locus-tag	class	description
BSP_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSP_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSP_RS00040	COG3511	phospholipase C
BSP_RS00045	COG2188	Transcriptional regulator
BSP_RS00050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSP_RS00055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSP_RS00065	COG0513	Belongs to the DEAD box helicase family
BSP_RS00075	COG0024	Methionine aminopeptidase
BSP_RS00085	COG2003	Belongs to the UPF0758 family
BSP_RS00090	COG1446	asparaginase
BSP_RS00100	COG0271	Belongs to the BolA IbaG family
BSP_RS00110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSP_RS00125	COG1902	pentaerythritol trinitrate reductase activity
BSP_RS00135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSP_RS00145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSP_RS00180	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSP_RS00200	COG2885	chlorophyll binding
BSP_RS00235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSP_RS00235	COG0475	glutathione-regulated potassium exporter activity
BSP_RS00240	COG2304	oxidoreductase activity
BSP_RS00255	COG2205	protein histidine kinase activity
BSP_RS00255	COG2202	Pas domain
BSP_RS00260	COG0659	secondary active sulfate transmembrane transporter activity
BSP_RS00265	COG0183	Belongs to the thiolase family
BSP_RS00280	COG1477	protein flavinylation
BSP_RS00305	COG3128	pkhd-type hydroxylase
BSP_RS00310	COG4774	siderophore transport
BSP_RS00330	COG2308	Evidence 4 Homologs of previously reported genes of
BSP_RS00345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSP_RS00350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSP_RS00360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSP_RS00365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSP_RS00370	COG0107	imidazoleglycerol-phosphate synthase activity
BSP_RS00380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSP_RS00385	COG0363	glucosamine-6-phosphate deaminase activity
BSP_RS00395	COG0837	glucose binding
BSP_RS00460	COG1002	Type II restriction enzyme, methylase subunits
BSP_RS00470	COG1061	Type III restriction enzyme res subunit
BSP_RS00475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSP_RS00485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSP_RS00515	COG0351	phosphomethylpyrimidine kinase
BSP_RS00525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSP_RS00545	COG3474	cytochrome
BSP_RS00550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSP_RS00555	COG2816	NAD+ diphosphatase activity
BSP_RS00575	COG0302	gtp cyclohydrolase
BSP_RS00580	COG3645	SOS response
BSP_RS00585	COG1987	bacterial-type flagellum assembly
BSP_RS00590	COG1684	flagellar biosynthetic protein fliR
BSP_RS00595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSP_RS00610	COG0745	RESPONSE REGULATOR receiver
BSP_RS00620	COG1218	3'(2'),5'-bisphosphate nucleotidase
BSP_RS00645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSP_RS00650	COG4106	trans-aconitate 2-methyltransferase activity
BSP_RS00655	COG2267	carboxylic ester hydrolase activity
BSP_RS00665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSP_RS00680	COG1846	Transcriptional regulator
BSP_RS00685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSP_RS00735	COG2917	probably involved in intracellular septation
BSP_RS00740	COG0552	protein localization to endoplasmic reticulum
BSP_RS00750	COG0024	Methionine aminopeptidase
BSP_RS00760	COG2824	Alkylphosphonate utilization operon protein PhnA
BSP_RS00765	COG0523	cobalamin synthesis protein
BSP_RS00790	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSP_RS00795	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BSP_RS00800	COG3639	organic phosphonate transmembrane transporter activity
BSP_RS00805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSP_RS00810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSP_RS00815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSP_RS00820	COG3135	benzoate transporter
BSP_RS00825	COG0625	glutathione transferase activity
BSP_RS00830	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSP_RS00835	COG0228	four-way junction DNA binding
BSP_RS00840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSP_RS00845	COG0793	Belongs to the peptidase S41A family
BSP_RS00855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSP_RS00860	COG0799	negative regulation of ribosome biogenesis
BSP_RS00865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSP_RS00875	COG0735	belongs to the Fur family
BSP_RS00880	COG4771	TonB-dependent receptor
BSP_RS00895	COG2130	NADP-dependent
BSP_RS00905	COG0784	Response regulator, receiver
BSP_RS00930	COG1012	belongs to the aldehyde dehydrogenase family
BSP_RS00935	COG1522	sequence-specific DNA binding
BSP_RS00940	COG0686	Belongs to the AlaDH PNT family
BSP_RS00965	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSP_RS00965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSP_RS01005	COG0071	Belongs to the small heat shock protein (HSP20) family
BSP_RS01015	COG2861	carbohydrate metabolic process
BSP_RS01020	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BSP_RS01030	COG0598	Magnesium transport protein CorA
BSP_RS01035	COG0339	signal peptide processing
BSP_RS01040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSP_RS01055	COG0019	diaminopimelate decarboxylase activity
BSP_RS01065	COG0165	Argininosuccinate lyase
BSP_RS01070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSP_RS01360	COG4957	zinc ion binding
BSP_RS01415	COG2133	pyrroloquinoline quinone binding
BSP_RS01425	COG0183	Belongs to the thiolase family
BSP_RS01430	COG1024	Enoyl-CoA hydratase
BSP_RS01430	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSP_RS01465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSP_RS01470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSP_RS01470	COG0072	phenylalanine-tRNA ligase activity
BSP_RS01490	COG5002	protein histidine kinase activity
BSP_RS01490	COG0784	Response regulator, receiver
BSP_RS01495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSP_RS01500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSP_RS01520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSP_RS01525	COG0859	PFAM glycosyl transferase family 9
BSP_RS01535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSP_RS01555	COG2885	chlorophyll binding
BSP_RS01555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BSP_RS01560	COG0183	Belongs to the thiolase family
BSP_RS01565	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BSP_RS01580	COG3932	Exopolysaccharide synthesis, ExoD
BSP_RS01600	COG1446	asparaginase
BSP_RS01630	COG3546	catalase activity
BSP_RS01645	COG2982	Protein involved in outer membrane biogenesis
BSP_RS01655	COG0823	Involved in the tonB-independent uptake of proteins
BSP_RS01655	COG1506	peptidase
BSP_RS01665	COG3744	PilT protein domain protein
BSP_RS01675	COG0802	atpase or kinase
BSP_RS01680	COG3178	'Phosphotransferase
BSP_RS01685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSP_RS01695	COG1074	ATP-dependent DNA helicase activity
BSP_RS01710	COG0285	dihydrofolate synthase activity
BSP_RS01720	COG0159	tryptophan synthase activity
BSP_RS01730	COG0133	tryptophan synthase activity
BSP_RS01735	COG0135	phosphoribosylanthranilate isomerase activity
BSP_RS01750	COG1187	pseudouridine synthase activity
BSP_RS01755	COG2813	Specifically methylates the guanine in position
BSP_RS01790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSP_RS01795	COG0545	Peptidyl-prolyl cis-trans isomerase
BSP_RS01800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSP_RS01825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSP_RS01830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSP_RS01835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BSP_RS01845	COG2884	Cell division ATP-binding protein ftsE
BSP_RS01860	COG0204	Acyl-transferase
BSP_RS01870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSP_RS01885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSP_RS01890	COG1199	ATP-dependent helicase activity
BSP_RS01930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSP_RS01940	COG0730	response to heat
BSP_RS01960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSP_RS01970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSP_RS01980	COG0842	Transport permease protein
BSP_RS02050	COG4964	Belongs to the GSP D family
BSP_RS02090	COG2365	Tyrosine phosphatase family
BSP_RS02105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSP_RS02110	COG2814	Major facilitator Superfamily
