083b050f38f339512b5e170d 460 Pfam PF02447 GntP family permease 35 245 1.1E-9 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A616_RS21945 2804e0c60a912cf727de1a0bb9ee677e 185 Pfam PF08006 Protein of unknown function (DUF1700) 6 176 2.9E-13 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 A616_RS01295 2d2272f4e59a2f04c630f0beb92dc809 174 Gene3D G3DSA:3.40.50.1010 71 118 0.33 T 29-03-2018 IPR029060 PIN domain-like A616_RS01295 2d2272f4e59a2f04c630f0beb92dc809 174 Gene3D G3DSA:3.40.50.1010 5 70 0.2 T 29-03-2018 IPR029060 PIN domain-like A616_RS01295 2d2272f4e59a2f04c630f0beb92dc809 174 Pfam PF05991 YacP-like NYN domain 10 173 2.6E-54 T 29-03-2018 IPR010298 Protein of unknown function DUF901 A616_RS17900 030090fc554fb9c56cf877b7f1efb0c4 391 Pfam PF01757 Acyltransferase family 9 360 1.1E-36 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS15755 9e60e0f60f89b34c77f4fe3a694973de 220 Pfam PF00395 S-layer homology domain 171 203 2.1E-5 T 29-03-2018 IPR001119 S-layer homology domain A616_RS15755 9e60e0f60f89b34c77f4fe3a694973de 220 Pfam PF00395 S-layer homology domain 30 67 2.8E-6 T 29-03-2018 IPR001119 S-layer homology domain A616_RS21170 b0aba929362b321d499034ef138b8d3b 449 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 99 269 4.1E-38 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS21170 b0aba929362b321d499034ef138b8d3b 449 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 99 269 1.7E-32 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain A616_RS05495 6cdc333a70966321832fd5cfdfca092f 308 SUPERFAMILY SSF55729 11 304 7.27E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS05495 6cdc333a70966321832fd5cfdfca092f 308 Gene3D G3DSA:3.40.630.30 159 307 7.5E-21 T 29-03-2018 A616_RS05495 6cdc333a70966321832fd5cfdfca092f 308 Gene3D G3DSA:3.40.630.30 2 121 1.1E-5 T 29-03-2018 A616_RS05495 6cdc333a70966321832fd5cfdfca092f 308 Pfam PF00583 Acetyltransferase (GNAT) family 198 294 2.7E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 A616_RS05650 1a5e3cf246cf5e73799acb027819350c 53 Pfam PF14149 YhfH-like protein 1 37 4.2E-17 T 29-03-2018 IPR025432 YhfH-like protein A616_RS09215 9b88e91b615effc486b468e58ce6fb86 962 Pfam PF02687 FtsX-like permease family 856 948 3.2E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS09215 9b88e91b615effc486b468e58ce6fb86 962 Pfam PF02687 FtsX-like permease family 333 428 1.3E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A616_RS04290 6c64e4485c3795ce0b42f865e2962b7a 207 Pfam PF01184 GPR1/FUN34/yaaH family 5 189 1.4E-19 T 29-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 A616_RS00540 8f985f0a92095d07a81d863d03549e87 88 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 86 4.3E-19 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA A616_RS00540 8f985f0a92095d07a81d863d03549e87 88 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 87 1.5E-20 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA A616_RS18310 f37c9d77e90ec2ba6800507ecb95493f 228 Pfam PF14329 Domain of unknown function (DUF4386) 15 221 5.7E-37 T 29-03-2018 IPR025495 Protein of unknown function DUF4386 A616_RS08405 8b3a7e0de22fb9d163403eec0a346180 239 Pfam PF17294 Uncharacterised lipoprotein family 32 238 2.4E-49 T 29-03-2018 IPR035253 Putative lipoprotein, bacteria A616_RS00430 16eac0b29ac76e44d232d1e077a74fd3 142 Pfam PF14101 Domain of unknown function (DUF4275) 1 139 2.3E-64 T 29-03-2018 IPR025454 Protein of unknown function DUF4275 A616_RS24080 a7c37680457667a6c5e4d6a61a3bf336 76 Pfam PF06569 Protein of unknown function (DUF1128) 4 74 1.5E-30 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 A616_RS09825 0dfb26812e34e3eda85335fbedcd0574 173 SUPERFAMILY SSF55729 1 157 6.62E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase A616_RS09825 0dfb26812e34e3eda85335fbedcd0574 173 Gene3D G3DSA:3.40.630.30 3 161 3.2E-11 