locus-tag	class	description
C0R09_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0R09_RS00010	COG0592	DNA-directed DNA polymerase activity
C0R09_RS00015	COG2501	S4 domain
C0R09_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C0R09_RS00030	COG0187	DNA topoisomerase II activity
C0R09_RS00040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0R09_RS00045	COG0180	Tryptophanyl-tRNA synthetase
C0R09_RS00055	COG1136	(ABC) transporter
C0R09_RS00060	COG0577	efflux transmembrane transporter activity
C0R09_RS00065	COG4106	trans-aconitate 2-methyltransferase activity
C0R09_RS00070	COG2267	carboxylic ester hydrolase activity
C0R09_RS00075	COG0156	8-amino-7-oxononanoate synthase activity
C0R09_RS00080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C0R09_RS00090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0R09_RS00100	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0R09_RS00105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C0R09_RS00135	COG0517	IMP dehydrogenase activity
C0R09_RS00135	COG0516	GMP reductase activity
C0R09_RS00145	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C0R09_RS00150	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C0R09_RS00160	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0R09_RS00165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C0R09_RS00170	COG2224	Isocitrate lyase
C0R09_RS00185	COG1191	sigma factor activity
C0R09_RS00195	COG0590	tRNA wobble adenosine to inosine editing
C0R09_RS00200	COG1187	pseudouridine synthase activity
C0R09_RS00210	COG3852	Histidine kinase
C0R09_RS00215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C0R09_RS00220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C0R09_RS00225	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C0R09_RS00265	COG1982	Orn Lys Arg decarboxylase major
C0R09_RS00275	COG3870	Protein conserved in bacteria
C0R09_RS00280	COG1728	Protein conserved in bacteria
C0R09_RS00285	COG0470	DNA polymerase III
C0R09_RS00290	COG1774	PSP1 C-terminal conserved region
C0R09_RS00295	COG4467	Involved in initiation control of chromosome replication
C0R09_RS00300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C0R09_RS00305	COG2827	Endonuclease containing a URI domain
C0R09_RS00310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C0R09_RS00315	COG2002	toxin-antitoxin pair type II binding
C0R09_RS00320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0R09_RS00320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0R09_RS00325	COG0084	hydrolase, TatD family'
C0R09_RS00335	COG3584	3D domain protein
C0R09_RS00335	COG1388	LysM domain
C0R09_RS00345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C0R09_RS00350	COG4466	Protein conserved in bacteria
C0R09_RS00360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C0R09_RS00365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0R09_RS00370	COG2088	sporulation resulting in formation of a cellular spore
C0R09_RS00380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C0R09_RS00385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0R09_RS00390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C0R09_RS00395	COG0193	aminoacyl-tRNA hydrolase activity
C0R09_RS00405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C0R09_RS00415	COG2002	toxin-antitoxin pair type II binding
C0R09_RS00420	COG2244	polysaccharide biosynthetic process
C0R09_RS00425	COG3956	TIGRFAM MazG family protein
C0R09_RS00430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C0R09_RS00450	COG2208	phosphoserine phosphatase activity
C0R09_RS00455	COG2304	oxidoreductase activity
C0R09_RS00460	COG0515	serine threonine protein kinase
C0R09_RS00480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C0R09_RS00485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0R09_RS00490	COG0561	phosphatase activity
C0R09_RS00495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C0R09_RS00505	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0R09_RS00515	COG1121	(ABC) transporter
C0R09_RS00520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0R09_RS00525	COG0735	belongs to the Fur family
C0R09_RS00535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C0R09_RS00545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C0R09_RS00565	COG2894	cell division
C0R09_RS00625	COG1595	DNA-templated transcription, initiation
C0R09_RS00635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0R09_RS00640	COG1733	regulation of RNA biosynthetic process
C0R09_RS00645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C0R09_RS00650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0R09_RS00655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0R09_RS00660	COG0512	Glutamine amidotransferase of anthranilate synthase
C0R09_RS00665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0R09_RS00670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C0R09_RS00675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C0R09_RS00680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0R09_RS00685	COG1396	sequence-specific DNA binding
C0R09_RS00690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0R09_RS00695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0R09_RS00745	COG3880	PFAM UvrB UvrC protein
C0R09_RS00750	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C0R09_RS00755	COG0542	response to heat
C0R09_RS00760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C0R09_RS00765	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C0R09_RS00770	COG1183	phosphatidylcholine synthase activity
C0R09_RS00780	COG4956	integral membrane protein (PIN domain superfamily)
C0R09_RS00790	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C0R09_RS00795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0R09_RS00800	COG1045	serine acetyltransferase
C0R09_RS00805	COG0215	cysteine-tRNA ligase activity
C0R09_RS00810	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C0R09_RS00815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0R09_RS00820	COG3688	RNA-binding protein containing a PIN domain
C0R09_RS00830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0R09_RS00835	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0R09_RS00840	COG0250	Participates in transcription elongation, termination and antitermination
C0R09_RS00845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C0R09_RS00850	COG0081	regulation of translation
C0R09_RS00855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C0R09_RS00860	COG0222	ribosome binding
C0R09_RS00865	COG2813	Specifically methylates the guanine in position
C0R09_RS00870	COG0085	RNA polymerase activity
C0R09_RS00875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C0R09_RS00880	COG1358	cellular component organization or biogenesis
C0R09_RS00885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C0R09_RS00890	COG0049	tRNA binding
C0R09_RS00895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C0R09_RS00900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0R09_RS00910	COG2346	COG2346, Truncated hemoglobins
C0R09_RS00920	COG0051	transcription antitermination factor activity, RNA binding
C0R09_RS00925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C0R09_RS00930	COG0088	Forms part of the polypeptide exit tunnel
C0R09_RS00935	COG0089	rRNA binding
C0R09_RS00940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0R09_RS00945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C0R09_RS00950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C0R09_RS00955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C0R09_RS00960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C0R09_RS00965	COG0255	Belongs to the universal ribosomal protein uL29 family
C0R09_RS00970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C0R09_RS00975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C0R09_RS00980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C0R09_RS00985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C0R09_RS00990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C0R09_RS00995	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C0R09_RS01000	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C0R09_RS01005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C0R09_RS01010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C0R09_RS01015	COG1841	ribosomal large subunit assembly
C0R09_RS01020	COG0200	Binds to the 23S rRNA
C0R09_RS01025	COG0201	protein transport
C0R09_RS01030	COG0563	adenylate kinase activity
C0R09_RS01035	COG0024	Methionine aminopeptidase
C0R09_RS01040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0R09_RS01045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0R09_RS01050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0R09_RS01055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C0R09_RS01060	COG0202	RNA polymerase activity
C0R09_RS01065	COG0203	ribosomal protein L17
C0R09_RS01070	COG1122	ATPase activity
C0R09_RS01075	COG1122	ATPase activity
C0R09_RS01080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C0R09_RS01085	COG0101	tRNA pseudouridine synthase activity
C0R09_RS01090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C0R09_RS01095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C0R09_RS01105	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0R09_RS01110	COG0489	protein tyrosine kinase activity
C0R09_RS01125	COG2194	sulfuric ester hydrolase activity
C0R09_RS01130	COG0726	polysaccharide deacetylase
C0R09_RS01220	COG0010	Belongs to the arginase family
C0R09_RS01230	COG1595	DNA-templated transcription, initiation
C0R09_RS01235	COG5662	AntiSigma factor
C0R09_RS01240	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C0R09_RS01245	COG4856	YbbR-like protein
C0R09_RS01250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0R09_RS01360	COG0827	DNA restriction-modification system
C0R09_RS01405	COG0583	DNA-binding transcription factor activity
C0R09_RS01415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0R09_RS01420	COG0523	cobalamin synthesis protein
C0R09_RS01440	COG0372	Belongs to the citrate synthase family
C0R09_RS01445	COG2079	MmgE PrpD family protein
C0R09_RS01450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C0R09_RS01460	COG1960	acyl-CoA dehydrogenase activity
C0R09_RS01470	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS01500	COG1309	transcriptional regulator
C0R09_RS01520	COG2211	Major facilitator Superfamily
C0R09_RS01525	COG0475	glutathione-regulated potassium exporter activity
C0R09_RS01540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0R09_RS01540	COG1328	CTP reductase activity
C0R09_RS01550	COG0243	molybdopterin cofactor binding
C0R09_RS01560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS01560	COG2207	Transcriptional regulator
C0R09_RS01565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS01570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS01575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS01580	COG2259	Doxx family
C0R09_RS01590	COG0745	RESPONSE REGULATOR receiver
C0R09_RS01595	COG5002	protein histidine kinase activity
C0R09_RS01620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0R09_RS01630	COG0586	Pfam SNARE associated Golgi protein
C0R09_RS01640	COG1132	(ABC) transporter
C0R09_RS01645	COG1132	(ABC) transporter
C0R09_RS01650	COG2311	Membrane
C0R09_RS01655	COG0577	efflux transmembrane transporter activity
C0R09_RS01660	COG1136	(ABC) transporter
C0R09_RS01665	COG2602	Beta-lactamase
C0R09_RS01675	COG0768	penicillin binding
C0R09_RS01685	COG1414	Transcriptional regulator
C0R09_RS01690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C0R09_RS01710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C0R09_RS01715	COG1984	allophanate hydrolase subunit 2
C0R09_RS01720	COG5583	Uncharacterized small protein (DUF2292)
C0R09_RS01725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0R09_RS01730	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C0R09_RS01735	COG4208	sulfate ABC transporter
C0R09_RS01740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0R09_RS01745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS01750	COG0673	inositol 2-dehydrogenase activity
C0R09_RS01755	COG0589	response to stress
C0R09_RS01760	COG0500	methyltransferase
C0R09_RS01765	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0R09_RS01770	COG1937	Protein conserved in bacteria
C0R09_RS01775	COG0733	neurotransmitter:sodium symporter activity
C0R09_RS01780	COG0783	Belongs to the Dps family
C0R09_RS01790	COG2190	(PTS) system
C0R09_RS01790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0R09_RS01790	COG1263	PTS System
C0R09_RS01810	COG2258	MOSC domain
C0R09_RS01825	COG1914	H( )-stimulated, divalent metal cation uptake system
C0R09_RS01830	COG0288	reversible hydration of carbon dioxide
C0R09_RS01835	COG4166	transmembrane transport
C0R09_RS01840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0R09_RS01845	COG0746	molybdenum cofactor guanylyltransferase activity
C0R09_RS01850	COG1763	Mo-molybdopterin cofactor biosynthetic process
C0R09_RS01860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C0R09_RS01865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C0R09_RS01875	COG2205	protein histidine kinase activity
C0R09_RS01885	COG5609	conserved protein (DUF2294)
C0R09_RS01970	COG0681	Belongs to the peptidase S26 family
C0R09_RS01975	COG4585	Histidine kinase
C0R09_RS01980	COG2197	response regulator
C0R09_RS02000	COG2070	2-Nitropropane dioxygenase
C0R09_RS02005	COG0583	DNA-binding transcription factor activity
C0R09_RS02010	COG0372	Belongs to the citrate synthase family
C0R09_RS02015	COG4585	Histidine kinase
C0R09_RS02020	COG2197	response regulator
C0R09_RS02050	COG1271	oxidase subunit
C0R09_RS02055	COG1294	oxidase, subunit
C0R09_RS02060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0R09_RS02075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C0R09_RS02080	COG0573	inorganic phosphate transmembrane transporter activity
C0R09_RS02085	COG0581	inorganic phosphate transmembrane transporter activity
C0R09_RS02095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C0R09_RS02105	COG1971	Probably functions as a manganese efflux pump
C0R09_RS02110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0R09_RS02120	COG1316	TRANSCRIPTIONal
C0R09_RS02125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C0R09_RS02130	COG2011	ABC-type metal ion transport system permease component
C0R09_RS02135	COG1464	Belongs to the NlpA lipoprotein family
C0R09_RS02145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0R09_RS02150	COG4166	transmembrane transport
C0R09_RS02155	COG4166	transmembrane transport
C0R09_RS02180	COG2155	Conserved Protein
C0R09_RS02185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0R09_RS02190	COG0640	Transcriptional regulator
C0R09_RS02200	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C0R09_RS02210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0R09_RS02215	COG0864	Transcriptional regulator
C0R09_RS02220	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0R09_RS02225	COG2183	response to ionizing radiation
C0R09_RS02240	COG3091	SprT-like family
C0R09_RS02245	COG0802	atpase or kinase
C0R09_RS02250	COG1214	PFAM Peptidase M22, glycoprotease
C0R09_RS02255	COG0456	acetyltransferase
C0R09_RS02270	COG0488	(ABC) transporter
C0R09_RS02275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0R09_RS02280	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0R09_RS02290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0R09_RS02295	COG0805	protein transport
C0R09_RS02300	COG0670	Belongs to the BI1 family
C0R09_RS02310	COG2340	Cysteine-rich secretory protein family
C0R09_RS02315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C0R09_RS02440	COG0714	Associated with various cellular activities
C0R09_RS02445	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C0R09_RS02450	COG1305	Transglutaminase-like
C0R09_RS02460	COG2252	PERMEase
C0R09_RS02465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C0R09_RS02470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C0R09_RS02475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C0R09_RS02480	COG2309	aminopeptidase activity
C0R09_RS02485	COG1979	alcohol dehydrogenase
C0R09_RS02490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C0R09_RS02495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0R09_RS02500	COG0047	phosphoribosylformylglycinamidine synthase activity