BSP_RS02115	COG0308	aminopeptidase N
BSP_RS02130	COG0514	ATP-dependent DNA helicase (RecQ)
BSP_RS02135	COG0596	Alpha beta hydrolase
BSP_RS02140	COG1024	Enoyl-CoA hydratase
BSP_RS02155	COG1297	OPT oligopeptide transporter protein
BSP_RS02180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSP_RS02195	COG0730	response to heat
BSP_RS02200	COG1959	2 iron, 2 sulfur cluster binding
BSP_RS02210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSP_RS02225	COG0567	Dehydrogenase, E1 component
BSP_RS02230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSP_RS02250	COG0045	succinate-CoA ligase (ADP-forming) activity
BSP_RS02305	COG0741	lytic transglycosylase activity
BSP_RS02305	COG1196	nuclear chromosome segregation
BSP_RS02305	COG0739	heme binding
BSP_RS02315	COG0405	Gamma-glutamyltransferase
BSP_RS02330	COG0671	phosphoesterase, PA-phosphatase related
BSP_RS02335	COG0427	acetyl-CoA hydrolase
BSP_RS02340	COG2119	membrane
BSP_RS02345	COG0494	nUDIX hydrolase
BSP_RS02350	COG0137	argininosuccinate synthase activity
BSP_RS02355	COG0612	Peptidase, M16
BSP_RS02370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSP_RS02375	COG0494	nUDIX hydrolase
BSP_RS02385	COG2226	methyltransferase
BSP_RS02390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSP_RS02395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSP_RS02400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSP_RS02430	COG1217	gtp-binding protein TYPA
BSP_RS02440	COG0728	peptidoglycan biosynthetic process
BSP_RS02445	COG0180	Tryptophanyl-tRNA synthetase
BSP_RS02455	COG0492	ferredoxin-NADP+ reductase activity
BSP_RS02470	COG1695	Transcriptional regulator
BSP_RS02485	COG0443	Heat shock 70 kDa protein
BSP_RS02490	COG0484	heat shock protein binding
BSP_RS02495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSP_RS02515	COG0101	tRNA pseudouridine synthase activity
BSP_RS02530	COG0242	peptide deformylase activity
BSP_RS02555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSP_RS02555	COG0517	IMP dehydrogenase activity
BSP_RS02560	COG1877	trehalose-phosphatase activity
BSP_RS02570	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BSP_RS02585	COG2311	Membrane
BSP_RS02595	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSP_RS02615	COG4772	TonB-dependent receptor
BSP_RS02625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSP_RS02635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSP_RS02650	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSP_RS02655	COG2081	HI0933 family
BSP_RS02670	COG0745	RESPONSE REGULATOR receiver
BSP_RS02675	COG2205	protein histidine kinase activity
BSP_RS02685	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSP_RS02685	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSP_RS02690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSP_RS02705	COG4191	Histidine kinase
BSP_RS02705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSP_RS02710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSP_RS02715	COG0840	transmembrane signaling receptor activity
BSP_RS02720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSP_RS02725	COG4206	TonB-dependent receptor
BSP_RS02755	COG5487	UPF0391 membrane protein
BSP_RS02785	COG4232	protein-disulfide reductase activity
BSP_RS02810	COG0523	cobalamin synthesis protein
BSP_RS02825	COG0459	protein refolding
BSP_RS02830	COG0463	Glycosyl transferase, family 2
BSP_RS02860	COG1272	protein, Hemolysin III
BSP_RS02870	COG2234	aminopeptidase activity
BSP_RS02875	COG0501	Belongs to the peptidase M48B family
BSP_RS02895	COG2095	MarC family integral membrane protein
BSP_RS02905	COG2205	protein histidine kinase activity
BSP_RS02910	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSP_RS02915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSP_RS02925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSP_RS02935	COG1702	phosphate starvation-inducible protein PhoH
BSP_RS02940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSP_RS02950	COG0456	acetyltransferase
BSP_RS02960	COG1396	sequence-specific DNA binding
BSP_RS02970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSP_RS02975	COG0433	COG0433 Predicted ATPase
BSP_RS02985	COG2902	Dehydrogenase
BSP_RS03005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BSP_RS03010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSP_RS03015	COG0237	dephospho-CoA kinase activity
BSP_RS03020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSP_RS03025	COG0424	maF-like protein
BSP_RS03030	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSP_RS03035	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSP_RS03045	COG1981	membrane
BSP_RS03050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSP_RS03100	COG0495	leucyl-tRNA aminoacylation
BSP_RS03115	COG0352	thiamine-phosphate diphosphorylase activity
BSP_RS03120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSP_RS03125	COG0745	RESPONSE REGULATOR receiver
BSP_RS03135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSP_RS03150	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSP_RS03155	COG1674	ftsk spoiiie
BSP_RS03160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSP_RS03175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSP_RS03180	COG0280	phosphate acetyltransferase
BSP_RS03180	COG0281	malic enzyme
BSP_RS03185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSP_RS03195	COG1505	serine-type exopeptidase activity
BSP_RS03200	COG1505	serine-type exopeptidase activity
BSP_RS03215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSP_RS03230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BSP_RS03230	COG2885	chlorophyll binding
BSP_RS03240	COG2885	chlorophyll binding
BSP_RS03270	COG1741	Belongs to the pirin family
BSP_RS03275	COG1522	sequence-specific DNA binding
BSP_RS03300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSP_RS03305	COG0300	oxidoreductase activity
BSP_RS03310	COG1959	2 iron, 2 sulfur cluster binding
BSP_RS03320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSP_RS03320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSP_RS03335	COG0138	bifunctional purine biosynthesis protein purh
BSP_RS03340	COG0412	Dienelactone hydrolase
BSP_RS03345	COG1404	Belongs to the peptidase S8 family
BSP_RS03355	COG1420	regulation of RNA biosynthetic process
BSP_RS03380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSP_RS03405	COG0673	inositol 2-dehydrogenase activity
BSP_RS03415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BSP_RS03435	COG1940	carbohydrate kinase activity
BSP_RS03440	COG1131	(ABC) transporter
BSP_RS03450	COG0346	lactoylglutathione lyase activity
BSP_RS03460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSP_RS03460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSP_RS03475	COG2096	Adenosyltransferase
BSP_RS03480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSP_RS03500	COG0779	Required for maturation of 30S ribosomal subunits
BSP_RS03515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSP_RS03530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BSP_RS03540	COG3483	tryptophan 2,3-dioxygenase activity
BSP_RS03550	COG0335	large ribosomal subunit rRNA binding
BSP_RS03555	COG0336	Belongs to the RNA methyltransferase TrmD family
BSP_RS03565	COG2211	Major facilitator Superfamily
BSP_RS03570	COG0784	Response regulator, receiver
BSP_RS03570	COG2205	protein histidine kinase activity
BSP_RS03570	COG5002	protein histidine kinase activity
BSP_RS03575	COG0606	chelatase, subunit chli
BSP_RS03580	COG0189	ligase activity
BSP_RS03590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSP_RS03595	COG3118	belongs to the thioredoxin family
BSP_RS03600	COG1228	amidohydrolase
BSP_RS03620	COG1671	Belongs to the UPF0178 family
BSP_RS03680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSP_RS03700	COG0450	alkyl hydroperoxide reductase
BSP_RS03715	COG1872	DUF167
BSP_RS03730	COG2086	electron transfer activity
BSP_RS03755	COG1280	lysine exporter protein (LysE YggA)
BSP_RS03780	COG2198	Histidine kinase
BSP_RS03780	COG2205	protein histidine kinase activity
BSP_RS03780	COG0784	Response regulator, receiver
BSP_RS03780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSP_RS03800	COG0642	Histidine kinase
BSP_RS03805	COG0398	Pfam SNARE associated Golgi protein
BSP_RS03810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BSP_RS03820	COG0706	membrane insertase activity
BSP_RS03830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSP_RS03835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSP_RS03845	COG3655	Transcriptional regulator
