locus-tag	class	description
DA69_RS00010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DA69_RS00035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DA69_RS00060	COG1450	Type ii and iii secretion system protein
DA69_RS00105	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DA69_RS00135	COG0529	Catalyzes the synthesis of activated sulfate
DA69_RS00135	COG2895	sulfate adenylyltransferase (ATP) activity
DA69_RS00140	COG0175	sulfate reduction
DA69_RS00150	COG2885	chlorophyll binding
DA69_RS00150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DA69_RS00155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DA69_RS00160	COG2885	chlorophyll binding
DA69_RS00165	COG0071	Belongs to the small heat shock protein (HSP20) family
DA69_RS00175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA69_RS00180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DA69_RS00185	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DA69_RS00190	COG1137	ATPase activity
DA69_RS00205	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DA69_RS00225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DA69_RS00240	COG0523	cobalamin synthesis protein
DA69_RS00250	COG3609	addiction module antidote protein, CC2985 family
DA69_RS00260	COG2267	carboxylic ester hydrolase activity
DA69_RS00325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DA69_RS00335	COG1960	acyl-CoA dehydrogenase activity
DA69_RS00340	COG1960	acyl-CoA dehydrogenase activity
DA69_RS00345	COG0789	Transcriptional regulator
DA69_RS00355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DA69_RS00360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DA69_RS00365	COG4771	TonB-dependent receptor
DA69_RS00385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DA69_RS00385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA69_RS00400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DA69_RS00405	COG0318	PFAM AMP-dependent synthetase and ligase
DA69_RS00420	COG1131	(ABC) transporter
DA69_RS00425	COG0842	Transport permease protein
DA69_RS00490	COG1742	UPF0060 membrane protein
DA69_RS00500	COG0583	DNA-binding transcription factor activity
DA69_RS00505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DA69_RS00550	COG0538	isocitrate dehydrogenase activity
DA69_RS00560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DA69_RS00565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DA69_RS00575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA69_RS00575	COG3153	acetyltransferase
DA69_RS00580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DA69_RS00585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DA69_RS00600	COG2205	protein histidine kinase activity
DA69_RS00600	COG0784	Response regulator, receiver
DA69_RS00605	COG0477	Major facilitator Superfamily
DA69_RS00615	COG4566	intracellular signal transduction
DA69_RS00620	COG4191	Histidine kinase
DA69_RS00630	COG0840	transmembrane signaling receptor activity
DA69_RS00640	COG0745	RESPONSE REGULATOR receiver
DA69_RS00645	COG0643	Histidine kinase
DA69_RS00645	COG2198	Histidine kinase
DA69_RS00650	COG0835	chemotaxis
DA69_RS00655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DA69_RS00660	COG2201	protein-glutamate methylesterase activity
DA69_RS00665	COG0745	RESPONSE REGULATOR receiver
DA69_RS00680	COG0745	RESPONSE REGULATOR receiver
DA69_RS00695	COG2814	Major facilitator Superfamily
DA69_RS00705	COG1960	acyl-CoA dehydrogenase activity
DA69_RS00735	COG0539	negative regulation of cytoplasmic translation
DA69_RS00755	COG3104	oligopeptide transport
DA69_RS00770	COG0312	modulator of DNA gyrase
DA69_RS00795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DA69_RS00800	COG0109	protoheme IX farnesyltransferase activity
DA69_RS00810	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DA69_RS00830	COG0612	Peptidase, M16
DA69_RS00835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA69_RS00840	COG5001	Diguanylate cyclase
DA69_RS00870	COG0167	dihydroorotate dehydrogenase activity
DA69_RS00890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA69_RS00930	COG4957	zinc ion binding
DA69_RS00955	COG0488	(ABC) transporter
DA69_RS00970	COG2983	Belongs to the UPF0260 family
DA69_RS00995	COG4695	Portal protein
DA69_RS01050	COG3152	Membrane
DA69_RS01080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DA69_RS01085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DA69_RS01100	COG0564	pseudouridine synthase activity
DA69_RS01135	COG1966	Carbon starvation protein
DA69_RS01140	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DA69_RS01165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DA69_RS01170	COG1692	metallophosphoesterase
DA69_RS01185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DA69_RS01200	COG0047	phosphoribosylformylglycinamidine synthase activity
DA69_RS01215	COG1881	PFAM PEBP family protein
DA69_RS01220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DA69_RS01225	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DA69_RS01230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DA69_RS01240	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DA69_RS01255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DA69_RS01265	COG1196	nuclear chromosome segregation
DA69_RS01265	COG0741	lytic transglycosylase activity
DA69_RS01265	COG0739	heme binding
DA69_RS01270	COG1573	uracil-dna glycosylase
DA69_RS01310	COG0751	glycine-tRNA ligase activity
DA69_RS01355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DA69_RS01360	COG3727	T/G mismatch-specific endonuclease activity
DA69_RS01370	COG1595	DNA-templated transcription, initiation
DA69_RS01400	COG0653	protein targeting
DA69_RS01425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DA69_RS01460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DA69_RS01465	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
DA69_RS01470	COG4786	Flagellar basal body rod
DA69_RS01475	COG4786	Flagellar basal body rod
DA69_RS01520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DA69_RS01530	COG0110	maltose O-acetyltransferase activity
DA69_RS01535	COG0469	pyruvate kinase activity
DA69_RS01560	COG2968	Membrane
DA69_RS01565	COG0616	signal peptide processing
DA69_RS01575	COG3023	N-Acetylmuramoyl-L-alanine amidase
DA69_RS01605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DA69_RS01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DA69_RS01630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DA69_RS01645	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DA69_RS01655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DA69_RS01655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DA69_RS01660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DA69_RS01675	COG1194	a g-specific adenine glycosylase
DA69_RS01685	COG0438	transferase activity, transferring glycosyl groups
DA69_RS01695	COG0753	catalase activity
DA69_RS01700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DA69_RS01705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DA69_RS01710	COG1181	Belongs to the D-alanine--D-alanine ligase family
DA69_RS01720	COG0849	cell division
DA69_RS01725	COG4206	TonB-dependent receptor
DA69_RS01735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DA69_RS01740	COG1496	oxidoreductase activity
DA69_RS01755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DA69_RS01785	COG0745	RESPONSE REGULATOR receiver
DA69_RS01790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA69_RS01795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DA69_RS01800	COG0625	glutathione transferase activity
DA69_RS01820	COG1573	uracil-dna glycosylase
DA69_RS01835	COG1766	The M ring may be actively involved in energy transduction
DA69_RS01840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DA69_RS01850	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DA69_RS01855	COG2204	response regulator
DA69_RS01865	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DA69_RS01880	COG3920	Histidine kinase
DA69_RS01890	COG3237	CsbD-like
DA69_RS01920	COG1722	exodeoxyribonuclease VII activity
DA69_RS01925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA69_RS01930	COG0142	geranyltranstransferase activity
