locus-tag	class	description
FKQ52_RS00010	COG4771	TonB-dependent receptor
FKQ52_RS00020	COG0137	argininosuccinate synthase activity
FKQ52_RS00035	COG1280	lysine exporter protein (LysE YggA)
FKQ52_RS00055	COG0138	bifunctional purine biosynthesis protein purh
FKQ52_RS00095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FKQ52_RS00100	COG2835	tetraacyldisaccharide 4'-kinase activity
FKQ52_RS00105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKQ52_RS00110	COG1674	ftsk spoiiie
FKQ52_RS00115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FKQ52_RS00125	COG0583	DNA-binding transcription factor activity
FKQ52_RS00130	COG2814	Major facilitator Superfamily
FKQ52_RS00135	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS00140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FKQ52_RS00145	COG0352	thiamine-phosphate diphosphorylase activity
FKQ52_RS00220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FKQ52_RS00225	COG1981	membrane
FKQ52_RS00240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FKQ52_RS00245	COG0424	maF-like protein
FKQ52_RS00255	COG0237	dephospho-CoA kinase activity
FKQ52_RS00260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FKQ52_RS00265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FKQ52_RS00275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FKQ52_RS00280	COG0433	COG0433 Predicted ATPase
FKQ52_RS00305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FKQ52_RS00315	COG1396	sequence-specific DNA binding
FKQ52_RS00335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKQ52_RS00340	COG1702	phosphate starvation-inducible protein PhoH
FKQ52_RS00350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FKQ52_RS00355	COG1396	sequence-specific DNA binding
FKQ52_RS00365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FKQ52_RS00370	COG0756	dUTP diphosphatase activity
FKQ52_RS00380	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FKQ52_RS00385	COG0484	heat shock protein binding
FKQ52_RS00390	COG0443	Heat shock 70 kDa protein
FKQ52_RS00400	COG0840	transmembrane signaling receptor activity
FKQ52_RS00405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FKQ52_RS00415	COG4771	TonB-dependent receptor
FKQ52_RS00435	COG2086	electron transfer activity
FKQ52_RS00455	COG1872	DUF167
FKQ52_RS00460	COG0402	S-adenosylhomocysteine deaminase activity
FKQ52_RS00470	COG1671	Belongs to the UPF0178 family
FKQ52_RS00490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FKQ52_RS00505	COG2154	pterin-4-alpha-carbinolamine dehydratase
FKQ52_RS00515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKQ52_RS00550	COG0596	Alpha beta hydrolase
FKQ52_RS00555	COG1196	nuclear chromosome segregation
FKQ52_RS00555	COG0741	lytic transglycosylase activity
FKQ52_RS00555	COG0739	heme binding
FKQ52_RS00575	COG3483	tryptophan 2,3-dioxygenase activity
FKQ52_RS00585	COG0335	large ribosomal subunit rRNA binding
FKQ52_RS00590	COG0336	Belongs to the RNA methyltransferase TrmD family
FKQ52_RS00600	COG2081	HI0933 family
FKQ52_RS00605	COG2205	protein histidine kinase activity
FKQ52_RS00605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ52_RS00610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKQ52_RS00610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKQ52_RS00630	COG0101	tRNA pseudouridine synthase activity
FKQ52_RS00650	COG1607	acyl-coa hydrolase
FKQ52_RS00655	COG4566	intracellular signal transduction
FKQ52_RS00660	COG4191	Histidine kinase
FKQ52_RS00670	COG0840	transmembrane signaling receptor activity
FKQ52_RS00685	COG2198	Histidine kinase
FKQ52_RS00685	COG0643	Histidine kinase
FKQ52_RS00690	COG0835	chemotaxis
FKQ52_RS00695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FKQ52_RS00700	COG2201	protein-glutamate methylesterase activity
FKQ52_RS00705	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS00710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FKQ52_RS00730	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS00800	COG2807	transmembrane transport
FKQ52_RS00805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FKQ52_RS00840	COG0459	protein refolding
FKQ52_RS00870	COG0166	Belongs to the GPI family
FKQ52_RS00920	COG2234	aminopeptidase activity
FKQ52_RS00925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FKQ52_RS00930	COG2962	Rard protein
FKQ52_RS00935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKQ52_RS00940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FKQ52_RS00965	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FKQ52_RS00975	COG0612	Peptidase, M16
FKQ52_RS00995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FKQ52_RS01010	COG2205	protein histidine kinase activity
FKQ52_RS01035	COG0633	Ferredoxin
FKQ52_RS01080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKQ52_RS01100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FKQ52_RS01105	COG0339	signal peptide processing
FKQ52_RS01115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FKQ52_RS01130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKQ52_RS01135	COG0228	four-way junction DNA binding
FKQ52_RS01140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FKQ52_RS01145	COG3422	double-strand break repair
FKQ52_RS01150	COG3135	benzoate transporter
FKQ52_RS01155	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FKQ52_RS01165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKQ52_RS01180	COG4946	Tricorn protease homolog
FKQ52_RS01180	COG1506	peptidase
FKQ52_RS01180	COG0823	Involved in the tonB-independent uptake of proteins
FKQ52_RS01185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FKQ52_RS01195	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FKQ52_RS01205	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FKQ52_RS01230	COG0598	Magnesium transport protein CorA
FKQ52_RS01240	COG2755	lipolytic protein G-D-S-L family
FKQ52_RS01240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FKQ52_RS01255	COG3738	Protein conserved in bacteria
FKQ52_RS01260	COG1420	regulation of RNA biosynthetic process
FKQ52_RS01265	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FKQ52_RS01270	COG0412	Dienelactone hydrolase
FKQ52_RS01290	COG1131	(ABC) transporter
FKQ52_RS01315	COG0640	Transcriptional regulator
FKQ52_RS01335	COG0346	lactoylglutathione lyase activity
FKQ52_RS01350	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FKQ52_RS01365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FKQ52_RS01395	COG2885	chlorophyll binding
FKQ52_RS01395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKQ52_RS01420	COG0583	DNA-binding transcription factor activity
FKQ52_RS01425	COG1741	Belongs to the pirin family
FKQ52_RS01430	COG0625	glutathione transferase activity
FKQ52_RS01440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ52_RS01440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FKQ52_RS01445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FKQ52_RS01450	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS01470	COG1131	(ABC) transporter
FKQ52_RS01475	COG0842	Transport permease protein
FKQ52_RS01490	COG0640	Transcriptional regulator
FKQ52_RS01520	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS01525	COG2205	protein histidine kinase activity
FKQ52_RS01530	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FKQ52_RS01535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FKQ52_RS01535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKQ52_RS01560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FKQ52_RS01590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKQ52_RS01600	COG2311	Membrane
FKQ52_RS01605	COG0124	histidyl-tRNA synthetase
FKQ52_RS01620	COG1309	transcriptional regulator
FKQ52_RS01630	COG2267	carboxylic ester hydrolase activity
FKQ52_RS01635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FKQ52_RS01650	COG1999	signal sequence binding
FKQ52_RS01685	COG1309	transcriptional regulator
FKQ52_RS01695	COG2814	Major facilitator Superfamily
FKQ52_RS01700	COG0045	succinate-CoA ligase (ADP-forming) activity
FKQ52_RS01705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FKQ52_RS01710	COG0567	Dehydrogenase, E1 component
FKQ52_RS01715	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKQ52_RS01725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ52_RS01745	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS01755	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS01760	COG2205	protein histidine kinase activity
FKQ52_RS01765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ52_RS01775	COG0670	Belongs to the BI1 family
FKQ52_RS01785	COG0519	Catalyzes the synthesis of GMP from XMP
FKQ52_RS01795	COG1088	dTDP-glucose 4,6-dehydratase activity
FKQ52_RS01815	COG0072	phenylalanine-tRNA ligase activity
FKQ52_RS01815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKQ52_RS01830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FKQ52_RS01835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FKQ52_RS01845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FKQ52_RS01850	COG0859	PFAM glycosyl transferase family 9