BSP_RS03860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSP_RS03860	COG0475	glutathione-regulated potassium exporter activity
BSP_RS03870	COG0124	histidyl-tRNA synthetase
BSP_RS03885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSP_RS03925	COG2205	protein histidine kinase activity
BSP_RS03925	COG0784	Response regulator, receiver
BSP_RS03935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSP_RS03955	COG0633	Ferredoxin
BSP_RS03965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSP_RS03995	COG1741	Belongs to the pirin family
BSP_RS04005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSP_RS04020	COG0538	isocitrate dehydrogenase activity
BSP_RS04045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSP_RS04050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSP_RS04065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSP_RS04070	COG0438	transferase activity, transferring glycosyl groups
BSP_RS04080	COG2942	2-epimerase
BSP_RS04090	COG0506	proline dehydrogenase activity
BSP_RS04090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSP_RS04090	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSP_RS04130	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSP_RS04150	COG2171	N-acyltransferase activity
BSP_RS04155	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BSP_RS04155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSP_RS04170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSP_RS04175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSP_RS04185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSP_RS04195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSP_RS04225	COG0840	transmembrane signaling receptor activity
BSP_RS04240	COG0670	Belongs to the BI1 family
BSP_RS04250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSP_RS04275	COG0640	Transcriptional regulator
BSP_RS04330	COG3046	protein related to deoxyribodipyrimidine photolyase
BSP_RS04355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSP_RS04360	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSP_RS04365	COG4133	protoheme IX ABC transporter activity
BSP_RS04370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSP_RS04390	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSP_RS04405	COG1253	flavin adenine dinucleotide binding
BSP_RS04425	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSP_RS04430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSP_RS04435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSP_RS04445	COG2962	Rard protein
BSP_RS04450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSP_RS04455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSP_RS04470	COG0656	L-ascorbic acid biosynthetic process
BSP_RS04475	COG2267	carboxylic ester hydrolase activity
BSP_RS04485	COG2890	protein-(glutamine-N5) methyltransferase activity
BSP_RS04490	COG1295	ribonuclease BN
BSP_RS04495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSP_RS04500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSP_RS04515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSP_RS04565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSP_RS04585	COG1196	nuclear chromosome segregation
BSP_RS04585	COG3264	Mechanosensitive ion channel
BSP_RS04605	COG0643	Histidine kinase
BSP_RS04605	COG2198	Histidine kinase
BSP_RS04610	COG0835	chemotaxis
BSP_RS04620	COG0840	transmembrane signaling receptor activity
BSP_RS04625	COG0835	chemotaxis
BSP_RS04630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSP_RS04635	COG2201	protein-glutamate methylesterase activity
BSP_RS04655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSP_RS04660	COG3657	addiction module killer protein
BSP_RS04665	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSP_RS04675	COG0539	negative regulation of cytoplasmic translation
BSP_RS04695	COG3104	oligopeptide transport
BSP_RS04715	COG0312	modulator of DNA gyrase
BSP_RS04755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSP_RS04765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSP_RS04770	COG1506	peptidase
BSP_RS04800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSP_RS04805	COG1733	regulation of RNA biosynthetic process
BSP_RS04820	COG0217	transcriptional regulatory protein
BSP_RS04830	COG1285	pathogenesis
BSP_RS04840	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSP_RS04845	COG0632	four-way junction helicase activity
BSP_RS04850	COG2255	four-way junction helicase activity
BSP_RS04875	COG0824	Thioesterase
BSP_RS04915	COG0823	Involved in the tonB-independent uptake of proteins
BSP_RS04920	COG2885	chlorophyll binding
BSP_RS04935	COG0037	tRNA processing
BSP_RS04945	COG0778	Nitroreductase
BSP_RS04950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSP_RS04955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSP_RS04960	COG1322	Protein conserved in bacteria
BSP_RS04970	COG1476	TRANSCRIPTIONal
BSP_RS05015	COG1595	DNA-templated transcription, initiation
BSP_RS05055	COG2326	polyphosphate kinase activity
BSP_RS05060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSP_RS05070	COG1278	Cold shock
BSP_RS05075	COG4251	negative regulation of phosphorylation
BSP_RS05090	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSP_RS05110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSP_RS05115	COG2353	YceI-like domain
BSP_RS05130	COG4566	intracellular signal transduction
BSP_RS05135	COG4191	Histidine kinase
BSP_RS05140	COG0840	transmembrane signaling receptor activity
BSP_RS05150	COG0745	RESPONSE REGULATOR receiver
BSP_RS05155	COG0643	Histidine kinase
BSP_RS05155	COG2198	Histidine kinase
BSP_RS05160	COG0835	chemotaxis
BSP_RS05165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSP_RS05170	COG2201	protein-glutamate methylesterase activity
BSP_RS05175	COG0745	RESPONSE REGULATOR receiver
BSP_RS05180	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSP_RS05235	COG0840	transmembrane signaling receptor activity
BSP_RS05240	COG0835	chemotaxis
BSP_RS05265	COG3038	cytochrome b561
BSP_RS05280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSP_RS05280	COG2010	Cytochrome c
BSP_RS05305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSP_RS05310	COG1619	proteins homologs of microcin C7 resistance protein MccF
BSP_RS05315	COG0358	DNA primase activity
BSP_RS05325	COG1487	ribonuclease activity
BSP_RS05330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSP_RS05355	COG5507	3-demethylubiquinone-9 3-methyltransferase
BSP_RS05375	COG1733	regulation of RNA biosynthetic process
BSP_RS05380	COG0840	transmembrane signaling receptor activity
BSP_RS05405	COG3584	3D domain protein
BSP_RS05405	COG1388	LysM domain
BSP_RS05410	COG0730	response to heat
BSP_RS05420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSP_RS05425	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSP_RS05450	COG1024	Enoyl-CoA hydratase
BSP_RS05470	COG4771	TonB-dependent receptor
BSP_RS05500	COG0596	Alpha beta hydrolase
BSP_RS05505	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS05510	COG1335	isochorismatase
BSP_RS05530	COG1012	belongs to the aldehyde dehydrogenase family
BSP_RS05540	COG1349	DNA-binding transcription factor activity
BSP_RS05555	COG4191	Histidine kinase
BSP_RS05565	COG0835	chemotaxis
BSP_RS05635	COG1131	(ABC) transporter
BSP_RS05645	COG1304	FMN binding
BSP_RS05665	COG5002	protein histidine kinase activity
BSP_RS05680	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BSP_RS05685	COG1733	regulation of RNA biosynthetic process
BSP_RS05710	COG2205	protein histidine kinase activity
BSP_RS05715	COG2166	iron-sulfur cluster assembly
BSP_RS05735	COG4774	siderophore transport
BSP_RS05775	COG2205	protein histidine kinase activity
BSP_RS05790	COG3693	PFAM glycoside hydrolase, family 10
BSP_RS05810	COG5006	permease, DMT superfamily
BSP_RS05825	COG0840	transmembrane signaling receptor activity
BSP_RS05850	COG4957	zinc ion binding
BSP_RS05865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSP_RS05920	COG2076	Multidrug Resistance protein
BSP_RS05930	COG2983	Belongs to the UPF0260 family
BSP_RS05960	COG4695	Portal protein
BSP_RS06020	COG3152	Membrane
BSP_RS06045	COG0484	heat shock protein binding
BSP_RS06050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BSP_RS06055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSP_RS06075	COG0564	pseudouridine synthase activity
BSP_RS06105	COG0129	dihydroxy-acid dehydratase activity
BSP_RS06110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSP_RS06125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSP_RS06130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSP_RS06135	COG0066	3-isopropylmalate dehydratase activity