T 29-03-2018 A616_RS14935 16b4ee2a04d17f408a68fd81e330fa9c 203 Pfam PF09335 SNARE associated Golgi protein 30 160 8.1E-23 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS04990 249d1c176b0a78645be0bca0544dbd3e 243 Pfam PF02535 ZIP Zinc transporter 101 237 6.0E-13 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A616_RS14245 253865d1207f03fab8c3df942a00eb64 496 Pfam PF00474 Sodium:solute symporter family 35 428 4.1E-21 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A616_RS06620 2603bf64dd44dcd1d30626c5627a2fdf 763 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 394 718 3.5E-122 T 29-03-2018 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 A616_RS07095 e323791791011d0188cefd7a0482fab3 292 Pfam PF14005 YpjP-like protein 164 289 1.6E-33 T 29-03-2018 IPR025616 YpjP-like protein A616_RS09655 5fe46f7db6a993cd345ad5c4ff98de77 420 Pfam PF04932 O-Antigen ligase 202 345 2.5E-11 T 29-03-2018 IPR007016 O-antigen ligase-related A616_RS30035 ce2850e56aad656057ba96534c018c78 260 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 35 160 4.3E-48 T 29-03-2018 IPR014202 Sporulation stage II, protein R A616_RS30035 ce2850e56aad656057ba96534c018c78 260 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 7 165 1.6E-57 T 29-03-2018 IPR014202 Sporulation stage II, protein R A616_RS18375 181bf4559132d2d42ecfeade0ba13ebc 119 Pfam PF12788 YmaF family 20 114 2.2E-39 T 29-03-2018 IPR024307 YmaF A616_RS28450 86f65fe44d1f61045a3841ca5b0f5675 508 Pfam PF03413 Peptidase propeptide and YPEB domain 364 433 0.0046 T 29-03-2018 IPR025711 PepSY domain A616_RS24545 ae28606f183a7863221faf0a548fdb33 222 Gene3D G3DSA:3.40.1000.10 56 214 3.4E-10 T 29-03-2018 A616_RS25475 ec1f5d002ef313d3147aa63c0c678ee9 364 Pfam PF01594 AI-2E family transporter 16 329 9.5E-39 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like A616_RS19995 f1c26610378a2ba3a178541bb4ff39ad 73 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.9E-26 T 29-03-2018 IPR009384 Flagellar A616_RS20530 68d17b7cd61b70d4144fff480aab2e5b 374 Pfam PF14258 Domain of unknown function (DUF4350) 40 107 7.5E-12 T 29-03-2018 IPR025646 Domain of unknown function DUF4350 A616_RS19275 7fe04236d5dc869570e5cdb758636a2d 104 Gene3D G3DSA:3.30.2120.10 1 104 6.2E-7 T 29-03-2018 A616_RS07845 3f4dc051d3ec45937e8a751d6e53a253 304 Gene3D G3DSA:3.20.20.80 19 291 5.5E-6 T 29-03-2018 A616_RS24525 b48ffe8a9f7b558c3d8844b03fb786e4 140 Pfam PF14107 Domain of unknown function (DUF4280) 20 138 1.4E-31 T 29-03-2018 IPR025460 Protein of unknown function DUF4280 A616_RS30130 8d54eace6a31142ac013449ad13c9b47 190 Pfam PF07291 Methylamine utilisation protein MauE 4 139 1.0E-23 T 29-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 A616_RS06295 2b55f166bcc7e00fa2f541d884bc3443 130 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 11 129 3.7E-20 T 29-03-2018 IPR006524 Transcription activator, ArpU family A616_RS00485 a562c7ec937791020916ba4475c56460 219 Pfam PF09335 SNARE associated Golgi protein 31 156 1.2E-19 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS04185 09bbc6cbd9f99ace3a875c5163cb6abf 358 Pfam PF01757 Acyltransferase family 6 326 7.3E-30 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A616_RS09650 3f41f3179810d77e5b130a68d5764d03 542 SUPERFAMILY SSF69318 357 512 4.58E-7 T 29-03-2018 A616_RS09650 3f41f3179810d77e5b130a68d5764d03 542 Gene3D G3DSA:2.130.10.130 329 521 1.7E-7 T 29-03-2018 A616_RS28045 335efe9a869a26988dda954bf2dedf49 292 Gene3D G3DSA:2.60.520.10 39 128 2.3E-4 T 29-03-2018 A616_RS13240 ccd6ec59874298b3df86579a6524a773 184 Pfam PF11382 Copper transport outer membrane protein, MctB 1 113 1.5E-16 T 29-03-2018 IPR021522 Copper transporter MctB GO:0006810 A616_RS13240 ccd6ec59874298b3df86579a6524a773 184 Gene3D G3DSA:3.40.50.1980 31 130 0.0013 T 29-03-2018 A616_RS03430 122cd1bf022b031f45dd277112f33be7 311 Pfam