CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 Gene3D G3DSA:3.90.1150.10 314 449 5.9E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 Gene3D G3DSA:3.40.640.10 180 313 6.8E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 PIRSF PIRSF000521 123 389 3.3E-19 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 PIRSF PIRSF000521 408 437 580.0 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 PIRSF PIRSF000521 21 134 1.4E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 Pfam PF00202 Aminotransferase class-III 27 436 1.6E-89 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 SUPERFAMILY SSF53383 5 436 5.62E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS08530 e020f35ba2b23a17fcc0ad58024ea306 454 Gene3D G3DSA:3.90.1150.10 2 168 3.0E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 SUPERFAMILY SSF56784 295 315 3.2E-38 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 SUPERFAMILY SSF56784 395 614 3.2E-38 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 SUPERFAMILY SSF81665 198 291 1.96E-58 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 SUPERFAMILY SSF81665 6 100 1.96E-58 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 SUPERFAMILY SSF81665 583 774 1.96E-58 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 70 480 2.6E-46 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 504 620 4.9E-27 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 Gene3D G3DSA:3.40.1110.10 237 436 2.5E-22 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 Gene3D G3DSA:3.40.50.1000 437 560 8.4E-22 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 Pfam PF00122 E1-E2 ATPase 97 276 1.5E-41 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 Gene3D G3DSA:1.20.1110.10 561 776 3.1E-21 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 435 446 2.1E-22 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 147 161 2.1E-22 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 467 2.1E-22 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 2.1E-22 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 297 311 2.1E-22 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 2.1E-22 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 299 305 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 SUPERFAMILY SSF81653 100 193 6.28E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 565 590 8.5E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 398 416 8.5E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 534 550 8.5E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 Pfam PF00702 haloacid dehalogenase-like hydrolase 294 548 1.5E-25 T 28-03-2018 CPF12_RS00065 d7cfef5f5774b9b40ac1f834ac4611b3 777 Gene3D G3DSA:2.70.150.10 2 196 3.0E-31 T 28-03-2018 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 68 205 1.4E-25 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 SMART SM00047 50 209 3.0E-47 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 Gene3D G3DSA:1.10.530.10 52 207 3.3E-40 T 28-03-2018 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 PRINTS PR01002 Flagellar protein FlgJ signature 186 204 6.3E-12 T 28-03-2018 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 PRINTS PR01002 Flagellar protein FlgJ signature 81 99 6.3E-12 T 28-03-2018 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 PRINTS PR01002 Flagellar protein FlgJ signature 166 185 6.3E-12 T 28-03-2018 CPF12_RS09815 3636e799691b8900d64e0c92c74e1cf3 209 PRINTS PR01002 Flagellar protein FlgJ signature 57 80 6.3E-12 T 28-03-2018 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 SUPERFAMILY SSF48150 1 210 3.61E-73 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 1.3E-25 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 PIRSF PIRSF001435 1 214 1.3E-59 T 28-03-2018 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 7.8E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 Gene3D G3DSA:1.10.1670.10 118 216 8.7E-34 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 TIGRFAM TIGR01083 nth: endonuclease III 4 196 7.1E-83 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 SMART SM00525 188 208 6.0E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 Gene3D G3DSA:1.10.340.30 26 117 1.3E-29 T 28-03-2018 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 Hamap MF_00942 Endonuclease III [nth]. 1 211 37.794 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 SMART SM00478 39 187 3.8E-63 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS10350 30cce59b08085b96d188980d21f0c014 219 Pfam PF00633 Helix-hairpin-helix motif 101 128 2.6E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Gene3D G3DSA:3.30.70.1430 568 699 0.055 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82693 279 331 2.14E-15 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82693 134 180 2.14E-15 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Gene3D G3DSA:1.20.1640.10 812 1028 1.7E-39 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82693 41 132 1.92E-19 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 450 473 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 475 498 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 9.1E-47 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Gene3D G3DSA:3.30.70.1430 41 140 8.2E-23 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Pfam PF00873 AcrB/AcrD/AcrF family 5 1014 5.8E-205 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82866 799 1020 2.09E-44 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Gene3D G3DSA:1.20.1640.10 279 504 5.5E-46 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82714 184 249 6.28E-6 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82714 714 796 3.14E-8 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 SUPERFAMILY SSF82866 301 501 2.09E-43 T 28-03-2018 CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Gene3D G3DSA:3.30.2090.10 709 800 6.8E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CPF12_RS07540 36b7f8b38c86d229ae3178bfe48d648f 1028 Gene3D G3DSA:3.30.2090.10 180 278 2.4E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CPF12_RS02245 e1b9e3c09637fba0eed4a172d49c4ecb 200 Pfam PF08006 Protein of unknown function (DUF1700) 1 185 4.3E-24 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CPF12_RS00560 82281f39dc22bcf4ef05c72ebb4a2a65 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS00560 82281f39dc22bcf4ef05c72ebb4a2a65 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS00560 82281f39dc22bcf4ef05c72ebb4a2a65 207 SUPERFAMILY SSF46689 13 72 6.98E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS00560 82281f39dc22bcf4ef05c72ebb4a2a65 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS00560 82281f39dc22bcf4ef05c72ebb4a2a65 207 Gene3D G3DSA:1.10.10.60 11 54 1.8E-13 T 28-03-2018 CPF12_RS00560 82281f39dc22bcf4ef05c72ebb4a2a65 207 Gene3D G3DSA:1.10.10.60 55 190 2.8E-8 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 ProSitePatterns PS01047 Heavy-metal-associated domain. 77 106 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 4 29 1.4E-14 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 210 235 1.4E-14 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 30 53 1.4E-14 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Gene3D G3DSA:3.30.70.100 70 158 3.6E-20 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Gene3D G3DSA:1.20.1110.10 260 512 1.9E-42 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF81653 299 395 4.45E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF55008 2 70 3.01E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Pfam PF00122 E1-E2 ATPase 296 476 9.8E-55 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 136 2.4E-8 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 69 1.0E-11 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF55008 74 140 5.5E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Gene3D G3DSA:3.40.1110.10 513 621 3.8E-33 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Pfam PF00403 Heavy-metal-associated domain 75 135 8.1E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Pfam PF00403 Heavy-metal-associated domain 6 67 4.2E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Gene3D G3DSA:3.30.70.100 3 69 4.9E-20 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF56784 495 515 4.01E-63 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF56784 554 796 4.01E-63 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 268 785 9.3E-92 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF81665 396 491 4.32E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF81665 264 299 4.32E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 SUPERFAMILY SSF81665 745 777 4.32E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Pfam PF00702 haloacid dehalogenase-like hydrolase 494 710 3.2E-46 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 653 1.9E-28 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 1.9E-28 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 632 1.9E-28 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 696 715 1.9E-28 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 719 731 1.9E-28 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 511 1.9E-28 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 208 799 1.9E-181 T 28-03-2018 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 499 505 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 227 798 1.0E-195 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS07515 f24cb3124312313999cf5e0867a0780e 805 Gene3D G3DSA:3.40.50.1000 622 762 1.3E-45 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 PRINTS PR00988 Uridine kinase signature 136 146 1.2E-36 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 PRINTS PR00988 Uridine kinase signature 35 46 1.2E-36 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 PRINTS PR00988 Uridine kinase signature 5 22 1.2E-36 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 PRINTS PR00988 Uridine kinase signature 80 95 1.2E-36 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 PRINTS PR00988 Uridine kinase signature 172 185 1.2E-36 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 PRINTS PR00988 Uridine kinase signature 150 161 1.2E-36 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 Gene3D G3DSA:3.40.50.300 1 209 5.3E-61 T 28-03-2018 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 SUPERFAMILY SSF52540 4 198 1.32E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 Hamap MF_00551 Uridine kinase [udk]. 2 206 40.746 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 193 6.9E-46 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CPF12_RS09700 179449806b5044f3972f5eed1012b5fb 209 TIGRFAM TIGR00235 udk: uridine kinase 3 205 1.1E-86 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 1.6E-41 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 1.6E-41 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 1.6E-41 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 1.6E-41 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 1.6E-41 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 Pfam PF00334 Nucleoside diphosphate kinase 2 135 2.0E-50 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 32.404 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 Gene3D G3DSA:3.30.70.141 1 52 2.2E-15 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 Gene3D G3DSA:3.30.70.141 53 137 2.0E-31 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 SMART SM00562 1 137 5.9E-67 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS09510 02d031763e85554c5d6f815645ed888b 137 SUPERFAMILY SSF54919 1 136 8.25E-54 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS10450 b6a1bb7bcd331c402a9321fa9fbb9b34 127 Pfam PF07972 NrdI Flavodoxin like 3 113 9.1E-30 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CPF12_RS10450 b6a1bb7bcd331c402a9321fa9fbb9b34 127 PIRSF PIRSF005087 1 126 7.4E-33 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CPF12_RS10450 b6a1bb7bcd331c402a9321fa9fbb9b34 127 Gene3D G3DSA:3.40.50.360 1 123 2.7E-12 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS10450 b6a1bb7bcd331c402a9321fa9fbb9b34 127 SUPERFAMILY SSF52218 1 120 1.15E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS11440 ecd250e9f168dd14fda770e184b2e8e7 71 Gene3D G3DSA:3.90.940.10 2 70 1.3E-19 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CPF12_RS11440 ecd250e9f168dd14fda770e184b2e8e7 71 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 61 1.4E-17 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS11440 ecd250e9f168dd14fda770e184b2e8e7 71 Pfam PF01192 RNA polymerase Rpb6 10 61 1.3E-12 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CPF12_RS11440 ecd250e9f168dd14fda770e184b2e8e7 71 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 64 13.6 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS11440 ecd250e9f168dd14fda770e184b2e8e7 71 SUPERFAMILY SSF63562 2 65 3.14E-19 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CPF12_RS11440 ecd250e9f168dd14fda770e184b2e8e7 71 SMART SM01409 9 63 2.3E-12 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CPF12_RS07000 97e08bde62086a5901d2d87a9eda9d9d 308 SMART SM01131 181 307 6.4E-47 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CPF12_RS07000 97e08bde62086a5901d2d87a9eda9d9d 308 Pfam PF01368 DHH family 3 146 2.4E-27 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CPF12_RS07000 97e08bde62086a5901d2d87a9eda9d9d 308 Gene3D G3DSA:3.90.1640.10 1 188 1.4E-64 T 28-03-2018 CPF12_RS07000 97e08bde62086a5901d2d87a9eda9d9d 308 Pfam PF02833 DHHA2 domain 183 304 1.4E-16 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CPF12_RS07000 97e08bde62086a5901d2d87a9eda9d9d 308 SUPERFAMILY SSF64182 3 304 1.09E-77 T 28-03-2018 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.8E-46 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 PIRSF PIRSF000183 1 370 7.4E-176 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 Gene3D G3DSA:3.40.50.720 1 176 6.8E-44 T 28-03-2018 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 Gene3D G3DSA:3.40.50.720 194 371 2.4E-41 T 28-03-2018 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 SUPERFAMILY SSF51735 136 303 3.16E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 SMART SM01002 148 297 1.4E-84 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 SUPERFAMILY SSF52283 305 358 3.91E-63 T 28-03-2018 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 SUPERFAMILY SSF52283 1 136 3.91E-63 T 28-03-2018 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 Gene3D G3DSA:3.50.50.60 177 193 0.0011 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 SMART SM01003 4 136 5.4E-75 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.1E-78 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CPF12_RS12070 3d7ad3a3702fb11bc9259d47c57639e4 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 368 1.5E-169 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CPF12_RS11680 6eab0acfb5f66c827f5ef5de0b923bd1 305 Gene3D G3DSA:3.40.50.300 3 285 2.5E-55 T 28-03-2018 CPF12_RS11680 6eab0acfb5f66c827f5ef5de0b923bd1 305 Pfam PF00005 ABC transporter 22 162 7.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11680 6eab0acfb5f66c827f5ef5de0b923bd1 305 SMART SM00382 31 212 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11680 6eab0acfb5f66c827f5ef5de0b923bd1 305 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11680 6eab0acfb5f66c827f5ef5de0b923bd1 305 SUPERFAMILY SSF52540 4 230 8.36E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Pfam PF00005 ABC transporter 19 195 1.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Pfam PF00005 ABC transporter 347 476 1.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 SMART SM00382 28 247 2.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 SMART SM00382 355 521 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 SUPERFAMILY SSF52540 316 536 4.17E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Gene3D G3DSA:3.40.50.300 331 577 3.9E-48 T 28-03-2018 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Gene3D G3DSA:1.20.58.410 578 642 5.1E-6 T 28-03-2018 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Gene3D G3DSA:3.40.50.300 2 276 1.5E-53 T 28-03-2018 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 ProSitePatterns PS00211 ABC transporters family signature. 448 462 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Pfam PF16326 ABC transporter C-terminal domain 577 642 9.0E-12 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 SUPERFAMILY SSF52540 4 248 6.03E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02235 a540363911d5b9c4cc24bda8e873a657 642 Pfam PF12848 ABC transporter 235 317 9.5E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain CPF12_RS08705 004c876f815821655509a9289819f1cd 477 Gene3D G3DSA:3.60.20.10 12 239 3.4E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS08705 004c876f815821655509a9289819f1cd 477 Gene3D G3DSA:3.40.50.2020 240 437 1.0E-32 T 28-03-2018 CPF12_RS08705 004c876f815821655509a9289819f1cd 477 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 456 45.911 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CPF12_RS08705 004c876f815821655509a9289819f1cd 477 Pfam PF13537 Glutamine amidotransferase domain 93 208 1.3E-20 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CPF12_RS08705 004c876f815821655509a9289819f1cd 477 SUPERFAMILY SSF56235 12 237 6.0E-69 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS08705 004c876f815821655509a9289819f1cd 477 Pfam PF00156 Phosphoribosyl transferase domain 278 381 1.5E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CPF12_RS08705 004c876f815821655509a9289819f1cd 477 PIRSF PIRSF000485 8 472 1.9E-175 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CPF12_RS08705 004c876f815821655509a9289819f1cd 477 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 457 5.5E-160 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CPF12_RS08705 004c876f815821655509a9289819f1cd 477 SUPERFAMILY SSF53271 246 465 6.95E-73 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SUPERFAMILY SSF89000 832 1009 3.33E-55 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SUPERFAMILY SSF51246 339 457 7.32E-40 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Pfam PF02436 Conserved carboxylase domain 827 1026 2.3E-71 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Pfam PF00682 HMGL-like 532 781 1.9E-22 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Pfam PF02785 Biotin carboxylase C-terminal domain 344 451 3.8E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Pfam PF00364 Biotin-requiring enzyme 1080 1143 3.3E-15 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 6 1143 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SMART SM00878 344 451 6.6E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:3.30.1490.20 127 212 9.5E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:2.40.50.100 1075 1144 5.5E-17 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 PIRSF PIRSF001594 1 1144 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 110 4.0E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:3.30.470.20 213 453 1.9E-91 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 322 1.4E-76 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:3.10.600.10 989 1060 1.6E-19 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SUPERFAMILY SSF51569 524 835 3.48E-78 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SUPERFAMILY SSF56059 86 354 1.03E-65 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:3.20.20.70 533 819 3.7E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SUPERFAMILY SSF51230 1069 1143 4.97E-19 T 28-03-2018 IPR011053 Single hybrid motif CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:3.10.600.10 463 532 1.3E-17 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:1.10.10.60 943 988 6.6E-16 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 Gene3D G3DSA:3.40.50.20 3 126 2.5E-49 T 28-03-2018 CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 SUPERFAMILY SSF52440 2 113 7.91E-44 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS02115 73fb88cc68060e0e8f3c43f259274e9a 1144 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 Gene3D G3DSA:1.10.357.10 69 197 1.3E-4 T 28-03-2018 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 Gene3D G3DSA:1.10.10.60 1 39 1.6E-13 T 28-03-2018 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 7.7E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 Gene3D G3DSA:1.10.260.40 40 68 6.6E-10 T 28-03-2018 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10370 fd68235bb52fb47a9ef60eee1f7b6d28 198 SUPERFAMILY SSF46689 8 80 1.08E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SUPERFAMILY SSF52540 6 279 8.01E-110 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06040 926f63622244646376f774645c9a1f40 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 1.9E-42 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Gene3D G3DSA:3.40.50.300 1 285 4.8E-62 T 28-03-2018 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Pfam PF03764 Elongation factor G, domain IV 476 594 6.0E-43 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Gene3D G3DSA:3.30.70.240 611 688 6.4E-31 T 28-03-2018 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SUPERFAMILY SSF50447 263 401 4.54E-36 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SUPERFAMILY SSF54211 476 596 1.49E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Pfam PF03144 Elongation factor Tu domain 2 321 388 8.4E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Pfam PF00679 Elongation factor G C-terminus 598 683 3.2E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SUPERFAMILY SSF54980 600 687 3.36E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS06040 926f63622244646376f774645c9a1f40 691 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.0E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.0E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.0E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.0E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.0E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SMART SM00889 477 595 9.4E-67 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 1.8E-68 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SMART SM00838 597 684 5.3E-55 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CPF12_RS06040 926f63622244646376f774645c9a1f40 691 SUPERFAMILY SSF54980 399 477 3.17E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS06040 926f63622244646376f774645c9a1f40 691 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Pfam PF14492 Elongation Factor G, domain II 401 474 4.3E-36 T 28-03-2018 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Gene3D G3DSA:2.40.30.10 288 396 1.5E-30 T 28-03-2018 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Gene3D G3DSA:3.30.230.10 489 610 5.7E-40 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Gene3D G3DSA:3.30.70.870 397 488 1.1E-35 T 28-03-2018 CPF12_RS06040 926f63622244646376f774645c9a1f40 691 Hamap MF_00054_B Elongation factor G [fusA]. 6 688 109.924 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS07565 9a44558367994f0683bd495fd365af35 61 SMART SM00530 4 57 7.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS07565 9a44558367994f0683bd495fd365af35 61 Pfam PF01381 Helix-turn-helix 6 49 5.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS07565 9a44558367994f0683bd495fd365af35 61 Gene3D G3DSA:3.30.1190.10 23 56 1.7E-8 T 28-03-2018 CPF12_RS07565 9a44558367994f0683bd495fd365af35 61 SUPERFAMILY SSF47413 2 60 3.49E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS07565 9a44558367994f0683bd495fd365af35 61 Gene3D G3DSA:1.10.10.10 1 22 7.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 Gene3D G3DSA:1.10.260.40 3 56 3.7E-25 T 28-03-2018 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 Gene3D G3DSA:3.40.50.2300 57 175 1.4E-32 T 28-03-2018 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 Gene3D G3DSA:3.40.50.2300 176 314 1.3E-32 T 28-03-2018 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 8.7E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 332 4.8E-153 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 SUPERFAMILY SSF53822 62 332 7.07E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 SUPERFAMILY SSF47413 2 60 4.93E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 Pfam PF13377 Periplasmic binding protein-like domain 170 331 1.1E-28 T 28-03-2018 CPF12_RS09920 d294d1f1aef3158f331cec75dc3dde7e 332 SMART SM00354 2 72 1.9E-38 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS05265 81a4b1a97e939fff758a13e51a383f94 567 Gene3D G3DSA:3.40.50.1700 384 558 6.9E-6 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS05265 81a4b1a97e939fff758a13e51a383f94 567 SUPERFAMILY SSF51445 35 373 4.32E-66 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS05265 81a4b1a97e939fff758a13e51a383f94 567 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 41 360 3.2E-63 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS05265 81a4b1a97e939fff758a13e51a383f94 567 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 283 300 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CPF12_RS05265 81a4b1a97e939fff758a13e51a383f94 567 Gene3D G3DSA:3.20.20.300 24 383 5.9E-67 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Gene3D G3DSA:3.90.320.10 969 1243 4.7E-36 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Pfam PF00580 UvrD/REP helicase N-terminal domain 26 482 6.9E-78 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Gene3D G3DSA:3.40.50.300 496 647 6.6E-24 T 28-03-2018 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Gene3D G3DSA:1.10.486.10 648 792 3.3E-38 T 28-03-2018 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 23 1243 18.547 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1070 1234 2.1E-9 T 28-03-2018 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Pfam PF13361 UvrD-like helicase C-terminal domain 493 904 7.7E-37 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 Gene3D G3DSA:3.40.50.300 19 495 1.8E-50 T 28-03-2018 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 SUPERFAMILY SSF52980 1031 1240 3.81E-26 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 SUPERFAMILY SSF52540 881 907 6.25E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 SUPERFAMILY SSF52540 361 839 6.25E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 SUPERFAMILY SSF52540 19 196 6.25E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02810 871c018b2261bd86f9fd0ce8804f54e9 1243 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 25 1242 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 SUPERFAMILY SSF52255 4 159 7.46E-69 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 6.4E-69 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 SMART SM01001 3 154 6.8E-106 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 Gene3D G3DSA:3.40.50.7700 1 162 3.4E-70 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 Pfam PF00731 AIR carboxylase 4 152 6.5E-68 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 PIRSF PIRSF001338 1 162 2.4E-72 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CPF12_RS08670 663234b1639b43ef3cb23587cd064eab 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 34.218 T 28-03-2018 IPR033747 Class I PurE CPF12_RS08215 09cbbaff4948374ba4194c5e0fc5c021 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 61 1.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS08215 09cbbaff4948374ba4194c5e0fc5c021 213 SUPERFAMILY SSF46689 4 67 2.57E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS08215 09cbbaff4948374ba4194c5e0fc5c021 213 Gene3D G3DSA:1.10.10.60 48 154 5.8E-8 T 28-03-2018 CPF12_RS08215 09cbbaff4948374ba4194c5e0fc5c021 213 Gene3D G3DSA:1.10.10.60 2 47 1.4E-15 T 28-03-2018 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 Pfam PF00203 Ribosomal protein S19 3 83 4.8E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 PIRSF PIRSF002144 1 91 1.0E-30 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 SUPERFAMILY SSF54570 3 84 7.19E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 90 2.0E-44 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 Gene3D G3DSA:3.30.860.10 1 91 1.6E-39 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.3E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.3E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.3E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.133 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06080 7786ed551078b746f894ed5ed4b2e03f 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 Gene3D G3DSA:3.40.50.2300 175 310 1.7E-26 T 28-03-2018 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 Gene3D G3DSA:3.40.50.2300 65 174 8.5E-13 T 28-03-2018 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 SUPERFAMILY SSF47413 13 71 1.41E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 Gene3D G3DSA:1.10.260.40 12 64 1.3E-19 T 28-03-2018 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 3.0E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 28-03-2018 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 SMART SM00354 13 83 2.8E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 Pfam PF13377 Periplasmic binding protein-like domain 168 324 4.2E-24 T 28-03-2018 CPF12_RS07755 7d79eba7f096fa4fec312fc04f241fe2 341 SUPERFAMILY SSF53822 70 325 1.54E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 Gene3D G3DSA:3.90.1150.10 1 145 5.3E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 379 3.0E-139 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 380 43.064 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 SUPERFAMILY SSF53383 4 380 3.63E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 Gene3D G3DSA:3.40.640.10 149 276 3.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 Pfam PF00202 Aminotransferase class-III 9 379 1.8E-115 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 Gene3D G3DSA:3.90.1150.10 277 381 3.5E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 PIRSF PIRSF000521 106 144 0.0076 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 PIRSF PIRSF000521 155 382 1.8E-36 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 PIRSF PIRSF000521 6 112 1.3E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS02305 ee639efb4e8aa8db296abae3c18de275 387 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 206 243 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 SUPERFAMILY SSF56420 2 178 9.29E-58 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 Pfam PF01327 Polypeptide deformylase 4 171 1.0E-42 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 Gene3D G3DSA:3.90.45.10 3 183 1.2E-49 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.131 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 PRINTS PR01576 Peptide deformylase signature 121 139 3.1E-29 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 PRINTS PR01576 Peptide deformylase signature 108 119 3.1E-29 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 PRINTS PR01576 Peptide deformylase signature 47 76 3.1E-29 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 PRINTS PR01576 Peptide deformylase signature 140 169 3.1E-29 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 PIRSF PIRSF004749 2 183 2.3E-43 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS02210 9a759ff1ee9b2e9553be5b0028e713c9 183 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 177 5.0E-43 T 28-03-2018 IPR023635 Peptide deformylase CPF12_RS11835 d2ff44680fcdd80a1f4d6281f3dd40ec 203 Pfam PF02660 Glycerol-3-phosphate acyltransferase 13 186 2.0E-51 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CPF12_RS11835 d2ff44680fcdd80a1f4d6281f3dd40ec 203 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 9 195 19.863 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CPF12_RS11835 d2ff44680fcdd80a1f4d6281f3dd40ec 203 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 7 195 1.0E-59 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CPF12_RS11835 d2ff44680fcdd80a1f4d6281f3dd40ec 203 SMART SM01207 12 187 1.6E-76 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 SUPERFAMILY SSF143034 2 62 3.53E-21 T 28-03-2018 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.456 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.2E-21 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.2E-21 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.2E-21 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 Pfam PF01632 Ribosomal protein L35 2 61 2.5E-23 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02510 7a4a99a654b0241b8ddbb5a86aa18798 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.3E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 233 248 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 Gene3D G3DSA:3.10.20.70 1 103 2.4E-36 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 4.1E-33 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 440 4.9E-176 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 Gene3D G3DSA:3.30.590.10 104 443 6.5E-125 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 Pfam PF00120 Glutamine synthetase, catalytic domain 105 439 3.7E-136 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 SUPERFAMILY SSF54368 4 103 2.09E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 SMART SM01230 104 353 4.8E-135 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 SUPERFAMILY SSF55931 105 441 1.18E-124 T 28-03-2018 CPF12_RS11865 b5e00f280c4bc25add36b0c450b2347e 443 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 360 372 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CPF12_RS05790 03a317e1836369b5687443d8267a5fad 85 SMART SM00363 5 65 2.5E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS05790 03a317e1836369b5687443d8267a5fad 85 Pfam PF01479 S4 domain 5 51 2.9E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS05790 03a317e1836369b5687443d8267a5fad 85 SUPERFAMILY SSF55174 4 80 7.85E-21 T 28-03-2018 CPF12_RS05790 03a317e1836369b5687443d8267a5fad 85 Gene3D G3DSA:3.10.290.10 1 85 1.6E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS05790 03a317e1836369b5687443d8267a5fad 85 PIRSF PIRSF038881 5 85 1.4E-31 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type CPF12_RS10625 1dea9870be6c81cfbb59a34a0dfaabfa 235 Pfam PF01048 Phosphorylase superfamily 16 230 3.4E-40 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS10625 1dea9870be6c81cfbb59a34a0dfaabfa 235 Gene3D G3DSA:3.40.50.1580 8 235 5.0E-54 T 28-03-2018 CPF12_RS10625 1dea9870be6c81cfbb59a34a0dfaabfa 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10625 1dea9870be6c81cfbb59a34a0dfaabfa 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 46.249 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CPF12_RS10625 1dea9870be6c81cfbb59a34a0dfaabfa 235 SUPERFAMILY SSF53167 2 233 8.12E-86 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS10625 1dea9870be6c81cfbb59a34a0dfaabfa 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 3.3E-99 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 Gene3D G3DSA:3.40.50.300 288 530 1.7E-57 T 28-03-2018 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 Gene3D G3DSA:3.40.50.300 3 244 2.8E-53 T 28-03-2018 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 SUPERFAMILY SSF52540 6 233 2.61E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 SUPERFAMILY SSF52540 285 521 1.22E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 Pfam PF00005 ABC transporter 25 171 4.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 Pfam PF00005 ABC transporter 310 453 4.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 SMART SM00382 31 228 3.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07310 63b5b1687ff163323379c6c613a914b0 551 SMART SM00382 319 504 1.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 SMART SM01061 1 59 2.5E-23 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 Gene3D G3DSA:1.10.1790.10 166 277 2.8E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 Gene3D G3DSA:1.10.1790.10 56 165 6.6E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 Gene3D G3DSA:2.30.24.10 1 55 2.4E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 SUPERFAMILY SSF50151 1 54 1.83E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 Pfam PF03123 CAT RNA binding domain 1 56 4.0E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 SUPERFAMILY SSF63520 171 273 5.49E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 Pfam PF00874 PRD domain 77 163 7.8E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 Pfam PF00874 PRD domain 181 272 4.0E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04755 ed86dae4cefc17d2ed7b7f4f52141102 277 SUPERFAMILY SSF63520 57 166 9.55E-28 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Pfam PF01624 MutS domain I 4 114 2.2E-43 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Gene3D G3DSA:3.30.420.110 128 251 1.3E-22 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 3 875 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 SUPERFAMILY SSF53150 113 268 1.44E-31 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Gene3D G3DSA:3.40.1170.10 1 127 2.2E-45 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 SMART SM00534 599 786 2.9E-110 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Pfam PF05192 MutS domain III 261 550 2.0E-44 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 SUPERFAMILY SSF48334 256 555 2.22E-89 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 680 696 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Pfam PF05190 MutS family domain IV 418 509 1.3E-30 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 SMART SM00533 273 582 3.5E-106 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 PIRSF PIRSF037677 1 836 1.9E-163 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 SUPERFAMILY SSF55271 2 111 1.09E-40 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Pfam PF05188 MutS domain II 124 242 5.9E-15 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 3 870 25.187 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Gene3D G3DSA:1.10.1420.10 252 397 7.4E-38 T 28-03-2018 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Pfam PF00488 MutS domain V 603 789 8.7E-81 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 SUPERFAMILY SSF52540 558 790 4.58E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Gene3D G3DSA:3.40.50.300 558 833 2.1E-43 T 28-03-2018 CPF12_RS11900 9b495c1e9ae8c87a95926148c6984bd1 882 Gene3D G3DSA:1.10.1420.10 398 526 7.3E-31 T 28-03-2018 CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 Pfam PF00411 Ribosomal protein S11 19 128 1.7E-50 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 1.2E-58 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 PIRSF PIRSF002131 1 129 1.4E-53 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 SUPERFAMILY SSF53137 14 129 4.36E-49 T 28-03-2018 CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 Gene3D G3DSA:3.30.420.80 5 129 4.7E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06185 f311bddf0a82a8558198a9ae651d444e 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.25 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CPF12_RS10250 eb73728f912aca845d5a87b41708356f 244 Gene3D G3DSA:3.40.50.880 7 214 4.7E-16 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS10250 eb73728f912aca845d5a87b41708356f 244 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 5 198 3.0E-45 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CPF12_RS10250 eb73728f912aca845d5a87b41708356f 244 SUPERFAMILY SSF52317 20 191 5.59E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 SUPERFAMILY SSF55874 16 227 3.41E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 16 646 2.6E-304 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 574 635 1.4E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Pfam PF00204 DNA gyrase B 233 402 1.5E-62 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 43 184 6.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 SMART SM00433 45 639 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Gene3D G3DSA:3.30.230.10 237 404 5.3E-62 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 516 533 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 123 137 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 80 93 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 578 594 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 536 548 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 498 514 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 45 60 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 280 293 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR00418 DNA topoisomerase II family signature 432 446 8.6E-72 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 13 646 91.672 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 SMART SM00387 41 185 6.5E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 615 631 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 372 386 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 324 340 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 482 491 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 16 26 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 191 206 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 386 406 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 206 219 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 599 611 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 PRINTS PR01159 DNA gyrase subunit B signature 232 254 1.8E-71 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Gene3D G3DSA:3.30.565.10 26 236 4.1E-75 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Pfam PF01751 Toprim domain 431 542 5.8E-18 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 SUPERFAMILY SSF54211 233 403 3.79E-59 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 ProSitePatterns PS00177 DNA topoisomerase II signature. 434 442 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 Gene3D G3DSA:3.40.50.670 411 643 2.2E-102 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05530 b9955363376d3b6672368ae4666695f0 646 SUPERFAMILY SSF56719 406 638 7.32E-91 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CPF12_RS07265 9ee713c3811b0f406456ec890205ee30 462 Pfam PF13347 MFS/sugar transport protein 17 443 9.9E-100 T 28-03-2018 CPF12_RS07265 9ee713c3811b0f406456ec890205ee30 462 SUPERFAMILY SSF103473 18 441 3.14E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS07265 9ee713c3811b0f406456ec890205ee30 462 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 66 91 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 CPF12_RS07265 9ee713c3811b0f406456ec890205ee30 462 Gene3D G3DSA:1.20.1250.20 16 220 2.9E-16 T 28-03-2018 CPF12_RS07265 9ee713c3811b0f406456ec890205ee30 462 Gene3D G3DSA:1.20.1250.20 221 447 8.0E-16 T 28-03-2018 CPF12_RS07265 9ee713c3811b0f406456ec890205ee30 462 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 15 453 6.6E-109 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CPF12_RS02910 019d932512a4c0c59b3c286541a6a2f0 284 Gene3D G3DSA:3.30.2350.10 81 284 5.6E-32 T 28-03-2018 CPF12_RS02910 019d932512a4c0c59b3c286541a6a2f0 284 SUPERFAMILY SSF55120 76 282 3.6E-35 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS02910 019d932512a4c0c59b3c286541a6a2f0 284 Pfam PF00849 RNA pseudouridylate synthase 90 238 1.1E-19 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Gene3D G3DSA:3.10.20.320 204 273 7.4E-11 T 28-03-2018 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Gene3D G3DSA:3.10.20.320 340 420 6.6E-15 T 28-03-2018 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Gene3D G3DSA:3.10.20.320 128 203 2.2E-5 T 28-03-2018 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Gene3D G3DSA:3.10.20.320 51 127 1.4E-10 T 28-03-2018 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Gene3D G3DSA:3.10.20.320 274 339 5.7E-10 T 28-03-2018 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 432 460 5.3E-4 T 28-03-2018 CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Pfam PF06458 MucBP domain 66 118 7.9E-7 T 28-03-2018 IPR009459 MucBP domain CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Pfam PF06458 MucBP domain 277 333 3.5E-8 T 28-03-2018 IPR009459 MucBP domain CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Pfam PF06458 MucBP domain 346 405 1.9E-9 T 28-03-2018 IPR009459 MucBP domain CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Pfam PF06458 MucBP domain 136 195 0.0012 T 28-03-2018 IPR009459 MucBP domain CPF12_RS01840 efa1447ddd5160601aba3b04846ed208 471 Pfam PF06458 MucBP domain 214 265 7.4E-5 T 28-03-2018 IPR009459 MucBP domain CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 SMART SM00382 56 227 1.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 Gene3D G3DSA:3.30.250.10 268 324 5.0E-23 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 322 2.5E-172 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 SUPERFAMILY SSF52540 2 266 3.47E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 Gene3D G3DSA:3.40.50.300 25 267 8.6E-46 T 28-03-2018 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 PRINTS PR00142 RecA protein signature 92 121 3.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 PRINTS PR00142 RecA protein signature 242 271 3.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 PRINTS PR00142 RecA protein signature 126 155 3.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 PRINTS PR00142 RecA protein signature 209 237 3.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 PRINTS PR00142 RecA protein signature 296 313 3.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 PRINTS PR00142 RecA protein signature 164 193 3.4E-84 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 Hamap MF_00268 Protein RecA [recA]. 4 328 52.913 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 SUPERFAMILY SSF54752 267 325 5.23E-20 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 ProSitePatterns PS00321 recA signature. 212 220 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CPF12_RS00010 3b50f54ef59619867f837ebee2393ac1 350 Pfam PF00154 recA bacterial DNA recombination protein 7 267 1.2E-145 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CPF12_RS06810 d82c778074542f0197ffb3ee037f0c64 321 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 10 315 3.6E-114 T 28-03-2018 IPR010119 Gluconeogenesis factor CPF12_RS06810 d82c778074542f0197ffb3ee037f0c64 321 Gene3D G3DSA:3.40.50.10680 87 321 1.7E-58 T 28-03-2018 CPF12_RS06810 d82c778074542f0197ffb3ee037f0c64 321 SUPERFAMILY SSF142338 7 311 1.19E-96 T 28-03-2018 CPF12_RS06810 d82c778074542f0197ffb3ee037f0c64 321 Hamap MF_00973 Gluconeogenesis factor. 6 317 34.909 T 28-03-2018 IPR010119 Gluconeogenesis factor CPF12_RS06810 d82c778074542f0197ffb3ee037f0c64 321 Pfam PF01933 Uncharacterised protein family UPF0052 10 274 5.1E-96 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CPF12_RS00020 3d455c24c26a1c658ea0ae358f6ae1a0 193 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 186 6.9E-58 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CPF12_RS00020 3d455c24c26a1c658ea0ae358f6ae1a0 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 4.3E-17 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CPF12_RS00020 3d455c24c26a1c658ea0ae358f6ae1a0 193 PIRSF PIRSF000847 1 193 1.3E-50 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CPF12_RS00020 3d455c24c26a1c658ea0ae358f6ae1a0 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 SUPERFAMILY SSF52440 5 104 6.62E-29 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 SUPERFAMILY SSF56059 106 304 3.01E-61 T 28-03-2018 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 Gene3D G3DSA:3.30.1490.20 121 184 3.1E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 359 43.387 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 362 5.5E-124 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 SUPERFAMILY SSF51246 309 372 3.69E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 Gene3D G3DSA:3.30.470.20 185 373 4.3E-39 T 28-03-2018 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 Gene3D G3DSA:3.40.50.20 9 94 1.8E-25 T 28-03-2018 CPF12_RS08675 2efe72f0cebfae14002692c2755ef262 373 Pfam PF02222 ATP-grasp domain 115 284 8.0E-53 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 Gene3D G3DSA:2.60.40.1180 387 542 1.6E-18 T 28-03-2018 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 SUPERFAMILY SSF88713 4 271 2.3E-56 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 Pfam PF09261 Alpha mannosidase middle domain 299 370 5.7E-8 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 SUPERFAMILY SSF74650 391 606 4.39E-64 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 SUPERFAMILY SSF74650 641 895 4.39E-64 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 5 270 2.1E-25 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 Gene3D G3DSA:1.20.1270.50 295 386 4.2E-21 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 SMART SM00872 297 370 4.8E-19 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 Gene3D G3DSA:3.20.110.10 1 218 1.4E-42 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 SUPERFAMILY SSF88688 298 394 6.21E-15 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CPF12_RS00325 94ad4b1b6533bd80e156926354ff01d1 901 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 403 889 1.4E-27 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CPF12_RS11850 1a339d359c9b714548e67fd7678a4bb7 243 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 227 3.3E-34 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CPF12_RS11850 1a339d359c9b714548e67fd7678a4bb7 243 Gene3D G3DSA:3.20.20.190 1 238 3.2E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS11850 1a339d359c9b714548e67fd7678a4bb7 243 SUPERFAMILY SSF51695 2 232 9.16E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS03635 cdd8bf318f690299722f448a6a8fd27f 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 260 1.8E-56 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS03635 cdd8bf318f690299722f448a6a8fd27f 268 Gene3D G3DSA:3.40.50.1000 1 268 1.4E-37 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03635 cdd8bf318f690299722f448a6a8fd27f 268 SUPERFAMILY SSF56784 1 266 3.0E-68 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03635 cdd8bf318f690299722f448a6a8fd27f 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 260 1.4E-58 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03635 cdd8bf318f690299722f448a6a8fd27f 268 ProSitePatterns PS01229 Hypothetical cof family signature 2. 215 237 - T 28-03-2018 CPF12_RS03635 cdd8bf318f690299722f448a6a8fd27f 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 234 2.9E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 Gene3D G3DSA:3.20.20.150 1 297 5.1E-53 T 28-03-2018 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 SUPERFAMILY SSF51658 2 291 3.87E-98 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 Pfam PF01261 Xylose isomerase-like TIM barrel 22 237 9.5E-35 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 41.521 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 SMART SM00518 3 285 3.1E-121 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 2.2E-94 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CPF12_RS10390 d46ba258604e50e751216e866deb0678 297 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 10 442 3.2E-161 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 Pfam PF04715 Anthranilate synthase component I, N terminal region 11 143 2.6E-27 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 PRINTS PR00095 Anthranilate synthase component I signature 282 295 1.4E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 PRINTS PR00095 Anthranilate synthase component I signature 391 405 1.4E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 PRINTS PR00095 Anthranilate synthase component I signature 376 390 1.4E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 PRINTS PR00095 Anthranilate synthase component I signature 296 309 1.4E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 SUPERFAMILY SSF56322 4 441 8.63E-141 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 Gene3D G3DSA:3.60.120.10 1 444 3.0E-151 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CPF12_RS01025 e609a18076f26e2a2b4f5301ee1e3c7e 449 Pfam PF00425 chorismate binding enzyme 181 434 3.1E-93 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 Gene3D G3DSA:3.40.50.1980 24 208 4.2E-59 T 28-03-2018 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 Pfam PF01297 Zinc-uptake complex component A periplasmic 38 326 4.0E-83 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 SUPERFAMILY SSF53807 34 328 8.34E-86 T 28-03-2018 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00691 Adhesin B signature 60 78 4.1E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00691 Adhesin B signature 35 56 4.1E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00691 Adhesin B signature 79 98 4.1E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00691 Adhesin B signature 307 325 4.1E-11 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 Gene3D G3DSA:3.40.50.1980 209 329 3.5E-39 T 28-03-2018 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00690 Adhesin family signature 35 53 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00690 Adhesin family signature 66 79 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS05095 ddb9bc97434ecb73c14ea2f920847d58 329 PRINTS PR00690 Adhesin family signature 79 96 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 SUPERFAMILY SSF54211 223 394 1.16E-50 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 176 1.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 SUPERFAMILY SSF55874 7 213 3.14E-65 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Pfam PF00204 DNA gyrase B 223 393 4.2E-56 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 222 244 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 363 377 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 313 329 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 197 210 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 377 397 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 8 18 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 475 484 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 594 606 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 182 197 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR01159 DNA gyrase subunit B signature 610 626 6.3E-60 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Gene3D G3DSA:3.30.565.10 20 222 5.0E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 SUPERFAMILY SSF56719 399 649 8.89E-85 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Gene3D G3DSA:3.40.50.670 405 637 1.3E-91 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 6 639 48.058 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 570 630 2.1E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Pfam PF01751 Toprim domain 424 533 3.4E-18 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 SMART SM00387 33 177 1.1E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 6 642 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 491 507 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 114 128 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 37 52 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 529 541 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 72 85 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 269 282 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 573 589 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 509 526 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 PRINTS PR00418 DNA topoisomerase II family signature 425 439 5.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 Gene3D G3DSA:3.30.230.10 223 395 1.9E-54 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS11840 00dd84ed4973976a863cfeda1aa5313c 659 SMART SM00433 37 634 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 SUPERFAMILY SSF56059 140 360 1.77E-56 T 28-03-2018 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 SUPERFAMILY SSF52440 1 139 1.53E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 Gene3D G3DSA:3.30.470.20 215 364 1.1E-38 T 28-03-2018 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 Pfam PF01820 D-ala D-ala ligase N-terminus 5 129 7.0E-29 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 297 325 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 Gene3D G3DSA:3.40.50.20 1 150 6.9E-39 T 28-03-2018 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 PIRSF PIRSF039102 1 363 1.9E-106 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 Pfam PF07478 D-ala D-ala ligase C-terminus 147 352 1.0E-71 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 Gene3D G3DSA:3.30.1490.20 155 214 2.3E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 354 1.1E-104 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS08310 e36fdc3a049eb2bead56a0db4ed30b46 369 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 355 39.733 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS10790 4f7e19cf1810f0a26d1edfca329ff374 186 SUPERFAMILY SSF55729 16 182 9.4E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS10790 4f7e19cf1810f0a26d1edfca329ff374 186 Gene3D G3DSA:3.40.630.30 6 186 3.9E-22 T 28-03-2018 CPF12_RS10790 4f7e19cf1810f0a26d1edfca329ff374 186 Pfam PF13302 Acetyltransferase (GNAT) domain 22 156 9.2E-26 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS00585 bde5160d79249048620c8a2fdeb1a975 466 TIGRFAM TIGR03236 dnd_assoc_1: DNA phosphorothioation-dependent restriction protein DptG 121 466 2.2E-35 T 28-03-2018 IPR017645 DNA phosphorothioation-dependent restriction protein DptG CPF12_RS00585 bde5160d79249048620c8a2fdeb1a975 466 Pfam PF01867 CRISPR associated protein Cas1 137 219 1.3E-5 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 SUPERFAMILY SSF52374 19 181 7.32E-28 T 28-03-2018 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 Pfam PF06574 FAD synthetase 15 168 6.0E-48 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 PIRSF PIRSF004491 4 316 1.4E-96 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 Gene3D G3DSA:3.40.50.620 5 181 2.3E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 Gene3D G3DSA:2.40.30.30 182 315 6.4E-36 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 310 1.3E-81 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 SUPERFAMILY SSF82114 176 310 2.62E-43 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 SMART SM00904 185 310 6.6E-55 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CPF12_RS12165 9b2bc40fc44b93b0d7dfc0c4d3f5878e 316 Pfam PF01687 Riboflavin kinase 186 308 8.6E-32 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 Gene3D G3DSA:3.20.20.80 2 472 1.5E-142 T 28-03-2018 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 SUPERFAMILY SSF51445 1 472 7.97E-156 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 Pfam PF00232 Glycosyl hydrolase family 1 2 471 4.6E-130 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 5.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 5.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 5.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 5.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04340 c418c287c79c43b7ad53ba9881ec4d55 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 5.0E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS10490 331683c72708bd92a6b325005a7d0caa 333 Gene3D G3DSA:1.20.5.510 307 331 7.5E-4 T 28-03-2018 CPF12_RS10490 331683c72708bd92a6b325005a7d0caa 333 Gene3D G3DSA:2.60.40.1710 37 158 1.1E-7 T 28-03-2018 CPF12_RS10490 331683c72708bd92a6b325005a7d0caa 333 Pfam PF06030 Bacterial protein of unknown function (DUF916) 28 147 4.5E-40 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CPF12_RS10490 331683c72708bd92a6b325005a7d0caa 333 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 158 294 1.0E-46 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CPF12_RS10490 331683c72708bd92a6b325005a7d0caa 333 Gene3D G3DSA:2.60.40.10 184 284 0.024 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 SUPERFAMILY SSF50104 126 273 1.38E-58 T 28-03-2018 IPR008991 Translation protein SH3-like domain CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 SMART SM01382 124 254 2.0E-93 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 276 48.755 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 277 7.2E-138 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 5.6E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 252 5.2E-57 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 Gene3D G3DSA:2.40.50.140 1 113 5.7E-49 T 28-03-2018 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 PIRSF PIRSF002158 3 277 1.2E-99 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 SMART SM01383 42 118 6.4E-46 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 Gene3D G3DSA:2.30.30.30 119 196 1.6E-32 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 Gene3D G3DSA:4.10.950.10 198 276 4.4E-34 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CPF12_RS06075 5e8e9bead1d99e04d3e2e8e34e2fc1ac 277 SUPERFAMILY SSF50249 3 125 8.23E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 8 650 0.0 T 28-03-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 279 333 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 SUPERFAMILY SSF81442 47 558 1.23E-170 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 277 298 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 368 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 382 400 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 460 481 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 226 245 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 119 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 338 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 410 429 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 49 74 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 123 147 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 197 215 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 165 177 8.4E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 Gene3D G3DSA:1.20.210.10 45 560 1.7E-184 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 58 504 6.9E-140 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05545 6a07c70c82acd3bf93553857a1e6bb9d 663 Gene3D G3DSA:1.10.287.70 574 641 2.2E-14 T 28-03-2018 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 SUPERFAMILY SSF63520 844 939 2.09E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 SMART SM00382 136 288 2.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Gene3D G3DSA:3.40.50.510 565 696 8.1E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Gene3D G3DSA:1.10.1790.10 441 564 3.4E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 SUPERFAMILY SSF63520 466 573 1.07E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Pfam PF00158 Sigma-54 interaction domain 113 279 5.3E-48 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Gene3D G3DSA:3.40.50.300 91 330 2.4E-20 T 28-03-2018 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Gene3D G3DSA:1.10.1790.10 842 943 3.2E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Pfam PF03610 PTS system fructose IIA component 580 687 1.6E-14 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Gene3D G3DSA:3.40.50.2300 720 814 6.3E-7 T 28-03-2018 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 SUPERFAMILY SSF52540 112 349 2.59E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Gene3D G3DSA:1.10.10.10 1 71 1.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 SUPERFAMILY SSF53062 578 696 2.88E-19 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CPF12_RS04000 e86d46c679566934420ad3df92f95c91 943 Pfam PF00874 PRD domain 483 568 7.9E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 Gene3D G3DSA:3.40.50.920 168 308 2.6E-30 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 Gene3D G3DSA:3.40.50.970 3 167 7.8E-38 T 28-03-2018 CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 SUPERFAMILY SSF52518 4 171 4.28E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 SMART SM00861 4 170 1.4E-33 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 Pfam PF02780 Transketolase, C-terminal domain 183 298 1.6E-21 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 Pfam PF02779 Transketolase, pyrimidine binding domain 4 165 1.5E-25 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS10745 3085750d468d1a9994fd02a1059a32ef 308 SUPERFAMILY SSF52922 183 307 2.49E-26 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 17 756 6.9E-248 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Pfam PF14490 Helix-hairpin-helix containing domain 158 249 1.4E-27 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Pfam PF13604 AAA domain 346 553 3.7E-51 T 28-03-2018 CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 SMART SM00382 359 520 6.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Gene3D G3DSA:3.40.50.300 528 743 4.0E-29 T 28-03-2018 CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Gene3D G3DSA:1.10.150.280 102 161 2.3E-4 T 28-03-2018 CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 SUPERFAMILY SSF52540 339 735 2.49E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 766 28.945 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Pfam PF13538 UvrD-like helicase C-terminal domain 682 730 7.0E-16 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CPF12_RS09630 752fd1edd980b0d74f5559b7204ac8fa 792 Gene3D G3DSA:3.40.50.300 301 527 8.6E-34 T 28-03-2018 CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 232 2.9E-22 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 134 226 1.2E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 SUPERFAMILY SSF56784 96 260 9.19E-39 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 SUPERFAMILY SSF56784 3 64 9.19E-39 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 111 231 1.5E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 Gene3D G3DSA:3.40.50.1000 1 121 0.0089 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07480 b7ebe374949a6b2baf46e858bc7ff6d8 262 Gene3D G3DSA:3.40.50.1000 122 262 7.9E-28 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 SUPERFAMILY SSF55315 4 76 5.53E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 SUPERFAMILY SSF75217 67 243 3.4E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 1.8E-21 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 Pfam PF00588 SpoU rRNA Methylase family 96 235 3.1E-38 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 Gene3D G3DSA:3.30.1330.30 1 74 5.2E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 242 8.6E-83 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 Gene3D G3DSA:3.40.1280.10 75 246 2.6E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CPF12_RS05965 cbfb6cc0eae65507f9f0da9a02cf0b04 247 SMART SM00967 5 79 1.3E-20 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 Gene3D G3DSA:2.40.50.140 295 349 3.8E-6 T 28-03-2018 CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 SUPERFAMILY SSF52540 4 244 2.87E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 Gene3D G3DSA:3.40.50.300 1 238 6.0E-73 T 28-03-2018 CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 SUPERFAMILY SSF50331 238 365 1.77E-24 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 SMART SM00382 30 213 5.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 Gene3D G3DSA:2.40.50.100 241 294 4.1E-13 T 28-03-2018 CPF12_RS02485 e39e3c8614926fbec403d784cebee4cb 367 Pfam PF00005 ABC transporter 22 163 9.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00330 964506bef6dd75110cb235d608b848f3 286 SUPERFAMILY SSF53067 1 284 9.72E-51 T 28-03-2018 CPF12_RS00330 964506bef6dd75110cb235d608b848f3 286 ProSitePatterns PS01125 ROK family signature. 129 154 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS00330 964506bef6dd75110cb235d608b848f3 286 Gene3D G3DSA:3.30.420.40 115 286 3.7E-42 T 28-03-2018 CPF12_RS00330 964506bef6dd75110cb235d608b848f3 286 Pfam PF00480 ROK family 4 283 1.6E-76 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS00330 964506bef6dd75110cb235d608b848f3 286 Gene3D G3DSA:3.30.420.40 2 114 2.4E-19 T 28-03-2018 CPF12_RS05515 d113eb9a4284ae0ac690915fd3af1a0e 147 Gene3D G3DSA:1.10.260.40 1 125 5.2E-22 T 28-03-2018 CPF12_RS05515 d113eb9a4284ae0ac690915fd3af1a0e 147 SUPERFAMILY SSF47413 1 67 4.02E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05515 d113eb9a4284ae0ac690915fd3af1a0e 147 Pfam PF01381 Helix-turn-helix 8 62 4.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05515 d113eb9a4284ae0ac690915fd3af1a0e 147 SMART SM00530 7 62 1.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS11495 0c3038d91f230d6bd461f5e64dd6ed74 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.804 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS11495 0c3038d91f230d6bd461f5e64dd6ed74 62 Pfam PF00830 Ribosomal L28 family 3 58 7.5E-20 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11495 0c3038d91f230d6bd461f5e64dd6ed74 62 Gene3D G3DSA:2.30.170.40 2 62 7.8E-20 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11495 0c3038d91f230d6bd461f5e64dd6ed74 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 1.8E-21 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS11495 0c3038d91f230d6bd461f5e64dd6ed74 62 SUPERFAMILY SSF143800 1 61 4.51E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05180 5a51c96e2f58ae1a8807c6501cc1cc59 310 Gene3D G3DSA:3.10.180.10 144 307 5.2E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS05180 5a51c96e2f58ae1a8807c6501cc1cc59 310 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 262 7.5E-21 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS05180 5a51c96e2f58ae1a8807c6501cc1cc59 310 SUPERFAMILY SSF54593 1 278 2.5E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS05180 5a51c96e2f58ae1a8807c6501cc1cc59 310 Gene3D G3DSA:3.10.180.10 1 132 1.3E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS05660 404916193068412f60f83d73f3a38e94 220 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 30.504 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CPF12_RS05660 404916193068412f60f83d73f3a38e94 220 Pfam PF02223 Thymidylate kinase 9 201 5.9E-56 T 28-03-2018 CPF12_RS05660 404916193068412f60f83d73f3a38e94 220 SUPERFAMILY SSF52540 1 212 6.23E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05660 404916193068412f60f83d73f3a38e94 220 Gene3D G3DSA:3.40.50.300 1 212 2.0E-52 T 28-03-2018 CPF12_RS05660 404916193068412f60f83d73f3a38e94 220 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CPF12_RS05660 404916193068412f60f83d73f3a38e94 220 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 201 1.2E-60 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 460 490 6.7E-5 T 28-03-2018 CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 Pfam PF16555 Gram-positive pilin subunit D1, N-terminal 28 189 8.1E-19 T 28-03-2018 IPR032364 Gram-positive pilin subunit D1, N-terminal CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 Gene3D G3DSA:2.60.40.810 333 457 6.8E-13 T 28-03-2018 CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 Gene3D G3DSA:2.60.40.810 23 204 4.7E-7 T 28-03-2018 CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 SUPERFAMILY SSF49401 218 333 7.45E-8 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 Gene3D G3DSA:2.60.40.740 205 332 7.2E-17 T 28-03-2018 CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 220 329 1.1E-9 T 28-03-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 191 325 2.4E-13 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CPF12_RS03535 ad683d0a051d3b923568651d60c9becf 495 Pfam PF00746 LPXTG cell wall anchor motif 455 490 1.8E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS07880 3a528c4ccc25a402103cb67d1a621a02 560 SMART SM00642 13 418 9.5E-137 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS07880 3a528c4ccc25a402103cb67d1a621a02 560 SUPERFAMILY SSF51445 4 476 8.75E-147 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07880 3a528c4ccc25a402103cb67d1a621a02 560 Gene3D G3DSA:3.20.20.80 2 479 2.9E-125 T 28-03-2018 CPF12_RS07880 3a528c4ccc25a402103cb67d1a621a02 560 SUPERFAMILY SSF51011 479 552 4.63E-10 T 28-03-2018 CPF12_RS07880 3a528c4ccc25a402103cb67d1a621a02 560 Gene3D G3DSA:2.60.40.1180 480 555 8.8E-12 T 28-03-2018 CPF12_RS07880 3a528c4ccc25a402103cb67d1a621a02 560 Pfam PF00128 Alpha amylase, catalytic domain 28 375 7.6E-119 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS09725 29e3b0a9c8b44dbabdbbc4f029d0e4cd 595 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 9 593 1.7E-190 T 28-03-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 CPF12_RS09725 29e3b0a9c8b44dbabdbbc4f029d0e4cd 595 Pfam PF01432 Peptidase family M3 335 580 2.4E-17 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CPF12_RS09725 29e3b0a9c8b44dbabdbbc4f029d0e4cd 595 Pfam PF08439 Oligopeptidase F 116 180 8.4E-15 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CPF12_RS09725 29e3b0a9c8b44dbabdbbc4f029d0e4cd 595 SUPERFAMILY SSF55486 9 579 6.83E-90 T 28-03-2018 CPF12_RS09725 29e3b0a9c8b44dbabdbbc4f029d0e4cd 595 Gene3D G3DSA:1.10.1370.10 82 576 8.3E-10 T 28-03-2018 CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 Pfam PF02033 Ribosome-binding factor A 5 108 4.4E-33 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 23.765 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 113 7.0E-36 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 Gene3D G3DSA:3.30.300.20 3 115 2.5E-36 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 SUPERFAMILY SSF89919 1 111 1.19E-36 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CPF12_RS12175 faa0f76a7e94236a77310ac730d4cbe7 115 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 92 1.0E-31 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CPF12_RS12100 d9629fc2066066f1787c3aa43c284cab 242 Pfam PF00005 ABC transporter 17 165 7.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS12100 d9629fc2066066f1787c3aa43c284cab 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS12100 d9629fc2066066f1787c3aa43c284cab 242 SMART SM00382 26 213 1.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12100 d9629fc2066066f1787c3aa43c284cab 242 SUPERFAMILY SSF52540 1 235 9.04E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12100 d9629fc2066066f1787c3aa43c284cab 242 PIRSF PIRSF039085 1 241 4.8E-110 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CPF12_RS12100 d9629fc2066066f1787c3aa43c284cab 242 Gene3D G3DSA:3.40.50.300 1 241 1.1E-72 T 28-03-2018 CPF12_RS09355 ce8338477de48be7d3e25c7b8c5bf411 131 Gene3D G3DSA:3.40.140.10 1 131 4.5E-53 T 28-03-2018 CPF12_RS09355 ce8338477de48be7d3e25c7b8c5bf411 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 4.3E-48 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CPF12_RS09355 ce8338477de48be7d3e25c7b8c5bf411 131 SUPERFAMILY SSF53927 5 130 6.86E-50 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CPF12_RS09355 ce8338477de48be7d3e25c7b8c5bf411 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 97 6.0E-17 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CPF12_RS09355 ce8338477de48be7d3e25c7b8c5bf411 131 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 126 28.258 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 SUPERFAMILY SSF81330 10 108 1.31E-33 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 122 5.2E-41 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 124 2.5E-47 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 6.8E-13 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 6.8E-13 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS00840 87593c2523db7970cc5433777a7949eb 127 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 6.8E-13 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 120 4.3E-32 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 Gene3D G3DSA:3.30.360.10 141 324 7.2E-67 T 28-03-2018 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 237 251 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 Gene3D G3DSA:3.40.50.720 1 140 1.2E-33 T 28-03-2018 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 SUPERFAMILY SSF51735 5 157 3.27E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 342 1.7E-140 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 341 36.368 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 SUPERFAMILY SSF55347 129 328 8.33E-68 T 28-03-2018 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 327 2.0E-52 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 PIRSF PIRSF000148 4 346 7.1E-125 T 28-03-2018 CPF12_RS12130 56ead7ca355725a93afe45b2d12ee743 346 SMART SM00859 6 121 4.1E-41 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CPF12_RS08635 51e632706b7a3b2d7b410df124dee66a 167 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 80 92 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS08635 51e632706b7a3b2d7b410df124dee66a 167 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 140 1.4E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS08635 51e632706b7a3b2d7b410df124dee66a 167 Gene3D G3DSA:2.70.70.10 5 166 1.9E-55 T 28-03-2018 CPF12_RS08635 51e632706b7a3b2d7b410df124dee66a 167 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 17 138 3.0E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS08635 51e632706b7a3b2d7b410df124dee66a 167 SUPERFAMILY SSF51261 7 162 1.5E-52 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS02555 8a7cb3e6e5207745066d8677bc1bba5a 348 SUPERFAMILY SSF53187 180 342 1.35E-51 T 28-03-2018 CPF12_RS02555 8a7cb3e6e5207745066d8677bc1bba5a 348 SUPERFAMILY SSF53187 7 86 1.35E-51 T 28-03-2018 CPF12_RS02555 8a7cb3e6e5207745066d8677bc1bba5a 348 PIRSF PIRSF001123 5 338 5.8E-37 T 28-03-2018 IPR008007 Peptidase M42 CPF12_RS02555 8a7cb3e6e5207745066d8677bc1bba5a 348 Gene3D G3DSA:3.40.630.10 1 343 3.7E-42 T 28-03-2018 CPF12_RS02555 8a7cb3e6e5207745066d8677bc1bba5a 348 Pfam PF05343 M42 glutamyl aminopeptidase 49 336 2.8E-82 T 28-03-2018 IPR008007 Peptidase M42 CPF12_RS02555 8a7cb3e6e5207745066d8677bc1bba5a 348 SUPERFAMILY SSF101821 74 185 5.04E-27 T 28-03-2018 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 SUPERFAMILY SSF46785 1 83 1.58E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 SUPERFAMILY SSF53850 90 291 2.78E-33 T 28-03-2018 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 Gene3D G3DSA:3.40.190.10 176 263 1.9E-15 T 28-03-2018 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 Gene3D G3DSA:1.10.10.10 1 90 8.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 Gene3D G3DSA:3.40.190.10 91 175 5.3E-16 T 28-03-2018 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 57 4.7E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS00720 9a3d03c51a8f1d8503174c4b99135b72 292 Pfam PF03466 LysR substrate binding domain 88 288 1.1E-34 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS04235 0c9360e62b1c0a70468455870d762a9a 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 120 9.7E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS04235 0c9360e62b1c0a70468455870d762a9a 124 Gene3D G3DSA:3.10.180.10 1 123 2.0E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS04235 0c9360e62b1c0a70468455870d762a9a 124 SUPERFAMILY SSF54593 1 121 4.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03265 ddaa8b8426f05eb73c538cd6b8552b2c 162 Pfam PF09335 SNARE associated Golgi protein 29 155 3.1E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF04565 RNA polymerase Rpb2, domain 3 467 535 5.4E-31 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF04561 RNA polymerase Rpb2, domain 2 369 408 1.2E-6 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 6.8E-29 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF04560 RNA polymerase Rpb2, domain 7 1069 1143 3.4E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 SUPERFAMILY SSF64484 365 1156 0.0 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 SUPERFAMILY SSF64484 13 288 0.0 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF10385 RNA polymerase beta subunit external 1 domain 545 612 9.4E-25 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:2.40.50.100 670 749 2.5E-23 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:2.40.270.10 848 1053 4.2E-76 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1145 12.537 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 894 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 ProSitePatterns PS01166 RNA polymerases beta chain signature. 920 932 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF00562 RNA polymerase Rpb2, domain 6 674 1067 1.3E-161 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:3.90.1100.10 20 242 6.7E-57 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:3.90.1100.10 603 669 1.6E-12 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:3.90.1100.10 300 602 7.2E-83 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:3.90.1800.10 1070 1116 1.6E-11 T 28-03-2018 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Pfam PF04563 RNA polymerase beta subunit 29 452 2.7E-28 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06020 ba7f544c313a3c25b9a9ba658e057b8e 1186 Gene3D G3DSA:2.40.270.10 750 847 8.4E-12 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 4.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 4.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 SMART SM00345 14 73 2.6E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 Gene3D G3DSA:1.10.10.10 1 72 1.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.2E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 Gene3D G3DSA:3.40.1410.10 73 240 5.8E-42 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 Pfam PF07702 UTRA domain 95 233 2.8E-36 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 SMART SM00866 94 233 5.2E-37 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 SUPERFAMILY SSF64288 61 238 3.77E-47 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS08290 4af09d34acfae58fe1da2d67fdd10676 241 SUPERFAMILY SSF46785 1 77 1.28E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12335 0a45063c65da0f23e062d7ae037af182 241 Pfam PF00696 Amino acid kinase family 7 217 1.5E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS12335 0a45063c65da0f23e062d7ae037af182 241 Gene3D G3DSA:3.40.1160.10 1 239 1.2E-45 T 28-03-2018 CPF12_RS12335 0a45063c65da0f23e062d7ae037af182 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 1.5E-100 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CPF12_RS12335 0a45063c65da0f23e062d7ae037af182 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 44.604 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CPF12_RS12335 0a45063c65da0f23e062d7ae037af182 241 SUPERFAMILY SSF53633 4 238 1.23E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS12335 0a45063c65da0f23e062d7ae037af182 241 PIRSF PIRSF005650 1 241 1.5E-97 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CPF12_RS12060 01a95b3354974f754520c4850235a506 331 SUPERFAMILY SSF46689 4 44 2.24E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS12060 01a95b3354974f754520c4850235a506 331 SUPERFAMILY SSF53098 174 322 1.9E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS12060 01a95b3354974f754520c4850235a506 331 Gene3D G3DSA:3.30.420.10 166 328 5.5E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS12060 01a95b3354974f754520c4850235a506 331 Pfam PF00665 Integrase core domain 175 283 1.0E-11 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS12060 01a95b3354974f754520c4850235a506 331 Gene3D G3DSA:1.10.10.60 3 47 1.2E-15 T 28-03-2018 CPF12_RS12060 01a95b3354974f754520c4850235a506 331 Pfam PF13936 Helix-turn-helix domain 2 45 1.0E-16 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 438 590 1.9E-40 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 SUPERFAMILY SSF52518 1 209 1.33E-28 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 SUPERFAMILY SSF52467 211 373 6.14E-34 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 219 351 2.3E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 Gene3D G3DSA:3.40.50.970 1 210 6.5E-42 T 28-03-2018 CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 Gene3D G3DSA:3.40.50.970 390 607 1.2E-36 T 28-03-2018 CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 Gene3D G3DSA:3.40.50.1220 211 387 3.8E-32 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 SUPERFAMILY SSF52518 417 622 1.22E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 193 9.5E-30 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS10980 1bd7b85ac9345913bc28b9614bd081e7 635 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 5 633 4.9E-256 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 SUPERFAMILY SSF69189 305 398 3.53E-12 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 SMART SM00936 310 417 7.7E-7 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 7.9E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 121 138 7.9E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 7.9E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 Gene3D G3DSA:2.60.410.10 314 417 2.7E-10 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 322 417 3.0E-8 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 SUPERFAMILY SSF56601 3 313 3.81E-64 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 Gene3D G3DSA:3.40.710.10 25 313 1.3E-43 T 28-03-2018 CPF12_RS05575 e9c400c058050d95c1347575e3648ce2 448 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 285 1.1E-70 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 SUPERFAMILY SSF52172 3 125 3.27E-42 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 Pfam PF00072 Response regulator receiver domain 4 114 1.5E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 SUPERFAMILY SSF46894 132 231 4.25E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 SMART SM00448 2 113 2.5E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 Gene3D G3DSA:1.10.10.10 130 235 2.5E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 7.1E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 SMART SM00862 155 231 5.5E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS06690 eae167a11b1767e3b2c24a966e570e52 235 Gene3D G3DSA:3.40.50.2300 2 129 4.9E-37 T 28-03-2018 CPF12_RS05150 85b1b602c8765cc22f8c7ba78753a349 258 Gene3D G3DSA:1.10.10.10 1 112 1.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05150 85b1b602c8765cc22f8c7ba78753a349 258 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 71 4.2E-20 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CPF12_RS05150 85b1b602c8765cc22f8c7ba78753a349 258 SUPERFAMILY SSF53697 91 252 8.34E-30 T 28-03-2018 CPF12_RS05150 85b1b602c8765cc22f8c7ba78753a349 258 Pfam PF01380 SIS domain 116 218 2.0E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS05150 85b1b602c8765cc22f8c7ba78753a349 258 Gene3D G3DSA:3.40.50.10490 113 251 1.3E-21 T 28-03-2018 CPF12_RS05150 85b1b602c8765cc22f8c7ba78753a349 258 SUPERFAMILY SSF46689 3 74 3.76E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS05155 146396383fe8b1471b76113dde6ffc61 563 Pfam PF03109 ABC1 family 118 234 8.1E-31 T 28-03-2018 IPR004147 UbiB domain CPF12_RS05155 146396383fe8b1471b76113dde6ffc61 563 Gene3D G3DSA:3.30.200.20 107 248 3.5E-16 T 28-03-2018 CPF12_RS05155 146396383fe8b1471b76113dde6ffc61 563 SUPERFAMILY SSF56112 100 163 1.33E-18 T 28-03-2018 IPR011009 Protein kinase-like domain CPF12_RS05155 146396383fe8b1471b76113dde6ffc61 563 SUPERFAMILY SSF56112 198 315 1.33E-18 T 28-03-2018 IPR011009 Protein kinase-like domain CPF12_RS05155 146396383fe8b1471b76113dde6ffc61 563 Gene3D G3DSA:1.10.510.10 257 377 2.9E-4 T 28-03-2018 CPF12_RS09685 6cb2220a1d85cb5e29c75813d2dee6ff 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 1.9E-46 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CPF12_RS09685 6cb2220a1d85cb5e29c75813d2dee6ff 138 SMART SM00732 1 103 5.2E-40 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CPF12_RS09685 6cb2220a1d85cb5e29c75813d2dee6ff 138 SUPERFAMILY SSF53098 1 137 3.19E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS09685 6cb2220a1d85cb5e29c75813d2dee6ff 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 26.536 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CPF12_RS09685 6cb2220a1d85cb5e29c75813d2dee6ff 138 Gene3D G3DSA:3.30.420.140 1 138 6.3E-46 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CPF12_RS09685 6cb2220a1d85cb5e29c75813d2dee6ff 138 Pfam PF03652 Holliday junction resolvase 1 136 8.8E-44 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 Pfam PF00874 PRD domain 77 165 1.8E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 Pfam PF00874 PRD domain 184 275 7.4E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 SMART SM01061 1 56 1.6E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 SUPERFAMILY SSF50151 1 53 4.58E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 SUPERFAMILY SSF63520 64 167 9.94E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 Pfam PF03123 CAT RNA binding domain 1 54 4.8E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 Gene3D G3DSA:1.10.1790.10 167 282 1.9E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 Gene3D G3DSA:2.30.24.10 1 65 1.0E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 SUPERFAMILY SSF63520 174 278 1.57E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04360 345a9d85542dd5503207793faaed9952 284 Gene3D G3DSA:1.10.1790.10 66 166 2.4E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04680 1047fba19eb9b2176238ab384ce3598e 270 Pfam PF13560 Helix-turn-helix domain 34 85 2.0E-13 T 28-03-2018 CPF12_RS04680 1047fba19eb9b2176238ab384ce3598e 270 SUPERFAMILY SSF47413 33 85 6.52E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS04680 1047fba19eb9b2176238ab384ce3598e 270 Gene3D G3DSA:1.10.260.40 1 103 5.3E-15 T 28-03-2018 CPF12_RS04680 1047fba19eb9b2176238ab384ce3598e 270 Gene3D G3DSA:3.30.450.20 107 227 8.3E-4 T 28-03-2018 CPF12_RS04680 1047fba19eb9b2176238ab384ce3598e 270 SMART SM00530 13 86 9.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 Pfam PF07690 Major Facilitator Superfamily 17 346 1.6E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 Gene3D G3DSA:1.20.1250.20 201 381 1.1E-12 T 28-03-2018 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 SUPERFAMILY SSF103473 8 377 4.58E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 PRINTS PR01988 Putative bacilysin exporter bacE signature 352 375 5.8E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 PRINTS PR01988 Putative bacilysin exporter bacE signature 245 262 5.8E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 PRINTS PR01988 Putative bacilysin exporter bacE signature 100 118 5.8E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 PRINTS PR01988 Putative bacilysin exporter bacE signature 209 231 5.8E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CPF12_RS03120 89fdee409f4908b93276e9522db0b04e 387 Gene3D G3DSA:1.20.1250.20 2 200 2.2E-20 T 28-03-2018 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 Gene3D G3DSA:1.20.5.320 437 470 6.3E-21 T 28-03-2018 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PIRSF PIRSF000109 1 471 1.4E-240 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 469 2.8E-225 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 468 2.7E-135 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 SMART SM01350 179 469 4.3E-227 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 173 2.8E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 358 380 2.3E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 2.3E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 2.3E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 2.3E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 2.3E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 250 277 2.3E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 Gene3D G3DSA:3.40.50.720 1 180 3.9E-36 T 28-03-2018 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 254 266 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 SUPERFAMILY SSF48179 177 470 1.16E-132 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 Gene3D G3DSA:1.10.1040.10 181 436 5.1E-114 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CPF12_RS09260 1d2900a2707702768450444a700a7638 471 SUPERFAMILY SSF51735 4 173 4.44E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08020 7a7abf0676d2ec918c57c82ee2862d60 75 Gene3D G3DSA:1.10.260.40 1 75 5.2E-10 T 28-03-2018 CPF12_RS08020 7a7abf0676d2ec918c57c82ee2862d60 75 SMART SM00530 5 61 9.9E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS08020 7a7abf0676d2ec918c57c82ee2862d60 75 SUPERFAMILY SSF47413 13 65 3.38E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS08020 7a7abf0676d2ec918c57c82ee2862d60 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 1.2E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS03285 456dc06b1fde7be4315ae344309606bc 331 SUPERFAMILY SSF51735 2 139 1.25E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03285 456dc06b1fde7be4315ae344309606bc 331 Gene3D G3DSA:3.40.50.720 1 145 1.5E-25 T 28-03-2018 CPF12_RS03285 456dc06b1fde7be4315ae344309606bc 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 4.5E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CPF12_RS03285 456dc06b1fde7be4315ae344309606bc 331 Gene3D G3DSA:3.30.360.10 146 331 1.2E-14 T 28-03-2018 CPF12_RS03285 456dc06b1fde7be4315ae344309606bc 331 SUPERFAMILY SSF55347 132 266 1.26E-11 T 28-03-2018 CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 Gene3D G3DSA:3.40.50.300 4 211 9.8E-43 T 28-03-2018 CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 Gene3D G3DSA:3.40.50.300 212 362 3.9E-41 T 28-03-2018 CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 SMART SM00487 18 213 1.5E-35 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 SMART SM00490 248 329 1.3E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 Pfam PF00271 Helicase conserved C-terminal domain 221 329 3.2E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 SUPERFAMILY SSF52540 66 350 3.67E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08995 4e77bac0db3cffd839caaeb4b0f98b9c 374 Pfam PF00270 DEAD/DEAH box helicase 23 184 9.8E-35 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 Gene3D G3DSA:1.20.1250.20 85 279 8.7E-4 T 28-03-2018 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 Pfam PF02378 Phosphotransferase system, EIIC 135 399 7.3E-13 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 484 610 2.9E-34 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 Gene3D G3DSA:3.40.930.10 478 627 1.2E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 119 454 1.4E-103 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 SUPERFAMILY SSF52794 2 102 1.24E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 483 625 5.2E-34 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 87 6.4E-34 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 SUPERFAMILY SSF55804 480 625 1.31E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 94 8.5E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS05140 e95e23483873cff38c2a7e84dc1e3d9e 628 Gene3D G3DSA:3.40.50.2300 2 84 8.9E-39 T 28-03-2018 CPF12_RS01175 67791f9426395be7c8838d1422032032 272 Pfam PF01844 HNH endonuclease 103 144 9.1E-6 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CPF12_RS01175 67791f9426395be7c8838d1422032032 272 Gene3D G3DSA:3.40.1800.10 96 154 1.6E-6 T 28-03-2018 CPF12_RS01175 67791f9426395be7c8838d1422032032 272 SUPERFAMILY SSF144020 102 165 6.28E-5 T 28-03-2018 IPR024064 FdhE-like CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 SUPERFAMILY SSF50447 448 529 2.87E-22 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Pfam PF00009 Elongation factor Tu GTP binding domain 279 436 2.2E-35 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 SUPERFAMILY SSF52156 554 682 5.1E-39 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Gene3D G3DSA:3.30.56.50 4 46 8.0E-11 T 28-03-2018 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Gene3D G3DSA:3.30.56.50 200 241 2.2E-10 T 28-03-2018 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Gene3D G3DSA:2.40.30.10 676 774 2.1E-29 T 28-03-2018 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Gene3D G3DSA:2.40.30.10 443 540 1.6E-12 T 28-03-2018 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 190 773 1.7E-258 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 278 434 1.8E-37 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Gene3D G3DSA:3.40.50.300 270 442 3.3E-40 T 28-03-2018 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 773 17.056 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 47 2.3E-13 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 198 248 1.3E-14 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Gene3D G3DSA:3.40.50.10050 573 654 9.8E-28 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 Pfam PF11987 Translation-initiation factor 2 560 665 1.3E-37 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 SUPERFAMILY SSF50447 676 773 1.46E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS12180 02c043acce03f9f75d438e58e7e6e1cf 777 SUPERFAMILY SSF52540 264 447 3.37E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04410 b6c0c5422c04e46f62795b0a18720ea2 564 SUPERFAMILY SSF55874 417 557 3.41E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04410 b6c0c5422c04e46f62795b0a18720ea2 564 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 455 557 5.6E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04410 b6c0c5422c04e46f62795b0a18720ea2 564 SMART SM00387 447 559 1.5E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04410 b6c0c5422c04e46f62795b0a18720ea2 564 Gene3D G3DSA:3.30.450.20 43 196 0.0019 T 28-03-2018 CPF12_RS04410 b6c0c5422c04e46f62795b0a18720ea2 564 Gene3D G3DSA:3.30.565.10 327 558 1.9E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04410 b6c0c5422c04e46f62795b0a18720ea2 564 Pfam PF06580 Histidine kinase 359 436 3.2E-22 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CPF12_RS07085 92b7dca4b554f2530e5ed371bb3dce9b 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 2.1E-17 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07085 92b7dca4b554f2530e5ed371bb3dce9b 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 2.1E-17 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07085 92b7dca4b554f2530e5ed371bb3dce9b 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 2.1E-17 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07085 92b7dca4b554f2530e5ed371bb3dce9b 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 2.1E-17 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07085 92b7dca4b554f2530e5ed371bb3dce9b 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 325 344 2.1E-17 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07085 92b7dca4b554f2530e5ed371bb3dce9b 496 Pfam PF00361 Proton-conducting membrane transporter 128 419 2.0E-44 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 425 3.3E-201 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 Gene3D G3DSA:3.40.640.10 7 291 2.2E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 425 8.0E-145 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 SUPERFAMILY SSF53383 8 425 2.93E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 Gene3D G3DSA:3.90.1150.10 293 429 1.5E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS09265 996547f412b12a46228c385ba4cd44c7 429 PIRSF PIRSF001434 1 428 1.1E-131 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Pfam PF00571 CBS domain 218 243 5.8E-5 T 28-03-2018 IPR000644 CBS domain CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Pfam PF00571 CBS domain 255 306 6.7E-7 T 28-03-2018 IPR000644 CBS domain CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Gene3D G3DSA:3.10.129.10 304 437 1.0E-17 T 28-03-2018 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Gene3D G3DSA:3.10.580.10 190 303 7.6E-26 T 28-03-2018 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Pfam PF03061 Thioesterase superfamily 353 420 7.5E-5 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 SUPERFAMILY SSF75138 72 185 1.7E-29 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 SMART SM00116 259 307 0.0024 T 28-03-2018 IPR000644 CBS domain CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 SMART SM00116 200 248 0.046 T 28-03-2018 IPR000644 CBS domain CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Pfam PF07085 DRTGG domain 76 178 1.6E-28 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 58 6.3E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Gene3D G3DSA:1.10.10.10 4 69 1.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 Gene3D G3DSA:3.40.1390.20 70 189 3.3E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 SUPERFAMILY SSF54631 182 307 3.54E-29 T 28-03-2018 CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 SUPERFAMILY SSF54637 340 422 2.3E-12 T 28-03-2018 IPR029069 HotDog domain CPF12_RS08410 572984bb7d2920f427f4b498bff95998 437 SUPERFAMILY SSF46785 14 64 4.09E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Gene3D G3DSA:1.10.150.20 4 50 9.9E-4 T 28-03-2018 CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 653 1.8E-237 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Pfam PF17191 RecG wedge domain 9 167 4.2E-16 T 28-03-2018 IPR033454 RecG, wedge domain CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Pfam PF00271 Helicase conserved C-terminal domain 467 578 6.4E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Gene3D G3DSA:2.40.50.140 51 142 2.0E-7 T 28-03-2018 CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Gene3D G3DSA:3.40.50.300 245 445 1.2E-36 T 28-03-2018 CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 SUPERFAMILY SSF52540 441 643 6.27E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Gene3D G3DSA:3.40.50.300 446 618 7.2E-31 T 28-03-2018 CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 Pfam PF00270 DEAD/DEAH box helicase 265 420 7.4E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 SUPERFAMILY SSF52540 178 441 2.58E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 SMART SM00490 493 578 7.3E-25 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 SUPERFAMILY SSF50249 7 172 3.94E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS11510 76935999aea9b10de72339e6eda2929f 686 SMART SM00487 258 448 3.5E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS10590 3c0621bbb6a3bcb65f91c9fa2b89aee0 346 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 119 339 1.7E-28 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CPF12_RS10590 3c0621bbb6a3bcb65f91c9fa2b89aee0 346 SUPERFAMILY SSF51695 113 343 1.1E-52 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS10590 3c0621bbb6a3bcb65f91c9fa2b89aee0 346 Gene3D G3DSA:3.20.20.190 99 345 2.2E-55 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS10590 3c0621bbb6a3bcb65f91c9fa2b89aee0 346 Pfam PF06114 IrrE N-terminal-like domain 2 52 2.0E-6 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Gene3D G3DSA:3.30.70.370 608 719 8.1E-35 T 28-03-2018 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SUPERFAMILY SSF56672 473 879 8.67E-154 T 28-03-2018 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Gene3D G3DSA:1.20.1060.10 494 607 2.9E-31 T 28-03-2018 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Gene3D G3DSA:3.30.420.10 313 493 2.0E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SMART SM00482 636 843 2.3E-113 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SMART SM00279 175 210 6.8E-19 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SMART SM00474 304 469 1.2E-9 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Gene3D G3DSA:3.40.50.1010 4 186 3.3E-63 T 28-03-2018 IPR029060 PIN domain-like CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SUPERFAMILY SSF53098 317 464 7.28E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SMART SM00475 4 264 4.3E-139 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 605 627 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 643 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 694 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 839 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 674 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 753 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 812 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 730 9.8E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Gene3D G3DSA:1.10.150.20 187 265 2.5E-29 T 28-03-2018 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Pfam PF00476 DNA polymerase family A 502 877 3.2E-155 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SUPERFAMILY SSF47807 173 286 6.43E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 SUPERFAMILY SSF88723 4 166 1.68E-48 T 28-03-2018 IPR029060 PIN domain-like CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 171 3.3E-50 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 266 3.6E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 TIGRFAM TIGR00593 pola: DNA polymerase I 6 879 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 ProSitePatterns PS00447 DNA polymerase family A signature. 705 724 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08475 ae64189e70931f6ece053a02eefa1d41 879 Gene3D G3DSA:3.30.70.370 720 879 1.7E-51 T 28-03-2018 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 1.0E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 SUPERFAMILY SSF55681 110 424 2.39E-98 T 28-03-2018 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 2.4E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 2.4E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 2.4E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 2.4E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 3 429 7.0E-161 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 1.7E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 Gene3D G3DSA:2.40.50.140 3 102 3.0E-19 T 28-03-2018 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 Gene3D G3DSA:3.30.930.10 103 430 1.9E-91 T 28-03-2018 CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 SUPERFAMILY SSF50249 9 102 1.24E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS10340 44622976579c17d47ff64976b5198f41 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 41.646 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 PRINTS PR00050 Cold shock protein signature 24 33 1.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 PRINTS PR00050 Cold shock protein signature 39 57 1.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 SMART SM00357 3 66 5.6E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 SUPERFAMILY SSF50249 1 65 3.64E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 PIRSF PIRSF002599 1 68 6.3E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 Gene3D G3DSA:2.40.50.140 1 66 6.2E-27 T 28-03-2018 CPF12_RS10535 ffb9eae380c4860cb027543958af4d90 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 8.7E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 SUPERFAMILY SSF64288 57 237 5.02E-38 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 69 8.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 SMART SM00866 94 230 1.9E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 4.3E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 4.3E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 Pfam PF07702 UTRA domain 98 230 2.8E-30 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 SMART SM00345 10 69 1.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 6 237 2.8E-88 T 28-03-2018 IPR012770 Trehalose operon transcriptional repressor CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 Gene3D G3DSA:1.10.10.10 2 70 9.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 SUPERFAMILY SSF46785 3 73 2.63E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06865 7de0214bb22e9185361609d272e6991b 239 Gene3D G3DSA:3.40.1410.10 73 239 1.2E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Gene3D G3DSA:1.10.150.20 241 314 5.8E-26 T 28-03-2018 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 SUPERFAMILY SSF56553 50 171 6.41E-45 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Gene3D G3DSA:3.30.1360.10 92 224 1.8E-25 T 28-03-2018 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Gene3D G3DSA:3.30.1360.10 1 85 1.5E-18 T 28-03-2018 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 3.1E-21 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 36.453 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 3.6E-29 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 5.0E-24 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 SMART SM00662 20 227 1.9E-99 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 SUPERFAMILY SSF47789 247 311 1.44E-23 T 28-03-2018 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 55 152 5.1E-26 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 312 1.0E-121 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 SUPERFAMILY SSF55257 146 230 6.15E-31 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06190 44d53a00c3f14d15b5822ba7ca6414e5 314 SUPERFAMILY SSF55257 5 54 6.15E-31 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 3.1E-79 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 SMART SM00363 92 156 5.2E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 Gene3D G3DSA:1.10.1050.10 1 97 1.0E-36 T 28-03-2018 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 SMART SM01390 3 91 3.9E-40 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 Gene3D G3DSA:3.10.290.10 98 140 1.5E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 8.1E-27 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 SUPERFAMILY SSF55174 2 200 1.28E-66 T 28-03-2018 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 34.898 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 Gene3D G3DSA:1.10.1050.10 141 200 2.3E-12 T 28-03-2018 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS08915 e19bea37e49bddc7410cc1935f01c739 200 Pfam PF01479 S4 domain 92 139 1.9E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS10825 9380cc4485470057ec6b297627bf5dd6 121 Pfam PF14189 Domain of unknown function (DUF4312) 9 91 1.8E-30 T 28-03-2018 IPR020037 Protein of unknown function DUF4312 CPF12_RS10825 9380cc4485470057ec6b297627bf5dd6 121 TIGRFAM TIGR03578 EF_0831: conserved hypothetical protein EF_0831/AHA_3912 5 99 1.2E-33 T 28-03-2018 IPR020037 Protein of unknown function DUF4312 CPF12_RS02415 cbbd03fb3a59a6613f2804077c226f09 118 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 60 104 5.7E-6 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS04600 166e9922e2c97673fd2c43357f37da2b 105 Gene3D G3DSA:1.10.287.1080 1 98 2.7E-10 T 28-03-2018 CPF12_RS04600 166e9922e2c97673fd2c43357f37da2b 105 SUPERFAMILY SSF101386 13 95 6.73E-7 T 28-03-2018 CPF12_RS04600 166e9922e2c97673fd2c43357f37da2b 105 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 18 92 1.5E-4 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Pfam PF13328 HD domain 31 180 2.0E-52 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Gene3D G3DSA:3.10.20.30 388 461 2.9E-23 T 28-03-2018 IPR012675 Beta-grasp domain CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Pfam PF13291 ACT domain 663 739 1.6E-18 T 28-03-2018 IPR002912 ACT domain CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 SMART SM00471 46 158 1.7E-8 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 SUPERFAMILY SSF81301 197 370 4.09E-66 T 28-03-2018 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 739 1.7E-250 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Gene3D G3DSA:3.30.460.10 193 330 1.5E-45 T 28-03-2018 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 1.5E-38 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 SUPERFAMILY SSF55021 665 741 1.03E-10 T 28-03-2018 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Gene3D G3DSA:3.30.70.260 662 742 1.1E-11 T 28-03-2018 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 SUPERFAMILY SSF81271 381 453 8.99E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 Pfam PF02824 TGS domain 394 453 6.0E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 SUPERFAMILY SSF109604 9 195 7.85E-75 T 28-03-2018 CPF12_RS01835 cd7eaaa23032857534728eb706625519 742 SMART SM00954 240 350 2.2E-67 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CPF12_RS00975 46247d5c4538b115d3a26e5764834223 94 SUPERFAMILY SSF54975 3 93 1.09E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CPF12_RS00975 46247d5c4538b115d3a26e5764834223 94 Gene3D G3DSA:3.30.70.100 2 94 7.4E-24 T 28-03-2018 CPF12_RS00975 46247d5c4538b115d3a26e5764834223 94 PRINTS PR00112 Acylphosphatase signature 6 21 2.6E-5 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CPF12_RS00975 46247d5c4538b115d3a26e5764834223 94 PRINTS PR00112 Acylphosphatase signature 27 52 2.6E-5 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CPF12_RS00975 46247d5c4538b115d3a26e5764834223 94 Pfam PF00708 Acylphosphatase 7 92 5.9E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CPF12_RS05445 43da42224bae1398ed09a4e3ad4211f2 253 Gene3D G3DSA:3.40.50.300 2 253 1.1E-61 T 28-03-2018 CPF12_RS05445 43da42224bae1398ed09a4e3ad4211f2 253 Pfam PF13614 AAA domain 3 178 3.3E-69 T 28-03-2018 IPR025669 AAA domain CPF12_RS05445 43da42224bae1398ed09a4e3ad4211f2 253 SUPERFAMILY SSF52540 1 251 1.3E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05445 43da42224bae1398ed09a4e3ad4211f2 253 PIRSF PIRSF009320 1 65 8.9E-14 T 28-03-2018 CPF12_RS05445 43da42224bae1398ed09a4e3ad4211f2 253 PIRSF PIRSF009320 90 253 3.0E-7 T 28-03-2018 CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 Gene3D G3DSA:3.20.20.100 1 325 3.0E-101 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 Pfam PF00248 Aldo/keto reductase family 15 316 7.6E-77 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 SUPERFAMILY SSF51430 1 322 1.57E-104 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 PRINTS PR00069 Aldo-keto reductase signature 170 187 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 PRINTS PR00069 Aldo-keto reductase signature 47 71 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 PRINTS PR00069 Aldo-keto reductase signature 113 131 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS11605 4baed49742b0d53c8271491e46b2ed5a 326 PRINTS PR00069 Aldo-keto reductase signature 250 274 4.2E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS10475 b73f8830e44741fa4d1307e18ed657f1 194 Pfam PF13731 WxL domain surface cell wall-binding 39 192 1.0E-23 T 28-03-2018 IPR027994 WxL domain CPF12_RS04180 1f35cb97e7d40334f91bd713a8662493 348 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 274 293 6.5E-5 T 28-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CPF12_RS04180 1f35cb97e7d40334f91bd713a8662493 348 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 176 190 6.5E-5 T 28-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CPF12_RS04180 1f35cb97e7d40334f91bd713a8662493 348 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 254 268 6.5E-5 T 28-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CPF12_RS04180 1f35cb97e7d40334f91bd713a8662493 348 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 112 126 6.5E-5 T 28-03-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD CPF12_RS04180 1f35cb97e7d40334f91bd713a8662493 348 Pfam PF12679 ABC-2 family transporter protein 5 272 2.6E-6 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Pfam PF00271 Helicase conserved C-terminal domain 436 545 3.0E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Hamap MF_00204 UvrABC system protein B [uvrB]. 4 649 44.071 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Pfam PF04851 Type III restriction enzyme, res subunit 17 120 3.8E-11 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Gene3D G3DSA:3.40.50.300 415 589 9.1E-34 T 28-03-2018 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Pfam PF02151 UvrB/uvrC motif 616 648 1.0E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Pfam PF12344 Ultra-violet resistance protein B 552 593 9.6E-23 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 SMART SM00490 460 546 1.2E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 SUPERFAMILY SSF52540 37 81 2.88E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 SUPERFAMILY SSF52540 470 592 2.88E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 SMART SM00487 10 426 5.1E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 SUPERFAMILY SSF52540 4 415 1.88E-136 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Gene3D G3DSA:3.40.50.300 6 411 1.5E-29 T 28-03-2018 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 Gene3D G3DSA:4.10.860.10 614 648 4.9E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 647 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CPF12_RS06740 0897117b6cfcbde7b7b55a5a11d4c4b3 653 SUPERFAMILY SSF46600 615 648 1.11E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS04285 4de7673ed3d21096e551899ba391591d 291 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 262 1.3E-113 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CPF12_RS04285 4de7673ed3d21096e551899ba391591d 291 Pfam PF00483 Nucleotidyl transferase 5 260 4.4E-32 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CPF12_RS04285 4de7673ed3d21096e551899ba391591d 291 Gene3D G3DSA:3.90.550.10 1 290 9.3E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS04285 4de7673ed3d21096e551899ba391591d 291 SUPERFAMILY SSF53448 1 275 1.28E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 28-03-2018 IPR020845 AMP-binding, conserved site CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Gene3D G3DSA:3.30.300.30 381 478 2.6E-30 T 28-03-2018 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Gene3D G3DSA:2.30.38.10 305 380 3.5E-14 T 28-03-2018 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Gene3D G3DSA:3.40.50.980 156 304 1.2E-31 T 28-03-2018 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Pfam PF13193 AMP-binding enzyme C-terminal domain 396 469 3.5E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Pfam PF00501 AMP-binding enzyme 9 387 1.1E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Gene3D G3DSA:3.40.50.980 1 155 1.4E-29 T 28-03-2018 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 SUPERFAMILY SSF56801 3 478 7.2E-120 T 28-03-2018 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 28 473 7.5E-131 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CPF12_RS10240 690d748a84fb092aa168c291233298ee 478 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 3 478 41.047 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.0E-33 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 SUPERFAMILY SSF52922 189 325 4.58E-35 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 Gene3D G3DSA:3.40.50.970 2 194 1.4E-71 T 28-03-2018 CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 Gene3D G3DSA:3.40.50.920 195 326 2.1E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 SUPERFAMILY SSF52518 2 204 8.03E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.9E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS01795 06e61b4962252b3cebcd3b8901d0d79a 327 SMART SM00861 4 179 5.0E-69 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 SMART SM01217 585 655 7.8E-33 T 28-03-2018 IPR026891 Fibronectin type III-like domain CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 116 132 5.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 147 163 5.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 217 235 5.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 70 89 5.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 33 49 5.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 Gene3D G3DSA:3.40.50.1700 300 548 3.7E-77 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 SUPERFAMILY SSF51445 5 314 2.95E-89 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 Gene3D G3DSA:2.60.40.10 549 669 2.6E-39 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 SUPERFAMILY SSF52279 315 551 8.76E-50 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 Gene3D G3DSA:3.20.20.300 2 289 1.4E-92 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 33 285 4.5E-51 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 315 548 3.6E-52 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS07270 9db674933846f80ca5a8431904103e73 756 Pfam PF14310 Fibronectin type III-like domain 585 655 2.1E-25 T 28-03-2018 IPR026891 Fibronectin type III-like domain CPF12_RS00550 376f6dd8579e62ec549f146a1c721d98 293 Pfam PF13527 Acetyltransferase (GNAT) domain 30 130 2.3E-14 T 28-03-2018 CPF12_RS00550 376f6dd8579e62ec549f146a1c721d98 293 Gene3D G3DSA:3.40.630.30 4 151 1.3E-13 T 28-03-2018 CPF12_RS00550 376f6dd8579e62ec549f146a1c721d98 293 SUPERFAMILY SSF55729 16 256 2.7E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS09910 624fcb337c6480b611ae7f0faf1720ab 196 SUPERFAMILY SSF58113 100 193 7.06E-5 T 28-03-2018 CPF12_RS09910 624fcb337c6480b611ae7f0faf1720ab 196 Pfam PF12732 YtxH-like protein 14 158 5.9E-9 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH CPF12_RS09910 624fcb337c6480b611ae7f0faf1720ab 196 Gene3D G3DSA:1.20.120.20 33 196 9.8E-13 T 28-03-2018 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 303 9.2E-121 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 Gene3D G3DSA:3.90.110.10 147 310 1.1E-45 T 28-03-2018 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 310 43.498 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 PIRSF PIRSF000102 2 310 3.4E-105 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 SUPERFAMILY SSF51735 3 147 2.02E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 Gene3D G3DSA:3.40.50.720 7 146 2.8E-37 T 28-03-2018 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 308 9.8E-32 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 145 5.2E-45 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 SUPERFAMILY SSF56327 146 309 6.34E-51 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 2.7E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 2.7E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 2.7E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 2.7E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05225 519b7fe20fb5cec5509e8a006f904306 310 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 2.7E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.801 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 SUPERFAMILY SSF54814 2 105 2.88E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 Gene3D G3DSA:3.30.1140.32 107 206 1.3E-36 T 28-03-2018 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.0E-93 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 Pfam PF07650 KH domain 38 109 8.4E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 SMART SM00322 59 124 5.7E-8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 SUPERFAMILY SSF54821 107 205 1.44E-37 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.8E-39 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 Gene3D G3DSA:3.30.300.20 17 106 2.2E-30 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS06090 3ca5deca20dc134f22e35c4fd5a4bd19 220 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06655 74c609e66799abc4f9e386984087c42d 286 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 219 272 2.7E-16 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CPF12_RS06655 74c609e66799abc4f9e386984087c42d 286 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 212 2.1E-58 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CPF12_RS06655 74c609e66799abc4f9e386984087c42d 286 PIRSF PIRSF006483 1 280 3.4E-76 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CPF12_RS05835 722a7e99242c60777efd24ad59a68546 123 TIGRFAM TIGR00526 folB_dom: FolB domain 1 120 1.9E-29 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CPF12_RS05835 722a7e99242c60777efd24ad59a68546 123 SUPERFAMILY SSF55620 2 120 3.89E-35 T 28-03-2018 CPF12_RS05835 722a7e99242c60777efd24ad59a68546 123 SMART SM00905 4 117 2.0E-42 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CPF12_RS05835 722a7e99242c60777efd24ad59a68546 123 Gene3D G3DSA:3.30.1130.10 1 119 1.3E-31 T 28-03-2018 CPF12_RS05835 722a7e99242c60777efd24ad59a68546 123 Pfam PF02152 Dihydroneopterin aldolase 4 116 3.4E-31 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CPF12_RS05835 722a7e99242c60777efd24ad59a68546 123 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 1.4E-32 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CPF12_RS04465 75644acc6b5a6191a6e8e97db6fabd68 183 SUPERFAMILY SSF52218 3 170 1.29E-21 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS04465 75644acc6b5a6191a6e8e97db6fabd68 183 Pfam PF03358 NADPH-dependent FMN reductase 3 141 4.7E-24 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CPF12_RS04465 75644acc6b5a6191a6e8e97db6fabd68 183 Gene3D G3DSA:3.40.50.360 1 174 2.7E-23 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 SUPERFAMILY SSF49899 233 450 9.72E-29 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 683 803 2.4E-8 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 457 571 8.5E-8 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 Pfam PF00139 Legume lectin domain 235 460 1.5E-10 T 28-03-2018 IPR001220 Legume lectin domain GO:0030246 CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 Gene3D G3DSA:2.60.40.10 584 695 6.3E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 Gene3D G3DSA:2.60.40.740 696 806 2.3E-18 T 28-03-2018 CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 SUPERFAMILY SSF49478 596 654 5.89E-6 T 28-03-2018 CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 Pfam PF01345 Domain of unknown function DUF11 686 777 4.1E-11 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 Gene3D G3DSA:2.60.40.740 474 583 1.7E-11 T 28-03-2018 CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 Gene3D G3DSA:2.60.120.200 227 473 4.1E-39 T 28-03-2018 CPF12_RS04040 32e3701dc2e249cf141ac6cf1daf8ced 942 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 688 738 6.0E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CPF12_RS06765 a94ce00e84ebaf2704c4f5ed4a7a04d1 116 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 106 1.8E-25 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 3.0E-37 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 3.0E-37 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 73 91 3.0E-37 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 3.0E-37 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 3.0E-37 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 PIRSF PIRSF006160 1 152 1.2E-61 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 147 1.0E-51 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 145 1.2E-53 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 Gene3D G3DSA:3.30.1360.80 1 142 4.0E-57 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 SUPERFAMILY SSF63411 1 148 2.29E-58 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS03290 e8b3fb8f62bc21c22b1581a831ea3e2c 153 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 152 36.242 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SMART SM00896 710 802 1.9E-38 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SUPERFAMILY SSF55681 476 697 3.23E-51 T 28-03-2018 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SUPERFAMILY SSF56037 210 401 3.4E-60 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Pfam PF03484 tRNA synthetase B5 domain 417 480 4.3E-17 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SMART SM00873 222 395 7.5E-74 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Pfam PF01588 Putative tRNA binding domain 46 129 8.2E-22 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Gene3D G3DSA:3.50.40.10 205 406 5.1E-59 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Gene3D G3DSA:3.30.56.10 1 54 3.1E-7 T 28-03-2018 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Gene3D G3DSA:3.30.930.10 498 697 1.1E-36 T 28-03-2018 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SUPERFAMILY SSF46955 414 484 1.46E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 802 2.0E-245 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Pfam PF03483 B3/4 domain 223 394 7.0E-59 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Gene3D G3DSA:2.40.50.140 55 161 2.7E-40 T 28-03-2018 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 42.298 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SUPERFAMILY SSF54991 706 802 4.97E-27 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 802 3.6E-26 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Gene3D G3DSA:3.30.70.380 706 802 2.6E-23 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SMART SM00874 412 480 3.5E-24 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 Gene3D G3DSA:3.30.56.10 410 484 1.9E-21 T 28-03-2018 CPF12_RS02365 c9d57843124707b217993dcc72ea0e08 802 SUPERFAMILY SSF50249 42 195 4.65E-43 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 SMART SM00962 101 297 2.8E-121 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 447 35.492 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Gene3D G3DSA:3.40.50.300 93 298 3.4E-43 T 28-03-2018 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 SUPERFAMILY SSF47446 329 431 2.78E-38 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 SMART SM00963 2 87 4.7E-33 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 SMART SM00382 100 277 2.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 SUPERFAMILY SSF52540 43 354 4.7E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Pfam PF02978 Signal peptide binding domain 329 427 4.2E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Gene3D G3DSA:1.20.120.140 1 92 6.7E-30 T 28-03-2018 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Gene3D G3DSA:1.10.260.30 328 432 3.2E-39 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 8.8E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 1.2E-79 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11620 c639d9d6451b987ae0f4a4882835cad6 454 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 5.4E-193 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 Gene3D G3DSA:1.20.5.170 200 222 1.0E-10 T 28-03-2018 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 413 2.6E-18 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 Gene3D G3DSA:3.40.50.720 1 196 2.6E-36 T 28-03-2018 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 181 1.6E-36 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 SUPERFAMILY SSF52413 300 393 4.84E-23 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 Gene3D G3DSA:3.40.50.720 223 422 2.6E-50 T 28-03-2018 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 SUPERFAMILY SSF48179 200 291 1.17E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 289 2.5E-24 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 PIRSF PIRSF000124 6 423 2.0E-55 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 PIRSF PIRSF500136 1 424 8.0E-143 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 SMART SM00984 316 417 9.3E-19 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 SUPERFAMILY SSF51735 7 191 1.18E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08855 565941b9973d1e5308b97384e3e3b5e2 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 401 1.3E-117 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CPF12_RS11050 251fe4500b0b693fd87e7657763e6d88 176 Gene3D G3DSA:3.40.630.30 59 172 6.0E-18 T 28-03-2018 CPF12_RS11050 251fe4500b0b693fd87e7657763e6d88 176 SUPERFAMILY SSF55729 9 165 1.34E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS11050 251fe4500b0b693fd87e7657763e6d88 176 Pfam PF13302 Acetyltransferase (GNAT) domain 65 156 2.3E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS03430 1b061dc2ca570d3a0c3019162af5b777 290 SUPERFAMILY SSF56784 1 287 8.16E-61 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03430 1b061dc2ca570d3a0c3019162af5b777 290 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 282 1.2E-58 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03430 1b061dc2ca570d3a0c3019162af5b777 290 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 255 4.1E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS03430 1b061dc2ca570d3a0c3019162af5b777 290 ProSitePatterns PS01229 Hypothetical cof family signature 2. 236 258 - T 28-03-2018 CPF12_RS03430 1b061dc2ca570d3a0c3019162af5b777 290 Gene3D G3DSA:3.40.50.1000 1 290 9.7E-40 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03430 1b061dc2ca570d3a0c3019162af5b777 290 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 282 3.7E-57 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS06140 85cf345e2e147b80baf2ea46cf890115 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 119 2.2E-47 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06140 85cf345e2e147b80baf2ea46cf890115 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 119 28.177 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06140 85cf345e2e147b80baf2ea46cf890115 119 SUPERFAMILY SSF53137 7 117 1.4E-50 T 28-03-2018 CPF12_RS06140 85cf345e2e147b80baf2ea46cf890115 119 Gene3D G3DSA:3.30.420.100 2 119 1.1E-40 T 28-03-2018 CPF12_RS06140 85cf345e2e147b80baf2ea46cf890115 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 119 1.6E-43 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.5E-63 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 Gene3D G3DSA:1.10.455.10 6 156 5.5E-58 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 SUPERFAMILY SSF47973 1 149 2.75E-58 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.431 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 PIRSF PIRSF002122 4 156 3.1E-55 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CPF12_RS06035 c566955faa6ee0a64015a9c5ac8ec94c 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 8.7E-69 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS11025 7832d94709d4c2c30ee53f1c414c63be 481 Pfam PF00324 Amino acid permease 15 463 9.2E-127 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CPF12_RS11025 7832d94709d4c2c30ee53f1c414c63be 481 PIRSF PIRSF006060 1 481 4.5E-80 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CPF12_RS11025 7832d94709d4c2c30ee53f1c414c63be 481 ProSitePatterns PS00218 Amino acid permeases signature. 40 71 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CPF12_RS04910 79ce1b2c33e65cdb8b3bf5b762b38097 105 SUPERFAMILY SSF52794 2 100 1.92E-31 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS04910 79ce1b2c33e65cdb8b3bf5b762b38097 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 95 1.5E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS04910 79ce1b2c33e65cdb8b3bf5b762b38097 105 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 88 2.8E-28 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CPF12_RS04910 79ce1b2c33e65cdb8b3bf5b762b38097 105 Gene3D G3DSA:3.40.50.2300 2 101 1.7E-34 T 28-03-2018 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 SUPERFAMILY SSF51735 122 280 5.63E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 Gene3D G3DSA:3.40.50.10860 10 139 6.3E-48 T 28-03-2018 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 120 2.8E-39 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 Gene3D G3DSA:3.40.50.720 140 263 3.3E-41 T 28-03-2018 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 1.3E-71 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 SUPERFAMILY SSF53223 2 121 2.59E-39 T 28-03-2018 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 282 38.998 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.2E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS01485 fb844aa2f102cef4fc2ce8ff5038add7 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 Gene3D G3DSA:1.10.357.10 59 193 3.6E-18 T 28-03-2018 CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 SUPERFAMILY SSF48498 81 192 2.08E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 Gene3D G3DSA:1.10.10.60 1 58 3.1E-15 T 28-03-2018 CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 SUPERFAMILY SSF46689 1 72 7.7E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CPF12_RS03145 24ca6f9ff0e4ad4dea3ab4d84b0d0520 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 1.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Gene3D G3DSA:3.30.1360.120 1 127 9.3E-45 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 SUPERFAMILY SSF52540 204 378 1.49E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 SUPERFAMILY SSF52540 80 169 1.49E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Pfam PF12631 MnmE helical domain 129 458 7.4E-60 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Pfam PF01926 50S ribosome-binding GTPase 227 338 2.2E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Gene3D G3DSA:1.20.120.430 289 461 2.9E-29 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 PRINTS PR00449 Transforming protein P21 ras signature 224 245 2.5E-5 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 PRINTS PR00449 Transforming protein P21 ras signature 328 341 2.5E-5 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 PRINTS PR00449 Transforming protein P21 ras signature 264 286 2.5E-5 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 227 374 2.2E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 126 4.7E-41 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 461 3.4E-129 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 461 33.889 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 SUPERFAMILY SSF116878 127 227 3.66E-49 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 SUPERFAMILY SSF116878 386 461 3.66E-49 T 28-03-2018 CPF12_RS05475 1bada71a59b3d34201a0d11e9bee2f50 461 Gene3D G3DSA:1.20.120.430 128 288 2.7E-30 T 28-03-2018 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 Gene3D G3DSA:3.30.930.10 158 501 1.6E-100 T 28-03-2018 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 Pfam PF00152 tRNA synthetases class II (D, K and N) 165 501 6.2E-78 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 211 1.6E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 264 281 1.6E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.6E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 259 1.6E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 1.6E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 Pfam PF01336 OB-fold nucleic acid binding domain 71 147 1.3E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 23 506 44.315 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 SUPERFAMILY SSF55681 164 502 5.18E-118 T 28-03-2018 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 Gene3D G3DSA:2.40.50.140 17 157 1.4E-41 T 28-03-2018 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 17 504 5.8E-211 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CPF12_RS05845 e067ba8d4f0c9e5100e0661e37436b6d 506 SUPERFAMILY SSF50249 16 157 1.1E-43 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 PIRSF PIRSF000447 1 410 6.4E-139 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 366 6.3E-34 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 SUPERFAMILY SSF53901 213 407 4.02E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 244 2.3E-55 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 Gene3D G3DSA:3.40.47.10 257 408 1.6E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 SUPERFAMILY SSF53901 3 251 3.15E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 SMART SM00825 Beta-ketoacyl synthase 5 410 7.6E-16 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 151 167 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CPF12_RS04685 492fa9da4fd74e899bb1633b73c72af1 410 Gene3D G3DSA:3.40.47.10 1 256 9.9E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 SUPERFAMILY SSF52096 10 193 5.74E-73 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.6E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.6E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.6E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.6E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.6E-53 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.038 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 8.7E-102 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 Pfam PF00574 Clp protease 12 191 2.9E-88 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CPF12_RS06855 45b5cd91032dd573b5839f6ba4cd5e7f 197 Gene3D G3DSA:3.90.226.10 2 194 2.3E-46 T 28-03-2018 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 SUPERFAMILY SSF81338 6 241 5.63E-69 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 Pfam PF00230 Major intrinsic protein 6 236 6.5E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 PRINTS PR00783 Major intrinsic protein family signature 50 74 8.6E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 PRINTS PR00783 Major intrinsic protein family signature 142 160 8.6E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 PRINTS PR00783 Major intrinsic protein family signature 8 27 8.6E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 PRINTS PR00783 Major intrinsic protein family signature 172 194 8.6E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 PRINTS PR00783 Major intrinsic protein family signature 219 239 8.6E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 PRINTS PR00783 Major intrinsic protein family signature 87 106 8.6E-45 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 Gene3D G3DSA:1.20.1080.10 1 244 1.2E-83 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 TIGRFAM TIGR00861 MIP: MIP family channel proteins 13 236 2.4E-56 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS04885 fc8a3bbe9279b12472dca7583a4af727 288 ProSitePatterns PS00221 MIP family signature. 68 76 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 Pfam PF00271 Helicase conserved C-terminal domain 207 316 1.4E-31 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 Gene3D G3DSA:3.40.50.300 1 200 1.1E-59 T 28-03-2018 CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 Gene3D G3DSA:3.40.50.300 201 496 1.1E-48 T 28-03-2018 CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 SMART SM00487 2 199 5.2E-68 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 498 42.749 T 28-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 130 138 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 SMART SM00490 235 316 9.2E-36 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 Pfam PF00270 DEAD/DEAH box helicase 7 171 8.6E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS09010 2da8a8bc049a8ccbb5ad9884ce44c3af 498 SUPERFAMILY SSF52540 50 337 6.99E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 SUPERFAMILY SSF53067 83 206 3.56E-9 T 28-03-2018 CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 Gene3D G3DSA:1.10.10.10 13 82 1.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 Gene3D G3DSA:3.30.420.40 83 202 3.7E-7 T 28-03-2018 CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 Gene3D G3DSA:3.30.420.40 203 399 5.9E-26 T 28-03-2018 CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 SUPERFAMILY SSF53067 227 397 2.87E-25 T 28-03-2018 CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 Pfam PF00480 ROK family 88 382 7.5E-23 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS04215 eb4cec6e6553972f4c1077e8bbca8b87 399 SUPERFAMILY SSF46785 22 89 5.97E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 SMART SM00962 120 321 9.7E-121 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 Gene3D G3DSA:1.20.120.140 14 86 1.7E-22 T 28-03-2018 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 Gene3D G3DSA:1.20.120.140 233 329 2.9E-23 T 28-03-2018 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 SUPERFAMILY SSF47364 18 96 5.5E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 2.9E-79 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 6.8E-15 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 64.229 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 SUPERFAMILY SSF52540 121 320 1.35E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 47 320 1.7E-116 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 SMART SM00382 119 299 7.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 Gene3D G3DSA:3.40.50.300 87 232 4.4E-21 T 28-03-2018 CPF12_RS11550 d328f1c9f2349d0661b49cf6d938694b 330 SMART SM00963 22 103 1.6E-25 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 2.6E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 2.6E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 2.6E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 2.6E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 2.6E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 2.6E-67 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 280 7.3E-143 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 2 289 1.3E-156 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 SUPERFAMILY SSF55681 1 280 4.47E-126 T 28-03-2018 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 56.414 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 Gene3D G3DSA:1.20.58.180 206 282 8.6E-34 T 28-03-2018 CPF12_RS11085 b9c15198e3ebb2887815a6bfa73a1622 291 Gene3D G3DSA:3.30.930.10 1 204 7.4E-79 T 28-03-2018 CPF12_RS06910 dc64350f8292c8e2c3f1717c04e1a903 251 Gene3D G3DSA:3.20.20.70 1 251 2.4E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS06910 dc64350f8292c8e2c3f1717c04e1a903 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06910 dc64350f8292c8e2c3f1717c04e1a903 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 239 8.2E-57 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06910 dc64350f8292c8e2c3f1717c04e1a903 251 SUPERFAMILY SSF51351 1 248 3.8E-90 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06910 dc64350f8292c8e2c3f1717c04e1a903 251 Pfam PF00121 Triosephosphate isomerase 5 246 2.7E-89 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06910 dc64350f8292c8e2c3f1717c04e1a903 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 39.296 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 Gene3D G3DSA:2.30.40.10 18 77 2.7E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 SUPERFAMILY SSF51338 15 73 1.17E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 SUPERFAMILY SSF51338 321 356 1.17E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 SUPERFAMILY SSF51556 73 318 8.39E-30 T 28-03-2018 IPR032466 Metal-dependent hydrolase CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 Gene3D G3DSA:3.20.20.140 78 248 3.2E-13 T 28-03-2018 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 Gene3D G3DSA:2.30.40.10 249 361 1.1E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 Pfam PF01979 Amidohydrolase family 69 352 1.1E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 Pfam PF13382 Adenine deaminase C-terminal domain 403 568 5.1E-58 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 TIGRFAM TIGR01178 ade: adenine deaminase 22 574 3.0E-177 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CPF12_RS03615 2e3aec7570349c4f8f9100578ca66131 580 Hamap MF_01518 Adenine deaminase [ade]. 22 575 36.748 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CPF12_RS06460 ea4797e8f54bf9a305e44d2500f6d4a5 382 Gene3D G3DSA:3.40.50.2000 209 354 2.1E-32 T 28-03-2018 CPF12_RS06460 ea4797e8f54bf9a305e44d2500f6d4a5 382 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 8 370 2.3E-157 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CPF12_RS06460 ea4797e8f54bf9a305e44d2500f6d4a5 382 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 29 367 2.1E-117 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CPF12_RS06460 ea4797e8f54bf9a305e44d2500f6d4a5 382 Gene3D G3DSA:3.40.50.2000 8 208 7.4E-75 T 28-03-2018 CPF12_RS06460 ea4797e8f54bf9a305e44d2500f6d4a5 382 SUPERFAMILY SSF53756 7 371 2.67E-134 T 28-03-2018 CPF12_RS01960 8d55ff622c64df7fcb862d0b80a4f41e 231 Gene3D G3DSA:1.20.144.10 20 225 2.2E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CPF12_RS01960 8d55ff622c64df7fcb862d0b80a4f41e 231 SUPERFAMILY SSF48317 11 213 1.14E-36 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CPF12_RS01960 8d55ff622c64df7fcb862d0b80a4f41e 231 SMART SM00014 90 200 5.0E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CPF12_RS01960 8d55ff622c64df7fcb862d0b80a4f41e 231 Pfam PF01569 PAP2 superfamily 92 204 2.5E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CPF12_RS00270 e85fb93061a42c56be301416f415b3da 287 Gene3D G3DSA:1.10.10.60 204 265 6.5E-8 T 28-03-2018 CPF12_RS00270 e85fb93061a42c56be301416f415b3da 287 Pfam PF13556 PucR C-terminal helix-turn-helix domain 238 283 1.5E-14 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CPF12_RS00270 e85fb93061a42c56be301416f415b3da 287 SUPERFAMILY SSF46689 210 264 8.06E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS04060 eca9d996fdf0567c5e955c06948467c0 347 Gene3D G3DSA:2.60.40.1120 250 311 0.012 T 28-03-2018 CPF12_RS04060 eca9d996fdf0567c5e955c06948467c0 347 Pfam PF06030 Bacterial protein of unknown function (DUF916) 33 151 2.3E-36 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CPF12_RS04060 eca9d996fdf0567c5e955c06948467c0 347 Gene3D G3DSA:2.60.40.1710 42 164 3.4E-6 T 28-03-2018 CPF12_RS04060 eca9d996fdf0567c5e955c06948467c0 347 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 164 300 1.5E-51 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 SUPERFAMILY SSF52833 2 105 7.1E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 Pfam PF00085 Thioredoxin 4 103 4.5E-29 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 PIRSF PIRSF000077 1 105 5.0E-40 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 104 2.1E-36 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 Gene3D G3DSA:3.40.30.10 1 105 5.8E-34 T 28-03-2018 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 PRINTS PR00421 Thioredoxin family signature 21 29 1.4E-7 T 28-03-2018 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 PRINTS PR00421 Thioredoxin family signature 29 38 1.4E-7 T 28-03-2018 CPF12_RS02345 11ef78580d315e121cf01d40bbd2c24e 105 PRINTS PR00421 Thioredoxin family signature 69 80 1.4E-7 T 28-03-2018 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 324 3.6E-10 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SMART SM00316 624 694 5.9E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Gene3D G3DSA:3.30.230.70 12 251 9.1E-50 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF55666 137 230 1.54E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF50249 624 701 2.5E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF03725 3' exoribonuclease family, domain 2 146 209 1.1E-12 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF03725 3' exoribonuclease family, domain 2 463 532 1.2E-5 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 695 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF00013 KH domain 560 616 2.2E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 697 30.058 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Gene3D G3DSA:3.30.1370.10 567 621 1.9E-13 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF54211 298 491 5.57E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF46915 238 324 1.07E-12 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Gene3D G3DSA:1.10.10.400 252 311 1.2E-17 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF54211 7 143 2.94E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Gene3D G3DSA:2.40.50.140 622 700 4.4E-21 T 28-03-2018 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Gene3D G3DSA:3.30.230.70 312 566 2.5E-59 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF01138 3' exoribonuclease family, domain 1 327 460 2.6E-19 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF01138 3' exoribonuclease family, domain 1 14 143 1.3E-16 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SMART SM00322 556 621 1.8E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF54791 559 644 4.55E-22 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 SUPERFAMILY SSF55666 454 552 7.29E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 PIRSF PIRSF005499 1 703 1.2E-287 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CPF12_RS12155 2ff20a71cf352720f213605691529248 703 Pfam PF00575 S1 RNA binding domain 623 694 1.2E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1127 1192 3.57E-9 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1685 1749 6.67E-9 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1406 1471 4.71E-9 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1499 1563 1.33E-7 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1575 1669 4.4E-27 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1297 1390 3.1E-29 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1391 1483 1.2E-28 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1762 1853 9.6E-27 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 2040 2165 2.6E-29 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1670 1761 1.0E-28 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1854 1946 9.3E-27 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1111 1204 1.8E-29 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1205 1296 6.1E-28 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1013 1110 7.8E-24 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1484 1574 7.6E-28 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 Gene3D G3DSA:2.60.40.810 1947 2039 2.0E-26 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 2057 2122 9.42E-9 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1778 1842 5.49E-7 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1871 1935 5.49E-7 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1592 1657 1.84E-7 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2154 2184 5.4E-4 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1034 1098 7.45E-7 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1313 1378 8.63E-9 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1964 2029 7.06E-8 T 28-03-2018 CPF12_RS06960 5196ba352486aebc028f39e0f20fd0aa 2189 SUPERFAMILY SSF49478 1220 1285 1.65E-8 T 28-03-2018 CPF12_RS07345 9acbe63591e5e17de9bc51821d90e8c7 71 SUPERFAMILY SSF52218 1 69 8.38E-11 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS07345 9acbe63591e5e17de9bc51821d90e8c7 71 Gene3D G3DSA:3.40.50.360 1 70 1.2E-7 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS07345 9acbe63591e5e17de9bc51821d90e8c7 71 Pfam PF02525 Flavodoxin-like fold 2 65 2.1E-8 T 28-03-2018 IPR003680 Flavodoxin-like fold CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.5E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.5E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.5E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.9E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 Gene3D G3DSA:3.30.1340.10 1 88 1.1E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 SUPERFAMILY SSF55594 1 83 4.97E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS08570 1740c30034a95ecb5ed794eb25cd23f1 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 2.2E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 Gene3D G3DSA:3.30.70.260 308 391 2.5E-11 T 28-03-2018 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 96 273 7.1E-41 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 Gene3D G3DSA:3.40.50.720 101 277 1.7E-38 T 28-03-2018 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 306 8.9E-19 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 SUPERFAMILY SSF51735 88 275 4.71E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 140 167 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 SUPERFAMILY SSF52283 25 94 2.27E-18 T 28-03-2018 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 SUPERFAMILY SSF52283 129 151 2.27E-18 T 28-03-2018 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 Gene3D G3DSA:3.40.50.720 12 100 1.7E-18 T 28-03-2018 CPF12_RS00890 e1a37d8d5bc5880b7f69de0494297df6 395 SUPERFAMILY SSF55021 309 391 3.16E-12 T 28-03-2018 CPF12_RS00475 8874f96dae0dceb02a158ccd9bf97f66 341 Pfam PF01212 Beta-eliminating lyase 19 239 4.1E-27 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CPF12_RS00475 8874f96dae0dceb02a158ccd9bf97f66 341 SUPERFAMILY SSF53383 1 341 1.05E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS00475 8874f96dae0dceb02a158ccd9bf97f66 341 Gene3D G3DSA:3.40.640.10 1 254 1.3E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS00475 8874f96dae0dceb02a158ccd9bf97f66 341 Gene3D G3DSA:3.90.1150.10 255 341 2.5E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS02090 abe92f0067935b94fd46149b5a0e3d59 92 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 8 77 7.0E-26 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CPF12_RS02090 abe92f0067935b94fd46149b5a0e3d59 92 PIRSF PIRSF031653 2 91 2.8E-26 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CPF12_RS11895 9e0b72196bd9b6694bbe01dfbb1a009d 122 Gene3D G3DSA:1.20.1500.10 6 114 3.1E-22 T 28-03-2018 IPR023378 YheA/YmcA-like domain CPF12_RS11895 9e0b72196bd9b6694bbe01dfbb1a009d 122 PIRSF PIRSF021287 1 121 6.8E-40 T 28-03-2018 IPR016783 Biofilm formation YmcA CPF12_RS11895 9e0b72196bd9b6694bbe01dfbb1a009d 122 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 7 108 3.2E-16 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CPF12_RS11895 9e0b72196bd9b6694bbe01dfbb1a009d 122 SUPERFAMILY SSF158622 1 115 2.09E-24 T 28-03-2018 IPR023378 YheA/YmcA-like domain CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 178 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 Gene3D G3DSA:3.40.50.720 1 112 4.9E-26 T 28-03-2018 CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 SUPERFAMILY SSF52283 1 132 1.49E-23 T 28-03-2018 CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 290 1.6E-62 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 SUPERFAMILY SSF51735 101 290 2.1E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 321 3.8E-22 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CPF12_RS03225 610f3cae19be7c2541686fadc6c98035 322 Gene3D G3DSA:3.40.50.720 113 293 1.4E-57 T 28-03-2018 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 12 750 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 Pfam PF01228 Glycine radical 625 731 2.8E-42 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 Gene3D G3DSA:3.20.70.20 2 750 2.4E-291 T 28-03-2018 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 PIRSF PIRSF000379 8 750 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 Pfam PF02901 Pyruvate formate lyase-like 28 609 2.4E-207 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 SUPERFAMILY SSF51998 9 750 1.68E-281 T 28-03-2018 CPF12_RS04200 2105906652fc4d994fcc6a2668248a8a 750 ProSitePatterns PS00850 Glycine radical domain signature. 720 728 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CPF12_RS10570 17256da719612917c8c7124347e6f607 161 Gene3D G3DSA:3.40.430.10 1 161 1.9E-47 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 SUPERFAMILY SSF53597 1 161 4.06E-52 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 PIRSF PIRSF000194 1 161 7.1E-51 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 Pfam PF00186 Dihydrofolate reductase 1 160 3.6E-56 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.1E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.1E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.1E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CPF12_RS10570 17256da719612917c8c7124347e6f607 161 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.1E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 Pfam PF00293 NUDIX domain 47 151 8.7E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 SUPERFAMILY SSF55811 12 152 1.18E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 Gene3D G3DSA:1.10.287.1030 4 33 4.6E-11 T 28-03-2018 CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 SUPERFAMILY SSF46785 206 267 4.22E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 Gene3D G3DSA:3.90.79.10 34 203 4.0E-39 T 28-03-2018 CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 Gene3D G3DSA:1.10.10.10 204 270 3.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00545 7c6809c4f6276a458a62f43215ba2395 274 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CPF12_RS10955 5daa28607c39b0751fbee1a4a45d1f88 129 Gene3D G3DSA:3.30.429.10 1 129 4.7E-30 T 28-03-2018 CPF12_RS10955 5daa28607c39b0751fbee1a4a45d1f88 129 SUPERFAMILY SSF55331 2 128 6.96E-38 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CPF12_RS10955 5daa28607c39b0751fbee1a4a45d1f88 129 Pfam PF14552 Tautomerase enzyme 38 118 8.9E-30 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 Gene3D G3DSA:3.30.450.20 21 167 0.0012 T 28-03-2018 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 SMART SM00387 360 472 4.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 314 1.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 Gene3D G3DSA:3.30.565.10 310 472 2.6E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 Pfam PF00672 HAMP domain 191 237 7.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 SUPERFAMILY SSF47384 233 316 9.61E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 SMART SM00388 249 315 4.6E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 SMART SM00304 189 241 2.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 470 6.5E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 SUPERFAMILY SSF158472 190 238 3.01E-9 T 28-03-2018 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 Gene3D G3DSA:1.10.287.130 232 309 9.0E-15 T 28-03-2018 CPF12_RS09665 b97d752794183ed82cd73cafe7c47095 473 SUPERFAMILY SSF55874 305 470 1.19E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09345 b326efdecb8b00d4dd4120ff369a0050 160 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 13 159 23.081 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CPF12_RS09345 b326efdecb8b00d4dd4120ff369a0050 160 SUPERFAMILY SSF55486 3 159 2.56E-41 T 28-03-2018 CPF12_RS09345 b326efdecb8b00d4dd4120ff369a0050 160 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 156 5.2E-41 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CPF12_RS09345 b326efdecb8b00d4dd4120ff369a0050 160 Gene3D G3DSA:3.40.390.30 2 160 4.1E-47 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CPF12_RS09345 b326efdecb8b00d4dd4120ff369a0050 160 Pfam PF02130 Uncharacterized protein family UPF0054 19 154 3.3E-44 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CPF12_RS09345 b326efdecb8b00d4dd4120ff369a0050 160 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 125 135 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 SUPERFAMILY SSF53720 5 449 9.29E-116 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 Pfam PF00171 Aldehyde dehydrogenase family 10 432 2.0E-85 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 239 250 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 Gene3D G3DSA:3.40.605.10 2 230 1.5E-62 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 PIRSF PIRSF036492 1 460 1.1E-176 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 211 218 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CPF12_RS05395 a8f226de1765e96ed410a313e3edee2e 460 Gene3D G3DSA:3.40.309.10 231 412 1.8E-62 T 28-03-2018 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 SMART SM00421 143 200 9.0E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 Gene3D G3DSA:1.10.10.10 106 207 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 SUPERFAMILY SSF46894 139 204 1.02E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS05390 911adf99697996fd0ee932c631070b33 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 198 1.8E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PRINTS PR00471 Acetate kinase family signature 173 186 3.6E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PRINTS PR00471 Acetate kinase family signature 322 338 3.6E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PRINTS PR00471 Acetate kinase family signature 300 313 3.6E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PRINTS PR00471 Acetate kinase family signature 379 391 3.6E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PRINTS PR00471 Acetate kinase family signature 4 15 3.6E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PRINTS PR00471 Acetate kinase family signature 203 224 3.6E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 SUPERFAMILY SSF53067 1 195 7.12E-67 T 28-03-2018 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 PIRSF PIRSF000722 1 401 5.6E-155 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 Gene3D G3DSA:3.30.420.40 3 195 2.7E-74 T 28-03-2018 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 SUPERFAMILY SSF53067 158 398 1.83E-85 T 28-03-2018 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 Hamap MF_00020 Acetate kinase [ackA]. 1 401 181.745 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 Pfam PF00871 Acetokinase family 3 392 7.5E-156 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 TIGRFAM TIGR00016 ackA: acetate kinase 2 397 8.5E-164 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08950 481c5a72a514fa6a7cf720b152cff7a7 401 Gene3D G3DSA:3.30.420.40 196 401 9.6E-80 T 28-03-2018 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 Gene3D G3DSA:3.40.50.150 2 117 6.1E-9 T 28-03-2018 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 SUPERFAMILY SSF53335 4 112 3.18E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 SUPERFAMILY SSF53335 214 308 3.18E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 308 1.8E-122 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 Pfam PF01795 MraW methylase family 2 308 3.1E-132 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 38.289 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 Gene3D G3DSA:1.10.150.170 118 216 1.8E-37 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 SUPERFAMILY SSF81799 113 214 4.05E-34 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS02045 6bbc42f7332ecc368327c3dd473d6965 311 PIRSF PIRSF004486 1 311 6.1E-109 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS03995 55ce84c9a2e29455bc3b3966fc5a95ce 320 Pfam PF01238 Phosphomannose isomerase type I 6 197 4.5E-36 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CPF12_RS03995 55ce84c9a2e29455bc3b3966fc5a95ce 320 SUPERFAMILY SSF51182 2 313 3.29E-95 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS03995 55ce84c9a2e29455bc3b3966fc5a95ce 320 Gene3D G3DSA:2.60.120.10 228 314 4.2E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS03995 55ce84c9a2e29455bc3b3966fc5a95ce 320 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 107 313 2.3E-40 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CPF12_RS03995 55ce84c9a2e29455bc3b3966fc5a95ce 320 PIRSF PIRSF036894 2 316 1.3E-116 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CPF12_RS03995 55ce84c9a2e29455bc3b3966fc5a95ce 320 Gene3D G3DSA:2.60.120.10 1 223 4.0E-53 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 Gene3D G3DSA:1.20.1110.10 69 342 3.6E-34 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 323 329 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 Pfam PF00702 haloacid dehalogenase-like hydrolase 317 533 1.5E-37 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 SUPERFAMILY SSF81653 124 220 4.32E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 SUPERFAMILY SSF56784 319 339 1.08E-55 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 SUPERFAMILY SSF56784 381 619 1.08E-55 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 69 621 2.0E-182 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00941 Cadmium-transporting ATPase signature 205 219 3.3E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00941 Cadmium-transporting ATPase signature 32 49 3.3E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00941 Cadmium-transporting ATPase signature 49 61 3.3E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00941 Cadmium-transporting ATPase signature 186 202 3.3E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00941 Cadmium-transporting ATPase signature 104 124 3.3E-13 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 538 1.8E-26 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 321 335 1.8E-26 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 1.8E-26 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 554 1.8E-26 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 476 1.8E-26 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 601 3.0E-75 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 69 377 4.1E-94 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 Pfam PF00122 E1-E2 ATPase 120 301 1.1E-46 T 28-03-2018 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 Gene3D G3DSA:3.40.50.1000 472 575 6.3E-19 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 SUPERFAMILY SSF81665 71 123 8.24E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 SUPERFAMILY SSF81665 568 598 8.24E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 SUPERFAMILY SSF81665 221 315 8.24E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS09160 1c1669ee827ae2deb2e747ccbcbdf12a 626 Gene3D G3DSA:3.40.1110.10 343 471 4.5E-32 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CPF12_RS07735 6e592882f3a01181b7305f017146ca73 453 SUPERFAMILY SSF161098 193 438 7.19E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07735 6e592882f3a01181b7305f017146ca73 453 Gene3D G3DSA:1.20.58.370 53 178 7.2E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CPF12_RS07735 6e592882f3a01181b7305f017146ca73 453 SUPERFAMILY SSF160964 98 198 1.18E-8 T 28-03-2018 CPF12_RS07735 6e592882f3a01181b7305f017146ca73 453 Gene3D G3DSA:1.10.3720.10 202 445 1.4E-41 T 28-03-2018 CPF12_RS07735 6e592882f3a01181b7305f017146ca73 453 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 227 440 5.6E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06205 e9da1d8c4970b097d34c89672991b33e 290 SMART SM00382 32 222 1.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06205 e9da1d8c4970b097d34c89672991b33e 290 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 277 7.1E-114 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CPF12_RS06205 e9da1d8c4970b097d34c89672991b33e 290 Gene3D G3DSA:3.40.50.300 2 265 1.0E-64 T 28-03-2018 CPF12_RS06205 e9da1d8c4970b097d34c89672991b33e 290 Pfam PF00005 ABC transporter 23 174 8.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS06205 e9da1d8c4970b097d34c89672991b33e 290 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06205 e9da1d8c4970b097d34c89672991b33e 290 SUPERFAMILY SSF52540 3 237 2.78E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 1.4E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 187 201 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 270 294 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 218 244 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 314 330 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 245 269 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 PRINTS PR01050 Pyruvate kinase family signature 295 313 3.3E-74 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 SUPERFAMILY SSF50800 70 168 2.27E-24 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 Gene3D G3DSA:2.40.33.10 111 167 2.4E-20 T 28-03-2018 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 1.1E-177 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 SUPERFAMILY SSF51621 157 340 2.09E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 SUPERFAMILY SSF51621 1 74 2.09E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 Gene3D G3DSA:3.20.20.60 168 322 1.4E-63 T 28-03-2018 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 Gene3D G3DSA:3.20.20.60 1 110 8.9E-19 T 28-03-2018 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 SUPERFAMILY SSF52935 324 472 5.76E-41 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 Pfam PF00224 Pyruvate kinase, barrel domain 1 343 4.9E-148 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS08445 1b0cebd3f610155120375aab6b63a504 474 Gene3D G3DSA:3.40.1380.20 323 472 1.5E-50 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CPF12_RS01010 d30f9a80962c381ff439450f47413381 196 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 189 33.572 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CPF12_RS01010 d30f9a80962c381ff439450f47413381 196 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 184 2.3E-44 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CPF12_RS01010 d30f9a80962c381ff439450f47413381 196 Gene3D G3DSA:3.20.20.70 1 189 3.7E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS01010 d30f9a80962c381ff439450f47413381 196 SUPERFAMILY SSF51366 2 187 8.48E-46 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS07790 6f232f5ca45b5f29b79fd1008fd8f88a 126 Pfam PF01597 Glycine cleavage H-protein 8 126 1.6E-42 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CPF12_RS07790 6f232f5ca45b5f29b79fd1008fd8f88a 126 Gene3D G3DSA:2.40.50.100 5 126 2.3E-44 T 28-03-2018 CPF12_RS07790 6f232f5ca45b5f29b79fd1008fd8f88a 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CPF12_RS07790 6f232f5ca45b5f29b79fd1008fd8f88a 126 SUPERFAMILY SSF51230 5 125 3.01E-42 T 28-03-2018 IPR011053 Single hybrid motif CPF12_RS07790 6f232f5ca45b5f29b79fd1008fd8f88a 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 5 125 1.6E-45 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CPF12_RS07790 6f232f5ca45b5f29b79fd1008fd8f88a 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 35.075 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Gene3D G3DSA:3.20.20.80 341 469 4.4E-21 T 28-03-2018 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Gene3D G3DSA:3.90.400.10 105 169 3.0E-25 T 28-03-2018 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 SUPERFAMILY SSF51445 4 473 4.23E-153 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 551 5.8E-245 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 SMART SM00642 13 415 1.5E-146 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Gene3D G3DSA:2.60.40.1180 470 553 5.3E-16 T 28-03-2018 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Pfam PF11941 Domain of unknown function (DUF3459) 459 550 2.8E-8 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 SUPERFAMILY SSF51011 476 551 3.66E-13 T 28-03-2018 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Gene3D G3DSA:3.20.20.470 170 340 1.8E-38 T 28-03-2018 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Gene3D G3DSA:3.20.20.470 1 104 5.7E-35 T 28-03-2018 CPF12_RS06860 178ba97d61123c7415aba49dc8a23837 556 Pfam PF00128 Alpha amylase, catalytic domain 28 373 2.4E-119 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS11380 20d59bf6326eb54774984b7cfc7ff121 97 Pfam PF09683 Bacteriocin (Lactococcin_972) 32 93 1.2E-13 T 28-03-2018 IPR006540 Bacteriocin, lactococcin 972 CPF12_RS11380 20d59bf6326eb54774984b7cfc7ff121 97 TIGRFAM TIGR01653 lactococcin_972: bacteriocin, lactococcin 972 family 6 96 7.1E-14 T 28-03-2018 IPR006540 Bacteriocin, lactococcin 972 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Gene3D G3DSA:3.40.1190.10 114 297 5.6E-36 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Pfam PF08245 Mur ligase middle domain 106 273 5.4E-25 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Gene3D G3DSA:3.40.1190.10 55 113 8.4E-6 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 33.136 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Gene3D G3DSA:3.90.190.20 298 432 7.9E-23 T 28-03-2018 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 SUPERFAMILY SSF51984 2 88 8.44E-18 T 28-03-2018 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 377 1.2E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 SUPERFAMILY SSF53623 87 292 3.01E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 Pfam PF01225 Mur ligase family, catalytic domain 3 101 9.9E-20 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 433 3.1E-120 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS09865 6c391c45804ac40ccfe6473ab568b702 435 SUPERFAMILY SSF53244 294 425 2.75E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 SUPERFAMILY SSF53955 66 277 3.94E-71 T 28-03-2018 IPR023346 Lysozyme-like domain CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 SUPERFAMILY SSF56601 285 626 1.17E-98 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 SUPERFAMILY SSF56601 233 255 1.17E-98 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 Gene3D G3DSA:1.10.3810.10 69 268 4.3E-74 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 Gene3D G3DSA:3.40.710.10 270 680 5.0E-95 T 28-03-2018 CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 Pfam PF00905 Penicillin binding protein transpeptidase domain 349 606 1.3E-35 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 88 613 2.6E-177 T 28-03-2018 CPF12_RS02895 5469b973bea6e5117be264fd55778337 699 Pfam PF00912 Transglycosylase 81 249 2.8E-61 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 Gene3D G3DSA:1.20.1560.10 3 346 1.3E-97 T 28-03-2018 CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 Pfam PF00664 ABC transporter transmembrane region 36 314 2.4E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 SUPERFAMILY SSF52540 354 598 7.83E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 SUPERFAMILY SSF90123 23 345 2.22E-88 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 SMART SM00382 387 573 2.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 Gene3D G3DSA:3.40.50.300 353 600 3.6E-74 T 28-03-2018 CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS03345 d1a5c31f71acd521ce99e23c63671487 602 Pfam PF00005 ABC transporter 379 527 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Gene3D G3DSA:1.10.1790.10 319 424 1.4E-9 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Gene3D G3DSA:3.40.50.2300 429 517 8.7E-11 T 28-03-2018 CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 SUPERFAMILY SSF63520 316 423 2.62E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Pfam PF00874 PRD domain 332 418 3.4E-9 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Pfam PF08279 HTH domain 28 83 4.6E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Gene3D G3DSA:1.10.10.10 21 88 6.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Gene3D G3DSA:1.10.10.10 111 174 2.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10810 ddc68adb5a0bf4f59a5101dcfbd91161 639 Pfam PF05043 Mga helix-turn-helix domain 120 185 1.1E-6 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 Gene3D G3DSA:1.10.287.130 194 263 1.2E-10 T 28-03-2018 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 418 1.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 SUPERFAMILY SSF55874 256 420 6.16E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 2.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 402 2.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 2.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 266 9.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 SUPERFAMILY SSF47384 193 268 1.94E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 SMART SM00388 200 267 6.9E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 SMART SM00387 312 423 4.4E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05000 5a283aae6804f149169234735765f4e1 423 Gene3D G3DSA:3.30.565.10 271 423 3.9E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08070 2f0a244922fb7692bf84e20fb076bdd7 240 SUPERFAMILY SSF100950 48 239 6.28E-38 T 28-03-2018 CPF12_RS08070 2f0a244922fb7692bf84e20fb076bdd7 240 Gene3D G3DSA:3.40.50.10420 46 239 1.1E-35 T 28-03-2018 CPF12_RS08070 2f0a244922fb7692bf84e20fb076bdd7 240 Pfam PF02589 LUD domain 56 238 5.9E-27 T 28-03-2018 IPR003741 LUD domain CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 Pfam PF04542 Sigma-70 region 2 15 79 4.0E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 Pfam PF08281 Sigma-70, region 4 106 158 3.8E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 Gene3D G3DSA:1.10.10.10 91 168 2.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 162 4.8E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 SUPERFAMILY SSF88946 9 83 2.0E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 Gene3D G3DSA:1.10.1740.10 7 82 3.1E-15 T 28-03-2018 CPF12_RS00570 027ed0aa37014cff07b2065563e6be61 168 SUPERFAMILY SSF88659 97 163 9.16E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 Gene3D G3DSA:4.10.640.10 2 79 1.2E-33 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 Pfam PF01084 Ribosomal protein S18 22 72 2.3E-27 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 76 8.6E-36 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.837 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 3.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 3.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 3.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 3.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 77 8.0E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05375 88271c00994255353224a15c883b2fb7 79 SUPERFAMILY SSF46911 4 77 9.68E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 804 0.0 T 28-03-2018 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Gene3D G3DSA:3.30.1360.40 237 333 1.1E-36 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 550 1.2E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 1.3E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 709 756 2.5E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 9.0E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 656 1.8E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 706 1.5E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 SMART SM00434 12 465 3.5E-281 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Gene3D G3DSA:1.10.268.10 345 487 3.1E-50 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 SUPERFAMILY SSF56719 32 487 1.14E-178 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 SUPERFAMILY SSF101904 500 818 1.23E-109 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Gene3D G3DSA:3.90.199.10 35 216 7.1E-85 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Gene3D G3DSA:2.120.10.90 498 808 6.7E-125 T 28-03-2018 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 3.1E-160 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS05535 55e5d734e7922849f68f026e4418bcad 842 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 6 808 24.661 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 SUPERFAMILY SSF54814 183 300 3.6E-42 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 282 3.7E-106 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 Gene3D G3DSA:3.40.50.300 6 56 4.3E-14 T 28-03-2018 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 Pfam PF01926 50S ribosome-binding GTPase 11 127 6.1E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 Gene3D G3DSA:3.40.50.300 57 179 4.9E-18 T 28-03-2018 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 78 96 2.1E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 2.1E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 Pfam PF07650 KH domain 210 288 1.4E-23 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 SUPERFAMILY SSF52540 11 206 5.23E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 171 9.0E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 Gene3D G3DSA:3.30.300.20 187 302 1.9E-45 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS09360 959b5a42a27d7050307156c0f36ee2f7 304 Hamap MF_00367 GTPase Era [era]. 6 299 37.618 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS03425 3a3378eb3905f346ab7d444ea83fdbd3 247 SUPERFAMILY SSF54909 3 246 3.75E-82 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CPF12_RS03425 3a3378eb3905f346ab7d444ea83fdbd3 247 Gene3D G3DSA:3.30.70.1100 138 243 7.5E-26 T 28-03-2018 CPF12_RS03425 3a3378eb3905f346ab7d444ea83fdbd3 247 Gene3D G3DSA:3.30.70.1030 4 135 7.6E-34 T 28-03-2018 CPF12_RS03425 3a3378eb3905f346ab7d444ea83fdbd3 247 Pfam PF06778 Chlorite dismutase 34 235 3.3E-67 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Gene3D G3DSA:3.40.50.300 2 138 5.2E-28 T 28-03-2018 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 46 65 2.9E-5 T 28-03-2018 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 306 325 2.9E-5 T 28-03-2018 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 128 1.6E-15 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 SUPERFAMILY SSF48019 238 424 2.44E-65 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Pfam PF16193 AAA C-terminal domain 174 252 1.4E-22 T 28-03-2018 IPR032423 AAA C-terminal domain CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 SMART SM00382 38 150 5.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 1.7E-59 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 SUPERFAMILY SSF52540 4 219 8.27E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Gene3D G3DSA:1.10.8.60 139 226 9.1E-17 T 28-03-2018 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Gene3D G3DSA:1.20.272.10 237 330 2.6E-33 T 28-03-2018 CPF12_RS09605 ef0b723f9875d01290b519733dce5fae 428 Gene3D G3DSA:1.10.3710.10 333 428 1.7E-25 T 28-03-2018 CPF12_RS05665 5cdd8816616a95d45a65563f31f17c72 109 Gene3D G3DSA:3.30.70.120 1 109 3.2E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CPF12_RS05665 5cdd8816616a95d45a65563f31f17c72 109 SUPERFAMILY SSF54913 1 108 3.48E-13 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CPF12_RS05665 5cdd8816616a95d45a65563f31f17c72 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 2.3E-51 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor CPF12_RS07810 ca5f158c6059bdc01ab5499fd098d903 271 Pfam PF03180 NLPA lipoprotein 32 269 3.3E-82 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS07810 ca5f158c6059bdc01ab5499fd098d903 271 SUPERFAMILY SSF53850 31 270 1.16E-75 T 28-03-2018 CPF12_RS07810 ca5f158c6059bdc01ab5499fd098d903 271 PIRSF PIRSF002854 1 271 2.4E-96 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS07810 ca5f158c6059bdc01ab5499fd098d903 271 Gene3D G3DSA:3.40.190.10 31 125 1.4E-29 T 28-03-2018 CPF12_RS07810 ca5f158c6059bdc01ab5499fd098d903 271 Gene3D G3DSA:3.40.190.10 126 270 4.2E-41 T 28-03-2018 CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.2E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.4E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.4E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.4E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 SUPERFAMILY SSF54999 6 102 2.88E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.303 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 SMART SM01403 7 101 1.5E-60 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 Gene3D G3DSA:3.30.70.600 3 102 3.2E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CPF12_RS06055 73bd995b485d8d6dea2a99b8f1440a77 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.3E-47 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS10845 6816e0e17e8394aeb59ae09e239a2005 369 Gene3D G3DSA:3.40.640.10 5 290 1.5E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS10845 6816e0e17e8394aeb59ae09e239a2005 369 Pfam PF03841 L-seryl-tRNA selenium transferase 105 269 4.3E-11 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CPF12_RS10845 6816e0e17e8394aeb59ae09e239a2005 369 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 9 367 4.8E-166 T 28-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 CPF12_RS10845 6816e0e17e8394aeb59ae09e239a2005 369 SUPERFAMILY SSF53383 13 368 7.42E-32 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS07060 30b8abaafa53a2090d5cd1538f89def9 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 320 2.6E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07060 30b8abaafa53a2090d5cd1538f89def9 400 SUPERFAMILY SSF51905 148 334 1.06E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07060 30b8abaafa53a2090d5cd1538f89def9 400 Gene3D G3DSA:3.50.50.60 145 358 3.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07060 30b8abaafa53a2090d5cd1538f89def9 400 Gene3D G3DSA:3.50.50.60 11 104 7.0E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07060 30b8abaafa53a2090d5cd1538f89def9 400 SUPERFAMILY SSF51905 3 204 1.2E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS01490 1abc0de58c7d8cd789ea74b1cb7e58ba 127 SUPERFAMILY SSF48013 3 123 3.14E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CPF12_RS01490 1abc0de58c7d8cd789ea74b1cb7e58ba 127 Pfam PF01029 NusB family 5 124 1.5E-32 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CPF12_RS01490 1abc0de58c7d8cd789ea74b1cb7e58ba 127 Gene3D G3DSA:1.10.940.10 1 127 1.1E-38 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CPF12_RS01490 1abc0de58c7d8cd789ea74b1cb7e58ba 127 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 127 20.726 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CPF12_RS01490 1abc0de58c7d8cd789ea74b1cb7e58ba 127 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 126 1.8E-39 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CPF12_RS08120 e4027ca7c2888c5b1c548a0b51f519f1 347 SUPERFAMILY SSF53474 76 345 1.98E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08120 e4027ca7c2888c5b1c548a0b51f519f1 347 Gene3D G3DSA:3.40.50.1820 43 347 2.9E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08120 e4027ca7c2888c5b1c548a0b51f519f1 347 Pfam PF07859 alpha/beta hydrolase fold 115 328 1.5E-60 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CPF12_RS08870 13f83a7c3dda536987770c5a0332e728 382 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 369 3.2E-87 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CPF12_RS08870 13f83a7c3dda536987770c5a0332e728 382 SUPERFAMILY SSF53383 3 372 8.25E-92 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS08870 13f83a7c3dda536987770c5a0332e728 382 PIRSF PIRSF000390 1 379 6.4E-97 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CPF12_RS08870 13f83a7c3dda536987770c5a0332e728 382 Gene3D G3DSA:3.40.640.10 2 242 6.2E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS08870 13f83a7c3dda536987770c5a0332e728 382 Gene3D G3DSA:3.90.1150.10 243 382 1.6E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 318 592 1.8E-56 T 28-03-2018 IPR003797 DegV CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 Pfam PF02645 Uncharacterised protein, DegV family COG1307 317 593 1.7E-50 T 28-03-2018 IPR003797 DegV CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 SUPERFAMILY SSF101473 6 202 9.55E-32 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 Gene3D G3DSA:3.40.50.10170 312 466 2.9E-36 T 28-03-2018 CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 SUPERFAMILY SSF82549 317 593 2.28E-56 T 28-03-2018 CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 Pfam PF02734 DAK2 domain 37 200 1.4E-31 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 SMART SM01120 37 201 7.9E-38 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 SMART SM01121 235 476 1.3E-4 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CPF12_RS00710 064699f11d36dc35e0dc7089d8a8d34b 603 Gene3D G3DSA:3.30.1180.10 467 600 5.0E-17 T 28-03-2018 CPF12_RS02660 43a09846fc30090ceea76d52f397da94 602 Pfam PF08439 Oligopeptidase F 115 184 1.3E-22 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CPF12_RS02660 43a09846fc30090ceea76d52f397da94 602 Pfam PF01432 Peptidase family M3 205 586 1.3E-76 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CPF12_RS02660 43a09846fc30090ceea76d52f397da94 602 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 8 597 1.8E-204 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CPF12_RS02660 43a09846fc30090ceea76d52f397da94 602 SUPERFAMILY SSF55486 56 599 3.01E-130 T 28-03-2018 CPF12_RS02660 43a09846fc30090ceea76d52f397da94 602 Gene3D G3DSA:1.10.1370.10 80 597 1.3E-38 T 28-03-2018 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 Gene3D G3DSA:3.40.190.10 31 154 1.6E-9 T 28-03-2018 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 133 150 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 SUPERFAMILY SSF53850 42 402 2.14E-75 T 28-03-2018 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 PRINTS PR00181 Maltose binding protein signature 240 259 1.8E-5 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 PRINTS PR00181 Maltose binding protein signature 365 384 1.8E-5 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 PRINTS PR00181 Maltose binding protein signature 130 149 1.8E-5 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 Gene3D G3DSA:3.40.190.10 155 413 9.0E-34 T 28-03-2018 CPF12_RS07740 6f57e6482e864eac6e1a17471876d63d 413 Pfam PF13416 Bacterial extracellular solute-binding protein 50 348 9.5E-41 T 28-03-2018 CPF12_RS02795 96317f81304ba3067818cfbfc73cd182 276 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 3.5E-22 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS02795 96317f81304ba3067818cfbfc73cd182 276 SUPERFAMILY SSF56784 1 267 1.47E-64 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02795 96317f81304ba3067818cfbfc73cd182 276 Gene3D G3DSA:3.40.50.1000 1 273 3.9E-37 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02795 96317f81304ba3067818cfbfc73cd182 276 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 4.7E-60 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS02795 96317f81304ba3067818cfbfc73cd182 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 7.4E-62 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02795 96317f81304ba3067818cfbfc73cd182 276 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 28-03-2018 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Pfam PF14480 DNA polymerase III polC-type N-terminus I 9 81 1.1E-10 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 828 1236 1.5E-91 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 SUPERFAMILY SSF50249 239 323 9.08E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 209 3.2E-11 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Gene3D G3DSA:3.20.20.140 336 767 8.9E-60 T 28-03-2018 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 415 635 8.7E-53 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 SUPERFAMILY SSF53098 422 877 2.02E-100 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1439 425.615 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 234 1439 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Pfam PF02811 PHP domain 338 697 6.2E-47 T 28-03-2018 IPR004013 PHP domain GO:0003824 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 SMART SM00479 422 588 3.0E-50 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 SMART SM00481 337 404 2.0E-25 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Pfam PF14579 Helix-hairpin-helix motif 1352 1431 1.3E-6 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Gene3D G3DSA:2.40.50.140 223 324 1.2E-19 T 28-03-2018 CPF12_RS12225 a6bc6bd364d58f5524e095c256f67119 1439 Pfam PF00929 Exonuclease 424 578 7.3E-38 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 SUPERFAMILY SSF88723 2 147 1.41E-42 T 28-03-2018 IPR029060 PIN domain-like CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 SMART SM00475 1 255 1.3E-100 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 Gene3D G3DSA:3.40.50.1010 1 178 1.2E-56 T 28-03-2018 IPR029060 PIN domain-like CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 SMART SM00279 167 202 5.8E-14 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 162 9.4E-44 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 165 255 2.2E-25 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 SUPERFAMILY SSF47807 165 260 1.48E-24 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CPF12_RS10515 669fc441d175311a4169244076ee0ce5 282 Gene3D G3DSA:1.10.150.20 179 256 4.2E-23 T 28-03-2018 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 SUPERFAMILY SSF48150 10 227 6.75E-77 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Pfam PF14815 NUDIX domain 241 350 2.3E-20 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 197 213 2.3E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 11 280 2.1E-108 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Pfam PF00633 Helix-hairpin-helix motif 105 133 2.2E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Gene3D G3DSA:3.90.79.10 234 359 5.8E-14 T 28-03-2018 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 SMART SM00478 44 195 4.6E-48 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 SMART SM00525 196 216 1.8E-6 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 40 173 1.7E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 SUPERFAMILY SSF55811 225 353 4.06E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Gene3D G3DSA:1.10.340.30 26 122 1.1E-29 T 28-03-2018 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 197 213 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CPF12_RS09975 fd9432d10a3774435623c01980a9e313 359 Gene3D G3DSA:1.10.1670.10 123 230 6.9E-42 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CPF12_RS02130 658647a0b321c3056bec889399c5399d 73 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 7 59 1.8E-18 T 28-03-2018 IPR019241 Protein of unknown function DUF2197 CPF12_RS12440 d01c6e4989ed35cb8fffca726efcae0d 110 Pfam PF01476 LysM domain 44 94 2.4E-4 T 28-03-2018 IPR018392 LysM domain CPF12_RS12440 d01c6e4989ed35cb8fffca726efcae0d 110 Gene3D G3DSA:3.10.350.10 37 100 1.4E-11 T 28-03-2018 CPF12_RS12440 d01c6e4989ed35cb8fffca726efcae0d 110 SUPERFAMILY SSF54106 43 95 6.67E-5 T 28-03-2018 IPR018392 LysM domain CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 43 57 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 10 93 26.754 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 Gene3D G3DSA:2.40.50.100 29 93 1.8E-27 T 28-03-2018 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 37 78 1.0E-15 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 PRINTS PR00063 Ribosomal protein L27 signature 13 37 7.6E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 PRINTS PR00063 Ribosomal protein L27 signature 63 87 7.6E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 PRINTS PR00063 Ribosomal protein L27 signature 38 62 7.6E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 10 90 5.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 Pfam PF01016 Ribosomal L27 protein 11 90 4.2E-34 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01060 f64ce0b724ff37869501a450617d7f3f 97 SUPERFAMILY SSF110324 11 92 3.0E-31 T 28-03-2018 CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 SMART SM00471 504 659 1.1E-9 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 TIGRFAM TIGR00277 HDIG: HDIG domain 505 603 6.4E-25 T 28-03-2018 IPR006675 HDIG domain CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 Pfam PF07698 7TM receptor with intracellular HD hydrolase 284 483 7.2E-21 T 28-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 Pfam PF01966 HD domain 508 649 1.1E-16 T 28-03-2018 IPR006674 HD domain CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 SUPERFAMILY SSF109604 497 683 3.14E-16 T 28-03-2018 CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 Pfam PF07697 7TM-HD extracellular 48 277 1.4E-34 T 28-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain CPF12_RS09340 0ff9874567cf1385a832c08f6ec806b9 712 Gene3D G3DSA:1.10.3210.10 459 693 9.3E-30 T 28-03-2018 CPF12_RS07700 06c7045e80923555cd4b094cba94c21f 320 SUPERFAMILY SSF111331 12 318 2.4E-64 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CPF12_RS07700 06c7045e80923555cd4b094cba94c21f 320 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 13 312 1.0E-39 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CPF12_RS07700 06c7045e80923555cd4b094cba94c21f 320 Gene3D G3DSA:3.40.50.10330 5 153 4.6E-27 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CPF12_RS07700 06c7045e80923555cd4b094cba94c21f 320 Pfam PF00781 Diacylglycerol kinase catalytic domain 12 129 5.0E-24 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CPF12_RS07700 06c7045e80923555cd4b094cba94c21f 320 SMART SM00046 11 135 0.0088 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 SMART SM00650 38 213 2.2E-76 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 54 81 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 22 289 53.99 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 23 287 3.0E-80 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 Gene3D G3DSA:3.40.50.150 6 227 2.6E-54 T 28-03-2018 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 SUPERFAMILY SSF53335 19 292 1.39E-68 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 Gene3D G3DSA:1.10.8.100 228 290 3.7E-21 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CPF12_RS05725 8c1d341df63cac4f6ac7cc98bcb02baa 297 Pfam PF00398 Ribosomal RNA adenine dimethylase 23 288 1.3E-61 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 2.5E-46 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 8 311 42.901 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 Gene3D G3DSA:3.40.50.2020 8 145 1.8E-57 T 28-03-2018 CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 Gene3D G3DSA:3.40.50.2020 146 311 2.3E-36 T 28-03-2018 CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 9 310 2.5E-103 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 SUPERFAMILY SSF53271 6 161 1.61E-52 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 SUPERFAMILY SSF53271 91 307 2.96E-41 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 310 3.4E-22 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS06685 cf3a624e67efca07d5f63a0df1c2271e 311 SMART SM01400 8 124 6.2E-71 T 28-03-2018 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 SUPERFAMILY SSF47323 339 471 1.53E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 471 6.5E-184 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 Pfam PF09190 DALR domain 355 411 1.3E-13 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 Gene3D G3DSA:1.20.120.640 307 408 2.5E-17 T 28-03-2018 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 472 38.869 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 SMART SM00840 354 421 2.8E-11 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 Gene3D G3DSA:3.40.50.620 1 305 4.5E-93 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 1.8E-133 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 SUPERFAMILY SSF52374 4 312 6.7E-100 T 28-03-2018 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CPF12_RS05955 b571370c0e1dfb394e9ea4dd39a4800a 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.4E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CPF12_RS05325 fe249ef2f44a046b86faa0ce292b395a 185 Gene3D G3DSA:3.90.70.10 6 185 4.0E-24 T 28-03-2018 CPF12_RS05325 fe249ef2f44a046b86faa0ce292b395a 185 PIRSF PIRSF032442 1 183 9.2E-70 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CPF12_RS05325 fe249ef2f44a046b86faa0ce292b395a 185 Pfam PF13529 Peptidase_C39 like family 5 155 1.1E-34 T 28-03-2018 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 Gene3D G3DSA:3.40.47.10 1 160 5.1E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 310 69.241 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 310 1.0E-127 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 SUPERFAMILY SSF53901 3 310 1.81E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 310 2.1E-38 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 1.1E-30 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CPF12_RS02725 2f1d9d1ede71f177bdc0cef6910b60c1 312 Gene3D G3DSA:3.40.47.10 161 310 3.4E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 SUPERFAMILY SSF50249 4 108 1.24E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 SUPERFAMILY SSF55681 113 297 3.78E-108 T 28-03-2018 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 SUPERFAMILY SSF55681 426 586 3.78E-108 T 28-03-2018 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 Gene3D G3DSA:3.30.930.10 136 588 3.4E-108 T 28-03-2018 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 1.7E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 3.4E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 3.4E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 3.4E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 3.4E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 SUPERFAMILY SSF55261 294 421 1.34E-40 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 Gene3D G3DSA:2.40.50.140 1 111 2.1E-28 T 28-03-2018 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 559 3.1E-107 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 585 8.1E-250 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 34.471 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CPF12_RS01775 338c3a875a2d9fdd54bb86ef3e93d3ce 590 Pfam PF02938 GAD domain 313 407 8.3E-28 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CPF12_RS03600 a7e85d79f677d42c7dbd92e157503a5a 381 PIRSF PIRSF001434 1 381 1.7E-138 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS03600 a7e85d79f677d42c7dbd92e157503a5a 381 Gene3D G3DSA:3.40.640.10 3 247 5.5E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS03600 a7e85d79f677d42c7dbd92e157503a5a 381 Gene3D G3DSA:3.90.1150.10 249 381 4.0E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS03600 a7e85d79f677d42c7dbd92e157503a5a 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 378 8.0E-142 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS03600 a7e85d79f677d42c7dbd92e157503a5a 381 SUPERFAMILY SSF53383 13 379 2.92E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS03600 a7e85d79f677d42c7dbd92e157503a5a 381 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 393 1.2E-143 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 Pfam PF02441 Flavoprotein 4 174 1.7E-49 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 SUPERFAMILY SSF52507 3 176 2.62E-61 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 Gene3D G3DSA:3.40.50.10300 182 396 1.2E-64 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 184 368 9.2E-69 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 SUPERFAMILY SSF102645 182 394 7.98E-72 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CPF12_RS11445 94d511863ce7a531d6481e1eec58f981 401 Gene3D G3DSA:3.40.50.1950 1 181 7.8E-58 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CPF12_RS05810 c78135ba073bade14164cbd0cd398127 179 Gene3D G3DSA:3.40.50.2020 1 179 1.8E-47 T 28-03-2018 CPF12_RS05810 c78135ba073bade14164cbd0cd398127 179 SUPERFAMILY SSF53271 4 177 9.96E-59 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS05810 c78135ba073bade14164cbd0cd398127 179 Pfam PF00156 Phosphoribosyl transferase domain 13 159 9.7E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CPF12_RS05810 c78135ba073bade14164cbd0cd398127 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 1.8E-66 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CPF12_RS09380 12da10ef5b668a965f3893c60a295582 147 Gene3D G3DSA:1.10.10.10 8 97 1.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09380 12da10ef5b668a965f3893c60a295582 147 Pfam PF01475 Ferric uptake regulator family 16 136 2.7E-38 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CPF12_RS09380 12da10ef5b668a965f3893c60a295582 147 SUPERFAMILY SSF46785 7 141 3.56E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 PIRSF PIRSF000161 3 267 3.8E-71 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 267 1.2E-80 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 SUPERFAMILY SSF55347 130 238 6.32E-39 T 28-03-2018 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 Gene3D G3DSA:3.30.360.10 131 235 3.4E-36 T 28-03-2018 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 SUPERFAMILY SSF51735 3 155 2.89E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 267 29.613 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 266 1.5E-31 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 Gene3D G3DSA:3.40.50.720 1 125 1.0E-30 T 28-03-2018 CPF12_RS10285 3df3c96bd9b3e6671248c45f0175956b 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 129 4.0E-33 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS04085 6449037a67eab72e0440c3f453f2ef44 198 Pfam PF03413 Peptidase propeptide and YPEB domain 55 112 2.1E-7 T 28-03-2018 IPR025711 PepSY domain CPF12_RS04085 6449037a67eab72e0440c3f453f2ef44 198 Pfam PF03413 Peptidase propeptide and YPEB domain 139 196 1.4E-5 T 28-03-2018 IPR025711 PepSY domain CPF12_RS04085 6449037a67eab72e0440c3f453f2ef44 198 Gene3D G3DSA:3.10.450.40 138 196 6.5E-13 T 28-03-2018 CPF12_RS04085 6449037a67eab72e0440c3f453f2ef44 198 Gene3D G3DSA:3.10.450.40 55 115 5.3E-10 T 28-03-2018 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SUPERFAMILY SSF52540 712 884 7.45E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SUPERFAMILY SSF52540 280 329 7.45E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SUPERFAMILY SSF52540 414 484 7.45E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SUPERFAMILY SSF52540 665 679 7.45E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 170 7.5E-25 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 Pfam PF13307 Helicase C-terminal domain 739 902 3.9E-40 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 6 921 3.2E-229 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 Gene3D G3DSA:3.30.420.10 3 184 2.6E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 Gene3D G3DSA:3.40.50.300 258 696 2.1E-29 T 28-03-2018 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 Pfam PF00929 Exonuclease 8 164 1.2E-30 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SUPERFAMILY SSF53098 6 207 4.29E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SMART SM00487 257 584 4.8E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SMART SM00479 6 173 1.2E-41 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 SMART SM00491 756 890 9.6E-33 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 Pfam PF04851 Type III restriction enzyme, res subunit 259 475 1.7E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CPF12_RS10325 c0b2f588dabc467cce379c7fd523fd21 930 Gene3D G3DSA:3.40.50.300 720 899 4.2E-11 T 28-03-2018 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Gene3D G3DSA:1.10.1790.10 303 411 1.4E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Gene3D G3DSA:1.10.1790.10 182 302 2.5E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 SUPERFAMILY SSF46785 93 156 1.86E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Gene3D G3DSA:1.10.10.10 90 160 9.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Gene3D G3DSA:1.10.10.10 4 71 1.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 SUPERFAMILY SSF55804 512 651 5.89E-22 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Gene3D G3DSA:3.40.930.10 513 653 3.1E-24 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Gene3D G3DSA:3.40.50.2300 415 501 5.6E-14 T 28-03-2018 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 515 651 1.1E-19 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 SUPERFAMILY SSF63520 311 410 8.76E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Pfam PF00874 PRD domain 213 299 2.4E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Pfam PF00874 PRD domain 330 406 3.0E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Pfam PF08279 HTH domain 97 152 1.2E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 Pfam PF05043 Mga helix-turn-helix domain 10 80 1.1E-5 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 SUPERFAMILY SSF52794 420 495 3.82E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS00380 63fd4ce099f01ca866ad65e2729f14a9 657 SUPERFAMILY SSF63520 204 300 2.62E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 Pfam PF01168 Alanine racemase, N-terminal domain 13 230 3.3E-58 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 Gene3D G3DSA:2.40.37.10 230 371 7.9E-51 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 Pfam PF00842 Alanine racemase, C-terminal domain 246 370 5.9E-39 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 SUPERFAMILY SSF50621 240 371 2.16E-46 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 Hamap MF_01201 Alanine racemase. 6 371 32.933 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 TIGRFAM TIGR00492 alr: alanine racemase 7 371 7.7E-111 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 SUPERFAMILY SSF51419 13 246 4.25E-58 T 28-03-2018 IPR029066 PLP-binding barrel CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 279 294 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 68 86 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 203 230 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 163 174 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 299 316 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 353 366 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 32 48 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 PRINTS PR00992 Alanine racemase signature 128 140 1.9E-62 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 Gene3D G3DSA:3.20.20.10 1 229 1.1E-39 T 28-03-2018 IPR029066 PLP-binding barrel CPF12_RS09030 162b8e0944832b6ae76619be80826c44 371 SMART SM01005 245 371 1.0E-59 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS06210 a8842606ebbaa214c4b3528d83c9306a 265 Pfam PF02361 Cobalt transport protein 13 236 5.2E-58 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CPF12_RS06210 a8842606ebbaa214c4b3528d83c9306a 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 37.361 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 Pfam PF01259 SAICAR synthetase 7 232 5.5E-64 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 SUPERFAMILY SSF56104 2 236 7.19E-79 T 28-03-2018 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 7 234 1.0E-71 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 30.829 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 Gene3D G3DSA:3.30.470.20 94 221 2.8E-48 T 28-03-2018 CPF12_RS08685 fc7eb1a55d167a73f931de100e55fd33 240 Gene3D G3DSA:3.30.200.20 1 93 1.1E-26 T 28-03-2018 CPF12_RS09645 28f4fc6742c57a9fea7dc377266196f4 144 Gene3D G3DSA:1.10.10.10 1 142 2.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09645 28f4fc6742c57a9fea7dc377266196f4 144 SMART SM00347 24 124 3.6E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS09645 28f4fc6742c57a9fea7dc377266196f4 144 Pfam PF01047 MarR family 31 89 1.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS09645 28f4fc6742c57a9fea7dc377266196f4 144 SUPERFAMILY SSF46785 3 136 1.01E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 SUPERFAMILY SSF56300 178 238 1.36E-9 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 SUPERFAMILY SSF56300 273 280 1.36E-9 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 SUPERFAMILY SSF56300 388 487 1.36E-9 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 SUPERFAMILY SSF56300 523 574 1.36E-9 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 Gene3D G3DSA:3.60.21.10 20 136 2.0E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 Gene3D G3DSA:3.60.21.10 143 592 7.7E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 PIRSF PIRSF000906 1 650 0.0 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 7 647 3.0E-292 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CPF12_RS03690 50b244085cab9c848c91e6f4030654b0 656 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 5 649 38.726 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CPF12_RS09650 f87b84e9c731a63a509c0418450a9088 218 SUPERFAMILY SSF55469 6 207 5.89E-51 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CPF12_RS09650 f87b84e9c731a63a509c0418450a9088 218 Gene3D G3DSA:3.40.109.10 1 209 2.1E-43 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CPF12_RS09650 f87b84e9c731a63a509c0418450a9088 218 Pfam PF00881 Nitroreductase family 11 189 6.5E-28 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CPF12_RS11625 2a7c47af266208e05f8c3f7b7ead1d70 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 24.928 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11625 2a7c47af266208e05f8c3f7b7ead1d70 90 Pfam PF00886 Ribosomal protein S16 9 67 2.0E-25 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11625 2a7c47af266208e05f8c3f7b7ead1d70 90 Gene3D G3DSA:3.30.1320.10 2 85 1.9E-34 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11625 2a7c47af266208e05f8c3f7b7ead1d70 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.2E-34 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11625 2a7c47af266208e05f8c3f7b7ead1d70 90 SUPERFAMILY SSF54565 2 87 1.83E-34 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS12375 1f2782cc75208cf912e77688f5933ecf 383 Gene3D G3DSA:3.60.21.10 72 272 1.3E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS12375 1f2782cc75208cf912e77688f5933ecf 383 Gene3D G3DSA:3.60.21.10 1 71 4.8E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS12375 1f2782cc75208cf912e77688f5933ecf 383 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 248 1.0E-52 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CPF12_RS12375 1f2782cc75208cf912e77688f5933ecf 383 Pfam PF00149 Calcineurin-like phosphoesterase 1 181 1.6E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CPF12_RS12375 1f2782cc75208cf912e77688f5933ecf 383 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 270 358 6.5E-10 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CPF12_RS12375 1f2782cc75208cf912e77688f5933ecf 383 SUPERFAMILY SSF56300 1 283 6.99E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS03930 b8ec79d8632c53dfef470d4755671500 437 Pfam PF13520 Amino acid permease 10 410 2.8E-58 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CPF12_RS03930 b8ec79d8632c53dfef470d4755671500 437 PIRSF PIRSF006060 1 437 4.5E-85 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CPF12_RS06195 6f9cb319e9b4d24599f5367d04981e23 136 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 135 25.959 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06195 6f9cb319e9b4d24599f5367d04981e23 136 SUPERFAMILY SSF64263 2 135 1.11E-37 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06195 6f9cb319e9b4d24599f5367d04981e23 136 Gene3D G3DSA:3.90.1030.10 1 136 3.8E-43 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06195 6f9cb319e9b4d24599f5367d04981e23 136 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 135 4.4E-41 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06195 6f9cb319e9b4d24599f5367d04981e23 136 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06195 6f9cb319e9b4d24599f5367d04981e23 136 Pfam PF01196 Ribosomal protein L17 16 135 5.3E-35 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS00235 f33905f5bf0b97a51ad5def8ae2acee3 187 Pfam PF01923 Cobalamin adenosyltransferase 4 165 1.5E-52 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CPF12_RS00235 f33905f5bf0b97a51ad5def8ae2acee3 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 7.2E-63 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CPF12_RS00235 f33905f5bf0b97a51ad5def8ae2acee3 187 Gene3D G3DSA:1.20.1200.10 12 185 1.2E-55 T 28-03-2018 CPF12_RS00235 f33905f5bf0b97a51ad5def8ae2acee3 187 SUPERFAMILY SSF89028 1 178 4.9E-58 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CPF12_RS00235 f33905f5bf0b97a51ad5def8ae2acee3 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 177 5.0E-52 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 493 1.0E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Gene3D G3DSA:3.40.50.980 152 305 2.6E-34 T 28-03-2018 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Gene3D G3DSA:3.40.50.980 2 151 1.5E-29 T 28-03-2018 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 505 228.713 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Gene3D G3DSA:3.30.300.30 399 505 7.9E-25 T 28-03-2018 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 505 6.1E-217 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 28-03-2018 IPR020845 AMP-binding, conserved site CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 SUPERFAMILY SSF56801 5 502 1.13E-116 T 28-03-2018 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 430 5.7E-106 T 28-03-2018 IPR010071 Amino acid adenylation domain CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Pfam PF00501 AMP-binding enzyme 13 405 9.3E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CPF12_RS07390 2d995f4277b3c10c0f306e1814440dd4 505 Gene3D G3DSA:2.30.38.10 306 398 2.5E-19 T 28-03-2018 CPF12_RS00940 3fa99c2516def0d05f69d749daf29a5e 205 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 52 178 7.5E-41 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CPF12_RS00940 3fa99c2516def0d05f69d749daf29a5e 205 Gene3D G3DSA:3.30.1380.10 15 191 9.5E-36 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CPF12_RS00940 3fa99c2516def0d05f69d749daf29a5e 205 SUPERFAMILY SSF55166 37 187 1.73E-36 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CPF12_RS06555 e084fe8096d49dbe1c06f9a6509dd923 221 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 21 220 1.1E-64 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CPF12_RS06555 e084fe8096d49dbe1c06f9a6509dd923 221 SUPERFAMILY SSF52540 39 215 1.88E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06555 e084fe8096d49dbe1c06f9a6509dd923 221 Pfam PF13614 AAA domain 50 203 7.6E-16 T 28-03-2018 IPR025669 AAA domain CPF12_RS06555 e084fe8096d49dbe1c06f9a6509dd923 221 Gene3D G3DSA:3.40.50.300 5 219 1.8E-35 T 28-03-2018 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 Gene3D G3DSA:1.10.1060.10 282 400 7.3E-13 T 28-03-2018 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 Pfam PF11870 Domain of unknown function (DUF3390) 386 484 2.7E-6 T 28-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 SUPERFAMILY SSF46548 275 391 2.79E-17 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 Pfam PF02589 LUD domain 70 295 7.2E-49 T 28-03-2018 IPR003741 LUD domain CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 19 465 1.9E-168 T 28-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 SUPERFAMILY SSF100950 136 296 1.21E-33 T 28-03-2018 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 SUPERFAMILY SSF100950 64 89 1.21E-33 T 28-03-2018 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 Gene3D G3DSA:3.40.50.10420 63 137 2.0E-8 T 28-03-2018 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 Gene3D G3DSA:3.40.50.10420 138 281 1.0E-39 T 28-03-2018 CPF12_RS08065 117c9878e160088ceb0f863ab136c96d 494 Pfam PF13183 4Fe-4S dicluster domain 311 377 6.4E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CPF12_RS04120 67632e73e9e4a4bfcda04f574c1971fd 362 Gene3D G3DSA:2.40.100.10 244 358 1.3E-36 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS04120 67632e73e9e4a4bfcda04f574c1971fd 362 SUPERFAMILY SSF50891 247 358 4.93E-35 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS04120 67632e73e9e4a4bfcda04f574c1971fd 362 Gene3D G3DSA:3.20.20.70 3 238 9.3E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS04120 67632e73e9e4a4bfcda04f574c1971fd 362 SUPERFAMILY SSF51445 1 242 2.32E-80 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS04120 67632e73e9e4a4bfcda04f574c1971fd 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 358 6.7E-128 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 389 3.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 SMART SM00388 166 233 1.6E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 SMART SM00387 274 390 1.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 Gene3D G3DSA:3.30.565.10 234 392 4.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 SUPERFAMILY SSF55874 230 388 1.44E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 325 1.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 366 1.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 SMART SM00304 112 165 8.5E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 230 1.9E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 Gene3D G3DSA:1.10.287.130 156 229 4.0E-10 T 28-03-2018 CPF12_RS11915 a8a3d42d066b40e5dde4c5cc6bec1a7d 392 SUPERFAMILY SSF47384 149 228 6.87E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 SUPERFAMILY SSF52540 323 569 1.36E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 Gene3D G3DSA:1.20.1560.10 2 316 1.6E-64 T 28-03-2018 CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 Gene3D G3DSA:3.40.50.300 317 571 7.3E-77 T 28-03-2018 CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 SMART SM00382 358 544 5.8E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 Pfam PF00664 ABC transporter transmembrane region 17 286 2.0E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 Pfam PF00005 ABC transporter 349 498 2.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00420 4c14f8e00a6746091e8bb9191ae8d7b4 571 SUPERFAMILY SSF90123 3 319 3.14E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS04010 588836e7a6f06d73bcbf475b1b1bfe38 271 Pfam PF03609 PTS system sorbose-specific iic component 6 237 1.5E-75 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CPF12_RS04010 588836e7a6f06d73bcbf475b1b1bfe38 271 Gene3D G3DSA:3.40.50.720 80 210 9.0E-4 T 28-03-2018 CPF12_RS04010 588836e7a6f06d73bcbf475b1b1bfe38 271 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 270 2.3E-111 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CPF12_RS09940 ca163cc0f75fad013fb28f6d981ac822 166 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 95 6.4E-25 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS09940 ca163cc0f75fad013fb28f6d981ac822 166 Gene3D G3DSA:1.10.10.10 1 146 9.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09940 ca163cc0f75fad013fb28f6d981ac822 166 SUPERFAMILY SSF46785 2 94 2.26E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09940 ca163cc0f75fad013fb28f6d981ac822 166 Pfam PF02082 Transcriptional regulator 1 83 5.9E-23 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS09940 ca163cc0f75fad013fb28f6d981ac822 166 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 Gene3D G3DSA:3.40.50.300 82 188 9.6E-33 T 28-03-2018 CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 36.455 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 1.5E-73 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 Gene3D G3DSA:3.40.50.300 1 51 1.0E-8 T 28-03-2018 CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 SMART SM00072 4 187 2.1E-66 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 SUPERFAMILY SSF52540 4 193 7.81E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 Gene3D G3DSA:3.30.63.10 52 81 1.8E-22 T 28-03-2018 CPF12_RS11435 9dab73fe0735dea5dc432de3b1a82efa 206 Pfam PF00625 Guanylate kinase 7 184 2.6E-51 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CPF12_RS06990 70b53f2c484a4b06c3328051e24aec26 444 PIRSF PIRSF006603 4 444 8.9E-75 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS06990 70b53f2c484a4b06c3328051e24aec26 444 Pfam PF01554 MatE 241 402 5.5E-29 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS06990 70b53f2c484a4b06c3328051e24aec26 444 Pfam PF01554 MatE 16 176 6.6E-26 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS06990 70b53f2c484a4b06c3328051e24aec26 444 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 415 6.3E-63 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS03775 3e4a50e3c5f1877856de162d0f98d5b4 289 Pfam PF09323 Domain of unknown function (DUF1980) 1 191 9.2E-54 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CPF12_RS03775 3e4a50e3c5f1877856de162d0f98d5b4 289 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 283 2.3E-54 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CPF12_RS02970 bf51beac1491b618b29bdaffbbb7db9a 241 SMART SM00382 26 214 2.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02970 bf51beac1491b618b29bdaffbbb7db9a 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02970 bf51beac1491b618b29bdaffbbb7db9a 241 Pfam PF00005 ABC transporter 17 166 3.5E-39 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02970 bf51beac1491b618b29bdaffbbb7db9a 241 Gene3D G3DSA:3.40.50.300 1 240 9.8E-77 T 28-03-2018 CPF12_RS02970 bf51beac1491b618b29bdaffbbb7db9a 241 SUPERFAMILY SSF52540 1 235 3.84E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02970 bf51beac1491b618b29bdaffbbb7db9a 241 PIRSF PIRSF039085 1 241 2.5E-111 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 Gene3D G3DSA:3.40.50.300 73 284 1.3E-45 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 SUPERFAMILY SSF52540 73 293 9.47E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 454 1.4E-200 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 SMART SM00382 92 246 3.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 Hamap MF_01498 DNA repair protein RadA [radA]. 23 458 43.329 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 Pfam PF13541 Subunit ChlI of Mg-chelatase 366 432 1.8E-9 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 SUPERFAMILY SSF54211 305 458 7.59E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 SUPERFAMILY SSF54211 257 271 7.59E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 250 276 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 126 143 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 176 200 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 324 347 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 12 36 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 84 112 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 PRINTS PR01874 DNA repair protein radA signature 215 243 6.5E-91 T 28-03-2018 CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 Gene3D G3DSA:3.30.230.10 285 459 8.5E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05925 3af21afac83bb200aedfd4d880a6d284 461 Pfam PF13481 AAA domain 66 224 7.2E-19 T 28-03-2018 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 Pfam PF13840 ACT domain 336 396 1.5E-13 T 28-03-2018 IPR027795 GATS-like ACT domain CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 4 401 2.2E-132 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 SUPERFAMILY SSF55021 250 347 2.12E-10 T 28-03-2018 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 Pfam PF00696 Amino acid kinase family 3 228 7.5E-51 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 Gene3D G3DSA:3.40.1160.10 1 238 1.8E-67 T 28-03-2018 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 Gene3D G3DSA:3.30.70.260 239 331 8.3E-14 T 28-03-2018 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 SUPERFAMILY SSF55021 330 402 3.82E-20 T 28-03-2018 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 SUPERFAMILY SSF53633 4 241 7.46E-70 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 401 1.3E-111 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 PIRSF PIRSF000726 58 403 4.6E-114 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 PIRSF PIRSF000726 1 62 3.5E-18 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS02300 a7bca04b5b99f9186697105bd99d4767 403 Gene3D G3DSA:3.30.70.260 332 402 2.6E-18 T 28-03-2018 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 141 224 4.9E-40 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 SUPERFAMILY SSF51735 2 145 3.19E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 SUPERFAMILY SSF55347 121 259 1.05E-59 T 28-03-2018 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 Pfam PF13288 DXP reductoisomerase C-terminal domain 256 373 4.4E-42 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 375 8.7E-154 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 3 378 45.409 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 SUPERFAMILY SSF69055 287 378 5.1E-30 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 PIRSF PIRSF006205 1 379 1.1E-155 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 127 4.2E-38 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 Gene3D G3DSA:3.40.50.720 1 145 1.1E-44 T 28-03-2018 CPF12_RS12315 d4c9d733c86e4c8345eed0cc4db93938 379 Gene3D G3DSA:1.10.1740.10 299 379 2.6E-28 T 28-03-2018 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 Gene3D G3DSA:3.30.70.260 332 403 9.3E-7 T 28-03-2018 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 Gene3D G3DSA:3.40.1160.10 1 240 5.4E-59 T 28-03-2018 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 SUPERFAMILY SSF55021 265 346 1.3E-5 T 28-03-2018 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 Gene3D G3DSA:3.30.70.260 241 331 7.5E-9 T 28-03-2018 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 Pfam PF13840 ACT domain 335 398 2.2E-6 T 28-03-2018 IPR027795 GATS-like ACT domain CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 SUPERFAMILY SSF53633 4 247 5.76E-65 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 PIRSF PIRSF000726 60 403 6.7E-81 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 PIRSF PIRSF000726 1 65 2.1E-8 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 SUPERFAMILY SSF55021 339 400 1.68E-8 T 28-03-2018 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 68 400 2.0E-81 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CPF12_RS12125 4dd86f7ace0e66c7a3c1db7ffa2a68d4 404 Pfam PF00696 Amino acid kinase family 2 236 5.4E-46 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS10220 536b2d272db06a0116369312f81d8f96 491 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 127 481 2.0E-102 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CPF12_RS10220 536b2d272db06a0116369312f81d8f96 491 SUPERFAMILY SSF56322 64 482 3.27E-92 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CPF12_RS10220 536b2d272db06a0116369312f81d8f96 491 Gene3D G3DSA:3.60.120.10 20 484 4.7E-94 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CPF12_RS10220 536b2d272db06a0116369312f81d8f96 491 Pfam PF00425 chorismate binding enzyme 221 473 4.5E-70 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 6.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 6.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 Gene3D G3DSA:3.40.640.10 157 364 6.3E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 SUPERFAMILY SSF53383 93 473 1.67E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 Gene3D G3DSA:1.10.10.10 2 77 7.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 Gene3D G3DSA:3.90.1150.10 365 474 2.6E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.7E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 Pfam PF00155 Aminotransferase class I and II 161 462 1.3E-29 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 SUPERFAMILY SSF46785 7 84 4.34E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12005 d7b4b0ca26de00f205442685bcdbc1e1 474 SMART SM00345 16 75 6.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 6 439 47.079 T 28-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 Gene3D G3DSA:3.40.50.300 222 447 4.9E-41 T 28-03-2018 CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 SMART SM00490 260 341 3.9E-30 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 SMART SM00487 25 224 3.0E-47 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 SUPERFAMILY SSF52540 74 363 7.86E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 Pfam PF00271 Helicase conserved C-terminal domain 237 341 1.2E-27 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 Gene3D G3DSA:3.40.50.300 13 221 6.4E-48 T 28-03-2018 CPF12_RS10385 d9efff1f8c761d59b9df5e2b58479d8d 447 Pfam PF00270 DEAD/DEAH box helicase 30 196 2.1E-40 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 SUPERFAMILY SSF53686 9 360 1.57E-98 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 Gene3D G3DSA:3.40.50.1100 141 318 9.4E-45 T 28-03-2018 CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 323 415 8.6E-22 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 SUPERFAMILY SSF55021 333 411 1.69E-9 T 28-03-2018 CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 Gene3D G3DSA:3.40.50.1100 32 140 6.1E-31 T 28-03-2018 CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 310 5.4E-80 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 45 58 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CPF12_RS01910 aa23bfec750765389974626efca1bb3a 416 TIGRFAM TIGR02079 THD1: threonine dehydratase 9 416 3.2E-194 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 Gene3D G3DSA:3.40.640.10 17 256 5.8E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 PIRSF PIRSF000525 1 359 7.1E-142 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 358 48.006 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 355 4.6E-143 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 SUPERFAMILY SSF53383 4 354 2.71E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 Gene3D G3DSA:3.90.1150.10 257 357 1.6E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS00895 30bccde69e67b1af574db3e4cdec3972 367 Pfam PF00266 Aminotransferase class-V 5 347 3.5E-48 T 28-03-2018 IPR000192 Aminotransferase class V domain CPF12_RS12085 d8dbea8c047e5f7485b4e114ae9e81f9 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 9.9E-28 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CPF12_RS12085 d8dbea8c047e5f7485b4e114ae9e81f9 216 SUPERFAMILY SSF161098 14 207 1.31E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS12085 d8dbea8c047e5f7485b4e114ae9e81f9 216 Gene3D G3DSA:1.10.3720.10 2 216 1.5E-40 T 28-03-2018 CPF12_RS12085 d8dbea8c047e5f7485b4e114ae9e81f9 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 214 1.1E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 SMART SM00382 30 218 1.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 SUPERFAMILY SSF52540 1 240 1.13E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 SMART SM00930 263 338 8.9E-25 T 28-03-2018 IPR018449 NIL domain CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 Gene3D G3DSA:3.40.50.300 1 254 7.0E-77 T 28-03-2018 CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 Pfam PF00005 ABC transporter 21 169 4.3E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 Gene3D G3DSA:3.30.70.260 255 340 6.3E-23 T 28-03-2018 CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 Pfam PF09383 NIL domain 266 337 6.8E-20 T 28-03-2018 IPR018449 NIL domain CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07800 2e250c40ac4d351473bcef3cd55d5299 340 SUPERFAMILY SSF55021 251 339 1.09E-21 T 28-03-2018 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 254 1.8E-86 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 SUPERFAMILY SSF88946 8 104 4.84E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 Gene3D G3DSA:1.10.10.10 183 260 9.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 4 254 1.0E-114 T 28-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 SUPERFAMILY SSF88659 173 256 2.99E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 Pfam PF04542 Sigma-70 region 2 34 104 5.8E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 Gene3D G3DSA:1.10.1740.10 18 102 1.4E-19 T 28-03-2018 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 PRINTS PR00046 Major sigma-70 factor signature 207 219 2.6E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 PRINTS PR00046 Major sigma-70 factor signature 224 239 2.6E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 PRINTS PR00046 Major sigma-70 factor signature 239 250 2.6E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 PRINTS PR00046 Major sigma-70 factor signature 59 72 2.6E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 Pfam PF04545 Sigma-70, region 4 203 252 1.2E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 Pfam PF04539 Sigma-70 region 3 114 178 3.4E-13 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 SUPERFAMILY SSF88659 108 183 5.49E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 254 1.6E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS09060 b8375edb347c5d254ec1835df091f961 261 Gene3D G3DSA:1.10.10.10 105 156 4.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 Pfam PF00005 ABC transporter 356 497 8.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 Gene3D G3DSA:3.40.50.300 319 569 3.1E-62 T 28-03-2018 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 14 539 6.6E-162 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 Gene3D G3DSA:1.20.1560.10 3 318 9.7E-36 T 28-03-2018 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 SUPERFAMILY SSF52540 325 567 2.47E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 Pfam PF00664 ABC transporter transmembrane region 16 269 7.2E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 SUPERFAMILY SSF90123 473 482 3.27E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 SUPERFAMILY SSF90123 9 296 3.27E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS05615 8b79365da0da45901e40f45787d9dcbe 570 SMART SM00382 357 559 4.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 SUPERFAMILY SSF55804 1 147 3.4E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 10 133 2.7E-36 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 172 260 7.3E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 171 251 2.0E-28 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 Gene3D G3DSA:3.40.50.2300 169 265 1.3E-34 T 28-03-2018 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 9 147 1.6E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 SUPERFAMILY SSF52794 170 266 8.37E-33 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 Pfam PF02378 Phosphotransferase system, EIIC 299 558 1.0E-12 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 Gene3D G3DSA:3.40.930.10 1 160 2.7E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS07990 8dc12cb6e1d6e0693065321c175f50f4 628 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 284 621 1.3E-110 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CPF12_RS01000 5bd31b69d065bbcb344a52d6b0fea680 247 SUPERFAMILY SSF51366 4 243 8.85E-70 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS01000 5bd31b69d065bbcb344a52d6b0fea680 247 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 7 236 4.0E-67 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01000 5bd31b69d065bbcb344a52d6b0fea680 247 Pfam PF00290 Tryptophan synthase alpha chain 8 237 1.1E-73 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01000 5bd31b69d065bbcb344a52d6b0fea680 247 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 9 244 27.961 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01000 5bd31b69d065bbcb344a52d6b0fea680 247 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 40 53 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01000 5bd31b69d065bbcb344a52d6b0fea680 247 Gene3D G3DSA:3.20.20.70 1 246 2.5E-62 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Pfam PF05043 Mga helix-turn-helix domain 84 156 1.5E-7 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Gene3D G3DSA:1.10.1790.10 271 384 7.1E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Pfam PF00874 PRD domain 293 381 6.1E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 SUPERFAMILY SSF63520 285 382 7.19E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 SUPERFAMILY SSF55804 525 673 1.83E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 529 673 6.1E-32 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 575 591 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Gene3D G3DSA:3.40.50.2300 389 477 4.2E-12 T 28-03-2018 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Gene3D G3DSA:3.40.930.10 524 676 1.6E-31 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 SUPERFAMILY SSF52794 391 470 1.41E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS10760 09ea3a292296b5d4eeab652e90519b12 681 Gene3D G3DSA:1.10.10.10 81 146 0.0096 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07260 035aa24371bad3ac17f5f64b15599598 401 Gene3D G3DSA:2.60.120.10 89 354 3.0E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS07260 035aa24371bad3ac17f5f64b15599598 401 SUPERFAMILY SSF46689 296 346 7.17E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS07260 035aa24371bad3ac17f5f64b15599598 401 SUPERFAMILY SSF46689 349 398 8.06E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS07260 035aa24371bad3ac17f5f64b15599598 401 Gene3D G3DSA:1.10.10.60 355 399 2.7E-11 T 28-03-2018 CPF12_RS07260 035aa24371bad3ac17f5f64b15599598 401 SMART SM00342 312 395 4.0E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS07260 035aa24371bad3ac17f5f64b15599598 401 Pfam PF12833 Helix-turn-helix domain 318 396 5.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 Gene3D G3DSA:3.30.70.980 175 239 1.8E-8 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 Pfam PF01709 Transcriptional regulator 4 235 3.2E-79 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 30.514 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 Gene3D G3DSA:1.10.10.200 2 76 2.2E-24 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 1.4E-70 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 53.578 T 28-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 SUPERFAMILY SSF75625 1 237 4.84E-78 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS00745 5870fcc23e83e27862a8adaf8e8deed1 239 Gene3D G3DSA:3.30.70.980 80 174 5.8E-25 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 SUPERFAMILY SSF51430 9 269 1.7E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 Pfam PF00248 Aldo/keto reductase family 33 260 2.1E-39 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PRINTS PR00069 Aldo-keto reductase signature 92 110 3.2E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PRINTS PR00069 Aldo-keto reductase signature 156 185 3.2E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PRINTS PR00069 Aldo-keto reductase signature 36 60 3.2E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PRINTS PR00069 Aldo-keto reductase signature 195 219 3.2E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PRINTS PR00069 Aldo-keto reductase signature 122 139 3.2E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PIRSF PIRSF000097 111 274 3.4E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 PIRSF PIRSF000097 2 114 4.6E-36 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02915 8cc0199e5517515c6d6cd10b515ea5f7 275 Gene3D G3DSA:3.20.20.100 2 275 4.0E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS02100 73aa32eaefbe7b38a7880e5052d4a295 354 Pfam PF00188 Cysteine-rich secretory protein family 238 338 3.3E-11 T 28-03-2018 IPR014044 CAP domain CPF12_RS02100 73aa32eaefbe7b38a7880e5052d4a295 354 SUPERFAMILY SSF55797 229 341 4.45E-13 T 28-03-2018 IPR014044 CAP domain CPF12_RS02100 73aa32eaefbe7b38a7880e5052d4a295 354 Pfam PF14504 CAP-associated N-terminal 66 206 4.8E-37 T 28-03-2018 IPR029410 CAP-associated domain CPF12_RS02100 73aa32eaefbe7b38a7880e5052d4a295 354 Gene3D G3DSA:3.40.33.10 226 347 3.2E-11 T 28-03-2018 IPR014044 CAP domain CPF12_RS06520 5d9edc48d0cac9f100683e30352c7fad 141 SUPERFAMILY SSF54637 1 138 5.57E-48 T 28-03-2018 IPR029069 HotDog domain CPF12_RS06520 5d9edc48d0cac9f100683e30352c7fad 141 Pfam PF07977 FabA-like domain 11 132 1.8E-35 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CPF12_RS06520 5d9edc48d0cac9f100683e30352c7fad 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 4 138 3.6E-56 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CPF12_RS06520 5d9edc48d0cac9f100683e30352c7fad 141 Gene3D G3DSA:3.10.129.10 1 141 1.4E-54 T 28-03-2018 CPF12_RS06520 5d9edc48d0cac9f100683e30352c7fad 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 140 32.79 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CPF12_RS04505 25bc5afea4f99acd9699f8b71d6050ec 90 SUPERFAMILY SSF52833 7 64 2.03E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS04505 25bc5afea4f99acd9699f8b71d6050ec 90 Gene3D G3DSA:3.40.30.10 6 84 2.4E-13 T 28-03-2018 CPF12_RS04505 25bc5afea4f99acd9699f8b71d6050ec 90 Pfam PF00462 Glutaredoxin 8 63 3.3E-12 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CPF12_RS06995 ecff8ba278a0be5c511491353f6594a9 340 Pfam PF01594 AI-2E family transporter 10 322 8.0E-83 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 SUPERFAMILY SSF118352 232 290 6.02E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 SUPERFAMILY SSF64397 2 241 6.15E-69 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 39.799 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 Pfam PF01430 Hsp33 protein 3 280 8.3E-88 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 PIRSF PIRSF005261 1 292 4.3E-78 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 Gene3D G3DSA:3.55.30.10 2 234 1.2E-73 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CPF12_RS05820 15af4c5fd7b5cffaf659ef5424e1eab1 294 Gene3D G3DSA:3.90.1280.10 235 288 4.6E-23 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 SMART SM01340 207 325 1.6E-49 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 305 2.0E-97 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 114 1.9E-10 T 28-03-2018 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 SUPERFAMILY SSF118116 430 616 2.09E-54 T 28-03-2018 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 SMART SM00853 432 574 7.8E-48 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 208 323 2.7E-33 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 SUPERFAMILY SSF55874 3 212 1.93E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 Pfam PF08676 MutL C terminal dimerisation domain 433 574 3.4E-46 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 Gene3D G3DSA:3.30.230.10 200 325 1.4E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 SUPERFAMILY SSF54211 188 325 3.79E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 614 27.441 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CPF12_RS11905 f645b862b77124c64f7cea0172278191 618 Gene3D G3DSA:3.30.565.10 2 199 1.3E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00645 eb7ac2cdfa5626ccb243337d9ad134cb 236 Pfam PF01061 ABC-2 type transporter 4 170 2.7E-7 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 Gene3D G3DSA:3.30.230.10 1 156 2.1E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 PRINTS PR00958 Homoserine kinase signature 236 251 4.9E-39 T 28-03-2018 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 PRINTS PR00958 Homoserine kinase signature 8 23 4.9E-39 T 28-03-2018 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 PRINTS PR00958 Homoserine kinase signature 118 131 4.9E-39 T 28-03-2018 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 PRINTS PR00958 Homoserine kinase signature 84 99 4.9E-39 T 28-03-2018 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 PRINTS PR00958 Homoserine kinase signature 156 173 4.9E-39 T 28-03-2018 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 Hamap MF_00384 Homoserine kinase [thrB]. 1 285 30.06 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 PIRSF PIRSF000676 1 286 3.6E-87 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 SUPERFAMILY SSF54211 1 143 1.37E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 Pfam PF00288 GHMP kinases N terminal domain 70 131 7.7E-14 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 Gene3D G3DSA:3.30.70.890 157 286 2.5E-21 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 SUPERFAMILY SSF55060 152 267 1.43E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 77 88 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 TIGRFAM TIGR00191 thrB: homoserine kinase 1 267 1.6E-71 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CPF12_RS09790 eca674eac0db74adc1308fc665de124f 286 Pfam PF08544 GHMP kinases C terminal 191 259 4.1E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 SMART SM00493 2 129 2.3E-19 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Pfam PF13342 C-terminal repeat of topoisomerase 637 695 3.7E-19 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Pfam PF01751 Toprim domain 4 138 2.5E-17 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 SMART SM00437 274 549 3.6E-77 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Gene3D G3DSA:3.40.50.140 1 158 3.6E-40 T 28-03-2018 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Gene3D G3DSA:1.10.460.10 473 607 3.3E-15 T 28-03-2018 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Gene3D G3DSA:1.10.460.10 164 349 1.6E-32 T 28-03-2018 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 512 526 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 316 325 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Gene3D G3DSA:2.70.20.10 352 472 1.9E-22 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 694 1.3E-167 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 311 325 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 SUPERFAMILY SSF56712 2 598 9.03E-155 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 SMART SM00436 130 225 1.8E-35 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CPF12_RS01360 c7f1275250804d3e2642ee1a238161d4 705 Pfam PF01131 DNA topoisomerase 159 584 5.0E-101 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS08085 daa1b4de10702dec4eb764f9b7b8c8d1 210 Pfam PF13460 NAD(P)H-binding 7 192 2.0E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08085 daa1b4de10702dec4eb764f9b7b8c8d1 210 SUPERFAMILY SSF51735 1 206 8.22E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08085 daa1b4de10702dec4eb764f9b7b8c8d1 210 Gene3D G3DSA:3.40.50.720 1 208 7.1E-13 T 28-03-2018 CPF12_RS05830 a4629fc84a8d4ef4460c8d70da6d4051 271 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 13 28 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CPF12_RS05830 a4629fc84a8d4ef4460c8d70da6d4051 271 Pfam PF00809 Pterin binding enzyme 14 248 1.9E-74 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CPF12_RS05830 a4629fc84a8d4ef4460c8d70da6d4051 271 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 262 4.1E-89 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CPF12_RS05830 a4629fc84a8d4ef4460c8d70da6d4051 271 SUPERFAMILY SSF51717 4 265 1.01E-89 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CPF12_RS05830 a4629fc84a8d4ef4460c8d70da6d4051 271 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 47 60 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CPF12_RS05830 a4629fc84a8d4ef4460c8d70da6d4051 271 Gene3D G3DSA:3.20.20.20 2 270 1.9E-95 T 28-03-2018 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 Gene3D G3DSA:3.50.50.60 1 51 4.2E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 Pfam PF01593 Flavin containing amine oxidoreductase 11 447 9.9E-45 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 450 3.2E-88 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 SUPERFAMILY SSF51905 420 449 1.26E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 SUPERFAMILY SSF51905 2 312 1.26E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 Gene3D G3DSA:1.10.3110.10 119 203 3.7E-27 T 28-03-2018 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 SUPERFAMILY SSF54373 295 402 1.53E-23 T 28-03-2018 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 Gene3D G3DSA:3.90.660.20 207 402 4.7E-25 T 28-03-2018 CPF12_RS03415 796c4f37bce601f23a35d5050e207060 451 Gene3D G3DSA:3.90.660.20 52 118 5.4E-8 T 28-03-2018 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 416 1.1E-102 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 176 303 8.0E-26 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 Gene3D G3DSA:1.10.1200.70 343 417 3.5E-17 T 28-03-2018 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 156 6.9E-39 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 SUPERFAMILY SSF69075 315 417 1.44E-11 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 Gene3D G3DSA:3.40.50.720 181 342 3.4E-16 T 28-03-2018 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 PIRSF PIRSF000445 1 430 6.4E-114 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 414 24.16 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 SUPERFAMILY SSF51735 161 312 1.15E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 416 1.1E-15 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS12470 93bf1b8b254008eb8d441839ef0e4a72 430 SUPERFAMILY SSF69742 1 157 6.67E-39 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CPF12_RS11315 db0b47e16e7c818da4c1397a7dc365f4 424 Pfam PF00860 Permease family 18 390 1.7E-94 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CPF12_RS11315 db0b47e16e7c818da4c1397a7dc365f4 424 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 338 358 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CPF12_RS11315 db0b47e16e7c818da4c1397a7dc365f4 424 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 14 416 2.1E-125 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CPF12_RS02150 28308d732fa2f2e114687da9a3544ef1 314 SUPERFAMILY SSF143865 13 249 4.05E-52 T 28-03-2018 CPF12_RS02150 28308d732fa2f2e114687da9a3544ef1 314 Pfam PF01544 CorA-like Mg2+ transporter protein 24 309 1.2E-61 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CPF12_RS02150 28308d732fa2f2e114687da9a3544ef1 314 Gene3D G3DSA:1.20.58.340 136 247 2.8E-13 T 28-03-2018 CPF12_RS02150 28308d732fa2f2e114687da9a3544ef1 314 SUPERFAMILY SSF144083 250 312 2.09E-15 T 28-03-2018 CPF12_RS02150 28308d732fa2f2e114687da9a3544ef1 314 Gene3D G3DSA:1.20.58.340 248 314 1.8E-12 T 28-03-2018 CPF12_RS02150 28308d732fa2f2e114687da9a3544ef1 314 Gene3D G3DSA:3.30.460.20 4 135 4.3E-19 T 28-03-2018 CPF12_RS04545 ba8524d300a38f4304d25d9dc1ffc196 377 Gene3D G3DSA:1.20.1250.20 2 190 1.5E-20 T 28-03-2018 CPF12_RS04545 ba8524d300a38f4304d25d9dc1ffc196 377 SUPERFAMILY SSF103473 4 369 1.28E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS04545 ba8524d300a38f4304d25d9dc1ffc196 377 Gene3D G3DSA:1.20.1250.20 191 374 4.4E-15 T 28-03-2018 CPF12_RS04545 ba8524d300a38f4304d25d9dc1ffc196 377 Pfam PF07690 Major Facilitator Superfamily 22 334 1.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Gene3D G3DSA:2.40.50.140 93 173 4.5E-10 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Gene3D G3DSA:2.40.50.140 5 90 2.0E-15 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SUPERFAMILY SSF50249 8 109 7.46E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SUPERFAMILY SSF50249 256 344 8.58E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SUPERFAMILY SSF50249 186 269 5.22E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 151 171 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 208 229 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 81 100 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 286 305 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 122 139 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 16 34 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 105 121 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 PRINTS PR00681 Ribosomal protein S1 signature 325 343 2.8E-44 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SMART SM00316 186 256 3.6E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SMART SM00316 100 167 8.4E-8 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SMART SM00316 271 342 7.5E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SMART SM00316 14 84 4.3E-13 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Pfam PF00575 S1 RNA binding domain 271 342 3.6E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Pfam PF00575 S1 RNA binding domain 13 77 4.4E-12 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Pfam PF00575 S1 RNA binding domain 186 256 5.5E-24 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Pfam PF00575 S1 RNA binding domain 98 167 2.1E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Gene3D G3DSA:2.40.50.140 188 272 9.9E-27 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 Gene3D G3DSA:2.40.50.140 273 372 1.9E-25 T 28-03-2018 CPF12_RS09470 4fe262a71e03b1c3b036f3ee2c5461eb 393 SUPERFAMILY SSF50249 88 169 8.67E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 SUPERFAMILY SSF51430 7 268 1.44E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 Gene3D G3DSA:3.20.20.100 2 273 1.9E-102 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 PRINTS PR00069 Aldo-keto reductase signature 38 62 6.3E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 PRINTS PR00069 Aldo-keto reductase signature 195 219 6.3E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 PRINTS PR00069 Aldo-keto reductase signature 158 187 6.3E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 PRINTS PR00069 Aldo-keto reductase signature 94 112 6.3E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 PRINTS PR00069 Aldo-keto reductase signature 124 141 6.3E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 PIRSF PIRSF000097 1 271 6.1E-89 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS02575 3197412fb6701c9cabcce4e7ccb83a4c 274 Pfam PF00248 Aldo/keto reductase family 17 260 2.4E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 TIGRFAM TIGR02415 23BDH: acetoin reductases 3 257 7.1E-105 T 28-03-2018 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 Gene3D G3DSA:3.40.50.720 1 257 4.4E-65 T 28-03-2018 CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 254 2.0E-56 T 28-03-2018 CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 4.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 SUPERFAMILY SSF51735 3 255 9.13E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11420 9d0fa78b1ccdeb0d6381639b8e16d69c 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 201 511 3.3E-154 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Gene3D G3DSA:3.40.50.880 2 210 2.1E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Pfam PF00117 Glutamine amidotransferase class-I 9 189 5.3E-43 T 28-03-2018 IPR017926 Glutamine amidotransferase CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00097 Anthranilate synthase component II signature 78 89 4.4E-5 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00097 Anthranilate synthase component II signature 166 179 4.4E-5 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00097 Anthranilate synthase component II signature 51 60 4.4E-5 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 SUPERFAMILY SSF52402 186 404 2.21E-62 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Gene3D G3DSA:3.30.300.10 387 511 1.1E-51 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 7 194 6.0E-82 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 SUPERFAMILY SSF52317 4 226 3.3E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Gene3D G3DSA:3.40.50.620 211 386 1.1E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Pfam PF02540 NAD synthase 210 283 1.3E-6 T 28-03-2018 IPR022310 NAD/GMP synthase CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 SUPERFAMILY SSF54810 391 511 1.57E-49 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 4 511 54.948 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 Pfam PF00958 GMP synthase C terminal domain 419 510 3.4E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 4.3E-7 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 4.3E-7 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 7 21 4.3E-7 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 1.7E-7 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 1.7E-7 T 28-03-2018 CPF12_RS00825 8ff2c9df1891840075bef1cd57578e15 511 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 1.7E-7 T 28-03-2018 CPF12_RS04555 6c6f807ff46749dce15ebcab79d4aa94 130 Pfam PF04138 GtrA-like protein 12 129 1.1E-24 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 SUPERFAMILY SSF81338 8 241 4.06E-69 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 Pfam PF00230 Major intrinsic protein 9 236 2.8E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 TIGRFAM TIGR00861 MIP: MIP family channel proteins 13 236 3.6E-57 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 PRINTS PR00783 Major intrinsic protein family signature 142 160 2.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 PRINTS PR00783 Major intrinsic protein family signature 219 239 2.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 PRINTS PR00783 Major intrinsic protein family signature 8 27 2.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 PRINTS PR00783 Major intrinsic protein family signature 50 74 2.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 PRINTS PR00783 Major intrinsic protein family signature 87 106 2.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 PRINTS PR00783 Major intrinsic protein family signature 172 194 2.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 ProSitePatterns PS00221 MIP family signature. 68 76 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06835 4488ebf09ebda2fcad94e9d481b2db2e 270 Gene3D G3DSA:1.20.1080.10 1 244 6.6E-83 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS09530 ed50df0d7ad6a6b58d1fb570f657811c 124 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 119 3.8E-41 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09530 ed50df0d7ad6a6b58d1fb570f657811c 124 Pfam PF07736 Chorismate mutase type I 3 119 3.5E-42 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09530 ed50df0d7ad6a6b58d1fb570f657811c 124 SUPERFAMILY SSF55298 1 122 2.83E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS09530 ed50df0d7ad6a6b58d1fb570f657811c 124 PIRSF PIRSF005965 1 124 1.1E-45 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09530 ed50df0d7ad6a6b58d1fb570f657811c 124 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 120 5.0E-21 T 28-03-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09530 ed50df0d7ad6a6b58d1fb570f657811c 124 Gene3D G3DSA:3.30.1330.40 3 120 1.8E-44 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS04335 044df28c161840c8a4def366f6a8e7e2 434 Pfam PF16781 Domain of unknown function (DUF5068) 87 233 9.1E-10 T 28-03-2018 IPR031888 Protein of unknown function DUF5068 CPF12_RS04335 044df28c161840c8a4def366f6a8e7e2 434 Gene3D G3DSA:2.60.40.1240 82 283 4.9E-8 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CPF12_RS04335 044df28c161840c8a4def366f6a8e7e2 434 Gene3D G3DSA:2.60.40.1240 290 433 2.1E-8 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CPF12_RS07625 356ff12ed236a0e35345736fe7d3f871 325 SUPERFAMILY SSF51395 15 320 3.66E-60 T 28-03-2018 CPF12_RS07625 356ff12ed236a0e35345736fe7d3f871 325 Gene3D G3DSA:1.10.1200.80 252 323 4.8E-10 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CPF12_RS07625 356ff12ed236a0e35345736fe7d3f871 325 Gene3D G3DSA:3.20.20.70 12 250 3.3E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS07625 356ff12ed236a0e35345736fe7d3f871 325 Pfam PF01207 Dihydrouridine synthase (Dus) 17 319 1.9E-50 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CPF12_RS07625 356ff12ed236a0e35345736fe7d3f871 325 PIRSF PIRSF006621 4 324 9.6E-82 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CPF12_RS07625 356ff12ed236a0e35345736fe7d3f871 325 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 101 119 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CPF12_RS03235 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS03235 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03235 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03235 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS10270 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS10270 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS10270 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS10270 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS11565 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS11565 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS11565 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS11565 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS03570 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS03570 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03570 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03570 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS06955 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS06955 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS06955 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS06955 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS08645 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS08645 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08645 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08645 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS06940 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS06940 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS06940 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS06940 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS08460 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS08460 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08460 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08460 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS03505 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS03505 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03505 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03505 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS02765 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS02765 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS02765 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS02765 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS08805 722d0d82e48f7b1d345c37ffdd2fe12f 319 Pfam PF00665 Integrase core domain 161 265 9.9E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS08805 722d0d82e48f7b1d345c37ffdd2fe12f 319 SUPERFAMILY SSF53098 160 309 3.03E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08805 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:3.30.420.10 152 317 5.2E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS08805 722d0d82e48f7b1d345c37ffdd2fe12f 319 Gene3D G3DSA:1.10.10.60 3 46 5.2E-5 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 SMART SM00436 104 192 2.9E-48 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 SMART SM00493 3 103 1.3E-31 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:1.10.460.10 135 326 1.1E-50 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 SUPERFAMILY SSF56712 4 589 1.31E-199 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Pfam PF01131 DNA topoisomerase 128 548 6.8E-136 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 6.1E-260 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:3.40.50.140 2 129 1.9E-38 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:3.30.65.10 560 614 2.9E-17 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:3.30.65.10 615 652 3.8E-8 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:3.30.65.10 653 692 5.2E-4 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 9.9E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 9.9E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 9.9E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 9.9E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 9.9E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 691 0.014 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 655 2.9E-12 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 612 1.1E-14 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:2.70.20.10 327 445 2.4E-41 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 633 55.856 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 SUPERFAMILY SSF57783 576 613 1.87E-13 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Pfam PF01751 Toprim domain 5 113 6.1E-30 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 Gene3D G3DSA:1.10.460.10 446 559 4.3E-31 T 28-03-2018 CPF12_RS11810 ad80cded5a3d5e0235303afb5be6135f 692 SMART SM00437 242 510 4.6E-124 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Gene3D G3DSA:3.40.50.620 22 194 4.9E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Gene3D G3DSA:1.10.730.10 521 745 5.8E-78 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Gene3D G3DSA:3.90.740.10 243 433 1.3E-61 T 28-03-2018 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 877 15.847 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 859 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 812 876 9.2E-20 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 563 6.5E-214 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 SUPERFAMILY SSF47323 574 827 2.8E-72 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Gene3D G3DSA:1.10.287.380 805 875 5.1E-24 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Pfam PF08264 Anticodon-binding domain of tRNA 606 751 3.3E-42 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 SUPERFAMILY SSF46589 812 876 7.85E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 SUPERFAMILY SSF52374 8 198 4.33E-140 T 28-03-2018 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 SUPERFAMILY SSF52374 346 573 4.33E-140 T 28-03-2018 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 SUPERFAMILY SSF50677 196 347 3.4E-63 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 5.5E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 PRINTS PR00986 Valyl-tRNA synthetase signature 475 493 5.5E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 5.5E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 5.5E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 PRINTS PR00986 Valyl-tRNA synthetase signature 443 464 5.5E-36 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Gene3D G3DSA:3.40.50.620 434 520 1.0E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS01125 86b8e8d3bb38283937ff84af4b82429c 879 Gene3D G3DSA:3.90.740.10 195 242 6.8E-16 T 28-03-2018 CPF12_RS03740 636d7c2298b7f4c742b34ec2de0385fe 204 SUPERFAMILY SSF81301 9 202 1.19E-54 T 28-03-2018 CPF12_RS03740 636d7c2298b7f4c742b34ec2de0385fe 204 Gene3D G3DSA:1.10.287.860 155 203 1.9E-16 T 28-03-2018 CPF12_RS03740 636d7c2298b7f4c742b34ec2de0385fe 204 SMART SM00954 49 172 1.2E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CPF12_RS03740 636d7c2298b7f4c742b34ec2de0385fe 204 Pfam PF04607 Region found in RelA / SpoT proteins 49 169 2.9E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CPF12_RS03740 636d7c2298b7f4c742b34ec2de0385fe 204 Gene3D G3DSA:3.30.460.10 4 153 2.1E-37 T 28-03-2018 CPF12_RS11555 16d1e397983f9e2751085912e541d0ac 311 SMART SM00382 30 214 6.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11555 16d1e397983f9e2751085912e541d0ac 311 SUPERFAMILY SSF52540 2 235 4.66E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11555 16d1e397983f9e2751085912e541d0ac 311 Gene3D G3DSA:3.40.50.300 1 289 1.3E-56 T 28-03-2018 CPF12_RS11555 16d1e397983f9e2751085912e541d0ac 311 Pfam PF00005 ABC transporter 21 165 1.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11405 1c24e09d47f24689080a29bd9bb90fc7 405 Gene3D G3DSA:1.20.1250.20 6 201 4.4E-38 T 28-03-2018 CPF12_RS11405 1c24e09d47f24689080a29bd9bb90fc7 405 ProSitePatterns PS00216 Sugar transport proteins signature 1. 275 290 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CPF12_RS11405 1c24e09d47f24689080a29bd9bb90fc7 405 SUPERFAMILY SSF103473 9 404 6.54E-87 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS11405 1c24e09d47f24689080a29bd9bb90fc7 405 Pfam PF07690 Major Facilitator Superfamily 25 268 2.0E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS11405 1c24e09d47f24689080a29bd9bb90fc7 405 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CPF12_RS11405 1c24e09d47f24689080a29bd9bb90fc7 405 Gene3D G3DSA:1.20.1250.20 202 405 1.1E-30 T 28-03-2018 CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 5.7E-24 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 6.3E-99 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 SUPERFAMILY SSF56219 1 251 3.4E-80 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 3.8E-97 T 28-03-2018 CPF12_RS08420 d93bbcc24fa9612363c5e4750bff34cb 251 Gene3D G3DSA:3.60.10.10 1 251 5.1E-56 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 Pfam PF00206 Lyase 6 286 8.9E-74 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 Gene3D G3DSA:1.10.275.10 2 92 4.4E-25 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 Gene3D G3DSA:1.20.200.10 93 348 2.2E-80 T 28-03-2018 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 SUPERFAMILY SSF48557 3 427 5.65E-139 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 Gene3D G3DSA:1.10.40.30 349 428 2.4E-22 T 28-03-2018 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 1.2E-174 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 SMART SM00998 349 429 1.4E-34 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 1.3E-22 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 4.4E-9 T 28-03-2018 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 4.4E-9 T 28-03-2018 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 4.4E-9 T 28-03-2018 CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 4.8E-27 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS08680 ce33540a7f9a9c01753a23eb538f4ad0 433 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CPF12_RS09885 7752cc836a6e8d70fca781fbad56b9dd 306 Gene3D G3DSA:3.40.50.1980 35 144 7.0E-19 T 28-03-2018 CPF12_RS09885 7752cc836a6e8d70fca781fbad56b9dd 306 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 15 304 9.2E-123 T 28-03-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 CPF12_RS09885 7752cc836a6e8d70fca781fbad56b9dd 306 Gene3D G3DSA:3.40.50.1980 145 305 3.8E-34 T 28-03-2018 CPF12_RS09885 7752cc836a6e8d70fca781fbad56b9dd 306 Pfam PF01497 Periplasmic binding protein 53 282 4.9E-41 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CPF12_RS09885 7752cc836a6e8d70fca781fbad56b9dd 306 SUPERFAMILY SSF53807 50 304 3.49E-53 T 28-03-2018 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 Pfam PF09334 tRNA synthetases class I (M) 8 374 1.3E-115 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 Gene3D G3DSA:2.40.50.140 555 664 3.8E-27 T 28-03-2018 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 498 1.1E-172 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 SUPERFAMILY SSF52374 5 361 1.26E-113 T 28-03-2018 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 SUPERFAMILY SSF47323 365 576 4.58E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 2.0E-30 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 2.0E-30 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 PRINTS PR01041 Methionyl-tRNA synthetase signature 362 373 2.0E-30 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 2.0E-30 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 PRINTS PR01041 Methionyl-tRNA synthetase signature 237 248 2.0E-30 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 PRINTS PR01041 Methionyl-tRNA synthetase signature 270 285 2.0E-30 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 Gene3D G3DSA:1.10.730.10 359 527 2.3E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 529 664 2.4E-42 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 Hamap MF_01228 Methionine--tRNA ligase [metG]. 3 525 50.649 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 SUPERFAMILY SSF50249 562 662 3.92E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 Gene3D G3DSA:3.40.50.620 5 358 1.6E-101 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS05705 9f138290dc02654c5939a968381bdae7 664 Pfam PF01588 Putative tRNA binding domain 569 661 7.8E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 Pfam PF11967 Recombination protein O N terminal 1 76 1.6E-25 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 SUPERFAMILY SSF57863 80 231 1.36E-38 T 28-03-2018 CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 Gene3D G3DSA:2.40.50.140 1 80 4.6E-25 T 28-03-2018 CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 Pfam PF02565 Recombination protein O C terminal 82 236 1.9E-37 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 Hamap MF_00201 DNA repair protein RecO [recO]. 1 242 27.641 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 242 1.6E-71 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CPF12_RS11080 fe0ec0ac06ee2695d70c3afad60c70eb 257 SUPERFAMILY SSF50249 2 77 3.26E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 1.5E-82 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 SUPERFAMILY SSF53067 254 493 6.11E-84 T 28-03-2018 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 Gene3D G3DSA:3.30.420.40 1 249 1.3E-84 T 28-03-2018 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 Gene3D G3DSA:3.30.420.40 250 495 3.7E-77 T 28-03-2018 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 58.388 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 SUPERFAMILY SSF53067 4 255 7.2E-95 T 28-03-2018 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 494 2.2E-218 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 450 3.2E-61 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CPF12_RS06840 79941b5d59bfd4951a41577eac0745e1 497 PIRSF PIRSF000538 3 496 9.6E-177 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 Pfam PF00137 ATP synthase subunit C 6 68 3.1E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 Hamap MF_01396 ATP synthase subunit c [atpH]. 5 70 16.196 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 PRINTS PR00124 ATP synthase C subunit signature 45 70 3.8E-21 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 PRINTS PR00124 ATP synthase C subunit signature 28 43 3.8E-21 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 PRINTS PR00124 ATP synthase C subunit signature 7 26 3.8E-21 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 16 70 3.0E-22 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 ProSitePatterns PS00605 ATP synthase c subunit signature. 35 56 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 Gene3D G3DSA:1.20.20.10 1 71 6.0E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CPF12_RS06470 7daadd60101000d9dca3ceeb8b42f7e0 72 SUPERFAMILY SSF81333 2 71 3.14E-20 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CPF12_RS03785 4de5faf60c580c986746657f6a69b09b 296 Pfam PF12849 PBP superfamily domain 34 266 1.8E-40 T 28-03-2018 IPR024370 PBP domain CPF12_RS03785 4de5faf60c580c986746657f6a69b09b 296 Gene3D G3DSA:3.40.190.10 36 171 3.6E-33 T 28-03-2018 CPF12_RS03785 4de5faf60c580c986746657f6a69b09b 296 SUPERFAMILY SSF53850 40 289 4.41E-72 T 28-03-2018 CPF12_RS03785 4de5faf60c580c986746657f6a69b09b 296 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 279 3.4E-80 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CPF12_RS03785 4de5faf60c580c986746657f6a69b09b 296 Gene3D G3DSA:3.40.190.10 172 291 3.5E-18 T 28-03-2018 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 SUPERFAMILY SSF56327 144 307 1.44E-52 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 173 179 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 Gene3D G3DSA:3.40.50.720 5 143 4.4E-32 T 28-03-2018 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 PIRSF PIRSF000102 2 311 1.8E-103 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 143 1.7E-43 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 Gene3D G3DSA:3.90.110.10 144 311 1.3E-50 T 28-03-2018 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 4 310 43.984 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 SUPERFAMILY SSF51735 3 145 3.88E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 PRINTS PR00086 L-lactate dehydrogenase signature 31 55 6.5E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 6.5E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 PRINTS PR00086 L-lactate dehydrogenase signature 6 30 6.5E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 6.5E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 6.5E-43 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 309 1.2E-35 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CPF12_RS05760 e2572f3fe1ab414416b22fa6048acc6a 315 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 9 304 1.2E-119 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS06605 3ead3d2ee620af0e02f9d7b2f1663389 359 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 246 3.1E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CPF12_RS06605 3ead3d2ee620af0e02f9d7b2f1663389 359 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 246 4.0E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 Gene3D G3DSA:1.10.10.60 147 206 8.6E-16 T 28-03-2018 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 SMART SM00342 174 257 1.4E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 SMART SM00448 2 116 4.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 Pfam PF00072 Response regulator receiver domain 4 116 1.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 SUPERFAMILY SSF46689 159 208 3.31E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 Pfam PF12833 Helix-turn-helix domain 180 257 4.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 Gene3D G3DSA:1.10.10.60 207 266 1.8E-11 T 28-03-2018 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 SUPERFAMILY SSF52172 1 148 5.12E-32 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 Gene3D G3DSA:3.40.50.2300 1 145 9.1E-29 T 28-03-2018 CPF12_RS04405 cbcd22c1762b844877cb6e2c20462cf7 272 SUPERFAMILY SSF46689 210 258 8.96E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 6.8E-181 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 SUPERFAMILY SSF47648 1 69 2.22E-22 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 PIRSF PIRSF000478 1 432 8.6E-167 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 SUPERFAMILY SSF52418 69 329 1.24E-89 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 Pfam PF00591 Glycosyl transferase family, a/b domain 77 306 3.3E-47 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 SUPERFAMILY SSF54680 331 430 2.75E-30 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 SMART SM00941 345 418 5.2E-32 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 Gene3D G3DSA:1.20.970.10 1 66 2.3E-25 T 28-03-2018 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 Gene3D G3DSA:3.90.1170.30 338 423 2.8E-28 T 28-03-2018 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.6E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 Gene3D G3DSA:3.40.1030.10 68 337 1.2E-91 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 9.5E-28 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS10320 3733151157a29af26a0c77d1b5abfc0b 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 227 44.256 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 124 3.1E-30 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 1 227 7.3E-113 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 PIRSF PIRSF000709 2 116 1.3E-9 T 28-03-2018 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 PIRSF PIRSF000709 170 226 0.019 T 28-03-2018 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 Gene3D G3DSA:3.40.50.1240 1 228 3.2E-62 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 SMART SM00855 2 188 2.6E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CPF12_RS02735 5e9c4768e72921eb739e6deabd00f211 228 SUPERFAMILY SSF53254 1 223 6.68E-75 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS05385 80ddba4c1c912de4ebc3ca752d2b5822 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 22.122 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS05385 80ddba4c1c912de4ebc3ca752d2b5822 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 2.5E-29 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05385 80ddba4c1c912de4ebc3ca752d2b5822 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS05385 80ddba4c1c912de4ebc3ca752d2b5822 96 Gene3D G3DSA:3.30.70.60 1 96 7.6E-27 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CPF12_RS05385 80ddba4c1c912de4ebc3ca752d2b5822 96 Pfam PF01250 Ribosomal protein S6 3 92 3.9E-25 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05385 80ddba4c1c912de4ebc3ca752d2b5822 96 SUPERFAMILY SSF54995 1 95 6.15E-31 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 SUPERFAMILY SSF51230 3 95 1.31E-25 T 28-03-2018 IPR011053 Single hybrid motif CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Pfam PF02817 e3 binding domain 135 170 1.3E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 SUPERFAMILY SSF47005 129 174 1.96E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Gene3D G3DSA:3.30.559.10 195 438 1.0E-91 T 28-03-2018 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Gene3D G3DSA:4.10.320.10 135 194 9.4E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Pfam PF00364 Biotin-requiring enzyme 5 76 6.0E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 SUPERFAMILY SSF52777 197 436 5.34E-89 T 28-03-2018 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Gene3D G3DSA:3.90.1170.30 2 45 5.8E-13 T 28-03-2018 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Gene3D G3DSA:3.90.1170.30 46 134 3.6E-5 T 28-03-2018 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 207 436 1.2E-88 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS02195 feecdb2591df1aaa080652e41a2bb9c1 438 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 PRINTS PR00958 Homoserine kinase signature 168 185 2.3E-5 T 28-03-2018 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 PRINTS PR00958 Homoserine kinase signature 240 255 2.3E-5 T 28-03-2018 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 PRINTS PR00958 Homoserine kinase signature 7 22 2.3E-5 T 28-03-2018 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 PRINTS PR00958 Homoserine kinase signature 103 118 2.3E-5 T 28-03-2018 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 SUPERFAMILY SSF55060 161 280 7.55E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 Gene3D G3DSA:3.30.230.10 3 159 5.1E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 283 4.7E-91 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 Gene3D G3DSA:3.30.70.890 161 284 6.3E-27 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 Pfam PF00288 GHMP kinases N terminal domain 87 144 1.2E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 34.865 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 SUPERFAMILY SSF54211 1 158 5.77E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 PIRSF PIRSF010376 1 285 9.5E-95 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CPF12_RS05735 44e87374805a9cff2056be2803ab6a3b 287 Pfam PF08544 GHMP kinases C terminal 198 273 1.4E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 PIRSF PIRSF015950 1 322 3.0E-118 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 SUPERFAMILY SSF55060 172 303 2.81E-41 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 4 300 1.7E-106 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 SUPERFAMILY SSF54211 1 164 8.35E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 Gene3D G3DSA:3.30.70.890 172 306 3.4E-43 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 Pfam PF08544 GHMP kinases C terminal 217 300 6.7E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 Pfam PF00288 GHMP kinases N terminal domain 86 135 4.6E-6 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CPF12_RS05080 da4fab9dad1ab35627cd5b3c2c981ecf 322 Gene3D G3DSA:3.30.230.10 1 171 5.5E-59 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 SUPERFAMILY SSF51905 2 350 8.03E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 293 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 189 214 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 1.0E-66 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 361 469 2.9E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PIRSF PIRSF000350 1 478 3.1E-80 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 Gene3D G3DSA:3.50.50.60 2 177 6.9E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 479 7.6E-168 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 341 2.9E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 Gene3D G3DSA:3.30.390.30 349 478 1.7E-41 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 5.6E-34 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.6E-34 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 5.6E-34 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 294 5.6E-34 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 189 207 5.6E-34 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 Gene3D G3DSA:3.40.50.720 178 348 1.5E-31 T 28-03-2018 CPF12_RS01805 637357b9103f8c68d78408bbb9a79707 480 SUPERFAMILY SSF55424 358 479 7.39E-41 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 SUPERFAMILY SSF52440 1 102 1.44E-30 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 SUPERFAMILY SSF51246 326 420 1.88E-23 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Gene3D G3DSA:3.30.470.20 190 325 1.1E-52 T 28-03-2018 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 SMART SM01210 327 420 3.7E-31 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 418 6.5E-22 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 SMART SM01209 102 294 4.4E-123 T 28-03-2018 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Gene3D G3DSA:3.40.50.20 2 85 1.7E-31 T 28-03-2018 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 39.388 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 3.1E-31 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 1.3E-149 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Gene3D G3DSA:3.30.1490.20 86 188 7.7E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Gene3D G3DSA:3.90.600.10 327 421 4.7E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 294 4.2E-78 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08725 756c91f5d0fce5f977e35c355f0ed491 435 SUPERFAMILY SSF56059 103 321 3.18E-58 T 28-03-2018 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 SMART SM00738 2 113 3.5E-52 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 SMART SM00739 123 150 1.5E-4 T 28-03-2018 IPR005824 KOW CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 SUPERFAMILY SSF50104 121 177 1.5E-17 T 28-03-2018 IPR008991 Translation protein SH3-like domain CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.3E-17 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.3E-17 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.3E-17 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 Gene3D G3DSA:3.30.70.940 2 116 3.5E-44 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 Pfam PF00467 KOW motif 127 159 7.7E-7 T 28-03-2018 IPR005824 KOW CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 Pfam PF02357 Transcription termination factor nusG 3 109 2.6E-28 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 5.7E-62 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 SUPERFAMILY SSF82679 3 113 1.02E-40 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 27.423 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CPF12_RS05990 d53b174369237e2cb5988fef19a33091 177 Gene3D G3DSA:2.30.30.30 118 177 2.0E-19 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 SMART SM01217 639 708 2.2E-16 T 28-03-2018 IPR026891 Fibronectin type III-like domain CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 SUPERFAMILY SSF51445 6 371 1.9E-92 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 Gene3D G3DSA:2.60.40.10 605 722 6.2E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 Gene3D G3DSA:3.40.50.1700 359 604 8.3E-71 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 Gene3D G3DSA:3.20.20.300 1 358 1.2E-94 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 16 335 3.4E-67 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 Pfam PF14310 Fibronectin type III-like domain 639 708 4.0E-15 T 28-03-2018 IPR026891 Fibronectin type III-like domain CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 100 119 2.5E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 186 202 2.5E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 81 97 2.5E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 146 162 2.5E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 PRINTS PR00133 Glycosyl hydrolase family 3 signature 256 274 2.5E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 256 273 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 SUPERFAMILY SSF52279 372 602 7.98E-45 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS02465 01b02af2fb0cd2b382808fe75ace391d 723 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 373 602 2.6E-49 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CPF12_RS08005 3d66d8181c35cd101ed03810c5f7ec58 367 Gene3D G3DSA:3.40.50.1820 16 366 9.3E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08005 3d66d8181c35cd101ed03810c5f7ec58 367 PIRSF PIRSF000443 1 366 1.9E-117 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CPF12_RS08005 3d66d8181c35cd101ed03810c5f7ec58 367 Pfam PF00561 alpha/beta hydrolase fold 41 343 1.9E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS08005 3d66d8181c35cd101ed03810c5f7ec58 367 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 11 357 2.9E-121 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CPF12_RS08005 3d66d8181c35cd101ed03810c5f7ec58 367 SUPERFAMILY SSF53474 5 359 1.15E-88 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08005 3d66d8181c35cd101ed03810c5f7ec58 367 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 1 359 39.896 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CPF12_RS10740 ff505445f26b3e37e6959a9fdc238f57 280 SUPERFAMILY SSF52518 4 259 5.66E-76 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS10740 ff505445f26b3e37e6959a9fdc238f57 280 Gene3D G3DSA:3.40.50.970 1 276 2.6E-63 T 28-03-2018 CPF12_RS10740 ff505445f26b3e37e6959a9fdc238f57 280 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 250 2.9E-46 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS08965 a2304134fb965ad881cbc97cbbf1fd39 259 SUPERFAMILY SSF52540 4 225 3.14E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08965 a2304134fb965ad881cbc97cbbf1fd39 259 Gene3D G3DSA:3.40.50.300 1 233 2.2E-61 T 28-03-2018 CPF12_RS08965 a2304134fb965ad881cbc97cbbf1fd39 259 SMART SM00382 33 221 1.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS08965 a2304134fb965ad881cbc97cbbf1fd39 259 Pfam PF00005 ABC transporter 25 172 3.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 SMART SM00760 355 424 5.2E-41 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Gene3D G3DSA:1.10.1750.10 349 446 5.7E-35 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 34.028 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Gene3D G3DSA:3.40.50.300 108 275 2.1E-23 T 28-03-2018 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 445 1.2E-183 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 SUPERFAMILY SSF48295 342 446 3.14E-35 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Pfam PF11638 DnaA N-terminal domain 6 66 1.5E-10 T 28-03-2018 IPR024633 DnaA N-terminal domain CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 SUPERFAMILY SSF52540 110 323 1.54E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Pfam PF00308 Bacterial dnaA protein 111 327 8.8E-106 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 SMART SM00382 143 271 4.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Gene3D G3DSA:1.10.8.60 277 348 2.4E-28 T 28-03-2018 CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 1.6E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 1.6E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 1.6E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 1.6E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 1.6E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CPF12_RS05495 a26d2ad52aa821e911405b8160bfef3c 447 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 357 424 2.7E-30 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CPF12_RS03820 e3464eda794d26755b46cf26b5f1d18e 328 Gene3D G3DSA:2.60.40.10 193 291 0.063 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS03820 e3464eda794d26755b46cf26b5f1d18e 328 Pfam PF06030 Bacterial protein of unknown function (DUF916) 34 151 4.2E-31 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CPF12_RS03820 e3464eda794d26755b46cf26b5f1d18e 328 Gene3D G3DSA:2.60.40.1710 42 180 6.3E-5 T 28-03-2018 CPF12_RS03820 e3464eda794d26755b46cf26b5f1d18e 328 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 158 292 2.3E-25 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CPF12_RS06925 d9fae100a6598e2841cba6d2b0a68fe8 136 Gene3D G3DSA:3.40.30.10 1 131 3.1E-36 T 28-03-2018 CPF12_RS06925 d9fae100a6598e2841cba6d2b0a68fe8 136 Pfam PF03960 ArsC family 5 113 1.1E-17 T 28-03-2018 IPR006660 Arsenate reductase-like CPF12_RS06925 d9fae100a6598e2841cba6d2b0a68fe8 136 SUPERFAMILY SSF52833 1 125 8.42E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS06925 d9fae100a6598e2841cba6d2b0a68fe8 136 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 1.1E-34 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CPF12_RS10985 fc70985b4a5c1cc77b3b411237c19221 293 Hamap MF_01672 Inosose dehydratase [iolE]. 1 292 51.962 T 28-03-2018 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 CPF12_RS10985 fc70985b4a5c1cc77b3b411237c19221 293 SUPERFAMILY SSF51658 5 288 7.6E-49 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS10985 fc70985b4a5c1cc77b3b411237c19221 293 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 3 288 1.9E-113 T 28-03-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 CPF12_RS10985 fc70985b4a5c1cc77b3b411237c19221 293 Gene3D G3DSA:3.20.20.150 1 293 2.2E-46 T 28-03-2018 CPF12_RS10985 fc70985b4a5c1cc77b3b411237c19221 293 Pfam PF01261 Xylose isomerase-like TIM barrel 49 214 1.5E-20 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 SUPERFAMILY SSF46785 258 328 1.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 4.2E-35 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 327 3.0E-26 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 6.1E-146 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 Gene3D G3DSA:1.10.8.60 185 255 1.1E-27 T 28-03-2018 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 1.8E-114 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 SUPERFAMILY SSF52540 21 254 1.02E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 Gene3D G3DSA:3.40.50.300 19 182 2.1E-29 T 28-03-2018 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 SMART SM00382 52 183 4.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 331 168.942 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CPF12_RS01880 0d019608cc0a7163dbdb198e47e33523 331 Gene3D G3DSA:1.10.10.10 258 328 4.3E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 SUPERFAMILY SSF46946 2 113 2.62E-43 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 Gene3D G3DSA:4.10.910.10 67 85 5.9E-16 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 PIRSF PIRSF002134 1 121 9.7E-43 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 Gene3D G3DSA:4.10.910.10 86 121 2.5E-25 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 Gene3D G3DSA:1.10.8.50 1 66 4.3E-25 T 28-03-2018 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 4.3E-32 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 6.9E-51 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.625 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06180 cdf1d8e9d89d3224e57b66ff21febf5c 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 SUPERFAMILY SSF55021 348 414 3.52E-6 T 28-03-2018 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 Pfam PF00742 Homoserine dehydrogenase 137 315 3.3E-62 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 Gene3D G3DSA:3.40.50.720 2 160 1.6E-29 T 28-03-2018 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 PIRSF PIRSF000098 1 426 4.4E-164 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 Gene3D G3DSA:3.30.360.10 161 298 1.9E-50 T 28-03-2018 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 SUPERFAMILY SSF55347 137 302 2.88E-51 T 28-03-2018 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 Gene3D G3DSA:3.30.70.260 346 423 5.3E-6 T 28-03-2018 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 2.7E-19 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CPF12_RS09800 fb362441cdb1ba1ec6cefeca9476a9f6 426 SUPERFAMILY SSF51735 1 158 1.84E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00925 24f688515e770927fb48e75045b96f55 273 Gene3D G3DSA:3.60.10.10 1 271 9.5E-28 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CPF12_RS00925 24f688515e770927fb48e75045b96f55 273 SUPERFAMILY SSF56219 1 270 7.59E-28 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CPF12_RS00925 24f688515e770927fb48e75045b96f55 273 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 18 265 1.1E-10 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 197 526 35.068 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Pfam PF00591 Glycosyl transferase family, a/b domain 269 516 5.7E-86 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Gene3D G3DSA:3.40.50.880 1 190 3.8E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 SUPERFAMILY SSF47648 195 261 1.57E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 4.2E-66 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 SUPERFAMILY SSF52418 267 524 3.27E-85 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 SUPERFAMILY SSF52317 1 190 1.87E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Gene3D G3DSA:1.20.970.10 191 267 2.4E-18 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Pfam PF00117 Glutamine amidotransferase class-I 3 187 4.8E-53 T 28-03-2018 IPR017926 Glutamine amidotransferase CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.3E-31 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.3E-31 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.3E-31 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.3E-31 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.3E-31 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.3E-31 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 6.4E-13 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 6.4E-13 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 6.4E-13 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 5.1E-8 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 5.1E-8 T 28-03-2018 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Pfam PF02885 Glycosyl transferase family, helical bundle domain 198 258 1.4E-14 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 201 524 8.1E-112 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CPF12_RS01020 866100a34a6980ba18033ff62c5d65c2 532 Gene3D G3DSA:3.40.1030.10 268 532 1.4E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 8 68 14.435 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 8 48 3.0E-6 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 Pfam PF02609 Exonuclease VII small subunit 9 58 4.3E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 Gene3D G3DSA:1.10.287.1040 6 71 1.5E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 8 63 3.3E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 PIRSF PIRSF006488 1 78 8.5E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09225 c272b2426714935881d901bfb0c128c2 78 SUPERFAMILY SSF116842 3 72 1.96E-19 T 28-03-2018 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 Pfam PF01791 DeoC/LacD family aldolase 3 206 1.5E-20 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 214 33.564 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 SMART SM01133 2 212 1.0E-93 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 PIRSF PIRSF001357 1 214 6.1E-77 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 SUPERFAMILY SSF51569 2 213 5.65E-80 T 28-03-2018 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 Gene3D G3DSA:3.20.20.70 1 214 4.8E-93 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS08345 ad04ed167bbb728ee8f09094efa20046 214 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 213 4.9E-84 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 PIRSF PIRSF000850 378 487 0.017 T 28-03-2018 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 PIRSF PIRSF000850 102 378 0.019 T 28-03-2018 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 59 4.8E-11 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 SUPERFAMILY SSF56024 102 318 4.71E-53 T 28-03-2018 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 Gene3D G3DSA:3.30.870.10 111 308 1.3E-33 T 28-03-2018 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 6 488 5.8E-186 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 Gene3D G3DSA:3.30.870.10 315 482 1.8E-33 T 28-03-2018 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 Pfam PF13091 PLD-like domain 139 250 1.1E-12 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 Pfam PF13091 PLD-like domain 329 453 1.2E-25 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 SUPERFAMILY SSF56024 272 475 4.04E-53 T 28-03-2018 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 SMART SM00155 401 428 3.8E-7 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 SMART SM00155 220 247 7.1E-7 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CPF12_RS06675 00110670b3d210babb303ae0ac1647e2 488 Hamap MF_01916 Cardiolipin synthase. 12 488 44.298 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CPF12_RS06785 fde914e03f51878e055bfe9b5c5296d5 505 Pfam PF14559 Tetratricopeptide repeat 26 90 1.0E-6 T 28-03-2018 CPF12_RS06785 fde914e03f51878e055bfe9b5c5296d5 505 SUPERFAMILY SSF48452 165 282 3.56E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS06785 fde914e03f51878e055bfe9b5c5296d5 505 Gene3D G3DSA:1.25.40.10 12 139 1.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS06785 fde914e03f51878e055bfe9b5c5296d5 505 Gene3D G3DSA:1.25.40.10 150 329 3.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS06785 fde914e03f51878e055bfe9b5c5296d5 505 SUPERFAMILY SSF48452 15 134 5.06E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 SUPERFAMILY SSF51445 2 473 1.76E-162 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 Gene3D G3DSA:3.20.20.80 2 480 1.2E-154 T 28-03-2018 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 374 382 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 319 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 382 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 442 454 3.0E-18 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07860 2b3abe9ec35a6cfacfeb24e3fa5e917c 480 Pfam PF00232 Glycosyl hydrolase family 1 2 477 2.3E-135 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS12425 2cfb521065ed194c4c1575866db53e91 86 Pfam PF03672 Uncharacterised protein family (UPF0154) 10 69 5.8E-28 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CPF12_RS12425 2cfb521065ed194c4c1575866db53e91 86 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 61 1.0E-10 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CPF12_RS12425 2cfb521065ed194c4c1575866db53e91 86 Hamap MF_00363 UPF0154 protein . 2 72 21.81 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CPF12_RS02260 6dd8bf67ca3c53ee3d4b0f5c927d425b 291 Gene3D G3DSA:3.40.50.300 1 259 4.4E-48 T 28-03-2018 CPF12_RS02260 6dd8bf67ca3c53ee3d4b0f5c927d425b 291 SMART SM00382 26 195 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02260 6dd8bf67ca3c53ee3d4b0f5c927d425b 291 Pfam PF00005 ABC transporter 18 147 3.7E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02260 6dd8bf67ca3c53ee3d4b0f5c927d425b 291 SUPERFAMILY SSF52540 2 211 1.87E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10305 2ec1ed198f1d5c8606d915b690029f1f 314 Pfam PF04198 Putative sugar-binding domain 63 311 9.9E-70 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CPF12_RS10305 2ec1ed198f1d5c8606d915b690029f1f 314 Gene3D G3DSA:3.40.50.1360 53 314 2.8E-43 T 28-03-2018 CPF12_RS10305 2ec1ed198f1d5c8606d915b690029f1f 314 Gene3D G3DSA:1.10.10.60 1 52 4.1E-17 T 28-03-2018 CPF12_RS10305 2ec1ed198f1d5c8606d915b690029f1f 314 SUPERFAMILY SSF100950 56 311 1.34E-69 T 28-03-2018 CPF12_RS10305 2ec1ed198f1d5c8606d915b690029f1f 314 SUPERFAMILY SSF88659 14 47 1.11E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS10305 2ec1ed198f1d5c8606d915b690029f1f 314 Pfam PF12802 MarR family 16 51 7.4E-7 T 28-03-2018 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 Pfam PF00347 Ribosomal protein L6 11 83 5.0E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 Pfam PF00347 Ribosomal protein L6 91 165 3.9E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 PIRSF PIRSF002162 1 178 9.8E-48 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 Gene3D G3DSA:3.90.930.12 2 83 7.8E-28 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 SUPERFAMILY SSF56053 84 178 7.77E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 Gene3D G3DSA:3.90.930.12 84 179 2.5E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 SUPERFAMILY SSF56053 1 83 8.38E-24 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.155 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS06135 c9e395b878146b9f0a0c8d7e01cf447d 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 2.5E-74 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 SUPERFAMILY SSF47917 347 462 7.32E-51 T 28-03-2018 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 SUPERFAMILY SSF50615 1 75 4.45E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 SMART SM00382 143 328 1.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 Gene3D G3DSA:2.40.10.170 1 75 1.7E-31 T 28-03-2018 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 73 2.4E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 344 3.4E-68 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 335 344 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 462 57.31 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 Gene3D G3DSA:3.40.50.300 76 349 1.5E-93 T 28-03-2018 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 Gene3D G3DSA:1.10.1140.10 350 460 7.9E-42 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 462 9.3E-255 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CPF12_RS06495 42cbb2739b188305b9383b1d959b0cba 466 SUPERFAMILY SSF52540 77 349 2.35E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Gene3D G3DSA:3.30.830.10 760 971 2.2E-27 T 28-03-2018 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Gene3D G3DSA:3.30.830.10 494 759 2.0E-23 T 28-03-2018 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 SUPERFAMILY SSF63411 524 765 6.46E-50 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 SUPERFAMILY SSF63411 784 971 2.1E-31 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Gene3D G3DSA:3.30.830.10 267 493 1.1E-20 T 28-03-2018 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 SUPERFAMILY SSF63411 10 244 2.33E-46 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Pfam PF08367 Peptidase M16C associated 466 715 3.1E-63 T 28-03-2018 IPR013578 Peptidase M16C associated GO:0006508 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Pfam PF05193 Peptidase M16 inactive domain 208 389 1.1E-13 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Gene3D G3DSA:3.30.830.10 33 257 9.3E-48 T 28-03-2018 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 SUPERFAMILY SSF63411 267 523 4.58E-54 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 SMART SM01264 465 715 9.1E-71 T 28-03-2018 IPR013578 Peptidase M16C associated GO:0006508 CPF12_RS02955 e70ef475c7dbf16c57941ff4d8aa9327 974 Pfam PF00675 Insulinase (Peptidase family M16) 60 157 1.2E-7 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 Pfam PF00367 phosphotransferase system, EIIB 8 41 2.8E-16 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 SUPERFAMILY SSF55604 6 79 1.83E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 618 6.4E-231 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 536 548 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 Pfam PF02378 Phosphotransferase system, EIIC 106 384 2.7E-34 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 474 594 1.8E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 Gene3D G3DSA:3.30.1360.60 4 80 6.6E-29 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 Gene3D G3DSA:2.70.70.10 461 619 2.5E-55 T 28-03-2018 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 SUPERFAMILY SSF51261 470 618 6.1E-53 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS04760 35a1ec25dafb607cf1e2c56f897fbd8b 619 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 473 597 3.3E-50 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS05165 d7b1705e4a4889cea72d66051f2d86eb 373 Pfam PF00155 Aminotransferase class I and II 52 360 9.5E-52 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS05165 d7b1705e4a4889cea72d66051f2d86eb 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 220 233 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CPF12_RS05165 d7b1705e4a4889cea72d66051f2d86eb 373 SUPERFAMILY SSF53383 43 370 8.46E-85 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS05165 d7b1705e4a4889cea72d66051f2d86eb 373 Gene3D G3DSA:3.40.640.10 40 253 1.4E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS05165 d7b1705e4a4889cea72d66051f2d86eb 373 Gene3D G3DSA:3.90.1150.10 254 373 6.6E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS03965 5e9ce418e523f8879bdc08b471a478dc 271 Pfam PF03180 NLPA lipoprotein 35 271 2.0E-82 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS03965 5e9ce418e523f8879bdc08b471a478dc 271 Gene3D G3DSA:3.40.190.10 131 271 3.5E-45 T 28-03-2018 CPF12_RS03965 5e9ce418e523f8879bdc08b471a478dc 271 SUPERFAMILY SSF53850 34 271 4.35E-79 T 28-03-2018 CPF12_RS03965 5e9ce418e523f8879bdc08b471a478dc 271 PIRSF PIRSF002854 1 271 9.1E-87 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS03965 5e9ce418e523f8879bdc08b471a478dc 271 Gene3D G3DSA:3.40.190.10 34 130 2.0E-21 T 28-03-2018 CPF12_RS03185 c1fa2efcfe2c62b0f5b9eebcc563ed98 269 PIRSF PIRSF004793 3 264 6.4E-93 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CPF12_RS03185 c1fa2efcfe2c62b0f5b9eebcc563ed98 269 SUPERFAMILY SSF143597 37 235 1.29E-69 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CPF12_RS03185 c1fa2efcfe2c62b0f5b9eebcc563ed98 269 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 7 252 5.7E-96 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CPF12_RS03185 c1fa2efcfe2c62b0f5b9eebcc563ed98 269 Gene3D G3DSA:3.40.1700.10 108 236 1.9E-37 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CPF12_RS03185 c1fa2efcfe2c62b0f5b9eebcc563ed98 269 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 115 233 2.7E-43 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CPF12_RS03185 c1fa2efcfe2c62b0f5b9eebcc563ed98 269 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 251 34.031 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 Pfam PF04962 KduI/IolB family 7 264 5.9E-103 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 Gene3D G3DSA:2.60.120.10 122 268 4.7E-59 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 Gene3D G3DSA:2.60.120.10 16 121 4.6E-27 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 18 264 4.8E-103 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 SUPERFAMILY SSF51182 15 253 1.91E-68 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 PIRSF PIRSF036628 2 268 1.8E-109 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CPF12_RS10970 b7259bad5ead623ee373c3a4b7f7e220 268 Hamap MF_01673 5-deoxy-glucuronate isomerase [iolB]. 3 267 56.716 T 28-03-2018 IPR023770 5-deoxy-glucuronate isomerase, Bacilli GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 SUPERFAMILY SSF46785 3 70 4.85E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 SMART SM00866 89 228 7.6E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 Gene3D G3DSA:3.40.1410.10 83 232 1.7E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 SUPERFAMILY SSF64288 82 231 4.24E-40 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 Pfam PF07702 UTRA domain 91 225 2.2E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 Gene3D G3DSA:1.10.10.10 2 67 6.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04735 0508efa3e1f3d5fd847c62a8d7831610 240 SMART SM00345 7 66 4.6E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS06360 a6be0e0ca19f4d88ac6c938532a350e6 114 Pfam PF06486 Protein of unknown function (DUF1093) 24 102 4.9E-19 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS06360 a6be0e0ca19f4d88ac6c938532a350e6 114 SUPERFAMILY SSF159121 19 114 6.54E-24 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS06360 a6be0e0ca19f4d88ac6c938532a350e6 114 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 7 110 4.6E-18 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 SUPERFAMILY SSF53335 5 176 2.43E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 SUPERFAMILY SSF53335 204 238 2.43E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 147 161 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 Gene3D G3DSA:3.40.50.150 10 237 4.9E-41 T 28-03-2018 CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 6 239 35.734 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 26 41 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 9 239 1.0E-95 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CPF12_RS09500 c37b2ffdfe679645e020b5fd4f5bbd0a 241 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 15 239 2.0E-78 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 538 6.0E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 SUPERFAMILY SSF52518 368 560 1.36E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 Gene3D G3DSA:3.40.50.970 2 193 9.1E-60 T 28-03-2018 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 10 560 5.7E-228 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 177 3.7E-57 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 427 446 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 Gene3D G3DSA:3.40.50.1220 194 347 9.6E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 332 8.3E-43 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 SUPERFAMILY SSF52518 9 180 2.1E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 SUPERFAMILY SSF52467 191 357 3.44E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS01945 fc3ee2b477eaff0a759f3314934dbbfe 565 Gene3D G3DSA:3.40.50.970 348 554 7.0E-50 T 28-03-2018 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SUPERFAMILY SSF54106 33 74 9.16E-11 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SUPERFAMILY SSF54106 414 459 3.66E-10 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SMART SM00257 416 460 9.3E-16 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SMART SM00257 277 321 3.0E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SMART SM00257 33 76 6.2E-13 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SMART SM00257 355 399 4.8E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SMART SM00047 108 264 2.3E-34 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Gene3D G3DSA:1.10.530.10 113 264 8.0E-33 T 28-03-2018 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 126 260 2.8E-19 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SUPERFAMILY SSF54106 276 320 1.83E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 SUPERFAMILY SSF54106 355 399 1.07E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Gene3D G3DSA:3.10.350.10 26 103 6.5E-16 T 28-03-2018 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Gene3D G3DSA:3.10.350.10 348 412 1.1E-16 T 28-03-2018 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Gene3D G3DSA:3.10.350.10 413 460 2.9E-15 T 28-03-2018 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Gene3D G3DSA:3.10.350.10 270 346 7.7E-14 T 28-03-2018 CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Pfam PF01476 LysM domain 417 459 8.1E-15 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Pfam PF01476 LysM domain 356 399 1.9E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Pfam PF01476 LysM domain 278 320 1.4E-13 T 28-03-2018 IPR018392 LysM domain CPF12_RS00845 2e725433459c60d422ab1e8689706ce0 460 Pfam PF01476 LysM domain 34 74 1.7E-12 T 28-03-2018 IPR018392 LysM domain CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Pfam PF06827 Zinc finger found in FPG and IleRS 885 913 9.5E-5 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Gene3D G3DSA:1.10.730.10 569 790 1.0E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Gene3D G3DSA:3.90.740.10 204 488 3.4E-94 T 28-03-2018 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 832 1.2E-302 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Gene3D G3DSA:3.30.2320.20 791 883 1.8E-24 T 28-03-2018 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 20.51 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 1.1E-216 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Gene3D G3DSA:3.40.50.620 41 203 2.1E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 Pfam PF08264 Anticodon-binding domain of tRNA 676 831 2.3E-29 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 SUPERFAMILY SSF52374 1 200 1.54E-149 T 28-03-2018 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 SUPERFAMILY SSF52374 392 639 1.54E-149 T 28-03-2018 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 SUPERFAMILY SSF50677 202 392 2.2E-59 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 2.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 2.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 2.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 2.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 2.5E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CPF12_RS01970 d837db4bccb27f97d5ec9554628516b6 926 SUPERFAMILY SSF47323 643 917 1.07E-76 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS04475 8934aaca60fe3383b00d500e637f8378 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 259 2.3E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS04475 8934aaca60fe3383b00d500e637f8378 268 Gene3D G3DSA:3.40.190.10 158 265 1.5E-13 T 28-03-2018 CPF12_RS04475 8934aaca60fe3383b00d500e637f8378 268 SUPERFAMILY SSF53850 33 262 8.26E-52 T 28-03-2018 CPF12_RS04475 8934aaca60fe3383b00d500e637f8378 268 Gene3D G3DSA:3.40.190.10 30 157 1.2E-29 T 28-03-2018 CPF12_RS04475 8934aaca60fe3383b00d500e637f8378 268 SMART SM00062 34 261 3.5E-68 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Pfam PF00623 RNA polymerase Rpb1, domain 2 378 474 4.9E-29 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 377 7.1E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.387 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 1.4E-87 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 SUPERFAMILY SSF64484 5 1182 0.0 T 28-03-2018 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1129 1.5E-63 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Gene3D G3DSA:2.40.50.100 910 1028 5.0E-41 T 28-03-2018 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Gene3D G3DSA:2.40.40.20 335 477 3.6E-39 T 28-03-2018 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 SMART SM00663 224 503 4.3E-184 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Pfam PF05000 RNA polymerase Rpb1, domain 4 693 759 1.0E-13 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS06025 3de9eb8776c1911c0835de6376bd32e7 1201 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 5.8E-35 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 184 5.8E-4 T 28-03-2018 CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 Pfam PF00106 short chain dehydrogenase 4 186 1.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.1E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.1E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.1E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 SUPERFAMILY SSF51735 3 250 4.28E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 Gene3D G3DSA:3.40.50.720 2 254 1.9E-54 T 28-03-2018 CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 7.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 7.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11070 9c1a1ba59a26cd510cf4ce55eb11ce73 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 7.7E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 Pfam PF00687 Ribosomal protein L1p/L10e family 37 220 3.0E-49 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 7.3E-101 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.563 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 PIRSF PIRSF002155 1 227 1.1E-74 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 Gene3D G3DSA:3.40.50.790 68 144 5.4E-37 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 SUPERFAMILY SSF56808 6 226 6.15E-81 T 28-03-2018 IPR023674 Ribosomal protein L1-like CPF12_RS06000 bf1a39aa13f1a9a0b92ba32b5dcbc71e 230 Gene3D G3DSA:3.30.190.20 145 224 2.4E-17 T 28-03-2018 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 Pfam PF02040 Arsenical pump membrane protein 5 427 2.9E-210 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 4 429 3.3E-220 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 325 347 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 219 244 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 366 391 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 399 423 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 179 202 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS01760 8227752da5f7f419b1f45c88a3ad10b0 430 PRINTS PR00758 Arsenical pump membrane protein signature 146 170 2.1E-107 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CPF12_RS07825 1628211332b6c6822208b26cb0ecc5ba 436 SUPERFAMILY SSF101960 15 434 3.27E-110 T 28-03-2018 CPF12_RS07825 1628211332b6c6822208b26cb0ecc5ba 436 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 425 3.3E-75 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CPF12_RS07825 1628211332b6c6822208b26cb0ecc5ba 436 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 409 1.6E-55 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 Gene3D G3DSA:2.40.10.10 96 224 6.7E-28 T 28-03-2018 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 Pfam PF13180 PDZ domain 335 434 4.7E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 Gene3D G3DSA:2.40.10.10 225 334 6.4E-33 T 28-03-2018 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 Gene3D G3DSA:2.30.42.10 335 441 1.9E-23 T 28-03-2018 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 PRINTS PR00834 HtrA/DegQ protease family signature 183 203 8.2E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 PRINTS PR00834 HtrA/DegQ protease family signature 381 393 8.2E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 PRINTS PR00834 HtrA/DegQ protease family signature 162 174 8.2E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 PRINTS PR00834 HtrA/DegQ protease family signature 290 307 8.2E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 PRINTS PR00834 HtrA/DegQ protease family signature 224 248 8.2E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 PRINTS PR00834 HtrA/DegQ protease family signature 268 285 8.2E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 SUPERFAMILY SSF50156 316 434 5.65E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 SMART SM00228 335 425 7.1E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 Pfam PF13365 Trypsin-like peptidase domain 150 297 6.7E-29 T 28-03-2018 CPF12_RS05015 0198f789b0b74cfb1596173ac758659a 442 SUPERFAMILY SSF50494 101 327 1.55E-54 T 28-03-2018 IPR009003 Peptidase S1, PA clan CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SUPERFAMILY SSF55785 241 359 6.11E-11 T 28-03-2018 IPR000014 PAS domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 591 1.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SMART SM00304 194 246 1.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SUPERFAMILY SSF47384 353 435 4.9E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SUPERFAMILY SSF158472 194 243 7.06E-8 T 28-03-2018 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Pfam PF16736 Single Cache-like 35 157 5.7E-11 T 28-03-2018 IPR031967 PhoR, single Cache-like domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Gene3D G3DSA:3.30.450.20 235 364 3.7E-17 T 28-03-2018 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Gene3D G3DSA:3.30.565.10 429 593 1.3E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Pfam PF00672 HAMP domain 194 242 4.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Gene3D G3DSA:1.10.287.130 365 428 2.4E-19 T 28-03-2018 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SMART SM00388 367 434 2.1E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Pfam PF13426 PAS domain 264 360 2.3E-8 T 28-03-2018 IPR000014 PAS domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 433 8.5E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SMART SM00387 479 593 1.1E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 Gene3D G3DSA:3.30.450.20 29 168 1.3E-24 T 28-03-2018 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 SUPERFAMILY SSF55874 423 592 2.62E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 546 7.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 7.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 7.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS06695 f52abe13448d6edd296f461fe912d680 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 7.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 5.6E-136 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 Pfam PF01018 GTP1/OBG 3 157 1.2E-55 T 28-03-2018 IPR006169 GTP1/OBG domain CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 Gene3D G3DSA:2.70.210.12 1 155 7.5E-55 T 28-03-2018 IPR006169 GTP1/OBG domain CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 SUPERFAMILY SSF82051 1 157 1.44E-51 T 28-03-2018 IPR006169 GTP1/OBG domain CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 SUPERFAMILY SSF52540 151 334 3.23E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 Pfam PF09269 Domain of unknown function (DUF1967) 357 425 1.4E-24 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.8E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.8E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.8E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.8E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 SUPERFAMILY SSF102741 355 427 5.23E-22 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 Gene3D G3DSA:3.40.50.300 158 333 1.8E-31 T 28-03-2018 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 357 426 5.8E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 Pfam PF01926 50S ribosome-binding GTPase 160 283 7.7E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 Hamap MF_01454 GTPase Obg [obg]. 1 329 45.974 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CPF12_RS00995 c571e79bc794e2fef0e06094d556952d 427 PIRSF PIRSF002401 1 375 1.0E-136 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 Gene3D G3DSA:1.10.1660.10 1 60 1.1E-20 T 28-03-2018 CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 SMART SM00422 6 75 1.5E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 SUPERFAMILY SSF46955 7 91 5.13E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 Gene3D G3DSA:1.10.1660.10 61 96 1.2E-4 T 28-03-2018 CPF12_RS11935 3b227ab9264be1cd2072d3b6b999244c 97 Pfam PF13411 MerR HTH family regulatory protein 7 74 1.5E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS00225 87826375cb9cd40c427ac87898f4328b 116 Pfam PF00936 BMC domain 45 99 1.1E-12 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00225 87826375cb9cd40c427ac87898f4328b 116 PIRSF PIRSF012296 1 116 1.1E-55 T 28-03-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 CPF12_RS00225 87826375cb9cd40c427ac87898f4328b 116 SMART SM00877 44 116 1.1E-17 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00225 87826375cb9cd40c427ac87898f4328b 116 SUPERFAMILY SSF143414 43 106 7.06E-14 T 28-03-2018 CPF12_RS06125 3b68cdc96087c6175e49d287db7411eb 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06125 3b68cdc96087c6175e49d287db7411eb 61 Gene3D G3DSA:4.10.830.10 1 61 2.0E-21 T 28-03-2018 CPF12_RS06125 3b68cdc96087c6175e49d287db7411eb 61 SUPERFAMILY SSF57716 4 61 8.55E-22 T 28-03-2018 CPF12_RS06125 3b68cdc96087c6175e49d287db7411eb 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.265 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CPF12_RS06125 3b68cdc96087c6175e49d287db7411eb 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.5E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS00660 285de215387fd0290e3a950863b11a90 232 Pfam PF00005 ABC transporter 22 174 4.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00660 285de215387fd0290e3a950863b11a90 232 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00660 285de215387fd0290e3a950863b11a90 232 Gene3D G3DSA:3.40.50.300 1 232 4.1E-62 T 28-03-2018 CPF12_RS00660 285de215387fd0290e3a950863b11a90 232 SUPERFAMILY SSF52540 4 228 3.97E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00660 285de215387fd0290e3a950863b11a90 232 SMART SM00382 31 223 2.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS01995 36a34bfd75a1ae5193981e1142fa2093 224 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 221 1.1E-49 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CPF12_RS01995 36a34bfd75a1ae5193981e1142fa2093 224 PIRSF PIRSF004848 1 223 2.8E-63 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CPF12_RS01995 36a34bfd75a1ae5193981e1142fa2093 224 SUPERFAMILY SSF51419 1 220 4.22E-68 T 28-03-2018 IPR029066 PLP-binding barrel CPF12_RS01995 36a34bfd75a1ae5193981e1142fa2093 224 Pfam PF01168 Alanine racemase, N-terminal domain 8 220 4.9E-18 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CPF12_RS01995 36a34bfd75a1ae5193981e1142fa2093 224 Gene3D G3DSA:3.20.20.10 1 223 1.3E-48 T 28-03-2018 IPR029066 PLP-binding barrel CPF12_RS01995 36a34bfd75a1ae5193981e1142fa2093 224 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 Gene3D G3DSA:3.40.50.2300 78 187 1.7E-12 T 28-03-2018 CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 2.9E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 Pfam PF13377 Periplasmic binding protein-like domain 189 351 1.9E-34 T 28-03-2018 CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 SUPERFAMILY SSF53822 133 351 2.14E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 SUPERFAMILY SSF46785 3 72 6.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 Gene3D G3DSA:1.10.10.10 1 70 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 SMART SM00345 9 68 4.0E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 Gene3D G3DSA:3.40.50.2300 188 353 4.3E-40 T 28-03-2018 CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 8.3E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS00315 a01d9d0dad440ce8b53990d9b3dafaab 357 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 8.3E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Gene3D G3DSA:3.40.50.300 415 615 3.3E-23 T 28-03-2018 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Pfam PF00005 ABC transporter 622 858 1.5E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 SUPERFAMILY SSF52540 7 206 8.89E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 SUPERFAMILY SSF52540 430 569 8.89E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Gene3D G3DSA:3.40.50.300 616 951 1.9E-56 T 28-03-2018 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Gene3D G3DSA:1.10.8.280 284 405 1.0E-35 T 28-03-2018 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 922 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Gene3D G3DSA:3.40.50.300 37 138 2.0E-4 T 28-03-2018 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 SUPERFAMILY SSF52540 614 911 2.92E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Gene3D G3DSA:3.40.50.300 2 36 0.0019 T 28-03-2018 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Gene3D G3DSA:3.30.190.20 139 247 1.5E-42 T 28-03-2018 CPF12_RS06745 4d177722f037954b26e3eb1ad6aead50 955 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 22.822 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 Gene3D G3DSA:3.40.50.1440 9 214 4.0E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 SMART SM00864 13 205 1.2E-117 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 SUPERFAMILY SSF55307 204 317 1.47E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 330 1.0E-138 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.4E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.4E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.4E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.4E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 SMART SM00865 207 324 1.0E-54 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 1.0E-44 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 Gene3D G3DSA:3.30.1330.20 215 324 4.0E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 Pfam PF12327 FtsZ family, C-terminal domain 222 315 2.0E-33 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 359 39.343 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CPF12_RS02000 e75adc31b91bab5b3c17c34f18e54c77 376 SUPERFAMILY SSF52490 12 208 5.49E-73 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 SMART SM01016 9 95 2.5E-35 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 SUPERFAMILY SSF55190 11 115 4.19E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Gene3D G3DSA:1.10.730.10 404 558 2.5E-48 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Gene3D G3DSA:3.30.1360.70 3 108 4.9E-33 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 SUPERFAMILY SSF47323 432 558 7.19E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Pfam PF00750 tRNA synthetases class I (R) 104 400 9.0E-27 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 11 558 5.2E-158 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 SMART SM00836 438 558 1.2E-53 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 8.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 307 328 8.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 8.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 8.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 95 2.3E-25 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 558 27.228 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 SUPERFAMILY SSF52374 118 448 2.82E-92 T 28-03-2018 CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Gene3D G3DSA:3.40.50.620 109 369 2.8E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS06400 0eaad055b32df7bcdb617cfa297b4a57 558 Pfam PF05746 DALR anticodon binding domain 438 558 4.4E-36 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 SUPERFAMILY SSF82866 644 861 8.89E-35 T 28-03-2018 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 SUPERFAMILY SSF82866 269 489 4.19E-33 T 28-03-2018 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 Gene3D G3DSA:1.20.1640.10 637 861 1.2E-36 T 28-03-2018 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 Gene3D G3DSA:1.20.1640.10 276 497 5.2E-33 T 28-03-2018 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 Pfam PF03176 MMPL family 225 476 3.0E-23 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 Pfam PF03176 MMPL family 625 858 2.2E-30 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CPF12_RS04450 22aaaf77d3b9b567a3a8a487be4250bc 861 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 275 857 4.8E-119 T 28-03-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 Gene3D G3DSA:2.30.40.10 3 70 3.2E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 PIRSF PIRSF038994 1 379 5.2E-120 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 SUPERFAMILY SSF51338 3 56 9.55E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 SUPERFAMILY SSF51338 347 379 9.55E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 369 1.4E-97 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 SUPERFAMILY SSF51556 57 345 6.12E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 Gene3D G3DSA:3.20.20.140 71 347 1.0E-99 T 28-03-2018 CPF12_RS10940 591bcb841c995978c1a50f78eb9727c3 381 Pfam PF01979 Amidohydrolase family 54 362 3.8E-25 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CPF12_RS06170 c22f95bf08c633c028f12baead9b0b12 72 SMART SM00316 4 72 3.9E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS06170 c22f95bf08c633c028f12baead9b0b12 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.5E-27 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CPF12_RS06170 c22f95bf08c633c028f12baead9b0b12 72 SUPERFAMILY SSF50249 1 71 5.88E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS06170 c22f95bf08c633c028f12baead9b0b12 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.8E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CPF12_RS06170 c22f95bf08c633c028f12baead9b0b12 72 Gene3D G3DSA:2.40.50.140 1 72 2.7E-37 T 28-03-2018 CPF12_RS06170 c22f95bf08c633c028f12baead9b0b12 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.637 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CPF12_RS12325 cb5fc12e6b3fbee2124fac235068fec5 255 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 252 40.044 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CPF12_RS12325 cb5fc12e6b3fbee2124fac235068fec5 255 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 251 1.0E-83 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CPF12_RS12325 cb5fc12e6b3fbee2124fac235068fec5 255 Gene3D G3DSA:3.40.1180.10 10 254 1.0E-97 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CPF12_RS12325 cb5fc12e6b3fbee2124fac235068fec5 255 SUPERFAMILY SSF64005 19 246 1.44E-91 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CPF12_RS12325 cb5fc12e6b3fbee2124fac235068fec5 255 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 197 214 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CPF12_RS12325 cb5fc12e6b3fbee2124fac235068fec5 255 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 251 2.1E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 Gene3D G3DSA:3.30.1360.40 74 146 1.0E-23 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 5.9E-21 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 5.9E-21 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 5.9E-21 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 5.9E-21 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 62.845 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 SUPERFAMILY SSF55252 80 149 3.4E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 5.4E-46 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 Gene3D G3DSA:1.10.10.10 3 66 7.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 142 9.4E-21 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 69 3.7E-26 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 SUPERFAMILY SSF46785 3 78 9.72E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09245 eac19c88102b9b5431a70836ec99f5ac 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 149 7.0E-11 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 Gene3D G3DSA:3.40.630.30 1 147 6.9E-12 T 28-03-2018 CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 Pfam PF13530 Sterol carrier protein domain 189 401 2.0E-55 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 SUPERFAMILY SSF55729 11 298 1.03E-79 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 Gene3D G3DSA:3.30.1050.10 292 400 8.6E-28 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 Pfam PF13527 Acetyltransferase (GNAT) domain 12 145 1.1E-41 T 28-03-2018 CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 Gene3D G3DSA:3.40.630.30 148 291 4.8E-41 T 28-03-2018 CPF12_RS07040 c38697b236da7390d66d834b1bcc4f8b 406 SUPERFAMILY SSF55718 299 406 5.1E-27 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.338 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 3.4E-47 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-18 T 28-03-2018 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 Gene3D G3DSA:1.10.1900.20 55 116 1.1E-26 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 Pfam PF00453 Ribosomal protein L20 3 109 6.6E-46 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.2E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.2E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.2E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02505 556df47aee57f315a53883d0c609582d 119 SUPERFAMILY SSF74731 2 114 5.1E-47 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS00240 80e145a3399866caaad2f2c67a33789d 147 PIRSF PIRSF036409 1 147 4.7E-58 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CPF12_RS00240 80e145a3399866caaad2f2c67a33789d 147 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 142 7.8E-57 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CPF12_RS00240 80e145a3399866caaad2f2c67a33789d 147 SUPERFAMILY SSF52540 3 139 2.7E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00240 80e145a3399866caaad2f2c67a33789d 147 Gene3D G3DSA:3.40.50.300 1 147 7.1E-16 T 28-03-2018 CPF12_RS00240 80e145a3399866caaad2f2c67a33789d 147 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 2 143 2.4E-56 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CPF12_RS04710 df6410b844306b3b0e0b64722aae0631 469 Pfam PF00916 Sulfate permease family 162 355 1.1E-21 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CPF12_RS04710 df6410b844306b3b0e0b64722aae0631 469 Pfam PF00916 Sulfate permease family 15 144 1.5E-19 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CPF12_RS04710 df6410b844306b3b0e0b64722aae0631 469 SUPERFAMILY SSF52091 392 457 1.26E-5 T 28-03-2018 IPR002645 STAS domain CPF12_RS04710 df6410b844306b3b0e0b64722aae0631 469 Gene3D G3DSA:3.30.750.24 385 465 8.5E-4 T 28-03-2018 IPR002645 STAS domain CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 SUPERFAMILY SSF53448 5 307 7.21E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.668 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Gene3D G3DSA:2.160.10.10 321 440 4.2E-33 T 28-03-2018 CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Pfam PF00483 Nucleotidyl transferase 6 220 8.2E-25 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 299 1.6E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 6.7E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 351 8.7E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 SUPERFAMILY SSF51161 249 450 1.7E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 1.1E-182 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Gene3D G3DSA:2.160.10.10 241 320 8.6E-15 T 28-03-2018 CPF12_RS05750 318284d984246144a6bf44aa6ceab97a 458 Gene3D G3DSA:3.90.550.10 1 240 8.6E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS01290 4d5817fbc93d7a5470c9b9cf3f2136c0 916 SUPERFAMILY SSF51261 714 911 2.46E-37 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS01290 4d5817fbc93d7a5470c9b9cf3f2136c0 916 Pfam PF01551 Peptidase family M23 808 896 4.3E-25 T 28-03-2018 IPR016047 Peptidase M23 CPF12_RS01290 4d5817fbc93d7a5470c9b9cf3f2136c0 916 Pfam PF06605 Prophage endopeptidase tail 93 338 4.2E-10 T 28-03-2018 IPR010572 Prophage tail endopeptidase CPF12_RS01290 4d5817fbc93d7a5470c9b9cf3f2136c0 916 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 29 346 2.6E-28 T 28-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CPF12_RS01290 4d5817fbc93d7a5470c9b9cf3f2136c0 916 Gene3D G3DSA:2.70.70.10 750 916 2.7E-35 T 28-03-2018 CPF12_RS00775 17f54ba2cf60332abdeab10fc5eca09b 669 Pfam PF12146 Serine aminopeptidase, S33 158 244 1.8E-7 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CPF12_RS00775 17f54ba2cf60332abdeab10fc5eca09b 669 Gene3D G3DSA:3.40.50.1820 121 398 1.6E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS00775 17f54ba2cf60332abdeab10fc5eca09b 669 Gene3D G3DSA:2.60.40.1310 556 669 2.0E-4 T 28-03-2018 CPF12_RS00775 17f54ba2cf60332abdeab10fc5eca09b 669 SUPERFAMILY SSF53474 143 268 2.1E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS00775 17f54ba2cf60332abdeab10fc5eca09b 669 SUPERFAMILY SSF53474 322 391 2.1E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08985 01576bdff158bdfc5c68947008086e4f 362 Gene3D G3DSA:3.40.50.1970 5 162 2.4E-24 T 28-03-2018 CPF12_RS08985 01576bdff158bdfc5c68947008086e4f 362 SUPERFAMILY SSF56796 10 357 5.1E-61 T 28-03-2018 CPF12_RS08985 01576bdff158bdfc5c68947008086e4f 362 Gene3D G3DSA:1.20.1090.10 163 362 1.3E-26 T 28-03-2018 CPF12_RS08985 01576bdff158bdfc5c68947008086e4f 362 PIRSF PIRSF000112 1 361 4.5E-105 T 28-03-2018 CPF12_RS08985 01576bdff158bdfc5c68947008086e4f 362 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 152 180 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CPF12_RS08985 01576bdff158bdfc5c68947008086e4f 362 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 348 8.6E-51 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CPF12_RS00090 ca5d40be9b50ed9a0be19e19bed00535 241 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 232 2.4E-81 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CPF12_RS00090 ca5d40be9b50ed9a0be19e19bed00535 241 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 236 36.186 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CPF12_RS00090 ca5d40be9b50ed9a0be19e19bed00535 241 Gene3D G3DSA:3.20.20.70 2 240 6.3E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS00090 ca5d40be9b50ed9a0be19e19bed00535 241 Pfam PF00977 Histidine biosynthesis protein 3 229 1.9E-78 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CPF12_RS00090 ca5d40be9b50ed9a0be19e19bed00535 241 SUPERFAMILY SSF51366 1 235 1.68E-70 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS12110 253bd93bbbbcc44c13fba1cb735faa41 188 Gene3D G3DSA:1.10.340.30 1 183 8.5E-66 T 28-03-2018 CPF12_RS12110 253bd93bbbbcc44c13fba1cb735faa41 188 Pfam PF03352 Methyladenine glycosylase 6 182 3.5E-63 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CPF12_RS12110 253bd93bbbbcc44c13fba1cb735faa41 188 SUPERFAMILY SSF48150 2 184 7.85E-62 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 SMART SM00327 337 580 1.5E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Pfam PF13519 von Willebrand factor type A domain 340 462 3.7E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 SUPERFAMILY SSF53300 514 550 1.25E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 SUPERFAMILY SSF53300 335 465 1.25E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Gene3D G3DSA:3.40.50.410 330 596 5.5E-30 T 28-03-2018 IPR002035 von Willebrand factor, type A CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Gene3D G3DSA:2.60.40.810 1040 1180 3.5E-16 T 28-03-2018 CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Gene3D G3DSA:2.60.40.810 924 1039 4.7E-15 T 28-03-2018 CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 SUPERFAMILY SSF49478 702 730 7.46E-7 T 28-03-2018 CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 SUPERFAMILY SSF49478 767 814 7.46E-7 T 28-03-2018 CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Pfam PF00746 LPXTG cell wall anchor motif 1176 1217 2.9E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Gene3D G3DSA:2.60.40.1140 701 828 7.9E-9 T 28-03-2018 CPF12_RS03545 607b1470efcfadd41699a3b5e1bb86c5 1219 Gene3D G3DSA:2.60.40.10 829 923 5.4E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 Gene3D G3DSA:3.40.1190.10 3 295 2.1E-79 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 SUPERFAMILY SSF53244 296 426 6.41E-22 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 425 5.9E-124 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 Pfam PF08245 Mur ligase middle domain 46 269 1.7E-11 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 Pfam PF02875 Mur ligase family, glutamate ligase domain 294 371 2.0E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 Gene3D G3DSA:3.90.190.20 296 431 4.3E-22 T 28-03-2018 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 PIRSF PIRSF001563 1 431 1.8E-144 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CPF12_RS01120 fcfce81235e096975ec237c1c9a9d971 435 SUPERFAMILY SSF53623 3 294 7.73E-92 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.740 554 699 5.2E-18 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.740 120 263 3.9E-8 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.740 1 119 3.2E-13 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.740 406 549 2.9E-13 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1750 1813 2.9E-6 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1186 1250 2.51E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1082 1177 4.8E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1832 1925 1.2E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.810 2206 2303 2.9E-22 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.810 1178 1268 1.3E-19 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.810 1545 1643 6.0E-21 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 813 877 2.79E-6 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1001 1068 4.71E-8 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 2219 2284 3.92E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 718 774 3.92E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1843 1908 6.28E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49401 121 253 1.81E-10 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49401 271 393 1.99E-14 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49401 2 114 3.73E-14 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 2125 2190 3.92E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1089 1158 4.71E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1373 1434 1.41E-6 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49401 407 552 8.7E-17 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1655 1717 2.2E-8 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1559 1626 9.81E-8 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 2031 2096 3.26E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 2314 2378 3.3E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.740 264 405 2.5E-13 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49401 556 692 2.73E-21 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 804 892 4.6E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 990 1081 5.5E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 707 803 3.5E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1738 1831 4.6E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 893 989 1.7E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1456 1544 2.6E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1269 1362 2.3E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 2304 2399 2.6E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 2115 2205 4.6E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 2400 2487 1.4E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1926 2020 2.3E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1644 1737 4.8E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 2021 2114 2.3E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Gene3D G3DSA:2.60.40.10 1363 1455 2.3E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 2404 2467 2.51E-5 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1937 2002 2.9E-7 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1467 1532 7.45E-8 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 SUPERFAMILY SSF49478 1279 1342 3.22E-9 T 28-03-2018 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Pfam PF05737 Collagen binding domain 2 103 5.4E-15 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Pfam PF05737 Collagen binding domain 409 540 1.4E-9 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Pfam PF05737 Collagen binding domain 138 231 1.3E-6 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 CPF12_RS05250 3b0f0baf3254ac03217e572b7d923c8f 2591 Pfam PF05737 Collagen binding domain 560 688 8.6E-14 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 Gene3D G3DSA:3.40.50.300 245 495 1.9E-35 T 28-03-2018 CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 SMART SM00382 23 211 1.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 SUPERFAMILY SSF52540 3 219 9.63E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 Pfam PF00005 ABC transporter 269 424 1.9E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 Pfam PF00005 ABC transporter 15 163 1.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 SUPERFAMILY SSF52540 250 484 1.81E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00955 cfdb1d3b1b1de62c5db5b04bb4c71094 500 Gene3D G3DSA:3.40.50.300 1 244 4.6E-49 T 28-03-2018 CPF12_RS08750 ebb0fb3b25cbdc01463487749da124aa 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 6.8E-23 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CPF12_RS08750 ebb0fb3b25cbdc01463487749da124aa 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.3E-34 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CPF12_RS08750 ebb0fb3b25cbdc01463487749da124aa 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.88 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CPF12_RS08750 ebb0fb3b25cbdc01463487749da124aa 96 SUPERFAMILY SSF141000 4 94 1.7E-31 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 Pfam PF00005 ABC transporter 267 420 9.9E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 Pfam PF00005 ABC transporter 18 167 9.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 Gene3D G3DSA:3.40.50.300 1 233 1.2E-52 T 28-03-2018 CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 SUPERFAMILY SSF52540 3 218 3.22E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 SMART SM00382 275 469 1.9E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 SMART SM00382 27 216 3.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 Gene3D G3DSA:3.40.50.300 253 489 4.7E-36 T 28-03-2018 CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 SUPERFAMILY SSF52540 238 479 5.43E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01700 b4b50ba1a36b1ff357413dbd6a812ac4 492 ProSitePatterns PS00211 ABC transporters family signature. 393 407 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Pfam PF01571 Aminomethyltransferase folate-binding domain 14 258 2.4E-90 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 SUPERFAMILY SSF103025 3 281 6.44E-96 T 28-03-2018 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 352 8.7E-22 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 360 3.0E-130 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 361 45.657 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 PIRSF PIRSF006487 1 363 1.2E-95 T 28-03-2018 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Gene3D G3DSA:3.30.1360.120 134 235 1.1E-24 T 28-03-2018 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Gene3D G3DSA:3.30.1360.120 4 133 2.1E-32 T 28-03-2018 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Gene3D G3DSA:4.10.1250.10 237 279 1.5E-15 T 28-03-2018 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 Gene3D G3DSA:2.40.30.110 281 363 5.0E-22 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CPF12_RS01575 1a71a87320727d07a36f68b4870c3a93 363 SUPERFAMILY SSF101790 273 361 1.37E-21 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 Pfam PF00664 ABC transporter transmembrane region 16 285 2.8E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 SUPERFAMILY SSF90123 4 319 3.4E-75 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 Pfam PF00005 ABC transporter 349 495 2.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 Gene3D G3DSA:3.40.50.300 316 573 2.9E-65 T 28-03-2018 CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 SUPERFAMILY SSF52540 324 567 8.05E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 Gene3D G3DSA:1.20.1560.10 1 315 2.6E-75 T 28-03-2018 CPF12_RS03350 75150e2eb27a3540c952c46d8008aa89 574 SMART SM00382 357 543 3.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 SMART SM00448 3 114 1.1E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 SUPERFAMILY SSF52172 6 180 1.99E-38 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 Gene3D G3DSA:3.40.50.2300 2 125 5.7E-33 T 28-03-2018 CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 225 2.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 SMART SM00862 147 225 1.6E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 Gene3D G3DSA:1.10.10.10 126 229 1.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11740 a3c978d19e10fb8b4c3c23bf60e9a2cf 229 Pfam PF00072 Response regulator receiver domain 6 114 1.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 42 49 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 293 36.685 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 289 1.2E-19 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 126 137 1.3E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 42 61 1.3E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 244 253 1.3E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 279 1.3E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 SUPERFAMILY SSF53671 2 292 2.75E-84 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 139 1.2E-34 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 Gene3D G3DSA:3.40.50.1370 140 295 9.6E-46 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 32 54 2.6E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 125 142 2.6E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 2.6E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 248 253 2.6E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 70 79 2.6E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 272 286 2.6E-28 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 290 3.2E-83 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11320 b8696ff6a3df5006151c2d1777f1d1ea 297 Gene3D G3DSA:3.40.50.1370 1 139 9.7E-43 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS08945 1e5865e23c7a66f676225a08be702877 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 123 137 3.0E-7 T 28-03-2018 CPF12_RS08945 1e5865e23c7a66f676225a08be702877 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 220 244 3.0E-7 T 28-03-2018 CPF12_RS08945 1e5865e23c7a66f676225a08be702877 330 Gene3D G3DSA:3.40.50.150 89 330 7.7E-35 T 28-03-2018 CPF12_RS08945 1e5865e23c7a66f676225a08be702877 330 Pfam PF02384 N-6 DNA Methylase 95 314 3.2E-18 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CPF12_RS08945 1e5865e23c7a66f676225a08be702877 330 PIRSF PIRSF026567 2 330 9.8E-122 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CPF12_RS08945 1e5865e23c7a66f676225a08be702877 330 SUPERFAMILY SSF53335 9 320 1.09E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS05010 5f5ba76921788ae865c89863426d2727 126 Pfam PF08818 Domain of unknown function (DU1801) 19 111 1.0E-15 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CPF12_RS05010 5f5ba76921788ae865c89863426d2727 126 SUPERFAMILY SSF159888 5 114 1.31E-28 T 28-03-2018 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 SUPERFAMILY SSF53383 5 391 3.99E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 Gene3D G3DSA:3.40.640.10 104 278 8.0E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 199 222 5.1E-18 T 28-03-2018 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 116 137 5.1E-18 T 28-03-2018 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 163 187 5.1E-18 T 28-03-2018 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 94 114 5.1E-18 T 28-03-2018 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 230 254 5.1E-18 T 28-03-2018 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 Pfam PF00155 Aminotransferase class I and II 33 386 7.7E-74 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 Gene3D G3DSA:3.90.1150.10 279 395 8.2E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS10335 2fb7aa117aa13d7764bdd53719e5d59b 396 Gene3D G3DSA:3.90.1150.10 1 103 7.5E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 SUPERFAMILY SSF52283 2 138 1.34E-28 T 28-03-2018 CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 320 6.9E-26 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 SUPERFAMILY SSF51735 104 290 1.02E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 199 221 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 Gene3D G3DSA:3.40.50.720 1 116 9.3E-29 T 28-03-2018 CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 289 1.1E-55 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CPF12_RS11750 5a02c891b560115504664ff09b57e8c6 321 Gene3D G3DSA:3.40.50.720 117 292 5.4E-51 T 28-03-2018 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Pfam PF00905 Penicillin binding protein transpeptidase domain 363 662 3.1E-61 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 SUPERFAMILY SSF56519 164 345 1.01E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Gene3D G3DSA:3.30.1390.30 188 242 1.7E-11 T 28-03-2018 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Gene3D G3DSA:3.10.450.100 39 154 2.3E-21 T 28-03-2018 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Gene3D G3DSA:3.90.1310.10 243 344 4.5E-22 T 28-03-2018 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Pfam PF03717 Penicillin-binding Protein dimerisation domain 166 323 4.7E-27 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 SUPERFAMILY SSF54427 44 156 4.12E-19 T 28-03-2018 IPR032710 NTF2-like domain CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Gene3D G3DSA:3.40.710.10 345 679 3.5E-54 T 28-03-2018 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 43 159 6.0E-22 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CPF12_RS02645 8c1388d02cc386b1bbe20eddde662893 679 SUPERFAMILY SSF56601 346 678 4.54E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 Pfam PF01479 S4 domain 5 47 2.6E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 Gene3D G3DSA:3.40.50.150 64 274 9.8E-59 T 28-03-2018 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 SUPERFAMILY SSF53335 55 246 2.41E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 SMART SM00363 5 70 1.4E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 Gene3D G3DSA:3.10.290.10 3 62 2.3E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 Pfam PF01728 FtsJ-like methyltransferase 61 243 7.1E-19 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 PIRSF PIRSF005578 1 263 1.8E-101 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 238 1.7E-90 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CPF12_RS09240 6505a725b543e03f42f9b27d297b987d 274 SUPERFAMILY SSF55174 4 70 6.18E-12 T 28-03-2018 CPF12_RS00040 e8e067e5ee019506d0bf1ee985d9e038 729 Pfam PF09397 Ftsk gamma domain 660 720 3.7E-29 T 28-03-2018 IPR018541 FtsK gamma domain CPF12_RS00040 e8e067e5ee019506d0bf1ee985d9e038 729 SUPERFAMILY SSF46785 659 722 6.26E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00040 e8e067e5ee019506d0bf1ee985d9e038 729 Pfam PF01580 FtsK/SpoIIIE family 367 563 1.8E-62 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CPF12_RS00040 e8e067e5ee019506d0bf1ee985d9e038 729 Gene3D G3DSA:3.40.50.300 155 691 6.8E-55 T 28-03-2018 CPF12_RS00040 e8e067e5ee019506d0bf1ee985d9e038 729 SUPERFAMILY SSF52540 341 634 2.3E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00040 e8e067e5ee019506d0bf1ee985d9e038 729 SMART SM00843 658 723 5.5E-36 T 28-03-2018 IPR018541 FtsK gamma domain CPF12_RS01900 aeed84ba873d22bf7d03f3d5f5853d06 115 Pfam PF11337 Protein of unknown function (DUF3139) 1 76 1.6E-14 T 28-03-2018 IPR021486 Protein of unknown function DUF3139 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 510 566 1.7E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 SUPERFAMILY SSF53738 30 188 1.06E-42 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 212 321 2.9E-21 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 180 1.6E-40 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Gene3D G3DSA:3.40.120.10 15 214 2.9E-52 T 28-03-2018 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 328 451 3.4E-19 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 SUPERFAMILY SSF55957 476 569 4.84E-16 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 SUPERFAMILY SSF53738 211 318 3.92E-18 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Gene3D G3DSA:3.40.120.10 215 339 3.3E-29 T 28-03-2018 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 251 2.6E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 2.6E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 299 314 2.6E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Gene3D G3DSA:3.30.310.50 475 576 2.6E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 Gene3D G3DSA:3.40.120.10 340 458 2.0E-32 T 28-03-2018 CPF12_RS00860 aeff897e1b879d733c34f875ec8c1af9 576 SUPERFAMILY SSF53738 307 457 1.02E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03865 53b3cdd6e5c415e663acd65b708b7f8a 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 9.0E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS03865 53b3cdd6e5c415e663acd65b708b7f8a 129 Gene3D G3DSA:3.10.180.10 2 129 3.7E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03865 53b3cdd6e5c415e663acd65b708b7f8a 129 SUPERFAMILY SSF54593 3 127 7.52E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03865 53b3cdd6e5c415e663acd65b708b7f8a 129 ProSitePatterns PS00935 Glyoxalase I signature 2. 72 84 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 SUPERFAMILY SSF53223 4 260 5.11E-89 T 28-03-2018 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 Pfam PF00390 Malic enzyme, N-terminal domain 68 251 2.6E-64 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 Gene3D G3DSA:3.40.50.720 259 543 1.9E-90 T 28-03-2018 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 Pfam PF03949 Malic enzyme, NAD binding domain 261 517 4.7E-90 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 137 166 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 173 195 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 232 250 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 395 411 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 257 273 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 288 304 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PRINTS PR00072 Malic enzyme signature 73 97 3.2E-65 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 SMART SM01274 67 251 2.9E-79 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 PIRSF PIRSF000106 1 543 2.8E-195 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 Gene3D G3DSA:3.40.50.10380 1 258 5.0E-92 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 SMART SM00919 261 517 5.2E-96 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CPF12_RS01525 013f83e82f4e92870bc5ffd0f0495475 543 SUPERFAMILY SSF51735 261 542 5.58E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 Gene3D G3DSA:3.50.7.10 192 371 9.7E-96 T 28-03-2018 IPR027409 GroEL-like apical domain CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 522 1.4E-248 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 SUPERFAMILY SSF52029 183 374 5.38E-82 T 28-03-2018 IPR027409 GroEL-like apical domain CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 521 3.1E-105 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 SUPERFAMILY SSF54849 137 204 1.85E-24 T 28-03-2018 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 Gene3D G3DSA:1.10.560.10 372 513 2.0E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 40.964 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 PRINTS PR00298 60kDa chaperonin signature 266 289 3.2E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 PRINTS PR00298 60kDa chaperonin signature 396 417 3.2E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 PRINTS PR00298 60kDa chaperonin signature 26 52 3.2E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 PRINTS PR00298 60kDa chaperonin signature 82 109 3.2E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 PRINTS PR00298 60kDa chaperonin signature 348 373 3.2E-72 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 SUPERFAMILY SSF48592 6 133 1.22E-77 T 28-03-2018 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 SUPERFAMILY SSF48592 404 518 1.22E-77 T 28-03-2018 CPF12_RS09150 d485b7f6ca2d3b09b6578fe36ac6ed1a 542 Gene3D G3DSA:1.10.560.10 1 191 1.4E-34 T 28-03-2018 IPR027413 GroEL-like equatorial domain CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 Gene3D G3DSA:1.20.5.710 3 49 9.3E-15 T 28-03-2018 CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 54 120 2.5E-27 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 Gene3D G3DSA:3.30.1390.10 50 120 4.1E-28 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 55 93 3.0E-7 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 120 23.869 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 120 2.4E-44 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 SUPERFAMILY SSF54736 49 120 4.01E-23 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 49 8.4E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06010 867829cb52cc4f8b90e03287ddd52d86 120 SUPERFAMILY SSF48300 4 56 7.06E-15 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 SMART SM00387 780 893 1.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Pfam PF00512 His Kinase A (phospho-acceptor) domain 668 736 5.3E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Gene3D G3DSA:1.10.287.130 659 730 6.2E-12 T 28-03-2018 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Gene3D G3DSA:1.20.120.620 397 497 5.5E-21 T 28-03-2018 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 SMART SM00388 668 736 2.7E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 SUPERFAMILY SSF47384 663 737 6.87E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 877 890 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 853 871 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 816 830 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 SUPERFAMILY SSF55781 508 664 6.13E-7 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 24 231 2.2E-86 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Gene3D G3DSA:3.30.565.10 731 893 1.8E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Gene3D G3DSA:3.30.450.40 498 658 1.2E-9 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 783 891 2.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Gene3D G3DSA:3.40.50.620 245 375 5.6E-6 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Pfam PF13493 Domain of unknown function (DUF4118) 401 505 1.9E-26 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 SUPERFAMILY SSF55874 725 891 3.67E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS10665 66a36374f08f9a37c6c9e23608a9d3c6 895 Gene3D G3DSA:3.40.50.300 23 151 1.2E-19 T 28-03-2018 CPF12_RS02490 1844581c9317b8b0b696ebaef2e590ca 715 Gene3D G3DSA:2.60.40.1280 29 191 2.7E-21 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CPF12_RS02490 1844581c9317b8b0b696ebaef2e590ca 715 Pfam PF05737 Collagen binding domain 176 298 4.4E-21 T 28-03-2018 IPR008456 Collagen binding domain GO:0005518 CPF12_RS02490 1844581c9317b8b0b696ebaef2e590ca 715 SUPERFAMILY SSF49401 175 308 3.23E-18 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS02490 1844581c9317b8b0b696ebaef2e590ca 715 SUPERFAMILY SSF49401 34 162 1.74E-19 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 SUPERFAMILY SSF50447 154 303 6.13E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Gene3D G3DSA:3.40.50.300 1 69 2.0E-9 T 28-03-2018 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 SUPERFAMILY SSF52540 3 210 1.13E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Gene3D G3DSA:3.30.70.870 306 404 9.4E-34 T 28-03-2018 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Pfam PF00679 Elongation factor G C-terminus 400 481 2.0E-26 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Gene3D G3DSA:3.30.70.240 405 484 8.3E-22 T 28-03-2018 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Pfam PF00009 Elongation factor Tu GTP binding domain 7 199 9.1E-54 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 SUPERFAMILY SSF54980 402 517 2.52E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 PRINTS PR00315 GTP-binding elongation factor signature 125 134 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 PRINTS PR00315 GTP-binding elongation factor signature 73 83 1.1E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Gene3D G3DSA:3.40.50.300 70 190 5.0E-31 T 28-03-2018 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 603 1.7E-283 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 SMART SM00838 402 487 2.6E-7 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 148 2.6E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Gene3D G3DSA:2.40.30.10 191 304 5.6E-20 T 28-03-2018 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Gene3D G3DSA:2.40.50.250 487 577 7.2E-36 T 28-03-2018 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 Pfam PF03144 Elongation factor Tu domain 2 223 293 6.7E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CPF12_RS02135 03ce1422bb66cb712834735d2bae8a6f 609 SUPERFAMILY SSF54980 306 391 5.04E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 SUPERFAMILY SSF55874 175 341 1.57E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 Gene3D G3DSA:3.30.565.10 189 343 1.5E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 233 341 1.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 SUPERFAMILY SSF47384 102 183 6.08E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 SMART SM00387 231 343 1.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 Pfam PF00512 His Kinase A (phospho-acceptor) domain 120 182 5.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 SMART SM00388 119 185 6.2E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 Gene3D G3DSA:1.10.287.130 102 180 2.4E-10 T 28-03-2018 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 268 282 3.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 321 3.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 340 3.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS11745 b2484b5e97ac217d8034998877ed1cd8 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 296 3.6E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 Pfam PF01966 HD domain 336 428 1.2E-19 T 28-03-2018 IPR006674 HD domain CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 SMART SM00322 208 275 2.2E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 Gene3D G3DSA:1.10.3210.10 245 477 5.4E-36 T 28-03-2018 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 Pfam PF12072 Domain of unknown function (DUF3552) 6 204 4.6E-61 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 SUPERFAMILY SSF109604 325 470 3.59E-30 T 28-03-2018 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 TIGRFAM TIGR00277 HDIG: HDIG domain 332 409 1.1E-25 T 28-03-2018 IPR006675 HDIG domain CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 Gene3D G3DSA:3.30.300.20 107 244 1.6E-10 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 SUPERFAMILY SSF54791 208 304 2.64E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 Hamap MF_00335 Ribonuclease Y [rny]. 1 520 25.442 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 SMART SM00471 332 438 4.0E-13 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 520 3.4E-236 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CPF12_RS00005 0491c1312aa2be859f6284c2f10f7eec 520 Pfam PF00013 KH domain 213 270 1.2E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS00885 8a2af406a28737b1bbf15928afa6b71d 173 Gene3D G3DSA:3.40.50.880 2 173 9.0E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00885 8a2af406a28737b1bbf15928afa6b71d 173 Pfam PF01965 DJ-1/PfpI family 6 169 3.0E-43 T 28-03-2018 IPR002818 DJ-1/PfpI CPF12_RS00885 8a2af406a28737b1bbf15928afa6b71d 173 SUPERFAMILY SSF52317 5 171 2.38E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00885 8a2af406a28737b1bbf15928afa6b71d 173 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 7 171 8.3E-51 T 28-03-2018 IPR006286 Peptidase C56, PfpI CPF12_RS07905 3f34a583c3aac487c96e847293ef546d 190 Gene3D G3DSA:2.40.260.10 20 189 2.1E-36 T 28-03-2018 IPR023365 Sortase domain CPF12_RS07905 3f34a583c3aac487c96e847293ef546d 190 Pfam PF04203 Sortase family 66 185 2.7E-28 T 28-03-2018 IPR005754 Sortase family CPF12_RS07905 3f34a583c3aac487c96e847293ef546d 190 SUPERFAMILY SSF63817 37 187 1.27E-36 T 28-03-2018 IPR023365 Sortase domain CPF12_RS07905 3f34a583c3aac487c96e847293ef546d 190 TIGRFAM TIGR01076 sortase_fam: sortase 64 184 1.9E-30 T 28-03-2018 IPR005754 Sortase family CPF12_RS08470 f4b307dc2d53f569074fdfbbbc12ba37 422 Gene3D G3DSA:3.40.718.10 1 422 1.4E-130 T 28-03-2018 CPF12_RS08470 f4b307dc2d53f569074fdfbbbc12ba37 422 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 6 416 2.1E-176 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CPF12_RS08470 f4b307dc2d53f569074fdfbbbc12ba37 422 SUPERFAMILY SSF53659 6 419 5.18E-133 T 28-03-2018 CPF12_RS08470 f4b307dc2d53f569074fdfbbbc12ba37 422 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 21 415 9.2E-113 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CPF12_RS08470 f4b307dc2d53f569074fdfbbbc12ba37 422 SMART SM01329 20 416 1.8E-173 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CPF12_RS08470 f4b307dc2d53f569074fdfbbbc12ba37 422 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CPF12_RS02405 0c8d2f3bb7aef5ff0997b0e4136f6548 525 SUPERFAMILY SSF49401 178 299 4.22E-9 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS02405 0c8d2f3bb7aef5ff0997b0e4136f6548 525 Gene3D G3DSA:2.60.40.1280 21 170 6.5E-19 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CPF12_RS02405 0c8d2f3bb7aef5ff0997b0e4136f6548 525 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 488 513 0.0032 T 28-03-2018 CPF12_RS02405 0c8d2f3bb7aef5ff0997b0e4136f6548 525 SUPERFAMILY SSF49401 26 170 1.37E-12 T 28-03-2018 IPR008966 Adhesion domain CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 Pfam PF00266 Aminotransferase class-V 23 394 2.1E-156 T 28-03-2018 IPR000192 Aminotransferase class V domain CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 405 9.3E-187 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 Gene3D G3DSA:3.40.640.10 32 280 1.1E-60 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 SUPERFAMILY SSF53383 2 399 3.76E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 PIRSF PIRSF005572 20 405 1.6E-48 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CPF12_RS07830 d33441ec1f09f60d75b98e11f460380c 410 Gene3D G3DSA:3.90.1150.10 281 401 1.3E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 SUPERFAMILY SSF69864 171 396 3.14E-90 T 28-03-2018 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 Pfam PF00764 Arginosuccinate synthase 6 391 5.4E-171 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 53.165 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 Gene3D G3DSA:3.90.1260.10 157 352 7.5E-83 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 393 3.2E-166 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 Gene3D G3DSA:3.40.50.620 3 156 4.8E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 Gene3D G3DSA:1.20.5.470 362 395 1.1E-10 T 28-03-2018 CPF12_RS01640 4dc3e58f0515efde503e4fc7bc2e0326 404 SUPERFAMILY SSF52402 2 163 7.72E-46 T 28-03-2018 CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 Pfam PF00271 Helicase conserved C-terminal domain 231 336 1.9E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 Gene3D G3DSA:3.40.50.300 3 220 8.4E-56 T 28-03-2018 CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 SUPERFAMILY SSF52540 72 358 2.97E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 SMART SM00487 23 220 5.5E-57 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 Pfam PF03880 DbpA RNA binding domain 408 477 2.3E-19 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 Gene3D G3DSA:3.40.50.300 221 447 8.9E-45 T 28-03-2018 CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 Pfam PF00270 DEAD/DEAH box helicase 28 194 5.2E-47 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS09125 4ffd145b061acc4a8269c371165c9541 495 SMART SM00490 256 337 5.5E-30 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS07750 9ffc7cdbc979ec0ed35a6946b0f1e91b 543 Pfam PF00128 Alpha amylase, catalytic domain 22 369 3.8E-99 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS07750 9ffc7cdbc979ec0ed35a6946b0f1e91b 543 SMART SM00642 7 395 2.9E-116 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS07750 9ffc7cdbc979ec0ed35a6946b0f1e91b 543 Pfam PF11941 Domain of unknown function (DUF3459) 452 515 9.4E-6 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CPF12_RS07750 9ffc7cdbc979ec0ed35a6946b0f1e91b 543 Gene3D G3DSA:3.20.20.80 2 466 4.2E-98 T 28-03-2018 CPF12_RS07750 9ffc7cdbc979ec0ed35a6946b0f1e91b 543 SUPERFAMILY SSF51445 4 466 2.52E-118 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07750 9ffc7cdbc979ec0ed35a6946b0f1e91b 543 Gene3D G3DSA:2.60.40.1180 473 541 0.0045 T 28-03-2018 CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Gene3D G3DSA:2.160.10.10 129 233 2.8E-31 T 28-03-2018 CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 44.017 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Gene3D G3DSA:3.30.70.250 3 73 3.5E-35 T 28-03-2018 CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 SUPERFAMILY SSF51161 44 225 2.09E-52 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 4.1E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 1.8E-32 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 1.6E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 118 2.2E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 Gene3D G3DSA:2.160.10.10 74 128 4.9E-11 T 28-03-2018 CPF12_RS08620 2944aefc9e6222f9feb1b34d0aa6f616 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 2.0E-112 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 Gene3D G3DSA:3.10.25.10 208 313 1.4E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 SUPERFAMILY SSF53328 3 204 5.1E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 Pfam PF02911 Formyl transferase, C-terminal domain 205 302 7.5E-23 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 Gene3D G3DSA:3.40.50.170 1 207 3.8E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 305 2.3E-94 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 Pfam PF00551 Formyl transferase 3 181 8.0E-37 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 34.152 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS11455 24d1f16f5a13df014d641d0e9bc92688 314 SUPERFAMILY SSF50486 206 305 1.07E-24 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 SUPERFAMILY SSF49899 341 474 1.82E-24 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 Gene3D G3DSA:2.60.120.560 352 482 6.4E-23 T 28-03-2018 CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 Gene3D G3DSA:2.115.10.20 3 351 5.7E-78 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 38 51 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 SMART SM00640 38 451 9.6E-123 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 350 473 4.5E-18 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 462 3.4E-160 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 38 341 6.4E-90 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CPF12_RS07870 88a10e85249be151bd78ea84ed0a53d6 486 SUPERFAMILY SSF75005 29 342 6.44E-94 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 Gene3D G3DSA:2.40.40.10 87 278 7.3E-32 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 Gene3D G3DSA:3.10.350.10 25 78 1.3E-14 T 28-03-2018 CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 SUPERFAMILY SSF50685 219 259 1.95E-5 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 SUPERFAMILY SSF54106 78 120 2.35E-11 T 28-03-2018 IPR018392 LysM domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 Pfam PF06725 3D domain 220 278 5.1E-16 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 SUPERFAMILY SSF54106 30 72 2.88E-10 T 28-03-2018 IPR018392 LysM domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 SMART SM00257 78 121 1.2E-15 T 28-03-2018 IPR018392 LysM domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 SMART SM00257 30 73 8.0E-15 T 28-03-2018 IPR018392 LysM domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 Pfam PF01476 LysM domain 31 72 7.0E-13 T 28-03-2018 IPR018392 LysM domain CPF12_RS03830 bbad1b31fdb3a6cc3456a684b5fa9ff4 279 Pfam PF01476 LysM domain 79 120 2.1E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS02330 b2e7637f3304e9a1fa9826fe0f0053cf 328 SUPERFAMILY SSF47954 256 324 2.38E-5 T 28-03-2018 IPR013763 Cyclin-like CPF12_RS02330 b2e7637f3304e9a1fa9826fe0f0053cf 328 Gene3D G3DSA:1.10.10.60 263 322 0.0011 T 28-03-2018 CPF12_RS10215 0f8bb66b840a4ea7e671c63439163400 306 Pfam PF01040 UbiA prenyltransferase family 31 274 2.4E-33 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CPF12_RS10215 0f8bb66b840a4ea7e671c63439163400 306 PIRSF PIRSF005355 5 305 3.5E-69 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CPF12_RS10215 0f8bb66b840a4ea7e671c63439163400 306 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 22 298 4.6E-33 T 28-03-2018 CPF12_RS10215 0f8bb66b840a4ea7e671c63439163400 306 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 13 300 17.584 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 SUPERFAMILY SSF50447 3 91 6.89E-19 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 169 5.3E-49 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 Pfam PF01782 RimM N-terminal domain 7 90 1.5E-19 T 28-03-2018 IPR002676 RimM protein GO:0006364 CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 SUPERFAMILY SSF50346 100 170 4.71E-20 T 28-03-2018 IPR011033 PRC-barrel-like CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 Pfam PF05239 PRC-barrel domain 97 170 3.6E-13 T 28-03-2018 IPR027275 PRC-barrel domain CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 Gene3D G3DSA:2.40.30.60 2 95 9.8E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 24.378 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CPF12_RS11635 151ed29951f615851e87a3e00dd380f4 172 Gene3D G3DSA:2.30.30.240 96 165 2.7E-23 T 28-03-2018 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 Gene3D G3DSA:3.40.710.10 280 604 1.2E-63 T 28-03-2018 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 SUPERFAMILY SSF54427 43 157 5.92E-20 T 28-03-2018 IPR032710 NTF2-like domain CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 Gene3D G3DSA:3.90.1310.10 165 279 1.3E-19 T 28-03-2018 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 SUPERFAMILY SSF56601 274 603 4.78E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 Gene3D G3DSA:3.10.450.100 38 154 1.5E-23 T 28-03-2018 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 44 159 1.8E-23 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 Pfam PF03717 Penicillin-binding Protein dimerisation domain 187 259 9.0E-12 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 SUPERFAMILY SSF56519 162 273 1.77E-14 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS06290 5a71d2054c5c5ca92f7caf999858b626 604 Pfam PF00905 Penicillin binding protein transpeptidase domain 292 585 1.3E-61 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 24 194 29.478 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 Gene3D G3DSA:3.10.20.80 26 102 7.6E-30 T 28-03-2018 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 31 100 3.8E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 31 193 9.0E-71 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 108 192 1.2E-37 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 SUPERFAMILY SSF55200 107 193 1.57E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 SUPERFAMILY SSF54364 29 102 1.83E-27 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 ProSitePatterns PS00938 Initiation factor 3 signature. 82 95 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CPF12_RS02515 3516288799f1046dea63bc2bc82c8d2a 194 Gene3D G3DSA:3.30.110.10 103 194 2.0E-35 T 28-03-2018 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 2.4E-32 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Gene3D G3DSA:3.40.50.300 75 192 4.8E-32 T 28-03-2018 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Gene3D G3DSA:2.40.30.10 300 392 1.4E-31 T 28-03-2018 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 392 3.6E-233 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 5.6E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Gene3D G3DSA:3.40.50.300 1 74 1.2E-10 T 28-03-2018 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 SUPERFAMILY SSF52540 10 226 3.42E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.02 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 146 4.4E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 SUPERFAMILY SSF50447 203 301 1.51E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.1E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.1E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.1E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 SUPERFAMILY SSF50465 302 394 4.52E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Gene3D G3DSA:2.40.30.10 193 298 3.0E-32 T 28-03-2018 CPF12_RS06045 8e7db68a12eecc9a5cd6ac3f063931b3 394 Pfam PF00009 Elongation factor Tu GTP binding domain 11 201 8.9E-60 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 Gene3D G3DSA:1.20.59.10 4 90 1.2E-20 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 SUPERFAMILY SSF51569 25 354 2.84E-103 T 28-03-2018 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 Gene3D G3DSA:3.20.20.70 95 356 9.9E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 Pfam PF00793 DAHP synthetase I family 109 349 3.2E-81 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 1.5E-32 T 28-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 SMART SM00830 10 89 4.9E-17 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 2.0E-119 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CPF12_RS09915 a8ecfb47eece2dbf061d7b343e15eb90 356 Pfam PF01817 Chorismate mutase type II 10 86 3.9E-14 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CPF12_RS04590 d1d0d1794cfa191aa2a50f7053a1a9a0 515 Pfam PF03793 PASTA domain 273 334 1.2E-7 T 28-03-2018 IPR005543 PASTA domain CPF12_RS04590 d1d0d1794cfa191aa2a50f7053a1a9a0 515 Pfam PF03793 PASTA domain 127 188 4.6E-5 T 28-03-2018 IPR005543 PASTA domain CPF12_RS04590 d1d0d1794cfa191aa2a50f7053a1a9a0 515 SMART SM00740 269 335 1.3E-7 T 28-03-2018 IPR005543 PASTA domain CPF12_RS04590 d1d0d1794cfa191aa2a50f7053a1a9a0 515 SMART SM00740 123 189 1.4E-6 T 28-03-2018 IPR005543 PASTA domain CPF12_RS04590 d1d0d1794cfa191aa2a50f7053a1a9a0 515 SMART SM00740 337 398 9.0 T 28-03-2018 IPR005543 PASTA domain CPF12_RS04590 d1d0d1794cfa191aa2a50f7053a1a9a0 515 SMART SM00740 193 264 3.6 T 28-03-2018 IPR005543 PASTA domain CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SUPERFAMILY SSF48452 176 410 1.05E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 2 49 0.031 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Pfam PF13176 Tetratricopeptide repeat 176 199 0.0031 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 104 184 1.1E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SUPERFAMILY SSF48452 32 201 4.55E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Pfam PF13181 Tetratricopeptide repeat 347 373 0.017 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 134 167 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 341 374 39.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 100 133 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 272 305 73.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 66 99 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 205 237 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 SMART SM00028 171 204 0.0052 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 50 103 5.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 286 317 6.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 185 214 3.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 215 285 2.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09565 213c3f4211c492501bcc39e3b634d9ee 422 Gene3D G3DSA:1.25.40.10 318 422 3.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS05115 d7a295c1ad14bb52c892672f27b791bb 62 Gene3D G3DSA:1.10.3100.10 1 62 7.3E-21 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS05115 d7a295c1ad14bb52c892672f27b791bb 62 Pfam PF12844 Helix-turn-helix domain 4 56 3.9E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05115 d7a295c1ad14bb52c892672f27b791bb 62 SMART SM00530 5 60 2.3E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05115 d7a295c1ad14bb52c892672f27b791bb 62 SUPERFAMILY SSF47413 2 60 2.2E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS02475 35207a0fed1927a5a2706577f3b95777 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 283 7.1E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02475 35207a0fed1927a5a2706577f3b95777 294 Gene3D G3DSA:1.20.58.370 2 41 7.8E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CPF12_RS02475 35207a0fed1927a5a2706577f3b95777 294 SUPERFAMILY SSF161098 56 284 2.35E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02475 35207a0fed1927a5a2706577f3b95777 294 Gene3D G3DSA:1.10.3720.10 62 292 5.8E-43 T 28-03-2018 CPF12_RS02475 35207a0fed1927a5a2706577f3b95777 294 SUPERFAMILY SSF160964 10 47 3.66E-5 T 28-03-2018 CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 Gene3D G3DSA:3.30.230.40 90 195 3.0E-30 T 28-03-2018 CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 SUPERFAMILY SSF54211 1 85 1.16E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 SUPERFAMILY SSF54211 88 178 3.29E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 3.2E-63 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 Gene3D G3DSA:3.30.230.40 2 88 1.6E-31 T 28-03-2018 CPF12_RS00100 c39d6e616b947b2a83e90e4329546faa 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 40.583 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 Pfam PF00005 ABC transporter 336 468 1.1E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 Pfam PF00005 ABC transporter 19 185 7.2E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 SUPERFAMILY SSF52540 3 93 5.96E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 SUPERFAMILY SSF52540 126 256 5.96E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 SMART SM00382 345 513 12.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 SMART SM00382 27 229 4.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 Pfam PF12848 ABC transporter 225 309 2.6E-18 T 28-03-2018 IPR032781 ABC-transporter extension domain CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 Gene3D G3DSA:3.40.50.300 286 529 3.2E-33 T 28-03-2018 CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 SUPERFAMILY SSF52540 297 514 2.13E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12105 7dca7f4c9a0218607bdd2aa60c146049 529 Gene3D G3DSA:3.40.50.300 1 285 1.2E-51 T 28-03-2018 CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 Gene3D G3DSA:1.10.10.10 6 74 7.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 SUPERFAMILY SSF46785 9 79 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 211 28.477 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 Pfam PF06971 Putative DNA-binding protein N-terminus 8 55 7.1E-16 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 Gene3D G3DSA:3.40.50.720 75 190 3.7E-7 T 28-03-2018 CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 SUPERFAMILY SSF51735 89 204 1.28E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS02230 afd478e2254ef8f1a54fee55ddfe31ed 221 Pfam PF02629 CoA binding domain 88 180 4.6E-9 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CPF12_RS09760 d1cab5f4c4ff65fdbc7c73dfa6c29830 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 25.159 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CPF12_RS09760 d1cab5f4c4ff65fdbc7c73dfa6c29830 117 Gene3D G3DSA:3.30.460.10 1 115 8.3E-34 T 28-03-2018 CPF12_RS09760 d1cab5f4c4ff65fdbc7c73dfa6c29830 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 104 3.4E-36 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CPF12_RS09760 d1cab5f4c4ff65fdbc7c73dfa6c29830 117 SUPERFAMILY SSF81301 2 113 1.37E-39 T 28-03-2018 CPF12_RS09760 d1cab5f4c4ff65fdbc7c73dfa6c29830 117 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 3.8E-27 T 28-03-2018 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 SUPERFAMILY SSF52518 5 324 3.54E-115 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 662 3.0E-286 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 Pfam PF02780 Transketolase, C-terminal domain 551 656 3.7E-13 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 Gene3D G3DSA:3.40.50.920 538 663 2.6E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 SUPERFAMILY SSF52518 340 525 1.28E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 337 1.6E-147 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 SMART SM00861 353 524 3.5E-65 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 Pfam PF02779 Transketolase, pyrimidine binding domain 354 523 1.5E-43 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 Gene3D G3DSA:3.40.50.970 353 533 2.5E-43 T 28-03-2018 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 Gene3D G3DSA:3.40.50.970 3 352 2.8E-106 T 28-03-2018 CPF12_RS12430 46ee80a0fac02c3de05c1d4f4b67a86e 663 SUPERFAMILY SSF52922 534 663 1.09E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS03445 fe60609a5888c766ca42d651ea371d59 178 Gene3D G3DSA:3.40.630.30 5 177 2.1E-19 T 28-03-2018 CPF12_RS03445 fe60609a5888c766ca42d651ea371d59 178 SUPERFAMILY SSF55729 18 168 1.01E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS03445 fe60609a5888c766ca42d651ea371d59 178 Pfam PF00583 Acetyltransferase (GNAT) family 60 159 1.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS01070 2666a581473481f1df31771f2516342a 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.066 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01070 2666a581473481f1df31771f2516342a 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.7E-40 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01070 2666a581473481f1df31771f2516342a 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS01070 2666a581473481f1df31771f2516342a 102 SUPERFAMILY SSF141091 1 101 6.67E-40 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01070 2666a581473481f1df31771f2516342a 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.6E-42 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Pfam PF03129 Anticodon binding domain 544 632 6.8E-24 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Gene3D G3DSA:3.40.50.800 535 640 4.4E-30 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 65 638 34.423 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 SUPERFAMILY SSF52954 532 637 2.42E-32 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Gene3D G3DSA:3.30.980.10 64 143 3.1E-26 T 28-03-2018 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 SMART SM00863 166 215 6.2E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 SUPERFAMILY SSF55186 63 237 6.67E-62 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Gene3D G3DSA:3.10.20.30 1 61 8.2E-16 T 28-03-2018 IPR012675 Beta-grasp domain CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 SUPERFAMILY SSF81271 2 60 8.72E-15 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 532 8.3E-33 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Gene3D G3DSA:3.30.930.10 217 534 9.3E-105 T 28-03-2018 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 633 8.2E-233 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Gene3D G3DSA:3.30.54.20 144 183 1.5E-18 T 28-03-2018 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 SUPERFAMILY SSF55681 239 529 1.31E-96 T 28-03-2018 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 166 215 6.6E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 537 549 1.2E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 1.2E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 1.2E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 467 495 1.2E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 510 523 1.2E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CPF12_RS08505 1412e66081645068a8cc1d2066f15f50 640 Pfam PF02824 TGS domain 1 60 6.9E-9 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CPF12_RS08510 22506259a53b327134b95fff0c9a2d16 474 Pfam PF13347 MFS/sugar transport protein 17 446 2.0E-78 T 28-03-2018 CPF12_RS08510 22506259a53b327134b95fff0c9a2d16 474 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 15 459 1.3E-76 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CPF12_RS08510 22506259a53b327134b95fff0c9a2d16 474 Gene3D G3DSA:1.20.1250.20 222 470 5.4E-21 T 28-03-2018 CPF12_RS08510 22506259a53b327134b95fff0c9a2d16 474 SUPERFAMILY SSF103473 13 448 3.53E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS08510 22506259a53b327134b95fff0c9a2d16 474 Gene3D G3DSA:1.20.1250.20 13 221 1.2E-19 T 28-03-2018 CPF12_RS03970 552427844388649f0b7466ea76068de6 340 SUPERFAMILY SSF55021 252 333 8.58E-17 T 28-03-2018 CPF12_RS03970 552427844388649f0b7466ea76068de6 340 Pfam PF00005 ABC transporter 21 169 5.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03970 552427844388649f0b7466ea76068de6 340 Gene3D G3DSA:3.40.50.300 1 252 5.9E-76 T 28-03-2018 CPF12_RS03970 552427844388649f0b7466ea76068de6 340 SMART SM00930 260 335 1.5E-21 T 28-03-2018 IPR018449 NIL domain CPF12_RS03970 552427844388649f0b7466ea76068de6 340 SUPERFAMILY SSF52540 1 240 2.24E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03970 552427844388649f0b7466ea76068de6 340 Pfam PF09383 NIL domain 263 333 2.0E-15 T 28-03-2018 IPR018449 NIL domain CPF12_RS03970 552427844388649f0b7466ea76068de6 340 SMART SM00382 30 221 1.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03970 552427844388649f0b7466ea76068de6 340 Gene3D G3DSA:3.30.70.260 253 334 2.9E-17 T 28-03-2018 CPF12_RS03970 552427844388649f0b7466ea76068de6 340 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 Pfam PF00800 Prephenate dehydratase 3 184 1.8E-51 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 SUPERFAMILY SSF53850 2 189 6.52E-49 T 28-03-2018 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 Gene3D G3DSA:3.40.190.10 1 92 1.8E-24 T 28-03-2018 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 PIRSF PIRSF001500 1 279 2.4E-63 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 224 231 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 SUPERFAMILY SSF55021 177 275 6.87E-22 T 28-03-2018 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 Gene3D G3DSA:3.40.190.10 93 165 3.7E-24 T 28-03-2018 CPF12_RS00990 9ba08a4a2e15318049809431e9e3be6e 280 Gene3D G3DSA:3.30.70.260 186 279 1.9E-22 T 28-03-2018 CPF12_RS04090 04c58840628bb96a10f9d1ea3f8d8b3e 212 SUPERFAMILY SSF141571 49 209 1.44E-36 T 28-03-2018 CPF12_RS04090 04c58840628bb96a10f9d1ea3f8d8b3e 212 Gene3D G3DSA:2.160.10.20 43 118 1.5E-14 T 28-03-2018 CPF12_RS04090 04c58840628bb96a10f9d1ea3f8d8b3e 212 Gene3D G3DSA:2.160.10.20 119 206 5.3E-12 T 28-03-2018 CPF12_RS04090 04c58840628bb96a10f9d1ea3f8d8b3e 212 Pfam PF00805 Pentapeptide repeats (8 copies) 159 180 0.001 T 28-03-2018 IPR001646 Pentapeptide repeat CPF12_RS04090 04c58840628bb96a10f9d1ea3f8d8b3e 212 Pfam PF13599 Pentapeptide repeats (9 copies) 67 141 1.2E-10 T 28-03-2018 IPR001646 Pentapeptide repeat CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 SUPERFAMILY SSF46785 7 138 5.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 Pfam PF12802 MarR family 33 86 1.9E-13 T 28-03-2018 CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 SMART SM00347 22 122 6.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 4.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 4.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 4.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00470 2b5fa3818480e4632e356ef3c0e5b87d 147 Gene3D G3DSA:1.10.10.10 3 133 6.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 TIGRFAM TIGR01393 lepA: elongation factor 4 11 605 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 SMART SM00838 410 495 5.2E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Pfam PF00009 Elongation factor Tu GTP binding domain 11 190 1.3E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Pfam PF00679 Elongation factor G C-terminus 409 495 1.2E-23 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 SUPERFAMILY SSF52540 9 214 1.6E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Gene3D G3DSA:3.30.70.240 405 559 6.0E-30 T 28-03-2018 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 1.0E-50 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 184 2.0E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 SUPERFAMILY SSF50447 175 297 1.87E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Pfam PF03144 Elongation factor Tu domain 2 214 284 5.2E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 SUPERFAMILY SSF54980 301 379 1.26E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 SUPERFAMILY SSF54980 408 503 3.69E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Gene3D G3DSA:3.30.70.870 297 376 3.4E-27 T 28-03-2018 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 303.547 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Gene3D G3DSA:3.40.50.300 8 194 6.9E-36 T 28-03-2018 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 PRINTS PR00315 GTP-binding elongation factor signature 15 28 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.6E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS09810 1c43f2d72abeb6d3583b1161e31fa9e0 610 Gene3D G3DSA:2.40.30.10 197 296 2.8E-27 T 28-03-2018 CPF12_RS06200 7cd5b04506beba3cf60104273aa70d91 281 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 275 5.4E-118 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CPF12_RS06200 7cd5b04506beba3cf60104273aa70d91 281 SUPERFAMILY SSF52540 6 233 1.86E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06200 7cd5b04506beba3cf60104273aa70d91 281 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06200 7cd5b04506beba3cf60104273aa70d91 281 SMART SM00382 34 219 4.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06200 7cd5b04506beba3cf60104273aa70d91 281 Gene3D G3DSA:3.40.50.300 2 245 5.6E-68 T 28-03-2018 CPF12_RS06200 7cd5b04506beba3cf60104273aa70d91 281 Pfam PF00005 ABC transporter 25 171 1.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 187 2.6E-5 T 28-03-2018 CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 Gene3D G3DSA:3.40.50.720 48 247 2.0E-58 T 28-03-2018 CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 1.5E-52 T 28-03-2018 CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 Gene3D G3DSA:3.40.50.10090 2 47 1.7E-6 T 28-03-2018 CPF12_RS00505 1b07e9c4e75f8d02083550d9f016a6fd 247 SUPERFAMILY SSF51735 9 246 6.75E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11615 7111ff0fb3af4f91c940b76a4b848247 112 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 93 7.0E-37 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CPF12_RS11615 7111ff0fb3af4f91c940b76a4b848247 112 Hamap MF_00245 UPF0122 protein . 2 103 20.042 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CPF12_RS11615 7111ff0fb3af4f91c940b76a4b848247 112 Gene3D G3DSA:1.10.10.10 1 110 9.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11615 7111ff0fb3af4f91c940b76a4b848247 112 SUPERFAMILY SSF88659 1 97 1.1E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 Gene3D G3DSA:3.40.50.300 467 689 7.7E-52 T 28-03-2018 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 Pfam PF13361 UvrD-like helicase C-terminal domain 280 618 4.5E-72 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 3.1E-86 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 Gene3D G3DSA:3.40.50.300 148 284 1.5E-34 T 28-03-2018 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 Gene3D G3DSA:3.40.50.300 3 147 6.1E-31 T 28-03-2018 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 Gene3D G3DSA:3.40.50.300 285 386 1.5E-28 T 28-03-2018 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 734 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CPF12_RS08735 57ee8fa75615dd64f826589a6bccca3c 736 SUPERFAMILY SSF52540 4 645 2.32E-186 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 Gene3D G3DSA:3.40.50.300 1 282 2.7E-70 T 28-03-2018 CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 Pfam PF00005 ABC transporter 23 164 1.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 Pfam PF08402 TOBE domain 281 353 3.3E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 SUPERFAMILY SSF52540 5 245 3.9E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 SMART SM00382 29 214 4.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04420 372024826bbbbd8efcae6bdc064637a0 370 SUPERFAMILY SSF50331 241 361 4.76E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CPF12_RS09050 2328e3a51be7783c5a72a1f4b994b749 114 Pfam PF01740 STAS domain 9 101 9.6E-14 T 28-03-2018 IPR002645 STAS domain CPF12_RS09050 2328e3a51be7783c5a72a1f4b994b749 114 Gene3D G3DSA:3.30.750.24 3 110 7.5E-16 T 28-03-2018 IPR002645 STAS domain CPF12_RS09050 2328e3a51be7783c5a72a1f4b994b749 114 SUPERFAMILY SSF52091 9 103 1.02E-20 T 28-03-2018 IPR002645 STAS domain CPF12_RS09050 2328e3a51be7783c5a72a1f4b994b749 114 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 105 8.9E-25 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 SUPERFAMILY SSF48557 9 458 4.4E-148 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 Pfam PF00206 Lyase 9 303 6.2E-74 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 458 7.5E-193 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00145 Argininosuccinate lyase family signature 313 332 6.7E-69 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 6.7E-69 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00145 Argininosuccinate lyase family signature 278 294 6.7E-69 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 6.7E-69 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00145 Argininosuccinate lyase family signature 196 212 6.7E-69 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00145 Argininosuccinate lyase family signature 234 258 6.7E-69 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 Pfam PF14698 Argininosuccinate lyase C-terminal 366 434 1.7E-24 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 Hamap MF_00006 Argininosuccinate lyase [argH]. 5 456 42.794 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 Gene3D G3DSA:1.10.40.30 378 435 8.9E-25 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 Gene3D G3DSA:1.20.200.10 110 377 1.0E-90 T 28-03-2018 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 Gene3D G3DSA:1.10.275.10 5 109 1.0E-33 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 ProSitePatterns PS00163 Fumarate lyases signature. 278 287 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 3.5E-29 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00149 Fumarate lyase superfamily signature 234 261 3.5E-29 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 3.5E-29 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS01645 74c8330036fbbfbe212c738ac8dd701a 459 PRINTS PR00149 Fumarate lyase superfamily signature 278 294 3.5E-29 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS11950 05765726b1f09c1b2017f5aa38458910 313 SUPERFAMILY SSF52540 5 223 1.88E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11950 05765726b1f09c1b2017f5aa38458910 313 Pfam PF00005 ABC transporter 23 166 7.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11950 05765726b1f09c1b2017f5aa38458910 313 SMART SM00382 31 214 7.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11950 05765726b1f09c1b2017f5aa38458910 313 Gene3D G3DSA:3.40.50.300 2 273 3.1E-54 T 28-03-2018 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 Gene3D G3DSA:2.30.22.10 133 189 6.0E-21 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 Gene3D G3DSA:3.90.20.20 5 131 7.8E-24 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 Hamap MF_01151 Protein GrpE [grpE]. 2 189 19.847 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 SUPERFAMILY SSF58014 42 133 1.57E-22 T 28-03-2018 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 SUPERFAMILY SSF51064 134 189 7.19E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 ProSitePatterns PS01071 grpE protein signature. 144 187 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 PRINTS PR00773 GrpE protein signature 168 187 2.3E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 PRINTS PR00773 GrpE protein signature 87 102 2.3E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 PRINTS PR00773 GrpE protein signature 141 156 2.3E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 PRINTS PR00773 GrpE protein signature 59 75 2.3E-29 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS09285 4aa79dc6c49010b7fed111bd31d0a3c8 189 Pfam PF01025 GrpE 27 189 1.1E-50 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CPF12_RS04905 513ba18f9d077b058e1060defe4a987d 360 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 5 335 2.3E-83 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CPF12_RS04905 513ba18f9d077b058e1060defe4a987d 360 Pfam PF02378 Phosphotransferase system, EIIC 14 206 9.2E-9 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 136 2.1E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 344 1.1E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.211 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Gene3D G3DSA:1.20.120.430 71 241 5.4E-44 T 28-03-2018 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Gene3D G3DSA:1.20.120.430 242 360 9.0E-14 T 28-03-2018 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Gene3D G3DSA:3.30.300.20 361 434 1.3E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 3.4E-33 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 8.6E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 8.6E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 PIRSF PIRSF006485 2 436 2.2E-176 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 SUPERFAMILY SSF52540 5 169 1.53E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 SUPERFAMILY SSF52540 138 435 5.35E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 2.8E-179 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Gene3D G3DSA:1.20.120.430 1 70 8.5E-18 T 28-03-2018 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Pfam PF01926 50S ribosome-binding GTPase 179 295 7.2E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09475 b90473c399a2e2d7843f5f2e565f578d 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.6E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 SUPERFAMILY SSF46934 4 55 5.11E-20 T 28-03-2018 IPR009060 UBA-like GO:0005515 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 SUPERFAMILY SSF54713 56 146 3.14E-21 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 Pfam PF00889 Elongation factor TS 71 275 1.5E-71 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 Gene3D G3DSA:3.30.479.20 158 291 1.1E-49 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 Gene3D G3DSA:3.30.479.20 58 157 1.6E-22 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 Gene3D G3DSA:1.10.8.10 1 56 4.2E-26 T 28-03-2018 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 SUPERFAMILY SSF54713 153 293 1.7E-51 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 292 79.752 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 4.2E-115 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS12340 5d6069714778abdd8dc868445434203d 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.0E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.0E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.0E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.0E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 39.07 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 Gene3D G3DSA:3.90.230.10 1 249 7.2E-80 T 28-03-2018 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 2.9E-88 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 SUPERFAMILY SSF55920 1 247 6.28E-85 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS08375 ebe4f68c222d8929927d03529efa7b1f 252 Pfam PF00557 Metallopeptidase family M24 11 239 3.7E-50 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS01800 681551e9e9cbedb5af548456beb84c7a 342 Gene3D G3DSA:3.40.50.970 3 322 4.1E-83 T 28-03-2018 CPF12_RS01800 681551e9e9cbedb5af548456beb84c7a 342 Pfam PF00676 Dehydrogenase E1 component 27 326 1.9E-97 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CPF12_RS01800 681551e9e9cbedb5af548456beb84c7a 342 SUPERFAMILY SSF52518 9 336 3.57E-103 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 SUPERFAMILY SSF55347 150 309 3.44E-44 T 28-03-2018 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 141 1.6E-27 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 340 8.0E-122 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 335 39.138 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 312 4.0E-25 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 Gene3D G3DSA:3.30.360.10 161 309 6.0E-50 T 28-03-2018 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 Gene3D G3DSA:3.40.50.720 1 160 1.7E-33 T 28-03-2018 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 SMART SM00859 2 142 1.3E-45 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CPF12_RS02320 5db9faf1e3f7e2e6233b31c07e6d7d50 341 SUPERFAMILY SSF51735 2 173 7.22E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 SUPERFAMILY SSF52777 201 421 5.34E-80 T 28-03-2018 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Gene3D G3DSA:3.90.1170.30 2 48 2.8E-16 T 28-03-2018 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Pfam PF00364 Biotin-requiring enzyme 5 77 9.5E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Pfam PF02817 e3 binding domain 125 159 2.1E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 SUPERFAMILY SSF47005 118 162 1.19E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Gene3D G3DSA:2.40.50.100 49 121 1.6E-4 T 28-03-2018 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Gene3D G3DSA:4.10.320.10 122 178 4.0E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 200 423 1.5E-79 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 SUPERFAMILY SSF51230 2 97 3.5E-27 T 28-03-2018 IPR011053 Single hybrid motif CPF12_RS01790 14ee3464e9a7e0417186f6ccfb250d87 430 Gene3D G3DSA:3.30.559.10 183 428 6.0E-87 T 28-03-2018 CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 Gene3D G3DSA:1.10.10.10 1 83 3.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 Pfam PF03466 LysR substrate binding domain 88 295 8.9E-24 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 Gene3D G3DSA:3.40.190.10 183 263 9.2E-4 T 28-03-2018 CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.8E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 SUPERFAMILY SSF46785 1 104 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 SUPERFAMILY SSF53850 89 295 3.14E-24 T 28-03-2018 CPF12_RS07470 403eed380ada8846b09f6133b38f5f71 303 Gene3D G3DSA:3.40.190.10 88 182 3.7E-14 T 28-03-2018 CPF12_RS06575 3e5c8d60e77bf686409ed3a3f57f2993 309 Pfam PF00535 Glycosyl transferase family 2 11 175 2.6E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CPF12_RS06575 3e5c8d60e77bf686409ed3a3f57f2993 309 Gene3D G3DSA:3.90.550.10 3 272 1.6E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS06575 3e5c8d60e77bf686409ed3a3f57f2993 309 SUPERFAMILY SSF53448 6 256 6.19E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 Pfam PF02934 GatB/GatE catalytic domain 6 286 9.3E-113 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 38.782 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 Gene3D G3DSA:1.10.10.410 413 474 3.1E-21 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 SUPERFAMILY SSF89095 295 401 2.88E-35 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 SMART SM00845 326 473 9.0E-78 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 Pfam PF02637 GatB domain 326 473 5.4E-55 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 SUPERFAMILY SSF55931 4 294 3.86E-120 T 28-03-2018 CPF12_RS08760 3af545484e9f13b7d822d099cb8f94e5 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 473 7.0E-175 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CPF12_RS11125 69715bd50eae173b78696336a09a5072 205 Pfam PF00005 ABC transporter 17 161 1.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11125 69715bd50eae173b78696336a09a5072 205 Gene3D G3DSA:3.40.50.300 1 205 7.5E-53 T 28-03-2018 CPF12_RS11125 69715bd50eae173b78696336a09a5072 205 SUPERFAMILY SSF52540 2 205 1.36E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11125 69715bd50eae173b78696336a09a5072 205 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11125 69715bd50eae173b78696336a09a5072 205 SMART SM00382 26 204 1.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PIRSF PIRSF036361 7 450 1.8E-150 T 28-03-2018 IPR011240 Phosphoesterase-related protein YunD CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 SUPERFAMILY SSF56300 7 253 6.39E-57 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PRINTS PR01607 Apyrase family signature 323 346 1.3E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PRINTS PR01607 Apyrase family signature 184 207 1.3E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PRINTS PR01607 Apyrase family signature 212 232 1.3E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PRINTS PR01607 Apyrase family signature 400 419 1.3E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PRINTS PR01607 Apyrase family signature 165 182 1.3E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 PRINTS PR01607 Apyrase family signature 8 26 1.3E-16 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 Gene3D G3DSA:3.60.21.10 10 277 1.0E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 Pfam PF00149 Calcineurin-like phosphoesterase 10 201 1.9E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 Gene3D G3DSA:3.90.780.10 278 450 2.4E-19 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 SUPERFAMILY SSF55816 274 445 1.24E-18 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS07940 909acb9189d474c0e07e9dd8fd60a9af 450 Pfam PF02872 5'-nucleotidase, C-terminal domain 284 413 7.1E-7 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CPF12_RS05305 f905d2b057ea8764baad3e175cb98d53 159 Pfam PF08670 MEKHLA domain 13 150 4.7E-34 T 28-03-2018 IPR013978 MEKHLA CPF12_RS05305 f905d2b057ea8764baad3e175cb98d53 159 SUPERFAMILY SSF55785 34 148 2.09E-10 T 28-03-2018 IPR000014 PAS domain CPF12_RS05305 f905d2b057ea8764baad3e175cb98d53 159 Gene3D G3DSA:3.30.450.20 22 150 7.9E-11 T 28-03-2018 CPF12_RS05305 f905d2b057ea8764baad3e175cb98d53 159 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 56 149 6.0E-6 T 28-03-2018 IPR000014 PAS domain CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 99 113 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 318 340 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 355 372 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 392 405 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 61 85 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 115 125 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 PRINTS PR00906 SecA protein signature 168 188 5.7E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Pfam PF02810 SEC-C motif 816 834 3.0E-9 T 28-03-2018 IPR004027 SEC-C motif CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Gene3D G3DSA:1.10.3060.10 583 676 6.3E-26 T 28-03-2018 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SUPERFAMILY SSF81767 225 347 1.7E-41 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 779 19.11 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SMART SM00957 5 381 8.1E-260 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SUPERFAMILY SSF81886 569 824 1.57E-76 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 ProSitePatterns PS01312 SecA family signature. 479 494 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Pfam PF07516 SecA Wing and Scaffold domain 566 776 2.8E-59 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SMART SM00958 226 337 2.9E-56 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Pfam PF07517 SecA DEAD-like domain 6 380 1.6E-121 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SUPERFAMILY SSF52540 6 226 2.48E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SUPERFAMILY SSF52540 347 394 2.48E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Pfam PF01043 SecA preprotein cross-linking domain 233 337 1.9E-35 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Gene3D G3DSA:3.10.450.50 677 835 1.2E-42 T 28-03-2018 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Gene3D G3DSA:3.40.50.300 8 267 8.2E-51 T 28-03-2018 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Gene3D G3DSA:3.40.50.300 298 395 6.0E-8 T 28-03-2018 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 495 1.3E-236 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 SUPERFAMILY SSF52540 396 563 7.72E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06645 e7704d6c5e6ad2381fe40704b1fcaf6b 836 Gene3D G3DSA:3.40.50.300 396 582 1.6E-51 T 28-03-2018 CPF12_RS08260 9df6fa3732ccb72323db81430f7c66ef 466 SUPERFAMILY SSF52540 187 330 6.97E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08260 9df6fa3732ccb72323db81430f7c66ef 466 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 132 430 3.0E-58 T 28-03-2018 IPR006500 DNA primase, phage/plasmid CPF12_RS08260 9df6fa3732ccb72323db81430f7c66ef 466 Gene3D G3DSA:1.10.10.10 389 459 0.0034 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08260 9df6fa3732ccb72323db81430f7c66ef 466 SMART SM00885 47 181 4.6E-4 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CPF12_RS08260 9df6fa3732ccb72323db81430f7c66ef 466 Gene3D G3DSA:3.40.50.300 159 361 8.1E-13 T 28-03-2018 CPF12_RS08260 9df6fa3732ccb72323db81430f7c66ef 466 Pfam PF08706 D5 N terminal like 129 179 2.5E-7 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SUPERFAMILY SSF47781 395 576 3.04E-64 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SUPERFAMILY SSF50249 310 392 1.39E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:2.40.50.140 314 382 2.2E-31 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SMART SM00292 588 665 1.8E-13 T 28-03-2018 IPR001357 BRCT domain CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:3.30.470.30 115 232 5.7E-46 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Hamap MF_01588 DNA ligase [ligA]. 1 662 52.289 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:3.40.50.10190 609 665 7.5E-17 T 28-03-2018 IPR001357 BRCT domain CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 314 390 9.9E-34 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SUPERFAMILY SSF52113 588 659 4.8E-18 T 28-03-2018 IPR001357 BRCT domain CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Pfam PF14520 Helix-hairpin-helix domain 439 491 0.0025 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 587 656 4.7E-14 T 28-03-2018 IPR001357 BRCT domain CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 8 658 4.8E-257 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Pfam PF12826 Helix-hairpin-helix motif 502 564 3.8E-25 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:1.10.150.20 494 542 8.0E-22 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:1.10.287.610 1 64 2.8E-21 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 PIRSF PIRSF001604 1 667 5.2E-249 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:1.10.150.20 543 608 8.6E-9 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 310 4.2E-121 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 399 425 3.5E-9 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SUPERFAMILY SSF56091 2 310 8.1E-117 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SMART SM00278 535 554 150.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SMART SM00278 437 456 43.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SMART SM00278 471 490 3.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 323 338 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 SMART SM00532 3 439 3.2E-254 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:1.10.150.20 423 493 5.3E-27 T 28-03-2018 CPF12_RS08740 b8a50f3c1778b036d3926905ccc32b01 670 Gene3D G3DSA:3.30.1490.70 233 313 2.1E-25 T 28-03-2018 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.1E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 SMART SM00354 1 71 2.2E-30 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 SUPERFAMILY SSF53822 59 325 2.78E-44 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 SUPERFAMILY SSF47413 1 59 1.6E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 Gene3D G3DSA:1.10.260.40 2 54 2.5E-21 T 28-03-2018 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 Gene3D G3DSA:3.40.50.2300 55 181 4.5E-29 T 28-03-2018 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 Gene3D G3DSA:3.40.50.2300 182 329 5.6E-22 T 28-03-2018 CPF12_RS00930 49ff1c0055c6fdaff8a24c7345ca0d04 329 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 326 1.8E-22 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 Gene3D G3DSA:2.20.150.10 9 42 3.2E-17 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 4.6E-111 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 PIRSF PIRSF000535 1 303 1.2E-91 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 Gene3D G3DSA:3.40.1190.20 43 304 2.0E-43 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 3.8E-110 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 SUPERFAMILY SSF53613 1 301 3.74E-67 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS07985 af214d9c5ba5d63dfe24a1e8f1d72681 307 Pfam PF00294 pfkB family carbohydrate kinase 11 282 1.4E-51 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 SMART SM00028 463 496 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 SMART SM00028 429 462 62.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 SUPERFAMILY SSF144091 176 358 4.05E-43 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 Gene3D G3DSA:1.25.40.10 393 506 9.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 Pfam PF13414 TPR repeat 436 477 5.3E-11 T 28-03-2018 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 Gene3D G3DSA:1.20.1540.10 179 358 2.8E-37 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 SUPERFAMILY SSF48452 404 492 6.24E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS01635 467c9e89ba8619c812c400b4cb75d4d8 509 Pfam PF01694 Rhomboid family 222 357 8.3E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CPF12_RS05645 88e21962715bceab6fc1a57f187bf769 106 Gene3D G3DSA:3.30.1310.10 1 106 5.8E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CPF12_RS05645 88e21962715bceab6fc1a57f187bf769 106 PIRSF PIRSF004555 3 106 8.5E-37 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CPF12_RS05645 88e21962715bceab6fc1a57f187bf769 106 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 105 4.5E-30 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CPF12_RS05645 88e21962715bceab6fc1a57f187bf769 106 SUPERFAMILY SSF82607 11 105 1.2E-31 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CPF12_RS05645 88e21962715bceab6fc1a57f187bf769 106 Pfam PF02575 YbaB/EbfC DNA-binding family 11 101 8.2E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CPF12_RS05645 88e21962715bceab6fc1a57f187bf769 106 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 21.598 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CPF12_RS06510 8af8cd8d5ddef0ea1d4a9dcac223128d 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 9.1E-109 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS06510 8af8cd8d5ddef0ea1d4a9dcac223128d 433 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 415 1.2E-172 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS06510 8af8cd8d5ddef0ea1d4a9dcac223128d 433 Gene3D G3DSA:3.65.10.10 21 218 1.0E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS06510 8af8cd8d5ddef0ea1d4a9dcac223128d 433 Gene3D G3DSA:3.65.10.10 219 419 1.8E-44 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS06510 8af8cd8d5ddef0ea1d4a9dcac223128d 433 SUPERFAMILY SSF55205 2 418 2.88E-136 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CPF12_RS06510 8af8cd8d5ddef0ea1d4a9dcac223128d 433 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 43.834 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 SUPERFAMILY SSF160996 193 361 3.79E-45 T 28-03-2018 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.7E-7 T 28-03-2018 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 1.7E-7 T 28-03-2018 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 Pfam PF03486 HI0933-like protein 3 412 1.3E-142 T 28-03-2018 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 SUPERFAMILY SSF51905 2 194 6.63E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 SUPERFAMILY SSF51905 358 415 6.63E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 390 9.2E-6 T 28-03-2018 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 9.2E-6 T 28-03-2018 CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 412 1.6E-133 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CPF12_RS09205 d0c95f76e31f74cc9170b7de0a0642c7 431 Gene3D G3DSA:3.50.50.60 1 420 1.0E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS01845 83a99c5743c57e364a46fb916b2c87ea 173 Pfam PF00156 Phosphoribosyl transferase domain 40 151 3.6E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CPF12_RS01845 83a99c5743c57e364a46fb916b2c87ea 173 SUPERFAMILY SSF53271 5 169 2.88E-52 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS01845 83a99c5743c57e364a46fb916b2c87ea 173 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 6 173 6.5E-73 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CPF12_RS01845 83a99c5743c57e364a46fb916b2c87ea 173 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 6 173 39.079 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CPF12_RS01845 83a99c5743c57e364a46fb916b2c87ea 173 Gene3D G3DSA:3.40.50.2020 1 172 1.0E-41 T 28-03-2018 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Gene3D G3DSA:3.30.1480.10 1 129 1.0E-48 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SMART SM00316 133 199 2.8E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 396 30.304 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Gene3D G3DSA:2.40.50.140 136 197 1.3E-13 T 28-03-2018 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Pfam PF13184 NusA-like KH domain 229 296 5.1E-29 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SUPERFAMILY SSF69705 1 126 2.22E-42 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SMART SM00322 300 380 4.1E-5 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SMART SM00322 229 292 1.5 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SUPERFAMILY SSF54814 199 277 2.29E-30 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Gene3D G3DSA:3.30.300.20 277 347 4.5E-17 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 6.7E-129 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Gene3D G3DSA:3.30.300.20 198 275 1.1E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SUPERFAMILY SSF50249 132 198 2.54E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 SUPERFAMILY SSF54814 278 340 1.7E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Pfam PF08529 NusA N-terminal domain 4 123 1.2E-42 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CPF12_RS12195 f096961b54c8a79e1e7d33dc70c1371f 397 Pfam PF00575 S1 RNA binding domain 133 195 6.0E-9 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS11990 3d5cf04df39a4ce60412f18697f66180 216 Gene3D G3DSA:1.10.340.30 27 125 3.0E-17 T 28-03-2018 CPF12_RS11990 3d5cf04df39a4ce60412f18697f66180 216 SUPERFAMILY SSF48150 8 203 4.24E-40 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CPF12_RS11990 3d5cf04df39a4ce60412f18697f66180 216 PIRSF PIRSF001435 3 214 9.8E-49 T 28-03-2018 CPF12_RS11990 3d5cf04df39a4ce60412f18697f66180 216 SMART SM00478 39 196 3.4E-16 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS11990 3d5cf04df39a4ce60412f18697f66180 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 168 9.2E-11 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS11990 3d5cf04df39a4ce60412f18697f66180 216 Gene3D G3DSA:1.10.1670.10 126 210 7.0E-10 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CPF12_RS09535 05b21e289df46e510c39657457330705 368 Gene3D G3DSA:1.10.3660.10 183 296 7.6E-25 T 28-03-2018 CPF12_RS09535 05b21e289df46e510c39657457330705 368 Pfam PF02153 Prephenate dehydrogenase 17 274 1.3E-74 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CPF12_RS09535 05b21e289df46e510c39657457330705 368 Gene3D G3DSA:3.40.50.720 1 173 7.7E-27 T 28-03-2018 CPF12_RS09535 05b21e289df46e510c39657457330705 368 SUPERFAMILY SSF48179 176 283 6.8E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS09535 05b21e289df46e510c39657457330705 368 SUPERFAMILY SSF51735 4 169 4.31E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09535 05b21e289df46e510c39657457330705 368 Gene3D G3DSA:3.30.70.260 297 363 9.3E-7 T 28-03-2018 CPF12_RS09535 05b21e289df46e510c39657457330705 368 SUPERFAMILY SSF55021 290 358 2.7E-7 T 28-03-2018 CPF12_RS00435 0cd89bee0d832333d7a10f8073f9f101 395 Gene3D G3DSA:3.20.20.300 53 394 1.3E-67 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS00435 0cd89bee0d832333d7a10f8073f9f101 395 SUPERFAMILY SSF51445 55 392 3.58E-67 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS00435 0cd89bee0d832333d7a10f8073f9f101 395 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 70 383 2.3E-63 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CPF12_RS00435 0cd89bee0d832333d7a10f8073f9f101 395 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 306 323 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CPF12_RS00605 7d45250671175095d81ebdf98b0a3c28 175 Pfam PF03729 Short repeat of unknown function (DUF308) 133 173 8.3E-6 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CPF12_RS00605 7d45250671175095d81ebdf98b0a3c28 175 Pfam PF03729 Short repeat of unknown function (DUF308) 14 86 2.5E-11 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CPF12_RS00605 7d45250671175095d81ebdf98b0a3c28 175 Pfam PF03729 Short repeat of unknown function (DUF308) 72 144 1.4E-10 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 PIRSF PIRSF001467 35 170 1.1E-38 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 PIRSF PIRSF001467 189 240 1.1E-7 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 SUPERFAMILY SSF50891 190 238 3.51E-57 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 SUPERFAMILY SSF50891 60 162 3.51E-57 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 62 237 2.2E-49 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 Gene3D G3DSA:2.40.100.10 27 240 7.3E-66 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 143 158 2.1E-16 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 113 2.1E-16 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS11885 c0ddba62ebedb825c35aadc5bec4d865 240 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 75 90 2.1E-16 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 Pfam PF16360 GTP-binding GTPase Middle Region 108 189 1.2E-27 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 Gene3D G3DSA:3.40.50.300 27 264 3.6E-11 T 28-03-2018 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 197 217 3.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 272 290 3.4E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 PIRSF PIRSF006809 1 416 2.7E-139 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 4 359 1.9E-126 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 Pfam PF01926 50S ribosome-binding GTPase 197 323 4.4E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 SUPERFAMILY SSF52540 196 365 2.07E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 Pfam PF13167 GTP-binding GTPase N-terminal 19 106 1.9E-29 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 Gene3D G3DSA:1.20.120.430 267 387 1.3E-14 T 28-03-2018 CPF12_RS07015 8b8b9127cf244b09c2fadb175b86803c 418 Hamap MF_00900 GTPase HflX [hflX]. 21 389 44.19 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Gene3D G3DSA:1.10.150.20 81 142 1.0E-11 T 28-03-2018 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Gene3D G3DSA:2.40.50.140 1 50 1.9E-21 T 28-03-2018 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Pfam PF14520 Helix-hairpin-helix domain 71 128 3.4E-13 T 28-03-2018 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Pfam PF07499 RuvA, C-terminal domain 150 194 2.9E-11 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 SUPERFAMILY SSF46929 149 194 1.31E-7 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 SMART SM00278 72 91 3.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 SMART SM00278 107 126 0.51 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Gene3D G3DSA:1.10.340.30 51 80 0.51 T 28-03-2018 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 SUPERFAMILY SSF50249 1 62 8.57E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Pfam PF01330 RuvA N terminal domain 1 61 3.0E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 28.188 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 192 1.6E-52 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 SUPERFAMILY SSF47781 65 135 1.45E-18 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS01885 bd606ed5927e1c48bca557deca0c2e13 196 Gene3D G3DSA:1.10.8.10 143 195 7.1E-9 T 28-03-2018 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 SMART SM00354 2 72 6.6E-35 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 Gene3D G3DSA:3.40.50.2300 172 305 8.4E-32 T 28-03-2018 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 Gene3D G3DSA:1.10.260.40 3 55 2.6E-20 T 28-03-2018 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 SUPERFAMILY SSF53822 60 312 7.57E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 1.1E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 SUPERFAMILY SSF47413 3 60 2.66E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 Gene3D G3DSA:3.40.50.2300 56 171 4.1E-32 T 28-03-2018 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07865 ace2892e77048a694b1f3a9b038b36e1 326 Pfam PF13377 Periplasmic binding protein-like domain 165 326 6.9E-28 T 28-03-2018 CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 Gene3D G3DSA:3.40.50.300 12 179 3.6E-33 T 28-03-2018 CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 PIRSF PIRSF006230 1 281 8.1E-99 T 28-03-2018 IPR016478 GTPase, MTG1 CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 Gene3D G3DSA:1.10.1580.10 180 279 6.3E-20 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 SUPERFAMILY SSF52540 9 208 2.57E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 Pfam PF01926 50S ribosome-binding GTPase 123 207 4.7E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 6.1E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 6.1E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS11795 bf6c3ca7aad2ad5f60a686f25e2c7749 298 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 276 1.8E-108 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CPF12_RS01625 9e82bcbead97b02fd865d7046c2464df 321 SUPERFAMILY SSF53067 4 319 6.04E-66 T 28-03-2018 CPF12_RS01625 9e82bcbead97b02fd865d7046c2464df 321 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 320 1.2E-100 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CPF12_RS01625 9e82bcbead97b02fd865d7046c2464df 321 ProSitePatterns PS01125 ROK family signature. 139 166 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS01625 9e82bcbead97b02fd865d7046c2464df 321 Gene3D G3DSA:3.30.420.40 125 321 3.3E-58 T 28-03-2018 CPF12_RS01625 9e82bcbead97b02fd865d7046c2464df 321 Gene3D G3DSA:3.30.420.40 3 124 4.8E-29 T 28-03-2018 CPF12_RS01625 9e82bcbead97b02fd865d7046c2464df 321 Pfam PF00480 ROK family 6 319 6.9E-72 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SUPERFAMILY SSF52440 1 127 2.01E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:3.30.470.20 738 927 1.6E-37 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.137 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SMART SM01209 674 837 0.0012 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:1.10.1030.10 402 531 1.2E-48 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:3.40.50.1380 928 1057 7.1E-34 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 7.7E-79 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 667 866 4.9E-38 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SUPERFAMILY SSF52440 549 668 8.2E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SUPERFAMILY SSF56059 666 926 2.65E-100 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SMART SM00851 949 1036 2.9E-24 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SUPERFAMILY SSF56059 128 399 2.83E-108 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:3.30.470.20 120 401 4.0E-66 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SUPERFAMILY SSF48108 394 547 4.97E-48 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SUPERFAMILY SSF52335 929 1050 4.45E-32 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:3.30.1490.20 648 737 1.3E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:3.40.50.20 532 647 2.4E-58 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Gene3D G3DSA:3.40.50.20 4 117 2.1E-38 T 28-03-2018 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.7E-65 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 2.3E-40 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 SMART SM01096 420 540 2.1E-63 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1058 13.3 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11335 092ee369bbc2bfe9b76e1adfd9990158 1058 Pfam PF02142 MGS-like domain 950 1036 3.7E-17 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 Gene3D G3DSA:3.40.630.30 130 275 1.4E-34 T 28-03-2018 CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 Gene3D G3DSA:3.30.1050.10 276 383 1.5E-19 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 Pfam PF13527 Acetyltransferase (GNAT) domain 5 124 8.8E-31 T 28-03-2018 CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 Pfam PF13530 Sterol carrier protein domain 175 361 1.0E-42 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 SUPERFAMILY SSF55718 283 388 2.2E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 Gene3D G3DSA:3.40.630.30 1 129 8.1E-11 T 28-03-2018 CPF12_RS04130 a95ef32d9e3847b07e73b099a075bdde 388 SUPERFAMILY SSF55729 1 282 3.42E-61 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS04210 e4bfb83928f4347456c9c685ec24bde9 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 24 269 9.5E-108 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CPF12_RS04210 e4bfb83928f4347456c9c685ec24bde9 272 Gene3D G3DSA:3.40.50.1580 1 272 2.4E-72 T 28-03-2018 CPF12_RS04210 e4bfb83928f4347456c9c685ec24bde9 272 PIRSF PIRSF000477 1 272 4.6E-113 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CPF12_RS04210 e4bfb83928f4347456c9c685ec24bde9 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 270 5.6E-109 T 28-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CPF12_RS04210 e4bfb83928f4347456c9c685ec24bde9 272 SUPERFAMILY SSF53167 4 271 1.83E-96 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS04210 e4bfb83928f4347456c9c685ec24bde9 272 Pfam PF01048 Phosphorylase superfamily 23 270 3.6E-55 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 PIRSF PIRSF001220 1 330 3.9E-83 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 Gene3D G3DSA:3.40.50.40 206 333 2.9E-30 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 PIRSF PIRSF500176 1 328 1.5E-92 T 28-03-2018 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 Pfam PF00710 Asparaginase, N-terminal 2 188 2.1E-58 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 2 331 2.3E-99 T 28-03-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 SMART SM00870 2 319 2.6E-101 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 82 92 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 PRINTS PR00139 Asparaginase/glutaminase family signature 81 99 1.2E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 1.2E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 PRINTS PR00139 Asparaginase/glutaminase family signature 256 274 1.2E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 5 13 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 Gene3D G3DSA:3.40.50.1170 1 205 1.0E-59 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CPF12_RS04375 c803cf0a03f43857ae15cb91b3994047 340 SUPERFAMILY SSF53774 2 335 8.11E-93 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 Gene3D G3DSA:3.40.50.1100 38 141 3.3E-40 T 28-03-2018 CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 Gene3D G3DSA:3.40.50.1100 142 307 1.6E-53 T 28-03-2018 CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 291 1.2E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 SUPERFAMILY SSF53686 2 304 3.27E-99 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 304 2.4E-135 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CPF12_RS05825 1e1a61ae0272e1f9ed1a329caaa24f2c 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 304 2.8E-128 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CPF12_RS12275 f2230e0bae1a8e76cd0ead2aaaa31dff 105 Gene3D G3DSA:3.30.70.240 1 103 4.6E-14 T 28-03-2018 CPF12_RS12275 f2230e0bae1a8e76cd0ead2aaaa31dff 105 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 96 12.997 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CPF12_RS12275 f2230e0bae1a8e76cd0ead2aaaa31dff 105 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 94 1.9E-18 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CPF12_RS12275 f2230e0bae1a8e76cd0ead2aaaa31dff 105 SUPERFAMILY SSF143430 1 85 8.04E-12 T 28-03-2018 CPF12_RS12275 f2230e0bae1a8e76cd0ead2aaaa31dff 105 Pfam PF09827 CRISPR associated protein Cas2 1 83 3.3E-16 T 28-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CPF12_RS11970 48c417fdad4244a3afac86c5c11fc763 436 Pfam PF14501 GHKL domain 336 427 4.9E-15 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CPF12_RS11970 48c417fdad4244a3afac86c5c11fc763 436 Gene3D G3DSA:1.10.287.130 231 289 5.3E-7 T 28-03-2018 CPF12_RS11970 48c417fdad4244a3afac86c5c11fc763 436 Gene3D G3DSA:3.30.565.10 293 411 4.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11970 48c417fdad4244a3afac86c5c11fc763 436 SUPERFAMILY SSF55874 297 417 2.23E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 31.334 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 PIRSF PIRSF002191 1 114 8.2E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 6.5E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 Pfam PF01245 Ribosomal protein L19 3 111 3.5E-52 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11645 07feca80fb1d32662cb75555128b4ee9 114 SUPERFAMILY SSF50104 1 113 2.81E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 SUPERFAMILY SSF46785 3 74 1.48E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 Gene3D G3DSA:3.90.1150.10 306 443 7.2E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 SMART SM00345 7 66 7.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 SUPERFAMILY SSF53383 77 442 1.03E-69 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 Pfam PF00155 Aminotransferase class I and II 111 404 1.0E-25 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.5E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 Gene3D G3DSA:1.10.10.10 2 68 8.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12135 e2287cd2b2794daade7f19698d12c4c2 449 Gene3D G3DSA:3.40.640.10 100 305 3.4E-26 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS04645 807e8faf516c9b7eb6312192f5830f23 196 SMART SM00047 41 193 4.2E-36 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS04645 807e8faf516c9b7eb6312192f5830f23 196 Gene3D G3DSA:1.10.530.10 41 191 5.2E-39 T 28-03-2018 CPF12_RS04645 807e8faf516c9b7eb6312192f5830f23 196 PRINTS PR01002 Flagellar protein FlgJ signature 71 89 6.3E-6 T 28-03-2018 CPF12_RS04645 807e8faf516c9b7eb6312192f5830f23 196 PRINTS PR01002 Flagellar protein FlgJ signature 170 188 6.3E-6 T 28-03-2018 CPF12_RS04645 807e8faf516c9b7eb6312192f5830f23 196 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 59 188 1.9E-24 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS00035 afd7f903823bbd1479dbcaa2f5d290b5 429 SUPERFAMILY SSF63411 247 412 4.54E-22 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS00035 afd7f903823bbd1479dbcaa2f5d290b5 429 Gene3D G3DSA:3.30.830.10 5 230 8.7E-15 T 28-03-2018 CPF12_RS00035 afd7f903823bbd1479dbcaa2f5d290b5 429 Pfam PF05193 Peptidase M16 inactive domain 185 358 9.0E-17 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CPF12_RS00035 afd7f903823bbd1479dbcaa2f5d290b5 429 SUPERFAMILY SSF63411 27 227 7.33E-15 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS00035 afd7f903823bbd1479dbcaa2f5d290b5 429 Gene3D G3DSA:3.30.830.10 231 415 2.1E-18 T 28-03-2018 CPF12_RS04665 4340a4e09980c64f2326173209a18488 339 Pfam PF00480 ROK family 108 240 8.6E-11 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS04665 4340a4e09980c64f2326173209a18488 339 SUPERFAMILY SSF46785 8 73 4.26E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04665 4340a4e09980c64f2326173209a18488 339 SUPERFAMILY SSF53067 101 291 2.54E-12 T 28-03-2018 CPF12_RS04665 4340a4e09980c64f2326173209a18488 339 Gene3D G3DSA:3.30.420.40 190 252 6.5E-8 T 28-03-2018 CPF12_RS04665 4340a4e09980c64f2326173209a18488 339 Gene3D G3DSA:3.30.420.40 88 189 5.6E-7 T 28-03-2018 CPF12_RS10280 ca47e6252f584de61fdb69eeb5d4fcb3 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 9.6E-20 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CPF12_RS10280 ca47e6252f584de61fdb69eeb5d4fcb3 109 SUPERFAMILY SSF101386 5 104 2.78E-26 T 28-03-2018 CPF12_RS10280 ca47e6252f584de61fdb69eeb5d4fcb3 109 Gene3D G3DSA:1.10.3420.10 2 109 2.8E-26 T 28-03-2018 CPF12_RS10280 ca47e6252f584de61fdb69eeb5d4fcb3 109 PIRSF PIRSF029904 1 109 1.5E-50 T 28-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 SUPERFAMILY SSF56784 1 205 3.05E-45 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 Gene3D G3DSA:1.10.150.240 14 81 2.8E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 1 189 7.3E-76 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 Gene3D G3DSA:3.40.50.1000 82 212 1.8E-22 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 89 188 2.1E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 188 7.3E-21 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS00910 669287d07f896a2d803e8ec079766890 222 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 1 188 4.0E-59 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CPF12_RS10510 32e4f987183c6db8fec85ab7d1f19cbf 193 SUPERFAMILY SSF53271 2 190 6.59E-40 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS10510 32e4f987183c6db8fec85ab7d1f19cbf 193 Gene3D G3DSA:3.40.50.2020 3 188 7.3E-17 T 28-03-2018 CPF12_RS10510 32e4f987183c6db8fec85ab7d1f19cbf 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 3 189 5.9E-79 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CPF12_RS10510 32e4f987183c6db8fec85ab7d1f19cbf 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 39.983 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CPF12_RS04455 dca22ff4707931f5324e16d7acad9825 180 SUPERFAMILY SSF46689 6 69 1.04E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS04455 dca22ff4707931f5324e16d7acad9825 180 Gene3D G3DSA:1.10.10.60 6 48 2.3E-11 T 28-03-2018 CPF12_RS04455 dca22ff4707931f5324e16d7acad9825 180 Gene3D G3DSA:1.10.10.60 49 133 1.4E-6 T 28-03-2018 CPF12_RS04455 dca22ff4707931f5324e16d7acad9825 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 59 3.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS09185 38ee48c3297b28b2e17e1cfe8cceca92 141 Gene3D G3DSA:3.40.630.30 1 136 1.2E-17 T 28-03-2018 CPF12_RS09185 38ee48c3297b28b2e17e1cfe8cceca92 141 SUPERFAMILY SSF55729 5 139 9.59E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS09185 38ee48c3297b28b2e17e1cfe8cceca92 141 Pfam PF13673 Acetyltransferase (GNAT) domain 46 139 1.5E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 SMART SM00448 2 116 1.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 SUPERFAMILY SSF52172 1 142 2.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 SUPERFAMILY SSF46689 386 435 4.48E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 SMART SM00342 401 484 2.1E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 438 480 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 Pfam PF00072 Response regulator receiver domain 5 116 3.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 453 468 7.4E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 468 484 7.4E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 SUPERFAMILY SSF46689 437 487 1.58E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 Gene3D G3DSA:1.10.10.60 434 491 5.1E-16 T 28-03-2018 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 Pfam PF12833 Helix-turn-helix domain 407 486 8.5E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 Gene3D G3DSA:3.40.50.2300 1 231 1.8E-32 T 28-03-2018 CPF12_RS00280 cde950b5ff951387d1b17f66cdf53df9 491 Gene3D G3DSA:1.10.10.60 375 433 7.7E-15 T 28-03-2018 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 Gene3D G3DSA:1.20.1080.10 1 243 1.5E-73 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 PRINTS PR00783 Major intrinsic protein family signature 7 26 8.8E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 PRINTS PR00783 Major intrinsic protein family signature 221 241 8.8E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 PRINTS PR00783 Major intrinsic protein family signature 86 105 8.8E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 PRINTS PR00783 Major intrinsic protein family signature 141 159 8.8E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 PRINTS PR00783 Major intrinsic protein family signature 49 73 8.8E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 PRINTS PR00783 Major intrinsic protein family signature 174 196 8.8E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 Pfam PF00230 Major intrinsic protein 7 238 1.6E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 SUPERFAMILY SSF81338 5 242 1.57E-64 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS08320 909ef13a2da8c8e6e906e182a8893cbd 243 ProSitePatterns PS00221 MIP family signature. 67 75 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 SUPERFAMILY SSF50193 2 122 7.33E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 3.2E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.996 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.4E-55 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 Gene3D G3DSA:2.40.150.20 1 122 1.8E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CPF12_RS06110 a063e8708a64db1f5144e6f05bbd901d 122 SMART SM01374 1 122 2.8E-82 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Gene3D G3DSA:3.40.120.10 158 264 3.3E-21 T 28-03-2018 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 SUPERFAMILY SSF55957 359 447 6.15E-27 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 371 7.1E-34 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 SUPERFAMILY SSF53738 160 258 2.83E-24 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 43.704 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 255 4.9E-15 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 1.1E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 1.1E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.1E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 443 2.3E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Gene3D G3DSA:3.40.120.10 1 154 4.1E-42 T 28-03-2018 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 2.0E-180 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 SUPERFAMILY SSF53738 259 368 5.1E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 SUPERFAMILY SSF53738 3 181 3.18E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Gene3D G3DSA:3.40.120.10 265 375 1.9E-34 T 28-03-2018 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 3.0E-41 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS03175 057de7f3f5ea23508c9fa65a13138653 449 Gene3D G3DSA:3.30.310.50 376 448 2.7E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CPF12_RS08400 707767e0b39795bb447c853411290698 232 Gene3D G3DSA:2.40.50.40 124 194 2.7E-13 T 28-03-2018 CPF12_RS08400 707767e0b39795bb447c853411290698 232 SMART SM00850 134 229 1.0E-10 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS08400 707767e0b39795bb447c853411290698 232 Pfam PF04397 LytTr DNA-binding domain 136 228 1.1E-15 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 SUPERFAMILY SSF55874 419 592 2.62E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 590 1.8E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 Pfam PF00672 HAMP domain 196 243 4.5E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 SMART SM00388 363 430 6.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 SMART SM00387 476 592 8.4E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 Gene3D G3DSA:3.30.450.20 240 359 5.8E-8 T 28-03-2018 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 Gene3D G3DSA:1.10.287.130 360 426 1.7E-16 T 28-03-2018 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 SUPERFAMILY SSF158472 196 244 1.28E-10 T 28-03-2018 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 Gene3D G3DSA:3.30.565.10 437 592 3.9E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 1.6E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 1.6E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 1.6E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 1.6E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 SMART SM00304 195 247 5.4E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 430 3.7E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS09420 7f3a6cd8946ef4db32269a41a2bba0c8 603 SUPERFAMILY SSF47384 349 430 1.59E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 Gene3D G3DSA:3.40.50.300 1 288 7.2E-51 T 28-03-2018 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 SUPERFAMILY SSF52540 4 232 1.46E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 Pfam PF12848 ABC transporter 226 300 2.2E-19 T 28-03-2018 IPR032781 ABC-transporter extension domain CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 SUPERFAMILY SSF52540 301 505 2.91E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 Pfam PF00005 ABC transporter 20 186 2.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 Pfam PF00005 ABC transporter 336 464 6.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 Gene3D G3DSA:3.40.50.300 289 518 5.6E-36 T 28-03-2018 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 SMART SM00382 28 231 1.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00690 c7d399a36b56c230b41f7958d3581078 521 SMART SM00382 343 509 1.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 3 495 1.6E-167 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 Gene3D G3DSA:1.10.1370.10 60 500 1.3E-36 T 28-03-2018 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 SUPERFAMILY SSF55486 12 495 1.71E-95 T 28-03-2018 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 229 245 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 380 397 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 246 265 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 334 353 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 293 309 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 403 424 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 447 465 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 149 169 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 266 285 1.1E-67 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS10440 522bec92e2edf1b448c3e2d279ed63d3 502 PIRSF PIRSF006615 3 501 3.4E-181 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Pfam PF00877 NlpC/P60 family 484 585 3.6E-33 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SUPERFAMILY SSF54106 233 276 4.84E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SUPERFAMILY SSF54106 310 353 2.22E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Gene3D G3DSA:3.10.350.10 298 378 1.1E-15 T 28-03-2018 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Gene3D G3DSA:3.10.350.10 379 461 3.0E-16 T 28-03-2018 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SMART SM00257 29 72 7.0E-15 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SMART SM00257 233 277 2.8E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SMART SM00257 77 120 1.1E-16 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SMART SM00257 310 354 1.2E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SMART SM00257 390 434 1.1E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Pfam PF01476 LysM domain 311 353 6.2E-12 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Pfam PF01476 LysM domain 391 433 7.7E-12 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Pfam PF01476 LysM domain 30 71 6.1E-15 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Pfam PF01476 LysM domain 78 120 5.3E-14 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Pfam PF01476 LysM domain 234 276 2.7E-12 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Gene3D G3DSA:3.10.350.10 76 121 2.5E-15 T 28-03-2018 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Gene3D G3DSA:3.10.350.10 227 297 4.3E-15 T 28-03-2018 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Gene3D G3DSA:3.10.350.10 23 75 9.8E-13 T 28-03-2018 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SUPERFAMILY SSF54106 30 71 2.09E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SUPERFAMILY SSF54001 464 588 1.96E-41 T 28-03-2018 CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SUPERFAMILY SSF54106 390 433 9.68E-10 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 SUPERFAMILY SSF54106 77 120 7.06E-11 T 28-03-2018 IPR018392 LysM domain CPF12_RS03370 4dade4e1cf787169b17ca43fcd6cf6e5 593 Gene3D G3DSA:3.90.1720.10 471 592 5.7E-38 T 28-03-2018 CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 Gene3D G3DSA:2.160.10.10 47 212 6.2E-39 T 28-03-2018 CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 PIRSF PIRSF000441 1 211 1.1E-74 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 2.1E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 8.9E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 SUPERFAMILY SSF51161 4 169 4.16E-53 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 2.1E-67 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CPF12_RS05950 0d9edc2af2f3b6b1f0c4f49f91fa5e18 212 Gene3D G3DSA:1.10.3130.10 1 46 1.1E-19 T 28-03-2018 CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 2 365 2.0E-168 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 SUPERFAMILY SSF51338 318 365 1.65E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 SUPERFAMILY SSF51338 1 52 1.65E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 Gene3D G3DSA:3.20.20.140 64 316 1.4E-39 T 28-03-2018 CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 PIRSF PIRSF039004 1 368 5.3E-137 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 Pfam PF01979 Amidohydrolase family 48 354 1.8E-13 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 Gene3D G3DSA:2.30.40.10 1 63 1.1E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS10840 b0c147f59549135a396b985e54f91d80 368 SUPERFAMILY SSF51556 52 317 1.63E-71 T 28-03-2018 IPR032466 Metal-dependent hydrolase CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 PIRSF PIRSF037215 1 406 1.9E-190 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 Hamap MF_00550 Peptidase T [pepT]. 2 404 56.893 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 404 2.2E-189 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 Pfam PF07687 Peptidase dimerisation domain 207 305 6.8E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 SUPERFAMILY SSF53187 2 210 1.48E-79 T 28-03-2018 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 SUPERFAMILY SSF53187 322 406 1.48E-79 T 28-03-2018 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 Pfam PF01546 Peptidase family M20/M25/M40 139 402 3.4E-13 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 SUPERFAMILY SSF55031 209 320 5.02E-39 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 177 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CPF12_RS09820 b120ff4e3d485b6616015f7068966844 406 Gene3D G3DSA:3.40.630.10 1 406 7.0E-52 T 28-03-2018 CPF12_RS06895 0d10961ffa4e598cf2d0c013c6e767c1 341 Gene3D G3DSA:3.40.50.1360 95 341 1.3E-34 T 28-03-2018 CPF12_RS06895 0d10961ffa4e598cf2d0c013c6e767c1 341 SUPERFAMILY SSF100950 96 340 8.12E-62 T 28-03-2018 CPF12_RS06895 0d10961ffa4e598cf2d0c013c6e767c1 341 SUPERFAMILY SSF46785 19 84 1.74E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06895 0d10961ffa4e598cf2d0c013c6e767c1 341 Gene3D G3DSA:1.10.10.10 17 86 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06895 0d10961ffa4e598cf2d0c013c6e767c1 341 Pfam PF04198 Putative sugar-binding domain 91 340 2.6E-58 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 Pfam PF00557 Metallopeptidase family M24 11 239 5.6E-49 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 7.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 7.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 7.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 7.2E-18 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 4.9E-83 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 37.52 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 SUPERFAMILY SSF55920 1 247 2.75E-82 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS08370 53f14d3d2cea90265a072f224a9bb137 254 Gene3D G3DSA:3.90.230.10 1 249 9.6E-77 T 28-03-2018 CPF12_RS06980 a87af842d10519e8bc905fc85896660e 90 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 26 89 2.0E-17 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CPF12_RS06980 a87af842d10519e8bc905fc85896660e 90 Pfam PF01106 NifU-like domain 22 86 1.9E-23 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CPF12_RS06980 a87af842d10519e8bc905fc85896660e 90 Gene3D G3DSA:3.30.300.130 14 90 5.2E-23 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CPF12_RS06980 a87af842d10519e8bc905fc85896660e 90 SUPERFAMILY SSF117916 21 89 5.01E-22 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CPF12_RS04260 d934d121a4344b68ccefdb4ee8b21be8 384 Pfam PF01610 Transposase 137 360 3.6E-39 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS04260 d934d121a4344b68ccefdb4ee8b21be8 384 Gene3D G3DSA:1.10.260.40 113 178 3.4E-4 T 28-03-2018 CPF12_RS04260 d934d121a4344b68ccefdb4ee8b21be8 384 Gene3D G3DSA:1.10.10.10 74 112 5.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04260 d934d121a4344b68ccefdb4ee8b21be8 384 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 17 66 2.8E-10 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.8E-36 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.8E-36 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.8E-36 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.8E-36 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.586 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.4E-57 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.1E-47 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 Gene3D G3DSA:3.90.1170.10 2 139 6.1E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06095 80c0747d69afa08403ce30361bbae302 144 SUPERFAMILY SSF54686 1 137 6.15E-56 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06130 b6243fd58a16b7a868221fbe0972d2bc 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.638 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06130 b6243fd58a16b7a868221fbe0972d2bc 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06130 b6243fd58a16b7a868221fbe0972d2bc 132 SUPERFAMILY SSF56047 2 132 6.41E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06130 b6243fd58a16b7a868221fbe0972d2bc 132 Gene3D G3DSA:3.30.1370.30 1 67 9.4E-27 T 28-03-2018 CPF12_RS06130 b6243fd58a16b7a868221fbe0972d2bc 132 Pfam PF00410 Ribosomal protein S8 5 132 7.4E-54 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06130 b6243fd58a16b7a868221fbe0972d2bc 132 Gene3D G3DSA:3.30.1490.10 69 130 1.1E-23 T 28-03-2018 CPF12_RS11925 6eeed1fd88426a9fd13a7deea7045422 598 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11925 6eeed1fd88426a9fd13a7deea7045422 598 Pfam PF00005 ABC transporter 17 163 3.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11925 6eeed1fd88426a9fd13a7deea7045422 598 SUPERFAMILY SSF52540 3 213 2.72E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11925 6eeed1fd88426a9fd13a7deea7045422 598 Gene3D G3DSA:3.40.50.300 1 247 3.0E-61 T 28-03-2018 CPF12_RS11925 6eeed1fd88426a9fd13a7deea7045422 598 SMART SM00382 26 217 2.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02930 11a5f24e5d2a74d0e8f4b6f3c9c69e0d 171 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.748 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CPF12_RS02930 11a5f24e5d2a74d0e8f4b6f3c9c69e0d 171 PIRSF PIRSF029256 2 157 2.0E-65 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CPF12_RS02930 11a5f24e5d2a74d0e8f4b6f3c9c69e0d 171 SUPERFAMILY SSF75217 3 156 6.21E-42 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CPF12_RS02930 11a5f24e5d2a74d0e8f4b6f3c9c69e0d 171 Pfam PF00588 SpoU rRNA Methylase family 3 145 2.4E-32 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CPF12_RS02930 11a5f24e5d2a74d0e8f4b6f3c9c69e0d 171 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 1.0E-62 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CPF12_RS02930 11a5f24e5d2a74d0e8f4b6f3c9c69e0d 171 Gene3D G3DSA:3.40.1280.10 1 168 5.6E-40 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CPF12_RS09775 c216dab91ad188cab68480c138ccf466 181 SUPERFAMILY SSF53927 8 150 8.66E-39 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CPF12_RS09775 c216dab91ad188cab68480c138ccf466 181 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.6E-27 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CPF12_RS09775 c216dab91ad188cab68480c138ccf466 181 PIRSF PIRSF006019 1 149 2.8E-56 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CPF12_RS09775 c216dab91ad188cab68480c138ccf466 181 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 105 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CPF12_RS09775 c216dab91ad188cab68480c138ccf466 181 Gene3D G3DSA:3.40.140.10 3 144 2.9E-39 T 28-03-2018 CPF12_RS09775 c216dab91ad188cab68480c138ccf466 181 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 147 6.2E-79 T 28-03-2018 IPR013404 Competence operon E, ComEB CPF12_RS06830 c5b48a022d100b26a31fad841ad54f01 428 SUPERFAMILY SSF103473 22 421 6.28E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS06830 c5b48a022d100b26a31fad841ad54f01 428 Gene3D G3DSA:1.20.1250.20 10 214 4.6E-12 T 28-03-2018 CPF12_RS06830 c5b48a022d100b26a31fad841ad54f01 428 Pfam PF07690 Major Facilitator Superfamily 35 372 6.2E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS06830 c5b48a022d100b26a31fad841ad54f01 428 Gene3D G3DSA:1.20.1250.20 219 427 7.8E-15 T 28-03-2018 CPF12_RS10945 07a77973c88090cedc78fa57589fe805 236 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 113 131 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CPF12_RS10945 07a77973c88090cedc78fa57589fe805 236 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 222 2.3E-15 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CPF12_RS10945 07a77973c88090cedc78fa57589fe805 236 SUPERFAMILY SSF100950 1 234 2.7E-80 T 28-03-2018 CPF12_RS10945 07a77973c88090cedc78fa57589fe805 236 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 234 39.1 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CPF12_RS10945 07a77973c88090cedc78fa57589fe805 236 Gene3D G3DSA:3.40.50.1360 1 236 4.9E-65 T 28-03-2018 CPF12_RS00215 1355a54f06551e52df849b4f370d4504 464 Pfam PF12282 Signal transduction histidine kinase 6 139 4.6E-23 T 28-03-2018 IPR022066 Signal transduction histidine kinase CPF12_RS00215 1355a54f06551e52df849b4f370d4504 464 SUPERFAMILY SSF55874 339 458 2.05E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00215 1355a54f06551e52df849b4f370d4504 464 Gene3D G3DSA:3.30.565.10 252 458 6.8E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00215 1355a54f06551e52df849b4f370d4504 464 Pfam PF07568 Histidine kinase 270 342 4.3E-19 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CPF12_RS00215 1355a54f06551e52df849b4f370d4504 464 SMART SM00387 365 462 0.0093 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08360 834e23cfd9d4e5c634a3f67d07b09890 298 SUPERFAMILY SSF111331 4 296 1.46E-71 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CPF12_RS08360 834e23cfd9d4e5c634a3f67d07b09890 298 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 128 1.8E-33 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CPF12_RS08360 834e23cfd9d4e5c634a3f67d07b09890 298 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 295 1.9E-69 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CPF12_RS08360 834e23cfd9d4e5c634a3f67d07b09890 298 SMART SM00046 4 131 3.2E-7 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CPF12_RS08360 834e23cfd9d4e5c634a3f67d07b09890 298 Gene3D G3DSA:3.40.50.10330 1 132 3.5E-33 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CPF12_RS04500 a5d614b726213cc630e05d9d3a61cb9a 340 Pfam PF00296 Luciferase-like monooxygenase 21 300 1.3E-25 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS04500 a5d614b726213cc630e05d9d3a61cb9a 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 326 1.2E-89 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CPF12_RS04500 a5d614b726213cc630e05d9d3a61cb9a 340 SUPERFAMILY SSF51679 4 328 4.24E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS04500 a5d614b726213cc630e05d9d3a61cb9a 340 Gene3D G3DSA:3.20.20.30 10 334 7.7E-51 T 28-03-2018 CPF12_RS09960 721686a80f49320fae2b55b711d2247a 306 Pfam PF08338 Domain of unknown function (DUF1731) 257 302 9.2E-17 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CPF12_RS09960 721686a80f49320fae2b55b711d2247a 306 Gene3D G3DSA:3.40.50.720 1 306 5.8E-32 T 28-03-2018 CPF12_RS09960 721686a80f49320fae2b55b711d2247a 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 221 1.3E-13 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CPF12_RS09960 721686a80f49320fae2b55b711d2247a 306 SUPERFAMILY SSF51735 1 300 2.08E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09960 721686a80f49320fae2b55b711d2247a 306 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 300 7.5E-90 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 Gene3D G3DSA:1.10.10.60 2 43 1.8E-13 T 28-03-2018 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 Gene3D G3DSA:1.10.10.60 44 126 2.6E-6 T 28-03-2018 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 8.7E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 SUPERFAMILY SSF46689 2 74 1.23E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS03245 dbbe675ff25bb8ca37afa26892f33462 201 SUPERFAMILY SSF48498 82 188 2.93E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 Pfam PF00176 SNF2 family N-terminal domain 604 860 2.8E-48 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 SUPERFAMILY SSF52540 792 1031 5.32E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 Pfam PF08455 Bacterial SNF2 helicase associated 207 563 7.3E-35 T 28-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 SUPERFAMILY SSF52540 566 790 3.59E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 SMART SM00490 899 981 2.7E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 Gene3D G3DSA:3.40.50.10810 590 852 4.6E-42 T 28-03-2018 CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 Gene3D G3DSA:3.40.50.300 860 1019 1.5E-35 T 28-03-2018 CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 Pfam PF00271 Helicase conserved C-terminal domain 870 981 2.6E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS12360 a88eb2f65dfee6a0c06d4b31ef9ddf5e 1041 SMART SM00487 585 771 4.1E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS02975 c9b162c5eb9a85888624b372780630d6 222 Gene3D G3DSA:1.10.3720.10 2 222 1.4E-45 T 28-03-2018 CPF12_RS02975 c9b162c5eb9a85888624b372780630d6 222 SUPERFAMILY SSF161098 16 219 3.79E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02975 c9b162c5eb9a85888624b372780630d6 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 113 4.3E-29 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CPF12_RS02975 c9b162c5eb9a85888624b372780630d6 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 218 4.9E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 685 25.877 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 553 1.8E-201 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 1.0E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 1.0E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 314 330 1.0E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 1.0E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 1.0E-35 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 Pfam PF05746 DALR anticodon binding domain 586 678 7.6E-5 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 685 1.4E-225 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 Gene3D G3DSA:1.10.730.10 528 681 1.2E-5 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS11090 b2e885a64cd97fbb89df898fa3b21d87 688 SUPERFAMILY SSF109604 336 489 1.15E-14 T 28-03-2018 CPF12_RS00075 997e60f6a5a29467565dd3ff872d554d 106 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 20.893 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CPF12_RS00075 997e60f6a5a29467565dd3ff872d554d 106 Gene3D G3DSA:1.10.287.1080 1 94 6.8E-22 T 28-03-2018 CPF12_RS00075 997e60f6a5a29467565dd3ff872d554d 106 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 90 3.4E-17 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CPF12_RS00075 997e60f6a5a29467565dd3ff872d554d 106 SUPERFAMILY SSF101386 2 87 9.53E-25 T 28-03-2018 CPF12_RS00075 997e60f6a5a29467565dd3ff872d554d 106 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 4 87 1.1E-32 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CPF12_RS05785 ea135d48f7f843954843f6c0a1ce0465 525 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 357 500 1.1E-18 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CPF12_RS05785 ea135d48f7f843954843f6c0a1ce0465 525 Pfam PF01943 Polysaccharide biosynthesis protein 10 305 1.2E-33 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CPF12_RS05785 ea135d48f7f843954843f6c0a1ce0465 525 PIRSF PIRSF038958 4 516 1.4E-69 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CPF12_RS02920 f1cfc8d207ba69ef63f4432989f71b7d 206 Pfam PF01865 Protein of unknown function DUF47 6 203 4.9E-19 T 28-03-2018 IPR018445 Putative phosphate transport regulator CPF12_RS02920 f1cfc8d207ba69ef63f4432989f71b7d 206 Gene3D G3DSA:1.20.58.220 100 205 1.9E-8 T 28-03-2018 CPF12_RS02920 f1cfc8d207ba69ef63f4432989f71b7d 206 SUPERFAMILY SSF109755 7 198 3.01E-7 T 28-03-2018 CPF12_RS11295 f34e1f955e556d2b9dac5cf21cc5b341 279 Gene3D G3DSA:3.60.15.10 20 266 6.1E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11295 f34e1f955e556d2b9dac5cf21cc5b341 279 SUPERFAMILY SSF56281 28 277 5.5E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11295 f34e1f955e556d2b9dac5cf21cc5b341 279 SMART SM00849 38 234 1.5E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11295 f34e1f955e556d2b9dac5cf21cc5b341 279 Pfam PF00753 Metallo-beta-lactamase superfamily 36 228 1.6E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 SUPERFAMILY SSF48163 301 487 2.35E-48 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Gene3D G3DSA:1.10.10.350 392 489 7.1E-28 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 489 32.932 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 486 4.5E-180 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 6.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 213 221 6.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 197 207 6.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 6.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 6.5E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Gene3D G3DSA:3.40.50.620 5 131 8.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Gene3D G3DSA:1.10.1160.10 250 336 2.3E-29 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 SUPERFAMILY SSF52374 5 319 1.18E-103 T 28-03-2018 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Gene3D G3DSA:1.10.8.70 337 387 2.9E-4 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Gene3D G3DSA:3.40.50.620 132 249 8.2E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS05945 4ce8f6c99a2973d794ec132257338399 489 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 326 1.3E-117 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 5 271 9.9E-117 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 SUPERFAMILY SSF52096 17 267 7.46E-77 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 5 269 37.025 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 Gene3D G3DSA:3.90.226.10 3 273 1.3E-67 T 28-03-2018 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 239 248 5.0E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 217 228 5.0E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 151 169 5.0E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 117 131 5.0E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 188 205 5.0E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08430 afb96cf1b200bff3adf97945825de649 273 Pfam PF01039 Carboxyl transferase domain 51 229 6.0E-19 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 Pfam PF00005 ABC transporter 22 163 1.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 SUPERFAMILY SSF50331 238 367 5.1E-26 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 Gene3D G3DSA:2.40.50.140 297 352 2.8E-13 T 28-03-2018 CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 Gene3D G3DSA:2.40.50.100 241 296 2.5E-12 T 28-03-2018 CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 SMART SM00382 30 213 3.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 SUPERFAMILY SSF52540 5 245 3.25E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 Pfam PF08402 TOBE domain 285 359 3.8E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CPF12_RS00275 d68b06ea4d3cb9e99fcebec0b19e277a 368 Gene3D G3DSA:3.40.50.300 2 238 5.8E-69 T 28-03-2018 CPF12_RS10770 6733518b633af75c51e84d705a5c0296 454 Pfam PF03611 PTS system sugar-specific permease component 10 404 1.3E-130 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 SUPERFAMILY SSF51735 142 310 3.27E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 SMART SM00829 8 343 3.1E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 138 1.4E-22 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 SUPERFAMILY SSF50129 1 177 3.35E-43 T 28-03-2018 IPR011032 GroES-like CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 Pfam PF00107 Zinc-binding dehydrogenase 178 304 9.8E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 Gene3D G3DSA:3.40.50.720 171 289 2.3E-26 T 28-03-2018 CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 Gene3D G3DSA:3.90.180.10 1 170 2.1E-44 T 28-03-2018 CPF12_RS04370 5792b94acf450708d93f9f9f551959e7 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 480 4.0E-81 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 Pfam PF07690 Major Facilitator Superfamily 13 404 3.9E-58 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 Gene3D G3DSA:1.20.1250.20 247 494 1.4E-31 T 28-03-2018 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 SUPERFAMILY SSF103473 1 197 1.31E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 SUPERFAMILY SSF103473 463 488 1.31E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 SUPERFAMILY SSF103473 244 414 1.31E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 Gene3D G3DSA:1.20.1250.20 7 194 5.5E-39 T 28-03-2018 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 6.3E-6 T 28-03-2018 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 297 321 6.3E-6 T 28-03-2018 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 6.3E-6 T 28-03-2018 CPF12_RS05345 78a0a99258c9ee39404acdde22c22546 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 6.3E-6 T 28-03-2018 CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 Gene3D G3DSA:3.40.50.1000 2 29 0.3 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 Gene3D G3DSA:3.40.50.1000 86 213 1.4E-22 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 190 3.3E-17 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 3 191 6.3E-72 T 28-03-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 189 4.7E-19 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 SUPERFAMILY SSF56784 4 209 2.66E-42 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 4 190 7.3E-60 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CPF12_RS05260 64cef9561bdfcccac2adaf5fd5205924 214 Gene3D G3DSA:1.10.150.240 30 85 5.9E-16 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 SMART SM00642 141 507 1.5E-113 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 SUPERFAMILY SSF51445 67 510 5.28E-119 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 Gene3D G3DSA:3.20.20.470 117 241 7.1E-36 T 28-03-2018 CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 123 2.7E-35 T 28-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 Gene3D G3DSA:2.60.40.10 1 116 1.5E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 Gene3D G3DSA:3.20.20.80 295 515 4.8E-49 T 28-03-2018 CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 Pfam PF00128 Alpha amylase, catalytic domain 175 479 3.0E-80 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS07745 774b81d848372878d08269d51e0377f9 589 Gene3D G3DSA:3.90.400.10 249 294 6.0E-22 T 28-03-2018 CPF12_RS01565 b7ab8c1da6a3012400ed402224352819 486 Pfam PF02347 Glycine cleavage system P-protein 51 295 3.1E-8 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CPF12_RS01565 b7ab8c1da6a3012400ed402224352819 486 Gene3D G3DSA:3.40.640.10 83 344 3.8E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS01565 b7ab8c1da6a3012400ed402224352819 486 Gene3D G3DSA:3.90.1150.10 345 470 2.2E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS01565 b7ab8c1da6a3012400ed402224352819 486 SUPERFAMILY SSF53383 8 483 5.68E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS01565 b7ab8c1da6a3012400ed402224352819 486 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 58.267 T 28-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 454 1.1E-212 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 Gene3D G3DSA:3.30.499.10 1 154 1.1E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 SUPERFAMILY SSF53732 2 457 1.1E-160 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 Pfam PF00330 Aconitase family (aconitate hydratase) 8 448 6.9E-152 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 457 57.182 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 334 345 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 390 403 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 209 222 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 133 148 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 82 95 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 108 116 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 195 208 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 119 132 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 PRINTS PR00415 Aconitase family signature 284 298 1.2E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 Gene3D G3DSA:3.30.499.10 315 460 3.5E-47 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 ProSitePatterns PS01244 Aconitase family signature 2. 390 403 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 Gene3D G3DSA:3.40.1060.10 155 286 1.6E-42 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01920 5c70856a09ae557d06bc9c5109e1f10c 464 ProSitePatterns PS00450 Aconitase family signature 1. 330 346 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 SMART SM01091 352 429 6.2E-13 T 28-03-2018 IPR005170 Transporter-associated domain CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 SUPERFAMILY SSF54631 204 341 9.73E-29 T 28-03-2018 CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 Gene3D G3DSA:3.20.20.70 162 355 7.2E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 Pfam PF01595 Domain of unknown function DUF21 7 199 4.8E-44 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 Pfam PF03471 Transporter associated domain 354 428 4.0E-13 T 28-03-2018 IPR005170 Transporter-associated domain CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 SMART SM00116 225 275 2.0 T 28-03-2018 IPR000644 CBS domain CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 SMART SM00116 291 339 2.1 T 28-03-2018 IPR000644 CBS domain CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 Pfam PF00571 CBS domain 218 273 0.0016 T 28-03-2018 IPR000644 CBS domain CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 Pfam PF00571 CBS domain 292 339 1.1E-6 T 28-03-2018 IPR000644 CBS domain CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 SUPERFAMILY SSF56176 350 429 7.91E-12 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CPF12_RS08000 b7e9220dd56ba40c919b9495a23cf2e5 431 Gene3D G3DSA:3.30.465.10 356 429 2.0E-14 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CPF12_RS07780 6b61ebe8afe6c6064c2d48eadab4d310 410 Pfam PF01098 Cell cycle protein 15 377 6.0E-84 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CPF12_RS07780 6b61ebe8afe6c6064c2d48eadab4d310 410 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 336 360 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 759 33.784 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 Gene3D G3DSA:3.20.20.210 391 760 2.7E-114 T 28-03-2018 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 SUPERFAMILY SSF51726 7 388 8.63E-96 T 28-03-2018 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 SUPERFAMILY SSF51726 397 758 4.19E-108 T 28-03-2018 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 PIRSF PIRSF000382 3 761 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 314 5.0E-117 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 432 754 9.8E-142 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 758 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CPF12_RS03590 246ebe1a47cc92e8d1b2cd6e7c11721b 761 Gene3D G3DSA:3.20.20.210 4 390 1.4E-123 T 28-03-2018 CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 Gene3D G3DSA:3.40.50.720 41 247 4.1E-66 T 28-03-2018 CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 Gene3D G3DSA:3.40.50.720 1 40 2.7E-9 T 28-03-2018 CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 SUPERFAMILY SSF51735 5 246 6.63E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS07465 5867b8374b330e7d9cf6476ae731c0dd 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 9.5E-72 T 28-03-2018 CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 Gene3D G3DSA:1.10.12.10 213 261 7.1E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 TIGRFAM TIGR01929 menB: naphthoate synthase 12 269 1.5E-124 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 111 131 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 6 272 52.175 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 268 6.3E-81 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 Gene3D G3DSA:3.90.226.10 1 212 4.1E-59 T 28-03-2018 CPF12_RS10235 961b67f5bffe0853a36d15b1899e9030 273 SUPERFAMILY SSF52096 4 269 1.32E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CPF12_RS10255 f9497b3980ab176848f7fdc846e5d1d9 26 Pfam PF01610 Transposase 1 25 1.3E-8 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS07400 0b7ee3eab6b8914416377c51e7c9b4f9 78 Gene3D G3DSA:1.10.1200.10 1 77 5.9E-14 T 28-03-2018 CPF12_RS07400 0b7ee3eab6b8914416377c51e7c9b4f9 78 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 76 1.3E-31 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CPF12_RS07400 0b7ee3eab6b8914416377c51e7c9b4f9 78 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 78 48.161 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CPF12_RS07400 0b7ee3eab6b8914416377c51e7c9b4f9 78 SUPERFAMILY SSF47336 2 76 1.83E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS07400 0b7ee3eab6b8914416377c51e7c9b4f9 78 Pfam PF00550 Phosphopantetheine attachment site 6 68 8.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 PIRSF PIRSF006276 1 146 1.1E-20 T 28-03-2018 IPR006015 Universal stress protein A CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 SUPERFAMILY SSF52402 5 144 1.76E-36 T 28-03-2018 CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 PRINTS PR01438 Universal stress protein signature 5 23 6.0E-20 T 28-03-2018 IPR006015 Universal stress protein A CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 PRINTS PR01438 Universal stress protein signature 104 116 6.0E-20 T 28-03-2018 IPR006015 Universal stress protein A CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 PRINTS PR01438 Universal stress protein signature 122 144 6.0E-20 T 28-03-2018 IPR006015 Universal stress protein A CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 Gene3D G3DSA:3.40.50.620 2 150 1.2E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS08955 a358bebdc2cd1c839db8c4b4ea424413 153 Pfam PF00582 Universal stress protein family 5 144 9.7E-40 T 28-03-2018 IPR006016 UspA GO:0006950 CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 Pfam PF00294 pfkB family carbohydrate kinase 13 312 2.0E-66 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 Gene3D G3DSA:3.40.1190.20 45 325 4.2E-54 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 7 325 51.647 T 28-03-2018 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 Gene3D G3DSA:2.20.150.10 21 44 7.6E-14 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 10 321 2.7E-115 T 28-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CPF12_RS10975 30acf423a3786b23100a735d61048c6f 325 SUPERFAMILY SSF53613 9 321 1.14E-71 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS04770 12ba431378a0f4d39561571b58caec5b 209 Pfam PF04239 Protein of unknown function (DUF421) 89 189 1.4E-28 T 28-03-2018 IPR007353 Protein of unknown function DUF421 CPF12_RS04770 12ba431378a0f4d39561571b58caec5b 209 Gene3D G3DSA:3.30.240.20 156 209 5.8E-10 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CPF12_RS04770 12ba431378a0f4d39561571b58caec5b 209 Gene3D G3DSA:3.30.240.20 82 151 2.5E-17 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CPF12_RS09750 d320949e359a8e2823847ddcacfabc87 190 SUPERFAMILY SSF52374 1 188 2.44E-51 T 28-03-2018 CPF12_RS09750 d320949e359a8e2823847ddcacfabc87 190 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 188 3.9E-48 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CPF12_RS09750 d320949e359a8e2823847ddcacfabc87 190 Gene3D G3DSA:3.40.50.620 2 190 5.1E-47 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS09750 d320949e359a8e2823847ddcacfabc87 190 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 68 9.6E-13 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS09750 d320949e359a8e2823847ddcacfabc87 190 Pfam PF01467 Cytidylyltransferase-like 7 162 9.4E-29 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS09750 d320949e359a8e2823847ddcacfabc87 190 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 3 189 29.678 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CPF12_RS08365 43d9ba8f722f10dffeefa54eee306956 148 Pfam PF00258 Flavodoxin 6 131 1.3E-24 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CPF12_RS08365 43d9ba8f722f10dffeefa54eee306956 148 SUPERFAMILY SSF52218 1 146 1.02E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS08365 43d9ba8f722f10dffeefa54eee306956 148 TIGRFAM TIGR01753 flav_short: flavodoxin 5 142 9.0E-45 T 28-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CPF12_RS08365 43d9ba8f722f10dffeefa54eee306956 148 Gene3D G3DSA:3.40.50.360 1 148 3.5E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS09020 bcb19d61d77ac4e76c0c2668e804c4ce 485 PIRSF PIRSF026631 6 485 3.6E-78 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CPF12_RS09020 bcb19d61d77ac4e76c0c2668e804c4ce 485 Pfam PF03703 Bacterial PH domain 69 132 5.9E-8 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CPF12_RS09020 bcb19d61d77ac4e76c0c2668e804c4ce 485 Pfam PF03703 Bacterial PH domain 402 481 4.3E-7 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CPF12_RS09020 bcb19d61d77ac4e76c0c2668e804c4ce 485 Pfam PF03703 Bacterial PH domain 269 333 3.5E-8 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CPF12_RS09895 a41b4248166c61daf9e496c2fc19bb04 242 Pfam PF04203 Sortase family 74 238 5.7E-19 T 28-03-2018 IPR005754 Sortase family CPF12_RS09895 a41b4248166c61daf9e496c2fc19bb04 242 PIRSF PIRSF030150 1 240 1.7E-90 T 28-03-2018 IPR015986 Sortase B, Firmicutes CPF12_RS09895 a41b4248166c61daf9e496c2fc19bb04 242 SUPERFAMILY SSF63817 11 240 1.83E-69 T 28-03-2018 IPR023365 Sortase domain CPF12_RS09895 a41b4248166c61daf9e496c2fc19bb04 242 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 4 234 1.2E-83 T 28-03-2018 IPR009835 Sortase B family CPF12_RS09895 a41b4248166c61daf9e496c2fc19bb04 242 Gene3D G3DSA:2.40.260.10 55 239 2.1E-63 T 28-03-2018 IPR023365 Sortase domain CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 SUPERFAMILY SSF101353 249 447 2.48E-67 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 SUPERFAMILY SSF55186 558 712 7.85E-51 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 Pfam PF01411 tRNA synthetases class II (A) 8 560 1.2E-203 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 SUPERFAMILY SSF50447 459 558 3.53E-15 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 881 175.075 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 Gene3D G3DSA:3.30.980.10 559 706 1.6E-44 T 28-03-2018 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 SUPERFAMILY SSF55681 5 248 7.95E-83 T 28-03-2018 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 Pfam PF02272 DHHA1 domain 740 879 1.5E-25 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 Gene3D G3DSA:3.30.930.10 3 245 2.0E-92 T 28-03-2018 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 SMART SM00863 659 702 7.5E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 1.2E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 1.2E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.2E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.2E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.2E-30 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 659 702 1.9E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CPF12_RS09675 c4136debd55115ea8d1f31aff1f3e9fd 881 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 862 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CPF12_RS01420 47cfecf4d18b80ae2b2b229cc03491f3 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 9.0E-15 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CPF12_RS01420 47cfecf4d18b80ae2b2b229cc03491f3 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 9.4E-25 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CPF12_RS05930 e3476fec7fb39c2db4699426796748d7 360 Gene3D G3DSA:3.40.50.1010 161 296 1.9E-28 T 28-03-2018 IPR029060 PIN domain-like CPF12_RS05930 e3476fec7fb39c2db4699426796748d7 360 SUPERFAMILY SSF88723 168 293 1.57E-23 T 28-03-2018 IPR029060 PIN domain-like CPF12_RS05930 e3476fec7fb39c2db4699426796748d7 360 SMART SM00670 165 272 1.3E-12 T 28-03-2018 IPR002716 PIN domain CPF12_RS03695 bdea37e386eb6e8876e44d6aeb33c404 116 Pfam PF13038 Domain of unknown function (DUF3899) 33 112 1.2E-14 T 28-03-2018 IPR025007 Domain of unknown function DUF3899 CPF12_RS10245 16e170b42873abacafc4e2ade5de950c 448 SUPERFAMILY SSF53623 41 192 6.93E-30 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS10245 16e170b42873abacafc4e2ade5de950c 448 SUPERFAMILY SSF53623 226 297 6.93E-30 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS10245 16e170b42873abacafc4e2ade5de950c 448 Gene3D G3DSA:3.40.1190.10 46 306 9.1E-37 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS10245 16e170b42873abacafc4e2ade5de950c 448 Pfam PF08353 Domain of unknown function (DUF1727) 321 431 8.0E-35 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CPF12_RS10245 16e170b42873abacafc4e2ade5de950c 448 Pfam PF08245 Mur ligase middle domain 54 224 1.5E-12 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS05380 93cb68f99453cf68ac7e080d3afd388d 179 Pfam PF00436 Single-strand binding protein family 2 103 6.6E-38 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CPF12_RS05380 93cb68f99453cf68ac7e080d3afd388d 179 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 179 2.7E-51 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CPF12_RS05380 93cb68f99453cf68ac7e080d3afd388d 179 Gene3D G3DSA:2.40.50.140 1 111 4.3E-42 T 28-03-2018 CPF12_RS05380 93cb68f99453cf68ac7e080d3afd388d 179 SUPERFAMILY SSF50249 1 179 2.33E-58 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS05380 93cb68f99453cf68ac7e080d3afd388d 179 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 36.783 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CPF12_RS05380 93cb68f99453cf68ac7e080d3afd388d 179 PIRSF PIRSF002070 1 168 3.0E-42 T 28-03-2018 CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 SUPERFAMILY SSF75217 1 237 1.57E-96 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 8.2E-96 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 PIRSF PIRSF000386 1 248 3.1E-100 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 Gene3D G3DSA:3.40.1280.10 1 168 4.7E-73 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 Gene3D G3DSA:1.10.1270.20 169 248 2.4E-33 T 28-03-2018 CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 2.8E-64 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CPF12_RS11640 02d08e0e44fb544c4c7f758fbf6104b3 249 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 249 107.096 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CPF12_RS04855 d67cd3cf4eb9f505b9c7f4af7a269586 231 SMART SM00850 134 229 3.5E-14 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS04855 d67cd3cf4eb9f505b9c7f4af7a269586 231 Gene3D G3DSA:2.40.50.40 127 193 1.3E-11 T 28-03-2018 CPF12_RS04855 d67cd3cf4eb9f505b9c7f4af7a269586 231 SUPERFAMILY SSF52172 2 118 1.74E-6 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS04855 d67cd3cf4eb9f505b9c7f4af7a269586 231 Pfam PF04397 LytTr DNA-binding domain 137 228 1.2E-11 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS04855 d67cd3cf4eb9f505b9c7f4af7a269586 231 Gene3D G3DSA:3.40.50.2300 1 124 1.6E-5 T 28-03-2018 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 SUPERFAMILY SSF46689 66 113 5.11E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 SUPERFAMILY SSF46689 117 165 5.82E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 Pfam PF12833 Helix-turn-helix domain 87 164 5.0E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 Gene3D G3DSA:3.90.1240.10 3 168 4.8E-33 T 28-03-2018 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 147 163 6.8E-8 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 132 147 6.8E-8 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CPF12_RS07325 55a324eadff2aa42f5080a08eb60d89c 168 SMART SM00342 80 163 9.8E-33 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 SUPERFAMILY SSF55347 151 317 2.5E-61 T 28-03-2018 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 2.2E-134 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 7.1E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 7.1E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 7.1E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 7.1E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 7.1E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 SUPERFAMILY SSF51735 3 167 1.1E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 Gene3D G3DSA:3.30.360.10 161 318 1.3E-57 T 28-03-2018 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.9E-37 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 PIRSF PIRSF000149 1 338 3.0E-121 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 Gene3D G3DSA:3.40.50.720 1 160 1.4E-75 T 28-03-2018 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 316 1.4E-60 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06900 60c5ef5d1034ef2ba168b031421f5b3d 338 SMART SM00846 3 151 5.3E-90 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 50.549 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 1.3E-45 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Gene3D G3DSA:2.40.30.20 3 82 5.0E-36 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 2.4E-19 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Gene3D G3DSA:1.20.150.20 373 498 1.6E-48 T 28-03-2018 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 SUPERFAMILY SSF52540 95 370 1.47E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 PIRSF PIRSF039088 1 501 1.2E-241 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 SUPERFAMILY SSF47917 372 499 1.75E-47 T 28-03-2018 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 2.3E-250 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.1E-70 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 SUPERFAMILY SSF50615 10 94 2.3E-29 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06485 15c2919cd4ef77c94e4b03f693427ae8 503 Gene3D G3DSA:3.40.50.300 83 364 5.0E-117 T 28-03-2018 CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 Gene3D G3DSA:2.40.50.140 2 80 2.5E-21 T 28-03-2018 CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 390 421 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 SUPERFAMILY SSF53335 73 456 1.2E-80 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 SUPERFAMILY SSF50249 8 66 6.85E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 Gene3D G3DSA:3.40.50.150 81 165 3.0E-11 T 28-03-2018 CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 Gene3D G3DSA:3.40.50.150 167 457 1.3E-46 T 28-03-2018 CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 95 457 2.9E-25 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 Pfam PF01938 TRAM domain 12 65 6.5E-14 T 28-03-2018 IPR002792 TRAM domain CPF12_RS08390 1ade9b9a97f061c6300d1a0c9550c94d 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 451 5.4E-163 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 SUPERFAMILY SSF51366 2 215 2.71E-79 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 1.1E-95 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 PIRSF PIRSF001461 1 217 9.2E-99 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 5.0E-88 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS11480 d96a5a0de6ceb214a55dc5826f9635ad 217 Gene3D G3DSA:3.20.20.70 1 217 2.1E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS07045 fcb60b7888c484951c744c5b38d728f8 448 Pfam PF00324 Amino acid permease 16 416 6.4E-94 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CPF12_RS07045 fcb60b7888c484951c744c5b38d728f8 448 PIRSF PIRSF006060 1 448 6.6E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CPF12_RS07045 fcb60b7888c484951c744c5b38d728f8 448 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 326 4.3E-149 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 Gene3D G3DSA:3.20.20.70 1 330 1.1E-151 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 246 258 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PIRSF PIRSF001415 2 330 1.2E-153 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 SMART SM01004 8 327 4.3E-233 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 246 262 3.9E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 156 175 3.9E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 194 213 3.9E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 301 320 3.9E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 271 286 3.9E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 126 140 3.9E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CPF12_RS12460 c6b187cd97081166432dcb75822bfcec 330 SUPERFAMILY SSF51569 5 329 4.54E-142 T 28-03-2018 CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 21 198 2.1E-56 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 SUPERFAMILY SSF110849 24 163 1.26E-33 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 Gene3D G3DSA:3.90.1530.10 15 114 3.4E-36 T 28-03-2018 CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 Gene3D G3DSA:1.10.10.730 115 162 2.6E-17 T 28-03-2018 CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 Pfam PF08535 KorB domain 137 174 2.9E-6 T 28-03-2018 IPR013741 Repressor KorB domain CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 SMART SM00470 25 114 3.5E-34 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS05440 ec0d116def0b407554e036aef2e75323 285 Pfam PF02195 ParB-like nuclease domain 26 113 7.5E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS05490 55d2ac51fa17a1df14d1f8f3db104239 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.346 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05490 55d2ac51fa17a1df14d1f8f3db104239 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.7E-19 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05490 55d2ac51fa17a1df14d1f8f3db104239 44 Pfam PF00468 Ribosomal protein L34 1 44 1.8E-22 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05490 55d2ac51fa17a1df14d1f8f3db104239 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-5 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06280 aec9e4ab0e92c47c81cf0bdfcb7a5e39 191 PIRSF PIRSF037394 1 190 1.6E-52 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CPF12_RS06280 aec9e4ab0e92c47c81cf0bdfcb7a5e39 191 Pfam PF09819 ABC-type cobalt transport system, permease component 8 125 2.5E-33 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 SMART SM00984 322 409 7.9E-17 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 PIRSF PIRSF500136 1 438 7.6E-143 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 12 185 1.5E-35 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 Gene3D G3DSA:3.40.50.720 229 437 4.4E-50 T 28-03-2018 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 SUPERFAMILY SSF48179 206 297 7.14E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 295 2.4E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 SUPERFAMILY SSF51735 12 197 1.54E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 Gene3D G3DSA:3.40.50.720 2 204 1.9E-40 T 28-03-2018 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 PIRSF PIRSF000124 11 438 3.5E-59 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 12 409 1.7E-115 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 323 407 4.5E-14 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 Gene3D G3DSA:1.20.5.170 206 228 1.6E-10 T 28-03-2018 CPF12_RS06580 804e522d399c42de2fd1073737b42492 438 SUPERFAMILY SSF52413 305 405 4.84E-20 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CPF12_RS02060 dc490807327bc1b9d0eec6845fac3b8a 59 SUPERFAMILY SSF57829 1 56 4.15E-22 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CPF12_RS02060 dc490807327bc1b9d0eec6845fac3b8a 59 Gene3D G3DSA:2.20.28.10 5 41 0.02 T 28-03-2018 CPF12_RS02060 dc490807327bc1b9d0eec6845fac3b8a 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 5.8E-27 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02060 dc490807327bc1b9d0eec6845fac3b8a 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.169 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02060 dc490807327bc1b9d0eec6845fac3b8a 59 Pfam PF01783 Ribosomal L32p protein family 2 56 1.3E-25 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 Gene3D G3DSA:3.30.70.920 54 149 7.8E-29 T 28-03-2018 CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 SUPERFAMILY SSF46785 1 61 5.81E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 Pfam PF01037 Lrp/AsnC ligand binding domain 68 139 1.7E-19 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 Gene3D G3DSA:1.10.10.10 1 52 6.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 SMART SM00344 1 108 2.1E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 SUPERFAMILY SSF54909 61 148 2.55E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11235 57d32af6c92441de3772cf625007a555 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 6.5E-14 T 28-03-2018 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 SUPERFAMILY SSF51395 2 299 1.04E-87 T 28-03-2018 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 302 40.984 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 Gene3D G3DSA:3.20.20.70 1 308 1.4E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 PIRSF PIRSF000164 1 302 5.1E-83 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 Pfam PF01180 Dihydroorotate dehydrogenase 4 287 1.5E-93 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 240 260 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CPF12_RS11345 c7ff77176ce03b908c3e69dbb5b133d5 308 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 299 7.0E-122 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 108 125 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 81 94 5.6E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 113 126 5.6E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 98 112 5.6E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 Pfam PF00364 Biotin-requiring enzyme 78 151 1.9E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 152 1.3E-51 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 Gene3D G3DSA:2.40.50.100 77 110 7.0E-7 T 28-03-2018 CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 SUPERFAMILY SSF51230 77 151 2.09E-23 T 28-03-2018 IPR011053 Single hybrid motif CPF12_RS01505 e4744b830c135c4a98e43a94c282271e 154 Gene3D G3DSA:2.40.50.100 111 154 4.4E-19 T 28-03-2018 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 SUPERFAMILY SSF54631 66 208 7.96E-30 T 28-03-2018 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 489 83.62 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 SUPERFAMILY SSF51412 5 92 3.66E-123 T 28-03-2018 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 SUPERFAMILY SSF51412 220 480 3.66E-123 T 28-03-2018 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 PIRSF PIRSF000130 1 491 8.7E-208 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 476 3.8E-161 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 Gene3D G3DSA:3.20.20.70 3 486 4.8E-110 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 Pfam PF00571 CBS domain 155 204 1.0E-7 T 28-03-2018 IPR000644 CBS domain CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 Pfam PF00571 CBS domain 98 144 1.5E-6 T 28-03-2018 IPR000644 CBS domain CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 7.3E-197 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 SMART SM00116 161 209 5.0E-10 T 28-03-2018 IPR000644 CBS domain CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 SMART SM00116 98 148 2.6E-7 T 28-03-2018 IPR000644 CBS domain CPF12_RS05565 a33e698f0ca177e31ec073eb1d55fb30 491 SMART SM01240 9 476 0.0 T 28-03-2018 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 Gene3D G3DSA:3.40.190.10 114 177 1.9E-28 T 28-03-2018 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 185 2.6E-62 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 144 165 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 SUPERFAMILY SSF53850 2 208 5.79E-66 T 28-03-2018 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 Pfam PF01634 ATP phosphoribosyltransferase 54 204 2.0E-50 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 Gene3D G3DSA:3.40.190.10 1 113 4.5E-37 T 28-03-2018 CPF12_RS00110 91b34d4e23ceab2eb06428a7f138c926 216 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 209 57.052 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CPF12_RS10395 667fb61daba793f29d90cb99b874bc22 272 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 262 4.1E-85 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CPF12_RS10395 667fb61daba793f29d90cb99b874bc22 272 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 269 17.991 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CPF12_RS10395 667fb61daba793f29d90cb99b874bc22 272 Pfam PF02673 Bacitracin resistance protein BacA 7 263 1.2E-86 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 Pfam PF01479 S4 domain 356 399 4.6E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 Gene3D G3DSA:1.10.240.10 224 324 6.4E-34 T 28-03-2018 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 6.3E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 6.3E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 6.3E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 6.3E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 SUPERFAMILY SSF55174 321 419 2.22E-21 T 28-03-2018 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 Gene3D G3DSA:3.10.290.10 325 420 3.4E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 419 1.1E-128 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 SUPERFAMILY SSF52374 1 323 3.75E-107 T 28-03-2018 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.0E-80 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 Gene3D G3DSA:3.40.50.620 2 223 4.0E-68 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS08795 6464c194effb02f75b9c26645e26e349 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 419 44.074 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 Gene3D G3DSA:2.30.30.40 45 112 2.9E-35 T 28-03-2018 CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 113 3.0E-52 T 28-03-2018 IPR004624 PhnA protein CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 Pfam PF03831 PhnA domain 46 113 2.8E-32 T 28-03-2018 IPR013988 PhnA protein, C-terminal CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 Pfam PF08274 PhnA Zinc-Ribbon 4 31 5.0E-15 T 28-03-2018 IPR013987 PhnA protein, N-terminal CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 SUPERFAMILY SSF82057 41 112 1.79E-27 T 28-03-2018 CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 Gene3D G3DSA:2.20.25.10 2 40 2.7E-14 T 28-03-2018 CPF12_RS04390 08a047bd587f42563dddba5ea13c542d 113 SUPERFAMILY SSF57783 3 37 6.23E-14 T 28-03-2018 CPF12_RS11890 708e4a20270fda091e9d46faf1441b87 266 SUPERFAMILY SSF56300 1 257 4.67E-88 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS11890 708e4a20270fda091e9d46faf1441b87 266 Pfam PF13277 YmdB-like protein 4 255 1.1E-109 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CPF12_RS11890 708e4a20270fda091e9d46faf1441b87 266 PIRSF PIRSF004789 1 264 4.2E-103 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CPF12_RS11890 708e4a20270fda091e9d46faf1441b87 266 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 263 1.9E-108 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CPF12_RS11890 708e4a20270fda091e9d46faf1441b87 266 Gene3D G3DSA:3.60.21.10 1 265 1.3E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS07995 be629ead5c35cfa51bdb92703c7cd655 285 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 280 6.8E-52 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS07995 be629ead5c35cfa51bdb92703c7cd655 285 ProSitePatterns PS01228 Hypothetical cof family signature 1. 8 19 - T 28-03-2018 CPF12_RS07995 be629ead5c35cfa51bdb92703c7cd655 285 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 252 5.2E-28 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS07995 be629ead5c35cfa51bdb92703c7cd655 285 Gene3D G3DSA:3.40.50.1000 1 274 2.1E-34 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07995 be629ead5c35cfa51bdb92703c7cd655 285 SUPERFAMILY SSF56784 3 284 6.4E-59 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07995 be629ead5c35cfa51bdb92703c7cd655 285 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 280 7.6E-53 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 466 488 9.0E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 252 271 9.0E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 494 517 9.0E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 383 394 9.0E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 576 603 9.0E-24 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 Pfam PF02867 Ribonucleotide reductase, barrel domain 177 705 5.5E-136 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 Pfam PF08343 Ribonucleotide reductase N-terminal 18 98 1.9E-30 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 100 172 6.8E-12 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 SUPERFAMILY SSF51998 176 708 2.01E-172 T 28-03-2018 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 565 587 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 103 708 1.0E-150 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 17 726 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 Gene3D G3DSA:3.20.70.20 81 713 2.3E-151 T 28-03-2018 CPF12_RS10455 7bc391bcfe829cda3fdbd2e1f6ffd4b6 726 SUPERFAMILY SSF48168 27 175 2.88E-45 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS08125 c063ec181b70b4491c472fd48a105f8d 305 Gene3D G3DSA:3.40.50.300 3 305 1.8E-52 T 28-03-2018 CPF12_RS08125 c063ec181b70b4491c472fd48a105f8d 305 PIRSF PIRSF000545 1 305 4.8E-130 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CPF12_RS08125 c063ec181b70b4491c472fd48a105f8d 305 SUPERFAMILY SSF52540 5 304 2.97E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08125 c063ec181b70b4491c472fd48a105f8d 305 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 6 305 6.1E-117 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CPF12_RS08125 c063ec181b70b4491c472fd48a105f8d 305 Hamap MF_00215 Pantothenate kinase [coaA]. 1 305 141.23 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CPF12_RS08125 c063ec181b70b4491c472fd48a105f8d 305 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 84 235 4.1E-11 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 PIRSF PIRSF004983 2 578 3.9E-201 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Gene3D G3DSA:3.40.50.970 2 209 4.1E-56 T 28-03-2018 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 5 572 36.302 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Gene3D G3DSA:3.40.50.1220 211 368 8.5E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Pfam PF16582 Middle domain of thiamine pyrophosphate 214 405 3.2E-22 T 28-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Gene3D G3DSA:3.40.50.970 369 575 1.2E-35 T 28-03-2018 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 SUPERFAMILY SSF52518 14 188 1.22E-37 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 11 447 8.0E-153 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 SUPERFAMILY SSF52518 383 575 1.31E-29 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 432 554 2.8E-8 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 SUPERFAMILY SSF52467 168 366 1.13E-9 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS10225 bd3499fe9e55ca01390e98e475210ea2 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 183 2.1E-42 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 Gene3D G3DSA:3.40.190.10 182 253 1.4E-8 T 28-03-2018 CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 Gene3D G3DSA:3.40.190.10 86 181 3.3E-14 T 28-03-2018 CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 Pfam PF03466 LysR substrate binding domain 89 284 3.2E-31 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.7E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 SUPERFAMILY SSF46785 2 111 9.33E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 Gene3D G3DSA:1.10.10.10 1 85 5.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08615 e6a6a26eb788aae39021e1d8251d121f 296 SUPERFAMILY SSF53850 89 286 1.85E-28 T 28-03-2018 CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 SUPERFAMILY SSF52788 7 156 6.15E-45 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 12 152 2.6E-33 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 SMART SM00226 10 155 7.5E-40 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 87 102 2.3E-14 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 129 144 2.3E-14 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 12 29 2.3E-14 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CPF12_RS08155 dfde15ebcea65ee4b7066867c21e112d 161 Gene3D G3DSA:3.40.50.2300 4 161 7.1E-42 T 28-03-2018 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 SUPERFAMILY SSF52141 7 223 6.98E-90 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 SMART SM00986 52 212 1.5E-35 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 8 223 40.298 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 SMART SM00987 52 212 1.5E-35 T 28-03-2018 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 Gene3D G3DSA:3.40.470.10 1 228 1.0E-101 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 Pfam PF03167 Uracil DNA glycosylase superfamily 56 211 8.1E-25 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS11145 dbbef00c529435776024394a749f9908 228 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 10 214 5.6E-83 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 Pfam PF01467 Cytidylyltransferase-like 17 155 2.4E-5 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 Pfam PF13521 AAA domain 176 330 2.8E-15 T 28-03-2018 CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 SUPERFAMILY SSF52374 12 156 4.79E-16 T 28-03-2018 CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 Gene3D G3DSA:3.40.50.620 7 164 4.7E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 14 50 3.5E-9 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 Gene3D G3DSA:3.40.50.300 173 363 1.7E-5 T 28-03-2018 CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 SUPERFAMILY SSF52540 173 327 5.81E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00540 aa3f9c104184cff6e0cef1b50c797073 375 PIRSF PIRSF004776 1 372 1.0E-78 T 28-03-2018 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 268 347 1.3E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 317 323 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Pfam PF12833 Helix-turn-helix domain 106 176 9.7E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 SUPERFAMILY SSF57884 5 86 3.14E-31 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 SUPERFAMILY SSF53155 186 270 1.1E-9 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 267 346 5.2E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 PIRSF PIRSF000409 1 352 2.5E-140 T 28-03-2018 IPR016221 Bifunctional regulatory protein Ada CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 SUPERFAMILY SSF46767 266 347 1.83E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Gene3D G3DSA:3.40.10.10 1 76 4.5E-23 T 28-03-2018 IPR035451 Ada-like domain CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Pfam PF02805 Metal binding domain of Ada 12 73 7.6E-29 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Gene3D G3DSA:1.10.10.10 264 349 1.3E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Gene3D G3DSA:3.30.160.70 186 263 5.4E-12 T 28-03-2018 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 Gene3D G3DSA:3.90.1240.10 77 185 1.6E-7 T 28-03-2018 CPF12_RS04435 668c2c9ac7615e1651f54eee3f87d413 352 SMART SM00342 98 179 4.3E-4 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS00045 45dfa6406b4e760dc6149e1f73e6dc09 310 SUPERFAMILY SSF46785 4 57 3.23E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00045 45dfa6406b4e760dc6149e1f73e6dc09 310 PIRSF PIRSF016838 1 309 3.1E-16 T 28-03-2018 IPR028349 Protein PafC CPF12_RS00045 45dfa6406b4e760dc6149e1f73e6dc09 310 Pfam PF13280 WYL domain 138 305 2.1E-26 T 28-03-2018 IPR026881 WYL domain CPF12_RS00045 45dfa6406b4e760dc6149e1f73e6dc09 310 Gene3D G3DSA:1.10.10.10 1 71 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00045 45dfa6406b4e760dc6149e1f73e6dc09 310 Pfam PF08279 HTH domain 5 56 1.3E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS08255 3c58e6321bf920872aea224a6f8e42a5 256 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 7 160 1.4E-39 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CPF12_RS08255 3c58e6321bf920872aea224a6f8e42a5 256 SMART SM00943 7 161 5.9E-44 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CPF12_RS08255 3c58e6321bf920872aea224a6f8e42a5 256 Pfam PF08708 Primase C terminal 1 (PriCT-1) 187 245 1.1E-10 T 28-03-2018 IPR014820 Primase, C-terminal 1 CPF12_RS08255 3c58e6321bf920872aea224a6f8e42a5 256 SMART SM00942 183 246 9.7E-12 T 28-03-2018 IPR014820 Primase, C-terminal 1 CPF12_RS08255 3c58e6321bf920872aea224a6f8e42a5 256 SUPERFAMILY SSF56747 2 178 6.34E-40 T 28-03-2018 CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 13 237 8.4E-115 T 28-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 SUPERFAMILY SSF81464 17 115 4.58E-23 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 30 107 2.8E-12 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 PIRSF PIRSF000292 1 305 2.7E-107 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 SUPERFAMILY SSF49503 122 277 3.89E-40 T 28-03-2018 IPR008972 Cupredoxin CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 Gene3D G3DSA:2.60.40.420 113 279 3.5E-38 T 28-03-2018 IPR008972 Cupredoxin CPF12_RS05540 390c30d1c1593397316549d98f13b3b9 336 Gene3D G3DSA:1.10.287.90 27 112 3.2E-24 T 28-03-2018 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 Gene3D G3DSA:1.10.1740.10 15 98 2.8E-18 T 28-03-2018 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 201 7.9E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 SUPERFAMILY SSF88946 7 99 1.06E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 PIRSF PIRSF002939 3 204 1.1E-62 T 28-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 Pfam PF08281 Sigma-70, region 4 158 201 4.8E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 SUPERFAMILY SSF46894 145 203 2.3E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 Pfam PF04542 Sigma-70 region 2 31 100 5.5E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS05975 90174277f4b618a95c914bcc06d96df2 205 Gene3D G3DSA:1.10.10.10 129 203 1.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 Pfam PF00672 HAMP domain 188 235 1.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 SUPERFAMILY SSF47384 231 309 1.96E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 Gene3D G3DSA:3.30.565.10 314 463 4.8E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 SUPERFAMILY SSF55874 311 461 5.34E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 SMART SM00387 353 463 5.1E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 SMART SM00304 188 239 1.2E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 Gene3D G3DSA:1.10.287.130 237 305 2.9E-12 T 28-03-2018 CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 SMART SM00388 247 309 8.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 458 3.6E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 SUPERFAMILY SSF158472 188 235 2.22E-5 T 28-03-2018 CPF12_RS04635 9ae4d4d03dc68132a5eb48abe28940d8 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 308 3.9E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05270 d5b4c043b011c2cb60fa7818b8a73869 451 SUPERFAMILY SSF103473 6 428 7.76E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05270 d5b4c043b011c2cb60fa7818b8a73869 451 Pfam PF13347 MFS/sugar transport protein 11 432 1.4E-76 T 28-03-2018 CPF12_RS05270 d5b4c043b011c2cb60fa7818b8a73869 451 Gene3D G3DSA:1.20.1250.20 4 200 1.1E-8 T 28-03-2018 CPF12_RS05270 d5b4c043b011c2cb60fa7818b8a73869 451 Gene3D G3DSA:1.20.1250.20 218 429 1.3E-7 T 28-03-2018 CPF12_RS05270 d5b4c043b011c2cb60fa7818b8a73869 451 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 444 2.8E-94 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 Gene3D G3DSA:3.40.47.10 175 320 2.1E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 SUPERFAMILY SSF53901 169 386 1.92E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 Gene3D G3DSA:3.40.47.10 7 174 5.0E-10 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 SUPERFAMILY SSF53901 2 166 8.64E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 164 1.3E-18 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 1.5E-158 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 266 352 6.1E-13 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CPF12_RS01545 024d92ab78e66b377a1ac244da5c4ec7 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 177 250 1.3E-7 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CPF12_RS06475 73cb23c03e7420bdbd42665dab844fca 158 Pfam PF00430 ATP synthase B/B' CF(0) 6 135 4.9E-38 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CPF12_RS06475 73cb23c03e7420bdbd42665dab844fca 158 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 9 153 3.0E-39 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CPF12_RS06475 73cb23c03e7420bdbd42665dab844fca 158 Gene3D G3DSA:1.20.5.620 46 120 1.1E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CPF12_RS06475 73cb23c03e7420bdbd42665dab844fca 158 SUPERFAMILY SSF81573 61 119 6.28E-9 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CPF12_RS06475 73cb23c03e7420bdbd42665dab844fca 158 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 136 12.913 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CPF12_RS06100 7d452826b836d89e5f30b5c318ff59cc 63 Pfam PF00831 Ribosomal L29 protein 4 60 5.0E-26 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06100 7d452826b836d89e5f30b5c318ff59cc 63 Gene3D G3DSA:1.10.287.310 1 63 4.0E-26 T 28-03-2018 CPF12_RS06100 7d452826b836d89e5f30b5c318ff59cc 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 7.6E-25 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06100 7d452826b836d89e5f30b5c318ff59cc 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.754 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06100 7d452826b836d89e5f30b5c318ff59cc 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06100 7d452826b836d89e5f30b5c318ff59cc 63 SUPERFAMILY SSF46561 1 62 1.24E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 SUPERFAMILY SSF53187 292 372 3.83E-78 T 28-03-2018 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 SUPERFAMILY SSF53187 4 190 3.83E-78 T 28-03-2018 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 8 359 7.7E-114 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 Pfam PF01546 Peptidase family M20/M25/M40 66 370 2.7E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 PIRSF PIRSF005962 1 376 3.5E-117 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 SUPERFAMILY SSF55031 176 287 3.93E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 Pfam PF07687 Peptidase dimerisation domain 179 273 5.6E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 Gene3D G3DSA:3.40.630.10 241 375 3.0E-16 T 28-03-2018 CPF12_RS06350 2bf5b3781d7ed7abd323ebf711e85dfc 380 Gene3D G3DSA:3.40.630.10 2 213 2.2E-47 T 28-03-2018 CPF12_RS08715 1972f753703da13033b2a03e6f8dcae1 195 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 29.407 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CPF12_RS08715 1972f753703da13033b2a03e6f8dcae1 195 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 187 4.3E-68 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CPF12_RS08715 1972f753703da13033b2a03e6f8dcae1 195 Gene3D G3DSA:3.40.50.170 1 194 2.9E-62 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS08715 1972f753703da13033b2a03e6f8dcae1 195 Pfam PF00551 Formyl transferase 1 180 4.8E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS08715 1972f753703da13033b2a03e6f8dcae1 195 SUPERFAMILY SSF53328 1 187 5.23E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 SUPERFAMILY SSF48179 183 329 8.67E-69 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 PIRSF PIRSF000116 2 204 2.6E-35 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 PIRSF PIRSF000116 202 330 9.6E-14 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 43.719 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 1.3E-74 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 1.3E-131 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 Gene3D G3DSA:1.10.1040.10 78 330 1.4E-115 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 SUPERFAMILY SSF51735 3 182 1.07E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 9.7E-66 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CPF12_RS01935 bfc8d15c346b0b7a5e0f870efec851c7 331 Gene3D G3DSA:3.40.50.720 2 77 1.5E-4 T 28-03-2018 CPF12_RS01245 f32774760b53fa5efe2cb8b2439a25de 158 SUPERFAMILY SSF55068 1 147 4.45E-43 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS01245 f32774760b53fa5efe2cb8b2439a25de 158 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 151 24.702 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS01245 f32774760b53fa5efe2cb8b2439a25de 158 Gene3D G3DSA:3.30.1060.10 1 154 3.1E-37 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS01245 f32774760b53fa5efe2cb8b2439a25de 158 Pfam PF01625 Peptide methionine sulfoxide reductase 3 146 8.9E-40 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 503 717 2.2E-45 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 180 399 5.6E-59 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Pfam PF07549 SecD/SecF GG Motif 472 496 2.1E-5 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Pfam PF07549 SecD/SecF GG Motif 32 50 0.094 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Gene3D G3DSA:1.20.1640.10 196 411 1.3E-33 T 28-03-2018 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Gene3D G3DSA:1.20.1640.10 522 741 5.6E-27 T 28-03-2018 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 SUPERFAMILY SSF82866 216 409 3.66E-40 T 28-03-2018 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 406 4.1E-107 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 448 732 22.207 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 477 720 2.5E-55 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 PRINTS PR01755 Bacterial translocase SecF protein signature 633 651 3.3E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 PRINTS PR01755 Bacterial translocase SecF protein signature 585 599 3.3E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 PRINTS PR01755 Bacterial translocase SecF protein signature 475 490 3.3E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 PRINTS PR01755 Bacterial translocase SecF protein signature 669 684 3.3E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 420 33.69 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 SUPERFAMILY SSF82866 554 729 1.57E-31 T 28-03-2018 CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Pfam PF02355 Protein export membrane protein 243 402 2.4E-13 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CPF12_RS01860 a9f3dcea677916be53bc7f723435e00f 756 Pfam PF02355 Protein export membrane protein 545 727 2.2E-51 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CPF12_RS07835 7d61ce7c3fae8b1a537e0faf1d29f0a2 148 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 141 1.7E-53 T 28-03-2018 CPF12_RS07835 7d61ce7c3fae8b1a537e0faf1d29f0a2 148 Pfam PF01592 NifU-like N terminal domain 10 129 4.0E-29 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CPF12_RS07835 7d61ce7c3fae8b1a537e0faf1d29f0a2 148 Gene3D G3DSA:3.90.1010.10 3 142 1.8E-51 T 28-03-2018 CPF12_RS07835 7d61ce7c3fae8b1a537e0faf1d29f0a2 148 SUPERFAMILY SSF82649 3 141 1.36E-48 T 28-03-2018 CPF12_RS07710 6e8b3f79410aa02a64b1d87e3e95372e 106 Pfam PF02635 DsrE/DsrF-like family 5 105 5.1E-5 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein CPF12_RS07710 6e8b3f79410aa02a64b1d87e3e95372e 106 Gene3D G3DSA:3.40.1260.10 1 105 3.7E-18 T 28-03-2018 CPF12_RS07710 6e8b3f79410aa02a64b1d87e3e95372e 106 SUPERFAMILY SSF75169 2 105 1.65E-15 T 28-03-2018 IPR027396 DsrEFH-like CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 265 24.54 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 SUPERFAMILY SSF51735 3 160 2.39E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 SUPERFAMILY SSF48179 161 264 6.97E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 264 5.8E-37 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 264 1.3E-75 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 PIRSF PIRSF000193 1 265 4.9E-76 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 Gene3D G3DSA:3.40.50.720 1 159 8.7E-24 T 28-03-2018 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 Gene3D G3DSA:1.10.3730.10 160 265 1.0E-39 T 28-03-2018 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CPF12_RS08960 d81c996c91689801ab376984f3fe2196 265 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 86 3.0E-15 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CPF12_RS04485 bc270f61b0ec9c5735763c594b95c6d0 239 SUPERFAMILY SSF161098 17 209 1.22E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04485 bc270f61b0ec9c5735763c594b95c6d0 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 224 2.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04485 bc270f61b0ec9c5735763c594b95c6d0 239 Gene3D G3DSA:1.10.3720.10 2 229 6.4E-38 T 28-03-2018 CPF12_RS04485 bc270f61b0ec9c5735763c594b95c6d0 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 118 4.2E-21 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CPF12_RS00320 96ea535a5bb00d9dab6c6226c8f7a278 429 SUPERFAMILY SSF48208 6 427 1.59E-174 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CPF12_RS00320 96ea535a5bb00d9dab6c6226c8f7a278 429 Pfam PF06824 Metal-independent alpha-mannosidase (GH125) 26 420 4.4E-147 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CPF12_RS00320 96ea535a5bb00d9dab6c6226c8f7a278 429 PIRSF PIRSF028846 1 429 1.4E-208 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CPF12_RS00320 96ea535a5bb00d9dab6c6226c8f7a278 429 Gene3D G3DSA:1.50.10.10 7 428 4.8E-158 T 28-03-2018 CPF12_RS00320 96ea535a5bb00d9dab6c6226c8f7a278 429 SMART SM01149 25 421 8.4E-264 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CPF12_RS03280 19a978c0f98c571cd18250fd96d3373d 178 Gene3D G3DSA:2.40.128.110 1 178 3.2E-56 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CPF12_RS03280 19a978c0f98c571cd18250fd96d3373d 178 SMART SM00867 5 175 4.7E-69 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CPF12_RS03280 19a978c0f98c571cd18250fd96d3373d 178 SUPERFAMILY SSF101874 5 174 2.88E-55 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CPF12_RS03280 19a978c0f98c571cd18250fd96d3373d 178 Pfam PF04264 YceI-like domain 6 173 4.5E-46 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 7.7E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 7.7E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 7.7E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 7.7E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 296 322 7.7E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 Gene3D G3DSA:3.30.420.40 4 155 5.6E-39 T 28-03-2018 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 Pfam PF06723 MreB/Mbl protein 6 331 1.4E-146 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 SUPERFAMILY SSF53067 7 143 3.45E-41 T 28-03-2018 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 Gene3D G3DSA:3.90.640.10 192 249 3.7E-30 T 28-03-2018 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 SUPERFAMILY SSF53067 145 328 3.87E-48 T 28-03-2018 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 Gene3D G3DSA:3.30.420.40 250 313 1.6E-9 T 28-03-2018 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 Gene3D G3DSA:3.30.420.40 156 191 4.0E-4 T 28-03-2018 CPF12_RS01105 87f7ff95ba96ab1d58dffcdcc78ecf8a 338 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 332 6.0E-153 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 SUPERFAMILY SSF46785 3 84 2.66E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 SUPERFAMILY SSF53850 89 235 1.99E-9 T 28-03-2018 CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 Gene3D G3DSA:1.10.10.10 1 86 3.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05220 6a3e604e0e4976bfe990dc0275937f20 276 Gene3D G3DSA:3.40.190.10 91 215 0.0011 T 28-03-2018 CPF12_RS05630 c40911a90fe826ee4701bd603266b68b 206 SMART SM00530 6 61 1.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05630 c40911a90fe826ee4701bd603266b68b 206 Gene3D G3DSA:3.30.1190.10 27 136 5.0E-17 T 28-03-2018 CPF12_RS05630 c40911a90fe826ee4701bd603266b68b 206 Gene3D G3DSA:1.10.10.60 2 26 2.5E-5 T 28-03-2018 CPF12_RS05630 c40911a90fe826ee4701bd603266b68b 206 Pfam PF01381 Helix-turn-helix 7 61 2.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05630 c40911a90fe826ee4701bd603266b68b 206 SUPERFAMILY SSF47413 1 66 1.8E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 Gene3D G3DSA:3.30.540.10 1 155 2.5E-30 T 28-03-2018 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 Gene3D G3DSA:3.40.190.80 156 262 3.4E-20 T 28-03-2018 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 Pfam PF00459 Inositol monophosphatase family 4 252 2.3E-44 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 2.6E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 2.6E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 2.6E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.6E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 2.6E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CPF12_RS02140 b617f91044d1b9b3cac4768dabb14cbf 264 SUPERFAMILY SSF56655 2 254 2.09E-55 T 28-03-2018 CPF12_RS11045 43ee1800ab215a1f5f7dcfd2efc7a76b 240 SUPERFAMILY SSF117856 7 239 1.31E-78 T 28-03-2018 CPF12_RS11045 43ee1800ab215a1f5f7dcfd2efc7a76b 240 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 7 239 2.7E-91 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CPF12_RS11045 43ee1800ab215a1f5f7dcfd2efc7a76b 240 Pfam PF03306 Alpha-acetolactate decarboxylase 9 227 7.8E-81 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CPF12_RS11045 43ee1800ab215a1f5f7dcfd2efc7a76b 240 Gene3D G3DSA:3.30.1330.80 97 204 1.3E-42 T 28-03-2018 CPF12_RS11045 43ee1800ab215a1f5f7dcfd2efc7a76b 240 Gene3D G3DSA:3.30.1330.80 6 96 1.7E-32 T 28-03-2018 CPF12_RS11045 43ee1800ab215a1f5f7dcfd2efc7a76b 240 PIRSF PIRSF001332 1 240 5.7E-92 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CPF12_RS12330 93ddc58dcbaacbd1706a924cca95a577 185 Pfam PF01765 Ribosome recycling factor 20 183 1.2E-62 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CPF12_RS12330 93ddc58dcbaacbd1706a924cca95a577 185 Gene3D G3DSA:1.10.132.20 75 184 5.3E-37 T 28-03-2018 CPF12_RS12330 93ddc58dcbaacbd1706a924cca95a577 185 Gene3D G3DSA:1.10.132.20 2 74 6.1E-9 T 28-03-2018 CPF12_RS12330 93ddc58dcbaacbd1706a924cca95a577 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 15 185 9.3E-72 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CPF12_RS12330 93ddc58dcbaacbd1706a924cca95a577 185 SUPERFAMILY SSF55194 1 185 6.41E-68 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CPF12_RS12330 93ddc58dcbaacbd1706a924cca95a577 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.828 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 Pfam PF01195 Peptidyl-tRNA hydrolase 3 184 1.6E-61 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 184 3.2E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 177 37.262 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 SUPERFAMILY SSF53178 1 184 2.09E-68 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 Gene3D G3DSA:3.40.50.1470 1 188 1.2E-72 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CPF12_RS05775 bf2066c81630bc90b1babf4e18312979 188 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CPF12_RS02295 1d24bff5c5eefc8d43dd4d5f3d324392 388 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 327 351 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CPF12_RS02295 1d24bff5c5eefc8d43dd4d5f3d324392 388 Pfam PF01098 Cell cycle protein 16 369 4.3E-82 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CPF12_RS03575 93beb229fed64e6a88b34b274d70cdc3 218 Pfam PF03006 Haemolysin-III related 15 210 3.0E-42 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CPF12_RS03575 93beb229fed64e6a88b34b274d70cdc3 218 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 18 218 5.0E-65 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 Gene3D G3DSA:3.20.20.70 1 232 9.2E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 SMART SM00934 3 227 2.3E-86 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 1 232 39.022 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 SUPERFAMILY SSF51366 2 231 1.08E-64 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 227 2.7E-58 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 226 5.8E-44 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11350 963e95c04d38c1ec8bb442458b843c56 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 55 68 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 ProSitePatterns PS00761 Signal peptidases I signature 3. 120 133 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 6.9E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 115 134 6.9E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 71 83 6.9E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 155 2.5E-46 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 SUPERFAMILY SSF51306 22 155 1.52E-41 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 Gene3D G3DSA:2.10.109.10 20 156 3.0E-36 T 28-03-2018 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 ProSitePatterns PS00760 Signal peptidases I lysine active site. 73 85 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 Pfam PF00717 Peptidase S24-like 31 95 1.6E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS09830 d352cfe510c00a6001b5aadcc6088507 156 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CPF12_RS12215 1b58a5dffa580e264d670919444a1227 58 Pfam PF10031 Small integral membrane protein (DUF2273) 5 50 2.3E-14 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 Gene3D G3DSA:1.20.1250.20 252 467 5.3E-23 T 28-03-2018 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 425 3.2E-90 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 Pfam PF07690 Major Facilitator Superfamily 18 409 5.0E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 Gene3D G3DSA:1.20.1250.20 6 192 1.3E-27 T 28-03-2018 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 SUPERFAMILY SSF103473 12 203 4.32E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 SUPERFAMILY SSF103473 249 466 4.32E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 6.6E-5 T 28-03-2018 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 6.6E-5 T 28-03-2018 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 6.6E-5 T 28-03-2018 CPF12_RS08540 25c6dabf82e52f56c89209b7a7b7a17b 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 6.6E-5 T 28-03-2018 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 Gene3D G3DSA:1.10.10.10 129 232 4.1E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 SUPERFAMILY SSF46894 129 229 2.08E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 Pfam PF00072 Response regulator receiver domain 4 114 6.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 SMART SM00448 1 113 2.1E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 228 7.3E-31 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 Gene3D G3DSA:3.40.50.2300 1 128 3.8E-32 T 28-03-2018 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 SMART SM00862 153 228 3.0E-31 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS09670 7e2f1d4c868c7ee0b99e1a82a5947298 232 SUPERFAMILY SSF52172 1 122 5.27E-34 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 SUPERFAMILY SSF52016 637 893 5.89E-83 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 Gene3D G3DSA:3.30.499.10 28 237 2.2E-73 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 Pfam PF00330 Aconitase family (aconitate hydratase) 73 567 2.5E-172 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 893 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 SUPERFAMILY SSF53732 3 632 7.72E-219 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 ProSitePatterns PS01244 Aconitase family signature 2. 498 511 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 168 176 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 498 511 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 201 214 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 215 230 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 291 304 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 370 384 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 277 290 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 144 157 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 PRINTS PR00415 Aconitase family signature 436 447 2.7E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 ProSitePatterns PS00450 Aconitase family signature 1. 432 448 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 Gene3D G3DSA:3.40.1060.10 238 369 1.0E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 Gene3D G3DSA:3.30.499.10 370 581 1.1E-60 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 Gene3D G3DSA:3.20.19.10 658 896 1.2E-83 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CPF12_RS12350 5b18f60ce682b6f505ee2c1705912448 899 Pfam PF00694 Aconitase C-terminal domain 697 823 1.3E-41 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS00805 5d2cfe9a955585c14229b7ccc9fa4825 192 Gene3D G3DSA:1.10.260.40 1 166 2.8E-24 T 28-03-2018 CPF12_RS00805 5d2cfe9a955585c14229b7ccc9fa4825 192 SUPERFAMILY SSF47413 1 65 3.22E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS00805 5d2cfe9a955585c14229b7ccc9fa4825 192 Pfam PF01381 Helix-turn-helix 7 61 4.5E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS00805 5d2cfe9a955585c14229b7ccc9fa4825 192 SMART SM00530 6 61 3.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS11310 8927e7b9a540de397ffa18b94ff2a277 184 SUPERFAMILY SSF53271 7 172 3.54E-42 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS11310 8927e7b9a540de397ffa18b94ff2a277 184 Pfam PF00156 Phosphoribosyl transferase domain 6 163 4.6E-25 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CPF12_RS11310 8927e7b9a540de397ffa18b94ff2a277 184 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 180 37.042 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CPF12_RS11310 8927e7b9a540de397ffa18b94ff2a277 184 Gene3D G3DSA:3.40.50.2020 2 184 6.4E-35 T 28-03-2018 CPF12_RS08825 8a65fc03e233a2b726995effa956f0c8 421 Gene3D G3DSA:3.30.565.10 277 409 1.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08825 8a65fc03e233a2b726995effa956f0c8 421 Gene3D G3DSA:1.10.287.130 207 276 4.4E-5 T 28-03-2018 CPF12_RS08825 8a65fc03e233a2b726995effa956f0c8 421 Pfam PF14501 GHKL domain 318 411 4.0E-11 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CPF12_RS08825 8a65fc03e233a2b726995effa956f0c8 421 SUPERFAMILY SSF55874 289 398 2.8E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08135 1001f00fbc5f65c68c93fd404ac73e0a 657 PIRSF PIRSF005091 2 629 6.9E-186 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CPF12_RS08135 1001f00fbc5f65c68c93fd404ac73e0a 657 SUPERFAMILY SSF53649 249 643 1.42E-71 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS08135 1001f00fbc5f65c68c93fd404ac73e0a 657 Pfam PF00884 Sulfatase 251 542 8.1E-35 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CPF12_RS08135 1001f00fbc5f65c68c93fd404ac73e0a 657 Gene3D G3DSA:3.40.720.10 243 552 3.0E-38 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 Gene3D G3DSA:3.40.50.300 1 241 8.4E-24 T 28-03-2018 CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 Gene3D G3DSA:3.40.50.300 242 532 6.9E-19 T 28-03-2018 CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 551 9.3E-170 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 507 2.6E-17 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 SUPERFAMILY SSF52540 4 50 5.32E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 SUPERFAMILY SSF52540 290 506 5.32E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 SUPERFAMILY SSF52540 1 220 1.67E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09250 2b2ca860b44b02f0ad0d5d06a20c3b35 560 PIRSF PIRSF003128 1 556 2.5E-173 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 SUPERFAMILY SSF51445 5 43 1.77E-152 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 SUPERFAMILY SSF51445 71 483 1.77E-152 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 Pfam PF00232 Glycosyl hydrolase family 1 4 483 1.7E-128 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 Gene3D G3DSA:3.20.20.80 4 489 8.2E-143 T 28-03-2018 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 448 460 1.2E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 382 390 1.2E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 423 440 1.2E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 402 413 1.2E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS10360 037938e1fdf091c2e5f082c6976b8a80 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 317 331 1.2E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS02985 56c3b0cc40939797c6610e228b2c8f41 404 Gene3D G3DSA:3.50.50.60 2 148 2.6E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02985 56c3b0cc40939797c6610e228b2c8f41 404 SUPERFAMILY SSF51905 3 173 9.5E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02985 56c3b0cc40939797c6610e228b2c8f41 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 1.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02985 56c3b0cc40939797c6610e228b2c8f41 404 Gene3D G3DSA:3.50.50.60 152 351 1.1E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02985 56c3b0cc40939797c6610e228b2c8f41 404 SUPERFAMILY SSF51905 178 335 8.1E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02985 56c3b0cc40939797c6610e228b2c8f41 404 SUPERFAMILY SSF51905 4 87 8.1E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1178 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 SMART SM00968 518 637 5.6E-37 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 PIRSF PIRSF005719 1 1186 0.0 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 SUPERFAMILY SSF75553 484 686 1.96E-50 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Gene3D G3DSA:3.40.50.300 812 1183 3.7E-28 T 28-03-2018 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1171 2.4E-72 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 23.058 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Gene3D G3DSA:1.20.1170.10 363 780 1.1E-16 T 28-03-2018 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Pfam PF06470 SMC proteins Flexible Hinge Domain 518 637 3.8E-25 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Gene3D G3DSA:1.20.120.330 223 362 0.019 T 28-03-2018 CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 SUPERFAMILY SSF52540 979 1180 7.63E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 SUPERFAMILY SSF52540 1 207 7.63E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11545 81067150807fb94c7e07f1fa6c0960a0 1187 Gene3D G3DSA:3.40.50.300 1 222 1.6E-42 T 28-03-2018 CPF12_RS01100 69b15adc3791f97e05f636c2602a9fe6 283 Gene3D G3DSA:1.20.5.1000 66 128 5.7E-4 T 28-03-2018 CPF12_RS01100 69b15adc3791f97e05f636c2602a9fe6 283 PIRSF PIRSF038471 1 283 6.9E-64 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CPF12_RS01100 69b15adc3791f97e05f636c2602a9fe6 283 Pfam PF04085 rod shape-determining protein MreC 123 275 6.9E-44 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CPF12_RS01100 69b15adc3791f97e05f636c2602a9fe6 283 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 2 280 3.2E-51 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CPF12_RS05960 9a6a0ce6ab0653bba036995d2fdae4a7 135 SUPERFAMILY SSF69065 3 124 5.93E-41 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS05960 9a6a0ce6ab0653bba036995d2fdae4a7 135 Pfam PF00636 Ribonuclease III domain 11 109 2.0E-16 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS05960 9a6a0ce6ab0653bba036995d2fdae4a7 135 SMART SM00535 1 132 5.3E-4 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS05960 9a6a0ce6ab0653bba036995d2fdae4a7 135 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 127 27.937 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CPF12_RS05960 9a6a0ce6ab0653bba036995d2fdae4a7 135 Gene3D G3DSA:1.10.1520.10 2 132 2.8E-19 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS05960 9a6a0ce6ab0653bba036995d2fdae4a7 135 PIRSF PIRSF005520 1 132 1.1E-50 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CPF12_RS01065 5d29b5a99867fcca3943b12add929746 113 SUPERFAMILY SSF118010 6 109 2.88E-25 T 28-03-2018 IPR007422 Cysteine protease Prp CPF12_RS01065 5d29b5a99867fcca3943b12add929746 113 Pfam PF04327 Cysteine protease Prp 2 107 2.0E-21 T 28-03-2018 IPR007422 Cysteine protease Prp CPF12_RS01065 5d29b5a99867fcca3943b12add929746 113 Gene3D G3DSA:3.30.70.1490 2 111 1.9E-26 T 28-03-2018 IPR007422 Cysteine protease Prp CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 Pfam PF13580 SIS domain 35 160 2.2E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 Gene3D G3DSA:1.10.8.10 242 267 1.4E-8 T 28-03-2018 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 Gene3D G3DSA:1.10.8.10 268 295 2.9E-4 T 28-03-2018 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 294 42.35 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 5 294 3.5E-121 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 184 201 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 Gene3D G3DSA:3.40.50.10490 9 241 1.3E-55 T 28-03-2018 CPF12_RS06245 8dbba01869522f748a116770f84ee702 297 SUPERFAMILY SSF53697 4 248 1.05E-72 T 28-03-2018 CPF12_RS03825 43c5d01d2473fb771f60897d9b22ac68 484 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 13 60 1.4E-10 T 28-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain CPF12_RS03825 43c5d01d2473fb771f60897d9b22ac68 484 Gene3D G3DSA:1.10.10.10 89 150 0.028 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03825 43c5d01d2473fb771f60897d9b22ac68 484 Gene3D G3DSA:1.10.10.10 4 76 2.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06050 d2c254a890c76f279ec2a9f9921fa194 268 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 43 267 2.0E-42 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CPF12_RS06050 d2c254a890c76f279ec2a9f9921fa194 268 SUPERFAMILY SSF53474 115 252 5.15E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS06050 d2c254a890c76f279ec2a9f9921fa194 268 SUPERFAMILY SSF53474 53 86 5.15E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS06050 d2c254a890c76f279ec2a9f9921fa194 268 Gene3D G3DSA:3.40.50.1820 49 268 5.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 Pfam PF00005 ABC transporter 366 515 1.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 Pfam PF00664 ABC transporter transmembrane region 34 303 1.8E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 Gene3D G3DSA:3.40.50.300 335 591 1.6E-70 T 28-03-2018 CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 SUPERFAMILY SSF90123 12 329 3.66E-79 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 Gene3D G3DSA:1.20.1560.10 2 334 4.7E-70 T 28-03-2018 CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 SUPERFAMILY SSF52540 341 585 7.56E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS12410 df489ad7cebd34cb9c2b9e27aeec2d21 593 SMART SM00382 375 567 1.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07395 b4e51b4b51140fe233418920df2f1a0d 394 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 4 388 1.8E-158 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CPF12_RS07395 b4e51b4b51140fe233418920df2f1a0d 394 PIRSF PIRSF016636 3 387 5.3E-85 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CPF12_RS07395 b4e51b4b51140fe233418920df2f1a0d 394 PIRSF PIRSF500216 1 393 2.8E-162 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CPF12_RS07395 b4e51b4b51140fe233418920df2f1a0d 394 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 116 371 7.4E-21 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 Gene3D G3DSA:1.20.5.1150 16 52 8.4E-19 T 28-03-2018 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 Pfam PF01165 Ribosomal protein S21 5 57 2.5E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 2.0E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 8.0E-8 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.832 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.8E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.8E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.8E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS09310 8c56afdf3f8b209e8eb8282d61890ff7 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.8E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 41 364 2.1E-116 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Gene3D G3DSA:2.30.42.10 96 175 7.5E-20 T 28-03-2018 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 SMART SM00228 88 159 1.9E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Gene3D G3DSA:1.10.101.10 364 441 3.2E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 SUPERFAMILY SSF47090 364 433 7.95E-15 T 28-03-2018 IPR002477 Peptidoglycan binding-like CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 SUPERFAMILY SSF52096 28 106 1.42E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 SUPERFAMILY SSF52096 180 357 1.42E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 SMART SM00245 161 353 7.4E-67 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Gene3D G3DSA:3.90.226.10 176 363 2.3E-62 T 28-03-2018 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Pfam PF13180 PDZ domain 89 167 2.3E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 SUPERFAMILY SSF50156 82 171 3.68E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Gene3D G3DSA:3.30.750.44 19 95 4.0E-18 T 28-03-2018 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Pfam PF03572 Peptidase family S41 186 352 5.2E-53 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CPF12_RS10705 f9eb142ec13008f561dc1aff35ddee39 458 Pfam PF01471 Putative peptidoglycan binding domain 376 429 2.3E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 4.4E-81 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 494 6.1E-220 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 SUPERFAMILY SSF53067 4 255 7.5E-95 T 28-03-2018 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 PIRSF PIRSF000538 3 496 1.7E-177 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 Gene3D G3DSA:3.30.420.40 1 249 2.0E-85 T 28-03-2018 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 SUPERFAMILY SSF53067 254 493 2.59E-84 T 28-03-2018 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 Gene3D G3DSA:3.30.420.40 250 495 6.9E-78 T 28-03-2018 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 58.517 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CPF12_RS04880 a5a0ab20b4683eb23a31325f1432a5b0 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 450 7.2E-63 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CPF12_RS02880 f57966c05a6e665405bf681865164fee 909 Pfam PF13514 AAA domain 1 206 5.7E-25 T 28-03-2018 CPF12_RS02880 f57966c05a6e665405bf681865164fee 909 Gene3D G3DSA:3.40.50.300 646 903 1.1E-8 T 28-03-2018 CPF12_RS02880 f57966c05a6e665405bf681865164fee 909 Gene3D G3DSA:3.40.50.300 1 336 8.9E-13 T 28-03-2018 CPF12_RS02880 f57966c05a6e665405bf681865164fee 909 SUPERFAMILY SSF52540 702 891 3.64E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02880 f57966c05a6e665405bf681865164fee 909 SUPERFAMILY SSF52540 1 51 3.64E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PIRSF PIRSF001369 1 372 7.2E-149 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PRINTS PR00143 Citrate synthase signature 305 321 1.6E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PRINTS PR00143 Citrate synthase signature 124 137 1.6E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PRINTS PR00143 Citrate synthase signature 195 223 1.6E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PRINTS PR00143 Citrate synthase signature 325 339 1.6E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PRINTS PR00143 Citrate synthase signature 173 188 1.6E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 PRINTS PR00143 Citrate synthase signature 248 268 1.6E-41 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 372 4.6E-156 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 Gene3D G3DSA:1.10.580.10 301 352 2.3E-10 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 SUPERFAMILY SSF48256 5 372 1.44E-128 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 Gene3D G3DSA:1.10.580.10 12 261 3.6E-82 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CPF12_RS08465 1004e2443c41121f554fe7478b0529a0 372 Pfam PF00285 Citrate synthase, C-terminal domain 7 355 1.7E-126 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CPF12_RS05985 2ecb2c37c5c4f953023904e3a52f3435 61 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 7 59 1.4E-20 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CPF12_RS05985 2ecb2c37c5c4f953023904e3a52f3435 61 Gene3D G3DSA:1.20.5.1030 5 55 1.1E-19 T 28-03-2018 CPF12_RS05985 2ecb2c37c5c4f953023904e3a52f3435 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 2 58 11.49 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS05985 2ecb2c37c5c4f953023904e3a52f3435 61 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 58 2.6E-19 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS05985 2ecb2c37c5c4f953023904e3a52f3435 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 7 35 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 Gene3D G3DSA:3.20.20.120 128 431 4.3E-109 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 SMART SM01193 4 134 2.8E-97 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PIRSF PIRSF001400 1 428 1.6E-198 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 SMART SM01192 139 428 2.1E-225 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 SUPERFAMILY SSF54826 3 139 4.57E-59 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 426 1.0E-138 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 SUPERFAMILY SSF51604 139 428 2.69E-132 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 Hamap MF_00318 Enolase [eno]. 2 414 45.968 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 Gene3D G3DSA:3.30.390.10 3 126 6.1E-55 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 Pfam PF03952 Enolase, N-terminal domain 4 134 2.5E-61 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PRINTS PR00148 Enolase signature 37 51 1.6E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PRINTS PR00148 Enolase signature 337 351 1.6E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PRINTS PR00148 Enolase signature 107 123 1.6E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PRINTS PR00148 Enolase signature 314 325 1.6E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PRINTS PR00148 Enolase signature 161 174 1.6E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 PRINTS PR00148 Enolase signature 366 383 1.6E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06920 bcda3e476a661c8f9e3ebeaf9d77c403 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 2.5E-216 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS09730 1116f3da039ca7c09182e489abd833b5 172 Pfam PF00702 haloacid dehalogenase-like hydrolase 19 128 2.7E-11 T 28-03-2018 CPF12_RS09730 1116f3da039ca7c09182e489abd833b5 172 Gene3D G3DSA:3.40.50.1000 15 39 0.15 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09730 1116f3da039ca7c09182e489abd833b5 172 SUPERFAMILY SSF56784 17 149 1.03E-23 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09730 1116f3da039ca7c09182e489abd833b5 172 Gene3D G3DSA:3.40.50.1000 40 163 1.9E-20 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS09730 1116f3da039ca7c09182e489abd833b5 172 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 2 164 2.9E-47 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CPF12_RS09730 1116f3da039ca7c09182e489abd833b5 172 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 27 137 1.6E-20 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CPF12_RS12170 ca54f105dfd46c544358ae556cb6abe1 309 Gene3D G3DSA:3.30.2350.10 1 224 2.6E-81 T 28-03-2018 CPF12_RS12170 ca54f105dfd46c544358ae556cb6abe1 309 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 302 18.517 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS12170 ca54f105dfd46c544358ae556cb6abe1 309 SUPERFAMILY SSF55120 1 220 2.52E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS12170 ca54f105dfd46c544358ae556cb6abe1 309 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 7.6E-81 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS12170 ca54f105dfd46c544358ae556cb6abe1 309 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 178 237 1.0E-11 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CPF12_RS12170 ca54f105dfd46c544358ae556cb6abe1 309 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 177 6.6E-57 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 Gene3D G3DSA:1.10.10.10 1 64 4.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 Pfam PF08220 DeoR-like helix-turn-helix domain 5 58 4.9E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 SMART SM01134 71 232 8.4E-57 T 28-03-2018 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 2.7E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 2.7E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 Pfam PF00455 DeoR C terminal sensor domain 73 230 3.9E-46 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 SUPERFAMILY SSF46785 2 61 6.62E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 SMART SM00420 5 57 6.6E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 Gene3D G3DSA:3.40.50.1360 71 237 7.9E-34 T 28-03-2018 CPF12_RS00700 dd77332e9b0e016dc3cfc7599d27f5d4 252 SUPERFAMILY SSF100950 73 232 3.66E-31 T 28-03-2018 CPF12_RS10585 931b89c797a781893b7190aaf5cc1014 245 Pfam PF00589 Phage integrase family 59 225 3.1E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS10585 931b89c797a781893b7190aaf5cc1014 245 Gene3D G3DSA:1.10.443.10 39 229 4.7E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS10585 931b89c797a781893b7190aaf5cc1014 245 SUPERFAMILY SSF56349 2 226 1.5E-45 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 24 266 1.9E-77 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 Gene3D G3DSA:3.40.50.1820 18 268 1.7E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 6.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 SUPERFAMILY SSF53474 12 266 1.06E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 13 267 32.463 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CPF12_RS10230 37e1b4d7c89126f38d113c5a6c45d693 268 Pfam PF00561 alpha/beta hydrolase fold 24 142 9.2E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Pfam PF01225 Mur ligase family, catalytic domain 23 97 1.0E-4 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Gene3D G3DSA:3.90.190.20 313 453 2.6E-34 T 28-03-2018 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Gene3D G3DSA:3.40.1190.10 93 309 6.5E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 SUPERFAMILY SSF53244 314 451 1.34E-30 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 394 1.3E-10 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 SUPERFAMILY SSF63418 4 99 2.35E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 452 32.119 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 451 1.2E-121 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 SUPERFAMILY SSF53623 102 309 1.7E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Gene3D G3DSA:3.40.1390.10 1 92 5.5E-22 T 28-03-2018 CPF12_RS09005 3f7466bbecaf778dec2a1135555d496a 453 Pfam PF08245 Mur ligase middle domain 108 292 6.6E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 SUPERFAMILY SSF47413 1 58 3.2E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 Pfam PF13377 Periplasmic binding protein-like domain 169 326 1.2E-19 T 28-03-2018 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 SUPERFAMILY SSF53822 60 330 6.64E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.0E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 Gene3D G3DSA:1.10.260.40 2 53 1.5E-14 T 28-03-2018 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 SMART SM00354 1 70 1.6E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 Gene3D G3DSA:3.40.50.2300 54 173 9.6E-24 T 28-03-2018 CPF12_RS07640 b35fa8710a69612b2bf0db934773d4ab 335 Gene3D G3DSA:3.40.50.2300 174 309 1.2E-31 T 28-03-2018 CPF12_RS04020 5dcd3c7d85b622572d5815ed783d92a9 151 Hamap MF_01071 UPF0266 membrane protein YobD [yobD]. 1 151 22.685 T 28-03-2018 IPR009328 Protein of unknown function DUF986 CPF12_RS04020 5dcd3c7d85b622572d5815ed783d92a9 151 Pfam PF06173 Protein of unknown function (DUF986) 6 149 5.2E-40 T 28-03-2018 IPR009328 Protein of unknown function DUF986 CPF12_RS04020 5dcd3c7d85b622572d5815ed783d92a9 151 ProDom PD091196 MEMBRANE UPF0266 TRANSMEMBRANE INNER YOBD PLU2700 LMO0779 PM0830 YPO1755/Y2554/YP1637 LIN0773 22 144 4.0E-18 T 28-03-2018 IPR009328 Protein of unknown function DUF986 CPF12_RS02110 f9caf339cc0072d9aa6e9ed3577d5f9b 305 Hamap MF_01664 Heme A synthase [ctaA]. 1 302 25.03 T 28-03-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 CPF12_RS02110 f9caf339cc0072d9aa6e9ed3577d5f9b 305 Pfam PF02628 Cytochrome oxidase assembly protein 7 287 1.8E-37 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CPF12_RS08555 3bf2f11f9ea16ec2038d6e8d904c3a33 150 SUPERFAMILY SSF54593 3 145 6.62E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS08555 3bf2f11f9ea16ec2038d6e8d904c3a33 150 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 138 2.1E-9 T 28-03-2018 IPR028973 PhnB-like CPF12_RS08555 3bf2f11f9ea16ec2038d6e8d904c3a33 150 Gene3D G3DSA:3.10.180.10 1 150 1.3E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS07290 75fbd57f67159e67b8ebccb991958425 192 SUPERFAMILY SSF53254 1 178 1.61E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS07290 75fbd57f67159e67b8ebccb991958425 192 Gene3D G3DSA:3.40.50.1240 1 190 9.3E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS07290 75fbd57f67159e67b8ebccb991958425 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 181 6.2E-39 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS07290 75fbd57f67159e67b8ebccb991958425 192 PIRSF PIRSF000709 2 97 3.3E-10 T 28-03-2018 CPF12_RS07290 75fbd57f67159e67b8ebccb991958425 192 SMART SM00855 3 147 1.0E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS07290 75fbd57f67159e67b8ebccb991958425 192 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CPF12_RS07610 c1999a90821b8f6af517aedb2b38ab65 107 SUPERFAMILY SSF89360 1 105 2.16E-15 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS07610 c1999a90821b8f6af517aedb2b38ab65 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 105 6.0E-13 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS07610 c1999a90821b8f6af517aedb2b38ab65 107 Gene3D G3DSA:2.60.300.12 1 107 1.4E-17 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 Pfam PF00561 alpha/beta hydrolase fold 22 246 6.7E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 Gene3D G3DSA:3.40.50.1820 2 259 3.2E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 SUPERFAMILY SSF53474 5 260 2.78E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 PRINTS PR00412 Epoxide hydrolase signature 235 257 2.3E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 PRINTS PR00412 Epoxide hydrolase signature 101 114 2.3E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 PRINTS PR00412 Epoxide hydrolase signature 46 61 2.3E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 4.4E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 4.4E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS12040 0720f6f2b0dea71eaf57245a6d114766 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 4.4E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 5 419 1.5E-124 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 Gene3D G3DSA:3.65.10.10 221 425 6.8E-58 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 Gene3D G3DSA:3.65.10.10 19 220 1.0E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 425 32.654 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 424 1.5E-128 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 SUPERFAMILY SSF55205 3 423 3.92E-134 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CPF12_RS09540 0b983117c9660ff60e7440c15501b04e 425 PIRSF PIRSF000505 1 425 2.6E-120 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CPF12_RS01870 f4adfa7d329e93037bfa3a5708d998bc 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 7 374 6.5E-174 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CPF12_RS01870 f4adfa7d329e93037bfa3a5708d998bc 380 SUPERFAMILY SSF51713 5 370 6.15E-159 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CPF12_RS01870 f4adfa7d329e93037bfa3a5708d998bc 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 133 366 6.9E-88 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CPF12_RS01870 f4adfa7d329e93037bfa3a5708d998bc 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 5 369 56.957 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CPF12_RS01870 f4adfa7d329e93037bfa3a5708d998bc 380 Gene3D G3DSA:3.20.20.105 1 375 2.9E-157 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CPF12_RS01870 f4adfa7d329e93037bfa3a5708d998bc 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 373 2.9E-167 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CPF12_RS06975 742b2fb9aada1c7750b854e6a5c6c685 115 Gene3D G3DSA:3.40.30.30 3 102 4.7E-38 T 28-03-2018 CPF12_RS06975 742b2fb9aada1c7750b854e6a5c6c685 115 Pfam PF07315 Protein of unknown function (DUF1462) 9 100 1.1E-37 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 CPF12_RS06975 742b2fb9aada1c7750b854e6a5c6c685 115 PIRSF PIRSF010603 1 106 2.8E-43 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 CPF12_RS06975 742b2fb9aada1c7750b854e6a5c6c685 115 SUPERFAMILY SSF52833 2 105 5.14E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 SUPERFAMILY SSF100950 3 148 5.48E-38 T 28-03-2018 CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 SUPERFAMILY SSF75445 128 205 3.53E-23 T 28-03-2018 CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 220 4.5E-74 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 219 3.1E-55 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 223 29.486 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 Gene3D G3DSA:3.40.50.1360 1 139 6.2E-38 T 28-03-2018 CPF12_RS02580 b4248ce99bcec8e985c1158054cd7209 226 Gene3D G3DSA:3.30.70.260 140 203 1.2E-24 T 28-03-2018 CPF12_RS08595 a9e2b164c06625bd4bfb6334e56e038a 384 Gene3D G3DSA:3.40.640.10 42 266 3.0E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS08595 a9e2b164c06625bd4bfb6334e56e038a 384 Pfam PF00155 Aminotransferase class I and II 29 375 8.7E-61 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS08595 a9e2b164c06625bd4bfb6334e56e038a 384 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 228 241 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CPF12_RS08595 a9e2b164c06625bd4bfb6334e56e038a 384 SUPERFAMILY SSF53383 5 382 5.98E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS08595 a9e2b164c06625bd4bfb6334e56e038a 384 Gene3D G3DSA:3.90.1150.10 267 384 1.3E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 269 1.6E-102 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 269 2.4E-106 T 28-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 PIRSF PIRSF000477 1 271 3.7E-109 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 SUPERFAMILY SSF53167 1 271 1.24E-93 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 Gene3D G3DSA:3.40.50.1580 1 271 4.0E-66 T 28-03-2018 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 74 115 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CPF12_RS09390 99a537e07842388e74ba34b51a851b75 271 Pfam PF01048 Phosphorylase superfamily 22 268 3.8E-52 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Hamap MF_00974 DNA primase [dnaG]. 4 595 28.39 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 TIGRFAM TIGR01391 dnaG: DNA primase 4 426 7.6E-148 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Gene3D G3DSA:3.90.580.10 1 103 1.0E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Pfam PF13155 Toprim-like 272 357 8.0E-17 T 28-03-2018 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Gene3D G3DSA:3.90.980.10 116 249 1.1E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Pfam PF08275 DNA primase catalytic core, N-terminal domain 139 260 7.5E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 SMART SM00493 268 339 4.6E-15 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Pfam PF10410 DnaB-helicase binding domain of primase 379 431 3.3E-7 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 PIRSF PIRSF002811 2 603 1.2E-185 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 SMART SM00400 36 90 7.0E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Pfam PF01807 CHC2 zinc finger 6 97 1.2E-38 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Gene3D G3DSA:1.10.860.10 465 556 1.1E-5 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 SUPERFAMILY SSF56731 123 431 1.96E-99 T 28-03-2018 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 SUPERFAMILY SSF57783 4 99 7.14E-36 T 28-03-2018 CPF12_RS11100 4940d498e6d6fadaad2359d4825cf996 605 Gene3D G3DSA:3.40.1360.10 250 375 5.3E-34 T 28-03-2018 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.4E-40 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.434 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 Pfam PF00281 Ribosomal protein L5 24 80 6.6E-28 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 Gene3D G3DSA:3.30.1440.10 1 179 5.3E-78 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 PIRSF PIRSF002161 1 179 2.4E-64 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06120 e9cf1075b990474bff1621433d23db26 179 SUPERFAMILY SSF55282 3 178 1.55E-75 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS09805 56e410571b431f70fcd9331ff16106d3 84 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 84 15.848 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS09805 56e410571b431f70fcd9331ff16106d3 84 Gene3D G3DSA:1.20.58.110 1 84 3.1E-24 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS09805 56e410571b431f70fcd9331ff16106d3 84 SUPERFAMILY SSF46992 3 83 3.27E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS09805 56e410571b431f70fcd9331ff16106d3 84 Pfam PF01649 Ribosomal protein S20 2 82 3.4E-25 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS09805 56e410571b431f70fcd9331ff16106d3 84 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 17 84 1.0E-12 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS09805 56e410571b431f70fcd9331ff16106d3 84 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 4.2E-21 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 Pfam PF00005 ABC transporter 21 163 3.3E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 SUPERFAMILY SSF52540 5 245 3.19E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 Pfam PF08402 TOBE domain 275 343 1.9E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 Gene3D G3DSA:3.40.50.300 1 244 1.1E-74 T 28-03-2018 CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 SMART SM00382 30 213 1.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS08095 b1f1c47586f6f307a308b2bba874c93e 362 SUPERFAMILY SSF50331 238 343 5.53E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 156 168 1.5E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 127 138 1.5E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 116 126 1.5E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 Gene3D G3DSA:1.10.10.10 2 68 8.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 Pfam PF00717 Peptidase S24-like 119 187 1.5E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 TIGRFAM TIGR00498 lexA: repressor LexA 3 200 7.1E-77 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 Gene3D G3DSA:2.10.109.10 84 201 5.4E-26 T 28-03-2018 CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 Pfam PF01726 LexA DNA binding domain 3 65 1.1E-27 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 SUPERFAMILY SSF51306 78 199 5.23E-36 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 SUPERFAMILY SSF46785 2 70 4.05E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12445 8538e407cc938e76e02d435e5bd5efb5 201 Hamap MF_00015 LexA repressor [lexA]. 3 201 34.545 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CPF12_RS04955 86664726a7fb651a91531017869fb903 128 Pfam PF01467 Cytidylyltransferase-like 5 120 3.9E-22 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS04955 86664726a7fb651a91531017869fb903 128 SUPERFAMILY SSF52374 1 124 1.05E-33 T 28-03-2018 CPF12_RS04955 86664726a7fb651a91531017869fb903 128 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 6.5E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS04955 86664726a7fb651a91531017869fb903 128 Gene3D G3DSA:3.40.50.620 1 127 9.5E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS04955 86664726a7fb651a91531017869fb903 128 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 1.2E-59 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 CPF12_RS01035 86e7884a51b31fac52dca61919e99d53 307 Pfam PF04960 Glutaminase 19 307 4.6E-98 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CPF12_RS01035 86e7884a51b31fac52dca61919e99d53 307 Hamap MF_00313 Glutaminase [glsA]. 1 307 39.061 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CPF12_RS01035 86e7884a51b31fac52dca61919e99d53 307 SUPERFAMILY SSF56601 5 307 1.12E-88 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS01035 86e7884a51b31fac52dca61919e99d53 307 TIGRFAM TIGR03814 Gln_ase: glutaminase A 7 307 1.3E-99 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CPF12_RS01035 86e7884a51b31fac52dca61919e99d53 307 Gene3D G3DSA:3.40.710.10 2 307 2.5E-108 T 28-03-2018 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 Pfam PF01037 Lrp/AsnC ligand binding domain 73 131 6.3E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 5.2E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 Gene3D G3DSA:3.30.70.920 51 137 2.5E-13 T 28-03-2018 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 SUPERFAMILY SSF54909 63 134 1.47E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 SUPERFAMILY SSF46785 1 60 1.72E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.4E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.4E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.4E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 SMART SM00344 1 105 3.4E-28 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CPF12_RS11270 b2d3b54ffe4554f486af7664e3441c99 138 Gene3D G3DSA:1.10.10.10 1 50 7.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 Gene3D G3DSA:3.90.76.10 51 212 4.0E-35 T 28-03-2018 CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 475 7.8E-72 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 PIRSF PIRSF002741 1 557 1.6E-88 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 Gene3D G3DSA:3.40.190.10 213 308 1.5E-20 T 28-03-2018 CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 91 113 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 Gene3D G3DSA:3.10.105.10 309 528 1.6E-43 T 28-03-2018 CPF12_RS03700 175107a494789f13227a0e97bfd4db33 557 SUPERFAMILY SSF53850 40 556 3.57E-109 T 28-03-2018 CPF12_RS08880 9704201699f1a04487fdca583a0b659e 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 156 5.1E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS08880 9704201699f1a04487fdca583a0b659e 178 Gene3D G3DSA:2.160.10.10 30 178 3.8E-33 T 28-03-2018 CPF12_RS08880 9704201699f1a04487fdca583a0b659e 178 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 130 158 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CPF12_RS08880 9704201699f1a04487fdca583a0b659e 178 SUPERFAMILY SSF51161 13 175 2.22E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS00025 126bc7a23d93ebfc6d11711eb7ce4f8b 290 SMART SM00530 7 68 0.0046 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS00025 126bc7a23d93ebfc6d11711eb7ce4f8b 290 SUPERFAMILY SSF47413 2 74 2.91E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS00025 126bc7a23d93ebfc6d11711eb7ce4f8b 290 Pfam PF13464 Domain of unknown function (DUF4115) 212 281 4.5E-12 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 CPF12_RS00025 126bc7a23d93ebfc6d11711eb7ce4f8b 290 Gene3D G3DSA:1.10.260.40 1 83 3.6E-12 T 28-03-2018 CPF12_RS00025 126bc7a23d93ebfc6d11711eb7ce4f8b 290 Pfam PF13413 Helix-turn-helix domain 8 68 2.4E-22 T 28-03-2018 CPF12_RS00230 2c1a48edf9192c3ffc3bc739e3eaad0c 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 369 1.9E-107 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CPF12_RS00230 2c1a48edf9192c3ffc3bc739e3eaad0c 377 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 155 183 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CPF12_RS00230 2c1a48edf9192c3ffc3bc739e3eaad0c 377 SUPERFAMILY SSF56796 5 375 8.11E-108 T 28-03-2018 CPF12_RS00230 2c1a48edf9192c3ffc3bc739e3eaad0c 377 Gene3D G3DSA:1.20.1090.10 167 377 5.9E-61 T 28-03-2018 CPF12_RS00230 2c1a48edf9192c3ffc3bc739e3eaad0c 377 Gene3D G3DSA:3.40.50.1970 1 166 2.8E-40 T 28-03-2018 CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 4.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 4.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 Gene3D G3DSA:1.20.120.530 95 226 5.1E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 SUPERFAMILY SSF48008 99 223 2.38E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 SMART SM00895 100 220 4.5E-20 T 28-03-2018 IPR011711 GntR, C-terminal CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 SMART SM00345 16 75 5.2E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 Gene3D G3DSA:1.10.10.10 1 77 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 4.8E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 Pfam PF07729 FCD domain 100 219 8.1E-20 T 28-03-2018 IPR011711 GntR, C-terminal CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 SUPERFAMILY SSF46785 8 79 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07910 c00712f84e29f89b961c2812e2b022c0 228 SUPERFAMILY SSF46785 108 119 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02395 9f729a1959eaf14918fd4676252d23b1 359 PIRSF PIRSF003314 6 348 1.9E-120 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CPF12_RS02395 9f729a1959eaf14918fd4676252d23b1 359 Gene3D G3DSA:3.20.20.70 9 350 9.3E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS02395 9f729a1959eaf14918fd4676252d23b1 359 Pfam PF01070 FMN-dependent dehydrogenase 163 329 8.0E-15 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CPF12_RS02395 9f729a1959eaf14918fd4676252d23b1 359 SUPERFAMILY SSF51395 30 349 5.23E-73 T 28-03-2018 CPF12_RS02395 9f729a1959eaf14918fd4676252d23b1 359 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 9 338 35.979 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CPF12_RS02395 9f729a1959eaf14918fd4676252d23b1 359 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 11 337 6.8E-119 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 161 1.9E-53 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 Gene3D G3DSA:1.10.1040.10 183 333 1.6E-54 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 325 37.131 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 Gene3D G3DSA:3.40.50.720 4 182 2.3E-40 T 28-03-2018 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 SUPERFAMILY SSF51735 5 181 4.0E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 1.2E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 1.2E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 1.2E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 1.2E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 1.2E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 1.2E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 323 3.2E-53 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 SUPERFAMILY SSF48179 182 334 1.39E-56 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS09480 6d7498d9c9090d53d8c9a97c9ea1f51d 335 PIRSF PIRSF000114 2 335 5.7E-113 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CPF12_RS08565 46c7e6c27c21012ff8cc541b0d1e7084 230 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS08565 46c7e6c27c21012ff8cc541b0d1e7084 230 Pfam PF00005 ABC transporter 24 170 5.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS08565 46c7e6c27c21012ff8cc541b0d1e7084 230 Gene3D G3DSA:3.40.50.300 1 227 6.7E-61 T 28-03-2018 CPF12_RS08565 46c7e6c27c21012ff8cc541b0d1e7084 230 SUPERFAMILY SSF52540 6 223 1.59E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08565 46c7e6c27c21012ff8cc541b0d1e7084 230 SMART SM00382 33 218 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04350 cf0a5e86d854c90a0b3dd349b8dd7d0f 481 Gene3D G3DSA:3.30.1360.60 4 80 9.5E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04350 cf0a5e86d854c90a0b3dd349b8dd7d0f 481 SUPERFAMILY SSF55604 6 81 2.48E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04350 cf0a5e86d854c90a0b3dd349b8dd7d0f 481 Pfam PF02378 Phosphotransferase system, EIIC 106 408 9.7E-32 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04350 cf0a5e86d854c90a0b3dd349b8dd7d0f 481 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04350 cf0a5e86d854c90a0b3dd349b8dd7d0f 481 Pfam PF00367 phosphotransferase system, EIIB 10 41 2.1E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS05745 bd67d0d09daa0e1247cb1c5732974fcf 104 SUPERFAMILY SSF160537 1 83 7.85E-32 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CPF12_RS05745 bd67d0d09daa0e1247cb1c5732974fcf 104 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 26.565 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CPF12_RS05745 bd67d0d09daa0e1247cb1c5732974fcf 104 Gene3D G3DSA:3.30.1120.40 1 83 6.4E-36 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CPF12_RS05745 bd67d0d09daa0e1247cb1c5732974fcf 104 Pfam PF04026 SpoVG 1 81 2.0E-35 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 SMART SM00862 137 210 3.3E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 210 2.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 SUPERFAMILY SSF52172 1 161 6.15E-39 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 Gene3D G3DSA:1.10.10.10 118 212 6.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 SMART SM00448 1 111 1.6E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 Pfam PF00072 Response regulator receiver domain 3 111 2.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS04640 e2897a029bf306381c7c10d7b346b4a9 212 Gene3D G3DSA:3.40.50.2300 1 117 9.8E-36 T 28-03-2018 CPF12_RS04440 8f90f7d715541e34ea3410c913702084 267 Pfam PF13714 Phosphoenolpyruvate phosphomutase 29 259 4.5E-64 T 28-03-2018 CPF12_RS04440 8f90f7d715541e34ea3410c913702084 267 Gene3D G3DSA:3.20.20.60 19 266 1.6E-47 T 28-03-2018 CPF12_RS04440 8f90f7d715541e34ea3410c913702084 267 SUPERFAMILY SSF51621 19 263 4.4E-50 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CPF12_RS10675 0a48c60a35e17014170f20acd96d6385 215 Gene3D G3DSA:3.40.50.300 1 213 8.0E-38 T 28-03-2018 CPF12_RS10675 0a48c60a35e17014170f20acd96d6385 215 Pfam PF00005 ABC transporter 18 144 1.6E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10675 0a48c60a35e17014170f20acd96d6385 215 SMART SM00382 26 200 4.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10675 0a48c60a35e17014170f20acd96d6385 215 SUPERFAMILY SSF52540 2 196 7.2E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10675 0a48c60a35e17014170f20acd96d6385 215 ProSitePatterns PS00211 ABC transporters family signature. 117 131 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS01730 fb1842f09c66ccb8fc5f9efc3b4de5be 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.497 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01730 fb1842f09c66ccb8fc5f9efc3b4de5be 49 SUPERFAMILY SSF57829 1 49 3.15E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CPF12_RS01730 fb1842f09c66ccb8fc5f9efc3b4de5be 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 7.6E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01730 fb1842f09c66ccb8fc5f9efc3b4de5be 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS01730 fb1842f09c66ccb8fc5f9efc3b4de5be 49 Pfam PF00471 Ribosomal protein L33 3 49 7.6E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11520 140c314264f244f8a13486212373607b 336 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 332 2.8E-124 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CPF12_RS11520 140c314264f244f8a13486212373607b 336 Pfam PF02504 Fatty acid synthesis protein 1 318 5.5E-116 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CPF12_RS11520 140c314264f244f8a13486212373607b 336 Gene3D G3DSA:3.40.718.10 1 330 5.0E-106 T 28-03-2018 CPF12_RS11520 140c314264f244f8a13486212373607b 336 PIRSF PIRSF002465 1 333 1.5E-124 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CPF12_RS11520 140c314264f244f8a13486212373607b 336 SUPERFAMILY SSF53659 1 325 3.21E-103 T 28-03-2018 CPF12_RS11520 140c314264f244f8a13486212373607b 336 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 333 144.234 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CPF12_RS00655 52f13adc5d34f2aa6c7491cf2af03c9c 423 Pfam PF02687 FtsX-like permease family 319 416 2.2E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS00655 52f13adc5d34f2aa6c7491cf2af03c9c 423 Pfam PF12704 MacB-like periplasmic core domain 21 256 1.9E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 Gene3D G3DSA:3.60.40.10 71 320 5.7E-22 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 SMART SM00331 105 319 5.9E-49 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 Gene3D G3DSA:1.10.1240.30 1 69 3.6E-17 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 1 68 3.8E-16 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 SUPERFAMILY SSF81606 118 318 3.14E-6 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 SUPERFAMILY SSF101215 2 70 9.15E-17 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 4 79 8.0E-11 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CPF12_RS09045 a77756c637f7e0a0b5f74fa9538e178b 321 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 132 319 2.9E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 Gene3D G3DSA:3.40.1450.10 77 296 1.5E-99 T 28-03-2018 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 SUPERFAMILY SSF53649 309 507 5.63E-74 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 SUPERFAMILY SSF53649 4 77 5.63E-74 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 507 3.5E-207 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 508 49.383 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 297 1.6E-86 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 SUPERFAMILY SSF64158 77 308 1.2E-88 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 PIRSF PIRSF001492 1 509 5.6E-205 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 Gene3D G3DSA:3.40.720.10 297 502 1.4E-55 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CPF12_RS06915 a0b46a30cdd3543f9d6222238d487fad 509 Pfam PF01676 Metalloenzyme superfamily 5 496 4.5E-76 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 PIRSF PIRSF001413 1 399 2.6E-168 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 Gene3D G3DSA:3.40.50.1100 12 69 1.7E-6 T 28-03-2018 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 Gene3D G3DSA:3.40.50.1100 70 200 9.0E-40 T 28-03-2018 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 394 52.854 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 381 5.1E-46 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 10 392 2.2E-195 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 SUPERFAMILY SSF53686 6 391 4.85E-148 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CPF12_RS01005 cea1ba70d94555e898573cd3d7b9e49f 399 Gene3D G3DSA:3.40.50.1100 201 399 3.3E-37 T 28-03-2018 CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 Pfam PF04397 LytTr DNA-binding domain 143 240 1.1E-11 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 SUPERFAMILY SSF52172 1 119 5.27E-19 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 SMART SM00448 4 115 9.4E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 Gene3D G3DSA:3.40.50.2300 1 128 1.3E-17 T 28-03-2018 CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 Gene3D G3DSA:2.40.50.40 131 202 3.7E-8 T 28-03-2018 CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 SMART SM00850 141 241 7.5E-5 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS11660 30385ac6af68eec816bad92a26247e7f 247 Pfam PF00072 Response regulator receiver domain 7 114 8.4E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS04495 7b67da0c029f4b5ec05f640733fa56ad 251 SMART SM00382 26 216 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04495 7b67da0c029f4b5ec05f640733fa56ad 251 SUPERFAMILY SSF52540 1 238 2.89E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04495 7b67da0c029f4b5ec05f640733fa56ad 251 Pfam PF00005 ABC transporter 17 168 1.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04495 7b67da0c029f4b5ec05f640733fa56ad 251 Gene3D G3DSA:3.40.50.300 1 246 4.2E-76 T 28-03-2018 CPF12_RS04495 7b67da0c029f4b5ec05f640733fa56ad 251 PIRSF PIRSF039085 1 244 2.1E-107 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CPF12_RS04495 7b67da0c029f4b5ec05f640733fa56ad 251 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS12145 c9eb4cae83c2e84e759a4c77018a263a 146 Gene3D G3DSA:1.20.1290.10 1 145 1.4E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CPF12_RS12145 c9eb4cae83c2e84e759a4c77018a263a 146 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 78 1.3E-22 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CPF12_RS12145 c9eb4cae83c2e84e759a4c77018a263a 146 SUPERFAMILY SSF69118 3 144 1.44E-43 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CPF12_RS12145 c9eb4cae83c2e84e759a4c77018a263a 146 Pfam PF02627 Carboxymuconolactone decarboxylase family 15 94 2.2E-22 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CPF12_RS01250 7ee29d586ee31d3f76f2077bd319579f 279 SUPERFAMILY SSF53955 1 145 9.21E-50 T 28-03-2018 IPR023346 Lysozyme-like domain CPF12_RS01250 7ee29d586ee31d3f76f2077bd319579f 279 Pfam PF00959 Phage lysozyme 30 136 8.7E-25 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 CPF12_RS01250 7ee29d586ee31d3f76f2077bd319579f 279 Gene3D G3DSA:1.10.530.40 1 141 1.3E-51 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 CPF12_RS01250 7ee29d586ee31d3f76f2077bd319579f 279 Gene3D G3DSA:2.40.50.110 213 275 7.6E-6 T 28-03-2018 CPF12_RS01250 7ee29d586ee31d3f76f2077bd319579f 279 Gene3D G3DSA:2.40.50.110 142 209 0.0013 T 28-03-2018 CPF12_RS01250 7ee29d586ee31d3f76f2077bd319579f 279 SUPERFAMILY SSF50044 243 273 7.61E-6 T 28-03-2018 IPR001452 SH3 domain GO:0005515 CPF12_RS07535 0603fd6f79ccf81feea8c0171b5b2d20 305 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07535 0603fd6f79ccf81feea8c0171b5b2d20 305 Gene3D G3DSA:3.40.50.300 3 252 1.8E-60 T 28-03-2018 CPF12_RS07535 0603fd6f79ccf81feea8c0171b5b2d20 305 Pfam PF00005 ABC transporter 22 164 7.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07535 0603fd6f79ccf81feea8c0171b5b2d20 305 SUPERFAMILY SSF52540 4 230 1.98E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07535 0603fd6f79ccf81feea8c0171b5b2d20 305 SMART SM00382 31 257 1.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 Pfam PF03462 PCRF domain 9 202 6.8E-72 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 39.795 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 SUPERFAMILY SSF75620 8 351 4.58E-131 T 28-03-2018 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 Gene3D G3DSA:1.20.58.410 2 94 4.4E-16 T 28-03-2018 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 Pfam PF00472 RF-1 domain 210 319 4.2E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 SMART SM00937 63 177 1.5E-61 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 354 3.1E-164 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CPF12_RS06435 fe94fde414f641dd6742abd1b4fb3d40 356 Gene3D G3DSA:3.30.160.20 207 295 1.4E-29 T 28-03-2018 CPF12_RS03790 d02ce8723454be044d93fb9d3e369e63 454 SUPERFAMILY SSF141523 332 454 1.7E-34 T 28-03-2018 CPF12_RS03790 d02ce8723454be044d93fb9d3e369e63 454 SUPERFAMILY SSF143985 208 325 1.7E-23 T 28-03-2018 CPF12_RS03790 d02ce8723454be044d93fb9d3e369e63 454 Pfam PF03734 L,D-transpeptidase catalytic domain 334 453 1.7E-22 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CPF12_RS03790 d02ce8723454be044d93fb9d3e369e63 454 Pfam PF12229 Putative peptidoglycan binding domain 98 187 2.9E-8 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CPF12_RS03790 d02ce8723454be044d93fb9d3e369e63 454 Pfam PF12229 Putative peptidoglycan binding domain 200 314 1.9E-13 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CPF12_RS03790 d02ce8723454be044d93fb9d3e369e63 454 Gene3D G3DSA:2.40.440.10 326 454 3.8E-31 T 28-03-2018 CPF12_RS01075 3733552e7cd5c420e03c946a5c509c40 126 Pfam PF01042 Endoribonuclease L-PSP 8 123 2.7E-41 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CPF12_RS01075 3733552e7cd5c420e03c946a5c509c40 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 4.7E-48 T 28-03-2018 IPR006056 RidA family CPF12_RS01075 3733552e7cd5c420e03c946a5c509c40 126 Gene3D G3DSA:3.30.1330.40 1 126 1.6E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS01075 3733552e7cd5c420e03c946a5c509c40 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 120 - T 28-03-2018 IPR019897 RidA, conserved site CPF12_RS01075 3733552e7cd5c420e03c946a5c509c40 126 SUPERFAMILY SSF55298 2 125 3.77E-44 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS06255 42bbeb395c99c26b6e5e5a866027131a 385 SUPERFAMILY SSF50891 276 382 3.6E-23 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS06255 42bbeb395c99c26b6e5e5a866027131a 385 Gene3D G3DSA:3.20.20.70 38 265 1.5E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS06255 42bbeb395c99c26b6e5e5a866027131a 385 Gene3D G3DSA:2.40.100.10 267 383 6.4E-29 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS06255 42bbeb395c99c26b6e5e5a866027131a 385 Pfam PF05913 Bacterial protein of unknown function (DUF871) 38 380 3.2E-99 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CPF12_RS06255 42bbeb395c99c26b6e5e5a866027131a 385 SUPERFAMILY SSF51445 38 267 4.0E-59 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 522 534 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 459 583 2.3E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 Pfam PF00367 phosphotransferase system, EIIB 8 41 3.1E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 SUPERFAMILY SSF51261 452 602 5.93E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 Gene3D G3DSA:3.30.1360.60 2 75 2.4E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 460 580 7.3E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 Pfam PF02378 Phosphotransferase system, EIIC 104 379 1.5E-26 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 604 7.3E-209 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 SUPERFAMILY SSF55604 6 79 3.79E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS10355 49227e35dca60b1571819d6e43a3268e 608 Gene3D G3DSA:2.70.70.10 446 606 4.4E-53 T 28-03-2018 CPF12_RS01535 022a637c2ef402999b4311a52f772c94 388 Pfam PF00155 Aminotransferase class I and II 31 381 1.4E-63 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS01535 022a637c2ef402999b4311a52f772c94 388 SUPERFAMILY SSF53383 1 384 2.23E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS01535 022a637c2ef402999b4311a52f772c94 388 Gene3D G3DSA:3.90.1150.10 2 252 9.3E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS01535 022a637c2ef402999b4311a52f772c94 388 Gene3D G3DSA:3.90.1150.10 253 386 1.1E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS09765 9cdbd0febddf6a2bb4c6df478d3c6832 244 Pfam PF13649 Methyltransferase domain 39 132 5.0E-14 T 28-03-2018 CPF12_RS09765 9cdbd0febddf6a2bb4c6df478d3c6832 244 Gene3D G3DSA:2.20.25.110 140 203 7.1E-21 T 28-03-2018 CPF12_RS09765 9cdbd0febddf6a2bb4c6df478d3c6832 244 Gene3D G3DSA:3.40.50.150 2 137 6.8E-17 T 28-03-2018 CPF12_RS09765 9cdbd0febddf6a2bb4c6df478d3c6832 244 SUPERFAMILY SSF53335 4 244 7.55E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 101 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 Gene3D G3DSA:1.10.10.10 5 141 4.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 Pfam PF12802 MarR family 37 91 6.9E-14 T 28-03-2018 CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 SMART SM00347 28 128 3.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 3.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.4E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS04615 120e826bb07c4003ca2466004e72094c 151 SUPERFAMILY SSF46785 13 143 4.29E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 Gene3D G3DSA:1.10.10.10 1 50 9.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.3E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 Pfam PF01037 Lrp/AsnC ligand binding domain 73 117 2.6E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 SUPERFAMILY SSF46785 1 60 4.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.8E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.8E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.8E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 SUPERFAMILY SSF54909 66 134 3.49E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 SMART SM00344 1 105 1.6E-32 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CPF12_RS03125 2aa355dff6c1e9da0e00cc104d521610 148 Gene3D G3DSA:3.30.70.920 51 134 6.4E-15 T 28-03-2018 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 SUPERFAMILY SSF48208 270 746 2.81E-139 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 Gene3D G3DSA:1.50.10.10 317 681 8.9E-117 T 28-03-2018 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 SUPERFAMILY SSF74650 5 268 2.01E-84 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 15 266 3.5E-56 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 PIRSF PIRSF036289 1 757 1.1E-269 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 Gene3D G3DSA:2.70.98.40 2 269 1.9E-68 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 323 696 7.2E-150 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 700 748 5.6E-14 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CPF12_RS00915 791fcb9bef7b087dfb86e559c1da89a0 757 Gene3D G3DSA:2.60.420.10 682 753 4.0E-21 T 28-03-2018 CPF12_RS10315 2de7abb765724033ef5fd3111da7df29 394 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.0E-23 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CPF12_RS10315 2de7abb765724033ef5fd3111da7df29 394 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 193 393 6.6E-60 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CPF12_RS10315 2de7abb765724033ef5fd3111da7df29 394 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 393 8.6E-136 T 28-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Gene3D G3DSA:3.40.50.300 605 807 2.7E-30 T 28-03-2018 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SMART SM00982 1026 1126 4.1E-37 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Pfam PF03461 TRCF domain 1027 1116 1.5E-26 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SUPERFAMILY SSF52540 379 490 2.66E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SMART SM00490 846 930 1.4E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SMART SM00487 620 810 5.1E-34 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Gene3D G3DSA:3.40.50.300 237 473 0.022 T 28-03-2018 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1100 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SUPERFAMILY SSF143517 1015 1169 1.57E-34 T 28-03-2018 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Gene3D G3DSA:3.40.50.300 10 172 2.6E-5 T 28-03-2018 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Pfam PF00270 DEAD/DEAH box helicase 645 784 7.5E-15 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SUPERFAMILY SSF52540 14 370 1.13E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1130 29.261 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SUPERFAMILY SSF52540 802 1007 3.26E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Pfam PF00271 Helicase conserved C-terminal domain 827 929 1.3E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Gene3D G3DSA:3.40.50.300 809 976 2.7E-23 T 28-03-2018 CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 Pfam PF02559 CarD-like/TRCF domain 500 595 2.0E-30 T 28-03-2018 IPR003711 CarD-like/TRCF domain CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SUPERFAMILY SSF141259 490 568 1.28E-26 T 28-03-2018 IPR003711 CarD-like/TRCF domain CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SUPERFAMILY SSF52540 543 803 8.55E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05780 67e1d869904620662d914cd6fcbf2d02 1177 SMART SM01058 499 596 4.9E-48 T 28-03-2018 IPR003711 CarD-like/TRCF domain CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 249 1.0E-64 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 249 9.0E-63 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 SUPERFAMILY SSF56784 3 254 9.86E-71 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 ProSitePatterns PS01229 Hypothetical cof family signature 2. 204 226 - T 28-03-2018 CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 Gene3D G3DSA:3.40.50.1000 1 255 2.1E-48 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS01415 e829624cf6f0ed0508255230a247536f 256 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 223 7.8E-29 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 9.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 9.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 9.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 SUPERFAMILY SSF51735 3 224 1.26E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 Pfam PF00106 short chain dehydrogenase 3 188 3.4E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 Gene3D G3DSA:3.40.50.720 1 234 2.1E-51 T 28-03-2018 CPF12_RS00400 56c460238d5dbdd9df70de10105af2d1 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CPF12_RS00500 1571980ad1a9cf895e5773d2482468f5 174 SUPERFAMILY SSF46785 3 168 1.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00500 1571980ad1a9cf895e5773d2482468f5 174 Gene3D G3DSA:1.10.10.10 1 93 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00500 1571980ad1a9cf895e5773d2482468f5 174 Pfam PF03551 Transcriptional regulator PadR-like family 6 82 4.6E-12 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 Gene3D G3DSA:3.40.47.10 5 245 3.9E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 SUPERFAMILY SSF53901 3 237 9.04E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 Gene3D G3DSA:3.40.47.10 248 396 3.6E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 SUPERFAMILY SSF53901 202 395 1.11E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 SMART SM00825 Beta-ketoacyl synthase 5 396 7.3E-11 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 232 1.7E-24 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CPF12_RS00675 c0b02a5eef7c221d4121371f07612665 396 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 241 352 1.2E-29 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 PIRSF PIRSF001359 1 288 3.7E-112 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 287 1.1E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 288 6.8E-94 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 Gene3D G3DSA:3.20.20.70 1 288 1.6E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 288 4.1E-116 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CPF12_RS07695 fe5471e34207cdb0af6d811140d4a4f1 288 SUPERFAMILY SSF51569 1 288 4.03E-96 T 28-03-2018 CPF12_RS01915 7b88b11fe5a97fccfd40d0e5b123772a 194 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 194 39.864 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CPF12_RS01915 7b88b11fe5a97fccfd40d0e5b123772a 194 Gene3D G3DSA:3.20.19.10 1 171 4.6E-45 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CPF12_RS01915 7b88b11fe5a97fccfd40d0e5b123772a 194 SUPERFAMILY SSF52016 1 188 9.03E-56 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CPF12_RS01915 7b88b11fe5a97fccfd40d0e5b123772a 194 Pfam PF00694 Aconitase C-terminal domain 1 122 6.7E-34 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CPF12_RS01915 7b88b11fe5a97fccfd40d0e5b123772a 194 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 183 5.6E-71 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CPF12_RS00960 adddb3ff3fa4d222fa75de390241a212 354 Gene3D G3DSA:3.40.50.2300 159 354 1.1E-40 T 28-03-2018 CPF12_RS00960 adddb3ff3fa4d222fa75de390241a212 354 SUPERFAMILY SSF53822 41 305 5.49E-12 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS00960 adddb3ff3fa4d222fa75de390241a212 354 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 40 352 1.1E-74 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CPF12_RS00960 adddb3ff3fa4d222fa75de390241a212 354 Gene3D G3DSA:3.40.50.2300 37 158 3.2E-38 T 28-03-2018 CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 Gene3D G3DSA:3.40.50.300 198 446 4.3E-49 T 28-03-2018 CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 343 1.7E-95 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 Pfam PF00270 DEAD/DEAH box helicase 19 176 3.1E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 SMART SM00490 240 322 2.6E-27 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 Pfam PF00271 Helicase conserved C-terminal domain 214 321 4.8E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 SUPERFAMILY SSF52540 54 339 5.13E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 Pfam PF16124 RecQ zinc-binding 398 442 2.0E-6 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 Gene3D G3DSA:3.40.50.300 1 196 1.0E-31 T 28-03-2018 CPF12_RS09455 e3d6c00002c35ea84d39e5f41eba64f4 476 SMART SM00487 11 206 6.0E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS03640 cbe735d3ce12e25260280b08d449df17 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 250 1.3E-49 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03640 cbe735d3ce12e25260280b08d449df17 257 SUPERFAMILY SSF56784 3 255 1.96E-55 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03640 cbe735d3ce12e25260280b08d449df17 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 224 1.3E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS03640 cbe735d3ce12e25260280b08d449df17 257 Gene3D G3DSA:3.40.50.1000 1 256 3.9E-37 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS03640 cbe735d3ce12e25260280b08d449df17 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 28-03-2018 CPF12_RS03640 cbe735d3ce12e25260280b08d449df17 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 250 9.4E-50 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS09840 7ab4f897910c61fcd3d064e6c3ebbab9 332 Gene3D G3DSA:3.40.710.10 2 332 1.6E-56 T 28-03-2018 CPF12_RS09840 7ab4f897910c61fcd3d064e6c3ebbab9 332 SUPERFAMILY SSF56601 2 321 2.82E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS09840 7ab4f897910c61fcd3d064e6c3ebbab9 332 Pfam PF00144 Beta-lactamase 5 314 4.0E-44 T 28-03-2018 IPR001466 Beta-lactamase-related CPF12_RS02215 3429627770cfce46138ebbc3dd19d038 212 Pfam PF05857 TraX protein 7 203 1.7E-43 T 28-03-2018 IPR008875 TraX CPF12_RS01280 fcfc61553118ff1d74edbc5346fe17f7 565 Pfam PF10651 Domain of unknown function (DUF2479) 8 148 1.3E-29 T 28-03-2018 IPR018913 Domain of unknown function DUF2479 CPF12_RS01280 fcfc61553118ff1d74edbc5346fe17f7 565 Gene3D G3DSA:1.20.120.20 97 240 1.6E-5 T 28-03-2018 CPF12_RS00350 da7b3e0f6dbc02bcbe0a8f4ce65a05d1 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.6E-23 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CPF12_RS00350 da7b3e0f6dbc02bcbe0a8f4ce65a05d1 104 SUPERFAMILY SSF103481 5 102 1.14E-16 T 28-03-2018 CPF12_RS12035 db5c36d6b00f1fb23b71963ddf1068f7 81 Pfam PF00550 Phosphopantetheine attachment site 1 61 3.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS12035 db5c36d6b00f1fb23b71963ddf1068f7 81 SUPERFAMILY SSF47336 1 61 1.44E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS12035 db5c36d6b00f1fb23b71963ddf1068f7 81 ProSitePatterns PS00012 Phosphopantetheine attachment site. 22 37 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CPF12_RS12035 db5c36d6b00f1fb23b71963ddf1068f7 81 Gene3D G3DSA:1.10.1200.10 1 67 4.6E-14 T 28-03-2018 CPF12_RS11515 385cabbf1237cfb3dd5e69ee740614fd 191 SUPERFAMILY SSF54637 76 183 8.45E-21 T 28-03-2018 IPR029069 HotDog domain CPF12_RS11515 385cabbf1237cfb3dd5e69ee740614fd 191 Gene3D G3DSA:3.10.129.10 33 188 4.7E-21 T 28-03-2018 CPF12_RS11515 385cabbf1237cfb3dd5e69ee740614fd 191 PIRSF PIRSF037733 1 191 1.1E-75 T 28-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 Gene3D G3DSA:1.10.274.10 27 135 5.4E-37 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 6 566 2.8E-237 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 SUPERFAMILY SSF51621 250 551 8.64E-107 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 542 2.6E-123 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 SUPERFAMILY SSF47831 25 144 1.57E-35 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 PIRSF PIRSF000732 1 572 8.0E-222 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 Pfam PF05524 PEP-utilising enzyme, N-terminal 7 127 1.6E-34 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 Gene3D G3DSA:3.50.30.10 136 255 4.2E-31 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 1.0E-30 T 28-03-2018 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 449 464 1.0E-30 T 28-03-2018 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 1.0E-30 T 28-03-2018 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 1.0E-30 T 28-03-2018 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 4.1E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 SUPERFAMILY SSF52009 126 246 1.7E-37 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 Gene3D G3DSA:3.20.20.60 256 572 3.1E-100 T 28-03-2018 CPF12_RS08575 f547f52d87af4ae409413159334f01e7 572 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 449 467 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 Pfam PF12848 ABC transporter 226 304 1.1E-10 T 28-03-2018 IPR032781 ABC-transporter extension domain CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 Gene3D G3DSA:3.40.50.300 1 286 2.2E-55 T 28-03-2018 CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 Pfam PF00005 ABC transporter 20 187 1.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 Pfam PF00005 ABC transporter 338 470 9.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 SUPERFAMILY SSF52540 312 532 2.13E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 SUPERFAMILY SSF52540 128 253 5.61E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 SUPERFAMILY SSF52540 4 83 5.61E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 Gene3D G3DSA:3.40.50.300 287 555 6.8E-52 T 28-03-2018 CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 SMART SM00382 28 248 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 SMART SM00382 344 515 1.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10555 6db042f9b562d8da71f9544991fa7f8f 632 Pfam PF16326 ABC transporter C-terminal domain 563 627 1.3E-12 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 Pfam PF13932 GidA associated domain 402 616 7.2E-79 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 621 1.5E-288 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 SUPERFAMILY SSF51905 8 68 4.33E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 SUPERFAMILY SSF51905 99 262 4.33E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.3E-6 T 28-03-2018 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 2.3E-6 T 28-03-2018 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 SMART SM01228 546 617 8.6E-38 T 28-03-2018 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 Gene3D G3DSA:3.50.50.60 7 266 2.2E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 Pfam PF01134 Glucose inhibited division protein A 10 400 1.2E-169 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CPF12_RS05470 6dad1f7ae0fab3dc276cc1debab6c5b7 631 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 624 42.296 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 3.4E-70 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 SUPERFAMILY SSF54211 2 130 3.22E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 SUPERFAMILY SSF54980 134 199 5.47E-10 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 Gene3D G3DSA:3.30.70.240 135 198 6.9E-13 T 28-03-2018 CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 Gene3D G3DSA:3.30.230.30 4 133 3.1E-45 T 28-03-2018 IPR001498 Impact, N-terminal CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 Pfam PF01205 Uncharacterized protein family UPF0029 19 124 4.5E-32 T 28-03-2018 IPR001498 Impact, N-terminal CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CPF12_RS06615 3006774dc0a8f9f01d384dc0dee42e2a 212 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 4.6E-12 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CPF12_RS07605 45603d36079e3b8ec12a8a5808a7ae32 129 Pfam PF11337 Protein of unknown function (DUF3139) 15 86 2.8E-8 T 28-03-2018 IPR021486 Protein of unknown function DUF3139 CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 Gene3D G3DSA:3.40.50.1820 2 336 2.6E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 SUPERFAMILY SSF53474 3 342 3.83E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 SMART SM00939 308 539 1.8E-57 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 Gene3D G3DSA:2.60.120.260 337 543 6.9E-53 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 12 543 4.9E-128 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 SUPERFAMILY SSF49785 334 543 1.76E-52 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 324 538 1.3E-36 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CPF12_RS05570 f87c57ee1303f2d7274d8d996b3f4c91 545 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 15 284 7.4E-58 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 Gene3D G3DSA:3.40.50.2000 174 346 1.6E-31 T 28-03-2018 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 357 3.1E-103 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 SUPERFAMILY SSF53756 1 361 7.75E-112 T 28-03-2018 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 34.635 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 354 5.0E-46 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 143 2.2E-45 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CPF12_RS02015 42fdc95a86ce40771ed9dbaf318472a7 363 Gene3D G3DSA:3.40.50.2000 1 173 2.3E-39 T 28-03-2018 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Pfam PF09371 Tex-like protein N-terminal domain 10 192 7.4E-65 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Gene3D G3DSA:1.10.10.650 2 101 2.5E-32 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Pfam PF00575 S1 RNA binding domain 643 714 1.2E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SUPERFAMILY SSF47781 552 627 8.9E-15 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SUPERFAMILY SSF158832 5 312 5.49E-108 T 28-03-2018 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SUPERFAMILY SSF47781 462 550 1.22E-27 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SUPERFAMILY SSF53098 314 461 1.18E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Gene3D G3DSA:2.40.50.140 635 718 8.4E-24 T 28-03-2018 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SUPERFAMILY SSF50249 631 718 3.66E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Gene3D G3DSA:1.10.150.310 491 625 7.5E-43 T 28-03-2018 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Pfam PF12836 Helix-hairpin-helix motif 483 547 2.0E-25 T 28-03-2018 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Gene3D G3DSA:1.10.3500.10 351 490 2.9E-41 T 28-03-2018 IPR023323 Tex-like domain CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Gene3D G3DSA:1.10.3500.10 102 350 5.4E-76 T 28-03-2018 IPR023323 Tex-like domain CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SMART SM00316 644 715 1.8E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 Pfam PF16921 Tex protein YqgF-like domain 318 443 1.8E-55 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CPF12_RS09065 239cf8679cf0a1f31c6a66ab0318af0c 721 SMART SM00732 318 416 2.7E-31 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 SMART SM01086 312 407 6.4E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 305 9.7E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 SUPERFAMILY SSF52540 58 399 1.37E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 407 2.3E-201 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 SMART SM00382 110 272 7.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 SMART SM00994 9 48 7.4E-25 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 Gene3D G3DSA:3.40.50.300 58 310 4.7E-70 T 28-03-2018 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 388 1.6E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 Pfam PF06689 ClpX C4-type zinc finger 11 47 5.3E-21 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 SUPERFAMILY SSF57716 10 45 7.7E-12 T 28-03-2018 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 52.416 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CPF12_RS01140 d763f0adb2b0e2d584a5b32cd6a3a4a1 417 Gene3D G3DSA:1.10.8.60 312 404 2.6E-31 T 28-03-2018 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 SUPERFAMILY SSF52833 1 155 9.18E-57 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 PIRSF PIRSF000303 1 155 2.3E-65 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 Pfam PF00255 Glutathione peroxidase 3 109 6.1E-43 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 Gene3D G3DSA:3.40.30.10 1 155 6.5E-47 T 28-03-2018 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 PRINTS PR01011 Glutathione peroxidase family signature 118 127 1.7E-16 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.7E-16 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CPF12_RS02690 5f29f3c20f627e927cb7a1db2efedd57 155 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.7E-16 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CPF12_RS02480 35ca16c0e19da6ea10d428e3c338930e 273 Gene3D G3DSA:1.10.3720.10 3 261 2.2E-42 T 28-03-2018 CPF12_RS02480 35ca16c0e19da6ea10d428e3c338930e 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 264 2.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02480 35ca16c0e19da6ea10d428e3c338930e 273 SUPERFAMILY SSF161098 7 273 2.99E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 SMART SM00448 1 112 1.5E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 Pfam PF00072 Response regulator receiver domain 3 112 1.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 Pfam PF04397 LytTr DNA-binding domain 141 237 1.6E-30 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 SUPERFAMILY SSF52172 1 156 4.27E-28 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 Gene3D G3DSA:3.40.50.2300 1 133 3.1E-28 T 28-03-2018 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 Gene3D G3DSA:2.40.50.40 134 201 1.5E-15 T 28-03-2018 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 SMART SM00850 141 238 2.5E-36 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS00515 68b1ddc47b5d6050fcbe4d45c668145b 239 Gene3D G3DSA:2.20.25.10 202 238 3.6E-15 T 28-03-2018 CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 PIRSF PIRSF002211 1 60 4.6E-30 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 SUPERFAMILY SSF55129 3 59 1.05E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 Gene3D G3DSA:3.30.1390.20 5 59 1.4E-25 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 55 4.1E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.682 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06150 8d4a2d6889e075a58272bc9d667f7454 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 4.2E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 Gene3D G3DSA:3.40.47.10 266 385 1.4E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 ProSitePatterns PS00737 Thiolases signature 2. 334 350 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 SUPERFAMILY SSF53901 267 386 6.81E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 SUPERFAMILY SSF53901 3 262 1.96E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 Pfam PF00108 Thiolase, N-terminal domain 4 257 1.5E-95 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 385 4.9E-141 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 Gene3D G3DSA:3.40.47.10 1 265 4.5E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 Pfam PF02803 Thiolase, C-terminal domain 267 386 8.5E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 ProSitePatterns PS00099 Thiolases active site. 369 382 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CPF12_RS01550 a2acf91e6749ca128211a507865992c9 388 PIRSF PIRSF000429 1 388 3.6E-129 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 179 4.7E-19 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 174 2.3E-44 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 Pfam PF01386 Ribosomal L25p family 5 91 4.0E-21 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 13 94 2.0E-18 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 Gene3D G3DSA:2.170.120.20 98 184 1.5E-20 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 Gene3D G3DSA:2.40.240.10 2 93 4.8E-25 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 SUPERFAMILY SSF50715 10 179 2.09E-45 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CPF12_RS05765 224eee6dd17f5674758c99934416955a 205 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 180 25.025 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PIRSF PIRSF038928 1 484 9.9E-229 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 SMART SM01060 10 394 2.1E-290 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 SUPERFAMILY SSF56634 3 483 7.98E-216 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PRINTS PR00067 Catalase signature 107 124 1.7E-72 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PRINTS PR00067 Catalase signature 291 318 1.7E-72 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PRINTS PR00067 Catalase signature 323 349 1.7E-72 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PRINTS PR00067 Catalase signature 126 144 1.7E-72 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PRINTS PR00067 Catalase signature 23 46 1.7E-72 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 PRINTS PR00067 Catalase signature 86 104 1.7E-72 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 Pfam PF00199 Catalase 10 391 5.2E-197 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 Gene3D G3DSA:2.40.180.10 1 360 7.3E-169 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 336 344 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 ProSitePatterns PS00438 Catalase proximal active site signature. 46 62 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS08140 12fb1d12acfa4c6ca96c0a47345512ef 486 Pfam PF06628 Catalase-related immune-responsive 417 478 1.4E-23 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CPF12_RS06540 591392f0b169f7c50077f842ff1814e3 1433 Gene3D G3DSA:2.60.120.260 862 998 1.3E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS06540 591392f0b169f7c50077f842ff1814e3 1433 Gene3D G3DSA:2.60.120.260 1086 1229 7.2E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS06540 591392f0b169f7c50077f842ff1814e3 1433 Gene3D G3DSA:2.60.120.260 48 238 8.2E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS06540 591392f0b169f7c50077f842ff1814e3 1433 SUPERFAMILY SSF49785 867 988 3.91E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS06540 591392f0b169f7c50077f842ff1814e3 1433 Pfam PF02018 Carbohydrate binding domain 866 984 1.7E-9 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CPF12_RS06540 591392f0b169f7c50077f842ff1814e3 1433 Gene3D G3DSA:2.60.120.260 1294 1431 1.7E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 PRINTS PR00125 ATP synthase delta subunit signature 137 152 1.4E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 PRINTS PR00125 ATP synthase delta subunit signature 152 170 1.4E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.4E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 PRINTS PR00125 ATP synthase delta subunit signature 86 100 1.4E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 PRINTS PR00125 ATP synthase delta subunit signature 75 86 1.4E-19 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 Gene3D G3DSA:1.10.520.20 4 107 7.7E-22 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 176 1.5E-42 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 7.1E-45 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 18.46 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06480 29592607cb0faaa88afb08ace17d9c6c 180 SUPERFAMILY SSF47928 5 106 6.02E-24 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06405 38bac99b7138b00cac165450b1b6b9c1 168 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 14 81 3.1E-11 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CPF12_RS06405 38bac99b7138b00cac165450b1b6b9c1 168 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 164 13.077 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CPF12_RS06405 38bac99b7138b00cac165450b1b6b9c1 168 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 93 3.5E-31 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 Gene3D G3DSA:3.40.50.1000 1 253 1.3E-38 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 SUPERFAMILY SSF56784 4 252 1.68E-73 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 PIRSF PIRSF000915 108 253 7.7E-31 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 PIRSF PIRSF000915 1 115 2.6E-29 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 107 4.2E-30 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 2.0E-42 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 Pfam PF13242 HAD-hyrolase-like 179 251 7.5E-20 T 28-03-2018 CPF12_RS07950 e116a1f7f1bc76aaea11425a016b7ac0 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 4.3E-92 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 Pfam PF01713 Smr domain 709 784 4.3E-20 T 28-03-2018 IPR002625 Smr domain CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 PIRSF PIRSF005814 1 784 5.7E-258 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 SUPERFAMILY SSF52540 292 514 2.07E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 SMART SM00534 328 513 2.4E-72 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 Gene3D G3DSA:3.40.50.300 292 557 1.9E-35 T 28-03-2018 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 SMART SM00463 706 784 1.8E-20 T 28-03-2018 IPR002625 Smr domain CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 783 21.361 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 784 1.8E-246 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 SUPERFAMILY SSF48334 16 287 1.26E-26 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 SUPERFAMILY SSF160443 707 783 1.01E-9 T 28-03-2018 IPR002625 Smr domain CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 SMART SM00533 13 315 5.5E-21 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CPF12_RS02350 9c119266d2396fa493f1bdf048271539 784 Pfam PF00488 MutS domain V 331 511 3.5E-35 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS03075 57ab858fd54ccb15d90f290f6ba138df 351 Gene3D G3DSA:3.20.20.30 1 350 2.7E-65 T 28-03-2018 CPF12_RS03075 57ab858fd54ccb15d90f290f6ba138df 351 SUPERFAMILY SSF51679 12 347 4.32E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS03075 57ab858fd54ccb15d90f290f6ba138df 351 Pfam PF00296 Luciferase-like monooxygenase 26 308 1.4E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS05435 5210f9d083614f1a053f32cf588a3835 58 PIRSF PIRSF037263 1 58 3.7E-32 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CPF12_RS05435 5210f9d083614f1a053f32cf588a3835 58 Pfam PF06107 Bacterial protein of unknown function (DUF951) 3 57 8.3E-31 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CPF12_RS03850 5d886881eb7b0c53caad4195a8a85e82 297 SUPERFAMILY SSF53850 192 295 3.12E-23 T 28-03-2018 CPF12_RS03850 5d886881eb7b0c53caad4195a8a85e82 297 Gene3D G3DSA:3.40.190.10 193 297 1.9E-14 T 28-03-2018 CPF12_RS03850 5d886881eb7b0c53caad4195a8a85e82 297 SUPERFAMILY SSF53850 35 190 1.72E-49 T 28-03-2018 CPF12_RS03850 5d886881eb7b0c53caad4195a8a85e82 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 21 175 1.0E-43 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CPF12_RS03850 5d886881eb7b0c53caad4195a8a85e82 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 194 295 3.6E-16 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CPF12_RS03850 5d886881eb7b0c53caad4195a8a85e82 297 Gene3D G3DSA:3.40.190.10 29 192 3.0E-40 T 28-03-2018 CPF12_RS12265 c5eb15d71eda496b349e90e1c65ec758 539 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 183 528 8.4E-97 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CPF12_RS12265 c5eb15d71eda496b349e90e1c65ec758 539 SUPERFAMILY SSF52540 153 311 4.32E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12265 c5eb15d71eda496b349e90e1c65ec758 539 SUPERFAMILY SSF52540 89 123 4.32E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12265 c5eb15d71eda496b349e90e1c65ec758 539 Gene3D G3DSA:3.40.50.300 150 359 1.0E-11 T 28-03-2018 CPF12_RS04925 4b11b1fcc803ed319070a4e85b432aa0 188 SUPERFAMILY SSF51161 37 186 2.63E-42 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS04925 4b11b1fcc803ed319070a4e85b432aa0 188 Gene3D G3DSA:2.160.10.10 11 188 1.2E-39 T 28-03-2018 CPF12_RS04925 4b11b1fcc803ed319070a4e85b432aa0 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 167 3.2E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS04925 4b11b1fcc803ed319070a4e85b432aa0 188 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 141 169 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CPF12_RS02890 c174070fe19aa6006b3a38f1c5ef7f04 119 Hamap MF_01526 UPF0342 protein . 2 113 18.515 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CPF12_RS02890 c174070fe19aa6006b3a38f1c5ef7f04 119 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 108 1.2E-23 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CPF12_RS02890 c174070fe19aa6006b3a38f1c5ef7f04 119 Gene3D G3DSA:1.20.1500.10 4 109 3.9E-27 T 28-03-2018 IPR023378 YheA/YmcA-like domain CPF12_RS02890 c174070fe19aa6006b3a38f1c5ef7f04 119 SUPERFAMILY SSF158622 4 114 7.19E-34 T 28-03-2018 IPR023378 YheA/YmcA-like domain CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 SUPERFAMILY SSF81624 2 142 3.27E-37 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 272 5.3E-101 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 SMART SM00898 2 117 3.4E-42 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 116 2.4E-30 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 223 1.7E-26 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 Gene3D G3DSA:1.10.8.50 127 273 1.0E-47 T 28-03-2018 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 SUPERFAMILY SSF57716 221 273 1.14E-17 T 28-03-2018 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 ProSitePatterns PS01242 Zinc finger FPG-type signature. 248 272 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 Gene3D G3DSA:3.20.190.10 2 126 2.8E-36 T 28-03-2018 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 Pfam PF06827 Zinc finger found in FPG and IleRS 245 273 1.4E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 273 42.044 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 SMART SM01232 133 225 1.1E-40 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CPF12_RS08480 d1e2fbddb1261939926dc17aee480b18 277 SUPERFAMILY SSF46946 132 222 6.54E-29 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 SUPERFAMILY SSF55831 6 319 6.15E-131 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 Gene3D G3DSA:3.30.572.10 2 319 3.0E-131 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 8 319 4.9E-163 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 PRINTS PR00108 Thymidylate synthase family signature 214 240 2.5E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 PRINTS PR00108 Thymidylate synthase family signature 196 211 2.5E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 PRINTS PR00108 Thymidylate synthase family signature 170 189 2.5E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 PRINTS PR00108 Thymidylate synthase family signature 252 269 2.5E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 PRINTS PR00108 Thymidylate synthase family signature 47 68 2.5E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 Pfam PF00303 Thymidylate synthase 8 319 2.2E-120 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 Hamap MF_00008 Thymidylate synthase [thyA]. 6 319 39.506 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10565 566dd236bfa4bd8068319df56b81114b 319 ProSitePatterns PS00091 Thymidylate synthase active site. 181 209 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CPF12_RS10730 419bc3501d716314f30950d5000bb2f5 93 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 83 6.9E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS10730 419bc3501d716314f30950d5000bb2f5 93 Gene3D G3DSA:3.40.50.2300 1 90 1.2E-16 T 28-03-2018 CPF12_RS10730 419bc3501d716314f30950d5000bb2f5 93 SUPERFAMILY SSF52794 1 88 8.37E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 1.1E-154 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 4.1E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.1E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 Gene3D G3DSA:3.40.50.300 1 80 7.3E-8 T 28-03-2018 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 Gene3D G3DSA:1.10.150.300 110 200 6.2E-28 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 SUPERFAMILY SSF52540 3 304 4.88E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.9E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.9E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.9E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.9E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 Gene3D G3DSA:3.10.20.30 266 365 1.6E-44 T 28-03-2018 IPR012675 Beta-grasp domain CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 SUPERFAMILY SSF81271 282 362 1.22E-35 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 44.773 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CPF12_RS05410 3b3743d7b5a8bc459218a9d79e188465 366 PIRSF PIRSF006641 1 366 3.8E-160 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CPF12_RS04330 1a8ba4f5a54f26719cda5831a5e10bb0 370 Pfam PF13343 Bacterial extracellular solute-binding protein 104 350 4.9E-33 T 28-03-2018 CPF12_RS04330 1a8ba4f5a54f26719cda5831a5e10bb0 370 Gene3D G3DSA:3.40.190.10 170 313 2.9E-15 T 28-03-2018 CPF12_RS04330 1a8ba4f5a54f26719cda5831a5e10bb0 370 SUPERFAMILY SSF53850 61 352 8.69E-40 T 28-03-2018 CPF12_RS04330 1a8ba4f5a54f26719cda5831a5e10bb0 370 Gene3D G3DSA:3.40.190.10 4 169 1.3E-11 T 28-03-2018 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 SUPERFAMILY SSF46894 137 209 5.44E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.7E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 Gene3D G3DSA:3.40.50.2300 1 126 5.3E-32 T 28-03-2018 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 SUPERFAMILY SSF52172 3 134 8.11E-31 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 Gene3D G3DSA:1.10.10.10 127 210 1.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 SMART SM00421 146 203 7.3E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 Pfam PF00072 Response regulator receiver domain 4 115 3.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS01435 c77f4212971c02e35a21017255c378d5 210 SMART SM00448 2 115 2.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 SUPERFAMILY SSF53092 2 126 3.66E-25 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 Gene3D G3DSA:3.90.230.10 114 352 2.7E-78 T 28-03-2018 CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 Gene3D G3DSA:3.40.350.10 1 113 2.7E-30 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 127 1.9E-25 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 Pfam PF00557 Metallopeptidase family M24 136 336 5.0E-64 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CPF12_RS01510 9932645b44da2f2b1ec97272028f141d 353 SUPERFAMILY SSF55920 85 348 9.42E-81 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS02105 ae5c4aadac27223b5575e600571fb6ac 302 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 77 99 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site CPF12_RS02105 ae5c4aadac27223b5575e600571fb6ac 302 Pfam PF01040 UbiA prenyltransferase family 35 284 1.3E-58 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CPF12_RS02105 ae5c4aadac27223b5575e600571fb6ac 302 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 17 300 17.812 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CPF12_RS02105 ae5c4aadac27223b5575e600571fb6ac 302 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 19 297 7.9E-88 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 SUPERFAMILY SSF52467 194 357 2.8E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 SUPERFAMILY SSF52518 13 175 2.99E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 SUPERFAMILY SSF52518 374 552 4.0E-55 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 542 8.1E-41 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 14 553 3.9E-249 T 28-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 Gene3D G3DSA:3.40.50.1220 198 353 9.9E-27 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 Gene3D G3DSA:3.40.50.970 354 557 9.9E-38 T 28-03-2018 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 Gene3D G3DSA:3.40.50.970 6 197 5.5E-45 T 28-03-2018 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 175 4.9E-47 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS11040 7391a956a1233a17a025c9daf666b4f6 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 332 5.1E-28 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 Pfam PF00005 ABC transporter 20 162 3.1E-38 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 Pfam PF08402 TOBE domain 258 334 1.3E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 SUPERFAMILY SSF52540 4 241 3.55E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 SUPERFAMILY SSF50331 257 333 1.7E-6 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 SMART SM00382 29 214 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 Gene3D G3DSA:3.40.50.300 1 249 5.1E-77 T 28-03-2018 CPF12_RS04310 b59f46b6adcde7b0c472cf5de2c4508e 337 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 170 2.2E-44 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 SUPERFAMILY SSF52518 1 171 7.36E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 Gene3D G3DSA:3.40.50.970 344 545 7.7E-41 T 28-03-2018 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 SUPERFAMILY SSF52518 358 548 1.03E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 SUPERFAMILY SSF52467 188 353 2.45E-44 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 527 4.0E-38 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 320 8.7E-35 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 418 437 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 Gene3D G3DSA:3.40.50.970 1 186 6.4E-43 T 28-03-2018 CPF12_RS03250 5c82d4e8415bfa3d989584c310307c91 576 Gene3D G3DSA:3.40.50.1220 187 343 6.4E-37 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 SUPERFAMILY SSF55347 136 288 2.35E-17 T 28-03-2018 CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 Gene3D G3DSA:3.30.360.10 137 329 8.4E-28 T 28-03-2018 CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 239 1.4E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 1 337 50.29 T 28-03-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 SUPERFAMILY SSF51735 3 154 1.83E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 125 1.9E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CPF12_RS10995 53a2dec663c82f93436ea4c4fe78bf07 337 Gene3D G3DSA:3.40.50.720 2 136 7.3E-31 T 28-03-2018 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 Pfam PF00557 Metallopeptidase family M24 146 348 1.3E-62 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 Gene3D G3DSA:3.90.230.10 122 365 2.8E-77 T 28-03-2018 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 SUPERFAMILY SSF55920 95 359 3.01E-78 T 28-03-2018 IPR000994 Peptidase M24 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 8.3E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 8.3E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 8.3E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 Gene3D G3DSA:3.40.350.10 3 121 4.7E-24 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 SUPERFAMILY SSF53092 2 136 9.07E-34 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CPF12_RS08405 962483f17ea504e3bd4f609b7209770e 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 138 6.9E-27 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CPF12_RS02675 5c5a85e6858eb8b424c8774f619b4f57 226 PIRSF PIRSF029008 1 226 6.2E-73 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CPF12_RS02675 5c5a85e6858eb8b424c8774f619b4f57 226 Hamap MF_01124 Adapter protein MecA [mecA]. 1 224 26.064 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CPF12_RS02675 5c5a85e6858eb8b424c8774f619b4f57 226 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 220 1.2E-51 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CPF12_RS07495 56756bedece6331fa230ff676015fd33 307 Gene3D G3DSA:3.40.50.1980 145 307 4.1E-23 T 28-03-2018 CPF12_RS07495 56756bedece6331fa230ff676015fd33 307 Gene3D G3DSA:3.40.50.1980 24 144 2.2E-21 T 28-03-2018 CPF12_RS07495 56756bedece6331fa230ff676015fd33 307 SUPERFAMILY SSF53807 39 299 4.71E-46 T 28-03-2018 CPF12_RS07495 56756bedece6331fa230ff676015fd33 307 Pfam PF01497 Periplasmic binding protein 69 279 8.1E-28 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CPF12_RS03065 0b7dff4d28c18c8b1db28e0581a88c95 392 SUPERFAMILY SSF103473 2 385 2.35E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS03065 0b7dff4d28c18c8b1db28e0581a88c95 392 Gene3D G3DSA:1.20.1250.20 4 192 9.1E-29 T 28-03-2018 CPF12_RS03065 0b7dff4d28c18c8b1db28e0581a88c95 392 Gene3D G3DSA:1.20.1250.20 204 392 1.1E-22 T 28-03-2018 CPF12_RS03065 0b7dff4d28c18c8b1db28e0581a88c95 392 Pfam PF07690 Major Facilitator Superfamily 16 235 1.7E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS07225 dba710331b6d759fbb9dc496392e66af 366 Gene3D G3DSA:1.10.150.130 42 161 1.3E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CPF12_RS07225 dba710331b6d759fbb9dc496392e66af 366 SUPERFAMILY SSF56349 53 354 1.03E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS07225 dba710331b6d759fbb9dc496392e66af 366 Pfam PF00589 Phage integrase family 189 349 2.3E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS07225 dba710331b6d759fbb9dc496392e66af 366 Gene3D G3DSA:1.10.443.10 166 355 5.4E-28 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 Gene3D G3DSA:1.20.1110.10 140 416 6.4E-36 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF56784 490 690 5.36E-47 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF56784 393 412 5.36E-47 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF81653 197 294 5.23E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 144 695 4.8E-169 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 Gene3D G3DSA:3.30.70.100 3 74 9.4E-6 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 Gene3D G3DSA:3.40.1110.10 417 519 5.4E-13 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 Gene3D G3DSA:3.40.50.1000 520 659 2.7E-34 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00941 Cadmium-transporting ATPase signature 125 137 2.0E-16 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00941 Cadmium-transporting ATPase signature 179 199 2.0E-16 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00941 Cadmium-transporting ATPase signature 279 293 2.0E-16 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00941 Cadmium-transporting ATPase signature 15 36 2.0E-16 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00941 Cadmium-transporting ATPase signature 260 276 2.0E-16 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00941 Cadmium-transporting ATPase signature 4 13 2.0E-16 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 Pfam PF00122 E1-E2 ATPase 195 373 1.3E-54 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 168 677 1.4E-82 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 394 408 1.2E-23 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 244 258 1.2E-23 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 593 612 1.2E-23 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 518 529 1.2E-23 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 551 1.2E-23 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 628 1.2E-23 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 396 402 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF55008 5 63 1.05E-6 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 Pfam PF00702 haloacid dehalogenase-like hydrolase 393 606 5.8E-35 T 28-03-2018 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF81665 127 198 5.75E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF81665 295 388 5.75E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS06725 d5298c17a4914cf901a7bd7b475dbca6 713 SUPERFAMILY SSF81665 642 683 5.75E-21 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS04995 695b6708ead48be57426ec21617b7d0a 220 SMART SM00382 28 212 4.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04995 695b6708ead48be57426ec21617b7d0a 220 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS04995 695b6708ead48be57426ec21617b7d0a 220 SUPERFAMILY SSF52540 2 215 3.47E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04995 695b6708ead48be57426ec21617b7d0a 220 Gene3D G3DSA:3.40.50.300 1 219 1.7E-59 T 28-03-2018 CPF12_RS04995 695b6708ead48be57426ec21617b7d0a 220 Pfam PF00005 ABC transporter 20 165 1.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02285 c1c826616560b326b304e0e9132db8bb 234 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 219 3.3E-48 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CPF12_RS02285 c1c826616560b326b304e0e9132db8bb 234 Gene3D G3DSA:3.30.420.40 1 136 6.8E-34 T 28-03-2018 CPF12_RS02285 c1c826616560b326b304e0e9132db8bb 234 Pfam PF00814 Glycoprotease family 31 150 5.4E-30 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02285 c1c826616560b326b304e0e9132db8bb 234 SUPERFAMILY SSF53067 1 102 1.25E-26 T 28-03-2018 CPF12_RS02285 c1c826616560b326b304e0e9132db8bb 234 SUPERFAMILY SSF53067 108 217 2.98E-11 T 28-03-2018 CPF12_RS03115 90999cdaeed07cec6a5159e6afa88830 164 SUPERFAMILY SSF55729 4 142 5.41E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS03115 90999cdaeed07cec6a5159e6afa88830 164 Gene3D G3DSA:3.40.630.30 5 162 1.3E-12 T 28-03-2018 CPF12_RS03115 90999cdaeed07cec6a5159e6afa88830 164 Pfam PF00583 Acetyltransferase (GNAT) family 45 135 6.8E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS05430 8612d4721340b3e1cd2c587c5a6a88d2 318 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 231 5.4E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CPF12_RS05430 8612d4721340b3e1cd2c587c5a6a88d2 318 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 231 7.5E-45 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CPF12_RS07110 609c623465740428ccecf26b6610351e 196 SUPERFAMILY SSF50891 15 117 3.65E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS07110 609c623465740428ccecf26b6610351e 196 SUPERFAMILY SSF50891 146 195 3.65E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS07110 609c623465740428ccecf26b6610351e 196 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 51 68 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 30 45 1.0E-19 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 98 113 1.0E-19 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 56 68 1.0E-19 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 17 193 8.4E-52 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 PIRSF PIRSF001467 5 125 1.2E-43 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 PIRSF PIRSF001467 144 196 6.0E-11 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CPF12_RS07110 609c623465740428ccecf26b6610351e 196 Gene3D G3DSA:2.40.100.10 3 196 7.5E-70 T 28-03-2018 IPR029000 Cyclophilin-like domain CPF12_RS11770 19b13b9e17b8cc2c366865aa9a1a6734 95 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 55 1.2E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11770 19b13b9e17b8cc2c366865aa9a1a6734 95 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11770 19b13b9e17b8cc2c366865aa9a1a6734 95 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11770 19b13b9e17b8cc2c366865aa9a1a6734 95 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11770 19b13b9e17b8cc2c366865aa9a1a6734 95 SUPERFAMILY SSF46785 7 80 3.99E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11770 19b13b9e17b8cc2c366865aa9a1a6734 95 Gene3D G3DSA:1.10.10.10 3 91 6.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 Hamap MF_00300 Chorismate synthase [aroC]. 1 371 35.389 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 1.1E-128 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 Gene3D G3DSA:3.60.150.10 1 389 1.2E-135 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 ProSitePatterns PS00789 Chorismate synthase signature 3. 338 354 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 PIRSF PIRSF001456 1 385 1.2E-126 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 SUPERFAMILY SSF103263 1 387 4.32E-143 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS09520 9ff015634699c0f4e6c1001653d5b3d8 389 Pfam PF01264 Chorismate synthase 1 364 1.9E-118 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CPF12_RS03925 911ba05d2c85eb00146ed868d5b35e7d 556 Gene3D G3DSA:3.10.105.10 311 527 1.4E-39 T 28-03-2018 CPF12_RS03925 911ba05d2c85eb00146ed868d5b35e7d 556 SUPERFAMILY SSF53850 45 547 5.25E-99 T 28-03-2018 CPF12_RS03925 911ba05d2c85eb00146ed868d5b35e7d 556 Gene3D G3DSA:3.90.76.10 52 212 3.8E-32 T 28-03-2018 CPF12_RS03925 911ba05d2c85eb00146ed868d5b35e7d 556 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 472 1.4E-64 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CPF12_RS03925 911ba05d2c85eb00146ed868d5b35e7d 556 Gene3D G3DSA:3.40.190.10 213 310 3.3E-17 T 28-03-2018 CPF12_RS03925 911ba05d2c85eb00146ed868d5b35e7d 556 PIRSF PIRSF002741 1 553 1.8E-79 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CPF12_RS10755 633a3f8fe41a91d6e7541bb93fdd6781 242 SUPERFAMILY SSF54001 108 238 4.25E-14 T 28-03-2018 CPF12_RS10755 633a3f8fe41a91d6e7541bb93fdd6781 242 Gene3D G3DSA:3.90.1720.10 86 241 1.7E-10 T 28-03-2018 CPF12_RS01725 aba7f858517b7dfee0f9a366af44d9e8 180 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 178 4.0E-48 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CPF12_RS01725 aba7f858517b7dfee0f9a366af44d9e8 180 SUPERFAMILY SSF100950 4 178 5.3E-45 T 28-03-2018 CPF12_RS01725 aba7f858517b7dfee0f9a366af44d9e8 180 PIRSF PIRSF006806 1 180 6.9E-47 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CPF12_RS01725 aba7f858517b7dfee0f9a366af44d9e8 180 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 177 3.2E-41 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CPF12_RS01725 aba7f858517b7dfee0f9a366af44d9e8 180 Gene3D G3DSA:3.40.50.10420 1 180 2.1E-48 T 28-03-2018 CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 SMART SM00739 2 29 1.5E-6 T 28-03-2018 IPR005824 KOW CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 SUPERFAMILY SSF50104 1 100 8.65E-39 T 28-03-2018 IPR008991 Translation protein SH3-like domain CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 Gene3D G3DSA:2.30.30.30 1 92 4.1E-39 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 5.6E-30 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 5.4E-40 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 22.852 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06115 f4d91389239108dee5700d6145e3a310 102 Pfam PF00467 KOW motif 5 36 3.9E-9 T 28-03-2018 IPR005824 KOW CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 Gene3D G3DSA:3.40.50.300 165 448 1.1E-77 T 28-03-2018 CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 SUPERFAMILY SSF52540 181 434 1.3E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 Pfam PF03796 DnaB-like helicase C terminal domain 183 440 2.3E-118 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 8 442 2.8E-180 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 Pfam PF00772 DnaB-like helicase N terminal domain 8 109 1.0E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 Gene3D G3DSA:1.10.860.10 1 149 3.9E-45 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CPF12_RS05350 1a26f902a206b99c88e26b5c85c0cc4d 454 SUPERFAMILY SSF48024 6 118 3.79E-36 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CPF12_RS04730 bce68d153880a840dd5383c3bf902628 485 Gene3D G3DSA:3.40.50.2300 391 481 2.5E-5 T 28-03-2018 CPF12_RS04730 bce68d153880a840dd5383c3bf902628 485 Pfam PF05043 Mga helix-turn-helix domain 74 156 6.1E-16 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS04730 bce68d153880a840dd5383c3bf902628 485 Gene3D G3DSA:1.10.10.10 76 145 8.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04730 bce68d153880a840dd5383c3bf902628 485 Gene3D G3DSA:1.10.10.10 6 64 1.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08335 0a9bdd4faa151c6666254068206fb26d 125 SUPERFAMILY SSF54637 4 124 2.8E-29 T 28-03-2018 IPR029069 HotDog domain CPF12_RS08335 0a9bdd4faa151c6666254068206fb26d 125 Gene3D G3DSA:3.10.129.10 2 123 1.4E-26 T 28-03-2018 CPF12_RS08335 0a9bdd4faa151c6666254068206fb26d 125 Pfam PF03061 Thioesterase superfamily 35 111 4.0E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CPF12_RS08335 0a9bdd4faa151c6666254068206fb26d 125 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 5 120 9.7E-31 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CPF12_RS11430 fdef00ba5f916792d2045a8ca5f33bf0 567 Pfam PF05670 Domain of unknown function (DUF814) 451 535 1.7E-25 T 28-03-2018 IPR008532 Domain of unknown function DUF814 CPF12_RS11430 fdef00ba5f916792d2045a8ca5f33bf0 567 Gene3D G3DSA:3.40.970.40 238 286 1.1E-12 T 28-03-2018 CPF12_RS11430 fdef00ba5f916792d2045a8ca5f33bf0 567 Gene3D G3DSA:2.30.310.10 1 167 8.2E-51 T 28-03-2018 CPF12_RS11430 fdef00ba5f916792d2045a8ca5f33bf0 567 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 441 4.9E-146 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 1.6E-109 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 418 28.217 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Gene3D G3DSA:3.30.420.40 195 256 0.0019 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Gene3D G3DSA:3.30.420.40 257 348 3.2E-16 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 SUPERFAMILY SSF53067 197 368 2.72E-39 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Pfam PF14450 Cell division protein FtsA 205 366 2.3E-21 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Pfam PF14450 Cell division protein FtsA 9 188 1.0E-11 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 PIRSF PIRSF003101 1 418 3.9E-133 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Gene3D G3DSA:3.30.420.40 4 130 7.8E-29 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 Pfam PF02491 SHS2 domain inserted in FTSA 86 160 1.5E-20 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 SUPERFAMILY SSF53067 5 195 2.25E-56 T 28-03-2018 CPF12_RS02005 78b833b2dc8ac73eb972d240bbfc6611 419 SMART SM00842 7 194 4.3E-81 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CPF12_RS01230 7ae148237b15293e18c6b5b3bcfd48d2 94 Pfam PF09862 Protein of unknown function (DUF2089) 2 79 5.2E-16 T 28-03-2018 IPR018658 Protein of unknown function DUF2089 CPF12_RS01230 7ae148237b15293e18c6b5b3bcfd48d2 94 Gene3D G3DSA:1.10.10.10 2 61 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 SUPERFAMILY SSF100920 354 510 2.09E-59 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 3.0E-278 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 Gene3D G3DSA:1.20.1270.10 502 588 9.6E-21 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 603 36.366 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 Gene3D G3DSA:2.60.34.10 360 501 3.3E-64 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 112 132 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 304 320 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 53 61 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 358 377 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 172 182 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 439 455 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 335 355 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.7E-77 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 Pfam PF00012 Hsp70 protein 4 573 4.0E-239 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 SUPERFAMILY SSF53067 1 157 4.05E-57 T 28-03-2018 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 Gene3D G3DSA:3.30.420.40 1 170 7.1E-66 T 28-03-2018 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 SUPERFAMILY SSF100934 477 575 1.18E-15 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 SUPERFAMILY SSF53067 160 351 4.18E-67 T 28-03-2018 CPF12_RS09290 a87d646ce4ce5321e83aeb498ecadca8 612 Gene3D G3DSA:3.30.420.40 171 331 7.1E-50 T 28-03-2018 CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 SUPERFAMILY SSF50249 2 63 1.5E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 291 35.909 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 Pfam PF16745 RsgA N-terminal domain 3 57 2.2E-25 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 40 285 1.2E-72 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 Gene3D G3DSA:3.40.50.300 63 227 4.8E-22 T 28-03-2018 CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 Gene3D G3DSA:2.40.50.140 1 61 2.2E-21 T 28-03-2018 CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 SUPERFAMILY SSF52540 66 289 2.86E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 Gene3D G3DSA:1.10.40.50 229 294 6.0E-19 T 28-03-2018 CPF12_RS11475 e64c43523cc0b9fc30cd412fab5766bf 294 Pfam PF03193 RsgA GTPase 62 227 2.2E-54 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CPF12_RS11095 811b0cb78131d2f89fedab35660ff204 155 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 26 151 8.3E-34 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CPF12_RS11095 811b0cb78131d2f89fedab35660ff204 155 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 11 154 26.522 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 Hamap MF_01685 Ferredoxin--NADP reductase. 6 328 34.822 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 SUPERFAMILY SSF51905 1 315 3.76E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 Gene3D G3DSA:3.50.50.60 248 341 9.0E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 290 6.8E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 Gene3D G3DSA:3.50.50.60 132 244 2.4E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.5E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 3.5E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 3.5E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 111 119 3.5E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 201 217 3.5E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 1.2E-17 T 28-03-2018 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.2E-17 T 28-03-2018 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.2E-17 T 28-03-2018 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.2E-17 T 28-03-2018 CPF12_RS07505 0d7145e465644a4f9e368cd4451645c0 344 Gene3D G3DSA:3.50.50.60 6 131 2.5E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02165 3228dca303cb036cd473e01cc88fe9b0 89 SUPERFAMILY SSF158504 5 88 5.62E-30 T 28-03-2018 IPR023324 BH2638-like domain CPF12_RS02165 3228dca303cb036cd473e01cc88fe9b0 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 4 89 5.0E-20 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CPF12_RS02165 3228dca303cb036cd473e01cc88fe9b0 89 PIRSF PIRSF037260 1 89 1.7E-34 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CPF12_RS02165 3228dca303cb036cd473e01cc88fe9b0 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 3 85 7.0E-33 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CPF12_RS02165 3228dca303cb036cd473e01cc88fe9b0 89 Gene3D G3DSA:1.10.220.80 13 89 1.2E-28 T 28-03-2018 IPR023324 BH2638-like domain CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 Pfam PF01047 MarR family 36 95 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 7.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 7.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 7.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 SMART SM00347 29 131 3.5E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 SUPERFAMILY SSF46785 13 143 1.02E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07685 e95ed6bb53402cda65b9cbb7ff09e556 149 Gene3D G3DSA:1.10.10.10 1 149 5.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 Gene3D G3DSA:3.30.360.10 191 488 2.3E-112 T 28-03-2018 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 SUPERFAMILY SSF55347 184 486 2.88E-103 T 28-03-2018 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 8 486 1.8E-170 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 4.6E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 4.6E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 4.6E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 4.6E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 4.6E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 485 1.3E-102 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 SUPERFAMILY SSF51735 6 187 4.72E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 8 487 77.545 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 PIRSF PIRSF000110 1 489 9.2E-176 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 179 185 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 189 9.8E-59 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CPF12_RS11060 abdc222a1e4d36666e5a5b4deaef27a2 489 Gene3D G3DSA:3.40.50.720 6 190 1.8E-63 T 28-03-2018 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 SUPERFAMILY SSF46589 1 113 2.56E-29 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 Gene3D G3DSA:3.30.930.10 106 424 4.0E-95 T 28-03-2018 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 4.4E-171 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 7.0E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 41.332 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.2E-30 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 6.8E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 6.8E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 6.8E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 6.8E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 6.8E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 PIRSF PIRSF001529 1 424 2.6E-183 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 SUPERFAMILY SSF55681 117 418 8.29E-101 T 28-03-2018 CPF12_RS05580 0889f56010ab956649857fb1a351eb9b 424 Gene3D G3DSA:1.10.287.40 2 105 1.1E-24 T 28-03-2018 CPF12_RS08300 e60267c0e49b869c003994b8b25468f5 451 SUPERFAMILY SSF51998 2 446 1.37E-183 T 28-03-2018 CPF12_RS08300 e60267c0e49b869c003994b8b25468f5 451 Pfam PF05167 Uncharacterised ACR (DUF711) 12 415 3.6E-184 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 CPF12_RS08300 e60267c0e49b869c003994b8b25468f5 451 Hamap MF_01221 UPF0210 protein . 1 451 53.361 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 CPF12_RS08300 e60267c0e49b869c003994b8b25468f5 451 Gene3D G3DSA:3.20.70.20 13 428 5.2E-187 T 28-03-2018 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 Gene3D G3DSA:1.10.10.10 1 83 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.0E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 Gene3D G3DSA:3.40.190.10 88 203 1.4E-11 T 28-03-2018 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 SUPERFAMILY SSF46785 3 82 4.58E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 SUPERFAMILY SSF53850 92 294 1.49E-14 T 28-03-2018 CPF12_RS11595 422978e70ced8e989e653984eff9b91c 299 Pfam PF03466 LysR substrate binding domain 92 283 8.3E-13 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 TIGRFAM TIGR00836 amt: ammonium transporter 3 393 5.1E-128 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 Gene3D G3DSA:1.10.3430.10 1 374 5.8E-119 T 28-03-2018 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 PRINTS PR00342 Rhesus blood group protein signature 253 266 7.0E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 PRINTS PR00342 Rhesus blood group protein signature 97 113 7.0E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 PRINTS PR00342 Rhesus blood group protein signature 189 207 7.0E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 PRINTS PR00342 Rhesus blood group protein signature 309 325 7.0E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 ProSitePatterns PS01219 Ammonium transporters signature. 154 179 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 Pfam PF00909 Ammonium Transporter Family 6 393 4.0E-115 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CPF12_RS08660 e190dcf44c6e7e3ac5d6e9d7076d42ae 395 SUPERFAMILY SSF111352 2 374 1.09E-118 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CPF12_RS10600 dc2048606ece32342a7469f4f611df6b 245 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 41 233 1.3E-29 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CPF12_RS10600 dc2048606ece32342a7469f4f611df6b 245 SUPERFAMILY SSF52266 34 243 3.21E-39 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CPF12_RS10600 dc2048606ece32342a7469f4f611df6b 245 Gene3D G3DSA:3.40.50.1110 30 245 9.6E-38 T 28-03-2018 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SMART SM00957 1 376 4.4E-167 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Pfam PF07517 SecA DEAD-like domain 5 375 8.8E-96 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SUPERFAMILY SSF81886 566 765 1.19E-36 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Pfam PF01043 SecA preprotein cross-linking domain 227 332 1.3E-30 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SUPERFAMILY SSF52540 342 389 2.59E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SUPERFAMILY SSF52540 8 221 2.59E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Pfam PF07516 SecA Wing and Scaffold domain 562 759 7.3E-37 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Gene3D G3DSA:1.10.3060.10 579 772 2.4E-29 T 28-03-2018 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Gene3D G3DSA:3.40.50.300 391 578 2.3E-37 T 28-03-2018 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SUPERFAMILY SSF81767 224 341 3.4E-37 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 56 80 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 313 335 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 350 367 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 387 400 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 94 108 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 163 183 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 PRINTS PR00906 SecA protein signature 110 120 2.4E-47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SMART SM00958 222 332 3.6E-46 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 SUPERFAMILY SSF52540 394 550 9.78E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 763 16.144 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 ProSitePatterns PS01312 SecA family signature. 474 489 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Gene3D G3DSA:3.40.50.300 2 264 5.8E-40 T 28-03-2018 CPF12_RS03365 c4da667280d04494a1681ceca4f2248e 806 Gene3D G3DSA:3.40.50.300 270 390 6.6E-8 T 28-03-2018 CPF12_RS12450 4d99caa59320d1af88155c2f742925a7 166 SUPERFAMILY SSF52499 7 164 1.7E-34 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CPF12_RS12450 4d99caa59320d1af88155c2f742925a7 166 Pfam PF00857 Isochorismatase family 7 144 8.4E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CPF12_RS12450 4d99caa59320d1af88155c2f742925a7 166 Gene3D G3DSA:3.40.50.850 5 166 2.6E-30 T 28-03-2018 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 PIRSF PIRSF002808 5 448 5.4E-158 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 SUPERFAMILY SSF103473 10 441 7.06E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 34 423 1.8E-145 T 28-03-2018 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 3 443 4.1E-212 T 28-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 Pfam PF07690 Major Facilitator Superfamily 33 404 7.5E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 ProSitePatterns PS00942 glpT family of transporters signature. 152 168 - T 28-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 Gene3D G3DSA:1.20.1250.20 246 447 9.1E-31 T 28-03-2018 CPF12_RS09170 c5e7bc4ccd9d87cdedf1917ba1f61856 448 Gene3D G3DSA:1.20.1250.20 17 231 1.6E-31 T 28-03-2018 CPF12_RS01735 4a47160055524e17e4fdc57f1ef7713c 120 Pfam PF06667 Phage shock protein B 3 65 6.9E-6 T 28-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 Pfam PF07690 Major Facilitator Superfamily 12 267 1.1E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 SUPERFAMILY SSF103473 3 398 2.35E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 PRINTS PR01035 Tetracycline resistance protein signature 106 127 7.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 PRINTS PR01035 Tetracycline resistance protein signature 136 158 7.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 PRINTS PR01035 Tetracycline resistance protein signature 341 364 7.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 PRINTS PR01035 Tetracycline resistance protein signature 79 103 7.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 PRINTS PR01035 Tetracycline resistance protein signature 17 33 7.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 Gene3D G3DSA:1.20.1250.20 3 202 3.5E-37 T 28-03-2018 CPF12_RS07105 8c20b7b6fb660af69ef0a24a51439397 402 Gene3D G3DSA:1.20.1250.20 203 401 1.1E-23 T 28-03-2018 CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 SUPERFAMILY SSF51604 118 361 1.7E-59 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 SMART SM00922 143 235 9.9E-18 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 Pfam PF13378 Enolase C-terminal domain-like 147 353 2.4E-36 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 126 9.8E-9 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 Gene3D G3DSA:3.20.20.120 145 343 5.7E-49 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 Gene3D G3DSA:3.30.390.10 1 144 2.5E-27 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 332 1.1E-102 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 2 360 38.955 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS06530 5042fd1659e2b6d8c497c8a8c7258418 368 SUPERFAMILY SSF54826 2 126 3.4E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CPF12_RS03045 200d70270aa09cfd73a973cefc7c15f6 245 Pfam PF12698 ABC-2 family transporter protein 50 234 1.6E-8 T 28-03-2018 CPF12_RS06260 5be3a72a00f5d5a1bc95fefded247841 281 SUPERFAMILY SSF53697 97 275 4.87E-39 T 28-03-2018 CPF12_RS06260 5be3a72a00f5d5a1bc95fefded247841 281 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 75 3.0E-20 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CPF12_RS06260 5be3a72a00f5d5a1bc95fefded247841 281 SUPERFAMILY SSF46689 6 77 1.97E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS06260 5be3a72a00f5d5a1bc95fefded247841 281 Gene3D G3DSA:3.40.50.10490 79 277 1.1E-35 T 28-03-2018 CPF12_RS06260 5be3a72a00f5d5a1bc95fefded247841 281 Gene3D G3DSA:1.10.10.10 4 78 4.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06260 5be3a72a00f5d5a1bc95fefded247841 281 Pfam PF01380 SIS domain 127 255 9.2E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS12185 b18b01660d04bb38c3d4100824e8cd66 103 Gene3D G3DSA:3.30.1330.30 5 101 3.3E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CPF12_RS12185 b18b01660d04bb38c3d4100824e8cd66 103 SUPERFAMILY SSF55315 6 100 1.88E-25 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CPF12_RS12185 b18b01660d04bb38c3d4100824e8cd66 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 1.0E-14 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CPF12_RS08100 9b23e9fb0b0c2389ce0bd9d5c2edfe99 269 Gene3D G3DSA:1.10.3720.10 7 262 1.5E-34 T 28-03-2018 CPF12_RS08100 9b23e9fb0b0c2389ce0bd9d5c2edfe99 269 SUPERFAMILY SSF161098 4 257 2.22E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04750 297c9422a65acf9d7c6f9cdb90bafb8e 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 98 3.2E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS04750 297c9422a65acf9d7c6f9cdb90bafb8e 106 Gene3D G3DSA:3.40.50.2300 5 106 3.7E-35 T 28-03-2018 CPF12_RS04750 297c9422a65acf9d7c6f9cdb90bafb8e 106 SUPERFAMILY SSF52794 4 105 1.23E-31 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 SUPERFAMILY SSF51445 2 463 1.26E-156 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 8.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 423 8.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 361 369 8.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 8.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 385 396 8.3E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 Gene3D G3DSA:3.20.20.80 4 462 1.5E-138 T 28-03-2018 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 Pfam PF00232 Glycosyl hydrolase family 1 4 462 2.6E-128 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04745 7b63a375e2c33ee51be125fdf089a76e 464 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 361 369 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS09215 2a39cd023bb74d502cc5cd78e3b4ec95 262 Gene3D G3DSA:3.40.1390.30 113 226 7.0E-35 T 28-03-2018 CPF12_RS09215 2a39cd023bb74d502cc5cd78e3b4ec95 262 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 258 2.1E-69 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CPF12_RS09215 2a39cd023bb74d502cc5cd78e3b4ec95 262 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 244 8.7E-74 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CPF12_RS09215 2a39cd023bb74d502cc5cd78e3b4ec95 262 Gene3D G3DSA:3.40.1390.30 1 112 1.0E-33 T 28-03-2018 CPF12_RS09215 2a39cd023bb74d502cc5cd78e3b4ec95 262 SUPERFAMILY SSF102705 1 261 1.03E-82 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 PIRSF PIRSF002599 1 66 2.8E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 PRINTS PR00050 Cold shock protein signature 24 33 1.6E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 PRINTS PR00050 Cold shock protein signature 39 57 1.6E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 Gene3D G3DSA:2.40.50.140 1 66 6.2E-27 T 28-03-2018 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.6E-28 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 SMART SM00357 3 66 9.4E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CPF12_RS01955 359d97b647e9962b36f347048216e94b 66 SUPERFAMILY SSF50249 1 65 3.23E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS01430 2f7bc24522ee997aace77f460ecf9ec5 225 Pfam PF02254 TrkA-N domain 11 126 5.4E-28 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CPF12_RS01430 2f7bc24522ee997aace77f460ecf9ec5 225 Gene3D G3DSA:3.40.50.720 10 141 1.2E-21 T 28-03-2018 CPF12_RS01430 2f7bc24522ee997aace77f460ecf9ec5 225 Pfam PF02080 TrkA-C domain 156 224 1.3E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CPF12_RS01430 2f7bc24522ee997aace77f460ecf9ec5 225 Gene3D G3DSA:3.30.70.1450 142 224 1.5E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CPF12_RS01430 2f7bc24522ee997aace77f460ecf9ec5 225 SUPERFAMILY SSF116726 141 224 2.88E-19 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CPF12_RS01430 2f7bc24522ee997aace77f460ecf9ec5 225 SUPERFAMILY SSF51735 10 140 1.22E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Pfam PF00140 Sigma-70 factor, region 1.2 91 123 1.4E-17 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Pfam PF03979 Sigma-70 factor, region 1.1 14 73 1.4E-10 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 153 166 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 125 361 1.2E-124 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Gene3D G3DSA:1.10.10.10 199 249 1.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Pfam PF04545 Sigma-70, region 4 297 350 4.9E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 SUPERFAMILY SSF88659 202 275 8.41E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 124 350 9.3E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Pfam PF04539 Sigma-70 region 3 208 284 1.0E-31 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Gene3D G3DSA:1.10.601.10 71 198 1.6E-74 T 28-03-2018 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Gene3D G3DSA:1.10.601.10 1 70 0.29 T 28-03-2018 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 SUPERFAMILY SSF88946 90 199 2.88E-53 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 322 348 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Pfam PF04542 Sigma-70 region 2 129 198 3.4E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 PRINTS PR00046 Major sigma-70 factor signature 153 166 2.5E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 PRINTS PR00046 Major sigma-70 factor signature 177 185 2.5E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 PRINTS PR00046 Major sigma-70 factor signature 301 313 2.5E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 PRINTS PR00046 Major sigma-70 factor signature 322 337 2.5E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 PRINTS PR00046 Major sigma-70 factor signature 337 348 2.5E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 6 362 33.929 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 SUPERFAMILY SSF88659 259 360 5.05E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CPF12_RS11105 9afdc64e664f07c2d64afe6f04a8584e 362 Gene3D G3DSA:1.10.10.10 291 362 3.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 Gene3D G3DSA:3.40.640.10 188 307 7.6E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 Gene3D G3DSA:3.90.1150.10 308 435 6.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 SUPERFAMILY SSF53383 6 429 4.55E-129 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 Pfam PF00202 Aminotransferase class-III 38 400 4.1E-78 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 8 428 1.2E-188 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 Gene3D G3DSA:3.90.1150.10 3 187 1.8E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS01130 9a815d15174d928782ebecfca7b9f5fd 437 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 8 429 98.078 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CPF12_RS04510 45accce07a0f2f55bede09def35dd296 443 SUPERFAMILY SSF51679 4 431 5.23E-129 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS04510 45accce07a0f2f55bede09def35dd296 443 Pfam PF00296 Luciferase-like monooxygenase 23 380 1.2E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS04510 45accce07a0f2f55bede09def35dd296 443 PIRSF PIRSF000337 3 440 5.0E-141 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CPF12_RS04510 45accce07a0f2f55bede09def35dd296 443 Gene3D G3DSA:3.20.20.30 1 443 3.5E-96 T 28-03-2018 CPF12_RS04510 45accce07a0f2f55bede09def35dd296 443 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 425 5.6E-160 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 SUPERFAMILY SSF63520 306 398 1.31E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Pfam PF08279 HTH domain 6 61 8.4E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Pfam PF00874 PRD domain 311 398 1.2E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Gene3D G3DSA:1.10.1790.10 299 403 9.4E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 SUPERFAMILY SSF63520 182 290 1.96E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Gene3D G3DSA:1.10.10.10 1 67 2.8E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Gene3D G3DSA:1.10.10.10 85 151 3.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 408 467 1.4E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Gene3D G3DSA:3.40.50.2300 404 495 1.2E-19 T 28-03-2018 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Gene3D G3DSA:1.10.1790.10 181 293 2.8E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 SUPERFAMILY SSF52794 405 491 3.3E-11 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS04920 21cbf8365a3983c2c3caa259c8fffde9 496 Pfam PF05043 Mga helix-turn-helix domain 98 159 1.3E-7 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS02875 4f4778b6fb7de9a15c9658b59fb805ca 317 Gene3D G3DSA:2.40.50.140 12 109 2.4E-8 T 28-03-2018 CPF12_RS02875 4f4778b6fb7de9a15c9658b59fb805ca 317 Pfam PF01966 HD domain 162 278 2.1E-9 T 28-03-2018 IPR006674 HD domain CPF12_RS02875 4f4778b6fb7de9a15c9658b59fb805ca 317 SUPERFAMILY SSF50249 31 96 4.0E-5 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS02875 4f4778b6fb7de9a15c9658b59fb805ca 317 SUPERFAMILY SSF109604 143 278 2.88E-12 T 28-03-2018 CPF12_RS02875 4f4778b6fb7de9a15c9658b59fb805ca 317 Gene3D G3DSA:1.10.3210.10 110 309 3.9E-13 T 28-03-2018 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 108 1.7E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 Pfam PF02378 Phosphotransferase system, EIIC 113 407 1.5E-44 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 Gene3D G3DSA:3.30.1360.60 5 82 1.4E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 SUPERFAMILY SSF55604 8 82 4.45E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 465 2.1E-189 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 Pfam PF00367 phosphotransferase system, EIIB 9 42 1.2E-16 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS06850 ef1bf2c56c3994efb7b626190bfde191 471 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04530 b6d461a00e0e688b724dea3006c5408e 270 Gene3D G3DSA:3.40.1190.20 1 270 1.3E-67 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS04530 b6d461a00e0e688b724dea3006c5408e 270 SUPERFAMILY SSF53613 1 263 1.87E-83 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS04530 b6d461a00e0e688b724dea3006c5408e 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 259 9.9E-97 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CPF12_RS04530 b6d461a00e0e688b724dea3006c5408e 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 1.6E-103 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.1E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 Pfam PF01197 Ribosomal protein L31 1 79 1.8E-29 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 SUPERFAMILY SSF143800 1 80 1.57E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.86 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 3.9E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.9E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 3.9E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06425 5883d05266b11d6f754ca7246ad7c736 81 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS03985 3a1fc1b5ed207b3febdff8395ebded89 232 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 31 229 1.2E-67 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CPF12_RS03985 3a1fc1b5ed207b3febdff8395ebded89 232 Gene3D G3DSA:3.20.20.70 1 232 6.1E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS03985 3a1fc1b5ed207b3febdff8395ebded89 232 SUPERFAMILY SSF51366 9 225 3.06E-54 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS03985 3a1fc1b5ed207b3febdff8395ebded89 232 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 7 229 39.627 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 Gene3D G3DSA:3.40.630.10 1 199 5.5E-43 T 28-03-2018 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 Gene3D G3DSA:3.40.630.10 200 375 6.2E-20 T 28-03-2018 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 1 361 1.2E-109 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 SUPERFAMILY SSF53187 1 183 5.43E-77 T 28-03-2018 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 SUPERFAMILY SSF53187 284 374 5.43E-77 T 28-03-2018 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 Pfam PF01546 Peptidase family M20/M25/M40 58 369 4.0E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 SUPERFAMILY SSF55031 171 277 1.03E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 PIRSF PIRSF005962 1 375 3.7E-118 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS03895 33fbf87cd415169a95d7c4dc5b1e65e2 375 Pfam PF07687 Peptidase dimerisation domain 172 266 2.6E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS09400 de6d89a7af9f4d0b82eb8e2ae2421d21 247 Gene3D G3DSA:1.10.10.580 176 242 1.2E-13 T 28-03-2018 CPF12_RS09400 de6d89a7af9f4d0b82eb8e2ae2421d21 247 Hamap MF_01805 Segregation and condensation protein A [scpA]. 4 245 25.445 T 28-03-2018 IPR003768 Segregation and condensation protein A CPF12_RS09400 de6d89a7af9f4d0b82eb8e2ae2421d21 247 Pfam PF02616 Segregation and condensation protein ScpA 21 243 8.7E-48 T 28-03-2018 IPR003768 Segregation and condensation protein A CPF12_RS00410 899169f543658c89c3c56ab2469ce9bb 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 366 8.4E-86 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CPF12_RS00410 899169f543658c89c3c56ab2469ce9bb 390 Gene3D G3DSA:1.20.1090.10 186 390 9.8E-37 T 28-03-2018 CPF12_RS00410 899169f543658c89c3c56ab2469ce9bb 390 SUPERFAMILY SSF56796 3 385 2.36E-100 T 28-03-2018 CPF12_RS00410 899169f543658c89c3c56ab2469ce9bb 390 Gene3D G3DSA:3.40.50.1970 10 185 8.0E-41 T 28-03-2018 CPF12_RS00410 899169f543658c89c3c56ab2469ce9bb 390 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 175 203 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CPF12_RS03455 d0185d8a953bddd4429b1b93ad6e0c34 154 Gene3D G3DSA:1.10.10.10 1 148 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03455 d0185d8a953bddd4429b1b93ad6e0c34 154 SUPERFAMILY SSF46785 12 146 7.58E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03455 d0185d8a953bddd4429b1b93ad6e0c34 154 SMART SM00347 30 130 1.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS04580 8abcc199538bbbf98d079c4d5ae2b49b 499 Pfam PF02687 FtsX-like permease family 373 494 1.4E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS04580 8abcc199538bbbf98d079c4d5ae2b49b 499 Pfam PF12704 MacB-like periplasmic core domain 29 232 2.6E-7 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Pfam PF14520 Helix-hairpin-helix domain 538 588 2.9E-6 T 28-03-2018 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Gene3D G3DSA:1.10.150.20 529 586 2.4E-11 T 28-03-2018 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 570 4.3E-204 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 1.0E-53 T 28-03-2018 IPR001162 UvrC family homology region CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Pfam PF01541 GIY-YIG catalytic domain 17 90 4.8E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 27.76 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 SUPERFAMILY SSF46600 183 235 2.09E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Gene3D G3DSA:3.40.1440.10 1 98 1.1E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 SUPERFAMILY SSF82771 15 97 1.18E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Gene3D G3DSA:4.10.860.10 175 236 2.7E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 Pfam PF02151 UvrB/uvrC motif 198 229 7.9E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 SUPERFAMILY SSF47781 502 585 1.87E-19 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS02325 0a8f80820d710be2e651ee84887eb487 590 SMART SM00465 15 95 1.3E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS02775 09d1ab3061e224e0d57275e32c91f326 171 SUPERFAMILY SSF52833 9 165 2.91E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS02775 09d1ab3061e224e0d57275e32c91f326 171 Pfam PF13462 Thioredoxin 10 165 1.5E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS02775 09d1ab3061e224e0d57275e32c91f326 171 Gene3D G3DSA:1.10.1200.90 63 121 1.7E-19 T 28-03-2018 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 ProSitePatterns PS00449 ATP synthase a subunit signature. 166 175 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 18 233 1.9E-45 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 SUPERFAMILY SSF81336 70 230 3.4E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 237 13.304 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 PRINTS PR00123 ATP synthase A subunit signature 163 185 1.8E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 PRINTS PR00123 ATP synthase A subunit signature 78 94 1.8E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 PRINTS PR00123 ATP synthase A subunit signature 217 232 1.8E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 Pfam PF00119 ATP synthase A chain 23 230 6.8E-55 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06465 c8e1729133c02daee869b10a02a1c9d4 238 Gene3D G3DSA:1.20.120.220 69 238 3.0E-40 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06875 5941d58870dba1bacf53dc047bc160a4 128 Gene3D G3DSA:3.90.1720.10 3 126 7.8E-9 T 28-03-2018 CPF12_RS06875 5941d58870dba1bacf53dc047bc160a4 128 SUPERFAMILY SSF54001 41 111 2.11E-7 T 28-03-2018 CPF12_RS00735 1a98605f2ce63f4f7b9ea1f25463a265 259 SUPERFAMILY SSF46689 6 78 8.06E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS00735 1a98605f2ce63f4f7b9ea1f25463a265 259 Gene3D G3DSA:1.10.10.10 1 78 4.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00735 1a98605f2ce63f4f7b9ea1f25463a265 259 Gene3D G3DSA:3.40.50.10490 88 259 2.5E-22 T 28-03-2018 CPF12_RS00735 1a98605f2ce63f4f7b9ea1f25463a265 259 Pfam PF01380 SIS domain 121 223 3.3E-14 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS00735 1a98605f2ce63f4f7b9ea1f25463a265 259 SUPERFAMILY SSF53697 95 256 8.71E-28 T 28-03-2018 CPF12_RS00735 1a98605f2ce63f4f7b9ea1f25463a265 259 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 77 1.6E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 Gene3D G3DSA:1.20.272.10 222 332 1.1E-30 T 28-03-2018 CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 Gene3D G3DSA:3.40.50.300 5 141 7.0E-23 T 28-03-2018 CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 SUPERFAMILY SSF52540 12 210 2.55E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 Pfam PF06144 DNA polymerase III, delta subunit 17 191 1.3E-43 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 SUPERFAMILY SSF48019 213 328 5.44E-23 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 326 5.7E-77 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CPF12_RS09785 70f005372f20cc9202bf1d4c21956fd4 334 Gene3D G3DSA:1.10.8.60 144 221 4.4E-18 T 28-03-2018 CPF12_RS09230 5dc313ebe3af2ec338920d009ef514c9 293 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CPF12_RS09230 5dc313ebe3af2ec338920d009ef514c9 293 Pfam PF00348 Polyprenyl synthetase 33 269 4.7E-59 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CPF12_RS09230 5dc313ebe3af2ec338920d009ef514c9 293 SUPERFAMILY SSF48576 14 283 1.49E-81 T 28-03-2018 IPR008949 Isoprenoid synthase domain CPF12_RS09230 5dc313ebe3af2ec338920d009ef514c9 293 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CPF12_RS09230 5dc313ebe3af2ec338920d009ef514c9 293 Gene3D G3DSA:1.10.600.10 1 293 4.4E-78 T 28-03-2018 IPR008949 Isoprenoid synthase domain CPF12_RS01875 f022165fb1d4f7e0d4a5e00635e9453c 343 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 341 6.0E-139 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CPF12_RS01875 f022165fb1d4f7e0d4a5e00635e9453c 343 Pfam PF02547 Queuosine biosynthesis protein 4 341 5.6E-136 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CPF12_RS01875 f022165fb1d4f7e0d4a5e00635e9453c 343 Gene3D G3DSA:3.40.1780.10 1 135 3.0E-36 T 28-03-2018 CPF12_RS01875 f022165fb1d4f7e0d4a5e00635e9453c 343 Gene3D G3DSA:3.40.1780.10 173 342 2.6E-65 T 28-03-2018 CPF12_RS01875 f022165fb1d4f7e0d4a5e00635e9453c 343 SUPERFAMILY SSF111337 2 341 2.09E-136 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CPF12_RS01875 f022165fb1d4f7e0d4a5e00635e9453c 343 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 45.228 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 Pfam PF00367 phosphotransferase system, EIIB 477 508 4.5E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 487 504 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 3 549 5.5E-274 T 28-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 437 534 1.8E-15 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 Pfam PF02378 Phosphotransferase system, EIIC 14 376 2.8E-58 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 SUPERFAMILY SSF55604 474 549 4.18E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00920 5e84d2b7eab8d64b0a30535bba3044ca 550 Gene3D G3DSA:3.30.1360.60 472 548 3.6E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00370 a750d07365b7d9613320229cd079e596 105 Gene3D G3DSA:3.40.50.2300 4 102 4.9E-37 T 28-03-2018 CPF12_RS00370 a750d07365b7d9613320229cd079e596 105 SUPERFAMILY SSF52794 4 101 6.54E-33 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS00370 a750d07365b7d9613320229cd079e596 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 7 97 3.0E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS00370 a750d07365b7d9613320229cd079e596 105 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 6 90 8.2E-31 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 SMART SM00829 11 339 9.1E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 95 3.2E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 Pfam PF13602 Zinc-binding dehydrogenase 199 339 1.2E-16 T 28-03-2018 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 SUPERFAMILY SSF51735 122 280 6.5E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 8 341 2.2E-103 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 Gene3D G3DSA:3.90.180.10 3 164 4.6E-38 T 28-03-2018 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 Gene3D G3DSA:3.40.50.720 165 275 1.9E-13 T 28-03-2018 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 156 177 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CPF12_RS09130 973a4273f3182bb9bda544d5200f083b 347 SUPERFAMILY SSF50129 23 143 5.35E-29 T 28-03-2018 IPR011032 GroES-like CPF12_RS01045 03d524de43b571c04ae31997a20f59ae 410 Gene3D G3DSA:1.20.1250.20 205 408 2.6E-28 T 28-03-2018 CPF12_RS01045 03d524de43b571c04ae31997a20f59ae 410 SUPERFAMILY SSF103473 6 401 9.42E-82 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS01045 03d524de43b571c04ae31997a20f59ae 410 Gene3D G3DSA:1.20.1250.20 3 199 1.9E-40 T 28-03-2018 CPF12_RS01045 03d524de43b571c04ae31997a20f59ae 410 Pfam PF07690 Major Facilitator Superfamily 19 363 2.9E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 Gene3D G3DSA:3.50.50.60 8 155 9.1E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 1.0E-17 T 28-03-2018 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 1.0E-17 T 28-03-2018 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 1.0E-17 T 28-03-2018 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 1.0E-17 T 28-03-2018 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 Hamap MF_01685 Ferredoxin--NADP reductase. 13 336 43.388 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 1.6E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 283 301 1.6E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 1.6E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 15 37 1.6E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.6E-21 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 SUPERFAMILY SSF51905 14 323 5.98E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 299 9.8E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07055 55d1fe4a513a40d66576b5b15dbb03ff 339 Gene3D G3DSA:3.40.50.720 156 334 3.2E-18 T 28-03-2018 CPF12_RS10380 52ccc2ab0e27ece699daf6e7d903ab20 222 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS10380 52ccc2ab0e27ece699daf6e7d903ab20 222 Pfam PF00005 ABC transporter 26 170 1.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10380 52ccc2ab0e27ece699daf6e7d903ab20 222 Gene3D G3DSA:3.40.50.300 1 222 1.4E-58 T 28-03-2018 CPF12_RS10380 52ccc2ab0e27ece699daf6e7d903ab20 222 SUPERFAMILY SSF52540 3 221 1.1E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10380 52ccc2ab0e27ece699daf6e7d903ab20 222 SMART SM00382 32 221 1.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 Gene3D G3DSA:3.40.50.10490 5 242 1.6E-104 T 28-03-2018 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.9E-111 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 PRINTS PR00395 Ribosomal protein S2 signature 37 46 5.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 PRINTS PR00395 Ribosomal protein S2 signature 175 186 5.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 PRINTS PR00395 Ribosomal protein S2 signature 196 210 5.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 PRINTS PR00395 Ribosomal protein S2 signature 158 175 5.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 PRINTS PR00395 Ribosomal protein S2 signature 6 24 5.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 PRINTS PR00395 Ribosomal protein S2 signature 87 104 5.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 Pfam PF00318 Ribosomal protein S2 9 223 2.9E-101 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 SUPERFAMILY SSF52313 6 238 5.89E-100 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CPF12_RS12345 ca22046c80dedfdfe93474e1f79c1961 243 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.067 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Pfam PF01229 Glycosyl hydrolases family 39 336 821 1.8E-77 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 SMART SM00342 179 262 7.4E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Gene3D G3DSA:2.60.40.1500 672 823 6.3E-25 T 28-03-2018 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Gene3D G3DSA:3.20.20.80 341 671 1.2E-33 T 28-03-2018 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Pfam PF07883 Cupin domain 26 74 1.4E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 PRINTS PR00745 Glycosyl hydrolase family 39 signature 397 413 8.6E-16 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 PRINTS PR00745 Glycosyl hydrolase family 39 signature 610 627 8.6E-16 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 PRINTS PR00745 Glycosyl hydrolase family 39 signature 444 461 8.6E-16 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 PRINTS PR00745 Glycosyl hydrolase family 39 signature 461 477 8.6E-16 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 SUPERFAMILY SSF51011 672 823 1.94E-10 T 28-03-2018 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Gene3D G3DSA:1.10.10.60 217 279 6.7E-9 T 28-03-2018 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Gene3D G3DSA:1.10.10.60 152 216 1.9E-14 T 28-03-2018 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 ProSitePatterns PS01027 Glycosyl hydrolases family 39 active site. 464 473 - T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 SUPERFAMILY SSF51182 26 84 4.3E-11 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 SUPERFAMILY SSF46689 163 213 7.62E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Pfam PF12833 Helix-turn-helix domain 185 262 5.0E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 SUPERFAMILY SSF51445 336 680 1.39E-61 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 Gene3D G3DSA:2.60.120.10 2 130 1.7E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS05275 f57d3b94ed7aebe3c1ce3909142cd8ce 826 SUPERFAMILY SSF46689 215 263 4.93E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS10260 4ecf10cfab9e4365008e326d18707fd5 542 Pfam PF07693 KAP family P-loop domain 104 365 1.2E-25 T 28-03-2018 IPR011646 KAP family P-loop domain CPF12_RS10260 4ecf10cfab9e4365008e326d18707fd5 542 SUPERFAMILY SSF52540 97 204 3.1E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10260 4ecf10cfab9e4365008e326d18707fd5 542 SUPERFAMILY SSF52540 410 460 3.1E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10260 4ecf10cfab9e4365008e326d18707fd5 542 SUPERFAMILY SSF52540 280 352 3.1E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10260 4ecf10cfab9e4365008e326d18707fd5 542 Gene3D G3DSA:3.40.50.300 101 378 1.2E-11 T 28-03-2018 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 SUPERFAMILY SSF55120 1 245 2.16E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 Gene3D G3DSA:3.30.70.580 1 106 4.1E-30 T 28-03-2018 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 34.118 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 Pfam PF01416 tRNA pseudouridine synthase 144 245 8.1E-26 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 Pfam PF01416 tRNA pseudouridine synthase 8 105 2.3E-8 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 PIRSF PIRSF001430 1 246 1.3E-79 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 2.6E-58 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS04840 dc0dad02bef5cc80ecc1ea967b0ff218 246 Gene3D G3DSA:3.30.70.660 107 244 1.3E-39 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS03920 f90ab1291c81e18a5efaf9e174fc3035 554 Gene3D G3DSA:3.90.76.10 50 210 2.2E-39 T 28-03-2018 CPF12_RS03920 f90ab1291c81e18a5efaf9e174fc3035 554 SUPERFAMILY SSF53850 43 544 2.71E-113 T 28-03-2018 CPF12_RS03920 f90ab1291c81e18a5efaf9e174fc3035 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 472 8.7E-76 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CPF12_RS03920 f90ab1291c81e18a5efaf9e174fc3035 554 Gene3D G3DSA:3.10.105.10 310 525 1.3E-42 T 28-03-2018 CPF12_RS03920 f90ab1291c81e18a5efaf9e174fc3035 554 PIRSF PIRSF002741 3 554 1.1E-93 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CPF12_RS03920 f90ab1291c81e18a5efaf9e174fc3035 554 Gene3D G3DSA:3.40.190.10 211 309 7.1E-19 T 28-03-2018 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 Gene3D G3DSA:3.30.930.10 2 246 1.6E-68 T 28-03-2018 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 SUPERFAMILY SSF82649 245 331 7.85E-28 T 28-03-2018 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 SUPERFAMILY SSF55681 2 243 2.06E-78 T 28-03-2018 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 2.7E-119 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 246 330 1.1E-30 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 153 4.0E-11 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CPF12_RS02835 e144bc231e51adc8476349df3f68fb80 331 Gene3D G3DSA:3.30.390.50 247 331 8.9E-28 T 28-03-2018 CPF12_RS11220 f8c86b2c22e7b69d5aeeb84d625f94b8 207 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11220 f8c86b2c22e7b69d5aeeb84d625f94b8 207 Gene3D G3DSA:3.40.50.300 1 207 1.4E-58 T 28-03-2018 CPF12_RS11220 f8c86b2c22e7b69d5aeeb84d625f94b8 207 Pfam PF00005 ABC transporter 18 163 6.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11220 f8c86b2c22e7b69d5aeeb84d625f94b8 207 SMART SM00382 26 206 6.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11220 f8c86b2c22e7b69d5aeeb84d625f94b8 207 SUPERFAMILY SSF52540 2 205 1.11E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01295 f35bd45d544bc3818c451435e3ac3141 255 Pfam PF05709 Phage tail protein 53 240 9.0E-26 T 28-03-2018 IPR008841 Siphovirus-type tail component CPF12_RS01295 f35bd45d544bc3818c451435e3ac3141 255 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 23 147 1.0E-26 T 28-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal CPF12_RS08850 3b10acc00f06e54a5ad45f7584cb5af8 390 Gene3D G3DSA:3.40.50.2000 177 364 1.1E-34 T 28-03-2018 CPF12_RS08850 3b10acc00f06e54a5ad45f7584cb5af8 390 SUPERFAMILY SSF53756 73 374 9.81E-46 T 28-03-2018 CPF12_RS08850 3b10acc00f06e54a5ad45f7584cb5af8 390 Pfam PF00534 Glycosyl transferases group 1 205 357 3.0E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CPF12_RS07575 2360b651c0d86c546e2bebba24d342bc 248 PIRSF PIRSF017388 1 246 2.4E-78 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CPF12_RS07575 2360b651c0d86c546e2bebba24d342bc 248 Pfam PF12146 Serine aminopeptidase, S33 17 227 1.2E-13 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CPF12_RS07575 2360b651c0d86c546e2bebba24d342bc 248 SUPERFAMILY SSF53474 15 244 3.41E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS07575 2360b651c0d86c546e2bebba24d342bc 248 Gene3D G3DSA:3.40.50.1820 1 246 6.3E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS06455 43954da7c090fe9bf2433de9cd95f752 209 SUPERFAMILY SSF53271 4 207 2.23E-73 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS06455 43954da7c090fe9bf2433de9cd95f752 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.1E-90 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CPF12_RS06455 43954da7c090fe9bf2433de9cd95f752 209 Gene3D G3DSA:3.40.50.2020 2 207 1.8E-65 T 28-03-2018 CPF12_RS06455 43954da7c090fe9bf2433de9cd95f752 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.931 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CPF12_RS06455 43954da7c090fe9bf2433de9cd95f752 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 4.2E-75 T 28-03-2018 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 Gene3D G3DSA:3.40.50.620 1 188 2.0E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 326 41.197 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 3.9E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 3.9E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 3.9E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 3.9E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 SUPERFAMILY SSF52374 2 325 9.85E-97 T 28-03-2018 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 325 1.0E-116 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 Pfam PF00579 tRNA synthetases class I (W and Y) 3 279 6.0E-81 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS02685 c3413b6e2e8f8f9bd240747ba9a3e23a 328 Gene3D G3DSA:1.10.240.10 189 308 8.5E-35 T 28-03-2018 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 Gene3D G3DSA:3.40.190.10 152 307 9.0E-41 T 28-03-2018 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 4.7E-54 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 Gene3D G3DSA:3.40.190.10 24 151 3.7E-28 T 28-03-2018 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 Pfam PF13416 Bacterial extracellular solute-binding protein 50 320 9.5E-39 T 28-03-2018 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 PIRSF PIRSF019574 1 356 2.4E-126 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CPF12_RS08110 737bcc84b2436663a4fe8543fb69d6ec 357 SUPERFAMILY SSF53850 35 353 1.55E-92 T 28-03-2018 CPF12_RS00080 2bec2b9a4010ce28bcc947c6034d8a67 105 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 50 104 5.0E-16 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CPF12_RS00080 2bec2b9a4010ce28bcc947c6034d8a67 105 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 105 29.805 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CPF12_RS00080 2bec2b9a4010ce28bcc947c6034d8a67 105 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 27 101 3.6E-34 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CPF12_RS00080 2bec2b9a4010ce28bcc947c6034d8a67 105 SUPERFAMILY SSF141734 3 104 3.14E-44 T 28-03-2018 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 979 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Gene3D G3DSA:2.40.50.140 929 1027 3.4E-11 T 28-03-2018 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 269 689 5.9E-165 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Pfam PF02811 PHP domain 6 137 8.4E-26 T 28-03-2018 IPR004013 PHP domain GO:0003824 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Gene3D G3DSA:1.10.150.280 758 848 8.8E-6 T 28-03-2018 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Pfam PF01336 OB-fold nucleic acid binding domain 953 1019 3.9E-7 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Gene3D G3DSA:3.20.20.140 2 227 1.8E-19 T 28-03-2018 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 Pfam PF14579 Helix-hairpin-helix motif 764 851 5.4E-21 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 SMART SM00481 5 72 1.3E-12 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CPF12_RS08425 9f80b0c7002c5fbc98ec1b7087397262 1098 SUPERFAMILY SSF89550 18 76 1.39E-7 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CPF12_RS05230 cd953d72d0a2b94df35a2a488b5097ab 433 Pfam PF01610 Transposase 168 422 1.8E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS05230 cd953d72d0a2b94df35a2a488b5097ab 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS12300 cd953d72d0a2b94df35a2a488b5097ab 433 Pfam PF01610 Transposase 168 422 1.8E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS12300 cd953d72d0a2b94df35a2a488b5097ab 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS00385 486c2afefe2a0451a90819240d4113d3 145 SUPERFAMILY SSF55729 1 129 9.35E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS00385 486c2afefe2a0451a90819240d4113d3 145 Pfam PF13673 Acetyltransferase (GNAT) domain 38 132 6.5E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS00385 486c2afefe2a0451a90819240d4113d3 145 Gene3D G3DSA:3.40.630.30 1 145 2.7E-17 T 28-03-2018 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.0E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 Gene3D G3DSA:3.40.50.2300 156 321 2.5E-30 T 28-03-2018 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 SUPERFAMILY SSF53822 58 306 4.07E-42 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 Gene3D G3DSA:1.10.260.40 2 57 8.6E-21 T 28-03-2018 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 Gene3D G3DSA:3.40.50.2300 58 155 5.3E-18 T 28-03-2018 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 Pfam PF13377 Periplasmic binding protein-like domain 176 317 5.9E-18 T 28-03-2018 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 SUPERFAMILY SSF47413 1 59 8.75E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS02455 c95b86181fdb8e82ff41ee6a60ed73ab 322 SMART SM00354 1 71 2.9E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 SMART SM00411 2 91 1.9E-49 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 Gene3D G3DSA:4.10.520.10 1 91 1.6E-37 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 1.7E-36 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 8.5E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 8.5E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 8.5E-22 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CPF12_RS09485 4701bdc15b2230f57487e182d575ab2e 91 SUPERFAMILY SSF47729 3 91 1.47E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 Gene3D G3DSA:2.60.120.10 74 179 6.1E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 Pfam PF07883 Cupin domain 124 171 2.0E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 Pfam PF01381 Helix-turn-helix 7 59 2.5E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 SUPERFAMILY SSF51182 54 176 4.61E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 SMART SM00530 6 61 2.2E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 SUPERFAMILY SSF47413 1 64 2.45E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS08090 9ab2b8e7162e6a50179328718a6cae20 180 Gene3D G3DSA:1.10.260.40 1 73 3.3E-21 T 28-03-2018 CPF12_RS05980 e56c591ddedcede667b54f97c5e3b745 49 SUPERFAMILY SSF57829 3 49 1.34E-13 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CPF12_RS05980 e56c591ddedcede667b54f97c5e3b745 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 14.798 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05980 e56c591ddedcede667b54f97c5e3b745 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 4 49 5.6E-11 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05980 e56c591ddedcede667b54f97c5e3b745 49 Pfam PF00471 Ribosomal protein L33 4 49 3.7E-15 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS00115 14d7ee2c6676cb2fcc1515ad4a08cdda 394 PIRSF PIRSF001549 2 390 2.5E-64 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CPF12_RS00115 14d7ee2c6676cb2fcc1515ad4a08cdda 394 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 319 3.8E-86 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CPF12_RS00115 14d7ee2c6676cb2fcc1515ad4a08cdda 394 Pfam PF13393 Histidyl-tRNA synthetase 10 314 8.2E-72 T 28-03-2018 CPF12_RS00115 14d7ee2c6676cb2fcc1515ad4a08cdda 394 Gene3D G3DSA:3.30.930.10 4 328 1.2E-53 T 28-03-2018 CPF12_RS00115 14d7ee2c6676cb2fcc1515ad4a08cdda 394 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 17 366 28.935 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CPF12_RS00115 14d7ee2c6676cb2fcc1515ad4a08cdda 394 SUPERFAMILY SSF55681 5 321 2.7E-53 T 28-03-2018 CPF12_RS02830 f797b4755937cdc08acfc74eac1791d3 178 Pfam PF00881 Nitroreductase family 10 154 2.3E-16 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CPF12_RS02830 f797b4755937cdc08acfc74eac1791d3 178 SUPERFAMILY SSF55469 3 166 1.26E-28 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CPF12_RS02830 f797b4755937cdc08acfc74eac1791d3 178 Gene3D G3DSA:3.40.109.10 1 178 2.4E-27 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CPF12_RS11500 73d0c623582ceaeda3801a84f258a1c5 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 3.6E-30 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CPF12_RS06155 0f0065c5a011374d79e08e4eb0d7a4d9 146 SUPERFAMILY SSF52080 4 144 1.13E-49 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CPF12_RS06155 0f0065c5a011374d79e08e4eb0d7a4d9 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 4.6E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CPF12_RS06155 0f0065c5a011374d79e08e4eb0d7a4d9 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 7.2E-56 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06155 0f0065c5a011374d79e08e4eb0d7a4d9 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06155 0f0065c5a011374d79e08e4eb0d7a4d9 146 Gene3D G3DSA:3.100.10.10 41 146 4.2E-33 T 28-03-2018 CPF12_RS06155 0f0065c5a011374d79e08e4eb0d7a4d9 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.348 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CPF12_RS09600 71b52586ab9a738fdbdcec52ab375f71 139 SUPERFAMILY SSF46785 2 125 1.77E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09600 71b52586ab9a738fdbdcec52ab375f71 139 Gene3D G3DSA:1.10.10.10 1 139 2.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09600 71b52586ab9a738fdbdcec52ab375f71 139 Pfam PF02082 Transcriptional regulator 1 82 1.6E-26 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS09600 71b52586ab9a738fdbdcec52ab375f71 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 1.1E-34 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS09600 71b52586ab9a738fdbdcec52ab375f71 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 Gene3D G3DSA:3.40.50.300 1 169 2.5E-26 T 28-03-2018 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 ProSitePatterns PS01128 Shikimate kinase signature. 61 87 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 SUPERFAMILY SSF52540 6 166 3.44E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 Pfam PF01202 Shikimate kinase 14 168 4.5E-39 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 PRINTS PR01100 Shikimate kinase family signature 60 68 1.5E-17 T 28-03-2018 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 PRINTS PR01100 Shikimate kinase family signature 79 88 1.5E-17 T 28-03-2018 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 PRINTS PR01100 Shikimate kinase family signature 32 45 1.5E-17 T 28-03-2018 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 PRINTS PR01100 Shikimate kinase family signature 8 23 1.5E-17 T 28-03-2018 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 PRINTS PR01100 Shikimate kinase family signature 100 117 1.5E-17 T 28-03-2018 CPF12_RS02585 24ad9a39d4811049172091c083d2da9e 169 Hamap MF_00109 Shikimate kinase [aroK]. 5 167 24.414 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 4.6E-29 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 131 22.818 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 Gene3D G3DSA:2.60.15.10 1 89 4.2E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 4.0E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 SUPERFAMILY SSF51344 3 83 4.05E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 SUPERFAMILY SSF46604 87 132 2.01E-5 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 132 1.8E-14 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 Gene3D G3DSA:1.20.5.440 91 133 1.2E-13 T 28-03-2018 CPF12_RS06500 0562b279762d4d36d44eb3447412359c 135 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 132 1.4E-33 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS01770 54588fed871a16ff1f3fb3b54a100aa2 192 Pfam PF04892 VanZ like family 49 182 6.3E-9 T 28-03-2018 IPR006976 VanZ-like CPF12_RS02225 da5cf91604f5b4aed899a216c63b0ec3 549 Gene3D G3DSA:3.40.190.10 177 311 2.8E-33 T 28-03-2018 CPF12_RS02225 da5cf91604f5b4aed899a216c63b0ec3 549 SUPERFAMILY SSF53850 38 545 2.32E-107 T 28-03-2018 CPF12_RS02225 da5cf91604f5b4aed899a216c63b0ec3 549 Gene3D G3DSA:3.90.76.10 29 176 1.4E-28 T 28-03-2018 CPF12_RS02225 da5cf91604f5b4aed899a216c63b0ec3 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 468 4.7E-73 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CPF12_RS02225 da5cf91604f5b4aed899a216c63b0ec3 549 PIRSF PIRSF002741 1 549 1.8E-94 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CPF12_RS02225 da5cf91604f5b4aed899a216c63b0ec3 549 Gene3D G3DSA:3.10.105.10 312 520 3.9E-41 T 28-03-2018 CPF12_RS01980 fe4d03deb6efc3e5885a2f54184f33fc 257 SUPERFAMILY SSF55174 179 251 1.96E-31 T 28-03-2018 CPF12_RS01980 fe4d03deb6efc3e5885a2f54184f33fc 257 SUPERFAMILY SSF55174 36 127 1.96E-31 T 28-03-2018 CPF12_RS01980 fe4d03deb6efc3e5885a2f54184f33fc 257 SMART SM00363 182 244 1.9E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS01980 fe4d03deb6efc3e5885a2f54184f33fc 257 Gene3D G3DSA:3.10.290.10 181 251 5.9E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS01980 fe4d03deb6efc3e5885a2f54184f33fc 257 Pfam PF01479 S4 domain 182 227 3.5E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 Gene3D G3DSA:3.40.50.300 77 252 2.0E-19 T 28-03-2018 CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 Gene3D G3DSA:3.40.50.300 287 431 6.4E-23 T 28-03-2018 CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 SMART SM00487 89 263 5.1E-10 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 SUPERFAMILY SSF52540 106 406 6.62E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 SMART SM00490 314 396 2.9E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 Pfam PF04851 Type III restriction enzyme, res subunit 95 190 4.5E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CPF12_RS06630 7e6dfff9b46c0c46b082fead5bcdf765 432 Pfam PF00271 Helicase conserved C-terminal domain 290 395 8.0E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Gene3D G3DSA:3.40.50.300 554 768 7.1E-54 T 28-03-2018 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 1.2E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 1.2E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 1.2E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 1.2E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 SMART SM00382 197 342 1.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 SMART SM00382 599 751 3.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 99 143 0.15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 7.1E-7 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 763 1.5E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 SUPERFAMILY SSF52540 156 547 1.88E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 SUPERFAMILY SSF52540 548 856 4.91E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 335 4.2E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Gene3D G3DSA:1.10.8.60 342 549 7.0E-45 T 28-03-2018 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 849 2.5E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Gene3D G3DSA:1.10.1780.10 1 149 9.4E-19 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Gene3D G3DSA:3.40.50.300 156 341 4.7E-26 T 28-03-2018 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 SMART SM01086 769 858 2.0E-31 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 Gene3D G3DSA:1.10.8.60 769 862 4.0E-22 T 28-03-2018 CPF12_RS02740 c027d9b472ec7197869165b14088f885 862 SUPERFAMILY SSF81923 4 154 5.49E-30 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 PIRSF PIRSF002741 1 521 2.5E-109 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 SUPERFAMILY SSF53850 38 508 2.17E-115 T 28-03-2018 CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 Gene3D G3DSA:3.10.105.10 287 493 7.9E-45 T 28-03-2018 CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 107 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 Gene3D G3DSA:3.40.190.10 193 286 1.8E-27 T 28-03-2018 CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 Gene3D G3DSA:3.90.76.10 49 192 2.3E-30 T 28-03-2018 CPF12_RS10910 6c0a8dac995664345ba83d8a027d0693 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 438 3.8E-88 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 8 171 3.7E-59 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 Gene3D G3DSA:3.40.1710.10 45 223 1.2E-25 T 28-03-2018 CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 723 928 1.1E-66 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 237 264 6.9E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 244 271 6.3E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 622 649 6.0E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 671 698 3.6E-8 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 286 313 2.0E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 315 341 6.2E-9 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 219 243 2.9E-4 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 643 670 1.5E-9 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 573 600 1.2E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 Gene3D G3DSA:1.20.120.570 430 608 1.6E-13 T 28-03-2018 CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 Gene3D G3DSA:1.20.120.570 229 366 2.6E-21 T 28-03-2018 CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 Gene3D G3DSA:1.20.120.570 609 724 5.9E-15 T 28-03-2018 CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 Pfam PF12698 ABC-2 family transporter protein 717 921 1.1E-13 T 28-03-2018 CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 Pfam PF12698 ABC-2 family transporter protein 22 175 5.3E-14 T 28-03-2018 CPF12_RS09945 116a76dd51786822e65ce349bea4873b 939 SUPERFAMILY SSF101967 191 357 7.72E-6 T 28-03-2018 CPF12_RS09155 2329d111d991187118a10e9df5e8a072 130 SUPERFAMILY SSF55331 2 128 2.79E-30 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CPF12_RS09155 2329d111d991187118a10e9df5e8a072 130 Gene3D G3DSA:3.30.429.10 2 124 1.4E-23 T 28-03-2018 CPF12_RS09155 2329d111d991187118a10e9df5e8a072 130 Pfam PF14552 Tautomerase enzyme 38 121 2.5E-20 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CPF12_RS11340 82854698207a295a4d579d662489bff0 254 SUPERFAMILY SSF63380 3 97 1.34E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CPF12_RS11340 82854698207a295a4d579d662489bff0 254 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 3 254 35.645 T 28-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CPF12_RS11340 82854698207a295a4d579d662489bff0 254 SUPERFAMILY SSF52343 92 252 6.94E-32 T 28-03-2018 CPF12_RS11340 82854698207a295a4d579d662489bff0 254 Pfam PF00175 Oxidoreductase NAD-binding domain 110 198 4.5E-5 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CPF12_RS11340 82854698207a295a4d579d662489bff0 254 Gene3D G3DSA:2.10.240.10 212 253 2.7E-16 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CPF12_RS11340 82854698207a295a4d579d662489bff0 254 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 212 252 4.9E-17 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CPF12_RS11340 82854698207a295a4d579d662489bff0 254 Gene3D G3DSA:3.40.50.80 99 207 1.9E-12 T 28-03-2018 CPF12_RS11340 82854698207a295a4d579d662489bff0 254 PIRSF PIRSF006816 1 254 7.6E-68 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CPF12_RS11340 82854698207a295a4d579d662489bff0 254 Gene3D G3DSA:2.40.30.10 2 95 4.8E-13 T 28-03-2018 CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 Gene3D G3DSA:3.40.1360.10 77 170 3.3E-39 T 28-03-2018 CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 SMART SM00493 80 165 4.2E-18 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 2.8E-88 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 111.377 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 Pfam PF13662 Toprim domain 81 171 6.8E-25 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 Pfam PF02132 RecR protein 39 78 3.9E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CPF12_RS05650 1d3013d9710ccc82abb5e39a0e3b90e9 198 SUPERFAMILY SSF111304 1 198 2.88E-78 T 28-03-2018 IPR023627 Recombination protein RecR CPF12_RS09115 3d0f64f3d574003e4672dd2c083a8074 114 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 110 9.5E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CPF12_RS09115 3d0f64f3d574003e4672dd2c083a8074 114 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 113 15.537 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 Gene3D G3DSA:2.40.50.140 1 78 3.5E-27 T 28-03-2018 CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 438 448 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 Gene3D G3DSA:3.40.50.150 79 454 1.7E-63 T 28-03-2018 CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 SUPERFAMILY SSF53335 71 451 4.62E-93 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 448 4.0E-167 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 268 449 2.8E-16 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 386 417 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 SUPERFAMILY SSF50249 4 63 1.88E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS09925 a9b439c7280c6426bf2e3485b9ce971a 457 Pfam PF01938 TRAM domain 9 62 8.1E-12 T 28-03-2018 IPR002792 TRAM domain CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 ProSitePatterns PS01087 Radical activating enzymes signature. 20 41 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 8 243 7.1E-103 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 PIRSF PIRSF000371 1 49 2.5E-13 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 PIRSF PIRSF000371 47 247 4.1E-42 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 SUPERFAMILY SSF102114 25 226 9.81E-25 T 28-03-2018 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 Pfam PF13353 4Fe-4S single cluster domain 18 146 9.7E-19 T 28-03-2018 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 Gene3D G3DSA:3.80.30.10 70 249 8.3E-35 T 28-03-2018 CPF12_RS04195 cb2f62a9e04922b38eb8385401fb7628 249 Pfam PF04055 Radical SAM superfamily 26 187 5.0E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CPF12_RS10580 d83a28bd3a334bca00b442daf4e047fe 277 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 272 2.6E-66 T 28-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CPF12_RS10580 d83a28bd3a334bca00b442daf4e047fe 277 Pfam PF13263 PHP-associated 244 272 7.8E-7 T 28-03-2018 CPF12_RS10580 d83a28bd3a334bca00b442daf4e047fe 277 SUPERFAMILY SSF89550 160 276 4.84E-32 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CPF12_RS10580 d83a28bd3a334bca00b442daf4e047fe 277 SUPERFAMILY SSF89550 1 131 4.84E-32 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CPF12_RS10580 d83a28bd3a334bca00b442daf4e047fe 277 Pfam PF02811 PHP domain 5 184 7.8E-10 T 28-03-2018 IPR004013 PHP domain GO:0003824 CPF12_RS10580 d83a28bd3a334bca00b442daf4e047fe 277 Gene3D G3DSA:3.20.20.140 1 277 1.9E-33 T 28-03-2018 CPF12_RS00260 00dabf10aa34c509a9e52f8e83a709e1 220 SUPERFAMILY SSF109604 14 219 3.35E-67 T 28-03-2018 CPF12_RS00260 00dabf10aa34c509a9e52f8e83a709e1 220 Pfam PF12261 Thermostable hemolysin 167 211 2.5E-4 T 28-03-2018 IPR022050 Thermostable hemolysin CPF12_RS00260 00dabf10aa34c509a9e52f8e83a709e1 220 Gene3D G3DSA:1.10.3210.10 12 220 4.0E-20 T 28-03-2018 CPF12_RS00260 00dabf10aa34c509a9e52f8e83a709e1 220 Pfam PF01966 HD domain 33 131 3.2E-6 T 28-03-2018 IPR006674 HD domain CPF12_RS00260 00dabf10aa34c509a9e52f8e83a709e1 220 SMART SM00471 26 141 6.2E-5 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 Gene3D G3DSA:3.40.50.300 1 282 1.9E-49 T 28-03-2018 CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 Gene3D G3DSA:3.40.50.300 293 556 5.4E-49 T 28-03-2018 CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 Pfam PF00005 ABC transporter 347 475 5.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 Pfam PF00005 ABC transporter 19 189 4.0E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 SMART SM00382 355 520 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 SMART SM00382 27 241 1.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 SUPERFAMILY SSF52540 130 271 3.29E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 SUPERFAMILY SSF52540 2 93 3.29E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 Pfam PF12848 ABC transporter 228 319 1.2E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain CPF12_RS10400 7e9997f497c162b7338eb53cd18f1173 614 SUPERFAMILY SSF52540 323 534 1.27E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 352 3.4E-112 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 SUPERFAMILY SSF56796 5 354 5.76E-96 T 28-03-2018 CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 PIRSF PIRSF001455 3 359 6.4E-104 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 Gene3D G3DSA:3.40.50.1970 2 173 1.6E-44 T 28-03-2018 CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 Gene3D G3DSA:1.20.1090.10 174 359 1.0E-52 T 28-03-2018 CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 357 37.264 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CPF12_RS09525 2cdbd47d19bde81bd27f71b539117ba4 359 Pfam PF01761 3-dehydroquinate synthase 69 325 1.7E-92 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 ProSitePatterns PS00855 Signal peptidases II signature. 93 105 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 46 54 2.9E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 90 105 2.9E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 2.9E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 TIGRFAM TIGR00077 lspA: signal peptidase II 4 149 2.3E-37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 151 16.189 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS11300 c54b46e37d57017ee58af04d92e82b35 164 Pfam PF01252 Signal peptidase (SPase) II 8 146 2.8E-36 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 SUPERFAMILY SSF51905 3 307 2.43E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 306 1.2E-117 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 6.6E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 Gene3D G3DSA:3.50.50.60 129 239 4.7E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 3.6E-36 T 28-03-2018 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 3.6E-36 T 28-03-2018 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.6E-36 T 28-03-2018 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.6E-36 T 28-03-2018 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.6E-36 T 28-03-2018 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 Gene3D G3DSA:3.50.50.60 1 128 5.0E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 Gene3D G3DSA:3.50.50.60 240 318 1.3E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 2.0E-73 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS06790 8647383f04f02c8269d7f83755c99710 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CPF12_RS09335 fcd631ce93729655606c1ac02ab7b102 336 SMART SM00322 6 70 0.0013 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CPF12_RS09335 fcd631ce93729655606c1ac02ab7b102 336 Pfam PF02562 PhoH-like protein 115 317 7.8E-92 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CPF12_RS09335 fcd631ce93729655606c1ac02ab7b102 336 Gene3D G3DSA:3.30.1370.10 1 96 6.4E-8 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS09335 fcd631ce93729655606c1ac02ab7b102 336 SUPERFAMILY SSF54791 15 69 2.19E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CPF12_RS09335 fcd631ce93729655606c1ac02ab7b102 336 SUPERFAMILY SSF52540 114 282 7.36E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09335 fcd631ce93729655606c1ac02ab7b102 336 Gene3D G3DSA:3.40.50.300 112 310 1.1E-27 T 28-03-2018 CPF12_RS12365 a103ed8278499aad242b31fba393dc66 194 SUPERFAMILY SSF55729 3 184 3.72E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS12365 a103ed8278499aad242b31fba393dc66 194 Pfam PF00583 Acetyltransferase (GNAT) family 56 168 7.0E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS12365 a103ed8278499aad242b31fba393dc66 194 Gene3D G3DSA:3.40.630.30 1 187 1.5E-25 T 28-03-2018 CPF12_RS08230 ff6122a3d91b8e0650e96ce1756ef3bc 382 SUPERFAMILY SSF56349 69 374 2.69E-62 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS08230 ff6122a3d91b8e0650e96ce1756ef3bc 382 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 70 123 1.5E-19 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CPF12_RS08230 ff6122a3d91b8e0650e96ce1756ef3bc 382 Pfam PF14657 Arm DNA-binding domain 14 59 7.4E-12 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CPF12_RS08230 ff6122a3d91b8e0650e96ce1756ef3bc 382 Gene3D G3DSA:1.10.150.130 62 170 7.5E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CPF12_RS08230 ff6122a3d91b8e0650e96ce1756ef3bc 382 Gene3D G3DSA:1.10.443.10 172 381 9.2E-40 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS08230 ff6122a3d91b8e0650e96ce1756ef3bc 382 Pfam PF00589 Phage integrase family 179 366 1.3E-28 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 Gene3D G3DSA:3.40.50.300 325 577 9.2E-68 T 28-03-2018 CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 Pfam PF00664 ABC transporter transmembrane region 19 291 2.0E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 SUPERFAMILY SSF52540 330 572 2.61E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 Gene3D G3DSA:1.20.1560.10 1 324 1.4E-61 T 28-03-2018 CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 SUPERFAMILY SSF90123 5 315 6.02E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 SMART SM00382 361 547 3.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12415 03e95919abdf75c36fa7086a262a75f2 582 Pfam PF00005 ABC transporter 352 500 2.7E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS05585 8ab3b6b71a25659576b2ed3885b7f78c 190 Gene3D G3DSA:3.40.50.1240 1 188 8.1E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS05585 8ab3b6b71a25659576b2ed3885b7f78c 190 PIRSF PIRSF000709 2 145 1.3E-13 T 28-03-2018 CPF12_RS05585 8ab3b6b71a25659576b2ed3885b7f78c 190 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 179 1.7E-39 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS05585 8ab3b6b71a25659576b2ed3885b7f78c 190 SUPERFAMILY SSF53254 1 185 8.95E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 Gene3D G3DSA:3.20.20.80 2 476 1.1E-148 T 28-03-2018 CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 SUPERFAMILY SSF51445 2 472 2.34E-159 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 1.6E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 1.6E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 437 449 1.6E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 1.6E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 1.6E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04345 2569475f23e3b3592a5c7ec6efb7247a 483 Pfam PF00232 Glycosyl hydrolase family 1 4 472 1.2E-131 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS09275 56bd0645403745828011adca3b73d598 379 Pfam PF06969 HemN C-terminal domain 304 366 6.9E-14 T 28-03-2018 IPR010723 HemN, C-terminal CPF12_RS09275 56bd0645403745828011adca3b73d598 379 Gene3D G3DSA:3.20.20.70 2 311 6.5E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS09275 56bd0645403745828011adca3b73d598 379 Pfam PF04055 Radical SAM superfamily 6 176 1.8E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CPF12_RS09275 56bd0645403745828011adca3b73d598 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 3 366 1.2E-120 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CPF12_RS09275 56bd0645403745828011adca3b73d598 379 SMART SM00729 1 222 1.3E-59 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CPF12_RS09275 56bd0645403745828011adca3b73d598 379 SUPERFAMILY SSF102114 3 376 1.16E-120 T 28-03-2018 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 SUPERFAMILY SSF103473 462 491 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 SUPERFAMILY SSF103473 8 198 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 SUPERFAMILY SSF103473 251 422 2.22E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 Gene3D G3DSA:1.20.1250.20 7 204 7.3E-31 T 28-03-2018 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 484 4.8E-127 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 Gene3D G3DSA:1.20.1250.20 262 495 4.1E-31 T 28-03-2018 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 Pfam PF07690 Major Facilitator Superfamily 21 412 1.6E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 7.4E-11 T 28-03-2018 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 305 329 7.4E-11 T 28-03-2018 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 7.4E-11 T 28-03-2018 CPF12_RS10795 29c0bb3c2ff8acfd10732a028fe8e815 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 7.4E-11 T 28-03-2018 CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 29.535 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 PIRSF PIRSF005485 1 340 2.6E-104 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 Pfam PF01628 HrcA protein C terminal domain 105 322 5.9E-56 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 SUPERFAMILY SSF46785 1 81 6.54E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 Gene3D G3DSA:1.10.10.10 1 83 2.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 SUPERFAMILY SSF55781 71 338 1.94E-59 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 Gene3D G3DSA:3.30.450.40 184 342 1.2E-37 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS09280 6e15bbfcd819a86872a26c4df32dbb90 348 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 2.7E-98 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 SMART SM00862 145 219 4.2E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 9.4E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 Gene3D G3DSA:3.40.50.2300 1 125 4.7E-36 T 28-03-2018 CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 SUPERFAMILY SSF52172 3 169 2.99E-41 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 Pfam PF00072 Response regulator receiver domain 4 112 8.9E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 Gene3D G3DSA:1.10.10.10 126 223 7.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08545 c58419c1a4977df4ab1612d7f4feea7d 223 SMART SM00448 2 112 8.0E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS02760 54646f9be53331dc5ac778ce8fcd6152 220 Gene3D G3DSA:1.20.5.170 134 219 2.9E-8 T 28-03-2018 CPF12_RS02760 54646f9be53331dc5ac778ce8fcd6152 220 SUPERFAMILY SSF58100 82 217 9.15E-8 T 28-03-2018 CPF12_RS02760 54646f9be53331dc5ac778ce8fcd6152 220 Gene3D G3DSA:1.20.120.330 35 133 2.4E-8 T 28-03-2018 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Gene3D G3DSA:3.30.1490.100 246 356 3.6E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Pfam PF11799 impB/mucB/samB family C-terminal domain 239 346 1.5E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Gene3D G3DSA:1.10.150.20 176 245 8.3E-18 T 28-03-2018 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 SUPERFAMILY SSF100879 243 342 5.34E-24 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Pfam PF11798 IMS family HHH motif 171 202 2.6E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Gene3D G3DSA:3.30.70.270 46 119 3.9E-24 T 28-03-2018 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Gene3D G3DSA:3.30.70.270 120 175 4.5E-17 T 28-03-2018 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 SUPERFAMILY SSF56672 3 239 2.05E-90 T 28-03-2018 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Pfam PF00817 impB/mucB/samB family 10 159 1.4E-52 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS11075 c2303731066c09a6a521c67bd596d404 357 Hamap MF_01113 DNA polymerase IV [dinB]. 4 354 38.36 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 9.5E-39 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 Pfam PF00312 Ribosomal protein S15 8 88 6.1E-37 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 SMART SM01387 8 88 7.5E-52 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 2.0E-23 T 28-03-2018 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 Gene3D G3DSA:1.10.287.10 2 89 5.1E-36 T 28-03-2018 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.377 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS12160 4ea940e2aa0dc0fb162993b6dd796cc5 89 SUPERFAMILY SSF47060 3 89 2.65E-35 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CPF12_RS02625 cb5de63ecfe0fb51337a645ce779fcb8 193 Gene3D G3DSA:2.40.320.10 1 178 7.8E-35 T 28-03-2018 CPF12_RS02625 cb5de63ecfe0fb51337a645ce779fcb8 193 SMART SM01118 3 192 2.0E-20 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CPF12_RS02625 cb5de63ecfe0fb51337a645ce779fcb8 193 Pfam PF01928 CYTH domain 4 186 3.7E-28 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CPF12_RS02625 cb5de63ecfe0fb51337a645ce779fcb8 193 PIRSF PIRSF012526 1 193 5.1E-66 T 28-03-2018 IPR009195 Uncharacterised protein family YjbK CPF12_RS02625 cb5de63ecfe0fb51337a645ce779fcb8 193 SUPERFAMILY SSF55154 4 187 2.45E-27 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CPF12_RS00165 048872f7d212b504cd462c4a4e060ce3 89 SUPERFAMILY SSF159133 1 88 7.46E-29 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CPF12_RS00165 048872f7d212b504cd462c4a4e060ce3 89 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 12 83 2.0E-11 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CPF12_RS00165 048872f7d212b504cd462c4a4e060ce3 89 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 83 5.7E-29 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CPF12_RS00165 048872f7d212b504cd462c4a4e060ce3 89 Gene3D G3DSA:2.40.50.220 1 89 4.7E-31 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 SUPERFAMILY SSF55945 61 123 2.2E-5 T 28-03-2018 CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 56 123 3.2E-6 T 28-03-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 Gene3D G3DSA:3.30.310.20 7 127 7.0E-16 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 Gene3D G3DSA:1.10.1670.10 251 302 3.3E-12 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 Gene3D G3DSA:1.10.340.30 128 249 5.3E-19 T 28-03-2018 CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 SUPERFAMILY SSF48150 116 301 2.04E-37 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 136 287 7.5E-12 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS11985 63b6b86f9578ae169454f046874cd6c3 302 SMART SM00478 137 302 5.9E-16 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CPF12_RS06985 6197ea3e9cda761f12d8856c22993ce9 189 SUPERFAMILY SSF89360 8 102 3.14E-17 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS06985 6197ea3e9cda761f12d8856c22993ce9 189 Gene3D G3DSA:2.60.300.12 7 114 5.1E-20 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS06985 6197ea3e9cda761f12d8856c22993ce9 189 Pfam PF01521 Iron-sulphur cluster biosynthesis 8 104 3.3E-7 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS02650 a1ab99146ace96cd03f8da142bd3386a 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02650 a1ab99146ace96cd03f8da142bd3386a 242 PIRSF PIRSF039085 1 242 3.1E-118 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CPF12_RS02650 a1ab99146ace96cd03f8da142bd3386a 242 Pfam PF00005 ABC transporter 19 167 3.2E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02650 a1ab99146ace96cd03f8da142bd3386a 242 Gene3D G3DSA:3.40.50.300 1 241 8.4E-80 T 28-03-2018 CPF12_RS02650 a1ab99146ace96cd03f8da142bd3386a 242 SUPERFAMILY SSF52540 4 237 1.52E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02650 a1ab99146ace96cd03f8da142bd3386a 242 SMART SM00382 28 223 2.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 SUPERFAMILY SSF52540 38 263 1.6E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 Pfam PF00005 ABC transporter 44 191 8.3E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 Gene3D G3DSA:3.40.50.300 2 272 5.6E-75 T 28-03-2018 CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 35 390 4.8E-139 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 Pfam PF00571 CBS domain 337 388 0.0028 T 28-03-2018 IPR000644 CBS domain CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 Gene3D G3DSA:3.10.580.10 273 394 9.9E-14 T 28-03-2018 CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 SMART SM00382 52 241 1.5E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03860 1267c32c03a9ebe83fc14eb2caf476df 394 SUPERFAMILY SSF54631 273 389 1.77E-12 T 28-03-2018 CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 Pfam PF00486 Transcriptional regulatory protein, C terminal 136 212 3.7E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 Gene3D G3DSA:1.10.10.10 111 216 5.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 SMART SM00448 1 94 1.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 Gene3D G3DSA:3.40.50.2300 1 110 1.9E-31 T 28-03-2018 CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 SMART SM00862 135 212 2.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 Pfam PF00072 Response regulator receiver domain 2 94 1.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS09415 d3cc5e9f52cba7ec9c44f8a1f4400cb7 216 SUPERFAMILY SSF52172 2 170 3.44E-34 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS10935 b74e0ae88c39099936c3d6aa3fa9de29 230 Gene3D G3DSA:3.40.30.10 1 212 3.5E-54 T 28-03-2018 CPF12_RS10935 b74e0ae88c39099936c3d6aa3fa9de29 230 Pfam PF01323 DSBA-like thioredoxin domain 2 201 2.4E-48 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CPF12_RS10935 b74e0ae88c39099936c3d6aa3fa9de29 230 SUPERFAMILY SSF52833 1 207 1.49E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Gene3D G3DSA:1.10.10.10 51 115 2.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Gene3D G3DSA:1.10.10.10 223 270 5.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Gene3D G3DSA:1.10.10.10 166 215 0.064 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Hamap MF_01114 Regulatory protein RecX [recX]. 50 271 14.805 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Pfam PF02631 RecX family 204 268 1.2E-5 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Pfam PF02631 RecX family 92 203 1.0E-24 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CPF12_RS09965 813434000084ec0dbe24f76df95408aa 272 Gene3D G3DSA:1.10.10.10 116 160 2.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05935 0064e67baa1ecfbbd5053635046ce1c7 232 Gene3D G3DSA:3.90.550.10 1 231 2.3E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS05935 0064e67baa1ecfbbd5053635046ce1c7 232 SUPERFAMILY SSF53448 4 226 5.41E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS05935 0064e67baa1ecfbbd5053635046ce1c7 232 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 224 3.0E-70 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CPF12_RS05935 0064e67baa1ecfbbd5053635046ce1c7 232 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 226 2.5E-73 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CPF12_RS05935 0064e67baa1ecfbbd5053635046ce1c7 232 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 103 110 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CPF12_RS05935 0064e67baa1ecfbbd5053635046ce1c7 232 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 3 225 39.81 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 587 603 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Gene3D G3DSA:3.40.930.10 536 683 3.3E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 SUPERFAMILY SSF55804 537 682 1.44E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Gene3D G3DSA:1.10.1790.10 287 391 8.0E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 540 682 3.0E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Pfam PF05043 Mga helix-turn-helix domain 92 160 1.9E-4 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 SUPERFAMILY SSF52794 403 480 8.89E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Gene3D G3DSA:1.10.10.10 1 68 0.33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Gene3D G3DSA:1.10.10.10 86 151 2.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Pfam PF00874 PRD domain 298 386 1.7E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 Gene3D G3DSA:3.40.50.2300 397 485 1.1E-14 T 28-03-2018 CPF12_RS10725 542777bd4ff0e0775af83c23c2b42adc 685 SUPERFAMILY SSF63520 268 388 3.75E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS06380 59ad7ba993dcf59a681f6de868959399 436 Pfam PF01966 HD domain 58 181 3.1E-12 T 28-03-2018 IPR006674 HD domain CPF12_RS06380 59ad7ba993dcf59a681f6de868959399 436 SMART SM00471 54 188 7.3E-13 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS06380 59ad7ba993dcf59a681f6de868959399 436 SUPERFAMILY SSF109604 3 419 2.22E-114 T 28-03-2018 CPF12_RS06380 59ad7ba993dcf59a681f6de868959399 436 Gene3D G3DSA:1.10.3210.10 7 313 2.2E-72 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 SUPERFAMILY SSF161098 511 699 5.49E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 SUPERFAMILY SSF53850 267 491 2.42E-64 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Gene3D G3DSA:1.10.3720.10 506 716 3.6E-44 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Gene3D G3DSA:3.40.190.10 259 369 2.0E-34 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Gene3D G3DSA:3.40.190.10 25 133 3.3E-32 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 SUPERFAMILY SSF53850 1 254 2.33E-64 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 SMART SM00079 34 254 5.7E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 533 714 1.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 510 608 3.3E-31 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 SMART SM00062 34 255 1.7E-58 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 SMART SM00062 269 491 4.4E-58 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Gene3D G3DSA:3.40.190.10 134 216 5.9E-18 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Gene3D G3DSA:3.40.190.10 370 452 2.7E-20 T 28-03-2018 CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 272 489 7.7E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS02655 838bed347662f0930e5570dfff5c7c64 720 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 254 1.1E-59 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS04525 89a9c6b10b14af920c6f21aecbb0c7f7 230 Pfam PF02581 Thiamine monophosphate synthase 26 214 7.0E-54 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04525 89a9c6b10b14af920c6f21aecbb0c7f7 230 SUPERFAMILY SSF51391 15 228 3.79E-53 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04525 89a9c6b10b14af920c6f21aecbb0c7f7 230 Gene3D G3DSA:3.20.20.70 15 229 4.9E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS04525 89a9c6b10b14af920c6f21aecbb0c7f7 230 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 24 230 23.633 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04525 89a9c6b10b14af920c6f21aecbb0c7f7 230 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 26 227 9.0E-58 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 4.0E-12 T 28-03-2018 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 4.0E-12 T 28-03-2018 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 4.0E-12 T 28-03-2018 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 4.0E-12 T 28-03-2018 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 Pfam PF07690 Major Facilitator Superfamily 18 409 3.5E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 SUPERFAMILY SSF103473 458 487 3.66E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 SUPERFAMILY SSF103473 10 200 3.66E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 SUPERFAMILY SSF103473 248 419 3.66E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 Gene3D G3DSA:1.20.1250.20 250 491 2.2E-29 T 28-03-2018 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 Gene3D G3DSA:1.20.1250.20 8 195 2.0E-29 T 28-03-2018 CPF12_RS10715 91f3b96c8b0070ec47253d73a43992be 493 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 485 6.1E-120 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS04095 ea197ac517080cd2221716d982e81b68 261 Gene3D G3DSA:3.40.50.300 1 252 4.7E-59 T 28-03-2018 CPF12_RS04095 ea197ac517080cd2221716d982e81b68 261 Pfam PF00005 ABC transporter 20 167 1.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04095 ea197ac517080cd2221716d982e81b68 261 SUPERFAMILY SSF52540 4 229 1.78E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04095 ea197ac517080cd2221716d982e81b68 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS04095 ea197ac517080cd2221716d982e81b68 261 SMART SM00382 28 217 3.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS10905 1dbb0e7ecc186f8cb68044352c6a3b6c 386 Gene3D G3DSA:1.20.1250.20 6 191 5.2E-31 T 28-03-2018 CPF12_RS10905 1dbb0e7ecc186f8cb68044352c6a3b6c 386 SUPERFAMILY SSF103473 3 378 1.01E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10905 1dbb0e7ecc186f8cb68044352c6a3b6c 386 Pfam PF07690 Major Facilitator Superfamily 11 311 4.5E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS10905 1dbb0e7ecc186f8cb68044352c6a3b6c 386 Gene3D G3DSA:1.20.1250.20 192 385 2.1E-14 T 28-03-2018 CPF12_RS01595 3d8e7f1914a50a4b09cda703e650d3bf 149 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 34 1.4E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CPF12_RS01595 3d8e7f1914a50a4b09cda703e650d3bf 149 Pfam PF07963 Prokaryotic N-terminal methylation motif 14 30 1.4E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 SUPERFAMILY SSF54768 116 227 7.07E-22 T 28-03-2018 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 Gene3D G3DSA:3.30.160.20 158 233 2.9E-22 T 28-03-2018 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 7 224 3.7E-79 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 SUPERFAMILY SSF69065 3 158 9.24E-51 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 SMART SM00535 19 154 3.1E-53 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 SMART SM00358 160 227 4.4E-21 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 Pfam PF14622 Ribonuclease-III-like 18 148 9.9E-35 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 Pfam PF00035 Double-stranded RNA binding motif 160 224 2.8E-15 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 223 30.648 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 ProSitePatterns PS00517 Ribonuclease III family signature. 43 51 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS11540 459b6de669b46a60981a3052e5e00fd9 233 Gene3D G3DSA:1.10.1520.10 3 152 2.6E-45 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CPF12_RS01620 420d05ac2cb8f2e34d58c9cdda7c3ec4 306 Gene3D G3DSA:3.20.20.20 2 147 5.9E-4 T 28-03-2018 CPF12_RS01620 420d05ac2cb8f2e34d58c9cdda7c3ec4 306 Pfam PF01136 Peptidase family U32 72 303 3.6E-37 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CPF12_RS11065 111f83b4262821dd44e59a1cbc19afd7 308 SMART SM00849 18 201 0.002 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11065 111f83b4262821dd44e59a1cbc19afd7 308 Pfam PF00753 Metallo-beta-lactamase superfamily 33 119 1.1E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11065 111f83b4262821dd44e59a1cbc19afd7 308 SUPERFAMILY SSF56281 1 304 2.75E-85 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11065 111f83b4262821dd44e59a1cbc19afd7 308 Hamap MF_01818 Ribonuclease BN [rbn]. 1 304 40.298 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CPF12_RS11065 111f83b4262821dd44e59a1cbc19afd7 308 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 1.1E-112 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CPF12_RS11065 111f83b4262821dd44e59a1cbc19afd7 308 Gene3D G3DSA:3.60.15.10 1 308 3.2E-62 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS06700 a225abd085cf0d61014456f1d9406222 301 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 13 297 1.8E-85 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CPF12_RS06700 a225abd085cf0d61014456f1d9406222 301 SUPERFAMILY SSF161098 33 291 1.27E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06700 a225abd085cf0d61014456f1d9406222 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 297 1.4E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06700 a225abd085cf0d61014456f1d9406222 301 Gene3D G3DSA:1.10.3720.10 3 292 1.6E-35 T 28-03-2018 CPF12_RS02160 280b2471e48c969ae6810a69e8ba07b6 217 Gene3D G3DSA:3.40.50.1820 126 217 1.9E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS02160 280b2471e48c969ae6810a69e8ba07b6 217 SUPERFAMILY SSF53474 3 217 2.24E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS02160 280b2471e48c969ae6810a69e8ba07b6 217 Gene3D G3DSA:3.40.50.1820 2 125 1.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS02160 280b2471e48c969ae6810a69e8ba07b6 217 Pfam PF00561 alpha/beta hydrolase fold 19 125 1.7E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 Gene3D G3DSA:3.40.50.880 141 358 6.2E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 131 4.5E-54 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 354 7.0E-152 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 Pfam PF00117 Glutamine amidotransferase class-I 174 351 2.4E-47 T 28-03-2018 IPR017926 Glutamine amidotransferase CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 Gene3D G3DSA:3.50.30.20 1 140 8.9E-62 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 2.6E-38 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 2.6E-38 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 2.6E-38 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 2.6E-38 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 2.6E-38 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00097 Anthranilate synthase component II signature 328 341 2.0E-8 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00097 Anthranilate synthase component II signature 242 253 2.0E-8 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00097 Anthranilate synthase component II signature 215 224 2.0E-8 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 SMART SM01097 2 132 2.0E-90 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 357 49.566 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 SUPERFAMILY SSF52021 2 144 6.15E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 SUPERFAMILY SSF52317 147 355 1.8E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 328 341 9.3E-13 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 9.3E-13 T 28-03-2018 CPF12_RS11330 f5658a1d1b810f5ca71f407d91e0776d 363 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 9.3E-13 T 28-03-2018 CPF12_RS10835 c34767fd3c52391bb60f7e9d68c6b7d3 216 TIGRFAM TIGR03579 EF_0833: conserved hypothetical protein EF_0833/AHA_3914 9 216 1.0E-111 T 28-03-2018 IPR025456 Protein of unknown function DUF4310 CPF12_RS10835 c34767fd3c52391bb60f7e9d68c6b7d3 216 Pfam PF14187 Domain of unknown function (DUF4310) 7 214 3.0E-106 T 28-03-2018 IPR025456 Protein of unknown function DUF4310 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 SUPERFAMILY SSF55008 2 67 1.1E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 Gene3D G3DSA:3.30.70.100 1 68 1.4E-20 T 28-03-2018 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 Pfam PF00403 Heavy-metal-associated domain 6 66 5.0E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 PRINTS PR00944 Copper ion binding protein signature 54 67 1.7E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 PRINTS PR00944 Copper ion binding protein signature 3 15 1.7E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 PRINTS PR00944 Copper ion binding protein signature 15 28 1.7E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 PRINTS PR00944 Copper ion binding protein signature 28 41 1.7E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CPF12_RS07510 10f668b3a848c5caa29919a4307571af 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 6 67 1.7E-21 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 Gene3D G3DSA:1.10.275.10 1 131 2.2E-56 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 Gene3D G3DSA:1.20.200.10 132 408 5.4E-86 T 28-03-2018 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 Gene3D G3DSA:1.10.40.30 409 455 1.2E-22 T 28-03-2018 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 454 5.0E-215 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 SUPERFAMILY SSF48557 3 453 2.2E-146 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 Pfam PF10415 Fumarase C C-terminus 402 455 8.4E-23 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 PRINTS PR00149 Fumarate lyase superfamily signature 174 192 7.8E-33 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 PRINTS PR00149 Fumarate lyase superfamily signature 128 146 7.8E-33 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 7.8E-33 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 PRINTS PR00149 Fumarate lyase superfamily signature 311 327 7.8E-33 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 Pfam PF00206 Lyase 11 336 5.4E-110 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 456 84.139 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CPF12_RS02275 8b35e14fd9c293aad08e73ed002a0fbc 461 ProSitePatterns PS00163 Fumarate lyases signature. 311 320 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 ProSitePatterns PS00756 Protein secY signature 2. 164 181 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 SUPERFAMILY SSF103491 1 421 1.57E-124 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 28.767 T 28-03-2018 IPR026593 Protein translocase subunit SecY CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 7.8E-143 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 Pfam PF00344 SecY translocase 67 414 2.9E-110 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 66 86 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 171 194 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 145 170 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 108 131 2.8E-100 T 28-03-2018 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 ProSitePatterns PS00755 Protein secY signature 1. 67 86 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 PIRSF PIRSF004557 1 431 9.5E-129 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CPF12_RS06160 602cbea2c769b698dc93f9d940d777b1 431 Gene3D G3DSA:1.10.3370.10 1 431 7.3E-152 T 28-03-2018 CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 Gene3D G3DSA:3.30.230.10 77 167 2.2E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 SUPERFAMILY SSF54768 9 77 5.86E-25 T 28-03-2018 CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 Pfam PF00333 Ribosomal protein S5, N-terminal domain 12 73 5.1E-32 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 Gene3D G3DSA:3.30.160.20 11 73 1.2E-31 T 28-03-2018 CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 164 34.97 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 11 164 1.1E-66 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 ProSitePatterns PS00585 Ribosomal protein S5 signature. 29 61 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 SUPERFAMILY SSF54211 80 159 1.62E-23 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS06145 aea7ddad9f5b5d68bb4837459539d715 167 Pfam PF03719 Ribosomal protein S5, C-terminal domain 88 158 1.2E-27 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CPF12_RS07595 3daf7fd7df36e9c971aa7d1e2f0e2295 248 Gene3D G3DSA:3.40.395.10 3 98 0.022 T 28-03-2018 CPF12_RS07815 6a0c6d981bc07db479d0379e40ff09a2 274 Gene3D G3DSA:3.40.190.10 130 273 6.7E-42 T 28-03-2018 CPF12_RS07815 6a0c6d981bc07db479d0379e40ff09a2 274 PIRSF PIRSF002854 1 274 1.4E-95 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS07815 6a0c6d981bc07db479d0379e40ff09a2 274 SUPERFAMILY SSF53850 34 273 1.31E-74 T 28-03-2018 CPF12_RS07815 6a0c6d981bc07db479d0379e40ff09a2 274 Gene3D G3DSA:3.40.190.10 34 129 1.6E-28 T 28-03-2018 CPF12_RS07815 6a0c6d981bc07db479d0379e40ff09a2 274 Pfam PF03180 NLPA lipoprotein 35 273 3.0E-81 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS09845 82ef93413c16b01dd0738e2ff477c48e 110 Pfam PF00085 Thioredoxin 5 101 2.6E-17 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CPF12_RS09845 82ef93413c16b01dd0738e2ff477c48e 110 Gene3D G3DSA:3.40.30.10 1 109 2.6E-21 T 28-03-2018 CPF12_RS09845 82ef93413c16b01dd0738e2ff477c48e 110 SUPERFAMILY SSF52833 3 103 2.96E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 6.3E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 3.3E-16 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 323 2.7E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Pfam PF07724 AAA domain (Cdc48 subfamily) 535 706 1.9E-54 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Pfam PF02151 UvrB/uvrC motif 416 446 5.7E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 713 792 6.0E-27 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Gene3D G3DSA:1.10.8.60 343 486 2.6E-42 T 28-03-2018 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 SUPERFAMILY SSF52540 485 796 2.02E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Gene3D G3DSA:1.10.8.60 713 825 5.2E-28 T 28-03-2018 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 SUPERFAMILY SSF81923 5 137 3.34E-26 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 570 588 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 SMART SM01086 713 803 1.0E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Gene3D G3DSA:1.10.1780.10 76 191 3.8E-27 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Gene3D G3DSA:1.10.1780.10 1 75 6.3E-22 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Gene3D G3DSA:3.40.50.300 491 712 2.4E-53 T 28-03-2018 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 540 558 1.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 585 603 1.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 661 1.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 614 632 1.0E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 Gene3D G3DSA:3.40.50.300 192 341 7.7E-21 T 28-03-2018 CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 SMART SM00382 536 676 2.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 SMART SM00382 199 344 5.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05920 71f6bcab199b69a54797e829cf16af6b 833 SUPERFAMILY SSF52540 160 465 1.02E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 SMART SM00448 1 113 4.9E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 Gene3D G3DSA:2.40.50.40 124 192 3.4E-17 T 28-03-2018 CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 Pfam PF00072 Response regulator receiver domain 3 113 2.4E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 Pfam PF04397 LytTr DNA-binding domain 136 220 7.5E-15 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 SUPERFAMILY SSF52172 1 117 1.71E-21 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 Gene3D G3DSA:3.40.50.2300 1 123 2.3E-21 T 28-03-2018 CPF12_RS11975 b1bda6f242495d17487d13e277209ba7 234 SMART SM00850 133 227 1.0E-13 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS10410 6172a8834eef002f4747067bad43df8c 202 Gene3D G3DSA:3.40.1350.10 33 199 4.5E-61 T 28-03-2018 CPF12_RS10410 6172a8834eef002f4747067bad43df8c 202 PIRSF PIRSF037785 23 202 3.1E-72 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CPF12_RS10410 6172a8834eef002f4747067bad43df8c 202 Pfam PF03838 Recombination protein U 32 196 4.4E-65 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CPF12_RS10410 6172a8834eef002f4747067bad43df8c 202 SUPERFAMILY SSF52980 34 200 7.24E-64 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CPF12_RS10410 6172a8834eef002f4747067bad43df8c 202 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 202 87.743 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CPF12_RS10410 6172a8834eef002f4747067bad43df8c 202 TIGRFAM TIGR00648 recU: recombination protein U 32 198 1.6E-68 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 18 35 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 Pfam PF02378 Phosphotransferase system, EIIC 111 412 6.8E-59 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 465 6.1E-184 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 Pfam PF00367 phosphotransferase system, EIIB 9 40 1.3E-10 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 Gene3D G3DSA:3.30.1360.60 4 80 1.4E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 27 110 9.2E-14 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS07875 abab1c930563bf9672609632173d2967 481 SUPERFAMILY SSF55604 7 81 9.68E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 SUPERFAMILY SSF53955 79 288 4.78E-66 T 28-03-2018 IPR023346 Lysozyme-like domain CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 SUPERFAMILY SSF56601 245 267 1.69E-102 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 SUPERFAMILY SSF56601 305 701 1.69E-102 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 648 4.6E-36 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 Pfam PF00912 Transglycosylase 88 263 1.8E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 Gene3D G3DSA:1.10.3810.10 80 280 7.2E-71 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 98 653 5.6E-172 T 28-03-2018 CPF12_RS10405 852d67c4389528ba4db8396b9eb99ce2 796 Gene3D G3DSA:3.40.710.10 282 667 3.4E-88 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 Pfam PF00122 E1-E2 ATPase 106 284 1.6E-31 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF81653 110 202 9.94E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 5 678 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 3 681 40.138 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 Gene3D G3DSA:3.40.50.1000 444 576 8.4E-33 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 Gene3D G3DSA:2.70.150.10 3 203 1.6E-25 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 372 606 3.9E-46 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 67 342 1.7E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 Pfam PF00702 haloacid dehalogenase-like hydrolase 303 531 7.0E-32 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF56784 376 405 1.62E-37 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF56784 436 560 1.62E-37 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF56784 294 318 1.62E-37 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF81665 16 98 1.83E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF81665 566 572 1.83E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF81665 203 300 1.83E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 Gene3D G3DSA:3.40.1110.10 317 443 1.6E-20 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 464 474 4.0E-24 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 306 320 4.0E-24 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 552 4.0E-24 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 536 4.0E-24 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 4.0E-24 T 28-03-2018 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 308 314 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CPF12_RS10655 80465062347332e5bcb3f2575bae1a5d 683 SUPERFAMILY SSF81660 317 451 2.26E-33 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CPF12_RS06085 0f0e222ce9308b71e759abe8ce91e33d 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 87 111 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06085 0f0e222ce9308b71e759abe8ce91e33d 114 SUPERFAMILY SSF54843 6 114 7.85E-43 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06085 0f0e222ce9308b71e759abe8ce91e33d 114 Gene3D G3DSA:3.90.470.10 1 114 2.2E-42 T 28-03-2018 CPF12_RS06085 0f0e222ce9308b71e759abe8ce91e33d 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 9 111 1.9E-49 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06085 0f0e222ce9308b71e759abe8ce91e33d 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 5 114 29.532 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06085 0f0e222ce9308b71e759abe8ce91e33d 114 Pfam PF00237 Ribosomal protein L22p/L17e 10 112 2.4E-36 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 421 1.4E-76 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 SUPERFAMILY SSF53187 296 325 3.14E-52 T 28-03-2018 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 SUPERFAMILY SSF53187 372 432 3.14E-52 T 28-03-2018 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 SUPERFAMILY SSF53187 6 196 3.14E-52 T 28-03-2018 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 Pfam PF01546 Peptidase family M20/M25/M40 75 320 9.9E-7 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 Gene3D G3DSA:3.40.630.10 366 454 2.8E-13 T 28-03-2018 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 Gene3D G3DSA:3.40.630.10 3 360 1.4E-37 T 28-03-2018 CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 PIRSF PIRSF037227 2 464 1.7E-189 T 28-03-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 Pfam PF07687 Peptidase dimerisation domain 186 276 8.2E-6 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS01040 bd32464b2d7dda0c70363a96f5e16586 465 SUPERFAMILY SSF55031 185 289 1.94E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS07645 4c63efd21465ccfc6c550c8a433c77dd 444 PIRSF PIRSF006351 1 444 2.3E-116 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CPF12_RS07645 4c63efd21465ccfc6c550c8a433c77dd 444 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 11 437 7.4E-102 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CPF12_RS07645 4c63efd21465ccfc6c550c8a433c77dd 444 Pfam PF02378 Phosphotransferase system, EIIC 28 367 1.4E-38 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS03405 1197ecb3d7f7b0c393864125ea738729 325 Gene3D G3DSA:3.40.718.10 18 323 1.3E-60 T 28-03-2018 CPF12_RS03405 1197ecb3d7f7b0c393864125ea738729 325 PIRSF PIRSF000428 1 325 5.4E-101 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CPF12_RS03405 1197ecb3d7f7b0c393864125ea738729 325 SUPERFAMILY SSF53659 5 322 1.64E-91 T 28-03-2018 CPF12_RS03405 1197ecb3d7f7b0c393864125ea738729 325 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 5.3E-109 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CPF12_RS03405 1197ecb3d7f7b0c393864125ea738729 325 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 319 1.4E-112 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 SMART SM00849 21 217 7.2E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 PIRSF PIRSF004803 2 557 4.8E-194 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 Pfam PF00753 Metallo-beta-lactamase superfamily 21 173 4.2E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 Gene3D G3DSA:3.60.15.10 2 450 1.2E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 555 1.3E-181 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 SUPERFAMILY SSF56281 9 425 2.54E-72 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 Hamap MF_01491 Ribonuclease J [rnj]. 4 557 41.814 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CPF12_RS12115 97c297a09339e982cee4d3adcf7017c4 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 367 405 1.8E-10 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CPF12_RS00590 1e2b3bdbb665720ea725cbe1266059f1 567 Gene3D G3DSA:3.40.50.300 51 440 0.024 T 28-03-2018 CPF12_RS00590 1e2b3bdbb665720ea725cbe1266059f1 567 TIGRFAM TIGR03238 dnd_assoc_3: DNA phosphorothioation-dependent restriction protein DptF 32 544 5.5E-63 T 28-03-2018 IPR017647 DNA phosphorothioation-dependent restriction protein DptF CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 SUPERFAMILY SSF56112 8 269 3.37E-81 T 28-03-2018 IPR011009 Protein kinase-like domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 Pfam PF00069 Protein kinase domain 11 261 2.9E-54 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 SMART SM00220 11 268 2.7E-71 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 SMART SM00740 429 497 5.4E-10 T 28-03-2018 IPR005543 PASTA domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 SMART SM00740 361 428 2.1E-15 T 28-03-2018 IPR005543 PASTA domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 SMART SM00740 498 564 3.1E-13 T 28-03-2018 IPR005543 PASTA domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 Gene3D G3DSA:3.30.200.20 9 78 2.7E-22 T 28-03-2018 CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 Pfam PF03793 PASTA domain 435 496 1.2E-11 T 28-03-2018 IPR005543 PASTA domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 Pfam PF03793 PASTA domain 503 564 4.3E-13 T 28-03-2018 IPR005543 PASTA domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 Pfam PF03793 PASTA domain 366 427 3.3E-13 T 28-03-2018 IPR005543 PASTA domain CPF12_RS11470 395712d13ceb768a5d26251cbb1dbf15 672 Gene3D G3DSA:1.10.510.10 79 639 1.6E-55 T 28-03-2018 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 Gene3D G3DSA:3.20.10.10 164 328 3.1E-39 T 28-03-2018 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 SUPERFAMILY SSF56752 4 336 1.7E-101 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 Pfam PF01063 Amino-transferase class IV 58 293 2.3E-36 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 PIRSF PIRSF006468 1 339 1.1E-115 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 Gene3D G3DSA:3.30.470.10 1 163 1.9E-54 T 28-03-2018 CPF12_RS10505 3a45871f4f00e5aae9c1e57f07961bb9 339 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 31 339 2.7E-136 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 SUPERFAMILY SSF64288 76 229 4.4E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 SMART SM00345 7 66 2.6E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 SMART SM00866 87 226 6.8E-25 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 Gene3D G3DSA:1.10.10.10 2 72 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.4E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 Pfam PF07702 UTRA domain 91 223 6.6E-27 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 Gene3D G3DSA:3.40.1410.10 73 233 2.7E-28 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CPF12_RS07850 a558a902e08258c567ce6e06cb66bd57 236 SUPERFAMILY SSF46785 5 76 7.35E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 Pfam PF00232 Glycosyl hydrolase family 1 3 457 7.7E-125 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 425 437 6.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 286 300 6.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 401 418 6.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 356 364 6.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 380 391 6.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 SUPERFAMILY SSF51445 2 451 8.86E-148 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07630 7f1d7a41e05d1696d83f7c7441e5e38f 459 Gene3D G3DSA:3.20.20.80 2 457 1.4E-136 T 28-03-2018 CPF12_RS00295 87a7f4570ce49968f707b7f5fe44f935 489 Pfam PF12010 Domain of unknown function (DUF3502) 356 485 3.6E-36 T 28-03-2018 IPR022627 Domain of unknown function DUF3502 CPF12_RS00295 87a7f4570ce49968f707b7f5fe44f935 489 Gene3D G3DSA:3.40.190.10 284 408 0.0014 T 28-03-2018 CPF12_RS00295 87a7f4570ce49968f707b7f5fe44f935 489 SUPERFAMILY SSF53850 22 485 3.03E-77 T 28-03-2018 CPF12_RS00295 87a7f4570ce49968f707b7f5fe44f935 489 Gene3D G3DSA:3.40.190.10 39 216 5.5E-22 T 28-03-2018 CPF12_RS00295 87a7f4570ce49968f707b7f5fe44f935 489 Pfam PF13416 Bacterial extracellular solute-binding protein 68 346 4.7E-14 T 28-03-2018 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 Pfam PF00107 Zinc-binding dehydrogenase 172 298 1.6E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 SMART SM00829 8 332 1.7E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 Gene3D G3DSA:3.40.50.720 144 327 1.8E-34 T 28-03-2018 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 1.5E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 SUPERFAMILY SSF51735 135 302 4.35E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 Gene3D G3DSA:3.90.180.10 1 143 1.8E-43 T 28-03-2018 CPF12_RS11160 fb46aa3f6d50546ffd1321f2f7939751 336 SUPERFAMILY SSF50129 1 167 1.03E-45 T 28-03-2018 IPR011032 GroES-like CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 SUPERFAMILY SSF52540 1 427 8.92E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 Gene3D G3DSA:3.90.170.10 265 429 7.1E-70 T 28-03-2018 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 SMART SM00788 3 422 1.4E-292 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 Gene3D G3DSA:3.40.440.10 149 264 5.1E-29 T 28-03-2018 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 Gene3D G3DSA:3.40.440.10 1 148 2.4E-50 T 28-03-2018 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 Pfam PF00709 Adenylosuccinate synthetase 4 421 1.8E-181 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 208.06 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CPF12_RS05330 3a568525a22151d8b482b88bb2cb6718 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 2.0E-187 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CPF12_RS00875 ef36f8d4517ac7e301f5410e15ff6e90 534 SMART SM00382 49 229 2.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00875 ef36f8d4517ac7e301f5410e15ff6e90 534 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00875 ef36f8d4517ac7e301f5410e15ff6e90 534 Gene3D G3DSA:3.40.50.300 1 375 3.2E-51 T 28-03-2018 CPF12_RS00875 ef36f8d4517ac7e301f5410e15ff6e90 534 Pfam PF00005 ABC transporter 40 171 2.2E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00875 ef36f8d4517ac7e301f5410e15ff6e90 534 SUPERFAMILY SSF52540 21 238 5.43E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07350 97c75488dc00c403d88ce3ee914b8db3 134 SUPERFAMILY SSF52218 5 125 2.42E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS07350 97c75488dc00c403d88ce3ee914b8db3 134 Pfam PF02525 Flavodoxin-like fold 7 120 6.2E-21 T 28-03-2018 IPR003680 Flavodoxin-like fold CPF12_RS07350 97c75488dc00c403d88ce3ee914b8db3 134 Gene3D G3DSA:3.40.50.360 1 133 2.9E-19 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 706 730 0.014 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 607 651 2.6E-6 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 527 1.8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 600 0.0034 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 657 699 1.2E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 7 745 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Gene3D G3DSA:3.30.1360.40 235 331 4.6E-33 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Gene3D G3DSA:3.90.199.10 33 213 1.3E-76 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 SUPERFAMILY SSF101904 499 804 7.46E-80 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 SUPERFAMILY SSF56719 30 485 5.62E-163 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 463 2.8E-146 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Gene3D G3DSA:2.120.10.90 499 806 3.3E-75 T 28-03-2018 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Gene3D G3DSA:1.10.268.10 343 485 1.4E-41 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 SMART SM00434 10 463 5.4E-242 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CPF12_RS11845 d6cb13efc6d1f99652320eab3f534ea2 809 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 804 32.311 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 Gene3D G3DSA:3.40.50.1370 161 326 1.1E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 13 323 1.4E-116 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 322 1.5E-54 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 SUPERFAMILY SSF53671 7 324 8.25E-93 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 Gene3D G3DSA:3.40.50.1370 4 160 2.0E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 4 325 74.29 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 289 312 3.2E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 3.2E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 3.2E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 3.2E-22 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 145 6.5E-42 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 7.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 7.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 7.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00102 Ornithine carbamoyltransferase signature 224 234 7.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS06370 e8408673cde74f7ce1c75b703e559951 327 PRINTS PR00102 Ornithine carbamoyltransferase signature 303 314 7.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 194 1.9E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 224 7.4E-85 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 2.7E-26 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 Gene3D G3DSA:3.40.50.1000 91 232 9.7E-28 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 Gene3D G3DSA:3.40.50.1000 1 31 0.074 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 SUPERFAMILY SSF56784 3 224 2.71E-46 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 Gene3D G3DSA:1.10.150.240 32 90 1.0E-21 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CPF12_RS02960 82120588e5672a00ba64332ed0c0d42c 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 75 200 7.4E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 PRINTS PR00315 GTP-binding elongation factor signature 64 72 3.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.2E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Pfam PF00009 Elongation factor Tu GTP binding domain 14 276 1.6E-49 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 SUPERFAMILY SSF50447 260 390 8.84E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 SUPERFAMILY SSF52540 8 276 6.86E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 3 522 3.6E-198 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Pfam PF16658 Class II release factor RF3, C-terminal domain 387 511 1.9E-44 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Gene3D G3DSA:3.30.70.870 393 465 3.8E-10 T 28-03-2018 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Gene3D G3DSA:3.40.50.300 5 272 1.6E-38 T 28-03-2018 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Gene3D G3DSA:2.40.30.10 273 390 9.6E-23 T 28-03-2018 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 152 1.3E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 SUPERFAMILY SSF54980 393 465 1.83E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 3 524 49.339 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CPF12_RS02550 803d2d6c798aef2634d4048f8a64a50b 524 Pfam PF03144 Elongation factor Tu domain 2 313 379 2.4E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 PIRSF PIRSF004803 1 556 1.0E-238 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 SMART SM00849 21 215 4.8E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 554 5.5E-210 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 403 2.8E-10 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 SUPERFAMILY SSF56281 11 423 4.44E-91 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.6E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 Gene3D G3DSA:3.60.15.10 2 448 8.2E-61 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS01425 c46b641923c8e45ed02fc21bb654345a 558 Hamap MF_01491 Ribonuclease J [rnj]. 4 556 46.516 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CPF12_RS03260 c1138cda4ae41a506d4b1d662387913e 254 Pfam PF02666 Phosphatidylserine decarboxylase 60 251 3.5E-47 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CPF12_RS03260 c1138cda4ae41a506d4b1d662387913e 254 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 52 203 1.0E-41 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CPF12_RS00250 0e532e357b4bc9f81ef1d04ed7194b2d 493 Gene3D G3DSA:3.30.1360.60 4 78 2.8E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00250 0e532e357b4bc9f81ef1d04ed7194b2d 493 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS00250 0e532e357b4bc9f81ef1d04ed7194b2d 493 SUPERFAMILY SSF55604 8 80 7.19E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00250 0e532e357b4bc9f81ef1d04ed7194b2d 493 Pfam PF00367 phosphotransferase system, EIIB 10 43 9.8E-16 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS00250 0e532e357b4bc9f81ef1d04ed7194b2d 493 Pfam PF02378 Phosphotransferase system, EIIC 110 428 9.4E-30 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00690 Adhesin family signature 83 100 3.5E-47 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00690 Adhesin family signature 202 223 3.5E-47 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00690 Adhesin family signature 39 57 3.5E-47 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00690 Adhesin family signature 255 273 3.5E-47 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00690 Adhesin family signature 70 83 3.5E-47 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00690 Adhesin family signature 282 301 3.5E-47 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 64 82 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 295 313 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 83 102 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 144 163 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 202 219 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 39 60 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 228 246 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 PRINTS PR00691 Adhesin B signature 251 268 6.8E-67 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 SUPERFAMILY SSF53807 18 317 2.31E-84 T 28-03-2018 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 Pfam PF01297 Zinc-uptake complex component A periplasmic 42 314 4.6E-75 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 Gene3D G3DSA:3.40.50.1980 28 196 5.9E-46 T 28-03-2018 CPF12_RS03905 e4f4f90bb45dcba2cfdf31d8b2e2eec0 318 Gene3D G3DSA:3.40.50.1980 197 317 3.7E-33 T 28-03-2018 CPF12_RS07280 a8ba49e380e29d740de2f31585718c65 319 Gene3D G3DSA:3.10.180.10 151 319 3.5E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS07280 a8ba49e380e29d740de2f31585718c65 319 SUPERFAMILY SSF54593 8 309 1.37E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS07280 a8ba49e380e29d740de2f31585718c65 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 279 6.2E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS07280 a8ba49e380e29d740de2f31585718c65 319 Gene3D G3DSA:3.10.180.10 7 135 1.2E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 Pfam PF01189 16S rRNA methyltransferase RsmB/F 247 442 4.3E-61 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 SUPERFAMILY SSF53335 142 443 4.14E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 SUPERFAMILY SSF48013 6 132 2.22E-33 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 Pfam PF01029 NusB family 7 129 9.6E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 Gene3D G3DSA:3.40.50.150 239 445 3.5E-55 T 28-03-2018 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 Gene3D G3DSA:1.10.940.10 2 147 1.4E-28 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 8 442 1.2E-135 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 326 338 6.5E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 229 243 6.5E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 258 268 6.5E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 376 392 6.5E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 426 443 6.5E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS11460 9ed5f7a21fdef207201d8a4f08ae4dbc 445 Gene3D G3DSA:3.30.70.1170 173 238 9.9E-13 T 28-03-2018 CPF12_RS05360 3deec589e251713974e005681575a225 659 Pfam PF01368 DHH family 341 500 1.8E-18 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CPF12_RS05360 3deec589e251713974e005681575a225 659 Pfam PF02272 DHHA1 domain 522 651 7.1E-11 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CPF12_RS05360 3deec589e251713974e005681575a225 659 Gene3D G3DSA:3.90.1640.10 319 540 7.8E-48 T 28-03-2018 CPF12_RS05360 3deec589e251713974e005681575a225 659 SMART SM00267 132 301 1.0E-4 T 28-03-2018 IPR000160 GGDEF domain CPF12_RS05360 3deec589e251713974e005681575a225 659 PIRSF PIRSF026583 1 659 2.1E-251 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CPF12_RS05360 3deec589e251713974e005681575a225 659 SUPERFAMILY SSF64182 340 641 1.96E-68 T 28-03-2018 CPF12_RS03745 19b0624e7a2a81998748d2ce067885d4 114 Gene3D G3DSA:1.10.260.40 1 113 1.0E-4 T 28-03-2018 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SUPERFAMILY SSF55874 441 607 5.37E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 498 607 4.1E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SUPERFAMILY SSF158472 213 262 6.28E-9 T 28-03-2018 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Pfam PF00672 HAMP domain 213 261 1.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Gene3D G3DSA:1.10.287.130 382 448 1.6E-16 T 28-03-2018 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 548 2.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 587 2.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 562 2.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 606 2.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Gene3D G3DSA:3.30.450.20 35 187 3.4E-15 T 28-03-2018 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SUPERFAMILY SSF47384 370 453 3.53E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Gene3D G3DSA:3.30.565.10 469 617 1.1E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SMART SM00091 272 338 1.4E-6 T 28-03-2018 IPR000014 PAS domain CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 272 386 1.3E-7 T 28-03-2018 IPR000014 PAS domain CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SMART SM00304 213 265 4.2E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Pfam PF00989 PAS fold 274 335 1.7E-9 T 28-03-2018 IPR013767 PAS fold GO:0006355 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Pfam PF00512 His Kinase A (phospho-acceptor) domain 386 452 1.0E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SMART SM00387 497 609 1.5E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SMART SM00388 385 452 7.4E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 Gene3D G3DSA:3.30.450.20 258 381 7.1E-20 T 28-03-2018 CPF12_RS05035 505f10a6bce6a71bf0ef2761c304f02d 619 SUPERFAMILY SSF55785 262 377 5.76E-11 T 28-03-2018 IPR000014 PAS domain CPF12_RS04320 676df00520256671e560a33806f27a5d 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 55 255 2.0E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04320 676df00520256671e560a33806f27a5d 260 SUPERFAMILY SSF161098 2 255 6.41E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04320 676df00520256671e560a33806f27a5d 260 Gene3D G3DSA:1.10.3720.10 1 259 3.8E-34 T 28-03-2018 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 SUPERFAMILY SSF53067 3 171 9.18E-68 T 28-03-2018 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 SUPERFAMILY SSF53067 118 347 7.53E-52 T 28-03-2018 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 Gene3D G3DSA:3.30.420.40 2 179 1.3E-55 T 28-03-2018 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 Hamap MF_00542 Probable butyrate kinase [buk]. 1 363 148.312 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 Gene3D G3DSA:3.30.420.40 180 354 1.6E-45 T 28-03-2018 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 Pfam PF00871 Acetokinase family 4 350 6.0E-61 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 353 1.2E-154 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 PIRSF PIRSF036458 1 356 6.2E-155 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 PRINTS PR00471 Acetate kinase family signature 274 287 7.1E-18 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 PRINTS PR00471 Acetate kinase family signature 297 313 7.1E-18 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 PRINTS PR00471 Acetate kinase family signature 149 162 7.1E-18 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 PRINTS PR00471 Acetate kinase family signature 5 16 7.1E-18 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS01810 f176b61bb2aa9dc0fc65c8f768e9b989 363 PRINTS PR00471 Acetate kinase family signature 179 200 7.1E-18 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS08040 b286a4f887d59a723f4810b60af77d79 256 SMART SM00943 7 161 1.2E-44 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CPF12_RS08040 b286a4f887d59a723f4810b60af77d79 256 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 7 160 6.1E-40 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CPF12_RS08040 b286a4f887d59a723f4810b60af77d79 256 SUPERFAMILY SSF56747 2 185 4.25E-40 T 28-03-2018 CPF12_RS08040 b286a4f887d59a723f4810b60af77d79 256 Pfam PF08708 Primase C terminal 1 (PriCT-1) 187 245 1.1E-10 T 28-03-2018 IPR014820 Primase, C-terminal 1 CPF12_RS08040 b286a4f887d59a723f4810b60af77d79 256 SMART SM00942 183 246 2.3E-12 T 28-03-2018 IPR014820 Primase, C-terminal 1 CPF12_RS12290 781d90c7b639a42b0a9b3065e25f25dc 730 Gene3D G3DSA:3.40.50.300 28 213 3.1E-6 T 28-03-2018 CPF12_RS12290 781d90c7b639a42b0a9b3065e25f25dc 730 Pfam PF00270 DEAD/DEAH box helicase 50 210 2.0E-5 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS12290 781d90c7b639a42b0a9b3065e25f25dc 730 SUPERFAMILY SSF52540 32 110 6.57E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12290 781d90c7b639a42b0a9b3065e25f25dc 730 SUPERFAMILY SSF52540 146 213 6.57E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12290 781d90c7b639a42b0a9b3065e25f25dc 730 Pfam PF10593 Z1 domain 300 513 8.3E-22 T 28-03-2018 IPR018310 Putative endonuclease, Z1 domain CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 5 253 5.7E-116 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 SUPERFAMILY SSF46785 169 257 5.73E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 Pfam PF08222 CodY helix-turn-helix domain 199 257 1.2E-36 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 260 137.683 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 Gene3D G3DSA:3.30.450.40 2 161 7.2E-27 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 PIRSF PIRSF011572 2 259 4.3E-116 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 Gene3D G3DSA:1.10.10.10 162 260 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11820 ac2e466ee863b2b119152d7bef5b501f 260 Pfam PF06018 CodY GAF-like domain 4 180 4.1E-74 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 291 317 1.8E-53 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 60 83 1.8E-53 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 123 142 1.8E-53 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 40 58 1.8E-53 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 178 198 1.8E-53 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 Gene3D G3DSA:3.90.640.10 186 243 9.7E-31 T 28-03-2018 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 Gene3D G3DSA:3.30.420.40 1 151 5.0E-36 T 28-03-2018 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 SUPERFAMILY SSF53067 3 139 1.71E-37 T 28-03-2018 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 Gene3D G3DSA:3.30.420.40 244 308 7.8E-8 T 28-03-2018 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 Pfam PF06723 MreB/Mbl protein 3 324 1.1E-147 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 Gene3D G3DSA:3.30.420.40 152 185 0.0015 T 28-03-2018 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 SUPERFAMILY SSF53067 141 324 6.68E-49 T 28-03-2018 CPF12_RS06515 21cdee3917ba6e1dcbbc00703055d9fa 327 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 323 1.2E-136 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CPF12_RS00195 05a5cb1438410caa1d4315f75dfa50de 217 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 4 217 1.3E-103 T 28-03-2018 IPR030983 Ethanolamine utilization protein EutL GO:0005198 CPF12_RS00195 05a5cb1438410caa1d4315f75dfa50de 217 SMART SM00877 34 121 5.4E-6 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00195 05a5cb1438410caa1d4315f75dfa50de 217 SMART SM00877 145 214 5.7E-5 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00195 05a5cb1438410caa1d4315f75dfa50de 217 SUPERFAMILY SSF143414 155 210 5.49E-5 T 28-03-2018 CPF12_RS00195 05a5cb1438410caa1d4315f75dfa50de 217 Pfam PF00936 BMC domain 35 106 1.2E-10 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00195 05a5cb1438410caa1d4315f75dfa50de 217 PIRSF PIRSF012290 1 217 4.9E-84 T 28-03-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 Pfam PF00455 DeoR C terminal sensor domain 76 231 1.7E-45 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 9.7E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 9.7E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 Gene3D G3DSA:1.10.10.10 3 72 5.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 SMART SM00420 6 58 5.6E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 SUPERFAMILY SSF46785 5 72 9.12E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 SMART SM01134 73 233 6.5E-54 T 28-03-2018 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 Gene3D G3DSA:3.40.50.1360 73 230 6.3E-32 T 28-03-2018 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 5.8E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07665 5929ddf3396b0240c523348adf8599de 251 SUPERFAMILY SSF100950 77 234 7.95E-26 T 28-03-2018 CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 Gene3D G3DSA:1.10.3100.10 1 100 4.5E-21 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 Gene3D G3DSA:2.10.109.10 101 220 8.4E-18 T 28-03-2018 CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 SUPERFAMILY SSF51306 84 216 1.96E-18 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 Pfam PF01381 Helix-turn-helix 8 63 9.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 SMART SM00530 7 63 3.0E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 SUPERFAMILY SSF47413 2 68 1.39E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS01335 298d6e6d4a23d3f5a9c421873668ddf1 221 Pfam PF00717 Peptidase S24-like 130 176 9.9E-9 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS05245 b518f61252332af9c5e9d3ca3f27121a 433 Gene3D G3DSA:2.70.70.10 208 433 5.3E-37 T 28-03-2018 CPF12_RS05245 b518f61252332af9c5e9d3ca3f27121a 433 Pfam PF01551 Peptidase family M23 326 417 3.0E-28 T 28-03-2018 IPR016047 Peptidase M23 CPF12_RS05245 b518f61252332af9c5e9d3ca3f27121a 433 SUPERFAMILY SSF51261 269 418 6.8E-42 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS02010 afe6a6d16d938cd3a32f7d2063a87a23 264 Hamap MF_00912 Cell division protein DivIB [divIB]. 12 256 24.656 T 28-03-2018 IPR026580 Cell division protein DivIB CPF12_RS02010 afe6a6d16d938cd3a32f7d2063a87a23 264 Pfam PF03799 Cell division protein FtsQ 128 242 6.4E-5 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CPF12_RS02010 afe6a6d16d938cd3a32f7d2063a87a23 264 Pfam PF08478 POTRA domain, FtsQ-type 53 120 2.5E-13 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 Pfam PF01479 S4 domain 15 61 3.5E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 Gene3D G3DSA:3.10.290.10 2 72 5.0E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 300 1.8E-103 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 Pfam PF00849 RNA pseudouridylate synthase 88 240 1.5E-35 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 SMART SM00363 15 79 5.5E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 SUPERFAMILY SSF55120 74 301 1.3E-79 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 Gene3D G3DSA:3.30.2350.10 79 303 1.9E-76 T 28-03-2018 CPF12_RS11305 96ef817e1d902a123d899d00fe0f04b5 310 SUPERFAMILY SSF55174 12 101 3.03E-15 T 28-03-2018 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 308 6.9E-35 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 SUPERFAMILY SSF51735 3 145 7.16E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 SUPERFAMILY SSF56327 144 307 3.03E-51 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 173 179 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 143 5.1E-42 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 Gene3D G3DSA:3.90.110.10 144 309 7.2E-46 T 28-03-2018 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 PIRSF PIRSF000102 2 313 3.6E-101 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 9 303 5.2E-117 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 Gene3D G3DSA:3.40.50.720 5 143 1.3E-32 T 28-03-2018 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 4 310 43.744 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 1.2E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 1.2E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 PRINTS PR00086 L-lactate dehydrogenase signature 31 55 1.2E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 PRINTS PR00086 L-lactate dehydrogenase signature 6 30 1.2E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS00135 0a4115a93c4b80eed1ee71ba0a2baa75 317 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 1.2E-42 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 297 57.668 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 Gene3D G3DSA:1.10.150.130 1 109 1.5E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 SUPERFAMILY SSF56349 5 290 1.0E-59 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 297 59.784 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 Pfam PF00589 Phage integrase family 112 283 2.1E-53 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 6 297 5.3E-118 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 86 4.1E-22 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CPF12_RS09385 72d0e8df3906c900a5573d6c16bde771 297 Gene3D G3DSA:1.10.443.10 110 291 6.4E-52 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 9 204 4.8E-84 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 209 250 4.3E-11 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Gene3D G3DSA:3.40.50.970 3 281 1.3E-65 T 28-03-2018 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 SUPERFAMILY SSF52518 4 348 8.75E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Pfam PF02779 Transketolase, pyrimidine binding domain 287 450 2.6E-33 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 209 591 7.0E-143 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Gene3D G3DSA:3.40.50.970 282 456 1.7E-40 T 28-03-2018 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 592 39.9 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Pfam PF02780 Transketolase, C-terminal domain 463 580 2.8E-26 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 SMART SM00861 287 450 1.0E-52 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 Gene3D G3DSA:3.40.50.920 463 593 4.0E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 SUPERFAMILY SSF52922 459 591 4.71E-29 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS09235 3e71e5793a4c57efc56aacdb9f8e32a5 595 SUPERFAMILY SSF52518 286 471 2.36E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 SUPERFAMILY SSF46785 3 84 4.73E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 SUPERFAMILY SSF53850 89 275 3.26E-25 T 28-03-2018 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 3.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 3.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 3.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 Gene3D G3DSA:3.40.190.10 170 241 4.7E-4 T 28-03-2018 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 56 4.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 Gene3D G3DSA:3.40.190.10 86 169 1.3E-13 T 28-03-2018 CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 Gene3D G3DSA:1.10.10.10 1 83 3.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04630 3585f1a6fc9cd836f8fb1fb63d617254 280 Pfam PF03466 LysR substrate binding domain 89 271 4.8E-21 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS06570 58578c04e59220a08fbd806384ac881b 215 Pfam PF02397 Bacterial sugar transferase 30 209 4.3E-64 T 28-03-2018 IPR003362 Bacterial sugar transferase CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 300 2.3E-25 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 Gene3D G3DSA:3.90.78.10 219 306 4.9E-23 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 307 86.28 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 Gene3D G3DSA:3.30.465.10 90 218 3.6E-35 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 24 302 2.6E-67 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 SUPERFAMILY SSF56194 201 303 1.44E-33 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 SUPERFAMILY SSF56176 5 197 1.07E-42 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 Pfam PF01565 FAD binding domain 37 165 3.5E-25 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CPF12_RS12075 a4a8938da474fddce56625f3deb7d94c 307 Gene3D G3DSA:3.30.43.10 12 86 6.4E-22 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CPF12_RS09680 d6958d9622eaa6756350bcc7812717bc 89 Hamap MF_01507 UPF0297 protein . 1 85 25.924 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CPF12_RS09680 d6958d9622eaa6756350bcc7812717bc 89 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 1.4E-33 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CPF12_RS09680 d6958d9622eaa6756350bcc7812717bc 89 PIRSF PIRSF037258 1 88 2.0E-39 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CPF12_RS01480 962c89dc39923e13f4ca5501619ab8e7 275 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 5 274 21.514 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CPF12_RS01480 962c89dc39923e13f4ca5501619ab8e7 275 Pfam PF01256 Carbohydrate kinase 29 266 4.5E-51 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CPF12_RS01480 962c89dc39923e13f4ca5501619ab8e7 275 SUPERFAMILY SSF53613 7 270 1.12E-58 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS01480 962c89dc39923e13f4ca5501619ab8e7 275 Gene3D G3DSA:3.40.1190.20 2 274 1.1E-38 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS01480 962c89dc39923e13f4ca5501619ab8e7 275 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 8 267 1.6E-52 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CPF12_RS09755 e0d4c835f17f2950acdd64e4fcfd1b4c 196 SUPERFAMILY SSF109604 4 178 3.14E-33 T 28-03-2018 CPF12_RS09755 e0d4c835f17f2950acdd64e4fcfd1b4c 196 Pfam PF01966 HD domain 18 130 3.7E-13 T 28-03-2018 IPR006674 HD domain CPF12_RS09755 e0d4c835f17f2950acdd64e4fcfd1b4c 196 TIGRFAM TIGR00277 HDIG: HDIG domain 16 94 4.6E-8 T 28-03-2018 IPR006675 HDIG domain CPF12_RS09755 e0d4c835f17f2950acdd64e4fcfd1b4c 196 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 2.8E-59 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CPF12_RS09755 e0d4c835f17f2950acdd64e4fcfd1b4c 196 SMART SM00471 14 141 3.4E-9 T 28-03-2018 IPR003607 HD/PDEase domain CPF12_RS09755 e0d4c835f17f2950acdd64e4fcfd1b4c 196 Gene3D G3DSA:1.10.3210.10 1 187 2.1E-27 T 28-03-2018 CPF12_RS01395 5574b30f51281ad927e351f7a89f7b4a 169 SUPERFAMILY SSF56300 1 165 1.35E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS01395 5574b30f51281ad927e351f7a89f7b4a 169 Gene3D G3DSA:3.60.21.10 1 167 4.4E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS01395 5574b30f51281ad927e351f7a89f7b4a 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 148 1.9E-26 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CPF12_RS01395 5574b30f51281ad927e351f7a89f7b4a 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 142 2.7E-28 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CPF12_RS11465 a69987dd985f5a70b842de9b26555844 250 Gene3D G3DSA:3.60.40.10 1 242 1.2E-47 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS11465 a69987dd985f5a70b842de9b26555844 250 SMART SM00331 7 243 6.5E-45 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS11465 a69987dd985f5a70b842de9b26555844 250 Pfam PF13672 Protein phosphatase 2C 12 215 7.9E-19 T 28-03-2018 CPF12_RS11465 a69987dd985f5a70b842de9b26555844 250 SUPERFAMILY SSF81606 2 241 4.05E-64 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS11465 a69987dd985f5a70b842de9b26555844 250 SMART SM00332 1 241 1.8E-35 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CPF12_RS02340 9ec546727af56d640fa95b5f8d33a132 155 SUPERFAMILY SSF55486 37 153 1.07E-13 T 28-03-2018 CPF12_RS02340 9ec546727af56d640fa95b5f8d33a132 155 Gene3D G3DSA:3.40.390.10 33 155 1.8E-11 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CPF12_RS02340 9ec546727af56d640fa95b5f8d33a132 155 Pfam PF00413 Matrixin 108 152 2.8E-6 T 28-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 SMART SM01121 227 538 5.1E-160 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 Pfam PF13684 Dihydroxyacetone kinase family 227 538 9.7E-116 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 1 538 1.1E-196 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 Gene3D G3DSA:3.20.20.70 407 536 0.075 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 SUPERFAMILY SSF101473 2 190 2.49E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 Pfam PF02734 DAK2 domain 23 188 2.0E-38 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS11505 b2f940ecbc47a72fdf1ad77ab50e2207 538 SMART SM01120 23 189 6.7E-67 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS01830 19c297bfe04330657bb9b5f638baf874 148 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.646 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CPF12_RS01830 19c297bfe04330657bb9b5f638baf874 148 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 1.8E-56 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CPF12_RS01830 19c297bfe04330657bb9b5f638baf874 148 Gene3D G3DSA:3.50.80.10 1 145 4.7E-56 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CPF12_RS01830 19c297bfe04330657bb9b5f638baf874 148 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 1.2E-54 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CPF12_RS01830 19c297bfe04330657bb9b5f638baf874 148 SUPERFAMILY SSF69500 1 144 1.29E-55 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CPF12_RS12310 a53dd80dd3e703834fbfb59ed8aac9e7 422 Gene3D G3DSA:2.30.42.10 202 288 4.3E-17 T 28-03-2018 CPF12_RS12310 a53dd80dd3e703834fbfb59ed8aac9e7 422 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 420 3.6E-100 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CPF12_RS12310 a53dd80dd3e703834fbfb59ed8aac9e7 422 SUPERFAMILY SSF50156 174 269 2.37E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS12310 a53dd80dd3e703834fbfb59ed8aac9e7 422 Pfam PF13180 PDZ domain 206 267 9.9E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS12310 a53dd80dd3e703834fbfb59ed8aac9e7 422 Pfam PF02163 Peptidase family M50 6 407 8.9E-79 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 PIRSF PIRSF000103 1 289 2.0E-73 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 160 1.3E-48 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 SUPERFAMILY SSF51735 2 163 8.14E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 SUPERFAMILY SSF48179 163 285 1.59E-35 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 1.2E-32 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 Gene3D G3DSA:3.40.50.720 1 163 1.2E-33 T 28-03-2018 CPF12_RS08580 28e435b532b343260ec390f1352f2630 289 Gene3D G3DSA:1.10.1040.10 164 289 8.2E-33 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 SUPERFAMILY SSF52540 6 256 2.0E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 SMART SM00382 35 235 3.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 299 7.3E-13 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 6.2E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 Gene3D G3DSA:3.40.50.300 3 336 4.8E-83 T 28-03-2018 CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 Pfam PF00005 ABC transporter 27 185 9.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03715 9cec1061f461170e24489c6c31418c31 351 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS08235 a89bf4ab0e12b976ce9a17ad879af6b3 276 Gene3D G3DSA:1.10.3100.10 8 131 3.0E-16 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS08235 a89bf4ab0e12b976ce9a17ad879af6b3 276 SMART SM00530 14 71 3.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS08235 a89bf4ab0e12b976ce9a17ad879af6b3 276 Pfam PF01381 Helix-turn-helix 15 71 2.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS08235 a89bf4ab0e12b976ce9a17ad879af6b3 276 SUPERFAMILY SSF47413 8 75 3.58E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 Gene3D G3DSA:3.40.50.300 460 695 4.0E-20 T 28-03-2018 CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 SUPERFAMILY SSF52540 532 708 2.0E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 801 25.145 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 SMART SM00487 262 461 1.8E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 Pfam PF00271 Helicase conserved C-terminal domain 569 660 5.2E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 Pfam PF00270 DEAD/DEAH box helicase 270 431 3.4E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 TIGRFAM TIGR00595 priA: primosomal protein N' 290 799 1.6E-213 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 Gene3D G3DSA:3.40.50.300 264 431 8.5E-29 T 28-03-2018 CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 SUPERFAMILY SSF52540 258 443 1.0E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11450 7c24a3fdebb366cdebfb00d2ca213c57 802 SMART SM00490 564 661 3.2E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CPF12_RS07670 15ddb1aeda5a2d2fe8f533cdc1858281 244 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07670 15ddb1aeda5a2d2fe8f533cdc1858281 244 SMART SM00382 30 223 4.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07670 15ddb1aeda5a2d2fe8f533cdc1858281 244 Pfam PF00005 ABC transporter 21 166 4.3E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07670 15ddb1aeda5a2d2fe8f533cdc1858281 244 SUPERFAMILY SSF52540 1 229 7.86E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07670 15ddb1aeda5a2d2fe8f533cdc1858281 244 Gene3D G3DSA:3.40.50.300 1 241 8.8E-66 T 28-03-2018 CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 31 280 2.4E-103 T 28-03-2018 IPR023705 Nucleoid occlusion protein CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 SUPERFAMILY SSF110849 22 125 1.36E-29 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 Pfam PF02195 ParB-like nuclease domain 33 121 1.5E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 SMART SM00470 32 122 6.8E-33 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 Gene3D G3DSA:3.90.1530.10 19 122 1.3E-34 T 28-03-2018 CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 29 207 7.6E-56 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 SUPERFAMILY SSF109709 116 222 2.88E-31 T 28-03-2018 CPF12_RS05460 25e4eaa4791f4bee51cfea831b4f6a46 282 Gene3D G3DSA:1.10.10.730 123 170 1.9E-19 T 28-03-2018 CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 Gene3D G3DSA:3.40.50.720 208 336 2.6E-12 T 28-03-2018 CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 Gene3D G3DSA:3.40.50.720 27 168 4.9E-23 T 28-03-2018 CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 36 145 6.0E-14 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 207 328 7.3E-20 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 SMART SM01003 30 158 9.0E-9 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 Gene3D G3DSA:3.40.50.720 169 207 3.0E-4 T 28-03-2018 CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 SUPERFAMILY SSF52283 28 191 2.72E-22 T 28-03-2018 CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 SUPERFAMILY SSF51735 173 291 6.36E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS04445 b32c12bc81f28b844895ea8bc452fcc6 355 SMART SM01002 166 285 4.8E-22 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CPF12_RS08350 5c1eb9a9dc3e2e0f5397a9b270500940 417 Gene3D G3DSA:1.20.1250.20 14 197 9.2E-26 T 28-03-2018 CPF12_RS08350 5c1eb9a9dc3e2e0f5397a9b270500940 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CPF12_RS08350 5c1eb9a9dc3e2e0f5397a9b270500940 417 SUPERFAMILY SSF103473 13 412 2.35E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS08350 5c1eb9a9dc3e2e0f5397a9b270500940 417 Pfam PF07690 Major Facilitator Superfamily 20 252 3.2E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS08350 5c1eb9a9dc3e2e0f5397a9b270500940 417 Pfam PF07690 Major Facilitator Superfamily 259 408 2.5E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS08350 5c1eb9a9dc3e2e0f5397a9b270500940 417 Gene3D G3DSA:1.20.1250.20 208 417 1.9E-21 T 28-03-2018 CPF12_RS02075 468656c70f8615a96bc5e98db75781eb 352 SUPERFAMILY SSF54211 230 344 2.66E-20 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS02075 468656c70f8615a96bc5e98db75781eb 352 SUPERFAMILY SSF50156 129 217 8.63E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS02075 468656c70f8615a96bc5e98db75781eb 352 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 234 306 7.6E-8 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CPF12_RS02075 468656c70f8615a96bc5e98db75781eb 352 Gene3D G3DSA:3.30.230.10 28 352 2.8E-37 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS02075 468656c70f8615a96bc5e98db75781eb 352 Pfam PF13180 PDZ domain 127 190 1.3E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 Pfam PF02603 HPr Serine kinase N terminus 6 129 1.5E-35 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 5 308 40.53 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 Pfam PF07475 HPr Serine kinase C-terminal domain 132 299 1.4E-73 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 Gene3D G3DSA:3.40.50.300 135 309 1.2E-43 T 28-03-2018 CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 SUPERFAMILY SSF75138 5 132 6.93E-37 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 Gene3D G3DSA:3.40.1390.20 5 134 2.3E-39 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 SUPERFAMILY SSF53795 135 300 1.04E-40 T 28-03-2018 CPF12_RS06770 d2b5f5375a0d9e16df07d9b2969fd2d4 312 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 304 1.3E-114 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CPF12_RS06640 4b68f60dcb22939c46d71aaeaab86215 179 Gene3D G3DSA:3.30.160.100 1 103 3.9E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CPF12_RS06640 4b68f60dcb22939c46d71aaeaab86215 179 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 179 24.21 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CPF12_RS06640 4b68f60dcb22939c46d71aaeaab86215 179 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 121 175 9.0E-26 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CPF12_RS06640 4b68f60dcb22939c46d71aaeaab86215 179 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 96 3.9E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CPF12_RS06640 4b68f60dcb22939c46d71aaeaab86215 179 SUPERFAMILY SSF69754 3 104 4.97E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CPF12_RS06640 4b68f60dcb22939c46d71aaeaab86215 179 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 3 101 2.0E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 PRINTS PR00474 Glutamate 5-kinase family signature 156 183 3.6E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 3.6E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 3.6E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 3.6E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 3.6E-51 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 265 8.3E-90 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 265 36.134 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 Gene3D G3DSA:3.40.1160.10 1 266 1.2E-57 T 28-03-2018 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 SUPERFAMILY SSF53633 9 265 1.17E-68 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 Pfam PF00696 Amino acid kinase family 9 243 8.5E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 PIRSF PIRSF000729 4 266 2.2E-94 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CPF12_RS08190 788dd60b56c07aa569a6583eb1ada361 266 ProSitePatterns PS00902 Glutamate 5-kinase signature. 215 232 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 SUPERFAMILY SSF53155 5 83 4.71E-13 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 Gene3D G3DSA:1.10.10.10 72 166 6.3E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 134 140 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 79 163 2.5E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 164 1.2E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 SUPERFAMILY SSF46767 79 165 5.62E-26 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CPF12_RS05300 6182621c74ab4779846e0a5ac7aa1333 167 Gene3D G3DSA:3.30.160.70 1 69 5.2E-14 T 28-03-2018 CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 SUPERFAMILY SSF51735 102 265 7.64E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 Gene3D G3DSA:3.40.50.720 113 272 3.5E-27 T 28-03-2018 CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 267 1.0E-79 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 Gene3D G3DSA:3.40.50.10860 1 112 1.5E-39 T 28-03-2018 CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 267 32.296 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 SUPERFAMILY SSF53223 2 101 3.86E-31 T 28-03-2018 CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 120 189 7.4E-11 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CPF12_RS09740 7c5ed1eacac0ccc4c698104e6769f75c 273 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 9.0E-28 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CPF12_RS05200 b040cfa248cc5559e3753eee8ed9c129 234 Gene3D G3DSA:3.20.20.70 108 205 6.9E-15 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS05200 b040cfa248cc5559e3753eee8ed9c129 234 Gene3D G3DSA:3.20.20.400 15 107 0.021 T 28-03-2018 CPF12_RS05200 b040cfa248cc5559e3753eee8ed9c129 234 SUPERFAMILY SSF51412 67 218 3.39E-14 T 28-03-2018 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 295 1.6E-106 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 213 3.6E-79 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 SUPERFAMILY SSF53850 4 219 7.39E-80 T 28-03-2018 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 SUPERFAMILY SSF54782 220 305 3.27E-20 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 PRINTS PR00151 Porphobilinogen deaminase signature 44 64 7.4E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 7.4E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 PRINTS PR00151 Porphobilinogen deaminase signature 75 94 7.4E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 7.4E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 7.4E-43 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 Gene3D G3DSA:3.40.190.10 1 105 1.8E-40 T 28-03-2018 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 Gene3D G3DSA:3.40.190.10 106 199 2.9E-38 T 28-03-2018 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 5.3E-16 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 PIRSF PIRSF001438 1 308 5.9E-116 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 295 37.887 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12465 3af6ab5b7faee91922bb79777d6016d1 308 Gene3D G3DSA:3.30.160.40 220 304 2.3E-18 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS01585 8d943d38dd4a6cc4885b3c4e2b3eb7e2 339 Pfam PF00482 Type II secretion system (T2SS), protein F 16 135 1.3E-9 T 28-03-2018 IPR018076 Type II secretion system F domain CPF12_RS01585 8d943d38dd4a6cc4885b3c4e2b3eb7e2 339 Pfam PF00482 Type II secretion system (T2SS), protein F 210 331 1.7E-21 T 28-03-2018 IPR018076 Type II secretion system F domain CPF12_RS01585 8d943d38dd4a6cc4885b3c4e2b3eb7e2 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 320 339 2.6E-11 T 28-03-2018 IPR003004 GspF/PilC family CPF12_RS01585 8d943d38dd4a6cc4885b3c4e2b3eb7e2 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 107 135 2.6E-11 T 28-03-2018 IPR003004 GspF/PilC family CPF12_RS01585 8d943d38dd4a6cc4885b3c4e2b3eb7e2 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 304 318 2.6E-11 T 28-03-2018 IPR003004 GspF/PilC family CPF12_RS01585 8d943d38dd4a6cc4885b3c4e2b3eb7e2 339 PRINTS PR00812 Bacterial general secretion pathway protein F signature 12 24 2.6E-11 T 28-03-2018 IPR003004 GspF/PilC family CPF12_RS03240 23312836d9149282c4ccc8fe1abf87ef 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 416 1.2E-44 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS03240 23312836d9149282c4ccc8fe1abf87ef 446 Pfam PF01554 MatE 22 182 6.0E-27 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS03240 23312836d9149282c4ccc8fe1abf87ef 446 Pfam PF01554 MatE 242 402 2.6E-16 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS03240 23312836d9149282c4ccc8fe1abf87ef 446 PIRSF PIRSF006603 1 445 2.4E-62 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS00345 85fdccbe604bf73a111b191c2302d3ce 359 Gene3D G3DSA:3.30.420.10 14 198 8.1E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS00345 85fdccbe604bf73a111b191c2302d3ce 359 Pfam PF00929 Exonuclease 35 188 2.5E-33 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CPF12_RS00345 85fdccbe604bf73a111b191c2302d3ce 359 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 33 194 1.4E-34 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS00345 85fdccbe604bf73a111b191c2302d3ce 359 SUPERFAMILY SSF53098 31 224 2.94E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS00345 85fdccbe604bf73a111b191c2302d3ce 359 SMART SM00479 33 194 1.7E-44 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CPF12_RS00310 54839c476d1935f419510af1df6ce50e 734 Gene3D G3DSA:2.70.98.10 6 302 2.1E-61 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CPF12_RS00310 54839c476d1935f419510af1df6ce50e 734 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 17 713 5.3E-146 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CPF12_RS00310 54839c476d1935f419510af1df6ce50e 734 Pfam PF07971 Glycosyl hydrolase family 92 221 713 5.0E-144 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CPF12_RS00310 54839c476d1935f419510af1df6ce50e 734 SUPERFAMILY SSF48208 249 692 6.57E-24 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CPF12_RS00310 54839c476d1935f419510af1df6ce50e 734 Gene3D G3DSA:1.20.1050.60 327 420 3.0E-22 T 28-03-2018 CPF12_RS00310 54839c476d1935f419510af1df6ce50e 734 Gene3D G3DSA:3.30.2080.10 562 726 3.1E-55 T 28-03-2018 CPF12_RS11600 5fce277706b7350acf517d6074f33859 251 Gene3D G3DSA:1.20.1290.10 2 248 8.6E-43 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CPF12_RS11600 5fce277706b7350acf517d6074f33859 251 SUPERFAMILY SSF69118 7 247 1.6E-58 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CPF12_RS11600 5fce277706b7350acf517d6074f33859 251 Pfam PF02627 Carboxymuconolactone decarboxylase family 165 246 9.2E-11 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CPF12_RS11600 5fce277706b7350acf517d6074f33859 251 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 101 1.4E-5 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CPF12_RS08800 b65c5e15626992227bb99226b6d83f36 887 Gene3D G3DSA:2.60.40.1220 341 508 0.52 T 28-03-2018 CPF12_RS08800 b65c5e15626992227bb99226b6d83f36 887 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 855 887 2.6E-8 T 28-03-2018 CPF12_RS08800 b65c5e15626992227bb99226b6d83f36 887 Pfam PF00746 LPXTG cell wall anchor motif 848 886 2.7E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 Gene3D G3DSA:3.90.770.10 1 116 5.7E-22 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 SUPERFAMILY SSF56542 2 113 7.59E-99 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 SUPERFAMILY SSF56542 224 422 7.59E-99 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 3 381 4.0E-101 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 10 380 6.4E-111 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 SUPERFAMILY SSF55035 106 214 1.36E-29 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 Gene3D G3DSA:3.90.770.10 214 385 8.4E-34 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 Gene3D G3DSA:3.30.70.420 117 213 1.3E-30 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS01555 a303f2386bd35bc3df21522802718d8e 423 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 366 379 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CPF12_RS08160 7fcebd13b5d52dc9845a762762cc4420 242 Pfam PF14568 SMI1-KNR4 cell-wall 16 128 9.5E-8 T 28-03-2018 CPF12_RS08160 7fcebd13b5d52dc9845a762762cc4420 242 Gene3D G3DSA:3.40.1580.10 15 151 1.5E-5 T 28-03-2018 CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 3.0E-72 T 28-03-2018 CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 1.3E-4 T 28-03-2018 CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 246 7.0E-100 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 SUPERFAMILY SSF51735 5 248 1.03E-89 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 Gene3D G3DSA:3.40.50.720 41 248 2.2E-71 T 28-03-2018 CPF12_RS11530 246fcab1aa79235aed9e3332fce7c7c7 248 Gene3D G3DSA:3.40.50.720 1 40 1.0E-8 T 28-03-2018 CPF12_RS08180 64e69f15e6505129f04ff9eef56643df 350 Pfam PF01594 AI-2E family transporter 15 329 3.1E-43 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CPF12_RS04830 c91ca07a36af2f04afbe0a02c73399a8 216 Pfam PF17118 Domain of unknown function (DUF5105) 22 213 3.7E-17 T 28-03-2018 IPR031343 Domain of unknown function DUF5105 CPF12_RS04830 c91ca07a36af2f04afbe0a02c73399a8 216 Gene3D G3DSA:3.40.190.10 1 211 1.3E-5 T 28-03-2018 CPF12_RS04225 44de7c683786518aab6ddbe057d167b1 181 Pfam PF13238 AAA domain 4 129 7.2E-7 T 28-03-2018 CPF12_RS04225 44de7c683786518aab6ddbe057d167b1 181 Gene3D G3DSA:3.40.50.300 1 180 3.7E-18 T 28-03-2018 CPF12_RS04225 44de7c683786518aab6ddbe057d167b1 181 SUPERFAMILY SSF52540 1 167 8.58E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04145 39f1a0cd9a429e7a0b0b532fa13620c7 304 Pfam PF00248 Aldo/keto reductase family 16 295 4.4E-56 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS04145 39f1a0cd9a429e7a0b0b532fa13620c7 304 Gene3D G3DSA:3.20.20.100 1 302 9.4E-74 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS04145 39f1a0cd9a429e7a0b0b532fa13620c7 304 SUPERFAMILY SSF51430 1 299 8.64E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 436 455 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 SUPERFAMILY SSF52467 205 312 3.27E-6 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 SUPERFAMILY SSF52518 380 555 3.57E-25 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 Gene3D G3DSA:3.40.50.1220 188 344 4.9E-9 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 411 542 1.9E-16 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 SUPERFAMILY SSF52518 4 181 1.55E-14 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 Gene3D G3DSA:3.40.50.970 1 187 2.0E-13 T 28-03-2018 CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 178 4.9E-11 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS05310 edd0b64cde240cb9afe6d3adaf2acfd6 566 Gene3D G3DSA:3.40.50.970 372 555 3.7E-20 T 28-03-2018 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 Pfam PF03466 LysR substrate binding domain 90 291 1.4E-40 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 SUPERFAMILY SSF46785 2 86 4.14E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 Gene3D G3DSA:1.10.10.10 1 83 5.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 SUPERFAMILY SSF53850 90 294 1.63E-37 T 28-03-2018 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 Gene3D G3DSA:3.40.190.10 181 267 1.8E-19 T 28-03-2018 CPF12_RS08990 cb543953ccfc1688c70d5ab3b2b04283 301 Gene3D G3DSA:3.40.190.10 90 180 1.6E-19 T 28-03-2018 CPF12_RS05235 f5203aa85026c3181e5e1951de8a887d 475 Pfam PF05043 Mga helix-turn-helix domain 72 155 1.7E-16 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS05235 f5203aa85026c3181e5e1951de8a887d 475 Pfam PF08270 M protein trans-acting positive regulator (MGA) PRD domain 199 373 8.4E-5 T 28-03-2018 IPR013236 M protein trans-acting positive regulator (MGA), PRD domain CPF12_RS05235 f5203aa85026c3181e5e1951de8a887d 475 Gene3D G3DSA:1.10.10.10 2 69 2.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05235 f5203aa85026c3181e5e1951de8a887d 475 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 8 49 5.9E-8 T 28-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain CPF12_RS05235 f5203aa85026c3181e5e1951de8a887d 475 Gene3D G3DSA:1.10.10.10 72 145 7.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02620 13e1757a5eb242e07ad6e77cbbb67e68 172 SUPERFAMILY SSF55729 4 163 5.74E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS02620 13e1757a5eb242e07ad6e77cbbb67e68 172 Pfam PF00583 Acetyltransferase (GNAT) family 49 146 7.3E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS02620 13e1757a5eb242e07ad6e77cbbb67e68 172 Gene3D G3DSA:3.40.630.30 3 172 4.2E-28 T 28-03-2018 CPF12_RS08920 99eee2f0725d1a2b961b877ad899e5bb 147 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 90 107 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CPF12_RS08920 99eee2f0725d1a2b961b877ad899e5bb 147 SUPERFAMILY SSF55781 5 146 9.38E-42 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS08920 99eee2f0725d1a2b961b877ad899e5bb 147 Pfam PF13185 GAF domain 36 145 1.1E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CPF12_RS08920 99eee2f0725d1a2b961b877ad899e5bb 147 Gene3D G3DSA:3.30.450.40 2 147 6.7E-24 T 28-03-2018 IPR029016 GAF domain-like CPF12_RS11735 623de19581931e9749a41c8f37889a76 148 Pfam PF07681 DoxX 11 104 2.6E-7 T 28-03-2018 IPR032808 DoxX family CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 Hamap MF_00303 Trigger factor [tig]. 1 426 22.056 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 237 1.2E-15 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 PIRSF PIRSF003095 1 426 2.1E-126 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 SUPERFAMILY SSF54534 90 242 4.52E-36 T 28-03-2018 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 Gene3D G3DSA:3.30.70.1050 1 119 5.2E-33 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 TIGRFAM TIGR00115 tig: trigger factor 12 419 1.4E-129 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 Gene3D G3DSA:1.10.3120.10 212 398 2.2E-50 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 1.1E-40 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 SUPERFAMILY SSF109998 249 423 1.47E-37 T 28-03-2018 IPR027304 Trigger factor/SurA domain CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 SUPERFAMILY SSF102735 1 132 3.14E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CPF12_RS01145 b86be8cd0fcde848f4a873faa9fc58a1 426 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 420 4.4E-41 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 SUPERFAMILY SSF46785 2 62 2.33E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Pfam PF08279 HTH domain 7 60 9.5E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 323 32.874 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Gene3D G3DSA:3.30.930.10 60 277 4.9E-64 T 28-03-2018 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Pfam PF03099 Biotin/lipoate A/B protein ligase family 92 214 1.2E-16 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Gene3D G3DSA:1.10.10.10 1 59 4.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 SUPERFAMILY SSF55681 72 275 2.15E-61 T 28-03-2018 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Gene3D G3DSA:2.30.30.100 278 321 2.1E-10 T 28-03-2018 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 322 2.8E-64 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CPF12_RS10295 7275fe63c5e55c8500cf3b816d93d323 323 Pfam PF02237 Biotin protein ligase C terminal domain 279 322 2.2E-9 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CPF12_RS11490 248ee3843d8218638c3f04db4bd59a75 545 Gene3D G3DSA:3.40.50.300 308 531 7.9E-18 T 28-03-2018 CPF12_RS11490 248ee3843d8218638c3f04db4bd59a75 545 SUPERFAMILY SSF52540 308 528 3.7E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11490 248ee3843d8218638c3f04db4bd59a75 545 SMART SM00534 340 526 2.1E-11 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11490 248ee3843d8218638c3f04db4bd59a75 545 Gene3D G3DSA:1.10.1420.10 62 305 2.4E-6 T 28-03-2018 CPF12_RS11490 248ee3843d8218638c3f04db4bd59a75 545 Pfam PF00488 MutS domain V 343 526 6.5E-27 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CPF12_RS11800 3f5825895cfbed7be0ea7a83091a30e9 257 Hamap MF_00052_B Ribonuclease HII [rnhB]. 74 253 34.981 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CPF12_RS11800 3f5825895cfbed7be0ea7a83091a30e9 257 Gene3D G3DSA:3.30.420.10 50 257 2.7E-67 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS11800 3f5825895cfbed7be0ea7a83091a30e9 257 SUPERFAMILY SSF53098 63 257 8.65E-65 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS11800 3f5825895cfbed7be0ea7a83091a30e9 257 Pfam PF01351 Ribonuclease HII 76 252 3.5E-40 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 SUPERFAMILY SSF54211 5 185 2.43E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 Pfam PF08544 GHMP kinases C terminal 224 298 1.8E-14 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 SUPERFAMILY SSF55060 169 308 1.3E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 Gene3D G3DSA:3.30.230.10 2 52 1.8E-4 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 Gene3D G3DSA:3.30.230.10 53 180 8.0E-22 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 280 1.7E-73 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 Pfam PF00288 GHMP kinases N terminal domain 87 149 4.2E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 PRINTS PR00959 Mevalonate kinase family signature 265 282 4.7E-18 T 28-03-2018 CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 PRINTS PR00959 Mevalonate kinase family signature 7 31 4.7E-18 T 28-03-2018 CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 PRINTS PR00959 Mevalonate kinase family signature 91 113 4.7E-18 T 28-03-2018 CPF12_RS05075 cf716596ebe2c6150b1cada46250721d 309 Gene3D G3DSA:3.30.70.890 181 309 7.6E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS04265 2fcaefc816ffa012cec92d28f0ec7e3e 172 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 8.4E-8 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 171 199 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 Gene3D G3DSA:3.40.50.20 9 88 5.1E-7 T 28-03-2018 CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 163 196 1.3E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 126 161 1.4E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 SUPERFAMILY SSF51161 5 213 3.6E-44 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 11 211 6.3E-61 T 28-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CPF12_RS08905 4f2f81b7f126eb988f79ceff9c2e958b 213 Gene3D G3DSA:2.160.10.10 89 213 1.5E-31 T 28-03-2018 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 Pfam PF02926 THUMP domain 33 124 2.5E-7 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 302 308 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 197 208 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 Gene3D G3DSA:3.40.50.150 162 384 4.5E-28 T 28-03-2018 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 SMART SM00981 58 156 1.2E-4 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 Pfam PF01170 Putative RNA methylase family UPF0020 164 369 6.5E-59 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 SUPERFAMILY SSF53335 145 219 3.33E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS10435 f9be45e38e42212ca300f05cb2a82df2 384 SUPERFAMILY SSF53335 256 362 3.33E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 SUPERFAMILY SSF46785 89 160 4.05E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 SUPERFAMILY SSF46785 2 82 3.27E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 Gene3D G3DSA:1.10.10.10 86 177 1.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 185 35.161 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 Pfam PF04079 Segregation and condensation complex subunit ScpB 8 168 1.5E-56 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 PIRSF PIRSF019345 1 207 1.1E-55 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 Gene3D G3DSA:1.10.10.10 2 85 2.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09405 254add65827eeb2958d8530bdbe8c85c 208 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 189 1.7E-54 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 SUPERFAMILY SSF53623 97 331 2.75E-73 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 SUPERFAMILY SSF63418 1 97 9.42E-26 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 104 128 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Gene3D G3DSA:3.90.190.20 337 488 1.1E-51 T 28-03-2018 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 416 1.5E-24 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Gene3D G3DSA:3.40.1190.10 97 336 4.2E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 36.396 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Gene3D G3DSA:3.40.1390.10 1 96 4.0E-28 T 28-03-2018 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Pfam PF01225 Mur ligase family, catalytic domain 22 93 3.3E-13 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 SUPERFAMILY SSF53244 332 486 9.55E-51 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 19 484 3.4E-170 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CPF12_RS02030 41fa4f555323c9e9312a07b3f44f9711 488 Pfam PF08245 Mur ligase middle domain 106 311 1.3E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 Gene3D G3DSA:3.40.50.450 1 196 9.9E-78 T 28-03-2018 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 SUPERFAMILY SSF53784 1 312 5.76E-115 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 Gene3D G3DSA:3.40.50.450 197 300 3.1E-16 T 28-03-2018 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.8E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 6.1E-127 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 Pfam PF00365 Phosphofructokinase 3 275 7.1E-110 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 47.527 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CPF12_RS08440 83920ec53cc36adf51d2cff5633df8bc 319 PIRSF PIRSF000532 1 319 3.2E-122 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CPF12_RS08840 a80c3eeb31a7cb76bb605140c44cec0f 158 Gene3D G3DSA:2.60.40.1240 42 158 2.8E-8 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 Pfam PF01545 Cation efflux family 9 202 1.6E-49 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 285 4.8E-72 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 Gene3D G3DSA:1.20.1510.10 4 201 8.2E-47 T 28-03-2018 CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 Pfam PF16916 Dimerisation domain of Zinc Transporter 209 284 1.1E-21 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 SUPERFAMILY SSF161111 3 203 4.45E-57 T 28-03-2018 CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 SUPERFAMILY SSF160240 213 284 7.32E-19 T 28-03-2018 CPF12_RS05770 40d230f4d33a5ee0a0bd98c2c87af16c 295 Gene3D G3DSA:3.30.70.1350 202 291 2.5E-20 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CPF12_RS01580 00ae9984671f1841ed1080f8235e88aa 320 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 188 202 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CPF12_RS01580 00ae9984671f1841ed1080f8235e88aa 320 SUPERFAMILY SSF52540 2 284 7.32E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01580 00ae9984671f1841ed1080f8235e88aa 320 Gene3D G3DSA:3.30.450.90 1 95 3.5E-18 T 28-03-2018 CPF12_RS01580 00ae9984671f1841ed1080f8235e88aa 320 Gene3D G3DSA:3.40.50.300 106 269 3.6E-23 T 28-03-2018 CPF12_RS01580 00ae9984671f1841ed1080f8235e88aa 320 Pfam PF00437 Type II/IV secretion system protein 4 258 3.9E-53 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CPF12_RS10345 22c794d495cb3d3aa6e6cd4a395a34ea 244 Gene3D G3DSA:1.10.10.10 16 129 5.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10345 22c794d495cb3d3aa6e6cd4a395a34ea 244 SUPERFAMILY SSF158499 130 195 3.01E-18 T 28-03-2018 IPR006343 DnaD domain CPF12_RS10345 22c794d495cb3d3aa6e6cd4a395a34ea 244 Pfam PF07261 Replication initiation and membrane attachment 131 202 1.5E-22 T 28-03-2018 IPR006343 DnaD domain CPF12_RS10345 22c794d495cb3d3aa6e6cd4a395a34ea 244 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 201 1.7E-23 T 28-03-2018 IPR006343 DnaD domain CPF12_RS10345 22c794d495cb3d3aa6e6cd4a395a34ea 244 Gene3D G3DSA:1.10.10.630 130 201 4.5E-23 T 28-03-2018 IPR034829 DnaD-like domain CPF12_RS12030 0e6389cfbf8b6dc20405e889686612ad 102 Gene3D G3DSA:3.30.300.30 1 87 1.4E-14 T 28-03-2018 CPF12_RS12030 0e6389cfbf8b6dc20405e889686612ad 102 SUPERFAMILY SSF56801 2 99 3.14E-12 T 28-03-2018 CPF12_RS12030 0e6389cfbf8b6dc20405e889686612ad 102 Pfam PF13193 AMP-binding enzyme C-terminal domain 3 75 2.4E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CPF12_RS00170 65764262e6602d676d005719f4154230 204 PIRSF PIRSF034981 4 203 1.7E-17 T 28-03-2018 IPR013372 Ethanolamine utilization, putative CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 259 277 1.2E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 1.2E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 1.2E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.2E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 SUPERFAMILY SSF51905 1 292 7.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 Gene3D G3DSA:3.50.50.60 1 130 1.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.5E-10 T 28-03-2018 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.5E-10 T 28-03-2018 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 271 2.5E-10 T 28-03-2018 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 Gene3D G3DSA:3.50.50.60 141 303 9.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03130 a031ca4220691a3ca9a83e26f32af1f1 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 271 7.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 SUPERFAMILY SSF51445 28 357 1.47E-85 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 Gene3D G3DSA:3.20.20.80 13 365 1.5E-89 T 28-03-2018 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 SMART SM00812 21 395 2.6E-77 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 PRINTS PR00741 Glycosyl hydrolase family 29 signature 307 328 2.1E-16 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 PRINTS PR00741 Glycosyl hydrolase family 29 signature 109 125 2.1E-16 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 PRINTS PR00741 Glycosyl hydrolase family 29 signature 340 362 2.1E-16 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 PIRSF PIRSF001092 2 434 7.8E-109 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CPF12_RS07635 ec853ac8d12b7a31c3086810d8d33e16 437 Pfam PF01120 Alpha-L-fucosidase 11 354 3.1E-83 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 424 2.0E-163 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 Gene3D G3DSA:3.40.50.1980 224 369 1.0E-67 T 28-03-2018 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PIRSF PIRSF000099 1 428 2.9E-167 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 425 42.234 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 Gene3D G3DSA:3.40.50.1980 26 223 2.0E-85 T 28-03-2018 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 SUPERFAMILY SSF53720 27 425 1.41E-81 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 Pfam PF00815 Histidinol dehydrogenase 23 425 1.0E-169 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 359 377 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 318 343 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS00105 beb45cc9aff734526225c77b304f8b96 428 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 6.3E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CPF12_RS12015 09cfdc955fe8ec2348adcc05e19b1d3a 303 Gene3D G3DSA:3.40.50.1820 7 301 3.3E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS12015 09cfdc955fe8ec2348adcc05e19b1d3a 303 Pfam PF07859 alpha/beta hydrolase fold 81 277 2.4E-36 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CPF12_RS12015 09cfdc955fe8ec2348adcc05e19b1d3a 303 SUPERFAMILY SSF53474 48 294 2.3E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS07560 5458eb2caf82a1d76992e2f0c69eb4fe 104 SMART SM00530 3 58 5.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS07560 5458eb2caf82a1d76992e2f0c69eb4fe 104 Pfam PF01381 Helix-turn-helix 4 58 3.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS07560 5458eb2caf82a1d76992e2f0c69eb4fe 104 SUPERFAMILY SSF47413 2 64 2.95E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS07560 5458eb2caf82a1d76992e2f0c69eb4fe 104 Gene3D G3DSA:1.10.260.40 1 104 1.1E-20 T 28-03-2018 CPF12_RS12240 a44e2ba46561c721813226d6f5a91324 516 Pfam PF08857 Putative ParB-like nuclease 37 252 4.9E-33 T 28-03-2018 IPR014956 Putative ParB-like nuclease CPF12_RS12240 a44e2ba46561c721813226d6f5a91324 516 Gene3D G3DSA:1.10.8.10 220 282 4.9E-10 T 28-03-2018 CPF12_RS12240 a44e2ba46561c721813226d6f5a91324 516 SUPERFAMILY SSF110849 124 281 5.07E-36 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS12240 a44e2ba46561c721813226d6f5a91324 516 SUPERFAMILY SSF110849 33 77 5.07E-36 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CPF12_RS12240 a44e2ba46561c721813226d6f5a91324 516 Gene3D G3DSA:3.90.1530.10 30 215 6.0E-31 T 28-03-2018 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 2.1E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 2.1E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 48 2.1E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 2.1E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 Pfam PF01022 Bacterial regulatory protein, arsR family 23 68 4.8E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 Gene3D G3DSA:1.10.10.10 1 99 3.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 SMART SM00418 16 94 5.1E-30 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS05090 99266ffb34a3bc2d057136c5ef35d5ce 99 SUPERFAMILY SSF46785 7 96 3.23E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09745 aaf22f79fe3aad8c7a0e9b77b6ee23d6 97 Gene3D G3DSA:3.30.110.60 1 97 1.1E-27 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CPF12_RS09745 aaf22f79fe3aad8c7a0e9b77b6ee23d6 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.2E-22 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CPF12_RS09745 aaf22f79fe3aad8c7a0e9b77b6ee23d6 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 2.7E-35 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CPF12_RS09745 aaf22f79fe3aad8c7a0e9b77b6ee23d6 97 SUPERFAMILY SSF75471 1 95 5.76E-31 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CPF12_RS09745 aaf22f79fe3aad8c7a0e9b77b6ee23d6 97 SMART SM01103 2 85 6.2E-41 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CPF12_RS09745 aaf22f79fe3aad8c7a0e9b77b6ee23d6 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 2.0E-28 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CPF12_RS01605 41edb6e2253db04820d3218adff50500 150 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 29 1.2E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CPF12_RS01605 41edb6e2253db04820d3218adff50500 150 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 1.6E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CPF12_RS01605 41edb6e2253db04820d3218adff50500 150 PIRSF PIRSF021292 5 144 2.6E-18 T 28-03-2018 IPR016785 ComG operon protein 4 GO:0030420 CPF12_RS06710 1d2f8b0f9ff330887e0646749d09a7d1 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06710 1d2f8b0f9ff330887e0646749d09a7d1 252 SUPERFAMILY SSF52540 4 241 1.47E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06710 1d2f8b0f9ff330887e0646749d09a7d1 252 Gene3D G3DSA:3.40.50.300 1 250 6.5E-62 T 28-03-2018 CPF12_RS06710 1d2f8b0f9ff330887e0646749d09a7d1 252 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 252 6.2E-122 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CPF12_RS06710 1d2f8b0f9ff330887e0646749d09a7d1 252 SMART SM00382 30 233 1.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06710 1d2f8b0f9ff330887e0646749d09a7d1 252 Pfam PF00005 ABC transporter 22 176 1.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10620 a2995b7564a5e4132c7215e770ffa204 77 PIRSF PIRSF037262 1 74 4.6E-32 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CPF12_RS10620 a2995b7564a5e4132c7215e770ffa204 77 Pfam PF06855 YozE SAM-like fold 4 69 3.0E-24 T 28-03-2018 IPR023089 YozE SAM-like domain CPF12_RS10620 a2995b7564a5e4132c7215e770ffa204 77 Hamap MF_01538 UPF0346 protein . 1 71 24.11 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CPF12_RS10620 a2995b7564a5e4132c7215e770ffa204 77 Gene3D G3DSA:1.10.150.260 3 71 9.0E-23 T 28-03-2018 IPR023089 YozE SAM-like domain CPF12_RS10620 a2995b7564a5e4132c7215e770ffa204 77 SUPERFAMILY SSF140652 3 72 9.29E-27 T 28-03-2018 IPR023089 YozE SAM-like domain CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 Pfam PF00825 Ribonuclease P 1 108 3.1E-29 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 111 4.3E-28 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 118 2.0E-27 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 113 17.725 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 Gene3D G3DSA:3.30.230.10 1 118 7.3E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05485 813cefbc5f911349078796df1ab39f5b 118 SUPERFAMILY SSF54211 1 115 2.78E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS08845 9abd92a148cbef794eff6cba5c9fbffc 469 SUPERFAMILY SSF51735 4 132 1.73E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08845 9abd92a148cbef794eff6cba5c9fbffc 469 SUPERFAMILY SSF51735 144 402 1.78E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS08845 9abd92a148cbef794eff6cba5c9fbffc 469 Gene3D G3DSA:3.40.50.720 140 466 2.9E-61 T 28-03-2018 CPF12_RS08845 9abd92a148cbef794eff6cba5c9fbffc 469 Gene3D G3DSA:3.40.50.720 2 128 6.8E-19 T 28-03-2018 CPF12_RS08845 9abd92a148cbef794eff6cba5c9fbffc 469 Pfam PF02719 Polysaccharide biosynthesis protein 147 423 3.0E-110 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 Pfam PF00698 Acyl transferase domain 6 289 2.6E-36 T 28-03-2018 IPR014043 Acyl transferase CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 Gene3D G3DSA:3.40.366.10 183 310 5.5E-27 T 28-03-2018 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 288 3.2E-99 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 Gene3D G3DSA:3.40.366.10 3 139 7.1E-40 T 28-03-2018 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 Gene3D G3DSA:3.30.70.250 140 182 9.2E-23 T 28-03-2018 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 PIRSF PIRSF000446 1 309 6.8E-104 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 SUPERFAMILY SSF55048 125 195 2.49E-15 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 311 4.6E-43 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 SUPERFAMILY SSF52151 4 121 1.28E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CPF12_RS11525 be079992940c46c9a9d98a42ce488d91 311 SUPERFAMILY SSF52151 188 307 1.28E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CPF12_RS06175 4dc9580f23d243558a134f07530a0f41 37 Pfam PF00444 Ribosomal protein L36 1 37 3.7E-20 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06175 4dc9580f23d243558a134f07530a0f41 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.906 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06175 4dc9580f23d243558a134f07530a0f41 37 SUPERFAMILY SSF57840 1 37 2.62E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06175 4dc9580f23d243558a134f07530a0f41 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06175 4dc9580f23d243558a134f07530a0f41 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 28-03-2018 CPF12_RS06175 4dc9580f23d243558a134f07530a0f41 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.8E-24 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS02995 c124ce6bfcdeadfd5052f83ed2e32f78 143 SUPERFAMILY SSF55729 4 143 6.69E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS02995 c124ce6bfcdeadfd5052f83ed2e32f78 143 Pfam PF13673 Acetyltransferase (GNAT) domain 42 143 2.9E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS02995 c124ce6bfcdeadfd5052f83ed2e32f78 143 Gene3D G3DSA:3.40.630.30 4 143 8.3E-31 T 28-03-2018 CPF12_RS00255 8fd67700570ea3f5e21bb20a909804d6 241 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 72 5.3E-16 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CPF12_RS00255 8fd67700570ea3f5e21bb20a909804d6 241 SUPERFAMILY SSF53697 82 231 4.84E-31 T 28-03-2018 CPF12_RS00255 8fd67700570ea3f5e21bb20a909804d6 241 Gene3D G3DSA:1.10.10.10 4 69 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00255 8fd67700570ea3f5e21bb20a909804d6 241 Gene3D G3DSA:3.40.50.10490 70 238 3.2E-26 T 28-03-2018 CPF12_RS00255 8fd67700570ea3f5e21bb20a909804d6 241 Pfam PF01380 SIS domain 110 213 1.5E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS00255 8fd67700570ea3f5e21bb20a909804d6 241 SUPERFAMILY SSF46689 5 73 4.12E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS00150 7cec8f847cdd54248510dcc32cf70b34 193 PIRSF PIRSF000709 1 187 3.3E-12 T 28-03-2018 CPF12_RS00150 7cec8f847cdd54248510dcc32cf70b34 193 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 186 5.0E-41 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS00150 7cec8f847cdd54248510dcc32cf70b34 193 SUPERFAMILY SSF53254 1 184 4.99E-47 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS00150 7cec8f847cdd54248510dcc32cf70b34 193 SMART SM00855 3 153 3.6E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS00150 7cec8f847cdd54248510dcc32cf70b34 193 Gene3D G3DSA:3.40.50.1240 1 190 3.1E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS00150 7cec8f847cdd54248510dcc32cf70b34 193 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 SUPERFAMILY SSF53067 6 174 8.81E-43 T 28-03-2018 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 Gene3D G3DSA:3.30.420.40 183 363 1.2E-39 T 28-03-2018 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 6 354 3.4E-106 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 SUPERFAMILY SSF53067 120 356 2.93E-41 T 28-03-2018 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 PRINTS PR00471 Acetate kinase family signature 276 289 2.9E-17 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 PRINTS PR00471 Acetate kinase family signature 344 356 2.9E-17 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 PRINTS PR00471 Acetate kinase family signature 299 315 2.9E-17 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 PRINTS PR00471 Acetate kinase family signature 182 203 2.9E-17 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 PRINTS PR00471 Acetate kinase family signature 7 18 2.9E-17 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 PIRSF PIRSF036458 3 358 6.4E-113 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 Hamap MF_00542 Probable butyrate kinase [buk]. 1 366 105.298 T 28-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 Pfam PF00871 Acetokinase family 7 335 1.5E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CPF12_RS09255 114554d2b7ce1be9cdef8852d4acbe2d 366 Gene3D G3DSA:3.30.420.40 4 182 7.5E-37 T 28-03-2018 CPF12_RS04075 eeb2d9e6f5b40bc08306b164e1e30144 603 Pfam PF02687 FtsX-like permease family 84 178 2.2E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS04075 eeb2d9e6f5b40bc08306b164e1e30144 603 PIRSF PIRSF018968 420 597 1.0E-17 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CPF12_RS04075 eeb2d9e6f5b40bc08306b164e1e30144 603 PIRSF PIRSF018968 1 443 1.6E-44 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 Gene3D G3DSA:3.20.20.80 6 481 2.2E-169 T 28-03-2018 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 374 382 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 2.9E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 382 2.9E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 2.9E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 2.9E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 PRINTS PR00131 Glycosyl hydrolase family 1 signature 292 306 2.9E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 SUPERFAMILY SSF51445 7 477 1.36E-167 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 Pfam PF00232 Glycosyl hydrolase family 1 8 475 2.5E-174 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS03335 345a2782560bc9c62964757e283212ac 481 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 PRINTS PR00045 Sigma-54 factor signature 155 172 1.6E-21 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 PRINTS PR00045 Sigma-54 factor signature 358 369 1.6E-21 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 PRINTS PR00045 Sigma-54 factor signature 342 354 1.6E-21 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 PRINTS PR00045 Sigma-54 factor signature 413 431 1.6E-21 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 437 8.0E-129 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 Gene3D G3DSA:1.10.10.10 285 380 1.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 PIRSF PIRSF000774 1 439 6.0E-118 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 9 51 4.2E-13 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 Pfam PF04963 Sigma-54 factor, core binding domain 86 269 3.2E-47 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 418 425 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CPF12_RS03935 cc634e59468f7beefeb95cdf42feb3f6 439 Pfam PF04552 Sigma-54, DNA binding domain 282 438 3.2E-52 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CPF12_RS07030 a473a99551e2310fcbf804625f6d872a 250 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 39 248 4.6E-62 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CPF12_RS07030 a473a99551e2310fcbf804625f6d872a 250 SUPERFAMILY SSF51569 3 249 1.72E-65 T 28-03-2018 CPF12_RS07030 a473a99551e2310fcbf804625f6d872a 250 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 28 249 29.017 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CPF12_RS07030 a473a99551e2310fcbf804625f6d872a 250 Gene3D G3DSA:3.20.20.70 2 250 3.4E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS07030 a473a99551e2310fcbf804625f6d872a 250 Pfam PF01487 Type I 3-dehydroquinase 20 248 3.2E-61 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CPF12_RS04220 bfb3c87cd0219d90fc469e98d5add19d 309 ProSitePatterns PS01095 Chitinases family 18 active site. 156 164 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CPF12_RS04220 bfb3c87cd0219d90fc469e98d5add19d 309 Pfam PF00704 Glycosyl hydrolases family 18 44 243 1.5E-18 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CPF12_RS04220 bfb3c87cd0219d90fc469e98d5add19d 309 SUPERFAMILY SSF51445 42 278 4.22E-55 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS04220 bfb3c87cd0219d90fc469e98d5add19d 309 Gene3D G3DSA:3.20.20.80 44 303 3.5E-35 T 28-03-2018 CPF12_RS04585 4e0d86b1deb93f68968e56d677b0d464 224 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS04585 4e0d86b1deb93f68968e56d677b0d464 224 Pfam PF00005 ABC transporter 23 170 3.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04585 4e0d86b1deb93f68968e56d677b0d464 224 Gene3D G3DSA:3.40.50.300 1 224 5.9E-55 T 28-03-2018 CPF12_RS04585 4e0d86b1deb93f68968e56d677b0d464 224 SMART SM00382 32 219 3.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04585 4e0d86b1deb93f68968e56d677b0d464 224 SUPERFAMILY SSF52540 3 221 9.04E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02500 c222845038c0ef4554d18c505b9e2d90 277 SUPERFAMILY SSF56784 2 276 2.07E-57 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02500 c222845038c0ef4554d18c505b9e2d90 277 Gene3D G3DSA:3.40.50.1000 1 277 3.8E-30 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02500 c222845038c0ef4554d18c505b9e2d90 277 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 270 5.9E-53 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02500 c222845038c0ef4554d18c505b9e2d90 277 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 242 4.3E-22 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS02500 c222845038c0ef4554d18c505b9e2d90 277 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 9 270 2.2E-50 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS08690 7defd01e6fbf171f541b00d591b36b08 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 20.428 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08690 7defd01e6fbf171f541b00d591b36b08 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 1.9E-28 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08690 7defd01e6fbf171f541b00d591b36b08 84 Gene3D G3DSA:3.30.1280.10 2 79 5.7E-29 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08690 7defd01e6fbf171f541b00d591b36b08 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 1.4E-29 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08690 7defd01e6fbf171f541b00d591b36b08 84 SUPERFAMILY SSF82697 1 80 3.84E-27 T 28-03-2018 CPF12_RS08690 7defd01e6fbf171f541b00d591b36b08 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 71 2.0E-18 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS07355 99136fa2a9004be3ad3ffc3c7c277958 130 SUPERFAMILY SSF55298 6 129 5.18E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS07355 99136fa2a9004be3ad3ffc3c7c277958 130 Pfam PF01042 Endoribonuclease L-PSP 12 127 8.0E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CPF12_RS07355 99136fa2a9004be3ad3ffc3c7c277958 130 Gene3D G3DSA:3.30.1330.40 1 130 8.1E-23 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 SUPERFAMILY SSF52518 1 175 1.18E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 Gene3D G3DSA:3.40.50.970 347 540 2.6E-34 T 28-03-2018 CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 175 1.3E-30 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 SUPERFAMILY SSF52518 354 544 4.29E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 PIRSF PIRSF036565 1 548 1.4E-204 T 28-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 515 4.3E-16 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 SUPERFAMILY SSF52467 163 344 7.48E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 307 9.5E-23 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 Gene3D G3DSA:3.40.50.970 1 192 1.2E-44 T 28-03-2018 CPF12_RS04620 a61aaa837d5b7629b5f86942d88389c8 548 Gene3D G3DSA:3.40.50.1220 193 346 2.4E-23 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CPF12_RS04170 d7a0c3ce09debd6760d3359a6bf04af3 131 Gene3D G3DSA:1.10.10.10 1 77 7.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04170 d7a0c3ce09debd6760d3359a6bf04af3 131 SMART SM00345 16 75 5.6E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS04170 d7a0c3ce09debd6760d3359a6bf04af3 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 3.1E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CPF12_RS04170 d7a0c3ce09debd6760d3359a6bf04af3 131 SUPERFAMILY SSF46785 5 79 3.99E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05480 a458ddc55f07084b88b00b0d0aec6c45 284 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 53 240 6.0E-65 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CPF12_RS05480 a458ddc55f07084b88b00b0d0aec6c45 284 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 244 30.17 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CPF12_RS05480 a458ddc55f07084b88b00b0d0aec6c45 284 Pfam PF02096 60Kd inner membrane protein 54 241 7.8E-60 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CPF12_RS05480 a458ddc55f07084b88b00b0d0aec6c45 284 PRINTS PR00701 60kDa inner membrane protein signature 23 43 5.2E-13 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CPF12_RS05480 a458ddc55f07084b88b00b0d0aec6c45 284 PRINTS PR00701 60kDa inner membrane protein signature 119 142 5.2E-13 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CPF12_RS05480 a458ddc55f07084b88b00b0d0aec6c45 284 PRINTS PR00701 60kDa inner membrane protein signature 207 230 5.2E-13 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CPF12_RS09070 0da6bf0da5bfb943633161c6af273ea3 147 SMART SM00731 4 144 3.9E-44 T 28-03-2018 IPR006640 SprT-like CPF12_RS09070 0da6bf0da5bfb943633161c6af273ea3 147 Pfam PF10263 SprT-like family 7 114 4.6E-14 T 28-03-2018 IPR006640 SprT-like CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 196 2.5E-40 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 SUPERFAMILY SSF54719 91 201 1.09E-45 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 SUPERFAMILY SSF46609 2 92 1.06E-38 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 1.0E-32 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 4.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 4.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 4.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 4.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 4.8E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 Gene3D G3DSA:1.10.287.990 21 91 3.0E-30 T 28-03-2018 CPF12_RS08790 dd311c111e1d044cc767ceb5bd0dc5aa 203 PIRSF PIRSF000349 1 203 2.2E-83 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CPF12_RS06070 aa9bd0817c6f279d3ecb244ec066c170 94 ProSitePatterns PS00050 Ribosomal protein L23 signature. 76 91 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS06070 aa9bd0817c6f279d3ecb244ec066c170 94 SUPERFAMILY SSF54189 1 90 2.52E-31 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06070 aa9bd0817c6f279d3ecb244ec066c170 94 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 94 21.784 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06070 aa9bd0817c6f279d3ecb244ec066c170 94 Gene3D G3DSA:3.30.70.330 1 94 6.6E-31 T 28-03-2018 CPF12_RS06070 aa9bd0817c6f279d3ecb244ec066c170 94 Pfam PF00276 Ribosomal protein L23 5 87 4.2E-29 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CPF12_RS05455 0ce67c9b4af516e79ee50dc7e62311aa 188 Pfam PF03641 Possible lysine decarboxylase 46 168 2.7E-33 T 28-03-2018 IPR031100 LOG family CPF12_RS05455 0ce67c9b4af516e79ee50dc7e62311aa 188 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 4 179 2.5E-47 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CPF12_RS05455 0ce67c9b4af516e79ee50dc7e62311aa 188 Gene3D G3DSA:3.40.50.450 1 178 2.9E-46 T 28-03-2018 CPF12_RS05455 0ce67c9b4af516e79ee50dc7e62311aa 188 SUPERFAMILY SSF102405 2 179 4.43E-53 T 28-03-2018 CPF12_RS04395 0855a8b0448d615fd31002629fc4fcc8 281 Gene3D G3DSA:3.40.50.1000 1 278 1.9E-31 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS04395 0855a8b0448d615fd31002629fc4fcc8 281 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 273 1.2E-49 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS04395 0855a8b0448d615fd31002629fc4fcc8 281 SUPERFAMILY SSF56784 4 277 1.8E-50 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS04395 0855a8b0448d615fd31002629fc4fcc8 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 272 2.5E-53 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS02095 1ccad6d0cc95ba461d3db2161f719b09 149 Gene3D G3DSA:1.20.1500.10 9 118 4.1E-28 T 28-03-2018 IPR023378 YheA/YmcA-like domain CPF12_RS02095 1ccad6d0cc95ba461d3db2161f719b09 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 10 116 7.7E-22 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CPF12_RS02095 1ccad6d0cc95ba461d3db2161f719b09 149 SUPERFAMILY SSF158622 4 126 5.76E-33 T 28-03-2018 IPR023378 YheA/YmcA-like domain CPF12_RS09695 0629720dc33868f6ec2ee43eee9e360a 356 Gene3D G3DSA:3.30.160.60 326 356 1.2E-7 T 28-03-2018 CPF12_RS09695 0629720dc33868f6ec2ee43eee9e360a 356 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 13 356 29.498 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CPF12_RS09695 0629720dc33868f6ec2ee43eee9e360a 356 Pfam PF02618 YceG-like family 50 352 2.3E-71 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CPF12_RS09695 0629720dc33868f6ec2ee43eee9e360a 356 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 13 355 7.0E-84 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CPF12_RS02595 ff79bfac8d4c03821cc1a19aa32fc34d 293 SUPERFAMILY SSF55120 71 292 1.06E-64 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS02595 ff79bfac8d4c03821cc1a19aa32fc34d 293 Gene3D G3DSA:3.30.2350.10 78 293 6.8E-60 T 28-03-2018 CPF12_RS02595 ff79bfac8d4c03821cc1a19aa32fc34d 293 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 292 1.4E-69 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS02595 ff79bfac8d4c03821cc1a19aa32fc34d 293 Pfam PF00849 RNA pseudouridylate synthase 88 237 4.0E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 318 50.674 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 SUPERFAMILY SSF53271 75 309 9.65E-66 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 318 8.5E-127 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 Gene3D G3DSA:3.40.50.2020 153 318 1.9E-48 T 28-03-2018 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 4.8E-51 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 SMART SM01400 10 126 1.0E-81 T 28-03-2018 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 Pfam PF14572 Phosphoribosyl synthetase-associated domain 209 317 1.1E-25 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CPF12_RS05755 bbd4c19f22b6b97a7ee726d200bd07e1 318 Gene3D G3DSA:3.40.50.2020 10 152 3.3E-64 T 28-03-2018 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 252 1.7E-82 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 Hamap MF_00258 Glutamate racemase [murI]. 3 255 39.843 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 SUPERFAMILY SSF53681 108 260 3.27E-37 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 SUPERFAMILY SSF53681 4 106 1.08E-36 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 213 3.4E-37 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 Gene3D G3DSA:3.40.50.1860 112 267 1.4E-39 T 28-03-2018 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 Gene3D G3DSA:3.40.50.1860 13 111 6.6E-24 T 28-03-2018 CPF12_RS01405 cf78b24e183e19fd741b30e55594f7cc 269 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS09220 c5e4093f06c56331dfc999ff24c03267 455 Gene3D G3DSA:2.40.50.140 22 107 2.3E-11 T 28-03-2018 CPF12_RS09220 c5e4093f06c56331dfc999ff24c03267 455 Pfam PF13742 OB-fold nucleic acid binding domain 11 106 1.1E-30 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CPF12_RS09220 c5e4093f06c56331dfc999ff24c03267 455 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 8 447 28.282 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09220 c5e4093f06c56331dfc999ff24c03267 455 Gene3D G3DSA:3.40.50.1970 111 257 9.9E-4 T 28-03-2018 CPF12_RS09220 c5e4093f06c56331dfc999ff24c03267 455 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 12 363 1.6E-132 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CPF12_RS09220 c5e4093f06c56331dfc999ff24c03267 455 Pfam PF02601 Exonuclease VII, large subunit 130 444 2.1E-96 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CPF12_RS08280 3166cd272266205385be2bff927deec2 310 Pfam PF00589 Phage integrase family 109 293 8.8E-23 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS08280 3166cd272266205385be2bff927deec2 310 SUPERFAMILY SSF56349 4 300 5.3E-49 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS08280 3166cd272266205385be2bff927deec2 310 Gene3D G3DSA:1.10.443.10 106 295 1.0E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS08280 3166cd272266205385be2bff927deec2 310 Gene3D G3DSA:1.10.150.130 2 104 2.1E-7 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CPF12_RS11755 2ae3d922a687c54a6ea4cfbcf473ca35 328 SUPERFAMILY SSF53067 95 190 2.07E-6 T 28-03-2018 CPF12_RS11755 2ae3d922a687c54a6ea4cfbcf473ca35 328 SUPERFAMILY SSF46785 9 71 6.13E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11755 2ae3d922a687c54a6ea4cfbcf473ca35 328 Gene3D G3DSA:1.10.10.10 2 81 4.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11755 2ae3d922a687c54a6ea4cfbcf473ca35 328 Gene3D G3DSA:3.30.420.40 91 195 6.3E-4 T 28-03-2018 CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 SMART SM00644 5 150 1.4E-14 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 SUPERFAMILY SSF55846 16 144 3.66E-23 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 Gene3D G3DSA:2.30.30.410 177 268 2.6E-12 T 28-03-2018 CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 19 141 2.1E-12 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 Pfam PF08460 Bacterial SH3 domain 194 255 1.7E-15 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 Gene3D G3DSA:3.40.80.10 1 176 9.2E-18 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CPF12_RS01255 c2df48c093fc2ead4a19d83be818aa1a 270 SMART SM00287 197 263 5.8E-6 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS07300 18f1e4970c966ff82cf3c49254686129 498 Gene3D G3DSA:1.50.10.20 110 321 2.2E-26 T 28-03-2018 CPF12_RS07300 18f1e4970c966ff82cf3c49254686129 498 SUPERFAMILY SSF48239 135 304 2.06E-19 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CPF12_RS07300 18f1e4970c966ff82cf3c49254686129 498 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 460 495 2.1E-4 T 28-03-2018 CPF12_RS07300 18f1e4970c966ff82cf3c49254686129 498 Pfam PF00746 LPXTG cell wall anchor motif 454 497 4.5E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS02315 9598d4a1a0669a620211127c39597c59 400 Gene3D G3DSA:3.60.70.12 4 272 1.8E-96 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS02315 9598d4a1a0669a620211127c39597c59 400 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 28 400 8.0E-113 T 28-03-2018 CPF12_RS02315 9598d4a1a0669a620211127c39597c59 400 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 7 400 3.0E-147 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS02315 9598d4a1a0669a620211127c39597c59 400 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 400 140.068 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS02315 9598d4a1a0669a620211127c39597c59 400 SUPERFAMILY SSF56266 11 396 1.07E-128 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS02315 9598d4a1a0669a620211127c39597c59 400 Pfam PF01960 ArgJ family 17 400 4.7E-142 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 134 196 4.4E-20 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 Gene3D G3DSA:1.10.150.320 137 198 3.8E-22 T 28-03-2018 CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 Pfam PF10531 SLBB domain 64 111 1.7E-11 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 Pfam PF12836 Helix-hairpin-helix motif 136 196 6.8E-20 T 28-03-2018 CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 Gene3D G3DSA:3.10.560.10 46 136 2.0E-12 T 28-03-2018 CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 SUPERFAMILY SSF47781 130 195 5.56E-23 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 SMART SM00278 176 195 0.22 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS09770 cb23fa8e842da38fbcedb6bc7b0e4f37 198 SMART SM00278 146 165 54.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CPF12_RS00085 4b0931a835873e20471d66b73f83b0fd 251 Pfam PF00977 Histidine biosynthesis protein 5 233 1.0E-85 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CPF12_RS00085 4b0931a835873e20471d66b73f83b0fd 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 250 1.3E-110 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CPF12_RS00085 4b0931a835873e20471d66b73f83b0fd 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 47.492 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CPF12_RS00085 4b0931a835873e20471d66b73f83b0fd 251 SUPERFAMILY SSF51366 1 250 4.95E-77 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS00085 4b0931a835873e20471d66b73f83b0fd 251 Gene3D G3DSA:3.20.20.70 4 246 3.3E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 SUPERFAMILY SSF53850 89 286 1.03E-20 T 28-03-2018 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 Gene3D G3DSA:3.40.190.10 176 262 5.8E-4 T 28-03-2018 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 SUPERFAMILY SSF46785 1 84 9.66E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 Gene3D G3DSA:3.40.190.10 87 175 5.4E-11 T 28-03-2018 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 Pfam PF03466 LysR substrate binding domain 88 287 1.6E-19 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 Gene3D G3DSA:1.10.10.10 1 83 9.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04930 33ce01f2d5c3fe0533438abf6c835816 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.1E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS05675 650b9a2eebd63ad2ecbcf2bd104c2fab 330 Gene3D G3DSA:1.20.272.10 220 328 1.0E-13 T 28-03-2018 CPF12_RS05675 650b9a2eebd63ad2ecbcf2bd104c2fab 330 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 14 199 6.6E-61 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS05675 650b9a2eebd63ad2ecbcf2bd104c2fab 330 Gene3D G3DSA:3.40.50.300 10 155 8.4E-28 T 28-03-2018 CPF12_RS05675 650b9a2eebd63ad2ecbcf2bd104c2fab 330 Pfam PF13177 DNA polymerase III, delta subunit 9 168 1.0E-54 T 28-03-2018 CPF12_RS05675 650b9a2eebd63ad2ecbcf2bd104c2fab 330 SUPERFAMILY SSF52540 9 201 1.77E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05675 650b9a2eebd63ad2ecbcf2bd104c2fab 330 Gene3D G3DSA:1.10.8.60 156 219 5.2E-5 T 28-03-2018 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 SUPERFAMILY SSF55174 1 54 1.14E-10 T 28-03-2018 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 Gene3D G3DSA:3.30.70.580 59 145 6.3E-20 T 28-03-2018 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 Gene3D G3DSA:3.30.70.1560 146 209 1.3E-18 T 28-03-2018 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 228 2.8E-43 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 Pfam PF00849 RNA pseudouridylate synthase 63 195 1.0E-22 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 SUPERFAMILY SSF55120 53 235 9.44E-42 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 Gene3D G3DSA:3.10.290.10 1 58 1.6E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 SMART SM00363 1 59 2.6E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS11245 9352e9a588d250f4cc2c5e0fa14dec47 238 Pfam PF01479 S4 domain 1 44 1.0E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS06375 5be62cbc01a0d07f0288bb257373c753 272 Pfam PF03099 Biotin/lipoate A/B protein ligase family 74 183 1.3E-12 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CPF12_RS06375 5be62cbc01a0d07f0288bb257373c753 272 Gene3D G3DSA:3.30.930.10 7 261 2.2E-34 T 28-03-2018 CPF12_RS06375 5be62cbc01a0d07f0288bb257373c753 272 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 2 271 40.222 T 28-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 CPF12_RS06375 5be62cbc01a0d07f0288bb257373c753 272 SUPERFAMILY SSF55681 10 254 7.21E-61 T 28-03-2018 CPF12_RS04700 9eabf80be77fda3c57f2c53731e79998 272 Gene3D G3DSA:3.40.50.300 54 176 1.0E-4 T 28-03-2018 CPF12_RS04700 9eabf80be77fda3c57f2c53731e79998 272 Pfam PF13175 AAA ATPase domain 178 227 1.0E-9 T 28-03-2018 CPF12_RS04700 9eabf80be77fda3c57f2c53731e79998 272 SUPERFAMILY SSF52540 35 238 9.23E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04700 9eabf80be77fda3c57f2c53731e79998 272 SMART SM00382 35 242 5.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS04700 9eabf80be77fda3c57f2c53731e79998 272 Gene3D G3DSA:3.40.50.300 177 238 5.7E-10 T 28-03-2018 CPF12_RS04700 9eabf80be77fda3c57f2c53731e79998 272 Gene3D G3DSA:3.40.50.300 11 53 9.6E-4 T 28-03-2018 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 9 345 43.108 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 344 2.2E-112 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 Gene3D G3DSA:3.20.20.210 7 347 5.5E-88 T 28-03-2018 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 SUPERFAMILY SSF51726 8 345 1.44E-90 T 28-03-2018 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 25 34 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CPF12_RS12475 4e23f80e0fea1e47815f7eb59983ae5d 349 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 12 342 5.8E-118 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 288 5.6E-96 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 Pfam PF00294 pfkB family carbohydrate kinase 1 283 4.0E-64 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 Hamap MF_01987 Ribokinase [rbsK]. 2 290 24.177 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 SUPERFAMILY SSF53613 1 291 4.21E-74 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 Gene3D G3DSA:3.40.1190.20 1 293 2.2E-69 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 235 248 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 PRINTS PR00990 Ribokinase signature 172 187 1.5E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 PRINTS PR00990 Ribokinase signature 104 117 1.5E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 PRINTS PR00990 Ribokinase signature 6 27 1.5E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 PRINTS PR00990 Ribokinase signature 207 218 1.5E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CPF12_RS01710 dad62663fe0785404b6f0278d6cb4d79 293 PRINTS PR00990 Ribokinase signature 33 52 1.5E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CPF12_RS06970 bc2a5d1ab6283032c081c25ebb1e595c 82 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 72 6.0E-23 T 28-03-2018 CPF12_RS06970 bc2a5d1ab6283032c081c25ebb1e595c 82 Pfam PF07293 Protein of unknown function (DUF1450) 1 73 1.7E-30 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 4.1E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 SUPERFAMILY SSF50129 1 150 6.85E-33 T 28-03-2018 IPR011032 GroES-like CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 SUPERFAMILY SSF51735 112 270 2.0E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 SMART SM00829 10 320 1.1E-23 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 Pfam PF00107 Zinc-binding dehydrogenase 152 260 6.0E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 Gene3D G3DSA:3.90.180.10 1 153 2.9E-42 T 28-03-2018 CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 Gene3D G3DSA:3.40.50.720 154 264 7.9E-20 T 28-03-2018 CPF12_RS03095 bfdbc3d4f2fda27c64dc510ae5b87e7a 322 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Gene3D G3DSA:3.30.1330.10 421 569 1.7E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 SUPERFAMILY SSF55326 402 572 6.54E-56 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 362 2.0E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 579 708 9.6E-15 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Gene3D G3DSA:3.90.650.10 202 380 3.6E-27 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Gene3D G3DSA:3.90.650.10 571 739 1.6E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 SUPERFAMILY SSF55326 18 202 2.99E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 SUPERFAMILY SSF56042 574 738 7.33E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 7.7E-291 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 SUPERFAMILY SSF56042 205 432 1.36E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 739 314.45 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 447 564 1.1E-23 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 93 194 3.6E-24 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 PIRSF PIRSF001587 8 739 0.0 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08700 faf995e3cabf51c86a23739913e81739 739 Gene3D G3DSA:3.30.1330.10 24 199 6.0E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS07370 ed6ced03ad5b8bb4df07ebbb96b1a75c 341 Pfam PF06030 Bacterial protein of unknown function (DUF916) 34 154 1.1E-29 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CPF12_RS07370 ed6ced03ad5b8bb4df07ebbb96b1a75c 341 Gene3D G3DSA:2.60.40.1710 41 168 3.5E-8 T 28-03-2018 CPF12_RS07370 ed6ced03ad5b8bb4df07ebbb96b1a75c 341 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 168 303 5.8E-28 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CPF12_RS04575 324cc8781e6e1075b3dd4bf6c5728bc7 190 Gene3D G3DSA:3.40.630.30 4 132 2.5E-14 T 28-03-2018 CPF12_RS04575 324cc8781e6e1075b3dd4bf6c5728bc7 190 SUPERFAMILY SSF55729 6 139 2.95E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS04575 324cc8781e6e1075b3dd4bf6c5728bc7 190 Pfam PF00583 Acetyltransferase (GNAT) family 38 132 1.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS03420 a1bed1ec273203d90277e6d07936e777 302 Pfam PF00762 Ferrochelatase 1 296 1.6E-76 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CPF12_RS03420 a1bed1ec273203d90277e6d07936e777 302 Hamap MF_00323 Ferrochelatase [hemH]. 1 298 27.662 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CPF12_RS03420 a1bed1ec273203d90277e6d07936e777 302 TIGRFAM TIGR00109 hemH: ferrochelatase 1 298 2.8E-76 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CPF12_RS03420 a1bed1ec273203d90277e6d07936e777 302 Gene3D G3DSA:3.40.50.1400 1 147 1.4E-19 T 28-03-2018 CPF12_RS03420 a1bed1ec273203d90277e6d07936e777 302 Gene3D G3DSA:3.40.50.1400 148 279 4.3E-37 T 28-03-2018 CPF12_RS03420 a1bed1ec273203d90277e6d07936e777 302 SUPERFAMILY SSF53800 1 297 1.08E-77 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 Gene3D G3DSA:3.10.150.10 130 256 2.8E-31 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 6.2E-35 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 380 2.4E-106 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 367 2.0E-28 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 Gene3D G3DSA:3.10.150.10 257 381 4.0E-24 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 SUPERFAMILY SSF55979 254 380 3.56E-27 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 PIRSF PIRSF000804 1 381 3.4E-109 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 SMART SM00480 17 376 5.3E-129 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 Gene3D G3DSA:3.10.150.10 1 129 3.6E-29 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 SUPERFAMILY SSF55979 1 127 3.14E-26 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 SUPERFAMILY SSF55979 135 251 1.47E-26 T 28-03-2018 CPF12_RS05500 4e3fd8a1a9db06af2248b3b6fb36a2e9 381 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 1.5E-34 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CPF12_RS12065 cd8bf827178355e183a14cb37a8a0cac 459 PIRSF PIRSF006060 1 459 3.5E-71 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CPF12_RS12065 cd8bf827178355e183a14cb37a8a0cac 459 Pfam PF00324 Amino acid permease 16 454 4.6E-116 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CPF12_RS09370 d6e81fd3bea2d7985ed487e3e29b1f37 209 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 14 198 2.9E-41 T 28-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CPF12_RS04970 a82f5dcc5cbd1fd1680b6ecb9999aa6f 787 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 417 756 5.0E-59 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CPF12_RS04970 a82f5dcc5cbd1fd1680b6ecb9999aa6f 787 Gene3D G3DSA:3.40.50.2000 594 724 0.0016 T 28-03-2018 CPF12_RS04970 a82f5dcc5cbd1fd1680b6ecb9999aa6f 787 SUPERFAMILY SSF53756 8 343 3.77E-19 T 28-03-2018 CPF12_RS04970 a82f5dcc5cbd1fd1680b6ecb9999aa6f 787 Gene3D G3DSA:3.40.50.2000 129 346 1.0E-8 T 28-03-2018 CPF12_RS04970 a82f5dcc5cbd1fd1680b6ecb9999aa6f 787 SUPERFAMILY SSF53756 445 715 1.22E-7 T 28-03-2018 CPF12_RS04970 a82f5dcc5cbd1fd1680b6ecb9999aa6f 787 Pfam PF00534 Glycosyl transferases group 1 164 296 3.3E-6 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CPF12_RS04605 77cc7a796ebe04fcb68ae441d5f110fe 200 Gene3D G3DSA:2.60.120.200 2 191 4.2E-33 T 28-03-2018 CPF12_RS04605 77cc7a796ebe04fcb68ae441d5f110fe 200 Pfam PF07081 Protein of unknown function (DUF1349) 12 189 5.1E-58 T 28-03-2018 IPR009784 Protein of unknown function DUF1349 CPF12_RS04605 77cc7a796ebe04fcb68ae441d5f110fe 200 PIRSF PIRSF022704 2 198 1.5E-57 T 28-03-2018 IPR015987 Uncharacterised conserved protein UCP022704 CPF12_RS04605 77cc7a796ebe04fcb68ae441d5f110fe 200 SUPERFAMILY SSF49899 8 189 2.18E-27 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CPF12_RS07785 4fcd10f6cbf4f2ee7ab8eebc51d69021 117 Gene3D G3DSA:3.40.30.10 1 116 1.4E-35 T 28-03-2018 CPF12_RS07785 4fcd10f6cbf4f2ee7ab8eebc51d69021 117 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 116 1.0E-35 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CPF12_RS07785 4fcd10f6cbf4f2ee7ab8eebc51d69021 117 Pfam PF03960 ArsC family 9 113 6.6E-15 T 28-03-2018 IPR006660 Arsenate reductase-like CPF12_RS07785 4fcd10f6cbf4f2ee7ab8eebc51d69021 117 SUPERFAMILY SSF52833 1 116 9.07E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS08830 3d2029c7402eafef91e9169dcef8d0f3 248 Gene3D G3DSA:2.40.50.40 139 208 1.8E-7 T 28-03-2018 CPF12_RS08830 3d2029c7402eafef91e9169dcef8d0f3 248 Pfam PF00072 Response regulator receiver domain 3 113 4.1E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS08830 3d2029c7402eafef91e9169dcef8d0f3 248 SMART SM00850 146 247 0.0011 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS08830 3d2029c7402eafef91e9169dcef8d0f3 248 Gene3D G3DSA:3.40.50.2300 1 138 9.2E-9 T 28-03-2018 CPF12_RS08830 3d2029c7402eafef91e9169dcef8d0f3 248 SUPERFAMILY SSF52172 1 129 2.7E-9 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS08830 3d2029c7402eafef91e9169dcef8d0f3 248 Pfam PF04397 LytTr DNA-binding domain 151 244 6.3E-9 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 SMART SM00347 27 125 6.8E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 Pfam PF01047 MarR family 34 85 5.3E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 SUPERFAMILY SSF46785 8 138 9.59E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 Gene3D G3DSA:1.10.10.10 6 136 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS03085 debc7ff34000a86988acb9a1c3dbfa99 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.3E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS03720 7b27eed0a95bbedd789a310d25f15655 340 SUPERFAMILY SSF161098 133 324 8.9E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS03720 7b27eed0a95bbedd789a310d25f15655 340 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 35 85 3.3E-15 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CPF12_RS03720 7b27eed0a95bbedd789a310d25f15655 340 Gene3D G3DSA:1.10.3720.10 37 328 1.8E-45 T 28-03-2018 CPF12_RS03720 7b27eed0a95bbedd789a310d25f15655 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 156 339 2.3E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02965 4b072b487c587f05d0ba650ea84fb9a5 239 Gene3D G3DSA:2.60.120.10 26 152 1.6E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS02965 4b072b487c587f05d0ba650ea84fb9a5 239 SUPERFAMILY SSF46785 187 235 1.58E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02965 4b072b487c587f05d0ba650ea84fb9a5 239 Pfam PF13545 Crp-like helix-turn-helix domain 166 232 5.7E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CPF12_RS02965 4b072b487c587f05d0ba650ea84fb9a5 239 Gene3D G3DSA:1.10.10.10 153 238 2.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02965 4b072b487c587f05d0ba650ea84fb9a5 239 SUPERFAMILY SSF51206 37 151 1.11E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CPF12_RS02965 4b072b487c587f05d0ba650ea84fb9a5 239 Pfam PF00027 Cyclic nucleotide-binding domain 46 128 1.7E-11 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 Gene3D G3DSA:3.40.50.300 125 265 2.8E-25 T 28-03-2018 CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 Gene3D G3DSA:3.40.50.300 1 124 4.3E-27 T 28-03-2018 CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 SUPERFAMILY SSF52540 300 724 7.59E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 Pfam PF12705 PD-(D/E)XK nuclease superfamily 785 1126 1.5E-53 T 28-03-2018 CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 Gene3D G3DSA:3.90.320.10 726 993 5.9E-11 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 Gene3D G3DSA:3.40.50.300 266 691 2.2E-29 T 28-03-2018 CPF12_RS02815 7fb8fa16e6d8d6ef646e0eadccb10d84 1160 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 2 1157 0.0 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 Gene3D G3DSA:3.40.50.1360 72 258 9.1E-35 T 28-03-2018 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 SMART SM01134 71 233 9.4E-58 T 28-03-2018 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 SMART SM00420 5 57 4.8E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 Pfam PF00455 DeoR C terminal sensor domain 73 232 6.0E-48 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 1.9E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 1.9E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 Pfam PF08220 DeoR-like helix-turn-helix domain 5 58 8.4E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 SUPERFAMILY SSF46785 4 58 5.96E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 Gene3D G3DSA:1.10.10.10 1 71 1.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10960 b02c56402352341d6b942ee6e3063cbb 260 SUPERFAMILY SSF100950 74 233 3.71E-31 T 28-03-2018 CPF12_RS12270 9ee3441dff9176671b4eb620c83449b3 227 TIGRFAM TIGR01866 cas_Csn2: CRISPR type II-A/NMEMI-associated protein Csn2 2 224 1.8E-39 T 28-03-2018 IPR010146 CRISPR-associated protein, Csn2-type CPF12_RS12270 9ee3441dff9176671b4eb620c83449b3 227 Pfam PF09711 CRISPR-associated protein (Cas_Csn2) 50 222 1.2E-21 T 28-03-2018 IPR010146 CRISPR-associated protein, Csn2-type CPF12_RS04140 0d203713a8bc55297c92ce232cdf489f 253 Gene3D G3DSA:1.20.1080.10 2 253 1.6E-77 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CPF12_RS04140 0d203713a8bc55297c92ce232cdf489f 253 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 74 83 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site CPF12_RS04140 0d203713a8bc55297c92ce232cdf489f 253 Pfam PF01226 Formate/nitrite transporter 7 247 2.7E-71 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CPF12_RS10525 ccfd3f9497cb6603e45a33955098907e 288 Gene3D G3DSA:3.30.420.40 115 285 8.2E-42 T 28-03-2018 CPF12_RS10525 ccfd3f9497cb6603e45a33955098907e 288 SUPERFAMILY SSF53067 1 286 3.66E-51 T 28-03-2018 CPF12_RS10525 ccfd3f9497cb6603e45a33955098907e 288 Gene3D G3DSA:3.30.420.40 1 114 1.4E-19 T 28-03-2018 CPF12_RS10525 ccfd3f9497cb6603e45a33955098907e 288 Pfam PF00480 ROK family 4 283 3.3E-41 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS11575 3bacf7deef38d866d660ed2350813060 408 Gene3D G3DSA:1.20.1250.20 8 203 2.4E-20 T 28-03-2018 CPF12_RS11575 3bacf7deef38d866d660ed2350813060 408 Gene3D G3DSA:1.20.1250.20 207 398 9.3E-5 T 28-03-2018 CPF12_RS11575 3bacf7deef38d866d660ed2350813060 408 SUPERFAMILY SSF103473 14 397 1.57E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS11575 3bacf7deef38d866d660ed2350813060 408 Pfam PF07690 Major Facilitator Superfamily 16 356 2.9E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 PIRSF PIRSF000408 1 185 1.5E-68 T 28-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 Gene3D G3DSA:1.10.10.60 75 131 2.7E-10 T 28-03-2018 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 Gene3D G3DSA:1.10.10.60 132 184 6.3E-11 T 28-03-2018 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 Pfam PF02805 Metal binding domain of Ada 8 69 6.2E-25 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 SMART SM00342 94 177 3.4E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 SUPERFAMILY SSF46689 78 125 3.14E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 SUPERFAMILY SSF57884 5 81 3.14E-25 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 Pfam PF12833 Helix-turn-helix domain 104 178 5.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 SUPERFAMILY SSF46689 130 180 4.93E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS05295 09b12058ef35dc911df74ae9b7363305 186 Gene3D G3DSA:3.40.10.10 1 71 4.8E-19 T 28-03-2018 IPR035451 Ada-like domain CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 Gene3D G3DSA:3.40.50.620 2 160 1.6E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 SUPERFAMILY SSF52374 4 158 2.23E-39 T 28-03-2018 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 62 9.4E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 Pfam PF01467 Cytidylyltransferase-like 7 135 6.5E-14 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 159 3.4E-55 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 4.9E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 87 103 4.9E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 114 136 4.9E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 4.9E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 4.9E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS02080 ff17c0215e8285d0bae8730463e5bad9 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 160 31.574 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CPF12_RS05100 d3fc1fd6a0f9a2bdfc7a190d571df9ff 49 SUPERFAMILY SSF57829 1 49 1.53E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CPF12_RS05100 d3fc1fd6a0f9a2bdfc7a190d571df9ff 49 Pfam PF00471 Ribosomal protein L33 4 49 2.6E-21 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05100 d3fc1fd6a0f9a2bdfc7a190d571df9ff 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 17.349 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05100 d3fc1fd6a0f9a2bdfc7a190d571df9ff 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS05100 d3fc1fd6a0f9a2bdfc7a190d571df9ff 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 4 49 2.2E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 102 2.1E-32 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 Gene3D G3DSA:3.10.28.10 2 104 2.1E-10 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 2.7E-34 T 28-03-2018 CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 34.489 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 Gene3D G3DSA:3.10.28.10 116 218 1.2E-17 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 SUPERFAMILY SSF55608 116 221 8.93E-20 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.4E-36 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CPF12_RS06815 e093ae26ce2d176ffbb3b368f4ff4db7 319 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 5.7E-119 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 609 724 2.09E-23 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 887 1026 4.32E-33 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 1073 1207 1.83E-35 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 38 175 5.49E-23 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Gene3D G3DSA:2.160.20.50 1013 1074 0.0031 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 734 871 4.05E-30 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 189 304 2.49E-23 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 326 442 4.2E-23 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 1083 1198 2.8E-28 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 186 302 3.0E-23 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 466 582 4.2E-23 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 37 170 1.9E-24 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 606 722 4.4E-23 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 897 1015 6.4E-26 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 746 865 1.2E-25 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 Pfam PF05031 Iron Transport-associated domain 1254 1369 2.7E-28 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 897 1022 3.6E-31 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 467 588 4.6E-26 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 747 872 3.4E-32 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 1252 1376 2.8E-44 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 1081 1205 8.2E-41 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 35 177 2.4E-30 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 327 448 4.6E-26 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 187 308 8.8E-27 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SMART SM00725 607 728 1.1E-25 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 329 444 2.09E-23 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 1243 1375 1.96E-34 T 28-03-2018 CPF12_RS09880 763be589c77389f9b2539af7046c3d87 1474 SUPERFAMILY SSF158911 469 584 2.09E-23 T 28-03-2018 CPF12_RS11280 60d2f28e604583c4fbf9097ac82fffa8 73 Pfam PF11213 Protein of unknown function (DUF3006) 5 70 1.6E-18 T 28-03-2018 IPR021377 Protein of unknown function DUF3006 CPF12_RS05800 7e5dea1f4d60e50e2425f99015022f5b 145 Gene3D G3DSA:2.40.50.140 7 137 4.9E-27 T 28-03-2018 CPF12_RS05800 7e5dea1f4d60e50e2425f99015022f5b 145 SMART SM00316 4 74 2.5E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS05800 7e5dea1f4d60e50e2425f99015022f5b 145 Pfam PF00575 S1 RNA binding domain 4 74 5.1E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS05800 7e5dea1f4d60e50e2425f99015022f5b 145 SUPERFAMILY SSF50249 4 84 6.6E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 SUPERFAMILY SSF46785 1 87 3.29E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 Gene3D G3DSA:1.10.10.10 1 89 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 Gene3D G3DSA:3.40.190.10 175 264 4.3E-18 T 28-03-2018 CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 Gene3D G3DSA:3.40.190.10 90 174 3.1E-16 T 28-03-2018 CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 Pfam PF03466 LysR substrate binding domain 88 288 2.0E-42 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS04540 e598e61ed02f4c825f2ec3bd74fae124 292 SUPERFAMILY SSF53850 89 291 5.43E-42 T 28-03-2018 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 Pfam PF02110 Hydroxyethylthiazole kinase family 5 250 3.2E-86 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 Gene3D G3DSA:3.40.1190.20 1 266 2.3E-54 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 5 250 1.3E-87 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PIRSF PIRSF000513 1 263 4.4E-91 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 26 47 4.0E-39 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 13 20 4.0E-39 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 57 65 4.0E-39 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 114 128 4.0E-39 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 158 175 4.0E-39 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 83 100 4.0E-39 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 SUPERFAMILY SSF53613 3 261 1.94E-59 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS04535 9ef5742394e1e60630af38b48b5e5e89 268 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 7 255 32.215 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS04785 9de0c7e0902f65a168cf2074f81fbf84 368 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 365 1.9E-151 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CPF12_RS04785 9de0c7e0902f65a168cf2074f81fbf84 368 Gene3D G3DSA:3.40.50.2000 4 204 1.6E-76 T 28-03-2018 CPF12_RS04785 9de0c7e0902f65a168cf2074f81fbf84 368 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 364 1.3E-114 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CPF12_RS04785 9de0c7e0902f65a168cf2074f81fbf84 368 Gene3D G3DSA:3.40.50.2000 205 345 1.1E-37 T 28-03-2018 CPF12_RS04785 9de0c7e0902f65a168cf2074f81fbf84 368 SUPERFAMILY SSF53756 3 366 8.37E-130 T 28-03-2018 CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 6.3E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 SUPERFAMILY SSF51735 2 247 1.95E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 Gene3D G3DSA:3.40.50.720 1 248 3.6E-68 T 28-03-2018 CPF12_RS09980 319cab8e9a582ab91499f8e0dde4f40e 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 244 3.4E-68 T 28-03-2018 CPF12_RS07420 d30712f62eb81d3298c02f532d904050 330 Pfam PF06030 Bacterial protein of unknown function (DUF916) 30 145 8.8E-29 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CPF12_RS07420 d30712f62eb81d3298c02f532d904050 330 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 152 287 7.6E-30 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CPF12_RS07420 d30712f62eb81d3298c02f532d904050 330 Gene3D G3DSA:2.60.40.10 45 169 2.2E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS07420 d30712f62eb81d3298c02f532d904050 330 Gene3D G3DSA:2.60.40.10 179 278 0.11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS06015 3c5bdca00fa2d27a2059028e62d2b272 200 Pfam PF05175 Methyltransferase small domain 28 196 5.2E-49 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CPF12_RS06015 3c5bdca00fa2d27a2059028e62d2b272 200 Gene3D G3DSA:3.40.50.150 12 200 1.5E-27 T 28-03-2018 CPF12_RS06015 3c5bdca00fa2d27a2059028e62d2b272 200 SUPERFAMILY SSF53335 7 195 2.03E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 Gene3D G3DSA:3.40.50.2300 2 134 1.9E-39 T 28-03-2018 CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 SMART SM00448 2 113 6.1E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 SUPERFAMILY SSF52172 3 130 6.55E-42 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 2.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 SMART SM00862 150 225 8.7E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 Gene3D G3DSA:1.10.10.10 135 227 2.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 SUPERFAMILY SSF46894 127 225 2.3E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS00985 55ffffcc3e7a9db56f22c39bf9795cac 227 Pfam PF00072 Response regulator receiver domain 4 113 8.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 Gene3D G3DSA:1.10.8.60 168 243 3.5E-18 T 28-03-2018 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 241 360 4.9E-10 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 125 143 5.4E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 5.4E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 SUPERFAMILY SSF52540 31 225 5.77E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 Gene3D G3DSA:1.20.272.10 244 362 9.7E-15 T 28-03-2018 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 9.0E-140 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 Pfam PF13177 DNA polymerase III, delta subunit 20 179 3.8E-46 T 28-03-2018 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 SMART SM00382 37 180 3.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 Gene3D G3DSA:3.40.50.300 15 167 8.2E-41 T 28-03-2018 CPF12_RS05640 28be3b1b18b6c4ff1816d40d8d213e6d 594 SUPERFAMILY SSF48019 247 359 7.23E-22 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CPF12_RS03525 eda604d9003e619063a3368acb8a8010 373 Pfam PF04203 Sortase family 100 225 6.9E-22 T 28-03-2018 IPR005754 Sortase family CPF12_RS03525 eda604d9003e619063a3368acb8a8010 373 TIGRFAM TIGR01076 sortase_fam: sortase 98 232 3.8E-45 T 28-03-2018 IPR005754 Sortase family CPF12_RS03525 eda604d9003e619063a3368acb8a8010 373 Gene3D G3DSA:2.40.260.10 35 243 4.1E-42 T 28-03-2018 IPR023365 Sortase domain CPF12_RS03525 eda604d9003e619063a3368acb8a8010 373 SUPERFAMILY SSF63817 89 229 1.57E-40 T 28-03-2018 IPR023365 Sortase domain CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 199 2.8E-66 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 SUPERFAMILY SSF142695 207 375 5.36E-58 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 205 400 37.806 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 Gene3D G3DSA:3.90.870.10 2 211 1.2E-80 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 PIRSF PIRSF001259 2 401 1.0E-150 T 28-03-2018 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 1.5E-74 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 203 36.185 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 Pfam PF00925 GTP cyclohydrolase II 211 373 4.2E-63 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 SUPERFAMILY SSF55821 5 200 7.78E-74 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CPF12_RS04810 81b59ae04215c0ba9c3bcd9413dcc992 401 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 211 398 4.9E-70 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 Pfam PF00753 Metallo-beta-lactamase superfamily 498 679 3.1E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 Pfam PF03772 Competence protein 203 463 1.6E-55 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 Pfam PF13567 Domain of unknown function (DUF4131) 27 165 9.6E-15 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 85 739 4.1E-106 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 SUPERFAMILY SSF56281 489 746 1.18E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 224 393 4.0E-33 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 SMART SM00849 500 710 7.1E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS09780 3771da374740de33c2ea868bfe2e4c9e 747 Gene3D G3DSA:3.60.15.10 480 732 2.0E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS01855 dc580c4d9989b71cf98dc2f70a72b0f1 104 Pfam PF06305 Lipopolysaccharide assembly protein A domain 25 83 3.6E-15 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CPF12_RS01440 abae8b32dfeef08d367de0ffc45595a2 352 PIRSF PIRSF037431 3 351 2.6E-115 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CPF12_RS01440 abae8b32dfeef08d367de0ffc45595a2 352 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 344 1.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS01440 abae8b32dfeef08d367de0ffc45595a2 352 SUPERFAMILY SSF55874 223 344 4.71E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS01440 abae8b32dfeef08d367de0ffc45595a2 352 SMART SM00387 252 347 2.5E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS01440 abae8b32dfeef08d367de0ffc45595a2 352 Gene3D G3DSA:3.30.565.10 215 352 3.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS01440 abae8b32dfeef08d367de0ffc45595a2 352 Pfam PF07730 Histidine kinase 147 215 5.1E-20 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 SUPERFAMILY SSF50104 1 63 4.81E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.1E-23 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 SUPERFAMILY SSF50249 128 185 5.82E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 SUPERFAMILY SSF50249 65 129 1.71E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Gene3D G3DSA:2.40.50.140 64 127 6.3E-20 T 28-03-2018 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Gene3D G3DSA:2.30.30.30 2 60 1.3E-22 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 SMART SM01185 67 121 1.0E-18 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 46.624 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 9.5E-17 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 SMART SM00841 129 184 1.0E-30 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Gene3D G3DSA:2.40.50.140 129 184 1.7E-24 T 28-03-2018 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 PIRSF PIRSF005901 1 186 4.1E-66 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 1.5E-69 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CPF12_RS04715 484f72ea532ad491cc1bfc1d8cb67b95 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 2.1E-24 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CPF12_RS04660 fb0033c6ee729840160ac5c043d9cd34 170 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 50 3.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS04660 fb0033c6ee729840160ac5c043d9cd34 170 Gene3D G3DSA:1.10.10.60 4 39 5.2E-8 T 28-03-2018 CPF12_RS04660 fb0033c6ee729840160ac5c043d9cd34 170 SUPERFAMILY SSF46689 5 61 8.72E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS04660 fb0033c6ee729840160ac5c043d9cd34 170 Gene3D G3DSA:1.10.10.60 40 155 2.3E-4 T 28-03-2018 CPF12_RS01110 08a291dc2f37a6e7691f0710da5016ef 224 SUPERFAMILY SSF47781 14 88 1.89E-6 T 28-03-2018 IPR010994 RuvA domain 2-like CPF12_RS01110 08a291dc2f37a6e7691f0710da5016ef 224 Pfam PF04002 RadC-like JAB domain 102 221 1.8E-39 T 28-03-2018 IPR025657 RadC-like JAB domain CPF12_RS01110 08a291dc2f37a6e7691f0710da5016ef 224 Gene3D G3DSA:1.10.150.20 31 89 1.4E-6 T 28-03-2018 CPF12_RS01110 08a291dc2f37a6e7691f0710da5016ef 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 222 3.7E-64 T 28-03-2018 IPR001405 RadC protein CPF12_RS01110 08a291dc2f37a6e7691f0710da5016ef 224 Gene3D G3DSA:3.40.140.10 98 223 8.0E-42 T 28-03-2018 CPF12_RS01110 08a291dc2f37a6e7691f0710da5016ef 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 172 177 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CPF12_RS11260 6cfc662f551a1d4a8d9bfcafac3e568d 181 SUPERFAMILY SSF55729 4 172 2.34E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS11260 6cfc662f551a1d4a8d9bfcafac3e568d 181 Gene3D G3DSA:3.40.630.30 1 178 7.0E-24 T 28-03-2018 CPF12_RS11260 6cfc662f551a1d4a8d9bfcafac3e568d 181 Pfam PF13302 Acetyltransferase (GNAT) domain 7 148 1.6E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS07760 2a3344f6564bfc1fc19afa66ba0bfb5a 54 Pfam PF05532 CsbD-like 2 50 2.0E-16 T 28-03-2018 IPR008462 CsbD-like domain CPF12_RS07760 2a3344f6564bfc1fc19afa66ba0bfb5a 54 Gene3D G3DSA:1.10.1470.10 1 54 5.6E-15 T 28-03-2018 IPR008462 CsbD-like domain CPF12_RS07760 2a3344f6564bfc1fc19afa66ba0bfb5a 54 SUPERFAMILY SSF69047 2 53 1.83E-11 T 28-03-2018 IPR008462 CsbD-like domain CPF12_RS09320 9896ac14ae65f17a09320d84ec709aea 250 Gene3D G3DSA:2.40.50.140 187 250 3.9E-7 T 28-03-2018 CPF12_RS09320 9896ac14ae65f17a09320d84ec709aea 250 SUPERFAMILY SSF141322 188 248 7.32E-6 T 28-03-2018 CPF12_RS09320 9896ac14ae65f17a09320d84ec709aea 250 Pfam PF01957 NfeD-like C-terminal, partner-binding 101 248 1.2E-13 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain CPF12_RS12280 27321268a6c2843ba75d2a1ed5b5d51f 290 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 3 271 1.0E-91 T 28-03-2018 IPR019855 CRISPR-associated protein Cas1, NMENI subtype GO:0004520|GO:0043571|GO:0046872 CPF12_RS12280 27321268a6c2843ba75d2a1ed5b5d51f 290 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 284 17.177 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CPF12_RS12280 27321268a6c2843ba75d2a1ed5b5d51f 290 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 235 2.8E-26 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CPF12_RS12280 27321268a6c2843ba75d2a1ed5b5d51f 290 Pfam PF01867 CRISPR associated protein Cas1 7 233 1.1E-24 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CPF12_RS00415 44f8a230d9032c4054bf9339717068f9 200 SUPERFAMILY SSF55658 5 49 8.89E-14 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CPF12_RS00415 44f8a230d9032c4054bf9339717068f9 200 Gene3D G3DSA:3.40.970.10 2 54 1.1E-22 T 28-03-2018 IPR011320 Ribonuclease H1, N-terminal CPF12_RS00415 44f8a230d9032c4054bf9339717068f9 200 Pfam PF01693 Caulimovirus viroplasmin 5 48 1.1E-17 T 28-03-2018 IPR011320 Ribonuclease H1, N-terminal CPF12_RS00415 44f8a230d9032c4054bf9339717068f9 200 Pfam PF00075 RNase H 67 198 3.3E-13 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CPF12_RS00415 44f8a230d9032c4054bf9339717068f9 200 Gene3D G3DSA:3.30.420.10 66 199 7.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS00415 44f8a230d9032c4054bf9339717068f9 200 SUPERFAMILY SSF53098 68 198 2.02E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 Hamap MF_00740 Phosphopentomutase [deoB]. 5 390 54.399 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 SUPERFAMILY SSF143856 102 219 5.1E-49 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 Gene3D G3DSA:3.30.70.1250 101 205 7.1E-54 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 Pfam PF01676 Metalloenzyme superfamily 6 381 7.3E-43 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 PIRSF PIRSF001491 4 394 7.3E-160 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 Gene3D G3DSA:3.40.720.10 206 394 3.7E-15 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 SUPERFAMILY SSF53649 220 392 1.57E-76 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 SUPERFAMILY SSF53649 4 102 1.57E-76 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS03165 0e7fc65f73d2a52a3ae7a15fed43e0c1 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 7 388 1.4E-188 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 SUPERFAMILY SSF55604 6 81 1.7E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 Gene3D G3DSA:3.30.1360.60 4 80 6.1E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 491 615 6.2E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 636 1.4E-225 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 Gene3D G3DSA:2.70.70.10 480 637 9.2E-56 T 28-03-2018 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 Pfam PF00367 phosphotransferase system, EIIB 10 41 4.6E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 Pfam PF02378 Phosphotransferase system, EIIC 106 404 1.2E-29 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 SUPERFAMILY SSF51261 484 635 1.74E-52 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 492 612 7.4E-42 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04355 cc9d7e3026259dfff89d71f4e1c2344a 637 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 554 566 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 300 2.4E-30 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 SUPERFAMILY SSF53822 57 295 3.62E-38 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 Gene3D G3DSA:3.40.50.2300 53 171 2.5E-25 T 28-03-2018 CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 SMART SM00354 1 70 9.5E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 Gene3D G3DSA:1.10.260.40 1 52 3.3E-21 T 28-03-2018 CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 47 2.8E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 Gene3D G3DSA:3.40.50.2300 172 296 1.5E-20 T 28-03-2018 CPF12_RS11275 e0e9fe8b4c68283fd4572e1f26fa86d2 310 SUPERFAMILY SSF47413 2 58 3.1E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 Pfam PF00294 pfkB family carbohydrate kinase 6 282 7.1E-46 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 Gene3D G3DSA:3.40.1190.20 37 299 8.3E-35 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 PIRSF PIRSF000535 1 299 1.5E-70 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 Gene3D G3DSA:2.20.150.10 3 36 2.0E-10 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 SUPERFAMILY SSF53613 2 294 1.45E-57 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 1 297 8.5E-96 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CPF12_RS05145 4e6ae1565df0a364ea5b9a4c66d722e9 302 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 1 297 9.4E-97 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 SUPERFAMILY SSF51735 206 450 1.56E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 Gene3D G3DSA:3.40.50.720 213 376 5.3E-42 T 28-03-2018 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 Gene3D G3DSA:1.10.285.10 377 451 2.3E-30 T 28-03-2018 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 Gene3D G3DSA:1.10.285.10 9 65 0.0052 T 28-03-2018 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 206 449 1.9E-85 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 SMART SM00839 208 449 1.4E-87 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 125 138 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 60 188 3.2E-50 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 Gene3D G3DSA:3.40.50.10860 66 205 7.3E-54 T 28-03-2018 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 PIRSF PIRSF000185 25 451 1.0E-122 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 SUPERFAMILY SSF53223 10 200 2.91E-72 T 28-03-2018 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 239 259 7.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 375 386 7.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 197 219 7.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS04070 e40784cb6472c1ca3c3c01784247475d 451 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 117 131 7.5E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 250 5.0E-68 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 SUPERFAMILY SSF53067 6 252 5.18E-65 T 28-03-2018 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 Gene3D G3DSA:3.30.420.40 252 509 3.0E-63 T 28-03-2018 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 448 9.5E-38 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 SUPERFAMILY SSF53067 254 495 7.29E-67 T 28-03-2018 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 Gene3D G3DSA:3.30.420.40 3 251 5.4E-65 T 28-03-2018 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 506 1.8E-206 T 28-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CPF12_RS07915 1ed8f796e5526cd231da1db161cbf3d5 510 PIRSF PIRSF000538 4 500 1.7E-140 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 Pfam PF01416 tRNA pseudouridine synthase 144 247 3.5E-28 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 Pfam PF01416 tRNA pseudouridine synthase 6 105 6.4E-8 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 SUPERFAMILY SSF55120 1 250 1.73E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 Gene3D G3DSA:3.30.70.580 1 106 2.8E-29 T 28-03-2018 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 PIRSF PIRSF001430 1 252 4.9E-77 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 33.233 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 241 2.7E-58 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS06215 2e68cf74690e39efc5357debb7a16aa3 252 Gene3D G3DSA:3.30.70.660 107 245 3.6E-37 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS00760 1d9effcc556d989fe66833afe33b17df 279 Gene3D G3DSA:3.20.20.70 15 275 1.1E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS00760 1d9effcc556d989fe66833afe33b17df 279 SUPERFAMILY SSF51445 36 247 2.65E-20 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS00760 1d9effcc556d989fe66833afe33b17df 279 Pfam PF03537 Glycoside-hydrolase family GH114 35 253 5.6E-17 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CPF12_RS01850 6a9a0a97eec256079bcc8c66f97dfc1b 773 Gene3D G3DSA:3.90.1640.10 66 245 1.7E-26 T 28-03-2018 CPF12_RS01850 6a9a0a97eec256079bcc8c66f97dfc1b 773 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 33 562 1.0E-180 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CPF12_RS01850 6a9a0a97eec256079bcc8c66f97dfc1b 773 SUPERFAMILY SSF64182 60 446 6.41E-116 T 28-03-2018 CPF12_RS01850 6a9a0a97eec256079bcc8c66f97dfc1b 773 Pfam PF01368 DHH family 86 228 2.3E-11 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CPF12_RS01850 6a9a0a97eec256079bcc8c66f97dfc1b 773 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 767 2.9E-47 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CPF12_RS01850 6a9a0a97eec256079bcc8c66f97dfc1b 773 Pfam PF02272 DHHA1 domain 319 438 6.3E-20 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 405 528 2.0E-21 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 374 384 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 Pfam PF01266 FAD dependent oxidoreductase 23 353 3.1E-53 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 22 34 3.0E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 35 45 3.0E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 369 381 3.0E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 63 3.0E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 339 345 3.0E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 96 108 3.0E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 SUPERFAMILY SSF51905 16 240 4.28E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 Gene3D G3DSA:3.30.9.10 100 205 6.2E-8 T 28-03-2018 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 Gene3D G3DSA:3.30.9.10 206 346 4.1E-41 T 28-03-2018 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 SUPERFAMILY SSF54373 251 345 1.55E-11 T 28-03-2018 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 27 44 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CPF12_RS06845 52ecb9d368c424959873896522ea1b29 550 Gene3D G3DSA:3.50.50.60 3 90 2.6E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS03655 03c4b8be56308d6bbd6ae4889fad98ad 870 Pfam PF09586 Bacterial membrane protein YfhO 19 848 4.0E-227 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CPF12_RS02730 a22949dd17c6d05e2d246c0caf8900c2 60 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 3.1E-13 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 CPF12_RS03080 b3c907800d8940238bf92867928616f2 312 SUPERFAMILY SSF54593 4 288 3.0E-38 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03080 b3c907800d8940238bf92867928616f2 312 Gene3D G3DSA:3.10.180.10 2 151 1.9E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03080 b3c907800d8940238bf92867928616f2 312 Gene3D G3DSA:3.10.180.10 152 312 1.2E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03080 b3c907800d8940238bf92867928616f2 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 271 1.3E-21 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS10330 55ae78c19aceb01e2282ca2df557aa43 183 Gene3D G3DSA:3.10.450.40 120 182 8.3E-15 T 28-03-2018 CPF12_RS10330 55ae78c19aceb01e2282ca2df557aa43 183 Gene3D G3DSA:3.10.450.40 47 109 2.3E-15 T 28-03-2018 CPF12_RS10330 55ae78c19aceb01e2282ca2df557aa43 183 SUPERFAMILY SSF54403 51 103 2.72E-8 T 28-03-2018 CPF12_RS10330 55ae78c19aceb01e2282ca2df557aa43 183 SUPERFAMILY SSF54403 120 182 2.04E-15 T 28-03-2018 CPF12_RS01895 7cba0e14f85bccfe4da42fc446b6cded 147 Pfam PF03788 LrgA family 36 127 4.0E-25 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 PIRSF PIRSF038945 1 347 7.8E-157 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 Gene3D G3DSA:3.40.50.1100 37 143 3.9E-27 T 28-03-2018 CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 SUPERFAMILY SSF53686 5 340 1.27E-105 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 4.3E-79 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 Gene3D G3DSA:3.40.50.1100 144 332 8.7E-51 T 28-03-2018 CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 TIGRFAM TIGR00260 thrC: threonine synthase 8 322 7.6E-103 T 28-03-2018 IPR004450 Threonine synthase-like CPF12_RS09795 2dcde4f8b0da6406aa4e49ce5da78baa 351 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 Gene3D G3DSA:3.90.226.10 26 312 5.3E-66 T 28-03-2018 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 48.73 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 8.0E-65 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 5 317 3.1E-149 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.3E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.3E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.3E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.3E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.3E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.3E-47 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CPF12_RS08435 844db77e3b116b14dd9816825f05c161 318 SUPERFAMILY SSF52096 7 315 2.09E-96 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 578 4.1E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 SUPERFAMILY SSF55874 434 576 5.37E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 SMART SM00065 238 373 1.3E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 Pfam PF06580 Histidine kinase 378 456 1.9E-23 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 SMART SM00387 472 579 0.0027 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 Gene3D G3DSA:3.30.565.10 394 578 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00510 0afdd7855ec72e95c5926bf33377ee7f 584 Pfam PF07694 5TMR of 5TMR-LYT 26 207 4.1E-46 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 3.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 SUPERFAMILY SSF53850 79 279 2.5E-25 T 28-03-2018 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 Gene3D G3DSA:3.40.190.10 176 264 2.5E-10 T 28-03-2018 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 Gene3D G3DSA:1.10.10.10 1 89 1.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 Gene3D G3DSA:3.40.190.10 90 175 3.3E-12 T 28-03-2018 CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 Pfam PF03466 LysR substrate binding domain 89 276 8.0E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS11775 9e11995c1f65c3caa271ea8a4f8a2a0f 289 SUPERFAMILY SSF46785 5 85 1.47E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 172 185 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 Gene3D G3DSA:3.40.50.300 2 139 1.4E-41 T 28-03-2018 CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 SUPERFAMILY SSF52540 1 139 4.43E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 Gene3D G3DSA:3.30.60.20 140 189 2.1E-17 T 28-03-2018 CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 Pfam PF00265 Thymidine kinase 3 185 3.5E-47 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 PIRSF PIRSF035805 1 190 4.9E-58 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 Hamap MF_00124 Thymidine kinase [tdk]. 1 188 32.586 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CPF12_RS06430 22fd064c823ab36e9be8104bf2163044 190 SUPERFAMILY SSF57716 140 188 7.13E-16 T 28-03-2018 CPF12_RS09495 1b022a86edd773f0f56d74cdaf734841 249 Gene3D G3DSA:1.10.600.10 41 187 3.1E-6 T 28-03-2018 IPR008949 Isoprenoid synthase domain CPF12_RS09495 1b022a86edd773f0f56d74cdaf734841 249 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 28 224 6.6E-36 T 28-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CPF12_RS07070 9049192a23182a9572bca8c64bc4f0e3 190 Pfam PF03334 Na+/H+ antiporter subunit 15 97 3.0E-22 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CPF12_RS07070 9049192a23182a9572bca8c64bc4f0e3 190 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 14 111 3.5E-25 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CPF12_RS07070 9049192a23182a9572bca8c64bc4f0e3 190 Gene3D G3DSA:1.20.120.560 21 188 5.9E-4 T 28-03-2018 CPF12_RS12140 69af483d483376fbe1c98553b1b86eaa 323 Pfam PF00892 EamA-like transporter family 31 164 4.4E-24 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CPF12_RS12140 69af483d483376fbe1c98553b1b86eaa 323 Pfam PF00892 EamA-like transporter family 177 319 1.3E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CPF12_RS12140 69af483d483376fbe1c98553b1b86eaa 323 SUPERFAMILY SSF103481 241 321 4.84E-15 T 28-03-2018 CPF12_RS12140 69af483d483376fbe1c98553b1b86eaa 323 SUPERFAMILY SSF103481 66 166 1.24E-12 T 28-03-2018 CPF12_RS01135 29b21882bea242d945c1aa17851b0db5 193 SUPERFAMILY SSF52540 1 192 2.43E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01135 29b21882bea242d945c1aa17851b0db5 193 Gene3D G3DSA:3.40.50.300 8 70 3.5E-12 T 28-03-2018 CPF12_RS01135 29b21882bea242d945c1aa17851b0db5 193 Pfam PF01926 50S ribosome-binding GTPase 26 143 3.4E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS01135 29b21882bea242d945c1aa17851b0db5 193 Gene3D G3DSA:3.40.50.300 71 192 1.9E-14 T 28-03-2018 CPF12_RS01135 29b21882bea242d945c1aa17851b0db5 193 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 27.415 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CPF12_RS01135 29b21882bea242d945c1aa17851b0db5 193 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 2.9E-67 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CPF12_RS03605 8cf423175ff724003ac6b6f0a1f84cd0 621 SUPERFAMILY SSF51730 330 614 5.89E-69 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CPF12_RS03605 8cf423175ff724003ac6b6f0a1f84cd0 621 SUPERFAMILY SSF82282 2 371 5.76E-93 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CPF12_RS03605 8cf423175ff724003ac6b6f0a1f84cd0 621 Gene3D G3DSA:3.20.20.220 316 619 2.5E-64 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CPF12_RS03605 8cf423175ff724003ac6b6f0a1f84cd0 621 Gene3D G3DSA:3.20.20.330 1 315 2.1E-81 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CPF12_RS03605 8cf423175ff724003ac6b6f0a1f84cd0 621 Pfam PF02219 Methylenetetrahydrofolate reductase 330 598 8.1E-30 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CPF12_RS03605 8cf423175ff724003ac6b6f0a1f84cd0 621 Pfam PF02574 Homocysteine S-methyltransferase 13 290 7.0E-55 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 SUPERFAMILY SSF74942 84 151 1.96E-18 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 Gene3D G3DSA:2.30.30.180 87 149 1.6E-18 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 Gene3D G3DSA:3.30.300.70 1 80 2.6E-29 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 Pfam PF02576 RimP N-terminal domain 11 83 2.0E-29 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 Pfam PF17384 RimP C-terminal SH3 domain 86 151 1.6E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 24.677 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CPF12_RS12200 d301de66c372174de0d5d19e9e3a34bb 151 SUPERFAMILY SSF75420 2 83 2.22E-27 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Gene3D G3DSA:2.30.30.170 192 266 5.6E-9 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Gene3D G3DSA:2.30.30.170 20 112 3.6E-11 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 SUPERFAMILY SSF56601 271 506 4.12E-28 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Gene3D G3DSA:2.30.30.170 117 191 1.5E-11 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 SUPERFAMILY SSF82057 121 190 1.07E-9 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Pfam PF13457 SH3-like domain 203 264 2.2E-4 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Pfam PF13457 SH3-like domain 40 110 3.3E-7 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Pfam PF13457 SH3-like domain 125 190 7.0E-5 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Pfam PF13354 Beta-lactamase enzyme family 294 486 3.3E-26 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 SUPERFAMILY SSF82057 41 111 3.02E-10 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 SUPERFAMILY SSF82057 198 264 2.87E-8 T 28-03-2018 CPF12_RS00555 eeda2fcf4efc9b6a864fba3dc74caadc 509 Gene3D G3DSA:3.40.710.10 267 508 1.3E-13 T 28-03-2018 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 SMART SM00342 158 241 9.3E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 Gene3D G3DSA:1.10.10.60 209 247 2.4E-14 T 28-03-2018 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 Pfam PF00072 Response regulator receiver domain 4 116 2.1E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 Gene3D G3DSA:3.40.50.2300 1 118 1.2E-14 T 28-03-2018 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 SUPERFAMILY SSF46689 143 192 5.29E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 Pfam PF12833 Helix-turn-helix domain 164 243 3.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 SUPERFAMILY SSF52172 3 120 1.01E-16 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 241 4.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 210 225 4.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 SUPERFAMILY SSF46689 194 245 5.38E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS10870 f08437d06c071e64d4bd54137a964285 247 Gene3D G3DSA:3.90.1240.10 119 208 7.5E-28 T 28-03-2018 CPF12_RS03980 12f1028c1ab9d6c023a1ccd74ff981bd 223 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 14 214 5.6E-56 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CPF12_RS03980 12f1028c1ab9d6c023a1ccd74ff981bd 223 Pfam PF03070 TENA/THI-4/PQQC family 15 214 1.1E-45 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CPF12_RS03980 12f1028c1ab9d6c023a1ccd74ff981bd 223 SUPERFAMILY SSF48613 4 220 2.97E-63 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CPF12_RS03980 12f1028c1ab9d6c023a1ccd74ff981bd 223 Gene3D G3DSA:1.20.910.10 2 223 4.5E-53 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CPF12_RS00190 fcd10816c532fa12fb3468fd87dae5f9 164 SUPERFAMILY SSF143414 4 94 6.67E-24 T 28-03-2018 CPF12_RS00190 fcd10816c532fa12fb3468fd87dae5f9 164 Pfam PF00936 BMC domain 5 79 1.7E-21 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00190 fcd10816c532fa12fb3468fd87dae5f9 164 SMART SM00877 4 80 1.8E-25 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00190 fcd10816c532fa12fb3468fd87dae5f9 164 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 66 4.0E-11 T 28-03-2018 CPF12_RS00190 fcd10816c532fa12fb3468fd87dae5f9 164 Gene3D G3DSA:1.10.720.10 109 159 1.0E-6 T 28-03-2018 CPF12_RS08175 504280f10108f2ba32d05ee8643d3ab7 97 SUPERFAMILY SSF89360 1 85 1.31E-8 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS08175 504280f10108f2ba32d05ee8643d3ab7 97 Gene3D G3DSA:2.60.300.12 1 93 3.8E-7 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CPF12_RS08175 504280f10108f2ba32d05ee8643d3ab7 97 PIRSF PIRSF034852 1 94 6.6E-32 T 28-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CPF12_RS03140 3a067ff9f0962964c6260ba92492325c 337 SMART SM00829 10 330 6.1E-29 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CPF12_RS03140 3a067ff9f0962964c6260ba92492325c 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 3.1E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CPF12_RS03140 3a067ff9f0962964c6260ba92492325c 337 Pfam PF13602 Zinc-binding dehydrogenase 190 330 6.2E-25 T 28-03-2018 CPF12_RS03140 3a067ff9f0962964c6260ba92492325c 337 Gene3D G3DSA:3.90.180.10 1 333 1.6E-70 T 28-03-2018 CPF12_RS03140 3a067ff9f0962964c6260ba92492325c 337 SUPERFAMILY SSF51735 117 252 2.22E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03140 3a067ff9f0962964c6260ba92492325c 337 SUPERFAMILY SSF50129 1 150 4.57E-40 T 28-03-2018 IPR011032 GroES-like CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 SUPERFAMILY SSF51735 5 243 7.67E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 9.1E-68 T 28-03-2018 CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 Gene3D G3DSA:3.40.50.720 48 244 3.0E-60 T 28-03-2018 CPF12_RS07475 d893ac66cf8dbf2517231fff92535747 244 Gene3D G3DSA:3.40.50.720 1 47 7.4E-9 T 28-03-2018 CPF12_RS08860 f85b7496128657d40a4e00bb091f48ec 368 Pfam PF13477 Glycosyl transferase 4-like 3 143 8.8E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CPF12_RS08860 f85b7496128657d40a4e00bb091f48ec 368 SUPERFAMILY SSF53756 14 366 4.49E-60 T 28-03-2018 CPF12_RS08860 f85b7496128657d40a4e00bb091f48ec 368 Pfam PF00534 Glycosyl transferases group 1 189 346 2.8E-33 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CPF12_RS08860 f85b7496128657d40a4e00bb091f48ec 368 Gene3D G3DSA:3.40.50.2000 19 181 2.7E-11 T 28-03-2018 CPF12_RS08860 f85b7496128657d40a4e00bb091f48ec 368 Gene3D G3DSA:3.40.50.2000 185 352 2.7E-38 T 28-03-2018 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 16 170 2.1E-44 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 Pfam PF00717 Peptidase S24-like 38 100 4.4E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 Gene3D G3DSA:2.10.109.10 28 176 1.4E-36 T 28-03-2018 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 ProSitePatterns PS00761 Signal peptidases I signature 3. 134 147 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 32 48 3.3E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 129 148 3.3E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 3.3E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 ProSitePatterns PS00501 Signal peptidases I serine active site. 41 48 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CPF12_RS11790 ea4eda1f6d0b5712e0c84b89aec380f2 176 SUPERFAMILY SSF51306 30 175 1.44E-45 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 PIRSF PIRSF037228 1 924 3.2E-221 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 SUPERFAMILY SSF158745 554 913 1.31E-51 T 28-03-2018 CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 Pfam PF13575 Domain of unknown function (DUF4135) 89 461 1.3E-72 T 28-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 Pfam PF05147 Lanthionine synthetase C-like protein 578 915 1.4E-60 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 PRINTS PR01950 LanC-like protein superfamily signature 835 848 1.6E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 PRINTS PR01950 LanC-like protein superfamily signature 892 909 1.6E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 PRINTS PR01950 LanC-like protein superfamily signature 580 598 1.6E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 PRINTS PR01950 LanC-like protein superfamily signature 722 738 1.6E-8 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 SMART SM01260 577 920 5.6E-14 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CPF12_RS11670 f036b4113cd7f1e1ff4fbbdadd76ea04 924 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 17 910 4.6E-160 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CPF12_RS03725 e0c3bb0396457f60c1aa5388240f7119 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 1.9E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS03725 e0c3bb0396457f60c1aa5388240f7119 309 SUPERFAMILY SSF161098 91 286 5.89E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS03725 e0c3bb0396457f60c1aa5388240f7119 309 Gene3D G3DSA:1.10.3720.10 1 292 2.7E-32 T 28-03-2018 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 SUPERFAMILY SSF118215 12 400 5.89E-84 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 Gene3D G3DSA:1.10.3860.10 1 407 3.7E-84 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 224 243 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 190 209 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 143 165 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 2.6E-19 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS04155 9ec1aa02da63b62789df9f3856e68b1c 417 Pfam PF00375 Sodium:dicarboxylate symporter family 13 400 1.4E-94 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS08630 a181f631410aaf278021d10be4f7ebf4 292 SUPERFAMILY SSF50182 127 187 2.29E-13 T 28-03-2018 IPR010920 LSM domain CPF12_RS08630 a181f631410aaf278021d10be4f7ebf4 292 Gene3D G3DSA:3.30.70.100 191 284 6.4E-5 T 28-03-2018 CPF12_RS08630 a181f631410aaf278021d10be4f7ebf4 292 SUPERFAMILY SSF82689 190 282 1.57E-6 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CPF12_RS08630 a181f631410aaf278021d10be4f7ebf4 292 Gene3D G3DSA:2.30.30.60 142 190 3.8E-12 T 28-03-2018 CPF12_RS08630 a181f631410aaf278021d10be4f7ebf4 292 SUPERFAMILY SSF82861 39 125 7.72E-15 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CPF12_RS08630 a181f631410aaf278021d10be4f7ebf4 292 Pfam PF00924 Mechanosensitive ion channel 84 278 6.0E-40 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 Gene3D G3DSA:3.40.50.300 327 581 1.5E-62 T 28-03-2018 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 SMART SM00382 367 552 5.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 Pfam PF00005 ABC transporter 359 505 1.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 Gene3D G3DSA:1.20.1560.10 4 317 5.4E-27 T 28-03-2018 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 SUPERFAMILY SSF90123 6 316 1.05E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 5 536 9.8E-163 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CPF12_RS05620 50eb1b5f136d47ea95b59ab22beb9a7a 584 SUPERFAMILY SSF52540 334 575 2.15E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10605 08d9f0d31e4de9faa28e72f0a391400f 201 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 14 196 1.1E-43 T 28-03-2018 IPR018672 Protein of unknown function DUF2140 CPF12_RS11955 0e8ff3226d8896fec6f8f401067e8d37 251 Pfam PF01061 ABC-2 type transporter 25 219 5.8E-10 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CPF12_RS11665 92eae28ee607a467e8ca9fabe2c7f17e 412 SMART SM00387 305 411 3.3E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11665 92eae28ee607a467e8ca9fabe2c7f17e 412 SUPERFAMILY SSF55874 276 410 1.96E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11665 92eae28ee607a467e8ca9fabe2c7f17e 412 Gene3D G3DSA:1.10.287.130 203 263 1.4E-5 T 28-03-2018 CPF12_RS11665 92eae28ee607a467e8ca9fabe2c7f17e 412 Pfam PF14501 GHKL domain 310 409 5.1E-15 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CPF12_RS11665 92eae28ee607a467e8ca9fabe2c7f17e 412 Gene3D G3DSA:3.30.565.10 264 412 2.6E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS07965 85d6e9683bd0cb463ee0f092a5bd64a1 361 SUPERFAMILY SSF56059 177 355 7.46E-12 T 28-03-2018 CPF12_RS07965 85d6e9683bd0cb463ee0f092a5bd64a1 361 Gene3D G3DSA:3.30.470.20 232 350 2.0E-7 T 28-03-2018 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Gene3D G3DSA:3.30.300.10 13 145 1.4E-43 T 28-03-2018 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 7.8E-48 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 58.091 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Gene3D G3DSA:3.30.300.10 260 398 4.5E-46 T 28-03-2018 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 396 1.0E-182 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 SUPERFAMILY SSF55973 247 396 5.1E-69 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 102 1.0E-43 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 PIRSF PIRSF000497 1 398 5.1E-177 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Gene3D G3DSA:3.30.300.10 146 247 3.5E-46 T 28-03-2018 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 1.1E-68 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 SUPERFAMILY SSF55973 5 111 2.83E-47 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS11140 113c5f5cb580954221c1ee6af15845b7 398 SUPERFAMILY SSF55973 125 246 1.37E-50 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.63 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.1E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.2E-63 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 SUPERFAMILY SSF54747 1 84 1.57E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 SMART SM00649 9 140 3.0E-86 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 SUPERFAMILY SSF46906 67 140 9.68E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 4.0E-15 T 28-03-2018 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 Gene3D G3DSA:3.30.1550.10 3 71 6.7E-36 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 4.3E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CPF12_RS05995 d47366049516f1cae6b901773561dc74 141 Gene3D G3DSA:1.10.10.250 72 140 6.9E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CPF12_RS00970 e020aaf3d88216e8d12b68c508b885b8 103 Pfam PF06279 Protein of unknown function (DUF1033) 4 95 1.7E-27 T 28-03-2018 IPR010434 Protein of unknown function DUF1033 CPF12_RS01985 4c70718f6b06044d1c5a68711053b74e 93 Pfam PF02325 YGGT family 12 76 4.7E-22 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CPF12_RS04080 41cb136760aaa0705ee373950ae06cdf 252 Gene3D G3DSA:3.40.50.300 1 252 3.8E-62 T 28-03-2018 CPF12_RS04080 41cb136760aaa0705ee373950ae06cdf 252 SUPERFAMILY SSF52540 5 226 2.97E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04080 41cb136760aaa0705ee373950ae06cdf 252 Pfam PF00005 ABC transporter 26 174 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04080 41cb136760aaa0705ee373950ae06cdf 252 SMART SM00382 35 223 3.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03705 957bfb3352ceac1961507b0aa5180ae5 554 SUPERFAMILY SSF53850 35 549 1.33E-106 T 28-03-2018 CPF12_RS03705 957bfb3352ceac1961507b0aa5180ae5 554 Gene3D G3DSA:3.90.76.10 48 208 1.1E-36 T 28-03-2018 CPF12_RS03705 957bfb3352ceac1961507b0aa5180ae5 554 Gene3D G3DSA:3.40.190.10 209 305 4.9E-20 T 28-03-2018 CPF12_RS03705 957bfb3352ceac1961507b0aa5180ae5 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 472 1.3E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CPF12_RS03705 957bfb3352ceac1961507b0aa5180ae5 554 Gene3D G3DSA:3.10.105.10 306 525 1.1E-40 T 28-03-2018 CPF12_RS03705 957bfb3352ceac1961507b0aa5180ae5 554 PIRSF PIRSF002741 1 554 7.4E-89 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 346 1.3E-141 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 SUPERFAMILY SSF53659 4 347 1.27E-113 T 28-03-2018 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 SMART SM01329 4 343 6.8E-175 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 Gene3D G3DSA:3.40.718.10 1 351 3.7E-119 T 28-03-2018 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 346 3.6E-125 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 347 45.285 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CPF12_RS01925 5f3f58193200e8bef3d8b84e52f960e8 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 Gene3D G3DSA:2.160.10.10 1 185 1.4E-49 T 28-03-2018 CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 95 110 0.047 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 165 6.1E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 Pfam PF12464 Maltose acetyltransferase 7 56 1.1E-14 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 SUPERFAMILY SSF51161 2 184 1.8E-51 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS03170 9adae8baed0f2874aa64d2a5aff64b5a 185 SMART SM01266 5 58 2.7E-19 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CPF12_RS00175 0a0fcc42cf5a61d1013ff88c1757230e 211 Pfam PF06130 Phosphate propanoyltransferase 132 196 2.6E-19 T 28-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CPF12_RS00175 0a0fcc42cf5a61d1013ff88c1757230e 211 Pfam PF06130 Phosphate propanoyltransferase 23 102 2.3E-26 T 28-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CPF12_RS00175 0a0fcc42cf5a61d1013ff88c1757230e 211 PIRSF PIRSF010130 1 209 3.3E-88 T 28-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 CPF12_RS10875 3f729655607c358d1be1bbf352447df4 446 Pfam PF00171 Aldehyde dehydrogenase family 9 271 2.1E-21 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS10875 3f729655607c358d1be1bbf352447df4 446 Gene3D G3DSA:3.40.605.10 4 228 2.1E-28 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS10875 3f729655607c358d1be1bbf352447df4 446 SUPERFAMILY SSF53720 9 445 1.68E-73 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS10875 3f729655607c358d1be1bbf352447df4 446 Gene3D G3DSA:3.40.309.10 229 403 2.3E-22 T 28-03-2018 CPF12_RS04960 fca73a61d711271c6e979041a013de3f 259 Gene3D G3DSA:3.20.20.190 30 251 1.1E-20 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS04960 fca73a61d711271c6e979041a013de3f 259 SUPERFAMILY SSF51695 47 234 7.33E-17 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS08075 38246699d49db5a3e8252bf6c0f4db0f 357 Gene3D G3DSA:3.40.640.10 31 248 1.3E-28 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS08075 38246699d49db5a3e8252bf6c0f4db0f 357 Pfam PF01212 Beta-eliminating lyase 39 283 3.0E-37 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CPF12_RS08075 38246699d49db5a3e8252bf6c0f4db0f 357 SUPERFAMILY SSF53383 35 310 3.66E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS02310 bf95e4b05089e9c260c85a8dfa79cb60 249 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 232 2.0E-77 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02310 bf95e4b05089e9c260c85a8dfa79cb60 249 Gene3D G3DSA:3.40.1160.10 1 241 1.5E-50 T 28-03-2018 CPF12_RS02310 bf95e4b05089e9c260c85a8dfa79cb60 249 PIRSF PIRSF000728 1 248 8.0E-82 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02310 bf95e4b05089e9c260c85a8dfa79cb60 249 SUPERFAMILY SSF53633 3 245 6.94E-63 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS02310 bf95e4b05089e9c260c85a8dfa79cb60 249 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 245 28.558 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CPF12_RS02310 bf95e4b05089e9c260c85a8dfa79cb60 249 Pfam PF00696 Amino acid kinase family 4 234 8.4E-46 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 1.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 1.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 1.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 1.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 1.1E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 Gene3D G3DSA:3.30.420.40 148 292 1.5E-16 T 28-03-2018 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 317 1.0E-131 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 337 61.78 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 Pfam PF00814 Glycoprotease family 27 312 2.4E-104 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 SUPERFAMILY SSF53067 6 126 1.23E-31 T 28-03-2018 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 SUPERFAMILY SSF53067 105 313 2.16E-40 T 28-03-2018 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 312 4.0E-110 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CPF12_RS02270 97fe9e669b3ec898f02440aac9fd5b82 340 Gene3D G3DSA:3.30.420.40 5 147 2.3E-42 T 28-03-2018 CPF12_RS00810 3762f70bd3147b8a0d1ff111a84f35b7 109 Pfam PF13108 Protein of unknown function (DUF3969) 1 54 4.5E-6 T 28-03-2018 IPR025083 Protein of unknown function DUF3969 CPF12_RS07065 fd961e150089ef55c70ce7451d97f856 159 Gene3D G3DSA:1.20.144.10 2 159 1.3E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CPF12_RS07065 fd961e150089ef55c70ce7451d97f856 159 Pfam PF02681 Divergent PAP2 family 5 149 2.0E-49 T 28-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 Gene3D G3DSA:3.40.50.10490 62 207 1.3E-41 T 28-03-2018 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 Gene3D G3DSA:3.40.50.10490 208 434 4.4E-74 T 28-03-2018 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 3.1E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 3.1E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 3.1E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 3.1E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 3.1E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 3.1E-26 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 25.326 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 Pfam PF00342 Phosphoglucose isomerase 76 425 6.6E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 SUPERFAMILY SSF53697 4 447 2.91E-138 T 28-03-2018 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS07125 905e9d9b4a4dee3bccf59c18daa9b93f 450 Gene3D G3DSA:3.40.50.10490 1 61 3.7E-12 T 28-03-2018 CPF12_RS02630 dc22cc618e101cf41883dd4fb975e7ab 253 Gene3D G3DSA:3.40.30.10 3 189 4.3E-16 T 28-03-2018 CPF12_RS02630 dc22cc618e101cf41883dd4fb975e7ab 253 Pfam PF13743 Thioredoxin 22 57 6.3E-8 T 28-03-2018 CPF12_RS02630 dc22cc618e101cf41883dd4fb975e7ab 253 Pfam PF13743 Thioredoxin 75 181 1.8E-31 T 28-03-2018 CPF12_RS02630 dc22cc618e101cf41883dd4fb975e7ab 253 SUPERFAMILY SSF52833 18 189 1.01E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS04490 57af9c184175183dd9990d59c7b42fce 235 Gene3D G3DSA:1.10.3720.10 3 232 7.1E-28 T 28-03-2018 CPF12_RS04490 57af9c184175183dd9990d59c7b42fce 235 SUPERFAMILY SSF161098 14 216 2.75E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04490 57af9c184175183dd9990d59c7b42fce 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 228 2.8E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 1.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 SUPERFAMILY SSF51905 1 318 6.48E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 Gene3D G3DSA:3.50.50.60 200 338 5.3E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 Hamap MF_01685 Ferredoxin--NADP reductase. 5 331 35.006 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.9E-15 T 28-03-2018 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.9E-15 T 28-03-2018 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 3.9E-15 T 28-03-2018 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 Gene3D G3DSA:3.50.50.60 5 199 1.1E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 2.1E-20 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 2.1E-20 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 2.1E-20 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS04110 213c4e923e82916958f858c129c7ce28 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 2.1E-20 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CPF12_RS02860 8c7533a116eb371e517999af09b2c4ef 117 Gene3D G3DSA:1.20.5.50 22 117 1.7E-4 T 28-03-2018 CPF12_RS02860 8c7533a116eb371e517999af09b2c4ef 117 Pfam PF12732 YtxH-like protein 8 93 9.1E-15 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH CPF12_RS00050 cf70a02830d65d815fdef17c1aaf6e84 212 SUPERFAMILY SSF52317 1 176 7.2E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00050 cf70a02830d65d815fdef17c1aaf6e84 212 Gene3D G3DSA:3.40.50.880 1 208 4.8E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00050 cf70a02830d65d815fdef17c1aaf6e84 212 Pfam PF01965 DJ-1/PfpI family 2 173 5.8E-24 T 28-03-2018 IPR002818 DJ-1/PfpI CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 Pfam PF01979 Amidohydrolase family 50 424 5.9E-44 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 428 42.93 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 306 317 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 SUPERFAMILY SSF51556 54 372 2.88E-101 T 28-03-2018 IPR032466 Metal-dependent hydrolase CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 426 6.4E-130 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 Gene3D G3DSA:3.20.20.140 59 417 1.2E-102 T 28-03-2018 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 SUPERFAMILY SSF51338 2 53 5.71E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 SUPERFAMILY SSF51338 370 427 5.71E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS11325 4df89d50c778509288e757ee26ad3f92 428 Gene3D G3DSA:2.30.40.10 1 58 3.8E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CPF12_RS03005 525549a6bfd099a8b6016e0f6036555b 394 Gene3D G3DSA:1.20.1250.20 198 394 1.5E-19 T 28-03-2018 CPF12_RS03005 525549a6bfd099a8b6016e0f6036555b 394 Pfam PF07690 Major Facilitator Superfamily 16 327 6.4E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS03005 525549a6bfd099a8b6016e0f6036555b 394 SUPERFAMILY SSF103473 9 387 8.37E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS03005 525549a6bfd099a8b6016e0f6036555b 394 Gene3D G3DSA:1.20.1250.20 4 197 3.6E-30 T 28-03-2018 CPF12_RS03680 75277109fbdc0a2c7b9862c3f58a4284 70 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 12 68 1.9E-10 T 28-03-2018 IPR018690 Protein of unknown function DUF2187 CPF12_RS04295 c40875b0234ccc6f0f72d615d2b0b0d7 128 SUPERFAMILY SSF52374 1 124 1.1E-33 T 28-03-2018 CPF12_RS04295 c40875b0234ccc6f0f72d615d2b0b0d7 128 Pfam PF01467 Cytidylyltransferase-like 5 123 1.4E-21 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS04295 c40875b0234ccc6f0f72d615d2b0b0d7 128 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 2.3E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CPF12_RS04295 c40875b0234ccc6f0f72d615d2b0b0d7 128 Gene3D G3DSA:3.40.50.620 1 127 5.7E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS04295 c40875b0234ccc6f0f72d615d2b0b0d7 128 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 1.8E-62 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 CPF12_RS05465 bf0bc9fa1d997088ff71e0d97e9a038a 238 Gene3D G3DSA:3.40.50.150 2 238 9.0E-36 T 28-03-2018 CPF12_RS05465 bf0bc9fa1d997088ff71e0d97e9a038a 238 Pfam PF02527 rRNA small subunit methyltransferase G 22 200 1.6E-55 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CPF12_RS05465 bf0bc9fa1d997088ff71e0d97e9a038a 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 216 1.7E-50 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CPF12_RS05465 bf0bc9fa1d997088ff71e0d97e9a038a 238 PIRSF PIRSF003078 3 220 2.9E-52 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CPF12_RS05465 bf0bc9fa1d997088ff71e0d97e9a038a 238 SUPERFAMILY SSF53335 3 236 5.14E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS05465 bf0bc9fa1d997088ff71e0d97e9a038a 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.83 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CPF12_RS03875 026851e5979cabb7a39de4722876d3b8 329 Gene3D G3DSA:3.40.50.10440 11 183 1.9E-71 T 28-03-2018 CPF12_RS03875 026851e5979cabb7a39de4722876d3b8 329 SUPERFAMILY SSF82549 1 328 8.11E-121 T 28-03-2018 CPF12_RS03875 026851e5979cabb7a39de4722876d3b8 329 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 328 2.2E-147 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CPF12_RS03875 026851e5979cabb7a39de4722876d3b8 329 Gene3D G3DSA:3.30.1180.20 184 329 8.1E-43 T 28-03-2018 CPF12_RS03875 026851e5979cabb7a39de4722876d3b8 329 Pfam PF02733 Dak1 domain 17 325 5.8E-117 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 SUPERFAMILY SSF63520 57 158 4.45E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 SUPERFAMILY SSF50151 1 52 9.42E-14 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 Gene3D G3DSA:2.30.24.10 2 45 1.1E-16 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 Pfam PF00874 PRD domain 178 269 1.1E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 Pfam PF00874 PRD domain 73 158 8.0E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 Pfam PF03123 CAT RNA binding domain 1 54 2.5E-16 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 SMART SM01061 1 59 5.2E-13 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 SUPERFAMILY SSF63520 169 270 9.29E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 Gene3D G3DSA:1.10.1790.10 161 272 1.3E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS04385 001eef0d3f398be82ccf7a95cca25a16 272 Gene3D G3DSA:1.10.1790.10 46 159 5.6E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS01345 436c7913b22570b8b9d274e1c3eab8c1 166 Pfam PF07681 DoxX 15 114 9.4E-10 T 28-03-2018 IPR032808 DoxX family CPF12_RS04800 09a939f0efdd60f9b50124eb02656ded 539 Gene3D G3DSA:1.10.10.10 128 183 0.016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04800 09a939f0efdd60f9b50124eb02656ded 539 Pfam PF05043 Mga helix-turn-helix domain 115 196 1.5E-14 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS04800 09a939f0efdd60f9b50124eb02656ded 539 Gene3D G3DSA:1.10.10.10 44 118 2.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09325 5a2cf01a6e4394d58a26f493abdbf18f 335 Hamap MF_01562 UPF0365 protein . 6 326 48.61 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CPF12_RS09325 5a2cf01a6e4394d58a26f493abdbf18f 335 Gene3D G3DSA:1.10.287.40 191 299 9.6E-4 T 28-03-2018 CPF12_RS09325 5a2cf01a6e4394d58a26f493abdbf18f 335 Pfam PF12127 SigmaW regulon antibacterial 12 322 1.4E-163 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CPF12_RS00795 040837734d0b337eecb0f9cfe8d49783 237 Gene3D G3DSA:3.40.50.300 1 232 2.5E-55 T 28-03-2018 CPF12_RS00795 040837734d0b337eecb0f9cfe8d49783 237 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00795 040837734d0b337eecb0f9cfe8d49783 237 SMART SM00382 27 199 2.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00795 040837734d0b337eecb0f9cfe8d49783 237 SUPERFAMILY SSF52540 1 225 2.38E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00795 040837734d0b337eecb0f9cfe8d49783 237 Pfam PF00005 ABC transporter 19 161 3.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS09460 d52132d15f9def54e29d106c0b39eddb 234 SMART SM00257 183 231 3.2E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS09460 d52132d15f9def54e29d106c0b39eddb 234 Gene3D G3DSA:1.20.1000.10 2 182 4.3E-4 T 28-03-2018 CPF12_RS09460 d52132d15f9def54e29d106c0b39eddb 234 SUPERFAMILY SSF54106 183 231 6.67E-7 T 28-03-2018 IPR018392 LysM domain CPF12_RS09460 d52132d15f9def54e29d106c0b39eddb 234 Pfam PF01476 LysM domain 184 231 1.1E-9 T 28-03-2018 IPR018392 LysM domain CPF12_RS09460 d52132d15f9def54e29d106c0b39eddb 234 Gene3D G3DSA:3.10.350.10 183 234 1.2E-12 T 28-03-2018 CPF12_RS07775 5ea15f8f813bc975b6a5fdc6ed3ad8bf 154 Gene3D G3DSA:3.90.79.10 4 134 5.0E-19 T 28-03-2018 CPF12_RS07775 5ea15f8f813bc975b6a5fdc6ed3ad8bf 154 SUPERFAMILY SSF55811 5 97 9.61E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CPF12_RS07775 5ea15f8f813bc975b6a5fdc6ed3ad8bf 154 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CPF12_RS07775 5ea15f8f813bc975b6a5fdc6ed3ad8bf 154 PRINTS PR00502 NUDIX hydrolase family signature 29 43 3.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CPF12_RS07775 5ea15f8f813bc975b6a5fdc6ed3ad8bf 154 PRINTS PR00502 NUDIX hydrolase family signature 43 58 3.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CPF12_RS07775 5ea15f8f813bc975b6a5fdc6ed3ad8bf 154 Pfam PF00293 NUDIX domain 9 98 8.9E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 SUPERFAMILY SSF89447 1 136 4.6E-51 T 28-03-2018 CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 5.9E-53 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 1.0E-58 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 57.38 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 2.1E-23 T 28-03-2018 IPR020603 MraZ domain CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 2.1E-22 T 28-03-2018 IPR020603 MraZ domain CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 Gene3D G3DSA:2.10.260.10 1 62 3.7E-5 T 28-03-2018 CPF12_RS02050 211ed40642170b602eeb66293f887de0 143 Gene3D G3DSA:2.10.260.10 74 123 2.3E-4 T 28-03-2018 CPF12_RS06775 d6738faefa52ffa6e659c92a1f15549a 273 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 133 145 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CPF12_RS06775 d6738faefa52ffa6e659c92a1f15549a 273 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 7 257 9.3E-79 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CPF12_RS06775 d6738faefa52ffa6e659c92a1f15549a 273 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 4 262 17.837 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CPF12_RS06775 d6738faefa52ffa6e659c92a1f15549a 273 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 258 4.5E-80 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 Pfam PF13193 AMP-binding enzyme C-terminal domain 382 452 7.5E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 Gene3D G3DSA:3.40.50.980 11 158 1.5E-13 T 28-03-2018 CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 Gene3D G3DSA:3.40.50.980 159 310 1.3E-15 T 28-03-2018 CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 Gene3D G3DSA:3.30.300.30 367 469 5.2E-18 T 28-03-2018 CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 Pfam PF00501 AMP-binding enzyme 27 370 3.0E-24 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 ProSitePatterns PS00455 Putative AMP-binding domain signature. 152 163 - T 28-03-2018 IPR020845 AMP-binding, conserved site CPF12_RS08780 779cdae25b013e13d36486cf3a6eeb10 470 SUPERFAMILY SSF56801 28 461 1.03E-60 T 28-03-2018 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 Gene3D G3DSA:1.20.5.40 107 125 1.2E-14 T 28-03-2018 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 SMART SM00857 2 136 3.3E-51 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 Pfam PF00239 Resolvase, N terminal domain 2 135 1.8E-41 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 Pfam PF02796 Helix-turn-helix domain of resolvase 139 181 7.7E-6 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 Gene3D G3DSA:3.40.50.1390 1 106 9.8E-34 T 28-03-2018 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 Gene3D G3DSA:1.10.10.60 126 182 2.7E-7 T 28-03-2018 CPF12_RS12055 0243ff241f7535bbc6931dad01e34438 197 SUPERFAMILY SSF53041 1 135 1.14E-41 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS04725 27460611373d563ff06bdd2d075243e2 144 Pfam PF13673 Acetyltransferase (GNAT) domain 47 144 8.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS04725 27460611373d563ff06bdd2d075243e2 144 Gene3D G3DSA:3.40.630.30 1 144 3.5E-18 T 28-03-2018 CPF12_RS04725 27460611373d563ff06bdd2d075243e2 144 SUPERFAMILY SSF55729 1 143 3.12E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 383 101.786 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 371 6.5E-124 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 Gene3D G3DSA:3.40.50.300 1 370 8.9E-31 T 28-03-2018 CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 SUPERFAMILY SSF52540 1 217 1.97E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 SUPERFAMILY SSF52540 248 347 1.97E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 ProSitePatterns PS00618 RecF protein signature 2. 316 334 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CPF12_RS05525 af8526914ca1cb1f8ecbd06d4f45039a 383 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 349 3.2E-17 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CPF12_RS01630 f629445e3187133b42485d045922bd5f 73 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 55 5.9E-24 T 28-03-2018 IPR009256 Protein of unknown function DUF910 CPF12_RS01630 f629445e3187133b42485d045922bd5f 73 SUPERFAMILY SSF158379 1 58 1.02E-19 T 28-03-2018 IPR023164 YqgQ-like domain CPF12_RS01630 f629445e3187133b42485d045922bd5f 73 Gene3D G3DSA:1.10.287.760 1 65 2.2E-25 T 28-03-2018 IPR023164 YqgQ-like domain CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 SUPERFAMILY SSF55604 8 81 4.32E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 Pfam PF02378 Phosphotransferase system, EIIC 113 387 2.6E-23 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 475 599 4.1E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 5 621 6.9E-189 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 476 596 1.4E-42 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 Pfam PF00367 phosphotransferase system, EIIB 11 43 1.3E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 SUPERFAMILY SSF51261 470 621 1.92E-52 T 28-03-2018 IPR011055 Duplicated hybrid motif CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 Gene3D G3DSA:2.70.70.10 467 622 3.8E-55 T 28-03-2018 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 Gene3D G3DSA:3.30.1360.60 4 78 7.7E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04380 9ce38788cfaae598ed46490e734b6add 622 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 538 550 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CPF12_RS12320 41c0c4b2ef790745448dfc57c14c3949 262 Pfam PF01148 Cytidylyltransferase family 2 259 6.0E-62 T 28-03-2018 CPF12_RS12320 41c0c4b2ef790745448dfc57c14c3949 262 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 221 247 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 PIRSF PIRSF006728 1 415 1.5E-151 T 28-03-2018 IPR008135 Competence-induced protein CinA CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 Pfam PF02464 Competence-damaged protein 257 408 2.6E-50 T 28-03-2018 IPR008136 CinA, C-terminal CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 265 407 3.6E-33 T 28-03-2018 IPR008136 CinA, C-terminal CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 SMART SM00852 4 171 1.2E-36 T 28-03-2018 IPR001453 MoaB/Mog domain CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 166 3.5E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 Gene3D G3DSA:3.40.980.10 1 172 4.0E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 418 153.828 T 28-03-2018 IPR008135 Competence-induced protein CinA CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 SUPERFAMILY SSF53218 1 206 8.77E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 Gene3D G3DSA:3.90.950.20 247 414 1.7E-55 T 28-03-2018 CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 SUPERFAMILY SSF142433 250 410 9.42E-48 T 28-03-2018 IPR008136 CinA, C-terminal CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 Pfam PF00994 Probable molybdopterin binding domain 5 170 1.3E-32 T 28-03-2018 IPR001453 MoaB/Mog domain CPF12_RS00015 371d64d569cb9b1ead4012ddb0a43e24 418 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 411 8.3E-125 T 28-03-2018 IPR008135 Competence-induced protein CinA CPF12_RS07730 1daff4a9f86cc7fed3e84d52d640e38f 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 276 9.1E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07730 1daff4a9f86cc7fed3e84d52d640e38f 284 SUPERFAMILY SSF161098 12 284 1.59E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07730 1daff4a9f86cc7fed3e84d52d640e38f 284 Gene3D G3DSA:1.10.3720.10 5 271 2.7E-41 T 28-03-2018 CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 Gene3D G3DSA:3.30.1330.30 1 96 3.0E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 98 1.2E-6 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 SUPERFAMILY SSF55315 3 97 1.04E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 SMART SM00967 31 100 1.7E-5 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 SUPERFAMILY SSF75217 99 252 7.19E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 Pfam PF00588 SpoU rRNA Methylase family 108 249 8.7E-38 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CPF12_RS02385 8010d0b6cc2a68d97f4bf7d30ff33e4c 260 Gene3D G3DSA:3.40.1280.10 104 260 1.5E-43 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CPF12_RS08240 554e91c02c8ff3161e781b551e56e006 88 SUPERFAMILY SSF46955 38 85 2.56E-8 T 28-03-2018 IPR009061 Putative DNA-binding domain CPF12_RS08240 554e91c02c8ff3161e781b551e56e006 88 Gene3D G3DSA:1.10.10.10 50 88 1.6E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08240 554e91c02c8ff3161e781b551e56e006 88 Gene3D G3DSA:1.10.10.60 1 49 3.6E-4 T 28-03-2018 CPF12_RS12370 9b0c35f24c7356fb20b0227f477ad34c 1030 Pfam PF13476 AAA domain 6 214 7.4E-28 T 28-03-2018 CPF12_RS12370 9b0c35f24c7356fb20b0227f477ad34c 1030 Gene3D G3DSA:3.40.50.300 718 1019 1.7E-19 T 28-03-2018 CPF12_RS12370 9b0c35f24c7356fb20b0227f477ad34c 1030 Pfam PF13558 Putative exonuclease SbcCD, C subunit 925 987 1.1E-12 T 28-03-2018 CPF12_RS12370 9b0c35f24c7356fb20b0227f477ad34c 1030 Gene3D G3DSA:3.40.50.300 1 255 1.6E-25 T 28-03-2018 CPF12_RS12370 9b0c35f24c7356fb20b0227f477ad34c 1030 SUPERFAMILY SSF52540 1 222 2.05E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12370 9b0c35f24c7356fb20b0227f477ad34c 1030 SUPERFAMILY SSF52540 802 1017 2.05E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04245 cce2a2ea2339743f401348cbaf7d778f 466 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 403 420 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04245 cce2a2ea2339743f401348cbaf7d778f 466 Gene3D G3DSA:3.30.1360.60 386 460 3.6E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04245 cce2a2ea2339743f401348cbaf7d778f 466 SUPERFAMILY SSF55604 392 463 9.42E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04245 cce2a2ea2339743f401348cbaf7d778f 466 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 355 450 4.4E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS04245 cce2a2ea2339743f401348cbaf7d778f 466 Pfam PF00367 phosphotransferase system, EIIB 393 425 1.1E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS04245 cce2a2ea2339743f401348cbaf7d778f 466 Pfam PF02378 Phosphotransferase system, EIIC 9 297 2.2E-58 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 2.0E-53 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 SUPERFAMILY SSF74982 5 132 7.85E-54 T 28-03-2018 IPR023620 Small protein B CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 Gene3D G3DSA:2.40.280.10 9 127 3.2E-52 T 28-03-2018 IPR023620 Small protein B CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 4.9E-59 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 Pfam PF01668 SmpB protein 9 150 3.0E-63 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 76.761 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CPF12_RS07585 03b6fa71ad175c7e907d6e0b5965045f 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 Pfam PF00849 RNA pseudouridylate synthase 62 196 4.3E-26 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 Pfam PF01479 S4 domain 2 48 3.6E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 Gene3D G3DSA:3.10.290.10 1 70 3.2E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 2.3E-51 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 SUPERFAMILY SSF55120 46 237 1.19E-49 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 SUPERFAMILY SSF55174 2 67 1.96E-16 T 28-03-2018 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 Gene3D G3DSA:3.30.2350.10 71 242 6.9E-46 T 28-03-2018 CPF12_RS09410 11a4fa9e6305e6e24d42daa2c5cbc3b4 242 SMART SM00363 2 59 1.4E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS01530 47afb0704c43c681f1903b89353b387f 262 Gene3D G3DSA:3.60.110.10 1 259 2.3E-80 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CPF12_RS01530 47afb0704c43c681f1903b89353b387f 262 SUPERFAMILY SSF56317 1 260 9.29E-76 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CPF12_RS01530 47afb0704c43c681f1903b89353b387f 262 Pfam PF00795 Carbon-nitrogen hydrolase 3 244 8.3E-48 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CPF12_RS01055 b05a914f31d1040e880be2ed5401799e 301 Pfam PF00892 EamA-like transporter family 8 148 2.2E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CPF12_RS01055 b05a914f31d1040e880be2ed5401799e 301 Pfam PF00892 EamA-like transporter family 159 289 5.8E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CPF12_RS01055 b05a914f31d1040e880be2ed5401799e 301 SUPERFAMILY SSF103481 42 149 4.77E-13 T 28-03-2018 CPF12_RS01055 b05a914f31d1040e880be2ed5401799e 301 SUPERFAMILY SSF103481 189 290 2.09E-8 T 28-03-2018 CPF12_RS01055 b05a914f31d1040e880be2ed5401799e 301 TIGRFAM TIGR00688 rarD: protein RarD 8 266 5.7E-72 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CPF12_RS06240 9bba57247264002422f35020a365b8b2 205 Pfam PF00753 Metallo-beta-lactamase superfamily 12 171 2.4E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS06240 9bba57247264002422f35020a365b8b2 205 SMART SM00849 13 188 3.5E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS06240 9bba57247264002422f35020a365b8b2 205 Gene3D G3DSA:3.60.15.10 1 205 4.3E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS06240 9bba57247264002422f35020a365b8b2 205 SUPERFAMILY SSF56281 6 205 1.07E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 SUPERFAMILY SSF63999 10 119 5.62E-33 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 Gene3D G3DSA:3.40.50.10240 4 106 8.5E-26 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 12 106 2.3E-22 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 SUPERFAMILY SSF63862 123 198 2.09E-7 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 135 195 3.5E-12 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 10 197 5.4E-56 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 Gene3D G3DSA:2.60.120.320 107 202 7.0E-19 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS11485 098598ffa276761dca71389e2a5dc8a8 202 SMART SM00983 131 196 5.9E-20 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CPF12_RS04845 d8bf7a27a6a5efcbe1280d0c16ab9ff3 202 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 117 172 3.7E-7 T 28-03-2018 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.6E-47 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 Gene3D G3DSA:3.40.50.20 1 123 6.6E-55 T 28-03-2018 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 449 1.5E-231 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 SUPERFAMILY SSF51246 332 445 9.42E-48 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.4E-78 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 5.1E-45 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 Gene3D G3DSA:3.30.470.20 210 445 1.7E-99 T 28-03-2018 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 SUPERFAMILY SSF56059 83 349 3.89E-67 T 28-03-2018 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 Gene3D G3DSA:3.30.1490.20 124 209 6.8E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 SUPERFAMILY SSF52440 1 113 1.22E-51 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CPF12_RS01500 e75409be2af5e80f28e0cdc03b6f3f54 452 SMART SM00878 337 443 6.4E-71 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 Gene3D G3DSA:2.40.50.140 7 84 1.8E-29 T 28-03-2018 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 3.0E-29 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 SUPERFAMILY SSF50249 7 84 2.31E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.335 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 Pfam PF00366 Ribosomal protein S17 12 79 9.6E-30 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.4E-32 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 3.7E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 3.7E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06105 2ea0c01e0357c6de42af6ee56e61f7b8 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 3.7E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS05050 0fb96394095e8e6772dff66245f135c3 252 Gene3D G3DSA:3.40.50.300 1 232 8.4E-60 T 28-03-2018 CPF12_RS05050 0fb96394095e8e6772dff66245f135c3 252 Pfam PF00005 ABC transporter 17 164 2.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS05050 0fb96394095e8e6772dff66245f135c3 252 SUPERFAMILY SSF52540 2 226 4.05E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05050 0fb96394095e8e6772dff66245f135c3 252 SMART SM00382 26 213 4.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12255 293054277fa0de29b4895bc0b57e36e6 120 Gene3D G3DSA:1.10.10.10 3 103 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS12255 293054277fa0de29b4895bc0b57e36e6 120 Pfam PF03551 Transcriptional regulator PadR-like family 20 91 3.4E-20 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CPF12_RS12255 293054277fa0de29b4895bc0b57e36e6 120 SUPERFAMILY SSF46785 16 110 5.77E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08745 1bfe1b61e1463ed8ce185ce6849bcc48 387 Pfam PF07537 CamS sex pheromone cAM373 precursor 58 378 4.5E-113 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 CPF12_RS08745 1bfe1b61e1463ed8ce185ce6849bcc48 387 Gene3D G3DSA:3.10.570.10 37 386 3.8E-127 T 28-03-2018 CPF12_RS08745 1bfe1b61e1463ed8ce185ce6849bcc48 387 PIRSF PIRSF012509 1 386 2.2E-133 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 CPF12_RS05450 d18af8ac396daabec838c05595ea9cdf 108 SUPERFAMILY SSF47413 1 67 1.98E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05450 d18af8ac396daabec838c05595ea9cdf 108 Pfam PF01381 Helix-turn-helix 7 61 4.5E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05450 d18af8ac396daabec838c05595ea9cdf 108 SMART SM00530 6 61 6.7E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05450 d18af8ac396daabec838c05595ea9cdf 108 Gene3D G3DSA:1.10.260.40 1 94 8.1E-23 T 28-03-2018 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 Gene3D G3DSA:3.20.20.70 1 330 1.1E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 496 9.3E-205 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 SUPERFAMILY SSF110921 404 496 1.57E-16 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 Pfam PF00682 HMGL-like 3 272 9.0E-96 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 509 40.544 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 497 8.6E-32 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 SUPERFAMILY SSF51569 1 290 4.21E-93 T 28-03-2018 CPF12_RS01930 bfa60d10b0a955b92ebe8fcd329f4e5e 512 SMART SM00917 368 500 1.5E-26 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CPF12_RS06250 2985220ff57aa9527e7b1af144aec254 482 Gene3D G3DSA:3.30.1360.60 5 81 5.1E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS06250 2985220ff57aa9527e7b1af144aec254 482 SUPERFAMILY SSF55604 6 82 2.88E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS06250 2985220ff57aa9527e7b1af144aec254 482 Pfam PF02378 Phosphotransferase system, EIIC 133 414 6.1E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS06250 2985220ff57aa9527e7b1af144aec254 482 Pfam PF00367 phosphotransferase system, EIIB 9 41 1.5E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS06250 2985220ff57aa9527e7b1af144aec254 482 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS10530 9ff9cd84846c172caae19c47ee40bca4 130 Pfam PF13456 Reverse transcriptase-like 6 124 1.6E-18 T 28-03-2018 CPF12_RS10530 9ff9cd84846c172caae19c47ee40bca4 130 Gene3D G3DSA:3.30.420.10 1 130 6.6E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS10530 9ff9cd84846c172caae19c47ee40bca4 130 SUPERFAMILY SSF53098 1 122 5.69E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 Gene3D G3DSA:3.90.120.10 258 382 3.1E-20 T 28-03-2018 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 394 1.2E-75 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 Gene3D G3DSA:3.40.50.150 1 235 1.1E-49 T 28-03-2018 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 74 86 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 396 7.5E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 SUPERFAMILY SSF53335 247 395 1.41E-69 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 SUPERFAMILY SSF53335 2 198 1.41E-69 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 165 178 2.0E-14 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 2.0E-14 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CPF12_RS00595 12498850ebe12aaecfdaea5e12ce18f9 399 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 116 130 2.0E-14 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CPF12_RS01615 28692af12dd92c90fcb446e18eb40b2a 411 Gene3D G3DSA:3.20.20.70 8 175 1.3E-6 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS01615 28692af12dd92c90fcb446e18eb40b2a 411 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CPF12_RS01615 28692af12dd92c90fcb446e18eb40b2a 411 Pfam PF16325 Peptidase family U32 C-terminal domain 328 408 1.4E-24 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal CPF12_RS01615 28692af12dd92c90fcb446e18eb40b2a 411 Pfam PF01136 Peptidase family U32 84 313 6.1E-84 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CPF12_RS04595 a2d6983618afba8d67fc91830c170b19 502 Gene3D G3DSA:1.20.1570.10 278 339 2.3E-27 T 28-03-2018 CPF12_RS04595 a2d6983618afba8d67fc91830c170b19 502 Gene3D G3DSA:3.10.630.10 230 277 6.9E-14 T 28-03-2018 CPF12_RS04595 a2d6983618afba8d67fc91830c170b19 502 Gene3D G3DSA:3.10.630.10 3 229 1.2E-103 T 28-03-2018 CPF12_RS04595 a2d6983618afba8d67fc91830c170b19 502 PIRSF PIRSF033132 2 502 2.8E-241 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CPF12_RS04595 a2d6983618afba8d67fc91830c170b19 502 Pfam PF08903 Domain of unknown function (DUF1846) 4 500 1.3E-227 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CPF12_RS07770 0a633257c159e05891080ec6937fa676 370 Gene3D G3DSA:3.90.340.10 2 123 2.8E-39 T 28-03-2018 CPF12_RS07770 0a633257c159e05891080ec6937fa676 370 SUPERFAMILY SSF56512 5 361 3.66E-150 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CPF12_RS07770 0a633257c159e05891080ec6937fa676 370 PIRSF PIRSF037219 4 366 2.4E-163 T 28-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CPF12_RS07770 0a633257c159e05891080ec6937fa676 370 Gene3D G3DSA:3.90.1230.10 192 302 8.1E-49 T 28-03-2018 CPF12_RS07770 0a633257c159e05891080ec6937fa676 370 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 68 75 - T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CPF12_RS07770 0a633257c159e05891080ec6937fa676 370 Pfam PF02898 Nitric oxide synthase, oxygenase domain 7 360 2.8E-150 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CPF12_RS08455 9814ef060904982ae66ff4af2e529fff 154 Pfam PF04284 Protein of unknown function (DUF441) 7 146 1.2E-48 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CPF12_RS08455 9814ef060904982ae66ff4af2e529fff 154 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 7 131 6.0E-32 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CPF12_RS08455 9814ef060904982ae66ff4af2e529fff 154 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 18.739 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 73 86 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 SUPERFAMILY SSF51735 140 348 4.22E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 PIRSF PIRSF000188 1 353 6.8E-159 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 65 79 4.6E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 175 195 4.6E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 4.6E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 131 153 4.6E-19 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 Gene3D G3DSA:3.40.50.10860 1 144 1.5E-54 T 28-03-2018 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 SUPERFAMILY SSF53223 3 142 6.08E-49 T 28-03-2018 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 Gene3D G3DSA:3.40.50.720 145 364 2.4E-34 T 28-03-2018 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 SMART SM00839 143 351 6.5E-54 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 14 129 2.4E-29 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS01820 4740a4b0eefc0a4c249d8c217ad50695 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 223 316 1.1E-7 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 Gene3D G3DSA:2.30.38.10 330 416 2.4E-17 T 28-03-2018 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 Gene3D G3DSA:3.30.300.30 419 521 4.0E-27 T 28-03-2018 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 Gene3D G3DSA:3.40.50.980 12 179 1.8E-33 T 28-03-2018 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 SUPERFAMILY SSF56801 12 519 1.44E-135 T 28-03-2018 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 Pfam PF00501 AMP-binding enzyme 21 423 1.9E-74 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 Gene3D G3DSA:3.40.50.980 180 329 3.3E-34 T 28-03-2018 CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 3.4E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CPF12_RS05590 86b141c061c79cf4f7a7ec85258d99f3 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site CPF12_RS02680 963965894d9e361d54811db489049ca8 135 Gene3D G3DSA:3.40.30.10 1 131 2.7E-38 T 28-03-2018 CPF12_RS02680 963965894d9e361d54811db489049ca8 135 Pfam PF03960 ArsC family 5 113 7.6E-24 T 28-03-2018 IPR006660 Arsenate reductase-like CPF12_RS02680 963965894d9e361d54811db489049ca8 135 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 1.6E-37 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CPF12_RS02680 963965894d9e361d54811db489049ca8 135 SUPERFAMILY SSF52833 1 130 7.74E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS03945 1f97be967775104d984c864f5bc868df 168 PIRSF PIRSF019083 2 168 2.5E-49 T 28-03-2018 IPR016747 Phosphotransbutyrylase CPF12_RS03945 1f97be967775104d984c864f5bc868df 168 Pfam PF04892 VanZ like family 12 158 2.4E-17 T 28-03-2018 IPR006976 VanZ-like CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 SUPERFAMILY SSF46894 152 223 1.39E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 Gene3D G3DSA:1.10.10.10 128 226 3.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 SUPERFAMILY SSF52172 2 131 2.56E-14 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 SMART SM00448 3 116 1.4E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 214 2.9E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 Pfam PF00072 Response regulator receiver domain 5 116 9.9E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 SMART SM00421 160 217 8.1E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS06620 98a626202c08bff80b939faad7746f61 226 Gene3D G3DSA:3.40.50.2300 2 127 1.1E-14 T 28-03-2018 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 SMART SM00646 315 424 2.8E-28 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Gene3D G3DSA:2.40.50.110 166 238 2.1E-11 T 28-03-2018 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Gene3D G3DSA:2.40.50.110 28 96 1.9E-14 T 28-03-2018 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Gene3D G3DSA:2.40.50.110 97 165 1.2E-14 T 28-03-2018 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Pfam PF08239 Bacterial SH3 domain 185 235 1.1E-8 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Pfam PF08239 Bacterial SH3 domain 115 164 3.9E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Pfam PF08239 Bacterial SH3 domain 45 95 1.9E-12 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Gene3D G3DSA:3.40.630.40 251 429 1.2E-53 T 28-03-2018 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 PIRSF PIRSF037846 7 428 2.0E-133 T 28-03-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 SMART SM00287 106 166 1.5E-7 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 SMART SM00287 36 98 8.8E-15 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 SMART SM00287 176 238 2.0E-6 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 256 424 1.8E-49 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CPF12_RS01825 18dbe3b7920ad959b888b02cd9a13384 429 SUPERFAMILY SSF53187 255 427 1.29E-50 T 28-03-2018 CPF12_RS06565 96b246de79ec53c7c11be66181186113 316 Gene3D G3DSA:3.90.25.10 171 312 1.9E-37 T 28-03-2018 CPF12_RS06565 96b246de79ec53c7c11be66181186113 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 244 4.9E-62 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CPF12_RS06565 96b246de79ec53c7c11be66181186113 316 SUPERFAMILY SSF51735 3 312 1.01E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS06565 96b246de79ec53c7c11be66181186113 316 Gene3D G3DSA:3.40.50.720 2 170 5.1E-32 T 28-03-2018 CPF12_RS02375 084231c10d204c3c53123de671194c4d 113 Gene3D G3DSA:1.10.10.10 15 112 2.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02375 084231c10d204c3c53123de671194c4d 113 SUPERFAMILY SSF46785 6 109 1.72E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02375 084231c10d204c3c53123de671194c4d 113 Pfam PF01638 HxlR-like helix-turn-helix 17 106 5.4E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CPF12_RS04270 b8518ed9ff52a5f6d60a0d1b306305cf 219 Pfam PF01610 Transposase 1 213 5.1E-36 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS01090 85b956c26f312d5afdd181536be75867 228 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 6 212 16.68 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CPF12_RS01090 85b956c26f312d5afdd181536be75867 228 Gene3D G3DSA:2.160.20.70 97 215 5.1E-26 T 28-03-2018 CPF12_RS01090 85b956c26f312d5afdd181536be75867 228 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 109 208 3.9E-18 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CPF12_RS01090 85b956c26f312d5afdd181536be75867 228 SUPERFAMILY SSF63848 107 211 1.07E-18 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CPF12_RS01090 85b956c26f312d5afdd181536be75867 228 Gene3D G3DSA:3.30.750.50 7 96 5.9E-21 T 28-03-2018 CPF12_RS09855 874d032cf44f2f20f07eba6ffc3086ad 206 SUPERFAMILY SSF50249 94 203 2.94E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS09855 874d032cf44f2f20f07eba6ffc3086ad 206 Pfam PF14794 Domain of unknown function (DUF4479) 24 88 5.5E-13 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CPF12_RS09855 874d032cf44f2f20f07eba6ffc3086ad 206 Gene3D G3DSA:3.30.1940.10 25 92 3.6E-16 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CPF12_RS09855 874d032cf44f2f20f07eba6ffc3086ad 206 Gene3D G3DSA:2.40.50.140 93 206 6.1E-35 T 28-03-2018 CPF12_RS09855 874d032cf44f2f20f07eba6ffc3086ad 206 Pfam PF01588 Putative tRNA binding domain 98 192 9.7E-22 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 5.3E-100 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 PIRSF PIRSF001359 1 284 1.0E-109 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 Gene3D G3DSA:3.20.20.70 1 284 8.0E-94 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 283 6.5E-90 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 SUPERFAMILY SSF51569 1 284 1.23E-90 T 28-03-2018 CPF12_RS11010 a11d1f1c8add36cde514805c33b697b9 284 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 284 1.5E-110 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 SUPERFAMILY SSF144052 4 409 2.88E-136 T 28-03-2018 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 Gene3D G3DSA:3.40.1830.10 5 175 8.9E-55 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 6.6E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS08355 3617267e56d1cc1ff132d2b6f8b0ee66 410 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 3.6E-158 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS09445 52d5b45f79a6b9835316eb55159b3b6d 125 SMART SM00871 1 124 0.0043 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CPF12_RS09445 52d5b45f79a6b9835316eb55159b3b6d 125 Gene3D G3DSA:3.20.80.10 1 124 4.5E-17 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CPF12_RS09445 52d5b45f79a6b9835316eb55159b3b6d 125 Pfam PF14526 Integron-associated effector binding protein 12 123 2.6E-8 T 28-03-2018 IPR029441 Integron-associated effector binding protein CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 357 59.795 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 355 1.3E-102 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 Pfam PF00155 Aminotransferase class I and II 31 351 6.8E-52 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 SUPERFAMILY SSF53383 16 357 2.25E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 Gene3D G3DSA:3.90.1150.10 281 358 4.4E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS00070 e67de3c7d880f3b51b24f69841d12e55 359 Gene3D G3DSA:3.40.640.10 42 280 2.7E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS03190 c143241563b91c5994d4a6777b9386f3 211 Pfam PF13460 NAD(P)H-binding 7 186 4.2E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03190 c143241563b91c5994d4a6777b9386f3 211 SUPERFAMILY SSF51735 1 200 5.69E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03190 c143241563b91c5994d4a6777b9386f3 211 Gene3D G3DSA:3.40.50.720 1 211 7.8E-24 T 28-03-2018 CPF12_RS02355 171f4b9da4aef11d641f29d1dd779d03 175 Pfam PF02674 Colicin V production protein 3 158 3.0E-27 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CPF12_RS03845 4a9e57bce3943b04dad5e614e3410643 293 SUPERFAMILY SSF53850 41 270 4.94E-46 T 28-03-2018 CPF12_RS03845 4a9e57bce3943b04dad5e614e3410643 293 Pfam PF03180 NLPA lipoprotein 36 267 3.9E-46 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS03845 4a9e57bce3943b04dad5e614e3410643 293 Gene3D G3DSA:3.40.190.10 27 125 1.1E-7 T 28-03-2018 CPF12_RS03845 4a9e57bce3943b04dad5e614e3410643 293 Gene3D G3DSA:3.40.190.10 126 269 1.0E-26 T 28-03-2018 CPF12_RS12045 9dd0f47d070557466d33d2f0d40d32e6 120 Pfam PF11337 Protein of unknown function (DUF3139) 1 75 1.2E-8 T 28-03-2018 IPR021486 Protein of unknown function DUF3139 CPF12_RS02220 768c8b8194bcb674dd2f9580da924fb6 395 SUPERFAMILY SSF55931 9 393 1.18E-80 T 28-03-2018 CPF12_RS02220 768c8b8194bcb674dd2f9580da924fb6 395 Pfam PF04262 Glutamate-cysteine ligase 234 308 1.9E-6 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CPF12_RS02220 768c8b8194bcb674dd2f9580da924fb6 395 Pfam PF04262 Glutamate-cysteine ligase 10 194 2.5E-48 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 SUPERFAMILY SSF143437 3 174 1.5E-53 T 28-03-2018 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 SMART SM00981 74 166 9.1E-26 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 Pfam PF02926 THUMP domain 38 165 1.5E-25 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 Gene3D G3DSA:3.40.50.620 176 404 9.0E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 372 8.4E-64 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 Gene3D G3DSA:3.30.2300.10 81 164 1.2E-20 T 28-03-2018 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 159.037 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 Gene3D G3DSA:3.30.70.1510 5 80 4.0E-23 T 28-03-2018 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 374 1.9E-126 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CPF12_RS08935 ad04a9c191f4f137f766ae3c6428a794 404 SUPERFAMILY SSF52402 176 388 1.21E-50 T 28-03-2018 CPF12_RS10660 d100d61f8d971e46452b12d7087d6312 191 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 8 187 1.4E-51 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CPF12_RS10660 d100d61f8d971e46452b12d7087d6312 191 Pfam PF02669 K+-transporting ATPase, c chain 9 186 1.1E-58 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CPF12_RS10660 d100d61f8d971e46452b12d7087d6312 191 PIRSF PIRSF001296 4 191 1.4E-59 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CPF12_RS10660 d100d61f8d971e46452b12d7087d6312 191 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 187 28.65 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CPF12_RS05940 257c1b29d76f4df59d709400444f567f 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4 158 4.8E-63 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CPF12_RS05940 257c1b29d76f4df59d709400444f567f 158 SUPERFAMILY SSF69765 2 157 2.09E-61 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CPF12_RS05940 257c1b29d76f4df59d709400444f567f 158 Gene3D G3DSA:3.30.1330.50 1 158 4.2E-67 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CPF12_RS05940 257c1b29d76f4df59d709400444f567f 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 37 52 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CPF12_RS05940 257c1b29d76f4df59d709400444f567f 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 3 158 34.287 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CPF12_RS05940 257c1b29d76f4df59d709400444f567f 158 Pfam PF02542 YgbB family 3 157 8.2E-61 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 SMART SM00382 319 483 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 SMART SM00382 29 186 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 Gene3D G3DSA:3.40.50.300 253 517 9.3E-43 T 28-03-2018 CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 Gene3D G3DSA:3.40.50.300 1 216 2.9E-40 T 28-03-2018 CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 Pfam PF00005 ABC transporter 311 438 3.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 Pfam PF00005 ABC transporter 25 135 5.7E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 SUPERFAMILY SSF52540 276 484 6.69E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS12235 d54c3641dda53c3454d9dc22f35b50f7 543 SUPERFAMILY SSF52540 4 206 2.25E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 170 230 6.0E-14 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 SUPERFAMILY SSF81301 7 137 6.76E-40 T 28-03-2018 CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 250 388 2.9E-33 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 Pfam PF01743 Poly A polymerase head domain 23 142 5.2E-34 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 Gene3D G3DSA:1.10.3090.10 143 391 3.6E-39 T 28-03-2018 CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 Hamap MF_01263 CCA-adding enzyme [cca]. 3 392 39.439 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 Gene3D G3DSA:3.30.460.10 6 142 1.3E-42 T 28-03-2018 CPF12_RS10290 31cad32b52f8704672758e87e8254c41 392 SUPERFAMILY SSF81891 141 390 1.1E-47 T 28-03-2018 CPF12_RS01165 a007356b59b3353fc937428e240aad5e 87 Pfam PF01541 GIY-YIG catalytic domain 3 82 6.7E-5 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS01165 a007356b59b3353fc937428e240aad5e 87 Gene3D G3DSA:3.40.1440.10 2 87 4.1E-6 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS01400 323ac3c50daaca4463983edc0b9e7f8b 202 Pfam PF01725 Ham1 family 4 191 5.3E-56 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CPF12_RS01400 323ac3c50daaca4463983edc0b9e7f8b 202 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 193 3.5E-60 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CPF12_RS01400 323ac3c50daaca4463983edc0b9e7f8b 202 Gene3D G3DSA:3.90.950.10 1 196 1.5E-73 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CPF12_RS01400 323ac3c50daaca4463983edc0b9e7f8b 202 SUPERFAMILY SSF52972 1 193 5.23E-67 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CPF12_RS01400 323ac3c50daaca4463983edc0b9e7f8b 202 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 195 47.124 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 556 46.229 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 SUPERFAMILY SSF52016 376 556 8.63E-61 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 121 131 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 SUPERFAMILY SSF143975 2 375 1.44E-134 T 28-03-2018 CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 464 475 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 556 1.8E-239 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CPF12_RS01950 a52b297e21b337a18e8fb44af3daf27c 562 Pfam PF00920 Dehydratase family 33 552 7.6E-222 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CPF12_RS12095 77b07a9cff8718253436cf7f8772986a 261 SUPERFAMILY SSF53850 2 259 1.22E-67 T 28-03-2018 CPF12_RS12095 77b07a9cff8718253436cf7f8772986a 261 SMART SM00079 37 259 6.9E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CPF12_RS12095 77b07a9cff8718253436cf7f8772986a 261 Gene3D G3DSA:3.40.190.10 28 142 4.4E-30 T 28-03-2018 CPF12_RS12095 77b07a9cff8718253436cf7f8772986a 261 SMART SM00062 37 260 5.1E-71 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS12095 77b07a9cff8718253436cf7f8772986a 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 257 5.8E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS12095 77b07a9cff8718253436cf7f8772986a 261 Gene3D G3DSA:3.40.190.10 143 219 1.7E-16 T 28-03-2018 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 Gene3D G3DSA:3.40.50.300 148 353 3.4E-64 T 28-03-2018 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 340 3.0E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 621 38.13 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 Gene3D G3DSA:1.10.8.60 354 430 3.1E-23 T 28-03-2018 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 Pfam PF01434 Peptidase family M41 402 610 1.4E-83 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 Pfam PF06480 FtsH Extracellular 9 93 1.0E-7 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 SMART SM00382 204 343 4.3E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 SUPERFAMILY SSF52540 166 412 6.98E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 SUPERFAMILY SSF140990 422 618 1.44E-70 T 28-03-2018 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 118 611 7.9E-243 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CPF12_RS05815 221bda0ec9887bd1beb79acba4441347 676 ProSitePatterns PS00674 AAA-protein family signature. 311 329 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CPF12_RS02640 a1f9de61f2798a5a3aa8d2ce655db4fe 599 Gene3D G3DSA:3.40.50.1110 404 595 4.8E-15 T 28-03-2018 CPF12_RS02640 a1f9de61f2798a5a3aa8d2ce655db4fe 599 Pfam PF01757 Acyltransferase family 11 342 3.9E-21 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CPF12_RS02640 a1f9de61f2798a5a3aa8d2ce655db4fe 599 SUPERFAMILY SSF52266 433 592 9.49E-15 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CPF12_RS00180 e8aeb93391ab8028a909045addff1fe3 89 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 21 40 - T 28-03-2018 IPR020808 Bacterial microcompartments protein, conserved site CPF12_RS00180 e8aeb93391ab8028a909045addff1fe3 89 Pfam PF00936 BMC domain 4 79 5.4E-29 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS00180 e8aeb93391ab8028a909045addff1fe3 89 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 47 8.0E-16 T 28-03-2018 CPF12_RS00180 e8aeb93391ab8028a909045addff1fe3 89 SUPERFAMILY SSF143414 3 88 9.29E-32 T 28-03-2018 CPF12_RS00180 e8aeb93391ab8028a909045addff1fe3 89 SMART SM00877 3 79 5.2E-37 T 28-03-2018 IPR000249 Microcompartment protein, bacteria CPF12_RS05605 8465fc6dd66a6a9cf713ead7f3bf5e51 472 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 448 3.2E-168 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CPF12_RS05605 8465fc6dd66a6a9cf713ead7f3bf5e51 472 PIRSF PIRSF006446 1 472 8.9E-178 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CPF12_RS06585 5434915065d5bd0eee581994457266c9 267 Gene3D G3DSA:3.90.550.10 28 267 1.1E-11 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS06585 5434915065d5bd0eee581994457266c9 267 SUPERFAMILY SSF53448 49 246 1.03E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS06585 5434915065d5bd0eee581994457266c9 267 Pfam PF00535 Glycosyl transferase family 2 55 124 4.4E-6 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CPF12_RS09440 de932d2de9cdaddd0bc5073af5f4e1f5 299 Gene3D G3DSA:1.10.10.10 1 63 1.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09440 de932d2de9cdaddd0bc5073af5f4e1f5 299 SMART SM00420 5 61 0.0018 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS09440 de932d2de9cdaddd0bc5073af5f4e1f5 299 SUPERFAMILY SSF46785 2 52 5.88E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09440 de932d2de9cdaddd0bc5073af5f4e1f5 299 Pfam PF13280 WYL domain 137 296 6.8E-25 T 28-03-2018 IPR026881 WYL domain CPF12_RS09440 de932d2de9cdaddd0bc5073af5f4e1f5 299 PIRSF PIRSF016838 1 297 1.6E-26 T 28-03-2018 IPR028349 Protein PafC CPF12_RS09440 de932d2de9cdaddd0bc5073af5f4e1f5 299 Pfam PF08279 HTH domain 5 54 4.7E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS07570 ee97526d3835c644ab949a837725eaf8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.2E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CPF12_RS07570 ee97526d3835c644ab949a837725eaf8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 1.2E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CPF12_RS07570 ee97526d3835c644ab949a837725eaf8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.2E-9 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CPF12_RS07570 ee97526d3835c644ab949a837725eaf8 77 Pfam PF03840 Preprotein translocase SecG subunit 4 74 2.5E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CPF12_RS07570 ee97526d3835c644ab949a837725eaf8 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 3.0E-21 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CPF12_RS03440 1ef704adfe67c2c85d472d85f05e1d68 184 Pfam PF04238 Protein of unknown function (DUF420) 50 180 3.2E-39 T 28-03-2018 IPR007352 Protein of unknown function DUF420 CPF12_RS03440 1ef704adfe67c2c85d472d85f05e1d68 184 Gene3D G3DSA:1.20.120.80 5 183 1.5E-5 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS00565 5327aae22a342a36964381924159fa8e 407 Pfam PF13791 Sigma factor regulator C-terminal 227 398 4.7E-19 T 28-03-2018 IPR025672 Sigma factor regulator C-terminal domain CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 Gene3D G3DSA:3.40.140.20 214 359 6.0E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 Gene3D G3DSA:3.40.140.20 361 502 7.1E-46 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 PIRSF PIRSF000414 1 512 2.1E-205 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 512 43.635 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 SUPERFAMILY SSF53927 206 512 4.11E-121 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 512 1.6E-218 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 SMART SM00851 13 128 9.9E-53 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 Pfam PF02142 MGS-like domain 13 127 3.3E-27 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 445 1.7E-115 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 SUPERFAMILY SSF52335 2 193 3.14E-68 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 SMART SM00798 133 447 1.2E-183 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CPF12_RS08720 750c0755a1c94353bb6022a2db90d38e 512 Gene3D G3DSA:3.40.50.1380 1 191 1.3E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 SMART SM00357 3 66 3.3E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 SUPERFAMILY SSF50249 1 64 6.43E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 PRINTS PR00050 Cold shock protein signature 39 57 4.7E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 PRINTS PR00050 Cold shock protein signature 24 33 4.7E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 PRINTS PR00050 Cold shock protein signature 4 19 4.7E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.5E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 Gene3D G3DSA:2.40.50.140 1 65 1.9E-28 T 28-03-2018 CPF12_RS08315 f35770679ed06ef19abbacbc419172d3 66 PIRSF PIRSF002599 1 66 9.4E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CPF12_RS04315 d61ae9f2f6b204ecdc314c30ab670e6a 262 Gene3D G3DSA:1.10.3720.10 8 262 4.7E-29 T 28-03-2018 CPF12_RS04315 d61ae9f2f6b204ecdc314c30ab670e6a 262 SUPERFAMILY SSF161098 8 261 9.35E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06225 68a747353851200e953f25d2de7245f5 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CPF12_RS06225 68a747353851200e953f25d2de7245f5 130 SUPERFAMILY SSF54211 5 130 1.78E-50 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS06225 68a747353851200e953f25d2de7245f5 130 Gene3D G3DSA:3.30.230.10 3 130 7.8E-54 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS06225 68a747353851200e953f25d2de7245f5 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.524 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CPF12_RS06225 68a747353851200e953f25d2de7245f5 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.6E-47 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CPF12_RS09720 49cee2467319eb483d74b2b0f684445f 172 SUPERFAMILY SSF48150 10 170 7.69E-52 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CPF12_RS09720 49cee2467319eb483d74b2b0f684445f 172 Gene3D G3DSA:1.10.340.30 5 171 7.3E-53 T 28-03-2018 CPF12_RS09720 49cee2467319eb483d74b2b0f684445f 172 Pfam PF03352 Methyladenine glycosylase 10 167 4.3E-52 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CPF12_RS11290 90b4376e689001579b20d6fc8a13db4b 210 Pfam PF13460 NAD(P)H-binding 7 196 5.9E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS11290 90b4376e689001579b20d6fc8a13db4b 210 Gene3D G3DSA:3.40.50.720 1 207 6.6E-12 T 28-03-2018 CPF12_RS11290 90b4376e689001579b20d6fc8a13db4b 210 SUPERFAMILY SSF51735 1 208 6.6E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03390 75322974f7fd6d897325f5422b1f87c9 149 SUPERFAMILY SSF52833 35 129 1.87E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS03390 75322974f7fd6d897325f5422b1f87c9 149 Pfam PF00085 Thioredoxin 41 144 2.0E-9 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CPF12_RS03390 75322974f7fd6d897325f5422b1f87c9 149 Gene3D G3DSA:3.40.30.10 26 148 1.7E-18 T 28-03-2018 CPF12_RS00495 2ad1d2214998450ffe2b308189a81e09 282 Gene3D G3DSA:3.40.50.1110 1 245 8.2E-50 T 28-03-2018 CPF12_RS00495 2ad1d2214998450ffe2b308189a81e09 282 SUPERFAMILY SSF52266 2 270 1.22E-75 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CPF12_RS00495 2ad1d2214998450ffe2b308189a81e09 282 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 2 224 4.0E-53 T 28-03-2018 IPR005181 Sialate O-acetylesterase domain CPF12_RS00615 a01e26a3e9e9f21ba4ddc5c4fe96bec8 481 Gene3D G3DSA:1.10.10.10 2 68 5.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00615 a01e26a3e9e9f21ba4ddc5c4fe96bec8 481 Pfam PF05043 Mga helix-turn-helix domain 73 155 3.3E-9 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS00615 a01e26a3e9e9f21ba4ddc5c4fe96bec8 481 Pfam PF08279 HTH domain 14 64 3.8E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CPF12_RS00615 a01e26a3e9e9f21ba4ddc5c4fe96bec8 481 Gene3D G3DSA:1.10.10.10 81 143 0.011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07450 ae97f55960c87ae1463c8bec794edb2e 449 Pfam PF07690 Major Facilitator Superfamily 2 390 7.3E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS07450 ae97f55960c87ae1463c8bec794edb2e 449 Gene3D G3DSA:1.20.1250.20 1 179 7.8E-31 T 28-03-2018 CPF12_RS07450 ae97f55960c87ae1463c8bec794edb2e 449 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 3 400 9.6E-89 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS07450 ae97f55960c87ae1463c8bec794edb2e 449 Gene3D G3DSA:1.20.1250.20 238 445 3.6E-21 T 28-03-2018 CPF12_RS07450 ae97f55960c87ae1463c8bec794edb2e 449 SUPERFAMILY SSF103473 229 444 4.32E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS07450 ae97f55960c87ae1463c8bec794edb2e 449 SUPERFAMILY SSF103473 2 178 4.32E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS08415 3cb2c5a713462a7060d89d5d32328930 309 Pfam PF02272 DHHA1 domain 179 307 4.4E-12 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CPF12_RS08415 3cb2c5a713462a7060d89d5d32328930 309 SUPERFAMILY SSF64182 12 300 2.88E-70 T 28-03-2018 CPF12_RS08415 3cb2c5a713462a7060d89d5d32328930 309 Gene3D G3DSA:3.90.1640.10 1 196 2.4E-42 T 28-03-2018 CPF12_RS08415 3cb2c5a713462a7060d89d5d32328930 309 Pfam PF01368 DHH family 15 152 2.0E-12 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CPF12_RS09580 c4326426014373d8d8c19f08462d86f7 309 Pfam PF00005 ABC transporter 25 159 4.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS09580 c4326426014373d8d8c19f08462d86f7 309 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS09580 c4326426014373d8d8c19f08462d86f7 309 Gene3D G3DSA:3.40.50.300 1 238 7.6E-64 T 28-03-2018 CPF12_RS09580 c4326426014373d8d8c19f08462d86f7 309 SMART SM00382 30 223 2.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS09580 c4326426014373d8d8c19f08462d86f7 309 SUPERFAMILY SSF52540 5 222 2.92E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02445 ef40ddb764af7b211e9d25c0ca668021 1141 SUPERFAMILY SSF53756 841 1100 7.53E-6 T 28-03-2018 CPF12_RS02445 ef40ddb764af7b211e9d25c0ca668021 1141 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 791 1132 2.5E-39 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CPF12_RS02445 ef40ddb764af7b211e9d25c0ca668021 1141 Gene3D G3DSA:3.40.50.2000 935 1072 7.7E-5 T 28-03-2018 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 PIRSF PIRSF000447 1 412 2.7E-177 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 Gene3D G3DSA:3.40.47.10 261 412 2.0E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 Gene3D G3DSA:3.40.47.10 1 257 1.1E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 SUPERFAMILY SSF53901 3 250 1.28E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 3.0E-54 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 SUPERFAMILY SSF53901 214 410 2.1E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 1.8E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 3.4E-190 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CPF12_RS02720 720af6e7fdac8588690fcb09f311b008 412 SMART SM00825 Beta-ketoacyl synthase 5 412 1.5E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CPF12_RS08910 274ae4081e80d37e256a150637e21ed3 241 SUPERFAMILY SSF89550 1 199 9.02E-12 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CPF12_RS08910 274ae4081e80d37e256a150637e21ed3 241 PIRSF PIRSF016557 1 240 1.9E-78 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CPF12_RS08910 274ae4081e80d37e256a150637e21ed3 241 Gene3D G3DSA:3.20.20.140 1 240 2.3E-19 T 28-03-2018 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 Gene3D G3DSA:3.30.950.10 123 235 1.0E-41 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 232 36.573 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 SUPERFAMILY SSF53790 13 230 2.22E-83 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 PIRSF PIRSF005917 2 292 1.0E-101 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 287 8.5E-81 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 92 103 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 Gene3D G3DSA:3.40.1010.10 12 122 2.6E-42 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CPF12_RS05700 a0c65322b40aaf9f339150b17309260c 299 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 213 2.4E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CPF12_RS02180 a772afff103d34eb15d5e78c60101829 197 Pfam PF00005 ABC transporter 20 151 7.8E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02180 a772afff103d34eb15d5e78c60101829 197 Gene3D G3DSA:3.40.50.300 1 197 4.5E-28 T 28-03-2018 CPF12_RS02180 a772afff103d34eb15d5e78c60101829 197 SUPERFAMILY SSF52540 8 196 2.5E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01030 cea06a4d1db9bc57dc8847867d5c6611 127 Gene3D G3DSA:3.30.300.20 7 126 2.6E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS01030 cea06a4d1db9bc57dc8847867d5c6611 127 Pfam PF02566 OsmC-like protein 25 119 9.1E-17 T 28-03-2018 IPR003718 OsmC/Ohr family CPF12_RS01030 cea06a4d1db9bc57dc8847867d5c6611 127 SUPERFAMILY SSF82784 9 121 4.97E-17 T 28-03-2018 IPR003718 OsmC/Ohr family CPF12_RS05730 19b97481d6be404d051aa02727a6ded0 84 Gene3D G3DSA:2.30.30.100 2 76 7.8E-33 T 28-03-2018 CPF12_RS05730 19b97481d6be404d051aa02727a6ded0 84 Pfam PF06257 Biofilm formation stimulator VEG 4 74 2.4E-31 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CPF12_RS05730 19b97481d6be404d051aa02727a6ded0 84 PIRSF PIRSF037257 1 84 1.3E-36 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 Gene3D G3DSA:1.50.10.10 368 619 1.3E-24 T 28-03-2018 CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 SUPERFAMILY SSF52833 6 131 3.02E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 SUPERFAMILY SSF48208 182 532 2.46E-53 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 Gene3D G3DSA:1.50.10.10 218 367 5.3E-19 T 28-03-2018 CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 PIRSF PIRSF006402 1 617 1.5E-186 T 28-03-2018 IPR024705 Spermatogenesis-associated protein 20 CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 Pfam PF03190 Protein of unknown function, DUF255 6 167 2.4E-69 T 28-03-2018 IPR004879 Domain of unknown function DUF255 CPF12_RS09180 98500cf53faabb0bac53067459de2ca0 658 Gene3D G3DSA:3.40.30.10 4 175 7.8E-28 T 28-03-2018 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 SMART SM00382 489 668 5.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 Pfam PF00005 ABC transporter 481 619 1.4E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 Gene3D G3DSA:3.40.50.300 451 694 2.9E-46 T 28-03-2018 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 Gene3D G3DSA:3.90.70.10 6 123 5.2E-24 T 28-03-2018 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 Gene3D G3DSA:1.20.1560.10 124 450 2.1E-21 T 28-03-2018 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 Pfam PF03412 Peptidase C39 family 2 134 1.0E-36 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 ProSitePatterns PS00211 ABC transporters family signature. 592 606 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 SUPERFAMILY SSF52540 460 688 5.93E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 Pfam PF00664 ABC transporter transmembrane region 160 421 1.5E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS11675 df5bd213a4850865f6ec18951a2f1e65 694 SUPERFAMILY SSF90123 163 446 6.41E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 2.2E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 SMART SM00420 6 58 5.7E-20 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 Pfam PF00455 DeoR C terminal sensor domain 75 228 6.7E-46 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 SUPERFAMILY SSF100950 75 228 2.46E-32 T 28-03-2018 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 SUPERFAMILY SSF46785 4 61 1.25E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 Gene3D G3DSA:3.40.50.1360 66 244 1.9E-36 T 28-03-2018 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 SMART SM01134 73 231 3.2E-61 T 28-03-2018 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS07980 2737fd738d6c1c55a5a1d40e7fc43d2a 248 Gene3D G3DSA:1.10.10.10 1 65 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03580 2e2d7a79a72d611393c8c8a2388be773 392 Gene3D G3DSA:2.30.130.10 2 63 1.6E-11 T 28-03-2018 IPR002478 PUA domain GO:0003723 CPF12_RS03580 2e2d7a79a72d611393c8c8a2388be773 392 Gene3D G3DSA:3.30.750.80 68 163 7.7E-22 T 28-03-2018 CPF12_RS03580 2e2d7a79a72d611393c8c8a2388be773 392 Gene3D G3DSA:3.40.50.150 164 392 3.8E-27 T 28-03-2018 CPF12_RS03580 2e2d7a79a72d611393c8c8a2388be773 392 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 107 375 2.9E-28 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CPF12_RS03580 2e2d7a79a72d611393c8c8a2388be773 392 SUPERFAMILY SSF88697 4 67 5.47E-13 T 28-03-2018 IPR015947 PUA-like domain CPF12_RS03580 2e2d7a79a72d611393c8c8a2388be773 392 SUPERFAMILY SSF53335 78 388 2.82E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS07925 08140639ebe65cc7bfcdc8819ba70418 285 Gene3D G3DSA:3.20.20.410 2 281 5.9E-69 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CPF12_RS07925 08140639ebe65cc7bfcdc8819ba70418 285 Pfam PF01904 Protein of unknown function DUF72 20 264 1.7E-53 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CPF12_RS07925 08140639ebe65cc7bfcdc8819ba70418 285 SUPERFAMILY SSF117396 1 265 4.58E-64 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 Gene3D G3DSA:1.25.40.80 129 284 1.0E-30 T 28-03-2018 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 Pfam PF03441 FAD binding domain of DNA photolyase 267 454 1.8E-76 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 SUPERFAMILY SSF52425 3 163 3.4E-30 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 Gene3D G3DSA:1.10.579.10 285 459 9.0E-68 T 28-03-2018 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 Pfam PF00875 DNA photolyase 4 156 2.4E-26 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 336 355 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 SUPERFAMILY SSF48173 201 456 2.09E-98 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 PRINTS PR00147 DNA photolyase signature 336 354 2.7E-29 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 PRINTS PR00147 DNA photolyase signature 375 389 2.7E-29 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 PRINTS PR00147 DNA photolyase signature 139 155 2.7E-29 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 PRINTS PR00147 DNA photolyase signature 316 332 2.7E-29 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CPF12_RS02495 07bea8ace6678a042bb790c0f40b5749 460 Gene3D G3DSA:3.40.50.620 1 126 2.2E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 PIRSF PIRSF001586 1 223 3.4E-90 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 205 8.9E-44 T 28-03-2018 CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 Gene3D G3DSA:3.40.50.880 1 222 2.9E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 SMART SM01211 1 220 1.2E-132 T 28-03-2018 CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 45.391 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 SUPERFAMILY SSF52317 2 220 3.2E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS08695 bf50cc3e8f953203115ec37eb62ca565 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 2.6E-96 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CPF12_RS12385 382579f45a00d22914e4c7a347a4ed91 201 Pfam PF01553 Acyltransferase 21 142 2.3E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CPF12_RS12385 382579f45a00d22914e4c7a347a4ed91 201 SUPERFAMILY SSF69593 2 174 1.28E-38 T 28-03-2018 CPF12_RS12385 382579f45a00d22914e4c7a347a4ed91 201 Gene3D G3DSA:3.40.1130.10 1 200 4.4E-37 T 28-03-2018 CPF12_RS12385 382579f45a00d22914e4c7a347a4ed91 201 SMART SM00563 34 145 2.3E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 717 5.3E-220 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Hamap MF_00953 DNA topoisomerase 3 [topB]. 2 627 57.352 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Gene3D G3DSA:3.40.50.140 2 154 3.9E-39 T 28-03-2018 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 501 515 6.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 386 402 6.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 6.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 6.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 304 313 6.9E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Pfam PF01751 Toprim domain 4 134 8.5E-15 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS02400 4738ec79f2400925c430239e40605401 721 SMART SM00436 126 216 6.2E-35 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Gene3D G3DSA:1.10.460.10 455 589 4.7E-20 T 28-03-2018 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 SUPERFAMILY SSF56712 2 587 1.96E-161 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Gene3D G3DSA:3.30.65.10 634 664 0.058 T 28-03-2018 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Gene3D G3DSA:3.30.65.10 590 633 8.1E-8 T 28-03-2018 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 298 313 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Pfam PF01131 DNA topoisomerase 153 573 4.2E-107 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Gene3D G3DSA:1.10.460.10 155 354 7.8E-40 T 28-03-2018 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 SMART SM00437 261 538 6.6E-65 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 Gene3D G3DSA:2.70.20.10 355 454 6.1E-19 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CPF12_RS02400 4738ec79f2400925c430239e40605401 721 SMART SM00493 2 125 2.0E-13 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS01520 0314c5b957c9f691f0c10092405db4ae 122 Gene3D G3DSA:3.40.250.10 23 121 4.6E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS01520 0314c5b957c9f691f0c10092405db4ae 122 Pfam PF00581 Rhodanese-like domain 31 117 3.3E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS01520 0314c5b957c9f691f0c10092405db4ae 122 SMART SM00450 26 121 2.2E-23 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS01520 0314c5b957c9f691f0c10092405db4ae 122 SUPERFAMILY SSF52821 6 117 2.49E-30 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS04655 7d9269fe3086504a5e16b2563f2bd9fd 178 Pfam PF01872 RibD C-terminal domain 3 168 3.4E-20 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CPF12_RS04655 7d9269fe3086504a5e16b2563f2bd9fd 178 Gene3D G3DSA:3.40.430.10 1 178 1.6E-37 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CPF12_RS04655 7d9269fe3086504a5e16b2563f2bd9fd 178 SUPERFAMILY SSF53597 3 169 3.67E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CPF12_RS04300 6b3eb0c2a74d82048a174152c028be76 311 SUPERFAMILY SSF53474 66 199 3.85E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS04300 6b3eb0c2a74d82048a174152c028be76 311 SUPERFAMILY SSF53474 238 310 3.85E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS04300 6b3eb0c2a74d82048a174152c028be76 311 Pfam PF12146 Serine aminopeptidase, S33 88 191 4.0E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CPF12_RS04300 6b3eb0c2a74d82048a174152c028be76 311 Gene3D G3DSA:3.40.50.1820 46 311 4.0E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS07365 c14ea1308bbab627194f4f6ccc55cfbe 226 Pfam PF13731 WxL domain surface cell wall-binding 31 219 8.4E-32 T 28-03-2018 IPR027994 WxL domain CPF12_RS07365 c14ea1308bbab627194f4f6ccc55cfbe 226 Gene3D G3DSA:2.60.40.1740 121 225 0.0016 T 28-03-2018 CPF12_RS10920 fa638047b6dcf32d7a0f35c0ede87c4f 296 Gene3D G3DSA:1.10.3720.10 20 288 8.7E-44 T 28-03-2018 CPF12_RS10920 fa638047b6dcf32d7a0f35c0ede87c4f 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 294 2.4E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS10920 fa638047b6dcf32d7a0f35c0ede87c4f 296 SUPERFAMILY SSF161098 93 281 6.41E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06705 465df04483241b7b367099df2d0837e7 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 292 1.7E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06705 465df04483241b7b367099df2d0837e7 294 SUPERFAMILY SSF161098 7 279 1.7E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06705 465df04483241b7b367099df2d0837e7 294 Gene3D G3DSA:1.10.3720.10 1 281 3.1E-37 T 28-03-2018 CPF12_RS06705 465df04483241b7b367099df2d0837e7 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 285 2.2E-79 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PRINTS PR00069 Aldo-keto reductase signature 164 193 4.6E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PRINTS PR00069 Aldo-keto reductase signature 130 147 4.6E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PRINTS PR00069 Aldo-keto reductase signature 40 64 4.6E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PRINTS PR00069 Aldo-keto reductase signature 201 225 4.6E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PRINTS PR00069 Aldo-keto reductase signature 100 118 4.6E-49 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PIRSF PIRSF000097 2 124 2.3E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 PIRSF PIRSF000097 119 278 5.3E-47 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 Pfam PF00248 Aldo/keto reductase family 28 264 1.9E-43 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS03000 003f624229b04776a3c780c315be186a 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS03000 003f624229b04776a3c780c315be186a 281 Gene3D G3DSA:3.20.20.100 2 280 3.9E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS03000 003f624229b04776a3c780c315be186a 281 SUPERFAMILY SSF51430 8 274 1.96E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CPF12_RS03000 003f624229b04776a3c780c315be186a 281 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CPF12_RS07460 07d1d8f629012013dd053b8517623902 338 Pfam PF06030 Bacterial protein of unknown function (DUF916) 32 151 3.6E-44 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CPF12_RS07460 07d1d8f629012013dd053b8517623902 338 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 163 299 6.4E-47 T 28-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CPF12_RS07460 07d1d8f629012013dd053b8517623902 338 Gene3D G3DSA:2.60.40.1710 41 167 1.7E-11 T 28-03-2018 CPF12_RS02600 0d0fc03fa8e489cd845a0baf4378b7ac 262 SUPERFAMILY SSF111331 28 260 5.23E-60 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CPF12_RS02600 0d0fc03fa8e489cd845a0baf4378b7ac 262 Hamap MF_00361 NAD kinase [nadK]. 1 262 23.871 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CPF12_RS02600 0d0fc03fa8e489cd845a0baf4378b7ac 262 Pfam PF01513 ATP-NAD kinase 33 226 3.6E-30 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CPF12_RS02600 0d0fc03fa8e489cd845a0baf4378b7ac 262 Gene3D G3DSA:2.60.200.30 117 239 2.1E-26 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CPF12_RS02600 0d0fc03fa8e489cd845a0baf4378b7ac 262 Gene3D G3DSA:3.40.50.10330 1 116 1.3E-23 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CPF12_RS02990 0d08eac2d4ee4996ec1d7e8448bfb6bb 491 Gene3D G3DSA:3.40.605.10 2 266 1.1E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS02990 0d08eac2d4ee4996ec1d7e8448bfb6bb 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CPF12_RS02990 0d08eac2d4ee4996ec1d7e8448bfb6bb 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CPF12_RS02990 0d08eac2d4ee4996ec1d7e8448bfb6bb 491 Gene3D G3DSA:3.40.309.10 267 465 1.6E-71 T 28-03-2018 CPF12_RS02990 0d08eac2d4ee4996ec1d7e8448bfb6bb 491 Pfam PF00171 Aldehyde dehydrogenase family 17 479 1.2E-168 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS02990 0d08eac2d4ee4996ec1d7e8448bfb6bb 491 SUPERFAMILY SSF53720 7 482 4.06E-164 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 SUPERFAMILY SSF74650 381 849 1.0E-34 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 449 846 4.0E-17 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 SUPERFAMILY SSF88688 281 372 1.08E-8 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 3 256 4.6E-32 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 SUPERFAMILY SSF88713 1 267 5.56E-44 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 Pfam PF09261 Alpha mannosidase middle domain 276 351 1.3E-5 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 Gene3D G3DSA:3.20.110.10 1 270 3.9E-45 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 Gene3D G3DSA:2.60.40.1180 364 497 4.9E-7 T 28-03-2018 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 SMART SM00872 274 352 2.1E-4 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CPF12_RS00360 ffaad464803d6551e94b0d207905f1b9 865 Gene3D G3DSA:1.20.1270.50 279 363 9.1E-15 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 Gene3D G3DSA:3.40.50.2300 1 121 4.8E-28 T 28-03-2018 CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 SUPERFAMILY SSF46894 126 224 1.59E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 Pfam PF00072 Response regulator receiver domain 6 113 6.5E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 SMART SM00862 148 223 1.9E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 7.7E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 SUPERFAMILY SSF52172 2 129 1.32E-33 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 Gene3D G3DSA:1.10.10.10 122 228 2.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05005 a4c2a962c3add7b43ee0856129bc0081 228 SMART SM00448 4 114 7.1E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS09165 cb0928e21979cb7ce6e08150a1f29655 346 Gene3D G3DSA:3.20.20.70 1 339 3.3E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS09165 cb0928e21979cb7ce6e08150a1f29655 346 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 322 8.0E-74 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CPF12_RS09165 cb0928e21979cb7ce6e08150a1f29655 346 SUPERFAMILY SSF51395 3 340 2.45E-101 T 28-03-2018 CPF12_RS11825 82096fe7193f56c2735348e029062779 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 124 1.2E-28 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CPF12_RS11825 82096fe7193f56c2735348e029062779 140 Pfam PF03061 Thioesterase superfamily 21 102 3.0E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CPF12_RS11825 82096fe7193f56c2735348e029062779 140 PIRSF PIRSF003230 1 136 7.4E-29 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CPF12_RS11825 82096fe7193f56c2735348e029062779 140 Gene3D G3DSA:3.10.129.10 2 140 2.8E-31 T 28-03-2018 CPF12_RS11825 82096fe7193f56c2735348e029062779 140 SUPERFAMILY SSF54637 4 132 7.23E-34 T 28-03-2018 IPR029069 HotDog domain CPF12_RS05025 498b1e42961351f8af406868be887f67 271 Pfam PF09648 YycH protein 38 251 7.3E-37 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 Gene3D G3DSA:2.30.24.10 1 55 3.9E-19 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 SUPERFAMILY SSF63520 57 164 7.32E-28 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 Pfam PF00874 PRD domain 75 162 2.8E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 Pfam PF00874 PRD domain 183 273 6.1E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 Pfam PF03123 CAT RNA binding domain 4 54 1.7E-16 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 Gene3D G3DSA:1.10.1790.10 56 164 4.1E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 Gene3D G3DSA:1.10.1790.10 165 278 4.6E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 SUPERFAMILY SSF63520 173 275 1.7E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 SUPERFAMILY SSF50151 3 52 8.24E-14 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS10365 fd4a7ede4bd81a373822d0d6ca43e4cd 283 SMART SM01061 2 59 1.4E-18 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CPF12_RS00835 df8f97bfd99efc5c303048918a353a3e 497 PIRSF PIRSF000484 3 483 3.4E-151 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CPF12_RS00835 df8f97bfd99efc5c303048918a353a3e 497 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 158 338 5.2E-10 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CPF12_RS00835 df8f97bfd99efc5c303048918a353a3e 497 SUPERFAMILY SSF51690 141 481 7.51E-128 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CPF12_RS00835 df8f97bfd99efc5c303048918a353a3e 497 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 468 1.4E-175 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CPF12_RS00835 df8f97bfd99efc5c303048918a353a3e 497 Gene3D G3DSA:3.20.140.10 4 390 1.0E-124 T 28-03-2018 CPF12_RS00835 df8f97bfd99efc5c303048918a353a3e 497 SUPERFAMILY SSF54675 5 140 4.32E-47 T 28-03-2018 CPF12_RS02670 de8a24a132df0a7d39abd0168ae49ec6 433 Pfam PF01610 Transposase 168 422 1.8E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS02670 de8a24a132df0a7d39abd0168ae49ec6 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS01080 de8a24a132df0a7d39abd0168ae49ec6 433 Pfam PF01610 Transposase 168 422 1.8E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS01080 de8a24a132df0a7d39abd0168ae49ec6 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS10685 de8a24a132df0a7d39abd0168ae49ec6 433 Pfam PF01610 Transposase 168 422 1.8E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS10685 de8a24a132df0a7d39abd0168ae49ec6 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS10990 4c2be4d92bc735361597529880494949 462 Gene3D G3DSA:1.20.1250.20 236 461 1.0E-34 T 28-03-2018 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 Gene3D G3DSA:1.20.1250.20 1 235 3.0E-35 T 28-03-2018 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 SUPERFAMILY SSF103473 5 451 1.2E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS10990 4c2be4d92bc735361597529880494949 462 Pfam PF00083 Sugar (and other) transporter 15 455 6.9E-112 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 5 450 3.3E-111 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 PRINTS PR00171 Sugar transporter signature 379 391 1.9E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 PRINTS PR00171 Sugar transporter signature 107 126 1.9E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 PRINTS PR00171 Sugar transporter signature 356 377 1.9E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 PRINTS PR00171 Sugar transporter signature 22 32 1.9E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CPF12_RS10990 4c2be4d92bc735361597529880494949 462 PRINTS PR00171 Sugar transporter signature 267 277 1.9E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CPF12_RS04975 ecb6809d14e2320e7a92477a27b5a080 96 SUPERFAMILY SSF46689 10 83 1.08E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS04975 ecb6809d14e2320e7a92477a27b5a080 96 Gene3D G3DSA:1.10.10.60 20 91 4.6E-5 T 28-03-2018 CPF12_RS05045 96e0694830fd88ff679759f2413f321f 312 Gene3D G3DSA:3.40.50.1980 33 151 4.6E-29 T 28-03-2018 CPF12_RS05045 96e0694830fd88ff679759f2413f321f 312 SUPERFAMILY SSF53807 32 297 4.71E-70 T 28-03-2018 CPF12_RS05045 96e0694830fd88ff679759f2413f321f 312 Pfam PF01497 Periplasmic binding protein 53 287 1.7E-37 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CPF12_RS05045 96e0694830fd88ff679759f2413f321f 312 Gene3D G3DSA:3.40.50.1980 152 312 3.4E-35 T 28-03-2018 CPF12_RS08130 9edca8ea8cd889056b701c4679c36e4c 280 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 217 271 9.4E-22 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CPF12_RS08130 9edca8ea8cd889056b701c4679c36e4c 280 PIRSF PIRSF006483 1 279 6.3E-76 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CPF12_RS08130 9edca8ea8cd889056b701c4679c36e4c 280 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 211 2.1E-55 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CPF12_RS09450 a79b305314d8259ef2fdc532e409750c 342 Gene3D G3DSA:1.10.10.10 1 103 0.001 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09450 a79b305314d8259ef2fdc532e409750c 342 Pfam PF14493 Helix-turn-helix domain 254 338 6.1E-12 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Gene3D G3DSA:3.20.20.80 1 117 1.5E-49 T 28-03-2018 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 SMART SM00642 11 419 3.2E-148 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Gene3D G3DSA:3.20.20.80 342 480 7.4E-21 T 28-03-2018 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 SUPERFAMILY SSF51011 480 557 3.78E-13 T 28-03-2018 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Gene3D G3DSA:3.20.20.470 169 341 3.6E-34 T 28-03-2018 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Gene3D G3DSA:2.60.40.1180 481 558 4.3E-17 T 28-03-2018 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 SUPERFAMILY SSF51445 2 477 5.77E-152 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Pfam PF00128 Alpha amylase, catalytic domain 26 376 4.3E-127 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Gene3D G3DSA:3.90.400.10 118 168 1.1E-31 T 28-03-2018 CPF12_RS00900 b5cf88891132e7ec915172b72697a7f9 558 Pfam PF11941 Domain of unknown function (DUF3459) 463 536 1.3E-4 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CPF12_RS01380 58f3a13b21a936fec73fc6fa6ef6da52 174 Pfam PF14317 YcxB-like protein 100 137 8.5E-6 T 28-03-2018 IPR025588 YcxB-like protein CPF12_RS11880 4f331ab6e838a6496e9e3afeb1cba9e1 145 Pfam PF08818 Domain of unknown function (DU1801) 14 129 2.7E-13 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CPF12_RS11880 4f331ab6e838a6496e9e3afeb1cba9e1 145 SUPERFAMILY SSF159888 2 129 1.12E-10 T 28-03-2018 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 Gene3D G3DSA:1.10.260.40 3 56 6.1E-18 T 28-03-2018 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 SUPERFAMILY SSF53822 63 328 1.41E-74 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 7.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 7.6E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.9E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 SUPERFAMILY SSF47413 2 61 1.05E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 Gene3D G3DSA:3.40.50.2300 57 177 6.3E-31 T 28-03-2018 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 Pfam PF13377 Periplasmic binding protein-like domain 172 328 1.4E-34 T 28-03-2018 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 SMART SM00354 2 73 6.9E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CPF12_RS01720 95da1c60632adcfc327ec370d762af17 333 Gene3D G3DSA:3.40.50.2300 178 311 8.0E-39 T 28-03-2018 CPF12_RS03010 b7f1fc9992e1c4441f9be0c6b073300e 176 Gene3D G3DSA:3.40.50.360 2 176 5.2E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS03010 b7f1fc9992e1c4441f9be0c6b073300e 176 SUPERFAMILY SSF52218 12 169 3.57E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS03010 b7f1fc9992e1c4441f9be0c6b073300e 176 Pfam PF03358 NADPH-dependent FMN reductase 2 143 6.4E-27 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 2.3E-148 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 Pfam PF03129 Anticodon binding domain 331 420 9.0E-14 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 32.492 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 Gene3D G3DSA:3.30.930.10 1 323 2.2E-71 T 28-03-2018 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 SUPERFAMILY SSF55681 2 318 2.11E-97 T 28-03-2018 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 PIRSF PIRSF001549 1 422 2.6E-116 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 Pfam PF13393 Histidyl-tRNA synthetase 8 313 3.3E-45 T 28-03-2018 CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 Gene3D G3DSA:3.40.50.800 327 425 2.6E-16 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS01780 45e2f3144be9cb24f3063492f79e38f6 428 SUPERFAMILY SSF52954 329 420 1.64E-21 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 Gene3D G3DSA:3.40.630.10 172 355 3.3E-40 T 28-03-2018 CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 1.2E-99 T 28-03-2018 IPR008007 Peptidase M42 CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 Gene3D G3DSA:2.40.30.40 69 161 8.5E-27 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 SUPERFAMILY SSF53187 172 348 2.25E-66 T 28-03-2018 CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 SUPERFAMILY SSF53187 5 80 2.25E-66 T 28-03-2018 CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 SUPERFAMILY SSF101821 70 180 2.59E-25 T 28-03-2018 CPF12_RS08640 534e91218f5786307b70dabb7ddda12a 357 PIRSF PIRSF001123 2 356 1.7E-135 T 28-03-2018 IPR008007 Peptidase M42 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 Gene3D G3DSA:3.30.390.30 336 462 2.8E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 SUPERFAMILY SSF51905 9 339 3.11E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 1.4E-31 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 329 2.2E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 3.4E-74 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.1E-39 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.1E-39 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.1E-39 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.1E-39 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.1E-39 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 PIRSF PIRSF000350 4 459 3.2E-90 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 Gene3D G3DSA:3.50.50.60 9 159 6.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 SUPERFAMILY SSF55424 344 467 4.12E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 Gene3D G3DSA:3.40.50.720 160 335 3.0E-37 T 28-03-2018 CPF12_RS02190 4b9fc9511f5941efffccfded53aa2803 467 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 11 467 1.1E-164 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CPF12_RS10415 c907e0661fbb3289a68cf685f6cfe5f3 120 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 18 110 2.6E-14 T 28-03-2018 IPR014913 Protein of unknown function DUF1798 CPF12_RS10415 c907e0661fbb3289a68cf685f6cfe5f3 120 Gene3D G3DSA:1.20.120.440 2 115 1.7E-22 T 28-03-2018 IPR023351 YppE-like domain CPF12_RS10415 c907e0661fbb3289a68cf685f6cfe5f3 120 SUPERFAMILY SSF140415 16 115 3.14E-19 T 28-03-2018 IPR023351 YppE-like domain CPF12_RS09950 4346122644578fc1a36d929e0cafb1cc 875 Gene3D G3DSA:3.40.630.30 542 631 0.28 T 28-03-2018 CPF12_RS09950 4346122644578fc1a36d929e0cafb1cc 875 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 205 296 3.1E-10 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CPF12_RS09950 4346122644578fc1a36d929e0cafb1cc 875 SUPERFAMILY SSF55729 640 819 1.94E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS09950 4346122644578fc1a36d929e0cafb1cc 875 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 531 822 1.1E-88 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CPF12_RS09950 4346122644578fc1a36d929e0cafb1cc 875 Gene3D G3DSA:3.40.630.30 632 815 1.4E-12 T 28-03-2018 CPF12_RS09875 f24c551815752023da5e35ceadf4debc 215 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 182 197 3.0E-4 T 28-03-2018 IPR017502 Sortase B cell surface sorting signal CPF12_RS09875 f24c551815752023da5e35ceadf4debc 215 Pfam PF05031 Iron Transport-associated domain 29 140 2.9E-29 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09875 f24c551815752023da5e35ceadf4debc 215 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 183 211 2.8E-4 T 28-03-2018 CPF12_RS09875 f24c551815752023da5e35ceadf4debc 215 SMART SM00725 29 148 1.5E-37 T 28-03-2018 IPR006635 NEAT domain CPF12_RS09875 f24c551815752023da5e35ceadf4debc 215 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 1 213 5.8E-65 T 28-03-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 CPF12_RS09875 f24c551815752023da5e35ceadf4debc 215 SUPERFAMILY SSF158911 31 140 6.54E-31 T 28-03-2018 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 PRINTS PR00340 P-II protein signature 8 23 8.3E-23 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 PRINTS PR00340 P-II protein signature 89 109 8.3E-23 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 PRINTS PR00340 P-II protein signature 29 47 8.3E-23 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 PRINTS PR00340 P-II protein signature 58 81 8.3E-23 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 SMART SM00938 10 111 1.6E-32 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 SUPERFAMILY SSF54913 9 118 5.08E-31 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 Pfam PF00543 Nitrogen regulatory protein P-II 10 111 2.5E-29 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 ProSitePatterns PS00638 P-II protein C-terminal region signature. 89 102 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CPF12_RS08665 41fa21247c89cff386045dc791a741c7 118 Gene3D G3DSA:3.30.70.120 1 115 4.4E-35 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CPF12_RS06060 d8f3a5dd4ce87f8f627d3c852232850f 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 5.6E-87 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06060 d8f3a5dd4ce87f8f627d3c852232850f 208 Pfam PF00297 Ribosomal protein L3 100 181 7.5E-16 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06060 d8f3a5dd4ce87f8f627d3c852232850f 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CPF12_RS06060 d8f3a5dd4ce87f8f627d3c852232850f 208 Gene3D G3DSA:4.10.960.10 58 164 1.5E-33 T 28-03-2018 CPF12_RS06060 d8f3a5dd4ce87f8f627d3c852232850f 208 SUPERFAMILY SSF50447 1 207 1.68E-81 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CPF12_RS06060 d8f3a5dd4ce87f8f627d3c852232850f 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 38.675 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 Pfam PF16592 REC lobe of CRISPR-associated endonuclease Cas9 187 729 4.7E-134 T 28-03-2018 IPR032240 CRISPR-associated endonuclease Cas9, REC lobe CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 Gene3D G3DSA:3.40.1800.10 820 897 1.5E-7 T 28-03-2018 CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 TIGRFAM TIGR01865 cas_Csn1: CRISPR subtype II RNA-guided endonuclease Cas9 8 1040 2.1E-189 T 28-03-2018 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 Hamap MF_01480 CRISPR-associated endonuclease Cas9 [cas9]. 7 1333 14.515 T 28-03-2018 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 Gene3D G3DSA:3.30.420.40 2 58 0.001 T 28-03-2018 CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 Pfam PF16595 PAM-interacting domain of CRISPR-associated endonuclease Cas9 1088 1332 3.1E-51 T 28-03-2018 IPR032237 CRISPR-associated endonuclease Cas9, PAM-interacting domain CPF12_RS12285 fa0a47052803c4982fcfb02e6a41d0b1 1339 Pfam PF13395 HNH endonuclease 842 890 3.1E-15 T 28-03-2018 IPR003615 HNH nuclease CPF12_RS08015 e1a2f8731693685731a10b1e799d5e6b 202 SMART SM00530 5 61 5.7E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS08015 e1a2f8731693685731a10b1e799d5e6b 202 SUPERFAMILY SSF47413 2 66 2.34E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS08015 e1a2f8731693685731a10b1e799d5e6b 202 Gene3D G3DSA:1.10.260.40 1 184 3.7E-11 T 28-03-2018 CPF12_RS08015 e1a2f8731693685731a10b1e799d5e6b 202 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 66 2.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS00375 dfd200019c09f1e9493ed90a619c47bc 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 149 7.9E-39 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS00375 dfd200019c09f1e9493ed90a619c47bc 152 SUPERFAMILY SSF55804 1 149 1.7E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS00375 dfd200019c09f1e9493ed90a619c47bc 152 Gene3D G3DSA:3.40.930.10 1 151 1.5E-41 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS00375 dfd200019c09f1e9493ed90a619c47bc 152 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 134 2.0E-39 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CPF12_RS00375 dfd200019c09f1e9493ed90a619c47bc 152 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS10930 005839ef0d663ec9dd0f4c529e846de6 94 Pfam PF00581 Rhodanese-like domain 4 87 2.3E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS10930 005839ef0d663ec9dd0f4c529e846de6 94 Gene3D G3DSA:3.40.250.10 2 93 2.4E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS10930 005839ef0d663ec9dd0f4c529e846de6 94 SMART SM00450 1 93 9.5E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS10930 005839ef0d663ec9dd0f4c529e846de6 94 SUPERFAMILY SSF52821 6 88 1.26E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS06780 f141f69531c44c5ae17bbf44faedc3c3 491 SUPERFAMILY SSF53720 13 487 1.83E-166 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS06780 f141f69531c44c5ae17bbf44faedc3c3 491 Gene3D G3DSA:3.40.605.10 9 275 1.0E-100 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS06780 f141f69531c44c5ae17bbf44faedc3c3 491 Gene3D G3DSA:3.40.309.10 276 471 6.8E-71 T 28-03-2018 CPF12_RS06780 f141f69531c44c5ae17bbf44faedc3c3 491 Pfam PF00171 Aldehyde dehydrogenase family 23 484 7.2E-171 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS10635 f3ce3c783c6353ac90caa80041104434 211 SUPERFAMILY SSF52540 4 209 1.05E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10635 f3ce3c783c6353ac90caa80041104434 211 Gene3D G3DSA:3.40.50.300 1 211 1.3E-57 T 28-03-2018 CPF12_RS10635 f3ce3c783c6353ac90caa80041104434 211 Pfam PF00005 ABC transporter 19 168 3.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS10635 f3ce3c783c6353ac90caa80041104434 211 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS10635 f3ce3c783c6353ac90caa80041104434 211 SMART SM00382 27 207 6.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07255 cddd4073d87103a9936984037da295b7 86 SUPERFAMILY SSF46785 15 78 8.65E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07255 cddd4073d87103a9936984037da295b7 86 Gene3D G3DSA:1.10.10.10 3 78 4.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09620 fe0310ad658323303f23aed818672690 372 SUPERFAMILY SSF52402 8 247 1.01E-60 T 28-03-2018 CPF12_RS09620 fe0310ad658323303f23aed818672690 372 Gene3D G3DSA:2.30.30.280 216 279 1.8E-29 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CPF12_RS09620 fe0310ad658323303f23aed818672690 372 Gene3D G3DSA:2.40.30.10 281 371 2.2E-29 T 28-03-2018 CPF12_RS09620 fe0310ad658323303f23aed818672690 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 359 40.978 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CPF12_RS09620 fe0310ad658323303f23aed818672690 372 Pfam PF03054 tRNA methyl transferase 10 358 5.2E-150 T 28-03-2018 CPF12_RS09620 fe0310ad658323303f23aed818672690 372 Gene3D G3DSA:3.40.50.620 1 215 1.7E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS09620 fe0310ad658323303f23aed818672690 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 10 358 6.7E-140 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 Gene3D G3DSA:3.10.180.10 167 279 1.6E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 169 217 1.3E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 122 2.3E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 102 121 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 SUPERFAMILY SSF54593 5 168 6.2E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 SUPERFAMILY SSF54593 165 276 1.04E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS06355 d0ae06ecdfcbf64b38f62e1f6f342142 283 Gene3D G3DSA:3.10.180.10 7 166 1.9E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS04980 b01a73a70f73ce6263575d0bfc96827d 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 6.4E-56 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS04980 b01a73a70f73ce6263575d0bfc96827d 159 PIRSF PIRSF004505 1 159 1.7E-51 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS04980 b01a73a70f73ce6263575d0bfc96827d 159 Gene3D G3DSA:3.40.1280.10 1 159 1.1E-59 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CPF12_RS04980 b01a73a70f73ce6263575d0bfc96827d 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 2.4E-56 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS04980 b01a73a70f73ce6263575d0bfc96827d 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 28.72 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CPF12_RS04980 b01a73a70f73ce6263575d0bfc96827d 159 SUPERFAMILY SSF75217 2 157 4.64E-56 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CPF12_RS00120 271677bfca70ebb649184271052f3a1d 147 Gene3D G3DSA:3.90.1720.10 23 147 6.2E-33 T 28-03-2018 CPF12_RS00120 271677bfca70ebb649184271052f3a1d 147 Pfam PF00877 NlpC/P60 family 42 142 2.2E-28 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CPF12_RS00120 271677bfca70ebb649184271052f3a1d 147 SUPERFAMILY SSF54001 23 143 5.4E-35 T 28-03-2018 CPF12_RS03650 1c546ff00bf1ddc83ecc6ad270d6b6e8 390 SUPERFAMILY SSF53383 6 387 4.08E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS03650 1c546ff00bf1ddc83ecc6ad270d6b6e8 390 Gene3D G3DSA:3.40.640.10 47 298 3.1E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS03650 1c546ff00bf1ddc83ecc6ad270d6b6e8 390 Pfam PF00155 Aminotransferase class I and II 34 370 8.0E-59 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS03650 1c546ff00bf1ddc83ecc6ad270d6b6e8 390 Gene3D G3DSA:3.90.1150.10 299 387 6.2E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS04425 b9854947fdb50da871745b8b65e26945 344 SUPERFAMILY SSF53850 33 338 3.65E-67 T 28-03-2018 CPF12_RS04425 b9854947fdb50da871745b8b65e26945 344 Gene3D G3DSA:3.40.190.10 138 303 4.6E-33 T 28-03-2018 CPF12_RS04425 b9854947fdb50da871745b8b65e26945 344 Pfam PF13343 Bacterial extracellular solute-binding protein 85 307 8.5E-27 T 28-03-2018 CPF12_RS04425 b9854947fdb50da871745b8b65e26945 344 PIRSF PIRSF002825 1 340 1.9E-63 T 28-03-2018 IPR026045 Ferric binding protein CPF12_RS04425 b9854947fdb50da871745b8b65e26945 344 Gene3D G3DSA:3.40.190.10 29 137 5.8E-11 T 28-03-2018 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 SUPERFAMILY SSF55874 305 453 7.86E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 SMART SM00304 181 233 3.2E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 SUPERFAMILY SSF47384 217 298 1.02E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 Gene3D G3DSA:3.30.565.10 304 455 5.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 SMART SM00388 234 300 3.2E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 7.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 7.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 7.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 7.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 SUPERFAMILY SSF158472 181 228 2.88E-10 T 28-03-2018 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 453 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 2.8E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 SMART SM00387 344 455 8.1E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 Gene3D G3DSA:1.10.287.130 224 295 4.8E-18 T 28-03-2018 CPF12_RS08550 213e0f5b0084c0ddfba05c589a572e23 455 Pfam PF00672 HAMP domain 181 228 3.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 384 429 7.3E-16 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 SUPERFAMILY SSF52402 12 226 8.6E-55 T 28-03-2018 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 SUPERFAMILY SSF56037 363 449 1.23E-15 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 3 318 24.383 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 Pfam PF01171 PP-loop family 23 204 2.6E-56 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 Pfam PF11734 TilS substrate C-terminal domain 385 452 7.6E-13 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 SMART SM00977 384 459 3.3E-18 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 Gene3D G3DSA:3.40.50.620 15 232 2.4E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS05805 b08129a0dbd5e1afcfe2e3264edc3135 462 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 22 208 1.3E-59 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CPF12_RS06625 d2e8a349a898c9b9f4d5759ea764875f 280 Gene3D G3DSA:3.30.1180.10 151 280 1.6E-37 T 28-03-2018 CPF12_RS06625 d2e8a349a898c9b9f4d5759ea764875f 280 Gene3D G3DSA:3.40.50.10440 54 150 3.5E-33 T 28-03-2018 CPF12_RS06625 d2e8a349a898c9b9f4d5759ea764875f 280 Gene3D G3DSA:2.20.28.50 28 53 6.5E-15 T 28-03-2018 CPF12_RS06625 d2e8a349a898c9b9f4d5759ea764875f 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 7.4E-98 T 28-03-2018 IPR003797 DegV CPF12_RS06625 d2e8a349a898c9b9f4d5759ea764875f 280 SUPERFAMILY SSF82549 1 280 9.94E-88 T 28-03-2018 CPF12_RS06625 d2e8a349a898c9b9f4d5759ea764875f 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 278 1.3E-89 T 28-03-2018 IPR003797 DegV CPF12_RS11685 ee8cafba74a57edc937f382b356250ab 196 Pfam PF12730 ABC-2 family transporter protein 5 178 7.4E-11 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CPF12_RS08970 9e9a73875ec807aad7ba08cb65171146 640 Pfam PF02687 FtsX-like permease family 84 175 3.1E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS08970 9e9a73875ec807aad7ba08cb65171146 640 PIRSF PIRSF018968 1 633 3.1E-92 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 Pfam PF03449 Transcription elongation factor, N-terminal 21 90 2.3E-30 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 PIRSF PIRSF006092 14 172 2.1E-51 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 SUPERFAMILY SSF46557 19 94 1.96E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 33 64 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 Gene3D G3DSA:1.10.287.180 19 92 4.6E-31 T 28-03-2018 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 Hamap MF_00105 Transcription elongation factor GreA [greA]. 18 171 32.517 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 SUPERFAMILY SSF54534 97 170 5.76E-21 T 28-03-2018 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 Gene3D G3DSA:3.10.50.30 93 172 3.7E-26 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 21 171 2.5E-57 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 136 152 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CPF12_RS09705 2b0c3deee4640359eb6c5d7f22218eeb 172 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 98 171 2.2E-27 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CPF12_RS12355 e848ec967246149d10357c0b5850f9b3 197 Gene3D G3DSA:1.10.530.10 43 197 1.2E-30 T 28-03-2018 CPF12_RS12355 e848ec967246149d10357c0b5850f9b3 197 SUPERFAMILY SSF53955 40 102 2.4E-32 T 28-03-2018 IPR023346 Lysozyme-like domain CPF12_RS12355 e848ec967246149d10357c0b5850f9b3 197 SUPERFAMILY SSF53955 129 194 2.4E-32 T 28-03-2018 IPR023346 Lysozyme-like domain CPF12_RS12355 e848ec967246149d10357c0b5850f9b3 197 Pfam PF13406 Transglycosylase SLT domain 127 159 7.2E-7 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CPF12_RS01270 cccc6bdfc94597db65c312c2dfe8aef2 54 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 7 45 1.7E-6 T 28-03-2018 IPR010022 Protein of unknown function XkdX CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 105 115 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 330 341 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 Gene3D G3DSA:3.40.50.300 13 235 6.9E-88 T 28-03-2018 CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 Gene3D G3DSA:3.40.50.300 236 444 5.2E-67 T 28-03-2018 CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 SUPERFAMILY SSF52540 5 556 2.86E-238 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 2 558 48.024 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 Pfam PF01268 Formate--tetrahydrofolate ligase 4 558 4.6E-264 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CPF12_RS10550 abb148344f7acd1ebaa649125dd1d1a7 558 Gene3D G3DSA:3.10.410.10 446 534 9.9E-38 T 28-03-2018 CPF12_RS08225 e26451be302fba25c32a68b7f0572237 240 Gene3D G3DSA:3.40.50.880 1 239 9.2E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS08225 e26451be302fba25c32a68b7f0572237 240 SUPERFAMILY SSF52317 25 237 2.07E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS08225 e26451be302fba25c32a68b7f0572237 240 Pfam PF07722 Peptidase C26 4 218 7.2E-65 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 SMART SM00382 29 212 4.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 Pfam PF03459 TOBE domain 296 333 3.2E-6 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 SUPERFAMILY SSF52540 4 243 1.14E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 Gene3D G3DSA:2.40.50.100 240 291 3.5E-12 T 28-03-2018 CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 SUPERFAMILY SSF50331 237 362 6.32E-27 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 Gene3D G3DSA:2.40.50.140 292 347 2.3E-11 T 28-03-2018 CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 Gene3D G3DSA:3.40.50.300 1 237 7.5E-73 T 28-03-2018 CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 Pfam PF00005 ABC transporter 21 162 3.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07720 d4f0c8fff4f7166134db85d32c790e8a 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11130 94266f98ea99ecb49f1829d73f2249ac 90 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.936 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CPF12_RS11130 94266f98ea99ecb49f1829d73f2249ac 90 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 2.0E-20 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CPF12_RS11130 94266f98ea99ecb49f1829d73f2249ac 90 Pfam PF01809 Haemolytic domain 2 68 8.7E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CPF12_RS11130 94266f98ea99ecb49f1829d73f2249ac 90 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 71 1.3E-32 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CPF12_RS11130 94266f98ea99ecb49f1829d73f2249ac 90 SMART SM01234 1 68 2.1E-44 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CPF12_RS08610 1afd552c0bbcf90987351a2f50ac08c3 147 SUPERFAMILY SSF54631 14 138 7.58E-27 T 28-03-2018 CPF12_RS08610 1afd552c0bbcf90987351a2f50ac08c3 147 Pfam PF00571 CBS domain 85 137 1.2E-5 T 28-03-2018 IPR000644 CBS domain CPF12_RS08610 1afd552c0bbcf90987351a2f50ac08c3 147 Pfam PF00571 CBS domain 18 60 4.8E-4 T 28-03-2018 IPR000644 CBS domain CPF12_RS08610 1afd552c0bbcf90987351a2f50ac08c3 147 Gene3D G3DSA:3.10.580.10 3 147 2.8E-17 T 28-03-2018 CPF12_RS08605 874f0a7e98bd3074b9550833e9600a9f 77 PIRSF PIRSF037356 1 74 7.7E-29 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 CPF12_RS08605 874f0a7e98bd3074b9550833e9600a9f 77 Pfam PF08796 Protein of unknown function (DUF1797) 7 73 2.0E-27 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 CPF12_RS08605 874f0a7e98bd3074b9550833e9600a9f 77 SUPERFAMILY SSF143567 2 74 1.96E-25 T 28-03-2018 CPF12_RS00155 ab4935d95b8aa0220626332f6373bbb2 149 Gene3D G3DSA:2.60.120.10 9 149 3.4E-27 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS00155 ab4935d95b8aa0220626332f6373bbb2 149 Pfam PF06249 Ethanolamine utilisation protein EutQ 9 146 2.0E-59 T 28-03-2018 IPR010424 Ethanolamine utilisation EutQ CPF12_RS00155 ab4935d95b8aa0220626332f6373bbb2 149 SUPERFAMILY SSF51182 49 146 1.24E-21 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS01685 19511226cb4200a428d6209957dc4dcc 103 Pfam PF01381 Helix-turn-helix 6 60 3.6E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS01685 19511226cb4200a428d6209957dc4dcc 103 SUPERFAMILY SSF47413 2 64 1.26E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS01685 19511226cb4200a428d6209957dc4dcc 103 Gene3D G3DSA:1.10.260.40 1 59 1.1E-20 T 28-03-2018 CPF12_RS01685 19511226cb4200a428d6209957dc4dcc 103 Gene3D G3DSA:1.20.5.1180 60 98 0.0014 T 28-03-2018 CPF12_RS01685 19511226cb4200a428d6209957dc4dcc 103 SMART SM00530 5 60 1.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS11035 507a417376a56c13a2e06ce0025057bf 337 Gene3D G3DSA:3.40.50.300 19 336 7.3E-34 T 28-03-2018 CPF12_RS11035 507a417376a56c13a2e06ce0025057bf 337 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 29 176 1.8E-17 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CPF12_RS11035 507a417376a56c13a2e06ce0025057bf 337 Pfam PF01926 50S ribosome-binding GTPase 30 138 1.2E-15 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS11035 507a417376a56c13a2e06ce0025057bf 337 Pfam PF05128 Domain of unknown function (DUF697) 193 331 1.5E-13 T 28-03-2018 IPR021147 Protein of unknown function DUF697 CPF12_RS11035 507a417376a56c13a2e06ce0025057bf 337 SUPERFAMILY SSF52540 17 185 9.06E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 PRINTS PR00050 Cold shock protein signature 39 57 3.4E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 PRINTS PR00050 Cold shock protein signature 24 33 3.4E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 PRINTS PR00050 Cold shock protein signature 4 19 3.4E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 Gene3D G3DSA:2.40.50.140 1 66 3.5E-29 T 28-03-2018 CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 PIRSF PIRSF002599 1 66 2.6E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 SUPERFAMILY SSF50249 1 63 4.07E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.4E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CPF12_RS03685 54584296d07321d6abf951137fa222ef 66 SMART SM00357 3 66 7.7E-32 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 1.7E-18 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 SUPERFAMILY SSF53597 149 347 3.8E-42 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 PIRSF PIRSF006769 1 354 4.2E-99 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 SUPERFAMILY SSF53927 3 143 3.41E-40 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 Gene3D G3DSA:3.40.140.10 1 126 1.1E-32 T 28-03-2018 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 Gene3D G3DSA:3.40.430.10 127 354 5.5E-53 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 Pfam PF01872 RibD C-terminal domain 149 346 4.0E-40 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 90 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CPF12_RS04820 2def0613cf2abe914f9577be7cc97fdd 372 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 347 8.0E-96 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 SUPERFAMILY SSF52172 1 186 2.28E-52 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 Pfam PF00072 Response regulator receiver domain 5 114 9.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 PIRSF PIRSF036382 1 190 1.5E-66 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 Pfam PF03861 ANTAR domain 134 186 2.8E-17 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 SMART SM01012 131 186 1.1E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 Gene3D G3DSA:1.10.10.10 136 188 3.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 Gene3D G3DSA:3.40.50.2300 2 135 9.7E-35 T 28-03-2018 CPF12_RS00220 cdda942ee6423e34d149776a2a8e41e9 190 SMART SM00448 3 115 1.4E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS01095 17a87c96e294057344a9babd8754c127 183 Pfam PF04093 rod shape-determining protein MreD 7 167 7.7E-17 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CPF12_RS01095 17a87c96e294057344a9babd8754c127 183 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 15 162 1.6E-16 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CPF12_RS01450 c666780ff595bea4ccf26425eb6dff3e 308 Gene3D G3DSA:2.40.50.140 74 229 1.9E-10 T 28-03-2018 CPF12_RS01450 c666780ff595bea4ccf26425eb6dff3e 308 Pfam PF13509 S1 domain 10 71 1.5E-6 T 28-03-2018 CPF12_RS01450 c666780ff595bea4ccf26425eb6dff3e 308 PIRSF PIRSF012524 6 292 9.8E-101 T 28-03-2018 IPR014464 Conserved virulence factor B CPF12_RS01450 c666780ff595bea4ccf26425eb6dff3e 308 Gene3D G3DSA:1.10.10.10 231 290 8.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00670 86655a9b03ea4e3db3da4954b9912052 190 Gene3D G3DSA:3.40.47.10 8 155 4.3E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS00670 86655a9b03ea4e3db3da4954b9912052 190 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 31 148 9.6E-5 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CPF12_RS00670 86655a9b03ea4e3db3da4954b9912052 190 SUPERFAMILY SSF53901 16 149 1.69E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 SUPERFAMILY SSF55826 218 387 6.15E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 Gene3D G3DSA:3.30.930.10 11 457 6.4E-98 T 28-03-2018 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 39.091 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 Gene3D G3DSA:3.40.50.800 458 566 5.0E-25 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 SUPERFAMILY SSF52954 460 565 1.8E-24 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 Pfam PF03129 Anticodon binding domain 473 563 4.6E-15 T 28-03-2018 IPR004154 Anticodon-binding CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 SUPERFAMILY SSF55681 9 237 3.45E-98 T 28-03-2018 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 SUPERFAMILY SSF55681 404 474 3.45E-98 T 28-03-2018 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 8.5E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 8.5E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 8.5E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 8.5E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 2.3E-51 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 563 8.1E-220 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CPF12_RS12305 a7c809928088bd2288f901cf26b5a241 566 Pfam PF04073 Aminoacyl-tRNA editing domain 257 372 1.1E-23 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CPF12_RS02845 443c45f1bc512d23a2f4b14200a22cf6 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 4 380 3.2E-108 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CPF12_RS02845 443c45f1bc512d23a2f4b14200a22cf6 403 PIRSF PIRSF037259 1 400 1.5E-111 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CPF12_RS05400 636202c6d6629ef3b912bde5d621791a 181 Pfam PF01381 Helix-turn-helix 17 71 7.6E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05400 636202c6d6629ef3b912bde5d621791a 181 Gene3D G3DSA:1.10.3100.10 9 128 1.0E-23 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS05400 636202c6d6629ef3b912bde5d621791a 181 SUPERFAMILY SSF47413 11 76 1.21E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05400 636202c6d6629ef3b912bde5d621791a 181 SMART SM00530 16 71 1.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS03305 29605e5c830cca16862e3905f44cfad0 279 SUPERFAMILY SSF53474 34 64 6.17E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS03305 29605e5c830cca16862e3905f44cfad0 279 SUPERFAMILY SSF53474 96 177 6.17E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS03305 29605e5c830cca16862e3905f44cfad0 279 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 36 278 1.0E-51 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CPF12_RS03305 29605e5c830cca16862e3905f44cfad0 279 Gene3D G3DSA:3.40.50.1820 36 278 3.6E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 PIRSF PIRSF000151 1 414 2.7E-176 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 SUPERFAMILY SSF53720 3 413 1.22E-107 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 320 341 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 413 41.058 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 Gene3D G3DSA:3.40.605.10 239 414 2.2E-41 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 Pfam PF00171 Aldehyde dehydrogenase family 39 281 1.2E-13 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 403 1.3E-157 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CPF12_RS08195 99f196f2cc4755b0621fdea9ca71ace7 414 Gene3D G3DSA:3.40.605.10 1 238 8.8E-36 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS04470 75e9ca46ad679b4e497276889aacf0ed 178 Gene3D G3DSA:3.40.630.30 5 166 4.2E-20 T 28-03-2018 CPF12_RS04470 75e9ca46ad679b4e497276889aacf0ed 178 SUPERFAMILY SSF55729 3 154 2.62E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS04470 75e9ca46ad679b4e497276889aacf0ed 178 Pfam PF00583 Acetyltransferase (GNAT) family 34 142 1.3E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS00780 511f23381e82f98a05fc254a2a6a1a00 473 SUPERFAMILY SSF103473 8 200 5.49E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS00780 511f23381e82f98a05fc254a2a6a1a00 473 SUPERFAMILY SSF103473 254 468 5.49E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS00780 511f23381e82f98a05fc254a2a6a1a00 473 Pfam PF07690 Major Facilitator Superfamily 22 413 3.8E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS00780 511f23381e82f98a05fc254a2a6a1a00 473 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 442 2.8E-80 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS00780 511f23381e82f98a05fc254a2a6a1a00 473 Gene3D G3DSA:1.20.1250.20 2 202 2.0E-29 T 28-03-2018 CPF12_RS00780 511f23381e82f98a05fc254a2a6a1a00 473 Gene3D G3DSA:1.20.1250.20 265 471 1.5E-26 T 28-03-2018 CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 SUPERFAMILY SSF109755 4 218 1.36E-49 T 28-03-2018 CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 PIRSF PIRSF003107 1 220 1.7E-50 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 Pfam PF01895 PhoU domain 125 206 2.6E-7 T 28-03-2018 IPR026022 PhoU domain CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 Pfam PF01895 PhoU domain 18 105 2.9E-22 T 28-03-2018 IPR026022 PhoU domain CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 214 6.2E-52 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 Gene3D G3DSA:1.20.58.220 117 221 2.5E-13 T 28-03-2018 CPF12_RS06720 defddb0ced62c4f45042a618d699349b 221 Gene3D G3DSA:1.20.58.220 1 114 3.0E-24 T 28-03-2018 CPF12_RS06680 cdc9e8f89fe486f89414af0bbe4945aa 402 SUPERFAMILY SSF50156 307 389 1.73E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CPF12_RS06680 cdc9e8f89fe486f89414af0bbe4945aa 402 Gene3D G3DSA:2.30.42.10 289 367 4.8E-7 T 28-03-2018 CPF12_RS06525 c68438dce4a8b342dfff9756c5829771 243 Gene3D G3DSA:3.40.50.720 69 203 0.0064 T 28-03-2018 CPF12_RS06525 c68438dce4a8b342dfff9756c5829771 243 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 227 4.0E-56 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CPF12_RS06525 c68438dce4a8b342dfff9756c5829771 243 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 57 233 6.8E-52 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CPF12_RS11535 b2422050fc773e6c6510664be451a14b 78 Hamap MF_01217 Acyl carrier protein [acpP]. 4 78 20.587 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CPF12_RS11535 b2422050fc773e6c6510664be451a14b 78 Pfam PF00550 Phosphopantetheine attachment site 7 74 8.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS11535 b2422050fc773e6c6510664be451a14b 78 Gene3D G3DSA:1.10.1200.10 3 78 1.3E-19 T 28-03-2018 CPF12_RS11535 b2422050fc773e6c6510664be451a14b 78 SUPERFAMILY SSF47336 3 76 2.75E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS11535 b2422050fc773e6c6510664be451a14b 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 3 77 2.5E-27 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CPF12_RS11535 b2422050fc773e6c6510664be451a14b 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 35 74 3.0E-7 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 Pfam PF00206 Lyase 14 339 8.9E-81 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 SUPERFAMILY SSF48557 2 440 4.12E-127 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 Gene3D G3DSA:1.10.40.30 412 450 5.4E-10 T 28-03-2018 CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 Gene3D G3DSA:1.10.275.10 1 135 4.3E-48 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 Gene3D G3DSA:1.20.200.10 136 411 2.3E-66 T 28-03-2018 CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.7E-26 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 1.7E-26 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 1.7E-26 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 1.7E-26 T 28-03-2018 IPR000362 Fumarate lyase family CPF12_RS00755 fe5053d56e4bace8a90a60d8f45e542d 450 Pfam PF10415 Fumarase C C-terminus 407 443 2.2E-9 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CPF12_RS02380 5a8746af5d39342aa7e9dca3b0178460 154 Gene3D G3DSA:2.70.40.10 4 154 8.8E-33 T 28-03-2018 CPF12_RS02380 5a8746af5d39342aa7e9dca3b0178460 154 SUPERFAMILY SSF51283 20 152 8.37E-29 T 28-03-2018 IPR029054 dUTPase-like CPF12_RS02380 5a8746af5d39342aa7e9dca3b0178460 154 Pfam PF00692 dUTPase 21 151 9.2E-17 T 28-03-2018 IPR029054 dUTPase-like CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 Pfam PF03793 PASTA domain 598 652 1.9E-5 T 28-03-2018 IPR005543 PASTA domain CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 Pfam PF03793 PASTA domain 656 709 3.9E-11 T 28-03-2018 IPR005543 PASTA domain CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 SUPERFAMILY SSF56601 194 611 1.71E-85 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 SMART SM00740 594 654 8.1E-6 T 28-03-2018 IPR005543 PASTA domain CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 SMART SM00740 655 711 9.2E-9 T 28-03-2018 IPR005543 PASTA domain CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 Gene3D G3DSA:3.40.710.10 240 584 1.3E-77 T 28-03-2018 CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 225 1.5E-21 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 Gene3D G3DSA:3.90.1310.10 24 239 1.0E-34 T 28-03-2018 CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 SUPERFAMILY SSF56519 56 242 1.18E-39 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 SUPERFAMILY SSF54184 598 653 1.44E-12 T 28-03-2018 CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 578 1.5E-79 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CPF12_RS02035 c1ddb1f8fe8fa95651d524d92cee1eea 749 SUPERFAMILY SSF54184 656 710 1.28E-12 T 28-03-2018 CPF12_RS11690 cc32d5d6ca94a038a3d61f906cc29abf 247 Pfam PF12730 ABC-2 family transporter protein 6 184 2.6E-18 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 609 715 2.9E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 SUPERFAMILY SSF55874 551 703 9.69E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 Gene3D G3DSA:1.20.1250.20 253 489 2.4E-5 T 28-03-2018 CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 SMART SM00387 608 719 3.6E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 Gene3D G3DSA:1.10.287.130 490 558 6.1E-17 T 28-03-2018 CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 Gene3D G3DSA:3.30.565.10 566 726 1.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 Pfam PF00512 His Kinase A (phospho-acceptor) domain 497 562 2.0E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 SMART SM00388 496 562 6.0E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS08770 99f0e72aca3c07731fa8ae73eb438d52 727 SUPERFAMILY SSF47384 479 562 9.61E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS03670 be2b9f80d5ae4f0c8413dcfd7ba70a40 185 Gene3D G3DSA:1.10.10.10 1 63 4.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03670 be2b9f80d5ae4f0c8413dcfd7ba70a40 185 SUPERFAMILY SSF160387 87 177 2.09E-14 T 28-03-2018 CPF12_RS03670 be2b9f80d5ae4f0c8413dcfd7ba70a40 185 SMART SM00420 6 58 8.6E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS03670 be2b9f80d5ae4f0c8413dcfd7ba70a40 185 SUPERFAMILY SSF46785 4 62 6.02E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03670 be2b9f80d5ae4f0c8413dcfd7ba70a40 185 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.9E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 2.4E-16 T 28-03-2018 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 SUPERFAMILY SSF48371 296 372 5.32E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 342 2.7E-119 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 3.3E-15 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 SMART SM00567 E-Z type HEAT repeats 330 359 3.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 SMART SM00567 E-Z type HEAT repeats 298 327 25.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Gene3D G3DSA:3.30.70.20 192 242 9.4E-8 T 28-03-2018 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Gene3D G3DSA:3.30.70.20 29 191 7.3E-5 T 28-03-2018 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Gene3D G3DSA:3.30.70.20 243 309 0.19 T 28-03-2018 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Gene3D G3DSA:1.25.40.290 310 380 9.6E-5 T 28-03-2018 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 Pfam PF13646 HEAT repeats 300 366 4.6E-9 T 28-03-2018 CPF12_RS02935 acd4e768ba3bd5438e1410c7fbc695a6 382 SUPERFAMILY SSF54862 164 261 4.18E-13 T 28-03-2018 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 Gene3D G3DSA:3.40.640.10 3 246 6.8E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 PIRSF PIRSF001434 2 365 7.7E-125 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 362 8.7E-128 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 Gene3D G3DSA:3.90.1150.10 279 365 2.3E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 Gene3D G3DSA:3.90.1150.10 248 278 2.6E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS03595 3c94f87af377f8475fcd7ea50038c765 367 SUPERFAMILY SSF53383 21 362 1.46E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Gene3D G3DSA:3.60.20.10 2 239 3.8E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Pfam PF01380 SIS domain 289 414 9.4E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Pfam PF01380 SIS domain 462 583 2.5E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Gene3D G3DSA:3.40.50.10490 453 599 5.0E-42 T 28-03-2018 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 SUPERFAMILY SSF53697 245 601 7.3E-91 T 28-03-2018 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 601 37.118 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 SUPERFAMILY SSF56235 2 223 5.06E-59 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 601 4.5E-215 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Pfam PF13522 Glutamine amidotransferase domain 63 191 9.1E-24 T 28-03-2018 CPF12_RS03160 305c89a458b8d8c8056f7f93e6b7bd8b 601 Gene3D G3DSA:3.40.50.10490 240 452 1.1E-53 T 28-03-2018 CPF12_RS09990 0f13f52ca767a0ee45b09b20cd944907 149 SUPERFAMILY SSF46785 14 143 7.61E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09990 0f13f52ca767a0ee45b09b20cd944907 149 Gene3D G3DSA:1.10.10.10 1 94 3.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS09990 0f13f52ca767a0ee45b09b20cd944907 149 Pfam PF01475 Ferric uptake regulator family 22 139 1.2E-38 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CPF12_RS05280 032b12a8e92e44635f92dcb51e49491e 68 SUPERFAMILY SSF47413 1 67 8.73E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05280 032b12a8e92e44635f92dcb51e49491e 68 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 67 3.8E-20 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05280 032b12a8e92e44635f92dcb51e49491e 68 SMART SM00530 6 62 6.2E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05280 032b12a8e92e44635f92dcb51e49491e 68 Gene3D G3DSA:1.10.260.40 1 68 1.4E-11 T 28-03-2018 CPF12_RS09100 df1216ada454da0b7d4acba85ebd8c6e 424 Pfam PF00860 Permease family 13 381 8.0E-31 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CPF12_RS07415 c62cc0ff0e2cb60596640090bb1d50c4 496 Gene3D G3DSA:1.10.10.10 90 158 0.012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07415 c62cc0ff0e2cb60596640090bb1d50c4 496 Gene3D G3DSA:1.10.10.10 5 65 0.31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07415 c62cc0ff0e2cb60596640090bb1d50c4 496 Pfam PF05043 Mga helix-turn-helix domain 81 166 3.9E-18 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 SUPERFAMILY SSF46894 128 224 1.81E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 SMART SM00862 149 224 2.6E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 Gene3D G3DSA:3.40.50.2300 1 125 6.6E-28 T 28-03-2018 CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 4.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 Pfam PF00072 Response regulator receiver domain 4 113 5.8E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 Gene3D G3DSA:1.10.10.10 126 225 7.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 SUPERFAMILY SSF52172 2 127 1.12E-33 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS08975 9f2b21449a7e88526df6344e11031873 225 SMART SM00448 2 112 1.8E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS09615 95c88b96a7bf3f73f3dddc77f9a07457 380 Pfam PF00266 Aminotransferase class-V 5 366 3.3E-74 T 28-03-2018 IPR000192 Aminotransferase class V domain CPF12_RS09615 95c88b96a7bf3f73f3dddc77f9a07457 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CPF12_RS09615 95c88b96a7bf3f73f3dddc77f9a07457 380 SUPERFAMILY SSF53383 3 374 2.17E-90 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS09615 95c88b96a7bf3f73f3dddc77f9a07457 380 Gene3D G3DSA:3.40.640.10 12 256 7.9E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS09615 95c88b96a7bf3f73f3dddc77f9a07457 380 PIRSF PIRSF005572 1 380 8.1E-115 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CPF12_RS09615 95c88b96a7bf3f73f3dddc77f9a07457 380 Gene3D G3DSA:3.90.1150.10 264 380 1.2E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS07095 804e02081d43f2730ac93529e0afb347 140 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 8 131 1.4E-29 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CPF12_RS11120 c43f9cefd01ec1703d2acd9d7ec3c4ba 286 Pfam PF07242 Protein of unknown function (DUF1430) 187 283 3.0E-10 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CPF12_RS12455 38f846145e48f02695c0a8111dbf7c99 236 Pfam PF02602 Uroporphyrinogen-III synthase HemD 16 225 8.2E-38 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12455 38f846145e48f02695c0a8111dbf7c99 236 Gene3D G3DSA:3.40.50.10090 120 232 2.5E-12 T 28-03-2018 CPF12_RS12455 38f846145e48f02695c0a8111dbf7c99 236 SUPERFAMILY SSF69618 1 229 2.62E-42 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CPF12_RS12455 38f846145e48f02695c0a8111dbf7c99 236 Gene3D G3DSA:3.40.50.10090 1 119 1.1E-23 T 28-03-2018 CPF12_RS03940 aad626ba5cf4e8053e40ba5f08c2555b 171 Pfam PF03551 Transcriptional regulator PadR-like family 12 84 2.8E-13 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CPF12_RS03940 aad626ba5cf4e8053e40ba5f08c2555b 171 Gene3D G3DSA:1.10.10.10 2 95 8.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03940 aad626ba5cf4e8053e40ba5f08c2555b 171 SUPERFAMILY SSF46785 10 167 3.08E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01225 582e20b10ef02fc5a4b6f0978162c296 160 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 4 76 1.1E-19 T 28-03-2018 IPR006343 DnaD domain CPF12_RS01225 582e20b10ef02fc5a4b6f0978162c296 160 SUPERFAMILY SSF158499 5 72 1.7E-12 T 28-03-2018 IPR006343 DnaD domain CPF12_RS01225 582e20b10ef02fc5a4b6f0978162c296 160 Pfam PF07261 Replication initiation and membrane attachment 6 76 2.0E-13 T 28-03-2018 IPR006343 DnaD domain CPF12_RS01225 582e20b10ef02fc5a4b6f0978162c296 160 Gene3D G3DSA:1.10.10.630 1 77 1.8E-17 T 28-03-2018 IPR034829 DnaD-like domain CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 SMART SM01130 2 290 2.8E-123 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 SUPERFAMILY SSF51569 2 287 1.99E-96 T 28-03-2018 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 Gene3D G3DSA:3.20.20.70 1 294 4.4E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 60.064 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 Pfam PF00701 Dihydrodipicolinate synthetase family 2 287 2.8E-99 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 7.1E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 7.1E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 7.1E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 7.1E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 PIRSF PIRSF001365 1 294 3.8E-89 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CPF12_RS12120 6010d41dcebf0b24244c96f0655fa0fa 294 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 287 3.0E-98 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS01300 40bafaa2989568e2a53a333b28e1506f 461 Gene3D G3DSA:1.20.120.20 14 136 4.1E-4 T 28-03-2018 CPF12_RS01300 40bafaa2989568e2a53a333b28e1506f 461 Gene3D G3DSA:1.10.287.700 215 320 1.6E-7 T 28-03-2018 CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 ProSitePatterns PS00211 ABC transporters family signature. 390 404 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 SMART SM00382 288 466 1.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 SMART SM00382 28 218 1.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 Gene3D G3DSA:3.40.50.300 258 474 1.9E-46 T 28-03-2018 CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 Gene3D G3DSA:3.40.50.300 1 257 2.8E-55 T 28-03-2018 CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 Pfam PF00005 ABC transporter 284 418 9.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 Pfam PF00005 ABC transporter 20 169 4.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 SUPERFAMILY SSF52540 1 225 3.17E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02705 7c14780ada81e79b3594fdb0d8c7b901 483 SUPERFAMILY SSF52540 260 472 2.8E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 Gene3D G3DSA:1.20.1260.10 2 159 8.2E-43 T 28-03-2018 IPR012347 Ferritin-related CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 PIRSF PIRSF005900 1 155 2.1E-45 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 128 146 1.3E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 55 71 1.3E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 31 47 1.3E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 SUPERFAMILY SSF47240 8 154 1.95E-48 T 28-03-2018 IPR009078 Ferritin-like superfamily CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 ProSitePatterns PS00818 Dps protein family signature 1. 31 47 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 Pfam PF00210 Ferritin-like domain 12 152 4.0E-26 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CPF12_RS08170 1fc14b7abdbde8ee194b9431cf3f507a 159 ProSitePatterns PS00819 Dps protein family signature 2. 57 71 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CPF12_RS09350 d897e6f950d80aa91897a282bdb84ed4 96 Gene3D G3DSA:1.10.3830.10 1 88 2.1E-30 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CPF12_RS09350 d897e6f950d80aa91897a282bdb84ed4 96 Pfam PF01219 Prokaryotic diacylglycerol kinase 1 86 5.0E-28 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CPF12_RS03135 75685f3affc0badc12645886258ff0a5 130 Gene3D G3DSA:1.10.10.10 1 130 1.3E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03135 75685f3affc0badc12645886258ff0a5 130 SUPERFAMILY SSF46785 2 128 9.84E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03135 75685f3affc0badc12645886258ff0a5 130 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 125 4.5E-34 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS03135 75685f3affc0badc12645886258ff0a5 130 Pfam PF02082 Transcriptional regulator 1 83 1.1E-24 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS03135 75685f3affc0badc12645886258ff0a5 130 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 ProSitePatterns PS00737 Thiolases signature 2. 295 311 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 Pfam PF00108 Thiolase, N-terminal domain 4 129 2.4E-19 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 Gene3D G3DSA:3.40.47.10 233 351 7.2E-17 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 PIRSF PIRSF000429 1 351 2.7E-59 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 Gene3D G3DSA:3.40.47.10 1 232 3.3E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 Pfam PF02803 Thiolase, C-terminal domain 227 348 3.0E-21 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 SUPERFAMILY SSF53901 188 349 2.17E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS08785 149fb748a87e5122402ba0f73402e63b 351 SUPERFAMILY SSF53901 34 115 2.17E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CPF12_RS07680 5fccbfb404cd67cb09808021c27a12fd 274 Gene3D G3DSA:3.40.190.10 33 133 4.2E-18 T 28-03-2018 CPF12_RS07680 5fccbfb404cd67cb09808021c27a12fd 274 SUPERFAMILY SSF53850 37 274 3.63E-62 T 28-03-2018 CPF12_RS07680 5fccbfb404cd67cb09808021c27a12fd 274 Pfam PF03180 NLPA lipoprotein 37 274 3.9E-63 T 28-03-2018 IPR004872 Lipoprotein NlpA family CPF12_RS07680 5fccbfb404cd67cb09808021c27a12fd 274 Gene3D G3DSA:3.40.190.10 134 274 1.1E-36 T 28-03-2018 CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 Gene3D G3DSA:3.90.1310.10 28 311 3.5E-34 T 28-03-2018 CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 297 3.0E-35 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 Gene3D G3DSA:3.40.710.10 312 698 8.3E-71 T 28-03-2018 CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 Pfam PF00905 Penicillin binding protein transpeptidase domain 344 680 3.7E-61 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 SUPERFAMILY SSF56601 312 687 1.36E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 SUPERFAMILY SSF56519 180 311 1.11E-32 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS01745 fb0ef7312b7e3652aa6a7f00fc47c2eb 708 SUPERFAMILY SSF56519 55 117 1.11E-32 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CPF12_RS01390 1eadd9e9e94c26c00c048c3063cfeaff 140 Gene3D G3DSA:1.10.287.100 106 139 4.2E-4 T 28-03-2018 CPF12_RS01390 1eadd9e9e94c26c00c048c3063cfeaff 140 SMART SM00347 24 124 8.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS01390 1eadd9e9e94c26c00c048c3063cfeaff 140 SUPERFAMILY SSF46785 6 138 3.52E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01390 1eadd9e9e94c26c00c048c3063cfeaff 140 Pfam PF01047 MarR family 31 88 7.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS01390 1eadd9e9e94c26c00c048c3063cfeaff 140 Gene3D G3DSA:1.10.10.10 20 105 1.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 SUPERFAMILY SSF52540 7 148 1.17E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 Gene3D G3DSA:1.10.287.890 198 277 2.4E-27 T 28-03-2018 CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 Gene3D G3DSA:3.40.50.300 2 193 8.0E-59 T 28-03-2018 CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 300 28.926 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 289 1.7E-95 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 SUPERFAMILY SSF52540 187 272 3.0E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 SUPERFAMILY SSF52540 5 70 3.0E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11855 b9912d2e182dc86ab09af8c523b58d93 310 Pfam PF01715 IPP transferase 39 280 1.2E-79 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 2.5E-89 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 SMART SM01133 2 214 1.1E-103 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 Pfam PF01791 DeoC/LacD family aldolase 7 208 1.8E-21 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 PIRSF PIRSF001357 1 220 3.9E-78 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 SUPERFAMILY SSF51569 1 213 8.27E-83 T 28-03-2018 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 Gene3D G3DSA:3.20.20.70 1 219 2.2E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS10310 5dea8bbfd99b51d00fd31e11a9b712ac 221 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.408 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CPF12_RS05135 b5a34870f37fe5088bbdaf117ff8f336 319 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 319 179.569 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CPF12_RS05135 b5a34870f37fe5088bbdaf117ff8f336 319 SMART SM01133 19 278 9.4E-29 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS05135 b5a34870f37fe5088bbdaf117ff8f336 319 SUPERFAMILY SSF51569 5 315 2.86E-62 T 28-03-2018 CPF12_RS05135 b5a34870f37fe5088bbdaf117ff8f336 319 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 2 316 3.2E-136 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CPF12_RS05135 b5a34870f37fe5088bbdaf117ff8f336 319 Pfam PF01791 DeoC/LacD family aldolase 21 277 1.2E-61 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CPF12_RS05135 b5a34870f37fe5088bbdaf117ff8f336 319 Gene3D G3DSA:3.20.20.70 2 319 3.2E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS05715 95fa3b504e0a192741e81224cba7dedd 325 SUPERFAMILY SSF50685 266 311 3.49E-7 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CPF12_RS05715 95fa3b504e0a192741e81224cba7dedd 325 Pfam PF06725 3D domain 264 325 4.8E-18 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CPF12_RS05715 95fa3b504e0a192741e81224cba7dedd 325 Pfam PF07501 G5 domain 121 194 9.0E-18 T 28-03-2018 IPR011098 G5 domain CPF12_RS05715 95fa3b504e0a192741e81224cba7dedd 325 Gene3D G3DSA:2.40.40.10 115 321 1.1E-37 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CPF12_RS05715 95fa3b504e0a192741e81224cba7dedd 325 SMART SM01208 117 195 1.1E-19 T 28-03-2018 IPR011098 G5 domain CPF12_RS09835 6456e64e3ace2bdba4af86654659309f 312 SUPERFAMILY SSF143865 120 233 2.22E-7 T 28-03-2018 CPF12_RS09835 6456e64e3ace2bdba4af86654659309f 312 SUPERFAMILY SSF144083 241 303 4.84E-12 T 28-03-2018 CPF12_RS09835 6456e64e3ace2bdba4af86654659309f 312 Pfam PF01544 CorA-like Mg2+ transporter protein 115 301 3.8E-27 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CPF12_RS09835 6456e64e3ace2bdba4af86654659309f 312 Gene3D G3DSA:1.20.58.340 126 237 1.2E-7 T 28-03-2018 CPF12_RS09835 6456e64e3ace2bdba4af86654659309f 312 Gene3D G3DSA:1.20.58.340 238 305 2.1E-12 T 28-03-2018 CPF12_RS03385 48d3538048a1fbaa07aa5476b89c6c13 349 Gene3D G3DSA:2.130.10.10 2 349 7.5E-40 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CPF12_RS03385 48d3538048a1fbaa07aa5476b89c6c13 349 SUPERFAMILY SSF51004 25 346 7.59E-41 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CPF12_RS03385 48d3538048a1fbaa07aa5476b89c6c13 349 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 344 2.5E-111 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.083 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 Gene3D G3DSA:3.10.430.100 60 147 8.5E-29 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 SUPERFAMILY SSF55653 58 147 9.29E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 6.0E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.1E-42 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 145 2.5E-27 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 SUPERFAMILY SSF55658 1 54 5.58E-16 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 Gene3D G3DSA:3.40.5.10 1 49 6.6E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05355 896b2b3df477c479ffd197a5cc756b8b 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS11370 868ba7277f9913d80fabf49c9d33e36f 202 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11370 868ba7277f9913d80fabf49c9d33e36f 202 Pfam PF00005 ABC transporter 20 158 5.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11370 868ba7277f9913d80fabf49c9d33e36f 202 SMART SM00382 26 201 3.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11370 868ba7277f9913d80fabf49c9d33e36f 202 Gene3D G3DSA:3.40.50.300 1 202 1.8E-52 T 28-03-2018 CPF12_RS11370 868ba7277f9913d80fabf49c9d33e36f 202 SUPERFAMILY SSF52540 2 202 1.42E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 SUPERFAMILY SSF53748 1 392 2.36E-159 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 Gene3D G3DSA:3.40.50.1260 3 178 1.3E-73 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 392 42.676 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 Gene3D G3DSA:3.40.50.1260 179 380 2.4E-85 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 345 356 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 368 385 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.9E-97 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 PIRSF PIRSF000724 1 393 6.5E-157 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS06905 0d0f8d8b4be9b7a18d9f172190511adc 393 Pfam PF00162 Phosphoglycerate kinase 6 382 2.2E-160 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CPF12_RS12420 c182ff6b297a511f1aece4d72926e9f7 414 Gene3D G3DSA:1.20.1250.20 1 198 1.9E-21 T 28-03-2018 CPF12_RS12420 c182ff6b297a511f1aece4d72926e9f7 414 Pfam PF07690 Major Facilitator Superfamily 13 364 3.8E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS12420 c182ff6b297a511f1aece4d72926e9f7 414 Gene3D G3DSA:1.20.1250.20 204 412 9.2E-15 T 28-03-2018 CPF12_RS12420 c182ff6b297a511f1aece4d72926e9f7 414 SUPERFAMILY SSF103473 10 404 4.71E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05315 fbe4a855cf14d3e14a96f1d4d6ebf27f 327 Pfam PF07751 Abi-like protein 54 225 3.9E-23 T 28-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like CPF12_RS05085 2c635a81863c45804843406cf080815b 358 Gene3D G3DSA:3.30.230.10 1 213 1.1E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CPF12_RS05085 2c635a81863c45804843406cf080815b 358 Pfam PF00288 GHMP kinases N terminal domain 111 168 6.9E-15 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CPF12_RS05085 2c635a81863c45804843406cf080815b 358 SUPERFAMILY SSF54211 5 224 2.35E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CPF12_RS05085 2c635a81863c45804843406cf080815b 358 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 7 347 6.0E-98 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 CPF12_RS05085 2c635a81863c45804843406cf080815b 358 Gene3D G3DSA:3.30.70.890 214 346 6.3E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05085 2c635a81863c45804843406cf080815b 358 SUPERFAMILY SSF55060 208 347 2.28E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS05085 2c635a81863c45804843406cf080815b 358 PRINTS PR00959 Mevalonate kinase family signature 8 32 6.1E-7 T 28-03-2018 CPF12_RS05085 2c635a81863c45804843406cf080815b 358 PRINTS PR00959 Mevalonate kinase family signature 307 324 6.1E-7 T 28-03-2018 CPF12_RS05085 2c635a81863c45804843406cf080815b 358 PRINTS PR00959 Mevalonate kinase family signature 106 128 6.1E-7 T 28-03-2018 CPF12_RS05085 2c635a81863c45804843406cf080815b 358 Pfam PF08544 GHMP kinases C terminal 261 328 2.0E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CPF12_RS06825 a47c7e4008fe8f08b56e315e0f679e97 252 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 239 3.8E-38 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CPF12_RS06825 a47c7e4008fe8f08b56e315e0f679e97 252 Gene3D G3DSA:3.20.20.190 1 244 3.3E-59 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS06825 a47c7e4008fe8f08b56e315e0f679e97 252 SUPERFAMILY SSF51695 3 239 5.23E-58 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CPF12_RS07930 880c4699cc5d9b2fdc3ab4cbb553d7e8 267 Gene3D G3DSA:3.90.190.10 28 209 4.3E-20 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CPF12_RS07930 880c4699cc5d9b2fdc3ab4cbb553d7e8 267 Pfam PF13350 Tyrosine phosphatase family 14 266 2.6E-55 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CPF12_RS07930 880c4699cc5d9b2fdc3ab4cbb553d7e8 267 SUPERFAMILY SSF52799 14 266 6.26E-45 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CPF12_RS10420 ab8b0b83f8377f218205ab535646fb99 183 SUPERFAMILY SSF102405 3 176 2.47E-62 T 28-03-2018 CPF12_RS10420 ab8b0b83f8377f218205ab535646fb99 183 Pfam PF06908 Protein of unknown function (DUF1273) 5 172 3.8E-70 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CPF12_RS10420 ab8b0b83f8377f218205ab535646fb99 183 PIRSF PIRSF021290 2 179 6.5E-70 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CPF12_RS10420 ab8b0b83f8377f218205ab535646fb99 183 Gene3D G3DSA:3.40.50.450 1 181 6.1E-33 T 28-03-2018 CPF12_RS10420 ab8b0b83f8377f218205ab535646fb99 183 Hamap MF_01575 UPF0398 protein . 2 178 35.487 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CPF12_RS07715 0cb662d8fd91181d04efdb9b586909cb 285 PIRSF PIRSF018249 4 285 6.9E-76 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 CPF12_RS07715 0cb662d8fd91181d04efdb9b586909cb 285 Gene3D G3DSA:3.40.50.150 16 285 8.4E-31 T 28-03-2018 CPF12_RS07715 0cb662d8fd91181d04efdb9b586909cb 285 SUPERFAMILY SSF53335 34 266 7.94E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS07715 0cb662d8fd91181d04efdb9b586909cb 285 Pfam PF13649 Methyltransferase domain 101 170 1.8E-7 T 28-03-2018 CPF12_RS02145 b5597d73f44764ebaee68588033feed3 205 SUPERFAMILY SSF142913 2 203 1.36E-71 T 28-03-2018 CPF12_RS02145 b5597d73f44764ebaee68588033feed3 205 Hamap MF_01851 UPF0637 protein . 5 201 36.596 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CPF12_RS02145 b5597d73f44764ebaee68588033feed3 205 PIRSF PIRSF021332 1 205 1.3E-81 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CPF12_RS02145 b5597d73f44764ebaee68588033feed3 205 Pfam PF06335 Protein of unknown function (DUF1054) 6 199 4.3E-72 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CPF12_RS05210 25792d90881dbbe89406766e831ec52d 378 Pfam PF00999 Sodium/hydrogen exchanger family 7 369 4.6E-75 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CPF12_RS05210 25792d90881dbbe89406766e831ec52d 378 Gene3D G3DSA:1.20.91.10 222 305 6.2E-17 T 28-03-2018 CPF12_RS10610 3b51a101504845031d7ba78b4dc6b3d7 177 Gene3D G3DSA:3.30.1060.10 1 174 1.2E-67 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10610 3b51a101504845031d7ba78b4dc6b3d7 177 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 165 36.389 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10610 3b51a101504845031d7ba78b4dc6b3d7 177 SUPERFAMILY SSF55068 3 167 3.4E-72 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10610 3b51a101504845031d7ba78b4dc6b3d7 177 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 158 6.7E-64 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10610 3b51a101504845031d7ba78b4dc6b3d7 177 Pfam PF01625 Peptide methionine sulfoxide reductase 9 159 6.0E-61 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS02290 dbf8d76be08c3fd6971acf1337631235 151 Gene3D G3DSA:3.40.50.300 1 149 1.3E-47 T 28-03-2018 CPF12_RS02290 dbf8d76be08c3fd6971acf1337631235 151 SUPERFAMILY SSF52540 19 123 4.66E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02290 dbf8d76be08c3fd6971acf1337631235 151 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 9 135 1.7E-35 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CPF12_RS02290 dbf8d76be08c3fd6971acf1337631235 151 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 125 3.0E-36 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 PRINTS PR00094 Adenylate kinase signature 4 17 5.1E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 PRINTS PR00094 Adenylate kinase signature 177 191 5.1E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 PRINTS PR00094 Adenylate kinase signature 160 175 5.1E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 PRINTS PR00094 Adenylate kinase signature 32 46 5.1E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 PRINTS PR00094 Adenylate kinase signature 81 97 5.1E-33 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 Pfam PF05191 Adenylate kinase, active site lid 127 162 4.7E-17 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 SUPERFAMILY SSF52540 1 213 3.38E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 Gene3D G3DSA:3.40.50.300 1 214 3.4E-64 T 28-03-2018 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 Pfam PF00406 Adenylate kinase 5 189 9.6E-60 T 28-03-2018 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 Hamap MF_00235 Adenylate kinase [adk]. 1 213 51.982 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CPF12_RS06165 6e9b5b906d593046f91911cb269c651d 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 6.5E-81 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CPF12_RS01320 3ca24583daafa57e1f508ab345bf0eb9 163 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 21 160 2.3E-18 T 28-03-2018 IPR006524 Transcription activator, ArpU family CPF12_RS03975 764a169c99ec56992ad71275cadb5c6f 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 50 219 1.8E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS03975 764a169c99ec56992ad71275cadb5c6f 220 SUPERFAMILY SSF161098 10 204 5.89E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS03975 764a169c99ec56992ad71275cadb5c6f 220 Gene3D G3DSA:1.10.3720.10 6 220 2.9E-36 T 28-03-2018 CPF12_RS04015 69eb6c5cf9a899494cc9cd3074ab91bc 281 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 11 280 8.1E-113 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CPF12_RS04015 69eb6c5cf9a899494cc9cd3074ab91bc 281 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 10 280 1.9E-134 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CPF12_RS11005 7c11189da726295e4c666fd11c9b35b5 276 Gene3D G3DSA:3.20.20.150 1 276 1.9E-57 T 28-03-2018 CPF12_RS11005 7c11189da726295e4c666fd11c9b35b5 276 Pfam PF01261 Xylose isomerase-like TIM barrel 21 225 4.8E-29 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS11005 7c11189da726295e4c666fd11c9b35b5 276 SUPERFAMILY SSF51658 4 273 1.93E-65 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS06880 e8e8d3c093695f9e683a0e9959179465 381 Gene3D G3DSA:2.120.10.60 26 324 0.0019 T 28-03-2018 CPF12_RS01470 f148bd87e04328c23275a38851048f02 283 Pfam PF01063 Amino-transferase class IV 29 251 8.9E-45 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CPF12_RS01470 f148bd87e04328c23275a38851048f02 283 Gene3D G3DSA:3.20.10.10 119 280 6.1E-38 T 28-03-2018 CPF12_RS01470 f148bd87e04328c23275a38851048f02 283 SUPERFAMILY SSF56752 1 272 2.75E-73 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CPF12_RS01470 f148bd87e04328c23275a38851048f02 283 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 2 276 5.0E-112 T 28-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CPF12_RS01470 f148bd87e04328c23275a38851048f02 283 Gene3D G3DSA:3.30.470.10 1 115 1.8E-25 T 28-03-2018 CPF12_RS05420 bee9da84fe0d03df8591968d1e3c863b 318 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 90 231 4.2E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CPF12_RS05420 bee9da84fe0d03df8591968d1e3c863b 318 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 89 231 5.1E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CPF12_RS07675 c281135a4aca810cef7b276f8d00185b 225 SUPERFAMILY SSF161098 13 207 3.71E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07675 c281135a4aca810cef7b276f8d00185b 225 Gene3D G3DSA:1.10.3720.10 9 223 3.6E-27 T 28-03-2018 CPF12_RS07675 c281135a4aca810cef7b276f8d00185b 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 60 224 3.8E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS02085 7d36d4f08c00dd5fe19363214420905d 184 SUPERFAMILY SSF53335 1 181 2.21E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS02085 7d36d4f08c00dd5fe19363214420905d 184 PIRSF PIRSF004553 1 184 1.2E-48 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CPF12_RS02085 7d36d4f08c00dd5fe19363214420905d 184 Gene3D G3DSA:3.40.50.150 1 183 4.6E-30 T 28-03-2018 CPF12_RS02085 7d36d4f08c00dd5fe19363214420905d 184 Pfam PF03602 Conserved hypothetical protein 95 1 181 3.1E-53 T 28-03-2018 CPF12_RS02085 7d36d4f08c00dd5fe19363214420905d 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 1.4E-51 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CPF12_RS02085 7d36d4f08c00dd5fe19363214420905d 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 Pfam PF01678 Diaminopimelate epimerase 161 269 1.3E-13 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 Pfam PF01678 Diaminopimelate epimerase 7 109 2.1E-19 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 SUPERFAMILY SSF54506 3 138 2.23E-25 T 28-03-2018 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 69 83 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 Gene3D G3DSA:3.10.310.10 1 131 8.1E-31 T 28-03-2018 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 288 29.557 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 6 286 3.6E-55 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 Gene3D G3DSA:3.10.310.10 132 272 1.1E-29 T 28-03-2018 CPF12_RS01965 d8ea8c794b3398bef2fe673dee1c6fc2 326 SUPERFAMILY SSF54506 150 285 4.71E-30 T 28-03-2018 CPF12_RS02125 c918de2938f14d39d94b17ca1e4b1fce 92 SUPERFAMILY SSF140404 5 82 9.42E-33 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CPF12_RS02125 c918de2938f14d39d94b17ca1e4b1fce 92 Gene3D G3DSA:1.10.287.750 6 88 1.7E-38 T 28-03-2018 CPF12_RS02125 c918de2938f14d39d94b17ca1e4b1fce 92 Pfam PF07408 Protein of unknown function (DUF1507) 8 88 5.8E-38 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CPF12_RS02125 c918de2938f14d39d94b17ca1e4b1fce 92 Hamap MF_01560 UPF0358 protein . 1 91 23.846 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CPF12_RS10520 570b4f3deb407edbddd95263547160fd 124 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 31 119 4.0E-6 T 28-03-2018 CPF12_RS10520 570b4f3deb407edbddd95263547160fd 124 Pfam PF14184 Regulatory protein YrvL 9 121 2.1E-11 T 28-03-2018 IPR025912 Regulatory protein YrvL CPF12_RS09465 7764d7535fbb43c48083ffd7b2401fff 227 Gene3D G3DSA:3.40.50.300 1 224 1.3E-48 T 28-03-2018 CPF12_RS09465 7764d7535fbb43c48083ffd7b2401fff 227 Pfam PF02224 Cytidylate kinase 6 221 7.2E-76 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CPF12_RS09465 7764d7535fbb43c48083ffd7b2401fff 227 Hamap MF_00238 Cytidylate kinase [cmk]. 4 225 32.919 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CPF12_RS09465 7764d7535fbb43c48083ffd7b2401fff 227 SUPERFAMILY SSF52540 1 224 2.04E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09465 7764d7535fbb43c48083ffd7b2401fff 227 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 218 6.4E-80 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 10 343 47.906 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 SUPERFAMILY SSF55681 94 344 5.97E-83 T 28-03-2018 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 41 344 9.6E-114 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 Gene3D G3DSA:3.30.930.10 9 347 5.5E-94 T 28-03-2018 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 22 89 5.8E-25 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 Pfam PF01409 tRNA synthetases class II core domain (F) 94 343 1.7E-107 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CPF12_RS02370 deb6bd5451574d6d38b83c07d9e14596 347 SUPERFAMILY SSF46589 16 101 4.71E-20 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CPF12_RS06805 a54930b6a0849c05509ff111f60ca2fe 224 Gene3D G3DSA:3.40.30.10 91 215 1.3E-11 T 28-03-2018 CPF12_RS06805 a54930b6a0849c05509ff111f60ca2fe 224 SUPERFAMILY SSF52833 107 212 3.02E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS00205 b2a01135aed34fcf1a78c85778bd7410 454 Gene3D G3DSA:3.20.20.70 143 449 2.2E-154 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS00205 b2a01135aed34fcf1a78c85778bd7410 454 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 4.2E-214 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CPF12_RS00205 b2a01135aed34fcf1a78c85778bd7410 454 Gene3D G3DSA:2.30.170.30 1 53 6.6E-25 T 28-03-2018 CPF12_RS00205 b2a01135aed34fcf1a78c85778bd7410 454 PIRSF PIRSF018788 1 454 8.1E-242 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CPF12_RS00205 b2a01135aed34fcf1a78c85778bd7410 454 Gene3D G3DSA:1.10.220.70 56 140 3.0E-34 T 28-03-2018 CPF12_RS06755 9825f004e683ca94137567577d5dc4b2 392 Pfam PF13349 Putative adhesin 135 363 4.5E-16 T 28-03-2018 IPR025164 Putative adhesin CPF12_RS01460 039c869a5ada826600031f66a48e235c 212 SUPERFAMILY SSF53335 30 209 8.11E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS01460 039c869a5ada826600031f66a48e235c 212 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 29.103 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CPF12_RS01460 039c869a5ada826600031f66a48e235c 212 Gene3D G3DSA:3.40.50.150 1 211 2.1E-26 T 28-03-2018 CPF12_RS01460 039c869a5ada826600031f66a48e235c 212 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 210 1.1E-56 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CPF12_RS01460 039c869a5ada826600031f66a48e235c 212 Pfam PF02390 Putative methyltransferase 38 207 1.0E-46 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CPF12_RS02770 1c429e0b71313394409eb399a2cf2536 385 Pfam PF06271 RDD family 213 360 9.0E-15 T 28-03-2018 IPR010432 RDD CPF12_RS02770 1c429e0b71313394409eb399a2cf2536 385 Pfam PF04892 VanZ like family 48 189 8.3E-24 T 28-03-2018 IPR006976 VanZ-like CPF12_RS02770 1c429e0b71313394409eb399a2cf2536 385 PIRSF PIRSF031578 1 384 7.4E-121 T 28-03-2018 IPR021192 Uncharacterised conserved protein UCP031578, VanZ/RDD-type CPF12_RS02565 215cfd856184c93db210849b5835e761 241 Pfam PF00756 Putative esterase 16 233 1.3E-31 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CPF12_RS02565 215cfd856184c93db210849b5835e761 241 SUPERFAMILY SSF53474 11 237 1.46E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS02565 215cfd856184c93db210849b5835e761 241 Gene3D G3DSA:3.40.50.1820 2 239 3.1E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS01310 04d6876dfb40fb4765926e41b874f20b 115 Pfam PF12363 Phage tail assembly chaperone protein, TAC 2 106 1.8E-25 T 28-03-2018 IPR024410 Phage tail assembly chaperone protein, TAC CPF12_RS02250 d411e84f41163c7d93c41eb6e7a755f4 106 SUPERFAMILY SSF46785 2 100 4.21E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02250 d411e84f41163c7d93c41eb6e7a755f4 106 Pfam PF03551 Transcriptional regulator PadR-like family 14 78 4.9E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CPF12_RS02250 d411e84f41163c7d93c41eb6e7a755f4 106 Gene3D G3DSA:1.10.10.10 4 105 2.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03320 ea15c43bb08e7edc3f84ccc823fba2eb 276 Gene3D G3DSA:3.30.420.40 1 99 1.6E-14 T 28-03-2018 CPF12_RS03320 ea15c43bb08e7edc3f84ccc823fba2eb 276 Pfam PF00480 ROK family 5 270 2.7E-35 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS03320 ea15c43bb08e7edc3f84ccc823fba2eb 276 SUPERFAMILY SSF53067 8 274 1.78E-46 T 28-03-2018 CPF12_RS03320 ea15c43bb08e7edc3f84ccc823fba2eb 276 Gene3D G3DSA:3.30.420.40 100 275 1.8E-40 T 28-03-2018 CPF12_RS09985 cf877a66d1253dfe085ec49d67268f9f 187 Gene3D G3DSA:2.40.380.10 11 170 3.2E-29 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CPF12_RS09985 cf877a66d1253dfe085ec49d67268f9f 187 Pfam PF04167 Protein of unknown function (DUF402) 60 124 5.5E-17 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CPF12_RS09985 cf877a66d1253dfe085ec49d67268f9f 187 SUPERFAMILY SSF159234 4 170 1.83E-28 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CPF12_RS09985 cf877a66d1253dfe085ec49d67268f9f 187 PIRSF PIRSF028345 1 180 6.2E-72 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 Pfam PF03382 Mycoplasma protein of unknown function, DUF285 169 288 2.8E-16 T 28-03-2018 IPR005046 Protein of unknown function DUF285 CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 Gene3D G3DSA:2.60.40.10 422 507 0.019 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 Gene3D G3DSA:2.60.40.10 594 683 2.9E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 Pfam PF07523 Bacterial Ig-like domain (group 3) 602 671 3.4E-7 T 28-03-2018 IPR022038 Bacterial Ig-like domain CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 Pfam PF07523 Bacterial Ig-like domain (group 3) 432 499 2.0E-4 T 28-03-2018 IPR022038 Bacterial Ig-like domain CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 Gene3D G3DSA:3.80.10.10 22 396 9.3E-11 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CPF12_RS00685 a52c80073e1c1b7ef144ec45fda4de80 818 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 200 219 3.4E-4 T 28-03-2018 IPR011889 Bacterial surface protein 26-residue repeat CPF12_RS10850 18bc95cffdb1abe40ca5a0eb878257cb 246 Gene3D G3DSA:3.20.20.70 4 245 5.4E-116 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS10850 18bc95cffdb1abe40ca5a0eb878257cb 246 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 8 243 7.3E-122 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CPF12_RS10850 18bc95cffdb1abe40ca5a0eb878257cb 246 Pfam PF07071 KDGP aldolase 9 224 1.2E-108 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CPF12_RS08835 a6635885aa50d0085df6e50189c77343 208 SUPERFAMILY SSF46785 138 202 1.69E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08835 a6635885aa50d0085df6e50189c77343 208 Gene3D G3DSA:1.10.10.10 123 203 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 Gene3D G3DSA:3.40.50.2000 687 877 4.6E-22 T 28-03-2018 CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 SUPERFAMILY SSF53756 145 356 8.79E-7 T 28-03-2018 CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 Gene3D G3DSA:3.40.50.2000 194 535 0.3 T 28-03-2018 CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 SUPERFAMILY SSF53756 514 612 1.02E-28 T 28-03-2018 CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 SUPERFAMILY SSF53756 705 879 1.02E-28 T 28-03-2018 CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 27 380 4.3E-58 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CPF12_RS04255 335c2c2fdee60b6cc43ed58da115c0d4 891 Pfam PF00534 Glycosyl transferases group 1 717 859 4.0E-19 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 Gene3D G3DSA:3.30.70.260 138 218 6.5E-7 T 28-03-2018 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 SUPERFAMILY SSF143548 19 136 8.89E-25 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 Gene3D G3DSA:3.30.1330.90 13 137 1.1E-19 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 PIRSF PIRSF036692 1 222 1.3E-68 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 Pfam PF03315 Serine dehydratase beta chain 13 87 5.3E-12 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 3.5E-57 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CPF12_RS11225 295b4a3be1a38d79054fc918a35b0678 223 SUPERFAMILY SSF55021 140 209 8.74E-10 T 28-03-2018 CPF12_RS08515 8eb3e64dd2eb6f9cfab75ddcfd811282 379 SUPERFAMILY SSF56266 6 371 1.33E-93 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS08515 8eb3e64dd2eb6f9cfab75ddcfd811282 379 Pfam PF03576 Peptidase family S58 23 354 8.2E-99 T 28-03-2018 IPR005321 Peptidase S58, DmpA CPF12_RS08515 8eb3e64dd2eb6f9cfab75ddcfd811282 379 Gene3D G3DSA:3.60.70.12 6 372 4.1E-99 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CPF12_RS04805 3a9a9e558e68e3187c28a669d2c18a81 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 150 2.1E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04805 3a9a9e558e68e3187c28a669d2c18a81 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 4.6E-59 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04805 3a9a9e558e68e3187c28a669d2c18a81 154 Gene3D G3DSA:3.40.50.960 1 154 4.5E-68 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04805 3a9a9e558e68e3187c28a669d2c18a81 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 30.761 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04805 3a9a9e558e68e3187c28a669d2c18a81 154 SUPERFAMILY SSF52121 3 153 6.02E-64 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS11355 ab17aff9b710f593ef10f13f02dc2449 209 SUPERFAMILY SSF53271 9 208 3.8E-54 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS11355 ab17aff9b710f593ef10f13f02dc2449 209 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 209 31.224 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11355 ab17aff9b710f593ef10f13f02dc2449 209 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 9 178 7.2E-46 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CPF12_RS11355 ab17aff9b710f593ef10f13f02dc2449 209 Pfam PF00156 Phosphoribosyl transferase domain 47 152 1.4E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CPF12_RS11355 ab17aff9b710f593ef10f13f02dc2449 209 Gene3D G3DSA:3.40.50.2020 2 209 3.6E-44 T 28-03-2018 CPF12_RS08115 58ea4350c6bf13352b722a95fd1120fc 236 SUPERFAMILY SSF51069 8 233 3.27E-57 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CPF12_RS08115 58ea4350c6bf13352b722a95fd1120fc 236 Pfam PF00194 Eukaryotic-type carbonic anhydrase 8 234 1.6E-38 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CPF12_RS08115 58ea4350c6bf13352b722a95fd1120fc 236 Gene3D G3DSA:3.10.200.10 5 235 1.6E-54 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CPF12_RS08115 58ea4350c6bf13352b722a95fd1120fc 236 SMART SM01057 9 236 7.3E-52 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CPF12_RS08115 58ea4350c6bf13352b722a95fd1120fc 236 ProSitePatterns PS00162 Alpha-carbonic anhydrases signature. 104 120 - T 28-03-2018 IPR018338 Carbonic anhydrase, alpha-class, conserved site GO:0004089|GO:0006730|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117|Reactome: R-HSA-1475029 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 SUPERFAMILY SSF53335 20 257 3.38E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 2 278 1.1E-69 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 Gene3D G3DSA:3.40.50.150 80 280 9.8E-48 T 28-03-2018 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 183 189 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 Gene3D G3DSA:1.10.8.10 1 79 4.7E-14 T 28-03-2018 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 276 1.8E-85 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 280 40.71 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CPF12_RS06440 091161eaf6667d0b9e0109e2ce905e94 280 Pfam PF05175 Methyltransferase small domain 104 196 1.7E-17 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CPF12_RS06560 40da019e41f6b9d16e62169da045ab37 258 PIRSF PIRSF016557 1 255 1.1E-84 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CPF12_RS06560 40da019e41f6b9d16e62169da045ab37 258 Gene3D G3DSA:3.20.20.140 1 237 5.3E-20 T 28-03-2018 CPF12_RS06560 40da019e41f6b9d16e62169da045ab37 258 SUPERFAMILY SSF89550 1 199 2.55E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CPF12_RS03835 1780028cbcfd085dc8a0258e68b8a647 112 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 80 2.3E-22 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CPF12_RS03835 1780028cbcfd085dc8a0258e68b8a647 112 SUPERFAMILY SSF54909 1 107 2.11E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CPF12_RS03835 1780028cbcfd085dc8a0258e68b8a647 112 Gene3D G3DSA:3.30.70.100 1 110 1.2E-25 T 28-03-2018 CPF12_RS10815 3651447ee1b69a80b5c9625307095d93 110 SUPERFAMILY SSF63520 39 109 1.31E-7 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10815 3651447ee1b69a80b5c9625307095d93 110 Pfam PF00874 PRD domain 38 106 1.6E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS10815 3651447ee1b69a80b5c9625307095d93 110 TIGRFAM TIGR03582 EF_0829: PRD domain protein, EF_0829/AHA_3910 family 7 110 4.8E-33 T 28-03-2018 IPR020044 PRD domain protein, EF0829/AHA3910 CPF12_RS10815 3651447ee1b69a80b5c9625307095d93 110 Gene3D G3DSA:1.10.1790.10 5 110 4.3E-9 T 28-03-2018 IPR011608 PRD domain GO:0006355 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 SUPERFAMILY SSF55021 77 154 2.14E-11 T 28-03-2018 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 Pfam PF10369 Small subunit of acetolactate synthase 85 151 8.8E-12 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 SUPERFAMILY SSF55021 2 77 1.04E-10 T 28-03-2018 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 Gene3D G3DSA:3.30.70.1150 89 156 2.9E-14 T 28-03-2018 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 155 9.9E-28 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 Gene3D G3DSA:3.30.70.260 2 88 5.1E-15 T 28-03-2018 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 2.0E-13 T 28-03-2018 CPF12_RS01940 0b225204ebf9af66387bd5340485e788 156 Pfam PF13710 ACT domain 11 72 3.5E-7 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 Gene3D G3DSA:1.20.1250.20 16 207 2.1E-22 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 Pfam PF00854 POT family 94 459 1.0E-71 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 Gene3D G3DSA:1.20.1250.20 220 286 0.2 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 15 492 8.7E-130 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 SUPERFAMILY SSF103473 278 485 1.57E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 SUPERFAMILY SSF103473 18 224 1.57E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 Gene3D G3DSA:1.20.1250.20 287 490 1.6E-11 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 243 268 5.4E-5 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 190 208 5.4E-5 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 65 87 5.4E-5 T 28-03-2018 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 157 169 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CPF12_RS05670 952805cd0a1fff7f4f536e6aa3fbc4ac 496 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 82 106 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CPF12_RS06550 03d9eb542259da56f67597e646ad6078 234 Gene3D G3DSA:3.30.1890.10 33 172 3.0E-8 T 28-03-2018 CPF12_RS06550 03d9eb542259da56f67597e646ad6078 234 Pfam PF02706 Chain length determinant protein 4 91 4.5E-15 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CPF12_RS06550 03d9eb542259da56f67597e646ad6078 234 Pfam PF13807 G-rich domain on putative tyrosine kinase 140 193 1.2E-7 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 209 2.2E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 Gene3D G3DSA:1.10.3720.10 10 208 1.5E-30 T 28-03-2018 CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 Gene3D G3DSA:3.40.190.10 224 387 1.1E-33 T 28-03-2018 CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 234 499 1.0E-61 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 SUPERFAMILY SSF161098 13 197 1.2E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 Gene3D G3DSA:3.40.190.10 388 502 1.6E-25 T 28-03-2018 CPF12_RS00480 1ed9125820de2eb6b95b36b3d44c35d2 503 SUPERFAMILY SSF53850 234 501 2.65E-72 T 28-03-2018 CPF12_RS05370 acb8b50175b0bcdb6bde8c360386e025 277 Pfam PF10978 Protein of unknown function (DUF2785) 97 266 2.2E-20 T 28-03-2018 IPR021247 Protein of unknown function DUF2785 CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 SMART SM00862 145 220 1.1E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 SUPERFAMILY SSF52172 2 179 4.55E-40 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 SMART SM00448 1 112 8.0E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 1.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 Gene3D G3DSA:3.40.50.2300 1 120 2.9E-36 T 28-03-2018 CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 Pfam PF00072 Response regulator receiver domain 4 112 4.9E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS11910 5a40d95e3602dac648963019c169c702 229 Gene3D G3DSA:1.10.10.10 121 227 1.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10650 dd03a15071fce0540113d4d739f4ca28 560 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 8 558 1.0E-193 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CPF12_RS10650 dd03a15071fce0540113d4d739f4ca28 560 PIRSF PIRSF001294 1 560 9.3E-215 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CPF12_RS10650 dd03a15071fce0540113d4d739f4ca28 560 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 560 31.726 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CPF12_RS10650 dd03a15071fce0540113d4d739f4ca28 560 Pfam PF03814 Potassium-transporting ATPase A subunit 10 558 7.7E-218 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 SUPERFAMILY SSF63380 93 196 2.89E-26 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 196 9.6E-64 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 Pfam PF00677 Lumazine binding domain 3 86 2.7E-24 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 Pfam PF00677 Lumazine binding domain 100 184 4.7E-20 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 PIRSF PIRSF000498 1 209 1.7E-68 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 Gene3D G3DSA:2.40.30.20 94 191 5.0E-26 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 SUPERFAMILY SSF63380 1 88 1.11E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CPF12_RS04815 b962e23aacc37d47b1eabdb556394c3d 211 Gene3D G3DSA:2.40.30.20 1 89 2.7E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS03665 827803d644e2e1a312a7d8d1c281fc9a 554 SUPERFAMILY SSF81296 34 130 5.88E-19 T 28-03-2018 IPR014756 Immunoglobulin E-set CPF12_RS03665 827803d644e2e1a312a7d8d1c281fc9a 554 Pfam PF05425 Copper resistance protein D 343 436 3.5E-10 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CPF12_RS03665 827803d644e2e1a312a7d8d1c281fc9a 554 Pfam PF04234 CopC domain 35 129 4.7E-19 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CPF12_RS03665 827803d644e2e1a312a7d8d1c281fc9a 554 Gene3D G3DSA:2.60.40.1220 34 132 4.8E-22 T 28-03-2018 CPF12_RS12150 30cab14dc1cf585f19aced778cbc06e0 91 SUPERFAMILY SSF55729 5 89 2.7E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS12150 30cab14dc1cf585f19aced778cbc06e0 91 Pfam PF14542 GCN5-related N-acetyl-transferase 15 88 7.0E-26 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CPF12_RS12150 30cab14dc1cf585f19aced778cbc06e0 91 Gene3D G3DSA:3.40.630.30 4 91 5.2E-22 T 28-03-2018 CPF12_RS00355 0e992297fd77f0d38591a334aadd7124 106 Pfam PF00893 Small Multidrug Resistance protein 6 87 1.7E-14 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CPF12_RS00355 0e992297fd77f0d38591a334aadd7124 106 SUPERFAMILY SSF103481 8 103 9.94E-12 T 28-03-2018 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 4.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 4.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 4.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 4.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 4.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 4.3E-56 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 SUPERFAMILY SSF50249 2 136 2.48E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 1.1E-65 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 PIRSF PIRSF002133 1 137 1.1E-47 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.334 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 Pfam PF00164 Ribosomal protein S12/S23 32 136 8.3E-37 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06030 7ccca7703a5ab135b9be17093c272b6d 137 Gene3D G3DSA:2.40.50.140 1 137 2.4E-61 T 28-03-2018 CPF12_RS00285 567609d543ef2a6f32b8ab741bb5e974 567 Gene3D G3DSA:3.30.565.10 297 560 1.9E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00285 567609d543ef2a6f32b8ab741bb5e974 567 SUPERFAMILY SSF55874 420 560 9.43E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00285 567609d543ef2a6f32b8ab741bb5e974 567 Pfam PF06580 Histidine kinase 360 437 2.8E-23 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CPF12_RS09640 c511ba2e627fea8838e38544d5fdd599 140 Pfam PF02566 OsmC-like protein 40 135 4.4E-18 T 28-03-2018 IPR003718 OsmC/Ohr family CPF12_RS09640 c511ba2e627fea8838e38544d5fdd599 140 Gene3D G3DSA:3.30.300.20 45 140 1.9E-23 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CPF12_RS09640 c511ba2e627fea8838e38544d5fdd599 140 SUPERFAMILY SSF82784 1 137 2.62E-41 T 28-03-2018 IPR003718 OsmC/Ohr family CPF12_RS09640 c511ba2e627fea8838e38544d5fdd599 140 Gene3D G3DSA:2.20.25.10 1 44 1.1E-12 T 28-03-2018 CPF12_RS09640 c511ba2e627fea8838e38544d5fdd599 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 136 6.0E-52 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CPF12_RS01705 87670ae0b11630caff0d59cd25621ac1 132 SUPERFAMILY SSF102546 1 132 5.75E-41 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CPF12_RS01705 87670ae0b11630caff0d59cd25621ac1 132 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 132 29.941 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 CPF12_RS01705 87670ae0b11630caff0d59cd25621ac1 132 Pfam PF05025 RbsD / FucU transport protein family 1 130 4.2E-44 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CPF12_RS01705 87670ae0b11630caff0d59cd25621ac1 132 Gene3D G3DSA:3.40.1650.10 8 129 1.3E-36 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CPF12_RS03090 2f6671fc1ca25f4eaab0332ad2a62515 325 SUPERFAMILY SSF54593 2 302 1.93E-47 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03090 2f6671fc1ca25f4eaab0332ad2a62515 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 264 4.4E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS03090 2f6671fc1ca25f4eaab0332ad2a62515 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 124 1.9E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS03090 2f6671fc1ca25f4eaab0332ad2a62515 325 Gene3D G3DSA:3.10.180.10 2 147 4.5E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS03090 2f6671fc1ca25f4eaab0332ad2a62515 325 Gene3D G3DSA:3.10.180.10 150 318 6.3E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS11830 c5c47e3dbb4f8f8298f7af7c30dfc706 399 Pfam PF01263 Aldose 1-epimerase 112 376 2.5E-27 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CPF12_RS11830 c5c47e3dbb4f8f8298f7af7c30dfc706 399 SUPERFAMILY SSF74650 94 398 4.33E-51 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CPF12_RS11830 c5c47e3dbb4f8f8298f7af7c30dfc706 399 Gene3D G3DSA:2.70.98.10 110 399 4.1E-55 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CPF12_RS05520 f5a857332fcc63a9cbdee61fc7927a38 72 SUPERFAMILY SSF55174 3 63 5.21E-18 T 28-03-2018 CPF12_RS05520 f5a857332fcc63a9cbdee61fc7927a38 72 Pfam PF13275 S4 domain 4 68 3.3E-27 T 28-03-2018 CPF12_RS05520 f5a857332fcc63a9cbdee61fc7927a38 72 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 60 5.2E-31 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA CPF12_RS05520 f5a857332fcc63a9cbdee61fc7927a38 72 Gene3D G3DSA:3.10.290.10 1 69 2.3E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CPF12_RS12090 4111bba8a99278b9a50c3e69df45d903 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 106 2.4E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CPF12_RS12090 4111bba8a99278b9a50c3e69df45d903 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 1.3E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS12090 4111bba8a99278b9a50c3e69df45d903 215 SUPERFAMILY SSF161098 11 197 6.8E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS12090 4111bba8a99278b9a50c3e69df45d903 215 Gene3D G3DSA:1.10.3720.10 2 215 2.2E-51 T 28-03-2018 CPF12_RS06660 51d514847d14bd2fcee168779e7c58ab 228 SMART SM00382 27 221 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06660 51d514847d14bd2fcee168779e7c58ab 228 SUPERFAMILY SSF52540 1 218 1.82E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06660 51d514847d14bd2fcee168779e7c58ab 228 Pfam PF00005 ABC transporter 20 165 9.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS06660 51d514847d14bd2fcee168779e7c58ab 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06660 51d514847d14bd2fcee168779e7c58ab 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 7.6E-88 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CPF12_RS06660 51d514847d14bd2fcee168779e7c58ab 228 Gene3D G3DSA:3.40.50.300 1 225 8.0E-64 T 28-03-2018 CPF12_RS11240 0ee2562b277593df9d999cee21313307 543 PIRSF PIRSF038958 1 541 4.0E-112 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CPF12_RS11240 0ee2562b277593df9d999cee21313307 543 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 376 524 1.7E-30 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CPF12_RS11240 0ee2562b277593df9d999cee21313307 543 Pfam PF01943 Polysaccharide biosynthesis protein 5 322 7.7E-31 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CPF12_RS03540 6a94e0576c0f94f9775bcc81fb571400 243 Gene3D G3DSA:2.60.40.810 30 218 4.8E-5 T 28-03-2018 CPF12_RS03540 6a94e0576c0f94f9775bcc81fb571400 243 Pfam PF16555 Gram-positive pilin subunit D1, N-terminal 23 187 2.3E-10 T 28-03-2018 IPR032364 Gram-positive pilin subunit D1, N-terminal CPF12_RS03540 6a94e0576c0f94f9775bcc81fb571400 243 Pfam PF00746 LPXTG cell wall anchor motif 203 234 8.7E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS03540 6a94e0576c0f94f9775bcc81fb571400 243 SUPERFAMILY SSF49478 88 151 4.71E-5 T 28-03-2018 CPF12_RS03540 6a94e0576c0f94f9775bcc81fb571400 243 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 210 237 1.3E-5 T 28-03-2018 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 Gene3D G3DSA:3.20.20.70 19 272 1.9E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 52.341 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 294 1.5E-151 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 PIRSF PIRSF029271 1 295 1.4E-151 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 Pfam PF01680 SOR/SNZ family 8 213 4.6E-106 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS12000 12c408b66c6a3b5d941647176175fa22 295 SUPERFAMILY SSF51366 19 269 6.59E-69 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Gene3D G3DSA:1.25.40.10 102 133 1.3E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Pfam PF13414 TPR repeat 31 70 4.6E-8 T 28-03-2018 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Gene3D G3DSA:1.25.40.10 1 49 3.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 SMART SM00028 92 125 0.26 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 SMART SM00028 126 159 0.04 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 SMART SM00028 24 57 8.3E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 SMART SM00028 58 91 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 SUPERFAMILY SSF48452 2 196 6.45E-34 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Gene3D G3DSA:1.25.40.10 134 208 6.2E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Pfam PF13432 Tetratricopeptide repeat 96 150 1.8E-6 T 28-03-2018 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Gene3D G3DSA:1.20.58.280 50 78 4.4E-9 T 28-03-2018 CPF12_RS09625 35d3d85c3d367bb5389ad9ae9c580b14 209 Gene3D G3DSA:1.20.58.280 79 101 5.6E-4 T 28-03-2018 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 Pfam PF00232 Glycosyl hydrolase family 1 5 475 1.4E-132 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 Gene3D G3DSA:3.20.20.80 3 478 9.9E-151 T 28-03-2018 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 4.5E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 4.5E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 4.5E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 4.5E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 4.5E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 SUPERFAMILY SSF51445 3 471 9.97E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS00245 64d17daae020603422ffb9e07e4261ff 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS03460 7ab5ed32880047d1ef72d13ffd373680 35 Pfam PF13333 Integrase core domain 1 31 1.1E-5 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CPF12_RS01670 692ba8f5dd0479e3cadca8bb9d75894b 142 Pfam PF00085 Thioredoxin 47 139 1.3E-9 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CPF12_RS01670 692ba8f5dd0479e3cadca8bb9d75894b 142 SUPERFAMILY SSF52833 40 138 4.04E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS01670 692ba8f5dd0479e3cadca8bb9d75894b 142 Gene3D G3DSA:3.40.30.10 26 142 1.7E-19 T 28-03-2018 CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 PIRSF PIRSF001589 1 628 1.1E-196 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 Gene3D G3DSA:3.40.50.620 223 617 1.1E-82 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 SUPERFAMILY SSF52402 467 605 6.29E-86 T 28-03-2018 CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 SUPERFAMILY SSF52402 230 380 6.29E-86 T 28-03-2018 CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 SUPERFAMILY SSF56235 1 225 1.8E-59 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 Pfam PF13537 Glutamine amidotransferase domain 51 168 2.0E-43 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 3.4E-164 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 Pfam PF00733 Asparagine synthase 240 610 6.7E-111 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CPF12_RS11150 bb48a438bf6f70a8d79e4996da735d7b 633 Gene3D G3DSA:3.60.20.10 1 222 1.9E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS05550 f66bcbd7f96c1eb0220a77dbec9bcecd 204 Pfam PF00510 Cytochrome c oxidase subunit III 24 201 2.1E-17 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05550 f66bcbd7f96c1eb0220a77dbec9bcecd 204 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 13 202 2.1E-91 T 28-03-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 CPF12_RS05550 f66bcbd7f96c1eb0220a77dbec9bcecd 204 SUPERFAMILY SSF81452 19 201 4.06E-49 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS05550 f66bcbd7f96c1eb0220a77dbec9bcecd 204 Gene3D G3DSA:1.20.120.80 16 203 5.2E-48 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS08295 490ff1e1f35889bf25436209d662d934 89 Gene3D G3DSA:3.30.70.260 1 85 8.0E-19 T 28-03-2018 CPF12_RS08295 490ff1e1f35889bf25436209d662d934 89 SUPERFAMILY SSF55021 1 83 1.12E-16 T 28-03-2018 CPF12_RS08295 490ff1e1f35889bf25436209d662d934 89 Pfam PF13740 ACT domain 4 76 2.0E-11 T 28-03-2018 CPF12_RS08295 490ff1e1f35889bf25436209d662d934 89 Hamap MF_01054 UPF0237 protein . 1 89 24.008 T 28-03-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type CPF12_RS02605 ab3145f026435138db3cef385ed08a19 216 Gene3D G3DSA:3.30.460.10 1 145 1.1E-36 T 28-03-2018 CPF12_RS02605 ab3145f026435138db3cef385ed08a19 216 Gene3D G3DSA:1.10.287.860 147 195 4.6E-19 T 28-03-2018 CPF12_RS02605 ab3145f026435138db3cef385ed08a19 216 SUPERFAMILY SSF81301 3 200 7.19E-61 T 28-03-2018 CPF12_RS02605 ab3145f026435138db3cef385ed08a19 216 Pfam PF04607 Region found in RelA / SpoT proteins 43 162 1.1E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CPF12_RS02605 ab3145f026435138db3cef385ed08a19 216 SMART SM00954 43 164 1.4E-38 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 Gene3D G3DSA:1.20.120.570 437 598 2.9E-13 T 28-03-2018 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 Gene3D G3DSA:1.20.120.570 599 777 3.0E-14 T 28-03-2018 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 SUPERFAMILY SSF82866 828 1023 4.19E-25 T 28-03-2018 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 Gene3D G3DSA:1.20.1640.10 811 1027 5.1E-23 T 28-03-2018 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 Gene3D G3DSA:1.20.1640.10 113 338 1.2E-31 T 28-03-2018 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 SUPERFAMILY SSF82866 151 341 1.09E-31 T 28-03-2018 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 Pfam PF03176 MMPL family 744 1027 3.5E-32 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CPF12_RS04240 984935444b6d6a4d6b2f7e8da5316917 1037 Pfam PF03176 MMPL family 45 358 9.3E-58 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CPF12_RS00770 dc17bb3db9b72df0fb340ac212ea8217 343 SUPERFAMILY SSF51735 4 136 7.6E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00770 dc17bb3db9b72df0fb340ac212ea8217 343 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 6 105 2.3E-9 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CPF12_RS00770 dc17bb3db9b72df0fb340ac212ea8217 343 Gene3D G3DSA:3.40.50.720 1 132 2.3E-10 T 28-03-2018 CPF12_RS12010 cf734dc3f084dc6e46fc42b10581bed2 182 Gene3D G3DSA:3.40.50.850 1 182 1.9E-48 T 28-03-2018 CPF12_RS12010 cf734dc3f084dc6e46fc42b10581bed2 182 SUPERFAMILY SSF52499 2 181 1.7E-48 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CPF12_RS12010 cf734dc3f084dc6e46fc42b10581bed2 182 Pfam PF00857 Isochorismatase family 4 176 5.2E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CPF12_RS03310 d2b24e23bdf35c8e48bd706c0e877b6c 259 Gene3D G3DSA:3.40.630.30 65 234 2.3E-18 T 28-03-2018 CPF12_RS03310 d2b24e23bdf35c8e48bd706c0e877b6c 259 Gene3D G3DSA:3.30.420.40 4 64 6.7E-4 T 28-03-2018 CPF12_RS03310 d2b24e23bdf35c8e48bd706c0e877b6c 259 Pfam PF13302 Acetyltransferase (GNAT) domain 64 201 7.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS03310 d2b24e23bdf35c8e48bd706c0e877b6c 259 SUPERFAMILY SSF55729 54 226 1.51E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS02870 62fb46317dc904e5a35224e15111ab6d 305 Gene3D G3DSA:3.10.50.40 144 244 8.5E-16 T 28-03-2018 CPF12_RS02870 62fb46317dc904e5a35224e15111ab6d 305 Pfam PF13616 PPIC-type PPIASE domain 160 242 1.8E-11 T 28-03-2018 CPF12_RS02870 62fb46317dc904e5a35224e15111ab6d 305 SUPERFAMILY SSF109998 34 178 2.98E-15 T 28-03-2018 IPR027304 Trigger factor/SurA domain CPF12_RS02870 62fb46317dc904e5a35224e15111ab6d 305 SUPERFAMILY SSF54534 152 243 4.41E-13 T 28-03-2018 CPF12_RS02870 62fb46317dc904e5a35224e15111ab6d 305 Gene3D G3DSA:1.10.4030.10 29 134 3.3E-5 T 28-03-2018 CPF12_RS01975 77bff620ec2d4209211d0168331720ce 200 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 1.4E-16 T 28-03-2018 IPR019933 DivIVA domain CPF12_RS01975 77bff620ec2d4209211d0168331720ce 200 Pfam PF05103 DivIVA protein 3 133 4.8E-46 T 28-03-2018 IPR007793 DivIVA family CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Gene3D G3DSA:1.10.730.10 566 804 2.5E-60 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Pfam PF08264 Anticodon-binding domain of tRNA 657 766 9.4E-20 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Gene3D G3DSA:3.40.50.620 365 565 1.2E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 1.5E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Gene3D G3DSA:3.40.50.620 1 305 6.7E-94 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 804 22.496 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 804 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 SUPERFAMILY SSF50677 224 410 1.36E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 SUPERFAMILY SSF52374 411 624 6.47E-140 T 28-03-2018 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 SUPERFAMILY SSF52374 2 224 6.47E-140 T 28-03-2018 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 1.6E-66 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 SUPERFAMILY SSF47323 617 804 4.49E-38 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 602 6.7E-21 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS11210 cf4c178ef2203ec777a135fa7e950d7e 805 Pfam PF09334 tRNA synthetases class I (M) 39 170 5.2E-16 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CPF12_RS01690 954a8b55fa26352aed24ec41a5122732 305 Pfam PF13407 Periplasmic binding protein domain 39 289 8.0E-64 T 28-03-2018 IPR025997 Periplasmic binding protein CPF12_RS01690 954a8b55fa26352aed24ec41a5122732 305 SUPERFAMILY SSF53822 35 304 2.67E-85 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CPF12_RS01690 954a8b55fa26352aed24ec41a5122732 305 Gene3D G3DSA:3.40.50.2300 151 301 6.8E-41 T 28-03-2018 CPF12_RS01690 954a8b55fa26352aed24ec41a5122732 305 Gene3D G3DSA:3.40.50.2300 33 150 1.1E-30 T 28-03-2018 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 SUPERFAMILY SSF50129 1 94 1.41E-32 T 28-03-2018 IPR011032 GroES-like CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 26.25 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 7.4E-33 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 SMART SM00883 1 93 1.9E-51 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 Gene3D G3DSA:2.30.33.40 1 94 3.7E-36 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 PRINTS PR00297 10kDa chaperonin signature 24 45 5.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 PRINTS PR00297 10kDa chaperonin signature 59 71 5.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 PRINTS PR00297 10kDa chaperonin signature 2 17 5.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS09145 f3ac39e594c5740a121451e7c8241213 94 PRINTS PR00297 10kDa chaperonin signature 80 93 5.0E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CPF12_RS05215 26af77d195e27d2d05eeba8547ee4428 481 Gene3D G3DSA:1.10.10.10 3 68 1.4E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05215 26af77d195e27d2d05eeba8547ee4428 481 Gene3D G3DSA:1.10.10.10 80 142 8.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05215 26af77d195e27d2d05eeba8547ee4428 481 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 11 49 3.4E-6 T 28-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain CPF12_RS05215 26af77d195e27d2d05eeba8547ee4428 481 Pfam PF05043 Mga helix-turn-helix domain 73 156 9.7E-19 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS08185 6f41fe647e02d117d3a3092b79a84afb 271 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 30 267 2.8E-62 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CPF12_RS08185 6f41fe647e02d117d3a3092b79a84afb 271 Gene3D G3DSA:3.40.50.1820 35 271 4.8E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08185 6f41fe647e02d117d3a3092b79a84afb 271 SUPERFAMILY SSF53474 37 251 5.35E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS03220 eb8a072fa926548615fa2d6be0f8c7ab 172 Gene3D G3DSA:3.40.630.30 10 172 1.4E-28 T 28-03-2018 CPF12_RS03220 eb8a072fa926548615fa2d6be0f8c7ab 172 Pfam PF00583 Acetyltransferase (GNAT) family 58 145 6.7E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS03220 eb8a072fa926548615fa2d6be0f8c7ab 172 SUPERFAMILY SSF55729 14 171 6.0E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS02240 6d228babb52e599cb58fb0a3f8c2844c 312 Pfam PF13349 Putative adhesin 53 306 1.8E-30 T 28-03-2018 IPR025164 Putative adhesin CPF12_RS01815 14226bc6d45a8ece810c22e993362502 282 Gene3D G3DSA:3.40.50.10750 98 252 3.0E-34 T 28-03-2018 CPF12_RS01815 14226bc6d45a8ece810c22e993362502 282 SUPERFAMILY SSF53659 9 278 6.24E-49 T 28-03-2018 CPF12_RS01815 14226bc6d45a8ece810c22e993362502 282 PIRSF PIRSF000428 4 282 5.7E-63 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CPF12_RS01815 14226bc6d45a8ece810c22e993362502 282 Pfam PF01515 Phosphate acetyl/butaryl transferase 58 272 1.5E-38 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CPF12_RS01085 1eb39c9ba0cd0a89e0c97d05b5066520 264 PIRSF PIRSF003092 1 264 2.2E-89 T 28-03-2018 IPR025501 ATP binding protein MinD CPF12_RS01085 1eb39c9ba0cd0a89e0c97d05b5066520 264 SUPERFAMILY SSF52540 5 261 5.4E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01085 1eb39c9ba0cd0a89e0c97d05b5066520 264 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 219 9.0E-25 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CPF12_RS01085 1eb39c9ba0cd0a89e0c97d05b5066520 264 Gene3D G3DSA:3.40.50.300 1 241 3.6E-55 T 28-03-2018 CPF12_RS01085 1eb39c9ba0cd0a89e0c97d05b5066520 264 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 260 2.2E-117 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CPF12_RS07335 8c5110d3e1c1eef3e81139c1ac80c49d 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS07335 8c5110d3e1c1eef3e81139c1ac80c49d 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS07335 8c5110d3e1c1eef3e81139c1ac80c49d 181 Gene3D G3DSA:1.10.10.60 2 47 6.5E-12 T 28-03-2018 CPF12_RS07335 8c5110d3e1c1eef3e81139c1ac80c49d 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 5.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS07335 8c5110d3e1c1eef3e81139c1ac80c49d 181 Gene3D G3DSA:1.10.10.60 48 133 2.4E-8 T 28-03-2018 CPF12_RS07335 8c5110d3e1c1eef3e81139c1ac80c49d 181 SUPERFAMILY SSF46689 7 72 1.51E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS03710 a9b090cb610bc1a915f8f12155b224b9 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 266 4.1E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CPF12_RS03710 a9b090cb610bc1a915f8f12155b224b9 322 Gene3D G3DSA:3.40.50.300 5 319 2.5E-77 T 28-03-2018 CPF12_RS03710 a9b090cb610bc1a915f8f12155b224b9 322 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS03710 a9b090cb610bc1a915f8f12155b224b9 322 SUPERFAMILY SSF52540 8 253 1.3E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03710 a9b090cb610bc1a915f8f12155b224b9 322 SMART SM00382 38 232 3.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03710 a9b090cb610bc1a915f8f12155b224b9 322 Pfam PF00005 ABC transporter 30 182 7.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 330 1.6E-135 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 SMART SM00829 12 328 1.1E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 SUPERFAMILY SSF51735 119 296 3.18E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 Gene3D G3DSA:3.40.50.720 154 271 1.5E-14 T 28-03-2018 CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 89 8.4E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 Gene3D G3DSA:3.90.180.10 1 153 4.1E-33 T 28-03-2018 CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 Pfam PF00107 Zinc-binding dehydrogenase 162 275 2.8E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CPF12_RS03110 8249a352ce8a7543bc1f4cbea62f3d24 330 SUPERFAMILY SSF50129 5 146 5.63E-39 T 28-03-2018 IPR011032 GroES-like CPF12_RS11255 91bfbecb65a6b31f882e78dfeb53029f 122 Pfam PF13273 Protein of unknown function (DUF4064) 17 98 3.1E-10 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CPF12_RS02825 10e2e96800d7146a3c00e6ff11bdfe82 213 PIRSF PIRSF011560 2 190 1.1E-49 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 CPF12_RS02825 10e2e96800d7146a3c00e6ff11bdfe82 213 Pfam PF06338 ComK protein 7 152 1.7E-42 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 CPF12_RS11780 7ab95c072f8706df29457ba7ec6050e7 164 Pfam PF13671 AAA domain 4 118 1.5E-10 T 28-03-2018 CPF12_RS11780 7ab95c072f8706df29457ba7ec6050e7 164 SUPERFAMILY SSF52540 1 139 3.44E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11780 7ab95c072f8706df29457ba7ec6050e7 164 Gene3D G3DSA:3.40.50.300 1 151 1.7E-13 T 28-03-2018 CPF12_RS02790 dee17fd46346c92d90f9e9cde08221bb 102 SUPERFAMILY SSF117916 2 100 2.49E-33 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CPF12_RS02790 dee17fd46346c92d90f9e9cde08221bb 102 Gene3D G3DSA:3.30.300.130 2 101 5.6E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CPF12_RS02790 dee17fd46346c92d90f9e9cde08221bb 102 Pfam PF01883 Iron-sulfur cluster assembly protein 7 80 4.5E-22 T 28-03-2018 IPR002744 MIP18 family-like CPF12_RS08450 b25be883a37c001658cbb3e1ca890a69 143 Pfam PF04186 FxsA cytoplasmic membrane protein 9 111 5.2E-18 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CPF12_RS07795 dd23e480830f938acf9b387d2ca4f315 103 SUPERFAMILY SSF52833 8 100 3.52E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS07795 dd23e480830f938acf9b387d2ca4f315 103 Gene3D G3DSA:3.40.30.10 2 103 1.4E-13 T 28-03-2018 CPF12_RS07795 dd23e480830f938acf9b387d2ca4f315 103 Pfam PF00085 Thioredoxin 4 90 4.6E-13 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CPF12_RS09900 d3dd5990545838028dc4f93e846536d1 371 Gene3D G3DSA:3.40.1830.10 2 164 9.6E-41 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CPF12_RS09900 d3dd5990545838028dc4f93e846536d1 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 337 1.4E-60 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CPF12_RS09900 d3dd5990545838028dc4f93e846536d1 371 SUPERFAMILY SSF144052 1 360 7.98E-108 T 28-03-2018 CPF12_RS03915 4527bfd3d41ab7835358871bda209d46 230 SUPERFAMILY SSF52540 2 216 1.92E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03915 4527bfd3d41ab7835358871bda209d46 230 Pfam PF00005 ABC transporter 16 157 8.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03915 4527bfd3d41ab7835358871bda209d46 230 Gene3D G3DSA:3.40.50.300 1 225 2.9E-58 T 28-03-2018 CPF12_RS03915 4527bfd3d41ab7835358871bda209d46 230 SMART SM00382 25 206 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03915 4527bfd3d41ab7835358871bda209d46 230 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS02450 8d1e4cf727d0289bde7a4d308094e8f1 247 SUPERFAMILY SSF53474 2 243 9.81E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS02450 8d1e4cf727d0289bde7a4d308094e8f1 247 Gene3D G3DSA:3.40.50.1820 1 247 4.3E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS02450 8d1e4cf727d0289bde7a4d308094e8f1 247 Pfam PF00756 Putative esterase 10 150 1.2E-17 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CPF12_RS03585 a9c40867b0b03e77bdc429a366784bf8 348 Pfam PF13303 Phosphotransferase system, EIIC 14 344 3.5E-92 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04790 65a8a05e6619c3f048b5680eb8d6edd6 611 Gene3D G3DSA:3.40.720.10 240 536 3.8E-20 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CPF12_RS04790 65a8a05e6619c3f048b5680eb8d6edd6 611 SUPERFAMILY SSF53649 315 496 1.07E-15 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS04790 65a8a05e6619c3f048b5680eb8d6edd6 611 Pfam PF00884 Sulfatase 249 523 2.9E-32 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CPF12_RS03890 ff923c5886403429ce9325b5778d2ebf 303 Pfam PF12181 DNA binding domain of the motility gene repressor (MogR) 21 149 5.5E-43 T 28-03-2018 IPR021009 Motility repressor, MogR CPF12_RS09305 e3f2069f200426c351259417be6213e8 248 PIRSF PIRSF015601 1 248 2.2E-61 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS09305 e3f2069f200426c351259417be6213e8 248 Pfam PF04452 RNA methyltransferase 22 244 1.1E-68 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS09305 e3f2069f200426c351259417be6213e8 248 Gene3D G3DSA:3.40.1280.10 1 248 1.1E-73 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CPF12_RS09305 e3f2069f200426c351259417be6213e8 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 10 247 2.9E-58 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CPF12_RS09305 e3f2069f200426c351259417be6213e8 248 SUPERFAMILY SSF75217 72 247 2.31E-52 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CPF12_RS09305 e3f2069f200426c351259417be6213e8 248 SUPERFAMILY SSF88697 1 68 3.23E-10 T 28-03-2018 IPR015947 PUA-like domain CPF12_RS03815 b528681b9e93bb78d10fd122d00c7213 620 Gene3D G3DSA:2.60.40.10 422 499 2.2E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS03815 b528681b9e93bb78d10fd122d00c7213 620 Gene3D G3DSA:2.60.40.10 340 419 0.0023 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS03815 b528681b9e93bb78d10fd122d00c7213 620 Gene3D G3DSA:2.60.40.10 250 339 0.046 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS03815 b528681b9e93bb78d10fd122d00c7213 620 Pfam PF07523 Bacterial Ig-like domain (group 3) 344 408 1.1E-7 T 28-03-2018 IPR022038 Bacterial Ig-like domain CPF12_RS03815 b528681b9e93bb78d10fd122d00c7213 620 Pfam PF07523 Bacterial Ig-like domain (group 3) 426 496 2.5E-16 T 28-03-2018 IPR022038 Bacterial Ig-like domain CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 Pfam PF00005 ABC transporter 27 166 1.7E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 Pfam PF00005 ABC transporter 280 411 9.8E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 SMART SM00382 36 214 3.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 SMART SM00382 285 461 1.5E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 SUPERFAMILY SSF52540 260 462 8.32E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 SUPERFAMILY SSF52540 13 230 1.98E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 Gene3D G3DSA:3.40.50.300 254 466 1.7E-41 T 28-03-2018 CPF12_RS06275 c23e6f98d177545f9e213b50b6fa1498 467 Gene3D G3DSA:3.40.50.300 6 236 2.7E-45 T 28-03-2018 CPF12_RS10925 08ebe8b3419b8559b726e43b109f81b1 199 Pfam PF12822 ECF transporter, substrate-specific component 10 186 2.1E-29 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 Gene3D G3DSA:3.90.650.10 169 346 2.1E-59 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 Gene3D G3DSA:3.30.1330.10 30 159 2.5E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 4 346 46.417 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 334 2.3E-135 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 160 3.3E-17 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 SUPERFAMILY SSF56042 170 342 1.79E-57 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 342 1.5E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CPF12_RS08710 f25ac1492a2786355a6adbc5bd8a2b3d 346 SUPERFAMILY SSF55326 5 167 1.64E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CPF12_RS08105 c0d1363dd490d0ec08caf013c548916a 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 248 3.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS08105 c0d1363dd490d0ec08caf013c548916a 265 SUPERFAMILY SSF161098 7 251 7.76E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS08105 c0d1363dd490d0ec08caf013c548916a 265 Gene3D G3DSA:1.10.3720.10 9 263 1.1E-36 T 28-03-2018 CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 50 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.3E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 Gene3D G3DSA:1.10.10.60 42 133 9.9E-11 T 28-03-2018 CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 SUPERFAMILY SSF46689 4 67 4.34E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS10800 b1c8448b28396521386b2edae06c0517 298 Gene3D G3DSA:1.10.10.60 2 41 1.2E-16 T 28-03-2018 CPF12_RS09435 17875c2599a5676df8e18501872c59e5 82 Gene3D G3DSA:3.30.70.20 3 81 1.1E-6 T 28-03-2018 CPF12_RS09435 17875c2599a5676df8e18501872c59e5 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.8E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CPF12_RS09435 17875c2599a5676df8e18501872c59e5 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 2.8E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CPF12_RS09435 17875c2599a5676df8e18501872c59e5 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.8E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CPF12_RS09435 17875c2599a5676df8e18501872c59e5 82 SUPERFAMILY SSF54862 4 66 1.03E-10 T 28-03-2018 CPF12_RS09435 17875c2599a5676df8e18501872c59e5 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 68 1.4E-14 T 28-03-2018 CPF12_RS12190 7e1f49b4b59b5b9e525668fc66e3f232 94 Gene3D G3DSA:3.30.1230.10 1 94 2.3E-25 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CPF12_RS12190 7e1f49b4b59b5b9e525668fc66e3f232 94 SUPERFAMILY SSF64376 4 89 3.14E-24 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CPF12_RS12190 7e1f49b4b59b5b9e525668fc66e3f232 94 Pfam PF04296 Protein of unknown function (DUF448) 9 82 7.4E-23 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CPF12_RS05160 033b63527b970075ce2de6731bb3b4e0 179 Pfam PF12822 ECF transporter, substrate-specific component 10 158 2.0E-11 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CPF12_RS05160 033b63527b970075ce2de6731bb3b4e0 179 TIGRFAM TIGR04518 ECF_S_folT_fam: ECF transporter S component, folate family 5 162 1.3E-36 T 28-03-2018 IPR030949 ECF transporter S component, folate family CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 Pfam PF00226 DnaJ domain 5 66 7.4E-26 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 Gene3D G3DSA:2.60.260.20 198 310 1.5E-32 T 28-03-2018 CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 SMART SM00271 4 61 7.2E-30 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 Gene3D G3DSA:2.60.260.20 117 197 1.5E-20 T 28-03-2018 CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 SUPERFAMILY SSF46565 1 104 5.76E-36 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 SUPERFAMILY SSF49493 113 205 4.84E-18 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 SUPERFAMILY SSF49493 202 287 1.96E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 Gene3D G3DSA:1.10.287.110 1 115 4.2E-36 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 PRINTS PR00625 DnaJ domain signature 25 40 3.3E-30 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 PRINTS PR00625 DnaJ domain signature 7 25 3.3E-30 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 PRINTS PR00625 DnaJ domain signature 41 61 3.3E-30 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 PRINTS PR00625 DnaJ domain signature 61 80 3.3E-30 T 28-03-2018 IPR001623 DnaJ domain CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 311 27.295 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CPF12_RS09295 9a1f7138f55f33e11f986600b95be140 315 Pfam PF01556 DnaJ C terminal domain 119 277 7.0E-43 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CPF12_RS04065 497746a3273772efdb25b430018c8a80 280 Pfam PF13731 WxL domain surface cell wall-binding 37 273 1.5E-57 T 28-03-2018 IPR027994 WxL domain CPF12_RS01285 166217084c63200011a0f58b81f49a54 797 Pfam PF10651 Domain of unknown function (DUF2479) 5 141 1.3E-24 T 28-03-2018 IPR018913 Domain of unknown function DUF2479 CPF12_RS01285 166217084c63200011a0f58b81f49a54 797 Gene3D G3DSA:2.120.10.30 220 794 5.7E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CPF12_RS09655 ee3fba7104acac417af0a5d4f7dbc2c6 124 Pfam PF06993 Protein of unknown function (DUF1304) 10 119 1.2E-39 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CPF12_RS02820 33f51492d88a514e8715b20bb2705f01 84 Pfam PF08858 IDEAL domain 42 73 3.4E-6 T 28-03-2018 IPR014957 IDEAL domain CPF12_RS04550 566cbd082376e30b54d5291147bb7e3f 254 Gene3D G3DSA:3.40.50.1820 2 253 1.8E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS04550 566cbd082376e30b54d5291147bb7e3f 254 Pfam PF00326 Prolyl oligopeptidase family 95 250 2.0E-12 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CPF12_RS04550 566cbd082376e30b54d5291147bb7e3f 254 SUPERFAMILY SSF53474 12 250 3.1E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS04895 37977c0cb88e57c3bf3d4e9dbd802c45 270 Gene3D G3DSA:3.60.21.10 41 266 2.3E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS04895 37977c0cb88e57c3bf3d4e9dbd802c45 270 Pfam PF00149 Calcineurin-like phosphoesterase 44 210 7.8E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CPF12_RS04895 37977c0cb88e57c3bf3d4e9dbd802c45 270 SUPERFAMILY SSF56300 44 266 3.53E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS08765 fece47019c53232a64db3a6729153994 230 SUPERFAMILY SSF52172 2 125 6.26E-40 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS08765 fece47019c53232a64db3a6729153994 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 3.2E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS08765 fece47019c53232a64db3a6729153994 230 SMART SM00862 152 228 7.8E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS08765 fece47019c53232a64db3a6729153994 230 Gene3D G3DSA:1.10.10.10 130 230 3.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08765 fece47019c53232a64db3a6729153994 230 Pfam PF00072 Response regulator receiver domain 5 115 4.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS08765 fece47019c53232a64db3a6729153994 230 SUPERFAMILY SSF46894 130 229 7.37E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS08765 fece47019c53232a64db3a6729153994 230 SMART SM00448 3 114 2.0E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS08765 fece47019c53232a64db3a6729153994 230 Gene3D G3DSA:3.40.50.2300 1 129 2.8E-36 T 28-03-2018 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 286 2.9E-98 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 2.6E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 2.6E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 PRINTS PR00126 ATP synthase gamma subunit signature 72 91 2.6E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 2.6E-33 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 Pfam PF00231 ATP synthase 4 286 2.2E-93 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 SUPERFAMILY SSF52943 2 286 3.01E-86 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 34.503 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 Gene3D G3DSA:1.10.287.80 238 281 4.4E-15 T 28-03-2018 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 Gene3D G3DSA:3.40.1380.10 27 237 4.4E-69 T 28-03-2018 CPF12_RS06490 3a66c09c5e6be0234f6b2f06d945a305 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 SUPERFAMILY SSF47384 234 315 2.16E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 316 1.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 1.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 1.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 1.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 1.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 SUPERFAMILY SSF55874 307 475 5.5E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 Gene3D G3DSA:3.30.565.10 321 482 6.5E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 SMART SM00387 362 474 9.5E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 Gene3D G3DSA:1.10.287.130 240 313 6.8E-14 T 28-03-2018 CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 471 7.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS00980 c25cf9d4e358e70157af741730bd1336 491 SMART SM00388 250 317 3.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CPF12_RS05365 3397ef02823330a8d7506a4c9c3cdc3e 334 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 213 266 7.6E-17 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CPF12_RS05365 3397ef02823330a8d7506a4c9c3cdc3e 334 PIRSF PIRSF006483 1 275 1.9E-81 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CPF12_RS05365 3397ef02823330a8d7506a4c9c3cdc3e 334 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 2 207 4.4E-51 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CPF12_RS05840 fb7574f5267e30265d64bc8f43e98456 157 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 3.5E-43 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CPF12_RS05840 fb7574f5267e30265d64bc8f43e98456 157 SUPERFAMILY SSF55083 1 136 8.24E-51 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CPF12_RS05840 fb7574f5267e30265d64bc8f43e98456 157 Gene3D G3DSA:3.30.70.560 1 147 1.2E-54 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CPF12_RS05840 fb7574f5267e30265d64bc8f43e98456 157 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CPF12_RS05840 fb7574f5267e30265d64bc8f43e98456 157 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 9.4E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CPF12_RS09570 84bb544bfdad8c38cdd1cbf5417cd633 183 Pfam PF08858 IDEAL domain 137 170 1.5E-5 T 28-03-2018 IPR014957 IDEAL domain CPF12_RS09570 84bb544bfdad8c38cdd1cbf5417cd633 183 Pfam PF08864 UPF0302 domain 8 112 8.4E-35 T 28-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CPF12_RS09570 84bb544bfdad8c38cdd1cbf5417cd633 183 PIRSF PIRSF007165 2 180 2.9E-46 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CPF12_RS04740 8b5a20d5ab9e98649f43649b1f6918f2 406 Pfam PF02378 Phosphotransferase system, EIIC 29 349 4.5E-69 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04740 8b5a20d5ab9e98649f43649b1f6918f2 406 PIRSF PIRSF006351 1 406 4.7E-127 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CPF12_RS04740 8b5a20d5ab9e98649f43649b1f6918f2 406 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 405 5.8E-140 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CPF12_RS04740 8b5a20d5ab9e98649f43649b1f6918f2 406 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 405 5.8E-140 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 Gene3D G3DSA:3.30.1130.10 55 186 9.1E-53 T 28-03-2018 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 SUPERFAMILY SSF55620 4 186 2.08E-72 T 28-03-2018 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 Pfam PF01227 GTP cyclohydrolase I 10 185 4.8E-75 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 186 1.5E-72 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 64 80 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 Gene3D G3DSA:1.10.286.10 6 54 4.8E-23 T 28-03-2018 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 113 123 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CPF12_RS09490 1bcedd299128ebb6f2b42c8b9783a5fb 186 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 186 40.076 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CPF12_RS02360 542d43abc59086a3cf12d8fbd4839762 200 SUPERFAMILY SSF55469 4 199 2.75E-69 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CPF12_RS02360 542d43abc59086a3cf12d8fbd4839762 200 Gene3D G3DSA:3.40.109.10 3 199 3.1E-26 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CPF12_RS02360 542d43abc59086a3cf12d8fbd4839762 200 Pfam PF00881 Nitroreductase family 9 177 4.8E-17 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CPF12_RS02785 fa6f67b14db21ba8c26b3a618909c047 623 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 27 616 2.9E-178 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CPF12_RS02785 fa6f67b14db21ba8c26b3a618909c047 623 SUPERFAMILY SSF51998 32 597 1.79E-185 T 28-03-2018 CPF12_RS02785 fa6f67b14db21ba8c26b3a618909c047 623 ProSitePatterns PS00850 Glycine radical domain signature. 587 595 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CPF12_RS02785 fa6f67b14db21ba8c26b3a618909c047 623 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 26 616 7.1E-179 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CPF12_RS02785 fa6f67b14db21ba8c26b3a618909c047 623 Gene3D G3DSA:3.20.70.20 32 598 1.4E-195 T 28-03-2018 CPF12_RS02470 68b9998b09cdd6477ba16fbcf2183aa4 415 Gene3D G3DSA:3.40.190.10 164 345 1.5E-35 T 28-03-2018 CPF12_RS02470 68b9998b09cdd6477ba16fbcf2183aa4 415 Pfam PF13416 Bacterial extracellular solute-binding protein 51 354 2.7E-52 T 28-03-2018 CPF12_RS02470 68b9998b09cdd6477ba16fbcf2183aa4 415 SUPERFAMILY SSF53850 20 410 1.63E-82 T 28-03-2018 CPF12_RS02470 68b9998b09cdd6477ba16fbcf2183aa4 415 Gene3D G3DSA:3.40.190.10 35 163 3.1E-31 T 28-03-2018 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 Gene3D G3DSA:3.40.630.10 6 194 2.3E-26 T 28-03-2018 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 Gene3D G3DSA:3.30.70.360 207 287 2.6E-10 T 28-03-2018 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 463 1.8E-167 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 Gene3D G3DSA:3.30.70.360 288 374 1.5E-25 T 28-03-2018 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 SUPERFAMILY SSF55031 187 376 3.74E-47 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 SUPERFAMILY SSF53187 5 187 1.49E-63 T 28-03-2018 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 SUPERFAMILY SSF53187 385 467 1.49E-63 T 28-03-2018 CPF12_RS01475 846049082f07a1b4979d9d354f2ddf11 468 Pfam PF01546 Peptidase family M20/M25/M40 86 464 1.5E-29 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS10805 82b4df980aacde99c2bd2ce1f05f0386 370 SUPERFAMILY SSF110738 1 364 4.18E-94 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CPF12_RS10805 82b4df980aacde99c2bd2ce1f05f0386 370 Gene3D G3DSA:3.90.1510.10 40 269 5.5E-67 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CPF12_RS10805 82b4df980aacde99c2bd2ce1f05f0386 370 PIRSF PIRSF006078 1 368 1.4E-97 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CPF12_RS10805 82b4df980aacde99c2bd2ce1f05f0386 370 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 366 3.9E-101 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CPF12_RS10805 82b4df980aacde99c2bd2ce1f05f0386 370 Pfam PF02595 Glycerate kinase family 3 366 9.4E-108 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CPF12_RS01785 19df8d38d80ad3e0913cda620175a08c 444 Pfam PF05525 Branched-chain amino acid transport protein 9 437 5.2E-147 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CPF12_RS01785 19df8d38d80ad3e0913cda620175a08c 444 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 423 3.3E-135 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 PRINTS PR00173 Glutamate-aspartate symporter signature 368 387 9.3E-14 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 PRINTS PR00173 Glutamate-aspartate symporter signature 395 415 9.3E-14 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 PRINTS PR00173 Glutamate-aspartate symporter signature 181 203 9.3E-14 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 9.3E-14 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 SUPERFAMILY SSF118215 30 441 1.31E-86 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 Gene3D G3DSA:1.10.3860.10 19 448 1.1E-81 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS01655 43ca97fe61a3a8017c7505d4465093c0 460 Pfam PF00375 Sodium:dicarboxylate symporter family 32 440 1.0E-90 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CPF12_RS00490 c80b95562fb1fae972d8dac4152b01b5 221 Pfam PF04237 YjbR 116 217 2.0E-12 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CPF12_RS00490 c80b95562fb1fae972d8dac4152b01b5 221 SUPERFAMILY SSF142906 101 221 4.84E-27 T 28-03-2018 CPF12_RS08930 823e67f7c2ef2f8e337292e6fb44fb8c 379 PIRSF PIRSF005572 1 378 4.3E-111 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CPF12_RS08930 823e67f7c2ef2f8e337292e6fb44fb8c 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CPF12_RS08930 823e67f7c2ef2f8e337292e6fb44fb8c 379 Gene3D G3DSA:3.40.640.10 11 240 2.2E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS08930 823e67f7c2ef2f8e337292e6fb44fb8c 379 SUPERFAMILY SSF53383 1 373 9.35E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS08930 823e67f7c2ef2f8e337292e6fb44fb8c 379 Gene3D G3DSA:3.90.1150.10 241 379 8.5E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS08930 823e67f7c2ef2f8e337292e6fb44fb8c 379 Pfam PF00266 Aminotransferase class-V 2 359 2.5E-71 T 28-03-2018 IPR000192 Aminotransferase class V domain CPF12_RS05055 c2cd04decba687cacf8dbda21e2c437a 320 Pfam PF01032 FecCD transport family 34 316 7.4E-49 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS05055 c2cd04decba687cacf8dbda21e2c437a 320 SUPERFAMILY SSF81345 14 316 1.31E-51 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS05055 c2cd04decba687cacf8dbda21e2c437a 320 Gene3D G3DSA:1.10.3470.10 7 320 5.4E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS00485 e64111a279a8ce3ddd8bb0d35f9173fe 317 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00485 e64111a279a8ce3ddd8bb0d35f9173fe 317 SUPERFAMILY SSF52540 1 238 5.61E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00485 e64111a279a8ce3ddd8bb0d35f9173fe 317 Pfam PF00005 ABC transporter 18 163 4.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS00485 e64111a279a8ce3ddd8bb0d35f9173fe 317 SMART SM00382 26 213 5.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00485 e64111a279a8ce3ddd8bb0d35f9173fe 317 Gene3D G3DSA:3.40.50.300 1 272 2.1E-75 T 28-03-2018 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 Gene3D G3DSA:1.10.10.10 128 236 5.3E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 Gene3D G3DSA:3.40.50.2300 1 127 9.2E-40 T 28-03-2018 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 SMART SM00862 154 230 2.9E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 SMART SM00448 4 114 4.0E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 Pfam PF00072 Response regulator receiver domain 6 115 6.3E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 SUPERFAMILY SSF46894 136 231 3.21E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 2.6E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS05040 2cba3d934c2a24e29bb82ddfef9e3c92 236 SUPERFAMILY SSF52172 2 130 5.27E-44 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS09505 7c3732151bf42d03eaef8015ba381958 328 Gene3D G3DSA:1.10.600.10 4 328 1.7E-85 T 28-03-2018 IPR008949 Isoprenoid synthase domain CPF12_RS09505 7c3732151bf42d03eaef8015ba381958 328 Pfam PF00348 Polyprenyl synthetase 40 271 1.6E-63 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CPF12_RS09505 7c3732151bf42d03eaef8015ba381958 328 SUPERFAMILY SSF48576 11 326 1.92E-81 T 28-03-2018 IPR008949 Isoprenoid synthase domain CPF12_RS09505 7c3732151bf42d03eaef8015ba381958 328 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 90 104 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CPF12_RS09505 7c3732151bf42d03eaef8015ba381958 328 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 211 223 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CPF12_RS02530 4893fe14c646dd816120ee8e681c7401 249 Pfam PF03741 Integral membrane protein TerC family 15 202 1.8E-46 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CPF12_RS02530 4893fe14c646dd816120ee8e681c7401 249 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 241 4.3E-80 T 28-03-2018 IPR022493 Integral membrane YkoY CPF12_RS02560 6566369399159fa619e34dd40400c853 493 Pfam PF07690 Major Facilitator Superfamily 19 411 2.5E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 Gene3D G3DSA:1.20.1250.20 253 489 4.3E-30 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 SUPERFAMILY SSF103473 13 203 7.72E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS02560 6566369399159fa619e34dd40400c853 493 SUPERFAMILY SSF103473 464 488 7.72E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS02560 6566369399159fa619e34dd40400c853 493 SUPERFAMILY SSF103473 250 420 7.72E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS02560 6566369399159fa619e34dd40400c853 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 3.6E-10 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 3.6E-10 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 303 327 3.6E-10 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 401 420 3.6E-10 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 3.6E-10 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 Gene3D G3DSA:1.20.1250.20 4 202 6.5E-39 T 28-03-2018 CPF12_RS02560 6566369399159fa619e34dd40400c853 493 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 474 7.8E-81 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CPF12_RS03315 c8d8f375068d429bc9e724accddbcba9 103 PIRSF PIRSF000699 1 103 1.1E-37 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CPF12_RS03315 c8d8f375068d429bc9e724accddbcba9 103 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 99 8.1E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CPF12_RS03315 c8d8f375068d429bc9e724accddbcba9 103 SUPERFAMILY SSF46973 1 100 5.1E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CPF12_RS03315 c8d8f375068d429bc9e724accddbcba9 103 Gene3D G3DSA:1.20.58.80 2 100 1.7E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CPF12_RS05195 3a59adc541a5542ccd6211e94d8d34ce 302 Pfam PF01544 CorA-like Mg2+ transporter protein 10 298 2.7E-58 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CPF12_RS05195 3a59adc541a5542ccd6211e94d8d34ce 302 SUPERFAMILY SSF144083 238 298 1.06E-12 T 28-03-2018 CPF12_RS05195 3a59adc541a5542ccd6211e94d8d34ce 302 Gene3D G3DSA:1.20.58.340 121 235 2.5E-9 T 28-03-2018 CPF12_RS05195 3a59adc541a5542ccd6211e94d8d34ce 302 Gene3D G3DSA:1.20.58.340 236 300 1.1E-10 T 28-03-2018 CPF12_RS05195 3a59adc541a5542ccd6211e94d8d34ce 302 Gene3D G3DSA:3.30.460.20 3 116 2.0E-15 T 28-03-2018 CPF12_RS05195 3a59adc541a5542ccd6211e94d8d34ce 302 SUPERFAMILY SSF143865 8 237 5.62E-33 T 28-03-2018 CPF12_RS08045 85884e154bcdec45b4f7ce38c819128b 466 SMART SM00885 47 181 0.0098 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CPF12_RS08045 85884e154bcdec45b4f7ce38c819128b 466 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 131 430 1.2E-57 T 28-03-2018 IPR006500 DNA primase, phage/plasmid CPF12_RS08045 85884e154bcdec45b4f7ce38c819128b 466 Pfam PF08706 D5 N terminal like 130 179 1.1E-6 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CPF12_RS08045 85884e154bcdec45b4f7ce38c819128b 466 SUPERFAMILY SSF52540 188 330 1.93E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08045 85884e154bcdec45b4f7ce38c819128b 466 Gene3D G3DSA:3.40.50.300 158 361 4.5E-13 T 28-03-2018 CPF12_RS00340 b7f3a2e2930f55549271575bf3e8f8c7 305 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 295 7.9E-83 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CPF12_RS00340 b7f3a2e2930f55549271575bf3e8f8c7 305 Gene3D G3DSA:3.90.245.10 1 305 6.5E-98 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CPF12_RS00340 b7f3a2e2930f55549271575bf3e8f8c7 305 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 9 19 - T 28-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 CPF12_RS00340 b7f3a2e2930f55549271575bf3e8f8c7 305 SUPERFAMILY SSF53590 3 304 1.83E-94 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CPF12_RS08220 5d0be3e4f1c36e998be06856191c633b 244 Pfam PF07722 Peptidase C26 6 221 7.0E-70 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CPF12_RS08220 5d0be3e4f1c36e998be06856191c633b 244 SUPERFAMILY SSF52317 25 236 6.11E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS08220 5d0be3e4f1c36e998be06856191c633b 244 Gene3D G3DSA:3.40.50.880 1 243 2.7E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 301 50.967 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 Gene3D G3DSA:1.10.443.10 112 295 5.2E-47 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 11 89 2.6E-19 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 SUPERFAMILY SSF56349 13 293 3.24E-52 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 Pfam PF00589 Phage integrase family 114 287 5.3E-49 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 10 301 2.6E-106 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CPF12_RS11815 5831172d03d34269baf8e73228d624f3 301 Gene3D G3DSA:1.10.150.130 5 109 9.6E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CPF12_RS09690 08cb1ed9d7920960cc92c5f82c279c5b 107 Hamap MF_01448 UPF0473 protein . 13 102 17.639 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CPF12_RS09690 08cb1ed9d7920960cc92c5f82c279c5b 107 Pfam PF06949 Protein of unknown function (DUF1292) 22 100 2.5E-12 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CPF12_RS03750 32518cccd3dfd4c4d4df30b57b5c84b4 150 PIRSF PIRSF021320 2 150 1.1E-52 T 28-03-2018 IPR009326 Protein of unknown function DUF984 CPF12_RS03750 32518cccd3dfd4c4d4df30b57b5c84b4 150 Pfam PF04266 ASCH domain 35 149 4.1E-24 T 28-03-2018 IPR007374 ASCH domain CPF12_RS03750 32518cccd3dfd4c4d4df30b57b5c84b4 150 SUPERFAMILY SSF88697 4 149 6.96E-52 T 28-03-2018 IPR015947 PUA-like domain CPF12_RS03750 32518cccd3dfd4c4d4df30b57b5c84b4 150 SMART SM01022 27 149 3.2E-38 T 28-03-2018 IPR007374 ASCH domain CPF12_RS03750 32518cccd3dfd4c4d4df30b57b5c84b4 150 Gene3D G3DSA:3.10.400.10 4 150 4.0E-57 T 28-03-2018 CPF12_RS04480 3f255916b63028ef8a29fb78d5bc2db9 270 Gene3D G3DSA:3.40.190.10 31 160 1.9E-26 T 28-03-2018 CPF12_RS04480 3f255916b63028ef8a29fb78d5bc2db9 270 SMART SM00062 35 262 1.3E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS04480 3f255916b63028ef8a29fb78d5bc2db9 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 260 9.5E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS04480 3f255916b63028ef8a29fb78d5bc2db9 270 SUPERFAMILY SSF53850 6 262 7.95E-51 T 28-03-2018 CPF12_RS04480 3f255916b63028ef8a29fb78d5bc2db9 270 Gene3D G3DSA:3.40.190.10 161 268 8.1E-15 T 28-03-2018 CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 Pfam PF01230 HIT domain 13 110 5.0E-23 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 Gene3D G3DSA:1.20.5.1170 124 143 2.4E-6 T 28-03-2018 CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 SUPERFAMILY SSF54197 4 140 3.83E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 PRINTS PR00332 Histidine triad family signature 7 23 2.4E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 PRINTS PR00332 Histidine triad family signature 28 46 2.4E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 PRINTS PR00332 Histidine triad family signature 96 106 2.4E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CPF12_RS02855 b80a94b313a530d1eeaa4b0e0b637358 144 Gene3D G3DSA:3.30.428.10 8 123 3.7E-29 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CPF12_RS01570 1e2082bf5559ecd89a264ef76ae8b88c 448 Gene3D G3DSA:3.90.1150.10 338 448 5.5E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS01570 1e2082bf5559ecd89a264ef76ae8b88c 448 SUPERFAMILY SSF53383 4 445 1.09E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS01570 1e2082bf5559ecd89a264ef76ae8b88c 448 Pfam PF02347 Glycine cleavage system P-protein 5 444 1.7E-145 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CPF12_RS01570 1e2082bf5559ecd89a264ef76ae8b88c 448 PIRSF PIRSF006815 4 448 1.8E-178 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CPF12_RS01570 1e2082bf5559ecd89a264ef76ae8b88c 448 Gene3D G3DSA:3.40.640.10 85 337 4.1E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS01570 1e2082bf5559ecd89a264ef76ae8b88c 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 4 447 46.385 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CPF12_RS01410 60e651613710b8c9e99d9742aa0c7ce8 155 Pfam PF10702 Protein of unknown function (DUF2507) 12 133 1.1E-39 T 28-03-2018 IPR019642 Protein of unknown function DUF2507 CPF12_RS01410 60e651613710b8c9e99d9742aa0c7ce8 155 SUPERFAMILY SSF111126 11 119 1.46E-20 T 28-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CPF12_RS01410 60e651613710b8c9e99d9742aa0c7ce8 155 Gene3D G3DSA:3.30.1380.20 2 123 6.1E-19 T 28-03-2018 CPF12_RS10820 8ee0fab7548ff9e52a2d0a03b9aa679e 116 Pfam PF14272 Glycine-rich SFCGS 2 115 5.5E-62 T 28-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 CPF12_RS10820 8ee0fab7548ff9e52a2d0a03b9aa679e 116 TIGRFAM TIGR03577 EF_0830: conserved hypothetical protein EF_0830/AHA_3911 2 115 3.2E-65 T 28-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 4 490 4.0E-122 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 Pfam PF12161 HsdM N-terminal domain 5 157 2.7E-21 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 Pfam PF02384 N-6 DNA Methylase 168 476 5.2E-104 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 SUPERFAMILY SSF53335 5 42 3.23E-128 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 SUPERFAMILY SSF53335 86 509 3.23E-128 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 293 305 2.4E-20 T 28-03-2018 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 220 234 2.4E-20 T 28-03-2018 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 329 353 2.4E-20 T 28-03-2018 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 192 208 2.4E-20 T 28-03-2018 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 296 302 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CPF12_RS08275 6370f4f2255fc209702252d85b3ecb0a 525 Gene3D G3DSA:3.40.50.150 190 470 1.0E-71 T 28-03-2018 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 SMART SM00382 169 354 1.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 Gene3D G3DSA:2.40.50.140 5 125 8.1E-40 T 28-03-2018 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 159 362 3.4E-19 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 SMART SM00357 55 120 1.6E-16 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 SUPERFAMILY SSF52540 92 370 1.37E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 416 1.2E-190 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 Gene3D G3DSA:3.40.50.300 126 368 1.2E-47 T 28-03-2018 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 208.393 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 SMART SM00959 8 50 1.3E-9 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 SUPERFAMILY SSF68912 4 50 3.06E-8 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 SUPERFAMILY SSF50249 51 116 2.23E-6 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 Pfam PF07498 Rho termination factor, N-terminal domain 8 50 1.7E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CPF12_RS06420 3fc36f1e257538f9dca7943e386202c4 424 Pfam PF07497 Rho termination factor, RNA-binding domain 54 127 6.1E-30 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CPF12_RS03500 715a3371b2181be587c3db5cb5831b11 422 Pfam PF07687 Peptidase dimerisation domain 201 294 1.5E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS03500 715a3371b2181be587c3db5cb5831b11 422 SUPERFAMILY SSF53187 321 409 2.41E-37 T 28-03-2018 CPF12_RS03500 715a3371b2181be587c3db5cb5831b11 422 SUPERFAMILY SSF53187 35 213 2.41E-37 T 28-03-2018 CPF12_RS03500 715a3371b2181be587c3db5cb5831b11 422 SUPERFAMILY SSF55031 201 303 4.97E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS03500 715a3371b2181be587c3db5cb5831b11 422 Pfam PF01546 Peptidase family M20/M25/M40 98 397 1.6E-16 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS03500 715a3371b2181be587c3db5cb5831b11 422 Gene3D G3DSA:3.40.630.10 6 297 2.3E-41 T 28-03-2018 CPF12_RS00600 add7ec7d6424f7c3e3865e89cb25b751 483 Pfam PF02976 DNA mismatch repair enzyme MutH 72 180 2.5E-23 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CPF12_RS00600 add7ec7d6424f7c3e3865e89cb25b751 483 Gene3D G3DSA:3.40.600.10 8 247 5.9E-52 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CPF12_RS00600 add7ec7d6424f7c3e3865e89cb25b751 483 Gene3D G3DSA:3.40.600.10 248 483 3.9E-40 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CPF12_RS00600 add7ec7d6424f7c3e3865e89cb25b751 483 SUPERFAMILY SSF52980 257 482 3.91E-21 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CPF12_RS00600 add7ec7d6424f7c3e3865e89cb25b751 483 SUPERFAMILY SSF52980 22 246 2.09E-39 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CPF12_RS00600 add7ec7d6424f7c3e3865e89cb25b751 483 SMART SM00927 74 180 2.5E-11 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CPF12_RS11020 224ccd68444325723bd31f1c8fcaecc2 214 SUPERFAMILY SSF50685 155 195 2.89E-5 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CPF12_RS11020 224ccd68444325723bd31f1c8fcaecc2 214 Pfam PF01476 LysM domain 38 80 3.3E-13 T 28-03-2018 IPR018392 LysM domain CPF12_RS11020 224ccd68444325723bd31f1c8fcaecc2 214 Gene3D G3DSA:2.40.40.10 44 214 4.7E-40 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CPF12_RS11020 224ccd68444325723bd31f1c8fcaecc2 214 Pfam PF06725 3D domain 153 212 1.8E-19 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CPF12_RS11020 224ccd68444325723bd31f1c8fcaecc2 214 SMART SM00257 36 80 6.1E-15 T 28-03-2018 IPR018392 LysM domain CPF12_RS11020 224ccd68444325723bd31f1c8fcaecc2 214 SUPERFAMILY SSF54106 38 80 4.32E-10 T 28-03-2018 IPR018392 LysM domain CPF12_RS02040 9196dbe8f045f5f36b3378265708d037 125 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 43 122 1.2E-13 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CPF12_RS02040 9196dbe8f045f5f36b3378265708d037 125 Pfam PF04977 Septum formation initiator 51 111 4.3E-8 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CPF12_RS08485 eb66260faef27ec033ca8d8f82eaf6b8 199 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 198 28.864 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CPF12_RS08485 eb66260faef27ec033ca8d8f82eaf6b8 199 SUPERFAMILY SSF52540 1 189 7.57E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08485 eb66260faef27ec033ca8d8f82eaf6b8 199 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 188 1.9E-60 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CPF12_RS08485 eb66260faef27ec033ca8d8f82eaf6b8 199 Gene3D G3DSA:3.40.50.300 2 197 4.1E-43 T 28-03-2018 CPF12_RS08485 eb66260faef27ec033ca8d8f82eaf6b8 199 Pfam PF01121 Dephospho-CoA kinase 4 180 5.9E-60 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CPF12_RS07330 33c123a1532ac9101cc46450aedde51f 127 Pfam PF01381 Helix-turn-helix 11 65 5.7E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS07330 33c123a1532ac9101cc46450aedde51f 127 SMART SM00530 10 65 1.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS07330 33c123a1532ac9101cc46450aedde51f 127 Gene3D G3DSA:1.10.260.40 2 113 1.9E-21 T 28-03-2018 CPF12_RS07330 33c123a1532ac9101cc46450aedde51f 127 SUPERFAMILY SSF47413 5 69 9.12E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS06415 31d175b73ce657b0e2b52cf418320c10 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 418 7.1E-158 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS06415 31d175b73ce657b0e2b52cf418320c10 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 409 1.4E-86 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS06415 31d175b73ce657b0e2b52cf418320c10 422 SUPERFAMILY SSF55205 4 420 4.09E-129 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CPF12_RS06415 31d175b73ce657b0e2b52cf418320c10 422 Gene3D G3DSA:3.65.10.10 223 421 2.1E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS06415 31d175b73ce657b0e2b52cf418320c10 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 3 419 40.567 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS06415 31d175b73ce657b0e2b52cf418320c10 422 Gene3D G3DSA:3.65.10.10 23 222 3.3E-39 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 Gene3D G3DSA:1.10.10.60 43 177 2.4E-9 T 28-03-2018 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 SUPERFAMILY SSF46689 4 59 1.64E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 Gene3D G3DSA:1.10.10.60 3 42 2.7E-15 T 28-03-2018 CPF12_RS10710 39f70b98550ecfae0cf417e255bcdb20 294 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CPF12_RS03795 ef716fcd555a59b56ed49dc584597f35 172 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 8.4E-8 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS02980 b9b11977be5b59ee43ca10ba58261142 264 SUPERFAMILY SSF53850 3 259 7.85E-67 T 28-03-2018 CPF12_RS02980 b9b11977be5b59ee43ca10ba58261142 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 259 1.9E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS02980 b9b11977be5b59ee43ca10ba58261142 264 Gene3D G3DSA:3.40.190.10 3 151 2.2E-42 T 28-03-2018 CPF12_RS02980 b9b11977be5b59ee43ca10ba58261142 264 Gene3D G3DSA:3.40.190.10 152 262 1.1E-16 T 28-03-2018 CPF12_RS02980 b9b11977be5b59ee43ca10ba58261142 264 SMART SM00062 38 262 2.8E-72 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CPF12_RS02980 b9b11977be5b59ee43ca10ba58261142 264 SMART SM00079 38 261 1.9E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CPF12_RS06715 eb7ccf7b62237f781e50079d32efe6ae 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS06715 eb7ccf7b62237f781e50079d32efe6ae 250 SMART SM00382 28 229 4.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06715 eb7ccf7b62237f781e50079d32efe6ae 250 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 4 250 7.9E-122 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CPF12_RS06715 eb7ccf7b62237f781e50079d32efe6ae 250 SUPERFAMILY SSF52540 3 237 2.18E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06715 eb7ccf7b62237f781e50079d32efe6ae 250 Pfam PF00005 ABC transporter 21 175 1.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS06715 eb7ccf7b62237f781e50079d32efe6ae 250 Gene3D G3DSA:3.40.50.300 1 248 3.6E-58 T 28-03-2018 CPF12_RS03530 a82d4af3102f05a9ffeabf31b05bdf96 398 TIGRFAM TIGR01076 sortase_fam: sortase 116 249 2.6E-44 T 28-03-2018 IPR005754 Sortase family CPF12_RS03530 a82d4af3102f05a9ffeabf31b05bdf96 398 SUPERFAMILY SSF63817 108 246 2.88E-39 T 28-03-2018 IPR023365 Sortase domain CPF12_RS03530 a82d4af3102f05a9ffeabf31b05bdf96 398 Pfam PF04203 Sortase family 118 243 6.8E-20 T 28-03-2018 IPR005754 Sortase family CPF12_RS03530 a82d4af3102f05a9ffeabf31b05bdf96 398 Gene3D G3DSA:2.40.260.10 42 261 8.5E-44 T 28-03-2018 IPR023365 Sortase domain CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 SUPERFAMILY SSF46785 3 135 2.06E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 Gene3D G3DSA:1.10.10.10 1 137 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 SMART SM00347 24 123 2.7E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 3.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 3.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 3.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS07620 f721b93bc23554ba91b7503fc56b291b 137 Pfam PF13463 Winged helix DNA-binding domain 31 96 2.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS04515 54cd7420a88d34b8f5849ec48bffe064 34 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 2 34 2.2E-10 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CPF12_RS04105 6164e6ef5ad828f902f03e8f51768ac8 339 Gene3D G3DSA:1.10.3470.10 8 338 1.4E-64 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS04105 6164e6ef5ad828f902f03e8f51768ac8 339 Pfam PF01032 FecCD transport family 23 331 1.5E-90 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS04105 6164e6ef5ad828f902f03e8f51768ac8 339 SUPERFAMILY SSF81345 7 333 5.1E-81 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS07855 01b31584b5e7cd015e51d631cfa0bb62 462 Gene3D G3DSA:3.30.1360.60 7 81 3.2E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS07855 01b31584b5e7cd015e51d631cfa0bb62 462 Pfam PF02378 Phosphotransferase system, EIIC 111 391 1.5E-29 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS07855 01b31584b5e7cd015e51d631cfa0bb62 462 SUPERFAMILY SSF55604 11 86 3.27E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS07855 01b31584b5e7cd015e51d631cfa0bb62 462 Pfam PF00367 phosphotransferase system, EIIB 14 40 3.7E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS06945 1648f2704d5cbe158cf243721094fe55 478 Gene3D G3DSA:1.10.10.10 93 157 0.1 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06945 1648f2704d5cbe158cf243721094fe55 478 Gene3D G3DSA:1.10.10.10 7 71 0.074 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06945 1648f2704d5cbe158cf243721094fe55 478 Pfam PF05043 Mga helix-turn-helix domain 87 162 3.6E-14 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS02020 8d565681d168803721b375025975f400 450 Gene3D G3DSA:3.40.1190.10 102 308 4.5E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS02020 8d565681d168803721b375025975f400 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 375 5.7E-6 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS02020 8d565681d168803721b375025975f400 450 SUPERFAMILY SSF53244 310 449 1.19E-41 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CPF12_RS02020 8d565681d168803721b375025975f400 450 SUPERFAMILY SSF51984 10 100 4.97E-18 T 28-03-2018 CPF12_RS02020 8d565681d168803721b375025975f400 450 SUPERFAMILY SSF53623 103 308 7.33E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS02020 8d565681d168803721b375025975f400 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 447 1.5E-128 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS02020 8d565681d168803721b375025975f400 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 449 36.217 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CPF12_RS02020 8d565681d168803721b375025975f400 450 Gene3D G3DSA:3.40.50.720 1 101 8.9E-18 T 28-03-2018 CPF12_RS02020 8d565681d168803721b375025975f400 450 Gene3D G3DSA:3.90.190.20 315 448 2.3E-33 T 28-03-2018 CPF12_RS02020 8d565681d168803721b375025975f400 450 Pfam PF08245 Mur ligase middle domain 117 291 2.5E-37 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CPF12_RS07120 ac99958e594bc220e16494248b85de67 113 Pfam PF00575 S1 RNA binding domain 3 76 3.3E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS07120 ac99958e594bc220e16494248b85de67 113 Gene3D G3DSA:2.40.50.140 7 98 1.2E-24 T 28-03-2018 CPF12_RS07120 ac99958e594bc220e16494248b85de67 113 SUPERFAMILY SSF50249 4 86 4.36E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS07120 ac99958e594bc220e16494248b85de67 113 SMART SM00316 5 76 1.3E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS00395 66a8c22a48d02cd3f080dad17ada65f3 239 SUPERFAMILY SSF46894 56 110 1.02E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS00395 66a8c22a48d02cd3f080dad17ada65f3 239 Gene3D G3DSA:1.10.10.10 57 193 2.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00395 66a8c22a48d02cd3f080dad17ada65f3 239 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 170 237 3.1E-22 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CPF12_RS09365 cc37c27d8a67c00a94507f4eab2c1156 389 PIRSF PIRSF026508 21 389 5.5E-111 T 28-03-2018 IPR008863 Toxic anion resistance CPF12_RS09365 cc37c27d8a67c00a94507f4eab2c1156 389 Gene3D G3DSA:1.10.287.1060 52 170 9.6E-5 T 28-03-2018 CPF12_RS09365 cc37c27d8a67c00a94507f4eab2c1156 389 Pfam PF05816 Toxic anion resistance protein (TelA) 59 386 1.6E-117 T 28-03-2018 IPR008863 Toxic anion resistance CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.8E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 Pfam PF03466 LysR substrate binding domain 89 288 1.3E-30 T 28-03-2018 IPR005119 LysR, substrate-binding CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 Gene3D G3DSA:3.40.190.10 91 174 1.0E-16 T 28-03-2018 CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 SUPERFAMILY SSF46785 1 85 6.65E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 Gene3D G3DSA:3.40.190.10 175 259 9.8E-12 T 28-03-2018 CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 Gene3D G3DSA:1.10.10.10 1 90 5.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04460 2ffddb15741a30ea0a52aacc299c7dc1 297 SUPERFAMILY SSF53850 91 276 3.86E-25 T 28-03-2018 CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 Gene3D G3DSA:3.20.20.140 1 258 1.2E-89 T 28-03-2018 CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 Pfam PF01026 TatD related DNase 3 252 2.4E-80 T 28-03-2018 IPR001130 TatD family GO:0016788 CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 SUPERFAMILY SSF51556 2 255 1.13E-89 T 28-03-2018 IPR032466 Metal-dependent hydrolase CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 PIRSF PIRSF005902 1 257 1.1E-82 T 28-03-2018 IPR001130 TatD family GO:0016788 CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 6.7E-91 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CPF12_RS05710 a53ab7ded0955333d44cdac8f8678391 258 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CPF12_RS05425 c7992f663e0b6ffecdde474f38853d34 420 Gene3D G3DSA:1.10.3210.10 195 419 2.0E-14 T 28-03-2018 CPF12_RS05425 c7992f663e0b6ffecdde474f38853d34 420 SUPERFAMILY SSF109604 352 415 2.12E-7 T 28-03-2018 CPF12_RS05425 c7992f663e0b6ffecdde474f38853d34 420 SUPERFAMILY SSF109604 288 313 2.12E-7 T 28-03-2018 CPF12_RS11960 c3d853afc301cb521894271ad08ab07f 238 SUPERFAMILY SSF52540 5 221 6.01E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11960 c3d853afc301cb521894271ad08ab07f 238 Gene3D G3DSA:3.40.50.300 3 237 7.2E-41 T 28-03-2018 CPF12_RS11960 c3d853afc301cb521894271ad08ab07f 238 Pfam PF00005 ABC transporter 23 160 2.3E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11960 c3d853afc301cb521894271ad08ab07f 238 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11960 c3d853afc301cb521894271ad08ab07f 238 SMART SM00382 28 208 8.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS06820 0112bd22551cd40cdf98e334d3102ba3 172 SUPERFAMILY SSF110391 1 167 8.24E-57 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CPF12_RS06820 0112bd22551cd40cdf98e334d3102ba3 172 Gene3D G3DSA:3.20.20.400 1 167 2.9E-64 T 28-03-2018 CPF12_RS06820 0112bd22551cd40cdf98e334d3102ba3 172 PIRSF PIRSF016897 1 172 2.8E-59 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CPF12_RS06820 0112bd22551cd40cdf98e334d3102ba3 172 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 1 166 2.5E-59 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CPF12_RS03675 1356bfc89a25a88c17d6b6236311e720 323 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 119 5.2E-25 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CPF12_RS03675 1356bfc89a25a88c17d6b6236311e720 323 SUPERFAMILY SSF55347 127 290 3.27E-38 T 28-03-2018 CPF12_RS03675 1356bfc89a25a88c17d6b6236311e720 323 Gene3D G3DSA:3.30.360.10 145 322 9.9E-26 T 28-03-2018 CPF12_RS03675 1356bfc89a25a88c17d6b6236311e720 323 Gene3D G3DSA:3.40.50.720 1 144 1.3E-39 T 28-03-2018 CPF12_RS03675 1356bfc89a25a88c17d6b6236311e720 323 SUPERFAMILY SSF51735 3 153 2.56E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00200 fce9e6dbefc59c3aff4a2730db5cbf73 297 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 59 295 39.405 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CPF12_RS00200 fce9e6dbefc59c3aff4a2730db5cbf73 297 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 69 295 2.9E-82 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CPF12_RS00200 fce9e6dbefc59c3aff4a2730db5cbf73 297 PIRSF PIRSF018982 46 297 9.6E-106 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CPF12_RS08815 d88634124c86085bd6295ef6791fb98c 423 Gene3D G3DSA:3.30.565.10 278 409 1.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08815 d88634124c86085bd6295ef6791fb98c 423 SUPERFAMILY SSF55874 289 400 5.75E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08815 d88634124c86085bd6295ef6791fb98c 423 Gene3D G3DSA:1.10.287.130 209 277 6.1E-4 T 28-03-2018 CPF12_RS08815 d88634124c86085bd6295ef6791fb98c 423 Pfam PF14501 GHKL domain 321 420 2.0E-11 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CPF12_RS06005 8703fcfde7a8ffcee6863b3790b2292a 168 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 10 146 6.0E-6 T 28-03-2018 CPF12_RS06005 8703fcfde7a8ffcee6863b3790b2292a 168 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 5 163 28.712 T 28-03-2018 IPR022973 Ribosomal protein L10 CPF12_RS06005 8703fcfde7a8ffcee6863b3790b2292a 168 ProSitePatterns PS01109 Ribosomal protein L10 signature. 10 44 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS06005 8703fcfde7a8ffcee6863b3790b2292a 168 SUPERFAMILY SSF160369 7 162 2.62E-54 T 28-03-2018 CPF12_RS06005 8703fcfde7a8ffcee6863b3790b2292a 168 Pfam PF00466 Ribosomal protein L10 8 103 8.7E-29 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CPF12_RS02745 52f49f673020921515a69dfe1bfd9542 122 Pfam PF11337 Protein of unknown function (DUF3139) 5 78 1.2E-11 T 28-03-2018 IPR021486 Protein of unknown function DUF3139 CPF12_RS11630 9596cc383252174c0ad066e6b2e88e10 130 Pfam PF11068 YlqD protein 1 128 5.6E-26 T 28-03-2018 IPR021297 YlqD protein CPF12_RS00855 9a9e8a21c9bd68bfb77d857ffe720ba0 291 Pfam PF03668 P-loop ATPase protein family 7 287 4.2E-113 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CPF12_RS00855 9a9e8a21c9bd68bfb77d857ffe720ba0 291 PIRSF PIRSF005052 7 290 5.3E-108 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CPF12_RS00855 9a9e8a21c9bd68bfb77d857ffe720ba0 291 Gene3D G3DSA:3.40.50.300 1 21 0.31 T 28-03-2018 CPF12_RS00855 9a9e8a21c9bd68bfb77d857ffe720ba0 291 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 287 41.466 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CPF12_RS00855 9a9e8a21c9bd68bfb77d857ffe720ba0 291 Gene3D G3DSA:3.40.50.300 22 159 1.6E-9 T 28-03-2018 CPF12_RS00855 9a9e8a21c9bd68bfb77d857ffe720ba0 291 SUPERFAMILY SSF52540 6 159 1.09E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08940 071c0ad7503e6674058e1b4b281d0108 166 SUPERFAMILY SSF52833 4 161 9.08E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS08940 071c0ad7503e6674058e1b4b281d0108 166 Pfam PF08534 Redoxin 20 160 1.8E-22 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CPF12_RS08940 071c0ad7503e6674058e1b4b281d0108 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 4 164 35.59 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CPF12_RS08940 071c0ad7503e6674058e1b4b281d0108 166 ProSitePatterns PS01265 Tpx family signature. 84 95 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CPF12_RS08940 071c0ad7503e6674058e1b4b281d0108 166 Gene3D G3DSA:3.40.30.10 3 166 2.1E-22 T 28-03-2018 CPF12_RS09905 279bab7bc56055426b492565cc4a4653 142 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 94 6.2E-26 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CPF12_RS09905 279bab7bc56055426b492565cc4a4653 142 Gene3D G3DSA:3.90.20.10 20 141 1.3E-5 T 28-03-2018 CPF12_RS06395 838b63db1f71095797043d2a68fdc5c8 181 Gene3D G3DSA:2.40.128.20 30 179 1.8E-30 T 28-03-2018 IPR012674 Calycin CPF12_RS06395 838b63db1f71095797043d2a68fdc5c8 181 Pfam PF09148 Domain of unknown function (DUF1934) 45 160 1.2E-20 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 CPF12_RS06395 838b63db1f71095797043d2a68fdc5c8 181 SUPERFAMILY SSF50814 35 174 5.41E-22 T 28-03-2018 IPR012674 Calycin CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 Gene3D G3DSA:3.20.20.70 1 323 2.2E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 Hamap MF_01511 GMP reductase [guaC]. 2 324 62.717 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 2.3E-69 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 PIRSF PIRSF036500 1 324 1.1E-193 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 SUPERFAMILY SSF51412 3 314 1.31E-88 T 28-03-2018 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 3.7E-198 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CPF12_RS05600 989dbfccac157637dc2119d031392d79 324 SMART SM01240 3 323 1.1E-108 T 28-03-2018 CPF12_RS11015 f9cb051cce2632c5dceebe6bda5d069c 154 SUPERFAMILY SSF55729 3 142 1.86E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS11015 f9cb051cce2632c5dceebe6bda5d069c 154 Pfam PF13302 Acetyltransferase (GNAT) domain 2 135 1.7E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS11015 f9cb051cce2632c5dceebe6bda5d069c 154 Gene3D G3DSA:3.40.630.30 1 152 8.0E-19 T 28-03-2018 CPF12_RS03380 ef905a06182b5f178f8bed4152dded8f 157 Gene3D G3DSA:3.40.630.30 2 156 3.7E-7 T 28-03-2018 CPF12_RS03380 ef905a06182b5f178f8bed4152dded8f 157 SUPERFAMILY SSF55729 7 149 5.31E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS05915 0c7eec0bf3f83ad429e82d30ab25cb3b 154 PIRSF PIRSF010607 1 154 1.8E-54 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CPF12_RS05915 0c7eec0bf3f83ad429e82d30ab25cb3b 154 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 5 150 1.1E-49 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CPF12_RS07550 ba9df6a393ab410dd3778100b7957ae8 282 SUPERFAMILY SSF141986 157 281 1.44E-23 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CPF12_RS07550 ba9df6a393ab410dd3778100b7957ae8 282 Gene3D G3DSA:3.50.30.60 148 282 1.3E-21 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CPF12_RS07550 ba9df6a393ab410dd3778100b7957ae8 282 SUPERFAMILY SSF52317 2 156 9.61E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS07550 ba9df6a393ab410dd3778100b7957ae8 282 Gene3D G3DSA:3.40.50.10740 1 147 2.0E-28 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CPF12_RS07550 ba9df6a393ab410dd3778100b7957ae8 282 Pfam PF02016 LD-carboxypeptidase 8 280 2.9E-50 T 28-03-2018 IPR003507 Peptidase family S66 CPF12_RS07550 ba9df6a393ab410dd3778100b7957ae8 282 PIRSF PIRSF028757 1 282 6.1E-55 T 28-03-2018 IPR003507 Peptidase family S66 CPF12_RS02755 cc660e2ce056af613e360bd3284bfa3a 167 Pfam PF06177 QueT transporter 6 157 3.1E-28 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CPF12_RS02755 cc660e2ce056af613e360bd3284bfa3a 167 PIRSF PIRSF031501 1 165 5.2E-48 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CPF12_RS01540 0b3d277ec442275da2fcdff7248fd6ba 127 Pfam PF04134 Protein of unknown function, DUF393 5 108 1.4E-19 T 28-03-2018 IPR007263 Protein of unknown function DUF393 CPF12_RS10545 6c8aafc34c2ceda595638199ca5a79a0 89 SUPERFAMILY SSF52833 5 84 9.05E-10 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS10545 6c8aafc34c2ceda595638199ca5a79a0 89 Gene3D G3DSA:3.40.30.10 3 88 9.7E-9 T 28-03-2018 CPF12_RS10545 6c8aafc34c2ceda595638199ca5a79a0 89 Pfam PF00462 Glutaredoxin 6 61 5.1E-5 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CPF12_RS05340 8f3f67d65eee48240a5d54ba3604be89 189 Pfam PF02378 Phosphotransferase system, EIIC 21 172 9.0E-11 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS08145 00a8a956399249a75f1b5808efcbf373 220 Pfam PF04203 Sortase family 93 213 6.0E-24 T 28-03-2018 IPR005754 Sortase family CPF12_RS08145 00a8a956399249a75f1b5808efcbf373 220 Gene3D G3DSA:2.40.260.10 35 220 1.0E-34 T 28-03-2018 IPR023365 Sortase domain CPF12_RS08145 00a8a956399249a75f1b5808efcbf373 220 SUPERFAMILY SSF63817 32 213 1.83E-37 T 28-03-2018 IPR023365 Sortase domain CPF12_RS08145 00a8a956399249a75f1b5808efcbf373 220 TIGRFAM TIGR01076 sortase_fam: sortase 91 212 1.7E-19 T 28-03-2018 IPR005754 Sortase family CPF12_RS03150 0ee33a84e18a80f74d03fe4b30e24dc6 166 Pfam PF07366 SnoaL-like polyketide cyclase 34 161 7.7E-23 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CPF12_RS03150 0ee33a84e18a80f74d03fe4b30e24dc6 166 Gene3D G3DSA:3.10.450.50 24 164 2.6E-16 T 28-03-2018 CPF12_RS03150 0ee33a84e18a80f74d03fe4b30e24dc6 166 SUPERFAMILY SSF54427 31 162 3.75E-23 T 28-03-2018 IPR032710 NTF2-like domain CPF12_RS02590 072190f1cf2137d5abb4ce90ce6bdfee 262 Gene3D G3DSA:3.40.50.720 1 261 3.9E-43 T 28-03-2018 CPF12_RS02590 072190f1cf2137d5abb4ce90ce6bdfee 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 2.3E-79 T 28-03-2018 CPF12_RS02590 072190f1cf2137d5abb4ce90ce6bdfee 262 PIRSF PIRSF000094 2 262 2.3E-92 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CPF12_RS02590 072190f1cf2137d5abb4ce90ce6bdfee 262 SUPERFAMILY SSF51735 6 260 2.94E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS09425 4481c96e4eb0a0d8dde828b8fce91e48 172 SUPERFAMILY SSF54637 8 152 7.8E-41 T 28-03-2018 IPR029069 HotDog domain CPF12_RS09425 4481c96e4eb0a0d8dde828b8fce91e48 172 Pfam PF03061 Thioesterase superfamily 28 100 1.1E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CPF12_RS09425 4481c96e4eb0a0d8dde828b8fce91e48 172 Gene3D G3DSA:3.10.129.10 3 159 2.9E-41 T 28-03-2018 CPF12_RS08010 52dde7176b88304c7e8a8d72ea8e9946 382 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 70 123 2.2E-17 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CPF12_RS08010 52dde7176b88304c7e8a8d72ea8e9946 382 Gene3D G3DSA:1.10.443.10 175 368 2.2E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS08010 52dde7176b88304c7e8a8d72ea8e9946 382 SUPERFAMILY SSF56349 69 370 5.0E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CPF12_RS08010 52dde7176b88304c7e8a8d72ea8e9946 382 Gene3D G3DSA:1.10.150.130 62 174 5.2E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CPF12_RS08010 52dde7176b88304c7e8a8d72ea8e9946 382 Pfam PF14657 Arm DNA-binding domain 14 59 2.3E-11 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CPF12_RS08010 52dde7176b88304c7e8a8d72ea8e9946 382 Pfam PF00589 Phage integrase family 178 366 2.4E-26 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CPF12_RS08165 3dd856c6eccd721323452c92f73c74f9 145 Pfam PF02082 Transcriptional regulator 1 81 1.6E-21 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CPF12_RS08165 3dd856c6eccd721323452c92f73c74f9 145 Gene3D G3DSA:1.10.10.10 1 145 5.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08165 3dd856c6eccd721323452c92f73c74f9 145 SUPERFAMILY SSF46785 2 136 3.89E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06390 7ff9a374cc6c2bbaacc53da3e61271d4 61 SUPERFAMILY SSF55331 2 60 3.8E-18 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CPF12_RS06390 7ff9a374cc6c2bbaacc53da3e61271d4 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 57 6.6E-18 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CPF12_RS06390 7ff9a374cc6c2bbaacc53da3e61271d4 61 Pfam PF01361 Tautomerase enzyme 2 59 2.4E-19 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CPF12_RS06390 7ff9a374cc6c2bbaacc53da3e61271d4 61 Gene3D G3DSA:3.30.429.10 2 55 1.6E-16 T 28-03-2018 CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 Pfam PF13662 Toprim domain 4 68 2.9E-8 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 180 31.095 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 Gene3D G3DSA:3.40.1360.20 1 126 9.5E-25 T 28-03-2018 CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 SMART SM00493 4 77 5.2E-10 T 28-03-2018 IPR006171 TOPRIM domain CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 Pfam PF13331 Domain of unknown function (DUF4093) 93 178 2.6E-28 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 178 7.9E-56 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CPF12_RS05720 24b6a02647e6d0b1934d67d89f1c7ea2 187 SUPERFAMILY SSF110455 1 115 5.23E-36 T 28-03-2018 CPF12_RS11805 aa6e1248e5c4f44ae8cf0cee38b7c01b 260 SUPERFAMILY SSF102405 53 259 2.99E-29 T 28-03-2018 CPF12_RS11805 aa6e1248e5c4f44ae8cf0cee38b7c01b 260 Pfam PF02481 DNA recombination-mediator protein A 44 250 4.8E-70 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CPF12_RS11805 aa6e1248e5c4f44ae8cf0cee38b7c01b 260 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 43 258 4.2E-67 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CPF12_RS11805 aa6e1248e5c4f44ae8cf0cee38b7c01b 260 Gene3D G3DSA:3.40.50.450 84 230 2.4E-30 T 28-03-2018 CPF12_RS05415 b7106dd6e3436abcec13cab576a4039b 161 PIRSF PIRSF032285 7 160 1.0E-54 T 28-03-2018 IPR011235 MepB-like CPF12_RS05415 b7106dd6e3436abcec13cab576a4039b 161 Pfam PF08877 MepB protein 29 149 2.2E-47 T 28-03-2018 IPR011235 MepB-like CPF12_RS05335 ee7955f1c106e4fd7712f2014ad4ad4f 105 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 6 97 2.5E-9 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CPF12_RS05335 ee7955f1c106e4fd7712f2014ad4ad4f 105 SUPERFAMILY SSF48179 4 104 2.92E-14 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CPF12_RS05335 ee7955f1c106e4fd7712f2014ad4ad4f 105 Gene3D G3DSA:1.10.1040.10 3 105 4.7E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CPF12_RS00160 bb77bbf6c5fd9c170fedda84b558a5ed 366 PIRSF PIRSF019466 1 366 1.3E-143 T 28-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CPF12_RS00160 bb77bbf6c5fd9c170fedda84b558a5ed 366 Pfam PF04346 Ethanolamine utilisation protein, EutH 3 353 1.2E-151 T 28-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CPF12_RS03330 972410001efd9eee7396a5f14b12b3cf 101 Gene3D G3DSA:3.40.50.2300 1 101 6.3E-35 T 28-03-2018 CPF12_RS03330 972410001efd9eee7396a5f14b12b3cf 101 SUPERFAMILY SSF52794 1 100 1.7E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS03330 972410001efd9eee7396a5f14b12b3cf 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 93 3.4E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS02850 f94b9e51896d37307812c1e0b5541723 248 SMART SM00382 28 228 3.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS02850 f94b9e51896d37307812c1e0b5541723 248 Pfam PF00005 ABC transporter 19 162 1.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS02850 f94b9e51896d37307812c1e0b5541723 248 Gene3D G3DSA:3.40.50.300 1 234 6.8E-58 T 28-03-2018 CPF12_RS02850 f94b9e51896d37307812c1e0b5541723 248 SUPERFAMILY SSF52540 3 226 2.34E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS02850 f94b9e51896d37307812c1e0b5541723 248 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS00965 1638d27609ff8c532bb039ce6cdecbd3 168 Gene3D G3DSA:3.40.1580.10 6 162 1.2E-6 T 28-03-2018 CPF12_RS00965 1638d27609ff8c532bb039ce6cdecbd3 168 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 27 160 2.9E-6 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CPF12_RS00965 1638d27609ff8c532bb039ce6cdecbd3 168 SUPERFAMILY SSF160631 9 132 5.1E-8 T 28-03-2018 CPF12_RS11570 ca523348528e592ddf20ea382c20aed5 232 Pfam PF06182 ABC-2 family transporter protein 8 225 1.2E-19 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CPF12_RS08655 ce1c9e36541e6def6355cd81a5d6e355 318 Pfam PF01758 Sodium Bile acid symporter family 237 313 1.2E-6 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CPF12_RS08655 ce1c9e36541e6def6355cd81a5d6e355 318 Pfam PF03547 Membrane transport protein 11 167 5.8E-19 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CPF12_RS10500 c6b2c40e67dd26a94a471f1d0818f9f8 243 Pfam PF03575 Peptidase family S51 7 201 2.9E-21 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CPF12_RS10500 c6b2c40e67dd26a94a471f1d0818f9f8 243 SUPERFAMILY SSF52317 5 212 9.5E-16 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS10500 c6b2c40e67dd26a94a471f1d0818f9f8 243 Gene3D G3DSA:3.40.50.880 1 230 1.8E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS07705 58b5de430513e57ed6e23f2c2f08ac26 210 Pfam PF03413 Peptidase propeptide and YPEB domain 157 206 0.0023 T 28-03-2018 IPR025711 PepSY domain CPF12_RS07705 58b5de430513e57ed6e23f2c2f08ac26 210 Pfam PF03413 Peptidase propeptide and YPEB domain 66 120 5.7E-4 T 28-03-2018 IPR025711 PepSY domain CPF12_RS07705 58b5de430513e57ed6e23f2c2f08ac26 210 Gene3D G3DSA:3.10.450.40 151 207 1.0E-5 T 28-03-2018 CPF12_RS07705 58b5de430513e57ed6e23f2c2f08ac26 210 Gene3D G3DSA:3.10.450.40 67 135 8.6E-7 T 28-03-2018 CPF12_RS01355 8034b3cf0b599fe7a4ed7bb513c4361d 86 SUPERFAMILY SSF158221 4 40 1.44E-11 T 28-03-2018 CPF12_RS01355 8034b3cf0b599fe7a4ed7bb513c4361d 86 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 66 3.9E-26 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CPF12_RS01355 8034b3cf0b599fe7a4ed7bb513c4361d 86 Hamap MF_01103 UPF0291 protein . 1 58 13.48 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CPF12_RS01355 8034b3cf0b599fe7a4ed7bb513c4361d 86 Gene3D G3DSA:1.10.287.540 2 54 2.4E-20 T 28-03-2018 CPF12_RS05595 6862a93a52c4688b66996b1c5ba0a315 166 Pfam PF14437 MafB19-like deaminase 3 149 4.6E-43 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CPF12_RS05595 6862a93a52c4688b66996b1c5ba0a315 166 Gene3D G3DSA:3.40.140.10 1 159 2.4E-50 T 28-03-2018 CPF12_RS05595 6862a93a52c4688b66996b1c5ba0a315 166 SUPERFAMILY SSF53927 3 152 9.7E-52 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CPF12_RS05595 6862a93a52c4688b66996b1c5ba0a315 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CPF12_RS05595 6862a93a52c4688b66996b1c5ba0a315 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 149 46.265 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CPF12_RS08730 f34b574e2f1e1bcf57f8642e4ecaf47a 103 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 9.6E-47 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CPF12_RS08730 f34b574e2f1e1bcf57f8642e4ecaf47a 103 PIRSF PIRSF012508 1 100 2.5E-46 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CPF12_RS08730 f34b574e2f1e1bcf57f8642e4ecaf47a 103 Pfam PF01371 Trp repressor protein 10 94 3.5E-32 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 CPF12_RS08730 f34b574e2f1e1bcf57f8642e4ecaf47a 103 Gene3D G3DSA:1.10.1270.10 1 100 1.3E-29 T 28-03-2018 CPF12_RS08730 f34b574e2f1e1bcf57f8642e4ecaf47a 103 SUPERFAMILY SSF48295 3 94 9.94E-31 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CPF12_RS04965 5a83fdc614b1936e3f5db90871f65764 333 SUPERFAMILY SSF53474 153 226 8.36E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS04965 5a83fdc614b1936e3f5db90871f65764 333 Gene3D G3DSA:3.40.50.1820 81 287 7.6E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS12025 28042266776b76bb8e651379a80c67a3 367 Pfam PF12146 Serine aminopeptidase, S33 140 250 9.6E-8 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CPF12_RS12025 28042266776b76bb8e651379a80c67a3 367 SUPERFAMILY SSF53474 105 367 1.73E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS12025 28042266776b76bb8e651379a80c67a3 367 Gene3D G3DSA:3.40.50.1820 90 367 9.3E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS07885 58ff21caa67c830f96c0975386e2d257 293 Pfam PF00480 ROK family 7 288 1.4E-68 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS07885 58ff21caa67c830f96c0975386e2d257 293 Gene3D G3DSA:3.30.420.40 118 293 1.5E-30 T 28-03-2018 CPF12_RS07885 58ff21caa67c830f96c0975386e2d257 293 SUPERFAMILY SSF53067 8 288 5.19E-41 T 28-03-2018 CPF12_RS07885 58ff21caa67c830f96c0975386e2d257 293 ProSitePatterns PS01125 ROK family signature. 132 157 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CPF12_RS07885 58ff21caa67c830f96c0975386e2d257 293 Gene3D G3DSA:3.30.420.40 2 117 3.1E-16 T 28-03-2018 CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01998 Staphylococcal phage major tail protein signature 106 124 5.3E-10 T 28-03-2018 CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01998 Staphylococcal phage major tail protein signature 127 150 5.3E-10 T 28-03-2018 CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01998 Staphylococcal phage major tail protein signature 67 95 5.3E-10 T 28-03-2018 CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01997 Phage major tail protein 2 family signature 77 95 1.9E-34 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01997 Phage major tail protein 2 family signature 106 127 1.9E-34 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01997 Phage major tail protein 2 family signature 130 149 1.9E-34 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01997 Phage major tail protein 2 family signature 47 65 1.9E-34 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 PRINTS PR01997 Phage major tail protein 2 family signature 25 47 1.9E-34 T 28-03-2018 IPR022345 Bacteriophage 69, Orf23, major tail protein CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 TIGRFAM TIGR02126 phgtail_TP901_1: phage major tail protein, TP901-1 family 3 139 4.4E-30 T 28-03-2018 IPR011855 Phage major tail protein TP901-1 CPF12_RS01315 cb79b11374fe27a48194dcd104fde171 174 Pfam PF06199 Phage tail tube protein 5 140 2.3E-15 T 28-03-2018 IPR011855 Phage major tail protein TP901-1 CPF12_RS10630 207de4a2ac6233045ec6c75ba8321dcf 347 Pfam PF01610 Transposase 82 336 7.5E-58 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 1 481 68.941 T 28-03-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 SUPERFAMILY SSF53720 4 480 2.49E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 Gene3D G3DSA:3.40.309.10 266 459 7.5E-61 T 28-03-2018 CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 481 9.5E-178 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 Pfam PF00171 Aldehyde dehydrogenase family 15 477 6.8E-152 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 Gene3D G3DSA:3.40.605.10 1 265 1.1E-88 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS10965 0e89ac3fa9c76b8e70750cce2d48c27f 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CPF12_RS09710 774953f221dc2e1a1946fc76799597d6 236 Pfam PF07423 Protein of unknown function (DUF1510) 91 230 5.8E-31 T 28-03-2018 IPR009988 Protein of unknown function DUF1510 CPF12_RS07115 67956be11e2323a1b896fbf433f82bf6 395 SUPERFAMILY SSF53383 1 383 2.79E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS07115 67956be11e2323a1b896fbf433f82bf6 395 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 381 4.1E-124 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CPF12_RS07115 67956be11e2323a1b896fbf433f82bf6 395 Gene3D G3DSA:3.90.1150.10 269 385 1.5E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS07115 67956be11e2323a1b896fbf433f82bf6 395 Gene3D G3DSA:3.40.640.10 44 268 2.2E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS07115 67956be11e2323a1b896fbf433f82bf6 395 Pfam PF00155 Aminotransferase class I and II 52 371 4.0E-40 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS05240 ba54b85d4ec45e2d81cd7c22d22f499b 340 Pfam PF01757 Acyltransferase family 11 324 2.5E-21 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CPF12_RS03325 6f0a01c8fc08a9ff591d392a777d043d 445 PIRSF PIRSF006351 4 445 2.3E-133 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CPF12_RS03325 6f0a01c8fc08a9ff591d392a777d043d 445 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 15 437 8.0E-105 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CPF12_RS03325 6f0a01c8fc08a9ff591d392a777d043d 445 Pfam PF02378 Phosphotransferase system, EIIC 32 365 3.1E-48 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 Gene3D G3DSA:2.60.120.10 7 129 2.1E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 SMART SM00419 159 208 3.6E-4 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 Pfam PF13545 Crp-like helix-turn-helix domain 141 214 3.8E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 SUPERFAMILY SSF46785 138 216 1.27E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 ProSitePatterns PS00042 Crp-type HTH domain signature. 167 191 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 Gene3D G3DSA:1.10.10.10 130 217 4.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS04185 d1582f6efa2b41e5f87ccef9b6ffd170 218 SUPERFAMILY SSF51206 7 136 1.7E-18 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CPF12_RS04900 9ff6258f9b7b437ab86ccb19d3896a0a 299 Gene3D G3DSA:3.20.20.70 3 290 2.5E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS04900 9ff6258f9b7b437ab86ccb19d3896a0a 299 PIRSF PIRSF001359 1 283 3.3E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS04900 9ff6258f9b7b437ab86ccb19d3896a0a 299 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 282 3.1E-91 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS04900 9ff6258f9b7b437ab86ccb19d3896a0a 299 SUPERFAMILY SSF51569 4 283 1.04E-91 T 28-03-2018 CPF12_RS04900 9ff6258f9b7b437ab86ccb19d3896a0a 299 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 283 8.6E-84 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CPF12_RS10495 da8a1b16136a175ef492df5c9c98528c 141 Gene3D G3DSA:3.10.180.10 4 139 1.5E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS10495 da8a1b16136a175ef492df5c9c98528c 141 SUPERFAMILY SSF54593 5 132 6.16E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS10495 da8a1b16136a175ef492df5c9c98528c 141 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 1.2E-7 T 28-03-2018 CPF12_RS01365 32b1cacb367c831d779076fb78491633 74 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 24 72 2.6E-6 T 28-03-2018 IPR018690 Protein of unknown function DUF2187 CPF12_RS04430 376bb9d5b09212ba50f0ca7190971adc 457 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 456 6.8E-126 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CPF12_RS04430 376bb9d5b09212ba50f0ca7190971adc 457 Pfam PF03553 Na+/H+ antiporter family 159 450 5.8E-56 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CPF12_RS01750 90542683ad4ca08e9aa6c27b604d74d5 265 Pfam PF06691 Protein of unknown function (DUF1189) 5 248 4.9E-43 T 28-03-2018 IPR009574 Protein of unknown function DUF1189 CPF12_RS03735 3546a6e145186bf261087f296095d75c 223 Gene3D G3DSA:3.40.50.1240 1 223 9.4E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS03735 3546a6e145186bf261087f296095d75c 223 SUPERFAMILY SSF53254 6 221 1.83E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS03735 3546a6e145186bf261087f296095d75c 223 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 217 1.2E-37 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS03735 3546a6e145186bf261087f296095d75c 223 SMART SM00855 6 181 3.4E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS06065 71ea3b186eace838bad3e675c372ffe4 207 SUPERFAMILY SSF52166 1 206 1.7E-81 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CPF12_RS06065 71ea3b186eace838bad3e675c372ffe4 207 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 3.3E-68 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CPF12_RS06065 71ea3b186eace838bad3e675c372ffe4 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.788 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06065 71ea3b186eace838bad3e675c372ffe4 207 Gene3D G3DSA:3.40.1370.10 147 205 3.7E-14 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CPF12_RS06065 71ea3b186eace838bad3e675c372ffe4 207 Gene3D G3DSA:3.40.1370.10 2 146 2.5E-57 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CPF12_RS06065 71ea3b186eace838bad3e675c372ffe4 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 7.5E-80 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06635 afc01e1450a25341bb1e3d4db9046d51 211 SUPERFAMILY SSF53271 56 209 3.83E-14 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS06635 afc01e1450a25341bb1e3d4db9046d51 211 Gene3D G3DSA:3.40.50.2020 52 211 2.3E-16 T 28-03-2018 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 148 167 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 361 378 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 225 248 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 173 194 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 333 352 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 395 414 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 120 146 6.6E-63 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 39 419 5.9E-109 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 32 451 38.253 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS02945 01809b5d7bbc6f27b41203379878131f 452 Pfam PF01566 Natural resistance-associated macrophage protein 61 425 1.1E-122 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CPF12_RS03765 d9d5a83b0eaec05ccfd54354522d0bb0 248 Pfam PF03591 AzlC protein 31 173 9.5E-38 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CPF12_RS05405 da66b7812d8af0fdee799d81c79f0d7b 221 Gene3D G3DSA:1.10.1900.10 4 75 1.7E-9 T 28-03-2018 CPF12_RS05405 da66b7812d8af0fdee799d81c79f0d7b 221 SUPERFAMILY SSF158560 5 73 1.26E-5 T 28-03-2018 CPF12_RS05405 da66b7812d8af0fdee799d81c79f0d7b 221 Pfam PF06570 Protein of unknown function (DUF1129) 12 216 1.2E-41 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CPF12_RS05405 da66b7812d8af0fdee799d81c79f0d7b 221 PIRSF PIRSF033111 2 220 2.0E-41 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 Gene3D G3DSA:1.10.150.20 186 262 2.5E-19 T 28-03-2018 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 Gene3D G3DSA:3.30.70.270 53 126 1.9E-10 T 28-03-2018 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 Gene3D G3DSA:3.30.70.270 127 185 1.0E-8 T 28-03-2018 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 Gene3D G3DSA:3.30.1490.100 263 373 1.0E-18 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 256 365 2.1E-12 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 SUPERFAMILY SSF56672 12 249 6.49E-52 T 28-03-2018 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 SUPERFAMILY SSF100879 261 370 8.04E-9 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS10900 c8ed81802d448110bff85539b15cea06 421 Pfam PF00817 impB/mucB/samB family 17 167 3.2E-28 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CPF12_RS12245 2244dbaa6a8f8a08e3eec9f93a903fa2 145 Gene3D G3DSA:3.40.630.30 1 145 5.8E-15 T 28-03-2018 CPF12_RS12245 2244dbaa6a8f8a08e3eec9f93a903fa2 145 SUPERFAMILY SSF55729 1 139 7.85E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS12245 2244dbaa6a8f8a08e3eec9f93a903fa2 145 Pfam PF13673 Acetyltransferase (GNAT) domain 55 134 3.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS11135 5b3d8a8aa616c26fb8305bfd67b7f4f6 164 Gene3D G3DSA:3.90.79.10 1 160 6.0E-20 T 28-03-2018 CPF12_RS11135 5b3d8a8aa616c26fb8305bfd67b7f4f6 164 SUPERFAMILY SSF55811 28 159 6.91E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CPF12_RS11135 5b3d8a8aa616c26fb8305bfd67b7f4f6 164 Pfam PF00293 NUDIX domain 45 135 4.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CPF12_RS11135 5b3d8a8aa616c26fb8305bfd67b7f4f6 164 PRINTS PR00502 NUDIX hydrolase family signature 49 63 6.1E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CPF12_RS11135 5b3d8a8aa616c26fb8305bfd67b7f4f6 164 PRINTS PR00502 NUDIX hydrolase family signature 63 78 6.1E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CPF12_RS11135 5b3d8a8aa616c26fb8305bfd67b7f4f6 164 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CPF12_RS05070 aaa060e685763f7e31dfa09f96cc6648 450 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 11 432 1.1E-45 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CPF12_RS00725 dd0d9ec51a00334cce315202ea647bb3 398 SUPERFAMILY SSF53383 6 388 2.5E-87 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS00725 dd0d9ec51a00334cce315202ea647bb3 398 Gene3D G3DSA:3.40.640.10 68 284 1.6E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS00725 dd0d9ec51a00334cce315202ea647bb3 398 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 7 391 4.1E-114 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CPF12_RS00725 dd0d9ec51a00334cce315202ea647bb3 398 Gene3D G3DSA:3.90.1150.10 285 390 4.4E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS00725 dd0d9ec51a00334cce315202ea647bb3 398 Pfam PF00155 Aminotransferase class I and II 33 384 2.4E-41 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CPF12_RS06235 3b942e3c4163d289f22090cfa97f566a 164 SUPERFAMILY SSF55811 5 141 5.01E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CPF12_RS06235 3b942e3c4163d289f22090cfa97f566a 164 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CPF12_RS06235 3b942e3c4163d289f22090cfa97f566a 164 Gene3D G3DSA:3.90.79.10 4 149 6.0E-16 T 28-03-2018 CPF12_RS06235 3b942e3c4163d289f22090cfa97f566a 164 Pfam PF00293 NUDIX domain 6 129 4.3E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CPF12_RS09715 20e4a127b79b1b4e1b48173d1adb423a 232 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 231 41.645 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS09715 20e4a127b79b1b4e1b48173d1adb423a 232 Pfam PF01048 Phosphorylase superfamily 2 228 2.9E-49 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS09715 20e4a127b79b1b4e1b48173d1adb423a 232 SUPERFAMILY SSF53167 1 229 3.53E-67 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CPF12_RS09715 20e4a127b79b1b4e1b48173d1adb423a 232 Gene3D G3DSA:3.40.50.1580 1 232 3.2E-53 T 28-03-2018 CPF12_RS09715 20e4a127b79b1b4e1b48173d1adb423a 232 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 230 6.1E-75 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 SUPERFAMILY SSF51445 2 456 4.47E-157 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 Gene3D G3DSA:3.20.20.80 4 462 2.9E-147 T 28-03-2018 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 Pfam PF00232 Glycosyl hydrolase family 1 4 462 5.6E-133 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 7.2E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 385 396 7.2E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 423 7.2E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 7.2E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 361 369 7.2E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CPF12_RS04135 cf93952f6dbcaca3e2e1b0fb4becaa17 464 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 361 369 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CPF12_RS10855 7379299e83b975ee8929faeee2b2b808 446 Gene3D G3DSA:3.40.309.10 229 404 6.6E-23 T 28-03-2018 CPF12_RS10855 7379299e83b975ee8929faeee2b2b808 446 SUPERFAMILY SSF53720 10 445 1.44E-77 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS10855 7379299e83b975ee8929faeee2b2b808 446 Pfam PF00171 Aldehyde dehydrogenase family 10 270 1.3E-26 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS10855 7379299e83b975ee8929faeee2b2b808 446 Gene3D G3DSA:3.40.605.10 2 228 1.4E-32 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS00095 85bc3c6c1ba31141d88b6f489e75a73b 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 197 35.537 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CPF12_RS00095 85bc3c6c1ba31141d88b6f489e75a73b 208 Pfam PF00117 Glutamine amidotransferase class-I 4 185 3.2E-22 T 28-03-2018 IPR017926 Glutamine amidotransferase CPF12_RS00095 85bc3c6c1ba31141d88b6f489e75a73b 208 Gene3D G3DSA:3.40.50.880 1 208 1.6E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00095 85bc3c6c1ba31141d88b6f489e75a73b 208 SUPERFAMILY SSF52317 2 201 4.86E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS00095 85bc3c6c1ba31141d88b6f489e75a73b 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 196 5.5E-70 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CPF12_RS00095 85bc3c6c1ba31141d88b6f489e75a73b 208 PIRSF PIRSF000495 1 200 1.1E-72 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CPF12_RS07405 ecc032537c9349f33e81b75519b2c356 414 PIRSF PIRSF021438 1 392 2.5E-130 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CPF12_RS07405 ecc032537c9349f33e81b75519b2c356 414 Gene3D G3DSA:3.40.50.1110 63 392 1.3E-5 T 28-03-2018 CPF12_RS07405 ecc032537c9349f33e81b75519b2c356 414 Pfam PF04914 DltD protein 47 389 8.4E-119 T 28-03-2018 IPR006998 DltD CPF12_RS07405 ecc032537c9349f33e81b75519b2c356 414 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 9 389 3.3E-131 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CPF12_RS05020 765714ed4ebef53890ddf55c9df60d91 277 Pfam PF00753 Metallo-beta-lactamase superfamily 21 227 1.0E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS05020 765714ed4ebef53890ddf55c9df60d91 277 SUPERFAMILY SSF56281 18 243 2.1E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS05020 765714ed4ebef53890ddf55c9df60d91 277 Gene3D G3DSA:3.60.15.10 13 272 9.7E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS05020 765714ed4ebef53890ddf55c9df60d91 277 SMART SM00849 22 227 3.8E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CPF12_RS07295 94a82fe7dbc68fbc16718f7423a59aaf 303 Pfam PF14478 Domain of unknown function (DUF4430) 219 291 1.4E-19 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CPF12_RS08490 82af47d64941250d4260c5e4fbaa1b54 152 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 152 86.951 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CPF12_RS08490 82af47d64941250d4260c5e4fbaa1b54 152 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 2.8E-66 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CPF12_RS08490 82af47d64941250d4260c5e4fbaa1b54 152 Pfam PF03477 ATP cone domain 50 136 2.0E-19 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 Pfam PF01546 Peptidase family M20/M25/M40 67 370 5.3E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 PIRSF PIRSF005962 1 374 3.3E-108 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 Pfam PF07687 Peptidase dimerisation domain 180 269 2.0E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 SUPERFAMILY SSF53187 290 369 1.11E-68 T 28-03-2018 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 SUPERFAMILY SSF53187 4 189 1.11E-68 T 28-03-2018 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 Gene3D G3DSA:3.40.630.10 2 272 2.1E-53 T 28-03-2018 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 SUPERFAMILY SSF55031 178 281 1.1E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 59.179 T 28-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 CPF12_RS08625 d37f7f93317752610b508fb23498ea69 374 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 360 4.5E-87 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CPF12_RS01865 e48b91f06e60f735de05412752078165 96 PRINTS PR01853 Bacterial YajC preprotein translocase signature 1 21 5.4E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC CPF12_RS01865 e48b91f06e60f735de05412752078165 96 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 39 5.4E-14 T 28-03-2018 IPR003849 Preprotein translocase YajC CPF12_RS01865 e48b91f06e60f735de05412752078165 96 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 1 80 4.5E-26 T 28-03-2018 IPR003849 Preprotein translocase YajC CPF12_RS01865 e48b91f06e60f735de05412752078165 96 SMART SM01323 1 80 1.7E-35 T 28-03-2018 IPR003849 Preprotein translocase YajC CPF12_RS01865 e48b91f06e60f735de05412752078165 96 Pfam PF02699 Preprotein translocase subunit 3 77 6.9E-28 T 28-03-2018 IPR003849 Preprotein translocase YajC CPF12_RS10560 9449c606fa18ebbae5e88e6f99a35d7c 85 SUPERFAMILY SSF110836 3 83 8.11E-17 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CPF12_RS10560 9449c606fa18ebbae5e88e6f99a35d7c 85 SMART SM00932 4 85 3.5E-6 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CPF12_RS10560 9449c606fa18ebbae5e88e6f99a35d7c 85 Gene3D G3DSA:3.30.1370.70 2 85 1.9E-14 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CPF12_RS10560 9449c606fa18ebbae5e88e6f99a35d7c 85 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 5 84 7.3E-15 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CPF12_RS04610 f46f3b01c2b37c1650c1c84454fce8b1 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 327 8.3E-99 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CPF12_RS04610 f46f3b01c2b37c1650c1c84454fce8b1 332 SUPERFAMILY SSF51679 1 327 6.54E-70 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS04610 f46f3b01c2b37c1650c1c84454fce8b1 332 Gene3D G3DSA:3.20.20.30 1 332 1.4E-59 T 28-03-2018 CPF12_RS04610 f46f3b01c2b37c1650c1c84454fce8b1 332 Pfam PF00296 Luciferase-like monooxygenase 1 299 2.9E-32 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CPF12_RS04870 077219ac6931dbdfecde462c6de51cf2 114 Pfam PF00746 LPXTG cell wall anchor motif 73 106 3.4E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS04870 077219ac6931dbdfecde462c6de51cf2 114 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 75 109 9.5E-6 T 28-03-2018 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 Gene3D G3DSA:1.20.5.40 112 131 2.8E-8 T 28-03-2018 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 SUPERFAMILY SSF53041 1 142 4.97E-34 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 Gene3D G3DSA:1.10.10.60 132 195 1.2E-4 T 28-03-2018 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 Pfam PF00239 Resolvase, N terminal domain 4 142 3.3E-32 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 Gene3D G3DSA:3.40.50.1390 3 111 1.4E-27 T 28-03-2018 CPF12_RS03515 c5fb431a3e59a15a003306b8f78c0310 207 SMART SM00857 3 142 1.5E-37 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CPF12_RS09735 1efa587d137a9fe23770123ea8329288 366 Gene3D G3DSA:3.40.50.300 57 225 1.9E-26 T 28-03-2018 CPF12_RS09735 1efa587d137a9fe23770123ea8329288 366 SUPERFAMILY SSF52540 69 280 2.95E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS09735 1efa587d137a9fe23770123ea8329288 366 Pfam PF01926 50S ribosome-binding GTPase 164 230 4.7E-14 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CPF12_RS09735 1efa587d137a9fe23770123ea8329288 366 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 7 365 1.5E-149 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CPF12_RS12395 b1a29ef6207523bac5b643a52def3eb4 188 Gene3D G3DSA:1.20.1440.20 17 187 8.3E-60 T 28-03-2018 CPF12_RS12395 b1a29ef6207523bac5b643a52def3eb4 188 SUPERFAMILY SSF140478 29 175 5.23E-55 T 28-03-2018 IPR023353 LemA-like domain CPF12_RS12395 b1a29ef6207523bac5b643a52def3eb4 188 Pfam PF04011 LemA family 9 186 7.2E-71 T 28-03-2018 IPR007156 LemA CPF12_RS09120 bda19f21dec57d4456f20001bd9b07ed 490 Pfam PF00324 Amino acid permease 22 471 1.8E-132 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CPF12_RS09120 bda19f21dec57d4456f20001bd9b07ed 490 PIRSF PIRSF006060 4 486 1.1E-83 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CPF12_RS09120 bda19f21dec57d4456f20001bd9b07ed 490 ProSitePatterns PS00218 Amino acid permeases signature. 47 78 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CPF12_RS02460 2807b7f052fd111f8f7a0815ce4d19e1 1088 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 668 934 7.1E-15 T 28-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain CPF12_RS02460 2807b7f052fd111f8f7a0815ce4d19e1 1088 SUPERFAMILY SSF48208 550 1041 3.97E-32 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CPF12_RS02460 2807b7f052fd111f8f7a0815ce4d19e1 1088 Gene3D G3DSA:2.70.98.40 3 251 7.3E-10 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CPF12_RS02460 2807b7f052fd111f8f7a0815ce4d19e1 1088 Gene3D G3DSA:1.50.10.10 579 937 3.5E-29 T 28-03-2018 CPF12_RS10445 a8c8ed128221cb631a29d2b9a0550fa8 76 SUPERFAMILY SSF52833 5 71 1.91E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CPF12_RS10445 a8c8ed128221cb631a29d2b9a0550fa8 76 Pfam PF00462 Glutaredoxin 5 59 1.9E-11 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CPF12_RS10445 a8c8ed128221cb631a29d2b9a0550fa8 76 Gene3D G3DSA:3.40.30.10 2 75 3.6E-12 T 28-03-2018 CPF12_RS10485 28f4c44f186f15ba1e496809d37f6fbd 233 Pfam PF13731 WxL domain surface cell wall-binding 32 230 4.9E-43 T 28-03-2018 IPR027994 WxL domain CPF12_RS09430 8552772dc1295476bc63910a4c9f1517 190 PIRSF PIRSF037778 2 188 9.4E-50 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CPF12_RS09430 8552772dc1295476bc63910a4c9f1517 190 Pfam PF12822 ECF transporter, substrate-specific component 7 175 6.2E-25 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CPF12_RS08395 82eed2aeb3c1bf8e4673fba531f9b830 164 Pfam PF00583 Acetyltransferase (GNAT) family 38 142 3.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS08395 82eed2aeb3c1bf8e4673fba531f9b830 164 Gene3D G3DSA:3.40.630.30 1 164 1.6E-23 T 28-03-2018 CPF12_RS08395 82eed2aeb3c1bf8e4673fba531f9b830 164 SUPERFAMILY SSF55729 1 151 2.44E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS12020 a564e35ea6a37f90878cda3a4fbf0562 235 Gene3D G3DSA:3.20.20.70 5 233 5.9E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS12020 a564e35ea6a37f90878cda3a4fbf0562 235 SUPERFAMILY SSF51569 6 231 1.22E-46 T 28-03-2018 CPF12_RS12020 a564e35ea6a37f90878cda3a4fbf0562 235 TIGRFAM TIGR02134 transald_staph: transaldolase 5 235 2.0E-108 T 28-03-2018 IPR011861 Transaldolase, Staphylococcus-type CPF12_RS12020 a564e35ea6a37f90878cda3a4fbf0562 235 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 7 211 1.1E-36 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CPF12_RS00460 406643f9d783172de4fe2971a643c50b 303 Gene3D G3DSA:3.40.50.720 1 133 1.7E-34 T 28-03-2018 CPF12_RS00460 406643f9d783172de4fe2971a643c50b 303 SUPERFAMILY SSF51735 3 137 8.01E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS00460 406643f9d783172de4fe2971a643c50b 303 Gene3D G3DSA:3.30.360.10 134 303 2.7E-19 T 28-03-2018 CPF12_RS00460 406643f9d783172de4fe2971a643c50b 303 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 3.0E-21 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CPF12_RS00460 406643f9d783172de4fe2971a643c50b 303 SUPERFAMILY SSF55347 123 261 6.0E-35 T 28-03-2018 CPF12_RS09315 effee6f5f38171b5bd357e5ce6843719 147 Pfam PF09424 Yqey-like protein 6 146 5.7E-54 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CPF12_RS09315 effee6f5f38171b5bd357e5ce6843719 147 SUPERFAMILY SSF89095 1 147 1.52E-42 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CPF12_RS09315 effee6f5f38171b5bd357e5ce6843719 147 Gene3D G3DSA:1.10.10.410 91 147 4.2E-20 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CPF12_RS09315 effee6f5f38171b5bd357e5ce6843719 147 Gene3D G3DSA:1.10.1510.10 1 90 2.7E-30 T 28-03-2018 CPF12_RS11650 a47c5d0862dfa17774f1e8818a2a6e88 328 Pfam PF13280 WYL domain 151 319 2.4E-10 T 28-03-2018 IPR026881 WYL domain CPF12_RS04565 7f88a852567a865fefa15e9b0bf40699 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 120 3.2E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS04565 7f88a852567a865fefa15e9b0bf40699 126 Gene3D G3DSA:3.10.180.10 1 125 2.6E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS04565 7f88a852567a865fefa15e9b0bf40699 126 SUPERFAMILY SSF54593 1 122 2.82E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS04045 0e4e7096ab7149b04c8b3427939723c7 281 Pfam PF13731 WxL domain surface cell wall-binding 31 269 1.7E-59 T 28-03-2018 IPR027994 WxL domain CPF12_RS03450 3e502a3a262cad17606e67244275ad6f 320 Gene3D G3DSA:3.40.250.10 112 221 7.0E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS03450 3e502a3a262cad17606e67244275ad6f 320 Pfam PF12368 Rhodanase C-terminal 225 291 5.6E-14 T 28-03-2018 IPR022111 Rhodanase, C-terminal CPF12_RS03450 3e502a3a262cad17606e67244275ad6f 320 Pfam PF00581 Rhodanese-like domain 121 213 1.8E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS03450 3e502a3a262cad17606e67244275ad6f 320 SMART SM00450 118 219 7.2E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS03450 3e502a3a262cad17606e67244275ad6f 320 SUPERFAMILY SSF52821 91 246 1.17E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CPF12_RS03450 3e502a3a262cad17606e67244275ad6f 320 Hamap MF_00469 UPF0176 protein YceA [yceA]. 6 270 37.426 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 CPF12_RS11165 c74e95282c0df1e56ce6dec9c264a909 191 Gene3D G3DSA:3.40.50.150 2 191 2.3E-17 T 28-03-2018 CPF12_RS11165 c74e95282c0df1e56ce6dec9c264a909 191 Pfam PF06962 Putative rRNA methylase 48 189 3.3E-45 T 28-03-2018 IPR010719 Putative rRNA methylase CPF12_RS11165 c74e95282c0df1e56ce6dec9c264a909 191 SUPERFAMILY SSF53335 12 147 1.44E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS05695 19af7924a0e0a8b180fcf4dc39467040 89 SUPERFAMILY SSF82771 5 74 2.09E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS05695 19af7924a0e0a8b180fcf4dc39467040 89 Gene3D G3DSA:3.40.1440.10 2 86 1.9E-4 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS05695 19af7924a0e0a8b180fcf4dc39467040 89 Pfam PF01541 GIY-YIG catalytic domain 5 75 2.8E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS05970 791328b3afdb229f165b4fa7b400d520 173 Pfam PF05991 YacP-like NYN domain 5 167 4.6E-52 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CPF12_RS05635 8bfb2a0fa30ba00091f67c73e16b5a00 144 Gene3D G3DSA:1.10.3100.10 2 113 9.6E-20 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS05635 8bfb2a0fa30ba00091f67c73e16b5a00 144 Pfam PF01381 Helix-turn-helix 7 61 5.0E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05635 8bfb2a0fa30ba00091f67c73e16b5a00 144 SMART SM00530 6 61 1.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05635 8bfb2a0fa30ba00091f67c73e16b5a00 144 SUPERFAMILY SSF47413 2 64 6.91E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 Pfam PF09182 Bacterial purine repressor, N-terminal 4 72 2.5E-30 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 270 5.3E-120 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 Gene3D G3DSA:1.10.10.10 1 73 3.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 Gene3D G3DSA:3.40.50.2020 74 273 1.8E-32 T 28-03-2018 CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 SUPERFAMILY SSF46785 2 72 1.41E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 72 6.0E-23 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 SUPERFAMILY SSF53271 85 257 2.84E-38 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CPF12_RS05740 1ae3102659824d28e0d4d3f23605746f 277 Pfam PF00156 Phosphoribosyl transferase domain 112 253 4.2E-23 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CPF12_RS00405 61ef8a8578b3c47bde22b2d29a28180f 111 Gene3D G3DSA:1.10.10.10 10 107 6.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00405 61ef8a8578b3c47bde22b2d29a28180f 111 Pfam PF01638 HxlR-like helix-turn-helix 13 100 3.3E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CPF12_RS00405 61ef8a8578b3c47bde22b2d29a28180f 111 SUPERFAMILY SSF46785 5 99 9.93E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 SUPERFAMILY SSF52518 2 204 1.12E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 Gene3D G3DSA:3.40.50.920 195 324 7.3E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 SMART SM00861 4 179 9.2E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 SUPERFAMILY SSF52922 189 324 1.83E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 Gene3D G3DSA:3.40.50.970 1 194 6.0E-66 T 28-03-2018 CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 2.0E-43 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CPF12_RS02200 4f8df44149bc3e1f8cf0e355cbd3e350 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 5.2E-38 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CPF12_RS04205 64c68170307f5b0213a41f8147aac533 416 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 414 4.9E-192 T 28-03-2018 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 CPF12_RS04205 64c68170307f5b0213a41f8147aac533 416 Gene3D G3DSA:1.20.1250.20 199 415 1.5E-24 T 28-03-2018 CPF12_RS04205 64c68170307f5b0213a41f8147aac533 416 Pfam PF03825 Nucleoside H+ symporter 1 407 1.1E-166 T 28-03-2018 CPF12_RS04205 64c68170307f5b0213a41f8147aac533 416 Gene3D G3DSA:1.20.1250.20 6 191 4.7E-11 T 28-03-2018 CPF12_RS04205 64c68170307f5b0213a41f8147aac533 416 SUPERFAMILY SSF103473 9 407 4.58E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS11720 c4e661f9285d14f35efc82cd2e3e7a6b 122 Pfam PF03733 Inner membrane component domain 4 54 8.7E-18 T 28-03-2018 IPR005185 Inner membrane component domain CPF12_RS11720 c4e661f9285d14f35efc82cd2e3e7a6b 122 Pfam PF03733 Inner membrane component domain 66 115 4.9E-18 T 28-03-2018 IPR005185 Inner membrane component domain CPF12_RS11720 c4e661f9285d14f35efc82cd2e3e7a6b 122 PIRSF PIRSF028777 1 122 7.4E-44 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 CPF12_RS05105 e4a5fc2836402464e4a6374aac2abd7a 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CPF12_RS05105 e4a5fc2836402464e4a6374aac2abd7a 89 Gene3D G3DSA:4.10.830.10 1 89 4.9E-35 T 28-03-2018 CPF12_RS05105 e4a5fc2836402464e4a6374aac2abd7a 89 SUPERFAMILY SSF57716 2 89 9.03E-31 T 28-03-2018 CPF12_RS05105 e4a5fc2836402464e4a6374aac2abd7a 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 4.8E-29 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CPF12_RS05105 e4a5fc2836402464e4a6374aac2abd7a 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 24.862 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 Gene3D G3DSA:3.40.50.300 256 462 1.1E-26 T 28-03-2018 CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 Pfam PF04851 Type III restriction enzyme, res subunit 261 447 1.7E-38 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 13 200 1.2E-20 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 SUPERFAMILY SSF52540 630 759 1.65E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 SUPERFAMILY SSF52540 282 337 1.65E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 Gene3D G3DSA:3.40.50.300 527 761 5.4E-4 T 28-03-2018 CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 114 747 2.4E-93 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 SMART SM00487 259 474 3.4E-18 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CPF12_RS08270 f97af85e3a84a1848918a549f9935b5c 1023 SUPERFAMILY SSF52540 239 450 1.36E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS05685 4a4c01ee8cabb22b38efeeabef9f5122 122 PIRSF PIRSF021439 1 120 3.9E-39 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CPF12_RS05685 4a4c01ee8cabb22b38efeeabef9f5122 122 Pfam PF06156 Initiation control protein YabA 1 114 2.2E-34 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CPF12_RS05685 4a4c01ee8cabb22b38efeeabef9f5122 122 Hamap MF_01159 Initiation-control protein YabA. 1 119 23.0 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CPF12_RS00030 bde371d72d611a4e3d74bd2ffbd4abe4 409 SUPERFAMILY SSF63411 6 198 1.33E-34 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS00030 bde371d72d611a4e3d74bd2ffbd4abe4 409 Gene3D G3DSA:3.30.830.10 226 402 5.2E-6 T 28-03-2018 CPF12_RS00030 bde371d72d611a4e3d74bd2ffbd4abe4 409 Pfam PF00675 Insulinase (Peptidase family M16) 15 132 1.3E-15 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CPF12_RS00030 bde371d72d611a4e3d74bd2ffbd4abe4 409 Gene3D G3DSA:3.30.830.10 5 213 4.1E-40 T 28-03-2018 CPF12_RS00030 bde371d72d611a4e3d74bd2ffbd4abe4 409 Pfam PF05193 Peptidase M16 inactive domain 163 312 1.3E-5 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CPF12_RS00030 bde371d72d611a4e3d74bd2ffbd4abe4 409 SUPERFAMILY SSF63411 234 396 1.66E-5 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CPF12_RS08865 f3f06fd91c23eb66a189b7d126f0b25d 201 Pfam PF02397 Bacterial sugar transferase 6 179 1.2E-57 T 28-03-2018 IPR003362 Bacterial sugar transferase CPF12_RS11860 76bb3ef248d2e0f02a271c6122646ec7 119 Gene3D G3DSA:1.10.1660.10 3 104 1.9E-22 T 28-03-2018 CPF12_RS11860 76bb3ef248d2e0f02a271c6122646ec7 119 SUPERFAMILY SSF46955 13 95 5.13E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain CPF12_RS11860 76bb3ef248d2e0f02a271c6122646ec7 119 Pfam PF13411 MerR HTH family regulatory protein 14 78 1.0E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS11860 76bb3ef248d2e0f02a271c6122646ec7 119 SMART SM00422 13 81 7.1E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CPF12_RS07690 d350724a4d6ee242fa459c63df7992ea 463 PIRSF PIRSF006603 3 456 1.2E-74 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS07690 d350724a4d6ee242fa459c63df7992ea 463 Pfam PF01554 MatE 253 408 1.2E-15 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS07690 d350724a4d6ee242fa459c63df7992ea 463 Pfam PF01554 MatE 29 190 1.7E-15 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CPF12_RS05030 79dee135f0d8fd88f3413b3d4079a9e8 426 Pfam PF07435 YycH protein 9 422 6.5E-52 T 28-03-2018 IPR009996 Regulatory protein YycH CPF12_RS04280 ea8b2db88f42326e3be2640db668de86 256 Gene3D G3DSA:1.10.530.10 27 178 4.1E-36 T 28-03-2018 CPF12_RS04280 ea8b2db88f42326e3be2640db668de86 256 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 47 174 1.5E-22 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS04280 ea8b2db88f42326e3be2640db668de86 256 SMART SM00047 27 179 2.8E-33 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 Pfam PF00575 S1 RNA binding domain 628 709 2.4E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 ProSitePatterns PS01175 Ribonuclease II family signature. 548 572 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SUPERFAMILY SSF50249 128 228 4.29E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 Hamap MF_01895 Ribonuclease R [rnr]. 26 711 57.378 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SUPERFAMILY SSF50249 211 628 1.4E-142 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SUPERFAMILY SSF50249 55 137 1.02E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SMART SM00955 251 581 6.3E-175 T 28-03-2018 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 Gene3D G3DSA:2.40.50.140 628 712 3.4E-22 T 28-03-2018 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SMART SM00357 74 135 1.6E-8 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SMART SM00316 629 711 1.3E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 Pfam PF00773 RNB domain 251 579 2.7E-112 T 28-03-2018 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 Pfam PF08206 Ribonuclease B OB domain 75 134 3.6E-21 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 TIGRFAM TIGR02063 RNase_R: ribonuclease R 6 711 2.1E-274 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 SUPERFAMILY SSF50249 629 710 1.12E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CPF12_RS07580 9330a91ae8868e722677f7c7fc0a047b 788 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 62 711 3.7E-225 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CPF12_RS00850 4ad670de1f1ca2f0c1ca700ad1735933 433 Pfam PF01610 Transposase 168 422 1.6E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS00850 4ad670de1f1ca2f0c1ca700ad1735933 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS04795 366df59951e5fde7a226d8d679dfd62d 439 Pfam PF13641 Glycosyltransferase like family 2 54 281 2.5E-23 T 28-03-2018 CPF12_RS04795 366df59951e5fde7a226d8d679dfd62d 439 SUPERFAMILY SSF53448 54 293 8.72E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS04795 366df59951e5fde7a226d8d679dfd62d 439 SUPERFAMILY SSF53448 323 368 8.72E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS04795 366df59951e5fde7a226d8d679dfd62d 439 Gene3D G3DSA:3.90.550.10 53 306 8.2E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS08535 a1c326723937c3491d4e00fc6a26a38e 195 Gene3D G3DSA:1.10.10.60 1 60 1.8E-14 T 28-03-2018 CPF12_RS08535 a1c326723937c3491d4e00fc6a26a38e 195 SUPERFAMILY SSF48498 98 192 5.11E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CPF12_RS08535 a1c326723937c3491d4e00fc6a26a38e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 59 7.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CPF12_RS08535 a1c326723937c3491d4e00fc6a26a38e 195 Gene3D G3DSA:1.10.357.10 61 192 7.7E-6 T 28-03-2018 CPF12_RS08535 a1c326723937c3491d4e00fc6a26a38e 195 SUPERFAMILY SSF46689 6 71 9.23E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS07650 0f1d7e3c4475f8c072de25e963ffa557 262 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 1 229 8.0E-20 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS07650 0f1d7e3c4475f8c072de25e963ffa557 262 SUPERFAMILY SSF56784 1 260 9.8E-61 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07650 0f1d7e3c4475f8c072de25e963ffa557 262 ProSitePatterns PS01229 Hypothetical cof family signature 2. 210 232 - T 28-03-2018 CPF12_RS07650 0f1d7e3c4475f8c072de25e963ffa557 262 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 1 256 8.1E-59 T 28-03-2018 IPR000150 Cof family GO:0016787 CPF12_RS07650 0f1d7e3c4475f8c072de25e963ffa557 262 Pfam PF08282 haloacid dehalogenase-like hydrolase 2 256 1.5E-54 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS07650 0f1d7e3c4475f8c072de25e963ffa557 262 Gene3D G3DSA:3.40.50.1000 1 262 1.6E-34 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS11920 b1b46152919ff77b130005da2090526e 647 SUPERFAMILY SSF52540 5 208 3.31E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS11920 b1b46152919ff77b130005da2090526e 647 SMART SM00382 25 207 3.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS11920 b1b46152919ff77b130005da2090526e 647 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS11920 b1b46152919ff77b130005da2090526e 647 Gene3D G3DSA:3.40.50.300 1 243 6.7E-54 T 28-03-2018 CPF12_RS11920 b1b46152919ff77b130005da2090526e 647 Pfam PF00005 ABC transporter 28 161 1.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS11230 cc81b492b90ebcce7c84ecf673483b71 300 Gene3D G3DSA:1.10.4100.10 68 252 4.8E-28 T 28-03-2018 CPF12_RS11230 cc81b492b90ebcce7c84ecf673483b71 300 Pfam PF03313 Serine dehydratase alpha chain 16 276 7.6E-74 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CPF12_RS11230 cc81b492b90ebcce7c84ecf673483b71 300 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 5 291 3.4E-100 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CPF12_RS02440 7ca652f0018363450cbf33d967a9d177 383 Gene3D G3DSA:3.40.50.2000 195 367 4.1E-38 T 28-03-2018 CPF12_RS02440 7ca652f0018363450cbf33d967a9d177 383 SUPERFAMILY SSF53756 4 380 6.67E-59 T 28-03-2018 CPF12_RS02440 7ca652f0018363450cbf33d967a9d177 383 Pfam PF00534 Glycosyl transferases group 1 205 358 6.6E-37 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CPF12_RS04160 d0d6bd15178c9478e4b474c20ccb88f9 229 Gene3D G3DSA:1.10.260.40 1 186 4.6E-21 T 28-03-2018 CPF12_RS04160 d0d6bd15178c9478e4b474c20ccb88f9 229 Pfam PF01381 Helix-turn-helix 7 61 1.5E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS04160 d0d6bd15178c9478e4b474c20ccb88f9 229 SMART SM00530 6 61 5.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS04160 d0d6bd15178c9478e4b474c20ccb88f9 229 SUPERFAMILY SSF47413 1 67 6.17E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS07035 898963f1fcc05a752018825f207fb0f7 165 SUPERFAMILY SSF55729 1 163 1.72E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS07035 898963f1fcc05a752018825f207fb0f7 165 Gene3D G3DSA:3.40.630.30 1 165 1.7E-30 T 28-03-2018 CPF12_RS07035 898963f1fcc05a752018825f207fb0f7 165 Pfam PF13420 Acetyltransferase (GNAT) domain 2 153 4.3E-23 T 28-03-2018 CPF12_RS01465 adaf52bb6950a5fff5b884568f3212b1 264 Gene3D G3DSA:3.90.1200.10 29 260 3.7E-15 T 28-03-2018 CPF12_RS01465 adaf52bb6950a5fff5b884568f3212b1 264 SUPERFAMILY SSF56112 6 229 1.66E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CPF12_RS01465 adaf52bb6950a5fff5b884568f3212b1 264 Pfam PF01636 Phosphotransferase enzyme family 14 213 9.5E-17 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CPF12_RS03155 4d6071e51e4c66ea545e9bcbae6bde35 383 SUPERFAMILY SSF103473 5 372 6.54E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS03155 4d6071e51e4c66ea545e9bcbae6bde35 383 Gene3D G3DSA:1.20.1250.20 2 175 1.0E-16 T 28-03-2018 CPF12_RS03155 4d6071e51e4c66ea545e9bcbae6bde35 383 Gene3D G3DSA:1.20.1250.20 178 380 6.7E-14 T 28-03-2018 CPF12_RS03155 4d6071e51e4c66ea545e9bcbae6bde35 383 Pfam PF07690 Major Facilitator Superfamily 12 298 1.1E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS09055 023a2603b5a71f932d160ec74256c728 148 Pfam PF13581 Histidine kinase-like ATPase domain 13 143 3.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09055 023a2603b5a71f932d160ec74256c728 148 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 4 148 4.7E-52 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CPF12_RS09055 023a2603b5a71f932d160ec74256c728 148 Gene3D G3DSA:3.30.565.10 5 143 7.3E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS09055 023a2603b5a71f932d160ec74256c728 148 SUPERFAMILY SSF55874 29 136 1.7E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS03050 9d066830e4aa7c6d1cafce26d233b122 284 SMART SM00382 31 218 4.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS03050 9d066830e4aa7c6d1cafce26d233b122 284 SUPERFAMILY SSF52540 6 223 2.05E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS03050 9d066830e4aa7c6d1cafce26d233b122 284 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS03050 9d066830e4aa7c6d1cafce26d233b122 284 Pfam PF00005 ABC transporter 22 162 1.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS03050 9d066830e4aa7c6d1cafce26d233b122 284 Gene3D G3DSA:3.40.50.300 3 270 1.6E-67 T 28-03-2018 CPF12_RS05690 53c8b6afb8ab650275ab3e1356b618fd 244 Gene3D G3DSA:3.40.50.150 6 243 5.2E-35 T 28-03-2018 CPF12_RS05690 53c8b6afb8ab650275ab3e1356b618fd 244 Pfam PF05175 Methyltransferase small domain 16 125 4.4E-10 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CPF12_RS05690 53c8b6afb8ab650275ab3e1356b618fd 244 SUPERFAMILY SSF53335 14 199 1.92E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS04695 0d7c81597ff67ef0e7fccab70a6fa06d 365 Pfam PF08713 DNA alkylation repair enzyme 120 217 4.5E-5 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CPF12_RS04695 0d7c81597ff67ef0e7fccab70a6fa06d 365 Gene3D G3DSA:1.25.40.290 128 240 4.3E-18 T 28-03-2018 CPF12_RS04695 0d7c81597ff67ef0e7fccab70a6fa06d 365 SUPERFAMILY SSF48371 28 237 2.09E-34 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CPF12_RS09110 1528a17aa1c1106c2a13795ddf7f1ec4 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 16.226 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CPF12_RS09110 1528a17aa1c1106c2a13795ddf7f1ec4 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 111 1.6E-21 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CPF12_RS05060 80a0963b4540dd9cc2f4fcb0090bc6fd 318 Gene3D G3DSA:1.10.3470.10 1 318 3.0E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS05060 80a0963b4540dd9cc2f4fcb0090bc6fd 318 SUPERFAMILY SSF81345 3 311 1.7E-69 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS05060 80a0963b4540dd9cc2f4fcb0090bc6fd 318 Pfam PF01032 FecCD transport family 10 311 4.5E-69 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS03900 be31b6cff145077476db755175368180 399 Pfam PF05684 Protein of unknown function (DUF819) 5 167 8.2E-6 T 28-03-2018 IPR008537 Protein of unknown function DUF819 CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 SMART SM00418 13 96 3.7E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 8.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 8.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 45 8.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 8.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 SUPERFAMILY SSF46785 9 86 3.67E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 Gene3D G3DSA:1.10.10.10 2 85 2.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01765 ea292482e4265da8fb712104d240049a 117 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 3.1E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CPF12_RS11265 3c9e8b72f9ab143736e5c4b6c493fc7d 193 SUPERFAMILY SSF52317 1 191 7.99E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11265 3c9e8b72f9ab143736e5c4b6c493fc7d 193 Gene3D G3DSA:3.40.50.880 1 193 2.3E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11265 3c9e8b72f9ab143736e5c4b6c493fc7d 193 Pfam PF01965 DJ-1/PfpI family 3 176 1.6E-30 T 28-03-2018 IPR002818 DJ-1/PfpI CPF12_RS04100 5f7e1ce745be5371c3f04fd32c3308e4 334 Pfam PF01032 FecCD transport family 21 332 2.1E-82 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS04100 5f7e1ce745be5371c3f04fd32c3308e4 334 SUPERFAMILY SSF81345 4 332 5.62E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS04100 5f7e1ce745be5371c3f04fd32c3308e4 334 Gene3D G3DSA:1.10.3470.10 5 334 7.6E-57 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS02070 326d6e305f5f7531113fe15c8f546145 389 Pfam PF05636 HIGH Nucleotidyl Transferase 1 376 7.0E-119 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CPF12_RS02070 326d6e305f5f7531113fe15c8f546145 389 Gene3D G3DSA:3.40.50.620 1 237 7.5E-48 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS02070 326d6e305f5f7531113fe15c8f546145 389 Hamap MF_01539 UPF0348 protein . 2 388 35.274 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CPF12_RS02070 326d6e305f5f7531113fe15c8f546145 389 SUPERFAMILY SSF52374 9 146 3.15E-21 T 28-03-2018 CPF12_RS02070 326d6e305f5f7531113fe15c8f546145 389 SUPERFAMILY SSF52374 200 242 3.15E-21 T 28-03-2018 CPF12_RS08925 73c0732ea9465f3c89bfef1244dc8bb6 582 Gene3D G3DSA:1.20.120.330 63 243 1.7E-4 T 28-03-2018 CPF12_RS08925 73c0732ea9465f3c89bfef1244dc8bb6 582 Pfam PF06160 Septation ring formation regulator, EzrA 19 574 4.9E-122 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CPF12_RS11945 5bf96a56aa192a056825110bfc97d253 329 SUPERFAMILY SSF53474 38 169 9.1E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS11945 5bf96a56aa192a056825110bfc97d253 329 SUPERFAMILY SSF53474 224 294 9.1E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS11945 5bf96a56aa192a056825110bfc97d253 329 Gene3D G3DSA:3.40.50.1820 22 303 2.0E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS11945 5bf96a56aa192a056825110bfc97d253 329 Pfam PF00326 Prolyl oligopeptidase family 114 299 5.8E-11 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 153 174 1.0E-46 T 28-03-2018 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 116 1.8E-11 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 Pfam PF00361 Proton-conducting membrane transporter 129 427 2.9E-73 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 796 2.5E-281 T 28-03-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 CPF12_RS07100 ca2ea2e22a9a72daf4122de67221edf9 801 Pfam PF13244 Domain of unknown function (DUF4040) 635 698 2.6E-18 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CPF12_RS07080 60e3de1fb52ba00b3ebe329436fa205e 159 PIRSF PIRSF019239 1 159 3.4E-40 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CPF12_RS07080 60e3de1fb52ba00b3ebe329436fa205e 159 Pfam PF01899 Na+/H+ ion antiporter subunit 10 156 3.2E-37 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CPF12_RS05190 975839077badd4898fb69e485ab8d9fd 197 SUPERFAMILY SSF50475 2 193 4.66E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CPF12_RS05190 975839077badd4898fb69e485ab8d9fd 197 SMART SM00903 20 170 5.7E-21 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CPF12_RS05190 975839077badd4898fb69e485ab8d9fd 197 Gene3D G3DSA:2.30.110.10 3 194 2.3E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CPF12_RS05190 975839077badd4898fb69e485ab8d9fd 197 Pfam PF01613 Flavin reductase like domain 23 169 6.3E-22 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CPF12_RS04990 c3243ae8cd3ef046de6aed8949bdd2dd 487 Pfam PF02687 FtsX-like permease family 349 481 2.5E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 Gene3D G3DSA:1.10.60.10 68 117 1.3E-20 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 SMART SM00529 24 122 7.3E-40 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 127 3.7E-19 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 2.4E-25 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 SUPERFAMILY SSF47979 63 131 2.35E-19 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 SUPERFAMILY SSF46785 3 62 3.67E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 136 38.67 T 28-03-2018 IPR022897 Transcription regulator MntR CPF12_RS10540 e0f5accd97227bf4c62a3cf05bb2fb58 136 Gene3D G3DSA:1.10.10.10 1 67 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10765 5dd0c22b119daa4998d7e99bf71ef049 93 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 80 1.2E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS10765 5dd0c22b119daa4998d7e99bf71ef049 93 Gene3D G3DSA:3.40.50.2300 1 92 4.4E-16 T 28-03-2018 CPF12_RS10765 5dd0c22b119daa4998d7e99bf71ef049 93 SUPERFAMILY SSF52794 1 88 5.36E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CPF12_RS03780 da8606f3d89a45c3d9c04c562c8a4cce 121 Pfam PF07457 Protein of unknown function (DUF1516) 7 118 2.3E-23 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CPF12_RS03780 da8606f3d89a45c3d9c04c562c8a4cce 121 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 9 103 1.0E-9 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CPF12_RS03625 e6177e9ad7dec3121b592ffaef983c01 393 Pfam PF07690 Major Facilitator Superfamily 10 331 5.5E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS03625 e6177e9ad7dec3121b592ffaef983c01 393 SUPERFAMILY SSF103473 4 383 4.58E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS03625 e6177e9ad7dec3121b592ffaef983c01 393 Gene3D G3DSA:1.20.1250.20 1 192 1.4E-22 T 28-03-2018 CPF12_RS03625 e6177e9ad7dec3121b592ffaef983c01 393 Gene3D G3DSA:1.20.1250.20 193 376 8.0E-15 T 28-03-2018 CPF12_RS09300 f54a0e8650ebc6f715a8237d291e206f 313 SUPERFAMILY SSF53335 74 311 2.69E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS09300 f54a0e8650ebc6f715a8237d291e206f 313 PIRSF PIRSF000401 1 313 8.2E-106 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CPF12_RS09300 f54a0e8650ebc6f715a8237d291e206f 313 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 35.703 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CPF12_RS09300 f54a0e8650ebc6f715a8237d291e206f 313 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 304 1.4E-84 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CPF12_RS09300 f54a0e8650ebc6f715a8237d291e206f 313 Gene3D G3DSA:3.40.50.150 116 313 6.8E-45 T 28-03-2018 CPF12_RS09300 f54a0e8650ebc6f715a8237d291e206f 313 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 311 5.7E-98 T 28-03-2018 CPF12_RS06965 7835590c089223928fda07052329ce65 160 SUPERFAMILY SSF55826 7 157 1.83E-35 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CPF12_RS06965 7835590c089223928fda07052329ce65 160 Pfam PF04073 Aminoacyl-tRNA editing domain 28 147 7.2E-22 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CPF12_RS06965 7835590c089223928fda07052329ce65 160 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 7 157 1.3E-54 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CPF12_RS06965 7835590c089223928fda07052329ce65 160 Gene3D G3DSA:3.90.960.10 1 159 1.5E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CPF12_RS06965 7835590c089223928fda07052329ce65 160 PIRSF PIRSF006181 2 160 2.6E-58 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CPF12_RS03255 341f09bf791d5df3091cb59f8a6e8dc8 182 Gene3D G3DSA:3.40.50.880 1 180 1.9E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS03255 341f09bf791d5df3091cb59f8a6e8dc8 182 Pfam PF01965 DJ-1/PfpI family 4 164 3.9E-43 T 28-03-2018 IPR002818 DJ-1/PfpI CPF12_RS03255 341f09bf791d5df3091cb59f8a6e8dc8 182 SUPERFAMILY SSF52317 1 179 1.8E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS03255 341f09bf791d5df3091cb59f8a6e8dc8 182 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 4 176 9.5E-52 T 28-03-2018 IPR006287 Protein DJ-1 CPF12_RS10595 40105a13b17bec57037a78dfc2d1c06a 279 SUPERFAMILY SSF82549 3 279 1.39E-75 T 28-03-2018 CPF12_RS10595 40105a13b17bec57037a78dfc2d1c06a 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 278 1.0E-74 T 28-03-2018 IPR003797 DegV CPF12_RS10595 40105a13b17bec57037a78dfc2d1c06a 279 Gene3D G3DSA:3.40.50.10170 1 153 1.1E-43 T 28-03-2018 CPF12_RS10595 40105a13b17bec57037a78dfc2d1c06a 279 Gene3D G3DSA:3.30.1180.10 154 278 1.4E-24 T 28-03-2018 CPF12_RS10595 40105a13b17bec57037a78dfc2d1c06a 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 276 4.3E-82 T 28-03-2018 IPR003797 DegV CPF12_RS00950 3603ac1bee4c1e03e31085e23d6bde56 349 Gene3D G3DSA:1.10.3470.10 1 341 1.2E-42 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS00950 3603ac1bee4c1e03e31085e23d6bde56 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 329 8.8E-45 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CPF12_RS02280 284153ed9775e5f4be4a740bdacc2852 157 Gene3D G3DSA:3.40.630.30 1 157 1.4E-34 T 28-03-2018 CPF12_RS02280 284153ed9775e5f4be4a740bdacc2852 157 SUPERFAMILY SSF55729 5 148 5.16E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS02280 284153ed9775e5f4be4a740bdacc2852 157 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 2.9E-40 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CPF12_RS02280 284153ed9775e5f4be4a740bdacc2852 157 Pfam PF00583 Acetyltransferase (GNAT) family 17 125 1.5E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 SUPERFAMILY SSF52317 289 531 3.82E-82 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 Gene3D G3DSA:3.40.50.300 1 286 3.6E-135 T 28-03-2018 CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 Pfam PF06418 CTP synthase N-terminus 3 267 1.1E-130 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 Hamap MF_01227 CTP synthase [pyrG]. 2 533 52.741 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 Pfam PF00117 Glutamine amidotransferase class-I 302 527 5.6E-58 T 28-03-2018 IPR017926 Glutamine amidotransferase CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 Gene3D G3DSA:3.40.50.880 287 533 1.7E-72 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 SUPERFAMILY SSF52540 2 270 2.92E-126 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS06410 bd7b71c7dafd2c032565f7404cacaf25 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 528 1.1E-259 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CPF12_RS02520 aa7f442bb57dce2e36371d9053a8f5d7 275 SUPERFAMILY SSF88713 74 256 7.05E-38 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CPF12_RS02520 aa7f442bb57dce2e36371d9053a8f5d7 275 Gene3D G3DSA:3.20.20.370 21 270 4.5E-44 T 28-03-2018 CPF12_RS02520 aa7f442bb57dce2e36371d9053a8f5d7 275 Pfam PF01522 Polysaccharide deacetylase 113 235 4.7E-29 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CPF12_RS07900 5ab7e753b2fad259a505d01fc579061a 572 SUPERFAMILY SSF48208 266 448 2.84E-12 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CPF12_RS07900 5ab7e753b2fad259a505d01fc579061a 572 Gene3D G3DSA:1.50.10.20 174 509 4.6E-18 T 28-03-2018 CPF12_RS03760 330dc58b600e0ba0a499ffeb02392e0d 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 105 1.5E-21 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CPF12_RS10375 e3f1712235d94ec885e741ee235a0ccf 358 Pfam PF02687 FtsX-like permease family 268 352 1.5E-5 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS11610 7d2824d0b109cfab7f71bee4c26c6f5e 135 Pfam PF07883 Cupin domain 48 108 1.3E-6 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CPF12_RS11610 7d2824d0b109cfab7f71bee4c26c6f5e 135 Gene3D G3DSA:2.60.120.10 8 135 6.0E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS11610 7d2824d0b109cfab7f71bee4c26c6f5e 135 SUPERFAMILY SSF51182 12 133 1.6E-24 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS00130 0530d24e86d7415ff2cb38053ae0f9ab 71 Pfam PF13619 KTSC domain 8 63 1.3E-14 T 28-03-2018 IPR025309 KTSC domain CPF12_RS01015 091edf49416d8e8571f1e1e76dfa1473 246 Pfam PF00218 Indole-3-glycerol phosphate synthase 28 243 3.2E-78 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CPF12_RS01015 091edf49416d8e8571f1e1e76dfa1473 246 Gene3D G3DSA:3.20.20.70 3 245 4.6E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CPF12_RS01015 091edf49416d8e8571f1e1e76dfa1473 246 SUPERFAMILY SSF51366 1 244 1.98E-72 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CPF12_RS01015 091edf49416d8e8571f1e1e76dfa1473 246 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 44 62 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CPF12_RS04115 1659fe8ab53eb9097747d67cb4e280ed 310 Pfam PF01497 Periplasmic binding protein 63 283 3.6E-19 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CPF12_RS04115 1659fe8ab53eb9097747d67cb4e280ed 310 SUPERFAMILY SSF53807 40 298 2.59E-42 T 28-03-2018 CPF12_RS04115 1659fe8ab53eb9097747d67cb4e280ed 310 Gene3D G3DSA:3.40.50.1980 25 146 5.0E-20 T 28-03-2018 CPF12_RS04115 1659fe8ab53eb9097747d67cb4e280ed 310 Gene3D G3DSA:3.40.50.1980 147 307 1.3E-21 T 28-03-2018 CPF12_RS04520 e0dacbb086a40e5fcc592f4cb4fde9de 34 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 2 34 1.5E-11 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CPF12_RS03435 daa757c4d996a95a44cc820781222b1f 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 1.5E-82 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CPF12_RS03435 daa757c4d996a95a44cc820781222b1f 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 262 7.0E-75 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS03435 daa757c4d996a95a44cc820781222b1f 270 Gene3D G3DSA:3.40.1190.20 1 270 4.4E-55 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS03435 daa757c4d996a95a44cc820781222b1f 270 SUPERFAMILY SSF53613 1 263 5.46E-70 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS05110 578c06e3363c0420e08a6c256c30b9a0 62 Pfam PF01783 Ribosomal L32p protein family 2 55 1.4E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05110 578c06e3363c0420e08a6c256c30b9a0 62 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.169 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS05110 578c06e3363c0420e08a6c256c30b9a0 62 SUPERFAMILY SSF57829 1 54 1.4E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CPF12_RS05110 578c06e3363c0420e08a6c256c30b9a0 62 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.3E-20 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS01660 4d2ba9e64a047428281ac9f1413848de 163 Pfam PF13079 Protein of unknown function (DUF3916) 31 105 1.7E-4 T 28-03-2018 IPR025075 Protein of unknown function DUF3916 CPF12_RS03060 7a131bf7900460151c58f99664ff0779 424 SUPERFAMILY SSF52777 201 350 2.67E-7 T 28-03-2018 CPF12_RS03060 7a131bf7900460151c58f99664ff0779 424 Gene3D G3DSA:3.30.1330.40 209 310 0.0021 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CPF12_RS03340 5f61f5afb8de38065b5af70d45a5afcc 243 Gene3D G3DSA:3.40.50.10490 105 239 2.0E-18 T 28-03-2018 CPF12_RS03340 5f61f5afb8de38065b5af70d45a5afcc 243 Gene3D G3DSA:1.10.10.10 3 104 4.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03340 5f61f5afb8de38065b5af70d45a5afcc 243 SUPERFAMILY SSF46689 6 72 1.97E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CPF12_RS03340 5f61f5afb8de38065b5af70d45a5afcc 243 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 70 6.3E-16 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CPF12_RS03340 5f61f5afb8de38065b5af70d45a5afcc 243 SUPERFAMILY SSF53697 80 230 8.75E-31 T 28-03-2018 CPF12_RS03340 5f61f5afb8de38065b5af70d45a5afcc 243 Pfam PF01380 SIS domain 108 206 5.3E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 Gene3D G3DSA:3.90.470.20 1 117 1.0E-30 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 22.829 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 90 2.3E-17 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 SUPERFAMILY SSF56214 1 115 1.28E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 116 1.7E-25 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 1.0E-31 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CPF12_RS09025 29b2cf046609d428885bd2191c651388 117 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 115 4.0E-28 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CPF12_RS03910 6fa8ccadd8ed81cf12dad75305913c00 287 SUPERFAMILY SSF81345 9 260 4.84E-43 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS03910 6fa8ccadd8ed81cf12dad75305913c00 287 Pfam PF00950 ABC 3 transport family 10 264 1.7E-84 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CPF12_RS03910 6fa8ccadd8ed81cf12dad75305913c00 287 Gene3D G3DSA:1.10.3470.10 7 272 4.9E-35 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS08895 451203284708d1f25d4fe8b69b0122a3 228 SUPERFAMILY SSF52540 46 222 1.03E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08895 451203284708d1f25d4fe8b69b0122a3 228 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 27 224 1.4E-56 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CPF12_RS08895 451203284708d1f25d4fe8b69b0122a3 228 Gene3D G3DSA:3.40.50.300 7 227 5.2E-39 T 28-03-2018 CPF12_RS08895 451203284708d1f25d4fe8b69b0122a3 228 Pfam PF13614 AAA domain 54 201 4.7E-16 T 28-03-2018 IPR025669 AAA domain CPF12_RS05205 8ef8825fe37e827d79b85b0b8775d34b 446 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 420 2.0E-140 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CPF12_RS05205 8ef8825fe37e827d79b85b0b8775d34b 446 Pfam PF05525 Branched-chain amino acid transport protein 10 433 9.1E-158 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CPF12_RS08380 79a5314fb05ee8284db55cb088b9a3be 76 Pfam PF06569 Protein of unknown function (DUF1128) 3 71 1.0E-21 T 28-03-2018 IPR009507 Protein of unknown function UPF0435 CPF12_RS00265 f55bfcfb20bc9ab813c06abe2e9341eb 341 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 66 312 9.3E-45 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CPF12_RS00265 f55bfcfb20bc9ab813c06abe2e9341eb 341 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 24 319 29.576 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CPF12_RS00265 f55bfcfb20bc9ab813c06abe2e9341eb 341 SUPERFAMILY SSF52540 99 319 2.36E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00265 f55bfcfb20bc9ab813c06abe2e9341eb 341 Gene3D G3DSA:1.10.40.50 257 324 4.4E-21 T 28-03-2018 CPF12_RS00265 f55bfcfb20bc9ab813c06abe2e9341eb 341 Pfam PF03193 RsgA GTPase 83 256 2.7E-44 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CPF12_RS00265 f55bfcfb20bc9ab813c06abe2e9341eb 341 Gene3D G3DSA:3.40.50.300 97 255 6.7E-27 T 28-03-2018 CPF12_RS04415 38a672c29840fd08d060d5ea82a6fc5f 551 SUPERFAMILY SSF161098 294 547 1.96E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04415 38a672c29840fd08d060d5ea82a6fc5f 551 SUPERFAMILY SSF161098 10 272 1.68E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04415 38a672c29840fd08d060d5ea82a6fc5f 551 Gene3D G3DSA:1.10.3720.10 296 549 4.0E-36 T 28-03-2018 CPF12_RS04415 38a672c29840fd08d060d5ea82a6fc5f 551 Gene3D G3DSA:1.10.3720.10 10 279 9.6E-40 T 28-03-2018 CPF12_RS04415 38a672c29840fd08d060d5ea82a6fc5f 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 276 1.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04415 38a672c29840fd08d060d5ea82a6fc5f 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 365 538 3.6E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04055 45810d4f05fc8f1d5254175153c615b3 259 Pfam PF13731 WxL domain surface cell wall-binding 34 255 1.0E-60 T 28-03-2018 IPR027994 WxL domain CPF12_RS00430 1323005d29f61927aceedc3f19525b09 516 Pfam PF12773 Double zinc ribbon 4 67 1.4E-10 T 28-03-2018 IPR025874 Double zinc ribbon CPF12_RS00430 1323005d29f61927aceedc3f19525b09 516 Gene3D G3DSA:2.20.28.20 46 75 0.11 T 28-03-2018 CPF12_RS00430 1323005d29f61927aceedc3f19525b09 516 Gene3D G3DSA:2.20.28.20 3 30 1.1E-5 T 28-03-2018 CPF12_RS12380 28260f0b90ee932e01030bf155f97afe 171 Pfam PF13302 Acetyltransferase (GNAT) domain 6 144 7.1E-29 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS12380 28260f0b90ee932e01030bf155f97afe 171 SUPERFAMILY SSF55729 1 155 4.29E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS12380 28260f0b90ee932e01030bf155f97afe 171 Gene3D G3DSA:3.40.630.30 1 168 3.3E-22 T 28-03-2018 CPF12_RS07500 4398e6d5f4445fb8da35e4cab8d01350 265 Pfam PF00005 ABC transporter 20 166 5.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07500 4398e6d5f4445fb8da35e4cab8d01350 265 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07500 4398e6d5f4445fb8da35e4cab8d01350 265 SUPERFAMILY SSF52540 4 229 5.74E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07500 4398e6d5f4445fb8da35e4cab8d01350 265 SMART SM00382 28 216 4.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07500 4398e6d5f4445fb8da35e4cab8d01350 265 Gene3D G3DSA:3.40.50.300 2 246 7.5E-59 T 28-03-2018 CPF12_RS10300 ae1980238ac899eb2f4abeac8e5d8063 433 Pfam PF01610 Transposase 168 422 2.0E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS10300 ae1980238ac899eb2f4abeac8e5d8063 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS02865 a3b038123b296793ca379a3825017979 184 Pfam PF11667 Putative zincin peptidase 58 162 2.2E-16 T 28-03-2018 IPR021683 Putative zincin peptidase CPF12_RS00425 f4bf725732517c9dc469234fdc03a919 309 Pfam PF13240 zinc-ribbon domain 3 23 3.5E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CPF12_RS07820 1bc8408faf98edb4f795804ab124fb6f 262 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07820 1bc8408faf98edb4f795804ab124fb6f 262 SUPERFAMILY SSF52540 6 233 1.18E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07820 1bc8408faf98edb4f795804ab124fb6f 262 Gene3D G3DSA:3.40.50.300 3 250 7.4E-43 T 28-03-2018 CPF12_RS07820 1bc8408faf98edb4f795804ab124fb6f 262 Pfam PF00005 ABC transporter 21 173 2.0E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07820 1bc8408faf98edb4f795804ab124fb6f 262 SMART SM00382 30 225 1.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07820 1bc8408faf98edb4f795804ab124fb6f 262 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 244 1.8E-111 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CPF12_RS00905 058b75f831e2419c18e96944026857ac 341 SUPERFAMILY SSF74650 7 335 1.51E-91 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CPF12_RS00905 058b75f831e2419c18e96944026857ac 341 PIRSF PIRSF005096 1 338 1.1E-94 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CPF12_RS00905 058b75f831e2419c18e96944026857ac 341 Gene3D G3DSA:2.70.98.10 7 341 3.6E-85 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CPF12_RS00905 058b75f831e2419c18e96944026857ac 341 Pfam PF01263 Aldose 1-epimerase 19 334 5.1E-69 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CPF12_RS00905 058b75f831e2419c18e96944026857ac 341 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 171 180 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CPF12_RS12435 3310cd375e912c5ff4f4f9f2caade6df 333 SUPERFAMILY SSF56235 4 333 1.93E-103 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CPF12_RS12435 3310cd375e912c5ff4f4f9f2caade6df 333 Gene3D G3DSA:3.60.60.10 4 333 3.9E-87 T 28-03-2018 CPF12_RS12435 3310cd375e912c5ff4f4f9f2caade6df 333 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 4 317 1.1E-94 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CPF12_RS00210 c9b876beab2db6e9574c74d38dae9d3e 476 Pfam PF06277 Ethanolamine utilisation protein EutA 3 476 1.9E-194 T 28-03-2018 IPR009377 Ethanolamine utilisation EutA CPF12_RS00210 c9b876beab2db6e9574c74d38dae9d3e 476 SUPERFAMILY SSF53067 5 180 1.51E-9 T 28-03-2018 CPF12_RS00210 c9b876beab2db6e9574c74d38dae9d3e 476 PIRSF PIRSF012293 1 476 1.4E-192 T 28-03-2018 IPR009377 Ethanolamine utilisation EutA CPF12_RS00210 c9b876beab2db6e9574c74d38dae9d3e 476 Gene3D G3DSA:3.30.420.40 5 182 3.7E-14 T 28-03-2018 CPF12_RS01260 3cbbc3e9663a948345a7adfd75c925cc 91 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 7 86 7.4E-22 T 28-03-2018 IPR006485 Bacteriophage holin CPF12_RS01260 3cbbc3e9663a948345a7adfd75c925cc 91 Pfam PF04531 Bacteriophage holin 7 86 1.4E-27 T 28-03-2018 IPR006485 Bacteriophage holin CPF12_RS00390 8677a9cf22bed3af03374c27f97981e5 119 Gene3D G3DSA:3.40.1440.10 18 118 2.9E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS00390 8677a9cf22bed3af03374c27f97981e5 119 SUPERFAMILY SSF82771 19 119 1.96E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS12405 f2f0d5d8355b4f8280ae6f2bbb968db7 157 PIRSF PIRSF021441 1 156 5.7E-55 T 28-03-2018 IPR031306 CcdC protein CPF12_RS12405 f2f0d5d8355b4f8280ae6f2bbb968db7 157 Pfam PF07301 Protein of unknown function (DUF1453) 6 145 1.1E-45 T 28-03-2018 IPR009916 Protein of unknown function DUF1453 CPF12_RS01210 0fbe9c6430d3fbe11182b3778d84e715 144 Gene3D G3DSA:1.10.10.10 5 142 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS01210 0fbe9c6430d3fbe11182b3778d84e715 144 TIGRFAM TIGR01636 phage_rinA: phage transcriptional regulator, RinA family 8 143 2.4E-22 T 28-03-2018 IPR006523 Transcription activator RinA CPF12_RS02025 0ee1b7530113c5fbeb8b66303bfa311c 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CPF12_RS02025 0ee1b7530113c5fbeb8b66303bfa311c 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 18 320 1.0E-101 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CPF12_RS02025 0ee1b7530113c5fbeb8b66303bfa311c 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 323 22.649 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CPF12_RS02025 0ee1b7530113c5fbeb8b66303bfa311c 324 Pfam PF00953 Glycosyl transferase family 4 81 248 1.4E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CPF12_RS04290 a91f104423a6a9de1a500a43fe5988b1 384 SUPERFAMILY SSF53756 148 376 2.04E-11 T 28-03-2018 CPF12_RS04290 a91f104423a6a9de1a500a43fe5988b1 384 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 18 377 4.7E-107 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CPF12_RS01330 803ade79889a26d7f9a89a7de933b831 65 Pfam PF01381 Helix-turn-helix 4 59 1.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS01330 803ade79889a26d7f9a89a7de933b831 65 SMART SM00530 3 59 3.2E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS01330 803ade79889a26d7f9a89a7de933b831 65 SUPERFAMILY SSF47413 4 62 7.6E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS01330 803ade79889a26d7f9a89a7de933b831 65 Gene3D G3DSA:1.10.3100.10 2 65 1.2E-13 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS00785 8ee9fef7d5a3deea88e899142cb3cf8d 155 SMART SM00347 26 129 2.9E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00785 8ee9fef7d5a3deea88e899142cb3cf8d 155 Gene3D G3DSA:1.10.10.10 1 132 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00785 8ee9fef7d5a3deea88e899142cb3cf8d 155 SUPERFAMILY SSF46785 7 148 3.13E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00785 8ee9fef7d5a3deea88e899142cb3cf8d 155 Pfam PF01047 MarR family 36 91 1.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS09585 e6b670d34085f871aead8ea385a52572 424 Pfam PF12698 ABC-2 family transporter protein 21 415 2.5E-40 T 28-03-2018 CPF12_RS09585 e6b670d34085f871aead8ea385a52572 424 Gene3D G3DSA:3.40.1710.10 44 244 8.6E-19 T 28-03-2018 CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 SUPERFAMILY SSF55874 174 333 1.44E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 Gene3D G3DSA:3.30.565.10 148 333 1.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 227 333 8.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 334 8.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 263 277 8.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 315 8.0E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CPF12_RS08980 22d47cf0a210483757a59113656a29ca 348 SMART SM00387 226 337 7.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CPF12_RS11760 3f01890403bdd0cc570f66d2291b1655 269 Gene3D G3DSA:3.40.50.1000 1 268 6.6E-30 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS11760 3f01890403bdd0cc570f66d2291b1655 269 SUPERFAMILY SSF56784 1 262 1.26E-51 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS11760 3f01890403bdd0cc570f66d2291b1655 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 1.6E-17 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CPF12_RS11760 3f01890403bdd0cc570f66d2291b1655 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 258 1.9E-38 T 28-03-2018 IPR023214 HAD-like domain CPF12_RS12260 260e4edb95ffc06bed21ab184da6e3df 265 Gene3D G3DSA:1.10.1900.10 6 83 1.3E-18 T 28-03-2018 CPF12_RS12260 260e4edb95ffc06bed21ab184da6e3df 265 SUPERFAMILY SSF158560 1 93 3.79E-15 T 28-03-2018 CPF12_RS02750 15f4c6c3ceb8080f815eedcc7be62f2b 132 Gene3D G3DSA:3.40.190.10 1 128 9.0E-4 T 28-03-2018 CPF12_RS02750 15f4c6c3ceb8080f815eedcc7be62f2b 132 Pfam PF14478 Domain of unknown function (DUF4430) 67 130 5.2E-14 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CPF12_RS04670 79fac63b7f0bb9dccbc69d7dcbea8211 127 Gene3D G3DSA:3.10.180.10 1 127 1.3E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS04670 79fac63b7f0bb9dccbc69d7dcbea8211 127 SUPERFAMILY SSF54593 1 126 1.32E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CPF12_RS04670 79fac63b7f0bb9dccbc69d7dcbea8211 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 125 2.9E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CPF12_RS11155 b39acf091245bc52a79248a9bb7e7e35 129 PIRSF PIRSF021389 3 129 3.0E-19 T 28-03-2018 IPR016789 Uncharacterised conserved protein UCP021389 CPF12_RS11155 b39acf091245bc52a79248a9bb7e7e35 129 Pfam PF10049 Protein of unknown function (DUF2283) 9 57 1.5E-7 T 28-03-2018 IPR019270 Protein of unknown function DUF2283 CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 SUPERFAMILY SSF46785 152 220 1.66E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 Gene3D G3DSA:1.10.10.10 134 223 3.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 SMART SM00100 15 133 4.6E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 Pfam PF00027 Cyclic nucleotide-binding domain 34 115 2.5E-19 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 SUPERFAMILY SSF51206 20 142 6.02E-26 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 Pfam PF13545 Crp-like helix-turn-helix domain 154 217 1.2E-6 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CPF12_RS11590 814e7b8546927328033bb5f1e07eadf2 223 Gene3D G3DSA:2.60.120.10 10 133 1.6E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS01215 6a587c8fcd1e9d688c68429e999c1465 150 Pfam PF05866 Endodeoxyribonuclease RusA 7 134 1.5E-30 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CPF12_RS01215 6a587c8fcd1e9d688c68429e999c1465 150 Gene3D G3DSA:3.30.1330.70 1 140 6.3E-24 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CPF12_RS01215 6a587c8fcd1e9d688c68429e999c1465 150 SUPERFAMILY SSF103084 2 135 1.96E-20 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 1.8E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 1.8E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 1.8E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 1.8E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 1.8E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 127 388 4.0E-16 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 SUPERFAMILY SSF50621 274 431 2.09E-53 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 2.7E-153 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 Gene3D G3DSA:2.40.37.10 283 436 1.3E-43 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.7E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.7E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.7E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.7E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 296 1.2E-68 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 SUPERFAMILY SSF51419 30 299 5.38E-80 T 28-03-2018 IPR029066 PLP-binding barrel CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 40.962 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CPF12_RS09395 7770d63fe4f12aa1db15a05449866e21 436 Gene3D G3DSA:3.20.20.10 39 282 2.3E-61 T 28-03-2018 IPR029066 PLP-binding barrel CPF12_RS06730 cc1f5be4a8a6518a4d4d43140e8da524 214 SUPERFAMILY SSF109604 3 188 3.14E-33 T 28-03-2018 CPF12_RS06730 cc1f5be4a8a6518a4d4d43140e8da524 214 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 79 187 2.0E-6 T 28-03-2018 CPF12_RS06730 cc1f5be4a8a6518a4d4d43140e8da524 214 Pfam PF12917 HD containing hydrolase-like enzyme 1 207 1.7E-94 T 28-03-2018 IPR027366 HD containing hydrolase-like enzyme CPF12_RS06730 cc1f5be4a8a6518a4d4d43140e8da524 214 Gene3D G3DSA:1.10.3210.10 1 214 1.9E-43 T 28-03-2018 CPF12_RS02635 121a52f628329a8c51e57b1b6ade5e40 303 Gene3D G3DSA:3.30.420.150 118 299 2.2E-33 T 28-03-2018 CPF12_RS02635 121a52f628329a8c51e57b1b6ade5e40 303 Gene3D G3DSA:3.30.420.40 2 117 7.8E-41 T 28-03-2018 CPF12_RS02635 121a52f628329a8c51e57b1b6ade5e40 303 Pfam PF02541 Ppx/GppA phosphatase family 22 301 9.0E-59 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CPF12_RS02635 121a52f628329a8c51e57b1b6ade5e40 303 SUPERFAMILY SSF53067 3 125 1.81E-35 T 28-03-2018 CPF12_RS02635 121a52f628329a8c51e57b1b6ade5e40 303 SUPERFAMILY SSF53067 130 301 5.77E-34 T 28-03-2018 CPF12_RS10865 68e614341059acdae9c35cf688aae235 207 PIRSF PIRSF031644 1 207 3.2E-61 T 28-03-2018 IPR008319 Uncharacterised conserved protein UCP031644 CPF12_RS10865 68e614341059acdae9c35cf688aae235 207 Gene3D G3DSA:3.20.80.10 1 206 1.5E-55 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CPF12_RS10865 68e614341059acdae9c35cf688aae235 207 Pfam PF06445 GyrI-like small molecule binding domain 19 204 1.5E-14 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CPF12_RS07005 41639bf731d61390b4830039722bc6ce 235 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS07005 41639bf731d61390b4830039722bc6ce 235 SMART SM00382 28 215 8.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS07005 41639bf731d61390b4830039722bc6ce 235 SUPERFAMILY SSF52540 3 213 3.76E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS07005 41639bf731d61390b4830039722bc6ce 235 Pfam PF00005 ABC transporter 19 165 5.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS07005 41639bf731d61390b4830039722bc6ce 235 Gene3D G3DSA:3.40.50.300 2 219 1.6E-52 T 28-03-2018 CPF12_RS05505 b862f196335751cfa371be62cd6692a7 153 Pfam PF01381 Helix-turn-helix 6 60 1.1E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05505 b862f196335751cfa371be62cd6692a7 153 SUPERFAMILY SSF47413 2 67 3.75E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS05505 b862f196335751cfa371be62cd6692a7 153 SMART SM00530 5 60 2.8E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS05505 b862f196335751cfa371be62cd6692a7 153 Gene3D G3DSA:1.10.3100.10 1 89 1.1E-22 T 28-03-2018 IPR027910 YdiL-like domain CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 SUPERFAMILY SSF52172 3 186 1.02E-38 T 28-03-2018 IPR011006 CheY-like superfamily CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 SMART SM00862 148 223 4.6E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 Gene3D G3DSA:1.10.10.10 123 225 1.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 Gene3D G3DSA:3.40.50.2300 2 122 2.4E-33 T 28-03-2018 CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 Pfam PF00072 Response regulator receiver domain 5 114 8.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.2E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CPF12_RS10670 a52cc40d8b2b2bfacdfacc103087a04d 228 SMART SM00448 3 113 1.2E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CPF12_RS07010 679000416535c36221883041a7c66081 275 Pfam PF00950 ABC 3 transport family 6 262 1.4E-68 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CPF12_RS07010 679000416535c36221883041a7c66081 275 SUPERFAMILY SSF81345 2 260 2.22E-35 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS07010 679000416535c36221883041a7c66081 275 Gene3D G3DSA:1.10.3470.10 2 272 5.9E-25 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS01515 0b33586326f28416afb99d5da9d81f07 325 Pfam PF07136 Protein of unknown function (DUF1385) 55 295 1.2E-77 T 28-03-2018 IPR010787 Protein of unknown function DUF1385 CPF12_RS01515 0b33586326f28416afb99d5da9d81f07 325 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 55 289 6.0E-81 T 28-03-2018 IPR010787 Protein of unknown function DUF1385 CPF12_RS09970 50ed9164c1c7f6324ff70fe99aa80958 330 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 154 2.9E-23 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CPF12_RS02410 37242879a47bf726dfc8b5de0b2aed8a 206 Pfam PF01944 Stage II sporulation protein M 30 197 1.4E-13 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CPF12_RS04230 cad6085c0e3ebe53b89fe9bdd9da481a 165 Gene3D G3DSA:2.60.120.10 1 160 7.8E-59 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CPF12_RS04230 cad6085c0e3ebe53b89fe9bdd9da481a 165 Pfam PF06172 Cupin superfamily (DUF985) 5 138 1.8E-44 T 28-03-2018 IPR009327 Cupin domain of unknown function DUF985 CPF12_RS04230 cad6085c0e3ebe53b89fe9bdd9da481a 165 SUPERFAMILY SSF51182 2 159 3.26E-55 T 28-03-2018 IPR011051 RmlC-like cupin domain CPF12_RS11250 0b21ced7a3c7b073e34da2733b27c966 139 SUPERFAMILY SSF46785 7 135 1.27E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11250 0b21ced7a3c7b073e34da2733b27c966 139 Pfam PF01475 Ferric uptake regulator family 15 130 7.0E-28 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CPF12_RS11250 0b21ced7a3c7b073e34da2733b27c966 139 Gene3D G3DSA:1.10.10.10 8 93 7.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS07315 ed9ef54781d079ed54b449ca41a19c83 233 PIRSF PIRSF037395 1 231 8.1E-63 T 28-03-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 CPF12_RS07315 ed9ef54781d079ed54b449ca41a19c83 233 Pfam PF12822 ECF transporter, substrate-specific component 57 208 1.1E-11 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CPF12_RS03840 82703cf62ac75ff22041610c11cf5be2 128 PIRSF PIRSF031568 1 127 1.9E-23 T 28-03-2018 IPR009530 Protein of unknown function DUF1149 CPF12_RS03840 82703cf62ac75ff22041610c11cf5be2 128 Gene3D G3DSA:3.10.420.10 1 125 3.2E-32 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CPF12_RS03840 82703cf62ac75ff22041610c11cf5be2 128 Pfam PF06619 Protein of unknown function (DUF1149) 1 125 2.4E-26 T 28-03-2018 IPR009530 Protein of unknown function DUF1149 CPF12_RS03840 82703cf62ac75ff22041610c11cf5be2 128 SUPERFAMILY SSF54611 1 125 3.6E-21 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CPF12_RS07075 4e0e68eda458b5e21910bd84d52ce422 96 PIRSF PIRSF028784 1 93 3.8E-26 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CPF12_RS07075 4e0e68eda458b5e21910bd84d52ce422 96 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 82 5.1E-18 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CPF12_RS08585 3a703b1c95cda4535949757c92d581d2 249 Pfam PF06738 Putative threonine/serine exporter 8 246 1.2E-70 T 28-03-2018 IPR010619 Putative threonine/serine exporter CPF12_RS04705 6eb7f01f2b4cc92e69c1bbe14e4174a2 165 Pfam PF04525 LURP-one-related 5 147 1.9E-16 T 28-03-2018 IPR007612 LURP1-related protein domain CPF12_RS04705 6eb7f01f2b4cc92e69c1bbe14e4174a2 165 SUPERFAMILY SSF54518 3 152 5.49E-36 T 28-03-2018 IPR025659 Tubby C-terminal-like domain CPF12_RS07970 00738e7a6bb71cd05402755eff18cf7b 332 Gene3D G3DSA:1.20.1250.20 130 330 8.5E-12 T 28-03-2018 CPF12_RS07970 00738e7a6bb71cd05402755eff18cf7b 332 SUPERFAMILY SSF103473 4 323 2.22E-18 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS07970 00738e7a6bb71cd05402755eff18cf7b 332 Pfam PF07690 Major Facilitator Superfamily 6 291 2.4E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS10775 4b27a9df0c8dbec8ab9bb193ea4ca481 113 Pfam PF13564 DoxX-like family 7 106 1.8E-19 T 28-03-2018 IPR032808 DoxX family CPF12_RS02065 7cd31b6dc13e2444a4e1541bcb3010a1 179 Pfam PF02620 Uncharacterized ACR, COG1399 56 173 2.0E-16 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CPF12_RS02335 a5dd966f9976012c1dc004b3435f4ffb 182 Gene3D G3DSA:2.40.50.120 49 174 3.9E-5 T 28-03-2018 CPF12_RS04675 7dac11beacf32b7e97ae015be365cd51 203 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CPF12_RS04675 7dac11beacf32b7e97ae015be365cd51 203 Gene3D G3DSA:2.160.10.10 1 199 1.3E-50 T 28-03-2018 CPF12_RS04675 7dac11beacf32b7e97ae015be365cd51 203 Pfam PF12464 Maltose acetyltransferase 6 58 5.5E-11 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CPF12_RS04675 7dac11beacf32b7e97ae015be365cd51 203 SUPERFAMILY SSF51161 30 195 8.32E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like CPF12_RS04675 7dac11beacf32b7e97ae015be365cd51 203 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 1.1E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CPF12_RS04675 7dac11beacf32b7e97ae015be365cd51 203 SMART SM01266 4 59 7.2E-12 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CPF12_RS08890 e64e79c06fbb0bc74205584026d6db2c 237 Gene3D G3DSA:3.30.1890.10 36 158 1.9E-6 T 28-03-2018 CPF12_RS08890 e64e79c06fbb0bc74205584026d6db2c 237 Pfam PF02706 Chain length determinant protein 2 91 1.1E-16 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CPF12_RS08385 947475f9202178dfec4328289e60aa88 285 PIRSF PIRSF035875 1 284 3.1E-71 T 28-03-2018 IPR017039 Virulence factor BrkB CPF12_RS08385 947475f9202178dfec4328289e60aa88 285 Pfam PF03631 Virulence factor BrkB 18 267 1.3E-62 T 28-03-2018 IPR017039 Virulence factor BrkB CPF12_RS08385 947475f9202178dfec4328289e60aa88 285 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 7 265 2.5E-44 T 28-03-2018 IPR017039 Virulence factor BrkB CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 Gene3D G3DSA:3.90.1180.10 1 145 2.4E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 142 1.3E-60 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 140 27.275 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 Pfam PF00572 Ribosomal protein L13 16 138 1.5E-54 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 PIRSF PIRSF002181 1 144 3.4E-49 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CPF12_RS06220 043a8e24bdf128bd3216c623d027df76 145 SUPERFAMILY SSF52161 3 139 4.19E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CPF12_RS02570 b5a9769b9ea9176b2f0bc4a51bbd917d 150 Pfam PF13673 Acetyltransferase (GNAT) domain 41 145 2.7E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS02570 b5a9769b9ea9176b2f0bc4a51bbd917d 150 SUPERFAMILY SSF55729 7 147 1.67E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS02570 b5a9769b9ea9176b2f0bc4a51bbd917d 150 Gene3D G3DSA:3.40.630.30 1 148 2.2E-31 T 28-03-2018 CPF12_RS00830 f4950673ea3636e22451f4db4045f177 274 SUPERFAMILY SSF52402 3 272 2.88E-81 T 28-03-2018 CPF12_RS00830 f4950673ea3636e22451f4db4045f177 274 Gene3D G3DSA:3.40.50.620 2 273 2.9E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS00830 f4950673ea3636e22451f4db4045f177 274 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 267 30.277 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CPF12_RS00830 f4950673ea3636e22451f4db4045f177 274 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 274 4.5E-73 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CPF12_RS00830 f4950673ea3636e22451f4db4045f177 274 Pfam PF02540 NAD synthase 23 264 3.5E-65 T 28-03-2018 IPR022310 NAD/GMP synthase CPF12_RS00945 800f947996783455b1624ffdaf0cf6af 315 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 294 1.2E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CPF12_RS00945 800f947996783455b1624ffdaf0cf6af 315 Gene3D G3DSA:1.10.3470.10 3 298 2.5E-45 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS10425 29ed73b1bbfac5a7f785b723abddb1b7 104 Pfam PF05103 DivIVA protein 8 64 1.3E-16 T 28-03-2018 IPR007793 DivIVA family CPF12_RS10425 29ed73b1bbfac5a7f785b723abddb1b7 104 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 3.7E-16 T 28-03-2018 IPR019933 DivIVA domain CPF12_RS10425 29ed73b1bbfac5a7f785b723abddb1b7 104 PIRSF PIRSF029938 1 104 4.6E-37 T 28-03-2018 IPR011229 Cell cycle protein GpsB CPF12_RS03885 9e1894a934a0c1894dcccb043cd52306 123 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 116 1.1E-36 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain CPF12_RS03885 9e1894a934a0c1894dcccb043cd52306 123 Gene3D G3DSA:3.40.50.510 1 119 1.6E-24 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CPF12_RS03885 9e1894a934a0c1894dcccb043cd52306 123 Pfam PF03610 PTS system fructose IIA component 5 112 3.3E-23 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CPF12_RS03885 9e1894a934a0c1894dcccb043cd52306 123 SUPERFAMILY SSF53062 4 121 5.89E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CPF12_RS04365 ebe293872fd1f6c5f16755f65d74c4c9 431 Pfam PF00860 Permease family 6 384 1.7E-110 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CPF12_RS04365 ebe293872fd1f6c5f16755f65d74c4c9 431 TIGRFAM TIGR03173 pbuX: xanthine permease 10 416 2.1E-160 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CPF12_RS04365 ebe293872fd1f6c5f16755f65d74c4c9 431 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 414 6.4E-131 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CPF12_RS04365 ebe293872fd1f6c5f16755f65d74c4c9 431 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 331 351 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CPF12_RS06610 7bfda3ef6d132bee0e93d8f991228b2f 180 Pfam PF13302 Acetyltransferase (GNAT) domain 16 150 8.9E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS06610 7bfda3ef6d132bee0e93d8f991228b2f 180 Gene3D G3DSA:3.40.630.30 1 175 2.6E-17 T 28-03-2018 CPF12_RS06610 7bfda3ef6d132bee0e93d8f991228b2f 180 SUPERFAMILY SSF55729 12 151 6.38E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS09930 1548e76882fe7f515a3d2fcdc610893d 129 SUPERFAMILY SSF159888 10 125 4.45E-26 T 28-03-2018 CPF12_RS09930 1548e76882fe7f515a3d2fcdc610893d 129 Pfam PF08818 Domain of unknown function (DU1801) 24 115 2.3E-12 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CPF12_RS01275 6ed304936f5286d4998ee9e5fbcba716 101 Pfam PF11192 Protein of unknown function (DUF2977) 1 61 6.9E-17 T 28-03-2018 IPR021358 Protein of unknown function DUF2977 CPF12_RS03855 e777efd2896247a0174ce85406dfe0d5 280 Gene3D G3DSA:1.10.3720.10 43 280 3.3E-35 T 28-03-2018 CPF12_RS03855 e777efd2896247a0174ce85406dfe0d5 280 SUPERFAMILY SSF161098 88 272 1.44E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS03855 e777efd2896247a0174ce85406dfe0d5 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 275 3.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS10460 47318068dd806fa51dc160d23bf6a935 347 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 35 346 6.6E-147 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CPF12_RS10460 47318068dd806fa51dc160d23bf6a935 347 SUPERFAMILY SSF47240 32 345 1.48E-98 T 28-03-2018 IPR009078 Ferritin-like superfamily CPF12_RS10460 47318068dd806fa51dc160d23bf6a935 347 PIRSF PIRSF000355 10 344 9.8E-77 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10460 47318068dd806fa51dc160d23bf6a935 347 Pfam PF00268 Ribonucleotide reductase, small chain 38 303 4.3E-86 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CPF12_RS10460 47318068dd806fa51dc160d23bf6a935 347 Gene3D G3DSA:1.10.620.20 8 321 1.6E-76 T 28-03-2018 CPF12_RS07320 85fccdc9e748b63f3f78c32e33f1fdc1 196 SUPERFAMILY SSF56796 7 162 5.36E-26 T 28-03-2018 CPF12_RS07320 85fccdc9e748b63f3f78c32e33f1fdc1 196 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 163 2.3E-23 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CPF12_RS07320 85fccdc9e748b63f3f78c32e33f1fdc1 196 Gene3D G3DSA:3.40.50.1970 1 164 1.2E-23 T 28-03-2018 CPF12_RS08775 5ce18632f6731c516d490a59432c4cb8 116 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 108 1.2E-12 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS08775 5ce18632f6731c516d490a59432c4cb8 116 SUPERFAMILY SSF159121 32 108 3.66E-10 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 Gene3D G3DSA:2.10.109.10 24 163 1.1E-40 T 28-03-2018 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 SUPERFAMILY SSF51306 26 161 5.91E-49 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 ProSitePatterns PS00760 Signal peptidases I lysine active site. 78 90 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 Pfam PF00717 Peptidase S24-like 34 100 3.8E-22 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 8.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 76 88 8.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 127 146 8.3E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS11785 b5ec73e6f83ed3ee1c7bd5d6b6d5ae40 168 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 161 1.1E-51 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CPF12_RS07840 e484906533798f5e3fd4c55b048bed6e 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 9.2E-71 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CPF12_RS07840 e484906533798f5e3fd4c55b048bed6e 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.8E-221 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CPF12_RS07840 e484906533798f5e3fd4c55b048bed6e 465 SUPERFAMILY SSF101960 32 462 1.44E-135 T 28-03-2018 CPF12_RS00535 23504d0ad4b4af830593bebee60a2927 233 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 38 231 1.8E-51 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CPF12_RS00535 23504d0ad4b4af830593bebee60a2927 233 Pfam PF04973 Nicotinamide mononucleotide transporter 39 227 2.1E-49 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CPF12_RS11365 144439efb775e7d5fe9fc0dfe13002ca 108 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 104 3.9E-12 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS11365 144439efb775e7d5fe9fc0dfe13002ca 108 SUPERFAMILY SSF159121 31 106 1.96E-7 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CPF12_RS05555 d318ac8e587b21b573905367b6052d6f 106 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 18 90 5.6E-14 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CPF12_RS05555 d318ac8e587b21b573905367b6052d6f 106 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 10 100 2.6E-33 T 28-03-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 CPF12_RS00145 4bb6d94df178dbf5e97a918a865ddf92 166 Pfam PF00583 Acetyltransferase (GNAT) family 33 140 2.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS00145 4bb6d94df178dbf5e97a918a865ddf92 166 Gene3D G3DSA:3.40.630.30 1 165 3.9E-25 T 28-03-2018 CPF12_RS00145 4bb6d94df178dbf5e97a918a865ddf92 166 SUPERFAMILY SSF55729 1 164 7.27E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS09210 e1bf98e3ed08ae6f00add0a67d8a5b06 233 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 229 6.5E-71 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CPF12_RS09210 e1bf98e3ed08ae6f00add0a67d8a5b06 233 Gene3D G3DSA:3.40.50.150 1 167 5.9E-12 T 28-03-2018 CPF12_RS09210 e1bf98e3ed08ae6f00add0a67d8a5b06 233 PIRSF PIRSF018637 4 233 5.3E-77 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CPF12_RS06270 542534c0068c0285a07f293edd92f348 248 Pfam PF02361 Cobalt transport protein 7 218 9.6E-21 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CPF12_RS02950 1689d94cb0a1efeabfcdcbd23590347c 131 Gene3D G3DSA:1.10.260.40 6 131 9.2E-20 T 28-03-2018 CPF12_RS02950 1689d94cb0a1efeabfcdcbd23590347c 131 Pfam PF01381 Helix-turn-helix 18 72 8.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS02950 1689d94cb0a1efeabfcdcbd23590347c 131 SUPERFAMILY SSF47413 12 76 9.65E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CPF12_RS02950 1689d94cb0a1efeabfcdcbd23590347c 131 SMART SM00530 17 72 2.4E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CPF12_RS00525 5229be150c7ee174edb1d16b85a926e1 134 Pfam PF03788 LrgA family 21 112 9.8E-24 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CPF12_RS07955 1163c7850114ceb3fd27bb5236f0f006 409 Pfam PF07690 Major Facilitator Superfamily 15 360 3.1E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CPF12_RS07955 1163c7850114ceb3fd27bb5236f0f006 409 SUPERFAMILY SSF103473 6 395 2.09E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CPF12_RS07955 1163c7850114ceb3fd27bb5236f0f006 409 Gene3D G3DSA:1.20.1250.20 1 204 3.3E-20 T 28-03-2018 CPF12_RS07955 1163c7850114ceb3fd27bb5236f0f006 409 Gene3D G3DSA:1.20.1250.20 205 401 4.3E-21 T 28-03-2018 CPF12_RS03755 5893a8b71224c590b949452db91f2e3f 442 Pfam PF00860 Permease family 26 402 6.1E-51 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CPF12_RS03755 5893a8b71224c590b949452db91f2e3f 442 PIRSF PIRSF005353 2 442 1.3E-173 T 28-03-2018 IPR026033 Purine permease PbuG-like CPF12_RS07960 8a360bc45799359cf3f991264123245e 260 Gene3D G3DSA:3.40.50.1820 1 258 5.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS07960 8a360bc45799359cf3f991264123245e 260 Pfam PF12146 Serine aminopeptidase, S33 24 232 1.1E-14 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CPF12_RS07960 8a360bc45799359cf3f991264123245e 260 SUPERFAMILY SSF53474 1 251 9.26E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS04915 a5acd3785626b3f2eb338ae5e6c1452e 154 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 56 72 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS04915 a5acd3785626b3f2eb338ae5e6c1452e 154 Gene3D G3DSA:3.40.930.10 5 154 7.4E-42 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS04915 a5acd3785626b3f2eb338ae5e6c1452e 154 SUPERFAMILY SSF55804 6 153 8.24E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CPF12_RS04915 a5acd3785626b3f2eb338ae5e6c1452e 154 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 10 151 3.3E-42 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CPF12_RS04915 a5acd3785626b3f2eb338ae5e6c1452e 154 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 11 138 2.1E-36 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CPF12_RS07375 646c14243917222d7a5573f0a9a14416 205 Pfam PF08242 Methyltransferase domain 45 140 2.5E-11 T 28-03-2018 IPR013217 Methyltransferase type 12 CPF12_RS07375 646c14243917222d7a5573f0a9a14416 205 SUPERFAMILY SSF53335 5 182 7.99E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS07375 646c14243917222d7a5573f0a9a14416 205 Gene3D G3DSA:3.40.50.150 3 201 4.3E-21 T 28-03-2018 CPF12_RS09375 a5fa5f46800deaf2351630b2981a9f06 183 Pfam PF00293 NUDIX domain 43 156 2.2E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CPF12_RS09375 a5fa5f46800deaf2351630b2981a9f06 183 SUPERFAMILY SSF55811 8 180 1.25E-47 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CPF12_RS09375 a5fa5f46800deaf2351630b2981a9f06 183 Gene3D G3DSA:3.90.79.10 4 182 6.1E-40 T 28-03-2018 CPF12_RS11030 ef3a15841d965c9e22de4741b76b4e65 188 SMART SM00855 3 146 2.0E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS11030 ef3a15841d965c9e22de4741b76b4e65 188 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 161 3.4E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CPF12_RS11030 ef3a15841d965c9e22de4741b76b4e65 188 PIRSF PIRSF000709 2 163 1.6E-6 T 28-03-2018 CPF12_RS11030 ef3a15841d965c9e22de4741b76b4e65 188 Gene3D G3DSA:3.40.50.1240 1 176 2.2E-29 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS11030 ef3a15841d965c9e22de4741b76b4e65 188 SUPERFAMILY SSF53254 1 152 2.06E-30 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 SUPERFAMILY SSF54523 8 81 4.19E-13 T 28-03-2018 CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 PIRSF PIRSF029928 1 100 2.0E-30 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 1.1E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 27 3.7E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 PRINTS PR00813 Bacterial general secretion pathway protein G signature 7 32 1.6E-9 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 1.6E-9 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CPF12_RS01610 3bd50f2c550162fbf551dd00f4ba7393 100 Gene3D G3DSA:3.30.700.10 8 100 1.4E-11 T 28-03-2018 CPF12_RS00185 5f02b113002583e8735715037b4edc6a 482 TIGRFAM TIGR02518 EutH_ACDH: acetaldehyde dehydrogenase (acetylating) 4 481 2.3E-236 T 28-03-2018 IPR013357 Acetaldehyde dehydrogenase, acetylating CPF12_RS00185 5f02b113002583e8735715037b4edc6a 482 Gene3D G3DSA:3.40.605.10 2 233 3.4E-31 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS00185 5f02b113002583e8735715037b4edc6a 482 SUPERFAMILY SSF53720 9 448 2.09E-81 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CPF12_RS00185 5f02b113002583e8735715037b4edc6a 482 Pfam PF00171 Aldehyde dehydrogenase family 8 328 5.0E-25 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CPF12_RS00185 5f02b113002583e8735715037b4edc6a 482 Gene3D G3DSA:3.40.309.10 234 405 1.4E-26 T 28-03-2018 CPF12_RS04050 1fa3dd7f66b180d3ae0eade91652fb27 110 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 75 108 7.8E-9 T 28-03-2018 CPF12_RS04050 1fa3dd7f66b180d3ae0eade91652fb27 110 Pfam PF00746 LPXTG cell wall anchor motif 74 106 2.5E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS12390 2af12d1b3de3c885e9182d96d2202ff1 281 Pfam PF04536 TPM domain 42 163 4.3E-32 T 28-03-2018 IPR007621 TPM domain CPF12_RS10860 13bfd328eaab45ce5c730e6dda6e7869 433 Pfam PF01610 Transposase 168 422 1.5E-57 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS10860 13bfd328eaab45ce5c730e6dda6e7869 433 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 3.8E-7 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS03070 d071848589a06a8ad1e83b0864071533 188 Pfam PF03358 NADPH-dependent FMN reductase 1 143 6.2E-31 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CPF12_RS03070 d071848589a06a8ad1e83b0864071533 188 Gene3D G3DSA:3.40.50.360 1 178 9.8E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS03070 d071848589a06a8ad1e83b0864071533 188 SUPERFAMILY SSF52218 1 166 6.21E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 8.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 8.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 8.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 SMART SM00347 26 126 4.6E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 Pfam PF12802 MarR family 32 90 1.4E-12 T 28-03-2018 CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 SUPERFAMILY SSF46785 30 140 9.93E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00765 38af4891e6bfaf5616ae5bd70bba2013 150 Gene3D G3DSA:1.10.10.10 6 147 1.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS06590 edaf37251c50531895dbfec9cf5c5534 399 Pfam PF04932 O-Antigen ligase 198 338 8.7E-21 T 28-03-2018 IPR007016 O-antigen ligase-related CPF12_RS07385 3f54053e7663e4e88aa548d963abf927 48 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 8 48 1.3E-13 T 28-03-2018 IPR021008 Protein of unknown function DUF3687 CPF12_RS02205 fbf773aadd57be7e2853ffe00c09fba2 371 Pfam PF00676 Dehydrogenase E1 component 54 343 7.6E-95 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CPF12_RS02205 fbf773aadd57be7e2853ffe00c09fba2 371 Gene3D G3DSA:3.40.50.970 2 364 1.1E-80 T 28-03-2018 CPF12_RS02205 fbf773aadd57be7e2853ffe00c09fba2 371 SUPERFAMILY SSF52518 11 366 4.43E-99 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CPF12_RS02205 fbf773aadd57be7e2853ffe00c09fba2 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 363 5.9E-139 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CPF12_RS09955 de4764753a85566366e70d8fa104e387 215 Pfam PF09335 SNARE associated Golgi protein 49 175 2.7E-24 T 28-03-2018 IPR032816 SNARE associated Golgi protein CPF12_RS04175 301566e3c28f80c820d5c0c79bff63d9 290 Pfam PF00005 ABC transporter 17 153 5.9E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS04175 301566e3c28f80c820d5c0c79bff63d9 290 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CPF12_RS04175 301566e3c28f80c820d5c0c79bff63d9 290 SUPERFAMILY SSF52540 2 217 7.26E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS04175 301566e3c28f80c820d5c0c79bff63d9 290 Gene3D G3DSA:3.40.50.300 1 227 6.8E-38 T 28-03-2018 CPF12_RS04175 301566e3c28f80c820d5c0c79bff63d9 290 SMART SM00382 25 203 4.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS05610 08376bbc2d950f3e646e2ccc9aa9beb8 337 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 222 2.2E-79 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CPF12_RS05610 08376bbc2d950f3e646e2ccc9aa9beb8 337 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 325 7.4E-102 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CPF12_RS05610 08376bbc2d950f3e646e2ccc9aa9beb8 337 PIRSF PIRSF000267 1 337 2.1E-110 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CPF12_RS08495 91f39c395d8b1f399f2f68377d7c8a96 489 Gene3D G3DSA:1.10.10.630 218 277 0.15 T 28-03-2018 IPR034829 DnaD-like domain CPF12_RS08495 91f39c395d8b1f399f2f68377d7c8a96 489 Pfam PF07261 Replication initiation and membrane attachment 329 394 4.2E-8 T 28-03-2018 IPR006343 DnaD domain CPF12_RS08495 91f39c395d8b1f399f2f68377d7c8a96 489 Gene3D G3DSA:1.10.10.630 316 393 8.4E-9 T 28-03-2018 IPR034829 DnaD-like domain CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 Gene3D G3DSA:3.30.1360.60 451 526 3.9E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 Pfam PF00367 phosphotransferase system, EIIB 455 487 4.1E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 SUPERFAMILY SSF55604 453 526 1.44E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 Pfam PF02378 Phosphotransferase system, EIIC 22 360 1.0E-82 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 465 482 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 419 512 7.4E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CPF12_RS00730 c69c746ff7bf98aae4adc206cc08da7e 532 TIGRFAM TIGR02004 PTS-IIBC-malX: PTS system, maltose and glucose-specific IIBC component 13 526 3.9E-258 T 28-03-2018 IPR011301 PTS system, maltose/glucose-specific IIBC component GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.208|MetaCyc: PWY-6619 CPF12_RS01755 3a1dd0a8806c84606becfb026cb6e9d6 138 SUPERFAMILY SSF52788 4 135 2.22E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CPF12_RS01755 3a1dd0a8806c84606becfb026cb6e9d6 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 133 1.2E-20 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CPF12_RS01755 3a1dd0a8806c84606becfb026cb6e9d6 138 SMART SM00226 4 136 4.5E-55 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CPF12_RS01755 3a1dd0a8806c84606becfb026cb6e9d6 138 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 133 4.3E-60 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CPF12_RS01755 3a1dd0a8806c84606becfb026cb6e9d6 138 Gene3D G3DSA:3.40.50.2300 1 136 3.9E-39 T 28-03-2018 CPF12_RS08500 7aead6afe37c19a44b18c87b3a9d3f6f 307 Gene3D G3DSA:3.40.50.300 103 300 7.0E-18 T 28-03-2018 CPF12_RS08500 7aead6afe37c19a44b18c87b3a9d3f6f 307 Pfam PF01695 IstB-like ATP binding protein 159 271 9.6E-9 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CPF12_RS08500 7aead6afe37c19a44b18c87b3a9d3f6f 307 SUPERFAMILY SSF52540 150 271 3.63E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS08500 7aead6afe37c19a44b18c87b3a9d3f6f 307 Pfam PF07319 Primosomal protein DnaI N-terminus 1 93 3.5E-20 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal CPF12_RS10880 a1a7784cb55adbaafd9e4d645bc005f9 721 Pfam PF10101 Predicted membrane protein (DUF2339) 120 705 6.3E-9 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 Pfam PF00464 Serine hydroxymethyltransferase 4 380 7.4E-173 T 28-03-2018 CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 53.457 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 Gene3D G3DSA:3.40.640.10 33 269 7.5E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 SUPERFAMILY SSF53383 2 410 1.77E-177 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 Gene3D G3DSA:3.90.1150.10 270 410 3.4E-55 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CPF12_RS06450 4fd6b7a80929a36ee552827534f3efc6 411 PIRSF PIRSF000412 1 408 2.4E-169 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CPF12_RS10690 5c43738f62d4f71dd0e507388911435e 207 Pfam PF01184 GPR1/FUN34/yaaH family 8 193 5.2E-20 T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 CPF12_RS00300 8dc5fd4dc6ea5b86855b3e79872426a1 305 Gene3D G3DSA:1.10.3720.10 71 300 2.1E-38 T 28-03-2018 CPF12_RS00300 8dc5fd4dc6ea5b86855b3e79872426a1 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 298 3.2E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS00300 8dc5fd4dc6ea5b86855b3e79872426a1 305 SUPERFAMILY SSF161098 17 304 1.31E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04835 b58569a06fe44c5df32bb45352f33cbf 253 Gene3D G3DSA:3.30.70.330 30 145 7.1E-4 T 28-03-2018 CPF12_RS00365 91bc4afc71534bf74d2aa42f00032f74 366 Pfam PF02378 Phosphotransferase system, EIIC 16 289 1.8E-10 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS00365 91bc4afc71534bf74d2aa42f00032f74 366 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 8 337 3.3E-77 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CPF12_RS04125 41364c83d8ca08a48dc568da83a19ef3 351 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 2 346 2.7E-93 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CPF12_RS04125 41364c83d8ca08a48dc568da83a19ef3 351 Pfam PF02378 Phosphotransferase system, EIIC 3 274 5.2E-48 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CPF12_RS00450 d5944f75923885b06e532914304eba29 126 Pfam PF01610 Transposase 2 93 1.4E-18 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS01115 a7359c1074101e99be184ee315c928a9 226 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 3 81 4.1E-17 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal CPF12_RS02885 65d425a29a5b9635b308b52ad049d259 413 Pfam PF00149 Calcineurin-like phosphoesterase 4 199 9.6E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CPF12_RS02885 65d425a29a5b9635b308b52ad049d259 413 SUPERFAMILY SSF56300 4 279 4.72E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS02885 65d425a29a5b9635b308b52ad049d259 413 Gene3D G3DSA:3.60.21.10 80 248 1.3E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS02885 65d425a29a5b9635b308b52ad049d259 413 Gene3D G3DSA:3.60.21.10 1 79 7.5E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CPF12_RS02885 65d425a29a5b9635b308b52ad049d259 413 PIRSF PIRSF033091 1 413 3.6E-115 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CPF12_RS07945 29dd49cd2d287899d5ded7ad9e011fbf 135 PIRSF PIRSF012565 1 134 2.9E-49 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CPF12_RS07945 29dd49cd2d287899d5ded7ad9e011fbf 135 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 3.6E-37 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CPF12_RS11995 023baa237543c14ff9321b8bf71dfc93 189 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS11995 023baa237543c14ff9321b8bf71dfc93 189 SUPERFAMILY SSF52317 3 182 2.22E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11995 023baa237543c14ff9321b8bf71dfc93 189 PIRSF PIRSF005639 1 187 1.5E-57 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS11995 023baa237543c14ff9321b8bf71dfc93 189 Gene3D G3DSA:3.40.50.880 1 189 5.4E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CPF12_RS11995 023baa237543c14ff9321b8bf71dfc93 189 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 181 2.7E-53 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS11995 023baa237543c14ff9321b8bf71dfc93 189 Pfam PF01174 SNO glutamine amidotransferase family 6 183 2.1E-46 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CPF12_RS02780 7b6bb006a57878f95b29f5349ee9b711 183 SUPERFAMILY SSF102114 40 113 3.34E-9 T 28-03-2018 CPF12_RS02780 7b6bb006a57878f95b29f5349ee9b711 183 PIRSF PIRSF000368 10 182 8.7E-62 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CPF12_RS02780 7b6bb006a57878f95b29f5349ee9b711 183 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 19 169 1.5E-48 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CPF12_RS02780 7b6bb006a57878f95b29f5349ee9b711 183 Pfam PF13353 4Fe-4S single cluster domain 28 167 1.5E-47 T 28-03-2018 CPF12_RS02780 7b6bb006a57878f95b29f5349ee9b711 183 Gene3D G3DSA:3.80.30.10 77 177 1.4E-11 T 28-03-2018 CPF12_RS04325 755032c5ae51d940449fe72544ca78b6 269 SUPERFAMILY SSF53649 3 256 2.62E-37 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CPF12_RS04325 755032c5ae51d940449fe72544ca78b6 269 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 216 1.2E-16 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CPF12_RS04325 755032c5ae51d940449fe72544ca78b6 269 Gene3D G3DSA:3.40.720.10 2 262 7.7E-35 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CPF12_RS08810 43bfda3704c55c9f95e33ad1e0bf496b 171 SUPERFAMILY SSF53613 1 120 1.18E-5 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS08810 43bfda3704c55c9f95e33ad1e0bf496b 171 Gene3D G3DSA:3.40.1190.20 1 161 1.8E-4 T 28-03-2018 IPR029056 Ribokinase-like CPF12_RS08810 43bfda3704c55c9f95e33ad1e0bf496b 171 Pfam PF02110 Hydroxyethylthiazole kinase family 15 133 5.2E-10 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CPF12_RS07655 9bbc13dc80f7efadff119782ea0c67e9 163 Gene3D G3DSA:3.10.450.50 33 161 1.2E-4 T 28-03-2018 CPF12_RS00880 fc3814b81167629bc17ab449ccb6f6dd 268 Pfam PF01061 ABC-2 type transporter 27 226 2.4E-24 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CPF12_RS09035 9f93c5fc19012cc8b1b21947337eb490 115 SUPERFAMILY SSF50118 1 112 5.23E-39 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CPF12_RS09035 9f93c5fc19012cc8b1b21947337eb490 115 Gene3D G3DSA:2.30.30.110 1 115 1.1E-35 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CPF12_RS09035 9f93c5fc19012cc8b1b21947337eb490 115 PIRSF PIRSF033490 1 112 1.1E-36 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CPF12_RS09035 9f93c5fc19012cc8b1b21947337eb490 115 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 110 2.4E-31 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CPF12_RS10615 9bf1ad1fbbc7931388a7df0d9dbf06b8 145 SUPERFAMILY SSF51316 6 144 4.97E-56 T 28-03-2018 IPR011057 Mss4-like CPF12_RS10615 9bf1ad1fbbc7931388a7df0d9dbf06b8 145 Gene3D G3DSA:2.170.150.20 2 145 1.4E-52 T 28-03-2018 CPF12_RS10615 9bf1ad1fbbc7931388a7df0d9dbf06b8 145 Pfam PF01641 SelR domain 11 128 3.7E-48 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10615 9bf1ad1fbbc7931388a7df0d9dbf06b8 145 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 8 137 2.3E-58 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10615 9bf1ad1fbbc7931388a7df0d9dbf06b8 145 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 1 129 35.801 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CPF12_RS10950 7c9aaae6d40fe718880b93457d66e3cc 160 Pfam PF13673 Acetyltransferase (GNAT) domain 42 124 2.3E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS10950 7c9aaae6d40fe718880b93457d66e3cc 160 SUPERFAMILY SSF55729 11 125 2.79E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS10950 7c9aaae6d40fe718880b93457d66e3cc 160 Gene3D G3DSA:3.40.630.30 7 139 2.0E-13 T 28-03-2018 CPF12_RS00610 0db2605dbbf94623ba5b5ca332bc8c5a 193 Pfam PF04892 VanZ like family 84 189 4.9E-12 T 28-03-2018 IPR006976 VanZ-like CPF12_RS00625 ce8e662538b943956ba0036a20c53b7e 334 Pfam PF05043 Mga helix-turn-helix domain 73 156 1.2E-11 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS00625 ce8e662538b943956ba0036a20c53b7e 334 Gene3D G3DSA:1.10.10.10 84 142 0.012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00625 ce8e662538b943956ba0036a20c53b7e 334 Gene3D G3DSA:1.10.10.10 2 69 1.7E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS00625 ce8e662538b943956ba0036a20c53b7e 334 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 10 53 2.4E-5 T 28-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain CPF12_RS00715 6bc57008a223eb12a802793bdc38678c 133 Pfam PF09945 Predicted membrane protein (DUF2177) 5 125 2.3E-40 T 28-03-2018 IPR018687 Protein of unknown function DUF2177, membrane CPF12_RS04570 f2987d38bad27ee313b6cafeb28f5e38 122 Pfam PF04237 YjbR 15 106 9.1E-15 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CPF12_RS04570 f2987d38bad27ee313b6cafeb28f5e38 122 SUPERFAMILY SSF142906 6 119 1.44E-26 T 28-03-2018 CPF12_RS04985 0132281f2bdbf06dfdb06b84dfdf2e7b 63 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 9 56 1.7E-13 T 28-03-2018 IPR025626 YyzF-like protein CPF12_RS04985 0132281f2bdbf06dfdb06b84dfdf2e7b 63 Pfam PF14116 YyzF-like protein 11 57 6.4E-11 T 28-03-2018 IPR025626 YyzF-like protein CPF12_RS06670 e2651fd157115cee7bf2e08d3e2c022d 409 SUPERFAMILY SSF54001 296 408 2.55E-32 T 28-03-2018 CPF12_RS06670 e2651fd157115cee7bf2e08d3e2c022d 409 Gene3D G3DSA:3.90.20.10 9 139 3.2E-4 T 28-03-2018 CPF12_RS06670 e2651fd157115cee7bf2e08d3e2c022d 409 Pfam PF00877 NlpC/P60 family 312 405 1.6E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CPF12_RS06670 e2651fd157115cee7bf2e08d3e2c022d 409 Gene3D G3DSA:3.90.1720.10 294 409 1.7E-31 T 28-03-2018 CPF12_RS04305 1066cc02c0315f81caea07ca321a3843 258 SUPERFAMILY SSF89550 2 250 6.8E-26 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CPF12_RS04305 1066cc02c0315f81caea07ca321a3843 258 Gene3D G3DSA:3.20.20.140 1 255 1.7E-20 T 28-03-2018 CPF12_RS00650 57ff591645b07119b580f261cd090c98 277 SMART SM00382 30 208 2.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CPF12_RS00650 57ff591645b07119b580f261cd090c98 277 SUPERFAMILY SSF52540 5 225 8.88E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00650 57ff591645b07119b580f261cd090c98 277 Gene3D G3DSA:3.40.50.300 2 249 3.3E-63 T 28-03-2018 CPF12_RS00650 57ff591645b07119b580f261cd090c98 277 Pfam PF00005 ABC transporter 21 161 6.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CPF12_RS09890 879c767a31f34c8ddc853829008dc0bf 326 Gene3D G3DSA:1.10.3470.10 1 325 1.8E-56 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS09890 879c767a31f34c8ddc853829008dc0bf 326 Pfam PF01032 FecCD transport family 16 321 3.8E-78 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS09890 879c767a31f34c8ddc853829008dc0bf 326 SUPERFAMILY SSF81345 3 322 8.63E-64 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS00305 78aea8ef42962b2d9a9e8efdcd3a8b27 293 Gene3D G3DSA:1.10.3720.10 1 292 5.7E-43 T 28-03-2018 CPF12_RS00305 78aea8ef42962b2d9a9e8efdcd3a8b27 293 SUPERFAMILY SSF161098 46 276 1.83E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS00305 78aea8ef42962b2d9a9e8efdcd3a8b27 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 286 7.5E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS06445 35be11914dad0cd1553c1aa40c1393f0 349 SUPERFAMILY SSF55821 15 214 9.77E-65 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CPF12_RS06445 35be11914dad0cd1553c1aa40c1393f0 349 Pfam PF03481 Putative GTP-binding controlling metal-binding 203 340 2.2E-25 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CPF12_RS06445 35be11914dad0cd1553c1aa40c1393f0 349 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 211 9.9E-62 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CPF12_RS06445 35be11914dad0cd1553c1aa40c1393f0 349 Pfam PF01300 Telomere recombination 25 201 2.5E-59 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CPF12_RS06445 35be11914dad0cd1553c1aa40c1393f0 349 PIRSF PIRSF004930 3 346 1.3E-126 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CPF12_RS06445 35be11914dad0cd1553c1aa40c1393f0 349 Gene3D G3DSA:3.90.870.10 4 217 1.6E-82 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CPF12_RS10885 8acf557fb4d3fd870cef477d920c795c 167 Pfam PF07853 Protein of unknown function (DUF1648) 24 69 1.3E-17 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 CPF12_RS04850 054381bf73c02c91a2cebaa3ab1e0d0f 89 Pfam PF12674 Putative zinc ribbon domain 7 89 6.7E-24 T 28-03-2018 IPR025868 Putative zinc ribbon domain CPF12_RS07275 85305dd45df67cbd28f8a568b94324c0 189 Gene3D G3DSA:3.40.50.1820 1 188 4.4E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS07275 85305dd45df67cbd28f8a568b94324c0 189 SUPERFAMILY SSF53474 8 188 7.58E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS05185 1dcab0ed9905b90069f36e118b2b3d56 201 Pfam PF02230 Phospholipase/Carboxylesterase 4 194 3.7E-10 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CPF12_RS05185 1dcab0ed9905b90069f36e118b2b3d56 201 Gene3D G3DSA:3.40.50.1820 4 200 1.1E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS05185 1dcab0ed9905b90069f36e118b2b3d56 201 SUPERFAMILY SSF53474 8 198 2.32E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 SMART SM00421 120 177 2.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 123 137 4.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 165 4.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 153 4.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 Pfam PF00196 Bacterial regulatory proteins, luxR family 123 175 1.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 Gene3D G3DSA:1.10.10.10 9 186 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS03275 d39777a5abf435b55dd538cf9c6b8bdb 193 SUPERFAMILY SSF46894 117 183 3.2E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CPF12_RS08080 6effbad3a41e6f577c063ab931408435 689 Pfam PF00999 Sodium/hydrogen exchanger family 7 419 3.6E-58 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CPF12_RS08080 6effbad3a41e6f577c063ab931408435 689 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 528 3.1E-103 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CPF12_RS01375 b1ea8505e09bebe2e314bff963f412aa 311 Pfam PF13536 Putative multidrug resistance efflux transporter 38 305 3.2E-101 T 28-03-2018 IPR032713 Putative multidrug resistance efflux transporter CPF12_RS03270 0333482a6a3b09ed3b10a43d07664c22 171 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 10 158 2.5E-39 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CPF12_RS03270 0333482a6a3b09ed3b10a43d07664c22 171 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 46 68 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CPF12_RS03270 0333482a6a3b09ed3b10a43d07664c22 171 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 68 4.5E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CPF12_RS00580 c07789e05bc81bce91002bf2ba20626b 1723 Gene3D G3DSA:3.40.50.300 1253 1720 6.3E-19 T 28-03-2018 CPF12_RS00580 c07789e05bc81bce91002bf2ba20626b 1723 SUPERFAMILY SSF52540 1366 1699 8.43E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS00580 c07789e05bc81bce91002bf2ba20626b 1723 Pfam PF12846 AAA-like domain 1390 1696 4.8E-11 T 28-03-2018 CPF12_RS01240 bc6aeba41bd57fe72d6adf03d756ca59 104 Gene3D G3DSA:1.20.1440.50 23 95 2.6E-4 T 28-03-2018 IPR023130 Ta0600-like domain CPF12_RS01240 bc6aeba41bd57fe72d6adf03d756ca59 104 Pfam PF08951 Enterocin A Immunity 23 94 2.2E-6 T 28-03-2018 IPR015046 Enterocin A Immunity CPF12_RS07520 3422f4adbcd6b1c5caf6acec2fcba01a 68 Pfam PF05154 TM2 domain 4 53 1.0E-15 T 28-03-2018 IPR007829 TM2 domain CPF12_RS02715 4729e05191d6d35bca7341693653222d 197 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 9 192 1.3E-35 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane CPF12_RS02715 4729e05191d6d35bca7341693653222d 197 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 7 192 1.2E-24 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane CPF12_RS10275 cc14a6aba68a7e7ccc36ad7b40116669 119 Gene3D G3DSA:3.30.1330.20 2 118 4.8E-42 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CPF12_RS10275 cc14a6aba68a7e7ccc36ad7b40116669 119 Pfam PF09585 Conserved hypothetical protein (Lin0512_fam) 5 116 1.4E-39 T 28-03-2018 IPR011719 Conserved hypothetical protein CHP02058 CPF12_RS10275 cc14a6aba68a7e7ccc36ad7b40116669 119 TIGRFAM TIGR02058 lin0512_fam: conserved hypothetical protein 3 119 3.3E-51 T 28-03-2018 IPR011719 Conserved hypothetical protein CHP02058 CPF12_RS11560 cbcf4e301117ca1b537ef76f28d82165 262 Pfam PF06182 ABC-2 family transporter protein 35 254 2.2E-16 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CPF12_RS08755 2ffe1d6976d7182b0d2873abc0c5e81b 483 Pfam PF01425 Amidase 24 463 7.4E-157 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CPF12_RS08755 2ffe1d6976d7182b0d2873abc0c5e81b 483 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CPF12_RS08755 2ffe1d6976d7182b0d2873abc0c5e81b 483 Gene3D G3DSA:3.90.1300.10 1 482 3.4E-171 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CPF12_RS08755 2ffe1d6976d7182b0d2873abc0c5e81b 483 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 93.911 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CPF12_RS08755 2ffe1d6976d7182b0d2873abc0c5e81b 483 SUPERFAMILY SSF75304 1 476 2.88E-163 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CPF12_RS08755 2ffe1d6976d7182b0d2873abc0c5e81b 483 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 474 4.0E-199 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CPF12_RS06800 91e467da8c9b9a97360600aad67f74b0 68 Pfam PF10783 Protein of unknown function (DUF2599) 4 67 2.0E-14 T 28-03-2018 IPR019719 Protein of unknown function DUF2599 CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 159 6.4E-12 T 28-03-2018 CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 SUPERFAMILY SSF51735 1 197 2.22E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 Gene3D G3DSA:3.40.50.720 1 199 7.6E-31 T 28-03-2018 CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 144 3.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 3.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS01350 38cd44ef0dbee4f88008a2c4b31f1d0f 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 3.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CPF12_RS08025 535ef845c743ce2fda45f5024b3755a1 88 Gene3D G3DSA:1.10.10.10 38 88 4.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS08025 535ef845c743ce2fda45f5024b3755a1 88 SUPERFAMILY SSF46955 38 86 7.87E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain CPF12_RS00140 b48abaf35f9b49123872ab2bbda07340 545 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 539 1.8E-171 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CPF12_RS00140 b48abaf35f9b49123872ab2bbda07340 545 Pfam PF02652 L-lactate permease 16 537 3.0E-169 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CPF12_RS07920 cb7a784c61d0e86787042f7908a52f43 449 PIRSF PIRSF002746 1 449 6.9E-166 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CPF12_RS07920 cb7a784c61d0e86787042f7908a52f43 449 Pfam PF02447 GntP family permease 1 448 7.4E-167 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CPF12_RS07920 cb7a784c61d0e86787042f7908a52f43 449 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 449 8.5E-181 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CPF12_RS03880 0e441d26b187d3d5011ef2bf5ff47b3f 198 Pfam PF02734 DAK2 domain 31 191 3.3E-45 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS03880 0e441d26b187d3d5011ef2bf5ff47b3f 198 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 9 191 6.9E-69 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CPF12_RS03880 0e441d26b187d3d5011ef2bf5ff47b3f 198 SUPERFAMILY SSF101473 2 192 1.29E-53 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS03880 0e441d26b187d3d5011ef2bf5ff47b3f 198 SMART SM01120 31 192 6.9E-62 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CPF12_RS01180 6fd5bba4b657db77b297a95fd51c3d8b 490 SUPERFAMILY SSF52540 168 415 5.78E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CPF12_RS01180 6fd5bba4b657db77b297a95fd51c3d8b 490 Gene3D G3DSA:3.40.50.300 150 424 2.2E-15 T 28-03-2018 CPF12_RS01180 6fd5bba4b657db77b297a95fd51c3d8b 490 Pfam PF13175 AAA ATPase domain 197 403 5.5E-12 T 28-03-2018 CPF12_RS01050 f712cb82e79a4164803d4a8c38ddf8e7 216 Pfam PF01596 O-methyltransferase 16 214 2.3E-52 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CPF12_RS01050 f712cb82e79a4164803d4a8c38ddf8e7 216 SUPERFAMILY SSF53335 20 216 8.82E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CPF12_RS01050 f712cb82e79a4164803d4a8c38ddf8e7 216 Gene3D G3DSA:3.40.50.150 30 207 3.6E-29 T 28-03-2018 CPF12_RS00870 887268c08fdf84e91f346b91b199613d 377 SUPERFAMILY SSF53756 95 376 6.12E-10 T 28-03-2018 CPF12_RS00870 887268c08fdf84e91f346b91b199613d 377 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 16 375 7.1E-55 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CPF12_RS00680 27db111545ee4c157a61d9bc5a8c6f5f 78 Gene3D G3DSA:1.10.1200.10 1 76 1.5E-17 T 28-03-2018 CPF12_RS00680 27db111545ee4c157a61d9bc5a8c6f5f 78 SUPERFAMILY SSF47336 2 74 1.44E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS00680 27db111545ee4c157a61d9bc5a8c6f5f 78 Pfam PF00550 Phosphopantetheine attachment site 4 69 8.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CPF12_RS00680 27db111545ee4c157a61d9bc5a8c6f5f 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 72 0.009 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CPF12_RS11285 1f2262429eae38cefba3dd0941cc2c53 113 SUPERFAMILY SSF46785 6 105 2.67E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11285 1f2262429eae38cefba3dd0941cc2c53 113 Pfam PF01638 HxlR-like helix-turn-helix 17 106 1.9E-32 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CPF12_RS11285 1f2262429eae38cefba3dd0941cc2c53 113 Gene3D G3DSA:1.10.10.10 4 112 6.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS11375 7def11e2a0da6b13c9a23b567fc14454 697 Pfam PF07242 Protein of unknown function (DUF1430) 596 696 1.2E-6 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CPF12_RS09140 8c648bd548f9df14cf0e4b436cf81af5 224 Pfam PF02517 CAAX protease self-immunity 129 215 2.9E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CPF12_RS02430 51e25e57067e1dbf0fb5921dc0f7ed50 264 Pfam PF01610 Transposase 1 253 1.3E-55 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS11730 27cb72b6bf6728d5209e567522d16357 247 Pfam PF10517 Electron transfer DM13 59 145 2.8E-13 T 28-03-2018 IPR019545 DM13 domain CPF12_RS11730 27cb72b6bf6728d5209e567522d16357 247 Pfam PF10517 Electron transfer DM13 163 246 1.5E-15 T 28-03-2018 IPR019545 DM13 domain CPF12_RS00705 6512668ed8295a99d2f6d2f634bb76ca 258 Pfam PF06966 Protein of unknown function (DUF1295) 19 246 5.6E-78 T 28-03-2018 IPR010721 Protein of unknown function DUF1295 CPF12_RS08210 36502b038db83730c1141c78cf65c07e 322 Pfam PF00561 alpha/beta hydrolase fold 72 183 4.1E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CPF12_RS08210 36502b038db83730c1141c78cf65c07e 322 SUPERFAMILY SSF53474 55 317 1.33E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS08210 36502b038db83730c1141c78cf65c07e 322 Gene3D G3DSA:3.40.50.1820 31 319 2.9E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS00750 1d02d282fa5894416f67107bbac397c6 165 Gene3D G3DSA:3.40.630.30 1 160 1.6E-28 T 28-03-2018 CPF12_RS00750 1d02d282fa5894416f67107bbac397c6 165 SUPERFAMILY SSF55729 6 153 1.86E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CPF12_RS00750 1d02d282fa5894416f67107bbac397c6 165 Pfam PF00583 Acetyltransferase (GNAT) family 40 138 8.5E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 SUPERFAMILY SSF116734 2 200 4.91E-42 T 28-03-2018 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 Gene3D G3DSA:3.90.220.20 182 363 9.2E-31 T 28-03-2018 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 Gene3D G3DSA:3.90.220.20 2 181 9.2E-32 T 28-03-2018 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 Gene3D G3DSA:3.90.220.20 364 386 0.34 T 28-03-2018 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 SUPERFAMILY SSF116734 211 384 1.57E-43 T 28-03-2018 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 Pfam PF01420 Type I restriction modification DNA specificity domain 17 188 8.6E-15 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CPF12_RS08285 bf7cd353f2bfc47ec89db6a356d9399a 386 Pfam PF01420 Type I restriction modification DNA specificity domain 217 371 1.1E-20 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CPF12_RS05285 dd4a229afd76f32b1528d74a87717461 182 Pfam PF11188 Protein of unknown function (DUF2975) 72 181 1.1E-7 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CPF12_RS09575 9e8e9a5b9d773dc0431c1f7901eab6fd 225 Pfam PF04298 Putative neutral zinc metallopeptidase 4 220 4.1E-92 T 28-03-2018 IPR007395 Putative neutral zinc metallopeptidase CPF12_RS06230 627c382a7cc94dc0aac9449578a932a0 107 SUPERFAMILY SSF101386 1 104 3.36E-24 T 28-03-2018 CPF12_RS06230 627c382a7cc94dc0aac9449578a932a0 107 PIRSF PIRSF036521 1 107 1.2E-49 T 28-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related CPF12_RS06230 627c382a7cc94dc0aac9449578a932a0 107 Gene3D G3DSA:1.10.287.1080 1 107 4.7E-18 T 28-03-2018 CPF12_RS06230 627c382a7cc94dc0aac9449578a932a0 107 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 4.4E-14 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CPF12_RS10480 08562f4702f34eccda881b526d35c4d8 226 Pfam PF13731 WxL domain surface cell wall-binding 47 225 1.7E-35 T 28-03-2018 IPR027994 WxL domain CPF12_RS03620 14c0fcf471b6e02b0c524ffcfa89c479 101 SUPERFAMILY SSF109797 30 94 5.75E-5 T 28-03-2018 CPF12_RS03870 ce96c7d71137b2fe67e06889409a24f7 249 Pfam PF13350 Tyrosine phosphatase family 4 248 2.6E-48 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CPF12_RS03870 ce96c7d71137b2fe67e06889409a24f7 249 SUPERFAMILY SSF52799 5 248 2.72E-37 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CPF12_RS03870 ce96c7d71137b2fe67e06889409a24f7 249 Gene3D G3DSA:3.90.190.10 14 182 2.5E-18 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CPF12_RS03870 ce96c7d71137b2fe67e06889409a24f7 249 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 138 148 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 CPF12_RS10470 e0a7012443148bb8b8f1f21a5e5f0168 117 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 77 99 0.0019 T 28-03-2018 CPF12_RS00530 19655a35ef73d57924148443705e3528 226 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 226 27.833 T 28-03-2018 IPR024891 Antiholin-like protein LrgB CPF12_RS00530 19655a35ef73d57924148443705e3528 226 Pfam PF04172 LrgB-like family 10 224 9.2E-68 T 28-03-2018 IPR007300 CidB/LrgB family CPF12_RS09825 408c1ba1beded7f65f337828a19e3ec7 307 Pfam PF06161 Protein of unknown function (DUF975) 10 275 1.2E-27 T 28-03-2018 IPR010380 Protein of unknown function DUF975 CPF12_RS11000 9a8bbf8005bc57e684649992c5699fa8 291 SUPERFAMILY SSF51658 6 282 3.67E-45 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS11000 9a8bbf8005bc57e684649992c5699fa8 291 Gene3D G3DSA:3.20.20.150 1 284 4.7E-40 T 28-03-2018 CPF12_RS11000 9a8bbf8005bc57e684649992c5699fa8 291 Pfam PF01261 Xylose isomerase-like TIM barrel 23 241 3.0E-32 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CPF12_RS07805 ba3f684d08f6d32cb8d534a30e697009 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 225 4.6E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07805 ba3f684d08f6d32cb8d534a30e697009 225 SUPERFAMILY SSF161098 14 215 2.09E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS07805 ba3f684d08f6d32cb8d534a30e697009 225 Gene3D G3DSA:1.10.3720.10 10 225 1.2E-39 T 28-03-2018 CPF12_RS03960 36d1494a8d77c5fe301f0b3bd668c991 277 Pfam PF10850 Protein of unknown function (DUF2653) 184 267 9.3E-12 T 28-03-2018 IPR020516 Uncharacterised protein family YxcD CPF12_RS03960 36d1494a8d77c5fe301f0b3bd668c991 277 ProDom PD068665 YXCD 184 274 1.0E-5 T 28-03-2018 IPR020516 Uncharacterised protein family YxcD CPF12_RS01990 1d14f48a166025af740516b35b247d46 165 Pfam PF04472 Cell division protein SepF 81 152 2.6E-25 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CPF12_RS01990 1d14f48a166025af740516b35b247d46 165 Hamap MF_01197 Cell division protein SepF [sepF]. 1 160 18.718 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CPF12_RS04625 3bd6f7511ffb9f3abf15920d7547a1dd 308 Pfam PF03595 Voltage-dependent anion channel 16 294 1.5E-25 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CPF12_RS06595 ccd402b930801c19ba50bbf42f0161da 134 Pfam PF01943 Polysaccharide biosynthesis protein 4 133 4.1E-17 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CPF12_RS08525 6372c76453012c970e40ded6a8983a55 113 Gene3D G3DSA:1.10.10.60 28 81 4.4E-6 T 28-03-2018 CPF12_RS08525 6372c76453012c970e40ded6a8983a55 113 Pfam PF13556 PucR C-terminal helix-turn-helix domain 47 102 3.0E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CPF12_RS03660 af571e3e0bac2036a5b260030d217327 208 Pfam PF07987 Domain of unkown function (DUF1775) 24 149 8.2E-18 T 28-03-2018 IPR012533 YcnI-like CPF12_RS07380 1915e6fae79b86381db5ddba7acb7772 650 Pfam PF00999 Sodium/hydrogen exchanger family 7 408 6.5E-53 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CPF12_RS06505 3e2d12673581b4fc1f7ff557f8a3c0e7 57 Pfam PF06612 Protein of unknown function (DUF1146) 2 45 1.9E-19 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CPF12_RS06505 3e2d12673581b4fc1f7ff557f8a3c0e7 57 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 2 54 3.7E-17 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CPF12_RS03955 d9a115bb6db387ea33a2c4a0d22768bb 186 Pfam PF02417 Chromate transporter 11 174 3.1E-33 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CPF12_RS04650 f02ce9cca9b9292f15699e95369efada 166 Pfam PF07308 Protein of unknown function (DUF1456) 3 79 5.3E-24 T 28-03-2018 IPR009921 Domain of unknown function DUF1456 CPF12_RS04650 f02ce9cca9b9292f15699e95369efada 166 Pfam PF07308 Protein of unknown function (DUF1456) 99 165 6.6E-22 T 28-03-2018 IPR009921 Domain of unknown function DUF1456 CPF12_RS07490 bdf71ddf15d008dfbbc95dd0c23792f0 328 Pfam PF01032 FecCD transport family 18 322 1.0E-82 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS07490 bdf71ddf15d008dfbbc95dd0c23792f0 328 SUPERFAMILY SSF81345 4 322 2.75E-72 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS07490 bdf71ddf15d008dfbbc95dd0c23792f0 328 Gene3D G3DSA:1.10.3470.10 2 325 2.2E-55 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS11425 3516fc24d7159c65a6123c75e7a552fb 292 SUPERFAMILY SSF103481 183 284 1.01E-11 T 28-03-2018 CPF12_RS11425 3516fc24d7159c65a6123c75e7a552fb 292 Pfam PF00892 EamA-like transporter family 7 136 1.2E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CPF12_RS11425 3516fc24d7159c65a6123c75e7a552fb 292 Pfam PF00892 EamA-like transporter family 150 279 1.9E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CPF12_RS11425 3516fc24d7159c65a6123c75e7a552fb 292 SUPERFAMILY SSF103481 37 137 3.01E-12 T 28-03-2018 CPF12_RS01340 b9e963e91a1ed5e8d0c14e9eefc08738 209 Pfam PF01810 LysE type translocator 13 200 6.0E-30 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CPF12_RS01695 f5735cf5688f63d11fe515be4ed845a6 311 Gene3D G3DSA:1.10.3470.10 27 308 6.8E-38 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS01695 f5735cf5688f63d11fe515be4ed845a6 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 302 1.7E-52 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CPF12_RS07485 62724a3f16b0e382c51ce06f2a77c0bf 325 Pfam PF01032 FecCD transport family 20 324 3.5E-77 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CPF12_RS07485 62724a3f16b0e382c51ce06f2a77c0bf 325 Gene3D G3DSA:1.10.3470.10 5 325 2.0E-60 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CPF12_RS07485 62724a3f16b0e382c51ce06f2a77c0bf 325 SUPERFAMILY SSF81345 6 324 1.44E-66 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CPF12_RS09015 64f3f99121d2ab605d1497da78a47967 161 Pfam PF03703 Bacterial PH domain 74 150 2.2E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CPF12_RS00290 d7dcea8398d7a95bcf475bb63b59a086 205 Pfam PF04854 Protein of unknown function, DUF624 16 90 1.2E-13 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CPF12_RS03400 2374a4787d144c47f251dbebf10b7937 127 Pfam PF04241 Protein of unknown function (DUF423) 18 103 1.7E-29 T 28-03-2018 IPR006696 Protein of unknown function DUF423 CPF12_RS06735 0d15617fb6a0a4b4738dabb3ba3d1524 80 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 6 74 4.2E-21 T 28-03-2018 IPR019242 Protein of unknown function DUF2198 CPF12_RS07430 441ca912c858c313c6400e890a3f664e 109 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 75 107 0.0011 T 28-03-2018 CPF12_RS07430 441ca912c858c313c6400e890a3f664e 109 Pfam PF00746 LPXTG cell wall anchor motif 71 109 2.7E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS03300 437df4d12a4e5c567aff36837a0bf81e 274 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 32 274 9.5E-60 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CPF12_RS03300 437df4d12a4e5c567aff36837a0bf81e 274 Gene3D G3DSA:3.40.50.1820 32 274 5.9E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS03300 437df4d12a4e5c567aff36837a0bf81e 274 SUPERFAMILY SSF53474 101 237 1.18E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS03300 437df4d12a4e5c567aff36837a0bf81e 274 SUPERFAMILY SSF53474 33 62 1.18E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CPF12_RS01445 ed7dd45cdf371306f259c2ecd01d08d8 239 PIRSF PIRSF031509 1 239 1.5E-50 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CPF12_RS01445 ed7dd45cdf371306f259c2ecd01d08d8 239 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 122 236 2.6E-31 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CPF12_RS05655 ec274d01a8b7f64462f4f37002645592 80 Pfam PF10704 Protein of unknown function (DUF2508) 2 68 5.0E-11 T 28-03-2018 IPR019644 Protein of unknown function DUF2508 CPF12_RS10915 349505cff2af2a60cb83f5bf5947ffef 316 Gene3D G3DSA:1.10.3720.10 2 302 6.1E-44 T 28-03-2018 CPF12_RS10915 349505cff2af2a60cb83f5bf5947ffef 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 1.7E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS10915 349505cff2af2a60cb83f5bf5947ffef 316 SUPERFAMILY SSF161098 90 296 1.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CPF12_RS04945 705495112ea6af0b5c3b76fae2adfe98 83 Pfam PF14201 Domain of unknown function (DUF4318) 14 81 5.7E-10 T 28-03-2018 IPR025467 Protein of unknown function DUF4318 CPF12_RS03800 9fecf6b805f530f5bdbc0e5962bf07a3 219 Pfam PF01610 Transposase 1 213 4.9E-36 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS04025 9fecf6b805f530f5bdbc0e5962bf07a3 219 Pfam PF01610 Transposase 1 213 4.9E-36 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS07765 f321757fc8f5da77cf7a95fef9aceb43 82 Pfam PF04226 Transglycosylase associated protein 32 77 1.7E-12 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CPF12_RS05175 6c0d1ee591a6e0969cf23958dd668230 427 Pfam PF12704 MacB-like periplasmic core domain 27 212 5.4E-7 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CPF12_RS10830 c119f0fa2b3919151fcf3bc327a3c8c9 260 TIGRFAM TIGR03580 EF_0832: conserved hypothetical protein EF_0832/AHA_3913 4 257 1.7E-146 T 28-03-2018 IPR020042 Protein of unknown function DUF4311 CPF12_RS10830 c119f0fa2b3919151fcf3bc327a3c8c9 260 Pfam PF14188 Domain of unknown function (DUF4311) 26 238 8.2E-119 T 28-03-2018 IPR020042 Protein of unknown function DUF4311 CPF12_RS06935 95d92f6090783d26b9c7b9db3b4e56ad 147 SUPERFAMILY SSF52058 51 141 6.8E-6 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CPF12_RS06935 95d92f6090783d26b9c7b9db3b4e56ad 147 Pfam PF13306 Leucine rich repeats (6 copies) 30 143 1.3E-11 T 28-03-2018 IPR026906 Leucine rich repeat 5 CPF12_RS06935 95d92f6090783d26b9c7b9db3b4e56ad 147 Gene3D G3DSA:3.80.10.10 3 144 2.0E-7 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CPF12_RS12210 9d0ae607295ac00a712e200e63264ce0 181 Pfam PF03780 Asp23 family, cell envelope-related function 21 126 7.3E-33 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CPF12_RS02665 ec92a89d64f4480425a35629884ae585 370 Pfam PF06054 Competence protein CoiA-like family 1 333 3.2E-35 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like CPF12_RS01680 999276f100e09697cf72d3820fe32f17 109 Pfam PF00068 Phospholipase A2 31 84 2.4E-8 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CPF12_RS01680 999276f100e09697cf72d3820fe32f17 109 Gene3D G3DSA:1.20.90.10 13 105 1.6E-10 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CPF12_RS01680 999276f100e09697cf72d3820fe32f17 109 SUPERFAMILY SSF48619 28 88 3.93E-13 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CPF12_RS11710 06ad1ac7017df8a7f4e57d256bc9ff59 410 Pfam PF01139 tRNA-splicing ligase RtcB 30 410 1.9E-111 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CPF12_RS11710 06ad1ac7017df8a7f4e57d256bc9ff59 410 SUPERFAMILY SSF103365 6 410 4.97E-118 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CPF12_RS08060 89b994d87f36f0e5cd371bdc518a59db 243 Pfam PF02754 Cysteine-rich domain 3 84 8.0E-14 T 28-03-2018 IPR004017 Cysteine-rich domain CPF12_RS08060 89b994d87f36f0e5cd371bdc518a59db 243 Pfam PF02754 Cysteine-rich domain 132 215 3.1E-15 T 28-03-2018 IPR004017 Cysteine-rich domain CPF12_RS11700 4f1a04550f0682d94e2f0c33209208f5 325 Pfam PF13280 WYL domain 148 316 7.5E-11 T 28-03-2018 IPR026881 WYL domain CPF12_RS07090 289be20f3d07b87721b0df2defdda22e 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 106 2.5E-29 T 28-03-2018 CPF12_RS02525 5610f4782e72607d307ad9fa48b8e529 454 Pfam PF02386 Cation transport protein 36 435 9.6E-54 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CPF12_RS00865 1e05253530b882e8d4df296fbd2ed330 321 Gene3D G3DSA:3.90.550.10 1 196 2.4E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS00865 1e05253530b882e8d4df296fbd2ed330 321 Pfam PF00535 Glycosyl transferase family 2 5 165 5.2E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CPF12_RS00865 1e05253530b882e8d4df296fbd2ed330 321 SUPERFAMILY SSF53448 1 178 6.51E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CPF12_RS07525 40a210bc0c8f944618fa7247b200a087 374 Pfam PF00999 Sodium/hydrogen exchanger family 9 372 1.6E-77 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CPF12_RS07525 40a210bc0c8f944618fa7247b200a087 374 Gene3D G3DSA:1.20.91.10 222 305 5.9E-15 T 28-03-2018 CPF12_RS10265 c6b843ac25a1b0640837d73836f16f7f 371 SUPERFAMILY SSF51905 309 367 1.81E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS10265 c6b843ac25a1b0640837d73836f16f7f 371 SUPERFAMILY SSF51905 1 221 1.81E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS10265 c6b843ac25a1b0640837d73836f16f7f 371 SUPERFAMILY SSF54373 222 308 3.01E-10 T 28-03-2018 CPF12_RS10265 c6b843ac25a1b0640837d73836f16f7f 371 Gene3D G3DSA:3.50.50.60 1 368 9.0E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CPF12_RS10265 c6b843ac25a1b0640837d73836f16f7f 371 Pfam PF01266 FAD dependent oxidoreductase 3 348 4.9E-53 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CPF12_RS07230 27ad265099938148670197e1b741deee 73 Pfam PF11372 Domain of unknown function (DUF3173) 3 60 4.5E-22 T 28-03-2018 IPR021512 Protein of unknown function DUF3173 CPF12_RS06665 65cec99a449836fe2ca66309ca9ea8f0 294 PIRSF PIRSF003097 1 294 8.1E-84 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CPF12_RS06665 65cec99a449836fe2ca66309ca9ea8f0 294 Pfam PF02687 FtsX-like permease family 197 293 3.5E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS08325 9eb2b603378731b0ea29f3f50727a96f 237 Pfam PF13930 DNA/RNA non-specific endonuclease 96 220 6.0E-27 T 28-03-2018 CPF12_RS06600 c979d79d2857c3a5c1cd85dbb7072750 324 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 166 303 3.9E-24 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CPF12_RS10735 46e94c09e8883d015c4b428b6f8827ab 453 Pfam PF03611 PTS system sugar-specific permease component 12 406 4.0E-147 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CPF12_RS02120 6e32885b23e7eb91a5289f65e8e04f73 393 Pfam PF01098 Cell cycle protein 23 383 2.6E-96 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CPF12_RS02120 6e32885b23e7eb91a5289f65e8e04f73 393 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 340 364 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CPF12_RS08520 8229adbea7dbffa4867b491478b357b4 294 Pfam PF07905 Purine catabolism regulatory protein-like family 6 125 1.3E-17 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CPF12_RS03645 73ffae0768db58afda1c72775234f5a4 328 Pfam PF02698 DUF218 domain 158 305 2.3E-31 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CPF12_RS03645 73ffae0768db58afda1c72775234f5a4 328 Gene3D G3DSA:3.40.50.620 149 296 1.1E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CPF12_RS08900 2b08e4234b6a7d3c3b495038930d899e 1108 Gene3D G3DSA:2.60.40.10 1027 1098 4.6E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS08900 2b08e4234b6a7d3c3b495038930d899e 1108 Gene3D G3DSA:2.60.40.10 777 853 0.017 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS08900 2b08e4234b6a7d3c3b495038930d899e 1108 Gene3D G3DSA:2.60.40.10 856 944 2.3E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CPF12_RS05795 8af0d1a19dc61abbc46cfcf418c8af2f 124 Pfam PF04977 Septum formation initiator 46 121 1.7E-17 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CPF12_RS02925 c9481dc1b0e595a1f58f0743d7e23961 337 Pfam PF01384 Phosphate transporter family 22 326 9.3E-89 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CPF12_RS04400 b26d8e47634a54f5afe678e06ac0d9b8 138 Gene3D G3DSA:3.40.1440.10 23 137 5.3E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CPF12_RS07305 59fb8dc1764d092464f58dac4b4454ae 293 Pfam PF02361 Cobalt transport protein 15 212 5.5E-16 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CPF12_RS03555 38e2496446f512f7a8adec1ab4bd0104 298 Pfam PF15983 Domain of unknown function (DUF4767) 46 184 1.1E-41 T 28-03-2018 IPR031927 Domain of unknown function DUF4767 CPF12_RS06285 31987131efe2255cb6acb2bc15ef2da6 181 Pfam PF02632 BioY family 30 171 3.0E-34 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CPF12_RS06285 31987131efe2255cb6acb2bc15ef2da6 181 PIRSF PIRSF016661 1 180 8.4E-44 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CPF12_RS06930 121a8402138fb85b78261e2d558b9326 218 SUPERFAMILY SSF50978 39 178 2.5E-6 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CPF12_RS06750 3e9831b264e099135e20d0d41f8b135c 34 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 2 34 2.1E-13 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CPF12_RS03610 92a13f5dc12e696d29f0f62d97c8b0a1 380 Pfam PF01594 AI-2E family transporter 31 362 3.7E-73 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CPF12_RS02420 18b32f79a0e43f4570a0630c882844fe 309 Gene3D G3DSA:1.10.10.10 16 46 6.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CPF12_RS02420 18b32f79a0e43f4570a0630c882844fe 309 Pfam PF01610 Transposase 69 268 7.1E-35 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CPF12_RS02420 18b32f79a0e43f4570a0630c882844fe 309 Gene3D G3DSA:1.10.260.40 47 127 6.1E-4 T 28-03-2018 CPF12_RS06760 0042a0e2e17081469b32bc1f390198ca 79 Pfam PF04024 PspC domain 3 60 1.2E-21 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CPF12_RS11655 1d44e00aa1ecc0dfce404629fa408738 46 Pfam PF04604 Type-A lantibiotic 2 45 7.1E-26 T 28-03-2018 IPR007682 Lantibiotic, type A, Lactobacillales-type GO:0005576|GO:0042742 CPF12_RS02535 54acab671917d524f116af9359ada6a3 254 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 244 3.6E-86 T 28-03-2018 IPR022493 Integral membrane YkoY CPF12_RS02535 54acab671917d524f116af9359ada6a3 254 Pfam PF03741 Integral membrane protein TerC family 15 205 3.9E-51 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CPF12_RS03770 55eab1960fbd3e7170bd61f1394edc25 308 Pfam PF03773 Predicted permease 9 308 4.3E-77 T 28-03-2018 IPR005524 Predicted permease DUF318 CPF12_RS08885 48281f76c7b43e0728994382819ebd37 417 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 315 400 4.4E-11 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CPF12_RS04030 2278e05033ab2df2f969e4f97257a165 172 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 97 8.4E-8 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS02425 fe2eb1566daba780cd7f21d5c27862cf 108 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 49 97 6.9E-8 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CPF12_RS07725 159bf12694929575c03c620ff18663a8 278 Pfam PF06691 Protein of unknown function (DUF1189) 29 267 1.1E-8 T 28-03-2018 IPR009574 Protein of unknown function DUF1189 CPF12_RS10465 3bd16a1721b231332e34f5429e0d6693 693 SUPERFAMILY SSF49899 66 295 3.77E-19 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CPF12_RS10465 3bd16a1721b231332e34f5429e0d6693 693 Gene3D G3DSA:2.60.120.200 51 298 8.8E-27 T 28-03-2018 CPF12_RS10465 3bd16a1721b231332e34f5429e0d6693 693 Pfam PF00139 Legume lectin domain 70 170 3.6E-8 T 28-03-2018 IPR001220 Legume lectin domain GO:0030246 CPF12_RS05255 e720ea28cfb6c6ac8649cddf4627798c 487 Pfam PF05043 Mga helix-turn-helix domain 79 159 2.9E-15 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CPF12_RS04690 d67fb9aefa9510bb00972acf7a87a401 130 Pfam PF08349 Protein of unknown function (DUF1722) 15 124 1.4E-21 T 28-03-2018 IPR013560 Domain of unknown function DUF1722 CPF12_RS05680 28c139154d017fb5c699961701ddfb04 271 Pfam PF04468 PSP1 C-terminal conserved region 62 146 2.8E-28 T 28-03-2018 IPR007557 PSP1, C-terminal CPF12_RS03950 ec998f248ff0f0b277b0c8dbca570081 178 Pfam PF02417 Chromate transporter 5 171 1.4E-34 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CPF12_RS02615 47a2719061721b16d81d23e723184d00 219 Pfam PF02517 CAAX protease self-immunity 124 214 2.4E-11 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CPF12_RS08875 d7098d88b44744c9cf31c149da860344 475 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 118 460 3.1E-12 T 28-03-2018 CPF12_RS01890 2c7772bb8f74a538e9799a19ab47bccc 222 Pfam PF04172 LrgB-like family 11 222 2.9E-51 T 28-03-2018 IPR007300 CidB/LrgB family CPF12_RS10700 5fbabbb3a5e38c42a7e7546d0f5b1dca 100 Pfam PF02583 Metal-sensitive transcriptional repressor 17 93 4.9E-29 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CPF12_RS01740 8233e3320756f16a52ae89f4054082a1 168 Pfam PF02618 YceG-like family 105 166 1.6E-7 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CPF12_RS03295 689c7b96219c4869c0c6e23b04c79c5c 207 Gene3D G3DSA:3.20.20.380 1 207 5.0E-65 T 28-03-2018 CPF12_RS03295 689c7b96219c4869c0c6e23b04c79c5c 207 Pfam PF03932 CutC family 3 205 1.4E-62 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CPF12_RS03295 689c7b96219c4869c0c6e23b04c79c5c 207 SUPERFAMILY SSF110395 3 206 8.5E-52 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CPF12_RS00800 4ccd4038d337cd8b29ee4bca4f467141 197 Gene3D G3DSA:2.60.120.560 3 197 1.1E-14 T 28-03-2018 CPF12_RS04775 079079546e5d052104b8a420e1dcd2a2 150 Pfam PF11694 Protein of unknown function (DUF3290) 3 144 8.6E-49 T 28-03-2018 IPR021707 Protein of unknown function DUF3290 CPF12_RS03105 f48f6a1447e1656f25351e8601f5941a 133 Gene3D G3DSA:1.20.210.10 1 133 3.4E-6 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CPF12_RS03105 f48f6a1447e1656f25351e8601f5941a 133 Pfam PF11070 Protein of unknown function (DUF2871) 1 128 1.5E-47 T 28-03-2018 IPR021299 Protein of unknown function DUF2871 CPF12_RS03180 a806a3f7d5220bfe05cc35544ef612b0 377 Pfam PF07949 YbbR-like protein 53 133 2.4E-5 T 28-03-2018 IPR012505 YbbR-like CPF12_RS03180 a806a3f7d5220bfe05cc35544ef612b0 377 Pfam PF07949 YbbR-like protein 236 314 1.3E-11 T 28-03-2018 IPR012505 YbbR-like CPF12_RS03180 a806a3f7d5220bfe05cc35544ef612b0 377 Pfam PF07949 YbbR-like protein 152 227 6.3E-5 T 28-03-2018 IPR012505 YbbR-like CPF12_RS01495 f77a8c4fa1ec7c3db781c18b1a5320a2 124 Pfam PF03780 Asp23 family, cell envelope-related function 11 116 1.4E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CPF12_RS00125 92108560237c79c3f48e0d9c3e853a0b 127 Pfam PF13273 Protein of unknown function (DUF4064) 2 110 1.0E-8 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CPF12_RS08560 8256cfab511fc6edbfaabfea4acb7aec 363 Pfam PF02687 FtsX-like permease family 269 355 5.2E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CPF12_RS09850 66781264abe93e10f3ba65ffa61e6208 266 Pfam PF07285 Protein of unknown function (DUF1444) 6 264 4.3E-95 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CPF12_RS11580 d333803cf57b4a2450310476572c2428 88 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 20 85 3.8E-25 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CPF12_RS06885 e0f8f5bbde4de5137541bdac468a31f4 102 Pfam PF05154 TM2 domain 21 74 2.6E-16 T 28-03-2018 IPR007829 TM2 domain CPF12_RS08590 80ba537bc91a401ec210cb5a5e14c477 148 Pfam PF12821 Threonine/Serine exporter, ThrE 8 134 7.2E-33 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CPF12_RS06265 e4d7acec4b4158de389deb780340f5e8 70 Gene3D G3DSA:1.20.1070.10 1 69 8.6E-4 T 28-03-2018 CPF12_RS09135 13deb0c365a377d62855502ca86c21c3 64 Pfam PF14146 Domain of unknown function (DUF4305) 17 49 5.4E-11 T 28-03-2018 IPR025426 Protein of unknown function DUF4305 CPF12_RS01150 1678ea38d859ec8792a2ab2f38185217 286 Gene3D G3DSA:1.25.40.10 7 259 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CPF12_RS05290 14a9f5fdbfa4b55fe04cf03a77d2b8f3 79 Pfam PF00746 LPXTG cell wall anchor motif 33 63 5.5E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CPF12_RS07530 1698137f238e9712c35f5d5f46e5d74f 262 Pfam PF12730 ABC-2 family transporter protein 4 185 4.8E-17 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CPF12_RS06535 51d42f2f0f766a5049e4ebddb96953ce 360 Pfam PF00953 Glycosyl transferase family 4 70 225 8.3E-38 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CPF12_RS04250 b1ce1d3c2d9c54807e86228de48ca667 172 Pfam PF02378 Phosphotransferase system, EIIC 44 170 1.0E-18 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020