DA69_RS01935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DA69_RS01940	COG1702	phosphate starvation-inducible protein PhoH
DA69_RS01955	COG0612	Peptidase, M16
DA69_RS01965	COG1462	curli production assembly transport component CsgG
DA69_RS01975	COG0457	Tetratricopeptide repeat
DA69_RS01975	COG0705	Rhomboid family
DA69_RS01980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DA69_RS01980	COG0517	IMP dehydrogenase activity
DA69_RS02040	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DA69_RS02065	COG0179	Fumarylacetoacetate (FAA) hydrolase
DA69_RS02075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA69_RS02080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DA69_RS02085	COG1228	amidohydrolase
DA69_RS02095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DA69_RS02100	COG0583	DNA-binding transcription factor activity
DA69_RS02135	COG4771	TonB-dependent receptor
DA69_RS02160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DA69_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS02245	COG1595	DNA-templated transcription, initiation
DA69_RS02260	COG0415	Belongs to the DNA photolyase family
DA69_RS02265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DA69_RS02270	COG3040	lipid binding
DA69_RS02285	COG1476	TRANSCRIPTIONal
DA69_RS02295	COG0354	folic acid binding
DA69_RS02300	COG0574	Belongs to the PEP-utilizing enzyme family
DA69_RS02300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DA69_RS02330	COG2301	Belongs to the HpcH HpaI aldolase family
DA69_RS02340	COG1940	carbohydrate kinase activity
DA69_RS02345	COG1956	GAF domain-containing protein
DA69_RS02355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA69_RS02360	COG4232	protein-disulfide reductase activity
DA69_RS02370	COG0642	Histidine kinase
DA69_RS02390	COG2205	protein histidine kinase activity
DA69_RS02400	COG1169	isochorismate synthase
DA69_RS02405	COG1021	2,3-dihydroxybenzoate-AMP ligase
DA69_RS02410	COG3433	isochorismatase activity
DA69_RS02410	COG1535	isochorismatase
DA69_RS02415	COG1535	isochorismatase
DA69_RS02415	COG3433	isochorismatase activity
DA69_RS02420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA69_RS02425	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS02430	COG1741	Belongs to the pirin family
DA69_RS02440	COG0583	DNA-binding transcription factor activity
DA69_RS02470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA69_RS02480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DA69_RS02490	COG0564	pseudouridine synthase activity
DA69_RS02500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DA69_RS02505	COG0564	pseudouridine synthase activity
DA69_RS02535	COG1187	pseudouridine synthase activity
DA69_RS02550	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DA69_RS02555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA69_RS02580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DA69_RS02590	COG0235	Class ii aldolase
DA69_RS02605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DA69_RS02610	COG3474	cytochrome
DA69_RS02630	COG0537	adenosine 5'-monophosphoramidase activity
DA69_RS02635	COG1950	PFAM Membrane protein of
DA69_RS02640	COG1686	Belongs to the peptidase S11 family
DA69_RS02650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DA69_RS02675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DA69_RS02690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DA69_RS02705	COG0557	exoribonuclease II activity
DA69_RS02715	COG0626	cystathionine gamma-synthase activity
DA69_RS02720	COG0668	transmembrane transport
DA69_RS02725	COG1278	Cold shock
DA69_RS02750	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DA69_RS02765	COG3739	integral membrane protein
DA69_RS02770	COG0778	Nitroreductase
DA69_RS02775	COG0494	nUDIX hydrolase
DA69_RS02780	COG1045	serine acetyltransferase
DA69_RS02795	COG2264	protein methyltransferase activity
DA69_RS02810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DA69_RS02815	COG2234	aminopeptidase activity
DA69_RS02835	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DA69_RS02855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DA69_RS02855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DA69_RS02875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DA69_RS02880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DA69_RS02890	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DA69_RS02895	COG2205	protein histidine kinase activity
DA69_RS02900	COG0745	RESPONSE REGULATOR receiver
DA69_RS02920	COG0154	amidase activity
DA69_RS02935	COG2132	Multicopper oxidase
DA69_RS02990	COG4608	Belongs to the ABC transporter superfamily
DA69_RS02995	COG0444	Belongs to the ABC transporter superfamily
DA69_RS03005	COG0601	transmembrane transport
DA69_RS03010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DA69_RS03015	COG1960	acyl-CoA dehydrogenase activity
DA69_RS03020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DA69_RS03025	COG0066	3-isopropylmalate dehydratase activity
DA69_RS03045	COG1335	isochorismatase
DA69_RS03050	COG2188	Transcriptional regulator
DA69_RS03055	COG2188	Transcriptional regulator
DA69_RS03060	COG1012	belongs to the aldehyde dehydrogenase family
DA69_RS03080	COG2226	methyltransferase
DA69_RS03100	COG3046	protein related to deoxyribodipyrimidine photolyase
DA69_RS03110	COG4771	TonB-dependent receptor
DA69_RS03120	COG1012	belongs to the aldehyde dehydrogenase family
DA69_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
DA69_RS03140	COG0385	Bile acid
DA69_RS03150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DA69_RS03185	COG2197	response regulator
DA69_RS03190	COG0187	DNA topoisomerase II activity
DA69_RS03215	COG3189	MarR family transcriptional regulator
DA69_RS03255	COG0114	fumarate hydratase activity
DA69_RS03275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DA69_RS03280	COG0489	protein tyrosine kinase activity
DA69_RS03300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DA69_RS03345	COG4771	TonB-dependent receptor
DA69_RS03345	COG1629	transport
DA69_RS03360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DA69_RS03365	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DA69_RS03375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DA69_RS03390	COG0156	8-amino-7-oxononanoate synthase activity
DA69_RS03400	COG0436	Aminotransferase
DA69_RS03450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DA69_RS03455	COG0730	response to heat
DA69_RS03460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA69_RS03460	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DA69_RS03475	COG0450	alkyl hydroperoxide reductase
DA69_RS03480	COG0640	Transcriptional regulator
DA69_RS03485	COG1473	amidohydrolase
DA69_RS03505	COG2226	methyltransferase
DA69_RS03510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DA69_RS03535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DA69_RS03555	COG3243	poly(R)-hydroxyalkanoic acid synthase
DA69_RS03580	COG1278	Cold shock
DA69_RS03645	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DA69_RS03660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA69_RS03685	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DA69_RS03715	COG0662	Cupin 2, conserved barrel domain protein
DA69_RS03720	COG0372	Belongs to the citrate synthase family
DA69_RS03725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DA69_RS03730	COG0658	competence protein
DA69_RS03730	COG2333	competence protein COMEC
DA69_RS03735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DA69_RS03740	COG4946	Tricorn protease homolog
DA69_RS03740	COG1506	peptidase
DA69_RS03740	COG0823	Involved in the tonB-independent uptake of proteins
DA69_RS03750	COG0297	glycogen (starch) synthase activity
DA69_RS03760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DA69_RS03770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA69_RS03775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA69_RS03780	COG0649	NAD binding
DA69_RS03805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DA69_RS03815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DA69_RS03840	COG1007	ATP synthesis coupled electron transport
DA69_RS03850	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DA69_RS03875	COG0442	prolyl-tRNA aminoacylation
DA69_RS03885	COG1136	(ABC) transporter