FKQ52_RS01855	COG0596	Alpha beta hydrolase
FKQ52_RS01865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FKQ52_RS01870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKQ52_RS01875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKQ52_RS01890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKQ52_RS01895	COG0588	phosphoglycerate mutase activity
FKQ52_RS01900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKQ52_RS01900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKQ52_RS01910	COG0071	Belongs to the small heat shock protein (HSP20) family
FKQ52_RS01950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FKQ52_RS01950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FKQ52_RS01955	COG1217	gtp-binding protein TYPA
FKQ52_RS01960	COG1297	OPT oligopeptide transporter protein
FKQ52_RS02005	COG0268	Binds directly to 16S ribosomal RNA
FKQ52_RS02020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKQ52_RS02065	COG1459	type II secretion system
FKQ52_RS02130	COG3804	dihydrodipicolinate reductase
FKQ52_RS02135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FKQ52_RS02175	COG2814	Major facilitator Superfamily
FKQ52_RS02180	COG4771	TonB-dependent receptor
FKQ52_RS02185	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS02190	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FKQ52_RS02195	COG0183	Belongs to the thiolase family
FKQ52_RS02205	COG2070	2-Nitropropane dioxygenase
FKQ52_RS02210	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS02220	COG0183	Belongs to the thiolase family
FKQ52_RS02230	COG0183	Belongs to the thiolase family
FKQ52_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS02245	COG4771	TonB-dependent receptor
FKQ52_RS02255	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS02280	COG0405	Gamma-glutamyltransferase
FKQ52_RS02290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKQ52_RS02290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FKQ52_RS02295	COG0671	phosphoesterase, PA-phosphatase related
FKQ52_RS02330	COG0673	inositol 2-dehydrogenase activity
FKQ52_RS02340	COG2272	Belongs to the type-B carboxylesterase lipase family
FKQ52_RS02350	COG0642	Histidine kinase
FKQ52_RS02360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FKQ52_RS02370	COG0706	membrane insertase activity
FKQ52_RS02380	COG2267	carboxylic ester hydrolase activity
FKQ52_RS02385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FKQ52_RS02390	COG1073	alpha beta
FKQ52_RS02395	COG1741	Belongs to the pirin family
FKQ52_RS02400	COG1522	sequence-specific DNA binding
FKQ52_RS02425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKQ52_RS02430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FKQ52_RS02435	COG0438	transferase activity, transferring glycosyl groups
FKQ52_RS02445	COG0506	proline dehydrogenase activity
FKQ52_RS02445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FKQ52_RS02445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FKQ52_RS02450	COG0024	Methionine aminopeptidase
FKQ52_RS02470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKQ52_RS02480	COG0463	Glycosyl transferase, family 2
FKQ52_RS02500	COG1272	protein, Hemolysin III
FKQ52_RS02570	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FKQ52_RS02585	COG1957	nucleoside hydrolase
FKQ52_RS02590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKQ52_RS02640	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS02650	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS02665	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FKQ52_RS02690	COG0363	glucosamine-6-phosphate deaminase activity
FKQ52_RS02695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FKQ52_RS02715	COG4774	siderophore transport
FKQ52_RS02720	COG3128	pkhd-type hydroxylase
FKQ52_RS02730	COG1477	protein flavinylation
FKQ52_RS02755	COG2205	protein histidine kinase activity
FKQ52_RS02755	COG0784	Response regulator, receiver
FKQ52_RS02760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKQ52_RS02765	COG1619	proteins homologs of microcin C7 resistance protein MccF
FKQ52_RS02775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FKQ52_RS02785	COG2321	neutral zinc metallopeptidase
FKQ52_RS02815	COG1476	TRANSCRIPTIONal
FKQ52_RS02840	COG0004	ammonium transporteR
FKQ52_RS02850	COG2259	Doxx family
FKQ52_RS02860	COG0366	Alpha amylase catalytic
FKQ52_RS02895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ52_RS02905	COG4464	protein tyrosine phosphatase activity
FKQ52_RS02910	COG2942	2-epimerase
FKQ52_RS02920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FKQ52_RS02925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FKQ52_RS02935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FKQ52_RS02940	COG2089	acid synthase
FKQ52_RS02960	COG1696	Membrane protein involved in D-alanine export
FKQ52_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS03010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FKQ52_RS03025	COG0107	imidazoleglycerol-phosphate synthase activity
FKQ52_RS03030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FKQ52_RS03040	COG1083	cytidylyl-transferase
FKQ52_RS03065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKQ52_RS03095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKQ52_RS03110	COG1609	Transcriptional regulator
FKQ52_RS03115	COG3507	Belongs to the glycosyl hydrolase 43 family
FKQ52_RS03125	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS03140	COG0460	homoserine dehydrogenase
FKQ52_RS03145	COG0626	cystathionine gamma-synthase activity
FKQ52_RS03155	COG0004	ammonium transporteR
FKQ52_RS03215	COG1573	uracil-dna glycosylase
FKQ52_RS03265	COG0538	isocitrate dehydrogenase activity
FKQ52_RS03280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKQ52_RS03300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FKQ52_RS03305	COG2201	protein-glutamate methylesterase activity
FKQ52_RS03315	COG1218	3'(2'),5'-bisphosphate nucleotidase
FKQ52_RS03340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FKQ52_RS03375	COG2205	protein histidine kinase activity
FKQ52_RS03380	COG2166	iron-sulfur cluster assembly
FKQ52_RS03420	COG0513	Belongs to the DEAD box helicase family
FKQ52_RS03450	COG1131	(ABC) transporter
FKQ52_RS03460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FKQ52_RS03490	COG0471	metal ion transport
FKQ52_RS03490	COG3273	potassium ion transport
FKQ52_RS03510	COG0475	glutathione-regulated potassium exporter activity
FKQ52_RS03525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FKQ52_RS03560	COG0783	Belongs to the Dps family
FKQ52_RS03570	COG5001	Diguanylate cyclase
FKQ52_RS03580	COG0492	ferredoxin-NADP+ reductase activity
FKQ52_RS03595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKQ52_RS03610	COG1823	symporter activity
FKQ52_RS03625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FKQ52_RS03635	COG4771	TonB-dependent receptor
FKQ52_RS03650	COG0531	amino acid
FKQ52_RS03655	COG0505	Belongs to the CarA family
FKQ52_RS03675	COG0358	DNA primase activity
FKQ52_RS03680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKQ52_RS03710	COG5507	3-demethylubiquinone-9 3-methyltransferase
FKQ52_RS03730	COG3584	3D domain protein
FKQ52_RS03730	COG1388	LysM domain
FKQ52_RS03735	COG0625	glutathione transferase activity
FKQ52_RS03755	COG1971	Probably functions as a manganese efflux pump
FKQ52_RS03770	COG0583	DNA-binding transcription factor activity
FKQ52_RS03775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FKQ52_RS03790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FKQ52_RS03810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FKQ52_RS03820	COG3300	MHYT domain
FKQ52_RS03820	COG5001	Diguanylate cyclase
FKQ52_RS03825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FKQ52_RS03845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FKQ52_RS03855	COG0271	Belongs to the BolA IbaG family
FKQ52_RS03865	COG1446	asparaginase
FKQ52_RS03870	COG2003	Belongs to the UPF0758 family
FKQ52_RS03875	COG0024	Methionine aminopeptidase
FKQ52_RS03880	COG1489	DNA binding
FKQ52_RS03885	COG1058	Belongs to the CinA family
FKQ52_RS03885	COG1546	Belongs to the CinA family
FKQ52_RS03905	COG5006	permease, DMT superfamily
FKQ52_RS03930	COG4957	zinc ion binding
FKQ52_RS03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKQ52_RS03950	COG1116	anion transmembrane transporter activity
FKQ52_RS03965	COG0488	(ABC) transporter
FKQ52_RS03975	COG2076	Multidrug Resistance protein
FKQ52_RS03980	COG2983	Belongs to the UPF0260 family
FKQ52_RS03985	COG4695	Portal protein
FKQ52_RS04015	COG0484	heat shock protein binding
FKQ52_RS04025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FKQ52_RS04030	COG0643	Histidine kinase
FKQ52_RS04030	COG2198	Histidine kinase
FKQ52_RS04030	COG0784	Response regulator, receiver
FKQ52_RS04045	COG0564	pseudouridine synthase activity
FKQ52_RS04075	COG2205	protein histidine kinase activity
FKQ52_RS04090	COG0793	Belongs to the peptidase S41A family
FKQ52_RS04095	COG0793	Belongs to the peptidase S41A family