C0R09_RS02510	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C0R09_RS02515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0R09_RS02520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0R09_RS02530	COG0840	transmembrane signaling receptor activity
C0R09_RS02540	COG0702	epimerase
C0R09_RS02550	COG0151	Belongs to the GarS family
C0R09_RS02560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C0R09_RS02570	COG0559	Belongs to the binding-protein-dependent transport system permease family
C0R09_RS02590	COG3858	chitin binding
C0R09_RS02595	COG2770	Histidine kinase
C0R09_RS02595	COG2205	protein histidine kinase activity
C0R09_RS02600	COG0745	RESPONSE REGULATOR receiver
C0R09_RS02605	COG1470	cell adhesion involved in biofilm formation
C0R09_RS02610	COG4496	protein, YerC YecD
C0R09_RS02615	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C0R09_RS02620	COG0210	DNA helicase
C0R09_RS02625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0R09_RS02640	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS02655	COG0688	phosphatidylethanolamine metabolic process
C0R09_RS02665	COG1595	DNA-templated transcription, initiation
C0R09_RS02670	COG1307	EDD domain protein, DegV family
C0R09_RS02680	COG0154	amidase activity
C0R09_RS02685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C0R09_RS02690	COG2211	Major facilitator Superfamily
C0R09_RS02700	COG1136	(ABC) transporter
C0R09_RS02705	COG0577	efflux transmembrane transporter activity
C0R09_RS02730	COG4555	ABC transporter
C0R09_RS02745	COG4555	ABC transporter
C0R09_RS02750	COG1668	transmembrane transport
C0R09_RS02755	COG1940	carbohydrate kinase activity
C0R09_RS02760	COG1597	lipid kinase activity
C0R09_RS02765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0R09_RS02855	COG1819	glycosyl
C0R09_RS02890	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS02945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS02955	COG0840	transmembrane signaling receptor activity
C0R09_RS02970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS02975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS02980	COG0733	neurotransmitter:sodium symporter activity
C0R09_RS02990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0R09_RS03005	COG2226	methyltransferase
C0R09_RS03015	COG1132	(ABC) transporter
C0R09_RS03015	COG2375	cellular response to nickel ion
C0R09_RS03035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0R09_RS03040	COG1131	(ABC) transporter
C0R09_RS03075	COG0028	Belongs to the TPP enzyme family
C0R09_RS03095	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS03100	COG0454	-acetyltransferase
C0R09_RS03110	COG1988	membrane-bound metal-dependent
C0R09_RS03115	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
C0R09_RS03120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C0R09_RS03125	COG2066	Belongs to the glutaminase family
C0R09_RS03145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS03150	COG1742	UPF0060 membrane protein
C0R09_RS03160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0R09_RS03165	COG0833	amino acid
C0R09_RS03170	COG3829	transcription factor binding
C0R09_RS03175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0R09_RS03185	COG1595	DNA-templated transcription, initiation
C0R09_RS03190	COG0656	L-ascorbic acid biosynthetic process
C0R09_RS03205	COG0720	synthase
C0R09_RS03215	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C0R09_RS03220	COG0805	protein transport
C0R09_RS03225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0R09_RS03240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C0R09_RS03250	COG0351	phosphomethylpyrimidine kinase
C0R09_RS03285	COG1694	Mazg nucleotide pyrophosphohydrolase
C0R09_RS03310	COG3876	Protein conserved in bacteria
C0R09_RS03315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0R09_RS03320	COG1360	Flagellar Motor Protein
C0R09_RS03325	COG1279	arginine transmembrane transporter activity
C0R09_RS03330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0R09_RS03335	COG4844	belongs to the
C0R09_RS03370	COG0577	efflux transmembrane transporter activity
C0R09_RS03375	COG1136	(ABC) transporter
C0R09_RS03380	COG1566	PFAM secretion protein HlyD family protein
C0R09_RS03385	COG0166	Belongs to the GPI family
C0R09_RS03390	COG0166	Belongs to the GPI family
C0R09_RS03395	COG2022	thiamine diphosphate biosynthetic process
C0R09_RS03395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0R09_RS03405	COG3858	chitin binding
C0R09_RS03415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0R09_RS03445	COG1968	undecaprenyl-diphosphatase activity
C0R09_RS03450	COG2996	Protein conserved in bacteria
C0R09_RS03455	COG2124	cytochrome p450
C0R09_RS03460	COG1309	transcriptional regulator
C0R09_RS03470	COG1725	Transcriptional regulator
C0R09_RS03475	COG1131	(ABC) transporter
C0R09_RS03485	COG3290	protein histidine kinase activity
C0R09_RS03485	COG3829	transcription factor binding
C0R09_RS03510	COG0824	Thioesterase
C0R09_RS03515	COG2814	Major facilitator Superfamily
C0R09_RS03520	COG1794	racemase activity, acting on amino acids and derivatives
C0R09_RS03525	COG0697	spore germination
C0R09_RS03540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C0R09_RS03555	COG0488	(ABC) transporter
C0R09_RS03560	COG0564	pseudouridine synthase activity
C0R09_RS03570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0R09_RS03575	COG2076	Multidrug Resistance protein
C0R09_RS03580	COG2076	Multidrug Resistance protein
C0R09_RS03585	COG1309	transcriptional regulator
C0R09_RS03600	COG5002	protein histidine kinase activity
C0R09_RS03605	COG0745	RESPONSE REGULATOR receiver
C0R09_RS03610	COG0791	NLP P60 protein
C0R09_RS03620	COG1842	Phage shock protein A
C0R09_RS03630	COG4758	membrane
C0R09_RS03635	COG4585	Histidine kinase
C0R09_RS03640	COG2197	response regulator
C0R09_RS03645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0R09_RS03665	COG0730	response to heat
C0R09_RS03675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C0R09_RS03680	COG1988	membrane-bound metal-dependent
C0R09_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS03695	COG0456	acetyltransferase
C0R09_RS03700	COG3557	Belongs to the UPF0374 family
C0R09_RS03710	COG1132	(ABC) transporter
C0R09_RS03725	COG2738	Putative neutral zinc metallopeptidase
C0R09_RS03730	COG0067	glutamate synthase
C0R09_RS03730	COG0069	glutamate synthase activity
C0R09_RS03730	COG0070	glutamate synthase
C0R09_RS03735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C0R09_RS03740	COG4555	ABC transporter
C0R09_RS03755	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C0R09_RS03760	COG0546	phosphoglycolate phosphatase activity
C0R09_RS03770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0R09_RS03775	COG1363	Peptidase, m42
C0R09_RS03780	COG2226	methyltransferase
C0R09_RS03785	COG2096	Adenosyltransferase
C0R09_RS03790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0R09_RS03795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0R09_RS03800	COG0735	belongs to the Fur family
C0R09_RS03895	COG2233	PERMEase
C0R09_RS03905	COG0328	RNA-DNA hybrid ribonuclease activity
C0R09_RS03910	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0R09_RS03915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0R09_RS03940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0R09_RS03960	COG0456	acetyltransferase
C0R09_RS03970	COG4626	Terminase
C0R09_RS03970	COG1802	Transcriptional regulator
C0R09_RS03975	COG1720	tRNA m6t6A37 methyltransferase activity
C0R09_RS04045	COG2718	Belongs to the UPF0229 family
C0R09_RS04110	COG0737	Belongs to the 5'-nucleotidase family
C0R09_RS04120	COG2267	carboxylic ester hydrolase activity
C0R09_RS04125	COG3314	Sporulation integral membrane protein YlbJ
C0R09_RS04130	COG2244	polysaccharide biosynthetic process
C0R09_RS04135	COG0693	protein deglycase activity
C0R09_RS04140	COG0697	spore germination
C0R09_RS04160	COG2423	ornithine cyclodeaminase activity
C0R09_RS04165	COG2719	SpoVR family
C0R09_RS04170	COG3290	protein histidine kinase activity
C0R09_RS04175	COG4565	transcriptional regulatory protein
C0R09_RS04185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0R09_RS04200	COG0745	RESPONSE REGULATOR receiver
C0R09_RS04205	COG5002	protein histidine kinase activity
C0R09_RS04215	COG1136	(ABC) transporter
C0R09_RS04220	COG1136	(ABC) transporter
C0R09_RS04220	COG0577	efflux transmembrane transporter activity
C0R09_RS04235	COG0277	FAD linked oxidase domain protein
C0R09_RS04245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS04250	COG0583	DNA-binding transcription factor activity
C0R09_RS04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS04285	COG1349	DNA-binding transcription factor activity
C0R09_RS04290	COG1105	Belongs to the carbohydrate kinase PfkB family
C0R09_RS04295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0R09_RS04295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0R09_RS04295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS04300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS04325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0R09_RS04335	COG1082	Xylose isomerase domain protein TIM barrel
C0R09_RS04340	COG3693	PFAM glycoside hydrolase, family 10
C0R09_RS04345	COG0640	Transcriptional regulator
C0R09_RS04350	COG2363	Small membrane protein
C0R09_RS04355	COG1272	protein, Hemolysin III
C0R09_RS04360	COG0513	Belongs to the DEAD box helicase family
C0R09_RS04380	COG5002	protein histidine kinase activity
C0R09_RS04385	COG2855	membrane
C0R09_RS04425	COG0189	ligase activity
C0R09_RS04430	COG0189	ligase activity
C0R09_RS04440	COG4399	Belongs to the UPF0754 family
C0R09_RS04445	COG1757	Na H antiporter
C0R09_RS04460	COG3679	Belongs to the UPF0342 family
C0R09_RS04465	COG4109	DRTGG domain
C0R09_RS04480	COG0587	DNA-directed DNA polymerase activity
C0R09_RS04485	COG0281	malic enzyme
C0R09_RS04490	COG2186	Transcriptional regulator
C0R09_RS04500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C0R09_RS04505	COG0825	malonyl-CoA metabolic process
C0R09_RS04510	COG0205	6-phosphofructokinase activity
C0R09_RS04520	COG0824	Thioesterase
C0R09_RS04530	COG0628	permease
C0R09_RS04535	COG0372	Belongs to the citrate synthase family
C0R09_RS04540	COG0538	isocitrate dehydrogenase activity
C0R09_RS04545	COG0039	L-malate dehydrogenase activity
C0R09_RS04550	COG0745	RESPONSE REGULATOR receiver
C0R09_RS04555	COG5002	protein histidine kinase activity
C0R09_RS04560	COG2720	vancomycin resistance protein
C0R09_RS04565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0R09_RS04575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0R09_RS04575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0R09_RS04580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0R09_RS04590	COG1196	nuclear chromosome segregation
C0R09_RS04590	COG0741	lytic transglycosylase activity
C0R09_RS04590	COG0739	heme binding
C0R09_RS04595	COG2207	Transcriptional regulator
C0R09_RS04600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0R09_RS04605	COG3693	PFAM glycoside hydrolase, family 10
C0R09_RS04620	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0R09_RS04630	COG1484	DNA-dependent DNA replication
C0R09_RS04640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0R09_RS04650	COG2207	Transcriptional regulator
C0R09_RS04660	COG3397	chitin binding
C0R09_RS04665	COG3397	chitin binding
C0R09_RS04670	COG2188	Transcriptional regulator
C0R09_RS04680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0R09_RS04680	COG1263	PTS System
C0R09_RS04685	COG0366	Alpha amylase catalytic
C0R09_RS04695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS04725	COG1129	ABC transporter
C0R09_RS04725	COG0842	Transport permease protein
C0R09_RS04735	COG0667	Aldo Keto reductase
C0R09_RS04740	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS04740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS04740	COG0300	oxidoreductase activity
C0R09_RS04740	COG3321	synthase
C0R09_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS04810	COG0210	DNA helicase
C0R09_RS04840	COG0840	transmembrane signaling receptor activity
C0R09_RS04845	COG0490	domain, Protein
C0R09_RS04850	COG0475	glutathione-regulated potassium exporter activity
C0R09_RS04865	COG1595	DNA-templated transcription, initiation
C0R09_RS04880	COG0745	RESPONSE REGULATOR receiver
C0R09_RS04885	COG2205	protein histidine kinase activity
C0R09_RS04915	COG0656	L-ascorbic acid biosynthetic process
C0R09_RS04920	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS04925	COG1846	Transcriptional regulator
C0R09_RS04960	COG2267	carboxylic ester hydrolase activity
C0R09_RS04965	COG0697	spore germination
C0R09_RS04975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0R09_RS04990	COG1144	Oxidoreductase
C0R09_RS04995	COG0674	pyruvate-flavodoxin oxidoreductase activity
C0R09_RS05000	COG1268	BioY protein
C0R09_RS05025	COG0814	amino acid
C0R09_RS05030	COG0697	spore germination
C0R09_RS05035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS05040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS05045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS05055	COG3976	FMN-binding domain protein
C0R09_RS05055	COG1053	succinate dehydrogenase
C0R09_RS05070	COG0561	phosphatase activity
C0R09_RS05075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0R09_RS05080	COG2146	nitrite reductase [NAD(P)H] activity
C0R09_RS05090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C0R09_RS05100	COG3711	transcriptional antiterminator
C0R09_RS05110	COG0246	Mannitol dehydrogenase
C0R09_RS05115	COG1509	lysine 2,3-aminomutase activity
C0R09_RS05125	COG2814	Major facilitator Superfamily
C0R09_RS05130	COG1164	Oligoendopeptidase f
C0R09_RS05135	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0R09_RS05140	COG2204	response regulator
C0R09_RS05145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0R09_RS05150	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS05170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0R09_RS05170	COG2010	Cytochrome c
C0R09_RS05175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0R09_RS05190	COG3336	cytochrome c oxidase
C0R09_RS05205	COG3773	Cell wall hydrolase
C0R09_RS05210	COG0531	amino acid
C0R09_RS05230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C0R09_RS05240	COG1252	NADH dehydrogenase
C0R09_RS05250	COG0142	geranyltranstransferase activity
C0R09_RS05265	COG1396	sequence-specific DNA binding
C0R09_RS05275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C0R09_RS05280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0R09_RS05285	COG0826	peptidase U32
C0R09_RS05290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C0R09_RS05300	COG1122	ATPase activity
C0R09_RS05325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C0R09_RS05330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0R09_RS05335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C0R09_RS05340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0R09_RS05345	COG0626	cystathionine gamma-synthase activity
C0R09_RS05350	COG0626	cystathionine gamma-synthase activity
C0R09_RS05360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0R09_RS05365	COG0175	sulfate reduction
C0R09_RS05370	COG2046	Belongs to the sulfate adenylyltransferase family
C0R09_RS05375	COG0028	Belongs to the TPP enzyme family
C0R09_RS05380	COG0440	acetolactate synthase activity
C0R09_RS05385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C0R09_RS05390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0R09_RS05400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0R09_RS05410	COG1741	Belongs to the pirin family
C0R09_RS05415	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0R09_RS05425	COG0586	Pfam SNARE associated Golgi protein
C0R09_RS05435	COG1363	Peptidase, m42
C0R09_RS05445	COG0569	domain protein
C0R09_RS05450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0R09_RS05455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0R09_RS05465	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C0R09_RS05475	COG1193	negative regulation of DNA recombination
C0R09_RS05480	COG3766	membrane
C0R09_RS05485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C0R09_RS05490	COG2362	D-Aminopeptidase
C0R09_RS05495	COG0438	transferase activity, transferring glycosyl groups
C0R09_RS05520	COG0728	peptidoglycan biosynthetic process
C0R09_RS05535	COG0515	serine threonine protein kinase
C0R09_RS05535	COG3266	domain, Protein
C0R09_RS05555	COG0484	heat shock protein binding
C0R09_RS05630	COG3196	Protein conserved in bacteria
C0R09_RS05645	COG1595	DNA-templated transcription, initiation
