locus-tag	class	description
BP422_RS00015	COG1522	sequence-specific DNA binding
BP422_RS00020	COG1902	pentaerythritol trinitrate reductase activity
BP422_RS00045	COG0084	hydrolase, TatD family'
BP422_RS00070	COG1378	Sugar-specific transcriptional regulator TrmB
BP422_RS00105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BP422_RS00125	COG1268	BioY protein
BP422_RS00130	COG2124	cytochrome p450
BP422_RS00135	COG5002	protein histidine kinase activity
BP422_RS00140	COG0745	RESPONSE REGULATOR receiver
BP422_RS00155	COG1842	Phage shock protein A
BP422_RS00160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BP422_RS00165	COG4758	membrane
BP422_RS00170	COG4585	Histidine kinase
BP422_RS00175	COG2197	response regulator
BP422_RS00180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BP422_RS00200	COG0583	DNA-binding transcription factor activity
BP422_RS00205	COG2814	Major facilitator Superfamily
BP422_RS00210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BP422_RS00230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BP422_RS00235	COG3384	dioxygenase
BP422_RS00240	COG1595	DNA-templated transcription, initiation
BP422_RS00245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BP422_RS00255	COG1988	membrane-bound metal-dependent
BP422_RS00280	COG0840	transmembrane signaling receptor activity
BP422_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS00295	COG0456	acetyltransferase
BP422_RS00300	COG3557	Belongs to the UPF0374 family
BP422_RS00305	COG1132	(ABC) transporter
BP422_RS00310	COG2814	Major facilitator Superfamily
BP422_RS00320	COG0583	DNA-binding transcription factor activity
BP422_RS00330	COG0840	transmembrane signaling receptor activity
BP422_RS00335	COG0655	NAD(P)H dehydrogenase (quinone) activity
BP422_RS00435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BP422_RS00490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BP422_RS00495	COG2738	Putative neutral zinc metallopeptidase
BP422_RS00500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BP422_RS00510	COG4555	ABC transporter
BP422_RS00525	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BP422_RS00530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BP422_RS00535	COG0546	phosphoglycolate phosphatase activity
BP422_RS00545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BP422_RS00550	COG1363	Peptidase, m42
BP422_RS00555	COG2226	methyltransferase
BP422_RS00560	COG2096	Adenosyltransferase
BP422_RS00565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS00570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BP422_RS00575	COG0735	belongs to the Fur family
BP422_RS00580	COG3858	chitin binding
BP422_RS00675	COG2233	PERMEase
BP422_RS00685	COG0328	RNA-DNA hybrid ribonuclease activity
BP422_RS00690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BP422_RS00695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BP422_RS00715	COG0546	phosphoglycolate phosphatase activity
BP422_RS00730	COG2766	serine protein kinase
BP422_RS00735	COG2718	Belongs to the UPF0229 family
BP422_RS00775	COG2766	serine protein kinase
BP422_RS00780	COG2718	Belongs to the UPF0229 family
BP422_RS00785	COG4682	membrane
BP422_RS00790	COG0596	Alpha beta hydrolase
BP422_RS00795	COG0840	transmembrane signaling receptor activity
BP422_RS00795	COG3290	protein histidine kinase activity
BP422_RS00815	COG2801	Transposase and inactivated derivatives
BP422_RS00820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS00825	COG0765	amino acid transport
BP422_RS00830	COG1126	abc transporter atp-binding protein
BP422_RS00840	COG1695	Transcriptional regulator
BP422_RS00870	COG5001	Diguanylate cyclase
BP422_RS00870	COG3300	MHYT domain
BP422_RS00875	COG0697	spore germination
BP422_RS00880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BP422_RS00885	COG1335	isochorismatase
BP422_RS00900	COG0745	RESPONSE REGULATOR receiver
BP422_RS00905	COG5002	protein histidine kinase activity
BP422_RS00910	COG1522	sequence-specific DNA binding
BP422_RS00915	COG0436	Aminotransferase
BP422_RS00945	COG0833	amino acid
BP422_RS01025	COG0746	molybdenum cofactor guanylyltransferase activity
BP422_RS01035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BP422_RS01040	COG2223	nitrite transmembrane transporter activity
BP422_RS01055	COG0303	'Molybdopterin
BP422_RS01060	COG1763	Mo-molybdopterin cofactor biosynthetic process
BP422_RS01070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS01085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BP422_RS01095	COG1988	membrane-bound metal-dependent
BP422_RS01110	COG2814	Major facilitator Superfamily
BP422_RS01110	COG0477	Major facilitator Superfamily
BP422_RS01120	COG2259	Doxx family
BP422_RS01125	COG3973	AAA domain
BP422_RS01135	COG2363	Small membrane protein
BP422_RS01145	COG2719	SpoVR family
BP422_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
BP422_RS01165	COG0840	transmembrane signaling receptor activity
BP422_RS01195	COG0861	Integral membrane protein TerC family
BP422_RS01200	COG0583	DNA-binding transcription factor activity
BP422_RS01210	COG3181	Tripartite tricarboxylate transporter family receptor
BP422_RS01225	COG2226	methyltransferase
BP422_RS01235	COG0697	spore germination
BP422_RS01240	COG4565	transcriptional regulatory protein
BP422_RS01245	COG3290	protein histidine kinase activity
BP422_RS01260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BP422_RS01265	COG1845	cytochrome c oxidase, subunit III
BP422_RS01310	COG2367	Beta-lactamase
BP422_RS01315	COG0745	RESPONSE REGULATOR receiver
BP422_RS01330	COG2814	Major facilitator Superfamily
BP422_RS01340	COG2814	Major facilitator Superfamily
BP422_RS01350	COG1397	ADP-ribosylglycohydrolase
BP422_RS01375	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BP422_RS01400	COG0765	amino acid transport
BP422_RS01405	COG0765	amino acid transport
BP422_RS01410	COG4191	Histidine kinase
BP422_RS01415	COG0784	Response regulator, receiver
BP422_RS01445	COG0069	glutamate synthase activity
BP422_RS01450	COG0450	alkyl hydroperoxide reductase
BP422_RS01470	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BP422_RS01475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BP422_RS01485	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BP422_RS01490	COG0406	alpha-ribazole phosphatase activity
BP422_RS01495	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BP422_RS01550	COG1492	cobalamin metabolic process
BP422_RS01555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BP422_RS01560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BP422_RS01565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BP422_RS01565	COG1648	precorrin-2 dehydrogenase activity
BP422_RS01570	COG0456	acetyltransferase
BP422_RS01580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS01585	COG0475	glutathione-regulated potassium exporter activity
BP422_RS01590	COG0490	domain, Protein
BP422_RS01600	COG1301	dicarboxylic acid transport
BP422_RS01610	COG0745	RESPONSE REGULATOR receiver
BP422_RS01615	COG5002	protein histidine kinase activity
BP422_RS01620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BP422_RS01625	COG3290	protein histidine kinase activity
BP422_RS01640	COG4565	transcriptional regulatory protein
BP422_RS01645	COG3829	transcription factor binding
BP422_RS01650	COG1619	proteins homologs of microcin C7 resistance protein MccF
BP422_RS01710	COG0783	Belongs to the Dps family
BP422_RS01715	COG1072	(Pantothenic acid kinase))
BP422_RS01720	COG1683	Conserved Protein
BP422_RS01730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BP422_RS01735	COG0583	DNA-binding transcription factor activity
BP422_RS01765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BP422_RS01775	COG0180	Tryptophanyl-tRNA synthetase
BP422_RS01825	COG0748	coenzyme F420 binding
BP422_RS01830	COG1120	ATPase activity
BP422_RS01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS01855	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BP422_RS01880	COG0402	S-adenosylhomocysteine deaminase activity
BP422_RS01885	COG1737	Transcriptional regulator
BP422_RS01890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS01895	COG1653	transport
BP422_RS01900	COG1175	transmembrane transport
BP422_RS01905	COG0395	ABC-type sugar transport system, permease component
BP422_RS01910	COG2971	BadF BadG BcrA BcrD
BP422_RS01915	COG4191	Histidine kinase
BP422_RS01925	COG3706	GGDEF domain
BP422_RS01930	COG1757	Na H antiporter
BP422_RS01945	COG0450	alkyl hydroperoxide reductase
BP422_RS01965	COG1215	transferase activity, transferring glycosyl groups
BP422_RS01970	COG0745	RESPONSE REGULATOR receiver
BP422_RS01980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BP422_RS01990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BP422_RS02015	COG0189	ligase activity
BP422_RS02020	COG0189	ligase activity
BP422_RS02025	COG0189	ligase activity
BP422_RS02030	COG0189	ligase activity
BP422_RS02035	COG4399	Belongs to the UPF0754 family
BP422_RS02040	COG4109	DRTGG domain
BP422_RS02050	COG0640	Transcriptional regulator
BP422_RS02060	COG0587	DNA-directed DNA polymerase activity
BP422_RS02065	COG0281	malic enzyme
BP422_RS02070	COG2186	Transcriptional regulator
BP422_RS02080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BP422_RS02085	COG0825	malonyl-CoA metabolic process
BP422_RS02090	COG0205	6-phosphofructokinase activity
BP422_RS02100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BP422_RS02110	COG0824	Thioesterase
BP422_RS02120	COG0628	permease
BP422_RS02125	COG0372	Belongs to the citrate synthase family
BP422_RS02130	COG0538	isocitrate dehydrogenase activity
BP422_RS02135	COG0039	L-malate dehydrogenase activity
BP422_RS02140	COG0745	RESPONSE REGULATOR receiver
BP422_RS02145	COG5002	protein histidine kinase activity
BP422_RS02150	COG0704	Plays a role in the regulation of phosphate uptake
BP422_RS02160	COG2720	vancomycin resistance protein
BP422_RS02180	COG1846	Transcriptional regulator
BP422_RS02185	COG1566	PFAM secretion protein HlyD family protein
BP422_RS02195	COG2814	Major facilitator Superfamily
BP422_RS02205	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS02205	COG2247	cell wall binding repeat
BP422_RS02210	COG2861	carbohydrate metabolic process
BP422_RS02215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BP422_RS02215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BP422_RS02220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BP422_RS02225	COG0237	dephospho-CoA kinase activity
BP422_RS02235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BP422_RS02245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BP422_RS02255	COG1484	DNA-dependent DNA replication
BP422_RS02280	COG3279	Response regulator of the LytR AlgR family
BP422_RS02285	COG3275	phosphorelay sensor kinase activity
BP422_RS02290	COG0477	Major facilitator Superfamily
BP422_RS02310	COG2249	NAD(P)H dehydrogenase (quinone) activity
BP422_RS02315	COG2207	Transcriptional regulator
BP422_RS02315	COG4753	response regulator
BP422_RS02335	COG1846	Transcriptional regulator
BP422_RS02340	COG2814	Major facilitator Superfamily
BP422_RS02355	COG1309	transcriptional regulator
BP422_RS02365	COG1902	pentaerythritol trinitrate reductase activity
BP422_RS02370	COG1522	sequence-specific DNA binding
BP422_RS02380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS02385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS02395	COG5002	protein histidine kinase activity
BP422_RS02410	COG2132	Multicopper oxidase
BP422_RS02420	COG1063	alcohol dehydrogenase
BP422_RS02425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BP422_RS02425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BP422_RS02435	COG1307	EDD domain protein, DegV family
BP422_RS02460	COG2311	Membrane
BP422_RS02465	COG1361	Conserved repeat domain
BP422_RS02500	COG1129	ABC transporter
BP422_RS02520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS02525	COG1063	alcohol dehydrogenase
BP422_RS02535	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BP422_RS02580	COG0326	Molecular chaperone. Has ATPase activity
BP422_RS02595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BP422_RS02605	COG1113	amino acid transport
BP422_RS02610	COG1121	(ABC) transporter
BP422_RS02615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BP422_RS02620	COG0803	Belongs to the bacterial solute-binding protein 9 family
BP422_RS02625	COG0217	transcriptional regulatory protein
BP422_RS02635	COG0789	Transcriptional regulator
BP422_RS02645	COG0217	transcriptional regulatory protein
BP422_RS02655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS02660	COG1595	DNA-templated transcription, initiation
BP422_RS02675	COG1695	Transcriptional regulator
BP422_RS02680	COG0772	Belongs to the SEDS family
BP422_RS02690	COG1132	(ABC) transporter
BP422_RS02695	COG1132	(ABC) transporter
BP422_RS02700	COG2226	methyltransferase
BP422_RS02705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS02725	COG0330	HflC and HflK could
BP422_RS02735	COG0450	alkyl hydroperoxide reductase
BP422_RS02745	COG3428	Bacterial PH domain
BP422_RS02750	COG0346	lactoylglutathione lyase activity
BP422_RS02760	COG4196	transglutaminase domain protein
BP422_RS02765	COG1643	Atp-dependent helicase
BP422_RS02770	COG0778	Nitroreductase
BP422_RS02775	COG0745	RESPONSE REGULATOR receiver
BP422_RS02780	COG5002	protein histidine kinase activity
BP422_RS02790	COG1136	(ABC) transporter
BP422_RS02795	COG1136	(ABC) transporter
BP422_RS02795	COG0577	efflux transmembrane transporter activity
BP422_RS02820	COG1970	mechanosensitive ion channel activity
BP422_RS02845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BP422_RS02850	COG0747	negative chemotaxis
BP422_RS02860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS02870	COG0444	Belongs to the ABC transporter superfamily
BP422_RS02875	COG4608	Belongs to the ABC transporter superfamily
BP422_RS02880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BP422_RS02885	COG0277	FAD linked oxidase domain protein
BP422_RS02890	COG0247	lactate metabolic process
BP422_RS02895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BP422_RS02915	COG1051	belongs to the nudix hydrolase family
BP422_RS02945	COG0456	acetyltransferase
BP422_RS02965	COG2814	Major facilitator Superfamily
BP422_RS02970	COG2304	oxidoreductase activity
BP422_RS02980	COG0673	inositol 2-dehydrogenase activity
BP422_RS02985	COG1309	transcriptional regulator
BP422_RS02995	COG0180	Tryptophanyl-tRNA synthetase
BP422_RS03000	COG0583	DNA-binding transcription factor activity
BP422_RS03055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BP422_RS03060	COG4565	transcriptional regulatory protein
BP422_RS03065	COG2972	Histidine kinase
BP422_RS03070	COG4608	Belongs to the ABC transporter superfamily
BP422_RS03075	COG0444	Belongs to the ABC transporter superfamily
BP422_RS03080	COG0601	transmembrane transport
BP422_RS03085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS03090	COG0402	S-adenosylhomocysteine deaminase activity
BP422_RS03100	COG0402	S-adenosylhomocysteine deaminase activity
BP422_RS03105	COG0583	DNA-binding transcription factor activity
BP422_RS03110	COG0477	Major facilitator Superfamily
BP422_RS03115	COG0583	DNA-binding transcription factor activity
BP422_RS03120	COG2814	Major facilitator Superfamily
BP422_RS03150	COG1280	lysine exporter protein (LysE YggA)
BP422_RS03155	COG2808	Putative FMN-binding domain
BP422_RS03160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS03165	COG0402	S-adenosylhomocysteine deaminase activity
BP422_RS03170	COG0402	S-adenosylhomocysteine deaminase activity
BP422_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS03180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BP422_RS03190	COG0747	negative chemotaxis
BP422_RS03210	COG0747	negative chemotaxis
BP422_RS03215	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BP422_RS03220	COG0477	Major facilitator Superfamily
BP422_RS03250	COG3773	Cell wall hydrolase
BP422_RS03260	COG0318	PFAM AMP-dependent synthetase and ligase
BP422_RS03265	COG1960	acyl-CoA dehydrogenase activity
BP422_RS03280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BP422_RS03290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BP422_RS03300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BP422_RS03305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BP422_RS03310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BP422_RS03315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BP422_RS03330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BP422_RS03345	COG0175	sulfate reduction
BP422_RS03350	COG2046	Belongs to the sulfate adenylyltransferase family
BP422_RS03355	COG0028	Belongs to the TPP enzyme family
BP422_RS03360	COG0440	acetolactate synthase activity
BP422_RS03365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BP422_RS03370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BP422_RS03375	COG0473	3-isopropylmalate dehydrogenase activity
BP422_RS03380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BP422_RS03385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS03405	COG0586	Pfam SNARE associated Golgi protein
BP422_RS03415	COG3844	kynureninase activity
BP422_RS03420	COG0697	spore germination
BP422_RS03425	COG0814	amino acid
BP422_RS03435	COG0814	amino acid
BP422_RS03445	COG0569	domain protein
BP422_RS03450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BP422_RS03460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BP422_RS03470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BP422_RS03480	COG1193	negative regulation of DNA recombination
BP422_RS03485	COG3766	membrane
BP422_RS03505	COG1278	Cold shock
BP422_RS03515	COG2362	D-Aminopeptidase
BP422_RS03520	COG0438	transferase activity, transferring glycosyl groups
BP422_RS03555	COG2244	polysaccharide biosynthetic process
BP422_RS03575	COG0183	Belongs to the thiolase family
BP422_RS03580	COG1316	TRANSCRIPTIONal
BP422_RS03585	COG0318	PFAM AMP-dependent synthetase and ligase
BP422_RS03590	COG1309	transcriptional regulator
BP422_RS03595	COG1024	Enoyl-CoA hydratase
BP422_RS03600	COG2086	electron transfer activity
BP422_RS03605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BP422_RS03620	COG3118	belongs to the thioredoxin family
BP422_RS03655	COG0322	excinuclease ABC activity
BP422_RS03670	COG2009	succinate dehydrogenase
BP422_RS03675	COG1053	succinate dehydrogenase
BP422_RS03680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BP422_RS03695	COG1846	Transcriptional regulator
BP422_RS03715	COG0601	transmembrane transport
BP422_RS03730	COG2197	response regulator
BP422_RS03745	COG2350	Protein conserved in bacteria
BP422_RS03775	COG2197	response regulator
BP422_RS03825	COG1175	transmembrane transport
BP422_RS03830	COG0395	ABC-type sugar transport system, permease component
BP422_RS03835	COG0673	inositol 2-dehydrogenase activity
BP422_RS03855	COG1940	carbohydrate kinase activity
BP422_RS03870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BP422_RS03880	COG1473	amidohydrolase
BP422_RS03885	COG3290	protein histidine kinase activity
BP422_RS03890	COG2814	Major facilitator Superfamily
BP422_RS03900	COG1378	Sugar-specific transcriptional regulator TrmB
BP422_RS03915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BP422_RS03950	COG0463	Glycosyl transferase, family 2
BP422_RS03960	COG2340	Cysteine-rich secretory protein family
BP422_RS03970	COG1216	Glycosyl transferase, family 2
BP422_RS03975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BP422_RS03985	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BP422_RS03985	COG0662	Cupin 2, conserved barrel domain protein
BP422_RS04020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS04025	COG1216	Glycosyl transferase, family 2
BP422_RS04025	COG1442	glycosyl transferase family 8
BP422_RS04045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BP422_RS04050	COG0562	UDP-galactopyranose mutase
BP422_RS04055	COG0463	Glycosyl transferase, family 2
BP422_RS04055	COG1216	Glycosyl transferase, family 2
BP422_RS04085	COG3290	protein histidine kinase activity
BP422_RS04085	COG3829	transcription factor binding
BP422_RS04090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS04095	COG0601	transmembrane transport
BP422_RS04100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS04115	COG0583	DNA-binding transcription factor activity
BP422_RS04120	COG0384	phenazine biosynthesis protein PhzF
BP422_RS04130	COG3209	COG3209 Rhs family protein
BP422_RS04200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BP422_RS04205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BP422_RS04220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BP422_RS04225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BP422_RS04230	COG0622	Phosphoesterase
