locus-tag	class	description
BMEA_RS00025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMEA_RS00030	COG4172	Belongs to the ABC transporter superfamily
BMEA_RS00035	COG4239	(ABC) transporter, permease
BMEA_RS00040	COG4174	ABC transporter (Permease)
BMEA_RS00050	COG4166	transmembrane transport
BMEA_RS00065	COG0683	leucine binding
BMEA_RS00075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BMEA_RS00090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BMEA_RS00095	COG1960	acyl-CoA dehydrogenase activity
BMEA_RS00135	COG0539	negative regulation of cytoplasmic translation
BMEA_RS00140	COG2855	membrane
BMEA_RS00145	COG0583	DNA-binding transcription factor activity
BMEA_RS00150	COG2951	lytic endotransglycosylase activity
BMEA_RS00165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BMEA_RS00175	COG2816	NAD+ diphosphatase activity
BMEA_RS00180	COG0077	Prephenate dehydratase
BMEA_RS00180	COG1605	Chorismate mutase
BMEA_RS00190	COG3474	cytochrome
BMEA_RS00200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BMEA_RS00205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BMEA_RS00210	COG1845	cytochrome c oxidase, subunit III
BMEA_RS00215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BMEA_RS00260	COG0346	lactoylglutathione lyase activity
BMEA_RS00265	COG0489	protein tyrosine kinase activity
BMEA_RS00270	COG0033	Phosphoglucomutase
BMEA_RS00280	COG1073	alpha beta
BMEA_RS00285	COG1072	(Pantothenic acid kinase))
BMEA_RS00315	COG1272	protein, Hemolysin III
BMEA_RS00320	COG0587	DNA-directed DNA polymerase activity
BMEA_RS00380	COG3339	Conserved Protein
BMEA_RS00395	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BMEA_RS00410	COG4181	ATPase activity
BMEA_RS00420	COG0670	Belongs to the BI1 family
BMEA_RS00440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BMEA_RS00445	COG4133	protoheme IX ABC transporter activity
BMEA_RS00450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BMEA_RS00455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BMEA_RS00465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMEA_RS00505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BMEA_RS00515	COG4208	sulfate ABC transporter
BMEA_RS00520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BMEA_RS00525	COG3459	Glycosyltransferase 36 associated
BMEA_RS00535	COG0384	phenazine biosynthesis protein PhzF
BMEA_RS00540	COG2226	methyltransferase
BMEA_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS00555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BMEA_RS00570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BMEA_RS00575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BMEA_RS00580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BMEA_RS00580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BMEA_RS00605	COG2153	protein acetylation
BMEA_RS00625	COG1643	Atp-dependent helicase
BMEA_RS00635	COG3293	Transposase
BMEA_RS00640	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BMEA_RS00650	COG1376	ErfK ybiS ycfS ynhG family protein
BMEA_RS00650	COG1388	LysM domain
BMEA_RS00655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BMEA_RS00665	COG0180	Tryptophanyl-tRNA synthetase
BMEA_RS00670	COG0728	peptidoglycan biosynthetic process
BMEA_RS00680	COG0281	malic enzyme
BMEA_RS00680	COG0280	phosphate acetyltransferase
BMEA_RS00690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BMEA_RS00705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMEA_RS00725	COG0616	signal peptide processing
BMEA_RS00735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BMEA_RS00740	COG1137	ATPase activity
BMEA_RS00745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BMEA_RS00750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BMEA_RS00755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMEA_RS00765	COG0071	Belongs to the small heat shock protein (HSP20) family
BMEA_RS00785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMEA_RS00790	COG2860	membrane
BMEA_RS00820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BMEA_RS00825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BMEA_RS00830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BMEA_RS00840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BMEA_RS00840	COG1648	precorrin-2 dehydrogenase activity
BMEA_RS00850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BMEA_RS00855	COG0175	sulfate reduction
BMEA_RS00870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BMEA_RS00890	COG2197	response regulator
BMEA_RS00895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BMEA_RS00910	COG1218	3'(2'),5'-bisphosphate nucleotidase
BMEA_RS00925	COG2197	response regulator
BMEA_RS00945	COG1012	belongs to the aldehyde dehydrogenase family
BMEA_RS00975	COG1012	belongs to the aldehyde dehydrogenase family
BMEA_RS00980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BMEA_RS00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BMEA_RS00990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BMEA_RS01015	COG0351	phosphomethylpyrimidine kinase
BMEA_RS01020	COG5001	Diguanylate cyclase
BMEA_RS01035	COG1174	glycine betaine transport
BMEA_RS01040	COG1125	glycine betaine transport
BMEA_RS01045	COG1174	glycine betaine transport
BMEA_RS01050	COG1732	Glycine betaine
BMEA_RS01060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BMEA_RS01075	COG0446	pyridine nucleotide-disulphide oxidoreductase