BSP_RS06140	COG0473	3-isopropylmalate dehydrogenase activity
BSP_RS06145	COG0004	ammonium transporteR
BSP_RS06160	COG2819	hydrolase of the alpha beta superfamily
BSP_RS06165	COG2190	(PTS) system
BSP_RS06165	COG2211	Major facilitator Superfamily
BSP_RS06170	COG1082	Xylose isomerase domain protein TIM barrel
BSP_RS06175	COG1609	Transcriptional regulator
BSP_RS06180	COG0366	Alpha amylase catalytic
BSP_RS06190	COG4771	TonB-dependent receptor
BSP_RS06205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSP_RS06245	COG3591	Belongs to the peptidase S1B family
BSP_RS06245	COG4990	cell redox homeostasis
BSP_RS06260	COG1136	(ABC) transporter
BSP_RS06265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSP_RS06270	COG1024	Enoyl-CoA hydratase
BSP_RS06285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSP_RS06295	COG3609	addiction module antidote protein, CC2985 family
BSP_RS06300	COG0288	reversible hydration of carbon dioxide
BSP_RS06315	COG0322	excinuclease ABC activity
BSP_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS06385	COG5383	Protein conserved in bacteria
BSP_RS06390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSP_RS06400	COG4585	Histidine kinase
BSP_RS06485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSP_RS06510	COG1472	Belongs to the glycosyl hydrolase 3 family
BSP_RS06515	COG1702	phosphate starvation-inducible protein PhoH
BSP_RS06525	COG0196	riboflavin kinase activity
BSP_RS06530	COG2030	dehydratase
BSP_RS06540	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BSP_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS06560	COG0739	heme binding
BSP_RS06560	COG0741	lytic transglycosylase activity
BSP_RS06560	COG1196	nuclear chromosome segregation
BSP_RS06570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSP_RS06570	COG4651	solute:proton antiporter activity
BSP_RS06575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSP_RS06585	COG0612	Peptidase, M16
BSP_RS06615	COG1462	curli production assembly transport component CsgG
BSP_RS06725	COG3618	amidohydrolase
BSP_RS06730	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS06735	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSP_RS06740	COG4948	Mandelate Racemase Muconate Lactonizing
BSP_RS06745	COG1414	Transcriptional regulator
BSP_RS06755	COG1304	FMN binding
BSP_RS06780	COG4677	pectinesterase activity
BSP_RS06815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSP_RS06840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSP_RS06855	COG0673	inositol 2-dehydrogenase activity
BSP_RS06860	COG0490	domain, Protein
BSP_RS06860	COG0471	metal ion transport
BSP_RS06875	COG0367	asparagine synthase
BSP_RS06880	COG0189	ligase activity
BSP_RS06880	COG2918	glutathione biosynthetic process
BSP_RS06885	COG1363	Peptidase, m42
BSP_RS06900	COG0673	inositol 2-dehydrogenase activity
BSP_RS06905	COG3800	Transcriptional regulator
BSP_RS06905	COG1396	sequence-specific DNA binding
BSP_RS06915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSP_RS06925	COG4770	biotin carboxylase activity
BSP_RS06940	COG0346	lactoylglutathione lyase activity
BSP_RS06950	COG0156	8-amino-7-oxononanoate synthase activity
BSP_RS06955	COG1063	alcohol dehydrogenase
BSP_RS06970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSP_RS06990	COG2204	response regulator
BSP_RS07065	COG3668	Plasmid stabilization system
BSP_RS07080	COG2224	Isocitrate lyase
BSP_RS07100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSP_RS07115	COG1748	Saccharopine dehydrogenase
BSP_RS07165	COG0494	nUDIX hydrolase
BSP_RS07170	COG0617	tRNA 3'-terminal CCA addition
BSP_RS07210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSP_RS07215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSP_RS07220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSP_RS07225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSP_RS07230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSP_RS07240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSP_RS07245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSP_RS07260	COG0629	single-stranded DNA binding
BSP_RS07295	COG2032	superoxide dismutase activity
BSP_RS07300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSP_RS07330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSP_RS07335	COG0248	Ppx GppA phosphatase
BSP_RS07345	COG3186	Phenylalanine-4-hydroxylase
BSP_RS07350	COG3724	N-succinylarginine dihydrolase activity
BSP_RS07355	COG1012	belongs to the aldehyde dehydrogenase family
BSP_RS07375	COG0729	surface antigen
BSP_RS07385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSP_RS07475	COG1940	carbohydrate kinase activity
BSP_RS07485	COG0343	queuine tRNA-ribosyltransferase activity
BSP_RS07510	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BSP_RS07565	COG0602	queuosine metabolic process
BSP_RS07575	COG0501	Belongs to the peptidase M48B family
BSP_RS07605	COG1690	Belongs to the RtcB family
BSP_RS07620	COG5002	protein histidine kinase activity
BSP_RS07625	COG0745	RESPONSE REGULATOR receiver
BSP_RS07630	COG4771	TonB-dependent receptor
BSP_RS07635	COG0482	sulfurtransferase activity
BSP_RS07645	COG1749	Flagellar hook protein flgE
BSP_RS07675	COG1573	uracil-dna glycosylase
BSP_RS07680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSP_RS07705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSP_RS07715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSP_RS07750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSP_RS07770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSP_RS07770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSP_RS07780	COG0519	Catalyzes the synthesis of GMP from XMP
BSP_RS07780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSP_RS07880	COG4774	siderophore transport
BSP_RS07880	COG1629	transport
BSP_RS07885	COG4191	Histidine kinase
BSP_RS07885	COG0784	Response regulator, receiver
BSP_RS07905	COG0681	Belongs to the peptidase S26 family
BSP_RS07910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSP_RS07915	COG0439	Biotin carboxylase
BSP_RS07920	COG0511	ligase activity, forming carbon-carbon bonds
BSP_RS07945	COG2022	thiamine diphosphate biosynthetic process
BSP_RS07965	COG3739	integral membrane protein
BSP_RS07970	COG2200	EAL domain
BSP_RS07980	COG0494	nUDIX hydrolase
BSP_RS08000	COG1472	Belongs to the glycosyl hydrolase 3 family
BSP_RS08035	COG0488	(ABC) transporter
BSP_RS08040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSP_RS08045	COG0723	plastoquinol--plastocyanin reductase activity
BSP_RS08050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSP_RS08055	COG2857	Cytochrome c1
BSP_RS08055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSP_RS08060	COG2234	aminopeptidase activity
BSP_RS08085	COG0012	GTP binding
BSP_RS08090	COG2847	Copper chaperone PCu(A)C
BSP_RS08110	COG0193	aminoacyl-tRNA hydrolase activity
BSP_RS08120	COG0784	Response regulator, receiver
BSP_RS08120	COG2205	protein histidine kinase activity
BSP_RS08130	COG0573	inorganic phosphate transmembrane transporter activity
BSP_RS08140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSP_RS08150	COG0745	RESPONSE REGULATOR receiver
BSP_RS08155	COG1462	curli production assembly transport component CsgG
BSP_RS08160	COG1462	curli production assembly transport component CsgG
BSP_RS08185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSP_RS08190	COG3240	lipase activity
BSP_RS08200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSP_RS08205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSP_RS08220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSP_RS08230	COG4152	abc transporter atp-binding protein
BSP_RS08240	COG0739	heme binding
BSP_RS08280	COG3321	synthase
BSP_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS08280	COG0604	alcohol dehydrogenase
BSP_RS08305	COG1132	(ABC) transporter
BSP_RS08315	COG0483	inositol monophosphate 1-phosphatase activity
BSP_RS08320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSP_RS08360	COG0352	thiamine-phosphate diphosphorylase activity
BSP_RS08365	COG2205	protein histidine kinase activity
BSP_RS08390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSP_RS08395	COG0484	heat shock protein binding
BSP_RS08410	COG1376	ErfK ybiS ycfS ynhG family protein
BSP_RS08435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSP_RS08440	COG0051	transcription antitermination factor activity, RNA binding
BSP_RS08445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSP_RS08455	COG0089	rRNA binding