BP422_RS04235	COG0544	peptidyl-prolyl cis-trans isomerase activity
BP422_RS04240	COG0740	serine-type endopeptidase activity
BP422_RS04245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BP422_RS04250	COG0470	DNA polymerase III
BP422_RS04250	COG1067	ATP-dependent peptidase activity
BP422_RS04260	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BP422_RS04265	COG3291	Pkd domain containing protein
BP422_RS04265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BP422_RS04275	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BP422_RS04280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BP422_RS04285	COG0181	hydroxymethylbilane synthase activity
BP422_RS04295	COG0113	porphobilinogen synthase activity
BP422_RS04320	COG2267	carboxylic ester hydrolase activity
BP422_RS04325	COG0737	Belongs to the 5'-nucleotidase family
BP422_RS04330	COG1695	Transcriptional regulator
BP422_RS04345	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BP422_RS04350	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BP422_RS04355	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BP422_RS04360	COG1388	LysM domain
BP422_RS04395	COG0525	valine-tRNA ligase activity
BP422_RS04400	COG0285	dihydrofolate synthase activity
BP422_RS04405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BP422_RS04415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BP422_RS04435	COG0424	maF-like protein
BP422_RS04440	COG2003	Belongs to the UPF0758 family
BP422_RS04445	COG1077	Cell shape determining protein MreB Mrl
BP422_RS04450	COG1792	Involved in formation and maintenance of cell shape
BP422_RS04455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BP422_RS04460	COG0768	penicillin binding
BP422_RS04465	COG0850	regulation of cytokinetic process
BP422_RS04470	COG2894	cell division
BP422_RS04475	COG0772	Belongs to the SEDS family
BP422_RS04480	COG1278	Cold shock
BP422_RS04490	COG1994	Peptidase M50
BP422_RS04500	COG1530	ribonuclease E activity
BP422_RS04505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BP422_RS04515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BP422_RS04525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BP422_RS04540	COG1252	NADH dehydrogenase
BP422_RS04545	COG4492	Belongs to the UPF0735 family
BP422_RS04550	COG0460	homoserine dehydrogenase
BP422_RS04555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BP422_RS04560	COG0083	homoserine kinase activity
BP422_RS04565	COG0077	Prephenate dehydratase
BP422_RS04570	COG1388	LysM domain
BP422_RS04580	COG0737	Belongs to the 5'-nucleotidase family
BP422_RS04600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BP422_RS04605	COG0632	four-way junction helicase activity
BP422_RS04610	COG2255	four-way junction helicase activity
BP422_RS04620	COG2385	sporulation resulting in formation of a cellular spore
BP422_RS04625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BP422_RS04635	COG1862	Preprotein translocase
BP422_RS04645	COG0598	Magnesium transport protein CorA
BP422_RS04650	COG2323	membrane
BP422_RS04655	COG2244	polysaccharide biosynthetic process
BP422_RS04665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BP422_RS04665	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BP422_RS04670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BP422_RS04670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BP422_RS04675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BP422_RS04675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BP422_RS04680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BP422_RS04685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BP422_RS04690	COG1490	D-aminoacyl-tRNA deacylase activity
BP422_RS04700	COG2318	DinB family
BP422_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS04710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BP422_RS04715	COG0124	histidyl-tRNA synthetase
BP422_RS04720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BP422_RS04730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BP422_RS04740	COG1959	2 iron, 2 sulfur cluster binding
BP422_RS04745	COG1104	cysteine desulfurase activity
BP422_RS04750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BP422_RS04770	COG0861	Integral membrane protein TerC family
BP422_RS04775	COG0628	permease
BP422_RS04785	COG4472	Bacterial protein of unknown function (DUF965)
BP422_RS04790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BP422_RS04795	COG3906	Belongs to the UPF0473 family
BP422_RS04800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BP422_RS04805	COG4122	O-methyltransferase activity
BP422_RS04815	COG0768	penicillin binding
BP422_RS04845	COG0443	Heat shock 70 kDa protein
BP422_RS04930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BP422_RS05000	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BP422_RS05015	COG3209	COG3209 Rhs family protein
BP422_RS05060	COG1329	Transcriptional regulator
BP422_RS05075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BP422_RS05095	COG3336	cytochrome c oxidase
BP422_RS05100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS05110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BP422_RS05120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BP422_RS05125	COG0488	(ABC) transporter
BP422_RS05135	COG1376	ErfK ybiS ycfS ynhG family protein
BP422_RS05155	COG1413	lyase activity
BP422_RS05160	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BP422_RS05170	COG4166	transmembrane transport
BP422_RS05175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BP422_RS05180	COG0438	transferase activity, transferring glycosyl groups
BP422_RS05185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS05190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BP422_RS05210	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BP422_RS05215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BP422_RS05220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BP422_RS05225	COG1534	Rna-binding protein
BP422_RS05230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BP422_RS05235	COG1713	HD superfamily hydrolase involved in NAD metabolism
BP422_RS05240	COG0799	negative regulation of ribosome biogenesis
BP422_RS05245	COG2226	methyltransferase
BP422_RS05250	COG0495	leucyl-tRNA aminoacylation
BP422_RS05255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BP422_RS05260	COG1596	polysaccharide export
BP422_RS05260	COG1555	photosystem II stabilization
BP422_RS05265	COG0367	asparagine synthase
BP422_RS05270	COG0658	competence protein
BP422_RS05270	COG2333	competence protein COMEC
BP422_RS05285	COG1466	dna polymerase III delta subunit
BP422_RS05290	COG0268	Binds directly to 16S ribosomal RNA
BP422_RS05300	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS05310	COG0444	Belongs to the ABC transporter superfamily
BP422_RS05315	COG4608	Belongs to the ABC transporter superfamily
BP422_RS05320	COG0747	negative chemotaxis
BP422_RS05325	COG0601	transmembrane transport
BP422_RS05330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS05340	COG0006	proline dipeptidase activity
BP422_RS05350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS05355	COG1120	ATPase activity
BP422_RS05360	COG2226	methyltransferase
BP422_RS05365	COG1595	DNA-templated transcription, initiation
BP422_RS05380	COG0481	GTPase activity
BP422_RS05385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BP422_RS05390	COG1420	regulation of RNA biosynthetic process
BP422_RS05400	COG0443	Heat shock 70 kDa protein
BP422_RS05405	COG0484	heat shock protein binding
BP422_RS05410	COG2264	protein methyltransferase activity
BP422_RS05415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BP422_RS05420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BP422_RS05430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BP422_RS05440	COG1346	cytolysis
BP422_RS05445	COG1283	sodium-dependent phosphate transmembrane transporter activity
BP422_RS05470	COG1181	Belongs to the D-alanine--D-alanine ligase family
BP422_RS05490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS05500	COG1082	Xylose isomerase domain protein TIM barrel
BP422_RS05510	COG0406	alpha-ribazole phosphatase activity
BP422_RS05515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BP422_RS05520	COG0537	adenosine 5'-monophosphoramidase activity
BP422_RS05525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BP422_RS05530	COG1610	YqeY-like protein
BP422_RS05535	COG1030	water channel activity
BP422_RS05540	COG4864	UPF0365 protein
BP422_RS05565	COG1702	phosphate starvation-inducible protein PhoH
BP422_RS05570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BP422_RS05575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BP422_RS05580	COG0295	cytidine deaminase activity
BP422_RS05585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BP422_RS05595	COG1381	Involved in DNA repair and RecF pathway recombination
BP422_RS05600	COG0752	glycyl-tRNA synthetase alpha subunit
BP422_RS05605	COG0751	glycine-tRNA ligase activity
BP422_RS05610	COG0517	IMP dehydrogenase activity
BP422_RS05615	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BP422_RS05620	COG0358	DNA primase activity
BP422_RS05625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BP422_RS05635	COG1960	acyl-CoA dehydrogenase activity
BP422_RS05645	COG2384	SAM-dependent methyltransferase
BP422_RS05650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BP422_RS05660	COG3409	Peptidoglycan-binding domain 1 protein
BP422_RS05660	COG0793	Belongs to the peptidase S41A family
BP422_RS05725	COG1242	4 iron, 4 sulfur cluster binding
BP422_RS05730	COG0584	glycerophosphoryl diester phosphodiesterase
BP422_RS05740	COG0456	acetyltransferase
BP422_RS05750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BP422_RS05755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BP422_RS05760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BP422_RS05765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS05770	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS05780	COG0318	PFAM AMP-dependent synthetase and ligase
BP422_RS05785	COG3876	Protein conserved in bacteria
BP422_RS05805	COG1309	transcriptional regulator
BP422_RS05845	COG0745	RESPONSE REGULATOR receiver
BP422_RS05860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BP422_RS05875	COG0561	phosphatase activity
BP422_RS05880	COG3842	ATPase activity
BP422_RS05885	COG3835	regulator
BP422_RS05890	COG1408	metallophosphoesterase
BP422_RS05895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BP422_RS05905	COG2072	flavoprotein involved in K transport
BP422_RS05915	COG0701	Predicted permease
BP422_RS05970	COG2197	response regulator
BP422_RS05975	COG3850	Histidine kinase
BP422_RS05980	COG0351	phosphomethylpyrimidine kinase
BP422_RS05990	COG1595	DNA-templated transcription, initiation
BP422_RS06005	COG1428	Deoxynucleoside kinase
BP422_RS06010	COG1428	Deoxynucleoside kinase
BP422_RS06030	COG2154	pterin-4-alpha-carbinolamine dehydratase
BP422_RS06045	COG1607	acyl-coa hydrolase
BP422_RS06050	COG0667	Aldo Keto reductase
BP422_RS06060	COG3011	Protein conserved in bacteria
BP422_RS06065	COG2986	histidine ammonia-lyase
BP422_RS06085	COG4294	response to UV
BP422_RS06090	COG3300	MHYT domain
BP422_RS06090	COG5001	Diguanylate cyclase
BP422_RS06115	COG1119	ATPase activity
BP422_RS06145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BP422_RS06160	COG0477	Major facilitator Superfamily
BP422_RS06170	COG0535	radical SAM domain protein
BP422_RS06185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BP422_RS06200	COG2373	Large extracellular alpha-helical protein
BP422_RS06205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BP422_RS06210	COG1846	Transcriptional regulator
BP422_RS06255	COG0840	transmembrane signaling receptor activity
BP422_RS06265	COG0243	molybdopterin cofactor binding
BP422_RS06270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BP422_RS06280	COG0367	asparagine synthase
BP422_RS06285	COG3275	phosphorelay sensor kinase activity
BP422_RS06290	COG3279	Response regulator of the LytR AlgR family
BP422_RS06295	COG3162	membrane
BP422_RS06300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BP422_RS06305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BP422_RS06340	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BP422_RS06360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BP422_RS06365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BP422_RS06370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS06375	COG0765	amino acid transport
BP422_RS06380	COG1126	abc transporter atp-binding protein
BP422_RS06385	COG0183	Belongs to the thiolase family
BP422_RS06395	COG0018	arginyl-trna synthetase
BP422_RS06410	COG1595	DNA-templated transcription, initiation
BP422_RS06430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BP422_RS06430	COG0646	methionine synthase
BP422_RS06445	COG0300	oxidoreductase activity
BP422_RS06450	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BP422_RS06455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BP422_RS06460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS06465	COG0006	proline dipeptidase activity
BP422_RS06470	COG0006	proline dipeptidase activity
BP422_RS06500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS06505	COG3739	integral membrane protein
BP422_RS06510	COG2819	hydrolase of the alpha beta superfamily
BP422_RS06520	COG2207	Transcriptional regulator
BP422_RS06520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS06560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BP422_RS06565	COG1116	anion transmembrane transporter activity
BP422_RS06570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BP422_RS06575	COG1234	tRNA 3'-trailer cleavage
BP422_RS06600	COG1404	Belongs to the peptidase S8 family
BP422_RS06610	COG1671	Belongs to the UPF0178 family
BP422_RS06615	COG0671	phosphoesterase, PA-phosphatase related
BP422_RS06620	COG0583	DNA-binding transcription factor activity
BP422_RS06625	COG0477	Major facilitator Superfamily
BP422_RS06630	COG0833	amino acid
BP422_RS06635	COG3829	transcription factor binding
BP422_RS06640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BP422_RS06650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BP422_RS06655	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BP422_RS06660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BP422_RS06665	COG2066	Belongs to the glutaminase family
BP422_RS06670	COG4838	Belongs to the UPF0358 family
BP422_RS06675	COG0733	neurotransmitter:sodium symporter activity
BP422_RS06680	COG0387	Pfam Sodium calcium exchanger
BP422_RS06695	COG0028	Belongs to the TPP enzyme family
BP422_RS06705	COG0772	Belongs to the SEDS family
BP422_RS06715	COG0517	IMP dehydrogenase activity
BP422_RS06720	COG2226	methyltransferase
BP422_RS06730	COG1525	nuclease
BP422_RS06745	COG3300	MHYT domain
BP422_RS06745	COG5001	Diguanylate cyclase
BP422_RS06780	COG3546	catalase activity
BP422_RS06790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BP422_RS06810	COG3679	Belongs to the UPF0342 family
BP422_RS06825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BP422_RS06830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BP422_RS06835	COG4149	molybdate abc transporter
BP422_RS06840	COG0725	ABC transporter, periplasmic molybdate-binding protein
BP422_RS06845	COG1910	domain protein
BP422_RS06855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BP422_RS06880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BP422_RS06890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BP422_RS06895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BP422_RS06905	COG0095	Lipoate-protein ligase
BP422_RS06925	COG0431	NADPH-dependent FMN reductase
BP422_RS06930	COG1321	iron dependent repressor
BP422_RS06935	COG1752	Esterase of the alpha-beta hydrolase superfamily
BP422_RS06945	COG3872	metal-dependent enzyme
BP422_RS06955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BP422_RS06960	COG0006	proline dipeptidase activity
BP422_RS06965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BP422_RS06980	COG1595	DNA-templated transcription, initiation
BP422_RS06990	COG2707	UPF0756 membrane protein
BP422_RS07000	COG1809	phosphosulfolactate synthase activity
BP422_RS07015	COG3854	ATPases associated with a variety of cellular activities
BP422_RS07055	COG0511	ligase activity, forming carbon-carbon bonds
BP422_RS07060	COG0439	Biotin carboxylase
BP422_RS07065	COG1302	Protein conserved in bacteria
BP422_RS07080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BP422_RS07085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BP422_RS07090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BP422_RS07095	COG1570	exodeoxyribonuclease VII activity
BP422_RS07105	COG0142	geranyltranstransferase activity
BP422_RS07115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BP422_RS07120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BP422_RS07125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BP422_RS07130	COG1438	arginine binding
BP422_RS07135	COG0497	DNA recombination
BP422_RS07140	COG0750	zinc metalloprotease
BP422_RS07165	COG0745	RESPONSE REGULATOR receiver
BP422_RS07195	COG0288	reversible hydration of carbon dioxide
BP422_RS07200	COG1408	metallophosphoesterase
BP422_RS07210	COG2226	methyltransferase
BP422_RS07220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BP422_RS07255	COG3829	transcription factor binding
BP422_RS07255	COG3290	protein histidine kinase activity
BP422_RS07260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BP422_RS07265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BP422_RS07270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BP422_RS07275	COG0022	dehydrogenase e1 component
BP422_RS07280	COG0508	dehydrogenase complex catalyzes the overall conversion of
BP422_RS07290	COG0346	lactoylglutathione lyase activity
BP422_RS07295	COG2195	Cleaves the N-terminal amino acid of tripeptides
BP422_RS07310	COG0494	nUDIX hydrolase
BP422_RS07315	COG1379	DNA repair
BP422_RS07320	COG1300	Membrane
BP422_RS07325	COG0735	belongs to the Fur family
BP422_RS07335	COG4974	Belongs to the 'phage' integrase family
BP422_RS07340	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BP422_RS07350	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BP422_RS07355	COG1522	sequence-specific DNA binding
BP422_RS07360	COG4166	transmembrane transport
BP422_RS07365	COG0601	transmembrane transport
BP422_RS07370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS07375	COG0444	Belongs to the ABC transporter superfamily
BP422_RS07380	COG4608	Belongs to the ABC transporter superfamily
BP422_RS07385	COG0840	transmembrane signaling receptor activity
BP422_RS07390	COG1686	Belongs to the peptidase S11 family
BP422_RS07400	COG2172	sigma factor antagonist activity
BP422_RS07425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BP422_RS07440	COG0697	spore germination
BP422_RS07450	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BP422_RS07455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BP422_RS07460	COG1994	Peptidase M50
BP422_RS07465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BP422_RS07470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BP422_RS07475	COG1686	Belongs to the peptidase S11 family
BP422_RS07480	COG2715	membrane protein required for spore maturation
BP422_RS07485	COG0700	Nucleoside recognition
BP422_RS07490	COG1187	pseudouridine synthase activity
BP422_RS07495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS07500	COG1333	cytochrome c biogenesis protein
BP422_RS07505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BP422_RS07510	COG0745	RESPONSE REGULATOR receiver
BP422_RS07515	COG5002	protein histidine kinase activity
BP422_RS07530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BP422_RS07540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BP422_RS07550	COG1141	Ferredoxin
BP422_RS07585	COG4862	establishment of competence for transformation
BP422_RS07590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BP422_RS07595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BP422_RS07605	COG0252	asparaginase activity
BP422_RS07610	COG2339	peptidase activity
BP422_RS07620	COG2959	enzyme of heme biosynthesis
BP422_RS07635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BP422_RS07645	COG0539	negative regulation of cytoplasmic translation
BP422_RS07650	COG1304	FMN binding
BP422_RS07670	COG1160	GTP binding