FKQ52_RS04110	COG0346	lactoylglutathione lyase activity
FKQ52_RS04115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FKQ52_RS04140	COG1090	epimerase
FKQ52_RS04145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FKQ52_RS04150	COG1692	metallophosphoesterase
FKQ52_RS04160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKQ52_RS04180	COG0047	phosphoribosylformylglycinamidine synthase activity
FKQ52_RS04185	COG2814	Major facilitator Superfamily
FKQ52_RS04190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FKQ52_RS04195	COG1881	PFAM PEBP family protein
FKQ52_RS04205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FKQ52_RS04215	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FKQ52_RS04230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FKQ52_RS04235	COG0739	heme binding
FKQ52_RS04235	COG0741	lytic transglycosylase activity
FKQ52_RS04235	COG1196	nuclear chromosome segregation
FKQ52_RS04240	COG1573	uracil-dna glycosylase
FKQ52_RS04285	COG0751	glycine-tRNA ligase activity
FKQ52_RS04290	COG0584	glycerophosphoryl diester phosphodiesterase
FKQ52_RS04315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ52_RS04320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FKQ52_RS04335	COG0494	nUDIX hydrolase
FKQ52_RS04375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKQ52_RS04390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKQ52_RS04405	COG0629	single-stranded DNA binding
FKQ52_RS04430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FKQ52_RS04435	COG4651	solute:proton antiporter activity
FKQ52_RS04435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKQ52_RS04440	COG1702	phosphate starvation-inducible protein PhoH
FKQ52_RS04465	COG0612	Peptidase, M16
FKQ52_RS04475	COG1462	curli production assembly transport component CsgG
FKQ52_RS04570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FKQ52_RS04575	COG0196	riboflavin kinase activity
FKQ52_RS04580	COG2030	dehydratase
FKQ52_RS04590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FKQ52_RS04605	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS04625	COG4771	TonB-dependent receptor
FKQ52_RS04635	COG0151	Belongs to the GarS family
FKQ52_RS04645	COG3668	Plasmid stabilization system
FKQ52_RS04650	COG0840	transmembrane signaling receptor activity
FKQ52_RS04660	COG1663	tetraacyldisaccharide 4'-kinase activity
FKQ52_RS04665	COG1519	Transferase
FKQ52_RS04670	COG2121	Domain of unknown function (DUF374)
FKQ52_RS04675	COG1132	(ABC) transporter
FKQ52_RS04700	COG0483	inositol monophosphate 1-phosphatase activity
FKQ52_RS04705	COG0312	modulator of DNA gyrase
FKQ52_RS04710	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FKQ52_RS04730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FKQ52_RS04735	COG0656	L-ascorbic acid biosynthetic process
FKQ52_RS04760	COG1609	Transcriptional regulator
FKQ52_RS04775	COG0477	Major facilitator Superfamily
FKQ52_RS04780	COG1012	belongs to the aldehyde dehydrogenase family
FKQ52_RS04790	COG2017	converts alpha-aldose to the beta-anomer
FKQ52_RS04795	COG0129	dihydroxy-acid dehydratase activity
FKQ52_RS04830	COG1874	Beta-galactosidase
FKQ52_RS04835	COG1501	Belongs to the glycosyl hydrolase 31 family
FKQ52_RS04855	COG3734	2-keto-3-deoxy-galactonokinase
FKQ52_RS04860	COG0800	Aldolase
FKQ52_RS04870	COG0469	pyruvate kinase activity
FKQ52_RS04885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FKQ52_RS04900	COG2818	Glycosylase
FKQ52_RS04915	COG1690	Belongs to the RtcB family
FKQ52_RS04925	COG0482	sulfurtransferase activity
FKQ52_RS04935	COG1749	Flagellar hook protein flgE
FKQ52_RS04950	COG1256	bacterial-type flagellum assembly
FKQ52_RS04965	COG1573	uracil-dna glycosylase
FKQ52_RS04970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKQ52_RS04975	COG1127	ABC transporter
FKQ52_RS05015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKQ52_RS05050	COG1506	peptidase
FKQ52_RS05065	COG4771	TonB-dependent receptor
FKQ52_RS05075	COG2308	Evidence 4 Homologs of previously reported genes of
FKQ52_RS05110	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FKQ52_RS05115	COG3537	Alpha-1,2-mannosidase
FKQ52_RS05140	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS05150	COG4771	TonB-dependent receptor
FKQ52_RS05170	COG0531	amino acid
FKQ52_RS05195	COG0154	amidase activity
FKQ52_RS05215	COG0175	sulfate reduction
FKQ52_RS05220	COG1940	carbohydrate kinase activity
FKQ52_RS05225	COG2204	response regulator
FKQ52_RS05230	COG4191	Histidine kinase
FKQ52_RS05235	COG1301	dicarboxylic acid transport
FKQ52_RS05255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FKQ52_RS05270	COG0473	3-isopropylmalate dehydrogenase activity
FKQ52_RS05275	COG0066	3-isopropylmalate dehydratase activity
FKQ52_RS05280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKQ52_RS05290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKQ52_RS05305	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FKQ52_RS05310	COG0129	dihydroxy-acid dehydratase activity
FKQ52_RS05320	COG1858	cytochrome C peroxidase
FKQ52_RS05340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKQ52_RS05355	COG2205	protein histidine kinase activity
FKQ52_RS05355	COG0784	Response regulator, receiver
FKQ52_RS05355	COG2198	Histidine kinase
FKQ52_RS05360	COG0477	Major facilitator Superfamily
FKQ52_RS05375	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FKQ52_RS05385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKQ52_RS05400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FKQ52_RS05420	COG2204	response regulator
FKQ52_RS05430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FKQ52_RS05435	COG0222	ribosome binding
FKQ52_RS05455	COG0545	Peptidyl-prolyl cis-trans isomerase
FKQ52_RS05460	COG0085	RNA polymerase activity
FKQ52_RS05465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKQ52_RS05485	COG0049	tRNA binding
FKQ52_RS05495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKQ52_RS05500	COG1376	ErfK ybiS ycfS ynhG family protein
FKQ52_RS05535	COG0051	transcription antitermination factor activity, RNA binding
FKQ52_RS05540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FKQ52_RS05550	COG0089	rRNA binding
FKQ52_RS05555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FKQ52_RS05565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FKQ52_RS05570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FKQ52_RS05575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FKQ52_RS05580	COG0255	Belongs to the universal ribosomal protein uL29 family
FKQ52_RS05585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FKQ52_RS05590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FKQ52_RS05605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FKQ52_RS05610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FKQ52_RS05615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FKQ52_RS05620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FKQ52_RS05630	COG1841	ribosomal large subunit assembly
FKQ52_RS05635	COG0200	Binds to the 23S rRNA
FKQ52_RS05640	COG0201	protein transport
FKQ52_RS05645	COG0563	adenylate kinase activity
FKQ52_RS05660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FKQ52_RS05670	COG0203	ribosomal protein L17
FKQ52_RS05685	COG1131	(ABC) transporter
FKQ52_RS05700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ52_RS05710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FKQ52_RS05725	COG0564	pseudouridine synthase activity
FKQ52_RS05745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKQ52_RS05755	COG0546	phosphoglycolate phosphatase activity
FKQ52_RS05800	COG0625	glutathione transferase activity
FKQ52_RS05805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FKQ52_RS05810	COG1187	pseudouridine synthase activity
FKQ52_RS05820	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FKQ52_RS05825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKQ52_RS05850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FKQ52_RS05860	COG0235	Class ii aldolase
FKQ52_RS05870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKQ52_RS05875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKQ52_RS05880	COG2852	Protein conserved in bacteria
FKQ52_RS05890	COG3474	cytochrome
FKQ52_RS05900	COG1918	ferrous iron import across plasma membrane
FKQ52_RS05900	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FKQ52_RS05920	COG0537	adenosine 5'-monophosphoramidase activity
FKQ52_RS05925	COG1950	PFAM Membrane protein of
FKQ52_RS05940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FKQ52_RS05975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FKQ52_RS06000	COG0557	exoribonuclease II activity
FKQ52_RS06030	COG0626	cystathionine gamma-synthase activity
FKQ52_RS06045	COG1278	Cold shock
FKQ52_RS06050	COG1278	Cold shock
FKQ52_RS06080	COG3739	integral membrane protein
FKQ52_RS06090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKQ52_RS06095	COG0640	Transcriptional regulator
FKQ52_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS06110	COG2207	Transcriptional regulator