BSP_RS08460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSP_RS08465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSP_RS08470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSP_RS08475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSP_RS08480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSP_RS08490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSP_RS08495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSP_RS08510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSP_RS08515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSP_RS08520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSP_RS08525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSP_RS08540	COG0200	Binds to the 23S rRNA
BSP_RS08545	COG0201	protein transport
BSP_RS08550	COG0563	adenylate kinase activity
BSP_RS08575	COG0203	ribosomal protein L17
BSP_RS08595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSP_RS08620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSP_RS08630	COG0235	Class ii aldolase
BSP_RS08640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSP_RS08645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSP_RS08650	COG3474	cytochrome
BSP_RS08660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BSP_RS08660	COG1918	ferrous iron import across plasma membrane
BSP_RS08680	COG2155	Conserved Protein
BSP_RS08695	COG4221	oxidoreductase activity
BSP_RS08745	COG4771	TonB-dependent receptor
BSP_RS08755	COG0714	Associated with various cellular activities
BSP_RS08810	COG4771	TonB-dependent receptor
BSP_RS08820	COG4977	sequence-specific DNA binding
BSP_RS08820	COG1917	Cupin 2, conserved barrel domain protein
BSP_RS08825	COG1012	belongs to the aldehyde dehydrogenase family
BSP_RS08845	COG1024	Enoyl-CoA hydratase
BSP_RS08870	COG0183	Belongs to the thiolase family
BSP_RS08880	COG1024	Enoyl-CoA hydratase
BSP_RS08885	COG1960	acyl-CoA dehydrogenase activity
BSP_RS08910	COG0582	viral genome integration into host DNA
BSP_RS08920	COG0531	amino acid
BSP_RS08945	COG0154	amidase activity
BSP_RS08960	COG1960	acyl-CoA dehydrogenase activity
BSP_RS08965	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BSP_RS08980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSP_RS09005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSP_RS09030	COG0438	transferase activity, transferring glycosyl groups
BSP_RS09045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BSP_RS09060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSP_RS09065	COG0649	NAD binding
BSP_RS09095	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSP_RS09110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSP_RS09135	COG1007	ATP synthesis coupled electron transport
BSP_RS09145	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSP_RS09165	COG0442	prolyl-tRNA aminoacylation
BSP_RS09175	COG1136	(ABC) transporter
BSP_RS09180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSP_RS09200	COG0052	Belongs to the universal ribosomal protein uS2 family
BSP_RS09210	COG0528	UMP kinase activity
BSP_RS09215	COG0233	cytoplasmic translational termination
BSP_RS09220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSP_RS09225	COG0575	Belongs to the CDS family
BSP_RS09235	COG0750	zinc metalloprotease
BSP_RS09240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSP_RS09250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSP_RS09255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSP_RS09260	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSP_RS09265	COG3494	Protein of unknown function (DUF1009)
BSP_RS09270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSP_RS09275	COG0372	Belongs to the citrate synthase family
BSP_RS09280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSP_RS09285	COG0658	competence protein
BSP_RS09285	COG2333	competence protein COMEC
BSP_RS09290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSP_RS09295	COG0134	indole-3-glycerol-phosphate synthase activity
BSP_RS09315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSP_RS09325	COG0149	triose-phosphate isomerase activity
BSP_RS09360	COG0113	porphobilinogen synthase activity
BSP_RS09380	COG0545	Peptidyl-prolyl cis-trans isomerase
BSP_RS09385	COG0668	transmembrane transport
BSP_RS09395	COG5265	(ABC) transporter
BSP_RS09405	COG2201	protein-glutamate methylesterase activity
BSP_RS09415	COG4974	Belongs to the 'phage' integrase family
BSP_RS09425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSP_RS09435	COG2070	2-Nitropropane dioxygenase
BSP_RS09450	COG1187	pseudouridine synthase activity
BSP_RS09455	COG0742	ribosomal rna small subunit methyltransferase
BSP_RS09475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSP_RS09485	COG3549	Plasmid maintenance system killer
BSP_RS09505	COG1764	response to oxidative stress
BSP_RS09525	COG0739	heme binding
BSP_RS09530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSP_RS09545	COG3876	Protein conserved in bacteria
BSP_RS09570	COG1252	NADH dehydrogenase
BSP_RS09580	COG2945	thiolester hydrolase activity
BSP_RS09585	COG1959	2 iron, 2 sulfur cluster binding
BSP_RS09590	COG1104	cysteine desulfurase activity
BSP_RS09595	COG0719	Fe-S assembly protein
BSP_RS09610	COG0396	ATPase activity
BSP_RS09615	COG0719	Fe-S assembly protein
BSP_RS09620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSP_RS09630	COG0316	Belongs to the HesB IscA family
BSP_RS09640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSP_RS09645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BSP_RS09655	COG2084	Dehydrogenase
BSP_RS09665	COG1960	acyl-CoA dehydrogenase activity
BSP_RS09675	COG0009	L-threonylcarbamoyladenylate synthase
BSP_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS09720	COG0531	amino acid
BSP_RS09725	COG1643	Atp-dependent helicase
BSP_RS09735	COG0477	Major facilitator Superfamily
BSP_RS09740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSP_RS09745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSP_RS09745	COG0116	Belongs to the methyltransferase superfamily
BSP_RS09765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSP_RS09770	COG1120	ATPase activity
BSP_RS09775	COG0741	lytic transglycosylase activity
BSP_RS09780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSP_RS09795	COG1573	uracil-dna glycosylase
BSP_RS09805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSP_RS09810	COG1758	RNA polymerase activity
BSP_RS09830	COG0736	holo-[acyl-carrier-protein] synthase activity
BSP_RS09835	COG0681	Belongs to the peptidase S26 family
BSP_RS09870	COG1381	Involved in DNA repair and RecF pathway recombination
BSP_RS09950	COG0513	Belongs to the DEAD box helicase family
BSP_RS09965	COG0587	DNA-directed DNA polymerase activity
BSP_RS09970	COG2814	Major facilitator Superfamily
BSP_RS09975	COG0583	DNA-binding transcription factor activity
BSP_RS09985	COG2264	protein methyltransferase activity
BSP_RS09990	COG0006	proline dipeptidase activity
BSP_RS10005	COG0546	phosphoglycolate phosphatase activity
BSP_RS10025	COG0436	Aminotransferase
BSP_RS10035	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSP_RS10045	COG0077	Prephenate dehydratase
BSP_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS10060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSP_RS10075	COG0328	RNA-DNA hybrid ribonuclease activity
BSP_RS10080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSP_RS10085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSP_RS10090	COG0805	protein transport
BSP_RS10095	COG0174	glutamine synthetase
BSP_RS10100	COG0347	Belongs to the P(II) protein family
BSP_RS10105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSP_RS10105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSP_RS10110	COG0477	Major facilitator Superfamily
BSP_RS10115	COG2205	protein histidine kinase activity
BSP_RS10115	COG0784	Response regulator, receiver
BSP_RS10125	COG0330	HflC and HflK could
BSP_RS10135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSP_RS10145	COG0415	Belongs to the DNA photolyase family
BSP_RS10150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSP_RS10155	COG2897	thiosulfate sulfurtransferase activity
BSP_RS10160	COG1301	dicarboxylic acid transport
BSP_RS10165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSP_RS10170	COG0626	cystathionine gamma-synthase activity
BSP_RS10180	COG0187	DNA topoisomerase II activity
BSP_RS10215	COG0784	Response regulator, receiver
BSP_RS10225	COG1228	amidohydrolase
BSP_RS10235	COG0402	S-adenosylhomocysteine deaminase activity
BSP_RS10245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSP_RS10250	COG2986	histidine ammonia-lyase