BP422_RS07675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BP422_RS07680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BP422_RS07715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BP422_RS07720	COG0776	regulation of translation
BP422_RS07725	COG0302	gtp cyclohydrolase
BP422_RS07735	COG0741	lytic transglycosylase activity
BP422_RS07750	COG0142	geranyltranstransferase activity
BP422_RS07760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BP422_RS07765	COG0163	prenyltransferase activity
BP422_RS07770	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BP422_RS07780	COG0105	UTP biosynthetic process
BP422_RS07785	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BP422_RS07790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BP422_RS07795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BP422_RS07810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BP422_RS07815	COG0134	indole-3-glycerol-phosphate synthase activity
BP422_RS07820	COG0135	phosphoribosylanthranilate isomerase activity
BP422_RS07825	COG0133	tryptophan synthase activity
BP422_RS07830	COG0159	tryptophan synthase activity
BP422_RS07835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BP422_RS07840	COG0287	Prephenate dehydrogenase
BP422_RS07845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BP422_RS07855	COG1595	DNA-templated transcription, initiation
BP422_RS07890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BP422_RS07910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BP422_RS07920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BP422_RS07925	COG1803	Methylglyoxal synthase
BP422_RS07930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BP422_RS07935	COG0438	transferase activity, transferring glycosyl groups
BP422_RS07940	COG0617	tRNA 3'-terminal CCA addition
BP422_RS07950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BP422_RS07955	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BP422_RS07960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BP422_RS07970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BP422_RS07970	COG1199	ATP-dependent helicase activity
BP422_RS07980	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BP422_RS07985	COG0402	S-adenosylhomocysteine deaminase activity
BP422_RS08005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BP422_RS08015	COG0017	Asparaginyl-tRNA synthetase
BP422_RS08020	COG3935	DnaD domain protein
BP422_RS08040	COG0463	Glycosyl transferase, family 2
BP422_RS08045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS08050	COG0438	transferase activity, transferring glycosyl groups
BP422_RS08055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BP422_RS08060	COG1164	Oligoendopeptidase f
BP422_RS08065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BP422_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS08080	COG1666	GTP binding
BP422_RS08090	COG0318	PFAM AMP-dependent synthetase and ligase
BP422_RS08100	COG0066	3-isopropylmalate dehydratase activity
BP422_RS08105	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BP422_RS08110	COG0583	DNA-binding transcription factor activity
BP422_RS08115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS08120	COG0564	pseudouridine synthase activity
BP422_RS08135	COG0456	acetyltransferase
BP422_RS08140	COG2816	NAD+ diphosphatase activity
BP422_RS08145	COG3048	D-serine ammonia-lyase activity
BP422_RS08150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BP422_RS08160	COG0154	amidase activity
BP422_RS08165	COG1054	Belongs to the UPF0176 family
BP422_RS08170	COG0756	dUTP diphosphatase activity
BP422_RS08180	COG2072	flavoprotein involved in K transport
BP422_RS08185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BP422_RS08190	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BP422_RS08195	COG4208	sulfate ABC transporter
BP422_RS08205	COG0488	(ABC) transporter
BP422_RS08215	COG2508	Transcriptional regulator
BP422_RS08225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BP422_RS08240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BP422_RS08240	COG3153	acetyltransferase
BP422_RS08245	COG0456	acetyltransferase
BP422_RS08260	COG3829	transcription factor binding
BP422_RS08260	COG3290	protein histidine kinase activity
BP422_RS08265	COG1122	ATPase activity
BP422_RS08275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BP422_RS08280	COG4684	Psort location CytoplasmicMembrane, score
BP422_RS08285	COG3191	aminopeptidase activity
BP422_RS08290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS08305	COG1388	LysM domain
BP422_RS08305	COG3103	Sh3 type 3 domain protein
BP422_RS08305	COG0791	NLP P60 protein
BP422_RS08330	COG2720	vancomycin resistance protein
BP422_RS08345	COG0791	NLP P60 protein
BP422_RS08350	COG1309	transcriptional regulator
BP422_RS08355	COG0318	PFAM AMP-dependent synthetase and ligase
BP422_RS08360	COG2030	dehydratase
BP422_RS08365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BP422_RS08395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BP422_RS08400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BP422_RS08420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS08450	COG0069	glutamate synthase activity
BP422_RS08460	COG3858	chitin binding
BP422_RS08465	COG0492	ferredoxin-NADP+ reductase activity
BP422_RS08470	COG0537	adenosine 5'-monophosphoramidase activity
BP422_RS08480	COG1959	2 iron, 2 sulfur cluster binding
BP422_RS08515	COG2378	regulation of single-species biofilm formation
BP422_RS08520	COG3708	Transcriptional regulator
BP422_RS08530	COG0745	RESPONSE REGULATOR receiver
BP422_RS08535	COG5002	protein histidine kinase activity
BP422_RS08545	COG0662	Cupin 2, conserved barrel domain protein
BP422_RS08565	COG0747	negative chemotaxis
BP422_RS08575	COG5002	protein histidine kinase activity
BP422_RS08580	COG1280	lysine exporter protein (LysE YggA)
BP422_RS08585	COG2814	Major facilitator Superfamily
BP422_RS08595	COG1733	regulation of RNA biosynthetic process
BP422_RS08610	COG0659	secondary active sulfate transmembrane transporter activity
BP422_RS08615	COG3191	aminopeptidase activity
BP422_RS08620	COG1132	(ABC) transporter
BP422_RS08630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BP422_RS08645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BP422_RS08650	COG1414	Transcriptional regulator
BP422_RS08655	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BP422_RS08660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BP422_RS08670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BP422_RS08695	COG2309	aminopeptidase activity
BP422_RS08700	COG1164	Oligoendopeptidase f
BP422_RS08705	COG3695	enzyme binding
BP422_RS08715	COG1199	ATP-dependent helicase activity
BP422_RS08720	COG2132	Multicopper oxidase
BP422_RS08730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BP422_RS08730	COG2755	lipolytic protein G-D-S-L family
BP422_RS08735	COG0697	spore germination
BP422_RS08740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS08755	COG0601	transmembrane transport
BP422_RS08760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS08765	COG0444	Belongs to the ABC transporter superfamily
BP422_RS08770	COG4608	Belongs to the ABC transporter superfamily
BP422_RS08775	COG4166	transmembrane transport
BP422_RS08780	COG0823	Involved in the tonB-independent uptake of proteins
BP422_RS08780	COG1506	peptidase
BP422_RS08785	COG4946	Tricorn protease homolog
BP422_RS08785	COG1506	peptidase
BP422_RS08785	COG0823	Involved in the tonB-independent uptake of proteins
BP422_RS08790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS08795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BP422_RS08795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BP422_RS08805	COG1876	peptidase activity
BP422_RS08810	COG1309	transcriptional regulator
BP422_RS08815	COG0511	ligase activity, forming carbon-carbon bonds
BP422_RS08820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BP422_RS08820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BP422_RS08825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BP422_RS08825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BP422_RS08835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BP422_RS08840	COG0511	ligase activity, forming carbon-carbon bonds
BP422_RS08845	COG0439	Biotin carboxylase
BP422_RS08890	COG0109	protoheme IX farnesyltransferase activity
BP422_RS08905	COG0747	negative chemotaxis
BP422_RS08915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS08925	COG4608	Belongs to the ABC transporter superfamily
BP422_RS08970	COG0586	Pfam SNARE associated Golgi protein
BP422_RS08995	COG3483	tryptophan 2,3-dioxygenase activity
BP422_RS09000	COG0714	Associated with various cellular activities
BP422_RS09010	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BP422_RS09045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BP422_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS09070	COG0583	DNA-binding transcription factor activity
BP422_RS09075	COG0070	glutamate synthase
BP422_RS09075	COG0067	glutamate synthase
BP422_RS09075	COG0069	glutamate synthase activity
BP422_RS09090	COG0346	lactoylglutathione lyase activity
BP422_RS09105	COG1737	Transcriptional regulator
BP422_RS09110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BP422_RS09130	COG1115	amino acid carrier protein
BP422_RS09135	COG2066	Belongs to the glutaminase family
BP422_RS09140	COG4191	Histidine kinase
BP422_RS09145	COG0784	Response regulator, receiver
BP422_RS09150	COG0596	Alpha beta hydrolase
BP422_RS09155	COG1309	transcriptional regulator
BP422_RS09160	COG1802	Transcriptional regulator
BP422_RS09185	COG1082	Xylose isomerase domain protein TIM barrel
BP422_RS09195	COG1653	transport
BP422_RS09220	COG1309	transcriptional regulator
BP422_RS09225	COG0583	DNA-binding transcription factor activity
BP422_RS09235	COG2070	2-Nitropropane dioxygenase
BP422_RS09260	COG3604	Transcriptional regulator
BP422_RS09285	COG0346	lactoylglutathione lyase activity
BP422_RS09300	COG2249	NAD(P)H dehydrogenase (quinone) activity
BP422_RS09305	COG1733	regulation of RNA biosynthetic process
BP422_RS09320	COG1388	LysM domain
BP422_RS09325	COG1510	regulation of RNA biosynthetic process
BP422_RS09345	COG0488	(ABC) transporter
BP422_RS09350	COG2404	hydrolase activity, acting on ester bonds
BP422_RS09360	COG3832	glyoxalase III activity
BP422_RS09365	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BP422_RS09410	COG2814	Major facilitator Superfamily
BP422_RS09435	COG1132	(ABC) transporter
BP422_RS09455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS09460	COG2362	D-Aminopeptidase
BP422_RS09470	COG0791	NLP P60 protein
BP422_RS09475	COG0745	RESPONSE REGULATOR receiver
BP422_RS09480	COG5002	protein histidine kinase activity
BP422_RS09495	COG2258	MOSC domain
BP422_RS09500	COG0662	Cupin 2, conserved barrel domain protein
BP422_RS09505	COG4191	Histidine kinase
BP422_RS09510	COG2364	Membrane
BP422_RS09515	COG2814	Major facilitator Superfamily
BP422_RS09535	COG0747	negative chemotaxis
BP422_RS09550	COG0444	Belongs to the ABC transporter superfamily
BP422_RS09555	COG1124	(ABC) transporter
BP422_RS09570	COG2197	response regulator
BP422_RS09585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BP422_RS09595	COG0601	transmembrane transport
BP422_RS09600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS09605	COG0444	Belongs to the ABC transporter superfamily
BP422_RS09610	COG4608	Belongs to the ABC transporter superfamily
BP422_RS09620	COG0006	proline dipeptidase activity
BP422_RS09635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS09645	COG1396	sequence-specific DNA binding
BP422_RS09655	COG0747	negative chemotaxis
BP422_RS09660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS09665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS09695	COG2195	Cleaves the N-terminal amino acid of tripeptides
BP422_RS09705	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BP422_RS09725	COG0745	RESPONSE REGULATOR receiver
BP422_RS09730	COG5002	protein histidine kinase activity
BP422_RS09730	COG3850	Histidine kinase
BP422_RS09735	COG2205	protein histidine kinase activity
BP422_RS09750	COG0640	Transcriptional regulator
BP422_RS09755	COG5658	integral membrane protein
BP422_RS09765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BP422_RS09770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BP422_RS09780	COG0656	L-ascorbic acid biosynthetic process
BP422_RS09790	COG4555	ABC transporter
BP422_RS09820	COG1131	(ABC) transporter
BP422_RS09835	COG0393	Putative heavy-metal-binding
BP422_RS09870	COG1595	DNA-templated transcription, initiation
BP422_RS09895	COG0667	Aldo Keto reductase
BP422_RS09900	COG1113	amino acid transport
BP422_RS09905	COG0697	spore germination
BP422_RS09910	COG0531	amino acid
BP422_RS09935	COG2368	4-hydroxyphenylacetate
BP422_RS09960	COG3971	2-oxopent-4-enoate hydratase activity
BP422_RS09965	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BP422_RS09970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BP422_RS09980	COG1309	transcriptional regulator
BP422_RS09990	COG0191	fructose-bisphosphate aldolase activity
BP422_RS09995	COG0667	Aldo Keto reductase
BP422_RS10040	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS10045	COG0833	amino acid
BP422_RS10050	COG2040	homocysteine
BP422_RS10075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BP422_RS10090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS10100	COG4607	ABC-type enterochelin transport system periplasmic component
BP422_RS10125	COG2801	Transposase and inactivated derivatives
BP422_RS10135	COG0662	Cupin 2, conserved barrel domain protein
BP422_RS10215	COG1250	3-hydroxyacyl-CoA dehydrogenase
BP422_RS10230	COG4106	trans-aconitate 2-methyltransferase activity
BP422_RS10235	COG1960	acyl-CoA dehydrogenase activity
BP422_RS10265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS10280	COG4221	oxidoreductase activity
BP422_RS10280	COG3321	synthase
BP422_RS10280	COG0300	oxidoreductase activity
BP422_RS10280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS10295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BP422_RS10300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BP422_RS10310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS10340	COG0546	phosphoglycolate phosphatase activity
BP422_RS10360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS10360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS10360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS10360	COG3321	synthase
BP422_RS10365	COG3321	synthase
BP422_RS10365	COG4221	oxidoreductase activity
BP422_RS10365	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS10365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS10375	COG3321	synthase
BP422_RS10375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS10375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS10375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS10380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS10380	COG3321	synthase
BP422_RS10380	COG4221	oxidoreductase activity
BP422_RS10380	COG0300	oxidoreductase activity
BP422_RS10390	COG0673	inositol 2-dehydrogenase activity
BP422_RS10425	COG0250	Participates in transcription elongation, termination and antitermination
BP422_RS10440	COG4221	oxidoreductase activity
BP422_RS10460	COG4974	Belongs to the 'phage' integrase family
BP422_RS10470	COG0813	purine-nucleoside phosphorylase activity
BP422_RS10485	COG1686	Belongs to the peptidase S11 family
BP422_RS10490	COG2357	RelA SpoT domain protein
BP422_RS10520	COG0714	Associated with various cellular activities
BP422_RS10525	COG3069	C4-dicarboxylate transmembrane transporter activity
BP422_RS10530	COG3949	Membrane
BP422_RS10570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS10575	COG0444	Belongs to the ABC transporter superfamily
BP422_RS10580	COG4608	Belongs to the ABC transporter superfamily
BP422_RS10615	COG1673	EVE domain
BP422_RS10630	COG0583	DNA-binding transcription factor activity
BP422_RS10635	COG1942	4-Oxalocrotonate Tautomerase
BP422_RS10655	COG2207	Transcriptional regulator
BP422_RS10655	COG1917	Cupin 2, conserved barrel domain protein
BP422_RS10660	COG0506	proline dehydrogenase activity
BP422_RS10670	COG1620	l-lactate permease
BP422_RS10675	COG2186	Transcriptional regulator
BP422_RS10680	COG0247	lactate metabolic process
BP422_RS10685	COG1139	Iron-sulfur cluster binding protein
BP422_RS10690	COG1556	Lactate utilization protein
BP422_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS10700	COG0583	DNA-binding transcription factor activity
BP422_RS10740	COG2249	NAD(P)H dehydrogenase (quinone) activity
BP422_RS10785	COG0753	catalase activity
BP422_RS10800	COG1278	Cold shock
BP422_RS10810	COG2340	Cysteine-rich secretory protein family
BP422_RS10820	COG0242	peptide deformylase activity
BP422_RS10830	COG0697	spore germination
BP422_RS10840	COG3361	conserved protein (COG2071)
BP422_RS10845	COG0069	glutamate synthase activity
BP422_RS10845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BP422_RS10850	COG2311	Membrane
BP422_RS10855	COG1114	Component of the transport system for branched-chain amino acids
BP422_RS10865	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BP422_RS10870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BP422_RS10875	COG2027	D-alanyl-D-alanine carboxypeptidase
BP422_RS10900	COG0745	RESPONSE REGULATOR receiver
BP422_RS10905	COG2205	protein histidine kinase activity
BP422_RS10910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BP422_RS10915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BP422_RS10920	COG1116	anion transmembrane transporter activity
BP422_RS10925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BP422_RS10930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS10935	COG2022	thiamine diphosphate biosynthetic process
BP422_RS10940	COG2104	thiamine diphosphate biosynthetic process
BP422_RS10950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BP422_RS10960	COG1388	LysM domain
BP422_RS10960	COG3858	chitin binding
BP422_RS10965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS10970	COG0515	serine threonine protein kinase
BP422_RS10975	COG2084	Dehydrogenase
BP422_RS11025	COG2814	Major facilitator Superfamily
BP422_RS11030	COG1733	regulation of RNA biosynthetic process
BP422_RS11035	COG2249	NAD(P)H dehydrogenase (quinone) activity
BP422_RS11040	COG0456	acetyltransferase
BP422_RS11045	COG0318	PFAM AMP-dependent synthetase and ligase
BP422_RS11055	COG2843	Capsule synthesis protein
BP422_RS11070	COG0583	DNA-binding transcription factor activity
BP422_RS11105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BP422_RS11110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BP422_RS11115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BP422_RS11120	COG1780	Probably involved in ribonucleotide reductase function
BP422_RS11125	COG2819	hydrolase of the alpha beta superfamily
BP422_RS11140	COG0482	sulfurtransferase activity
BP422_RS11165	COG0584	glycerophosphoryl diester phosphodiesterase
BP422_RS11190	COG0385	Bile acid
BP422_RS11205	COG4122	O-methyltransferase activity
BP422_RS11255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BP422_RS11295	COG3964	amidohydrolase
BP422_RS11310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BP422_RS11315	COG1011	Hydrolase
BP422_RS11330	COG0577	efflux transmembrane transporter activity
BP422_RS11330	COG1136	(ABC) transporter
BP422_RS11335	COG4591	ABC-type transport system involved in lipoprotein release permease component
BP422_RS11335	COG1136	(ABC) transporter
BP422_RS11375	COG4989	oxidoreductase activity
BP422_RS11395	COG1475	DNA binding
BP422_RS11405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BP422_RS11495	COG3093	addiction module antidote protein HigA
BP422_RS11505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS11510	COG0785	Cytochrome C biogenesis protein
BP422_RS11535	COG4585	Histidine kinase
BP422_RS11540	COG2197	response regulator
BP422_RS11550	COG3852	Histidine kinase
BP422_RS11565	COG0352	thiamine-phosphate diphosphorylase activity
BP422_RS11570	COG0352	thiamine-phosphate diphosphorylase activity
BP422_RS11605	COG4565	transcriptional regulatory protein
BP422_RS11610	COG3290	protein histidine kinase activity
BP422_RS11615	COG1953	Uracil, thiamine, allantoin
BP422_RS11640	COG0493	'glutamate synthase
BP422_RS11665	COG1611	Belongs to the LOG family
BP422_RS11670	COG1694	Mazg nucleotide pyrophosphohydrolase
BP422_RS11675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BP422_RS11680	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS11685	COG3835	regulator