BMEA_RS01075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BMEA_RS01090	COG1414	Transcriptional regulator
BMEA_RS01100	COG1175	transmembrane transport
BMEA_RS01105	COG0395	ABC-type sugar transport system, permease component
BMEA_RS01110	COG3842	ATPase activity
BMEA_RS01115	COG4948	Mandelate Racemase Muconate Lactonizing
BMEA_RS01120	COG3254	rhamnose metabolic process
BMEA_RS01135	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS01145	COG4948	Mandelate Racemase Muconate Lactonizing
BMEA_RS01160	COG0582	viral genome integration into host DNA
BMEA_RS01305	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BMEA_RS01320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BMEA_RS01330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BMEA_RS01360	COG3617	BRO family, N-terminal domain
BMEA_RS01365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BMEA_RS01385	COG0829	nickel cation binding
BMEA_RS01405	COG0804	urea catabolic process
BMEA_RS01415	COG0830	nickel cation binding
BMEA_RS01430	COG4191	Histidine kinase
BMEA_RS01435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMEA_RS01440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMEA_RS01460	COG0494	nUDIX hydrolase
BMEA_RS01470	COG0493	'glutamate synthase
BMEA_RS01500	COG0318	PFAM AMP-dependent synthetase and ligase
BMEA_RS01535	COG2326	polyphosphate kinase activity
BMEA_RS01540	COG5002	protein histidine kinase activity
BMEA_RS01550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BMEA_RS01560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BMEA_RS01580	COG0717	Belongs to the dCTP deaminase family
BMEA_RS01600	COG0534	Mate efflux family protein
BMEA_RS01630	COG0784	Response regulator, receiver
BMEA_RS01630	COG2205	protein histidine kinase activity
BMEA_RS01630	COG2198	Histidine kinase
BMEA_RS01640	COG0156	8-amino-7-oxononanoate synthase activity
BMEA_RS01665	COG0583	DNA-binding transcription factor activity
BMEA_RS01670	COG1380	Effector of murein hydrolase LrgA
BMEA_RS01675	COG1346	cytolysis
BMEA_RS01705	COG0019	diaminopimelate decarboxylase activity
BMEA_RS01725	COG5342	invasion associated locus B
BMEA_RS01745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BMEA_RS01750	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BMEA_RS01755	COG3257	ureidoglycine aminohydrolase activity
BMEA_RS01760	COG3195	allantoin biosynthetic process
BMEA_RS01760	COG3648	Uricase
BMEA_RS01770	COG2080	2 iron, 2 sulfur cluster binding
BMEA_RS01775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BMEA_RS01785	COG0583	DNA-binding transcription factor activity
BMEA_RS01795	COG0402	S-adenosylhomocysteine deaminase activity
BMEA_RS01855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BMEA_RS01855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BMEA_RS01865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BMEA_RS01865	COG2169	Transcriptional regulator
BMEA_RS01870	COG1393	Belongs to the ArsC family
BMEA_RS01880	COG0477	Major facilitator Superfamily
BMEA_RS01885	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BMEA_RS01910	COG3773	Cell wall hydrolase
BMEA_RS01930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BMEA_RS01960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BMEA_RS01970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BMEA_RS01970	COG0616	signal peptide processing
BMEA_RS01985	COG0142	geranyltranstransferase activity
BMEA_RS02000	COG0751	glycine-tRNA ligase activity
BMEA_RS02005	COG0009	L-threonylcarbamoyladenylate synthase
BMEA_RS02035	COG1960	acyl-CoA dehydrogenase activity
BMEA_RS02050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BMEA_RS02065	COG0484	heat shock protein binding
BMEA_RS02070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BMEA_RS02080	COG1278	Cold shock
BMEA_RS02110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BMEA_RS02110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BMEA_RS02115	COG0123	including yeast histone deacetylase and acetoin utilization protein
BMEA_RS02120	COG1722	exodeoxyribonuclease VII activity
BMEA_RS02140	COG1741	Belongs to the pirin family
BMEA_RS02150	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BMEA_RS02155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BMEA_RS02175	COG5265	(ABC) transporter
BMEA_RS02185	COG1183	phosphatidylcholine synthase activity
BMEA_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS02195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BMEA_RS02210	COG0305	Participates in initiation and elongation during chromosome replication
BMEA_RS02215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BMEA_RS02240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BMEA_RS02255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMEA_RS02260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BMEA_RS02265	COG1561	YicC-like family, N-terminal region
BMEA_RS02270	COG0194	GDP metabolic process
BMEA_RS02275	COG0312	modulator of DNA gyrase
BMEA_RS02285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BMEA_RS02290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BMEA_RS02325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BMEA_RS02340	COG0678	peroxiredoxin activity
BMEA_RS02340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BMEA_RS02360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BMEA_RS02365	COG0612	Peptidase, M16
BMEA_RS02380	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BMEA_RS02390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMEA_RS02400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BMEA_RS02410	COG1194	a g-specific adenine glycosylase
BMEA_RS02425	COG1196	nuclear chromosome segregation
BMEA_RS02440	COG0574	Belongs to the PEP-utilizing enzyme family
BMEA_RS02440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BMEA_RS02465	COG1268	BioY protein
BMEA_RS02475	COG2351	hydroxyisourate hydrolase activity
BMEA_RS02490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BMEA_RS02515	COG2801	Transposase and inactivated derivatives
BMEA_RS02545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BMEA_RS02575	COG3293	Transposase
BMEA_RS02585	COG2801	Transposase and inactivated derivatives
BMEA_RS02590	COG3293	Transposase
BMEA_RS02605	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BMEA_RS02605	COG0662	Cupin 2, conserved barrel domain protein
BMEA_RS02610	COG2942	2-epimerase
BMEA_RS02615	COG0438	transferase activity, transferring glycosyl groups
BMEA_RS02615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BMEA_RS02625	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMEA_RS02630	COG1879	ABC-type sugar transport system periplasmic component
BMEA_RS02640	COG0673	inositol 2-dehydrogenase activity
BMEA_RS02650	COG1070	Carbohydrate kinase
BMEA_RS02675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BMEA_RS02690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BMEA_RS02710	COG2186	Transcriptional regulator
BMEA_RS02715	COG2807	transmembrane transport
BMEA_RS02725	COG0433	COG0433 Predicted ATPase
BMEA_RS02730	COG1376	ErfK ybiS ycfS ynhG family protein
BMEA_RS02740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BMEA_RS02755	COG4957	zinc ion binding
BMEA_RS02765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BMEA_RS02775	COG0154	amidase activity
BMEA_RS02780	COG2166	iron-sulfur cluster assembly
BMEA_RS02790	COG2205	protein histidine kinase activity
BMEA_RS02820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BMEA_RS02835	COG4695	Portal protein
BMEA_RS02945	COG4235	cytochrome complex assembly
BMEA_RS02955	COG1138	Cytochrome C-type biogenesis protein
BMEA_RS02960	COG3088	subunit of a heme lyase
BMEA_RS02965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMEA_RS02970	COG0745	RESPONSE REGULATOR receiver
BMEA_RS02980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BMEA_RS02990	COG2202	Pas domain
BMEA_RS02990	COG2205	protein histidine kinase activity
BMEA_RS02995	COG0308	aminopeptidase N
BMEA_RS03010	COG1573	uracil-dna glycosylase
BMEA_RS03025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BMEA_RS03040	COG0625	glutathione transferase activity
BMEA_RS03075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BMEA_RS03080	COG4974	Belongs to the 'phage' integrase family
BMEA_RS03085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BMEA_RS03110	COG3743	rRNA binding
BMEA_RS03110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BMEA_RS03115	COG0741	lytic transglycosylase activity
BMEA_RS03155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BMEA_RS03160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BMEA_RS03165	COG2223	nitrite transmembrane transporter activity
BMEA_RS03170	COG2207	Transcriptional regulator
BMEA_RS03185	COG0681	Belongs to the peptidase S26 family
BMEA_RS03210	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BMEA_RS03220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BMEA_RS03240	COG0494	nUDIX hydrolase
BMEA_RS03265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BMEA_RS03275	COG0739	heme binding
BMEA_RS03285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BMEA_RS03290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMEA_RS03295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BMEA_RS03325	COG0488	(ABC) transporter
BMEA_RS03345	COG0314	molybdopterin synthase activity
BMEA_RS03350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BMEA_RS03355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BMEA_RS03370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BMEA_RS03390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BMEA_RS03400	COG0243	molybdopterin cofactor binding
BMEA_RS03410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BMEA_RS03420	COG0628	permease
BMEA_RS03440	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS03565	COG0626	cystathionine gamma-synthase activity
BMEA_RS03570	COG0671	phosphoesterase, PA-phosphatase related
BMEA_RS03575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMEA_RS03580	COG4597	amino acid ABC transporter
BMEA_RS03585	COG0765	amino acid transport
BMEA_RS03590	COG1126	abc transporter atp-binding protein
BMEA_RS03605	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BMEA_RS03615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BMEA_RS03630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BMEA_RS03645	COG0113	porphobilinogen synthase activity
BMEA_RS03665	COG2989	Protein conserved in bacteria
BMEA_RS03680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BMEA_RS03680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BMEA_RS03700	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BMEA_RS03705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BMEA_RS03785	COG0010	Belongs to the arginase family
BMEA_RS03815	COG3293	Transposase
BMEA_RS03860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BMEA_RS03880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BMEA_RS03885	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BMEA_RS03925	COG1007	ATP synthesis coupled electron transport