FKQ52_RS06130	COG0784	Response regulator, receiver
FKQ52_RS06140	COG2272	Belongs to the type-B carboxylesterase lipase family
FKQ52_RS06145	COG1609	Transcriptional regulator
FKQ52_RS06165	COG1175	transmembrane transport
FKQ52_RS06170	COG0395	ABC-type sugar transport system, permease component
FKQ52_RS06185	COG0305	Participates in initiation and elongation during chromosome replication
FKQ52_RS06210	COG0359	binds to the 23S rRNA
FKQ52_RS06215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FKQ52_RS06220	COG0360	Binds together with S18 to 16S ribosomal RNA
FKQ52_RS06225	COG1686	Belongs to the peptidase S11 family
FKQ52_RS06240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FKQ52_RS06290	COG1764	response to oxidative stress
FKQ52_RS06295	COG1846	Transcriptional regulator
FKQ52_RS06305	COG5007	Belongs to the BolA IbaG family
FKQ52_RS06320	COG0668	transmembrane transport
FKQ52_RS06330	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FKQ52_RS06350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ52_RS06380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FKQ52_RS06395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FKQ52_RS06400	COG0484	heat shock protein binding
FKQ52_RS06405	COG0259	pyridoxamine-phosphate oxidase activity
FKQ52_RS06415	COG0572	uridine kinase
FKQ52_RS06420	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS06435	COG0501	Belongs to the peptidase M48B family
FKQ52_RS06475	COG2226	methyltransferase
FKQ52_RS06490	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FKQ52_RS06510	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS06515	COG1309	transcriptional regulator
FKQ52_RS06535	COG0142	geranyltranstransferase activity
FKQ52_RS06540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKQ52_RS06545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKQ52_RS06550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FKQ52_RS06555	COG1561	YicC-like family, N-terminal region
FKQ52_RS06560	COG0194	GDP metabolic process
FKQ52_RS06570	COG1024	Enoyl-CoA hydratase
FKQ52_RS06580	COG0798	PFAM Bile acid sodium symporter
FKQ52_RS06595	COG0431	NADPH-dependent FMN reductase
FKQ52_RS06605	COG0436	Aminotransferase
FKQ52_RS06610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FKQ52_RS06615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FKQ52_RS06625	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FKQ52_RS06640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKQ52_RS06680	COG1530	ribonuclease E activity
FKQ52_RS06710	COG0739	heme binding
FKQ52_RS06715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FKQ52_RS06720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FKQ52_RS06730	COG3876	Protein conserved in bacteria
FKQ52_RS06750	COG2945	thiolester hydrolase activity
FKQ52_RS06755	COG1959	2 iron, 2 sulfur cluster binding
FKQ52_RS06765	COG0719	Fe-S assembly protein
FKQ52_RS06775	COG0396	ATPase activity
FKQ52_RS06780	COG0719	Fe-S assembly protein
FKQ52_RS06785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FKQ52_RS06790	COG2151	metal-sulfur cluster biosynthetic enzyme
FKQ52_RS06795	COG0316	Belongs to the HesB IscA family
FKQ52_RS06800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FKQ52_RS06805	COG2011	ABC-type metal ion transport system permease component
FKQ52_RS06810	COG1464	Belongs to the NlpA lipoprotein family
FKQ52_RS06825	COG0513	Belongs to the DEAD box helicase family
FKQ52_RS06850	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FKQ52_RS06865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKQ52_RS06870	COG0649	NAD binding
FKQ52_RS06895	COG2314	TM2 domain
FKQ52_RS06905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FKQ52_RS06920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKQ52_RS06945	COG1007	ATP synthesis coupled electron transport
FKQ52_RS06955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FKQ52_RS06965	COG0528	UMP kinase activity
FKQ52_RS06970	COG0233	cytoplasmic translational termination
FKQ52_RS06975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FKQ52_RS06990	COG0750	zinc metalloprotease
FKQ52_RS06995	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKQ52_RS07005	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKQ52_RS07010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKQ52_RS07020	COG3494	Protein of unknown function (DUF1009)
FKQ52_RS07025	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKQ52_RS07040	COG0681	Belongs to the peptidase S26 family
FKQ52_RS07045	COG0372	Belongs to the citrate synthase family
FKQ52_RS07050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKQ52_RS07055	COG0658	competence protein
FKQ52_RS07055	COG2333	competence protein COMEC
FKQ52_RS07060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FKQ52_RS07070	COG0134	indole-3-glycerol-phosphate synthase activity
FKQ52_RS07080	COG0512	Glutamine amidotransferase of anthranilate synthase
FKQ52_RS07090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FKQ52_RS07100	COG0149	triose-phosphate isomerase activity
FKQ52_RS07165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FKQ52_RS07175	COG2165	general secretion pathway protein
FKQ52_RS07180	COG4970	Tfp pilus assembly protein FimT
FKQ52_RS07190	COG4795	General secretion pathway protein
FKQ52_RS07220	COG1595	DNA-templated transcription, initiation
FKQ52_RS07255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKQ52_RS07285	COG2271	Major facilitator Superfamily
FKQ52_RS07305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FKQ52_RS07310	COG3179	chitinase
FKQ52_RS07320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FKQ52_RS07325	COG3755	Protein conserved in bacteria
FKQ52_RS07335	COG1295	ribonuclease BN
FKQ52_RS07345	COG1546	Belongs to the CinA family
FKQ52_RS07345	COG1058	Belongs to the CinA family
FKQ52_RS07360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKQ52_RS07365	COG5000	phosphorelay sensor kinase activity
FKQ52_RS07370	COG2204	response regulator
FKQ52_RS07375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKQ52_RS07380	COG1923	regulation of RNA biosynthetic process
FKQ52_RS07385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FKQ52_RS07390	COG0025	NhaP-type Na H and K H
FKQ52_RS07400	COG3956	TIGRFAM MazG family protein
FKQ52_RS07405	COG2211	Major facilitator Superfamily
FKQ52_RS07420	COG0655	NAD(P)H dehydrogenase (quinone) activity
FKQ52_RS07425	COG3384	dioxygenase
FKQ52_RS07445	COG2867	negative regulation of translational initiation
FKQ52_RS07450	COG0579	oxidoreductase
FKQ52_RS07475	COG0148	phosphopyruvate hydratase activity
FKQ52_RS07485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FKQ52_RS07490	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKQ52_RS07490	COG0022	dehydrogenase e1 component
FKQ52_RS07500	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKQ52_RS07505	COG0386	Belongs to the glutathione peroxidase family
FKQ52_RS07510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKQ52_RS07520	COG2084	Dehydrogenase
FKQ52_RS07535	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FKQ52_RS07540	COG0501	Belongs to the peptidase M48B family
FKQ52_RS07545	COG1704	LemA family
FKQ52_RS07550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FKQ52_RS07560	COG2070	2-Nitropropane dioxygenase
FKQ52_RS07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKQ52_RS07565	COG0785	Cytochrome C biogenesis protein
FKQ52_RS07570	COG1381	Involved in DNA repair and RecF pathway recombination
FKQ52_RS07610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FKQ52_RS07625	COG0681	Belongs to the peptidase S26 family
FKQ52_RS07630	COG0736	holo-[acyl-carrier-protein] synthase activity
FKQ52_RS07635	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FKQ52_RS07645	COG1611	Belongs to the LOG family
FKQ52_RS07660	COG1758	RNA polymerase activity
FKQ52_RS07665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKQ52_RS07685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKQ52_RS07690	COG1388	LysM domain
FKQ52_RS07690	COG0741	lytic transglycosylase activity
FKQ52_RS07695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FKQ52_RS07700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKQ52_RS07720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKQ52_RS07720	COG0116	Belongs to the methyltransferase superfamily
FKQ52_RS07725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKQ52_RS07750	COG1136	(ABC) transporter
FKQ52_RS07760	COG0442	prolyl-tRNA aminoacylation
FKQ52_RS07800	COG1643	Atp-dependent helicase
FKQ52_RS07805	COG0531	amino acid
FKQ52_RS07830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKQ52_RS07845	COG0525	valine-tRNA ligase activity
FKQ52_RS07860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FKQ52_RS07870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKQ52_RS07885	COG1611	Belongs to the LOG family
FKQ52_RS07900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKQ52_RS07915	COG1706	bacterial-type flagellum-dependent cell motility
FKQ52_RS07930	COG2200	EAL domain