BP422_RS11695	COG0464	growth
BP422_RS11700	COG2814	Major facilitator Superfamily
BP422_RS11705	COG1846	Transcriptional regulator
BP422_RS11725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BP422_RS11745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BP422_RS11750	COG0778	Nitroreductase
BP422_RS11760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BP422_RS11765	COG0187	DNA topoisomerase II activity
BP422_RS11790	COG1131	(ABC) transporter
BP422_RS11805	COG1595	DNA-templated transcription, initiation
BP422_RS11810	COG0626	cystathionine gamma-synthase activity
BP422_RS11815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BP422_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS11835	COG2707	UPF0756 membrane protein
BP422_RS11860	COG4848	Belongs to the UPF0354 family
BP422_RS11890	COG0488	(ABC) transporter
BP422_RS11920	COG0508	dehydrogenase complex catalyzes the overall conversion of
BP422_RS11925	COG0022	dehydrogenase e1 component
BP422_RS11945	COG4166	transmembrane transport
BP422_RS11955	COG0316	Belongs to the HesB IscA family
BP422_RS11960	COG3973	AAA domain
BP422_RS11965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BP422_RS11970	COG4224	UPF0291 protein
BP422_RS11975	COG1388	LysM domain
BP422_RS11980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BP422_RS11995	COG2135	peptidase activity
BP422_RS12045	COG0798	PFAM Bile acid sodium symporter
BP422_RS12050	COG0346	lactoylglutathione lyase activity
BP422_RS12055	COG0640	Transcriptional regulator
BP422_RS12060	COG2135	peptidase activity
BP422_RS12105	COG5566	PFAM Mor transcription activator
BP422_RS12120	COG0640	Transcriptional regulator
BP422_RS12170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BP422_RS12190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS12195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BP422_RS12200	COG2890	protein-(glutamine-N5) methyltransferase activity
BP422_RS12245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS12265	COG1705	Flagellar rod assembly protein muramidase FlgJ
BP422_RS12290	COG3299	homolog of phage Mu protein gp47
BP422_RS12425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BP422_RS12520	COG1395	domain, Protein
BP422_RS12540	COG0582	viral genome integration into host DNA
BP422_RS12545	COG0174	glutamine synthetase
BP422_RS12550	COG0789	Transcriptional regulator
BP422_RS12555	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BP422_RS12560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BP422_RS12575	COG0464	growth
BP422_RS12585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BP422_RS12590	COG1846	Transcriptional regulator
BP422_RS12595	COG2814	Major facilitator Superfamily
BP422_RS12600	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BP422_RS12605	COG1923	regulation of RNA biosynthetic process
BP422_RS12610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BP422_RS12615	COG2521	methyltransferase
BP422_RS12615	COG2136	Putative SAM-dependent methyltransferase
BP422_RS12625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BP422_RS12630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BP422_RS12645	COG4550	Control of competence regulator ComK, YlbF/YmcA
BP422_RS12655	COG3693	PFAM glycoside hydrolase, family 10
BP422_RS12660	COG0095	Lipoate-protein ligase
BP422_RS12670	COG0517	IMP dehydrogenase activity
BP422_RS12680	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BP422_RS12685	COG1234	tRNA 3'-trailer cleavage
BP422_RS12690	COG3949	Membrane
BP422_RS12695	COG1013	pyruvate-flavodoxin oxidoreductase activity
BP422_RS12700	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BP422_RS12700	COG0674	pyruvate-flavodoxin oxidoreductase activity
BP422_RS12710	COG2359	stage V sporulation protein S
BP422_RS12715	COG1692	metallophosphoesterase
BP422_RS12725	COG2137	regulation of response to DNA damage stimulus
BP422_RS12730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BP422_RS12735	COG0513	Belongs to the DEAD box helicase family
BP422_RS12740	COG1058	Belongs to the CinA family
BP422_RS12740	COG1546	Belongs to the CinA family
BP422_RS12750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BP422_RS12755	COG1426	Protein conserved in bacteria
BP422_RS12770	COG0300	oxidoreductase activity
BP422_RS12775	COG0612	Peptidase, M16
BP422_RS12780	COG0612	Peptidase, M16
BP422_RS12790	COG1079	Belongs to the binding-protein-dependent transport system permease family
BP422_RS12795	COG4603	Belongs to the binding-protein-dependent transport system permease family
BP422_RS12800	COG3845	ABC transporter
BP422_RS12805	COG1744	ABC transporter substrate-binding protein PnrA-like
BP422_RS12810	COG2188	Transcriptional regulator
BP422_RS12815	COG1674	ftsk spoiiie
BP422_RS12815	COG4980	gas vesicle protein
BP422_RS12825	COG0740	serine-type endopeptidase activity
BP422_RS12830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BP422_RS12835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BP422_RS12840	COG0527	aspartate kinase activity
BP422_RS12845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BP422_RS12850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BP422_RS12855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BP422_RS12865	COG0612	Peptidase, M16
BP422_RS12870	COG0726	polysaccharide deacetylase
BP422_RS12875	COG1185	polyribonucleotide nucleotidyltransferase activity
BP422_RS12880	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BP422_RS12885	COG0196	riboflavin kinase activity
BP422_RS12890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BP422_RS12895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BP422_RS12900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BP422_RS12910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BP422_RS12910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BP422_RS12915	COG1358	cellular component organization or biogenesis
BP422_RS12925	COG0195	Participates in both transcription termination and antitermination
BP422_RS12930	COG0779	Required for maturation of 30S ribosomal subunits
BP422_RS12935	COG2176	DNA-directed DNA polymerase activity
BP422_RS12940	COG0442	prolyl-tRNA aminoacylation
BP422_RS12945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BP422_RS12950	COG0750	zinc metalloprotease
BP422_RS12955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BP422_RS12960	COG4589	Belongs to the CDS family
BP422_RS12970	COG0233	cytoplasmic translational termination
BP422_RS12975	COG0528	UMP kinase activity
BP422_RS12980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BP422_RS12985	COG0052	Belongs to the universal ribosomal protein uS2 family
BP422_RS13010	COG1191	sigma factor activity
BP422_RS13020	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BP422_RS13025	COG1776	CheC inhibitor of MCP methylation
BP422_RS13030	COG0835	chemotaxis
BP422_RS13035	COG2198	Histidine kinase
BP422_RS13035	COG0643	Histidine kinase
BP422_RS13040	COG2201	protein-glutamate methylesterase activity
BP422_RS13045	COG0455	bacterial-type flagellum organization
BP422_RS13050	COG1419	protein localization to endoplasmic reticulum
BP422_RS13055	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BP422_RS13060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BP422_RS13065	COG1684	flagellar biosynthetic protein fliR
BP422_RS13070	COG1987	bacterial-type flagellum assembly
BP422_RS13075	COG1338	Plays a role in the flagellum-specific transport system
BP422_RS13080	COG3190	flagellar
BP422_RS13085	COG2201	protein-glutamate methylesterase activity
BP422_RS13090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BP422_RS13090	COG1776	CheC inhibitor of MCP methylation
BP422_RS13095	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BP422_RS13110	COG4786	Flagellar basal body rod
BP422_RS13135	COG1157	protein secretion by the type III secretion system
BP422_RS13145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BP422_RS13150	COG1766	The M ring may be actively involved in energy transduction
BP422_RS13155	COG1677	Flagellar hook-basal body complex protein FliE
BP422_RS13160	COG1558	bacterial-type flagellum-dependent cell motility
BP422_RS13165	COG1815	bacterial-type flagellum-dependent cell motility
BP422_RS13170	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BP422_RS13175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BP422_RS13180	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BP422_RS13185	COG4974	Belongs to the 'phage' integrase family
BP422_RS13190	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BP422_RS13195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BP422_RS13200	COG0758	DNA mediated transformation
BP422_RS13205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BP422_RS13210	COG0045	succinate-CoA ligase (ADP-forming) activity
BP422_RS13230	COG0393	Putative heavy-metal-binding
BP422_RS13235	COG5001	Diguanylate cyclase
BP422_RS13245	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BP422_RS13330	COG0606	chelatase, subunit chli
BP422_RS13610	COG0305	Participates in initiation and elongation during chromosome replication
BP422_RS13620	COG3935	DnaD domain protein
BP422_RS13665	COG1396	sequence-specific DNA binding
BP422_RS13700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BP422_RS13705	COG0606	chelatase, subunit chli
BP422_RS13715	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BP422_RS13735	COG3541	Predicted nucleotidyltransferase
BP422_RS13750	COG2257	FlhB HrpN YscU SpaS Family
BP422_RS13760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BP422_RS13770	COG0681	Belongs to the peptidase S26 family
BP422_RS13775	COG0335	large ribosomal subunit rRNA binding
BP422_RS13780	COG0336	Belongs to the RNA methyltransferase TrmD family
BP422_RS13785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BP422_RS13795	COG1837	Belongs to the UPF0109 family
BP422_RS13800	COG0228	four-way junction DNA binding
BP422_RS13805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BP422_RS13810	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BP422_RS13815	COG0552	protein localization to endoplasmic reticulum
BP422_RS13820	COG1196	nuclear chromosome segregation
BP422_RS13825	COG0571	ribonuclease III activity
BP422_RS13830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BP422_RS13835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS13845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BP422_RS13850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BP422_RS13855	COG0416	fatty acid biosynthetic process
BP422_RS13860	COG1349	DNA-binding transcription factor activity
BP422_RS13865	COG4555	ABC transporter
BP422_RS13880	COG1349	DNA-binding transcription factor activity
BP422_RS13885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BP422_RS13895	COG3480	Lon protease (S16) C-terminal proteolytic domain
BP422_RS13900	COG1752	Esterase of the alpha-beta hydrolase superfamily
BP422_RS13905	COG3314	Sporulation integral membrane protein YlbJ
BP422_RS13910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BP422_RS13915	COG0742	ribosomal rna small subunit methyltransferase
BP422_RS13920	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BP422_RS13925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BP422_RS13930	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BP422_RS13940	COG1793	dna ligase
BP422_RS13960	COG0697	spore germination
BP422_RS13965	COG1793	dna ligase
BP422_RS13965	COG3285	dna ligase
BP422_RS13980	COG0306	phosphate transporter
BP422_RS13990	COG2203	Gaf domain
BP422_RS13990	COG2199	diguanylate cyclase activity
BP422_RS13995	COG3424	synthase
BP422_RS14000	COG1755	Isoprenylcysteine carboxyl methyltransferase
BP422_RS14025	COG1846	Transcriptional regulator
BP422_RS14030	COG0681	Belongs to the peptidase S26 family
BP422_RS14035	COG1876	peptidase activity
BP422_RS14040	COG0405	Gamma-glutamyltransferase
BP422_RS14045	COG4632	Exopolysaccharide biosynthesis protein
BP422_RS14045	COG5434	Belongs to the glycosyl hydrolase 28 family
BP422_RS14070	COG0714	Associated with various cellular activities
BP422_RS14095	COG0438	transferase activity, transferring glycosyl groups
BP422_RS14100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BP422_RS14105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BP422_RS14120	COG1027	Aspartate ammonia-lyase
BP422_RS14130	COG5522	Integral membrane protein (intg_mem_TP0381)
BP422_RS14135	COG0583	DNA-binding transcription factor activity
BP422_RS14150	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BP422_RS14155	COG0477	Major facilitator Superfamily
BP422_RS14160	COG1132	(ABC) transporter
BP422_RS14180	COG4990	cell redox homeostasis
BP422_RS14235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BP422_RS14240	COG3708	Transcriptional regulator
BP422_RS14240	COG2207	Transcriptional regulator
BP422_RS14260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BP422_RS14265	COG1760	l-serine dehydratase
BP422_RS14270	COG1760	l-serine dehydratase
BP422_RS14280	COG1307	EDD domain protein, DegV family
BP422_RS14285	COG1461	Dihydroxyacetone kinase
BP422_RS14290	COG1302	Protein conserved in bacteria
BP422_RS14295	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BP422_RS14305	COG3859	Proton-coupled thiamine transporter YuaJ
BP422_RS14310	COG1126	abc transporter atp-binding protein
BP422_RS14315	COG0765	amino acid transport
BP422_RS14320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS14330	COG1714	RDD family
BP422_RS14340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BP422_RS14345	COG1162	GTPase activity
BP422_RS14350	COG2815	serine threonine protein kinase
BP422_RS14350	COG0515	serine threonine protein kinase
BP422_RS14355	COG0631	protein serine/threonine phosphatase activity
BP422_RS14360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BP422_RS14365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BP422_RS14365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BP422_RS14370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BP422_RS14375	COG0242	peptide deformylase activity
BP422_RS14380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BP422_RS14385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BP422_RS14390	COG1758	RNA polymerase activity
BP422_RS14395	COG0194	GDP metabolic process
BP422_RS14400	COG2052	Domain of unknown function (DUF370)
BP422_RS14405	COG1561	YicC-like family, N-terminal region
BP422_RS14410	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BP422_RS14430	COG1024	Enoyl-CoA hydratase
BP422_RS14435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BP422_RS14455	COG1547	Domain of unknown function (DUF309)
BP422_RS14475	COG4846	Membrane protein involved in cytochrome C biogenesis
BP422_RS14480	COG0494	nUDIX hydrolase
BP422_RS14490	COG2843	Capsule synthesis protein
BP422_RS14495	COG0460	homoserine dehydrogenase
BP422_RS14505	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BP422_RS14510	COG0673	inositol 2-dehydrogenase activity
BP422_RS14515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BP422_RS14525	COG1222	aaa ATPase
BP422_RS14550	COG0640	Transcriptional regulator
BP422_RS14565	COG0284	orotidine-5'-phosphate decarboxylase activity
BP422_RS14570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BP422_RS14580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BP422_RS14585	COG0540	Belongs to the ATCase OTCase family
BP422_RS14595	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BP422_RS14610	COG0564	pseudouridine synthase activity
BP422_RS14615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BP422_RS14620	COG2112	serine threonine protein kinase
BP422_RS14630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BP422_RS14640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BP422_RS14675	COG1842	Phage shock protein A
BP422_RS14680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BP422_RS14680	COG0551	DNA topoisomerase type I activity
BP422_RS14690	COG1657	PFAM Prenyltransferase squalene oxidase
BP422_RS14730	COG3848	Pyruvate phosphate dikinase
BP422_RS14730	COG0574	Belongs to the PEP-utilizing enzyme family
BP422_RS14740	COG1316	TRANSCRIPTIONal
BP422_RS14745	COG0492	ferredoxin-NADP+ reductase activity
BP422_RS14755	COG2814	Major facilitator Superfamily
BP422_RS14760	COG4948	Mandelate Racemase Muconate Lactonizing
BP422_RS14765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BP422_RS14770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BP422_RS14775	COG3599	regulation of cell shape
BP422_RS14780	COG2302	S4 RNA-binding domain
BP422_RS14785	COG0762	integral membrane protein
BP422_RS14790	COG1799	cell septum assembly
BP422_RS14795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BP422_RS14800	COG1496	oxidoreductase activity
BP422_RS14805	COG1873	PFAM PRC-barrel domain
BP422_RS14810	COG1191	sigma factor activity
BP422_RS14815	COG1191	sigma factor activity
BP422_RS14825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BP422_RS14830	COG0849	cell division
BP422_RS14835	COG3856	small basic protein
BP422_RS14850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BP422_RS14855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BP422_RS14860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BP422_RS14865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BP422_RS14870	COG0772	Belongs to the SEDS family
BP422_RS14875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BP422_RS14880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BP422_RS14890	COG0768	penicillin binding
BP422_RS14895	COG0768	penicillin binding
BP422_RS14905	COG0275	rRNA processing
BP422_RS14910	COG2001	Belongs to the MraZ family
BP422_RS14915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BP422_RS14920	COG0583	DNA-binding transcription factor activity
BP422_RS14930	COG2911	Protein conserved in bacteria
BP422_RS14930	COG1361	Conserved repeat domain
BP422_RS14930	COG3266	domain, Protein
BP422_RS14935	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BP422_RS14950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BP422_RS14955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BP422_RS14960	COG1024	Enoyl-CoA hydratase
BP422_RS14965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BP422_RS14970	COG0511	ligase activity, forming carbon-carbon bonds
BP422_RS14975	COG0439	Biotin carboxylase
BP422_RS14980	COG0454	-acetyltransferase
BP422_RS14990	COG1024	Enoyl-CoA hydratase
BP422_RS14995	COG1393	Belongs to the ArsC family
BP422_RS15020	COG2843	Capsule synthesis protein
BP422_RS15025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS15050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BP422_RS15060	COG0626	cystathionine gamma-synthase activity
BP422_RS15065	COG0626	cystathionine gamma-synthase activity
BP422_RS15095	COG0386	Belongs to the glutathione peroxidase family
BP422_RS15100	COG1217	gtp-binding protein TYPA
BP422_RS15110	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BP422_RS15140	COG4493	Belongs to the UPF0637 family
BP422_RS15150	COG1982	Orn Lys Arg decarboxylase major
BP422_RS15155	COG0167	dihydroorotate dehydrogenase activity
BP422_RS15170	COG2267	carboxylic ester hydrolase activity
BP422_RS15190	COG1705	Flagellar rod assembly protein muramidase FlgJ
BP422_RS15205	COG1473	amidohydrolase
BP422_RS15210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BP422_RS15215	COG2171	N-acyltransferase activity
BP422_RS15220	COG0716	FMN binding
BP422_RS15230	COG2217	Heavy metal translocating P-type atpase
BP422_RS15245	COG4106	trans-aconitate 2-methyltransferase activity
BP422_RS15260	COG0577	efflux transmembrane transporter activity
BP422_RS15265	COG1136	(ABC) transporter
BP422_RS15265	COG0577	efflux transmembrane transporter activity
BP422_RS15270	COG0351	phosphomethylpyrimidine kinase
BP422_RS15275	COG2962	Rard protein
BP422_RS15330	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BP422_RS15355	COG4991	sh3 domain protein
BP422_RS15355	COG3103	Sh3 type 3 domain protein
BP422_RS15355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS15365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BP422_RS15370	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BP422_RS15375	COG1120	ATPase activity
BP422_RS15380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS15385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS15390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS15400	COG0789	Transcriptional regulator
BP422_RS15405	COG1227	inorganic diphosphatase activity
BP422_RS15415	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS15445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BP422_RS15455	COG2801	Transposase and inactivated derivatives