C0R09_RS05655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS05660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS05665	COG1120	ATPase activity
C0R09_RS05670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0R09_RS05680	COG2264	protein methyltransferase activity
C0R09_RS05690	COG1316	TRANSCRIPTIONal
C0R09_RS05695	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS05700	COG1309	transcriptional regulator
C0R09_RS05705	COG1024	Enoyl-CoA hydratase
C0R09_RS05710	COG2086	electron transfer activity
C0R09_RS05715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C0R09_RS05725	COG3118	belongs to the thioredoxin family
C0R09_RS05730	COG0322	excinuclease ABC activity
C0R09_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS05750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0R09_RS05765	COG2009	succinate dehydrogenase
C0R09_RS05770	COG1053	succinate dehydrogenase
C0R09_RS05775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0R09_RS05790	COG2822	iron ion transport
C0R09_RS05795	COG2837	iron assimilation
C0R09_RS05800	COG0672	)-iron permease
C0R09_RS05805	COG3711	transcriptional antiterminator
C0R09_RS05810	COG2190	(PTS) system
C0R09_RS05810	COG1263	PTS System
C0R09_RS05810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0R09_RS05815	COG2723	6-phospho-beta-galactosidase activity
C0R09_RS05825	COG2197	response regulator
C0R09_RS05830	COG3859	Proton-coupled thiamine transporter YuaJ
C0R09_RS05835	COG2169	Transcriptional regulator
C0R09_RS05870	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
C0R09_RS05900	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C0R09_RS05905	COG1492	cobalamin metabolic process
C0R09_RS05910	COG0310	cobalt ion transport
C0R09_RS05915	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
C0R09_RS05925	COG1122	ATPase activity
C0R09_RS05930	COG0776	regulation of translation
C0R09_RS05935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0R09_RS05940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C0R09_RS05945	COG0789	Transcriptional regulator
C0R09_RS05950	COG2814	Major facilitator Superfamily
C0R09_RS05955	COG5401	PFAM Sporulation and spore germination
C0R09_RS05960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C0R09_RS05965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C0R09_RS05970	COG0622	Phosphoesterase
C0R09_RS05975	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0R09_RS05980	COG0740	serine-type endopeptidase activity
C0R09_RS05985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C0R09_RS05990	COG1067	ATP-dependent peptidase activity
C0R09_RS05990	COG0470	DNA polymerase III
C0R09_RS06000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C0R09_RS06005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C0R09_RS06015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C0R09_RS06020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0R09_RS06025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0R09_RS06025	COG1648	precorrin-2 dehydrogenase activity
C0R09_RS06030	COG0181	hydroxymethylbilane synthase activity
C0R09_RS06035	COG1587	Uroporphyrinogen-III synthase
C0R09_RS06035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0R09_RS06040	COG0113	porphobilinogen synthase activity
C0R09_RS06045	COG1522	sequence-specific DNA binding
C0R09_RS06050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C0R09_RS06070	COG1388	LysM domain
C0R09_RS06090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0R09_RS06095	COG0525	valine-tRNA ligase activity
C0R09_RS06100	COG0285	dihydrofolate synthase activity
C0R09_RS06105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0R09_RS06110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C0R09_RS06125	COG0424	maF-like protein
C0R09_RS06130	COG2003	Belongs to the UPF0758 family
C0R09_RS06135	COG1077	Cell shape determining protein MreB Mrl
C0R09_RS06140	COG1792	Involved in formation and maintenance of cell shape
C0R09_RS06150	COG0768	penicillin binding
C0R09_RS06155	COG0850	regulation of cytokinetic process
C0R09_RS06160	COG2894	cell division
C0R09_RS06165	COG0772	Belongs to the SEDS family
C0R09_RS06170	COG1278	Cold shock
C0R09_RS06180	COG1994	Peptidase M50
C0R09_RS06190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C0R09_RS06195	COG2868	ribosomal protein
C0R09_RS06200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C0R09_RS06210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C0R09_RS06220	COG4492	Belongs to the UPF0735 family
C0R09_RS06225	COG0460	homoserine dehydrogenase
C0R09_RS06230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0R09_RS06235	COG0083	homoserine kinase activity
C0R09_RS06240	COG0077	Prephenate dehydratase
C0R09_RS06245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0R09_RS06260	COG0584	glycerophosphoryl diester phosphodiesterase
C0R09_RS06280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0R09_RS06300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0R09_RS06305	COG0632	four-way junction helicase activity
C0R09_RS06310	COG2255	four-way junction helicase activity
C0R09_RS06315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C0R09_RS06325	COG1862	Preprotein translocase
C0R09_RS06335	COG0598	Magnesium transport protein CorA
C0R09_RS06340	COG2323	membrane
C0R09_RS06345	COG2244	polysaccharide biosynthetic process
C0R09_RS06355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0R09_RS06355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0R09_RS06360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0R09_RS06365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C0R09_RS06370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C0R09_RS06370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0R09_RS06375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0R09_RS06380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0R09_RS06385	COG1490	D-aminoacyl-tRNA deacylase activity
C0R09_RS06390	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0R09_RS06390	COG3103	Sh3 type 3 domain protein
C0R09_RS06390	COG4991	sh3 domain protein
C0R09_RS06395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0R09_RS06400	COG0124	histidyl-tRNA synthetase
C0R09_RS06405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C0R09_RS06410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0R09_RS06420	COG1959	2 iron, 2 sulfur cluster binding
C0R09_RS06425	COG1104	cysteine desulfurase activity
C0R09_RS06430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C0R09_RS06445	COG0628	permease
C0R09_RS06455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0R09_RS06460	COG4472	Bacterial protein of unknown function (DUF965)
C0R09_RS06470	COG3906	Belongs to the UPF0473 family
C0R09_RS06485	COG4122	O-methyltransferase activity
C0R09_RS06490	COG0826	peptidase U32
C0R09_RS06495	COG0826	peptidase U32
C0R09_RS06500	COG0572	uridine kinase
C0R09_RS06505	COG0768	penicillin binding
C0R09_RS06520	COG0733	neurotransmitter:sodium symporter activity
C0R09_RS06530	COG2824	Alkylphosphonate utilization operon protein PhnA
C0R09_RS06535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0R09_RS06565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C0R09_RS06565	COG0456	acetyltransferase
C0R09_RS06580	COG1376	ErfK ybiS ycfS ynhG family protein
C0R09_RS06585	COG2807	transmembrane transport
C0R09_RS06600	COG1413	lyase activity
C0R09_RS06610	COG4166	transmembrane transport
C0R09_RS06615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0R09_RS06620	COG2910	NAD(P)H-binding
C0R09_RS06630	COG0534	Mate efflux family protein
C0R09_RS06635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0R09_RS06650	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C0R09_RS06655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C0R09_RS06660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C0R09_RS06665	COG1534	Rna-binding protein
C0R09_RS06670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0R09_RS06675	COG1713	HD superfamily hydrolase involved in NAD metabolism
C0R09_RS06680	COG0799	negative regulation of ribosome biogenesis
C0R09_RS06685	COG2226	methyltransferase
C0R09_RS06695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C0R09_RS06700	COG1555	photosystem II stabilization
C0R09_RS06700	COG1596	polysaccharide export
C0R09_RS06705	COG0367	asparagine synthase
C0R09_RS06710	COG2131	deaminase
C0R09_RS06715	COG0658	competence protein
C0R09_RS06715	COG2333	competence protein COMEC
C0R09_RS06720	COG1595	DNA-templated transcription, initiation
C0R09_RS06735	COG1466	dna polymerase III delta subunit
C0R09_RS06745	COG0268	Binds directly to 16S ribosomal RNA
C0R09_RS06755	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0R09_RS06765	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS06770	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS06775	COG0747	negative chemotaxis
C0R09_RS06780	COG0601	transmembrane transport
C0R09_RS06785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0R09_RS06795	COG0006	proline dipeptidase activity
C0R09_RS06800	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C0R09_RS06805	COG2814	Major facilitator Superfamily
C0R09_RS06810	COG1378	Sugar-specific transcriptional regulator TrmB
C0R09_RS06815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0R09_RS06820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0R09_RS06820	COG1321	iron dependent repressor
C0R09_RS06825	COG1121	(ABC) transporter
C0R09_RS06830	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0R09_RS06840	COG0481	GTPase activity
C0R09_RS06845	COG0582	viral genome integration into host DNA
C0R09_RS06870	COG1396	sequence-specific DNA binding
C0R09_RS06895	COG2002	toxin-antitoxin pair type II binding
C0R09_RS06940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0R09_RS06940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0R09_RS07005	COG0464	growth
C0R09_RS07035	COG4974	Belongs to the 'phage' integrase family
C0R09_RS07165	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0R09_RS07200	COG1475	DNA binding
C0R09_RS07220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0R09_RS07235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0R09_RS07240	COG1420	regulation of RNA biosynthetic process
C0R09_RS07250	COG0443	Heat shock 70 kDa protein
C0R09_RS07260	COG2264	protein methyltransferase activity
C0R09_RS07265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0R09_RS07270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0R09_RS07280	COG1380	Effector of murein hydrolase LrgA
C0R09_RS07285	COG1346	cytolysis
C0R09_RS07290	COG1283	sodium-dependent phosphate transmembrane transporter activity
C0R09_RS07300	COG2801	Transposase and inactivated derivatives
C0R09_RS07310	COG0412	Dienelactone hydrolase
C0R09_RS07315	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0R09_RS07325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0R09_RS07330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0R09_RS07335	COG1610	YqeY-like protein
C0R09_RS07340	COG1030	water channel activity
C0R09_RS07345	COG4864	UPF0365 protein
C0R09_RS07355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C0R09_RS07375	COG1702	phosphate starvation-inducible protein PhoH
C0R09_RS07380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C0R09_RS07385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0R09_RS07390	COG0295	cytidine deaminase activity
C0R09_RS07395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C0R09_RS07405	COG1381	Involved in DNA repair and RecF pathway recombination
C0R09_RS07410	COG0517	IMP dehydrogenase activity
C0R09_RS07415	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C0R09_RS07420	COG0358	DNA primase activity
C0R09_RS07425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0R09_RS07435	COG1960	acyl-CoA dehydrogenase activity
C0R09_RS07440	COG2384	SAM-dependent methyltransferase
C0R09_RS07445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C0R09_RS07460	COG0793	Belongs to the peptidase S41A family
C0R09_RS07520	COG1242	4 iron, 4 sulfur cluster binding
C0R09_RS07530	COG0584	glycerophosphoryl diester phosphodiesterase
C0R09_RS07535	COG0456	acetyltransferase
C0R09_RS07545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0R09_RS07550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0R09_RS07555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0R09_RS07560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0R09_RS07580	COG1309	transcriptional regulator
C0R09_RS07585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0R09_RS07600	COG2249	NAD(P)H dehydrogenase (quinone) activity
C0R09_RS07620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0R09_RS07635	COG0351	phosphomethylpyrimidine kinase
C0R09_RS07650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0R09_RS07655	COG1428	Deoxynucleoside kinase
C0R09_RS07660	COG1428	Deoxynucleoside kinase
C0R09_RS07680	COG1607	acyl-coa hydrolase
C0R09_RS07695	COG2986	histidine ammonia-lyase
C0R09_RS07705	COG4294	response to UV
C0R09_RS07740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0R09_RS07750	COG0535	radical SAM domain protein
C0R09_RS07765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C0R09_RS07770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS07780	COG0367	asparagine synthase
C0R09_RS07785	COG5002	protein histidine kinase activity
C0R09_RS07790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C0R09_RS07800	COG0018	arginyl-trna synthetase
C0R09_RS07815	COG1410	methionine synthase
C0R09_RS07815	COG0646	methionine synthase
C0R09_RS07820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C0R09_RS07820	COG0646	methionine synthase
C0R09_RS07835	COG2116	formate transmembrane transporter activity
C0R09_RS07840	COG0697	spore germination
C0R09_RS07845	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C0R09_RS07855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C0R09_RS07875	COG1122	ATPase activity
C0R09_RS07880	COG1122	ATPase activity
C0R09_RS07905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0R09_RS07935	COG1846	Transcriptional regulator
C0R09_RS07940	COG2814	Major facilitator Superfamily
C0R09_RS07955	COG2814	Major facilitator Superfamily
C0R09_RS07960	COG0640	Transcriptional regulator
C0R09_RS07965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0R09_RS07970	COG1116	anion transmembrane transporter activity
C0R09_RS07975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0R09_RS07980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0R09_RS08000	COG0640	Transcriptional regulator
C0R09_RS08005	COG0798	PFAM Bile acid sodium symporter
C0R09_RS08030	COG1234	tRNA 3'-trailer cleavage
C0R09_RS08040	COG0697	spore germination
C0R09_RS08045	COG0583	DNA-binding transcription factor activity
C0R09_RS08075	COG1671	Belongs to the UPF0178 family
C0R09_RS08080	COG0671	phosphoesterase, PA-phosphatase related
C0R09_RS08110	COG1294	oxidase, subunit
C0R09_RS08115	COG1271	oxidase subunit
C0R09_RS08150	COG0720	synthase
C0R09_RS08165	COG2192	nodulation
C0R09_RS08170	COG4555	ABC transporter
C0R09_RS08200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C0R09_RS08205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0R09_RS08210	COG2226	methyltransferase
C0R09_RS08230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0R09_RS08235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0R09_RS08240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0R09_RS08290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0R09_RS08295	COG4838	Belongs to the UPF0358 family
C0R09_RS08300	COG0387	Pfam Sodium calcium exchanger
C0R09_RS08315	COG1302	Protein conserved in bacteria
C0R09_RS08320	COG0772	Belongs to the SEDS family
C0R09_RS08330	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C0R09_RS08335	COG1525	nuclease
C0R09_RS08360	COG3679	Belongs to the UPF0342 family
C0R09_RS08365	COG4471	UPF0298 protein
C0R09_RS08370	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C0R09_RS08385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C0R09_RS08410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0R09_RS08415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C0R09_RS08420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0R09_RS08425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0R09_RS08430	COG0840	transmembrane signaling receptor activity
C0R09_RS08435	COG0095	Lipoate-protein ligase
C0R09_RS08475	COG2323	membrane
C0R09_RS08485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS08490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS08495	COG2207	Transcriptional regulator