FKQ52_RS07970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FKQ52_RS07995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKQ52_RS08005	COG1862	Preprotein translocase
FKQ52_RS08010	COG4942	peptidase
FKQ52_RS08035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKQ52_RS08045	COG2022	thiamine diphosphate biosynthetic process
FKQ52_RS08050	COG4993	Dehydrogenase
FKQ52_RS08075	COG0439	Biotin carboxylase
FKQ52_RS08080	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FKQ52_RS08095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKQ52_RS08110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FKQ52_RS08135	COG2272	Belongs to the type-B carboxylesterase lipase family
FKQ52_RS08140	COG4771	TonB-dependent receptor
FKQ52_RS08150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FKQ52_RS08170	COG1012	belongs to the aldehyde dehydrogenase family
FKQ52_RS08180	COG0154	amidase activity
FKQ52_RS08185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FKQ52_RS08195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FKQ52_RS08205	COG0540	Belongs to the ATCase OTCase family
FKQ52_RS08210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKQ52_RS08220	COG0758	DNA mediated transformation
FKQ52_RS08225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FKQ52_RS08225	COG1754	DNA topoisomerase type I activity
FKQ52_RS08235	COG2151	metal-sulfur cluster biosynthetic enzyme
FKQ52_RS08235	COG0489	protein tyrosine kinase activity
FKQ52_RS08245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FKQ52_RS08255	COG0077	Prephenate dehydratase
FKQ52_RS08260	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FKQ52_RS08265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKQ52_RS08285	COG0546	phosphoglycolate phosphatase activity
FKQ52_RS08295	COG1733	regulation of RNA biosynthetic process
FKQ52_RS08300	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FKQ52_RS08305	COG1301	dicarboxylic acid transport
FKQ52_RS08320	COG4251	negative regulation of phosphorylation
FKQ52_RS08335	COG3842	ATPase activity
FKQ52_RS08340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKQ52_RS08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKQ52_RS08365	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FKQ52_RS08380	COG4221	oxidoreductase activity
FKQ52_RS08395	COG1160	GTP binding
FKQ52_RS08410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FKQ52_RS08460	COG1393	Belongs to the ArsC family
FKQ52_RS08470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FKQ52_RS08475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKQ52_RS08520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKQ52_RS08530	COG0473	3-isopropylmalate dehydrogenase activity
FKQ52_RS08540	COG0235	Class ii aldolase
FKQ52_RS08550	COG3180	Ammonia monooxygenase
FKQ52_RS08555	COG2851	Citrate transporter
FKQ52_RS08560	COG4771	TonB-dependent receptor
FKQ52_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS08605	COG2207	Transcriptional regulator
FKQ52_RS08610	COG0583	DNA-binding transcription factor activity
FKQ52_RS08615	COG0300	oxidoreductase activity
FKQ52_RS08625	COG0667	Aldo Keto reductase
FKQ52_RS08630	COG0583	DNA-binding transcription factor activity
FKQ52_RS08655	COG2814	Major facilitator Superfamily
FKQ52_RS08660	COG0667	Aldo Keto reductase
FKQ52_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS08670	COG2207	Transcriptional regulator
FKQ52_RS08675	COG0500	methyltransferase
FKQ52_RS08685	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FKQ52_RS08690	COG2207	Transcriptional regulator
FKQ52_RS08735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FKQ52_RS08740	COG4149	molybdate abc transporter
FKQ52_RS08745	COG0725	ABC transporter, periplasmic molybdate-binding protein
FKQ52_RS08750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FKQ52_RS08760	COG0314	molybdopterin synthase activity
FKQ52_RS08765	COG0521	Mo-molybdopterin cofactor biosynthetic process
FKQ52_RS08775	COG0303	'Molybdopterin
FKQ52_RS08785	COG1309	transcriptional regulator
FKQ52_RS08795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FKQ52_RS08805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FKQ52_RS08810	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FKQ52_RS08815	COG2080	2 iron, 2 sulfur cluster binding
FKQ52_RS08820	COG2207	Transcriptional regulator
FKQ52_RS08850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FKQ52_RS08855	COG1733	regulation of RNA biosynthetic process
FKQ52_RS08880	COG0667	Aldo Keto reductase
FKQ52_RS08900	COG0776	regulation of translation
FKQ52_RS08905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKQ52_RS08910	COG0416	fatty acid biosynthetic process
FKQ52_RS08930	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FKQ52_RS08940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FKQ52_RS08950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FKQ52_RS08965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKQ52_RS08965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKQ52_RS08970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FKQ52_RS08975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FKQ52_RS08985	COG2264	protein methyltransferase activity
FKQ52_RS08990	COG0156	8-amino-7-oxononanoate synthase activity
FKQ52_RS09010	COG1024	Enoyl-CoA hydratase
FKQ52_RS09020	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS09025	COG0113	porphobilinogen synthase activity
FKQ52_RS09030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FKQ52_RS09030	COG0321	lipoyl(octanoyl) transferase activity
FKQ52_RS09035	COG0084	hydrolase, TatD family'
FKQ52_RS09045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FKQ52_RS09050	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FKQ52_RS09070	COG0583	DNA-binding transcription factor activity
FKQ52_RS09085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FKQ52_RS09085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FKQ52_RS09095	COG0415	Belongs to the DNA photolyase family
FKQ52_RS09100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKQ52_RS09105	COG2897	thiosulfate sulfurtransferase activity
FKQ52_RS09110	COG1301	dicarboxylic acid transport
FKQ52_RS09115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKQ52_RS09120	COG0626	cystathionine gamma-synthase activity
FKQ52_RS09160	COG1278	Cold shock
FKQ52_RS09175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FKQ52_RS09175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FKQ52_RS09180	COG1494	fructose-1,6-bisphosphatase
FKQ52_RS09190	COG3243	poly(R)-hydroxyalkanoic acid synthase
FKQ52_RS09210	COG2755	lipolytic protein G-D-S-L family
FKQ52_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS09235	COG1472	Belongs to the glycosyl hydrolase 3 family
FKQ52_RS09240	COG4771	TonB-dependent receptor
FKQ52_RS09245	COG1609	Transcriptional regulator
FKQ52_RS09255	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FKQ52_RS09260	COG0519	Catalyzes the synthesis of GMP from XMP
FKQ52_RS09260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKQ52_RS09270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKQ52_RS09270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKQ52_RS09295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FKQ52_RS09310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FKQ52_RS09315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FKQ52_RS09325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FKQ52_RS09340	COG0488	(ABC) transporter
FKQ52_RS09360	COG3046	protein related to deoxyribodipyrimidine photolyase
FKQ52_RS09390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FKQ52_RS09410	COG0742	ribosomal rna small subunit methyltransferase
FKQ52_RS09415	COG1187	pseudouridine synthase activity
FKQ52_RS09420	COG0590	tRNA wobble adenosine to inosine editing
FKQ52_RS09430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FKQ52_RS09440	COG4974	Belongs to the 'phage' integrase family
FKQ52_RS09450	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS09465	COG5265	(ABC) transporter
FKQ52_RS09510	COG1215	transferase activity, transferring glycosyl groups
FKQ52_RS09550	COG0625	glutathione transferase activity
FKQ52_RS09570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FKQ52_RS09575	COG0248	Ppx GppA phosphatase
FKQ52_RS09600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKQ52_RS09610	COG0667	Aldo Keto reductase
FKQ52_RS09635	COG2264	protein methyltransferase activity
FKQ52_RS09655	COG1045	serine acetyltransferase
FKQ52_RS09665	COG0778	Nitroreductase
FKQ52_RS09670	COG1228	amidohydrolase
FKQ52_RS09675	COG2188	Transcriptional regulator
FKQ52_RS09690	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FKQ52_RS09695	COG2986	histidine ammonia-lyase
FKQ52_RS09700	COG1304	FMN binding
FKQ52_RS09710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FKQ52_RS09745	COG2814	Major facilitator Superfamily
FKQ52_RS09750	COG2363	Small membrane protein
FKQ52_RS09770	COG0772	Belongs to the SEDS family
FKQ52_RS09775	COG0768	penicillin binding
FKQ52_RS09800	COG1793	dna ligase
