locus-tag	class	description
GOP56_RS00015	COG1702	phosphate starvation-inducible protein PhoH
GOP56_RS00020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GOP56_RS00025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GOP56_RS00030	COG0295	cytidine deaminase activity
GOP56_RS00035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GOP56_RS00045	COG1381	Involved in DNA repair and RecF pathway recombination
GOP56_RS00050	COG0517	IMP dehydrogenase activity
GOP56_RS00055	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GOP56_RS00060	COG0358	DNA primase activity
GOP56_RS00065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOP56_RS00075	COG1960	acyl-CoA dehydrogenase activity
GOP56_RS00080	COG2384	SAM-dependent methyltransferase
GOP56_RS00085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GOP56_RS00100	COG0793	Belongs to the peptidase S41A family
GOP56_RS00160	COG1242	4 iron, 4 sulfur cluster binding
GOP56_RS00170	COG0584	glycerophosphoryl diester phosphodiesterase
GOP56_RS00175	COG0456	acetyltransferase
GOP56_RS00185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GOP56_RS00190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GOP56_RS00195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GOP56_RS00200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOP56_RS00220	COG1309	transcriptional regulator
GOP56_RS00225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOP56_RS00240	COG2249	NAD(P)H dehydrogenase (quinone) activity
GOP56_RS00260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GOP56_RS00270	COG0351	phosphomethylpyrimidine kinase
GOP56_RS00290	COG1428	Deoxynucleoside kinase
GOP56_RS00295	COG1428	Deoxynucleoside kinase
GOP56_RS00315	COG1607	acyl-coa hydrolase
GOP56_RS00330	COG2986	histidine ammonia-lyase
GOP56_RS00340	COG4294	response to UV
GOP56_RS00370	COG1388	LysM domain
GOP56_RS00375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GOP56_RS00385	COG0535	radical SAM domain protein
GOP56_RS00400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GOP56_RS00405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOP56_RS00415	COG0367	asparagine synthase
GOP56_RS00420	COG5002	protein histidine kinase activity
GOP56_RS00425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GOP56_RS00435	COG0018	arginyl-trna synthetase
GOP56_RS00455	COG1410	methionine synthase
GOP56_RS00455	COG0646	methionine synthase
GOP56_RS00460	COG0646	methionine synthase
GOP56_RS00460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GOP56_RS00475	COG2116	formate transmembrane transporter activity
GOP56_RS00480	COG0697	spore germination
GOP56_RS00485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GOP56_RS00495	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GOP56_RS00515	COG1122	ATPase activity
GOP56_RS00520	COG1122	ATPase activity
GOP56_RS00545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GOP56_RS00575	COG1846	Transcriptional regulator
GOP56_RS00580	COG2814	Major facilitator Superfamily
GOP56_RS00590	COG2814	Major facilitator Superfamily
GOP56_RS00595	COG0640	Transcriptional regulator
GOP56_RS00600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GOP56_RS00605	COG1116	anion transmembrane transporter activity
GOP56_RS00610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GOP56_RS00615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GOP56_RS00635	COG0640	Transcriptional regulator
GOP56_RS00640	COG0798	PFAM Bile acid sodium symporter
GOP56_RS00660	COG1234	tRNA 3'-trailer cleavage
GOP56_RS00670	COG0697	spore germination
GOP56_RS00675	COG0583	DNA-binding transcription factor activity
GOP56_RS00705	COG1671	Belongs to the UPF0178 family
GOP56_RS00710	COG0671	phosphoesterase, PA-phosphatase related
GOP56_RS00730	COG1294	oxidase, subunit
GOP56_RS00735	COG1271	oxidase subunit
GOP56_RS00775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GOP56_RS00780	COG4838	Belongs to the UPF0358 family
GOP56_RS00785	COG0387	Pfam Sodium calcium exchanger
GOP56_RS00800	COG1302	Protein conserved in bacteria
GOP56_RS00805	COG0772	Belongs to the SEDS family
GOP56_RS00815	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GOP56_RS00820	COG1525	nuclease
GOP56_RS00845	COG3679	Belongs to the UPF0342 family
GOP56_RS00850	COG4471	UPF0298 protein
GOP56_RS00855	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GOP56_RS00870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GOP56_RS00895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOP56_RS00900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GOP56_RS00905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GOP56_RS00910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GOP56_RS00915	COG0840	transmembrane signaling receptor activity
GOP56_RS00920	COG0095	Lipoate-protein ligase
GOP56_RS00960	COG2323	membrane
GOP56_RS00970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS00975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS00980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS00980	COG2207	Transcriptional regulator
GOP56_RS00990	COG2195	Cleaves the N-terminal amino acid of tripeptides
GOP56_RS01010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS01010	COG3711	transcriptional antiterminator
GOP56_RS01015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GOP56_RS01015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS01015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GOP56_RS01020	COG0745	RESPONSE REGULATOR receiver
GOP56_RS01025	COG5002	protein histidine kinase activity
GOP56_RS01030	COG0772	Belongs to the SEDS family
GOP56_RS01050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GOP56_RS01055	COG0628	permease
GOP56_RS01060	COG1376	ErfK ybiS ycfS ynhG family protein
GOP56_RS01065	COG2814	Major facilitator Superfamily
GOP56_RS01075	COG2217	Heavy metal translocating P-type atpase
GOP56_RS01080	COG1271	oxidase subunit
GOP56_RS01085	COG1294	oxidase, subunit
GOP56_RS01090	COG4988	ABC transporter
GOP56_RS01095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GOP56_RS01125	COG0745	RESPONSE REGULATOR receiver
GOP56_RS01130	COG2205	protein histidine kinase activity
GOP56_RS01145	COG2390	Transcriptional regulator
GOP56_RS01155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GOP56_RS01165	COG0431	NADPH-dependent FMN reductase
GOP56_RS01170	COG1321	iron dependent repressor
GOP56_RS01175	COG1752	Esterase of the alpha-beta hydrolase superfamily
GOP56_RS01185	COG3872	metal-dependent enzyme
GOP56_RS01195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GOP56_RS01200	COG0006	proline dipeptidase activity
GOP56_RS01205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GOP56_RS01225	COG2707	UPF0756 membrane protein
GOP56_RS01230	COG2045	Belongs to the ComB family
GOP56_RS01235	COG1809	phosphosulfolactate synthase activity
GOP56_RS01250	COG3854	ATPases associated with a variety of cellular activities
GOP56_RS01290	COG0511	ligase activity, forming carbon-carbon bonds
GOP56_RS01295	COG0439	Biotin carboxylase
GOP56_RS01300	COG1302	Protein conserved in bacteria
GOP56_RS01315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GOP56_RS01320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GOP56_RS01325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GOP56_RS01330	COG1570	exodeoxyribonuclease VII activity
GOP56_RS01335	COG1722	exodeoxyribonuclease VII activity
GOP56_RS01345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GOP56_RS01350	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GOP56_RS01360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GOP56_RS01365	COG1438	arginine binding
GOP56_RS01370	COG0497	DNA recombination
GOP56_RS01455	COG1136	(ABC) transporter
GOP56_RS01455	COG0577	efflux transmembrane transporter activity
GOP56_RS01475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS01480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOP56_RS01480	COG2070	2-Nitropropane dioxygenase
GOP56_RS01485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS01490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOP56_RS01495	COG3425	synthase
GOP56_RS01500	COG1024	Enoyl-CoA hydratase
GOP56_RS01510	COG1357	PFAM Pentapeptide repeats (8 copies)
GOP56_RS01515	COG4221	oxidoreductase activity
GOP56_RS01515	COG3321	synthase
GOP56_RS01515	COG0300	oxidoreductase activity
GOP56_RS01515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS01520	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS01520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS01520	COG0300	oxidoreductase activity
GOP56_RS01520	COG3321	synthase
GOP56_RS01525	COG3321	synthase
GOP56_RS01525	COG4221	oxidoreductase activity
GOP56_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS01525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS01535	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GOP56_RS01570	COG0750	zinc metalloprotease
GOP56_RS01575	COG0745	RESPONSE REGULATOR receiver
GOP56_RS01585	COG2124	cytochrome p450
GOP56_RS01585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GOP56_RS01590	COG3191	aminopeptidase activity
GOP56_RS01605	COG1285	pathogenesis
GOP56_RS01610	COG0180	Tryptophanyl-tRNA synthetase
GOP56_RS01620	COG1316	TRANSCRIPTIONal
GOP56_RS01625	COG0745	RESPONSE REGULATOR receiver
GOP56_RS01640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOP56_RS01640	COG2755	lipolytic protein G-D-S-L family
GOP56_RS01645	COG1566	PFAM secretion protein HlyD family protein
GOP56_RS01650	COG1136	(ABC) transporter
GOP56_RS01655	COG0577	efflux transmembrane transporter activity
GOP56_RS01665	COG1595	DNA-templated transcription, initiation
GOP56_RS01690	COG1215	transferase activity, transferring glycosyl groups
GOP56_RS01705	COG3290	protein histidine kinase activity
GOP56_RS01705	COG3829	transcription factor binding
GOP56_RS01715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GOP56_RS01720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GOP56_RS01725	COG0022	dehydrogenase e1 component
GOP56_RS01730	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOP56_RS01740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GOP56_RS01740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GOP56_RS01745	COG0346	lactoylglutathione lyase activity
GOP56_RS01750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GOP56_RS01755	COG2195	Cleaves the N-terminal amino acid of tripeptides
GOP56_RS01770	COG0494	nUDIX hydrolase
GOP56_RS01775	COG1379	DNA repair
GOP56_RS01780	COG1300	Membrane
GOP56_RS01785	COG0735	belongs to the Fur family
GOP56_RS01795	COG4974	Belongs to the 'phage' integrase family
GOP56_RS01800	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GOP56_RS01825	COG3842	ATPase activity
GOP56_RS01830	COG1176	ABC-type spermidine putrescine transport system, permease component I
GOP56_RS01835	COG1177	transmembrane transport
GOP56_RS01840	COG2195	Cleaves the N-terminal amino acid of tripeptides
GOP56_RS01850	COG0601	transmembrane transport
GOP56_RS01855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GOP56_RS01860	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS01865	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS01870	COG0840	transmembrane signaling receptor activity
GOP56_RS01875	COG1686	Belongs to the peptidase S11 family
GOP56_RS01885	COG2172	sigma factor antagonist activity
GOP56_RS01910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOP56_RS01925	COG0697	spore germination
GOP56_RS01930	COG0019	diaminopimelate decarboxylase activity
GOP56_RS01935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GOP56_RS02020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GOP56_RS02025	COG1846	Transcriptional regulator
GOP56_RS02035	COG1114	Component of the transport system for branched-chain amino acids
GOP56_RS02070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GOP56_RS02075	COG1994	Peptidase M50
GOP56_RS02080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GOP56_RS02085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GOP56_RS02090	COG1686	Belongs to the peptidase S11 family
GOP56_RS02095	COG2715	membrane protein required for spore maturation
GOP56_RS02100	COG0700	Nucleoside recognition
GOP56_RS02105	COG1187	pseudouridine synthase activity
GOP56_RS02110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOP56_RS02115	COG1333	cytochrome c biogenesis protein
GOP56_RS02120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GOP56_RS02125	COG0745	RESPONSE REGULATOR receiver
GOP56_RS02130	COG5002	protein histidine kinase activity
GOP56_RS02140	COG2814	Major facilitator Superfamily
GOP56_RS02155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GOP56_RS02165	COG1141	Ferredoxin
GOP56_RS02180	COG0514	ATP-dependent DNA helicase (RecQ)
GOP56_RS02185	COG1266	CAAX protease self-immunity
GOP56_RS02195	COG0492	ferredoxin-NADP+ reductase activity
GOP56_RS02200	COG4862	establishment of competence for transformation
GOP56_RS02205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GOP56_RS02210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GOP56_RS02220	COG2339	peptidase activity
GOP56_RS02230	COG2959	enzyme of heme biosynthesis
GOP56_RS02245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GOP56_RS02255	COG0539	negative regulation of cytoplasmic translation
GOP56_RS02275	COG1160	GTP binding
GOP56_RS02280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GOP56_RS02285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GOP56_RS02320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GOP56_RS02330	COG0302	gtp cyclohydrolase
GOP56_RS02355	COG0741	lytic transglycosylase activity
GOP56_RS02370	COG3414	Phosphotransferase system galactitol-specific IIB component
GOP56_RS02375	COG3775	system Galactitol-specific IIC component
GOP56_RS02380	COG2213	PTS system mannitol-specific
GOP56_RS02380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS02385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GOP56_RS02390	COG0022	dehydrogenase e1 component
GOP56_RS02390	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOP56_RS02400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GOP56_RS02405	COG2390	Transcriptional regulator
GOP56_RS02420	COG0142	geranyltranstransferase activity
GOP56_RS02430	COG0109	protoheme IX farnesyltransferase activity
GOP56_RS02430	COG1612	heme a metabolic process
GOP56_RS02435	COG0163	prenyltransferase activity
GOP56_RS02445	COG0142	geranyltranstransferase activity
GOP56_RS02450	COG0105	UTP biosynthetic process
GOP56_RS02455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GOP56_RS02460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GOP56_RS02465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GOP56_RS02480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GOP56_RS02485	COG0134	indole-3-glycerol-phosphate synthase activity
GOP56_RS02490	COG0135	phosphoribosylanthranilate isomerase activity
GOP56_RS02495	COG0133	tryptophan synthase activity
GOP56_RS02500	COG0159	tryptophan synthase activity
GOP56_RS02505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GOP56_RS02510	COG0287	Prephenate dehydrogenase
GOP56_RS02515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GOP56_RS02565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GOP56_RS02585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GOP56_RS02590	COG1694	Mazg nucleotide pyrophosphohydrolase
GOP56_RS02595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GOP56_RS02600	COG1803	Methylglyoxal synthase
GOP56_RS02605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GOP56_RS02610	COG0438	transferase activity, transferring glycosyl groups
GOP56_RS02615	COG0617	tRNA 3'-terminal CCA addition
GOP56_RS02620	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GOP56_RS02620	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GOP56_RS02625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GOP56_RS02630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GOP56_RS02635	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GOP56_RS02645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GOP56_RS02645	COG1199	ATP-dependent helicase activity
GOP56_RS02655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GOP56_RS02660	COG0402	S-adenosylhomocysteine deaminase activity
GOP56_RS02675	COG5353	protein conserved in bacteria
GOP56_RS02685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GOP56_RS02700	COG0436	Aminotransferase
GOP56_RS02705	COG0017	Asparaginyl-tRNA synthetase
GOP56_RS02710	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS02715	COG4605	iron ion homeostasis
GOP56_RS02720	COG4604	ABC transporter, ATP-binding protein
GOP56_RS02725	COG4607	ABC-type enterochelin transport system periplasmic component
GOP56_RS02730	COG3935	DnaD domain protein
GOP56_RS02740	COG0438	transferase activity, transferring glycosyl groups
GOP56_RS02750	COG1215	transferase activity, transferring glycosyl groups
