locus-tag	class	description
MR74_RS00015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MR74_RS00020	COG1331	Highly conserved protein containing a thioredoxin domain
MR74_RS00025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MR74_RS00065	COG4120	Belongs to the binding-protein-dependent transport system permease family
MR74_RS00085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MR74_RS00110	COG1024	Enoyl-CoA hydratase
MR74_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
MR74_RS00125	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS00145	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS00155	COG1473	amidohydrolase
MR74_RS00160	COG1686	Belongs to the peptidase S11 family
MR74_RS00205	COG4536	flavin adenine dinucleotide binding
MR74_RS00255	COG0789	Transcriptional regulator
MR74_RS00270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MR74_RS00310	COG0745	RESPONSE REGULATOR receiver
MR74_RS00325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MR74_RS00345	COG2884	Cell division ATP-binding protein ftsE
MR74_RS00365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MR74_RS00395	COG0287	Prephenate dehydrogenase
MR74_RS00405	COG2226	methyltransferase
MR74_RS00440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MR74_RS00470	COG0602	queuosine metabolic process
MR74_RS00475	COG0720	synthase
MR74_RS00485	COG2086	electron transfer activity
MR74_RS00490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MR74_RS00500	COG1250	3-hydroxyacyl-CoA dehydrogenase
MR74_RS00530	COG1802	Transcriptional regulator
MR74_RS00540	COG1126	abc transporter atp-binding protein
MR74_RS00560	COG0765	amino acid transport
MR74_RS00565	COG0765	amino acid transport
MR74_RS00570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MR74_RS00595	COG2194	sulfuric ester hydrolase activity
MR74_RS00635	COG0494	nUDIX hydrolase
MR74_RS00660	COG0552	protein localization to endoplasmic reticulum
MR74_RS00665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MR74_RS00685	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MR74_RS00705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MR74_RS00715	COG0508	dehydrogenase complex catalyzes the overall conversion of
MR74_RS00725	COG1280	lysine exporter protein (LysE YggA)
MR74_RS00840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MR74_RS00845	COG1946	Acyl-CoA thioesterase
MR74_RS00855	COG0004	ammonium transporteR
MR74_RS00865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MR74_RS00870	COG0697	spore germination
MR74_RS00875	COG2264	protein methyltransferase activity
MR74_RS00930	COG2226	methyltransferase
MR74_RS00935	COG1040	competence protein
MR74_RS00965	COG0527	aspartate kinase activity
MR74_RS00980	COG2890	protein-(glutamine-N5) methyltransferase activity
MR74_RS01015	COG0739	heme binding
MR74_RS01125	COG0799	negative regulation of ribosome biogenesis
MR74_RS01145	COG0793	Belongs to the peptidase S41A family
MR74_RS01165	COG0583	DNA-binding transcription factor activity
MR74_RS01185	COG0288	reversible hydration of carbon dioxide
MR74_RS01205	COG1605	Chorismate mutase
MR74_RS01205	COG0287	Prephenate dehydrogenase
MR74_RS01215	COG1704	LemA family
MR74_RS01220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MR74_RS01235	COG2270	Major facilitator Superfamily
MR74_RS01250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MR74_RS01250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MR74_RS01270	COG5425	PFAM Usg family protein
MR74_RS01280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MR74_RS01400	COG0738	Major facilitator superfamily
MR74_RS01415	COG0142	geranyltranstransferase activity
MR74_RS01465	COG1329	Transcriptional regulator
MR74_RS01480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MR74_RS01535	COG3750	Belongs to the UPF0335 family
MR74_RS01565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MR74_RS01570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MR74_RS01600	COG0604	alcohol dehydrogenase
MR74_RS01600	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS01600	COG3321	synthase
MR74_RS01675	COG1692	metallophosphoesterase
MR74_RS01680	COG1253	flavin adenine dinucleotide binding
MR74_RS01710	COG1132	(ABC) transporter
MR74_RS01770	COG0824	Thioesterase
MR74_RS01780	COG0848	biopolymer transport protein
MR74_RS01800	COG2885	chlorophyll binding
MR74_RS01815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MR74_RS01830	COG0385	Bile acid
MR74_RS01840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MR74_RS01860	COG0477	Major facilitator Superfamily
MR74_RS01880	COG1522	sequence-specific DNA binding
MR74_RS01890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MR74_RS01895	COG1136	(ABC) transporter
MR74_RS01895	COG4591	ABC-type transport system involved in lipoprotein release permease component
MR74_RS01910	COG0848	biopolymer transport protein
MR74_RS01940	COG3920	Histidine kinase
MR74_RS01955	COG0784	Response regulator, receiver
MR74_RS01990	COG0564	pseudouridine synthase activity
MR74_RS01995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MR74_RS02010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MR74_RS02035	COG1012	belongs to the aldehyde dehydrogenase family
MR74_RS02100	COG1879	ABC-type sugar transport system periplasmic component
MR74_RS02105	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS02110	COG2376	Dihydroxyacetone kinase
MR74_RS02115	COG1461	Dihydroxyacetone kinase
MR74_RS02130	COG1461	Dihydroxyacetone kinase
MR74_RS02145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MR74_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS02180	COG2224	Isocitrate lyase
MR74_RS02200	COG3842	ATPase activity
MR74_RS02330	COG0747	negative chemotaxis
MR74_RS02335	COG0747	negative chemotaxis