C0R09_RS08495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS08505	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0R09_RS08525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS08525	COG3711	transcriptional antiterminator
C0R09_RS08530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0R09_RS08530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0R09_RS08530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS08540	COG5002	protein histidine kinase activity
C0R09_RS08545	COG0772	Belongs to the SEDS family
C0R09_RS08555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS08575	COG0628	permease
C0R09_RS08580	COG1376	ErfK ybiS ycfS ynhG family protein
C0R09_RS08585	COG2814	Major facilitator Superfamily
C0R09_RS08595	COG2217	Heavy metal translocating P-type atpase
C0R09_RS08600	COG1271	oxidase subunit
C0R09_RS08605	COG1294	oxidase, subunit
C0R09_RS08610	COG4988	ABC transporter
C0R09_RS08615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C0R09_RS08645	COG0745	RESPONSE REGULATOR receiver
C0R09_RS08650	COG2205	protein histidine kinase activity
C0R09_RS08660	COG2390	Transcriptional regulator
C0R09_RS08670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C0R09_RS08680	COG0431	NADPH-dependent FMN reductase
C0R09_RS08685	COG1321	iron dependent repressor
C0R09_RS08690	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0R09_RS08700	COG3872	metal-dependent enzyme
C0R09_RS08710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C0R09_RS08715	COG0006	proline dipeptidase activity
C0R09_RS08720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C0R09_RS08740	COG2707	UPF0756 membrane protein
C0R09_RS08745	COG2045	Belongs to the ComB family
C0R09_RS08750	COG1809	phosphosulfolactate synthase activity
C0R09_RS08765	COG3854	ATPases associated with a variety of cellular activities
C0R09_RS08805	COG0511	ligase activity, forming carbon-carbon bonds
C0R09_RS08810	COG0439	Biotin carboxylase
C0R09_RS08815	COG1302	Protein conserved in bacteria
C0R09_RS08830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0R09_RS08835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C0R09_RS08840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0R09_RS08845	COG1570	exodeoxyribonuclease VII activity
C0R09_RS08850	COG1722	exodeoxyribonuclease VII activity
C0R09_RS08860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C0R09_RS08865	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C0R09_RS08875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0R09_RS08880	COG1438	arginine binding
C0R09_RS08885	COG0497	DNA recombination
C0R09_RS08945	COG5492	domain, Protein
C0R09_RS08945	COG4932	domain protein
C0R09_RS08955	COG2963	transposase activity
C0R09_RS08975	COG0750	zinc metalloprotease
C0R09_RS08980	COG0745	RESPONSE REGULATOR receiver
C0R09_RS08990	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0R09_RS08990	COG2124	cytochrome p450
C0R09_RS08995	COG3191	aminopeptidase activity
C0R09_RS09010	COG1285	pathogenesis
C0R09_RS09015	COG0180	Tryptophanyl-tRNA synthetase
C0R09_RS09030	COG1316	TRANSCRIPTIONal
C0R09_RS09035	COG0745	RESPONSE REGULATOR receiver
C0R09_RS09050	COG2755	lipolytic protein G-D-S-L family
C0R09_RS09050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0R09_RS09055	COG1566	PFAM secretion protein HlyD family protein
C0R09_RS09060	COG1136	(ABC) transporter
C0R09_RS09065	COG0577	efflux transmembrane transporter activity
C0R09_RS09075	COG1595	DNA-templated transcription, initiation
C0R09_RS09115	COG3829	transcription factor binding
C0R09_RS09115	COG3290	protein histidine kinase activity
C0R09_RS09125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0R09_RS09130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0R09_RS09135	COG0022	dehydrogenase e1 component
C0R09_RS09140	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0R09_RS09150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C0R09_RS09150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C0R09_RS09155	COG0346	lactoylglutathione lyase activity
C0R09_RS09160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0R09_RS09165	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0R09_RS09180	COG0494	nUDIX hydrolase
C0R09_RS09185	COG1379	DNA repair
C0R09_RS09190	COG1300	Membrane
C0R09_RS09195	COG0735	belongs to the Fur family
C0R09_RS09205	COG4974	Belongs to the 'phage' integrase family
C0R09_RS09210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C0R09_RS09230	COG3842	ATPase activity
C0R09_RS09235	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0R09_RS09240	COG1177	transmembrane transport
C0R09_RS09245	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0R09_RS09255	COG0601	transmembrane transport
C0R09_RS09260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0R09_RS09265	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS09270	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS09275	COG0840	transmembrane signaling receptor activity
C0R09_RS09280	COG1686	Belongs to the peptidase S11 family
C0R09_RS09290	COG2172	sigma factor antagonist activity
C0R09_RS09315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0R09_RS09330	COG0697	spore germination
C0R09_RS09335	COG0019	diaminopimelate decarboxylase activity
C0R09_RS09340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0R09_RS09355	COG1396	sequence-specific DNA binding
C0R09_RS09465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0R09_RS09470	COG1846	Transcriptional regulator
C0R09_RS09485	COG1114	Component of the transport system for branched-chain amino acids
C0R09_RS09515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0R09_RS09520	COG1994	Peptidase M50
C0R09_RS09525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C0R09_RS09530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0R09_RS09535	COG1686	Belongs to the peptidase S11 family
C0R09_RS09540	COG2715	membrane protein required for spore maturation
C0R09_RS09545	COG0700	Nucleoside recognition
C0R09_RS09550	COG1187	pseudouridine synthase activity
C0R09_RS09555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0R09_RS09560	COG1333	cytochrome c biogenesis protein
C0R09_RS09565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0R09_RS09570	COG0745	RESPONSE REGULATOR receiver
C0R09_RS09575	COG5002	protein histidine kinase activity
C0R09_RS09585	COG2814	Major facilitator Superfamily
C0R09_RS09600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0R09_RS09610	COG1141	Ferredoxin
C0R09_RS09625	COG0514	ATP-dependent DNA helicase (RecQ)
C0R09_RS09630	COG1266	CAAX protease self-immunity
C0R09_RS09640	COG0492	ferredoxin-NADP+ reductase activity
C0R09_RS09645	COG4862	establishment of competence for transformation
C0R09_RS09650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0R09_RS09655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0R09_RS09665	COG2339	peptidase activity
C0R09_RS09675	COG2959	enzyme of heme biosynthesis
C0R09_RS09690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C0R09_RS09700	COG0539	negative regulation of cytoplasmic translation
C0R09_RS09720	COG1160	GTP binding
C0R09_RS09725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C0R09_RS09730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C0R09_RS09765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C0R09_RS09775	COG0302	gtp cyclohydrolase
C0R09_RS09805	COG0741	lytic transglycosylase activity
C0R09_RS09820	COG3414	Phosphotransferase system galactitol-specific IIB component
C0R09_RS09825	COG3775	system Galactitol-specific IIC component
C0R09_RS09830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS09830	COG3711	transcriptional antiterminator
C0R09_RS09835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0R09_RS09840	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0R09_RS09840	COG0022	dehydrogenase e1 component
C0R09_RS09845	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0R09_RS09850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0R09_RS09855	COG2390	Transcriptional regulator
C0R09_RS09870	COG0142	geranyltranstransferase activity
C0R09_RS09885	COG0163	prenyltransferase activity
C0R09_RS09900	COG0105	UTP biosynthetic process
C0R09_RS09905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0R09_RS09910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C0R09_RS09915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C0R09_RS09930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C0R09_RS09935	COG0134	indole-3-glycerol-phosphate synthase activity
C0R09_RS09940	COG0135	phosphoribosylanthranilate isomerase activity
C0R09_RS09945	COG0133	tryptophan synthase activity
C0R09_RS09950	COG0159	tryptophan synthase activity
C0R09_RS09955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0R09_RS09960	COG0287	Prephenate dehydrogenase
C0R09_RS09965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C0R09_RS10020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0R09_RS10040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0R09_RS10045	COG1694	Mazg nucleotide pyrophosphohydrolase
C0R09_RS10050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C0R09_RS10055	COG1803	Methylglyoxal synthase
C0R09_RS10060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0R09_RS10065	COG0438	transferase activity, transferring glycosyl groups
C0R09_RS10070	COG0617	tRNA 3'-terminal CCA addition
C0R09_RS10075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C0R09_RS10075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C0R09_RS10080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C0R09_RS10085	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C0R09_RS10090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C0R09_RS10100	COG1199	ATP-dependent helicase activity
C0R09_RS10100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0R09_RS10110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C0R09_RS10115	COG0402	S-adenosylhomocysteine deaminase activity
C0R09_RS10130	COG5353	protein conserved in bacteria
C0R09_RS10140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0R09_RS10155	COG0436	Aminotransferase
C0R09_RS10160	COG0017	Asparaginyl-tRNA synthetase
C0R09_RS10165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS10170	COG4605	iron ion homeostasis
C0R09_RS10175	COG4604	ABC transporter, ATP-binding protein
C0R09_RS10180	COG4607	ABC-type enterochelin transport system periplasmic component
C0R09_RS10185	COG3935	DnaD domain protein
C0R09_RS10195	COG0438	transferase activity, transferring glycosyl groups
C0R09_RS10205	COG1215	transferase activity, transferring glycosyl groups
C0R09_RS10210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0R09_RS10220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C0R09_RS10225	COG1164	Oligoendopeptidase f
C0R09_RS10230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0R09_RS10235	COG0363	glucosamine-6-phosphate deaminase activity
C0R09_RS10240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0R09_RS10255	COG0604	alcohol dehydrogenase
C0R09_RS10265	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS10270	COG1959	2 iron, 2 sulfur cluster binding
C0R09_RS10275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0R09_RS10290	COG0066	3-isopropylmalate dehydratase activity
C0R09_RS10295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C0R09_RS10300	COG0583	DNA-binding transcription factor activity
C0R09_RS10305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0R09_RS10310	COG0584	glycerophosphoryl diester phosphodiesterase
C0R09_RS10315	COG0564	pseudouridine synthase activity
C0R09_RS10325	COG0697	spore germination
C0R09_RS10330	COG3069	C4-dicarboxylate transmembrane transporter activity
C0R09_RS10390	COG0659	secondary active sulfate transmembrane transporter activity
C0R09_RS10435	COG1301	dicarboxylic acid transport
C0R09_RS10465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C0R09_RS10470	COG3290	protein histidine kinase activity
C0R09_RS10485	COG0778	Nitroreductase
C0R09_RS10500	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS10505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0R09_RS10510	COG0367	asparagine synthase
C0R09_RS10515	COG2070	2-Nitropropane dioxygenase
C0R09_RS10515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C0R09_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS10520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS10520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0R09_RS10520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0R09_RS10520	COG3321	synthase
C0R09_RS10525	COG4221	oxidoreductase activity
C0R09_RS10525	COG3321	synthase
C0R09_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS10525	COG3321	synthase
C0R09_RS10525	COG4221	oxidoreductase activity
C0R09_RS10525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS10525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS10530	COG0300	oxidoreductase activity
C0R09_RS10530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS10530	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS10530	COG3321	synthase
C0R09_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS10535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS10535	COG4221	oxidoreductase activity
C0R09_RS10535	COG3321	synthase
C0R09_RS10545	COG2986	histidine ammonia-lyase
C0R09_RS10550	COG0346	lactoylglutathione lyase activity
C0R09_RS10565	COG3732	PTS system glucitol sorbitol-specific
C0R09_RS10585	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0R09_RS10605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS10610	COG1690	Belongs to the RtcB family
C0R09_RS10615	COG0778	Nitroreductase
C0R09_RS10620	COG2249	NAD(P)H dehydrogenase (quinone) activity
C0R09_RS10625	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0R09_RS10650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS10655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS10665	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0R09_RS10705	COG3583	domain protein
C0R09_RS10705	COG3584	3D domain protein
C0R09_RS10835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0R09_RS10885	COG1819	glycosyl
C0R09_RS10890	COG2226	methyltransferase
C0R09_RS10895	COG2188	Transcriptional regulator
C0R09_RS10900	COG2723	6-phospho-beta-galactosidase activity
C0R09_RS10925	COG0786	glutamate:sodium symporter activity
C0R09_RS10940	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
C0R09_RS10955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS10965	COG3541	Predicted nucleotidyltransferase
C0R09_RS10970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0R09_RS10990	COG4112	unkown
C0R09_RS11000	COG0641	radical SAM
C0R09_RS11015	COG2364	Membrane
C0R09_RS11025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0R09_RS11035	COG2723	6-phospho-beta-galactosidase activity
C0R09_RS11040	COG2723	6-phospho-beta-galactosidase activity
C0R09_RS11045	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C0R09_RS11055	COG0714	Associated with various cellular activities
C0R09_RS11090	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C0R09_RS11095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0R09_RS11100	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C0R09_RS11105	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C0R09_RS11120	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C0R09_RS11125	COG2357	RelA SpoT domain protein
C0R09_RS11130	COG1027	Aspartate ammonia-lyase
C0R09_RS11135	COG1686	Belongs to the peptidase S11 family
C0R09_RS11145	COG0622	Phosphoesterase
C0R09_RS11150	COG0640	Transcriptional regulator
C0R09_RS11155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0R09_RS11160	COG1902	pentaerythritol trinitrate reductase activity
C0R09_RS11170	COG0697	spore germination
C0R09_RS11175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C0R09_RS11180	COG2169	Transcriptional regulator
C0R09_RS11185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0R09_RS11210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0R09_RS11225	COG1956	GAF domain-containing protein
C0R09_RS11240	COG2197	response regulator
C0R09_RS11275	COG3173	Aminoglycoside phosphotransferase
C0R09_RS11280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C0R09_RS11285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0R09_RS11290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0R09_RS11295	COG1335	isochorismatase
C0R09_RS11300	COG1051	belongs to the nudix hydrolase family
C0R09_RS11305	COG0346	lactoylglutathione lyase activity