BMEA_RS03940	COG0346	lactoylglutathione lyase activity
BMEA_RS03995	COG0483	inositol monophosphate 1-phosphatase activity
BMEA_RS04000	COG2814	Major facilitator Superfamily
BMEA_RS04035	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BMEA_RS04060	COG2514	catechol 2,3-dioxygenase activity
BMEA_RS04065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BMEA_RS04085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMEA_RS04090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BMEA_RS04095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BMEA_RS04110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BMEA_RS04115	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BMEA_RS04120	COG3454	Phosphonate metabolism
BMEA_RS04125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BMEA_RS04130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BMEA_RS04135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BMEA_RS04160	COG1522	sequence-specific DNA binding
BMEA_RS04165	COG1573	uracil-dna glycosylase
BMEA_RS04190	COG0316	Belongs to the HesB IscA family
BMEA_RS04210	COG1472	Belongs to the glycosyl hydrolase 3 family
BMEA_RS04215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BMEA_RS04220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BMEA_RS04230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BMEA_RS04235	COG0805	protein transport
BMEA_RS04250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BMEA_RS04270	COG1862	Preprotein translocase
BMEA_RS04315	COG0544	peptidyl-prolyl cis-trans isomerase activity
BMEA_RS04335	COG4765	Protein conserved in bacteria
BMEA_RS04345	COG0439	Biotin carboxylase
BMEA_RS04350	COG0511	ligase activity, forming carbon-carbon bonds
BMEA_RS04365	COG0501	Belongs to the peptidase M48B family
BMEA_RS04370	COG0436	Aminotransferase
BMEA_RS04375	COG1530	ribonuclease E activity
BMEA_RS04385	COG0860	N-Acetylmuramoyl-L-alanine amidase
BMEA_RS04390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BMEA_RS04400	COG3293	Transposase
BMEA_RS04410	COG2833	Protein of unknown function (DUF455)
BMEA_RS04415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BMEA_RS04430	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BMEA_RS04440	COG2945	thiolester hydrolase activity
BMEA_RS04450	COG0719	Fe-S assembly protein
BMEA_RS04455	COG0396	ATPase activity
BMEA_RS04460	COG0719	Fe-S assembly protein
BMEA_RS04465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BMEA_RS04470	COG2151	metal-sulfur cluster biosynthetic enzyme
BMEA_RS04485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BMEA_RS04490	COG0513	Belongs to the DEAD box helicase family
BMEA_RS04495	COG0316	Belongs to the HesB IscA family
BMEA_RS04510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BMEA_RS04525	COG0525	valine-tRNA ligase activity
BMEA_RS04540	COG2084	Dehydrogenase
BMEA_RS04545	COG0625	glutathione transferase activity
BMEA_RS04590	COG2989	Protein conserved in bacteria
BMEA_RS04685	COG3293	Transposase
BMEA_RS04720	COG1393	Belongs to the ArsC family
BMEA_RS04750	COG0084	hydrolase, TatD family'
BMEA_RS04760	COG1132	(ABC) transporter
BMEA_RS04785	COG0174	glutamine synthetase
BMEA_RS04790	COG0347	Belongs to the P(II) protein family
BMEA_RS04795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BMEA_RS04795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BMEA_RS04805	COG0546	phosphoglycolate phosphatase activity
BMEA_RS04810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BMEA_RS04825	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BMEA_RS04830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BMEA_RS04840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BMEA_RS04840	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BMEA_RS04850	COG0280	phosphate acetyltransferase
BMEA_RS04850	COG0281	malic enzyme
BMEA_RS04855	COG4948	Mandelate Racemase Muconate Lactonizing
BMEA_RS04860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BMEA_RS04865	COG1127	ABC transporter
BMEA_RS04890	COG0633	Ferredoxin
BMEA_RS04895	COG0492	ferredoxin-NADP+ reductase activity
BMEA_RS04910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BMEA_RS04920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BMEA_RS04960	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BMEA_RS04970	COG0668	transmembrane transport
BMEA_RS04975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMEA_RS04995	COG1546	Belongs to the CinA family
BMEA_RS04995	COG1058	Belongs to the CinA family
BMEA_RS05010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BMEA_RS05015	COG0513	Belongs to the DEAD box helicase family
BMEA_RS05020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BMEA_RS05025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BMEA_RS05030	COG2897	thiosulfate sulfurtransferase activity
BMEA_RS05045	COG0427	acetyl-CoA hydrolase
BMEA_RS05050	COG2814	Major facilitator Superfamily
BMEA_RS05055	COG1566	PFAM secretion protein HlyD family protein
BMEA_RS05065	COG0006	proline dipeptidase activity
BMEA_RS05070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BMEA_RS05080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BMEA_RS05085	COG3956	TIGRFAM MazG family protein
BMEA_RS05090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BMEA_RS05115	COG1686	Belongs to the peptidase S11 family
BMEA_RS05140	COG1752	Esterase of the alpha-beta hydrolase superfamily
BMEA_RS05170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BMEA_RS05180	COG3617	BRO family, N-terminal domain
BMEA_RS05190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BMEA_RS05195	COG1960	acyl-CoA dehydrogenase activity
BMEA_RS05200	COG0583	DNA-binding transcription factor activity
BMEA_RS05205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMEA_RS05210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BMEA_RS05215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMEA_RS05255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BMEA_RS05260	COG2095	MarC family integral membrane protein
BMEA_RS05270	COG2188	Transcriptional regulator
BMEA_RS05280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BMEA_RS05290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BMEA_RS05305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BMEA_RS05320	COG0569	domain protein
BMEA_RS05325	COG2204	response regulator
BMEA_RS05330	COG5000	phosphorelay sensor kinase activity
BMEA_RS05335	COG2204	response regulator
BMEA_RS05340	COG3852	Histidine kinase
BMEA_RS05355	COG1058	Belongs to the CinA family
BMEA_RS05355	COG1546	Belongs to the CinA family
BMEA_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS05365	COG2867	negative regulation of translational initiation
BMEA_RS05380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BMEA_RS05385	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMEA_RS05390	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMEA_RS05390	COG0022	dehydrogenase e1 component
BMEA_RS05395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BMEA_RS05400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BMEA_RS05440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMEA_RS05460	COG0303	'Molybdopterin
BMEA_RS05470	COG2333	competence protein COMEC
BMEA_RS05470	COG0658	competence protein
BMEA_RS05480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BMEA_RS05485	COG0372	Belongs to the citrate synthase family
BMEA_RS05490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BMEA_RS05515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BMEA_RS05520	COG0750	zinc metalloprotease
BMEA_RS05540	COG0528	UMP kinase activity
BMEA_RS05570	COG0584	glycerophosphoryl diester phosphodiesterase
BMEA_RS05580	COG0537	adenosine 5'-monophosphoramidase activity
BMEA_RS05595	COG1686	Belongs to the peptidase S11 family
BMEA_RS05610	COG1760	l-serine dehydratase
BMEA_RS05660	COG3800	Transcriptional regulator
BMEA_RS05660	COG1396	sequence-specific DNA binding
BMEA_RS05665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BMEA_RS05670	COG4770	biotin carboxylase activity
BMEA_RS05675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BMEA_RS05675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BMEA_RS05690	COG2358	TRAP transporter, solute receptor (TAXI family
BMEA_RS05700	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BMEA_RS05705	COG0693	protein deglycase activity
BMEA_RS05715	COG0538	isocitrate dehydrogenase activity
BMEA_RS05720	COG1785	Belongs to the alkaline phosphatase family
BMEA_RS05735	COG2885	chlorophyll binding
BMEA_RS05745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BMEA_RS05750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BMEA_RS05795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BMEA_RS05860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BMEA_RS05950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BMEA_RS05975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BMEA_RS05980	COG0517	IMP dehydrogenase activity
BMEA_RS05980	COG0516	GMP reductase activity
BMEA_RS06010	COG3293	Transposase
BMEA_RS06050	COG1181	Belongs to the D-alanine--D-alanine ligase family
BMEA_RS06055	COG1494	fructose-1,6-bisphosphatase
BMEA_RS06065	COG0436	Aminotransferase
BMEA_RS06100	COG0024	Methionine aminopeptidase
BMEA_RS06155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BMEA_RS06165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BMEA_RS06270	COG0583	DNA-binding transcription factor activity
BMEA_RS06285	COG1053	succinate dehydrogenase
BMEA_RS06285	COG3976	FMN-binding domain protein
BMEA_RS06300	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BMEA_RS06300	COG3264	Mechanosensitive ion channel
BMEA_RS06315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BMEA_RS06315	COG4651	solute:proton antiporter activity
BMEA_RS06335	COG4208	sulfate ABC transporter
BMEA_RS06340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BMEA_RS06345	COG4150	thiosulfate binding
BMEA_RS06355	COG1253	flavin adenine dinucleotide binding
BMEA_RS06360	COG0586	Pfam SNARE associated Golgi protein
BMEA_RS06375	COG4154	Belongs to the RbsD FucU family
BMEA_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS06390	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMEA_RS06405	COG1120	ATPase activity
BMEA_RS06410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BMEA_RS06425	COG0842	Transport permease protein
BMEA_RS06435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMEA_RS06440	COG1649	PFAM Uncharacterised BCR, COG1649
BMEA_RS06455	COG0804	urea catabolic process
BMEA_RS06480	COG4413	Urea transporter
BMEA_RS06490	COG0310	cobalt ion transport
BMEA_RS06510	COG3439	Domain of unknown function DUF302
BMEA_RS06510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BMEA_RS06530	COG0384	phenazine biosynthesis protein PhzF
BMEA_RS06550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMEA_RS06585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BMEA_RS06590	COG0440	acetolactate synthase activity
BMEA_RS06595	COG0028	Belongs to the TPP enzyme family
BMEA_RS06605	COG0560	Phosphoserine phosphatase
BMEA_RS06625	COG0330	HflC and HflK could
BMEA_RS06650	COG2814	Major facilitator Superfamily
BMEA_RS06690	COG0277	FAD linked oxidase domain protein
BMEA_RS06705	COG0210	DNA helicase
BMEA_RS06720	COG1999	signal sequence binding
BMEA_RS06730	COG0006	proline dipeptidase activity
BMEA_RS06750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BMEA_RS06760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BMEA_RS06765	COG0849	cell division
BMEA_RS06770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BMEA_RS06775	COG1181	Belongs to the D-alanine--D-alanine ligase family
BMEA_RS06815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BMEA_RS06835	COG1914	H( )-stimulated, divalent metal cation uptake system
BMEA_RS06845	COG3023	N-Acetylmuramoyl-L-alanine amidase
BMEA_RS06850	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BMEA_RS06880	COG0640	Transcriptional regulator
BMEA_RS06890	COG0477	Major facilitator Superfamily
BMEA_RS06910	COG2267	carboxylic ester hydrolase activity
BMEA_RS06930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BMEA_RS06935	COG2824	Alkylphosphonate utilization operon protein PhnA
BMEA_RS06940	COG1335	isochorismatase
BMEA_RS06955	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BMEA_RS06995	COG2968	Membrane
BMEA_RS07015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BMEA_RS07020	COG0358	DNA primase activity
BMEA_RS07040	COG2321	neutral zinc metallopeptidase
BMEA_RS07055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BMEA_RS07060	COG1136	(ABC) transporter
BMEA_RS07070	COG1278	Cold shock
BMEA_RS07075	COG0625	glutathione transferase activity
BMEA_RS07080	COG0436	Aminotransferase
BMEA_RS07095	COG0583	DNA-binding transcription factor activity
BMEA_RS07100	COG0492	ferredoxin-NADP+ reductase activity
BMEA_RS07105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BMEA_RS07110	COG1522	sequence-specific DNA binding
BMEA_RS07155	COG0556	nucleotide-excision repair
BMEA_RS07160	COG1196	nuclear chromosome segregation
BMEA_RS07160	COG0739	heme binding
BMEA_RS07160	COG0741	lytic transglycosylase activity
BMEA_RS07165	COG1278	Cold shock
BMEA_RS07175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BMEA_RS07195	COG1846	Transcriptional regulator
BMEA_RS07200	COG0745	RESPONSE REGULATOR receiver
BMEA_RS07205	COG2205	protein histidine kinase activity
BMEA_RS07215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BMEA_RS07240	COG1496	oxidoreductase activity
BMEA_RS07260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BMEA_RS07280	COG0012	GTP binding
BMEA_RS07285	COG2030	dehydratase
BMEA_RS07300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BMEA_RS07300	COG2857	Cytochrome c1
BMEA_RS07315	COG1132	(ABC) transporter
BMEA_RS07320	COG1132	(ABC) transporter
BMEA_RS07325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BMEA_RS07345	COG3153	acetyltransferase
BMEA_RS07360	COG0617	tRNA 3'-terminal CCA addition
BMEA_RS07375	COG0714	Associated with various cellular activities
BMEA_RS07400	COG0435	Glutathione S-transferase
BMEA_RS07405	COG3047	cAMP biosynthetic process
BMEA_RS07410	COG1051	belongs to the nudix hydrolase family
BMEA_RS07420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BMEA_RS07425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BMEA_RS07430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BMEA_RS07430	COG0512	Glutamine amidotransferase of anthranilate synthase
BMEA_RS07440	COG1522	sequence-specific DNA binding
BMEA_RS07470	COG4176	ABC-type proline glycine betaine transport system permease component
BMEA_RS07475	COG4175	Glycine betaine
BMEA_RS07480	COG4608	Belongs to the ABC transporter superfamily
BMEA_RS07485	COG0444	Belongs to the ABC transporter superfamily
BMEA_RS07490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BMEA_RS07495	COG0601	transmembrane transport
BMEA_RS07595	COG2205	protein histidine kinase activity
BMEA_RS07605	COG1177	transmembrane transport
BMEA_RS07610	COG1176	ABC-type spermidine putrescine transport system, permease component I
BMEA_RS07615	COG3842	ATPase activity
BMEA_RS07625	COG3800	Transcriptional regulator
BMEA_RS07625	COG1396	sequence-specific DNA binding
BMEA_RS07630	COG3800	Transcriptional regulator
BMEA_RS07630	COG1396	sequence-specific DNA binding
BMEA_RS07635	COG2224	Isocitrate lyase
BMEA_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS07670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BMEA_RS07685	COG1461	Dihydroxyacetone kinase
BMEA_RS07690	COG2376	Dihydroxyacetone kinase
BMEA_RS07695	COG1461	Dihydroxyacetone kinase
BMEA_RS07700	COG2376	Dihydroxyacetone kinase
BMEA_RS07710	COG1879	ABC-type sugar transport system periplasmic component
BMEA_RS07715	COG1172	Belongs to the binding-protein-dependent transport system permease family
BMEA_RS07720	COG1129	ABC transporter
BMEA_RS07775	COG1012	belongs to the aldehyde dehydrogenase family
BMEA_RS07800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BMEA_RS07815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BMEA_RS07820	COG0564	pseudouridine synthase activity
BMEA_RS07835	COG0735	belongs to the Fur family
BMEA_RS07850	COG0784	Response regulator, receiver
BMEA_RS07865	COG3920	Histidine kinase
BMEA_RS07900	COG0848	biopolymer transport protein
BMEA_RS07915	COG4591	ABC-type transport system involved in lipoprotein release permease component
BMEA_RS07915	COG1136	(ABC) transporter
BMEA_RS07920	COG4591	ABC-type transport system involved in lipoprotein release permease component
BMEA_RS07920	COG1136	(ABC) transporter
BMEA_RS07925	COG4591	ABC-type transport system involved in lipoprotein release permease component
BMEA_RS07925	COG1136	(ABC) transporter
BMEA_RS07930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BMEA_RS07940	COG1522	sequence-specific DNA binding
BMEA_RS07965	COG0477	Major facilitator Superfamily
BMEA_RS07985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BMEA_RS07995	COG0385	Bile acid
BMEA_RS08005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BMEA_RS08010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BMEA_RS08030	COG2885	chlorophyll binding
BMEA_RS08045	COG0848	biopolymer transport protein
BMEA_RS08055	COG0824	Thioesterase
BMEA_RS08100	COG0483	inositol monophosphate 1-phosphatase activity
BMEA_RS08115	COG1132	(ABC) transporter
BMEA_RS08145	COG1253	flavin adenine dinucleotide binding
BMEA_RS08150	COG1692	metallophosphoesterase
BMEA_RS08215	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS08215	COG3321	synthase
BMEA_RS08215	COG0604	alcohol dehydrogenase
BMEA_RS08240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BMEA_RS08245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BMEA_RS08255	COG0457	Tetratricopeptide repeat
BMEA_RS08260	COG0469	pyruvate kinase activity
BMEA_RS08275	COG3750	Belongs to the UPF0335 family
BMEA_RS08280	COG0488	(ABC) transporter
BMEA_RS08295	COG4143	(ABC) transporter
BMEA_RS08300	COG1178	ABC-type Fe3 transport system permease component
BMEA_RS08315	COG2258	MOSC domain
BMEA_RS08320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BMEA_RS08325	COG1329	Transcriptional regulator
BMEA_RS08330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BMEA_RS08345	COG0183	Belongs to the thiolase family
BMEA_RS08365	COG0142	geranyltranstransferase activity
BMEA_RS08375	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS08380	COG0738	Major facilitator superfamily
BMEA_RS08385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BMEA_RS08395	COG0683	leucine binding
BMEA_RS08425	COG3938	Belongs to the proline racemase family
BMEA_RS08495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BMEA_RS08505	COG5425	PFAM Usg family protein
BMEA_RS08525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BMEA_RS08525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BMEA_RS08540	COG2270	Major facilitator Superfamily
BMEA_RS08555	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BMEA_RS08560	COG1704	LemA family
BMEA_RS08570	COG0287	Prephenate dehydrogenase
BMEA_RS08570	COG1605	Chorismate mutase
BMEA_RS08575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BMEA_RS08585	COG0288	reversible hydration of carbon dioxide
BMEA_RS08625	COG0793	Belongs to the peptidase S41A family
BMEA_RS08645	COG0799	negative regulation of ribosome biogenesis
BMEA_RS08710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BMEA_RS08765	COG0739	heme binding
BMEA_RS08775	COG0542	response to heat
BMEA_RS08785	COG2890	protein-(glutamine-N5) methyltransferase activity
BMEA_RS08800	COG0527	aspartate kinase activity
BMEA_RS08830	COG1040	competence protein
BMEA_RS08835	COG2226	methyltransferase
BMEA_RS08890	COG2264	protein methyltransferase activity
BMEA_RS08895	COG0697	spore germination
BMEA_RS08900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BMEA_RS08905	COG1674	ftsk spoiiie
BMEA_RS08910	COG0004	ammonium transporteR
BMEA_RS08915	COG1946	Acyl-CoA thioesterase
BMEA_RS08920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BMEA_RS08965	COG1953	Uracil, thiamine, allantoin
BMEA_RS09025	COG1280	lysine exporter protein (LysE YggA)
BMEA_RS09035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BMEA_RS09045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BMEA_RS09060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BMEA_RS09075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BMEA_RS09080	COG0552	protein localization to endoplasmic reticulum
BMEA_RS09105	COG0494	nUDIX hydrolase
BMEA_RS09115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BMEA_RS09120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BMEA_RS09145	COG2194	sulfuric ester hydrolase activity
BMEA_RS09175	COG0765	amino acid transport
BMEA_RS09180	COG0765	amino acid transport
BMEA_RS09200	COG1126	abc transporter atp-binding protein
BMEA_RS09210	COG1802	Transcriptional regulator
BMEA_RS09215	COG0252	asparaginase activity
BMEA_RS09240	COG1250	3-hydroxyacyl-CoA dehydrogenase
BMEA_RS09245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BMEA_RS09250	COG2086	electron transfer activity
BMEA_RS09260	COG0720	synthase
BMEA_RS09265	COG0602	queuosine metabolic process
BMEA_RS09280	COG0300	oxidoreductase activity
BMEA_RS09295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BMEA_RS09325	COG2226	methyltransferase
BMEA_RS09330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BMEA_RS09335	COG0287	Prephenate dehydrogenase
BMEA_RS09360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BMEA_RS09380	COG2884	Cell division ATP-binding protein ftsE
BMEA_RS09390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BMEA_RS09395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BMEA_RS09455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BMEA_RS09470	COG0789	Transcriptional regulator
BMEA_RS09475	COG2217	Heavy metal translocating P-type atpase
BMEA_RS09510	COG4536	flavin adenine dinucleotide binding
BMEA_RS09530	COG4974	Belongs to the 'phage' integrase family
BMEA_RS09550	COG0523	cobalamin synthesis protein
BMEA_RS09555	COG1686	Belongs to the peptidase S11 family
BMEA_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
BMEA_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
BMEA_RS09605	COG1024	Enoyl-CoA hydratase
BMEA_RS09630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BMEA_RS09640	COG4120	Belongs to the binding-protein-dependent transport system permease family
BMEA_RS09645	COG1122	ATPase activity
BMEA_RS09675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BMEA_RS09685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BMEA_RS09695	COG1981	membrane
BMEA_RS09710	COG0424	maF-like protein
BMEA_RS09720	COG0237	dephospho-CoA kinase activity
BMEA_RS09740	COG4395	Tim44
BMEA_RS09750	COG2840	Smr protein MutS2
BMEA_RS09755	COG1396	sequence-specific DNA binding
BMEA_RS09785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BMEA_RS09820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BMEA_RS09825	COG0745	RESPONSE REGULATOR receiver
BMEA_RS09830	COG2205	protein histidine kinase activity
BMEA_RS09840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMEA_RS09840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BMEA_RS09845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BMEA_RS09855	COG2205	protein histidine kinase activity
BMEA_RS09860	COG3178	'Phosphotransferase
BMEA_RS09865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BMEA_RS09870	COG2887	Belongs to the helicase family. UvrD subfamily
BMEA_RS09875	COG1074	ATP-dependent DNA helicase activity
BMEA_RS09885	COG0285	dihydrofolate synthase activity
BMEA_RS09915	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BMEA_RS09935	COG3135	benzoate transporter
BMEA_RS09950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BMEA_RS10005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BMEA_RS10020	COG3386	PFAM SMP-30 Gluconolaconase
BMEA_RS10025	COG0189	ligase activity
BMEA_RS10030	COG0606	chelatase, subunit chli
BMEA_RS10040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BMEA_RS10045	COG2832	Protein of unknown function (DUF454)
BMEA_RS10050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BMEA_RS10055	COG0573	inorganic phosphate transmembrane transporter activity
BMEA_RS10065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BMEA_RS10070	COG0704	Plays a role in the regulation of phosphate uptake
BMEA_RS10075	COG0745	RESPONSE REGULATOR receiver
BMEA_RS10080	COG3773	Cell wall hydrolase
BMEA_RS10090	COG2309	aminopeptidase activity
BMEA_RS10095	COG0783	Belongs to the Dps family
BMEA_RS10105	COG0456	acetyltransferase
BMEA_RS10115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BMEA_RS10135	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BMEA_RS10140	COG1396	sequence-specific DNA binding
BMEA_RS10145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BMEA_RS10150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BMEA_RS10160	COG0195	Participates in both transcription termination and antitermination
BMEA_RS10160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BMEA_RS10180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BMEA_RS10195	COG2813	Specifically methylates the guanine in position
BMEA_RS10200	COG2813	Specifically methylates the guanine in position
BMEA_RS10205	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BMEA_RS10245	COG0791	NLP P60 protein
BMEA_RS10255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BMEA_RS10270	COG1024	Enoyl-CoA hydratase
BMEA_RS10610	COG0033	Phosphoglucomutase
BMEA_RS11005	COG1643	Atp-dependent helicase
BMEA_RS11030	COG2205	protein histidine kinase activity
BMEA_RS11150	COG1137	ATPase activity
BMEA_RS11160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BMEA_RS11420	COG2217	Heavy metal translocating P-type atpase
BMEA_RS12520	COG5265	(ABC) transporter
BMEA_RS12795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BMEA_RS12795	COG0574	Belongs to the PEP-utilizing enzyme family
BMEA_RS12810	COG0574	Belongs to the PEP-utilizing enzyme family
BMEA_RS12810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BMEA_RS13290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BMEA_RS13425	COG0741	lytic transglycosylase activity
BMEA_RS14270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BMEA_RS14355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BMEA_RS14665	COG0719	Fe-S assembly protein
BMEA_RS14960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BMEA_RS14960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BMEA_RS14995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BMEA_RS15025	COG0280	phosphate acetyltransferase
BMEA_RS15025	COG0281	malic enzyme
BMEA_RS15170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMEA_RS15185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BMEA_RS15475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BMEA_RS15550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BMEA_RS15600	COG5000	phosphorelay sensor kinase activity
BMEA_RS15610	COG2204	response regulator
BMEA_RS15870	COG4770	biotin carboxylase activity