MR74_RS02340	COG0747	negative chemotaxis
MR74_RS02345	COG0601	transmembrane transport
MR74_RS02350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MR74_RS02355	COG0444	Belongs to the ABC transporter superfamily
MR74_RS02360	COG4608	Belongs to the ABC transporter superfamily
MR74_RS02370	COG4176	ABC-type proline glycine betaine transport system permease component
MR74_RS02400	COG1522	sequence-specific DNA binding
MR74_RS02410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MR74_RS02410	COG0512	Glutamine amidotransferase of anthranilate synthase
MR74_RS02430	COG1051	belongs to the nudix hydrolase family
MR74_RS02435	COG3047	cAMP biosynthetic process
MR74_RS02440	COG0435	Glutathione S-transferase
MR74_RS02465	COG0714	Associated with various cellular activities
MR74_RS02480	COG0617	tRNA 3'-terminal CCA addition
MR74_RS02555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MR74_RS02555	COG2857	Cytochrome c1
MR74_RS02570	COG2030	dehydratase
MR74_RS02595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MR74_RS02650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MR74_RS02655	COG2205	protein histidine kinase activity
MR74_RS02660	COG0745	RESPONSE REGULATOR receiver
MR74_RS02665	COG1846	Transcriptional regulator
MR74_RS02685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MR74_RS02695	COG1278	Cold shock
MR74_RS02700	COG0741	lytic transglycosylase activity
MR74_RS02700	COG1196	nuclear chromosome segregation
MR74_RS02700	COG0739	heme binding
MR74_RS02705	COG0556	nucleotide-excision repair
MR74_RS02755	COG1522	sequence-specific DNA binding
MR74_RS02760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MR74_RS02765	COG0492	ferredoxin-NADP+ reductase activity
MR74_RS02785	COG0436	Aminotransferase
MR74_RS02790	COG0625	glutathione transferase activity
MR74_RS02795	COG1278	Cold shock
MR74_RS02830	COG2321	neutral zinc metallopeptidase
MR74_RS02885	COG2968	Membrane
MR74_RS02955	COG1335	isochorismatase
MR74_RS02960	COG2824	Alkylphosphonate utilization operon protein PhnA
MR74_RS02965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MR74_RS02990	COG2267	carboxylic ester hydrolase activity
MR74_RS03015	COG0477	Major facilitator Superfamily
MR74_RS03025	COG0640	Transcriptional regulator
MR74_RS03055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MR74_RS03075	COG1914	H( )-stimulated, divalent metal cation uptake system
MR74_RS03135	COG1181	Belongs to the D-alanine--D-alanine ligase family
MR74_RS03140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MR74_RS03145	COG0849	cell division
MR74_RS03150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MR74_RS03165	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MR74_RS03195	COG1999	signal sequence binding
MR74_RS03210	COG0210	DNA helicase
MR74_RS03225	COG0277	FAD linked oxidase domain protein
MR74_RS03305	COG2081	HI0933 family
MR74_RS03310	COG0560	Phosphoserine phosphatase
MR74_RS03335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MR74_RS03350	COG3158	transport of potassium into the cell
MR74_RS03370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MR74_RS03395	COG0384	phenazine biosynthesis protein PhzF
MR74_RS03440	COG0310	cobalt ion transport
MR74_RS03450	COG4413	Urea transporter
MR74_RS03505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MR74_RS03515	COG0842	Transport permease protein
MR74_RS03530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MR74_RS03535	COG1120	ATPase activity
MR74_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS03565	COG4154	Belongs to the RbsD FucU family
MR74_RS03585	COG0586	Pfam SNARE associated Golgi protein
MR74_RS03590	COG1253	flavin adenine dinucleotide binding
MR74_RS03605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MR74_RS03610	COG4208	sulfate ABC transporter
MR74_RS03625	COG4651	solute:proton antiporter activity
MR74_RS03625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MR74_RS03655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MR74_RS03675	COG0583	DNA-binding transcription factor activity
MR74_RS03805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MR74_RS03860	COG0024	Methionine aminopeptidase
MR74_RS03980	COG0517	IMP dehydrogenase activity
MR74_RS03980	COG0516	GMP reductase activity
MR74_RS03985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MR74_RS04015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MR74_RS04105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MR74_RS04170	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MR74_RS04220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MR74_RS04225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MR74_RS04250	COG1785	Belongs to the alkaline phosphatase family
MR74_RS04255	COG0538	isocitrate dehydrogenase activity
MR74_RS04265	COG0693	protein deglycase activity
MR74_RS04270	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MR74_RS04300	COG4770	biotin carboxylase activity
MR74_RS04305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MR74_RS04310	COG3800	Transcriptional regulator
MR74_RS04310	COG1396	sequence-specific DNA binding
MR74_RS04355	COG1760	l-serine dehydratase
MR74_RS04400	COG0584	glycerophosphoryl diester phosphodiesterase
MR74_RS04480	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MR74_RS04485	COG0372	Belongs to the citrate synthase family
MR74_RS04505	COG0303	'Molybdopterin
MR74_RS04525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MR74_RS04570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MR74_RS04575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MR74_RS04580	COG0022	dehydrogenase e1 component
MR74_RS04580	COG0508	dehydrogenase complex catalyzes the overall conversion of
MR74_RS04605	COG2867	negative regulation of translational initiation
MR74_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS04630	COG3852	Histidine kinase
MR74_RS04765	COG0343	queuine tRNA-ribosyltransferase activity
MR74_RS04775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MR74_RS04785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MR74_RS04790	COG0583	DNA-binding transcription factor activity
MR74_RS04795	COG1960	acyl-CoA dehydrogenase activity
MR74_RS04800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MR74_RS04810	COG3617	BRO family, N-terminal domain
MR74_RS04880	COG1752	Esterase of the alpha-beta hydrolase superfamily
MR74_RS04930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MR74_RS04960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MR74_RS04965	COG0006	proline dipeptidase activity
MR74_RS04975	COG1566	PFAM secretion protein HlyD family protein
MR74_RS04980	COG2814	Major facilitator Superfamily
MR74_RS04985	COG0427	acetyl-CoA hydrolase
MR74_RS04995	COG3706	GGDEF domain
MR74_RS05010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MR74_RS05030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MR74_RS05095	COG0668	transmembrane transport
MR74_RS05150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MR74_RS05160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MR74_RS05175	COG0633	Ferredoxin
MR74_RS05205	COG1127	ABC transporter
MR74_RS05215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MR74_RS05220	COG4948	Mandelate Racemase Muconate Lactonizing
MR74_RS05230	COG0280	phosphate acetyltransferase
MR74_RS05230	COG0281	malic enzyme
MR74_RS05250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MR74_RS05255	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MR74_RS05275	COG0546	phosphoglycolate phosphatase activity
MR74_RS05285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MR74_RS05285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MR74_RS05290	COG0347	Belongs to the P(II) protein family
MR74_RS05330	COG0084	hydrolase, TatD family'
MR74_RS05360	COG1393	Belongs to the ArsC family
MR74_RS05500	COG2989	Protein conserved in bacteria
MR74_RS05550	COG2084	Dehydrogenase
MR74_RS05585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MR74_RS05610	COG0513	Belongs to the DEAD box helicase family
MR74_RS05630	COG2151	metal-sulfur cluster biosynthetic enzyme
MR74_RS05635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MR74_RS05640	COG0719	Fe-S assembly protein
MR74_RS05650	COG0719	Fe-S assembly protein
MR74_RS05660	COG2945	thiolester hydrolase activity
MR74_RS05685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MR74_RS05690	COG2833	Protein of unknown function (DUF455)
MR74_RS05705	COG3293	Transposase
MR74_RS05740	COG1530	ribonuclease E activity
MR74_RS05745	COG0436	Aminotransferase
MR74_RS05765	COG0511	ligase activity, forming carbon-carbon bonds
MR74_RS05770	COG0439	Biotin carboxylase
MR74_RS05780	COG4765	Protein conserved in bacteria
MR74_RS05850	COG1862	Preprotein translocase
MR74_RS05870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MR74_RS05885	COG0805	protein transport
MR74_RS05890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MR74_RS05900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MR74_RS05905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MR74_RS05910	COG1472	Belongs to the glycosyl hydrolase 3 family
MR74_RS05930	COG0316	Belongs to the HesB IscA family
MR74_RS05960	COG1573	uracil-dna glycosylase
MR74_RS05965	COG1522	sequence-specific DNA binding
MR74_RS05990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MR74_RS05995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MR74_RS06000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MR74_RS06010	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MR74_RS06015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MR74_RS06035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MR74_RS06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MR74_RS06045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MR74_RS06065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MR74_RS06145	COG0483	inositol monophosphate 1-phosphatase activity
MR74_RS06200	COG0346	lactoylglutathione lyase activity
MR74_RS06215	COG1007	ATP synthesis coupled electron transport
MR74_RS06255	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MR74_RS06260	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MR74_RS06280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MR74_RS06360	COG0010	Belongs to the arginase family
MR74_RS06450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MR74_RS06490	COG2989	Protein conserved in bacteria
MR74_RS06510	COG0113	porphobilinogen synthase activity
MR74_RS06545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MR74_RS06570	COG1126	abc transporter atp-binding protein
MR74_RS06580	COG4597	amino acid ABC transporter
MR74_RS06590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MR74_RS06605	COG0626	cystathionine gamma-synthase activity
MR74_RS06720	COG1620	l-lactate permease
MR74_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS06765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MR74_RS06780	COG0243	molybdopterin cofactor binding
MR74_RS06790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MR74_RS06825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MR74_RS06830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MR74_RS06835	COG0314	molybdopterin synthase activity
MR74_RS06905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MR74_RS06910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MR74_RS06920	COG0739	heme binding
MR74_RS06970	COG0494	nUDIX hydrolase
MR74_RS06990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MR74_RS07025	COG0681	Belongs to the peptidase S26 family
MR74_RS07040	COG2207	Transcriptional regulator
MR74_RS07045	COG2223	nitrite transmembrane transporter activity
MR74_RS07100	COG3743	rRNA binding
MR74_RS07100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MR74_RS07135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MR74_RS07170	COG0625	glutathione transferase activity
MR74_RS07190	COG1573	uracil-dna glycosylase
MR74_RS07205	COG0308	aminopeptidase N
MR74_RS07210	COG2205	protein histidine kinase activity
MR74_RS07210	COG2202	Pas domain
MR74_RS07220	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MR74_RS07240	COG3088	subunit of a heme lyase
MR74_RS07245	COG1138	Cytochrome C-type biogenesis protein
MR74_RS07255	COG4235	cytochrome complex assembly
MR74_RS07270	COG0745	RESPONSE REGULATOR receiver
MR74_RS07340	COG4695	Portal protein
MR74_RS07395	COG2205	protein histidine kinase activity
MR74_RS07405	COG2166	iron-sulfur cluster assembly
MR74_RS07430	COG4957	zinc ion binding
MR74_RS07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MR74_RS07470	COG0433	COG0433 Predicted ATPase
MR74_RS07485	COG2186	Transcriptional regulator
MR74_RS07495	COG2336	PFAM SpoVT AbrB
MR74_RS07505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MR74_RS07555	COG0673	inositol 2-dehydrogenase activity
MR74_RS07565	COG1879	ABC-type sugar transport system periplasmic component
MR74_RS07570	COG1172	Belongs to the binding-protein-dependent transport system permease family
MR74_RS07590	COG0438	transferase activity, transferring glycosyl groups
MR74_RS07590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MR74_RS07600	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MR74_RS07600	COG0662	Cupin 2, conserved barrel domain protein
MR74_RS07625	COG2801	Transposase and inactivated derivatives
MR74_RS07630	COG2801	Transposase and inactivated derivatives
MR74_RS07665	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MR74_RS07725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MR74_RS07740	COG2351	hydroxyisourate hydrolase activity
MR74_RS07750	COG1268	BioY protein
MR74_RS07815	COG1194	a g-specific adenine glycosylase
MR74_RS07835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MR74_RS07845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MR74_RS07865	COG0612	Peptidase, M16
MR74_RS07870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MR74_RS07890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MR74_RS07890	COG0678	peroxiredoxin activity
MR74_RS07945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MR74_RS07955	COG0312	modulator of DNA gyrase
MR74_RS07975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MR74_RS07985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MR74_RS08010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MR74_RS08040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MR74_RS08045	COG0305	Participates in initiation and elongation during chromosome replication
MR74_RS08065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MR74_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS08075	COG1183	phosphatidylcholine synthase activity
MR74_RS08120	COG1741	Belongs to the pirin family
MR74_RS08130	COG2261	transglycosylase associated protein
MR74_RS08140	COG1722	exodeoxyribonuclease VII activity
MR74_RS08145	COG0123	including yeast histone deacetylase and acetoin utilization protein
MR74_RS08150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MR74_RS08150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MR74_RS08175	COG1278	Cold shock
MR74_RS08190	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MR74_RS08195	COG0484	heat shock protein binding
MR74_RS08210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MR74_RS08225	COG1960	acyl-CoA dehydrogenase activity
MR74_RS08260	COG0009	L-threonylcarbamoyladenylate synthase
MR74_RS08270	COG0751	glycine-tRNA ligase activity
MR74_RS08285	COG0142	geranyltranstransferase activity
MR74_RS08380	COG3773	Cell wall hydrolase
MR74_RS08405	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MR74_RS08410	COG0477	Major facilitator Superfamily
MR74_RS08420	COG1393	Belongs to the ArsC family
MR74_RS08435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MR74_RS08435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MR74_RS08500	COG0402	S-adenosylhomocysteine deaminase activity
MR74_RS08520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MR74_RS08525	COG2080	2 iron, 2 sulfur cluster binding
MR74_RS08540	COG3257	ureidoglycine aminohydrolase activity
MR74_RS08545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MR74_RS08595	COG0019	diaminopimelate decarboxylase activity
MR74_RS08635	COG1346	cytolysis
MR74_RS08640	COG1380	Effector of murein hydrolase LrgA
MR74_RS08710	COG0534	Mate efflux family protein
MR74_RS08730	COG0717	Belongs to the dCTP deaminase family
MR74_RS08745	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MR74_RS08755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MR74_RS08775	COG2326	polyphosphate kinase activity
MR74_RS08820	COG0318	PFAM AMP-dependent synthetase and ligase
MR74_RS08855	COG0493	'glutamate synthase
MR74_RS08870	COG1309	transcriptional regulator
MR74_RS08890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MR74_RS08900	COG4191	Histidine kinase
MR74_RS08980	COG3617	BRO family, N-terminal domain
MR74_RS08990	COG3617	BRO family, N-terminal domain
MR74_RS09030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MR74_RS09045	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MR74_RS09190	COG0582	viral genome integration into host DNA
MR74_RS09225	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS09235	COG3254	rhamnose metabolic process
MR74_RS09245	COG3842	ATPase activity
MR74_RS09250	COG0395	ABC-type sugar transport system, permease component
MR74_RS09255	COG1175	transmembrane transport
MR74_RS09295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MR74_RS09310	COG1174	glycine betaine transport
MR74_RS09315	COG1125	glycine betaine transport
MR74_RS09320	COG1174	glycine betaine transport
MR74_RS09340	COG0351	phosphomethylpyrimidine kinase
MR74_RS09365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MR74_RS09370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MR74_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
MR74_RS09435	COG2197	response regulator
MR74_RS09450	COG1218	3'(2'),5'-bisphosphate nucleotidase
MR74_RS09470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MR74_RS09475	COG2197	response regulator
MR74_RS09500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MR74_RS09520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MR74_RS09530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MR74_RS09530	COG1648	precorrin-2 dehydrogenase activity
MR74_RS09540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MR74_RS09545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MR74_RS09550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MR74_RS09590	COG2860	membrane
MR74_RS09595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MR74_RS09625	COG0071	Belongs to the small heat shock protein (HSP20) family
MR74_RS09635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MR74_RS09640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MR74_RS09655	COG1137	ATPase activity
MR74_RS09660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MR74_RS09670	COG0616	signal peptide processing
MR74_RS09685	COG0116	Belongs to the methyltransferase superfamily
MR74_RS09685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MR74_RS09705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MR74_RS09710	COG0281	malic enzyme
MR74_RS09710	COG0280	phosphate acetyltransferase
MR74_RS09715	COG0281	malic enzyme
MR74_RS09715	COG0280	phosphate acetyltransferase
MR74_RS09730	COG0180	Tryptophanyl-tRNA synthetase
MR74_RS09740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MR74_RS09745	COG1376	ErfK ybiS ycfS ynhG family protein
MR74_RS09745	COG1388	LysM domain
MR74_RS09755	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MR74_RS09795	COG2153	protein acetylation
MR74_RS09805	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MR74_RS09830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MR74_RS09835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MR74_RS09850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MR74_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS09865	COG2226	methyltransferase
MR74_RS09870	COG0384	phenazine biosynthesis protein PhzF
MR74_RS09885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MR74_RS09890	COG4208	sulfate ABC transporter
MR74_RS09900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MR74_RS09955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MR74_RS09960	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MR74_RS09975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MR74_RS09995	COG0670	Belongs to the BI1 family
MR74_RS10005	COG4181	ATPase activity
MR74_RS10020	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MR74_RS10040	COG3339	Conserved Protein
MR74_RS10110	COG1272	protein, Hemolysin III
MR74_RS10140	COG1072	(Pantothenic acid kinase))
MR74_RS10145	COG1073	alpha beta
MR74_RS10165	COG0489	protein tyrosine kinase activity
MR74_RS10205	COG1376	ErfK ybiS ycfS ynhG family protein
MR74_RS10230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MR74_RS10235	COG1845	cytochrome c oxidase, subunit III
MR74_RS10240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MR74_RS10255	COG3474	cytochrome
MR74_RS10265	COG1605	Chorismate mutase
MR74_RS10265	COG0077	Prephenate dehydratase
MR74_RS10285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MR74_RS10310	COG0583	DNA-binding transcription factor activity
MR74_RS10315	COG2855	membrane
MR74_RS10320	COG0539	negative regulation of cytoplasmic translation
MR74_RS10360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MR74_RS10365	COG1960	acyl-CoA dehydrogenase activity
MR74_RS10380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MR74_RS10425	COG4174	ABC transporter (Permease)
MR74_RS10430	COG4239	(ABC) transporter, permease
MR74_RS10435	COG4172	Belongs to the ABC transporter superfamily
MR74_RS10440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MR74_RS10475	COG1024	Enoyl-CoA hydratase
MR74_RS10500	COG0791	NLP P60 protein
MR74_RS10540	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MR74_RS10590	COG0195	Participates in both transcription termination and antitermination
MR74_RS10590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MR74_RS10600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MR74_RS10605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MR74_RS10645	COG0456	acetyltransferase
MR74_RS10655	COG0783	Belongs to the Dps family
MR74_RS10670	COG3773	Cell wall hydrolase
MR74_RS10680	COG0704	Plays a role in the regulation of phosphate uptake
MR74_RS10685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MR74_RS10700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MR74_RS10705	COG2832	Protein of unknown function (DUF454)
MR74_RS10715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MR74_RS10725	COG0606	chelatase, subunit chli
MR74_RS10735	COG3386	PFAM SMP-30 Gluconolaconase
MR74_RS10805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MR74_RS10830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MR74_RS10860	COG0285	dihydrofolate synthase activity
MR74_RS10880	COG2887	Belongs to the helicase family. UvrD subfamily
MR74_RS10895	COG2205	protein histidine kinase activity
MR74_RS10920	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MR74_RS10920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MR74_RS10935	COG2205	protein histidine kinase activity
MR74_RS10940	COG0745	RESPONSE REGULATOR receiver
MR74_RS11005	COG1396	sequence-specific DNA binding
MR74_RS11010	COG2840	Smr protein MutS2
MR74_RS11020	COG4395	Tim44
MR74_RS11040	COG0237	dephospho-CoA kinase activity
MR74_RS11085	COG4149	molybdate abc transporter
MR74_RS11090	COG0725	ABC transporter, periplasmic molybdate-binding protein
MR74_RS11110	COG0800	Aldolase
MR74_RS11130	COG2204	response regulator
MR74_RS11150	COG5310	Homospermidine synthase
MR74_RS11165	COG0330	HflC and HflK could
MR74_RS11185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MR74_RS11190	COG2951	lytic endotransglycosylase activity
MR74_RS11290	COG0071	Belongs to the small heat shock protein (HSP20) family
MR74_RS11320	COG0483	inositol monophosphate 1-phosphatase activity
MR74_RS11340	COG4566	intracellular signal transduction
MR74_RS11345	COG4191	Histidine kinase
MR74_RS11385	COG0508	dehydrogenase complex catalyzes the overall conversion of
MR74_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS11435	COG2186	Transcriptional regulator
MR74_RS11440	COG4944	Protein of unknown function (DUF1109)
MR74_RS11460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MR74_RS11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MR74_RS11465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MR74_RS11470	COG1169	isochorismate synthase
MR74_RS11480	COG1535	isochorismatase
MR74_RS11480	COG3433	isochorismatase activity
MR74_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS11500	COG1744	ABC transporter substrate-binding protein PnrA-like
MR74_RS11525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MR74_RS11535	COG1414	Transcriptional regulator
MR74_RS11545	COG1192	Involved in chromosome partitioning
MR74_RS11640	COG3842	ATPase activity
MR74_RS11645	COG1175	transmembrane transport
MR74_RS11660	COG2188	Transcriptional regulator
MR74_RS11680	COG1129	ABC transporter
MR74_RS11695	COG1228	amidohydrolase
MR74_RS11700	COG1012	belongs to the aldehyde dehydrogenase family
MR74_RS11715	COG5441	Belongs to the UPF0261 family
MR74_RS11730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MR74_RS11735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MR74_RS11765	COG3971	2-oxopent-4-enoate hydratase activity
MR74_RS11800	COG4213	ABC transporter substrate-binding protein
MR74_RS11815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MR74_RS11820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MR74_RS11835	COG1360	Flagellar Motor Protein
MR74_RS11885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MR74_RS11895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MR74_RS11900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MR74_RS11935	COG0735	belongs to the Fur family
MR74_RS11940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MR74_RS11955	COG0523	cobalamin synthesis protein
MR74_RS11960	COG1959	2 iron, 2 sulfur cluster binding
MR74_RS11965	COG2971	BadF BadG BcrA BcrD
MR74_RS12025	COG2337	Toxic component of a toxin-antitoxin (TA) module
MR74_RS12040	COG0235	Class ii aldolase
MR74_RS12060	COG0154	amidase activity
MR74_RS12075	COG0444	Belongs to the ABC transporter superfamily
MR74_RS12090	COG0747	negative chemotaxis
MR74_RS12135	COG1960	acyl-CoA dehydrogenase activity
MR74_RS12145	COG1250	3-hydroxyacyl-CoA dehydrogenase
MR74_RS12170	COG0601	transmembrane transport
MR74_RS12180	COG0444	Belongs to the ABC transporter superfamily
MR74_RS12185	COG4608	Belongs to the ABC transporter superfamily
MR74_RS12245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MR74_RS12250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MR74_RS12265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MR74_RS12290	COG0778	Nitroreductase
MR74_RS12300	COG1228	amidohydrolase
MR74_RS12320	COG1132	(ABC) transporter
MR74_RS12345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MR74_RS12380	COG2827	Endonuclease containing a URI domain
MR74_RS12445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MR74_RS12470	COG0251	oxidation-reduction process
MR74_RS12500	COG1802	Transcriptional regulator
MR74_RS12540	COG4608	Belongs to the ABC transporter superfamily
MR74_RS12545	COG0154	amidase activity
MR74_RS12600	COG1879	ABC-type sugar transport system periplasmic component
MR74_RS12605	COG1129	ABC transporter
MR74_RS12610	COG1129	ABC transporter
MR74_RS12625	COG0251	oxidation-reduction process
MR74_RS12635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MR74_RS12670	COG1609	Transcriptional regulator
MR74_RS12675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MR74_RS12680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MR74_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS12695	COG5001	Diguanylate cyclase
MR74_RS12775	COG2011	ABC-type metal ion transport system permease component
MR74_RS12855	COG2186	Transcriptional regulator
MR74_RS12875	COG0129	dihydroxy-acid dehydratase activity
MR74_RS12880	COG3734	2-keto-3-deoxy-galactonokinase
MR74_RS12885	COG0800	Aldolase
MR74_RS12890	COG4213	ABC transporter substrate-binding protein
MR74_RS12895	COG1129	ABC transporter
MR74_RS12935	COG0402	S-adenosylhomocysteine deaminase activity
MR74_RS12965	COG1522	sequence-specific DNA binding
MR74_RS12980	COG0243	molybdopterin cofactor binding
MR74_RS13000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MR74_RS13020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MR74_RS13035	COG1012	belongs to the aldehyde dehydrogenase family
MR74_RS13055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MR74_RS13060	COG2183	response to ionizing radiation
MR74_RS13065	COG0640	Transcriptional regulator
MR74_RS13080	COG0010	Belongs to the arginase family
MR74_RS13135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MR74_RS13135	COG2169	Transcriptional regulator
MR74_RS13145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MR74_RS13150	COG1846	Transcriptional regulator
MR74_RS13155	COG1764	response to oxidative stress
MR74_RS13190	COG0339	signal peptide processing
MR74_RS13200	COG2239	Acts as a magnesium transporter
MR74_RS13235	COG1349	DNA-binding transcription factor activity
MR74_RS13275	COG1129	ABC transporter
MR74_RS13295	COG1349	DNA-binding transcription factor activity
MR74_RS13305	COG0277	FAD linked oxidase domain protein
MR74_RS13310	COG1088	dTDP-glucose 4,6-dehydratase activity
MR74_RS13350	COG3586	endonuclease activity
MR74_RS13360	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MR74_RS13460	COG0789	Transcriptional regulator
MR74_RS13465	COG1993	acr, cog1993
MR74_RS13485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MR74_RS13500	COG1802	Transcriptional regulator
MR74_RS13515	COG0246	Mannitol dehydrogenase
MR74_RS13525	COG3842	ATPase activity
MR74_RS13530	COG1176	ABC-type spermidine putrescine transport system, permease component I
MR74_RS13535	COG4208	sulfate ABC transporter
MR74_RS13540	COG2721	sulfolactate sulfo-lyase activity
MR74_RS13555	COG0601	transmembrane transport
MR74_RS13560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MR74_RS13580	COG0583	DNA-binding transcription factor activity
MR74_RS13595	COG1960	acyl-CoA dehydrogenase activity
MR74_RS13600	COG0183	Belongs to the thiolase family
MR74_RS13630	COG0288	reversible hydration of carbon dioxide
MR74_RS13640	COG0747	negative chemotaxis
MR74_RS13655	COG0444	Belongs to the ABC transporter superfamily
MR74_RS13660	COG4172	Belongs to the ABC transporter superfamily
MR74_RS13675	COG0129	dihydroxy-acid dehydratase activity
MR74_RS13680	COG0363	glucosamine-6-phosphate deaminase activity
MR74_RS13685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MR74_RS13755	COG0583	DNA-binding transcription factor activity
MR74_RS13775	COG1846	Transcriptional regulator
MR74_RS13805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MR74_RS13810	COG1120	ATPase activity
MR74_RS13880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MR74_RS13905	COG1522	sequence-specific DNA binding
MR74_RS13915	COG1840	ABC-type Fe3 transport system, periplasmic component
MR74_RS13965	COG0673	inositol 2-dehydrogenase activity
MR74_RS13980	COG0450	alkyl hydroperoxide reductase
MR74_RS13990	COG0477	Major facilitator Superfamily
MR74_RS14020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MR74_RS14065	COG1175	transmembrane transport
MR74_RS14070	COG0395	ABC-type sugar transport system, permease component
MR74_RS14075	COG3842	ATPase activity
MR74_RS14085	COG0477	Major facilitator Superfamily
MR74_RS14100	COG0248	Ppx GppA phosphatase
MR74_RS14110	COG0765	amino acid transport
MR74_RS14115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MR74_RS14130	COG4604	ABC transporter, ATP-binding protein
MR74_RS14135	COG4605	iron ion homeostasis
MR74_RS14145	COG4607	ABC-type enterochelin transport system periplasmic component
MR74_RS14180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MR74_RS14205	COG2252	PERMEase
MR74_RS14225	COG0395	ABC-type sugar transport system, permease component
MR74_RS14250	COG3842	ATPase activity
MR74_RS14270	COG0683	leucine binding
MR74_RS14275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MR74_RS14280	COG3485	protocatechuate 3,4-dioxygenase
MR74_RS14285	COG3485	protocatechuate 3,4-dioxygenase
MR74_RS14290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MR74_RS14295	COG2267	carboxylic ester hydrolase activity
MR74_RS14300	COG0583	DNA-binding transcription factor activity
MR74_RS14315	COG1414	Transcriptional regulator
MR74_RS14325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MR74_RS14350	COG2176	DNA-directed DNA polymerase activity
MR74_RS14390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MR74_RS14395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MR74_RS14440	COG1754	DNA topoisomerase type I activity
MR74_RS14440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MR74_RS14445	COG0758	DNA mediated transformation
MR74_RS14455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MR74_RS14500	COG0187	DNA topoisomerase II activity
MR74_RS14545	COG0785	Cytochrome C biogenesis protein
MR74_RS14565	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MR74_RS14570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MR74_RS14575	COG0346	lactoylglutathione lyase activity
MR74_RS14605	COG1183	phosphatidylcholine synthase activity
MR74_RS14615	COG1129	ABC transporter
MR74_RS14660	COG1959	2 iron, 2 sulfur cluster binding
MR74_RS14665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MR74_RS14690	COG2963	transposase activity
MR74_RS14695	COG3436	PFAM IS66 Orf2 family protein
MR74_RS14760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MR74_RS14795	COG0601	transmembrane transport
MR74_RS14805	COG4172	Belongs to the ABC transporter superfamily
MR74_RS14810	COG3145	DNA-N1-methyladenine dioxygenase activity
MR74_RS14820	COG0477	Major facilitator Superfamily
MR74_RS14880	COG0673	inositol 2-dehydrogenase activity
MR74_RS14905	COG2971	BadF BadG BcrA BcrD
MR74_RS14910	COG2188	Transcriptional regulator
MR74_RS14930	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MR74_RS14955	COG2212	antiporter activity
MR74_RS14960	COG1863	multisubunit Na H antiporter MnhE subunit
MR74_RS14965	COG0651	ATP synthesis coupled electron transport
MR74_RS14970	COG1006	Multisubunit Na H antiporter MnhC subunit
MR74_RS14990	COG0521	Mo-molybdopterin cofactor biosynthetic process
MR74_RS15005	COG0156	8-amino-7-oxononanoate synthase activity
MR74_RS15015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MR74_RS15020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MR74_RS15055	COG1252	NADH dehydrogenase
MR74_RS15120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MR74_RS15200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MR74_RS15205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MR74_RS15215	COG0183	Belongs to the thiolase family
MR74_RS15220	COG1960	acyl-CoA dehydrogenase activity
MR74_RS15230	COG0583	DNA-binding transcription factor activity
MR74_RS15250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MR74_RS15270	COG4310	Domain of unknown function (DUF2172)
MR74_RS15290	COG0438	transferase activity, transferring glycosyl groups
MR74_RS15315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MR74_RS15335	COG0110	maltose O-acetyltransferase activity
MR74_RS15340	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MR74_RS15365	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MR74_RS15370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MR74_RS15385	COG2197	response regulator
MR74_RS15430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MR74_RS15475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MR74_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS15500	COG0604	alcohol dehydrogenase
MR74_RS15500	COG1028	Short-chain dehydrogenase reductase Sdr
MR74_RS15500	COG3321	synthase
MR74_RS15520	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MR74_RS15570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MR74_RS15570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MR74_RS15580	COG0753	catalase activity
MR74_RS15610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MR74_RS15630	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MR74_RS15655	COG0076	glutamate decarboxylase activity
MR74_RS15700	COG1177	transmembrane transport
MR74_RS15705	COG1176	ABC-type spermidine putrescine transport system, permease component I
MR74_RS15735	COG2894	cell division
MR74_RS15785	COG0673	inositol 2-dehydrogenase activity
MR74_RS15815	COG1609	Transcriptional regulator
MR74_RS15835	COG1140	nitrate reductase beta subunit
MR74_RS15850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MR74_RS15875	COG0826	peptidase U32
MR74_RS15890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MR74_RS15955	COG4178	(ABC) transporter
MR74_RS15965	COG5654	RES domain protein
MR74_RS16045	COG2151	metal-sulfur cluster biosynthetic enzyme
MR74_RS16070	COG0714	Associated with various cellular activities
MR74_RS16075	COG3256	nitric oxide reductase
MR74_RS16090	COG1845	cytochrome c oxidase, subunit III
MR74_RS16105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MR74_RS16110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MR74_RS16180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MR74_RS16185	COG1250	3-hydroxyacyl-CoA dehydrogenase
MR74_RS16190	COG1024	Enoyl-CoA hydratase
MR74_RS16200	COG1960	acyl-CoA dehydrogenase activity
MR74_RS16205	COG2814	Major facilitator Superfamily
MR74_RS16230	COG1519	Transferase
MR74_RS16250	COG0312	modulator of DNA gyrase
MR74_RS16255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MR74_RS16255	COG0475	glutathione-regulated potassium exporter activity
MR74_RS16265	COG0612	Peptidase, M16
MR74_RS16275	COG0742	ribosomal rna small subunit methyltransferase
MR74_RS16285	COG0590	tRNA wobble adenosine to inosine editing
MR74_RS16345	COG2259	Doxx family
MR74_RS16380	COG2818	Glycosylase
MR74_RS16385	COG1388	LysM domain
MR74_RS16385	COG1376	ErfK ybiS ycfS ynhG family protein
MR74_RS16400	COG0656	L-ascorbic acid biosynthetic process
MR74_RS16405	COG0656	L-ascorbic acid biosynthetic process
MR74_RS16410	COG0656	L-ascorbic acid biosynthetic process
MR74_RS16415	COG0247	lactate metabolic process
MR74_RS16425	COG0277	FAD linked oxidase domain protein
MR74_RS16430	COG0583	DNA-binding transcription factor activity
MR74_RS16435	COG2186	Transcriptional regulator
MR74_RS16470	COG3038	cytochrome b561
MR74_RS16485	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MR74_RS16495	COG0583	DNA-binding transcription factor activity
MR74_RS16515	COG1338	Plays a role in the flagellum-specific transport system
MR74_RS16535	COG1706	bacterial-type flagellum-dependent cell motility
MR74_RS16540	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MR74_RS16555	COG1558	bacterial-type flagellum-dependent cell motility
MR74_RS16560	COG1815	bacterial-type flagellum-dependent cell motility
MR74_RS16565	COG2084	Dehydrogenase
MR74_RS16575	COG3622	Belongs to the hyi family
MR74_RS16580	COG1349	DNA-binding transcription factor activity
MR74_RS16585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MR74_RS16590	COG0235	Class ii aldolase
MR74_RS16595	COG2271	Major facilitator Superfamily
MR74_RS16600	COG2963	transposase activity
MR74_RS16615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MR74_RS16640	COG0671	phosphoesterase, PA-phosphatase related
MR74_RS16650	COG1157	protein secretion by the type III secretion system
MR74_RS16655	COG4786	Flagellar basal body rod
MR74_RS16665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MR74_RS16680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MR74_RS16685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MR74_RS16690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MR74_RS16705	COG1309	transcriptional regulator
MR74_RS16750	COG0673	inositol 2-dehydrogenase activity
MR74_RS16785	COG0489	protein tyrosine kinase activity
MR74_RS16785	COG3206	protein involved in exopolysaccharide biosynthesis
MR74_RS16795	COG0154	amidase activity
MR74_RS16810	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MR74_RS16920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MR74_RS16995	COG1477	protein flavinylation