BSP_RS10260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSP_RS10270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BSP_RS10315	COG1741	Belongs to the pirin family
BSP_RS10320	COG0583	DNA-binding transcription factor activity
BSP_RS10340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSP_RS10355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSP_RS10365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSP_RS10370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSP_RS10375	COG0436	Aminotransferase
BSP_RS10380	COG0194	GDP metabolic process
BSP_RS10385	COG1561	YicC-like family, N-terminal region
BSP_RS10390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSP_RS10395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSP_RS10410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSP_RS10430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSP_RS10445	COG0525	valine-tRNA ligase activity
BSP_RS10460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSP_RS10480	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSP_RS10495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSP_RS10500	COG1845	cytochrome c oxidase, subunit III
BSP_RS10505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSP_RS10515	COG0477	Major facilitator Superfamily
BSP_RS10525	COG2272	Belongs to the type-B carboxylesterase lipase family
BSP_RS10535	COG2271	Major facilitator Superfamily
BSP_RS10545	COG1609	Transcriptional regulator
BSP_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS10570	COG2721	sulfolactate sulfo-lyase activity
BSP_RS10575	COG0246	Mannitol dehydrogenase
BSP_RS10580	COG1904	glucuronate isomerase
BSP_RS10585	COG0772	Belongs to the SEDS family
BSP_RS10620	COG0475	glutathione-regulated potassium exporter activity
BSP_RS10625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSP_RS10630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSP_RS10635	COG1862	Preprotein translocase
BSP_RS10655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSP_RS10660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSP_RS10675	COG0393	Putative heavy-metal-binding
BSP_RS10680	COG1902	pentaerythritol trinitrate reductase activity
BSP_RS10685	COG0489	protein tyrosine kinase activity
BSP_RS10690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSP_RS10720	COG0114	fumarate hydratase activity
BSP_RS10775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSP_RS10790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSP_RS10795	COG0386	Belongs to the glutathione peroxidase family
BSP_RS10800	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSP_RS10805	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSP_RS10805	COG0022	dehydrogenase e1 component
BSP_RS10810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSP_RS10820	COG0148	phosphopyruvate hydratase activity
BSP_RS10835	COG0110	maltose O-acetyltransferase activity
BSP_RS10845	COG2867	negative regulation of translational initiation
BSP_RS10855	COG0318	PFAM AMP-dependent synthetase and ligase
BSP_RS10855	COG0204	Acyl-transferase
BSP_RS10860	COG3384	dioxygenase
BSP_RS10865	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSP_RS10880	COG3956	TIGRFAM MazG family protein
BSP_RS10890	COG0025	NhaP-type Na H and K H
BSP_RS10895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSP_RS10900	COG1923	regulation of RNA biosynthetic process
BSP_RS10905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSP_RS10910	COG2204	response regulator
BSP_RS10915	COG5000	phosphorelay sensor kinase activity
BSP_RS10920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSP_RS10945	COG1295	ribonuclease BN
BSP_RS10955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSP_RS10965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSP_RS10970	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BSP_RS10975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BSP_RS10975	COG0321	lipoyl(octanoyl) transferase activity
BSP_RS10980	COG0084	hydrolase, TatD family'
BSP_RS10990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSP_RS10995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSP_RS11020	COG0745	RESPONSE REGULATOR receiver
BSP_RS11025	COG2205	protein histidine kinase activity
BSP_RS11030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BSP_RS11040	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BSP_RS11045	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BSP_RS11090	COG0745	RESPONSE REGULATOR receiver
BSP_RS11150	COG1278	Cold shock
BSP_RS11160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSP_RS11160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BSP_RS11170	COG3243	poly(R)-hydroxyalkanoic acid synthase
BSP_RS11180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSP_RS11190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSP_RS11195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSP_RS11220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSP_RS11230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BSP_RS11235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSP_RS11300	COG0798	PFAM Bile acid sodium symporter
BSP_RS11315	COG3424	synthase
BSP_RS11320	COG1755	Isoprenylcysteine carboxyl methyltransferase
BSP_RS11335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSP_RS11340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSP_RS11410	COG2132	Multicopper oxidase
BSP_RS11430	COG1937	Protein conserved in bacteria
BSP_RS11490	COG0672	)-iron permease
BSP_RS11495	COG2890	protein-(glutamine-N5) methyltransferase activity
BSP_RS11500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSP_RS11505	COG2124	cytochrome p450
BSP_RS11550	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BSP_RS11560	COG2948	multi-organism process
BSP_RS11585	COG3451	type IV secretory pathway VirB4
BSP_RS11600	COG4962	Type ii secretion system protein e
BSP_RS11640	COG4206	TonB-dependent receptor
BSP_RS11650	COG1595	DNA-templated transcription, initiation
BSP_RS11715	COG1196	nuclear chromosome segregation
BSP_RS11790	COG2003	Belongs to the UPF0758 family
BSP_RS11795	COG0582	viral genome integration into host DNA
BSP_RS11820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSP_RS11845	COG0741	lytic transglycosylase activity
BSP_RS11855	COG2948	multi-organism process
BSP_RS11880	COG3451	type IV secretory pathway VirB4
BSP_RS11895	COG4962	Type ii secretion system protein e
BSP_RS11950	COG1742	UPF0060 membrane protein
BSP_RS11965	COG0671	phosphoesterase, PA-phosphatase related
BSP_RS11980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSP_RS11995	COG0745	RESPONSE REGULATOR receiver
BSP_RS12015	COG2003	Belongs to the UPF0758 family
BSP_RS12085	COG5002	protein histidine kinase activity
BSP_RS12095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSP_RS12100	COG0784	Response regulator, receiver
BSP_RS12100	COG2198	Histidine kinase
BSP_RS12100	COG2205	protein histidine kinase activity
BSP_RS12105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSP_RS12110	COG1201	RNA secondary structure unwinding
BSP_RS12135	COG0776	regulation of translation
BSP_RS12140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSP_RS12145	COG0416	fatty acid biosynthetic process
BSP_RS12165	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSP_RS12175	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSP_RS12185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSP_RS12200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSP_RS12200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSP_RS12205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSP_RS12210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSP_RS12225	COG0156	8-amino-7-oxononanoate synthase activity
BSP_RS12235	COG1309	transcriptional regulator
BSP_RS12240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSP_RS12250	COG0049	tRNA binding
BSP_RS12255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSP_RS12280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSP_RS12285	COG0085	RNA polymerase activity
BSP_RS12300	COG0222	ribosome binding
BSP_RS12305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSP_RS12320	COG1733	regulation of RNA biosynthetic process
BSP_RS12325	COG2910	NAD(P)H-binding
BSP_RS12335	COG0081	regulation of translation
BSP_RS12340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSP_RS12345	COG0250	Participates in transcription elongation, termination and antitermination
BSP_RS12350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSP_RS12360	COG1253	flavin adenine dinucleotide binding
BSP_RS12375	COG1187	pseudouridine synthase activity
BSP_RS12395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSP_RS12415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSP_RS12425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSP_RS12430	COG1024	Enoyl-CoA hydratase
BSP_RS12440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSP_RS12445	COG0360	Binds together with S18 to 16S ribosomal RNA
BSP_RS12450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSP_RS12455	COG0359	binds to the 23S rRNA
BSP_RS12465	COG0305	Participates in initiation and elongation during chromosome replication
BSP_RS12470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSP_RS12485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSP_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
BSP_RS12505	COG1051	belongs to the nudix hydrolase family
BSP_RS12510	COG1160	GTP binding
BSP_RS12555	COG1393	Belongs to the ArsC family
BSP_RS12565	COG3842	ATPase activity
BSP_RS12570	COG1950	PFAM Membrane protein of
BSP_RS12575	COG0537	adenosine 5'-monophosphoramidase activity
BSP_RS12585	COG3386	PFAM SMP-30 Gluconolaconase
BSP_RS12605	COG4795	General secretion pathway protein
BSP_RS12660	COG2234	aminopeptidase activity
BSP_RS12665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSP_RS12675	COG0667	Aldo Keto reductase
BSP_RS12705	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSP_RS12715	COG0424	maF-like protein
BSP_RS12720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSP_RS12765	COG0321	lipoyl(octanoyl) transferase activity
BSP_RS12780	COG2239	Acts as a magnesium transporter
BSP_RS12790	COG1960	acyl-CoA dehydrogenase activity
BSP_RS12805	COG5442	Flagellar protein FlaF
BSP_RS12825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSP_RS12835	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BSP_RS12890	COG3789	protein conserved in bacteria
BSP_RS12900	COG0754	glutathionylspermidine amidase activity
BSP_RS12935	COG3540	Alkaline phosphatase
BSP_RS12965	COG1215	transferase activity, transferring glycosyl groups
BSP_RS12990	COG0625	glutathione transferase activity
BSP_RS13000	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSP_RS13010	COG0154	amidase activity
BSP_RS13015	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSP_RS13020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSP_RS13030	COG0540	Belongs to the ATCase OTCase family
BSP_RS13035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSP_RS13045	COG0584	glycerophosphoryl diester phosphodiesterase
BSP_RS13055	COG0758	DNA mediated transformation
BSP_RS13060	COG1754	DNA topoisomerase type I activity
BSP_RS13060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSP_RS13070	COG0395	ABC-type sugar transport system, permease component
BSP_RS13075	COG1175	transmembrane transport
BSP_RS13080	COG1653	transport
BSP_RS13095	COG1609	Transcriptional regulator
BSP_RS13100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSP_RS13115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSP_RS13130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSP_RS13135	COG0248	Ppx GppA phosphatase
BSP_RS13140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSP_RS13145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSP_RS13150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSP_RS13155	COG3590	peptidase
BSP_RS13180	COG0488	(ABC) transporter
BSP_RS13195	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSP_RS13210	COG0142	geranyltranstransferase activity
BSP_RS13215	COG2242	protein methyltransferase activity
BSP_RS13215	COG2241	protein methyltransferase activity
BSP_RS13235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSP_RS13245	COG2226	methyltransferase
BSP_RS13265	COG1410	methionine synthase
BSP_RS13265	COG0646	methionine synthase
BSP_RS13290	COG0318	PFAM AMP-dependent synthetase and ligase
BSP_RS13300	COG2070	2-Nitropropane dioxygenase
BSP_RS13310	COG1278	Cold shock
BSP_RS13330	COG0626	cystathionine gamma-synthase activity
BSP_RS13345	COG0557	exoribonuclease II activity
BSP_RS13355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSP_RS13370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSP_RS13375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BSP_RS13420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSP_RS13435	COG1686	Belongs to the peptidase S11 family
BSP_RS13440	COG1793	dna ligase
BSP_RS13445	COG2205	protein histidine kinase activity
BSP_RS13445	COG0784	Response regulator, receiver
BSP_RS13450	COG5007	Belongs to the BolA IbaG family
BSP_RS13470	COG1530	ribonuclease E activity
BSP_RS13490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSP_RS13505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSP_RS13510	COG0861	Integral membrane protein TerC family
BSP_RS13515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSP_RS13520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSP_RS13525	COG0640	Transcriptional regulator
BSP_RS13530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSP_RS13535	COG0534	Mate efflux family protein
BSP_RS13570	COG0542	response to heat
BSP_RS13630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSP_RS13640	COG1611	Belongs to the LOG family
BSP_RS13650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSP_RS13665	COG1706	bacterial-type flagellum-dependent cell motility
BSP_RS13670	COG3951	Flagellar rod assembly protein muramidase FlgJ
BSP_RS13690	COG0408	coproporphyrinogen oxidase activity
BSP_RS13705	COG2855	membrane
BSP_RS13710	COG0519	Catalyzes the synthesis of GMP from XMP
BSP_RS13710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSP_RS13715	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSP_RS13725	COG4771	TonB-dependent receptor
BSP_RS13730	COG0215	cysteine-tRNA ligase activity
BSP_RS13735	COG0302	gtp cyclohydrolase
BSP_RS13740	COG0848	biopolymer transport protein
BSP_RS13745	COG0405	Gamma-glutamyltransferase
BSP_RS13760	COG0656	L-ascorbic acid biosynthetic process
BSP_RS13770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BSP_RS13795	COG0312	modulator of DNA gyrase
BSP_RS13800	COG0483	inositol monophosphate 1-phosphatase activity
BSP_RS13825	COG0697	spore germination
BSP_RS13835	COG1132	(ABC) transporter
BSP_RS13840	COG2121	Domain of unknown function (DUF374)
BSP_RS13845	COG1519	Transferase
BSP_RS13850	COG1663	tetraacyldisaccharide 4'-kinase activity
BSP_RS13855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSP_RS13875	COG0151	Belongs to the GarS family
BSP_RS13885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSP_RS13900	COG0018	arginyl-trna synthetase
BSP_RS13915	COG1335	isochorismatase
BSP_RS13920	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BSP_RS13925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSP_RS13930	COG0509	glycine decarboxylation via glycine cleavage system
BSP_RS13940	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSP_RS13975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSP_RS13980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSP_RS13985	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSP_RS13990	COG0356	it plays a direct role in the translocation of protons across the membrane
BSP_RS14000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSP_RS14005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSP_RS14010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSP_RS14015	COG1472	Belongs to the glycosyl hydrolase 3 family
BSP_RS14030	COG0316	Belongs to the HesB IscA family
BSP_RS14060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSP_RS14080	COG0354	folic acid binding
BSP_RS14090	COG2818	Glycosylase
BSP_RS14110	COG0469	pyruvate kinase activity
BSP_RS14120	COG2354	Protein conserved in bacteria
BSP_RS14125	COG3047	cAMP biosynthetic process
BSP_RS14130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSP_RS14140	COG1294	oxidase, subunit
BSP_RS14150	COG4988	ABC transporter
BSP_RS14155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BSP_RS14160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSP_RS14205	COG4786	Flagellar basal body rod
BSP_RS14210	COG4786	Flagellar basal body rod
BSP_RS14215	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BSP_RS14220	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BSP_RS14250	COG0175	sulfate reduction
BSP_RS14255	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSP_RS14265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSP_RS14265	COG1648	precorrin-2 dehydrogenase activity
BSP_RS14270	COG0583	DNA-binding transcription factor activity