PF00482 Type II secretion system (T2SS), protein F 166 290 2.7E-19 T 29-03-2018 IPR018076 Type II secretion system F domain A616_RS01730 5c584bf70f232ea97423358e25d41966 81 Gene3D G3DSA:1.20.1260.10 1 77 3.0E-8 T 29-03-2018 IPR012347 Ferritin-related A616_RS10120 2eac1706c97257cb6023a8fbd21d5237 288 Gene3D G3DSA:3.90.550.10 12 257 5.7E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A616_RS02760 29aef1c214719cd126df5e267a65080c 66 Pfam PF04070 Domain of unknown function (DUF378) 2 58 1.8E-25 T 29-03-2018 IPR007211 Protein of unknown function DUF378 A616_RS23170 848caacba2860f9c310f6ec99a443327 167 Pfam PF13826 Domain of unknown function (DUF4188) 17 134 2.6E-44 T 29-03-2018 IPR025444 Monooxygenase af470-like A616_RS00460 11f4fdefefe468a19c7ad74b3e662b29 88 Pfam PF02583 Metal-sensitive transcriptional repressor 7 85 3.0E-22 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 A616_RS18125 6d5b63c99e1ab23c2a4d42e08a16bf43 243 Pfam PF06889 Protein of unknown function (DUF1266) 76 235 5.7E-31 T 29-03-2018 IPR009677 Protein of unknown function DUF1266 A616_RS08300 1ed04efb6d18da214dae6761c42e1840 162 Pfam PF15583 Immunity protein 68 2 161 1.1E-54 T 29-03-2018 IPR028276 Immunity protein 68 A616_RS26700 ffa42c17fb3420e1589762afc50ad06c 178 Pfam PF05076 Suppressor of fused protein (SUFU) 30 174 4.1E-9 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 A616_RS26090 e269eee871fee0c092380d8606b497d5 133 Pfam PF13799 Domain of unknown function (DUF4183) 57 127 3.0E-19 T 29-03-2018 IPR025237 Domain of unknown function DUF4183 A616_RS06810 6da65a16d264c861dff68824b837c9fe 121 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 3 111 1.3E-35 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 A616_RS04260 1f7c0c3cbc48962de475c379d4bfcb7a 217 Pfam PF07007 Lysozyme inhibitor LprI 118 198 5.9E-10 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal A616_RS22865 0b5c163698964d2d4be12679dd38d82b 258 Pfam PF07070 SpoOM protein 4 211 5.7E-82 T 29-03-2018 IPR009776 Sporulation stage 0, protein M A616_RS09525 ddd048795e8909b947312ee84ffb2da6 205 Pfam PF09335 SNARE associated Golgi protein 31 156 1.4E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein A616_RS11855 eb3ef2a9557c0943000d0755271178bb 207 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 62 197 1.5E-7 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like A616_RS02975 892e734c3e0c48d87bc4fb62b68d0f17 745 Gene3D G3DSA:3.40.720.10 250 354 3.0E-5 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A616_RS23285 07a5a3dfa5c1b6160a6f4fc491f4207a 128 Pfam PF14107 Domain of unknown function (DUF4280) 5 122 5.5E-33 T 29-03-2018 IPR025460 Protein of unknown function DUF4280 A616_RS30235 e6b8c793d7d230eb3cab7a4215253a86 165 Pfam PF08741 YwhD family 7 164 8.8E-74 T 29-03-2018 IPR014852 Uncharacterised protein YwhD A616_RS04200 a1560cb39c046892bd1bb98fafcb265c 99 Pfam PF12728 Helix-turn-helix domain 50 98 1.6E-11 T 29-03-2018 A616_RS27550 4eb613c81fe772396877b552151e3edc 105 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 25 95 9.6E-14 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 A616_RS06350 93d073f7a5cf8a59e3252c5f7a282ffb 275 Pfam PF04233 Phage Mu protein F like protein 150 271 1.3E-11 T 29-03-2018 IPR006528 Phage head morphogenesis domain A616_RS29855 634ab12c46823532412439885c273582 169 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 161 1.1E-39 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A616_RS20580 38a15bb37729662db61140cbf5242cd5 169 Pfam PF10648 Immunoglobulin-like domain of bacterial spore germination 84 158 1.2E-17 T 29-03-2018 IPR018911 Bacterial spore germination, immunoglobulin-like domain A616_RS20450 aa1f38f66b891c848c6fa8876c624642 175 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 80 168 8.5E-26 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841