DA69_RS03900	COG0052	Belongs to the universal ribosomal protein uS2 family
DA69_RS03905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DA69_RS03910	COG0528	UMP kinase activity
DA69_RS03915	COG0233	cytoplasmic translational termination
DA69_RS03920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DA69_RS03935	COG0750	zinc metalloprotease
DA69_RS03940	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA69_RS03950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DA69_RS03965	COG3494	Protein of unknown function (DUF1009)
DA69_RS03970	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DA69_RS03975	COG0134	indole-3-glycerol-phosphate synthase activity
DA69_RS03980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DA69_RS03995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DA69_RS04005	COG0149	triose-phosphate isomerase activity
DA69_RS04015	COG0504	CTP synthase activity
DA69_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS04025	COG1960	acyl-CoA dehydrogenase activity
DA69_RS04030	COG4771	TonB-dependent receptor
DA69_RS04040	COG0339	signal peptide processing
DA69_RS04070	COG3590	peptidase
DA69_RS04095	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DA69_RS04120	COG2155	Conserved Protein
DA69_RS04145	COG0492	ferredoxin-NADP+ reductase activity
DA69_RS04235	COG3546	catalase activity
DA69_RS04300	COG2003	Belongs to the UPF0758 family
DA69_RS04360	COG0659	secondary active sulfate transmembrane transporter activity
DA69_RS04380	COG0798	PFAM Bile acid sodium symporter
DA69_RS04395	COG1309	transcriptional regulator
DA69_RS04400	COG4771	TonB-dependent receptor
DA69_RS04410	COG0477	Major facilitator Superfamily
DA69_RS04415	COG4948	Mandelate Racemase Muconate Lactonizing
DA69_RS04465	COG1285	pathogenesis
DA69_RS04470	COG2323	membrane
DA69_RS04515	COG1595	DNA-templated transcription, initiation
DA69_RS04570	COG4962	Type ii secretion system protein e
DA69_RS04595	COG3451	type IV secretory pathway VirB4
DA69_RS04630	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DA69_RS04655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DA69_RS04665	COG0084	hydrolase, TatD family'
DA69_RS04670	COG0321	lipoyl(octanoyl) transferase activity
DA69_RS04670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DA69_RS04675	COG1301	dicarboxylic acid transport
DA69_RS04680	COG4206	TonB-dependent receptor
DA69_RS04695	COG1612	heme a metabolic process
DA69_RS04705	COG1764	response to oxidative stress
DA69_RS04730	COG1793	dna ligase
DA69_RS04735	COG0668	transmembrane transport
DA69_RS04740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DA69_RS04745	COG5265	(ABC) transporter
DA69_RS04775	COG4974	Belongs to the 'phage' integrase family
DA69_RS04800	COG1187	pseudouridine synthase activity
DA69_RS04805	COG0742	ribosomal rna small subunit methyltransferase
DA69_RS04820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DA69_RS04830	COG2353	YceI-like domain
DA69_RS04840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DA69_RS04850	COG0259	pyridoxamine-phosphate oxidase activity
DA69_RS04860	COG0572	uridine kinase
DA69_RS04865	COG0318	PFAM AMP-dependent synthetase and ligase
DA69_RS04900	COG1960	acyl-CoA dehydrogenase activity
DA69_RS04905	COG0009	L-threonylcarbamoyladenylate synthase
DA69_RS04915	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS04920	COG3022	response to hydroperoxide
DA69_RS04925	COG0277	FAD linked oxidase domain protein
DA69_RS04935	COG0330	HflC and HflK could
DA69_RS04945	COG0328	RNA-DNA hybrid ribonuclease activity
DA69_RS04950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DA69_RS04955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DA69_RS04960	COG0805	protein transport
DA69_RS04965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DA69_RS04965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DA69_RS04970	COG0347	Belongs to the P(II) protein family
DA69_RS04975	COG0174	glutamine synthetase
DA69_RS04980	COG1473	amidohydrolase
DA69_RS05000	COG0531	amino acid
DA69_RS05005	COG1643	Atp-dependent helicase
DA69_RS05010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DA69_RS05015	COG0116	Belongs to the methyltransferase superfamily
DA69_RS05015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DA69_RS05035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA69_RS05040	COG1120	ATPase activity
DA69_RS05045	COG0741	lytic transglycosylase activity
DA69_RS05050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DA69_RS05065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DA69_RS05075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA69_RS05080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DA69_RS05085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DA69_RS05095	COG2945	thiolester hydrolase activity
DA69_RS05100	COG1959	2 iron, 2 sulfur cluster binding
DA69_RS05105	COG1104	cysteine desulfurase activity
DA69_RS05110	COG0719	Fe-S assembly protein
DA69_RS05115	COG0396	ATPase activity
DA69_RS05120	COG0719	Fe-S assembly protein
DA69_RS05125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DA69_RS05130	COG2151	metal-sulfur cluster biosynthetic enzyme
DA69_RS05135	COG0316	Belongs to the HesB IscA family
DA69_RS05140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DA69_RS05145	COG2011	ABC-type metal ion transport system permease component
DA69_RS05165	COG0513	Belongs to the DEAD box helicase family
DA69_RS05175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DA69_RS05175	COG1754	DNA topoisomerase type I activity
DA69_RS05180	COG0758	DNA mediated transformation
DA69_RS05190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DA69_RS05195	COG0540	Belongs to the ATCase OTCase family
DA69_RS05200	COG2855	membrane
DA69_RS05205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DA69_RS05215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DA69_RS05220	COG0154	amidase activity
DA69_RS05225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DA69_RS05230	COG1741	Belongs to the pirin family
DA69_RS05235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DA69_RS05255	COG1862	Preprotein translocase
DA69_RS05265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DA69_RS05275	COG0640	Transcriptional regulator
DA69_RS05280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DA69_RS05290	COG2807	transmembrane transport
DA69_RS05295	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DA69_RS05315	COG0488	(ABC) transporter
DA69_RS05320	COG2203	Gaf domain
DA69_RS05320	COG3706	GGDEF domain
DA69_RS05320	COG4251	negative regulation of phosphorylation
DA69_RS05320	COG5001	Diguanylate cyclase
DA69_RS05335	COG1706	bacterial-type flagellum-dependent cell motility
DA69_RS05350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DA69_RS05360	COG1611	Belongs to the LOG family
DA69_RS05375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA69_RS05380	COG1301	dicarboxylic acid transport
DA69_RS05385	COG2897	thiosulfate sulfurtransferase activity
DA69_RS05400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA69_RS05425	COG1301	dicarboxylic acid transport
DA69_RS05430	COG0546	phosphoglycolate phosphatase activity
DA69_RS05465	COG0156	8-amino-7-oxononanoate synthase activity
DA69_RS05470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DA69_RS05475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DA69_RS05495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DA69_RS05505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DA69_RS05515	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DA69_RS05535	COG0416	fatty acid biosynthetic process
DA69_RS05540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DA69_RS05545	COG0776	regulation of translation
DA69_RS05570	COG0577	efflux transmembrane transporter activity
DA69_RS05575	COG1136	(ABC) transporter
DA69_RS05580	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DA69_RS05590	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DA69_RS05595	COG2249	NAD(P)H dehydrogenase (quinone) activity
DA69_RS05610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DA69_RS05625	COG1554	hydrolase, family 65, central catalytic
DA69_RS05710	COG0789	Transcriptional regulator
DA69_RS05765	COG0583	DNA-binding transcription factor activity