C0R09_RS11310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0R09_RS11310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0R09_RS11320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0R09_RS11320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0R09_RS11325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C0R09_RS11335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0R09_RS11345	COG1396	sequence-specific DNA binding
C0R09_RS11360	COG1917	Cupin 2, conserved barrel domain protein
C0R09_RS11360	COG4977	sequence-specific DNA binding
C0R09_RS11370	COG2376	Dihydroxyacetone kinase
C0R09_RS11405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0R09_RS11410	COG2271	Major facilitator Superfamily
C0R09_RS11415	COG3257	ureidoglycine aminohydrolase activity
C0R09_RS11420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C0R09_RS11425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C0R09_RS11430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0R09_RS11435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0R09_RS11450	COG0584	glycerophosphoryl diester phosphodiesterase
C0R09_RS11455	COG0251	oxidation-reduction process
C0R09_RS11520	COG3209	COG3209 Rhs family protein
C0R09_RS11550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C0R09_RS11555	COG0590	tRNA wobble adenosine to inosine editing
C0R09_RS11570	COG0745	RESPONSE REGULATOR receiver
C0R09_RS11580	COG0666	response to abiotic stimulus
C0R09_RS11590	COG2963	transposase activity
C0R09_RS11600	COG0697	spore germination
C0R09_RS11605	COG1802	Transcriptional regulator
C0R09_RS11610	COG2267	carboxylic ester hydrolase activity
C0R09_RS11645	COG1316	TRANSCRIPTIONal
C0R09_RS11655	COG4319	ketosteroid isomerase
C0R09_RS11665	COG1595	DNA-templated transcription, initiation
C0R09_RS11715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0R09_RS11755	COG2814	Major facilitator Superfamily
C0R09_RS11765	COG2132	Multicopper oxidase
C0R09_RS11785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C0R09_RS11790	COG1378	Sugar-specific transcriptional regulator TrmB
C0R09_RS11805	COG1657	PFAM Prenyltransferase squalene oxidase
C0R09_RS11815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0R09_RS11830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS11870	COG1376	ErfK ybiS ycfS ynhG family protein
C0R09_RS11875	COG2267	carboxylic ester hydrolase activity
C0R09_RS11900	COG0189	ligase activity
C0R09_RS11905	COG0477	Major facilitator Superfamily
C0R09_RS11915	COG0723	plastoquinol--plastocyanin reductase activity
C0R09_RS11915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0R09_RS11940	COG3655	Transcriptional regulator
C0R09_RS11945	COG1114	Component of the transport system for branched-chain amino acids
C0R09_RS11950	COG1132	(ABC) transporter
C0R09_RS11955	COG1132	(ABC) transporter
C0R09_RS11975	COG2130	NADP-dependent
C0R09_RS11980	COG1309	transcriptional regulator
C0R09_RS11985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0R09_RS11985	COG2124	cytochrome p450
C0R09_RS11995	COG0640	Transcriptional regulator
C0R09_RS12000	COG3832	glyoxalase III activity
C0R09_RS12025	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS12065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS12070	COG1132	(ABC) transporter
C0R09_RS12075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0R09_RS12090	COG3546	catalase activity
C0R09_RS12095	COG4166	transmembrane transport
C0R09_RS12100	COG0601	transmembrane transport
C0R09_RS12105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0R09_RS12110	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS12115	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS12175	COG1959	2 iron, 2 sulfur cluster binding
C0R09_RS12180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0R09_RS12190	COG1196	nuclear chromosome segregation
C0R09_RS12190	COG0741	lytic transglycosylase activity
C0R09_RS12190	COG0739	heme binding
C0R09_RS12210	COG0697	spore germination
C0R09_RS12230	COG0385	Bile acid
C0R09_RS12235	COG1802	Transcriptional regulator
C0R09_RS12240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0R09_RS12245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0R09_RS12250	COG1780	Probably involved in ribonucleotide reductase function
C0R09_RS12255	COG4974	Belongs to the 'phage' integrase family
C0R09_RS12260	COG0488	(ABC) transporter
C0R09_RS12265	COG2217	Heavy metal translocating P-type atpase
C0R09_RS12290	COG2814	Major facilitator Superfamily
C0R09_RS12295	COG1304	FMN binding
C0R09_RS12350	COG5002	protein histidine kinase activity
C0R09_RS12355	COG0745	RESPONSE REGULATOR receiver
C0R09_RS12360	COG2132	Multicopper oxidase
C0R09_RS12365	COG0531	amino acid
C0R09_RS12400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS12435	COG2814	Major facilitator Superfamily
C0R09_RS12470	COG1473	amidohydrolase
C0R09_RS12480	COG3192	ethanolamine utilization protein
C0R09_RS12485	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C0R09_RS12495	COG4869	propanediol catabolic process
C0R09_RS12505	COG1454	alcohol dehydrogenase
C0R09_RS12505	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS12510	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C0R09_RS12515	COG4816	utilization protein
C0R09_RS12525	COG4303	Ethanolamine ammonia lyase large subunit
C0R09_RS12555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0R09_RS12560	COG2363	Small membrane protein
C0R09_RS12565	COG0697	spore germination
C0R09_RS12575	COG2207	Transcriptional regulator
C0R09_RS12605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0R09_RS12610	COG0604	alcohol dehydrogenase
C0R09_RS12620	COG2427	Protein of unknown function (DUF1641)
C0R09_RS12625	COG3383	formate dehydrogenase (NAD+) activity
C0R09_RS12635	COG2814	Major facilitator Superfamily
C0R09_RS12650	COG1132	(ABC) transporter
C0R09_RS12655	COG1132	(ABC) transporter
C0R09_RS12670	COG2318	DinB family
C0R09_RS12675	COG3359	exonuclease
C0R09_RS12680	COG1205	dead DEAH box helicase
C0R09_RS12680	COG1111	helicase
C0R09_RS12685	COG1959	2 iron, 2 sulfur cluster binding
C0R09_RS12690	COG0306	phosphate transporter
C0R09_RS12695	COG1392	Phosphate transport regulator
C0R09_RS12700	COG1309	transcriptional regulator
C0R09_RS12710	COG1233	COG1233 Phytoene dehydrogenase and related
C0R09_RS12725	COG0242	peptide deformylase activity
C0R09_RS12735	COG0840	transmembrane signaling receptor activity
C0R09_RS12745	COG1114	Component of the transport system for branched-chain amino acids
C0R09_RS12775	COG2329	Antibiotic biosynthesis monooxygenase
C0R09_RS12785	COG1253	flavin adenine dinucleotide binding
C0R09_RS12790	COG0789	Transcriptional regulator
C0R09_RS12795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0R09_RS12800	COG0531	amino acid
C0R09_RS12805	COG0583	DNA-binding transcription factor activity
C0R09_RS12815	COG1876	peptidase activity
C0R09_RS12820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0R09_RS12825	COG0537	adenosine 5'-monophosphoramidase activity
C0R09_RS12845	COG1349	DNA-binding transcription factor activity
C0R09_RS12850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0R09_RS12875	COG1120	ATPase activity
C0R09_RS12880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS12885	COG2323	membrane
C0R09_RS12895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0R09_RS12915	COG1131	(ABC) transporter
C0R09_RS12925	COG1595	DNA-templated transcription, initiation
C0R09_RS12935	COG0662	Cupin 2, conserved barrel domain protein
C0R09_RS12980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0R09_RS12985	COG1737	Transcriptional regulator
C0R09_RS12990	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C0R09_RS12995	COG1263	PTS System
C0R09_RS12995	COG2190	(PTS) system
C0R09_RS12995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0R09_RS13000	COG3684	Belongs to the aldolase LacD family
C0R09_RS13015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0R09_RS13020	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS13045	COG0697	spore germination
C0R09_RS13090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0R09_RS13095	COG4221	oxidoreductase activity
C0R09_RS13095	COG3321	synthase
C0R09_RS13095	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS13095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS13125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0R09_RS13130	COG2030	dehydratase
C0R09_RS13135	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS13145	COG0512	Glutamine amidotransferase of anthranilate synthase
C0R09_RS13145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0R09_RS13150	COG0512	Glutamine amidotransferase of anthranilate synthase
C0R09_RS13150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0R09_RS13155	COG2318	DinB family
C0R09_RS13160	COG1396	sequence-specific DNA binding
C0R09_RS13165	COG0006	proline dipeptidase activity
C0R09_RS13170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0R09_RS13175	COG0045	succinate-CoA ligase (ADP-forming) activity
C0R09_RS13180	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0R09_RS13185	COG0567	Dehydrogenase, E1 component
C0R09_RS13190	COG0471	metal ion transport
C0R09_RS13200	COG3192	ethanolamine utilization protein
C0R09_RS13210	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C0R09_RS13220	COG4869	propanediol catabolic process
C0R09_RS13235	COG1454	alcohol dehydrogenase
C0R09_RS13235	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS13245	COG4816	utilization protein
C0R09_RS13255	COG4303	Ethanolamine ammonia lyase large subunit
C0R09_RS13260	COG4819	ethanolamine utilization protein
C0R09_RS13300	COG0644	oxidoreductase
C0R09_RS13300	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C0R09_RS13305	COG1119	ATPase activity
C0R09_RS13310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0R09_RS13365	COG3964	amidohydrolase
C0R09_RS13370	COG3711	transcriptional antiterminator
C0R09_RS13380	COG3973	AAA domain
C0R09_RS13405	COG0243	molybdopterin cofactor binding
C0R09_RS13415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0R09_RS13420	COG2223	nitrite transmembrane transporter activity
C0R09_RS13425	COG0535	radical SAM domain protein
C0R09_RS13435	COG0535	radical SAM domain protein
C0R09_RS13440	COG0477	Major facilitator Superfamily
C0R09_RS13445	COG3858	chitin binding
C0R09_RS13445	COG1388	LysM domain
C0R09_RS13460	COG0745	RESPONSE REGULATOR receiver
C0R09_RS13465	COG5002	protein histidine kinase activity
C0R09_RS13475	COG0706	membrane insertase activity
C0R09_RS13485	COG2861	carbohydrate metabolic process
C0R09_RS13490	COG1472	Belongs to the glycosyl hydrolase 3 family
C0R09_RS13495	COG3876	Protein conserved in bacteria
C0R09_RS13500	COG2814	Major facilitator Superfamily
C0R09_RS13505	COG0492	ferredoxin-NADP+ reductase activity
C0R09_RS13520	COG0346	lactoylglutathione lyase activity
C0R09_RS13540	COG0813	purine-nucleoside phosphorylase activity
C0R09_RS13545	COG1619	proteins homologs of microcin C7 resistance protein MccF
C0R09_RS13550	COG5002	protein histidine kinase activity
C0R09_RS13575	COG1744	ABC transporter substrate-binding protein PnrA-like
C0R09_RS13580	COG3852	Histidine kinase
C0R09_RS13585	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0R09_RS13590	COG1335	isochorismatase
C0R09_RS13610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C0R09_RS13615	COG1368	sulfuric ester hydrolase activity
C0R09_RS13620	COG2385	sporulation resulting in formation of a cellular spore
C0R09_RS13630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0R09_RS13640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0R09_RS13645	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS13655	COG0791	NLP P60 protein
C0R09_RS13660	COG4948	Mandelate Racemase Muconate Lactonizing
C0R09_RS13665	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0R09_RS13670	COG1129	ABC transporter
C0R09_RS13685	COG1122	ATPase activity
C0R09_RS13690	COG4120	Belongs to the binding-protein-dependent transport system permease family
C0R09_RS13700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0R09_RS13720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0R09_RS13725	COG0531	amino acid
C0R09_RS13735	COG0482	sulfurtransferase activity
C0R09_RS13755	COG0519	Catalyzes the synthesis of GMP from XMP
C0R09_RS13760	COG0251	oxidation-reduction process
C0R09_RS13765	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0R09_RS13770	COG1011	Hydrolase
C0R09_RS13775	COG3681	Belongs to the UPF0597 family
C0R09_RS13785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS13790	COG2169	Transcriptional regulator
C0R09_RS13800	COG1132	(ABC) transporter
C0R09_RS13805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS13810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS13820	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS13835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0R09_RS13840	COG0488	(ABC) transporter
C0R09_RS13845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0R09_RS13850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0R09_RS13890	COG3093	addiction module antidote protein HigA
C0R09_RS13900	COG0673	inositol 2-dehydrogenase activity
C0R09_RS13905	COG0463	Glycosyl transferase, family 2
C0R09_RS13905	COG0457	Tetratricopeptide repeat
C0R09_RS13910	COG5337	Spore coat protein CotH
C0R09_RS13915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0R09_RS13920	COG0785	Cytochrome C biogenesis protein
C0R09_RS13925	COG3186	Phenylalanine-4-hydroxylase
C0R09_RS13945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C0R09_RS13950	COG0352	thiamine-phosphate diphosphorylase activity
C0R09_RS13955	COG2022	thiamine diphosphate biosynthetic process
C0R09_RS13965	COG0352	thiamine-phosphate diphosphorylase activity
C0R09_RS13980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C0R09_RS13985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C0R09_RS13990	COG0095	Lipoate-protein ligase
C0R09_RS13995	COG0583	DNA-binding transcription factor activity
C0R09_RS14040	COG2056	Na+-H+ antiporter family
C0R09_RS14045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0R09_RS14055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0R09_RS14065	COG1755	Isoprenylcysteine carboxyl methyltransferase
C0R09_RS14070	COG3424	synthase
C0R09_RS14075	COG1114	Component of the transport system for branched-chain amino acids
C0R09_RS14080	COG0464	growth
C0R09_RS14095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C0R09_RS14100	COG0187	DNA topoisomerase II activity
C0R09_RS14105	COG0217	transcriptional regulatory protein
C0R09_RS14130	COG1131	(ABC) transporter
C0R09_RS14145	COG1595	DNA-templated transcription, initiation
C0R09_RS14150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C0R09_RS14155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C0R09_RS14160	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS14165	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS14170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0R09_RS14175	COG0601	transmembrane transport
C0R09_RS14180	COG0747	negative chemotaxis
C0R09_RS14185	COG0778	Nitroreductase
C0R09_RS14190	COG2259	Doxx family
C0R09_RS14195	COG1846	Transcriptional regulator
C0R09_RS14200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS14205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS14215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS14225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS14260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS14295	COG1396	sequence-specific DNA binding
C0R09_RS14300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0R09_RS14315	COG2707	UPF0756 membrane protein
C0R09_RS14325	COG4848	Belongs to the UPF0354 family
C0R09_RS14345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0R09_RS14365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C0R09_RS14380	COG0022	dehydrogenase e1 component
C0R09_RS14410	COG0316	Belongs to the HesB IscA family
C0R09_RS14420	COG3973	AAA domain
C0R09_RS14490	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0R09_RS14570	COG4224	UPF0291 protein
C0R09_RS14580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0R09_RS14585	COG2839	Protein conserved in bacteria
C0R09_RS14600	COG0697	spore germination
C0R09_RS14625	COG0697	spore germination
C0R09_RS14630	COG1396	sequence-specific DNA binding
C0R09_RS14630	COG3800	Transcriptional regulator
C0R09_RS14695	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0R09_RS14700	COG5002	protein histidine kinase activity
C0R09_RS14705	COG0745	RESPONSE REGULATOR receiver
C0R09_RS14715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0R09_RS14765	COG0456	acetyltransferase
C0R09_RS14800	COG1408	metallophosphoesterase
C0R09_RS14840	COG0745	RESPONSE REGULATOR receiver
C0R09_RS14850	COG1120	ATPase activity
C0R09_RS14855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS14910	COG0738	Major facilitator superfamily
C0R09_RS14915	COG0110	maltose O-acetyltransferase activity
C0R09_RS14920	COG1940	carbohydrate kinase activity
C0R09_RS14950	COG0747	negative chemotaxis
C0R09_RS14960	COG0488	(ABC) transporter
C0R09_RS14970	COG0640	Transcriptional regulator
C0R09_RS15020	COG2318	DinB family
C0R09_RS15045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0R09_RS15065	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0R09_RS15075	COG0346	lactoylglutathione lyase activity
C0R09_RS15085	COG1388	LysM domain
C0R09_RS15095	COG1132	(ABC) transporter
C0R09_RS15100	COG1132	(ABC) transporter
C0R09_RS15125	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0R09_RS15180	COG0582	viral genome integration into host DNA
C0R09_RS15185	COG0174	glutamine synthetase
C0R09_RS15190	COG0789	Transcriptional regulator
C0R09_RS15195	COG0768	penicillin binding
C0R09_RS15200	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C0R09_RS15205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0R09_RS15210	COG0464	growth
C0R09_RS15220	COG1595	DNA-templated transcription, initiation
C0R09_RS15225	COG2207	Transcriptional regulator
C0R09_RS15225	COG1917	Cupin 2, conserved barrel domain protein
C0R09_RS15245	COG1349	DNA-binding transcription factor activity
C0R09_RS15250	COG1923	regulation of RNA biosynthetic process
C0R09_RS15255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C0R09_RS15260	COG2136	Putative SAM-dependent methyltransferase
C0R09_RS15260	COG2521	methyltransferase
C0R09_RS15340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C0R09_RS15345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C0R09_RS15360	COG4550	Control of competence regulator ComK, YlbF/YmcA
C0R09_RS15365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0R09_RS15375	COG3620	sequence-specific DNA binding
C0R09_RS15400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C0R09_RS15410	COG2076	Multidrug Resistance protein
C0R09_RS15415	COG2076	Multidrug Resistance protein
C0R09_RS15420	COG1486	melibiose metabolic process
C0R09_RS15425	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0R09_RS15430	COG3394	polysaccharide catabolic process
C0R09_RS15445	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C0R09_RS15445	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C0R09_RS15450	COG2814	Major facilitator Superfamily
C0R09_RS15460	COG1361	Conserved repeat domain
C0R09_RS15470	COG0095	Lipoate-protein ligase
C0R09_RS15475	COG0517	IMP dehydrogenase activity
C0R09_RS15485	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C0R09_RS15490	COG1234	tRNA 3'-trailer cleavage
C0R09_RS15495	COG3949	Membrane
C0R09_RS15500	COG1013	pyruvate-flavodoxin oxidoreductase activity
C0R09_RS15505	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C0R09_RS15505	COG0674	pyruvate-flavodoxin oxidoreductase activity
C0R09_RS15510	COG2359	stage V sporulation protein S
C0R09_RS15515	COG1692	metallophosphoesterase
C0R09_RS15530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C0R09_RS15535	COG0513	Belongs to the DEAD box helicase family
C0R09_RS15545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0R09_RS15550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0R09_RS15555	COG1426	Protein conserved in bacteria
C0R09_RS15570	COG0300	oxidoreductase activity
C0R09_RS15575	COG0612	Peptidase, M16
C0R09_RS15580	COG0612	Peptidase, M16
C0R09_RS15590	COG1079	Belongs to the binding-protein-dependent transport system permease family
C0R09_RS15595	COG4603	Belongs to the binding-protein-dependent transport system permease family
C0R09_RS15600	COG3845	ABC transporter
C0R09_RS15605	COG1744	ABC transporter substrate-binding protein PnrA-like
C0R09_RS15610	COG1674	ftsk spoiiie
C0R09_RS15620	COG0740	serine-type endopeptidase activity
C0R09_RS15635	COG1819	glycosyl
C0R09_RS15650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C0R09_RS15655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0R09_RS15660	COG0527	aspartate kinase activity
C0R09_RS15665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0R09_RS15670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0R09_RS15675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0R09_RS15680	COG1873	PFAM PRC-barrel domain
C0R09_RS15690	COG0612	Peptidase, M16
C0R09_RS15695	COG0726	polysaccharide deacetylase
C0R09_RS15700	COG1185	polyribonucleotide nucleotidyltransferase activity
C0R09_RS15705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C0R09_RS15710	COG0196	riboflavin kinase activity
C0R09_RS15715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C0R09_RS15720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0R09_RS15725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C0R09_RS15730	COG1550	Protein conserved in bacteria
C0R09_RS15735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C0R09_RS15745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C0R09_RS15750	COG0195	Participates in both transcription termination and antitermination
C0R09_RS15755	COG0779	Required for maturation of 30S ribosomal subunits
C0R09_RS15765	COG2176	DNA-directed DNA polymerase activity
C0R09_RS15770	COG0442	prolyl-tRNA aminoacylation
C0R09_RS15775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C0R09_RS15780	COG0750	zinc metalloprotease
C0R09_RS15785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C0R09_RS15790	COG4589	Belongs to the CDS family
C0R09_RS15795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C0R09_RS15800	COG0233	cytoplasmic translational termination
C0R09_RS15805	COG0528	UMP kinase activity
C0R09_RS15810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C0R09_RS15815	COG0052	Belongs to the universal ribosomal protein uS2 family
C0R09_RS15840	COG1191	sigma factor activity
C0R09_RS15850	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C0R09_RS15855	COG1776	CheC inhibitor of MCP methylation
C0R09_RS15860	COG0835	chemotaxis
C0R09_RS15865	COG2198	Histidine kinase
C0R09_RS15865	COG0643	Histidine kinase
C0R09_RS15870	COG2201	protein-glutamate methylesterase activity
C0R09_RS15875	COG0455	bacterial-type flagellum organization
C0R09_RS15880	COG1419	protein localization to endoplasmic reticulum
C0R09_RS15885	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0R09_RS15890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0R09_RS15895	COG1684	flagellar biosynthetic protein fliR
C0R09_RS15900	COG1987	bacterial-type flagellum assembly
C0R09_RS15905	COG1338	Plays a role in the flagellum-specific transport system
C0R09_RS15910	COG3190	flagellar
C0R09_RS15915	COG2201	protein-glutamate methylesterase activity
C0R09_RS15920	COG1776	CheC inhibitor of MCP methylation
C0R09_RS15920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0R09_RS15925	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0R09_RS15930	COG1580	Controls the rotational direction of flagella during chemotaxis
C0R09_RS15935	COG1582	Flagellar protein (FlbD)
C0R09_RS15940	COG4786	Flagellar basal body rod
C0R09_RS15965	COG1157	protein secretion by the type III secretion system
C0R09_RS15975	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0R09_RS15980	COG1766	The M ring may be actively involved in energy transduction
C0R09_RS15985	COG1677	Flagellar hook-basal body complex protein FliE
C0R09_RS15990	COG1558	bacterial-type flagellum-dependent cell motility
C0R09_RS15995	COG1815	bacterial-type flagellum-dependent cell motility
C0R09_RS16000	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0R09_RS16005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C0R09_RS16010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C0R09_RS16015	COG4974	Belongs to the 'phage' integrase family
C0R09_RS16020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C0R09_RS16025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0R09_RS16030	COG0758	DNA mediated transformation
C0R09_RS16035	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0R09_RS16040	COG0045	succinate-CoA ligase (ADP-forming) activity
C0R09_RS16065	COG0488	(ABC) transporter
C0R09_RS16075	COG2002	toxin-antitoxin pair type II binding
C0R09_RS16080	COG0792	nuclease activity
C0R09_RS16085	COG2257	FlhB HrpN YscU SpaS Family
C0R09_RS16095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C0R09_RS16110	COG0335	large ribosomal subunit rRNA binding
C0R09_RS16115	COG0336	Belongs to the RNA methyltransferase TrmD family
C0R09_RS16120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C0R09_RS16130	COG1837	Belongs to the UPF0109 family
C0R09_RS16135	COG0228	four-way junction DNA binding
C0R09_RS16140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0R09_RS16145	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C0R09_RS16150	COG0552	protein localization to endoplasmic reticulum
C0R09_RS16155	COG1196	nuclear chromosome segregation
C0R09_RS16160	COG0571	ribonuclease III activity
C0R09_RS16165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0R09_RS16170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0R09_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS16180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C0R09_RS16190	COG0416	fatty acid biosynthetic process
C0R09_RS16195	COG1349	DNA-binding transcription factor activity
C0R09_RS16200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C0R09_RS16210	COG1323	Belongs to the UPF0348 family
C0R09_RS16215	COG3480	Lon protease (S16) C-terminal proteolytic domain
C0R09_RS16220	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0R09_RS16225	COG3314	Sporulation integral membrane protein YlbJ
C0R09_RS16230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C0R09_RS16235	COG0742	ribosomal rna small subunit methyltransferase
C0R09_RS16240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C0R09_RS16245	COG0386	Belongs to the glutathione peroxidase family
C0R09_RS16250	COG0789	Transcriptional regulator
C0R09_RS16265	COG3285	dna ligase
C0R09_RS16265	COG1793	dna ligase
C0R09_RS16280	COG0306	phosphate transporter
C0R09_RS16295	COG0346	lactoylglutathione lyase activity
C0R09_RS16300	COG1846	Transcriptional regulator
C0R09_RS16345	COG2357	RelA SpoT domain protein
C0R09_RS16370	COG1846	Transcriptional regulator
C0R09_RS16385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0R09_RS16395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0R09_RS16400	COG1760	l-serine dehydratase
C0R09_RS16405	COG1760	l-serine dehydratase
C0R09_RS16420	COG0697	spore germination
C0R09_RS16430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0R09_RS16430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C0R09_RS16445	COG1307	EDD domain protein, DegV family
C0R09_RS16450	COG1461	Dihydroxyacetone kinase
C0R09_RS16455	COG1302	Protein conserved in bacteria
C0R09_RS16460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0R09_RS16470	COG1564	THIamine pyrophosphokinase
C0R09_RS16475	COG1126	abc transporter atp-binding protein
C0R09_RS16480	COG0765	amino acid transport
C0R09_RS16485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0R09_RS16490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C0R09_RS16495	COG1162	GTPase activity
C0R09_RS16500	COG2815	serine threonine protein kinase
C0R09_RS16500	COG0515	serine threonine protein kinase
C0R09_RS16505	COG0631	protein serine/threonine phosphatase activity
C0R09_RS16510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C0R09_RS16515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0R09_RS16515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0R09_RS16520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C0R09_RS16525	COG0242	peptide deformylase activity
C0R09_RS16530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0R09_RS16535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0R09_RS16550	COG1758	RNA polymerase activity
C0R09_RS16555	COG0194	GDP metabolic process
C0R09_RS16560	COG2052	Domain of unknown function (DUF370)
C0R09_RS16565	COG1561	YicC-like family, N-terminal region
C0R09_RS16595	COG1547	Domain of unknown function (DUF309)
C0R09_RS16610	COG4846	Membrane protein involved in cytochrome C biogenesis
C0R09_RS16615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0R09_RS16620	COG2076	Multidrug Resistance protein
C0R09_RS16640	COG0284	orotidine-5'-phosphate decarboxylase activity
C0R09_RS16645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0R09_RS16650	COG0505	Belongs to the CarA family
C0R09_RS16655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0R09_RS16660	COG0540	Belongs to the ATCase OTCase family
C0R09_RS16670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C0R09_RS16675	COG0564	pseudouridine synthase activity
C0R09_RS16680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C0R09_RS16690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0R09_RS16705	COG0833	amino acid
C0R09_RS16710	COG2311	Membrane
C0R09_RS16715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0R09_RS16720	COG0492	ferredoxin-NADP+ reductase activity
C0R09_RS16725	COG0494	nUDIX hydrolase
C0R09_RS16735	COG1228	amidohydrolase
C0R09_RS16745	COG4166	transmembrane transport
C0R09_RS16750	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS16755	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS16760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0R09_RS16765	COG0601	transmembrane transport
C0R09_RS16770	COG2814	Major facilitator Superfamily
C0R09_RS16775	COG4948	Mandelate Racemase Muconate Lactonizing
C0R09_RS16780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0R09_RS16785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C0R09_RS16790	COG3599	regulation of cell shape
C0R09_RS16795	COG2302	S4 RNA-binding domain
C0R09_RS16800	COG0762	integral membrane protein
C0R09_RS16805	COG1799	cell septum assembly
C0R09_RS16810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0R09_RS16815	COG1496	oxidoreductase activity
C0R09_RS16820	COG1873	PFAM PRC-barrel domain
C0R09_RS16825	COG1191	sigma factor activity
C0R09_RS16830	COG1191	sigma factor activity
C0R09_RS16840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C0R09_RS16845	COG0849	cell division
C0R09_RS16850	COG3856	small basic protein
C0R09_RS16865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0R09_RS16870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0R09_RS16885	COG0772	Belongs to the SEDS family
C0R09_RS16890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C0R09_RS16895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0R09_RS16905	COG0768	penicillin binding
C0R09_RS16910	COG0768	penicillin binding
C0R09_RS16920	COG0275	rRNA processing
C0R09_RS16925	COG2001	Belongs to the MraZ family
C0R09_RS16930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C0R09_RS16945	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C0R09_RS16960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0R09_RS16970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0R09_RS16975	COG1024	Enoyl-CoA hydratase
C0R09_RS16980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0R09_RS16985	COG0511	ligase activity, forming carbon-carbon bonds
C0R09_RS16990	COG0439	Biotin carboxylase
C0R09_RS16995	COG0454	-acetyltransferase
C0R09_RS17010	COG1393	Belongs to the ArsC family
C0R09_RS17040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0R09_RS17060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0R09_RS17070	COG0667	Aldo Keto reductase
C0R09_RS17110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C0R09_RS17115	COG1217	gtp-binding protein TYPA
C0R09_RS17135	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C0R09_RS17165	COG1982	Orn Lys Arg decarboxylase major
C0R09_RS17200	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0R09_RS17215	COG1473	amidohydrolase
C0R09_RS17220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0R09_RS17225	COG2171	N-acyltransferase activity
C0R09_RS17245	COG1126	abc transporter atp-binding protein
C0R09_RS17250	COG0765	amino acid transport
C0R09_RS17255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0R09_RS17265	COG0393	Putative heavy-metal-binding
C0R09_RS17290	COG0457	Tetratricopeptide repeat
C0R09_RS17290	COG0463	Glycosyl transferase, family 2
C0R09_RS17300	COG1091	dTDP-4-dehydrorhamnose reductase activity
C0R09_RS17310	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C0R09_RS17315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C0R09_RS17320	COG0463	Glycosyl transferase, family 2
C0R09_RS17390	COG2252	PERMEase
C0R09_RS17395	COG0778	Nitroreductase
C0R09_RS17405	COG0737	Belongs to the 5'-nucleotidase family
C0R09_RS17405	COG4085	toxin activity
C0R09_RS17405	COG1525	nuclease
C0R09_RS17435	COG2017	converts alpha-aldose to the beta-anomer
C0R09_RS17475	COG2971	BadF BadG BcrA BcrD
C0R09_RS17480	COG0165	Argininosuccinate lyase
C0R09_RS17485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0R09_RS17495	COG3842	ATPase activity
C0R09_RS17525	COG2378	regulation of single-species biofilm formation
C0R09_RS17530	COG3708	Transcriptional regulator
C0R09_RS17540	COG1378	Sugar-specific transcriptional regulator TrmB
C0R09_RS17545	COG2755	lipolytic protein G-D-S-L family
C0R09_RS17545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0R09_RS17690	COG1396	sequence-specific DNA binding
C0R09_RS17695	COG0577	efflux transmembrane transporter activity
C0R09_RS17700	COG1136	(ABC) transporter
C0R09_RS17705	COG2205	protein histidine kinase activity
C0R09_RS17710	COG0745	RESPONSE REGULATOR receiver
C0R09_RS17740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0R09_RS17750	COG1846	Transcriptional regulator
C0R09_RS17755	COG4585	Histidine kinase
C0R09_RS17760	COG2197	response regulator
C0R09_RS17765	COG2814	Major facilitator Superfamily
C0R09_RS17770	COG0583	DNA-binding transcription factor activity
C0R09_RS17775	COG4221	oxidoreductase activity
C0R09_RS17780	COG0300	oxidoreductase activity
C0R09_RS17785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0R09_RS17795	COG4122	O-methyltransferase activity
C0R09_RS17825	COG0436	Aminotransferase
C0R09_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS17840	COG1733	regulation of RNA biosynthetic process
C0R09_RS17865	COG1227	inorganic diphosphatase activity
C0R09_RS17870	COG2843	Capsule synthesis protein
C0R09_RS17875	COG2814	Major facilitator Superfamily
C0R09_RS17890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0R09_RS17980	COG0488	(ABC) transporter
C0R09_RS17995	COG2819	hydrolase of the alpha beta superfamily
C0R09_RS18000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS18000	COG2207	Transcriptional regulator
C0R09_RS18025	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C0R09_RS18035	COG0714	Associated with various cellular activities
C0R09_RS18060	COG2226	methyltransferase
C0R09_RS18060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS18060	COG3433	isochorismatase activity
C0R09_RS18065	COG3321	synthase
C0R09_RS18065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS18065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0R09_RS18065	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS18065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0R09_RS18075	COG3433	isochorismatase activity
C0R09_RS18075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0R09_RS18075	COG2226	methyltransferase
C0R09_RS18080	COG1021	2,3-dihydroxybenzoate-AMP ligase
C0R09_RS18100	COG1129	ABC transporter
C0R09_RS18105	COG2375	cellular response to nickel ion
C0R09_RS18105	COG1132	(ABC) transporter
C0R09_RS18110	COG1132	(ABC) transporter
C0R09_RS18115	COG0840	transmembrane signaling receptor activity
C0R09_RS18135	COG2962	Rard protein
C0R09_RS18140	COG2140	Oxalate decarboxylase
C0R09_RS18145	COG3186	Phenylalanine-4-hydroxylase
C0R09_RS18155	COG2333	competence protein COMEC
C0R09_RS18155	COG0658	competence protein
C0R09_RS18265	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0R09_RS18305	COG3299	homolog of phage Mu protein gp47
C0R09_RS18385	COG2369	cell adhesion
C0R09_RS18410	COG1595	DNA-templated transcription, initiation
C0R09_RS18460	COG3645	SOS response
C0R09_RS18460	COG3646	Phage regulatory protein
C0R09_RS18475	COG0629	single-stranded DNA binding
C0R09_RS18530	COG1396	sequence-specific DNA binding
C0R09_RS18540	COG0582	viral genome integration into host DNA
C0R09_RS18595	COG3778	Protein conserved in bacteria
C0R09_RS18600	COG3299	homolog of phage Mu protein gp47
C0R09_RS18605	COG3628	GPW Gp25 family protein
C0R09_RS18755	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C0R09_RS18765	COG0756	dUTP diphosphatase activity
C0R09_RS18785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0R09_RS18790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0R09_RS18805	COG2176	DNA-directed DNA polymerase activity
C0R09_RS18820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0R09_RS18820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0R09_RS18960	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C0R09_RS18975	COG0840	transmembrane signaling receptor activity
C0R09_RS18990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0R09_RS18995	COG2382	esterase
C0R09_RS19000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C0R09_RS19020	COG1253	flavin adenine dinucleotide binding
C0R09_RS19025	COG0210	DNA helicase
C0R09_RS19050	COG0861	Integral membrane protein TerC family
C0R09_RS19065	COG0835	chemotaxis
C0R09_RS19075	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C0R09_RS19090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C0R09_RS19095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0R09_RS19100	COG1404	Belongs to the peptidase S8 family
C0R09_RS19105	COG1253	flavin adenine dinucleotide binding
C0R09_RS19115	COG1595	DNA-templated transcription, initiation
C0R09_RS19125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C0R09_RS19130	COG1131	(ABC) transporter
C0R09_RS19135	COG2755	lipolytic protein G-D-S-L family
C0R09_RS19140	COG2211	Major facilitator Superfamily
C0R09_RS19145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0R09_RS19155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0R09_RS19165	COG1285	pathogenesis
C0R09_RS19175	COG2971	BadF BadG BcrA BcrD
C0R09_RS19185	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0R09_RS19195	COG1486	melibiose metabolic process
C0R09_RS19205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0R09_RS19230	COG0739	heme binding
C0R09_RS19235	COG0745	RESPONSE REGULATOR receiver
C0R09_RS19240	COG2205	protein histidine kinase activity
C0R09_RS19245	COG1902	pentaerythritol trinitrate reductase activity
C0R09_RS19245	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0R09_RS19250	COG2084	Dehydrogenase
C0R09_RS19265	COG1316	TRANSCRIPTIONal
C0R09_RS19270	COG0653	protein targeting
C0R09_RS19285	COG0671	phosphoesterase, PA-phosphatase related
C0R09_RS19290	COG1929	Belongs to the glycerate kinase type-1 family
C0R09_RS19295	COG2610	gluconate transmembrane transporter activity
C0R09_RS19300	COG3835	regulator
C0R09_RS19310	COG1910	domain protein
C0R09_RS19315	COG0725	ABC transporter, periplasmic molybdate-binding protein
C0R09_RS19320	COG4149	molybdate abc transporter
C0R09_RS19330	COG3481	metal-dependent phosphohydrolase, HD sub domain
C0R09_RS19340	COG0586	Pfam SNARE associated Golgi protein
C0R09_RS19350	COG1983	PspC domain protein
C0R09_RS19360	COG1510	regulation of RNA biosynthetic process
C0R09_RS19365	COG0517	IMP dehydrogenase activity
C0R09_RS19365	COG4175	Glycine betaine
C0R09_RS19375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0R09_RS19385	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0R09_RS19395	COG0564	pseudouridine synthase activity
C0R09_RS19405	COG0601	transmembrane transport
C0R09_RS19415	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS19420	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS19425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C0R09_RS19440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C0R09_RS19445	COG3874	Sporulation protein YtfJ
C0R09_RS19455	COG1388	LysM domain
C0R09_RS19455	COG3584	3D domain protein
C0R09_RS19470	COG0861	Integral membrane protein TerC family
C0R09_RS19475	COG5002	protein histidine kinase activity
C0R09_RS19570	COG0301	tRNA thio-modification
C0R09_RS19575	COG1104	cysteine desulfurase activity
C0R09_RS19580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C0R09_RS19590	COG4709	membrane
C0R09_RS19595	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C0R09_RS19625	COG4221	oxidoreductase activity
C0R09_RS19635	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0R09_RS19645	COG4326	sporulation control protein
C0R09_RS19670	COG1363	Peptidase, m42
C0R09_RS19675	COG2081	HI0933 family
C0R09_RS19685	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C0R09_RS19690	COG1309	transcriptional regulator
C0R09_RS19695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0R09_RS19700	COG2203	Gaf domain
C0R09_RS19700	COG2199	diguanylate cyclase activity
C0R09_RS19705	COG0406	alpha-ribazole phosphatase activity
C0R09_RS19715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C0R09_RS19720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0R09_RS19725	COG0454	-acetyltransferase
C0R09_RS19730	COG0517	IMP dehydrogenase activity
C0R09_RS19735	COG0123	including yeast histone deacetylase and acetoin utilization protein
C0R09_RS19740	COG2514	catechol 2,3-dioxygenase activity
C0R09_RS19750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C0R09_RS19755	COG1609	Transcriptional regulator
C0R09_RS19760	COG1605	Chorismate mutase
C0R09_RS19760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C0R09_RS19765	COG0849	cell division
C0R09_RS19770	COG3118	belongs to the thioredoxin family
C0R09_RS19785	COG2309	aminopeptidase activity
C0R09_RS19795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0R09_RS19800	COG2059	Chromate
C0R09_RS19805	COG2059	Chromate
C0R09_RS19840	COG0436	Aminotransferase
C0R09_RS19850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0R09_RS19865	COG1595	DNA-templated transcription, initiation
C0R09_RS19875	COG0315	cyclic pyranopterin monophosphate synthase activity
C0R09_RS19880	COG0314	molybdopterin synthase activity
C0R09_RS19885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0R09_RS19890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0R09_RS19905	COG1414	Transcriptional regulator
C0R09_RS19915	COG1674	ftsk spoiiie
C0R09_RS19930	COG0528	UMP kinase activity
C0R09_RS19945	COG0697	spore germination
C0R09_RS19950	COG0681	Belongs to the peptidase S26 family
C0R09_RS19955	COG0129	dihydroxy-acid dehydratase activity
C0R09_RS19960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C0R09_RS19975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0R09_RS20025	COG1120	ATPase activity
C0R09_RS20030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0R09_RS20055	COG0483	inositol monophosphate 1-phosphatase activity
C0R09_RS20075	COG1966	Carbon starvation protein
C0R09_RS20080	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C0R09_RS20085	COG2226	methyltransferase
C0R09_RS20095	COG2814	Major facilitator Superfamily
C0R09_RS20105	COG1566	PFAM secretion protein HlyD family protein
C0R09_RS20110	COG1846	Transcriptional regulator
C0R09_RS20125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0R09_RS20130	COG2357	RelA SpoT domain protein
C0R09_RS20135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0R09_RS20135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0R09_RS20140	COG1309	transcriptional regulator
C0R09_RS20145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C0R09_RS20150	COG0826	peptidase U32
C0R09_RS20155	COG4840	Belongs to the UPF0435 family
C0R09_RS20160	COG4946	Tricorn protease homolog
C0R09_RS20160	COG0823	Involved in the tonB-independent uptake of proteins
C0R09_RS20160	COG1506	peptidase
C0R09_RS20165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0R09_RS20175	COG1473	amidohydrolase
C0R09_RS20180	COG1278	Cold shock
C0R09_RS20185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C0R09_RS20190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C0R09_RS20230	COG1309	transcriptional regulator
C0R09_RS20235	COG0318	PFAM AMP-dependent synthetase and ligase
C0R09_RS20250	COG5002	protein histidine kinase activity
C0R09_RS20255	COG4191	Histidine kinase
C0R09_RS20275	COG0726	polysaccharide deacetylase
C0R09_RS20280	COG4129	membrane
C0R09_RS20290	COG1609	Transcriptional regulator
C0R09_RS20295	COG0561	phosphatase activity
C0R09_RS20305	COG1349	DNA-binding transcription factor activity
C0R09_RS20315	COG2313	pseudouridylate synthase activity
C0R09_RS20320	COG1288	antiporter activity
C0R09_RS20335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0R09_RS20335	COG1263	PTS System
C0R09_RS20340	COG0363	glucosamine-6-phosphate deaminase activity
C0R09_RS20350	COG3711	transcriptional antiterminator
C0R09_RS20365	COG1879	ABC-type sugar transport system periplasmic component
C0R09_RS20370	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0R09_RS20375	COG1129	ABC transporter
C0R09_RS20380	COG1869	D-ribose catabolic process
C0R09_RS20385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0R09_RS20390	COG1609	Transcriptional regulator
C0R09_RS20395	COG1307	EDD domain protein, DegV family
C0R09_RS20400	COG1228	amidohydrolase
C0R09_RS20405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C0R09_RS20410	COG2207	Transcriptional regulator
C0R09_RS20415	COG1027	Aspartate ammonia-lyase
C0R09_RS20420	COG3253	May function as heme-dependent peroxidase
C0R09_RS20425	COG1072	(Pantothenic acid kinase))
C0R09_RS20435	COG4533	DNA binding
C0R09_RS20440	COG2814	Major facilitator Superfamily
C0R09_RS20440	COG0477	Major facilitator Superfamily
C0R09_RS20445	COG2814	Major facilitator Superfamily
C0R09_RS20450	COG2843	Capsule synthesis protein
C0R09_RS20485	COG3620	sequence-specific DNA binding
C0R09_RS20510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0R09_RS20515	COG1832	CoA-binding protein
C0R09_RS20520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0R09_RS20530	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C0R09_RS20535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS20540	COG3584	3D domain protein
C0R09_RS20560	COG1252	NADH dehydrogenase
C0R09_RS20570	COG1842	Phage shock protein A
C0R09_RS20595	COG0316	Belongs to the HesB IscA family
C0R09_RS20605	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C0R09_RS20610	COG4844	belongs to the
C0R09_RS20615	COG1252	NADH dehydrogenase
C0R09_RS20635	COG4837	Protein of unknown function (DUF1462)
C0R09_RS20640	COG0626	cystathionine gamma-synthase activity
C0R09_RS20645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0R09_RS20650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C0R09_RS20660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0R09_RS20670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0R09_RS20675	COG0647	UMP catabolic process
C0R09_RS20685	COG2445	Protein of unknown function DUF86
C0R09_RS20690	COG1494	fructose-1,6-bisphosphatase
C0R09_RS20700	COG4470	Protein conserved in bacteria
C0R09_RS20710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C0R09_RS20720	COG0420	3'-5' exonuclease activity
C0R09_RS20730	COG0739	heme binding
C0R09_RS20735	COG0598	Magnesium transport protein CorA
C0R09_RS20745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0R09_RS20755	COG3377	Domain of unknown function (DUF1805)
C0R09_RS20760	COG0730	response to heat
C0R09_RS20765	COG1801	Protein of unknown function DUF72
C0R09_RS20775	COG1744	ABC transporter substrate-binding protein PnrA-like
C0R09_RS20780	COG1744	ABC transporter substrate-binding protein PnrA-like
C0R09_RS20790	COG2608	mercury ion transmembrane transporter activity
C0R09_RS20795	COG2268	Band 7 protein
C0R09_RS20860	COG0719	Fe-S assembly protein
C0R09_RS20865	COG0822	iron-sulfur transferase activity
C0R09_RS20870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0R09_RS20875	COG0719	Fe-S assembly protein
C0R09_RS20880	COG0396	ATPase activity
C0R09_RS20890	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C0R09_RS20910	COG5002	protein histidine kinase activity
C0R09_RS20915	COG0745	RESPONSE REGULATOR receiver
C0R09_RS20930	COG0509	glycine decarboxylation via glycine cleavage system
C0R09_RS20935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0R09_RS20940	COG0450	alkyl hydroperoxide reductase
C0R09_RS20945	COG1393	Belongs to the ArsC family
C0R09_RS20980	COG1396	sequence-specific DNA binding
C0R09_RS20985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0R09_RS21000	COG2217	Heavy metal translocating P-type atpase
C0R09_RS21005	COG0477	Major facilitator Superfamily
C0R09_RS21010	COG1132	(ABC) transporter
C0R09_RS21015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0R09_RS21020	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C0R09_RS21030	COG1850	ribulose-bisphosphate carboxylase activity
C0R09_RS21035	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C0R09_RS21040	COG0235	Class ii aldolase
C0R09_RS21045	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C0R09_RS21060	COG2190	(PTS) system
C0R09_RS21060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0R09_RS21060	COG1263	PTS System
C0R09_RS21070	COG1609	Transcriptional regulator
C0R09_RS21075	COG1960	acyl-CoA dehydrogenase activity
C0R09_RS21080	COG0183	Belongs to the thiolase family
C0R09_RS21085	COG1024	Enoyl-CoA hydratase
C0R09_RS21085	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0R09_RS21100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0R09_RS21105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C0R09_RS21125	COG5577	PFAM Coat F domain
C0R09_RS21140	COG1309	transcriptional regulator
C0R09_RS21150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C0R09_RS21155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0R09_RS21160	COG0167	dihydroorotate dehydrogenase activity
C0R09_RS21165	COG0686	Belongs to the AlaDH PNT family
C0R09_RS21170	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0R09_RS21170	COG2508	Transcriptional regulator
C0R09_RS21175	COG2814	Major facilitator Superfamily
C0R09_RS21185	COG0535	radical SAM domain protein
C0R09_RS21190	COG1506	peptidase
C0R09_RS21195	COG1098	S1 RNA binding domain
C0R09_RS21200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C0R09_RS21210	COG0561	phosphatase activity
C0R09_RS21215	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0R09_RS21220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0R09_RS21230	COG0788	formyltetrahydrofolate deformylase activity
C0R09_RS21245	COG1074	ATP-dependent DNA helicase activity
C0R09_RS21250	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C0R09_RS21255	COG0419	ATPase involved in DNA repair
C0R09_RS21260	COG0420	3'-5' exonuclease activity
C0R09_RS21270	COG1612	heme a metabolic process
C0R09_RS21275	COG0109	protoheme IX farnesyltransferase activity
C0R09_RS21280	COG0730	response to heat
C0R09_RS21310	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS21310	COG1454	alcohol dehydrogenase
C0R09_RS21320	COG1028	Short-chain dehydrogenase reductase Sdr
C0R09_RS21325	COG2610	gluconate transmembrane transporter activity
C0R09_RS21330	COG3829	transcription factor binding
C0R09_RS21330	COG3290	protein histidine kinase activity
C0R09_RS21335	COG2340	Cysteine-rich secretory protein family
C0R09_RS21350	COG1940	carbohydrate kinase activity
C0R09_RS21355	COG2076	Multidrug Resistance protein
C0R09_RS21365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C0R09_RS21380	COG0716	FMN binding
C0R09_RS21390	COG2814	Major facilitator Superfamily
C0R09_RS21395	COG1566	PFAM secretion protein HlyD family protein
C0R09_RS21400	COG1309	transcriptional regulator
C0R09_RS21425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS21430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS21435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS21445	COG4608	Belongs to the ABC transporter superfamily
C0R09_RS21450	COG0444	Belongs to the ABC transporter superfamily
C0R09_RS21455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0R09_RS21460	COG0601	transmembrane transport
C0R09_RS21470	COG2205	protein histidine kinase activity
C0R09_RS21475	COG0745	RESPONSE REGULATOR receiver
C0R09_RS21485	COG4895	conserved protein (DUF2196)
C0R09_RS21505	COG0384	phenazine biosynthesis protein PhzF
C0R09_RS21515	COG5566	PFAM Mor transcription activator
C0R09_RS21585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C0R09_RS21590	COG0557	exoribonuclease II activity
C0R09_RS21595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0R09_RS21600	COG2010	Cytochrome c
C0R09_RS21610	COG0148	phosphopyruvate hydratase activity
C0R09_RS21620	COG0149	triose-phosphate isomerase activity
C0R09_RS21625	COG0126	phosphoglycerate kinase activity
C0R09_RS21630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0R09_RS21645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C0R09_RS21670	COG1595	DNA-templated transcription, initiation
C0R09_RS21685	COG0740	serine-type endopeptidase activity
C0R09_RS21695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0R09_RS21700	COG1481	regulation of sporulation
C0R09_RS21705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C0R09_RS21710	COG1660	Displays ATPase and GTPase activities
C0R09_RS21715	COG0492	ferredoxin-NADP+ reductase activity
C0R09_RS21765	COG0140	phosphoribosyl-ATP diphosphatase activity
C0R09_RS21765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0R09_RS21770	COG0107	imidazoleglycerol-phosphate synthase activity
C0R09_RS21775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C0R09_RS21780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C0R09_RS21785	COG0131	Imidazoleglycerol-phosphate dehydratase
C0R09_RS21790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C0R09_RS21795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C0R09_RS21800	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C0R09_RS21805	COG0110	maltose O-acetyltransferase activity
C0R09_RS21810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C0R09_RS21815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0R09_RS21820	COG0556	nucleotide-excision repair
C0R09_RS21825	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C0R09_RS21830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0R09_RS21835	COG0793	Belongs to the peptidase S41A family
C0R09_RS21835	COG3409	Peptidoglycan-binding domain 1 protein
C0R09_RS21840	COG0739	heme binding
C0R09_RS21845	COG2177	Part of the ABC transporter FtsEX involved in
C0R09_RS21850	COG2884	Cell division ATP-binding protein ftsE
C0R09_RS21855	COG0165	Argininosuccinate lyase
C0R09_RS21860	COG0137	argininosuccinate synthase activity
C0R09_RS21865	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C0R09_RS21870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0R09_RS21875	COG0505	Belongs to the CarA family
C0R09_RS21880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0R09_RS21885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0R09_RS21890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C0R09_RS21895	COG2010	Cytochrome c
C0R09_RS21925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0R09_RS21930	COG0653	protein targeting
C0R09_RS21935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C0R09_RS21940	COG1278	Cold shock
C0R09_RS21950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0R09_RS21970	COG1516	flagellar protein fliS
C0R09_RS21975	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C0R09_RS21980	COG1334	flagellar protein FlaG
C0R09_RS21995	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C0R09_RS22000	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C0R09_RS22010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0R09_RS22015	COG1256	bacterial-type flagellum assembly
C0R09_RS22015	COG4786	Flagellar basal body rod
C0R09_RS22035	COG0024	Methionine aminopeptidase
C0R09_RS22040	COG1040	competence protein
C0R09_RS22045	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C0R09_RS22065	COG1649	PFAM Uncharacterised BCR, COG1649
C0R09_RS22065	COG0726	polysaccharide deacetylase
C0R09_RS22070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0R09_RS22100	COG1309	transcriptional regulator
C0R09_RS22105	COG0534	Mate efflux family protein
C0R09_RS22110	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0R09_RS22115	COG2373	Large extracellular alpha-helical protein
C0R09_RS22125	COG1739	Uncharacterized protein family UPF0029
C0R09_RS22130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0R09_RS22145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0R09_RS22160	COG4786	Flagellar basal body rod
C0R09_RS22170	COG1609	Transcriptional regulator
C0R09_RS22175	COG0739	heme binding
C0R09_RS22180	COG2385	sporulation resulting in formation of a cellular spore
C0R09_RS22185	COG0436	Aminotransferase
C0R09_RS22190	COG1522	sequence-specific DNA binding
C0R09_RS22195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0R09_RS22205	COG4836	Membrane
C0R09_RS22210	COG1007	ATP synthesis coupled electron transport
C0R09_RS22215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0R09_RS22220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0R09_RS22225	COG0713	ATP synthesis coupled electron transport
C0R09_RS22235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0R09_RS22240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C0R09_RS22245	COG0649	NAD binding
C0R09_RS22250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0R09_RS22255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0R09_RS22260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0R09_RS22265	COG1404	Belongs to the peptidase S8 family
C0R09_RS22275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C0R09_RS22280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C0R09_RS22285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C0R09_RS22290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C0R09_RS22295	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C0R09_RS22310	COG0356	it plays a direct role in the translocation of protons across the membrane
C0R09_RS22330	COG1361	Conserved repeat domain
C0R09_RS22335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C0R09_RS22340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C0R09_RS22350	COG4475	Protein of unknown function (DUF436)
C0R09_RS22355	COG0698	ribose 5-phosphate isomerase
C0R09_RS22365	COG1971	Probably functions as a manganese efflux pump
C0R09_RS22370	COG0009	L-threonylcarbamoyladenylate synthase
C0R09_RS22385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C0R09_RS22400	COG0254	rRNA binding
C0R09_RS22410	COG1388	LysM domain
C0R09_RS22410	COG3584	3D domain protein
C0R09_RS22415	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C0R09_RS22420	COG1494	fructose-1,6-bisphosphatase
C0R09_RS22425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0R09_RS22430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0R09_RS22435	COG0191	fructose-bisphosphate aldolase activity
C0R09_RS22440	COG2204	response regulator
C0R09_RS22445	COG0504	CTP synthase activity
C0R09_RS22450	COG3343	RNA polymerase activity
C0R09_RS22455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C0R09_RS22455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C0R09_RS22455	COG1703	isobutyryl-CoA mutase activity
C0R09_RS22470	COG1960	acyl-CoA dehydrogenase activity
C0R09_RS22475	COG1960	acyl-CoA dehydrogenase activity
C0R09_RS22480	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0R09_RS22485	COG0183	Belongs to the thiolase family
C0R09_RS22490	COG2181	nitrate reductase activity
C0R09_RS22490	COG0247	lactate metabolic process
C0R09_RS22495	COG1509	lysine 2,3-aminomutase activity
C0R09_RS22500	COG3829	transcription factor binding
C0R09_RS22520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C0R09_RS22525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0R09_RS22540	COG3465	dGTPase activity
C0R09_RS22545	COG1078	dGTPase activity
C0R09_RS22550	COG0564	pseudouridine synthase activity
C0R09_RS22555	COG2309	aminopeptidase activity
C0R09_RS22570	COG3693	PFAM glycoside hydrolase, family 10
C0R09_RS22575	COG0116	Belongs to the methyltransferase superfamily
C0R09_RS22580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0R09_RS22585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS22590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS22595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0R09_RS22615	COG1177	transmembrane transport
C0R09_RS22620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C0R09_RS22635	COG0527	aspartate kinase activity
C0R09_RS22640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0R09_RS22645	COG0753	catalase activity
C0R09_RS22660	COG1132	(ABC) transporter
C0R09_RS22665	COG1132	(ABC) transporter
C0R09_RS22670	COG1012	belongs to the aldehyde dehydrogenase family
C0R09_RS22680	COG1297	OPT oligopeptide transporter protein
C0R09_RS22685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C0R09_RS22690	COG0303	'Molybdopterin
C0R09_RS22695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C0R09_RS22705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C0R09_RS22730	COG1131	(ABC) transporter
C0R09_RS22745	COG0084	hydrolase, TatD family'
C0R09_RS22750	COG1115	amino acid carrier protein
C0R09_RS22765	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0R09_RS22780	COG0531	amino acid
C0R09_RS22785	COG0584	glycerophosphoryl diester phosphodiesterase
C0R09_RS22790	COG1653	transport
C0R09_RS22795	COG0395	ABC-type sugar transport system, permease component
C0R09_RS22805	COG3842	ATPase activity
C0R09_RS22820	COG0840	transmembrane signaling receptor activity
C0R09_RS22850	COG2205	protein histidine kinase activity
C0R09_RS22855	COG0488	(ABC) transporter
C0R09_RS22860	COG0277	FAD linked oxidase domain protein
C0R09_RS22865	COG0737	Belongs to the 5'-nucleotidase family
C0R09_RS22870	COG0514	ATP-dependent DNA helicase (RecQ)
C0R09_RS22875	COG2208	phosphoserine phosphatase activity
C0R09_RS22885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0R09_RS22890	COG2198	Histidine kinase
C0R09_RS22890	COG2205	protein histidine kinase activity
C0R09_RS22890	COG0784	Response regulator, receiver
C0R09_RS22895	COG0457	Tetratricopeptide repeat
C0R09_RS22895	COG0463	Glycosyl transferase, family 2
C0R09_RS22900	COG1187	pseudouridine synthase activity
C0R09_RS22905	COG0861	Integral membrane protein TerC family
C0R09_RS22910	COG2814	Major facilitator Superfamily
C0R09_RS22935	COG1595	DNA-templated transcription, initiation
C0R09_RS22960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0R09_RS22965	COG1482	cell wall glycoprotein biosynthetic process
C0R09_RS22970	COG0745	RESPONSE REGULATOR receiver
C0R09_RS22990	COG2271	Major facilitator Superfamily
C0R09_RS22995	COG0784	Response regulator, receiver
C0R09_RS23000	COG4191	Histidine kinase
C0R09_RS23005	COG0765	amino acid transport
C0R09_RS23010	COG0765	amino acid transport
C0R09_RS23025	COG1649	PFAM Uncharacterised BCR, COG1649
C0R09_RS23030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0R09_RS23040	COG0840	transmembrane signaling receptor activity
C0R09_RS23045	COG2226	methyltransferase
C0R09_RS23050	COG2226	methyltransferase
C0R09_RS23050	COG1073	alpha beta
C0R09_RS23055	COG0653	protein targeting
C0R09_RS23060	COG3239	Fatty acid desaturase
C0R09_RS23065	COG2819	hydrolase of the alpha beta superfamily
C0R09_RS23115	COG0840	transmembrane signaling receptor activity
C0R09_RS23130	COG1595	DNA-templated transcription, initiation
C0R09_RS23135	COG0561	phosphatase activity
C0R09_RS23145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0R09_RS23185	COG1733	regulation of RNA biosynthetic process
C0R09_RS23190	COG2814	Major facilitator Superfamily
C0R09_RS23195	COG0656	L-ascorbic acid biosynthetic process
C0R09_RS23200	COG1151	hydroxylamine reductase activity
C0R09_RS23210	COG0579	oxidoreductase
C0R09_RS23230	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C0R09_RS23250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0R09_RS23260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C0R09_RS23265	COG4853	Protein conserved in bacteria
C0R09_RS23270	COG4863	YycH protein
C0R09_RS23275	COG5002	protein histidine kinase activity
C0R09_RS23285	COG0739	heme binding
C0R09_RS23300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0R09_RS23305	COG0305	Participates in initiation and elongation during chromosome replication
C0R09_RS23310	COG0359	binds to the 23S rRNA
C0R09_RS23315	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C0R09_RS23325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C0R09_RS23330	COG0629	single-stranded DNA binding
C0R09_RS23335	COG0360	Binds together with S18 to 16S ribosomal RNA
C0R09_RS23340	COG0012	GTP binding
C0R09_RS23350	COG1164	Oligoendopeptidase f
C0R09_RS23355	COG4481	Protein conserved in bacteria
C0R09_RS23360	COG0668	transmembrane transport
C0R09_RS23375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0R09_RS23380	COG1475	DNA binding
C0R09_RS23385	COG1192	Involved in chromosome partitioning
C0R09_RS23390	COG1475	DNA binding
C0R09_RS23395	COG0357	Ribosomal RNA small subunit methyltransferase G
C0R09_RS23400	COG0445	tRNA wobble uridine modification
C0R09_RS23405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C0R09_RS23410	COG1847	R3H domain protein
C0R09_RS23415	COG0706	membrane insertase activity
C0R09_RS23420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C0R09_RS23425	COG0594	ribonuclease P activity
C0R09_RS23430	COG0230	Belongs to the bacterial ribosomal protein bL34 family