BP422_RS15460	COG0655	NAD(P)H dehydrogenase (quinone) activity
BP422_RS15470	COG0346	lactoylglutathione lyase activity
BP422_RS15480	COG0583	DNA-binding transcription factor activity
BP422_RS15485	COG2388	GCN5-related N-acetyl-transferase
BP422_RS15495	COG0400	carboxylic ester hydrolase activity
BP422_RS15500	COG0346	lactoylglutathione lyase activity
BP422_RS15505	COG0583	DNA-binding transcription factor activity
BP422_RS15535	COG1335	isochorismatase
BP422_RS15540	COG0783	Belongs to the Dps family
BP422_RS15550	COG1335	isochorismatase
BP422_RS15555	COG2267	carboxylic ester hydrolase activity
BP422_RS15560	COG4753	response regulator
BP422_RS15560	COG2207	Transcriptional regulator
BP422_RS15575	COG0583	DNA-binding transcription factor activity
BP422_RS15580	COG0583	DNA-binding transcription factor activity
BP422_RS15600	COG0316	Belongs to the HesB IscA family
BP422_RS15610	COG1193	negative regulation of DNA recombination
BP422_RS15630	COG1231	oxidoreductase activity
BP422_RS15635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS15645	COG0697	spore germination
BP422_RS15650	COG0640	Transcriptional regulator
BP422_RS15670	COG0786	glutamate:sodium symporter activity
BP422_RS15680	COG0583	DNA-binding transcription factor activity
BP422_RS15700	COG0367	asparagine synthase
BP422_RS15710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS15710	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS15710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS15710	COG3321	synthase
BP422_RS15710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS15715	COG3321	synthase
BP422_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS15715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS15715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS15715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS15720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS15720	COG3321	synthase
BP422_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS15720	COG4221	oxidoreductase activity
BP422_RS15725	COG4221	oxidoreductase activity
BP422_RS15725	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS15725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS15725	COG3321	synthase
BP422_RS15730	COG3321	synthase
BP422_RS15730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS15730	COG4221	oxidoreductase activity
BP422_RS15730	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS15740	COG2267	carboxylic ester hydrolase activity
BP422_RS15745	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BP422_RS15745	COG2070	2-Nitropropane dioxygenase
BP422_RS15755	COG0250	Participates in transcription elongation, termination and antitermination
BP422_RS15875	COG0596	Alpha beta hydrolase
BP422_RS15875	COG2945	thiolester hydrolase activity
BP422_RS15880	COG0582	viral genome integration into host DNA
BP422_RS15920	COG0739	heme binding
BP422_RS15940	COG3299	homolog of phage Mu protein gp47
BP422_RS16100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BP422_RS16100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BP422_RS16125	COG2002	toxin-antitoxin pair type II binding
BP422_RS16170	COG0582	viral genome integration into host DNA
BP422_RS16185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BP422_RS16195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BP422_RS16210	COG1309	transcriptional regulator
BP422_RS16235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS16245	COG1253	flavin adenine dinucleotide binding
BP422_RS16250	COG0210	DNA helicase
BP422_RS16275	COG0861	Integral membrane protein TerC family
BP422_RS16295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BP422_RS16310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BP422_RS16320	COG4533	DNA binding
BP422_RS16325	COG0477	Major facilitator Superfamily
BP422_RS16325	COG2814	Major facilitator Superfamily
BP422_RS16330	COG1116	anion transmembrane transporter activity
BP422_RS16330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BP422_RS16335	COG4120	Belongs to the binding-protein-dependent transport system permease family
BP422_RS16350	COG1253	flavin adenine dinucleotide binding
BP422_RS16360	COG1595	DNA-templated transcription, initiation
BP422_RS16375	COG2801	Transposase and inactivated derivatives
BP422_RS16395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BP422_RS16400	COG1131	(ABC) transporter
BP422_RS16410	COG2211	Major facilitator Superfamily
BP422_RS16415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS16425	COG0446	pyridine nucleotide-disulphide oxidoreductase
BP422_RS16425	COG1902	pentaerythritol trinitrate reductase activity
BP422_RS16440	COG1316	TRANSCRIPTIONal
BP422_RS16450	COG2223	nitrite transmembrane transporter activity
BP422_RS16455	COG0653	protein targeting
BP422_RS16475	COG0577	efflux transmembrane transporter activity
BP422_RS16480	COG1136	(ABC) transporter
BP422_RS16485	COG3481	metal-dependent phosphohydrolase, HD sub domain
BP422_RS16495	COG0586	Pfam SNARE associated Golgi protein
BP422_RS16515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BP422_RS16520	COG0024	Methionine aminopeptidase
BP422_RS16525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BP422_RS16530	COG1309	transcriptional regulator
BP422_RS16545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BP422_RS16550	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BP422_RS16555	COG0179	Fumarylacetoacetate (FAA) hydrolase
BP422_RS16560	COG0564	pseudouridine synthase activity
BP422_RS16570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS16580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BP422_RS16595	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BP422_RS16605	COG3874	Sporulation protein YtfJ
BP422_RS16615	COG3584	3D domain protein
BP422_RS16615	COG1388	LysM domain
BP422_RS16630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BP422_RS16640	COG2323	membrane
BP422_RS16655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BP422_RS16660	COG0726	polysaccharide deacetylase
BP422_RS16665	COG0861	Integral membrane protein TerC family
BP422_RS16670	COG4191	Histidine kinase
BP422_RS16770	COG0179	Fumarylacetoacetate (FAA) hydrolase
BP422_RS16775	COG0301	tRNA thio-modification
BP422_RS16780	COG1104	cysteine desulfurase activity
BP422_RS16785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BP422_RS16800	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BP422_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS16835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS16840	COG4948	Mandelate Racemase Muconate Lactonizing
BP422_RS16845	COG4608	Belongs to the ABC transporter superfamily
BP422_RS16850	COG0444	Belongs to the ABC transporter superfamily
BP422_RS16855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS16865	COG0747	negative chemotaxis
BP422_RS16880	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BP422_RS16890	COG4326	sporulation control protein
BP422_RS16930	COG2081	HI0933 family
BP422_RS16940	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BP422_RS16960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS16965	COG2203	Gaf domain
BP422_RS16965	COG2199	diguanylate cyclase activity
BP422_RS16980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BP422_RS16985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BP422_RS16990	COG0454	-acetyltransferase
BP422_RS16995	COG0517	IMP dehydrogenase activity
BP422_RS17000	COG0123	including yeast histone deacetylase and acetoin utilization protein
BP422_RS17005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BP422_RS17020	COG1605	Chorismate mutase
BP422_RS17020	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BP422_RS17030	COG3118	belongs to the thioredoxin family
BP422_RS17055	COG2309	aminopeptidase activity
BP422_RS17060	COG1695	Transcriptional regulator
BP422_RS17075	COG1733	regulation of RNA biosynthetic process
BP422_RS17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BP422_RS17105	COG2267	carboxylic ester hydrolase activity
BP422_RS17110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS17120	COG0436	Aminotransferase
BP422_RS17125	COG2814	Major facilitator Superfamily
BP422_RS17130	COG0315	cyclic pyranopterin monophosphate synthase activity
BP422_RS17135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BP422_RS17150	COG0314	molybdopterin synthase activity
BP422_RS17155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BP422_RS17160	COG5002	protein histidine kinase activity
BP422_RS17165	COG0745	RESPONSE REGULATOR receiver
BP422_RS17170	COG1132	(ABC) transporter
BP422_RS17180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BP422_RS17235	COG2271	Major facilitator Superfamily
BP422_RS17240	COG1414	Transcriptional regulator
BP422_RS17245	COG0656	L-ascorbic acid biosynthetic process
BP422_RS17265	COG3314	Sporulation integral membrane protein YlbJ
BP422_RS17270	COG1228	amidohydrolase
BP422_RS17275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BP422_RS17280	COG2207	Transcriptional regulator
BP422_RS17295	COG3829	transcription factor binding
BP422_RS17300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS17305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BP422_RS17330	COG1181	Belongs to the D-alanine--D-alanine ligase family
BP422_RS17340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BP422_RS17350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BP422_RS17370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BP422_RS17385	COG0489	protein tyrosine kinase activity
BP422_RS17395	COG1316	TRANSCRIPTIONal
BP422_RS17425	COG1674	ftsk spoiiie
BP422_RS17435	COG0529	Catalyzes the synthesis of activated sulfate
BP422_RS17440	COG2046	Belongs to the sulfate adenylyltransferase family
BP422_RS17445	COG0175	sulfate reduction
BP422_RS17450	COG1587	Uroporphyrinogen-III synthase
BP422_RS17450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BP422_RS17460	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BP422_RS17470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BP422_RS17495	COG0483	inositol monophosphate 1-phosphatase activity
BP422_RS17510	COG0129	dihydroxy-acid dehydratase activity
BP422_RS17515	COG0791	NLP P60 protein
BP422_RS17525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BP422_RS17535	COG4565	transcriptional regulatory protein
BP422_RS17540	COG3290	protein histidine kinase activity
BP422_RS17545	COG2851	Citrate transporter
BP422_RS17555	COG1131	(ABC) transporter
BP422_RS17590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BP422_RS17630	COG0488	(ABC) transporter
BP422_RS17655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS17660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS17665	COG0765	amino acid transport
BP422_RS17670	COG1126	abc transporter atp-binding protein
BP422_RS17695	COG0778	Nitroreductase
BP422_RS17700	COG2755	lipolytic protein G-D-S-L family
BP422_RS17710	COG0583	DNA-binding transcription factor activity
BP422_RS17715	COG0456	acetyltransferase
BP422_RS17720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS17725	COG0697	spore germination
BP422_RS17730	COG3387	PFAM Glycoside hydrolase 15-related
BP422_RS17735	COG0483	inositol monophosphate 1-phosphatase activity
BP422_RS17745	COG1966	Carbon starvation protein
BP422_RS17760	COG3275	phosphorelay sensor kinase activity
BP422_RS17765	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BP422_RS17770	COG3118	belongs to the thioredoxin family
BP422_RS17775	COG1959	2 iron, 2 sulfur cluster binding
BP422_RS17780	COG3118	belongs to the thioredoxin family
BP422_RS17785	COG1959	2 iron, 2 sulfur cluster binding
BP422_RS17790	COG2226	methyltransferase
BP422_RS17815	COG0745	RESPONSE REGULATOR receiver
BP422_RS17830	COG0840	transmembrane signaling receptor activity
BP422_RS17845	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BP422_RS17845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BP422_RS17855	COG1280	lysine exporter protein (LysE YggA)
BP422_RS17860	COG1522	sequence-specific DNA binding
BP422_RS17865	COG2814	Major facilitator Superfamily
BP422_RS17880	COG1595	DNA-templated transcription, initiation
BP422_RS17890	COG1363	Peptidase, m42
BP422_RS17905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP422_RS17910	COG2357	RelA SpoT domain protein
BP422_RS17915	COG0840	transmembrane signaling receptor activity
BP422_RS17930	COG4166	transmembrane transport
BP422_RS17935	COG2205	protein histidine kinase activity
BP422_RS17940	COG0826	peptidase U32
BP422_RS17955	COG1595	DNA-templated transcription, initiation
BP422_RS17960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BP422_RS17970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS17975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BP422_RS17985	COG0189	ligase activity
BP422_RS17990	COG1473	amidohydrolase
BP422_RS18005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BP422_RS18010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS18030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BP422_RS18040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS18060	COG5002	protein histidine kinase activity
BP422_RS18065	COG0745	RESPONSE REGULATOR receiver
BP422_RS18075	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BP422_RS18080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BP422_RS18085	COG0697	spore germination
BP422_RS18090	COG0531	amino acid
BP422_RS18115	COG0596	Alpha beta hydrolase
BP422_RS18140	COG0346	lactoylglutathione lyase activity
BP422_RS18175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BP422_RS18200	COG4549	nuclear export factor GLE1
BP422_RS18210	COG0596	Alpha beta hydrolase
BP422_RS18230	COG1177	transmembrane transport
BP422_RS18245	COG0697	spore germination
BP422_RS18250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS18260	COG0542	response to heat
BP422_RS18270	COG1309	transcriptional regulator
BP422_RS18280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BP422_RS18285	COG1515	deoxyribonuclease V activity
BP422_RS18295	COG2226	methyltransferase
BP422_RS18295	COG3433	isochorismatase activity
BP422_RS18295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS18300	COG3321	synthase
BP422_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS18300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS18300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS18300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BP422_RS18310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BP422_RS18310	COG2226	methyltransferase
BP422_RS18310	COG3433	isochorismatase activity
BP422_RS18315	COG1021	2,3-dihydroxybenzoate-AMP ligase
BP422_RS18500	COG0631	protein serine/threonine phosphatase activity
BP422_RS18565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BP422_RS18570	COG2070	2-Nitropropane dioxygenase
BP422_RS18580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS18585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS18600	COG1349	DNA-binding transcription factor activity
BP422_RS18610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BP422_RS18615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BP422_RS18615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BP422_RS18625	COG3842	ATPase activity
BP422_RS18630	COG1840	ABC-type Fe3 transport system, periplasmic component
BP422_RS18635	COG1794	racemase activity, acting on amino acids and derivatives
BP422_RS18710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BP422_RS18715	COG2971	BadF BadG BcrA BcrD
BP422_RS18720	COG0165	Argininosuccinate lyase
BP422_RS18740	COG3842	ATPase activity
BP422_RS18745	COG1840	ABC-type Fe3 transport system, periplasmic component
BP422_RS18765	COG0583	DNA-binding transcription factor activity
BP422_RS18775	COG1473	amidohydrolase
BP422_RS18780	COG1288	antiporter activity
BP422_RS18795	COG1414	Transcriptional regulator
BP422_RS18800	COG0765	amino acid transport
BP422_RS18805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS18845	COG0003	Pfam Anion-transporting ATPase
BP422_RS18865	COG1215	transferase activity, transferring glycosyl groups
BP422_RS18885	COG4129	membrane
BP422_RS18895	COG3253	May function as heme-dependent peroxidase
BP422_RS18900	COG0363	glucosamine-6-phosphate deaminase activity
BP422_RS18905	COG1737	Transcriptional regulator
BP422_RS18925	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS18930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BP422_RS18935	COG3938	Belongs to the proline racemase family
BP422_RS18940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BP422_RS18945	COG2204	response regulator
BP422_RS18965	COG0411	ABC transporter
BP422_RS18990	COG0006	proline dipeptidase activity
BP422_RS19040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BP422_RS19050	COG0656	L-ascorbic acid biosynthetic process
BP422_RS19055	COG1733	regulation of RNA biosynthetic process
BP422_RS19080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BP422_RS19085	COG0720	synthase
BP422_RS19095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BP422_RS19110	COG2346	COG2346, Truncated hemoglobins
BP422_RS19120	COG0456	acetyltransferase
BP422_RS19125	COG0681	Belongs to the peptidase S26 family
BP422_RS19140	COG1191	sigma factor activity
BP422_RS19145	COG1357	PFAM Pentapeptide repeats (8 copies)
BP422_RS19150	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS19155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS19165	COG1607	acyl-coa hydrolase
BP422_RS19185	COG0628	permease
BP422_RS19190	COG2084	Dehydrogenase
BP422_RS19200	COG1285	pathogenesis
BP422_RS19210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BP422_RS19215	COG0395	ABC-type sugar transport system, permease component
BP422_RS19235	COG2207	Transcriptional regulator
BP422_RS19235	COG4753	response regulator
BP422_RS19240	COG2972	Histidine kinase
BP422_RS19255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BP422_RS19270	COG4166	transmembrane transport
BP422_RS19280	COG5583	Uncharacterized small protein (DUF2292)
BP422_RS19285	COG4608	Belongs to the ABC transporter superfamily
BP422_RS19290	COG0444	Belongs to the ABC transporter superfamily
BP422_RS19300	COG0601	transmembrane transport
BP422_RS19305	COG0747	negative chemotaxis
BP422_RS19315	COG1309	transcriptional regulator
BP422_RS19335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BP422_RS19345	COG0789	Transcriptional regulator
BP422_RS19355	COG2909	trisaccharide binding
BP422_RS19370	COG1846	Transcriptional regulator
BP422_RS19380	COG2311	Membrane
BP422_RS19420	COG1309	transcriptional regulator
BP422_RS19460	COG2204	response regulator
BP422_RS19465	COG3135	benzoate transporter
BP422_RS19475	COG1924	4 iron, 4 sulfur cluster binding
BP422_RS19485	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS19495	COG0477	Major facilitator Superfamily
BP422_RS19500	COG2207	Transcriptional regulator
BP422_RS19510	COG0697	spore germination
BP422_RS19520	COG0095	Lipoate-protein ligase
BP422_RS19525	COG0840	transmembrane signaling receptor activity
BP422_RS19530	COG5002	protein histidine kinase activity
BP422_RS19540	COG0640	Transcriptional regulator
BP422_RS19545	COG0697	spore germination
BP422_RS19560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS19565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS19575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BP422_RS19580	COG0745	RESPONSE REGULATOR receiver
BP422_RS19585	COG5002	protein histidine kinase activity
BP422_RS19595	COG0596	Alpha beta hydrolase
BP422_RS19600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS19605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS19610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BP422_RS19615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS19615	COG2207	Transcriptional regulator
BP422_RS19620	COG0768	penicillin binding
BP422_RS19625	COG0768	penicillin binding
BP422_RS19635	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BP422_RS19690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BP422_RS19720	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BP422_RS19725	COG1472	Belongs to the glycosyl hydrolase 3 family
BP422_RS19735	COG0395	ABC-type sugar transport system, permease component
BP422_RS19740	COG1175	transmembrane transport
BP422_RS19750	COG1737	Transcriptional regulator
BP422_RS19810	COG0243	molybdopterin cofactor binding
BP422_RS19820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BP422_RS19825	COG2223	nitrite transmembrane transporter activity
BP422_RS19830	COG1151	hydroxylamine reductase activity
BP422_RS19850	COG1595	DNA-templated transcription, initiation
BP422_RS19855	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BP422_RS19860	COG0531	amino acid
BP422_RS19930	COG2135	peptidase activity
BP422_RS19970	COG2814	Major facilitator Superfamily
BP422_RS20035	COG0741	lytic transglycosylase activity
BP422_RS20035	COG1196	nuclear chromosome segregation
BP422_RS20035	COG0739	heme binding
BP422_RS20055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BP422_RS20060	COG1832	CoA-binding protein
BP422_RS20075	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BP422_RS20085	COG3584	3D domain protein
BP422_RS20105	COG1252	NADH dehydrogenase
BP422_RS20135	COG1408	metallophosphoesterase
BP422_RS20165	COG0316	Belongs to the HesB IscA family
BP422_RS20175	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BP422_RS20185	COG1252	NADH dehydrogenase
BP422_RS20190	COG0494	nUDIX hydrolase
BP422_RS20195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS20220	COG4837	Protein of unknown function (DUF1462)
BP422_RS20225	COG0626	cystathionine gamma-synthase activity
BP422_RS20230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BP422_RS20235	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BP422_RS20245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BP422_RS20255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BP422_RS20260	COG0647	UMP catabolic process
BP422_RS20290	COG2801	Transposase and inactivated derivatives
BP422_RS20295	COG1705	Flagellar rod assembly protein muramidase FlgJ
BP422_RS20320	COG3299	homolog of phage Mu protein gp47
BP422_RS20355	COG2801	Transposase and inactivated derivatives
BP422_RS20365	COG2445	Protein of unknown function DUF86
BP422_RS20375	COG1494	fructose-1,6-bisphosphatase
BP422_RS20390	COG4470	Protein conserved in bacteria
BP422_RS20400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BP422_RS20410	COG0420	3'-5' exonuclease activity
BP422_RS20415	COG0693	protein deglycase activity
BP422_RS20420	COG0739	heme binding
BP422_RS20450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BP422_RS20455	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BP422_RS20455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BP422_RS20465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BP422_RS20465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BP422_RS20500	COG0840	transmembrane signaling receptor activity
BP422_RS20510	COG0598	Magnesium transport protein CorA
BP422_RS20525	COG3377	Domain of unknown function (DUF1805)
BP422_RS20535	COG0737	Belongs to the 5'-nucleotidase family
BP422_RS20540	COG0730	response to heat
BP422_RS20545	COG1801	Protein of unknown function DUF72
BP422_RS20555	COG0527	aspartate kinase activity
BP422_RS20565	COG2268	Band 7 protein
BP422_RS20575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS20580	COG0697	spore germination
BP422_RS20620	COG2801	Transposase and inactivated derivatives
BP422_RS20630	COG0719	Fe-S assembly protein
BP422_RS20635	COG0822	iron-sulfur transferase activity
BP422_RS20640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BP422_RS20645	COG0719	Fe-S assembly protein
BP422_RS20650	COG0396	ATPase activity
BP422_RS20660	COG1115	amino acid carrier protein
BP422_RS20665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BP422_RS20670	COG1473	amidohydrolase
BP422_RS20690	COG0840	transmembrane signaling receptor activity
BP422_RS20695	COG0509	glycine decarboxylation via glycine cleavage system
BP422_RS20700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP422_RS20705	COG0436	Aminotransferase
BP422_RS20710	COG1393	Belongs to the ArsC family
BP422_RS20735	COG1126	abc transporter atp-binding protein
BP422_RS20740	COG0616	signal peptide processing
BP422_RS20750	COG2340	Cysteine-rich secretory protein family
BP422_RS20765	COG0477	Major facilitator Superfamily
BP422_RS20775	COG1132	(ABC) transporter
BP422_RS20785	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BP422_RS20790	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BP422_RS20800	COG1595	DNA-templated transcription, initiation
BP422_RS20805	COG1850	ribulose-bisphosphate carboxylase activity
BP422_RS20810	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BP422_RS20815	COG0235	Class ii aldolase
BP422_RS20820	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BP422_RS20830	COG0531	amino acid
BP422_RS20835	COG0697	spore germination
BP422_RS20840	COG1960	acyl-CoA dehydrogenase activity
BP422_RS20845	COG0183	Belongs to the thiolase family
BP422_RS20850	COG1024	Enoyl-CoA hydratase
BP422_RS20850	COG1250	3-hydroxyacyl-CoA dehydrogenase
BP422_RS20885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BP422_RS20900	COG5577	PFAM Coat F domain
BP422_RS20905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS20910	COG1279	arginine transmembrane transporter activity
BP422_RS20915	COG1392	Phosphate transport regulator
BP422_RS20920	COG0306	phosphate transporter
BP422_RS20950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BP422_RS20955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BP422_RS20965	COG1376	ErfK ybiS ycfS ynhG family protein
BP422_RS20990	COG1122	ATPase activity
BP422_RS21000	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
BP422_RS21005	COG0310	cobalt ion transport
BP422_RS21010	COG0167	dihydroorotate dehydrogenase activity
BP422_RS21015	COG0686	Belongs to the AlaDH PNT family
BP422_RS21020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BP422_RS21020	COG2508	Transcriptional regulator
BP422_RS21030	COG0477	Major facilitator Superfamily
BP422_RS21040	COG2201	protein-glutamate methylesterase activity
BP422_RS21050	COG1744	ABC transporter substrate-binding protein PnrA-like
BP422_RS21055	COG4191	Histidine kinase
BP422_RS21060	COG1506	peptidase
BP422_RS21065	COG0583	DNA-binding transcription factor activity
BP422_RS21075	COG1098	S1 RNA binding domain
BP422_RS21080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BP422_RS21100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BP422_RS21125	COG0788	formyltetrahydrofolate deformylase activity
BP422_RS21130	COG1309	transcriptional regulator
BP422_RS21135	COG0842	Transport permease protein
BP422_RS21140	COG1131	(ABC) transporter
BP422_RS21145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BP422_RS21150	COG0346	lactoylglutathione lyase activity
BP422_RS21155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BP422_RS21155	COG0551	DNA topoisomerase type I activity
BP422_RS21160	COG0789	Transcriptional regulator
BP422_RS21170	COG0477	Major facilitator Superfamily
BP422_RS21175	COG0528	UMP kinase activity
BP422_RS21185	COG0531	amino acid
BP422_RS21190	COG2318	DinB family
BP422_RS21200	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BP422_RS21205	COG0419	ATPase involved in DNA repair
BP422_RS21210	COG0420	3'-5' exonuclease activity
BP422_RS21220	COG1612	heme a metabolic process
BP422_RS21225	COG0109	protoheme IX farnesyltransferase activity
BP422_RS21235	COG3336	cytochrome c oxidase
BP422_RS21245	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS21250	COG2151	metal-sulfur cluster biosynthetic enzyme
BP422_RS21265	COG3396	Phenylacetate-CoA oxygenase
BP422_RS21270	COG0840	transmembrane signaling receptor activity
BP422_RS21280	COG0410	ABC transporter
BP422_RS21310	COG0183	Belongs to the thiolase family
BP422_RS21315	COG0183	Belongs to the thiolase family
BP422_RS21320	COG1250	3-hydroxyacyl-CoA dehydrogenase
BP422_RS21325	COG1250	3-hydroxyacyl-CoA dehydrogenase
BP422_RS21330	COG1024	Enoyl-CoA hydratase
BP422_RS21340	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BP422_RS21345	COG1024	Enoyl-CoA hydratase
BP422_RS21350	COG2050	protein possibly involved in aromatic compounds catabolism
BP422_RS21355	COG2050	protein possibly involved in aromatic compounds catabolism
BP422_RS21365	COG0702	epimerase
BP422_RS21370	COG3631	Ketosteroid isomerase-related protein
BP422_RS21375	COG1309	transcriptional regulator
BP422_RS21380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BP422_RS21395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BP422_RS21395	COG2010	Cytochrome c
BP422_RS21400	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS21420	COG0697	spore germination
BP422_RS21425	COG0544	peptidyl-prolyl cis-trans isomerase activity
BP422_RS21435	COG1131	(ABC) transporter
BP422_RS21475	COG0714	Associated with various cellular activities
BP422_RS21490	COG1131	(ABC) transporter
BP422_RS21500	COG0506	proline dehydrogenase activity
BP422_RS21505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS21510	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BP422_RS21515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BP422_RS21520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BP422_RS21525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BP422_RS21535	COG2076	Multidrug Resistance protein
BP422_RS21545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS21565	COG0640	Transcriptional regulator
BP422_RS21595	COG3359	exonuclease
BP422_RS21600	COG1205	dead DEAH box helicase
BP422_RS21600	COG1111	helicase
BP422_RS21605	COG3226	Transcriptional regulator
BP422_RS21620	COG2140	Oxalate decarboxylase
BP422_RS21625	COG2814	Major facilitator Superfamily
BP422_RS21650	COG2255	four-way junction helicase activity
BP422_RS21660	COG2304	oxidoreductase activity
BP422_RS21665	COG0586	Pfam SNARE associated Golgi protein
BP422_RS21670	COG2207	Transcriptional regulator
BP422_RS21675	COG0154	amidase activity
BP422_RS21685	COG2113	Glycine betaine
BP422_RS21695	COG0517	IMP dehydrogenase activity
BP422_RS21695	COG4175	Glycine betaine
BP422_RS21700	COG1510	regulation of RNA biosynthetic process
BP422_RS21715	COG4895	conserved protein (DUF2196)
BP422_RS21730	COG0745	RESPONSE REGULATOR receiver
BP422_RS21735	COG5002	protein histidine kinase activity
BP422_RS21755	COG4191	Histidine kinase
BP422_RS21765	COG0463	Glycosyl transferase, family 2
BP422_RS21785	COG5632	N-Acetylmuramoyl-L-alanine amidase
BP422_RS21785	COG3409	Peptidoglycan-binding domain 1 protein
BP422_RS21880	COG3677	Transposase
BP422_RS21910	COG0519	Catalyzes the synthesis of GMP from XMP
BP422_RS21915	COG0024	Methionine aminopeptidase
BP422_RS21945	COG3850	Histidine kinase
BP422_RS21945	COG5002	protein histidine kinase activity
BP422_RS21950	COG0745	RESPONSE REGULATOR receiver
BP422_RS21960	COG1929	Belongs to the glycerate kinase type-1 family
BP422_RS21965	COG4214	carbohydrate transport
BP422_RS21970	COG1129	ABC transporter
BP422_RS21980	COG4191	Histidine kinase
BP422_RS21985	COG2323	membrane
BP422_RS21990	COG1414	Transcriptional regulator
BP422_RS22000	COG1918	ferrous iron import across plasma membrane
BP422_RS22000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BP422_RS22005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BP422_RS22010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BP422_RS22025	COG1252	NADH dehydrogenase
BP422_RS22075	COG3711	transcriptional antiterminator
BP422_RS22080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BP422_RS22080	COG1263	PTS System
BP422_RS22100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BP422_RS22110	COG0697	spore germination
BP422_RS22185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BP422_RS22190	COG0747	negative chemotaxis
BP422_RS22210	COG4608	Belongs to the ABC transporter superfamily
BP422_RS22215	COG0444	Belongs to the ABC transporter superfamily
BP422_RS22220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS22225	COG0601	transmembrane transport
BP422_RS22275	COG3284	Transcriptional regulator
BP422_RS22280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BP422_RS22285	COG0508	dehydrogenase complex catalyzes the overall conversion of
BP422_RS22290	COG0022	dehydrogenase e1 component
BP422_RS22295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BP422_RS22330	COG0657	acetylesterase activity
BP422_RS22340	COG2814	Major facilitator Superfamily
BP422_RS22355	COG1309	transcriptional regulator
BP422_RS22360	COG0697	spore germination
BP422_RS22370	COG2801	Transposase and inactivated derivatives
BP422_RS22385	COG2801	Transposase and inactivated derivatives
BP422_RS22405	COG1595	DNA-templated transcription, initiation
BP422_RS22415	COG1733	regulation of RNA biosynthetic process
BP422_RS22420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BP422_RS22425	COG0778	Nitroreductase
BP422_RS22465	COG0477	Major facilitator Superfamily
BP422_RS22495	COG4608	Belongs to the ABC transporter superfamily
BP422_RS22500	COG0444	Belongs to the ABC transporter superfamily
BP422_RS22505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS22510	COG0601	transmembrane transport
BP422_RS22530	COG0544	peptidyl-prolyl cis-trans isomerase activity
BP422_RS22540	COG5002	protein histidine kinase activity
BP422_RS22545	COG0745	RESPONSE REGULATOR receiver
BP422_RS22580	COG3706	GGDEF domain
BP422_RS22590	COG1114	Component of the transport system for branched-chain amino acids
BP422_RS22610	COG0515	serine threonine protein kinase
BP422_RS22610	COG2815	serine threonine protein kinase
BP422_RS22680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BP422_RS22685	COG0557	exoribonuclease II activity
BP422_RS22690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BP422_RS22700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BP422_RS22705	COG0390	transport system, permease component
BP422_RS22720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS22725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS22730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS22740	COG1120	ATPase activity
BP422_RS22745	COG0789	Transcriptional regulator
BP422_RS22750	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS22755	COG0148	phosphopyruvate hydratase activity
BP422_RS22765	COG0149	triose-phosphate isomerase activity
BP422_RS22770	COG0126	phosphoglycerate kinase activity
BP422_RS22780	COG1757	Na H antiporter
BP422_RS22795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BP422_RS22800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS22825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS22830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS22835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS22840	COG4191	Histidine kinase
BP422_RS22885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BP422_RS22890	COG1481	regulation of sporulation
BP422_RS22895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BP422_RS22905	COG0492	ferredoxin-NADP+ reductase activity
BP422_RS22950	COG0140	phosphoribosyl-ATP diphosphatase activity
BP422_RS22950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BP422_RS22955	COG0107	imidazoleglycerol-phosphate synthase activity
BP422_RS22960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BP422_RS22965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BP422_RS22970	COG0131	Imidazoleglycerol-phosphate dehydratase
BP422_RS22975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BP422_RS22980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BP422_RS22985	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BP422_RS22990	COG0110	maltose O-acetyltransferase activity
BP422_RS22995	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BP422_RS23000	COG1950	PFAM Membrane protein of
BP422_RS23005	COG1418	mRNA catabolic process
BP422_RS23010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BP422_RS23015	COG0556	nucleotide-excision repair
BP422_RS23035	COG0793	Belongs to the peptidase S41A family
BP422_RS23035	COG3409	Peptidoglycan-binding domain 1 protein
BP422_RS23040	COG0739	heme binding
BP422_RS23045	COG2177	Part of the ABC transporter FtsEX involved in
BP422_RS23050	COG2884	Cell division ATP-binding protein ftsE
BP422_RS23055	COG1979	alcohol dehydrogenase
BP422_RS23065	COG0531	amino acid
BP422_RS23075	COG0165	Argininosuccinate lyase
BP422_RS23080	COG0137	argininosuccinate synthase activity
BP422_RS23090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BP422_RS23090	COG2199	diguanylate cyclase activity
BP422_RS23100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BP422_RS23105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BP422_RS23110	COG0505	Belongs to the CarA family
BP422_RS23115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BP422_RS23120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BP422_RS23125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BP422_RS23140	COG5002	protein histidine kinase activity
BP422_RS23145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BP422_RS23160	COG0653	protein targeting
BP422_RS23165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BP422_RS23175	COG1278	Cold shock
BP422_RS23180	COG0765	amino acid transport
BP422_RS23215	COG1516	flagellar protein fliS
BP422_RS23220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BP422_RS23225	COG1334	flagellar protein FlaG
BP422_RS23230	COG0457	Tetratricopeptide repeat
BP422_RS23230	COG0463	Glycosyl transferase, family 2
BP422_RS23235	COG0463	Glycosyl transferase, family 2
BP422_RS23240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BP422_RS23245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BP422_RS23250	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BP422_RS23260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BP422_RS23265	COG1256	bacterial-type flagellum assembly
BP422_RS23265	COG4786	Flagellar basal body rod
BP422_RS23290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BP422_RS23310	COG1649	PFAM Uncharacterised BCR, COG1649
BP422_RS23310	COG0726	polysaccharide deacetylase
BP422_RS23315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BP422_RS23320	COG1404	Belongs to the peptidase S8 family
BP422_RS23345	COG4974	Belongs to the 'phage' integrase family
BP422_RS23355	COG0544	peptidyl-prolyl cis-trans isomerase activity
BP422_RS23360	COG2373	Large extracellular alpha-helical protein
BP422_RS23370	COG1739	Uncharacterized protein family UPF0029
BP422_RS23380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BP422_RS23385	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BP422_RS23410	COG4786	Flagellar basal body rod
BP422_RS23420	COG1609	Transcriptional regulator
BP422_RS23425	COG0739	heme binding
BP422_RS23435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BP422_RS23450	COG1007	ATP synthesis coupled electron transport
BP422_RS23455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BP422_RS23460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BP422_RS23465	COG0713	ATP synthesis coupled electron transport
BP422_RS23475	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BP422_RS23480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BP422_RS23485	COG0649	NAD binding
BP422_RS23490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BP422_RS23495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BP422_RS23500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BP422_RS23510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BP422_RS23515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BP422_RS23520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BP422_RS23525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BP422_RS23530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BP422_RS23535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BP422_RS23545	COG0356	it plays a direct role in the translocation of protons across the membrane
BP422_RS23565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS23565	COG2207	Transcriptional regulator
BP422_RS23570	COG4106	trans-aconitate 2-methyltransferase activity
BP422_RS23575	COG0596	Alpha beta hydrolase
BP422_RS23580	COG0156	8-amino-7-oxononanoate synthase activity
BP422_RS23585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BP422_RS23590	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BP422_RS23595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BP422_RS23605	COG3206	protein involved in exopolysaccharide biosynthesis
BP422_RS23610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BP422_RS23615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BP422_RS23625	COG4475	Protein of unknown function (DUF436)
BP422_RS23630	COG0698	ribose 5-phosphate isomerase
BP422_RS23640	COG1971	Probably functions as a manganese efflux pump
BP422_RS23645	COG0009	L-threonylcarbamoyladenylate synthase
BP422_RS23660	COG2890	protein-(glutamine-N5) methyltransferase activity
BP422_RS23665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BP422_RS23675	COG1435	thymidine kinase activity
BP422_RS23680	COG0415	Belongs to the DNA photolyase family
BP422_RS23685	COG0254	rRNA binding
BP422_RS23695	COG0739	heme binding