BSP_RS14275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSP_RS14300	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSP_RS14310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSP_RS14325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSP_RS14330	COG1881	PFAM PEBP family protein
BSP_RS14335	COG2814	Major facilitator Superfamily
BSP_RS14345	COG0047	phosphoribosylformylglycinamidine synthase activity
BSP_RS14380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSP_RS14395	COG2124	cytochrome p450
BSP_RS14405	COG3540	Alkaline phosphatase
BSP_RS14410	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BSP_RS14420	COG1692	metallophosphoesterase
BSP_RS14435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSP_RS14465	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BSP_RS14475	COG0438	transferase activity, transferring glycosyl groups
BSP_RS14495	COG1194	a g-specific adenine glycosylase
BSP_RS14555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSP_RS14570	COG0275	rRNA processing
BSP_RS14590	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSP_RS14600	COG0616	signal peptide processing
BSP_RS14605	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BSP_RS14625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSP_RS14630	COG1846	Transcriptional regulator
BSP_RS14635	COG0443	Heat shock 70 kDa protein
BSP_RS14650	COG1956	GAF domain-containing protein
BSP_RS14665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSP_RS14665	COG0574	Belongs to the PEP-utilizing enzyme family
BSP_RS14715	COG2002	toxin-antitoxin pair type II binding
BSP_RS14730	COG1573	uracil-dna glycosylase
BSP_RS14735	COG0741	lytic transglycosylase activity
BSP_RS14750	COG0529	Catalyzes the synthesis of activated sulfate
BSP_RS14750	COG2895	sulfate adenylyltransferase (ATP) activity
BSP_RS14755	COG0175	sulfate reduction
BSP_RS14765	COG0318	PFAM AMP-dependent synthetase and ligase
BSP_RS14770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSP_RS14780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BSP_RS14780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSP_RS14795	COG4771	TonB-dependent receptor
BSP_RS14805	COG2211	Major facilitator Superfamily
BSP_RS14810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSP_RS14815	COG0142	geranyltranstransferase activity
BSP_RS14820	COG1722	exodeoxyribonuclease VII activity
BSP_RS14830	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSP_RS14870	COG3920	Histidine kinase
BSP_RS14875	COG0745	RESPONSE REGULATOR receiver
BSP_RS14880	COG5002	protein histidine kinase activity
BSP_RS14890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSP_RS14900	COG2204	response regulator
BSP_RS14905	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSP_RS14915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSP_RS14920	COG1766	The M ring may be actively involved in energy transduction
BSP_RS14930	COG1573	uracil-dna glycosylase
BSP_RS14950	COG0625	glutathione transferase activity
BSP_RS14955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSP_RS14990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSP_RS14995	COG0745	RESPONSE REGULATOR receiver
BSP_RS15025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSP_RS15035	COG1496	oxidoreductase activity
BSP_RS15040	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BSP_RS15055	COG0849	cell division
BSP_RS15065	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSP_RS15070	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSP_RS15075	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
BSP_RS15080	COG4423	Transcription factor
BSP_RS15085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSP_RS15090	COG1966	Carbon starvation protein
BSP_RS15100	COG0300	oxidoreductase activity
BSP_RS15115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSP_RS15140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSP_RS15160	COG0492	ferredoxin-NADP+ reductase activity
BSP_RS15170	COG5001	Diguanylate cyclase
BSP_RS15180	COG0783	Belongs to the Dps family
BSP_RS15185	COG0784	Response regulator, receiver
BSP_RS15185	COG4191	Histidine kinase
BSP_RS15215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSP_RS15245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSP_RS15270	COG2169	Transcriptional regulator
BSP_RS15280	COG0471	metal ion transport
BSP_RS15280	COG3273	potassium ion transport
BSP_RS15320	COG4771	TonB-dependent receptor
BSP_RS15325	COG0556	nucleotide-excision repair
BSP_RS15345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSP_RS15355	COG0784	Response regulator, receiver
BSP_RS15355	COG5002	protein histidine kinase activity
BSP_RS15360	COG3609	addiction module antidote protein, CC2985 family
BSP_RS15365	COG3668	Plasmid stabilization system
BSP_RS15375	COG1064	alcohol dehydrogenase
BSP_RS15390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSP_RS15400	COG0588	phosphoglycerate mutase activity
BSP_RS15410	COG0167	dihydroorotate dehydrogenase activity
BSP_RS15415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSP_RS15415	COG2205	protein histidine kinase activity
BSP_RS15440	COG2815	serine threonine protein kinase
BSP_RS15440	COG0515	serine threonine protein kinase
BSP_RS15480	COG1278	Cold shock
BSP_RS15485	COG0431	NADPH-dependent FMN reductase
BSP_RS15515	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSP_RS15520	COG0109	protoheme IX farnesyltransferase activity
BSP_RS15525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSP_RS15550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSP_RS15560	COG0596	Alpha beta hydrolase
BSP_RS15565	COG1476	TRANSCRIPTIONal
BSP_RS15580	COG2264	protein methyltransferase activity
BSP_RS15585	COG0693	protein deglycase activity
BSP_RS15595	COG2321	neutral zinc metallopeptidase
BSP_RS15600	COG0033	Phosphoglucomutase
BSP_RS15640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSP_RS15655	COG0626	cystathionine gamma-synthase activity
BSP_RS15675	COG0505	Belongs to the CarA family
BSP_RS15695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSP_RS15710	COG4993	Dehydrogenase
BSP_RS15725	COG0004	ammonium transporteR
BSP_RS15730	COG0071	Belongs to the small heat shock protein (HSP20) family
BSP_RS15740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSP_RS15745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSP_RS15750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSP_RS15755	COG1137	ATPase activity
BSP_RS15780	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BSP_RS15790	COG1677	Flagellar hook-basal body complex protein FliE
BSP_RS15795	COG1558	bacterial-type flagellum-dependent cell motility
BSP_RS15805	COG3190	flagellar
BSP_RS15810	COG1338	Plays a role in the flagellum-specific transport system
BSP_RS15815	COG0776	regulation of translation
BSP_RS15835	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BSP_RS15840	COG4115	mRNA cleavage
BSP_RS15845	COG2161	toxin-antitoxin pair type II binding
BSP_RS15850	COG1960	acyl-CoA dehydrogenase activity
BSP_RS15855	COG1960	acyl-CoA dehydrogenase activity
BSP_RS15860	COG0789	Transcriptional regulator
BSP_RS15870	COG3655	Transcriptional regulator
BSP_RS15880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSP_RS15905	COG1960	acyl-CoA dehydrogenase activity
BSP_RS15910	COG1960	acyl-CoA dehydrogenase activity
BSP_RS15950	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSP_RS15955	COG2205	protein histidine kinase activity
BSP_RS15960	COG0745	RESPONSE REGULATOR receiver
BSP_RS15965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSP_RS15975	COG1138	Cytochrome C-type biogenesis protein
BSP_RS15980	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BSP_RS15995	COG1131	(ABC) transporter
BSP_RS16000	COG0842	Transport permease protein
BSP_RS16015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSP_RS16020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSP_RS16065	COG1396	sequence-specific DNA binding
BSP_RS16085	COG2197	response regulator
BSP_RS16090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSP_RS16100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSP_RS16100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSP_RS16105	COG0588	phosphoglycerate mutase activity
BSP_RS16115	COG0840	transmembrane signaling receptor activity
BSP_RS16125	COG1301	dicarboxylic acid transport
BSP_RS16130	COG4191	Histidine kinase
BSP_RS16135	COG2204	response regulator
BSP_RS16140	COG0784	Response regulator, receiver
BSP_RS16140	COG2205	protein histidine kinase activity
BSP_RS16140	COG2198	Histidine kinase
BSP_RS16145	COG0268	Binds directly to 16S ribosomal RNA