GOP56_RS02755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS02765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GOP56_RS02770	COG1164	Oligoendopeptidase f
GOP56_RS02775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GOP56_RS02780	COG0363	glucosamine-6-phosphate deaminase activity
GOP56_RS02785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOP56_RS02800	COG0604	alcohol dehydrogenase
GOP56_RS02810	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS02815	COG1959	2 iron, 2 sulfur cluster binding
GOP56_RS02820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GOP56_RS02840	COG0066	3-isopropylmalate dehydratase activity
GOP56_RS02845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GOP56_RS02850	COG0583	DNA-binding transcription factor activity
GOP56_RS02855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOP56_RS02860	COG0584	glycerophosphoryl diester phosphodiesterase
GOP56_RS02865	COG0564	pseudouridine synthase activity
GOP56_RS02875	COG0697	spore germination
GOP56_RS02880	COG3069	C4-dicarboxylate transmembrane transporter activity
GOP56_RS02945	COG0659	secondary active sulfate transmembrane transporter activity
GOP56_RS02985	COG1301	dicarboxylic acid transport
GOP56_RS03015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GOP56_RS03020	COG3290	protein histidine kinase activity
GOP56_RS03035	COG0778	Nitroreductase
GOP56_RS03050	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS03055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS03060	COG0367	asparagine synthase
GOP56_RS03065	COG2070	2-Nitropropane dioxygenase
GOP56_RS03065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOP56_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03070	COG3321	synthase
GOP56_RS03070	COG4221	oxidoreductase activity
GOP56_RS03075	COG3321	synthase
GOP56_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03075	COG3321	synthase
GOP56_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03075	COG4221	oxidoreductase activity
GOP56_RS03075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03075	COG4221	oxidoreductase activity
GOP56_RS03080	COG3321	synthase
GOP56_RS03080	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03080	COG0300	oxidoreductase activity
GOP56_RS03080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03085	COG4221	oxidoreductase activity
GOP56_RS03085	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03085	COG3321	synthase
GOP56_RS03095	COG2986	histidine ammonia-lyase
GOP56_RS03100	COG0346	lactoylglutathione lyase activity
GOP56_RS03115	COG3732	PTS system glucitol sorbitol-specific
GOP56_RS03135	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GOP56_RS03160	COG1690	Belongs to the RtcB family
GOP56_RS03165	COG0778	Nitroreductase
GOP56_RS03170	COG2249	NAD(P)H dehydrogenase (quinone) activity
GOP56_RS03175	COG0179	Fumarylacetoacetate (FAA) hydrolase
GOP56_RS03195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS03200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS03205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS03215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GOP56_RS03255	COG3583	domain protein
GOP56_RS03255	COG3584	3D domain protein
GOP56_RS03390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOP56_RS03405	COG4607	ABC-type enterochelin transport system periplasmic component
GOP56_RS03450	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GOP56_RS03470	COG1819	glycosyl
GOP56_RS03480	COG2188	Transcriptional regulator
GOP56_RS03485	COG2723	6-phospho-beta-galactosidase activity
GOP56_RS03510	COG0786	glutamate:sodium symporter activity
GOP56_RS03525	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GOP56_RS03540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS03550	COG3541	Predicted nucleotidyltransferase
GOP56_RS03555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GOP56_RS03575	COG4112	unkown
GOP56_RS03585	COG0641	radical SAM
GOP56_RS03595	COG2364	Membrane
GOP56_RS03605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GOP56_RS03615	COG2723	6-phospho-beta-galactosidase activity
GOP56_RS03620	COG2723	6-phospho-beta-galactosidase activity
GOP56_RS03625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GOP56_RS03635	COG0714	Associated with various cellular activities
GOP56_RS03670	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GOP56_RS03675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GOP56_RS03680	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GOP56_RS03685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GOP56_RS03700	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GOP56_RS03705	COG2357	RelA SpoT domain protein
GOP56_RS03710	COG1027	Aspartate ammonia-lyase
GOP56_RS03715	COG1686	Belongs to the peptidase S11 family
GOP56_RS03725	COG0622	Phosphoesterase
GOP56_RS03730	COG0640	Transcriptional regulator
GOP56_RS03735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GOP56_RS03740	COG1902	pentaerythritol trinitrate reductase activity
GOP56_RS03750	COG0697	spore germination
GOP56_RS03755	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GOP56_RS03760	COG2169	Transcriptional regulator
GOP56_RS03765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GOP56_RS03785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GOP56_RS03800	COG1956	GAF domain-containing protein
GOP56_RS03810	COG2197	response regulator
GOP56_RS03850	COG3173	Aminoglycoside phosphotransferase
GOP56_RS03855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GOP56_RS03860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GOP56_RS03865	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GOP56_RS03870	COG1335	isochorismatase
GOP56_RS03875	COG1051	belongs to the nudix hydrolase family
GOP56_RS03880	COG0346	lactoylglutathione lyase activity
GOP56_RS03885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GOP56_RS03885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GOP56_RS03895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GOP56_RS03895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GOP56_RS03900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GOP56_RS03910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS03915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOP56_RS03915	COG2070	2-Nitropropane dioxygenase
GOP56_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03920	COG4221	oxidoreductase activity
GOP56_RS03920	COG3321	synthase
GOP56_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS03925	COG3321	synthase
GOP56_RS03925	COG4221	oxidoreductase activity
GOP56_RS03930	COG4221	oxidoreductase activity
GOP56_RS03930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS03930	COG0300	oxidoreductase activity
GOP56_RS03930	COG3321	synthase
GOP56_RS03990	COG3321	synthase
GOP56_RS03990	COG4221	oxidoreductase activity
GOP56_RS03990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS03990	COG0300	oxidoreductase activity
GOP56_RS03995	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS03995	COG3321	synthase
GOP56_RS03995	COG4221	oxidoreductase activity
GOP56_RS03995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS04000	COG3321	synthase
GOP56_RS04000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS04000	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS04000	COG4221	oxidoreductase activity
GOP56_RS04005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS04010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOP56_RS04015	COG3425	synthase
GOP56_RS04020	COG1024	Enoyl-CoA hydratase
GOP56_RS04025	COG1024	Enoyl-CoA hydratase
GOP56_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS04030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS04030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS04030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS04030	COG3321	synthase
GOP56_RS04035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS04035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS04035	COG3321	synthase
GOP56_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS04035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS04040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS04040	COG3321	synthase
GOP56_RS04040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS04040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS04055	COG1396	sequence-specific DNA binding
GOP56_RS04070	COG4977	sequence-specific DNA binding
GOP56_RS04070	COG1917	Cupin 2, conserved barrel domain protein
GOP56_RS04080	COG2376	Dihydroxyacetone kinase
GOP56_RS04095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS04095	COG2207	Transcriptional regulator
GOP56_RS04100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GOP56_RS04105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS04120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOP56_RS04125	COG2271	Major facilitator Superfamily
GOP56_RS04130	COG3257	ureidoglycine aminohydrolase activity
GOP56_RS04135	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GOP56_RS04140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GOP56_RS04145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GOP56_RS04150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GOP56_RS04160	COG0549	Belongs to the carbamate kinase family
GOP56_RS04165	COG0584	glycerophosphoryl diester phosphodiesterase
GOP56_RS04170	COG0251	oxidation-reduction process
GOP56_RS04250	COG0590	tRNA wobble adenosine to inosine editing
GOP56_RS04265	COG0745	RESPONSE REGULATOR receiver
GOP56_RS04275	COG0666	response to abiotic stimulus
GOP56_RS04290	COG0745	RESPONSE REGULATOR receiver
GOP56_RS04295	COG5002	protein histidine kinase activity
GOP56_RS04295	COG3850	Histidine kinase
GOP56_RS04305	COG1136	(ABC) transporter
GOP56_RS04310	COG0577	efflux transmembrane transporter activity
GOP56_RS04325	COG0697	spore germination
GOP56_RS04330	COG1802	Transcriptional regulator
GOP56_RS04340	COG2267	carboxylic ester hydrolase activity
GOP56_RS04400	COG4319	ketosteroid isomerase
GOP56_RS04415	COG1595	DNA-templated transcription, initiation
GOP56_RS04425	COG2132	Multicopper oxidase
GOP56_RS04450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GOP56_RS04455	COG1378	Sugar-specific transcriptional regulator TrmB
GOP56_RS04470	COG1657	PFAM Prenyltransferase squalene oxidase
GOP56_RS04485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOP56_RS04500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS04540	COG1376	ErfK ybiS ycfS ynhG family protein
GOP56_RS04545	COG0596	Alpha beta hydrolase
GOP56_RS04570	COG2226	methyltransferase
GOP56_RS04575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GOP56_RS04580	COG0798	PFAM Bile acid sodium symporter
GOP56_RS04610	COG0189	ligase activity
GOP56_RS04615	COG0477	Major facilitator Superfamily
GOP56_RS04625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GOP56_RS04625	COG0723	plastoquinol--plastocyanin reductase activity
GOP56_RS04630	COG0024	Methionine aminopeptidase
GOP56_RS04660	COG1846	Transcriptional regulator
GOP56_RS04670	COG3655	Transcriptional regulator
GOP56_RS04675	COG1114	Component of the transport system for branched-chain amino acids
GOP56_RS04680	COG1132	(ABC) transporter
GOP56_RS04685	COG1132	(ABC) transporter
GOP56_RS04705	COG2130	NADP-dependent
GOP56_RS04710	COG1309	transcriptional regulator
GOP56_RS04715	COG2124	cytochrome p450
GOP56_RS04715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GOP56_RS04725	COG0640	Transcriptional regulator
GOP56_RS04730	COG3832	glyoxalase III activity
GOP56_RS04755	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS04790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS04795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS04800	COG1132	(ABC) transporter
GOP56_RS04805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GOP56_RS04820	COG3546	catalase activity
GOP56_RS04825	COG0747	negative chemotaxis
GOP56_RS04830	COG0601	transmembrane transport
GOP56_RS04835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GOP56_RS04840	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS04845	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS04915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS04925	COG0739	heme binding
GOP56_RS04925	COG0741	lytic transglycosylase activity
GOP56_RS04925	COG1196	nuclear chromosome segregation
GOP56_RS04945	COG0697	spore germination
GOP56_RS04955	COG1595	DNA-templated transcription, initiation
GOP56_RS04960	COG0385	Bile acid
GOP56_RS04965	COG1802	Transcriptional regulator
GOP56_RS04970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOP56_RS04975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOP56_RS04980	COG1780	Probably involved in ribonucleotide reductase function
GOP56_RS04985	COG4974	Belongs to the 'phage' integrase family
GOP56_RS04990	COG0488	(ABC) transporter
GOP56_RS04995	COG2217	Heavy metal translocating P-type atpase
GOP56_RS05015	COG2814	Major facilitator Superfamily
GOP56_RS05020	COG1304	FMN binding
GOP56_RS05070	COG5002	protein histidine kinase activity
GOP56_RS05075	COG0745	RESPONSE REGULATOR receiver
GOP56_RS05080	COG2132	Multicopper oxidase
GOP56_RS05085	COG0531	amino acid
GOP56_RS05115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS05150	COG2814	Major facilitator Superfamily
GOP56_RS05190	COG1473	amidohydrolase
GOP56_RS05200	COG3192	ethanolamine utilization protein
GOP56_RS05205	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GOP56_RS05215	COG4869	propanediol catabolic process
GOP56_RS05225	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS05225	COG1454	alcohol dehydrogenase
GOP56_RS05230	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GOP56_RS05235	COG4816	utilization protein
GOP56_RS05245	COG4303	Ethanolamine ammonia lyase large subunit
GOP56_RS05270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GOP56_RS05275	COG2363	Small membrane protein
GOP56_RS05280	COG0697	spore germination
GOP56_RS05330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS05335	COG0604	alcohol dehydrogenase
GOP56_RS05345	COG2427	Protein of unknown function (DUF1641)
GOP56_RS05350	COG3383	formate dehydrogenase (NAD+) activity
GOP56_RS05360	COG2814	Major facilitator Superfamily
GOP56_RS05375	COG1132	(ABC) transporter
GOP56_RS05380	COG1132	(ABC) transporter
GOP56_RS05385	COG2318	DinB family
GOP56_RS05390	COG3359	exonuclease
GOP56_RS05395	COG1205	dead DEAH box helicase
GOP56_RS05395	COG1111	helicase
GOP56_RS05400	COG1959	2 iron, 2 sulfur cluster binding
GOP56_RS05405	COG0306	phosphate transporter
GOP56_RS05410	COG1392	Phosphate transport regulator
GOP56_RS05415	COG1309	transcriptional regulator
GOP56_RS05425	COG1233	COG1233 Phytoene dehydrogenase and related
GOP56_RS05440	COG0242	peptide deformylase activity
GOP56_RS05450	COG0840	transmembrane signaling receptor activity
GOP56_RS05475	COG2909	trisaccharide binding
GOP56_RS05490	COG2329	Antibiotic biosynthesis monooxygenase
GOP56_RS05500	COG1253	flavin adenine dinucleotide binding
GOP56_RS05505	COG0789	Transcriptional regulator
GOP56_RS05510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GOP56_RS05515	COG0531	amino acid
GOP56_RS05520	COG0583	DNA-binding transcription factor activity
GOP56_RS05530	COG1876	peptidase activity
GOP56_RS05535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GOP56_RS05540	COG0537	adenosine 5'-monophosphoramidase activity
GOP56_RS05560	COG1349	DNA-binding transcription factor activity
GOP56_RS05565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GOP56_RS05590	COG1120	ATPase activity
GOP56_RS05595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS05600	COG2323	membrane
GOP56_RS05610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOP56_RS05625	COG2205	protein histidine kinase activity
GOP56_RS05635	COG0662	Cupin 2, conserved barrel domain protein
GOP56_RS05655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOP56_RS05660	COG1737	Transcriptional regulator
GOP56_RS05665	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GOP56_RS05670	COG1263	PTS System
GOP56_RS05670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GOP56_RS05670	COG2190	(PTS) system
GOP56_RS05675	COG3684	Belongs to the aldolase LacD family
GOP56_RS05690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GOP56_RS05695	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS05720	COG0697	spore germination
GOP56_RS05765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GOP56_RS05770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS05770	COG4221	oxidoreductase activity
GOP56_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS05770	COG3321	synthase
GOP56_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS05800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOP56_RS05805	COG2030	dehydratase
GOP56_RS05810	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS05825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GOP56_RS05825	COG0512	Glutamine amidotransferase of anthranilate synthase
GOP56_RS05830	COG0512	Glutamine amidotransferase of anthranilate synthase
GOP56_RS05830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GOP56_RS05835	COG2318	DinB family
GOP56_RS05840	COG1396	sequence-specific DNA binding
GOP56_RS05845	COG0006	proline dipeptidase activity
GOP56_RS05850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GOP56_RS05855	COG0045	succinate-CoA ligase (ADP-forming) activity
GOP56_RS05860	COG0508	dehydrogenase complex catalyzes the overall conversion of
GOP56_RS05865	COG0567	Dehydrogenase, E1 component
GOP56_RS05870	COG0471	metal ion transport
GOP56_RS05880	COG3192	ethanolamine utilization protein
GOP56_RS05890	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GOP56_RS05900	COG4869	propanediol catabolic process
GOP56_RS05915	COG1454	alcohol dehydrogenase
GOP56_RS05915	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS05925	COG4816	utilization protein
GOP56_RS05935	COG4303	Ethanolamine ammonia lyase large subunit
GOP56_RS05940	COG4819	ethanolamine utilization protein
GOP56_RS05980	COG0644	oxidoreductase
GOP56_RS05980	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GOP56_RS05985	COG1119	ATPase activity
GOP56_RS05990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GOP56_RS06050	COG3964	amidohydrolase
GOP56_RS06055	COG3711	transcriptional antiterminator
GOP56_RS06065	COG3973	AAA domain
GOP56_RS06085	COG0243	molybdopterin cofactor binding
GOP56_RS06095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOP56_RS06100	COG2223	nitrite transmembrane transporter activity
GOP56_RS06115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GOP56_RS06120	COG0477	Major facilitator Superfamily
GOP56_RS06125	COG3858	chitin binding
GOP56_RS06125	COG1388	LysM domain
GOP56_RS06140	COG0745	RESPONSE REGULATOR receiver
GOP56_RS06145	COG5002	protein histidine kinase activity
GOP56_RS06165	COG2861	carbohydrate metabolic process
GOP56_RS06170	COG1472	Belongs to the glycosyl hydrolase 3 family
GOP56_RS06175	COG3876	Protein conserved in bacteria
GOP56_RS06180	COG2814	Major facilitator Superfamily
GOP56_RS06185	COG0492	ferredoxin-NADP+ reductase activity
GOP56_RS06200	COG0346	lactoylglutathione lyase activity
GOP56_RS06220	COG0813	purine-nucleoside phosphorylase activity
GOP56_RS06225	COG1619	proteins homologs of microcin C7 resistance protein MccF
GOP56_RS06230	COG5002	protein histidine kinase activity
GOP56_RS06255	COG1744	ABC transporter substrate-binding protein PnrA-like
GOP56_RS06260	COG3852	Histidine kinase
GOP56_RS06265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GOP56_RS06270	COG1335	isochorismatase
GOP56_RS06290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GOP56_RS06295	COG1368	sulfuric ester hydrolase activity
GOP56_RS06300	COG2385	sporulation resulting in formation of a cellular spore
GOP56_RS06310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOP56_RS06320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GOP56_RS06325	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS06335	COG0791	NLP P60 protein
GOP56_RS06340	COG4948	Mandelate Racemase Muconate Lactonizing
GOP56_RS06345	COG1172	Belongs to the binding-protein-dependent transport system permease family
GOP56_RS06350	COG1129	ABC transporter
GOP56_RS06365	COG1122	ATPase activity
GOP56_RS06370	COG4120	Belongs to the binding-protein-dependent transport system permease family
GOP56_RS06380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOP56_RS06400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GOP56_RS06405	COG0531	amino acid
GOP56_RS06415	COG0482	sulfurtransferase activity
GOP56_RS06430	COG0519	Catalyzes the synthesis of GMP from XMP
GOP56_RS06435	COG0251	oxidation-reduction process
GOP56_RS06440	COG0446	pyridine nucleotide-disulphide oxidoreductase
GOP56_RS06445	COG1011	Hydrolase
GOP56_RS06450	COG3681	Belongs to the UPF0597 family
GOP56_RS06460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS06465	COG2169	Transcriptional regulator
GOP56_RS06475	COG1132	(ABC) transporter
GOP56_RS06480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS06485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS06495	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS06510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GOP56_RS06515	COG0488	(ABC) transporter
GOP56_RS06520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GOP56_RS06525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GOP56_RS06565	COG3093	addiction module antidote protein HigA
GOP56_RS06575	COG0673	inositol 2-dehydrogenase activity
GOP56_RS06580	COG0463	Glycosyl transferase, family 2
GOP56_RS06580	COG0457	Tetratricopeptide repeat
GOP56_RS06585	COG5337	Spore coat protein CotH
GOP56_RS06590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOP56_RS06595	COG0785	Cytochrome C biogenesis protein
GOP56_RS06600	COG3186	Phenylalanine-4-hydroxylase
GOP56_RS06620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GOP56_RS06625	COG0352	thiamine-phosphate diphosphorylase activity
GOP56_RS06630	COG2022	thiamine diphosphate biosynthetic process
GOP56_RS06640	COG0352	thiamine-phosphate diphosphorylase activity
GOP56_RS06655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GOP56_RS06660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GOP56_RS06665	COG0095	Lipoate-protein ligase
GOP56_RS06670	COG0583	DNA-binding transcription factor activity
GOP56_RS06715	COG2056	Na+-H+ antiporter family
GOP56_RS06720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GOP56_RS06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GOP56_RS06735	COG1116	anion transmembrane transporter activity
GOP56_RS06740	COG1755	Isoprenylcysteine carboxyl methyltransferase
GOP56_RS06745	COG3424	synthase
GOP56_RS06750	COG1114	Component of the transport system for branched-chain amino acids
GOP56_RS06755	COG0464	growth
GOP56_RS06770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GOP56_RS06775	COG0187	DNA topoisomerase II activity
GOP56_RS06780	COG0217	transcriptional regulatory protein
GOP56_RS06805	COG1131	(ABC) transporter
GOP56_RS06820	COG1595	DNA-templated transcription, initiation
GOP56_RS06825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GOP56_RS06830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GOP56_RS06835	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS06840	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS06845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GOP56_RS06850	COG0601	transmembrane transport
GOP56_RS06855	COG0747	negative chemotaxis
GOP56_RS06860	COG0778	Nitroreductase
GOP56_RS06865	COG2259	Doxx family
GOP56_RS06870	COG1846	Transcriptional regulator
GOP56_RS06875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS06880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS06885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS06890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS06910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS06925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS06975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GOP56_RS06990	COG2707	UPF0756 membrane protein
GOP56_RS07000	COG4848	Belongs to the UPF0354 family
GOP56_RS07020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GOP56_RS07040	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GOP56_RS07055	COG0022	dehydrogenase e1 component
GOP56_RS07085	COG0316	Belongs to the HesB IscA family
GOP56_RS07095	COG3973	AAA domain
GOP56_RS07130	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS07210	COG4224	UPF0291 protein
GOP56_RS07220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GOP56_RS07225	COG2839	Protein conserved in bacteria
GOP56_RS07240	COG0697	spore germination
GOP56_RS07245	COG1064	alcohol dehydrogenase
GOP56_RS07265	COG0697	spore germination
GOP56_RS07270	COG3800	Transcriptional regulator
GOP56_RS07270	COG1396	sequence-specific DNA binding
GOP56_RS07330	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS07335	COG5002	protein histidine kinase activity
GOP56_RS07340	COG0745	RESPONSE REGULATOR receiver
GOP56_RS07350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GOP56_RS07395	COG0456	acetyltransferase
GOP56_RS07425	COG1408	metallophosphoesterase
GOP56_RS07455	COG5002	protein histidine kinase activity
GOP56_RS07460	COG0745	RESPONSE REGULATOR receiver
GOP56_RS07475	COG1120	ATPase activity
GOP56_RS07505	COG1388	LysM domain
GOP56_RS07505	COG4641	Protein conserved in bacteria
GOP56_RS07525	COG0738	Major facilitator superfamily
GOP56_RS07535	COG0110	maltose O-acetyltransferase activity
GOP56_RS07540	COG1940	carbohydrate kinase activity
GOP56_RS07555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GOP56_RS07570	COG0747	negative chemotaxis
GOP56_RS07580	COG0488	(ABC) transporter
GOP56_RS07630	COG2318	DinB family
GOP56_RS07650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOP56_RS07665	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS07675	COG0346	lactoylglutathione lyase activity
GOP56_RS07690	COG1132	(ABC) transporter
GOP56_RS07695	COG1129	ABC transporter
GOP56_RS07730	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS07825	COG0582	viral genome integration into host DNA
GOP56_RS07830	COG0174	glutamine synthetase
GOP56_RS07835	COG0789	Transcriptional regulator
GOP56_RS07845	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GOP56_RS07855	COG0464	growth
GOP56_RS07865	COG1595	DNA-templated transcription, initiation
GOP56_RS07870	COG2207	Transcriptional regulator
GOP56_RS07870	COG1917	Cupin 2, conserved barrel domain protein
GOP56_RS07880	COG0456	acetyltransferase
GOP56_RS07885	COG1349	DNA-binding transcription factor activity
GOP56_RS07890	COG1923	regulation of RNA biosynthetic process
GOP56_RS07895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GOP56_RS07900	COG2136	Putative SAM-dependent methyltransferase
GOP56_RS07900	COG2521	methyltransferase
GOP56_RS07960	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS08010	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GOP56_RS08015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GOP56_RS08030	COG4550	Control of competence regulator ComK, YlbF/YmcA
GOP56_RS08035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOP56_RS08045	COG3620	sequence-specific DNA binding
GOP56_RS08065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GOP56_RS08075	COG2076	Multidrug Resistance protein
GOP56_RS08080	COG2076	Multidrug Resistance protein
GOP56_RS08085	COG1486	melibiose metabolic process
GOP56_RS08090	COG1447	Phosphotransferase system cellobiose-specific component IIA
GOP56_RS08110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GOP56_RS08110	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GOP56_RS08115	COG2814	Major facilitator Superfamily
GOP56_RS08125	COG1361	Conserved repeat domain
GOP56_RS08135	COG0095	Lipoate-protein ligase
GOP56_RS08140	COG0517	IMP dehydrogenase activity
GOP56_RS08150	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GOP56_RS08155	COG1234	tRNA 3'-trailer cleavage
GOP56_RS08160	COG3949	Membrane
GOP56_RS08165	COG1013	pyruvate-flavodoxin oxidoreductase activity
GOP56_RS08170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GOP56_RS08170	COG0674	pyruvate-flavodoxin oxidoreductase activity
GOP56_RS08175	COG2359	stage V sporulation protein S
GOP56_RS08180	COG1692	metallophosphoesterase
GOP56_RS08195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GOP56_RS08200	COG0513	Belongs to the DEAD box helicase family
GOP56_RS08210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GOP56_RS08215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOP56_RS08220	COG1426	Protein conserved in bacteria
GOP56_RS08235	COG0300	oxidoreductase activity
GOP56_RS08240	COG0612	Peptidase, M16
GOP56_RS08245	COG0612	Peptidase, M16
GOP56_RS08270	COG1744	ABC transporter substrate-binding protein PnrA-like
GOP56_RS08275	COG1674	ftsk spoiiie
GOP56_RS08285	COG0740	serine-type endopeptidase activity
GOP56_RS08300	COG1819	glycosyl
GOP56_RS08315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GOP56_RS08320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GOP56_RS08325	COG0527	aspartate kinase activity
GOP56_RS08330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GOP56_RS08335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GOP56_RS08340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GOP56_RS08345	COG1873	PFAM PRC-barrel domain
GOP56_RS08355	COG0612	Peptidase, M16
GOP56_RS08360	COG0726	polysaccharide deacetylase
GOP56_RS08365	COG1185	polyribonucleotide nucleotidyltransferase activity
GOP56_RS08370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GOP56_RS08375	COG0196	riboflavin kinase activity
GOP56_RS08380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GOP56_RS08385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GOP56_RS08390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GOP56_RS08395	COG1550	Protein conserved in bacteria
GOP56_RS08400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GOP56_RS08410	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GOP56_RS08415	COG0195	Participates in both transcription termination and antitermination
GOP56_RS08420	COG0779	Required for maturation of 30S ribosomal subunits
GOP56_RS08430	COG2176	DNA-directed DNA polymerase activity
GOP56_RS08435	COG0442	prolyl-tRNA aminoacylation
GOP56_RS08440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GOP56_RS08445	COG0750	zinc metalloprotease
GOP56_RS08450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GOP56_RS08455	COG4589	Belongs to the CDS family
GOP56_RS08460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GOP56_RS08465	COG0233	cytoplasmic translational termination
GOP56_RS08470	COG0528	UMP kinase activity
GOP56_RS08475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GOP56_RS08480	COG0052	Belongs to the universal ribosomal protein uS2 family
GOP56_RS08505	COG1191	sigma factor activity
GOP56_RS08515	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GOP56_RS08520	COG1776	CheC inhibitor of MCP methylation
GOP56_RS08525	COG0835	chemotaxis
GOP56_RS08530	COG2198	Histidine kinase
GOP56_RS08530	COG0643	Histidine kinase
GOP56_RS08535	COG2201	protein-glutamate methylesterase activity
GOP56_RS08540	COG0455	bacterial-type flagellum organization
GOP56_RS08545	COG1419	protein localization to endoplasmic reticulum
GOP56_RS08550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GOP56_RS08555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GOP56_RS08560	COG1684	flagellar biosynthetic protein fliR
GOP56_RS08565	COG1987	bacterial-type flagellum assembly
GOP56_RS08570	COG1338	Plays a role in the flagellum-specific transport system
GOP56_RS08575	COG3190	flagellar
GOP56_RS08580	COG2201	protein-glutamate methylesterase activity
GOP56_RS08585	COG1776	CheC inhibitor of MCP methylation
GOP56_RS08585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GOP56_RS08590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GOP56_RS08595	COG1580	Controls the rotational direction of flagella during chemotaxis
GOP56_RS08600	COG1582	Flagellar protein (FlbD)
GOP56_RS08605	COG4786	Flagellar basal body rod
GOP56_RS08630	COG1157	protein secretion by the type III secretion system
GOP56_RS08640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GOP56_RS08645	COG1766	The M ring may be actively involved in energy transduction
GOP56_RS08650	COG1677	Flagellar hook-basal body complex protein FliE
GOP56_RS08655	COG1558	bacterial-type flagellum-dependent cell motility
GOP56_RS08660	COG1815	bacterial-type flagellum-dependent cell motility
GOP56_RS08665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GOP56_RS08670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GOP56_RS08675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GOP56_RS08680	COG4974	Belongs to the 'phage' integrase family
GOP56_RS08685	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GOP56_RS08690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GOP56_RS08695	COG0758	DNA mediated transformation
GOP56_RS08700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GOP56_RS08705	COG0045	succinate-CoA ligase (ADP-forming) activity
GOP56_RS08725	COG0488	(ABC) transporter
GOP56_RS08735	COG2002	toxin-antitoxin pair type II binding
GOP56_RS08740	COG0792	nuclease activity
GOP56_RS08745	COG2257	FlhB HrpN YscU SpaS Family
GOP56_RS08755	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GOP56_RS08770	COG0335	large ribosomal subunit rRNA binding
GOP56_RS08775	COG0336	Belongs to the RNA methyltransferase TrmD family
GOP56_RS08780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GOP56_RS08790	COG1837	Belongs to the UPF0109 family
GOP56_RS08795	COG0228	four-way junction DNA binding
GOP56_RS08800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GOP56_RS08805	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GOP56_RS08810	COG0552	protein localization to endoplasmic reticulum
GOP56_RS08815	COG1196	nuclear chromosome segregation
GOP56_RS08820	COG0571	ribonuclease III activity
GOP56_RS08825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOP56_RS08830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GOP56_RS08850	COG0416	fatty acid biosynthetic process
GOP56_RS08855	COG1349	DNA-binding transcription factor activity
GOP56_RS08860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GOP56_RS08870	COG1323	Belongs to the UPF0348 family
GOP56_RS08875	COG3480	Lon protease (S16) C-terminal proteolytic domain
GOP56_RS08880	COG1752	Esterase of the alpha-beta hydrolase superfamily
GOP56_RS08885	COG3314	Sporulation integral membrane protein YlbJ
GOP56_RS08890	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GOP56_RS08895	COG0742	ribosomal rna small subunit methyltransferase
GOP56_RS08900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GOP56_RS08905	COG0386	Belongs to the glutathione peroxidase family
GOP56_RS08910	COG0789	Transcriptional regulator
GOP56_RS08925	COG3285	dna ligase
GOP56_RS08925	COG1793	dna ligase
GOP56_RS08940	COG0306	phosphate transporter
GOP56_RS08950	COG3706	GGDEF domain
GOP56_RS08955	COG0346	lactoylglutathione lyase activity
GOP56_RS08960	COG1846	Transcriptional regulator
GOP56_RS09005	COG2357	RelA SpoT domain protein
GOP56_RS09025	COG1846	Transcriptional regulator
GOP56_RS09040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GOP56_RS09050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GOP56_RS09055	COG1760	l-serine dehydratase
GOP56_RS09060	COG1760	l-serine dehydratase
GOP56_RS09075	COG0697	spore germination
GOP56_RS09085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GOP56_RS09085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GOP56_RS09100	COG1307	EDD domain protein, DegV family
GOP56_RS09105	COG1461	Dihydroxyacetone kinase
GOP56_RS09110	COG1302	Protein conserved in bacteria
GOP56_RS09115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GOP56_RS09125	COG1564	THIamine pyrophosphokinase
GOP56_RS09130	COG1126	abc transporter atp-binding protein
GOP56_RS09135	COG0765	amino acid transport
GOP56_RS09140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GOP56_RS09145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GOP56_RS09150	COG1162	GTPase activity
GOP56_RS09155	COG0515	serine threonine protein kinase
GOP56_RS09155	COG2815	serine threonine protein kinase
GOP56_RS09160	COG0631	protein serine/threonine phosphatase activity
GOP56_RS09165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GOP56_RS09170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GOP56_RS09170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GOP56_RS09175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GOP56_RS09180	COG0242	peptide deformylase activity
GOP56_RS09185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GOP56_RS09190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GOP56_RS09205	COG1758	RNA polymerase activity
GOP56_RS09210	COG0194	GDP metabolic process
GOP56_RS09215	COG2052	Domain of unknown function (DUF370)
GOP56_RS09220	COG1561	YicC-like family, N-terminal region
GOP56_RS09250	COG1547	Domain of unknown function (DUF309)
GOP56_RS09265	COG4846	Membrane protein involved in cytochrome C biogenesis
GOP56_RS09270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GOP56_RS09275	COG2076	Multidrug Resistance protein
GOP56_RS09295	COG0284	orotidine-5'-phosphate decarboxylase activity
GOP56_RS09300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GOP56_RS09305	COG0505	Belongs to the CarA family
GOP56_RS09310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GOP56_RS09315	COG0540	Belongs to the ATCase OTCase family
GOP56_RS09325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GOP56_RS09330	COG0564	pseudouridine synthase activity
GOP56_RS09335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GOP56_RS09345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GOP56_RS09355	COG0833	amino acid
GOP56_RS09360	COG2311	Membrane
GOP56_RS09370	COG0492	ferredoxin-NADP+ reductase activity
GOP56_RS09375	COG0494	nUDIX hydrolase
GOP56_RS09385	COG1228	amidohydrolase
GOP56_RS09395	COG4166	transmembrane transport
GOP56_RS09400	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS09405	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS09410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GOP56_RS09415	COG0601	transmembrane transport
GOP56_RS09420	COG2814	Major facilitator Superfamily
GOP56_RS09425	COG4948	Mandelate Racemase Muconate Lactonizing
GOP56_RS09430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GOP56_RS09435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GOP56_RS09440	COG3599	regulation of cell shape
GOP56_RS09445	COG2302	S4 RNA-binding domain
GOP56_RS09450	COG0762	integral membrane protein
GOP56_RS09455	COG1799	cell septum assembly
GOP56_RS09460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GOP56_RS09470	COG1873	PFAM PRC-barrel domain
GOP56_RS09475	COG1191	sigma factor activity
GOP56_RS09480	COG1191	sigma factor activity
GOP56_RS09490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GOP56_RS09495	COG0849	cell division
GOP56_RS09500	COG3856	small basic protein
GOP56_RS09515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GOP56_RS09520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GOP56_RS09535	COG0772	Belongs to the SEDS family
GOP56_RS09540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GOP56_RS09545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GOP56_RS09555	COG0768	penicillin binding
GOP56_RS09570	COG0275	rRNA processing
GOP56_RS09575	COG2001	Belongs to the MraZ family
GOP56_RS09580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GOP56_RS09595	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GOP56_RS09610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GOP56_RS09620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GOP56_RS09625	COG1024	Enoyl-CoA hydratase
GOP56_RS09630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOP56_RS09635	COG0511	ligase activity, forming carbon-carbon bonds
GOP56_RS09640	COG0439	Biotin carboxylase
GOP56_RS09645	COG0454	-acetyltransferase
GOP56_RS09660	COG1393	Belongs to the ArsC family
GOP56_RS09690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS09710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GOP56_RS09720	COG0667	Aldo Keto reductase
GOP56_RS09765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GOP56_RS09790	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GOP56_RS09820	COG1982	Orn Lys Arg decarboxylase major
GOP56_RS09860	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS09875	COG1473	amidohydrolase
GOP56_RS09880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOP56_RS09885	COG2171	N-acyltransferase activity
GOP56_RS09905	COG1126	abc transporter atp-binding protein
GOP56_RS09910	COG0765	amino acid transport
GOP56_RS09915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GOP56_RS09925	COG0393	Putative heavy-metal-binding
GOP56_RS09950	COG0463	Glycosyl transferase, family 2
GOP56_RS09950	COG0457	Tetratricopeptide repeat
GOP56_RS09960	COG1091	dTDP-4-dehydrorhamnose reductase activity
GOP56_RS09970	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GOP56_RS09975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GOP56_RS09980	COG0463	Glycosyl transferase, family 2
GOP56_RS10055	COG2252	PERMEase
GOP56_RS10060	COG0778	Nitroreductase
GOP56_RS10070	COG4085	toxin activity
GOP56_RS10070	COG0737	Belongs to the 5'-nucleotidase family
GOP56_RS10070	COG1525	nuclease
GOP56_RS10100	COG2017	converts alpha-aldose to the beta-anomer
GOP56_RS10140	COG2971	BadF BadG BcrA BcrD
GOP56_RS10145	COG0165	Argininosuccinate lyase
GOP56_RS10150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GOP56_RS10160	COG3842	ATPase activity
GOP56_RS10165	COG1840	ABC-type Fe3 transport system, periplasmic component
GOP56_RS10170	COG2207	Transcriptional regulator
GOP56_RS10190	COG2378	regulation of single-species biofilm formation
GOP56_RS10195	COG3708	Transcriptional regulator
GOP56_RS10205	COG1378	Sugar-specific transcriptional regulator TrmB
GOP56_RS10210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GOP56_RS10210	COG2755	lipolytic protein G-D-S-L family
GOP56_RS10360	COG1396	sequence-specific DNA binding
GOP56_RS10365	COG0577	efflux transmembrane transporter activity
GOP56_RS10370	COG1136	(ABC) transporter
GOP56_RS10375	COG2205	protein histidine kinase activity
GOP56_RS10380	COG0745	RESPONSE REGULATOR receiver
GOP56_RS10410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GOP56_RS10420	COG1846	Transcriptional regulator
GOP56_RS10425	COG4585	Histidine kinase
GOP56_RS10430	COG2197	response regulator
GOP56_RS10435	COG2814	Major facilitator Superfamily
GOP56_RS10440	COG0583	DNA-binding transcription factor activity
GOP56_RS10445	COG4221	oxidoreductase activity
GOP56_RS10450	COG0300	oxidoreductase activity
GOP56_RS10455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GOP56_RS10460	COG4122	O-methyltransferase activity
GOP56_RS10490	COG0436	Aminotransferase
GOP56_RS10500	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS10505	COG1733	regulation of RNA biosynthetic process
GOP56_RS10530	COG1227	inorganic diphosphatase activity
GOP56_RS10535	COG2843	Capsule synthesis protein
GOP56_RS10540	COG2814	Major facilitator Superfamily
GOP56_RS10545	COG1473	amidohydrolase
GOP56_RS10555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GOP56_RS10565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GOP56_RS10575	COG0656	L-ascorbic acid biosynthetic process
GOP56_RS10580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOP56_RS10585	COG0384	phenazine biosynthesis protein PhzF
GOP56_RS10590	COG1408	metallophosphoesterase
GOP56_RS10595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GOP56_RS10600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GOP56_RS10605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GOP56_RS10610	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GOP56_RS10645	COG0488	(ABC) transporter
GOP56_RS10660	COG2819	hydrolase of the alpha beta superfamily
GOP56_RS10665	COG2207	Transcriptional regulator
GOP56_RS10665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS10690	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GOP56_RS10700	COG0714	Associated with various cellular activities
GOP56_RS10725	COG2226	methyltransferase
GOP56_RS10725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS10725	COG3433	isochorismatase activity
GOP56_RS10730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GOP56_RS10730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS10730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS10730	COG3321	synthase
GOP56_RS10730	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS10740	COG3433	isochorismatase activity
GOP56_RS10740	COG2226	methyltransferase
GOP56_RS10740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS10745	COG1021	2,3-dihydroxybenzoate-AMP ligase
GOP56_RS10765	COG1129	ABC transporter
GOP56_RS10775	COG1132	(ABC) transporter
GOP56_RS10780	COG0840	transmembrane signaling receptor activity
GOP56_RS10795	COG2962	Rard protein
GOP56_RS10800	COG2140	Oxalate decarboxylase
GOP56_RS10805	COG3186	Phenylalanine-4-hydroxylase
GOP56_RS10815	COG0658	competence protein
GOP56_RS10815	COG2333	competence protein COMEC
GOP56_RS10895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GOP56_RS10900	COG2378	regulation of single-species biofilm formation
GOP56_RS10910	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS10955	COG0456	acetyltransferase
GOP56_RS10960	COG1388	LysM domain
GOP56_RS10975	COG0582	viral genome integration into host DNA
GOP56_RS11040	COG3299	homolog of phage Mu protein gp47
GOP56_RS11045	COG3628	GPW Gp25 family protein
GOP56_RS11190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GOP56_RS11195	COG0756	dUTP diphosphatase activity
GOP56_RS11210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GOP56_RS11230	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GOP56_RS11260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOP56_RS11260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOP56_RS11410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GOP56_RS11425	COG0840	transmembrane signaling receptor activity
GOP56_RS11440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GOP56_RS11445	COG2382	esterase
GOP56_RS11450	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GOP56_RS11470	COG1253	flavin adenine dinucleotide binding
GOP56_RS11475	COG0210	DNA helicase
GOP56_RS11500	COG0861	Integral membrane protein TerC family
GOP56_RS11515	COG0835	chemotaxis
GOP56_RS11525	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GOP56_RS11540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GOP56_RS11545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GOP56_RS11550	COG1404	Belongs to the peptidase S8 family
GOP56_RS11555	COG1253	flavin adenine dinucleotide binding
GOP56_RS11565	COG1595	DNA-templated transcription, initiation
GOP56_RS11580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GOP56_RS11585	COG1131	(ABC) transporter
GOP56_RS11590	COG2755	lipolytic protein G-D-S-L family
GOP56_RS11595	COG2211	Major facilitator Superfamily
GOP56_RS11600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GOP56_RS11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS11620	COG1285	pathogenesis
GOP56_RS11630	COG2971	BadF BadG BcrA BcrD
GOP56_RS11640	COG1447	Phosphotransferase system cellobiose-specific component IIA
GOP56_RS11650	COG1486	melibiose metabolic process
GOP56_RS11660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GOP56_RS11685	COG0739	heme binding
GOP56_RS11690	COG0745	RESPONSE REGULATOR receiver
GOP56_RS11695	COG2205	protein histidine kinase activity
GOP56_RS11700	COG1902	pentaerythritol trinitrate reductase activity
GOP56_RS11700	COG0446	pyridine nucleotide-disulphide oxidoreductase
GOP56_RS11705	COG2084	Dehydrogenase
GOP56_RS11720	COG1316	TRANSCRIPTIONal
GOP56_RS11725	COG0653	protein targeting
GOP56_RS11740	COG0671	phosphoesterase, PA-phosphatase related
GOP56_RS11745	COG1929	Belongs to the glycerate kinase type-1 family
GOP56_RS11750	COG2610	gluconate transmembrane transporter activity
GOP56_RS11755	COG3835	regulator
GOP56_RS11765	COG1910	domain protein
GOP56_RS11770	COG0725	ABC transporter, periplasmic molybdate-binding protein
GOP56_RS11775	COG4149	molybdate abc transporter
GOP56_RS11785	COG3481	metal-dependent phosphohydrolase, HD sub domain
GOP56_RS11795	COG0586	Pfam SNARE associated Golgi protein
GOP56_RS11805	COG1983	PspC domain protein
GOP56_RS11815	COG1510	regulation of RNA biosynthetic process
GOP56_RS11820	COG4175	Glycine betaine
GOP56_RS11820	COG0517	IMP dehydrogenase activity
GOP56_RS11830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GOP56_RS11840	COG0179	Fumarylacetoacetate (FAA) hydrolase
GOP56_RS11850	COG0564	pseudouridine synthase activity
GOP56_RS11860	COG0601	transmembrane transport
GOP56_RS11870	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS11875	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS11880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GOP56_RS11895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GOP56_RS11900	COG3874	Sporulation protein YtfJ
GOP56_RS11910	COG3584	3D domain protein
GOP56_RS11910	COG1388	LysM domain
GOP56_RS11925	COG0861	Integral membrane protein TerC family
GOP56_RS11930	COG5002	protein histidine kinase activity
GOP56_RS12025	COG0301	tRNA thio-modification
GOP56_RS12030	COG1104	cysteine desulfurase activity
GOP56_RS12035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GOP56_RS12045	COG4709	membrane
GOP56_RS12050	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GOP56_RS12080	COG4221	oxidoreductase activity
GOP56_RS12090	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GOP56_RS12100	COG4326	sporulation control protein
GOP56_RS12125	COG1363	Peptidase, m42
GOP56_RS12130	COG2081	HI0933 family
GOP56_RS12140	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GOP56_RS12145	COG1309	transcriptional regulator
GOP56_RS12150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GOP56_RS12155	COG2203	Gaf domain
GOP56_RS12155	COG2199	diguanylate cyclase activity
GOP56_RS12160	COG0406	alpha-ribazole phosphatase activity
GOP56_RS12170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GOP56_RS12175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOP56_RS12180	COG0454	-acetyltransferase
GOP56_RS12185	COG0517	IMP dehydrogenase activity
GOP56_RS12190	COG0123	including yeast histone deacetylase and acetoin utilization protein
GOP56_RS12195	COG2514	catechol 2,3-dioxygenase activity
GOP56_RS12205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GOP56_RS12210	COG1609	Transcriptional regulator
GOP56_RS12215	COG1605	Chorismate mutase
GOP56_RS12215	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GOP56_RS12220	COG0849	cell division
GOP56_RS12225	COG3118	belongs to the thioredoxin family
GOP56_RS12240	COG2309	aminopeptidase activity
GOP56_RS12250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOP56_RS12255	COG2059	Chromate
GOP56_RS12260	COG2059	Chromate
GOP56_RS12295	COG0436	Aminotransferase
GOP56_RS12305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GOP56_RS12320	COG1595	DNA-templated transcription, initiation
GOP56_RS12330	COG0315	cyclic pyranopterin monophosphate synthase activity
GOP56_RS12335	COG0314	molybdopterin synthase activity
GOP56_RS12340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GOP56_RS12345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GOP56_RS12365	COG1674	ftsk spoiiie
GOP56_RS12380	COG0528	UMP kinase activity
GOP56_RS12395	COG0697	spore germination
GOP56_RS12400	COG0681	Belongs to the peptidase S26 family
GOP56_RS12405	COG0129	dihydroxy-acid dehydratase activity
GOP56_RS12410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GOP56_RS12425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOP56_RS12475	COG1120	ATPase activity
GOP56_RS12480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GOP56_RS12500	COG0483	inositol monophosphate 1-phosphatase activity
GOP56_RS12515	COG1966	Carbon starvation protein
GOP56_RS12520	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GOP56_RS12525	COG2226	methyltransferase
GOP56_RS12535	COG2814	Major facilitator Superfamily
GOP56_RS12545	COG1566	PFAM secretion protein HlyD family protein
GOP56_RS12550	COG1846	Transcriptional regulator
GOP56_RS12565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GOP56_RS12570	COG2357	RelA SpoT domain protein
GOP56_RS12575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GOP56_RS12575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GOP56_RS12580	COG1309	transcriptional regulator
GOP56_RS12585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GOP56_RS12590	COG0826	peptidase U32
GOP56_RS12595	COG4840	Belongs to the UPF0435 family
GOP56_RS12600	COG0823	Involved in the tonB-independent uptake of proteins
GOP56_RS12600	COG1506	peptidase
GOP56_RS12600	COG4946	Tricorn protease homolog
GOP56_RS12605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOP56_RS12615	COG1473	amidohydrolase
GOP56_RS12620	COG1278	Cold shock
GOP56_RS12625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GOP56_RS12630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GOP56_RS12665	COG1214	PFAM Peptidase M22, glycoprotease
GOP56_RS12665	COG0456	acetyltransferase
GOP56_RS12670	COG1309	transcriptional regulator
GOP56_RS12675	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS12690	COG5002	protein histidine kinase activity
GOP56_RS12695	COG4191	Histidine kinase
GOP56_RS12715	COG0726	polysaccharide deacetylase
GOP56_RS12720	COG4129	membrane
GOP56_RS12730	COG1609	Transcriptional regulator
GOP56_RS12735	COG0561	phosphatase activity
GOP56_RS12745	COG1349	DNA-binding transcription factor activity
GOP56_RS12755	COG2313	pseudouridylate synthase activity
GOP56_RS12760	COG1288	antiporter activity
GOP56_RS12775	COG1263	PTS System
GOP56_RS12775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GOP56_RS12780	COG0363	glucosamine-6-phosphate deaminase activity
GOP56_RS12790	COG3711	transcriptional antiterminator
GOP56_RS12805	COG1879	ABC-type sugar transport system periplasmic component
GOP56_RS12810	COG1172	Belongs to the binding-protein-dependent transport system permease family
GOP56_RS12815	COG1129	ABC transporter
GOP56_RS12820	COG1869	D-ribose catabolic process
GOP56_RS12825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GOP56_RS12830	COG1609	Transcriptional regulator
GOP56_RS12835	COG1307	EDD domain protein, DegV family
GOP56_RS12840	COG1228	amidohydrolase
GOP56_RS12845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GOP56_RS12850	COG2207	Transcriptional regulator
GOP56_RS12855	COG1027	Aspartate ammonia-lyase
GOP56_RS12865	COG1072	(Pantothenic acid kinase))
GOP56_RS12875	COG4533	DNA binding
GOP56_RS12880	COG2814	Major facilitator Superfamily
GOP56_RS12880	COG0477	Major facilitator Superfamily
GOP56_RS12885	COG2814	Major facilitator Superfamily
GOP56_RS12890	COG2843	Capsule synthesis protein
GOP56_RS12925	COG3620	sequence-specific DNA binding
GOP56_RS12955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GOP56_RS12960	COG1832	CoA-binding protein
GOP56_RS12965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GOP56_RS12980	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GOP56_RS12985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS12990	COG3584	3D domain protein
GOP56_RS13015	COG1252	NADH dehydrogenase
GOP56_RS13030	COG1842	Phage shock protein A
GOP56_RS13055	COG0316	Belongs to the HesB IscA family
GOP56_RS13065	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GOP56_RS13070	COG4844	belongs to the
GOP56_RS13075	COG1252	NADH dehydrogenase
GOP56_RS13095	COG4837	Protein of unknown function (DUF1462)
GOP56_RS13100	COG0626	cystathionine gamma-synthase activity
GOP56_RS13105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GOP56_RS13110	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GOP56_RS13120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GOP56_RS13130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GOP56_RS13135	COG0647	UMP catabolic process
GOP56_RS13145	COG2445	Protein of unknown function DUF86
GOP56_RS13150	COG1494	fructose-1,6-bisphosphatase
GOP56_RS13165	COG4470	Protein conserved in bacteria
GOP56_RS13175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GOP56_RS13185	COG0420	3'-5' exonuclease activity
GOP56_RS13195	COG0739	heme binding
GOP56_RS13200	COG0598	Magnesium transport protein CorA
GOP56_RS13210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GOP56_RS13220	COG3377	Domain of unknown function (DUF1805)
GOP56_RS13225	COG0730	response to heat
GOP56_RS13230	COG1801	Protein of unknown function DUF72
GOP56_RS13255	COG2608	mercury ion transmembrane transporter activity
GOP56_RS13260	COG2268	Band 7 protein
GOP56_RS13325	COG0719	Fe-S assembly protein
GOP56_RS13330	COG0822	iron-sulfur transferase activity
GOP56_RS13335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GOP56_RS13340	COG0719	Fe-S assembly protein
GOP56_RS13345	COG0396	ATPase activity
GOP56_RS13355	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GOP56_RS13375	COG5002	protein histidine kinase activity
GOP56_RS13380	COG0745	RESPONSE REGULATOR receiver
GOP56_RS13390	COG0509	glycine decarboxylation via glycine cleavage system
GOP56_RS13395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GOP56_RS13400	COG0450	alkyl hydroperoxide reductase
GOP56_RS13405	COG1393	Belongs to the ArsC family
GOP56_RS13440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GOP56_RS13455	COG2217	Heavy metal translocating P-type atpase
GOP56_RS13460	COG0477	Major facilitator Superfamily
GOP56_RS13465	COG1132	(ABC) transporter
GOP56_RS13470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOP56_RS13475	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GOP56_RS13485	COG1850	ribulose-bisphosphate carboxylase activity
GOP56_RS13490	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GOP56_RS13495	COG0235	Class ii aldolase
GOP56_RS13500	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GOP56_RS13515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GOP56_RS13515	COG2190	(PTS) system
GOP56_RS13515	COG1263	PTS System
GOP56_RS13525	COG1609	Transcriptional regulator
GOP56_RS13530	COG1960	acyl-CoA dehydrogenase activity
GOP56_RS13535	COG0183	Belongs to the thiolase family
GOP56_RS13540	COG1024	Enoyl-CoA hydratase
GOP56_RS13540	COG1250	3-hydroxyacyl-CoA dehydrogenase
GOP56_RS13555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GOP56_RS13560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GOP56_RS13580	COG5577	PFAM Coat F domain
GOP56_RS13595	COG1309	transcriptional regulator
GOP56_RS13605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GOP56_RS13610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GOP56_RS13615	COG0167	dihydroorotate dehydrogenase activity
GOP56_RS13620	COG0686	Belongs to the AlaDH PNT family
GOP56_RS13625	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GOP56_RS13625	COG2508	Transcriptional regulator
GOP56_RS13630	COG2814	Major facilitator Superfamily
GOP56_RS13640	COG0535	radical SAM domain protein
GOP56_RS13645	COG1506	peptidase
GOP56_RS13650	COG1098	S1 RNA binding domain
GOP56_RS13655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GOP56_RS13665	COG0561	phosphatase activity
GOP56_RS13670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GOP56_RS13675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GOP56_RS13685	COG0788	formyltetrahydrofolate deformylase activity
GOP56_RS13700	COG1074	ATP-dependent DNA helicase activity
GOP56_RS13705	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GOP56_RS13710	COG0419	ATPase involved in DNA repair
GOP56_RS13715	COG0420	3'-5' exonuclease activity
GOP56_RS13725	COG1612	heme a metabolic process
GOP56_RS13735	COG0730	response to heat
GOP56_RS13755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GOP56_RS13755	COG1116	anion transmembrane transporter activity
GOP56_RS13770	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS13770	COG1454	alcohol dehydrogenase
GOP56_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS13785	COG2610	gluconate transmembrane transporter activity
GOP56_RS13790	COG3829	transcription factor binding
GOP56_RS13790	COG3290	protein histidine kinase activity
GOP56_RS13795	COG2340	Cysteine-rich secretory protein family
GOP56_RS13810	COG1940	carbohydrate kinase activity
GOP56_RS13815	COG2076	Multidrug Resistance protein
GOP56_RS13825	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GOP56_RS13840	COG0716	FMN binding
GOP56_RS13850	COG2814	Major facilitator Superfamily
GOP56_RS13855	COG1566	PFAM secretion protein HlyD family protein
GOP56_RS13885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS13890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS13895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS13900	COG2770	Histidine kinase
GOP56_RS13900	COG2205	protein histidine kinase activity
GOP56_RS13905	COG0745	RESPONSE REGULATOR receiver
GOP56_RS13910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GOP56_RS13915	COG1086	Polysaccharide biosynthesis protein
GOP56_RS13925	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS13930	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS13935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GOP56_RS13940	COG0601	transmembrane transport
GOP56_RS13950	COG2205	protein histidine kinase activity
GOP56_RS13955	COG0745	RESPONSE REGULATOR receiver
GOP56_RS13965	COG4895	conserved protein (DUF2196)
GOP56_RS13985	COG0384	phenazine biosynthesis protein PhzF
GOP56_RS13995	COG5566	PFAM Mor transcription activator
GOP56_RS14040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GOP56_RS14045	COG0557	exoribonuclease II activity
GOP56_RS14050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GOP56_RS14055	COG2010	Cytochrome c
GOP56_RS14060	COG0148	phosphopyruvate hydratase activity
GOP56_RS14070	COG0149	triose-phosphate isomerase activity
GOP56_RS14075	COG0126	phosphoglycerate kinase activity
GOP56_RS14080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GOP56_RS14095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GOP56_RS14120	COG1595	DNA-templated transcription, initiation
GOP56_RS14135	COG0740	serine-type endopeptidase activity
GOP56_RS14145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS14150	COG1481	regulation of sporulation
GOP56_RS14155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GOP56_RS14160	COG1660	Displays ATPase and GTPase activities
GOP56_RS14165	COG0492	ferredoxin-NADP+ reductase activity
GOP56_RS14215	COG0140	phosphoribosyl-ATP diphosphatase activity
GOP56_RS14215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GOP56_RS14220	COG0107	imidazoleglycerol-phosphate synthase activity
GOP56_RS14225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GOP56_RS14230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GOP56_RS14235	COG0131	Imidazoleglycerol-phosphate dehydratase
GOP56_RS14240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GOP56_RS14245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GOP56_RS14250	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GOP56_RS14255	COG0110	maltose O-acetyltransferase activity
GOP56_RS14260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GOP56_RS14265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GOP56_RS14270	COG0556	nucleotide-excision repair
GOP56_RS14275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GOP56_RS14280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOP56_RS14285	COG0793	Belongs to the peptidase S41A family
GOP56_RS14285	COG3409	Peptidoglycan-binding domain 1 protein
GOP56_RS14290	COG0739	heme binding
GOP56_RS14295	COG2177	Part of the ABC transporter FtsEX involved in
GOP56_RS14300	COG2884	Cell division ATP-binding protein ftsE
GOP56_RS14305	COG0165	Argininosuccinate lyase
GOP56_RS14310	COG0137	argininosuccinate synthase activity
GOP56_RS14315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GOP56_RS14320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GOP56_RS14325	COG0505	Belongs to the CarA family
GOP56_RS14330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOP56_RS14335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GOP56_RS14340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GOP56_RS14345	COG2010	Cytochrome c
GOP56_RS14375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOP56_RS14380	COG0653	protein targeting
GOP56_RS14385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GOP56_RS14390	COG1278	Cold shock
GOP56_RS14400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GOP56_RS14420	COG1516	flagellar protein fliS
GOP56_RS14425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GOP56_RS14430	COG1334	flagellar protein FlaG
GOP56_RS14445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GOP56_RS14450	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GOP56_RS14460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GOP56_RS14465	COG1256	bacterial-type flagellum assembly
GOP56_RS14465	COG4786	Flagellar basal body rod
GOP56_RS14485	COG0024	Methionine aminopeptidase
GOP56_RS14495	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GOP56_RS14515	COG1649	PFAM Uncharacterised BCR, COG1649
GOP56_RS14515	COG0726	polysaccharide deacetylase
GOP56_RS14520	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GOP56_RS14550	COG1309	transcriptional regulator
GOP56_RS14555	COG0534	Mate efflux family protein
GOP56_RS14560	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS14565	COG2373	Large extracellular alpha-helical protein
GOP56_RS14575	COG1739	Uncharacterized protein family UPF0029
GOP56_RS14580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GOP56_RS14595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GOP56_RS14610	COG4786	Flagellar basal body rod
GOP56_RS14620	COG1609	Transcriptional regulator
GOP56_RS14625	COG0739	heme binding
GOP56_RS14630	COG2385	sporulation resulting in formation of a cellular spore
GOP56_RS14635	COG0436	Aminotransferase
GOP56_RS14640	COG1522	sequence-specific DNA binding
GOP56_RS14645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GOP56_RS14655	COG4836	Membrane
GOP56_RS14660	COG1007	ATP synthesis coupled electron transport
GOP56_RS14665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOP56_RS14670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GOP56_RS14675	COG0713	ATP synthesis coupled electron transport
GOP56_RS14685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOP56_RS14690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GOP56_RS14695	COG0649	NAD binding
GOP56_RS14700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOP56_RS14705	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOP56_RS14710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GOP56_RS14715	COG1404	Belongs to the peptidase S8 family
GOP56_RS14725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GOP56_RS14730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GOP56_RS14735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GOP56_RS14740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GOP56_RS14745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GOP56_RS14760	COG0356	it plays a direct role in the translocation of protons across the membrane
GOP56_RS14780	COG1361	Conserved repeat domain
GOP56_RS14785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GOP56_RS14790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GOP56_RS14800	COG4475	Protein of unknown function (DUF436)
GOP56_RS14805	COG0698	ribose 5-phosphate isomerase
GOP56_RS14815	COG1971	Probably functions as a manganese efflux pump
GOP56_RS14820	COG0009	L-threonylcarbamoyladenylate synthase
GOP56_RS14835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GOP56_RS14850	COG0254	rRNA binding
GOP56_RS14860	COG1388	LysM domain
GOP56_RS14860	COG3584	3D domain protein
GOP56_RS14865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GOP56_RS14870	COG1494	fructose-1,6-bisphosphatase
GOP56_RS14875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GOP56_RS14880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GOP56_RS14885	COG0191	fructose-bisphosphate aldolase activity
GOP56_RS14890	COG2204	response regulator
GOP56_RS14895	COG0504	CTP synthase activity
GOP56_RS14900	COG3343	RNA polymerase activity
GOP56_RS14905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GOP56_RS14905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GOP56_RS14905	COG1703	isobutyryl-CoA mutase activity
GOP56_RS14920	COG1960	acyl-CoA dehydrogenase activity
GOP56_RS14925	COG1960	acyl-CoA dehydrogenase activity
GOP56_RS14930	COG1250	3-hydroxyacyl-CoA dehydrogenase
GOP56_RS14935	COG0183	Belongs to the thiolase family
GOP56_RS14940	COG2181	nitrate reductase activity
GOP56_RS14940	COG0247	lactate metabolic process
GOP56_RS14945	COG1509	lysine 2,3-aminomutase activity
GOP56_RS14950	COG3829	transcription factor binding
GOP56_RS14970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GOP56_RS14975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOP56_RS14990	COG3465	dGTPase activity
GOP56_RS14995	COG1078	dGTPase activity
GOP56_RS15000	COG0564	pseudouridine synthase activity
GOP56_RS15005	COG2309	aminopeptidase activity
GOP56_RS15020	COG3693	PFAM glycoside hydrolase, family 10
GOP56_RS15025	COG0116	Belongs to the methyltransferase superfamily
GOP56_RS15030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GOP56_RS15035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS15040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS15045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS15065	COG1177	transmembrane transport
GOP56_RS15070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GOP56_RS15085	COG0527	aspartate kinase activity
GOP56_RS15090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOP56_RS15100	COG0753	catalase activity
GOP56_RS15115	COG1132	(ABC) transporter
GOP56_RS15120	COG1132	(ABC) transporter
GOP56_RS15125	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS15135	COG1297	OPT oligopeptide transporter protein
GOP56_RS15140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GOP56_RS15145	COG0303	'Molybdopterin
GOP56_RS15150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GOP56_RS15160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GOP56_RS15185	COG1131	(ABC) transporter
GOP56_RS15200	COG0084	hydrolase, TatD family'
GOP56_RS15205	COG1115	amino acid carrier protein
GOP56_RS15220	COG0446	pyridine nucleotide-disulphide oxidoreductase
GOP56_RS15235	COG0531	amino acid
GOP56_RS15240	COG0584	glycerophosphoryl diester phosphodiesterase
GOP56_RS15245	COG1653	transport
GOP56_RS15250	COG0395	ABC-type sugar transport system, permease component
GOP56_RS15255	COG1175	transmembrane transport
GOP56_RS15260	COG3842	ATPase activity
GOP56_RS15275	COG0840	transmembrane signaling receptor activity
GOP56_RS15305	COG2205	protein histidine kinase activity
GOP56_RS15310	COG0488	(ABC) transporter
GOP56_RS15315	COG0277	FAD linked oxidase domain protein
GOP56_RS15320	COG1595	DNA-templated transcription, initiation
GOP56_RS15335	COG0737	Belongs to the 5'-nucleotidase family
GOP56_RS15340	COG0514	ATP-dependent DNA helicase (RecQ)
GOP56_RS15345	COG2208	phosphoserine phosphatase activity
GOP56_RS15355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GOP56_RS15360	COG2198	Histidine kinase
GOP56_RS15360	COG0784	Response regulator, receiver
GOP56_RS15360	COG2205	protein histidine kinase activity
GOP56_RS15365	COG0457	Tetratricopeptide repeat
GOP56_RS15365	COG0463	Glycosyl transferase, family 2
GOP56_RS15370	COG1187	pseudouridine synthase activity
GOP56_RS15375	COG0861	Integral membrane protein TerC family
GOP56_RS15380	COG2814	Major facilitator Superfamily
GOP56_RS15405	COG1595	DNA-templated transcription, initiation
GOP56_RS15430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GOP56_RS15435	COG1482	cell wall glycoprotein biosynthetic process
GOP56_RS15440	COG0745	RESPONSE REGULATOR receiver
GOP56_RS15460	COG2271	Major facilitator Superfamily
GOP56_RS15465	COG0784	Response regulator, receiver
GOP56_RS15470	COG4191	Histidine kinase
GOP56_RS15475	COG0765	amino acid transport
GOP56_RS15480	COG0765	amino acid transport
GOP56_RS15495	COG1649	PFAM Uncharacterised BCR, COG1649
GOP56_RS15500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS15505	COG0840	transmembrane signaling receptor activity
GOP56_RS15510	COG2226	methyltransferase
GOP56_RS15515	COG2226	methyltransferase
GOP56_RS15515	COG1073	alpha beta
GOP56_RS15520	COG0653	protein targeting
GOP56_RS15525	COG3239	Fatty acid desaturase
GOP56_RS15530	COG2819	hydrolase of the alpha beta superfamily
GOP56_RS15580	COG0840	transmembrane signaling receptor activity
GOP56_RS15595	COG1595	DNA-templated transcription, initiation
GOP56_RS15600	COG0561	phosphatase activity
GOP56_RS15610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOP56_RS15645	COG1733	regulation of RNA biosynthetic process
GOP56_RS15650	COG2814	Major facilitator Superfamily
GOP56_RS15655	COG0656	L-ascorbic acid biosynthetic process
GOP56_RS15680	COG1151	hydroxylamine reductase activity
GOP56_RS15685	COG0579	oxidoreductase
GOP56_RS15705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GOP56_RS15725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GOP56_RS15735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GOP56_RS15740	COG4853	Protein conserved in bacteria
GOP56_RS15745	COG4863	YycH protein
GOP56_RS15750	COG5002	protein histidine kinase activity
GOP56_RS15760	COG0739	heme binding
GOP56_RS15775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GOP56_RS15780	COG0305	Participates in initiation and elongation during chromosome replication
GOP56_RS15785	COG0359	binds to the 23S rRNA
GOP56_RS15790	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GOP56_RS15800	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GOP56_RS15805	COG0629	single-stranded DNA binding
GOP56_RS15810	COG0360	Binds together with S18 to 16S ribosomal RNA
GOP56_RS15815	COG0012	GTP binding
GOP56_RS15830	COG1164	Oligoendopeptidase f
GOP56_RS15835	COG4481	Protein conserved in bacteria
GOP56_RS15840	COG0668	transmembrane transport
GOP56_RS15855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GOP56_RS15860	COG1475	DNA binding
GOP56_RS15865	COG1192	Involved in chromosome partitioning
GOP56_RS15870	COG1475	DNA binding
GOP56_RS15875	COG0357	Ribosomal RNA small subunit methyltransferase G
GOP56_RS15880	COG0445	tRNA wobble uridine modification
GOP56_RS15885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GOP56_RS15890	COG1847	R3H domain protein
GOP56_RS15895	COG0706	membrane insertase activity
GOP56_RS15900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GOP56_RS15905	COG0594	ribonuclease P activity
GOP56_RS15910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GOP56_RS15915	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GOP56_RS15920	COG0592	DNA-directed DNA polymerase activity
GOP56_RS15925	COG2501	S4 domain
GOP56_RS15930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GOP56_RS15940	COG0187	DNA topoisomerase II activity
GOP56_RS15950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GOP56_RS15955	COG0180	Tryptophanyl-tRNA synthetase
GOP56_RS15965	COG1136	(ABC) transporter
GOP56_RS15970	COG0577	efflux transmembrane transporter activity
GOP56_RS15975	COG4106	trans-aconitate 2-methyltransferase activity
GOP56_RS15980	COG2267	carboxylic ester hydrolase activity
GOP56_RS15985	COG0156	8-amino-7-oxononanoate synthase activity
GOP56_RS15990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GOP56_RS16000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GOP56_RS16010	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS16015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GOP56_RS16045	COG0517	IMP dehydrogenase activity
GOP56_RS16045	COG0516	GMP reductase activity
GOP56_RS16055	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GOP56_RS16060	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GOP56_RS16065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GOP56_RS16070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GOP56_RS16075	COG2224	Isocitrate lyase
GOP56_RS16090	COG1191	sigma factor activity
GOP56_RS16100	COG0590	tRNA wobble adenosine to inosine editing
GOP56_RS16105	COG1187	pseudouridine synthase activity
GOP56_RS16115	COG3852	Histidine kinase
GOP56_RS16120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GOP56_RS16125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GOP56_RS16130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GOP56_RS16170	COG1982	Orn Lys Arg decarboxylase major
GOP56_RS16180	COG3870	Protein conserved in bacteria
GOP56_RS16185	COG1728	Protein conserved in bacteria
GOP56_RS16190	COG0470	DNA polymerase III
GOP56_RS16195	COG1774	PSP1 C-terminal conserved region
GOP56_RS16200	COG4467	Involved in initiation control of chromosome replication
GOP56_RS16205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GOP56_RS16210	COG2827	Endonuclease containing a URI domain
GOP56_RS16215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GOP56_RS16220	COG2002	toxin-antitoxin pair type II binding
GOP56_RS16225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOP56_RS16225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GOP56_RS16230	COG0084	hydrolase, TatD family'
GOP56_RS16235	COG1388	LysM domain
GOP56_RS16235	COG3584	3D domain protein
GOP56_RS16245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GOP56_RS16250	COG4466	Protein conserved in bacteria
GOP56_RS16260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GOP56_RS16265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GOP56_RS16270	COG2088	sporulation resulting in formation of a cellular spore
GOP56_RS16280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GOP56_RS16285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GOP56_RS16290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GOP56_RS16295	COG0193	aminoacyl-tRNA hydrolase activity
GOP56_RS16305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GOP56_RS16315	COG2002	toxin-antitoxin pair type II binding
GOP56_RS16320	COG2244	polysaccharide biosynthetic process
GOP56_RS16325	COG3956	TIGRFAM MazG family protein
GOP56_RS16330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GOP56_RS16350	COG2208	phosphoserine phosphatase activity
GOP56_RS16355	COG2304	oxidoreductase activity
GOP56_RS16360	COG0515	serine threonine protein kinase
GOP56_RS16385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GOP56_RS16390	COG0561	phosphatase activity
GOP56_RS16395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GOP56_RS16405	COG0803	Belongs to the bacterial solute-binding protein 9 family
GOP56_RS16415	COG1121	(ABC) transporter
GOP56_RS16420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GOP56_RS16425	COG0735	belongs to the Fur family
GOP56_RS16435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GOP56_RS16445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GOP56_RS16465	COG2894	cell division
GOP56_RS16525	COG1595	DNA-templated transcription, initiation
GOP56_RS16530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GOP56_RS16535	COG1733	regulation of RNA biosynthetic process
GOP56_RS16540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GOP56_RS16545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GOP56_RS16550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GOP56_RS16555	COG0512	Glutamine amidotransferase of anthranilate synthase
GOP56_RS16560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GOP56_RS16565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GOP56_RS16570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GOP56_RS16575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GOP56_RS16580	COG1396	sequence-specific DNA binding
GOP56_RS16585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GOP56_RS16590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GOP56_RS16640	COG3880	PFAM UvrB UvrC protein
GOP56_RS16645	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GOP56_RS16650	COG0542	response to heat
GOP56_RS16655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GOP56_RS16660	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GOP56_RS16665	COG1183	phosphatidylcholine synthase activity
GOP56_RS16675	COG4956	integral membrane protein (PIN domain superfamily)
GOP56_RS16685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GOP56_RS16690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GOP56_RS16695	COG1045	serine acetyltransferase
GOP56_RS16700	COG0215	cysteine-tRNA ligase activity
GOP56_RS16705	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GOP56_RS16710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GOP56_RS16715	COG3688	RNA-binding protein containing a PIN domain
GOP56_RS16725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GOP56_RS16730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GOP56_RS16735	COG0250	Participates in transcription elongation, termination and antitermination
GOP56_RS16740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GOP56_RS16745	COG0081	regulation of translation
GOP56_RS16750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GOP56_RS16755	COG0222	ribosome binding
GOP56_RS16760	COG2813	Specifically methylates the guanine in position
GOP56_RS16765	COG0085	RNA polymerase activity
GOP56_RS16770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GOP56_RS16775	COG1358	cellular component organization or biogenesis
GOP56_RS16780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GOP56_RS16785	COG0049	tRNA binding
GOP56_RS16790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GOP56_RS16795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GOP56_RS16805	COG2346	COG2346, Truncated hemoglobins
GOP56_RS16810	COG0051	transcription antitermination factor activity, RNA binding
GOP56_RS16815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GOP56_RS16820	COG0088	Forms part of the polypeptide exit tunnel
GOP56_RS16825	COG0089	rRNA binding
GOP56_RS16830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GOP56_RS16835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GOP56_RS16840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GOP56_RS16845	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GOP56_RS16850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GOP56_RS16855	COG0255	Belongs to the universal ribosomal protein uL29 family
GOP56_RS16860	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GOP56_RS16865	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GOP56_RS16870	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GOP56_RS16875	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GOP56_RS16880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GOP56_RS16885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GOP56_RS16890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GOP56_RS16895	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GOP56_RS16900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GOP56_RS16905	COG1841	ribosomal large subunit assembly
GOP56_RS16910	COG0200	Binds to the 23S rRNA
GOP56_RS16915	COG0201	protein transport
GOP56_RS16920	COG0563	adenylate kinase activity
GOP56_RS16925	COG0024	Methionine aminopeptidase
GOP56_RS16930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GOP56_RS16935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GOP56_RS16940	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GOP56_RS16945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GOP56_RS16950	COG0202	RNA polymerase activity
GOP56_RS16955	COG0203	ribosomal protein L17
GOP56_RS16960	COG1122	ATPase activity
GOP56_RS16965	COG1122	ATPase activity
GOP56_RS16970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GOP56_RS16975	COG0101	tRNA pseudouridine synthase activity
GOP56_RS16980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GOP56_RS16985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GOP56_RS16995	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS17000	COG0489	protein tyrosine kinase activity
GOP56_RS17010	COG2194	sulfuric ester hydrolase activity
GOP56_RS17015	COG0726	polysaccharide deacetylase
GOP56_RS17105	COG0010	Belongs to the arginase family
GOP56_RS17110	COG1595	DNA-templated transcription, initiation
GOP56_RS17115	COG5662	AntiSigma factor
GOP56_RS17120	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GOP56_RS17125	COG4856	YbbR-like protein
GOP56_RS17130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GOP56_RS17175	COG0210	DNA helicase
GOP56_RS17245	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GOP56_RS17295	COG0583	DNA-binding transcription factor activity
GOP56_RS17305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GOP56_RS17310	COG0523	cobalamin synthesis protein
GOP56_RS17330	COG0372	Belongs to the citrate synthase family
GOP56_RS17335	COG2079	MmgE PrpD family protein
GOP56_RS17340	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GOP56_RS17350	COG1960	acyl-CoA dehydrogenase activity
GOP56_RS17360	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS17385	COG1309	transcriptional regulator
GOP56_RS17410	COG0475	glutathione-regulated potassium exporter activity
GOP56_RS17425	COG1328	CTP reductase activity
GOP56_RS17425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GOP56_RS17435	COG0243	molybdopterin cofactor binding
GOP56_RS17445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS17445	COG2207	Transcriptional regulator
GOP56_RS17450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS17455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS17460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS17465	COG2259	Doxx family
GOP56_RS17475	COG0745	RESPONSE REGULATOR receiver
GOP56_RS17480	COG5002	protein histidine kinase activity
GOP56_RS17505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GOP56_RS17515	COG0586	Pfam SNARE associated Golgi protein
GOP56_RS17525	COG1132	(ABC) transporter
GOP56_RS17530	COG1132	(ABC) transporter
GOP56_RS17535	COG2311	Membrane
GOP56_RS17540	COG0577	efflux transmembrane transporter activity
GOP56_RS17545	COG1136	(ABC) transporter
GOP56_RS17550	COG2602	Beta-lactamase
GOP56_RS17560	COG0768	penicillin binding
GOP56_RS17570	COG1414	Transcriptional regulator
GOP56_RS17575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GOP56_RS17595	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GOP56_RS17600	COG1984	allophanate hydrolase subunit 2
GOP56_RS17605	COG5583	Uncharacterized small protein (DUF2292)
GOP56_RS17610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GOP56_RS17615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GOP56_RS17620	COG4208	sulfate ABC transporter
GOP56_RS17625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GOP56_RS17630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS17635	COG0673	inositol 2-dehydrogenase activity
GOP56_RS17640	COG0589	response to stress
GOP56_RS17645	COG0500	methyltransferase
GOP56_RS17650	COG0446	pyridine nucleotide-disulphide oxidoreductase
GOP56_RS17655	COG1937	Protein conserved in bacteria
GOP56_RS17660	COG0733	neurotransmitter:sodium symporter activity
GOP56_RS17665	COG0783	Belongs to the Dps family
GOP56_RS17675	COG1263	PTS System
GOP56_RS17675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GOP56_RS17675	COG2190	(PTS) system
GOP56_RS17695	COG2258	MOSC domain
GOP56_RS17710	COG1914	H( )-stimulated, divalent metal cation uptake system
GOP56_RS17715	COG0288	reversible hydration of carbon dioxide
GOP56_RS17720	COG4166	transmembrane transport
GOP56_RS17725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GOP56_RS17730	COG0746	molybdenum cofactor guanylyltransferase activity
GOP56_RS17735	COG1763	Mo-molybdopterin cofactor biosynthetic process
GOP56_RS17745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GOP56_RS17750	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GOP56_RS17760	COG2205	protein histidine kinase activity
GOP56_RS17770	COG5609	conserved protein (DUF2294)
GOP56_RS17855	COG0681	Belongs to the peptidase S26 family
GOP56_RS17860	COG4585	Histidine kinase
GOP56_RS17865	COG2197	response regulator
GOP56_RS17885	COG2070	2-Nitropropane dioxygenase
GOP56_RS17890	COG0583	DNA-binding transcription factor activity
GOP56_RS17895	COG0372	Belongs to the citrate synthase family
GOP56_RS17900	COG4585	Histidine kinase
GOP56_RS17905	COG2197	response regulator
GOP56_RS17935	COG1271	oxidase subunit
GOP56_RS17940	COG1294	oxidase, subunit
GOP56_RS17945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GOP56_RS17960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GOP56_RS17965	COG0573	inorganic phosphate transmembrane transporter activity
GOP56_RS17970	COG0581	inorganic phosphate transmembrane transporter activity
GOP56_RS17980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GOP56_RS17990	COG1971	Probably functions as a manganese efflux pump
GOP56_RS17995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GOP56_RS18005	COG1316	TRANSCRIPTIONal
GOP56_RS18010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GOP56_RS18015	COG2011	ABC-type metal ion transport system permease component
GOP56_RS18020	COG1464	Belongs to the NlpA lipoprotein family
GOP56_RS18030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GOP56_RS18035	COG4166	transmembrane transport
GOP56_RS18040	COG4166	transmembrane transport
GOP56_RS18065	COG2155	Conserved Protein
GOP56_RS18070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GOP56_RS18075	COG0640	Transcriptional regulator
GOP56_RS18085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GOP56_RS18095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GOP56_RS18100	COG0864	Transcriptional regulator
GOP56_RS18105	COG2337	Toxic component of a toxin-antitoxin (TA) module
GOP56_RS18110	COG2183	response to ionizing radiation
GOP56_RS18125	COG3091	SprT-like family
GOP56_RS18130	COG0802	atpase or kinase
GOP56_RS18135	COG1214	PFAM Peptidase M22, glycoprotease
GOP56_RS18140	COG0456	acetyltransferase
GOP56_RS18155	COG0488	(ABC) transporter
GOP56_RS18160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GOP56_RS18165	COG0521	Mo-molybdopterin cofactor biosynthetic process
GOP56_RS18175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GOP56_RS18180	COG0805	protein transport
GOP56_RS18185	COG0670	Belongs to the BI1 family
GOP56_RS18195	COG2340	Cysteine-rich secretory protein family
GOP56_RS18200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GOP56_RS18325	COG0714	Associated with various cellular activities
GOP56_RS18330	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GOP56_RS18335	COG1305	Transglutaminase-like
GOP56_RS18345	COG2252	PERMEase
GOP56_RS18350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GOP56_RS18355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GOP56_RS18360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GOP56_RS18365	COG2309	aminopeptidase activity
GOP56_RS18370	COG1979	alcohol dehydrogenase
GOP56_RS18375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GOP56_RS18380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GOP56_RS18385	COG0047	phosphoribosylformylglycinamidine synthase activity
GOP56_RS18395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GOP56_RS18400	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GOP56_RS18405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GOP56_RS18415	COG0840	transmembrane signaling receptor activity
GOP56_RS18425	COG0702	epimerase
GOP56_RS18435	COG0151	Belongs to the GarS family
GOP56_RS18445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GOP56_RS18455	COG0559	Belongs to the binding-protein-dependent transport system permease family
GOP56_RS18475	COG3858	chitin binding
GOP56_RS18480	COG2205	protein histidine kinase activity
GOP56_RS18480	COG2770	Histidine kinase
GOP56_RS18485	COG0745	RESPONSE REGULATOR receiver
GOP56_RS18490	COG1470	cell adhesion involved in biofilm formation
GOP56_RS18495	COG4496	protein, YerC YecD
GOP56_RS18500	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GOP56_RS18505	COG0210	DNA helicase
GOP56_RS18510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GOP56_RS18525	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS18540	COG0688	phosphatidylethanolamine metabolic process
GOP56_RS18550	COG1595	DNA-templated transcription, initiation
GOP56_RS18555	COG1307	EDD domain protein, DegV family
GOP56_RS18565	COG0154	amidase activity
GOP56_RS18570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GOP56_RS18575	COG2211	Major facilitator Superfamily
GOP56_RS18580	COG1136	(ABC) transporter
GOP56_RS18585	COG0577	efflux transmembrane transporter activity
GOP56_RS18610	COG4555	ABC transporter
GOP56_RS18625	COG4555	ABC transporter
GOP56_RS18630	COG1668	transmembrane transport
GOP56_RS18635	COG1940	carbohydrate kinase activity
GOP56_RS18640	COG1597	lipid kinase activity
GOP56_RS18645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GOP56_RS18680	COG1819	glycosyl
GOP56_RS18715	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS18735	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS18785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOP56_RS18795	COG0840	transmembrane signaling receptor activity
GOP56_RS18810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS18815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOP56_RS18820	COG0733	neurotransmitter:sodium symporter activity
GOP56_RS18825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOP56_RS18845	COG2226	methyltransferase
GOP56_RS18855	COG1132	(ABC) transporter
GOP56_RS18880	COG1131	(ABC) transporter
GOP56_RS18915	COG0028	Belongs to the TPP enzyme family
GOP56_RS18935	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS18940	COG0454	-acetyltransferase
GOP56_RS18955	COG1988	membrane-bound metal-dependent
GOP56_RS18960	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GOP56_RS18965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GOP56_RS18970	COG2066	Belongs to the glutaminase family
GOP56_RS18990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOP56_RS18995	COG1742	UPF0060 membrane protein
GOP56_RS19005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GOP56_RS19010	COG0833	amino acid
GOP56_RS19015	COG3829	transcription factor binding
GOP56_RS19020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOP56_RS19025	COG0656	L-ascorbic acid biosynthetic process
GOP56_RS19035	COG0529	Catalyzes the synthesis of activated sulfate
GOP56_RS19045	COG0720	synthase
GOP56_RS19055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GOP56_RS19060	COG0805	protein transport
GOP56_RS19065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GOP56_RS19080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GOP56_RS19090	COG0351	phosphomethylpyrimidine kinase
GOP56_RS19125	COG1694	Mazg nucleotide pyrophosphohydrolase
GOP56_RS19150	COG3876	Protein conserved in bacteria
GOP56_RS19155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GOP56_RS19160	COG1360	Flagellar Motor Protein
GOP56_RS19170	COG1279	arginine transmembrane transporter activity
GOP56_RS19175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GOP56_RS19180	COG4844	belongs to the
GOP56_RS19215	COG0577	efflux transmembrane transporter activity
GOP56_RS19220	COG1136	(ABC) transporter
GOP56_RS19225	COG1566	PFAM secretion protein HlyD family protein
GOP56_RS19230	COG0166	Belongs to the GPI family
GOP56_RS19235	COG0166	Belongs to the GPI family
GOP56_RS19250	COG3858	chitin binding
GOP56_RS19260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GOP56_RS19290	COG1968	undecaprenyl-diphosphatase activity
GOP56_RS19295	COG2996	Protein conserved in bacteria
GOP56_RS19300	COG2124	cytochrome p450
GOP56_RS19305	COG1309	transcriptional regulator
GOP56_RS19320	COG1725	Transcriptional regulator
GOP56_RS19325	COG1131	(ABC) transporter
GOP56_RS19335	COG3290	protein histidine kinase activity
GOP56_RS19335	COG3829	transcription factor binding
GOP56_RS19340	COG0506	proline dehydrogenase activity
GOP56_RS19360	COG0824	Thioesterase
GOP56_RS19365	COG2814	Major facilitator Superfamily
GOP56_RS19370	COG1794	racemase activity, acting on amino acids and derivatives
GOP56_RS19375	COG0697	spore germination
GOP56_RS19390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GOP56_RS19405	COG0488	(ABC) transporter
GOP56_RS19410	COG0564	pseudouridine synthase activity
GOP56_RS19420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GOP56_RS19425	COG2076	Multidrug Resistance protein
GOP56_RS19430	COG2076	Multidrug Resistance protein
GOP56_RS19435	COG1309	transcriptional regulator
GOP56_RS19450	COG5002	protein histidine kinase activity
GOP56_RS19455	COG0745	RESPONSE REGULATOR receiver
GOP56_RS19460	COG0791	NLP P60 protein
GOP56_RS19470	COG1842	Phage shock protein A
GOP56_RS19480	COG4758	membrane
GOP56_RS19485	COG4585	Histidine kinase
GOP56_RS19490	COG2197	response regulator
GOP56_RS19495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GOP56_RS19515	COG0730	response to heat
GOP56_RS19525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GOP56_RS19530	COG1988	membrane-bound metal-dependent
GOP56_RS19540	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS19550	COG3557	Belongs to the UPF0374 family
GOP56_RS19560	COG1132	(ABC) transporter
GOP56_RS19575	COG2738	Putative neutral zinc metallopeptidase
GOP56_RS19580	COG0070	glutamate synthase
GOP56_RS19580	COG0069	glutamate synthase activity
GOP56_RS19580	COG0067	glutamate synthase
GOP56_RS19590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GOP56_RS19595	COG4555	ABC transporter
GOP56_RS19615	COG0546	phosphoglycolate phosphatase activity
GOP56_RS19625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GOP56_RS19630	COG1363	Peptidase, m42
GOP56_RS19635	COG2226	methyltransferase
GOP56_RS19640	COG2096	Adenosyltransferase
GOP56_RS19645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS19650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GOP56_RS19655	COG0735	belongs to the Fur family
GOP56_RS19750	COG2233	PERMEase
GOP56_RS19760	COG0328	RNA-DNA hybrid ribonuclease activity
GOP56_RS19765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GOP56_RS19770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GOP56_RS19790	COG2718	Belongs to the UPF0229 family
GOP56_RS19795	COG2766	serine protein kinase
GOP56_RS19820	COG0596	Alpha beta hydrolase
GOP56_RS19860	COG0737	Belongs to the 5'-nucleotidase family
GOP56_RS19870	COG2267	carboxylic ester hydrolase activity
GOP56_RS19880	COG2244	polysaccharide biosynthetic process
GOP56_RS19885	COG0693	protein deglycase activity
GOP56_RS19890	COG0697	spore germination
GOP56_RS19910	COG2423	ornithine cyclodeaminase activity
GOP56_RS19915	COG2719	SpoVR family
GOP56_RS19920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GOP56_RS19980	COG1396	sequence-specific DNA binding
GOP56_RS20035	COG3723	Recombinational DNA repair protein, rece pathway
GOP56_RS20135	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS20185	COG3290	protein histidine kinase activity
GOP56_RS20190	COG4565	transcriptional regulatory protein
GOP56_RS20200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GOP56_RS20215	COG0745	RESPONSE REGULATOR receiver
GOP56_RS20220	COG5002	protein histidine kinase activity
GOP56_RS20230	COG1136	(ABC) transporter
GOP56_RS20235	COG0577	efflux transmembrane transporter activity
GOP56_RS20235	COG1136	(ABC) transporter
GOP56_RS20250	COG0277	FAD linked oxidase domain protein
GOP56_RS20270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GOP56_RS20275	COG0583	DNA-binding transcription factor activity
GOP56_RS20295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS20310	COG1349	DNA-binding transcription factor activity
GOP56_RS20315	COG1105	Belongs to the carbohydrate kinase PfkB family
GOP56_RS20320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GOP56_RS20320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS20320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GOP56_RS20325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GOP56_RS20340	COG4264	IucA IucC family
GOP56_RS20360	COG1082	Xylose isomerase domain protein TIM barrel
GOP56_RS20365	COG3693	PFAM glycoside hydrolase, family 10
GOP56_RS20370	COG0640	Transcriptional regulator
GOP56_RS20375	COG2363	Small membrane protein
GOP56_RS20380	COG1272	protein, Hemolysin III
GOP56_RS20385	COG0513	Belongs to the DEAD box helicase family
GOP56_RS20405	COG5002	protein histidine kinase activity
GOP56_RS20410	COG2855	membrane
GOP56_RS20450	COG0189	ligase activity
GOP56_RS20455	COG0189	ligase activity
GOP56_RS20465	COG4399	Belongs to the UPF0754 family
GOP56_RS20485	COG4109	DRTGG domain
GOP56_RS20500	COG0587	DNA-directed DNA polymerase activity
GOP56_RS20505	COG0281	malic enzyme
GOP56_RS20510	COG2186	Transcriptional regulator
GOP56_RS20520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GOP56_RS20525	COG0825	malonyl-CoA metabolic process
GOP56_RS20530	COG0205	6-phosphofructokinase activity
GOP56_RS20540	COG0824	Thioesterase
GOP56_RS20550	COG0628	permease
GOP56_RS20555	COG0372	Belongs to the citrate synthase family
GOP56_RS20560	COG0538	isocitrate dehydrogenase activity
GOP56_RS20565	COG0039	L-malate dehydrogenase activity
GOP56_RS20570	COG0745	RESPONSE REGULATOR receiver
GOP56_RS20575	COG5002	protein histidine kinase activity
GOP56_RS20580	COG2720	vancomycin resistance protein
GOP56_RS20585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GOP56_RS20595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOP56_RS20595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GOP56_RS20600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GOP56_RS20610	COG0739	heme binding
GOP56_RS20610	COG1196	nuclear chromosome segregation
GOP56_RS20610	COG0741	lytic transglycosylase activity
GOP56_RS20615	COG2207	Transcriptional regulator
GOP56_RS20620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GOP56_RS20625	COG3693	PFAM glycoside hydrolase, family 10
GOP56_RS20635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GOP56_RS20645	COG1484	DNA-dependent DNA replication
GOP56_RS20655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GOP56_RS20665	COG2207	Transcriptional regulator
GOP56_RS20670	COG3397	chitin binding
GOP56_RS20675	COG3397	chitin binding
GOP56_RS20680	COG2188	Transcriptional regulator
GOP56_RS20690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GOP56_RS20690	COG1263	PTS System
GOP56_RS20695	COG0366	Alpha amylase catalytic
GOP56_RS20705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS20735	COG0842	Transport permease protein
GOP56_RS20735	COG1129	ABC transporter
GOP56_RS20745	COG0667	Aldo Keto reductase
GOP56_RS20750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GOP56_RS20750	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS20750	COG3321	synthase
GOP56_RS20750	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS20750	COG0300	oxidoreductase activity
GOP56_RS20830	COG0840	transmembrane signaling receptor activity
GOP56_RS20835	COG0490	domain, Protein
GOP56_RS20840	COG0475	glutathione-regulated potassium exporter activity
GOP56_RS20855	COG1595	DNA-templated transcription, initiation
GOP56_RS20870	COG0745	RESPONSE REGULATOR receiver
GOP56_RS20875	COG2205	protein histidine kinase activity
GOP56_RS20905	COG0656	L-ascorbic acid biosynthetic process
GOP56_RS20910	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS20915	COG1846	Transcriptional regulator
GOP56_RS20950	COG2267	carboxylic ester hydrolase activity
GOP56_RS20955	COG0697	spore germination
GOP56_RS20965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GOP56_RS20980	COG1144	Oxidoreductase
GOP56_RS20985	COG0674	pyruvate-flavodoxin oxidoreductase activity
GOP56_RS20990	COG1268	BioY protein
GOP56_RS21055	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GOP56_RS21065	COG2801	Transposase and inactivated derivatives
GOP56_RS21075	COG0814	amino acid
GOP56_RS21080	COG0697	spore germination
GOP56_RS21085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS21090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS21095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS21105	COG1053	succinate dehydrogenase
GOP56_RS21105	COG3976	FMN-binding domain protein
GOP56_RS21120	COG0561	phosphatase activity
GOP56_RS21125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GOP56_RS21130	COG2146	nitrite reductase [NAD(P)H] activity
GOP56_RS21140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GOP56_RS21150	COG3711	transcriptional antiterminator
GOP56_RS21160	COG0246	Mannitol dehydrogenase
GOP56_RS21165	COG1509	lysine 2,3-aminomutase activity
GOP56_RS21175	COG2814	Major facilitator Superfamily
GOP56_RS21180	COG1164	Oligoendopeptidase f
GOP56_RS21185	COG2195	Cleaves the N-terminal amino acid of tripeptides
GOP56_RS21190	COG2204	response regulator
GOP56_RS21195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GOP56_RS21200	COG1012	belongs to the aldehyde dehydrogenase family
GOP56_RS21225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GOP56_RS21240	COG3336	cytochrome c oxidase
GOP56_RS21255	COG3773	Cell wall hydrolase
GOP56_RS21260	COG0531	amino acid
GOP56_RS21280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GOP56_RS21290	COG1252	NADH dehydrogenase
GOP56_RS21300	COG0142	geranyltranstransferase activity
GOP56_RS21335	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GOP56_RS21340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GOP56_RS21350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GOP56_RS21360	COG1122	ATPase activity
GOP56_RS21385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GOP56_RS21390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GOP56_RS21395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GOP56_RS21400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GOP56_RS21405	COG0626	cystathionine gamma-synthase activity
GOP56_RS21410	COG0626	cystathionine gamma-synthase activity
GOP56_RS21420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GOP56_RS21425	COG0175	sulfate reduction
GOP56_RS21430	COG2046	Belongs to the sulfate adenylyltransferase family
GOP56_RS21435	COG0028	Belongs to the TPP enzyme family
GOP56_RS21440	COG0440	acetolactate synthase activity
GOP56_RS21445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GOP56_RS21450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GOP56_RS21455	COG0473	3-isopropylmalate dehydrogenase activity
GOP56_RS21460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GOP56_RS21470	COG1741	Belongs to the pirin family
GOP56_RS21475	COG0521	Mo-molybdopterin cofactor biosynthetic process
GOP56_RS21485	COG0586	Pfam SNARE associated Golgi protein
GOP56_RS21495	COG1363	Peptidase, m42
GOP56_RS21505	COG0569	domain protein
GOP56_RS21510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GOP56_RS21515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GOP56_RS21525	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GOP56_RS21535	COG1193	negative regulation of DNA recombination
GOP56_RS21540	COG3766	membrane
GOP56_RS21545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GOP56_RS21550	COG2362	D-Aminopeptidase
GOP56_RS21555	COG0438	transferase activity, transferring glycosyl groups
GOP56_RS21580	COG0728	peptidoglycan biosynthetic process
GOP56_RS21610	COG1595	DNA-templated transcription, initiation
GOP56_RS21620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GOP56_RS21625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GOP56_RS21630	COG1120	ATPase activity
GOP56_RS21635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GOP56_RS21645	COG2264	protein methyltransferase activity
GOP56_RS21655	COG1316	TRANSCRIPTIONal
GOP56_RS21660	COG0318	PFAM AMP-dependent synthetase and ligase
GOP56_RS21665	COG1309	transcriptional regulator
GOP56_RS21670	COG1024	Enoyl-CoA hydratase
GOP56_RS21675	COG2086	electron transfer activity
GOP56_RS21680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GOP56_RS21690	COG3118	belongs to the thioredoxin family
GOP56_RS21695	COG0322	excinuclease ABC activity
GOP56_RS21700	COG1028	Short-chain dehydrogenase reductase Sdr
GOP56_RS21715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GOP56_RS21730	COG2009	succinate dehydrogenase
GOP56_RS21735	COG1053	succinate dehydrogenase
GOP56_RS21740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GOP56_RS21755	COG2822	iron ion transport
GOP56_RS21760	COG2837	iron assimilation
GOP56_RS21765	COG0672	)-iron permease
GOP56_RS21770	COG3711	transcriptional antiterminator
GOP56_RS21775	COG1263	PTS System
GOP56_RS21775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GOP56_RS21775	COG2190	(PTS) system
GOP56_RS21780	COG2723	6-phospho-beta-galactosidase activity
GOP56_RS21785	COG2197	response regulator
GOP56_RS21790	COG3859	Proton-coupled thiamine transporter YuaJ
GOP56_RS21795	COG2169	Transcriptional regulator
GOP56_RS21805	COG0778	Nitroreductase
GOP56_RS21830	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GOP56_RS21860	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GOP56_RS21865	COG1492	cobalamin metabolic process
GOP56_RS21870	COG0310	cobalt ion transport
GOP56_RS21875	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GOP56_RS21885	COG1122	ATPase activity
GOP56_RS21890	COG0776	regulation of translation
GOP56_RS21895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GOP56_RS21900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GOP56_RS21905	COG0789	Transcriptional regulator
GOP56_RS21910	COG2814	Major facilitator Superfamily
GOP56_RS21915	COG5401	PFAM Sporulation and spore germination
GOP56_RS21920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GOP56_RS21925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GOP56_RS21930	COG0622	Phosphoesterase
GOP56_RS21935	COG0544	peptidyl-prolyl cis-trans isomerase activity
GOP56_RS21940	COG0740	serine-type endopeptidase activity
GOP56_RS21945	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GOP56_RS21950	COG0470	DNA polymerase III
GOP56_RS21950	COG1067	ATP-dependent peptidase activity
GOP56_RS21960	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GOP56_RS21965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GOP56_RS21975	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GOP56_RS21980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GOP56_RS21985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GOP56_RS21985	COG1648	precorrin-2 dehydrogenase activity
GOP56_RS21990	COG0181	hydroxymethylbilane synthase activity
GOP56_RS21995	COG1587	Uroporphyrinogen-III synthase
GOP56_RS21995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GOP56_RS22000	COG0113	porphobilinogen synthase activity
GOP56_RS22010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GOP56_RS22025	COG1388	LysM domain
GOP56_RS22045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GOP56_RS22050	COG0525	valine-tRNA ligase activity
GOP56_RS22055	COG0285	dihydrofolate synthase activity
GOP56_RS22060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GOP56_RS22065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GOP56_RS22080	COG0424	maF-like protein
GOP56_RS22085	COG2003	Belongs to the UPF0758 family
GOP56_RS22090	COG1077	Cell shape determining protein MreB Mrl
GOP56_RS22095	COG1792	Involved in formation and maintenance of cell shape
GOP56_RS22110	COG0850	regulation of cytokinetic process
GOP56_RS22115	COG2894	cell division
GOP56_RS22120	COG0772	Belongs to the SEDS family
GOP56_RS22125	COG1278	Cold shock
GOP56_RS22135	COG1994	Peptidase M50
GOP56_RS22140	COG1530	ribonuclease E activity
GOP56_RS22145	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GOP56_RS22150	COG2868	ribosomal protein
GOP56_RS22155	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GOP56_RS22165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GOP56_RS22175	COG4492	Belongs to the UPF0735 family
GOP56_RS22180	COG0460	homoserine dehydrogenase
GOP56_RS22185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GOP56_RS22190	COG0083	homoserine kinase activity
GOP56_RS22195	COG0077	Prephenate dehydratase
GOP56_RS22200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GOP56_RS22215	COG0584	glycerophosphoryl diester phosphodiesterase
GOP56_RS22230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GOP56_RS22250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GOP56_RS22255	COG0632	four-way junction helicase activity
GOP56_RS22260	COG2255	four-way junction helicase activity
GOP56_RS22265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GOP56_RS22275	COG1862	Preprotein translocase
GOP56_RS22285	COG0598	Magnesium transport protein CorA
GOP56_RS22290	COG2323	membrane
GOP56_RS22295	COG2244	polysaccharide biosynthetic process
GOP56_RS22305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOP56_RS22305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOP56_RS22310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GOP56_RS22315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GOP56_RS22320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GOP56_RS22320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GOP56_RS22325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GOP56_RS22330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GOP56_RS22335	COG1490	D-aminoacyl-tRNA deacylase activity
GOP56_RS22340	COG4991	sh3 domain protein
GOP56_RS22340	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS22340	COG3103	Sh3 type 3 domain protein
GOP56_RS22345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GOP56_RS22350	COG0124	histidyl-tRNA synthetase
GOP56_RS22355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GOP56_RS22360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GOP56_RS22370	COG1959	2 iron, 2 sulfur cluster binding
GOP56_RS22375	COG1104	cysteine desulfurase activity
GOP56_RS22380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GOP56_RS22395	COG0628	permease
GOP56_RS22400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GOP56_RS22405	COG4472	Bacterial protein of unknown function (DUF965)
GOP56_RS22415	COG3906	Belongs to the UPF0473 family
GOP56_RS22430	COG4122	O-methyltransferase activity
GOP56_RS22445	COG0572	uridine kinase
GOP56_RS22450	COG0768	penicillin binding
GOP56_RS22465	COG0733	neurotransmitter:sodium symporter activity
GOP56_RS22475	COG2824	Alkylphosphonate utilization operon protein PhnA
GOP56_RS22480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GOP56_RS22510	COG0456	acetyltransferase
GOP56_RS22510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GOP56_RS22520	COG1376	ErfK ybiS ycfS ynhG family protein
GOP56_RS22525	COG2807	transmembrane transport
GOP56_RS22540	COG1413	lyase activity
GOP56_RS22550	COG4166	transmembrane transport
GOP56_RS22555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GOP56_RS22560	COG2910	NAD(P)H-binding
GOP56_RS22570	COG0534	Mate efflux family protein
GOP56_RS22575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GOP56_RS22585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GOP56_RS22590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GOP56_RS22595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GOP56_RS22600	COG1534	Rna-binding protein
GOP56_RS22605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GOP56_RS22610	COG1713	HD superfamily hydrolase involved in NAD metabolism
GOP56_RS22615	COG0799	negative regulation of ribosome biogenesis
GOP56_RS22620	COG2226	methyltransferase
GOP56_RS22630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GOP56_RS22635	COG1555	photosystem II stabilization
GOP56_RS22635	COG1596	polysaccharide export
GOP56_RS22640	COG0367	asparagine synthase
GOP56_RS22645	COG2131	deaminase
GOP56_RS22650	COG2333	competence protein COMEC
GOP56_RS22650	COG0658	competence protein
GOP56_RS22655	COG1595	DNA-templated transcription, initiation
GOP56_RS22665	COG1466	dna polymerase III delta subunit
GOP56_RS22670	COG0268	Binds directly to 16S ribosomal RNA
GOP56_RS22680	COG0860	N-Acetylmuramoyl-L-alanine amidase
GOP56_RS22690	COG0444	Belongs to the ABC transporter superfamily
GOP56_RS22695	COG4608	Belongs to the ABC transporter superfamily
GOP56_RS22700	COG0747	negative chemotaxis
GOP56_RS22720	COG0006	proline dipeptidase activity
GOP56_RS22725	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GOP56_RS22730	COG2814	Major facilitator Superfamily
GOP56_RS22735	COG1378	Sugar-specific transcriptional regulator TrmB
GOP56_RS22740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GOP56_RS22745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GOP56_RS22745	COG1321	iron dependent repressor
GOP56_RS22750	COG1121	(ABC) transporter
GOP56_RS22755	COG0803	Belongs to the bacterial solute-binding protein 9 family
GOP56_RS22765	COG0481	GTPase activity
GOP56_RS22770	COG0582	viral genome integration into host DNA
GOP56_RS22795	COG1396	sequence-specific DNA binding
GOP56_RS22825	COG2002	toxin-antitoxin pair type II binding
GOP56_RS22945	COG4695	Portal protein
GOP56_RS22950	COG0740	serine-type endopeptidase activity
GOP56_RS23075	COG1705	Flagellar rod assembly protein muramidase FlgJ
GOP56_RS23120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GOP56_RS23125	COG1420	regulation of RNA biosynthetic process
GOP56_RS23135	COG0443	Heat shock 70 kDa protein
GOP56_RS23145	COG2264	protein methyltransferase activity
GOP56_RS23150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GOP56_RS23155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GOP56_RS23165	COG1380	Effector of murein hydrolase LrgA
GOP56_RS23170	COG1346	cytolysis
GOP56_RS23180	COG1283	sodium-dependent phosphate transmembrane transporter activity
GOP56_RS23190	COG0412	Dienelactone hydrolase
GOP56_RS23195	COG1181	Belongs to the D-alanine--D-alanine ligase family
GOP56_RS23205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GOP56_RS23210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GOP56_RS23215	COG1610	YqeY-like protein
GOP56_RS23220	COG1030	water channel activity
GOP56_RS23225	COG4864	UPF0365 protein
GOP56_RS23235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine