locus-tag	class	description
C6Y57_RS00045	COG1201	RNA secondary structure unwinding
C6Y57_RS00060	COG0730	response to heat
C6Y57_RS00070	COG0789	Transcriptional regulator
C6Y57_RS00075	COG1993	acr, cog1993
C6Y57_RS00095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6Y57_RS00110	COG1802	Transcriptional regulator
C6Y57_RS00125	COG0246	Mannitol dehydrogenase
C6Y57_RS00135	COG3842	ATPase activity
C6Y57_RS00140	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6Y57_RS00145	COG4208	sulfate ABC transporter
C6Y57_RS00150	COG2721	sulfolactate sulfo-lyase activity
C6Y57_RS00160	COG0747	negative chemotaxis
C6Y57_RS00165	COG0601	transmembrane transport
C6Y57_RS00170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6Y57_RS00190	COG0583	DNA-binding transcription factor activity
C6Y57_RS00210	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS00215	COG0183	Belongs to the thiolase family
C6Y57_RS00220	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6Y57_RS00220	COG1024	Enoyl-CoA hydratase
C6Y57_RS00245	COG0288	reversible hydration of carbon dioxide
C6Y57_RS00255	COG0747	negative chemotaxis
C6Y57_RS00265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6Y57_RS00270	COG0444	Belongs to the ABC transporter superfamily
C6Y57_RS00275	COG4172	Belongs to the ABC transporter superfamily
C6Y57_RS00295	COG0363	glucosamine-6-phosphate deaminase activity
C6Y57_RS00300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6Y57_RS00350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6Y57_RS00360	COG0174	glutamine synthetase
C6Y57_RS00375	COG0583	DNA-binding transcription factor activity
C6Y57_RS00395	COG1846	Transcriptional regulator
C6Y57_RS00425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6Y57_RS00430	COG1120	ATPase activity
C6Y57_RS00445	COG0251	oxidation-reduction process
C6Y57_RS00450	COG0395	ABC-type sugar transport system, permease component
C6Y57_RS00475	COG1737	Transcriptional regulator
C6Y57_RS00500	COG4176	ABC-type proline glycine betaine transport system permease component
C6Y57_RS00555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C6Y57_RS00560	COG0509	glycine decarboxylation via glycine cleavage system
C6Y57_RS00580	COG1522	sequence-specific DNA binding
C6Y57_RS00590	COG1840	ABC-type Fe3 transport system, periplasmic component
C6Y57_RS00610	COG3718	enzyme involved in inositol metabolism
C6Y57_RS00620	COG3962	Belongs to the TPP enzyme family
C6Y57_RS00635	COG0673	inositol 2-dehydrogenase activity
C6Y57_RS00650	COG0450	alkyl hydroperoxide reductase
C6Y57_RS00660	COG0477	Major facilitator Superfamily
C6Y57_RS00675	COG2132	Multicopper oxidase
C6Y57_RS00690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6Y57_RS00700	COG1840	ABC-type Fe3 transport system, periplasmic component
C6Y57_RS00735	COG1175	transmembrane transport
C6Y57_RS00740	COG0395	ABC-type sugar transport system, permease component
C6Y57_RS00745	COG3842	ATPase activity
C6Y57_RS00755	COG0477	Major facilitator Superfamily
C6Y57_RS00770	COG0248	Ppx GppA phosphatase
C6Y57_RS00775	COG1126	abc transporter atp-binding protein
C6Y57_RS00780	COG3485	protocatechuate 3,4-dioxygenase
C6Y57_RS00785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6Y57_RS00790	COG2267	carboxylic ester hydrolase activity
C6Y57_RS00795	COG0583	DNA-binding transcription factor activity
C6Y57_RS00810	COG1414	Transcriptional regulator
C6Y57_RS00820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6Y57_RS00850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6Y57_RS00855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6Y57_RS00875	COG2176	DNA-directed DNA polymerase activity
C6Y57_RS00920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6Y57_RS00960	COG0557	exoribonuclease II activity
C6Y57_RS00965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6Y57_RS00965	COG1754	DNA topoisomerase type I activity
C6Y57_RS00970	COG0758	DNA mediated transformation
C6Y57_RS00980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C6Y57_RS00990	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS01025	COG0187	DNA topoisomerase II activity
C6Y57_RS01030	COG0697	spore germination
C6Y57_RS01070	COG0785	Cytochrome C biogenesis protein
C6Y57_RS01090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6Y57_RS01095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6Y57_RS01100	COG0346	lactoylglutathione lyase activity
C6Y57_RS01125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6Y57_RS01130	COG1183	phosphatidylcholine synthase activity
C6Y57_RS01140	COG3845	ABC transporter
C6Y57_RS01145	COG4603	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS01180	COG1959	2 iron, 2 sulfur cluster binding
C6Y57_RS01185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6Y57_RS01210	COG2963	transposase activity
C6Y57_RS01215	COG3436	PFAM IS66 Orf2 family protein
C6Y57_RS01220	COG2433	Pfam Transposase IS66
C6Y57_RS01270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C6Y57_RS01310	COG0601	transmembrane transport
C6Y57_RS01315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6Y57_RS01320	COG4172	Belongs to the ABC transporter superfamily
C6Y57_RS01325	COG3145	DNA-N1-methyladenine dioxygenase activity
C6Y57_RS01335	COG0477	Major facilitator Superfamily
C6Y57_RS01375	COG0022	dehydrogenase e1 component
C6Y57_RS01395	COG0673	inositol 2-dehydrogenase activity
C6Y57_RS01400	COG0395	ABC-type sugar transport system, permease component
C6Y57_RS01405	COG1175	transmembrane transport
C6Y57_RS01420	COG2971	BadF BadG BcrA BcrD
C6Y57_RS01425	COG2188	Transcriptional regulator
C6Y57_RS01435	COG1294	oxidase, subunit
C6Y57_RS01440	COG1271	oxidase subunit
C6Y57_RS01445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6Y57_RS01450	COG4988	ABC transporter
C6Y57_RS01470	COG2212	antiporter activity
C6Y57_RS01475	COG1863	multisubunit Na H antiporter MnhE subunit
C6Y57_RS01480	COG0651	ATP synthesis coupled electron transport
C6Y57_RS01485	COG1006	Multisubunit Na H antiporter MnhC subunit
C6Y57_RS01490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6Y57_RS01490	COG2111	Na H antiporter
C6Y57_RS01505	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6Y57_RS01520	COG0156	8-amino-7-oxononanoate synthase activity
C6Y57_RS01530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6Y57_RS01535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6Y57_RS01555	COG1115	amino acid carrier protein
C6Y57_RS01570	COG1252	NADH dehydrogenase
C6Y57_RS01600	COG2205	protein histidine kinase activity
C6Y57_RS01635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6Y57_RS01645	COG0842	Transport permease protein
C6Y57_RS01690	COG0640	Transcriptional regulator
C6Y57_RS01695	COG2354	Protein conserved in bacteria
C6Y57_RS01700	COG0242	peptide deformylase activity
C6Y57_RS01705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6Y57_RS01720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6Y57_RS01730	COG0183	Belongs to the thiolase family
C6Y57_RS01735	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS01740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6Y57_RS01745	COG0583	DNA-binding transcription factor activity
C6Y57_RS01750	COG2814	Major facilitator Superfamily
C6Y57_RS01760	COG2233	PERMEase
C6Y57_RS01765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6Y57_RS01780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C6Y57_RS01785	COG4310	Domain of unknown function (DUF2172)
C6Y57_RS01790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6Y57_RS01805	COG0438	transferase activity, transferring glycosyl groups
C6Y57_RS01825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6Y57_RS01850	COG0110	maltose O-acetyltransferase activity
C6Y57_RS01855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6Y57_RS01880	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6Y57_RS01885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6Y57_RS01900	COG2197	response regulator
C6Y57_RS01925	COG2186	Transcriptional regulator
C6Y57_RS01945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6Y57_RS01990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6Y57_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS02020	COG0604	alcohol dehydrogenase
C6Y57_RS02020	COG3321	synthase
C6Y57_RS02025	COG1802	Transcriptional regulator
C6Y57_RS02030	COG2124	cytochrome p450
C6Y57_RS02035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6Y57_RS02040	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C6Y57_RS02070	COG3077	Addiction module antitoxin, RelB DinJ family
C6Y57_RS02135	COG5314	conjugation
C6Y57_RS02165	COG0582	viral genome integration into host DNA
C6Y57_RS02190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C6Y57_RS02190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6Y57_RS02205	COG0583	DNA-binding transcription factor activity
C6Y57_RS02210	COG3258	Cytochrome c
C6Y57_RS02230	COG3191	aminopeptidase activity
C6Y57_RS02235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6Y57_RS02255	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6Y57_RS02325	COG1177	transmembrane transport
C6Y57_RS02330	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6Y57_RS02335	COG3842	ATPase activity
C6Y57_RS02360	COG2894	cell division
C6Y57_RS02390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6Y57_RS02395	COG2814	Major facilitator Superfamily
C6Y57_RS02405	COG0673	inositol 2-dehydrogenase activity
C6Y57_RS02430	COG1653	transport
C6Y57_RS02435	COG1609	Transcriptional regulator
C6Y57_RS02445	COG2223	nitrite transmembrane transporter activity
C6Y57_RS02450	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6Y57_RS02455	COG1140	nitrate reductase beta subunit
C6Y57_RS02460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6Y57_RS02465	COG2181	nitrate reductase activity
C6Y57_RS02495	COG0826	peptidase U32
C6Y57_RS02515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6Y57_RS02540	COG1477	protein flavinylation
C6Y57_RS02580	COG4178	(ABC) transporter
C6Y57_RS02590	COG5654	RES domain protein
C6Y57_RS02595	COG1069	ribulokinase activity
C6Y57_RS02610	COG4214	carbohydrate transport
C6Y57_RS02640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6Y57_RS02670	COG2151	metal-sulfur cluster biosynthetic enzyme
C6Y57_RS02695	COG0714	Associated with various cellular activities
C6Y57_RS02700	COG3256	nitric oxide reductase
C6Y57_RS02715	COG1845	cytochrome c oxidase, subunit III
C6Y57_RS02730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6Y57_RS02735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6Y57_RS02760	COG1477	protein flavinylation
C6Y57_RS02805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6Y57_RS02810	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6Y57_RS02815	COG1024	Enoyl-CoA hydratase
C6Y57_RS02825	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS02855	COG1519	Transferase
C6Y57_RS02875	COG0312	modulator of DNA gyrase
C6Y57_RS02880	COG0475	glutathione-regulated potassium exporter activity
C6Y57_RS02880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6Y57_RS02890	COG0612	Peptidase, M16
C6Y57_RS02895	COG0612	Peptidase, M16
C6Y57_RS02900	COG0612	Peptidase, M16
C6Y57_RS02905	COG0742	ribosomal rna small subunit methyltransferase
C6Y57_RS02910	COG1187	pseudouridine synthase activity
C6Y57_RS02915	COG0590	tRNA wobble adenosine to inosine editing
C6Y57_RS02935	COG0196	riboflavin kinase activity
C6Y57_RS02975	COG2259	Doxx family
C6Y57_RS03010	COG2818	Glycosylase
C6Y57_RS03015	COG1376	ErfK ybiS ycfS ynhG family protein
C6Y57_RS03015	COG1388	LysM domain
C6Y57_RS03025	COG0656	L-ascorbic acid biosynthetic process
C6Y57_RS03030	COG0247	lactate metabolic process
C6Y57_RS03040	COG0277	FAD linked oxidase domain protein
C6Y57_RS03045	COG0583	DNA-binding transcription factor activity
C6Y57_RS03050	COG2186	Transcriptional regulator
C6Y57_RS03085	COG3038	cytochrome b561
C6Y57_RS03100	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
C6Y57_RS03110	COG0583	DNA-binding transcription factor activity
C6Y57_RS03130	COG1338	Plays a role in the flagellum-specific transport system
C6Y57_RS03150	COG1706	bacterial-type flagellum-dependent cell motility
C6Y57_RS03155	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C6Y57_RS03160	COG4786	Flagellar basal body rod
C6Y57_RS03170	COG1558	bacterial-type flagellum-dependent cell motility
C6Y57_RS03175	COG1815	bacterial-type flagellum-dependent cell motility
C6Y57_RS03185	COG3395	kinase activity
C6Y57_RS03190	COG3622	Belongs to the hyi family
C6Y57_RS03195	COG1349	DNA-binding transcription factor activity
C6Y57_RS03200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6Y57_RS03205	COG0235	Class ii aldolase
C6Y57_RS03210	COG2271	Major facilitator Superfamily
C6Y57_RS03215	COG2963	transposase activity
C6Y57_RS03230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C6Y57_RS03240	COG0463	Glycosyl transferase, family 2
C6Y57_RS03255	COG0671	phosphoesterase, PA-phosphatase related
C6Y57_RS03265	COG1157	protein secretion by the type III secretion system
C6Y57_RS03270	COG4786	Flagellar basal body rod
C6Y57_RS03280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6Y57_RS03295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6Y57_RS03300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6Y57_RS03305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6Y57_RS03310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6Y57_RS03325	COG1309	transcriptional regulator
C6Y57_RS03365	COG0673	inositol 2-dehydrogenase activity
C6Y57_RS03400	COG3206	protein involved in exopolysaccharide biosynthesis
C6Y57_RS03400	COG0489	protein tyrosine kinase activity
C6Y57_RS03410	COG0154	amidase activity
C6Y57_RS03415	COG0583	DNA-binding transcription factor activity
C6Y57_RS03425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6Y57_RS03450	COG4149	molybdate abc transporter
C6Y57_RS03455	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6Y57_RS03475	COG0800	Aldolase
C6Y57_RS03480	COG3108	Peptidase M15
C6Y57_RS03510	COG5310	Homospermidine synthase
C6Y57_RS03525	COG0330	HflC and HflK could
C6Y57_RS03545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6Y57_RS03550	COG2951	lytic endotransglycosylase activity
C6Y57_RS03625	COG1113	amino acid transport
C6Y57_RS03635	COG0070	glutamate synthase
C6Y57_RS03635	COG0069	glutamate synthase activity
C6Y57_RS03635	COG0067	glutamate synthase
C6Y57_RS03650	COG0071	Belongs to the small heat shock protein (HSP20) family
C6Y57_RS03680	COG0483	inositol monophosphate 1-phosphatase activity
C6Y57_RS03700	COG4566	intracellular signal transduction
C6Y57_RS03705	COG4191	Histidine kinase
C6Y57_RS03740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6Y57_RS03745	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6Y57_RS03750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6Y57_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS03795	COG2186	Transcriptional regulator
C6Y57_RS03800	COG4944	Protein of unknown function (DUF1109)
C6Y57_RS03805	COG1595	DNA-templated transcription, initiation
C6Y57_RS03820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C6Y57_RS03825	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6Y57_RS03825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6Y57_RS03835	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6Y57_RS03840	COG3433	isochorismatase activity
C6Y57_RS03840	COG1535	isochorismatase
C6Y57_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS03860	COG1744	ABC transporter substrate-binding protein PnrA-like
C6Y57_RS03875	COG1079	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS03880	COG1957	nucleoside hydrolase
C6Y57_RS03885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6Y57_RS03895	COG1414	Transcriptional regulator
C6Y57_RS03905	COG1192	Involved in chromosome partitioning
C6Y57_RS03920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6Y57_RS04000	COG3842	ATPase activity
C6Y57_RS04005	COG1175	transmembrane transport
C6Y57_RS04010	COG3833	ABC-type maltose transport systems, permease component
C6Y57_RS04015	COG1653	transport
C6Y57_RS04020	COG2188	Transcriptional regulator
C6Y57_RS04040	COG1129	ABC transporter
C6Y57_RS04055	COG1228	amidohydrolase
C6Y57_RS04060	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS04065	COG0531	amino acid
C6Y57_RS04090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6Y57_RS04095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6Y57_RS04100	COG1846	Transcriptional regulator
C6Y57_RS04120	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6Y57_RS04125	COG3971	2-oxopent-4-enoate hydratase activity
C6Y57_RS04135	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C6Y57_RS04155	COG4214	carbohydrate transport
C6Y57_RS04165	COG4213	ABC transporter substrate-binding protein
C6Y57_RS04180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6Y57_RS04200	COG1360	Flagellar Motor Protein
C6Y57_RS04250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C6Y57_RS04260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6Y57_RS04295	COG0735	belongs to the Fur family
C6Y57_RS04300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6Y57_RS04315	COG0523	cobalamin synthesis protein
C6Y57_RS04320	COG1959	2 iron, 2 sulfur cluster binding
C6Y57_RS04325	COG2971	BadF BadG BcrA BcrD
C6Y57_RS04375	COG0277	FAD linked oxidase domain protein
C6Y57_RS04385	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6Y57_RS04395	COG3395	kinase activity
C6Y57_RS04400	COG0235	Class ii aldolase
C6Y57_RS04415	COG3842	ATPase activity
C6Y57_RS04425	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6Y57_RS04440	COG0154	amidase activity
C6Y57_RS04445	COG3386	PFAM SMP-30 Gluconolaconase
C6Y57_RS04450	COG4608	Belongs to the ABC transporter superfamily
C6Y57_RS04455	COG0444	Belongs to the ABC transporter superfamily
C6Y57_RS04465	COG0601	transmembrane transport
C6Y57_RS04515	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS04525	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6Y57_RS04530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6Y57_RS04550	COG0601	transmembrane transport
C6Y57_RS04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6Y57_RS04560	COG0444	Belongs to the ABC transporter superfamily
C6Y57_RS04565	COG4608	Belongs to the ABC transporter superfamily
C6Y57_RS04570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6Y57_RS04620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C6Y57_RS04625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6Y57_RS04630	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C6Y57_RS04640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6Y57_RS04665	COG0778	Nitroreductase
C6Y57_RS04675	COG1228	amidohydrolase
C6Y57_RS04695	COG1132	(ABC) transporter
C6Y57_RS04720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6Y57_RS04755	COG2827	Endonuclease containing a URI domain
C6Y57_RS04770	COG0242	peptide deformylase activity
C6Y57_RS04820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C6Y57_RS04845	COG0251	oxidation-reduction process
C6Y57_RS04865	COG2814	Major facilitator Superfamily
C6Y57_RS04870	COG1802	Transcriptional regulator
C6Y57_RS04895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6Y57_RS04900	COG0444	Belongs to the ABC transporter superfamily
C6Y57_RS04905	COG4608	Belongs to the ABC transporter superfamily
C6Y57_RS04910	COG0154	amidase activity
C6Y57_RS04915	COG2176	DNA-directed DNA polymerase activity
C6Y57_RS04920	COG0579	oxidoreductase
C6Y57_RS04925	COG3706	GGDEF domain
C6Y57_RS04965	COG1879	ABC-type sugar transport system periplasmic component
C6Y57_RS04970	COG1129	ABC transporter
C6Y57_RS04980	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS04985	COG0251	oxidation-reduction process
C6Y57_RS04995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C6Y57_RS05000	COG0400	carboxylic ester hydrolase activity
C6Y57_RS05010	COG0523	cobalamin synthesis protein
C6Y57_RS05030	COG1609	Transcriptional regulator
C6Y57_RS05035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6Y57_RS05040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6Y57_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS05050	COG5001	Diguanylate cyclase
C6Y57_RS05130	COG2011	ABC-type metal ion transport system permease component
C6Y57_RS05195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6Y57_RS05205	COG0028	Belongs to the TPP enzyme family
C6Y57_RS05215	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS05230	COG0129	dihydroxy-acid dehydratase activity
C6Y57_RS05235	COG3734	2-keto-3-deoxy-galactonokinase
C6Y57_RS05240	COG0800	Aldolase
C6Y57_RS05245	COG4213	ABC transporter substrate-binding protein
C6Y57_RS05250	COG1129	ABC transporter
C6Y57_RS05255	COG4214	carbohydrate transport
C6Y57_RS05290	COG0402	S-adenosylhomocysteine deaminase activity
C6Y57_RS05300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6Y57_RS05320	COG1522	sequence-specific DNA binding
C6Y57_RS05335	COG0243	molybdopterin cofactor binding
C6Y57_RS05355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6Y57_RS05365	COG2188	Transcriptional regulator
C6Y57_RS05375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6Y57_RS05395	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS05415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6Y57_RS05420	COG2183	response to ionizing radiation
C6Y57_RS05425	COG0640	Transcriptional regulator
C6Y57_RS05430	COG1902	pentaerythritol trinitrate reductase activity
C6Y57_RS05440	COG0010	Belongs to the arginase family
C6Y57_RS05495	COG2169	Transcriptional regulator
C6Y57_RS05495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6Y57_RS05510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6Y57_RS05515	COG1846	Transcriptional regulator
C6Y57_RS05520	COG1764	response to oxidative stress
C6Y57_RS05560	COG0339	signal peptide processing
C6Y57_RS05570	COG2239	Acts as a magnesium transporter
C6Y57_RS05575	COG1217	gtp-binding protein TYPA
C6Y57_RS05610	COG1349	DNA-binding transcription factor activity
C6Y57_RS05645	COG1129	ABC transporter
C6Y57_RS05650	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS05665	COG1349	DNA-binding transcription factor activity
C6Y57_RS05675	COG0546	phosphoglycolate phosphatase activity
C6Y57_RS05675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C6Y57_RS05690	COG1088	dTDP-glucose 4,6-dehydratase activity
C6Y57_RS05730	COG3586	endonuclease activity
C6Y57_RS05740	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C6Y57_RS05780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6Y57_RS05785	COG0006	proline dipeptidase activity
C6Y57_RS05795	COG1566	PFAM secretion protein HlyD family protein
C6Y57_RS05800	COG2814	Major facilitator Superfamily
C6Y57_RS05805	COG0427	acetyl-CoA hydrolase
C6Y57_RS05820	COG2897	thiosulfate sulfurtransferase activity
C6Y57_RS05825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6Y57_RS05830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6Y57_RS05835	COG0513	Belongs to the DEAD box helicase family
C6Y57_RS05840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6Y57_RS05860	COG1058	Belongs to the CinA family
C6Y57_RS05860	COG1546	Belongs to the CinA family
C6Y57_RS05900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6Y57_RS05915	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
C6Y57_RS05940	COG3106	COG3106 Predicted ATPase
C6Y57_RS05955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6Y57_RS05965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6Y57_RS05980	COG0633	Ferredoxin
C6Y57_RS06010	COG1127	ABC transporter
C6Y57_RS06020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6Y57_RS06025	COG4948	Mandelate Racemase Muconate Lactonizing
C6Y57_RS06035	COG0280	phosphate acetyltransferase
C6Y57_RS06035	COG0281	malic enzyme
C6Y57_RS06055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6Y57_RS06060	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C6Y57_RS06080	COG0546	phosphoglycolate phosphatase activity
C6Y57_RS06090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6Y57_RS06090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6Y57_RS06095	COG0347	Belongs to the P(II) protein family
C6Y57_RS06100	COG0174	glutamine synthetase
C6Y57_RS06135	COG0084	hydrolase, TatD family'
C6Y57_RS06165	COG1393	Belongs to the ArsC family
C6Y57_RS06300	COG2989	Protein conserved in bacteria
C6Y57_RS06360	COG0625	glutathione transferase activity
C6Y57_RS06365	COG2084	Dehydrogenase
C6Y57_RS06400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C6Y57_RS06420	COG0316	Belongs to the HesB IscA family
C6Y57_RS06425	COG0513	Belongs to the DEAD box helicase family
C6Y57_RS06445	COG2151	metal-sulfur cluster biosynthetic enzyme
C6Y57_RS06450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6Y57_RS06455	COG0719	Fe-S assembly protein
C6Y57_RS06460	COG0396	ATPase activity
C6Y57_RS06465	COG0719	Fe-S assembly protein
C6Y57_RS06475	COG2945	thiolester hydrolase activity
C6Y57_RS06500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6Y57_RS06505	COG2833	Protein of unknown function (DUF455)
C6Y57_RS06530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6Y57_RS06535	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6Y57_RS06545	COG1530	ribonuclease E activity
C6Y57_RS06550	COG0436	Aminotransferase
C6Y57_RS06555	COG0501	Belongs to the peptidase M48B family
C6Y57_RS06570	COG0511	ligase activity, forming carbon-carbon bonds
C6Y57_RS06575	COG0439	Biotin carboxylase
C6Y57_RS06585	COG4765	Protein conserved in bacteria
C6Y57_RS06605	COG0544	peptidyl-prolyl cis-trans isomerase activity
C6Y57_RS06655	COG1862	Preprotein translocase
C6Y57_RS06675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C6Y57_RS06690	COG0805	protein transport
C6Y57_RS06695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C6Y57_RS06705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C6Y57_RS06710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C6Y57_RS06715	COG1472	Belongs to the glycosyl hydrolase 3 family
C6Y57_RS06735	COG0316	Belongs to the HesB IscA family
C6Y57_RS06765	COG1573	uracil-dna glycosylase
C6Y57_RS06770	COG1522	sequence-specific DNA binding
C6Y57_RS06795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6Y57_RS06805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6Y57_RS06810	COG3454	Phosphonate metabolism
C6Y57_RS06815	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C6Y57_RS06820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6Y57_RS06840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6Y57_RS06845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6Y57_RS06850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6Y57_RS06870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6Y57_RS06875	COG2514	catechol 2,3-dioxygenase activity
C6Y57_RS06905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6Y57_RS06945	COG2814	Major facilitator Superfamily
C6Y57_RS06950	COG0483	inositol monophosphate 1-phosphatase activity
C6Y57_RS07005	COG0346	lactoylglutathione lyase activity
C6Y57_RS07020	COG1007	ATP synthesis coupled electron transport
C6Y57_RS07060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C6Y57_RS07065	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C6Y57_RS07085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6Y57_RS07160	COG0010	Belongs to the arginase family
C6Y57_RS07250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6Y57_RS07255	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C6Y57_RS07275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6Y57_RS07275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6Y57_RS07290	COG2989	Protein conserved in bacteria
C6Y57_RS07310	COG0113	porphobilinogen synthase activity
C6Y57_RS07325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6Y57_RS07345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6Y57_RS07355	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6Y57_RS07370	COG1126	abc transporter atp-binding protein
C6Y57_RS07375	COG0765	amino acid transport
C6Y57_RS07380	COG4597	amino acid ABC transporter
C6Y57_RS07390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6Y57_RS07405	COG0626	cystathionine gamma-synthase activity
C6Y57_RS07520	COG1620	l-lactate permease
C6Y57_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS07550	COG0628	permease
C6Y57_RS07565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6Y57_RS07580	COG0243	molybdopterin cofactor binding
C6Y57_RS07590	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6Y57_RS07625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6Y57_RS07630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6Y57_RS07635	COG0314	molybdopterin synthase activity
C6Y57_RS07655	COG0488	(ABC) transporter
C6Y57_RS07690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6Y57_RS07695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6Y57_RS07700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C6Y57_RS07710	COG0739	heme binding
C6Y57_RS07720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C6Y57_RS07755	COG0494	nUDIX hydrolase
C6Y57_RS07775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C6Y57_RS07785	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C6Y57_RS07810	COG0681	Belongs to the peptidase S26 family
C6Y57_RS07825	COG2207	Transcriptional regulator
C6Y57_RS07830	COG2223	nitrite transmembrane transporter activity
C6Y57_RS07840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6Y57_RS07880	COG0741	lytic transglycosylase activity
C6Y57_RS07885	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C6Y57_RS07885	COG3743	rRNA binding
C6Y57_RS07915	COG4974	Belongs to the 'phage' integrase family
C6Y57_RS07920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C6Y57_RS07955	COG0625	glutathione transferase activity
C6Y57_RS07960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6Y57_RS07975	COG1573	uracil-dna glycosylase
C6Y57_RS07990	COG0308	aminopeptidase N
C6Y57_RS07995	COG2205	protein histidine kinase activity
C6Y57_RS07995	COG2202	Pas domain
C6Y57_RS08025	COG3088	subunit of a heme lyase
C6Y57_RS08030	COG1138	Cytochrome C-type biogenesis protein
C6Y57_RS08040	COG4235	cytochrome complex assembly
C6Y57_RS08140	COG4695	Portal protein
C6Y57_RS08155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6Y57_RS08185	COG2205	protein histidine kinase activity
C6Y57_RS08195	COG2166	iron-sulfur cluster assembly
C6Y57_RS08200	COG0154	amidase activity
C6Y57_RS08210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C6Y57_RS08220	COG4957	zinc ion binding
C6Y57_RS08240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6Y57_RS08255	COG1376	ErfK ybiS ycfS ynhG family protein
C6Y57_RS08260	COG0433	COG0433 Predicted ATPase
C6Y57_RS08270	COG2807	transmembrane transport
C6Y57_RS08275	COG2186	Transcriptional regulator
C6Y57_RS08285	COG2336	PFAM SpoVT AbrB
C6Y57_RS08295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6Y57_RS08335	COG1070	Carbohydrate kinase
C6Y57_RS08345	COG0673	inositol 2-dehydrogenase activity
C6Y57_RS08355	COG1879	ABC-type sugar transport system periplasmic component
C6Y57_RS08360	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS08365	COG1129	ABC transporter
C6Y57_RS08380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C6Y57_RS08380	COG0438	transferase activity, transferring glycosyl groups
C6Y57_RS08385	COG2942	2-epimerase
C6Y57_RS08390	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C6Y57_RS08390	COG0662	Cupin 2, conserved barrel domain protein
C6Y57_RS08410	COG3293	Transposase
C6Y57_RS08415	COG2801	Transposase and inactivated derivatives
C6Y57_RS08420	COG2801	Transposase and inactivated derivatives
C6Y57_RS08455	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C6Y57_RS08540	COG1268	BioY protein
C6Y57_RS08570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6Y57_RS08570	COG0574	Belongs to the PEP-utilizing enzyme family
C6Y57_RS08585	COG1196	nuclear chromosome segregation
C6Y57_RS08605	COG1194	a g-specific adenine glycosylase
C6Y57_RS08625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6Y57_RS08635	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6Y57_RS08655	COG0612	Peptidase, M16
C6Y57_RS08660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6Y57_RS08680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6Y57_RS08680	COG0678	peroxiredoxin activity
C6Y57_RS08730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6Y57_RS08735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6Y57_RS08745	COG0312	modulator of DNA gyrase
C6Y57_RS08750	COG0194	GDP metabolic process
C6Y57_RS08755	COG1561	YicC-like family, N-terminal region
C6Y57_RS08765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6Y57_RS08775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6Y57_RS08800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6Y57_RS08835	COG0305	Participates in initiation and elongation during chromosome replication
C6Y57_RS08855	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6Y57_RS08860	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS08865	COG1183	phosphatidylcholine synthase activity
C6Y57_RS08875	COG5265	(ABC) transporter
C6Y57_RS08900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C6Y57_RS08910	COG1741	Belongs to the pirin family
C6Y57_RS08930	COG1722	exodeoxyribonuclease VII activity
C6Y57_RS08935	COG0123	including yeast histone deacetylase and acetoin utilization protein
C6Y57_RS08940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6Y57_RS08940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C6Y57_RS08965	COG1278	Cold shock
C6Y57_RS08980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6Y57_RS08985	COG0484	heat shock protein binding
C6Y57_RS09000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C6Y57_RS09015	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS09050	COG0009	L-threonylcarbamoyladenylate synthase
C6Y57_RS09055	COG0751	glycine-tRNA ligase activity
C6Y57_RS09070	COG0142	geranyltranstransferase activity
C6Y57_RS09175	COG3773	Cell wall hydrolase
C6Y57_RS09180	COG0443	Heat shock 70 kDa protein
C6Y57_RS09200	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6Y57_RS09215	COG1393	Belongs to the ArsC family
C6Y57_RS09220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6Y57_RS09220	COG2169	Transcriptional regulator
C6Y57_RS09225	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS09230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6Y57_RS09230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C6Y57_RS09290	COG0402	S-adenosylhomocysteine deaminase activity
C6Y57_RS09300	COG0583	DNA-binding transcription factor activity
C6Y57_RS09310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C6Y57_RS09315	COG2080	2 iron, 2 sulfur cluster binding
C6Y57_RS09325	COG3648	Uricase
C6Y57_RS09325	COG3195	allantoin biosynthetic process
C6Y57_RS09330	COG3257	ureidoglycine aminohydrolase activity
C6Y57_RS09335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C6Y57_RS09340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C6Y57_RS09390	COG0019	diaminopimelate decarboxylase activity
C6Y57_RS09430	COG1346	cytolysis
C6Y57_RS09435	COG1380	Effector of murein hydrolase LrgA
C6Y57_RS09440	COG0583	DNA-binding transcription factor activity
C6Y57_RS09465	COG0156	8-amino-7-oxononanoate synthase activity
C6Y57_RS09475	COG0784	Response regulator, receiver
C6Y57_RS09475	COG2205	protein histidine kinase activity
C6Y57_RS09475	COG2198	Histidine kinase
C6Y57_RS09505	COG0534	Mate efflux family protein
C6Y57_RS09525	COG0717	Belongs to the dCTP deaminase family
C6Y57_RS09540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C6Y57_RS09550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6Y57_RS09565	COG5002	protein histidine kinase activity
C6Y57_RS09570	COG2326	polyphosphate kinase activity
C6Y57_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
C6Y57_RS09635	COG0493	'glutamate synthase
C6Y57_RS09645	COG0494	nUDIX hydrolase
C6Y57_RS09650	COG1309	transcriptional regulator
C6Y57_RS09665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6Y57_RS09670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6Y57_RS09680	COG4191	Histidine kinase
C6Y57_RS09755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6Y57_RS09765	COG3617	BRO family, N-terminal domain
C6Y57_RS09775	COG3617	BRO family, N-terminal domain
C6Y57_RS09815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6Y57_RS09830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C6Y57_RS09855	COG4948	Mandelate Racemase Muconate Lactonizing
C6Y57_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS09875	COG3254	rhamnose metabolic process
C6Y57_RS09880	COG4948	Mandelate Racemase Muconate Lactonizing
C6Y57_RS09885	COG3842	ATPase activity
C6Y57_RS09890	COG0395	ABC-type sugar transport system, permease component
C6Y57_RS09895	COG1175	transmembrane transport
C6Y57_RS09905	COG1414	Transcriptional regulator
C6Y57_RS09920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C6Y57_RS09920	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6Y57_RS09935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6Y57_RS09945	COG1732	Glycine betaine
C6Y57_RS09950	COG1174	glycine betaine transport
C6Y57_RS09955	COG1125	glycine betaine transport
C6Y57_RS09960	COG1174	glycine betaine transport
C6Y57_RS09975	COG5001	Diguanylate cyclase
C6Y57_RS09980	COG0351	phosphomethylpyrimidine kinase
C6Y57_RS10005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6Y57_RS10010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6Y57_RS10015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6Y57_RS10020	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS10075	COG2197	response regulator
C6Y57_RS10090	COG1218	3'(2'),5'-bisphosphate nucleotidase
C6Y57_RS10110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6Y57_RS10115	COG2197	response regulator
C6Y57_RS10140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6Y57_RS10155	COG0175	sulfate reduction
C6Y57_RS10160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6Y57_RS10170	COG1648	precorrin-2 dehydrogenase activity
C6Y57_RS10170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C6Y57_RS10180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6Y57_RS10185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6Y57_RS10190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C6Y57_RS10225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6Y57_RS10255	COG0071	Belongs to the small heat shock protein (HSP20) family
C6Y57_RS10265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6Y57_RS10270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6Y57_RS10280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6Y57_RS10285	COG1137	ATPase activity
C6Y57_RS10290	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6Y57_RS10300	COG0616	signal peptide processing
C6Y57_RS10315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C6Y57_RS10315	COG0116	Belongs to the methyltransferase superfamily
C6Y57_RS10320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6Y57_RS10345	COG0281	malic enzyme
C6Y57_RS10345	COG0280	phosphate acetyltransferase
C6Y57_RS10355	COG0728	peptidoglycan biosynthetic process
C6Y57_RS10360	COG0180	Tryptophanyl-tRNA synthetase
C6Y57_RS10370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C6Y57_RS10375	COG1388	LysM domain
C6Y57_RS10375	COG1376	ErfK ybiS ycfS ynhG family protein
C6Y57_RS10385	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C6Y57_RS10410	COG1643	Atp-dependent helicase
C6Y57_RS10415	COG1643	Atp-dependent helicase
C6Y57_RS10430	COG2153	protein acetylation
C6Y57_RS10440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C6Y57_RS10455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6Y57_RS10455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6Y57_RS10465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6Y57_RS10470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6Y57_RS10485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6Y57_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS10500	COG2226	methyltransferase
C6Y57_RS10505	COG0384	phenazine biosynthesis protein PhzF
C6Y57_RS10515	COG3459	Glycosyltransferase 36 associated
C6Y57_RS10520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6Y57_RS10525	COG4208	sulfate ABC transporter
C6Y57_RS10535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6Y57_RS10580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6Y57_RS10590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6Y57_RS10595	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6Y57_RS10610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6Y57_RS10630	COG0670	Belongs to the BI1 family
C6Y57_RS10640	COG4181	ATPase activity
C6Y57_RS10650	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6Y57_RS10655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6Y57_RS10665	COG3339	Conserved Protein
C6Y57_RS10730	COG1272	protein, Hemolysin III
C6Y57_RS10760	COG1072	(Pantothenic acid kinase))
C6Y57_RS10765	COG1073	alpha beta
C6Y57_RS10780	COG0033	Phosphoglucomutase
C6Y57_RS10790	COG0489	protein tyrosine kinase activity
C6Y57_RS10795	COG0346	lactoylglutathione lyase activity
C6Y57_RS10835	COG1376	ErfK ybiS ycfS ynhG family protein
C6Y57_RS10860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6Y57_RS10865	COG1845	cytochrome c oxidase, subunit III
C6Y57_RS10870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6Y57_RS10875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6Y57_RS10885	COG3474	cytochrome
C6Y57_RS10895	COG0077	Prephenate dehydratase
C6Y57_RS10895	COG1605	Chorismate mutase
C6Y57_RS10900	COG2816	NAD+ diphosphatase activity
C6Y57_RS10915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6Y57_RS10930	COG2951	lytic endotransglycosylase activity
C6Y57_RS10940	COG0583	DNA-binding transcription factor activity
C6Y57_RS10945	COG2855	membrane
C6Y57_RS10950	COG0539	negative regulation of cytoplasmic translation
C6Y57_RS10990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6Y57_RS10995	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS11000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6Y57_RS11015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6Y57_RS11050	COG4166	transmembrane transport
C6Y57_RS11060	COG4174	ABC transporter (Permease)
C6Y57_RS11065	COG4239	(ABC) transporter, permease
C6Y57_RS11070	COG4172	Belongs to the ABC transporter superfamily
C6Y57_RS11075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6Y57_RS11110	COG1024	Enoyl-CoA hydratase
C6Y57_RS11125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C6Y57_RS11135	COG0791	NLP P60 protein
C6Y57_RS11175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6Y57_RS11180	COG2813	Specifically methylates the guanine in position
C6Y57_RS11220	COG0195	Participates in both transcription termination and antitermination
C6Y57_RS11220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C6Y57_RS11235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C6Y57_RS11240	COG1396	sequence-specific DNA binding
C6Y57_RS11250	COG4535	Mg2 and Co2 transporter CorC
C6Y57_RS11275	COG0456	acetyltransferase
C6Y57_RS11285	COG0783	Belongs to the Dps family
C6Y57_RS11290	COG2309	aminopeptidase activity
C6Y57_RS11300	COG3773	Cell wall hydrolase
C6Y57_RS11305	COG0745	RESPONSE REGULATOR receiver
C6Y57_RS11310	COG0704	Plays a role in the regulation of phosphate uptake
C6Y57_RS11315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6Y57_RS11325	COG0573	inorganic phosphate transmembrane transporter activity
C6Y57_RS11330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6Y57_RS11335	COG2832	Protein of unknown function (DUF454)
C6Y57_RS11345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6Y57_RS11355	COG0606	chelatase, subunit chli
C6Y57_RS11365	COG3386	PFAM SMP-30 Gluconolaconase
C6Y57_RS11380	COG3963	phosphatidate phosphatase activity
C6Y57_RS11435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C6Y57_RS11445	COG3135	benzoate transporter
C6Y57_RS11460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6Y57_RS11490	COG0285	dihydrofolate synthase activity
C6Y57_RS11500	COG1074	ATP-dependent DNA helicase activity
C6Y57_RS11505	COG2887	Belongs to the helicase family. UvrD subfamily
C6Y57_RS11510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C6Y57_RS11515	COG3178	'Phosphotransferase
C6Y57_RS11520	COG2205	protein histidine kinase activity
C6Y57_RS11540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6Y57_RS11545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6Y57_RS11545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6Y57_RS11560	COG2205	protein histidine kinase activity
C6Y57_RS11565	COG0745	RESPONSE REGULATOR receiver
C6Y57_RS11630	COG1396	sequence-specific DNA binding
C6Y57_RS11635	COG2840	Smr protein MutS2
C6Y57_RS11645	COG4395	Tim44
C6Y57_RS11665	COG0237	dephospho-CoA kinase activity
C6Y57_RS11695	COG1981	membrane
C6Y57_RS11700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6Y57_RS11705	COG1331	Highly conserved protein containing a thioredoxin domain
C6Y57_RS11740	COG1122	ATPase activity
C6Y57_RS11745	COG4120	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS11765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6Y57_RS11790	COG1024	Enoyl-CoA hydratase
C6Y57_RS11795	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS11835	COG1473	amidohydrolase
C6Y57_RS11840	COG1686	Belongs to the peptidase S11 family
C6Y57_RS11845	COG0523	cobalamin synthesis protein
C6Y57_RS11885	COG4536	flavin adenine dinucleotide binding
C6Y57_RS11930	COG2217	Heavy metal translocating P-type atpase
C6Y57_RS11935	COG0789	Transcriptional regulator
C6Y57_RS11950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6Y57_RS12005	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C6Y57_RS12025	COG2884	Cell division ATP-binding protein ftsE
C6Y57_RS12045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C6Y57_RS12075	COG0287	Prephenate dehydrogenase
C6Y57_RS12085	COG2226	methyltransferase
C6Y57_RS12120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6Y57_RS12135	COG0300	oxidoreductase activity
C6Y57_RS12150	COG0602	queuosine metabolic process
C6Y57_RS12155	COG0720	synthase
C6Y57_RS12165	COG2086	electron transfer activity
C6Y57_RS12170	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6Y57_RS12180	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6Y57_RS12210	COG0252	asparaginase activity
C6Y57_RS12215	COG1802	Transcriptional regulator
C6Y57_RS12225	COG1126	abc transporter atp-binding protein
C6Y57_RS12245	COG0765	amino acid transport
C6Y57_RS12250	COG0765	amino acid transport
C6Y57_RS12255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6Y57_RS12280	COG2194	sulfuric ester hydrolase activity
C6Y57_RS12310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6Y57_RS12325	COG0494	nUDIX hydrolase
C6Y57_RS12350	COG0552	protein localization to endoplasmic reticulum
C6Y57_RS12355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C6Y57_RS12375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6Y57_RS12395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6Y57_RS12405	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6Y57_RS12415	COG1280	lysine exporter protein (LysE YggA)
C6Y57_RS12475	COG1953	Uracil, thiamine, allantoin
C6Y57_RS12530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6Y57_RS12535	COG1946	Acyl-CoA thioesterase
C6Y57_RS12545	COG0004	ammonium transporteR
C6Y57_RS12555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6Y57_RS12560	COG0697	spore germination
C6Y57_RS12565	COG2264	protein methyltransferase activity
C6Y57_RS12620	COG2226	methyltransferase
C6Y57_RS12625	COG1040	competence protein
C6Y57_RS12655	COG0527	aspartate kinase activity
C6Y57_RS12670	COG2890	protein-(glutamine-N5) methyltransferase activity
C6Y57_RS12695	COG1376	ErfK ybiS ycfS ynhG family protein
C6Y57_RS12700	COG0739	heme binding
C6Y57_RS12765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6Y57_RS12830	COG0799	negative regulation of ribosome biogenesis
C6Y57_RS12850	COG0793	Belongs to the peptidase S41A family
C6Y57_RS12870	COG0583	DNA-binding transcription factor activity
C6Y57_RS12890	COG0288	reversible hydration of carbon dioxide
C6Y57_RS12905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6Y57_RS12910	COG1605	Chorismate mutase
C6Y57_RS12910	COG0287	Prephenate dehydrogenase
C6Y57_RS12920	COG1704	LemA family
C6Y57_RS12925	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C6Y57_RS12940	COG2270	Major facilitator Superfamily
C6Y57_RS12955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6Y57_RS12955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C6Y57_RS12975	COG5425	PFAM Usg family protein
C6Y57_RS12985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6Y57_RS13055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6Y57_RS13065	COG0559	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS13100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C6Y57_RS13105	COG0738	Major facilitator superfamily
C6Y57_RS13110	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS13120	COG0142	geranyltranstransferase activity
C6Y57_RS13140	COG0183	Belongs to the thiolase family
C6Y57_RS13165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C6Y57_RS13170	COG1329	Transcriptional regulator
C6Y57_RS13185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6Y57_RS13190	COG2258	MOSC domain
C6Y57_RS13230	COG0488	(ABC) transporter
C6Y57_RS13250	COG0469	pyruvate kinase activity
C6Y57_RS13255	COG0457	Tetratricopeptide repeat
C6Y57_RS13265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6Y57_RS13300	COG3321	synthase
C6Y57_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS13300	COG0604	alcohol dehydrogenase
C6Y57_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS13375	COG1692	metallophosphoesterase
C6Y57_RS13380	COG1253	flavin adenine dinucleotide binding
C6Y57_RS13410	COG1132	(ABC) transporter
C6Y57_RS13425	COG0483	inositol monophosphate 1-phosphatase activity
C6Y57_RS13480	COG0848	biopolymer transport protein
C6Y57_RS13500	COG2885	chlorophyll binding
C6Y57_RS13515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6Y57_RS13540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6Y57_RS13560	COG0477	Major facilitator Superfamily
C6Y57_RS13580	COG1522	sequence-specific DNA binding
C6Y57_RS13590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6Y57_RS13595	COG1136	(ABC) transporter
C6Y57_RS13595	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6Y57_RS13610	COG0848	biopolymer transport protein
C6Y57_RS13640	COG3920	Histidine kinase
C6Y57_RS13655	COG0784	Response regulator, receiver
C6Y57_RS13670	COG3920	Histidine kinase
C6Y57_RS13670	COG2202	Pas domain
C6Y57_RS13690	COG0564	pseudouridine synthase activity
C6Y57_RS13695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6Y57_RS13710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C6Y57_RS13735	COG1012	belongs to the aldehyde dehydrogenase family
C6Y57_RS13790	COG1129	ABC transporter
C6Y57_RS13795	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS13800	COG1879	ABC-type sugar transport system periplasmic component
C6Y57_RS13805	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS13810	COG2376	Dihydroxyacetone kinase
C6Y57_RS13815	COG1461	Dihydroxyacetone kinase
C6Y57_RS13820	COG2376	Dihydroxyacetone kinase
C6Y57_RS13825	COG1461	Dihydroxyacetone kinase
C6Y57_RS13840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6Y57_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS13880	COG2224	Isocitrate lyase
C6Y57_RS13900	COG3842	ATPase activity
C6Y57_RS13905	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6Y57_RS13910	COG1177	transmembrane transport
C6Y57_RS14040	COG0601	transmembrane transport
C6Y57_RS14045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6Y57_RS14050	COG0444	Belongs to the ABC transporter superfamily
C6Y57_RS14055	COG4608	Belongs to the ABC transporter superfamily
C6Y57_RS14060	COG4175	Glycine betaine
C6Y57_RS14060	COG3448	diguanylate cyclase activity
C6Y57_RS14065	COG4176	ABC-type proline glycine betaine transport system permease component
C6Y57_RS14095	COG1522	sequence-specific DNA binding
C6Y57_RS14105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6Y57_RS14105	COG0512	Glutamine amidotransferase of anthranilate synthase
C6Y57_RS14110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C6Y57_RS14125	COG1051	belongs to the nudix hydrolase family
C6Y57_RS14130	COG3047	cAMP biosynthetic process
C6Y57_RS14135	COG0435	Glutathione S-transferase
C6Y57_RS14160	COG0714	Associated with various cellular activities
C6Y57_RS14175	COG0617	tRNA 3'-terminal CCA addition
C6Y57_RS14190	COG3153	acetyltransferase
C6Y57_RS14210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6Y57_RS14215	COG1132	(ABC) transporter
C6Y57_RS14220	COG1132	(ABC) transporter
C6Y57_RS14235	COG2857	Cytochrome c1
C6Y57_RS14235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C6Y57_RS14250	COG2030	dehydratase
C6Y57_RS14255	COG0012	GTP binding
C6Y57_RS14280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6Y57_RS14300	COG1496	oxidoreductase activity
C6Y57_RS14335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6Y57_RS14345	COG2205	protein histidine kinase activity
C6Y57_RS14350	COG0745	RESPONSE REGULATOR receiver
C6Y57_RS14355	COG1846	Transcriptional regulator
C6Y57_RS14375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6Y57_RS14385	COG1278	Cold shock
C6Y57_RS14390	COG0739	heme binding
C6Y57_RS14390	COG1196	nuclear chromosome segregation
C6Y57_RS14390	COG0741	lytic transglycosylase activity
C6Y57_RS14395	COG0556	nucleotide-excision repair
C6Y57_RS14450	COG1522	sequence-specific DNA binding
C6Y57_RS14455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6Y57_RS14460	COG0492	ferredoxin-NADP+ reductase activity
C6Y57_RS14465	COG0583	DNA-binding transcription factor activity
C6Y57_RS14480	COG0436	Aminotransferase
C6Y57_RS14485	COG0625	glutathione transferase activity
C6Y57_RS14490	COG1278	Cold shock
C6Y57_RS14500	COG1136	(ABC) transporter
C6Y57_RS14525	COG2321	neutral zinc metallopeptidase
C6Y57_RS14545	COG0358	DNA primase activity
C6Y57_RS14555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6Y57_RS14575	COG2968	Membrane
C6Y57_RS14615	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C6Y57_RS14640	COG1335	isochorismatase
C6Y57_RS14645	COG2824	Alkylphosphonate utilization operon protein PhnA
C6Y57_RS14650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6Y57_RS14675	COG2267	carboxylic ester hydrolase activity
C6Y57_RS14700	COG0477	Major facilitator Superfamily
C6Y57_RS14710	COG0640	Transcriptional regulator
C6Y57_RS14740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6Y57_RS14745	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6Y57_RS14760	COG1914	H( )-stimulated, divalent metal cation uptake system
C6Y57_RS14830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6Y57_RS14835	COG0849	cell division
C6Y57_RS14840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6Y57_RS14855	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6Y57_RS14875	COG0006	proline dipeptidase activity
C6Y57_RS14885	COG1999	signal sequence binding
C6Y57_RS14900	COG0210	DNA helicase
C6Y57_RS14915	COG0277	FAD linked oxidase domain protein
C6Y57_RS14945	COG2814	Major facilitator Superfamily
C6Y57_RS14980	COG0330	HflC and HflK could
C6Y57_RS14995	COG2081	HI0933 family
C6Y57_RS15000	COG0560	Phosphoserine phosphatase
C6Y57_RS15015	COG0028	Belongs to the TPP enzyme family
C6Y57_RS15020	COG0440	acetolactate synthase activity
C6Y57_RS15025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6Y57_RS15060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6Y57_RS15085	COG0384	phenazine biosynthesis protein PhzF
C6Y57_RS15125	COG0310	cobalt ion transport
C6Y57_RS15135	COG4413	Urea transporter
C6Y57_RS15175	COG1649	PFAM Uncharacterised BCR, COG1649
C6Y57_RS15190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6Y57_RS15195	COG0842	Transport permease protein
C6Y57_RS15195	COG1129	ABC transporter
C6Y57_RS15200	COG0842	Transport permease protein
C6Y57_RS15215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6Y57_RS15220	COG1120	ATPase activity
C6Y57_RS15235	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6Y57_RS15245	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS15250	COG4154	Belongs to the RbsD FucU family
C6Y57_RS15270	COG0586	Pfam SNARE associated Golgi protein
C6Y57_RS15275	COG1253	flavin adenine dinucleotide binding
C6Y57_RS15285	COG4150	thiosulfate binding
C6Y57_RS15290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6Y57_RS15295	COG4208	sulfate ABC transporter
C6Y57_RS15310	COG4651	solute:proton antiporter activity
C6Y57_RS15310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6Y57_RS15465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6Y57_RS15520	COG0024	Methionine aminopeptidase
C6Y57_RS15555	COG0436	Aminotransferase
C6Y57_RS15565	COG1494	fructose-1,6-bisphosphatase
C6Y57_RS15585	COG0346	lactoylglutathione lyase activity
C6Y57_RS15645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6Y57_RS15675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6Y57_RS15765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C6Y57_RS15830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C6Y57_RS15880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6Y57_RS15885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6Y57_RS15895	COG2885	chlorophyll binding
C6Y57_RS15910	COG1785	Belongs to the alkaline phosphatase family
C6Y57_RS15915	COG0538	isocitrate dehydrogenase activity
C6Y57_RS15925	COG0693	protein deglycase activity
C6Y57_RS15930	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6Y57_RS15940	COG2358	TRAP transporter, solute receptor (TAXI family
C6Y57_RS15955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6Y57_RS15955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C6Y57_RS15960	COG4770	biotin carboxylase activity
C6Y57_RS15965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6Y57_RS15970	COG3800	Transcriptional regulator
C6Y57_RS15970	COG1396	sequence-specific DNA binding
C6Y57_RS16020	COG1760	l-serine dehydratase
C6Y57_RS16035	COG1686	Belongs to the peptidase S11 family
C6Y57_RS16055	COG0537	adenosine 5'-monophosphoramidase activity
C6Y57_RS16065	COG0584	glycerophosphoryl diester phosphodiesterase
C6Y57_RS16120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6Y57_RS16145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C6Y57_RS16150	COG0372	Belongs to the citrate synthase family
C6Y57_RS16170	COG0303	'Molybdopterin
C6Y57_RS16190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6Y57_RS16235	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C6Y57_RS16240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6Y57_RS16245	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6Y57_RS16245	COG0022	dehydrogenase e1 component
C6Y57_RS16250	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6Y57_RS16255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6Y57_RS16270	COG2867	negative regulation of translational initiation
C6Y57_RS16275	COG1028	Short-chain dehydrogenase reductase Sdr
C6Y57_RS16280	COG1546	Belongs to the CinA family
C6Y57_RS16280	COG1058	Belongs to the CinA family
C6Y57_RS16295	COG3852	Histidine kinase
C6Y57_RS16300	COG2204	response regulator
C6Y57_RS16305	COG5000	phosphorelay sensor kinase activity
C6Y57_RS16310	COG2204	response regulator
C6Y57_RS16315	COG0569	domain protein
C6Y57_RS16335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6Y57_RS16385	COG2188	Transcriptional regulator
C6Y57_RS16395	COG2095	MarC family integral membrane protein
C6Y57_RS16400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6Y57_RS16435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6Y57_RS16440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6Y57_RS16445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6Y57_RS16450	COG0583	DNA-binding transcription factor activity
C6Y57_RS16455	COG1960	acyl-CoA dehydrogenase activity
C6Y57_RS16460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C6Y57_RS16485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6Y57_RS16535	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6Y57_RS16560	COG1686	Belongs to the peptidase S11 family
C6Y57_RS16580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6Y57_RS16585	COG3956	TIGRFAM MazG family protein
C6Y57_RS16595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family