BP422_RS23700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BP422_RS23705	COG1494	fructose-1,6-bisphosphatase
BP422_RS23710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BP422_RS23715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BP422_RS23720	COG0191	fructose-bisphosphate aldolase activity
BP422_RS23725	COG2204	response regulator
BP422_RS23735	COG0504	CTP synthase activity
BP422_RS23740	COG3343	RNA polymerase activity
BP422_RS23745	COG1703	isobutyryl-CoA mutase activity
BP422_RS23745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BP422_RS23745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BP422_RS23750	COG1309	transcriptional regulator
BP422_RS23755	COG1960	acyl-CoA dehydrogenase activity
BP422_RS23760	COG1960	acyl-CoA dehydrogenase activity
BP422_RS23765	COG1250	3-hydroxyacyl-CoA dehydrogenase
BP422_RS23770	COG0183	Belongs to the thiolase family
BP422_RS23780	COG1595	DNA-templated transcription, initiation
BP422_RS23785	COG2181	nitrate reductase activity
BP422_RS23785	COG0247	lactate metabolic process
BP422_RS23790	COG1509	lysine 2,3-aminomutase activity
BP422_RS23795	COG3829	transcription factor binding
BP422_RS23815	COG0010	Belongs to the arginase family
BP422_RS23820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BP422_RS23825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BP422_RS23865	COG3465	dGTPase activity
BP422_RS23870	COG1078	dGTPase activity
BP422_RS23885	COG1309	transcriptional regulator
BP422_RS23890	COG1664	Polymer-forming cytoskeletal
BP422_RS23895	COG0789	Transcriptional regulator
BP422_RS23905	COG0564	pseudouridine synthase activity
BP422_RS23935	COG0116	Belongs to the methyltransferase superfamily
BP422_RS23940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BP422_RS23960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BP422_RS23975	COG2329	Antibiotic biosynthesis monooxygenase
BP422_RS23980	COG2204	response regulator
BP422_RS23985	COG0626	cystathionine gamma-synthase activity
BP422_RS24005	COG2267	carboxylic ester hydrolase activity
BP422_RS24015	COG1122	ATPase activity
BP422_RS24020	COG1122	ATPase activity
BP422_RS24035	COG0531	amino acid
BP422_RS24050	COG0405	Gamma-glutamyltransferase
BP422_RS24060	COG0584	glycerophosphoryl diester phosphodiesterase
BP422_RS24065	COG1653	transport
BP422_RS24070	COG0395	ABC-type sugar transport system, permease component
BP422_RS24075	COG1175	transmembrane transport
BP422_RS24080	COG3842	ATPase activity
BP422_RS24085	COG0546	phosphoglycolate phosphatase activity
BP422_RS24100	COG0813	purine-nucleoside phosphorylase activity
BP422_RS24105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BP422_RS24110	COG1079	Belongs to the binding-protein-dependent transport system permease family
BP422_RS24115	COG4603	Belongs to the binding-protein-dependent transport system permease family
BP422_RS24120	COG3845	ABC transporter
BP422_RS24140	COG1846	Transcriptional regulator
BP422_RS24170	COG0833	amino acid
BP422_RS24180	COG1414	Transcriptional regulator
BP422_RS24185	COG4187	Peptidase family M20/M25/M40
BP422_RS24190	COG1765	OsmC-like protein
BP422_RS24200	COG2309	aminopeptidase activity
BP422_RS24280	COG0039	L-malate dehydrogenase activity
BP422_RS24285	COG4302	ethanolamine ammonia-lyase activity
BP422_RS24290	COG4303	Ethanolamine ammonia lyase large subunit
BP422_RS24310	COG1160	GTP binding
BP422_RS24320	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BP422_RS24330	COG4869	propanediol catabolic process
BP422_RS24340	COG1454	alcohol dehydrogenase
BP422_RS24340	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS24345	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BP422_RS24370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BP422_RS24385	COG0513	Belongs to the DEAD box helicase family
BP422_RS24395	COG0840	transmembrane signaling receptor activity
BP422_RS24400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BP422_RS24405	COG0277	FAD linked oxidase domain protein
BP422_RS24410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BP422_RS24410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BP422_RS24415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BP422_RS24420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BP422_RS24425	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS24430	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS24435	COG0473	3-isopropylmalate dehydrogenase activity
BP422_RS24440	COG3284	Transcriptional regulator
BP422_RS24445	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS24460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BP422_RS24470	COG2205	protein histidine kinase activity
BP422_RS24475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BP422_RS24480	COG0561	phosphatase activity
BP422_RS24485	COG1486	melibiose metabolic process
BP422_RS24490	COG1447	Phosphotransferase system cellobiose-specific component IIA
BP422_RS24495	COG3394	polysaccharide catabolic process
BP422_RS24515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BP422_RS24515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BP422_RS24520	COG0745	RESPONSE REGULATOR receiver
BP422_RS24520	COG4191	Histidine kinase
BP422_RS24520	COG2205	protein histidine kinase activity
BP422_RS24545	COG0514	ATP-dependent DNA helicase (RecQ)
BP422_RS24570	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS24580	COG1285	pathogenesis
BP422_RS24585	COG0534	Mate efflux family protein
BP422_RS24590	COG3397	chitin binding
BP422_RS24595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BP422_RS24600	COG3842	ATPase activity
BP422_RS24610	COG1176	ABC-type spermidine putrescine transport system, permease component I
BP422_RS24640	COG2011	ABC-type metal ion transport system permease component
BP422_RS24655	COG1120	ATPase activity
BP422_RS24665	COG4607	ABC-type enterochelin transport system periplasmic component
BP422_RS24670	COG4604	ABC transporter, ATP-binding protein
BP422_RS24675	COG4605	iron ion homeostasis
BP422_RS24680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS24700	COG2201	protein-glutamate methylesterase activity
BP422_RS24715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS24765	COG1280	lysine exporter protein (LysE YggA)
BP422_RS24790	COG1649	PFAM Uncharacterised BCR, COG1649
BP422_RS24800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BP422_RS24825	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BP422_RS24835	COG0395	ABC-type sugar transport system, permease component
BP422_RS24850	COG3842	ATPase activity
BP422_RS24855	COG0584	glycerophosphoryl diester phosphodiesterase
BP422_RS24910	COG0672	)-iron permease
BP422_RS24915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BP422_RS24920	COG2076	Multidrug Resistance protein
BP422_RS24950	COG1968	undecaprenyl-diphosphatase activity
BP422_RS24960	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS24965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BP422_RS24970	COG2204	response regulator
BP422_RS24980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BP422_RS24990	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BP422_RS24995	COG3829	transcription factor binding
BP422_RS25000	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS25005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BP422_RS25010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BP422_RS25020	COG1846	Transcriptional regulator
BP422_RS25035	COG0477	Major facilitator Superfamily
BP422_RS25055	COG1846	Transcriptional regulator
BP422_RS25060	COG1764	response to oxidative stress
BP422_RS25070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS25075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS25080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BP422_RS25085	COG0457	Tetratricopeptide repeat
BP422_RS25085	COG0463	Glycosyl transferase, family 2
BP422_RS25135	COG0463	Glycosyl transferase, family 2
BP422_RS25135	COG0457	Tetratricopeptide repeat
BP422_RS25145	COG2824	Alkylphosphonate utilization operon protein PhnA
BP422_RS25150	COG2197	response regulator
BP422_RS25175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP422_RS25180	COG0765	amino acid transport
BP422_RS25185	COG1126	abc transporter atp-binding protein
BP422_RS25195	COG5578	integral membrane protein
BP422_RS25200	COG0395	ABC-type sugar transport system, permease component
BP422_RS25205	COG1175	transmembrane transport
BP422_RS25210	COG2182	Extracellular solute-binding protein
BP422_RS25215	COG4753	response regulator
BP422_RS25215	COG2207	Transcriptional regulator
BP422_RS25220	COG2972	Histidine kinase
BP422_RS25225	COG3250	beta-galactosidase activity
BP422_RS25230	COG1940	carbohydrate kinase activity
BP422_RS25240	COG2222	sugar isomerase
BP422_RS25255	COG0583	DNA-binding transcription factor activity
BP422_RS25260	COG0693	protein deglycase activity
BP422_RS25285	COG2814	Major facilitator Superfamily
BP422_RS25305	COG0346	lactoylglutathione lyase activity
BP422_RS25315	COG2214	Heat shock protein DnaJ domain protein
BP422_RS25325	COG1309	transcriptional regulator
BP422_RS25335	COG0456	acetyltransferase
BP422_RS25360	COG1404	Belongs to the peptidase S8 family
BP422_RS25375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BP422_RS25375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BP422_RS25375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BP422_RS25380	COG1105	Belongs to the carbohydrate kinase PfkB family
BP422_RS25385	COG1349	DNA-binding transcription factor activity
BP422_RS25390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS25395	COG0579	oxidoreductase
BP422_RS25415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BP422_RS25420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BP422_RS25425	COG2801	Transposase and inactivated derivatives
BP422_RS25450	COG1361	Conserved repeat domain
BP422_RS25455	COG2972	Histidine kinase
BP422_RS25455	COG0745	RESPONSE REGULATOR receiver
BP422_RS25460	COG3279	Response regulator of the LytR AlgR family
BP422_RS25465	COG1733	regulation of RNA biosynthetic process
BP422_RS25475	COG1573	uracil-dna glycosylase
BP422_RS25495	COG2814	Major facilitator Superfamily
BP422_RS25520	COG0840	transmembrane signaling receptor activity
BP422_RS25565	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BP422_RS25585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BP422_RS25590	COG4853	Protein conserved in bacteria
BP422_RS25600	COG5002	protein histidine kinase activity
BP422_RS25605	COG0745	RESPONSE REGULATOR receiver
BP422_RS25610	COG0739	heme binding
BP422_RS25610	COG1196	nuclear chromosome segregation
BP422_RS25610	COG0741	lytic transglycosylase activity
BP422_RS25625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BP422_RS25630	COG0305	Participates in initiation and elongation during chromosome replication
BP422_RS25635	COG0359	binds to the 23S rRNA
BP422_RS25640	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BP422_RS25650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BP422_RS25655	COG0629	single-stranded DNA binding
BP422_RS25660	COG0360	Binds together with S18 to 16S ribosomal RNA
BP422_RS25665	COG0012	GTP binding
BP422_RS25670	COG0702	epimerase
BP422_RS25675	COG1164	Oligoendopeptidase f
BP422_RS25690	COG4481	Protein conserved in bacteria
BP422_RS25695	COG0668	transmembrane transport
BP422_RS25710	COG1597	lipid kinase activity
BP422_RS25725	COG1475	DNA binding
BP422_RS25730	COG1192	Involved in chromosome partitioning
BP422_RS25740	COG1475	DNA binding
BP422_RS25760	COG0357	Ribosomal RNA small subunit methyltransferase G
BP422_RS25770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BP422_RS25775	COG1847	R3H domain protein
BP422_RS25780	COG0706	membrane insertase activity
BP422_RS25785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BP422_RS25790	COG0594	ribonuclease P activity
BP422_RS25800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BP422_RS25805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BP422_RS25810	COG0592	DNA-directed DNA polymerase activity
BP422_RS25815	COG2501	S4 domain
BP422_RS25820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BP422_RS25830	COG0187	DNA topoisomerase II activity
BP422_RS25970	COG3850	Histidine kinase
BP422_RS25970	COG5002	protein histidine kinase activity
BP422_RS25975	COG0745	RESPONSE REGULATOR receiver
BP422_RS26010	COG0516	GMP reductase activity
BP422_RS26010	COG0517	IMP dehydrogenase activity
BP422_RS26020	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BP422_RS26025	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BP422_RS26030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BP422_RS26040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BP422_RS26045	COG2224	Isocitrate lyase
BP422_RS26065	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BP422_RS26070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BP422_RS26075	COG1349	DNA-binding transcription factor activity
BP422_RS26080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BP422_RS26110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BP422_RS26125	COG2259	Doxx family
BP422_RS26130	COG1733	regulation of RNA biosynthetic process
BP422_RS26155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BP422_RS26165	COG2190	(PTS) system
BP422_RS26170	COG3711	transcriptional antiterminator
BP422_RS26180	COG0590	tRNA wobble adenosine to inosine editing
BP422_RS26185	COG1187	pseudouridine synthase activity
BP422_RS26195	COG1595	DNA-templated transcription, initiation
BP422_RS26200	COG0768	penicillin binding
BP422_RS26210	COG0425	Belongs to the sulfur carrier protein TusA family
BP422_RS26215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BP422_RS26215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BP422_RS26220	COG0425	Belongs to the sulfur carrier protein TusA family
BP422_RS26225	COG0730	response to heat
BP422_RS26230	COG2210	Belongs to the sulfur carrier protein TusA family
BP422_RS26235	COG1937	Protein conserved in bacteria
BP422_RS26245	COG2910	NAD(P)H-binding
BP422_RS26260	COG0586	Pfam SNARE associated Golgi protein
BP422_RS26270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BP422_RS26270	COG2199	diguanylate cyclase activity
BP422_RS26280	COG3852	Histidine kinase
BP422_RS26285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BP422_RS26290	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BP422_RS26295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BP422_RS26335	COG1982	Orn Lys Arg decarboxylase major
BP422_RS26340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BP422_RS26345	COG3870	Protein conserved in bacteria
BP422_RS26350	COG1728	Protein conserved in bacteria
BP422_RS26355	COG0470	DNA polymerase III
BP422_RS26360	COG1774	PSP1 C-terminal conserved region
BP422_RS26365	COG4467	Involved in initiation control of chromosome replication
BP422_RS26370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BP422_RS26380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BP422_RS26390	COG2002	toxin-antitoxin pair type II binding
BP422_RS26395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BP422_RS26395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BP422_RS26400	COG0084	hydrolase, TatD family'
BP422_RS26405	COG1388	LysM domain
BP422_RS26405	COG3584	3D domain protein
BP422_RS26415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BP422_RS26420	COG4466	Protein conserved in bacteria
BP422_RS26430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BP422_RS26435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BP422_RS26440	COG0251	oxidation-reduction process
BP422_RS26445	COG2088	sporulation resulting in formation of a cellular spore
BP422_RS26450	COG0523	cobalamin synthesis protein
BP422_RS26455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BP422_RS26460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BP422_RS26465	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BP422_RS26470	COG0193	aminoacyl-tRNA hydrolase activity
BP422_RS26480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BP422_RS26485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BP422_RS26490	COG2002	toxin-antitoxin pair type II binding
BP422_RS26495	COG2244	polysaccharide biosynthetic process
BP422_RS26500	COG3956	TIGRFAM MazG family protein
BP422_RS26505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BP422_RS26520	COG4533	DNA binding
BP422_RS26545	COG1098	S1 RNA binding domain
BP422_RS26550	COG2208	phosphoserine phosphatase activity
BP422_RS26555	COG2304	oxidoreductase activity
BP422_RS26560	COG0515	serine threonine protein kinase
BP422_RS26570	COG3610	response to peptide
BP422_RS26580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BP422_RS26585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BP422_RS26595	COG0561	phosphatase activity
BP422_RS26600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BP422_RS26610	COG1695	Transcriptional regulator
BP422_RS26620	COG0803	Belongs to the bacterial solute-binding protein 9 family
BP422_RS26620	COG3443	Belongs to the bacterial solute-binding protein 9 family
BP422_RS26625	COG1121	(ABC) transporter
BP422_RS26630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BP422_RS26635	COG0735	belongs to the Fur family
BP422_RS26640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BP422_RS26650	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BP422_RS26730	COG2894	cell division
BP422_RS26840	COG0601	transmembrane transport
BP422_RS26845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP422_RS26850	COG0444	Belongs to the ABC transporter superfamily
BP422_RS26855	COG4166	transmembrane transport
BP422_RS26860	COG4948	Mandelate Racemase Muconate Lactonizing
BP422_RS26865	COG0791	NLP P60 protein
BP422_RS26870	COG4608	Belongs to the ABC transporter superfamily
BP422_RS26875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BP422_RS26880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BP422_RS26885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BP422_RS26890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BP422_RS26895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BP422_RS26900	COG0512	Glutamine amidotransferase of anthranilate synthase
BP422_RS26910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BP422_RS26915	COG0805	protein transport
BP422_RS26920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BP422_RS26925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BP422_RS26930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BP422_RS26935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BP422_RS26940	COG1396	sequence-specific DNA binding
BP422_RS26945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BP422_RS26950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BP422_RS26985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BP422_RS26990	COG0546	phosphoglycolate phosphatase activity
BP422_RS27000	COG3880	PFAM UvrB UvrC protein
BP422_RS27005	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BP422_RS27010	COG0542	response to heat
BP422_RS27015	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BP422_RS27020	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BP422_RS27025	COG1183	phosphatidylcholine synthase activity
BP422_RS27035	COG4956	integral membrane protein (PIN domain superfamily)
BP422_RS27040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BP422_RS27045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BP422_RS27050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BP422_RS27055	COG1045	serine acetyltransferase
BP422_RS27060	COG0215	cysteine-tRNA ligase activity
BP422_RS27065	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BP422_RS27070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BP422_RS27075	COG3688	RNA-binding protein containing a PIN domain
BP422_RS27085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BP422_RS27095	COG0250	Participates in transcription elongation, termination and antitermination
BP422_RS27100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BP422_RS27105	COG0081	regulation of translation
BP422_RS27115	COG0222	ribosome binding
BP422_RS27120	COG2813	Specifically methylates the guanine in position
BP422_RS27125	COG0085	RNA polymerase activity
BP422_RS27130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BP422_RS27135	COG1358	cellular component organization or biogenesis
BP422_RS27140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BP422_RS27145	COG0049	tRNA binding
BP422_RS27150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BP422_RS27155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BP422_RS27160	COG0697	spore germination
BP422_RS27165	COG2346	COG2346, Truncated hemoglobins
BP422_RS27175	COG0051	transcription antitermination factor activity, RNA binding
BP422_RS27180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BP422_RS27185	COG0088	Forms part of the polypeptide exit tunnel
BP422_RS27190	COG0089	rRNA binding
BP422_RS27195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BP422_RS27200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BP422_RS27205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BP422_RS27210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BP422_RS27215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BP422_RS27220	COG0255	Belongs to the universal ribosomal protein uL29 family
BP422_RS27225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BP422_RS27230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BP422_RS27235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BP422_RS27240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BP422_RS27245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BP422_RS27250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BP422_RS27255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BP422_RS27260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BP422_RS27265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BP422_RS27270	COG1841	ribosomal large subunit assembly
BP422_RS27275	COG0200	Binds to the 23S rRNA
BP422_RS27280	COG0201	protein transport
BP422_RS27285	COG0563	adenylate kinase activity
BP422_RS27290	COG0024	Methionine aminopeptidase
BP422_RS27295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BP422_RS27300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BP422_RS27305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BP422_RS27310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BP422_RS27315	COG0202	RNA polymerase activity
BP422_RS27320	COG0203	ribosomal protein L17
BP422_RS27325	COG1122	ATPase activity
BP422_RS27330	COG1122	ATPase activity
BP422_RS27335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BP422_RS27340	COG0101	tRNA pseudouridine synthase activity
BP422_RS27345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BP422_RS27350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BP422_RS27355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS27360	COG0489	protein tyrosine kinase activity
BP422_RS27370	COG2194	sulfuric ester hydrolase activity
BP422_RS27375	COG0726	polysaccharide deacetylase
BP422_RS27465	COG0010	Belongs to the arginase family
BP422_RS27475	COG1595	DNA-templated transcription, initiation
BP422_RS27480	COG5662	AntiSigma factor
BP422_RS27485	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BP422_RS27495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BP422_RS27500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BP422_RS27540	COG5002	protein histidine kinase activity
BP422_RS27545	COG0745	RESPONSE REGULATOR receiver
BP422_RS27610	COG0833	amino acid
BP422_RS27615	COG2040	homocysteine
BP422_RS27625	COG0584	glycerophosphoryl diester phosphodiesterase
BP422_RS27635	COG0778	Nitroreductase
BP422_RS27640	COG1846	Transcriptional regulator
BP422_RS27650	COG0531	amino acid
BP422_RS27655	COG0697	spore germination
BP422_RS27665	COG2271	Major facilitator Superfamily
BP422_RS27675	COG1733	regulation of RNA biosynthetic process
BP422_RS27685	COG0640	Transcriptional regulator
BP422_RS27690	COG2814	Major facilitator Superfamily
BP422_RS27700	COG0840	transmembrane signaling receptor activity
BP422_RS27705	COG1309	transcriptional regulator
BP422_RS27710	COG2814	Major facilitator Superfamily
BP422_RS27730	COG1113	amino acid transport
BP422_RS27735	COG2322	membrane
BP422_RS27745	COG3173	Aminoglycoside phosphotransferase
BP422_RS27750	COG0708	Exodeoxyribonuclease III
BP422_RS27760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BP422_RS27785	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BP422_RS27790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BP422_RS27795	COG2169	Transcriptional regulator
BP422_RS27805	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BP422_RS27815	COG1309	transcriptional regulator
BP422_RS27835	COG2814	Major facilitator Superfamily
BP422_RS27845	COG2318	DinB family
BP422_RS27850	COG0778	Nitroreductase
BP422_RS27855	COG0346	lactoylglutathione lyase activity
BP422_RS27860	COG0400	carboxylic ester hydrolase activity
BP422_RS27870	COG5002	protein histidine kinase activity
BP422_RS27870	COG3850	Histidine kinase
BP422_RS27910	COG2318	DinB family
BP422_RS27925	COG2207	Transcriptional regulator
BP422_RS27925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS27930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS27935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS27940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BP422_RS27945	COG2819	hydrolase of the alpha beta superfamily
BP422_RS27960	COG3829	transcription factor binding
BP422_RS27960	COG3290	protein histidine kinase activity
BP422_RS27970	COG2610	gluconate transmembrane transporter activity
BP422_RS27975	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS27995	COG0745	RESPONSE REGULATOR receiver
BP422_RS28000	COG5002	protein histidine kinase activity
BP422_RS28005	COG4841	protein insertion into membrane
BP422_RS28015	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS28025	COG4948	Mandelate Racemase Muconate Lactonizing
BP422_RS28030	COG1473	amidohydrolase
BP422_RS28035	COG1288	antiporter activity
BP422_RS28040	COG3290	protein histidine kinase activity
BP422_RS28040	COG3829	transcription factor binding
BP422_RS28050	COG0427	acetyl-CoA hydrolase
BP422_RS28055	COG2814	Major facilitator Superfamily
BP422_RS28060	COG1522	sequence-specific DNA binding
BP422_RS28065	COG1294	oxidase, subunit
BP422_RS28070	COG1271	oxidase subunit
BP422_RS28075	COG1741	Belongs to the pirin family
BP422_RS28080	COG2259	Doxx family
BP422_RS28085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BP422_RS28090	COG1846	Transcriptional regulator
BP422_RS28095	COG1522	sequence-specific DNA binding
BP422_RS28095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BP422_RS28100	COG2313	pseudouridylate synthase activity
BP422_RS28110	COG2217	Heavy metal translocating P-type atpase
BP422_RS28115	COG2608	mercury ion transmembrane transporter activity
BP422_RS28130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BP422_RS28135	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BP422_RS28145	COG2205	protein histidine kinase activity
BP422_RS28165	COG1595	DNA-templated transcription, initiation
BP422_RS28175	COG1971	Probably functions as a manganese efflux pump
BP422_RS28200	COG4585	Histidine kinase
BP422_RS28205	COG2197	response regulator
BP422_RS28215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BP422_RS28220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BP422_RS28225	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS28230	COG0778	Nitroreductase
BP422_RS28235	COG5002	protein histidine kinase activity
BP422_RS28240	COG0745	RESPONSE REGULATOR receiver
BP422_RS28255	COG0523	cobalamin synthesis protein
BP422_RS28285	COG0475	glutathione-regulated potassium exporter activity
BP422_RS28300	COG1522	sequence-specific DNA binding
BP422_RS28305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BP422_RS28320	COG0740	serine-type endopeptidase activity
BP422_RS28330	COG5278	phosphoserine phosphatase activity
BP422_RS28330	COG0840	transmembrane signaling receptor activity
BP422_RS28340	COG4533	DNA binding
BP422_RS28360	COG0583	DNA-binding transcription factor activity
BP422_RS28365	COG2311	Membrane
BP422_RS28370	COG0372	Belongs to the citrate synthase family
BP422_RS28380	COG1902	pentaerythritol trinitrate reductase activity
BP422_RS28385	COG1309	transcriptional regulator
BP422_RS28390	COG0477	Major facilitator Superfamily
BP422_RS28395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS28420	COG4555	ABC transporter
BP422_RS28445	COG0714	Associated with various cellular activities
BP422_RS28450	COG0477	Major facilitator Superfamily
BP422_RS28465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BP422_RS28470	COG1999	signal sequence binding
BP422_RS28485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BP422_RS28500	COG1595	DNA-templated transcription, initiation
BP422_RS28510	COG2814	Major facilitator Superfamily
BP422_RS28515	COG1316	TRANSCRIPTIONal
BP422_RS28550	COG4166	transmembrane transport
BP422_RS28565	COG4166	transmembrane transport
BP422_RS28570	COG4166	transmembrane transport
BP422_RS28575	COG4166	transmembrane transport
BP422_RS28590	COG0860	N-Acetylmuramoyl-L-alanine amidase
BP422_RS28590	COG2247	cell wall binding repeat
BP422_RS28600	COG2155	Conserved Protein
BP422_RS28605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BP422_RS28610	COG0573	inorganic phosphate transmembrane transporter activity
BP422_RS28615	COG0581	inorganic phosphate transmembrane transporter activity
BP422_RS28620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BP422_RS28635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BP422_RS28640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BP422_RS28660	COG0640	Transcriptional regulator
BP422_RS28675	COG0736	holo-[acyl-carrier-protein] synthase activity
BP422_RS28680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BP422_RS28705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BP422_RS28710	COG0864	Transcriptional regulator
BP422_RS28715	COG2337	Toxic component of a toxin-antitoxin (TA) module
BP422_RS28720	COG2172	sigma factor antagonist activity
BP422_RS28725	COG2208	phosphoserine phosphatase activity
BP422_RS28730	COG1366	Belongs to the anti-sigma-factor antagonist family
BP422_RS28735	COG2172	sigma factor antagonist activity
BP422_RS28740	COG1191	sigma factor activity
BP422_RS28745	COG2183	response to ionizing radiation
BP422_RS28760	COG3091	SprT-like family
BP422_RS28765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BP422_RS28770	COG0802	atpase or kinase
BP422_RS28775	COG1214	PFAM Peptidase M22, glycoprotease
BP422_RS28780	COG0456	acetyltransferase
BP422_RS28795	COG1595	DNA-templated transcription, initiation
BP422_RS28805	COG0488	(ABC) transporter
BP422_RS28810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BP422_RS28815	COG0521	Mo-molybdopterin cofactor biosynthetic process
BP422_RS28825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BP422_RS28830	COG0805	protein transport
BP422_RS28840	COG2340	Cysteine-rich secretory protein family
BP422_RS28845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BP422_RS28855	COG0546	phosphoglycolate phosphatase activity
BP422_RS28985	COG0714	Associated with various cellular activities
BP422_RS28995	COG1305	Transglutaminase-like
BP422_RS29010	COG2252	PERMEase
BP422_RS29030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BP422_RS29035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BP422_RS29040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BP422_RS29050	COG1595	DNA-templated transcription, initiation
BP422_RS29060	COG0745	RESPONSE REGULATOR receiver
BP422_RS29065	COG2205	protein histidine kinase activity
BP422_RS29070	COG1136	(ABC) transporter
BP422_RS29075	COG0577	efflux transmembrane transporter activity
BP422_RS29080	COG0590	tRNA wobble adenosine to inosine editing
BP422_RS29090	COG2059	Chromate
BP422_RS29105	COG0405	Gamma-glutamyltransferase
BP422_RS29120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BP422_RS29130	COG5298	Protein conserved in bacteria
BP422_RS29135	COG1215	transferase activity, transferring glycosyl groups
BP422_RS29145	COG2201	protein-glutamate methylesterase activity
BP422_RS29150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BP422_RS29195	COG3279	Response regulator of the LytR AlgR family
BP422_RS29235	COG2304	oxidoreductase activity
BP422_RS29275	COG2304	oxidoreductase activity
BP422_RS29295	COG2378	regulation of single-species biofilm formation
BP422_RS29305	COG1181	Belongs to the D-alanine--D-alanine ligase family
BP422_RS29310	COG1876	peptidase activity
BP422_RS29325	COG2309	aminopeptidase activity
BP422_RS29330	COG1979	alcohol dehydrogenase
BP422_RS29335	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BP422_RS29340	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BP422_RS29345	COG0047	phosphoribosylformylglycinamidine synthase activity
BP422_RS29350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BP422_RS29355	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BP422_RS29360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BP422_RS29365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BP422_RS29385	COG0151	Belongs to the GarS family
BP422_RS29390	COG2814	Major facilitator Superfamily
BP422_RS29395	COG1846	Transcriptional regulator
BP422_RS29405	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BP422_RS29415	COG0559	Belongs to the binding-protein-dependent transport system permease family
BP422_RS29435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS29445	COG1414	Transcriptional regulator
BP422_RS29455	COG3842	ATPase activity
BP422_RS29460	COG1176	ABC-type spermidine putrescine transport system, permease component I
BP422_RS29470	COG2195	Cleaves the N-terminal amino acid of tripeptides
BP422_RS29475	COG0667	Aldo Keto reductase
BP422_RS29480	COG0697	spore germination
BP422_RS29495	COG0531	amino acid
BP422_RS29500	COG0516	GMP reductase activity
BP422_RS29500	COG0517	IMP dehydrogenase activity
BP422_RS29510	COG2205	protein histidine kinase activity
BP422_RS29510	COG2770	Histidine kinase
BP422_RS29515	COG0745	RESPONSE REGULATOR receiver
BP422_RS29520	COG1470	cell adhesion involved in biofilm formation
BP422_RS29525	COG4496	protein, YerC YecD
BP422_RS29530	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BP422_RS29545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BP422_RS29560	COG4753	response regulator
BP422_RS29560	COG2207	Transcriptional regulator
BP422_RS29565	COG2972	Histidine kinase
BP422_RS29585	COG4211	Belongs to the binding-protein-dependent transport system permease family
BP422_RS29595	COG2720	vancomycin resistance protein
BP422_RS29600	COG0210	DNA helicase
BP422_RS29605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BP422_RS29620	COG1012	belongs to the aldehyde dehydrogenase family
BP422_RS29625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BP422_RS29635	COG0688	phosphatidylethanolamine metabolic process
BP422_RS29640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BP422_RS29645	COG0154	amidase activity
BP422_RS29650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BP422_RS29665	COG1595	DNA-templated transcription, initiation
BP422_RS29680	COG4555	ABC transporter
BP422_RS29685	COG1668	transmembrane transport
BP422_RS29690	COG0697	spore germination
BP422_RS29695	COG1940	carbohydrate kinase activity
BP422_RS29700	COG1597	lipid kinase activity
BP422_RS29705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BP422_RS29715	COG1028	Short-chain dehydrogenase reductase Sdr
BP422_RS29780	COG2249	NAD(P)H dehydrogenase (quinone) activity
BP422_RS29785	COG1733	regulation of RNA biosynthetic process
BP422_RS29790	COG3773	Cell wall hydrolase
BP422_RS29800	COG1442	glycosyl transferase family 8
BP422_RS29805	COG1819	glycosyl
BP422_RS29825	COG0133	tryptophan synthase activity
BP422_RS29835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BP422_RS29870	COG2197	response regulator
BP422_RS29880	COG1131	(ABC) transporter
BP422_RS29885	COG0842	Transport permease protein
BP422_RS29885	COG1511	domain protein
BP422_RS29895	COG2972	Histidine kinase
BP422_RS29895	COG0745	RESPONSE REGULATOR receiver
BP422_RS29910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BP422_RS29920	COG1595	DNA-templated transcription, initiation
BP422_RS29930	COG0477	Major facilitator Superfamily
BP422_RS29940	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BP422_RS29955	COG2197	response regulator
BP422_RS29960	COG4585	Histidine kinase
BP422_RS29980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BP422_RS29985	COG1136	(ABC) transporter
BP422_RS30010	COG3239	Fatty acid desaturase
BP422_RS30015	COG4585	Histidine kinase
BP422_RS30020	COG2197	response regulator
BP422_RS30035	COG2807	transmembrane transport
BP422_RS30050	COG5577	PFAM Coat F domain
BP422_RS30060	COG1063	alcohol dehydrogenase
BP422_RS30065	COG5577	PFAM Coat F domain
BP422_RS30075	COG3152	Membrane
BP422_RS30080	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BP422_RS30090	COG0666	response to abiotic stimulus
BP422_RS30100	COG0745	RESPONSE REGULATOR receiver
BP422_RS30110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BP422_RS30115	COG2261	transglycosylase associated protein
BP422_RS30130	COG4166	transmembrane transport
BP422_RS30155	COG1473	amidohydrolase
BP422_RS30160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BP422_RS30180	COG2226	methyltransferase
BP422_RS30195	COG1609	Transcriptional regulator
BP422_RS30200	COG2207	Transcriptional regulator
BP422_RS30200	COG3708	Transcriptional regulator
BP422_RS30215	COG1473	amidohydrolase
BP422_RS30220	COG1288	antiporter activity
BP422_RS30225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BP422_RS30235	COG1132	(ABC) transporter
BP422_RS30240	COG1132	(ABC) transporter
BP422_RS30265	COG0697	spore germination
BP422_RS30270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BP422_RS30300	COG1278	Cold shock
BP422_RS30305	COG1187	pseudouridine synthase activity
BP422_RS30310	COG2258	MOSC domain
BP422_RS30315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BP422_RS30320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BP422_RS30325	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BP422_RS30330	COG1940	carbohydrate kinase activity
BP422_RS30350	COG1346	cytolysis
BP422_RS30360	COG0697	spore germination
BP422_RS30380	COG0840	transmembrane signaling receptor activity
BP422_RS30385	COG0666	response to abiotic stimulus
BP422_RS30390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BP422_RS30400	COG0242	peptide deformylase activity
BP422_RS30410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BP422_RS30415	COG1360	Flagellar Motor Protein
BP422_RS30430	COG1733	regulation of RNA biosynthetic process
BP422_RS30435	COG2267	carboxylic ester hydrolase activity
BP422_RS30440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BP422_RS30445	COG3852	Histidine kinase
BP422_RS30450	COG2204	response regulator
BP422_RS30455	COG2031	fatty acid transporter
BP422_RS30460	COG2076	Multidrug Resistance protein
BP422_RS30465	COG2076	Multidrug Resistance protein
BP422_RS30475	COG1253	flavin adenine dinucleotide binding
BP422_RS30510	COG0577	efflux transmembrane transporter activity
BP422_RS30515	COG1136	(ABC) transporter
BP422_RS30520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BP422_RS30525	COG0166	Belongs to the GPI family
BP422_RS30530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BP422_RS30545	COG0494	nUDIX hydrolase
BP422_RS30550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BP422_RS30560	COG0442	prolyl-tRNA aminoacylation
BP422_RS30570	COG1247	-acetyltransferase
BP422_RS30585	COG0004	ammonium transporteR
BP422_RS30595	COG2814	Major facilitator Superfamily
BP422_RS30600	COG0640	Transcriptional regulator
BP422_RS30605	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BP422_RS30620	COG2996	Protein conserved in bacteria
BP422_RS30635	COG2358	TRAP transporter, solute receptor (TAXI family
BP422_RS30640	COG4191	Histidine kinase
BP422_RS30645	COG0784	Response regulator, receiver
BP422_RS30665	COG2133	pyrroloquinoline quinone binding
BP422_RS30690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BP422_RS30695	COG1114	Component of the transport system for branched-chain amino acids
BP422_RS30700	COG0745	RESPONSE REGULATOR receiver
BP422_RS30705	COG5002	protein histidine kinase activity
BP422_RS30705	COG3850	Histidine kinase
BP422_RS30720	COG0697	spore germination
BP422_RS30735	COG0824	Thioesterase
BP422_RS30765	COG0745	RESPONSE REGULATOR receiver
BP422_RS30770	COG2205	protein histidine kinase activity
BP422_RS30800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BP422_RS30810	COG1742	UPF0060 membrane protein
BP422_RS30820	COG3192	ethanolamine utilization protein
BP422_RS30835	COG0346	lactoylglutathione lyase activity
BP422_RS30845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BP422_RS30850	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BP422_RS30855	COG2032	superoxide dismutase activity
BP422_RS30860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BP422_RS30870	COG1595	DNA-templated transcription, initiation