FKQ52_RS09810	COG3537	Alpha-1,2-mannosidase
FKQ52_RS09815	COG0436	Aminotransferase
FKQ52_RS09845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FKQ52_RS09865	COG3279	Response regulator of the LytR AlgR family
FKQ52_RS09875	COG0494	nUDIX hydrolase
FKQ52_RS09880	COG0330	HflC and HflK could
FKQ52_RS09895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FKQ52_RS09900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FKQ52_RS09905	COG0805	protein transport
FKQ52_RS09910	COG0174	glutamine synthetase
FKQ52_RS09915	COG0347	Belongs to the P(II) protein family
FKQ52_RS09920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FKQ52_RS09920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FKQ52_RS09930	COG3022	response to hydroperoxide
FKQ52_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS09950	COG0009	L-threonylcarbamoyladenylate synthase
FKQ52_RS09960	COG3038	cytochrome b561
FKQ52_RS09965	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS10000	COG0784	Response regulator, receiver
FKQ52_RS10010	COG0438	transferase activity, transferring glycosyl groups
FKQ52_RS10025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FKQ52_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS10080	COG2863	cytochrome
FKQ52_RS10090	COG2010	Cytochrome c
FKQ52_RS10090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKQ52_RS10095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKQ52_RS10135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FKQ52_RS10150	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FKQ52_RS10170	COG1902	pentaerythritol trinitrate reductase activity
FKQ52_RS10175	COG0489	protein tyrosine kinase activity
FKQ52_RS10220	COG0114	fumarate hydratase activity
FKQ52_RS10320	COG0187	DNA topoisomerase II activity
FKQ52_RS10330	COG0297	glycogen (starch) synthase activity
FKQ52_RS10370	COG0602	queuosine metabolic process
FKQ52_RS10380	COG5002	protein histidine kinase activity
FKQ52_RS10380	COG0784	Response regulator, receiver
FKQ52_RS10430	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FKQ52_RS10455	COG0343	queuine tRNA-ribosyltransferase activity
FKQ52_RS10470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FKQ52_RS10475	COG0784	Response regulator, receiver
FKQ52_RS10475	COG5002	protein histidine kinase activity
FKQ52_RS10485	COG0729	surface antigen
FKQ52_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
FKQ52_RS10520	COG3724	N-succinylarginine dihydrolase activity
FKQ52_RS10530	COG0477	Major facilitator Superfamily
FKQ52_RS10535	COG3186	Phenylalanine-4-hydroxylase
FKQ52_RS10545	COG0248	Ppx GppA phosphatase
FKQ52_RS10550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKQ52_RS10580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FKQ52_RS10585	COG2032	superoxide dismutase activity
FKQ52_RS10595	COG1132	(ABC) transporter
FKQ52_RS10600	COG0254	rRNA binding
FKQ52_RS10625	COG3321	synthase
FKQ52_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS10625	COG0604	alcohol dehydrogenase
FKQ52_RS10675	COG3447	MASE1 domain protein
FKQ52_RS10675	COG5001	Diguanylate cyclase
FKQ52_RS10675	COG5002	protein histidine kinase activity
FKQ52_RS10680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FKQ52_RS10685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FKQ52_RS10695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FKQ52_RS10705	COG4152	abc transporter atp-binding protein
FKQ52_RS10715	COG0573	inorganic phosphate transmembrane transporter activity
FKQ52_RS10735	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS10750	COG0385	Bile acid
FKQ52_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS10790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKQ52_RS10795	COG3240	lipase activity
FKQ52_RS10800	COG0739	heme binding
FKQ52_RS10805	COG0784	Response regulator, receiver
FKQ52_RS10805	COG2198	Histidine kinase
FKQ52_RS10805	COG2205	protein histidine kinase activity
FKQ52_RS10815	COG2224	Isocitrate lyase
FKQ52_RS10920	COG1733	regulation of RNA biosynthetic process
FKQ52_RS10925	COG2910	NAD(P)H-binding
FKQ52_RS10940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FKQ52_RS10950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FKQ52_RS10960	COG1253	flavin adenine dinucleotide binding
FKQ52_RS10975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKQ52_RS10990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKQ52_RS10995	COG0861	Integral membrane protein TerC family
FKQ52_RS11005	COG0754	glutathionylspermidine amidase activity
FKQ52_RS11020	COG0534	Mate efflux family protein
FKQ52_RS11025	COG0431	NADPH-dependent FMN reductase
FKQ52_RS11030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKQ52_RS11045	COG1024	Enoyl-CoA hydratase
FKQ52_RS11050	COG4770	biotin carboxylase activity
FKQ52_RS11075	COG4106	trans-aconitate 2-methyltransferase activity
FKQ52_RS11095	COG0848	biopolymer transport protein
FKQ52_RS11110	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FKQ52_RS11120	COG0424	maF-like protein
FKQ52_RS11125	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FKQ52_RS11140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FKQ52_RS11195	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS11220	COG0604	alcohol dehydrogenase
FKQ52_RS11225	COG4221	oxidoreductase activity
FKQ52_RS11230	COG1309	transcriptional regulator
FKQ52_RS11245	COG0321	lipoyl(octanoyl) transferase activity
FKQ52_RS11260	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FKQ52_RS11280	COG2239	Acts as a magnesium transporter
FKQ52_RS11290	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS11320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKQ52_RS11325	COG5442	Flagellar protein FlaF
FKQ52_RS11335	COG0859	PFAM glycosyl transferase family 9
FKQ52_RS11335	COG0457	Tetratricopeptide repeat
FKQ52_RS11350	COG0215	cysteine-tRNA ligase activity
FKQ52_RS11355	COG0302	gtp cyclohydrolase
FKQ52_RS11360	COG0848	biopolymer transport protein
FKQ52_RS11365	COG0848	biopolymer transport protein
FKQ52_RS11390	COG4786	Flagellar basal body rod
FKQ52_RS11395	COG4786	Flagellar basal body rod
FKQ52_RS11405	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FKQ52_RS11440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKQ52_RS11450	COG5002	protein histidine kinase activity
FKQ52_RS11455	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS11495	COG0416	fatty acid biosynthetic process
FKQ52_RS11505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKQ52_RS11540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKQ52_RS11550	COG1131	(ABC) transporter
FKQ52_RS11560	COG2986	histidine ammonia-lyase
FKQ52_RS11580	COG0644	oxidoreductase
FKQ52_RS11600	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS11605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKQ52_RS11610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKQ52_RS11625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKQ52_RS11630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKQ52_RS11665	COG3047	cAMP biosynthetic process
FKQ52_RS11670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKQ52_RS11680	COG1294	oxidase, subunit
FKQ52_RS11690	COG4988	ABC transporter
FKQ52_RS11700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKQ52_RS11710	COG1595	DNA-templated transcription, initiation
FKQ52_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS11750	COG0318	PFAM AMP-dependent synthetase and ligase
FKQ52_RS11765	COG2814	Major facilitator Superfamily
FKQ52_RS11780	COG1472	Belongs to the glycosyl hydrolase 3 family
FKQ52_RS11790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FKQ52_RS11795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FKQ52_RS11800	COG0131	Imidazoleglycerol-phosphate dehydratase
FKQ52_RS11800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FKQ52_RS11810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FKQ52_RS11825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKQ52_RS11855	COG0625	glutathione transferase activity
FKQ52_RS11860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FKQ52_RS11865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKQ52_RS11870	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS11885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FKQ52_RS11900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FKQ52_RS11910	COG1496	oxidoreductase activity
FKQ52_RS11915	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FKQ52_RS11925	COG4771	TonB-dependent receptor
FKQ52_RS11930	COG0849	cell division
FKQ52_RS11940	COG1181	Belongs to the D-alanine--D-alanine ligase family
FKQ52_RS11950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FKQ52_RS11960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FKQ52_RS11965	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FKQ52_RS11970	COG1472	Belongs to the glycosyl hydrolase 3 family
FKQ52_RS11980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FKQ52_RS11985	COG0316	Belongs to the HesB IscA family
FKQ52_RS11990	COG0840	transmembrane signaling receptor activity
FKQ52_RS12000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKQ52_RS12020	COG0354	folic acid binding
FKQ52_RS12025	COG0183	Belongs to the thiolase family
FKQ52_RS12075	COG0352	thiamine-phosphate diphosphorylase activity
FKQ52_RS12085	COG2193	ferroxidase activity
FKQ52_RS12095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKQ52_RS12100	COG0483	inositol monophosphate 1-phosphatase activity
FKQ52_RS12105	COG0497	DNA recombination
FKQ52_RS12110	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKQ52_RS12170	COG0012	GTP binding
FKQ52_RS12185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKQ52_RS12185	COG0574	Belongs to the PEP-utilizing enzyme family
FKQ52_RS12205	COG1194	a g-specific adenine glycosylase
FKQ52_RS12240	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FKQ52_RS12285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKQ52_RS12325	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKQ52_RS12335	COG0616	signal peptide processing
FKQ52_RS12340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FKQ52_RS12350	COG2968	Membrane
FKQ52_RS12370	COG1956	GAF domain-containing protein
FKQ52_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS12380	COG2301	Belongs to the HpcH HpaI aldolase family
FKQ52_RS12430	COG2857	Cytochrome c1
FKQ52_RS12430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FKQ52_RS12445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FKQ52_RS12465	COG0408	coproporphyrinogen oxidase activity
FKQ52_RS12470	COG2949	membrane
FKQ52_RS12475	COG2205	protein histidine kinase activity
FKQ52_RS12475	COG2198	Histidine kinase
FKQ52_RS12475	COG0784	Response regulator, receiver
FKQ52_RS12480	COG0519	Catalyzes the synthesis of GMP from XMP
FKQ52_RS12480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKQ52_RS12490	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FKQ52_RS12505	COG1063	alcohol dehydrogenase
FKQ52_RS12510	COG0156	8-amino-7-oxononanoate synthase activity
FKQ52_RS12520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FKQ52_RS12530	COG0018	arginyl-trna synthetase
FKQ52_RS12545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FKQ52_RS12550	COG0509	glycine decarboxylation via glycine cleavage system
FKQ52_RS12560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKQ52_RS12575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FKQ52_RS12580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FKQ52_RS12585	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKQ52_RS12590	COG0356	it plays a direct role in the translocation of protons across the membrane
FKQ52_RS12600	COG2226	methyltransferase
FKQ52_RS12610	COG0142	geranyltranstransferase activity
FKQ52_RS12615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKQ52_RS12620	COG1722	exodeoxyribonuclease VII activity
FKQ52_RS12635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKQ52_RS12690	COG5002	protein histidine kinase activity
FKQ52_RS12700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKQ52_RS12705	COG2204	response regulator
FKQ52_RS12710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKQ52_RS12720	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKQ52_RS12725	COG1766	The M ring may be actively involved in energy transduction
FKQ52_RS12730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKQ52_RS12735	COG1684	flagellar biosynthetic protein fliR
FKQ52_RS12740	COG1987	bacterial-type flagellum assembly
FKQ52_RS12745	COG1846	Transcriptional regulator
FKQ52_RS12755	COG0302	gtp cyclohydrolase
FKQ52_RS12765	COG1677	Flagellar hook-basal body complex protein FliE
FKQ52_RS12770	COG1558	bacterial-type flagellum-dependent cell motility
FKQ52_RS12780	COG3190	flagellar
FKQ52_RS12785	COG1338	Plays a role in the flagellum-specific transport system
FKQ52_RS12790	COG0776	regulation of translation
FKQ52_RS12805	COG2205	protein histidine kinase activity
FKQ52_RS12810	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS12920	COG4942	peptidase
FKQ52_RS13015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FKQ52_RS13025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FKQ52_RS13035	COG0772	Belongs to the SEDS family
FKQ52_RS13045	COG2354	Protein conserved in bacteria
FKQ52_RS13060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FKQ52_RS13095	COG2860	membrane
FKQ52_RS13110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKQ52_RS13115	COG2326	polyphosphate kinase activity
FKQ52_RS13130	COG1278	Cold shock
FKQ52_RS13150	COG0556	nucleotide-excision repair
FKQ52_RS13160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKQ52_RS13170	COG1396	sequence-specific DNA binding
FKQ52_RS13175	COG0730	response to heat
FKQ52_RS13220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKQ52_RS13225	COG1136	(ABC) transporter
FKQ52_RS13245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FKQ52_RS13250	COG0288	reversible hydration of carbon dioxide
FKQ52_RS13260	COG0322	excinuclease ABC activity
FKQ52_RS13265	COG3238	Protein conserved in bacteria
FKQ52_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS13305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKQ52_RS13310	COG0612	Peptidase, M16
FKQ52_RS13320	COG0475	glutathione-regulated potassium exporter activity
FKQ52_RS13320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKQ52_RS13325	COG2304	oxidoreductase activity
FKQ52_RS13330	COG3214	Protein conserved in bacteria
FKQ52_RS13350	COG1012	belongs to the aldehyde dehydrogenase family
FKQ52_RS13355	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FKQ52_RS13365	COG2205	protein histidine kinase activity
FKQ52_RS13365	COG2202	Pas domain
FKQ52_RS13380	COG1595	DNA-templated transcription, initiation
FKQ52_RS13390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FKQ52_RS13395	COG3850	Histidine kinase
FKQ52_RS13395	COG0642	Histidine kinase
FKQ52_RS13410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKQ52_RS13420	COG1138	Cytochrome C-type biogenesis protein
FKQ52_RS13460	COG0384	phenazine biosynthesis protein PhzF
FKQ52_RS13470	COG0351	phosphomethylpyrimidine kinase
FKQ52_RS13480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FKQ52_RS13510	COG0037	tRNA processing
FKQ52_RS13525	COG2885	chlorophyll binding
FKQ52_RS13530	COG0823	Involved in the tonB-independent uptake of proteins
FKQ52_RS13540	COG0848	biopolymer transport protein
FKQ52_RS13555	COG0824	Thioesterase
FKQ52_RS13565	COG2255	four-way junction helicase activity
FKQ52_RS13570	COG0632	four-way junction helicase activity
FKQ52_RS13575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FKQ52_RS13585	COG1285	pathogenesis
FKQ52_RS13605	COG0217	transcriptional regulatory protein
FKQ52_RS13660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FKQ52_RS13665	COG1215	transferase activity, transferring glycosyl groups
FKQ52_RS13705	COG4771	TonB-dependent receptor
FKQ52_RS13710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FKQ52_RS13715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FKQ52_RS13725	COG3655	Transcriptional regulator
FKQ52_RS13745	COG0789	Transcriptional regulator
FKQ52_RS13750	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS13755	COG1960	acyl-CoA dehydrogenase activity
FKQ52_RS13760	COG2161	toxin-antitoxin pair type II binding
FKQ52_RS13765	COG4115	mRNA cleavage
FKQ52_RS13785	COG0784	Response regulator, receiver
FKQ52_RS13785	COG5002	protein histidine kinase activity
FKQ52_RS13810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKQ52_RS13830	COG0167	dihydroorotate dehydrogenase activity
FKQ52_RS13835	COG0784	Response regulator, receiver
FKQ52_RS13835	COG2205	protein histidine kinase activity
FKQ52_RS13840	COG3727	T/G mismatch-specific endonuclease activity
FKQ52_RS13865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKQ52_RS13890	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FKQ52_RS13900	COG0109	protoheme IX farnesyltransferase activity
FKQ52_RS13905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKQ52_RS13930	COG0312	modulator of DNA gyrase
FKQ52_RS13950	COG3104	oligopeptide transport
FKQ52_RS13960	COG1446	asparaginase
FKQ52_RS14020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FKQ52_RS14040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FKQ52_RS14045	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FKQ52_RS14060	COG2205	protein histidine kinase activity
FKQ52_RS14065	COG0745	RESPONSE REGULATOR receiver
FKQ52_RS14075	COG2814	Major facilitator Superfamily
FKQ52_RS14100	COG0587	DNA-directed DNA polymerase activity
FKQ52_RS14125	COG0776	regulation of translation
FKQ52_RS14130	COG0539	negative regulation of cytoplasmic translation
FKQ52_RS14170	COG0071	Belongs to the small heat shock protein (HSP20) family
FKQ52_RS14180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKQ52_RS14185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FKQ52_RS14190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FKQ52_RS14215	COG0443	Heat shock 70 kDa protein
FKQ52_RS14240	COG1137	ATPase activity
FKQ52_RS14255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKQ52_RS14270	COG1968	undecaprenyl-diphosphatase activity
FKQ52_RS14290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FKQ52_RS14295	COG0545	Peptidyl-prolyl cis-trans isomerase
FKQ52_RS14300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FKQ52_RS14325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FKQ52_RS14330	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FKQ52_RS14345	COG1230	cation diffusion facilitator family transporter
FKQ52_RS14355	COG0523	cobalamin synthesis protein
FKQ52_RS14400	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FKQ52_RS14405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKQ52_RS14405	COG2885	chlorophyll binding
FKQ52_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS14415	COG0183	Belongs to the thiolase family
FKQ52_RS14430	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FKQ52_RS14440	COG1877	trehalose-phosphatase activity
FKQ52_RS14465	COG0183	Belongs to the thiolase family
FKQ52_RS14470	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKQ52_RS14470	COG1024	Enoyl-CoA hydratase
FKQ52_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
FKQ52_RS14555	COG2271	Major facilitator Superfamily
FKQ52_RS14570	COG2186	Transcriptional regulator
FKQ52_RS14580	COG0644	oxidoreductase
FKQ52_RS14585	COG0753	catalase activity
FKQ52_RS14600	COG1476	TRANSCRIPTIONal
FKQ52_RS14610	COG1322	Protein conserved in bacteria
FKQ52_RS14625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FKQ52_RS14635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FKQ52_RS14640	COG0778	Nitroreductase
FKQ52_RS14655	COG2816	NAD+ diphosphatase activity
FKQ52_RS14665	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FKQ52_RS14670	COG3474	cytochrome
FKQ52_RS14680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKQ52_RS14690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKQ52_RS14700	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FKQ52_RS14705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FKQ52_RS14710	COG3639	organic phosphonate transmembrane transporter activity
FKQ52_RS14725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FKQ52_RS14730	COG0612	Peptidase, M16
FKQ52_RS14740	COG1899	peptidyl-lysine modification to peptidyl-hypusine
FKQ52_RS14780	COG2885	chlorophyll binding
FKQ52_RS14780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKQ52_RS14855	COG2171	N-acyltransferase activity
FKQ52_RS14860	COG2133	pyrroloquinoline quinone binding
FKQ52_RS14875	COG0693	protein deglycase activity
FKQ52_RS14900	COG3634	alkyl hydroperoxide reductase activity
FKQ52_RS14925	COG1064	alcohol dehydrogenase
FKQ52_RS14935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKQ52_RS14940	COG0165	Argininosuccinate lyase
FKQ52_RS14950	COG0019	diaminopimelate decarboxylase activity
FKQ52_RS14955	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FKQ52_RS14965	COG2884	Cell division ATP-binding protein ftsE
FKQ52_RS14980	COG0204	Acyl-transferase
FKQ52_RS15000	COG1201	RNA secondary structure unwinding
FKQ52_RS15005	COG1199	ATP-dependent helicase activity
FKQ52_RS15025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FKQ52_RS15035	COG0730	response to heat
FKQ52_RS15055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FKQ52_RS15060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKQ52_RS15070	COG0842	Transport permease protein
FKQ52_RS15080	COG2967	ApaG domain
FKQ52_RS15105	COG1473	amidohydrolase
FKQ52_RS15105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FKQ52_RS15150	COG4964	Belongs to the GSP D family
FKQ52_RS15225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FKQ52_RS15230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKQ52_RS15275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FKQ52_RS15300	COG0779	Required for maturation of 30S ribosomal subunits
FKQ52_RS15315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FKQ52_RS15335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FKQ52_RS15340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FKQ52_RS15350	COG1185	polyribonucleotide nucleotidyltransferase activity
FKQ52_RS15375	COG0542	response to heat
FKQ52_RS15420	COG2890	protein-(glutamine-N5) methyltransferase activity
FKQ52_RS15435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKQ52_RS15440	COG0730	response to heat
FKQ52_RS15450	COG0625	glutathione transferase activity
FKQ52_RS15460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FKQ52_RS15465	COG1426	Protein conserved in bacteria
FKQ52_RS15510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKQ52_RS15515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FKQ52_RS15525	COG2226	methyltransferase
FKQ52_RS15535	COG0494	nUDIX hydrolase
FKQ52_RS15540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FKQ52_RS15575	COG0735	belongs to the Fur family
FKQ52_RS15595	COG2130	NADP-dependent
FKQ52_RS15605	COG0784	Response regulator, receiver
FKQ52_RS15640	COG1522	sequence-specific DNA binding
FKQ52_RS15645	COG0686	Belongs to the AlaDH PNT family
FKQ52_RS15670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FKQ52_RS15675	COG0799	negative regulation of ribosome biogenesis
FKQ52_RS15680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FKQ52_RS15685	COG4942	peptidase
FKQ52_RS15690	COG0793	Belongs to the peptidase S41A family
FKQ52_RS15705	COG3813	Protein conserved in bacteria
FKQ52_RS15715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FKQ52_RS15720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FKQ52_RS15725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FKQ52_RS15740	COG1253	flavin adenine dinucleotide binding
FKQ52_RS15755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FKQ52_RS15765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FKQ52_RS15775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKQ52_RS15785	COG0784	Response regulator, receiver
FKQ52_RS15785	COG4191	Histidine kinase
FKQ52_RS15805	COG2095	MarC family integral membrane protein
FKQ52_RS15825	COG0501	Belongs to the peptidase M48B family
FKQ52_RS15835	COG2813	Specifically methylates the guanine in position
FKQ52_RS15840	COG1187	pseudouridine synthase activity
FKQ52_RS15850	COG0135	phosphoribosylanthranilate isomerase activity
FKQ52_RS15855	COG0133	tryptophan synthase activity
FKQ52_RS15865	COG0159	tryptophan synthase activity
FKQ52_RS15885	COG1074	ATP-dependent DNA helicase activity
FKQ52_RS15890	COG2887	Belongs to the helicase family. UvrD subfamily
FKQ52_RS15895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FKQ52_RS15900	COG3178	'Phosphotransferase
FKQ52_RS15905	COG0802	atpase or kinase
FKQ52_RS15915	COG0823	Involved in the tonB-independent uptake of proteins
FKQ52_RS15915	COG1506	peptidase
FKQ52_RS15925	COG2982	Protein involved in outer membrane biogenesis
FKQ52_RS15935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKQ52_RS15970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKQ52_RS15980	COG0840	transmembrane signaling receptor activity
FKQ52_RS15985	COG0835	chemotaxis
FKQ52_RS15995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKQ52_RS16005	COG3655	Transcriptional regulator
FKQ52_RS16015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FKQ52_RS16020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKQ52_RS16025	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FKQ52_RS16040	COG0189	ligase activity
FKQ52_RS16045	COG0606	chelatase, subunit chli
FKQ52_RS16050	COG0784	Response regulator, receiver
FKQ52_RS16050	COG5002	protein histidine kinase activity
FKQ52_RS16050	COG2205	protein histidine kinase activity
FKQ52_RS16055	COG2814	Major facilitator Superfamily
FKQ52_RS16060	COG0281	malic enzyme
FKQ52_RS16060	COG0280	phosphate acetyltransferase
FKQ52_RS16090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKQ52_RS16095	COG1505	serine-type exopeptidase activity
FKQ52_RS16100	COG1505	serine-type exopeptidase activity
FKQ52_RS16110	COG2917	probably involved in intracellular septation
FKQ52_RS16115	COG0552	protein localization to endoplasmic reticulum
FKQ52_RS16125	COG0596	Alpha beta hydrolase
FKQ52_RS16125	COG2945	thiolester hydrolase activity
FKQ52_RS16130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FKQ52_RS16140	COG0673	inositol 2-dehydrogenase activity
FKQ52_RS16155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FKQ52_RS16185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKQ52_RS16195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKQ52_RS16200	COG2824	Alkylphosphonate utilization operon protein PhnA
FKQ52_RS16210	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKQ52_RS16215	COG4133	protoheme IX ABC transporter activity
FKQ52_RS16220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FKQ52_RS16265	COG0300	oxidoreductase activity
FKQ52_RS16270	COG1959	2 iron, 2 sulfur cluster binding
FKQ52_RS16280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKQ52_RS16280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKQ52_RS16295	COG0180	Tryptophanyl-tRNA synthetase