DA69_RS05775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA69_RS05780	COG0386	Belongs to the glutathione peroxidase family
DA69_RS05785	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA69_RS05795	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA69_RS05795	COG0022	dehydrogenase e1 component
DA69_RS05800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DA69_RS05810	COG0148	phosphopyruvate hydratase activity
DA69_RS05825	COG0579	oxidoreductase
DA69_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
DA69_RS05840	COG0204	Acyl-transferase
DA69_RS05845	COG2259	Doxx family
DA69_RS05850	COG3384	dioxygenase
DA69_RS05870	COG3956	TIGRFAM MazG family protein
DA69_RS05875	COG0025	NhaP-type Na H and K H
DA69_RS05880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DA69_RS05885	COG1923	regulation of RNA biosynthetic process
DA69_RS05890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA69_RS05895	COG2204	response regulator
DA69_RS05900	COG5000	phosphorelay sensor kinase activity
DA69_RS05905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DA69_RS05920	COG1295	ribonuclease BN
DA69_RS05930	COG1058	Belongs to the CinA family
DA69_RS05930	COG1546	Belongs to the CinA family
DA69_RS05940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DA69_RS05990	COG0183	Belongs to the thiolase family
DA69_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS06005	COG2211	Major facilitator Superfamily
DA69_RS06040	COG0587	DNA-directed DNA polymerase activity
DA69_RS06045	COG0626	cystathionine gamma-synthase activity
DA69_RS06060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DA69_RS06095	COG0602	queuosine metabolic process
DA69_RS06145	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DA69_RS06155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DA69_RS06165	COG0343	queuine tRNA-ribosyltransferase activity
DA69_RS06175	COG2205	protein histidine kinase activity
DA69_RS06175	COG0784	Response regulator, receiver
DA69_RS06180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DA69_RS06190	COG5002	protein histidine kinase activity
DA69_RS06220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DA69_RS06235	COG0525	valine-tRNA ligase activity
DA69_RS06245	COG1228	amidohydrolase
DA69_RS06250	COG0010	Belongs to the arginase family
DA69_RS06255	COG2188	Transcriptional regulator
DA69_RS06260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DA69_RS06265	COG2986	histidine ammonia-lyase
DA69_RS06280	COG1304	FMN binding
DA69_RS06290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DA69_RS06340	COG2363	Small membrane protein
DA69_RS06355	COG0772	Belongs to the SEDS family
DA69_RS06360	COG0768	penicillin binding
DA69_RS06380	COG0625	glutathione transferase activity
DA69_RS06400	COG0142	geranyltranstransferase activity
DA69_RS06435	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DA69_RS06440	COG1024	Enoyl-CoA hydratase
DA69_RS06450	COG0113	porphobilinogen synthase activity
DA69_RS06460	COG1360	Flagellar Motor Protein
DA69_RS06465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DA69_RS06470	COG0501	Belongs to the peptidase M48B family
DA69_RS06475	COG1704	LemA family
DA69_RS06480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DA69_RS06485	COG1381	Involved in DNA repair and RecF pathway recombination
DA69_RS06500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DA69_RS06515	COG0681	Belongs to the peptidase S26 family
DA69_RS06520	COG0736	holo-[acyl-carrier-protein] synthase activity
DA69_RS06535	COG1611	Belongs to the LOG family
DA69_RS06545	COG1758	RNA polymerase activity
DA69_RS06550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DA69_RS06560	COG1573	uracil-dna glycosylase
DA69_RS06570	COG1530	ribonuclease E activity
DA69_RS06595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DA69_RS06605	COG0439	Biotin carboxylase
DA69_RS06610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DA69_RS06625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DA69_RS06640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DA69_RS06650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DA69_RS06660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DA69_RS06665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DA69_RS06675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DA69_RS06680	COG3590	peptidase
DA69_RS06695	COG0488	(ABC) transporter
DA69_RS06725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DA69_RS06750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DA69_RS06755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DA69_RS06760	COG0436	Aminotransferase
DA69_RS06765	COG1376	ErfK ybiS ycfS ynhG family protein
DA69_RS06770	COG0590	tRNA wobble adenosine to inosine editing
DA69_RS06775	COG0194	GDP metabolic process
DA69_RS06780	COG1561	YicC-like family, N-terminal region
DA69_RS06785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DA69_RS06790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DA69_RS06795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA69_RS06805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DA69_RS06810	COG0360	Binds together with S18 to 16S ribosomal RNA
DA69_RS06815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DA69_RS06820	COG0359	binds to the 23S rRNA
DA69_RS06840	COG0305	Participates in initiation and elongation during chromosome replication
DA69_RS06845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DA69_RS06865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DA69_RS06875	COG4221	oxidoreductase activity
DA69_RS06885	COG1160	GTP binding
DA69_RS06905	COG1595	DNA-templated transcription, initiation
DA69_RS06920	COG1393	Belongs to the ArsC family
DA69_RS06945	COG1012	belongs to the aldehyde dehydrogenase family
DA69_RS06950	COG3724	N-succinylarginine dihydrolase activity
DA69_RS06955	COG3186	Phenylalanine-4-hydroxylase
DA69_RS06960	COG0248	Ppx GppA phosphatase
DA69_RS06985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DA69_RS06990	COG2032	superoxide dismutase activity
DA69_RS07000	COG0629	single-stranded DNA binding
DA69_RS07015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA69_RS07020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DA69_RS07030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DA69_RS07065	COG3021	interspecies interaction between organisms
DA69_RS07070	COG0617	tRNA 3'-terminal CCA addition
DA69_RS07075	COG0494	nUDIX hydrolase
DA69_RS07090	COG1024	Enoyl-CoA hydratase
DA69_RS07125	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA69_RS07180	COG0012	GTP binding
DA69_RS07185	COG2873	o-acetylhomoserine
DA69_RS07200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DA69_RS07200	COG2857	Cytochrome c1
DA69_RS07205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DA69_RS07210	COG0723	plastoquinol--plastocyanin reductase activity
DA69_RS07215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DA69_RS07225	COG0408	coproporphyrinogen oxidase activity
DA69_RS07235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DA69_RS07235	COG0519	Catalyzes the synthesis of GMP from XMP
DA69_RS07245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DA69_RS07255	COG1063	alcohol dehydrogenase
DA69_RS07270	COG0156	8-amino-7-oxononanoate synthase activity
DA69_RS07290	COG0346	lactoylglutathione lyase activity
DA69_RS07305	COG4770	biotin carboxylase activity
DA69_RS07310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DA69_RS07315	COG1396	sequence-specific DNA binding
DA69_RS07315	COG3800	Transcriptional regulator
DA69_RS07340	COG2205	protein histidine kinase activity
DA69_RS07365	COG4795	General secretion pathway protein
DA69_RS07380	COG2165	general secretion pathway protein
DA69_RS07415	COG0531	amino acid
DA69_RS07425	COG0203	ribosomal protein L17
DA69_RS07455	COG0201	protein transport
DA69_RS07460	COG0200	Binds to the 23S rRNA
DA69_RS07465	COG1841	ribosomal large subunit assembly
DA69_RS07475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DA69_RS07485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DA69_RS07490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DA69_RS07505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DA69_RS07510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DA69_RS07515	COG0255	Belongs to the universal ribosomal protein uL29 family
DA69_RS07520	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DA69_RS07525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DA69_RS07530	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DA69_RS07535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DA69_RS07540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DA69_RS07545	COG0089	rRNA binding
DA69_RS07555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DA69_RS07560	COG0051	transcription antitermination factor activity, RNA binding
DA69_RS07585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DA69_RS07595	COG0049	tRNA binding
DA69_RS07600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DA69_RS07610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DA69_RS07615	COG0085	RNA polymerase activity
DA69_RS07625	COG0545	Peptidyl-prolyl cis-trans isomerase
DA69_RS07640	COG0222	ribosome binding
DA69_RS07645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DA69_RS07655	COG0306	phosphate transporter
DA69_RS07660	COG1392	Phosphate transport regulator
DA69_RS07665	COG0081	regulation of translation
DA69_RS07670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DA69_RS07680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DA69_RS07700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA69_RS07715	COG1294	oxidase, subunit
DA69_RS07725	COG4988	ABC transporter
DA69_RS07730	COG1132	(ABC) transporter
DA69_RS07740	COG1253	flavin adenine dinucleotide binding
DA69_RS07745	COG2205	protein histidine kinase activity
DA69_RS07745	COG0784	Response regulator, receiver
DA69_RS07750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DA69_RS07765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DA69_RS07770	COG0861	Integral membrane protein TerC family
DA69_RS07775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA69_RS07780	COG0534	Mate efflux family protein
DA69_RS07790	COG4770	biotin carboxylase activity
DA69_RS07795	COG1024	Enoyl-CoA hydratase
DA69_RS07805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DA69_RS07820	COG0501	Belongs to the peptidase M48B family
DA69_RS07830	COG0848	biopolymer transport protein
DA69_RS07850	COG0424	maF-like protein
DA69_RS07855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DA69_RS07860	COG5328	Belongs to the UPF0262 family
DA69_RS07885	COG0402	S-adenosylhomocysteine deaminase activity
DA69_RS07890	COG0586	Pfam SNARE associated Golgi protein
DA69_RS07915	COG0321	lipoyl(octanoyl) transferase activity
DA69_RS07930	COG2239	Acts as a magnesium transporter
DA69_RS07940	COG1960	acyl-CoA dehydrogenase activity
DA69_RS07960	COG5442	Flagellar protein FlaF
DA69_RS07980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA69_RS07990	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DA69_RS08015	COG1012	belongs to the aldehyde dehydrogenase family
DA69_RS08025	COG0473	3-isopropylmalate dehydrogenase activity
DA69_RS08040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DA69_RS08045	COG4771	TonB-dependent receptor
DA69_RS08050	COG3540	Alkaline phosphatase
DA69_RS08065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA69_RS08075	COG3191	aminopeptidase activity
DA69_RS08080	COG0405	Gamma-glutamyltransferase
DA69_RS08090	COG1473	amidohydrolase
DA69_RS08115	COG0531	amino acid
DA69_RS08130	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DA69_RS08145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DA69_RS08150	COG1845	cytochrome c oxidase, subunit III
DA69_RS08155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DA69_RS08160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DA69_RS08165	COG0477	Major facilitator Superfamily
DA69_RS08215	COG0583	DNA-binding transcription factor activity
DA69_RS08230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DA69_RS08245	COG1127	ABC transporter
DA69_RS08250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DA69_RS08275	COG1749	Flagellar hook protein flgE
DA69_RS08285	COG0482	sulfurtransferase activity
DA69_RS08305	COG4574	serine-type endopeptidase inhibitor activity
DA69_RS08320	COG2205	protein histidine kinase activity
DA69_RS08325	COG0352	thiamine-phosphate diphosphorylase activity
DA69_RS08335	COG2193	ferroxidase activity
DA69_RS08345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DA69_RS08350	COG0483	inositol monophosphate 1-phosphatase activity
DA69_RS08355	COG0584	glycerophosphoryl diester phosphodiesterase
DA69_RS08360	COG1132	(ABC) transporter
DA69_RS08365	COG0254	rRNA binding
DA69_RS08370	COG2989	Protein conserved in bacteria
DA69_RS08385	COG3321	synthase
DA69_RS08385	COG0604	alcohol dehydrogenase
DA69_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS08405	COG0163	prenyltransferase activity
DA69_RS08430	COG4206	TonB-dependent receptor
DA69_RS08435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DA69_RS08440	COG0531	amino acid
DA69_RS08445	COG3447	MASE1 domain protein
DA69_RS08445	COG5002	protein histidine kinase activity
DA69_RS08445	COG5001	Diguanylate cyclase
DA69_RS08450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DA69_RS08455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DA69_RS08465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DA69_RS08475	COG4152	abc transporter atp-binding protein
DA69_RS08480	COG0741	lytic transglycosylase activity
DA69_RS08480	COG1196	nuclear chromosome segregation
DA69_RS08480	COG0739	heme binding
DA69_RS08485	COG3240	lipase activity
DA69_RS08490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DA69_RS08505	COG0745	RESPONSE REGULATOR receiver
DA69_RS08525	COG0573	inorganic phosphate transmembrane transporter activity
DA69_RS08530	COG5002	protein histidine kinase activity
DA69_RS08535	COG0784	Response regulator, receiver
DA69_RS08535	COG2198	Histidine kinase
DA69_RS08535	COG2205	protein histidine kinase activity
DA69_RS08545	COG2224	Isocitrate lyase
DA69_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS08685	COG0215	cysteine-tRNA ligase activity
DA69_RS08690	COG0302	gtp cyclohydrolase
DA69_RS08695	COG0848	biopolymer transport protein
DA69_RS08710	COG0656	L-ascorbic acid biosynthetic process
DA69_RS08720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DA69_RS08735	COG0312	modulator of DNA gyrase
DA69_RS08740	COG0483	inositol monophosphate 1-phosphatase activity
DA69_RS08760	COG1132	(ABC) transporter
DA69_RS08765	COG2121	Domain of unknown function (DUF374)
DA69_RS08770	COG1519	Transferase
DA69_RS08790	COG0151	Belongs to the GarS family
DA69_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS08830	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DA69_RS08835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DA69_RS08850	COG0196	riboflavin kinase activity
DA69_RS08855	COG2030	dehydratase
DA69_RS08865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DA69_RS08875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DA69_RS08885	COG0018	arginyl-trna synthetase
DA69_RS08895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DA69_RS08900	COG1335	isochorismatase
DA69_RS08905	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DA69_RS08910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DA69_RS08915	COG0509	glycine decarboxylation via glycine cleavage system
DA69_RS08925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DA69_RS08940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DA69_RS08945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DA69_RS08950	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DA69_RS08955	COG0356	it plays a direct role in the translocation of protons across the membrane
DA69_RS08965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DA69_RS08970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DA69_RS08975	COG1472	Belongs to the glycosyl hydrolase 3 family
DA69_RS08985	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DA69_RS08990	COG0316	Belongs to the HesB IscA family
DA69_RS08995	COG0693	protein deglycase activity
DA69_RS09005	COG2321	neutral zinc metallopeptidase
DA69_RS09030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DA69_RS09045	COG0626	cystathionine gamma-synthase activity
DA69_RS09050	COG0840	transmembrane signaling receptor activity
DA69_RS09055	COG0730	response to heat
DA69_RS09060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DA69_RS09065	COG0745	RESPONSE REGULATOR receiver
DA69_RS09075	COG4771	TonB-dependent receptor
DA69_RS09085	COG0625	glutathione transferase activity
DA69_RS09150	COG0010	Belongs to the arginase family
DA69_RS09205	COG4221	oxidoreductase activity
DA69_RS09225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DA69_RS09240	COG5006	permease, DMT superfamily
DA69_RS09295	COG2166	iron-sulfur cluster assembly
DA69_RS09300	COG2205	protein histidine kinase activity
DA69_RS09325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DA69_RS09330	COG2364	Membrane
DA69_RS09355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DA69_RS09370	COG3300	MHYT domain
DA69_RS09370	COG5001	Diguanylate cyclase
DA69_RS09380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DA69_RS09385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DA69_RS09400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DA69_RS09405	COG1684	flagellar biosynthetic protein fliR
DA69_RS09410	COG1987	bacterial-type flagellum assembly
DA69_RS09415	COG0302	gtp cyclohydrolase
DA69_RS09430	COG1677	Flagellar hook-basal body complex protein FliE
DA69_RS09435	COG1558	bacterial-type flagellum-dependent cell motility
DA69_RS09445	COG3190	flagellar
DA69_RS09450	COG1338	Plays a role in the flagellum-specific transport system
DA69_RS09455	COG0776	regulation of translation
DA69_RS09470	COG4771	TonB-dependent receptor
DA69_RS09485	COG2197	response regulator
DA69_RS09500	COG2885	chlorophyll binding
DA69_RS09505	COG0789	Transcriptional regulator
DA69_RS09525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DA69_RS09535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DA69_RS09550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DA69_RS09575	COG2860	membrane
DA69_RS09590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DA69_RS09595	COG1278	Cold shock
DA69_RS09605	COG2326	polyphosphate kinase activity
DA69_RS09615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DA69_RS09625	COG1476	TRANSCRIPTIONal
DA69_RS09640	COG2264	protein methyltransferase activity
DA69_RS09650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DA69_RS09655	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DA69_RS09665	COG2202	Pas domain
DA69_RS09665	COG2205	protein histidine kinase activity
DA69_RS09680	COG1595	DNA-templated transcription, initiation
DA69_RS09690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DA69_RS09695	COG2205	protein histidine kinase activity
DA69_RS09710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA69_RS09715	COG3088	subunit of a heme lyase
DA69_RS09720	COG1138	Cytochrome C-type biogenesis protein
DA69_RS09765	COG0351	phosphomethylpyrimidine kinase
DA69_RS09770	COG2076	Multidrug Resistance protein
DA69_RS09780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DA69_RS09795	COG0037	tRNA processing
DA69_RS09810	COG2885	chlorophyll binding
DA69_RS09815	COG0823	Involved in the tonB-independent uptake of proteins
DA69_RS09835	COG0824	Thioesterase
DA69_RS09845	COG2255	four-way junction helicase activity
DA69_RS09850	COG0632	four-way junction helicase activity
DA69_RS09855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DA69_RS09860	COG1285	pathogenesis
DA69_RS09880	COG0217	transcriptional regulatory protein
DA69_RS09890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA69_RS09905	COG1388	LysM domain
DA69_RS09905	COG3584	3D domain protein
DA69_RS09915	COG0513	Belongs to the DEAD box helicase family
DA69_RS09920	COG1733	regulation of RNA biosynthetic process
DA69_RS09940	COG5507	3-demethylubiquinone-9 3-methyltransferase
DA69_RS09945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DA69_RS09950	COG0358	DNA primase activity
DA69_RS09970	COG0505	Belongs to the CarA family
DA69_RS09975	COG0531	amino acid
DA69_RS09985	COG1011	Hydrolase
DA69_RS09990	COG4771	TonB-dependent receptor
DA69_RS10000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DA69_RS10025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DA69_RS10040	COG0492	ferredoxin-NADP+ reductase activity
DA69_RS10080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DA69_RS10095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DA69_RS10100	COG0288	reversible hydration of carbon dioxide
DA69_RS10105	COG0322	excinuclease ABC activity
DA69_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
DA69_RS10160	COG1823	symporter activity
DA69_RS10180	COG0556	nucleotide-excision repair
DA69_RS10215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DA69_RS10225	COG4990	cell redox homeostasis
DA69_RS10225	COG3591	Belongs to the peptidase S1B family
DA69_RS10240	COG0577	efflux transmembrane transporter activity
DA69_RS10240	COG1136	(ABC) transporter
DA69_RS10250	COG1024	Enoyl-CoA hydratase
DA69_RS10265	COG1619	proteins homologs of microcin C7 resistance protein MccF
DA69_RS10270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DA69_RS10275	COG5002	protein histidine kinase activity
DA69_RS10275	COG0784	Response regulator, receiver
DA69_RS10280	COG3128	pkhd-type hydroxylase
DA69_RS10285	COG4774	siderophore transport
DA69_RS10295	COG2852	Protein conserved in bacteria
DA69_RS10305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DA69_RS10320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DA69_RS10325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DA69_RS10330	COG0107	imidazoleglycerol-phosphate synthase activity
DA69_RS10340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DA69_RS10345	COG0363	glucosamine-6-phosphate deaminase activity
DA69_RS10365	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DA69_RS10450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DA69_RS10470	COG0612	Peptidase, M16
DA69_RS10490	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DA69_RS10505	COG1968	undecaprenyl-diphosphatase activity
DA69_RS10510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA69_RS10515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DA69_RS10530	COG2814	Major facilitator Superfamily
DA69_RS10595	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DA69_RS10600	COG0545	Peptidyl-prolyl cis-trans isomerase
DA69_RS10605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DA69_RS10625	COG3391	amine dehydrogenase activity
DA69_RS10645	COG1607	acyl-coa hydrolase
DA69_RS10665	COG0101	tRNA pseudouridine synthase activity
DA69_RS10690	COG0336	Belongs to the RNA methyltransferase TrmD family
DA69_RS10695	COG0335	large ribosomal subunit rRNA binding
DA69_RS10705	COG3483	tryptophan 2,3-dioxygenase activity
DA69_RS10750	COG1196	nuclear chromosome segregation
DA69_RS10750	COG0741	lytic transglycosylase activity
DA69_RS10750	COG0739	heme binding
DA69_RS10775	COG1476	TRANSCRIPTIONal
DA69_RS10785	COG1322	Protein conserved in bacteria
DA69_RS10790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DA69_RS10795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DA69_RS10800	COG0778	Nitroreductase
DA69_RS10825	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DA69_RS10830	COG3474	cytochrome
DA69_RS10840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DA69_RS10855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DA69_RS10860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DA69_RS10865	COG1671	Belongs to the UPF0178 family
DA69_RS10880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DA69_RS10890	COG2154	pterin-4-alpha-carbinolamine dehydratase
DA69_RS10905	COG1228	amidohydrolase
DA69_RS10920	COG2086	electron transfer activity
DA69_RS10940	COG4771	TonB-dependent receptor
DA69_RS10950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DA69_RS10955	COG0840	transmembrane signaling receptor activity
DA69_RS10960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DA69_RS10980	COG0793	Belongs to the peptidase S41A family
DA69_RS10990	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DA69_RS10995	COG0799	negative regulation of ribosome biogenesis
DA69_RS11000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DA69_RS11010	COG0346	lactoylglutathione lyase activity
DA69_RS11025	COG1131	(ABC) transporter
DA69_RS11040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DA69_RS11045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DA69_RS11050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DA69_RS11070	COG1253	flavin adenine dinucleotide binding
DA69_RS11085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DA69_RS11095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DA69_RS11100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA69_RS11150	COG2205	protein histidine kinase activity
DA69_RS11160	COG2890	protein-(glutamine-N5) methyltransferase activity
DA69_RS11165	COG1295	ribonuclease BN
DA69_RS11170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DA69_RS11180	COG0730	response to heat
DA69_RS11195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DA69_RS11210	COG0527	aspartate kinase activity
DA69_RS11230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA69_RS11235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DA69_RS11245	COG2226	methyltransferase
DA69_RS11255	COG0494	nUDIX hydrolase
DA69_RS11260	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DA69_RS11265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DA69_RS11270	COG0653	protein targeting
DA69_RS11290	COG0735	belongs to the Fur family
DA69_RS11305	COG2130	NADP-dependent
DA69_RS11315	COG0784	Response regulator, receiver
DA69_RS11340	COG0686	Belongs to the AlaDH PNT family
DA69_RS11350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA69_RS11350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA69_RS11360	COG2081	HI0933 family
DA69_RS11375	COG0745	RESPONSE REGULATOR receiver
DA69_RS11380	COG2205	protein histidine kinase activity
DA69_RS11390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DA69_RS11390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA69_RS11395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA69_RS11400	COG1320	monovalent cation:proton antiporter activity
DA69_RS11405	COG2212	antiporter activity
DA69_RS11410	COG1863	multisubunit Na H antiporter MnhE subunit
DA69_RS11415	COG0651	ATP synthesis coupled electron transport
DA69_RS11420	COG1006	Multisubunit Na H antiporter MnhC subunit
DA69_RS11425	COG2111	Na H antiporter
DA69_RS11425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DA69_RS11430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA69_RS11445	COG1802	Transcriptional regulator
DA69_RS11455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DA69_RS11460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DA69_RS11475	COG4974	Belongs to the 'phage' integrase family
DA69_RS11510	COG0129	dihydroxy-acid dehydratase activity
DA69_RS11515	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DA69_RS11530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DA69_RS11540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DA69_RS11545	COG0066	3-isopropylmalate dehydratase activity
DA69_RS11580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DA69_RS11585	COG4993	Dehydrogenase
DA69_RS11590	COG1309	transcriptional regulator
DA69_RS11595	COG3590	peptidase
DA69_RS11600	COG0124	histidyl-tRNA synthetase
DA69_RS11605	COG2311	Membrane
DA69_RS11615	COG1250	3-hydroxyacyl-CoA dehydrogenase
DA69_RS11645	COG4771	TonB-dependent receptor
DA69_RS11670	COG1218	3'(2'),5'-bisphosphate nucleotidase
DA69_RS11680	COG0271	Belongs to the BolA IbaG family
DA69_RS11690	COG2003	Belongs to the UPF0758 family
DA69_RS11695	COG0024	Methionine aminopeptidase
DA69_RS11700	COG1546	Belongs to the CinA family
DA69_RS11700	COG1058	Belongs to the CinA family
DA69_RS11735	COG0180	Tryptophanyl-tRNA synthetase
DA69_RS11740	COG0728	peptidoglycan biosynthetic process
DA69_RS11750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DA69_RS11800	COG2885	chlorophyll binding
DA69_RS11805	COG4232	protein-disulfide reductase activity
DA69_RS11820	COG0166	Belongs to the GPI family
DA69_RS11835	COG0459	protein refolding
DA69_RS11840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DA69_RS11845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DA69_RS11855	COG2234	aminopeptidase activity
DA69_RS11870	COG2962	Rard protein
DA69_RS11875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DA69_RS11880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DA69_RS11915	COG0633	Ferredoxin
DA69_RS11930	COG2205	protein histidine kinase activity
DA69_RS11945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DA69_RS11945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DA69_RS11960	COG1505	serine-type exopeptidase activity
DA69_RS11965	COG1505	serine-type exopeptidase activity
DA69_RS11970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DA69_RS11975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DA69_RS11980	COG0280	phosphate acetyltransferase
DA69_RS11980	COG0281	malic enzyme
DA69_RS11985	COG2211	Major facilitator Superfamily
DA69_RS11995	COG0606	chelatase, subunit chli
DA69_RS12000	COG0189	ligase activity
DA69_RS12015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DA69_RS12020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DA69_RS12025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DA69_RS12035	COG3655	Transcriptional regulator
DA69_RS12045	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DA69_RS12050	COG4133	protoheme IX ABC transporter activity
DA69_RS12055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DA69_RS12065	COG0450	alkyl hydroperoxide reductase
DA69_RS12070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DA69_RS12075	COG1396	sequence-specific DNA binding
DA69_RS12080	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DA69_RS12085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DA69_RS12090	COG1702	phosphate starvation-inducible protein PhoH
DA69_RS12095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DA69_RS12105	COG0456	acetyltransferase
DA69_RS12115	COG1396	sequence-specific DNA binding
DA69_RS12125	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DA69_RS12140	COG1280	lysine exporter protein (LysE YggA)
DA69_RS12160	COG3118	belongs to the thioredoxin family
DA69_RS12165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DA69_RS12175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DA69_RS12180	COG1674	ftsk spoiiie
DA69_RS12185	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DA69_RS12195	COG0471	metal ion transport
DA69_RS12195	COG0490	domain, Protein
DA69_RS12210	COG0745	RESPONSE REGULATOR receiver
DA69_RS12235	COG0495	leucyl-tRNA aminoacylation
DA69_RS12285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DA69_RS12290	COG1981	membrane
DA69_RS12295	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DA69_RS12305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DA69_RS12310	COG0424	maF-like protein
DA69_RS12315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DA69_RS12320	COG0237	dephospho-CoA kinase activity
DA69_RS12325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DA69_RS12330	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DA69_RS12335	COG4395	Tim44
DA69_RS12350	COG0433	COG0433 Predicted ATPase
DA69_RS12360	COG2902	Dehydrogenase
DA69_RS12380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DA69_RS12385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DA69_RS12405	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DA69_RS12425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DA69_RS12430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DA69_RS12470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DA69_RS12480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA69_RS12485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DA69_RS12495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA69_RS12510	COG2917	probably involved in intracellular septation
DA69_RS12515	COG0552	protein localization to endoplasmic reticulum
DA69_RS12530	COG2824	Alkylphosphonate utilization operon protein PhnA
DA69_RS12535	COG0596	Alpha beta hydrolase
DA69_RS12540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DA69_RS12570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DA69_RS12575	COG1959	2 iron, 2 sulfur cluster binding
DA69_RS12580	COG0300	oxidoreductase activity
DA69_RS12585	COG2095	MarC family integral membrane protein
DA69_RS12600	COG5508	conserved small protein
DA69_RS12605	COG0501	Belongs to the peptidase M48B family
DA69_RS12620	COG0779	Required for maturation of 30S ribosomal subunits
DA69_RS12635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DA69_RS12640	COG4106	trans-aconitate 2-methyltransferase activity
DA69_RS12660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DA69_RS12670	COG1185	polyribonucleotide nucleotidyltransferase activity
DA69_RS12695	COG0412	Dienelactone hydrolase
DA69_RS12705	COG0443	Heat shock 70 kDa protein
DA69_RS12710	COG0484	heat shock protein binding
DA69_RS12715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DA69_RS12725	COG0756	dUTP diphosphatase activity
DA69_RS12730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DA69_RS12740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DA69_RS12750	COG0598	Magnesium transport protein CorA
DA69_RS12760	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DA69_RS12765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DA69_RS12770	COG0228	four-way junction DNA binding
DA69_RS12775	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DA69_RS12780	COG0625	glutathione transferase activity
DA69_RS12790	COG3135	benzoate transporter
DA69_RS12795	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DA69_RS12805	COG0670	Belongs to the BI1 family
DA69_RS12815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA69_RS12835	COG1999	signal sequence binding
DA69_RS12850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DA69_RS12855	COG4106	trans-aconitate 2-methyltransferase activity
DA69_RS12860	COG0596	Alpha beta hydrolase
DA69_RS12875	COG0513	Belongs to the DEAD box helicase family
DA69_RS12880	COG0138	bifunctional purine biosynthesis protein purh
DA69_RS12900	COG0598	Magnesium transport protein CorA
DA69_RS12910	COG4771	TonB-dependent receptor
DA69_RS12915	COG2814	Major facilitator Superfamily
DA69_RS12920	COG0045	succinate-CoA ligase (ADP-forming) activity
DA69_RS12925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DA69_RS12935	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA69_RS12950	COG1960	acyl-CoA dehydrogenase activity
DA69_RS12955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA69_RS12990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DA69_RS12995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DA69_RS13000	COG0596	Alpha beta hydrolase
DA69_RS13005	COG0859	PFAM glycosyl transferase family 9
DA69_RS13010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DA69_RS13020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DA69_RS13025	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DA69_RS13030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DA69_RS13045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA69_RS13045	COG0072	phenylalanine-tRNA ligase activity
DA69_RS13065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DA69_RS13070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DA69_RS13075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DA69_RS13090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DA69_RS13095	COG0588	phosphoglycerate mutase activity
DA69_RS13100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DA69_RS13100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DA69_RS13110	COG0071	Belongs to the small heat shock protein (HSP20) family
DA69_RS13140	COG2261	transglycosylase associated protein
DA69_RS13150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DA69_RS13150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DA69_RS13155	COG1217	gtp-binding protein TYPA
DA69_RS13170	COG1297	OPT oligopeptide transporter protein
DA69_RS13175	COG0514	ATP-dependent DNA helicase (RecQ)
DA69_RS13180	COG0596	Alpha beta hydrolase
DA69_RS13190	COG3706	GGDEF domain
DA69_RS13215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DA69_RS13220	COG0268	Binds directly to 16S ribosomal RNA
DA69_RS13235	COG2813	Specifically methylates the guanine in position
DA69_RS13240	COG1187	pseudouridine synthase activity
DA69_RS13245	COG0135	phosphoribosylanthranilate isomerase activity
DA69_RS13250	COG0133	tryptophan synthase activity
DA69_RS13260	COG0159	tryptophan synthase activity
DA69_RS13280	COG1074	ATP-dependent DNA helicase activity
DA69_RS13285	COG2887	Belongs to the helicase family. UvrD subfamily
DA69_RS13290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DA69_RS13295	COG3178	'Phosphotransferase
DA69_RS13300	COG0802	atpase or kinase
DA69_RS13310	COG1506	peptidase
DA69_RS13310	COG0823	Involved in the tonB-independent uptake of proteins
DA69_RS13325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DA69_RS13375	COG4964	Belongs to the GSP D family
DA69_RS13410	COG0251	oxidation-reduction process
DA69_RS13420	COG2351	hydroxyisourate hydrolase activity
DA69_RS13450	COG0842	Transport permease protein
DA69_RS13460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DA69_RS13465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DA69_RS13485	COG0730	response to heat
DA69_RS13495	COG1250	3-hydroxyacyl-CoA dehydrogenase
DA69_RS13495	COG1024	Enoyl-CoA hydratase
DA69_RS13500	COG0183	Belongs to the thiolase family
DA69_RS13505	COG2133	pyrroloquinoline quinone binding
DA69_RS13515	COG1278	Cold shock
DA69_RS13525	COG1971	Probably functions as a manganese efflux pump
DA69_RS13530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DA69_RS13550	COG0612	Peptidase, M16
DA69_RS13560	COG0542	response to heat
DA69_RS13575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA69_RS13580	COG0165	Argininosuccinate lyase
DA69_RS13590	COG0019	diaminopimelate decarboxylase activity
DA69_RS13595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DA69_RS13605	COG2884	Cell division ATP-binding protein ftsE
DA69_RS13620	COG0204	Acyl-transferase
DA69_RS13630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DA69_RS13645	COG1199	ATP-dependent helicase activity
DA69_RS13650	COG1201	RNA secondary structure unwinding
DA69_RS13660	COG1522	sequence-specific DNA binding
DA69_RS13705	COG0405	Gamma-glutamyltransferase
DA69_RS13720	COG0671	phosphoesterase, PA-phosphatase related
DA69_RS13725	COG0427	acetyl-CoA hydrolase
DA69_RS13730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DA69_RS13730	COG1372	Participates in initiation and elongation during chromosome replication
DA69_RS13740	COG4191	Histidine kinase
DA69_RS13750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DA69_RS13760	COG0706	membrane insertase activity
DA69_RS13775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA69_RS13790	COG1596	polysaccharide export
DA69_RS13800	COG0517	IMP dehydrogenase activity
DA69_RS13800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DA69_RS13805	COG1877	trehalose-phosphatase activity
DA69_RS13815	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DA69_RS13825	COG2885	chlorophyll binding
DA69_RS13825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DA69_RS13840	COG2957	Belongs to the agmatine deiminase family
DA69_RS13875	COG1899	peptidyl-lysine modification to peptidyl-hypusine
DA69_RS13880	COG1166	arginine decarboxylase activity
DA69_RS13885	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DA69_RS13890	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DA69_RS13895	COG3639	organic phosphonate transmembrane transporter activity
DA69_RS13900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DA69_RS13915	COG0438	transferase activity, transferring glycosyl groups
DA69_RS13920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DA69_RS13920	COG0506	proline dehydrogenase activity
DA69_RS13920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DA69_RS13945	COG0463	Glycosyl transferase, family 2
DA69_RS13955	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DA69_RS13960	COG1272	protein, Hemolysin III
DA69_RS13970	COG1404	Belongs to the peptidase S8 family
DA69_RS13975	COG2171	N-acyltransferase activity
DA69_RS13995	COG2942	2-epimerase
DA69_RS14035	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DA69_RS14055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DA69_RS14080	COG1450	Type ii and iii secretion system protein
DA69_RS14125	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity