locus-tag	class	description
ADS42_RS00035	COG0346	lactoylglutathione lyase activity
ADS42_RS00055	COG1494	fructose-1,6-bisphosphatase
ADS42_RS00065	COG0436	Aminotransferase
ADS42_RS00100	COG0024	Methionine aminopeptidase
ADS42_RS00155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADS42_RS00165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ADS42_RS00275	COG0583	DNA-binding transcription factor activity
ADS42_RS00300	COG3264	Mechanosensitive ion channel
ADS42_RS00300	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ADS42_RS00315	COG4651	solute:proton antiporter activity
ADS42_RS00315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADS42_RS00335	COG4208	sulfate ABC transporter
ADS42_RS00340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADS42_RS00345	COG4150	thiosulfate binding
ADS42_RS00355	COG1253	flavin adenine dinucleotide binding
ADS42_RS00360	COG0586	Pfam SNARE associated Golgi protein
ADS42_RS00380	COG4154	Belongs to the RbsD FucU family
ADS42_RS00385	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS00395	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADS42_RS00410	COG1120	ATPase activity
ADS42_RS00415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADS42_RS00430	COG0842	Transport permease protein
ADS42_RS00440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADS42_RS00455	COG1649	PFAM Uncharacterised BCR, COG1649
ADS42_RS00470	COG0804	urea catabolic process
ADS42_RS00495	COG4413	Urea transporter
ADS42_RS00505	COG0310	cobalt ion transport
ADS42_RS00525	COG3439	Domain of unknown function DUF302
ADS42_RS00525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADS42_RS00545	COG0384	phenazine biosynthesis protein PhzF
ADS42_RS00565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADS42_RS00585	COG3158	transport of potassium into the cell
ADS42_RS00600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADS42_RS00605	COG0440	acetolactate synthase activity
ADS42_RS00610	COG0028	Belongs to the TPP enzyme family
ADS42_RS00625	COG0560	Phosphoserine phosphatase
ADS42_RS00645	COG0330	HflC and HflK could
ADS42_RS00680	COG2814	Major facilitator Superfamily
ADS42_RS00710	COG0277	FAD linked oxidase domain protein
ADS42_RS00725	COG0210	DNA helicase
ADS42_RS00740	COG1999	signal sequence binding
ADS42_RS00750	COG0006	proline dipeptidase activity
ADS42_RS00770	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADS42_RS00785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADS42_RS00790	COG0849	cell division
ADS42_RS00795	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADS42_RS00800	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADS42_RS00840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADS42_RS00865	COG1914	H( )-stimulated, divalent metal cation uptake system
ADS42_RS00880	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADS42_RS00885	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADS42_RS00915	COG0640	Transcriptional regulator
ADS42_RS00925	COG0477	Major facilitator Superfamily
ADS42_RS00950	COG2267	carboxylic ester hydrolase activity
ADS42_RS00975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADS42_RS00980	COG2824	Alkylphosphonate utilization operon protein PhnA
ADS42_RS00985	COG1335	isochorismatase
ADS42_RS01010	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ADS42_RS01050	COG2968	Membrane
ADS42_RS01070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADS42_RS01080	COG0358	DNA primase activity
ADS42_RS01100	COG2321	neutral zinc metallopeptidase
ADS42_RS01115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADS42_RS01125	COG1136	(ABC) transporter
ADS42_RS01135	COG1278	Cold shock
ADS42_RS01140	COG0625	glutathione transferase activity
ADS42_RS01145	COG0436	Aminotransferase
ADS42_RS01160	COG0583	DNA-binding transcription factor activity
ADS42_RS01165	COG0492	ferredoxin-NADP+ reductase activity
ADS42_RS01170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADS42_RS01175	COG1522	sequence-specific DNA binding
ADS42_RS01225	COG0556	nucleotide-excision repair
ADS42_RS01230	COG0741	lytic transglycosylase activity
ADS42_RS01230	COG1196	nuclear chromosome segregation
ADS42_RS01230	COG0739	heme binding
ADS42_RS01235	COG1278	Cold shock
ADS42_RS01250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADS42_RS01270	COG1846	Transcriptional regulator
ADS42_RS01275	COG0745	RESPONSE REGULATOR receiver
ADS42_RS01280	COG2205	protein histidine kinase activity
ADS42_RS01290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADS42_RS01325	COG1496	oxidoreductase activity
ADS42_RS01345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADS42_RS01365	COG0012	GTP binding
ADS42_RS01370	COG2030	dehydratase
ADS42_RS01385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ADS42_RS01385	COG2857	Cytochrome c1
ADS42_RS01400	COG1132	(ABC) transporter
ADS42_RS01405	COG1132	(ABC) transporter
ADS42_RS01410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ADS42_RS01430	COG3153	acetyltransferase
ADS42_RS01445	COG0617	tRNA 3'-terminal CCA addition
ADS42_RS01460	COG0714	Associated with various cellular activities
ADS42_RS01485	COG0435	Glutathione S-transferase
ADS42_RS01490	COG3047	cAMP biosynthetic process
ADS42_RS01495	COG1051	belongs to the nudix hydrolase family
ADS42_RS01505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADS42_RS01510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADS42_RS01520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADS42_RS01520	COG0512	Glutamine amidotransferase of anthranilate synthase
ADS42_RS01530	COG1522	sequence-specific DNA binding
ADS42_RS01560	COG4176	ABC-type proline glycine betaine transport system permease component
ADS42_RS01565	COG4175	Glycine betaine
ADS42_RS01570	COG4608	Belongs to the ABC transporter superfamily
ADS42_RS01575	COG0444	Belongs to the ABC transporter superfamily
ADS42_RS01580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADS42_RS01585	COG0601	transmembrane transport
ADS42_RS01695	COG2205	protein histidine kinase activity
ADS42_RS01715	COG1177	transmembrane transport
ADS42_RS01720	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADS42_RS01725	COG3842	ATPase activity
ADS42_RS01745	COG2224	Isocitrate lyase
ADS42_RS01760	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS01765	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS01780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ADS42_RS01795	COG1461	Dihydroxyacetone kinase
ADS42_RS01805	COG2390	Transcriptional regulator
ADS42_RS01810	COG1461	Dihydroxyacetone kinase
ADS42_RS01815	COG2376	Dihydroxyacetone kinase
ADS42_RS01825	COG1879	ABC-type sugar transport system periplasmic component
ADS42_RS01830	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADS42_RS01835	COG1129	ABC transporter
ADS42_RS01890	COG1012	belongs to the aldehyde dehydrogenase family
ADS42_RS01915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADS42_RS01930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADS42_RS01935	COG0564	pseudouridine synthase activity
ADS42_RS01950	COG0735	belongs to the Fur family
ADS42_RS01970	COG0784	Response regulator, receiver
ADS42_RS01990	COG3920	Histidine kinase
ADS42_RS02020	COG0848	biopolymer transport protein
ADS42_RS02035	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADS42_RS02035	COG1136	(ABC) transporter
ADS42_RS02045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADS42_RS02055	COG1522	sequence-specific DNA binding
ADS42_RS02075	COG0477	Major facilitator Superfamily
ADS42_RS02095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADS42_RS02105	COG0385	Bile acid
ADS42_RS02115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADS42_RS02120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADS42_RS02135	COG2885	chlorophyll binding
ADS42_RS02155	COG0848	biopolymer transport protein
ADS42_RS02165	COG0824	Thioesterase
ADS42_RS02210	COG0483	inositol monophosphate 1-phosphatase activity
ADS42_RS02225	COG1132	(ABC) transporter
ADS42_RS02255	COG1253	flavin adenine dinucleotide binding
ADS42_RS02260	COG1692	metallophosphoesterase
ADS42_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS02365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADS42_RS02370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADS42_RS02380	COG0457	Tetratricopeptide repeat
ADS42_RS02385	COG0469	pyruvate kinase activity
ADS42_RS02400	COG3750	Belongs to the UPF0335 family
ADS42_RS02405	COG0488	(ABC) transporter
ADS42_RS02425	COG4143	(ABC) transporter
ADS42_RS02430	COG1178	ABC-type Fe3 transport system permease component
ADS42_RS02445	COG2258	MOSC domain
ADS42_RS02450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADS42_RS02465	COG1329	Transcriptional regulator
ADS42_RS02470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ADS42_RS02490	COG0183	Belongs to the thiolase family
ADS42_RS02510	COG0142	geranyltranstransferase activity
ADS42_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS02525	COG0738	Major facilitator superfamily
ADS42_RS02530	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ADS42_RS02540	COG0683	leucine binding
ADS42_RS02570	COG3938	Belongs to the proline racemase family
ADS42_RS02645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADS42_RS02655	COG5425	PFAM Usg family protein
ADS42_RS02675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADS42_RS02675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADS42_RS02705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ADS42_RS02710	COG1704	LemA family
ADS42_RS02720	COG1605	Chorismate mutase
ADS42_RS02720	COG0287	Prephenate dehydrogenase
ADS42_RS02725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADS42_RS02740	COG0288	reversible hydration of carbon dioxide
ADS42_RS02780	COG0793	Belongs to the peptidase S41A family
ADS42_RS02800	COG0799	negative regulation of ribosome biogenesis
ADS42_RS02865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADS42_RS02925	COG0739	heme binding
ADS42_RS02950	COG2890	protein-(glutamine-N5) methyltransferase activity
ADS42_RS02965	COG0527	aspartate kinase activity
ADS42_RS02995	COG1040	competence protein
ADS42_RS03000	COG2226	methyltransferase
ADS42_RS03055	COG2264	protein methyltransferase activity
ADS42_RS03060	COG0697	spore germination
ADS42_RS03065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADS42_RS03070	COG1674	ftsk spoiiie
ADS42_RS03075	COG0004	ammonium transporteR
ADS42_RS03080	COG1946	Acyl-CoA thioesterase
ADS42_RS03085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADS42_RS03200	COG1280	lysine exporter protein (LysE YggA)
ADS42_RS03210	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADS42_RS03220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADS42_RS03240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ADS42_RS03260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADS42_RS03265	COG0552	protein localization to endoplasmic reticulum
ADS42_RS03290	COG0494	nUDIX hydrolase
ADS42_RS03300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADS42_RS03305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADS42_RS03330	COG2194	sulfuric ester hydrolase activity
ADS42_RS03360	COG0765	amino acid transport
ADS42_RS03365	COG0765	amino acid transport
ADS42_RS03385	COG1126	abc transporter atp-binding protein
ADS42_RS03395	COG1802	Transcriptional regulator
ADS42_RS03425	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADS42_RS03435	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADS42_RS03440	COG2086	electron transfer activity
ADS42_RS03450	COG0720	synthase
ADS42_RS03455	COG0602	queuosine metabolic process
ADS42_RS03470	COG0300	oxidoreductase activity
ADS42_RS03485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADS42_RS03520	COG2226	methyltransferase
ADS42_RS03525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADS42_RS03530	COG0287	Prephenate dehydrogenase
ADS42_RS03560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ADS42_RS03580	COG2884	Cell division ATP-binding protein ftsE
ADS42_RS03595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADS42_RS03600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ADS42_RS03665	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADS42_RS03680	COG0789	Transcriptional regulator
ADS42_RS03685	COG2217	Heavy metal translocating P-type atpase
ADS42_RS03730	COG4536	flavin adenine dinucleotide binding
ADS42_RS03750	COG4974	Belongs to the 'phage' integrase family
ADS42_RS03770	COG0523	cobalamin synthesis protein
ADS42_RS03775	COG1686	Belongs to the peptidase S11 family
ADS42_RS03790	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS03820	COG1012	belongs to the aldehyde dehydrogenase family
ADS42_RS03825	COG1024	Enoyl-CoA hydratase
ADS42_RS03850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADS42_RS03870	COG4120	Belongs to the binding-protein-dependent transport system permease family
ADS42_RS03875	COG1122	ATPase activity
ADS42_RS03905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADS42_RS03915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADS42_RS03920	COG1981	membrane
ADS42_RS03940	COG0424	maF-like protein
ADS42_RS03970	COG4395	Tim44
ADS42_RS03980	COG2840	Smr protein MutS2
ADS42_RS03985	COG1396	sequence-specific DNA binding
ADS42_RS04015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADS42_RS04050	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ADS42_RS04055	COG0745	RESPONSE REGULATOR receiver
ADS42_RS04060	COG2205	protein histidine kinase activity
ADS42_RS04075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADS42_RS04075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADS42_RS04080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADS42_RS04100	COG2205	protein histidine kinase activity
ADS42_RS04105	COG3178	'Phosphotransferase
ADS42_RS04115	COG2887	Belongs to the helicase family. UvrD subfamily
ADS42_RS04120	COG1074	ATP-dependent DNA helicase activity
ADS42_RS04135	COG0285	dihydrofolate synthase activity
ADS42_RS04165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ADS42_RS04185	COG3135	benzoate transporter
ADS42_RS04195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADS42_RS04250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADS42_RS04265	COG3386	PFAM SMP-30 Gluconolaconase
ADS42_RS04270	COG0189	ligase activity
ADS42_RS04275	COG0606	chelatase, subunit chli
ADS42_RS04285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADS42_RS04295	COG2832	Protein of unknown function (DUF454)
ADS42_RS04300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADS42_RS04305	COG0573	inorganic phosphate transmembrane transporter activity
ADS42_RS04315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADS42_RS04320	COG0704	Plays a role in the regulation of phosphate uptake
ADS42_RS04325	COG0745	RESPONSE REGULATOR receiver
ADS42_RS04330	COG3773	Cell wall hydrolase
ADS42_RS04340	COG2309	aminopeptidase activity
ADS42_RS04345	COG0783	Belongs to the Dps family
ADS42_RS04355	COG0456	acetyltransferase
ADS42_RS04365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADS42_RS04385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ADS42_RS04390	COG1396	sequence-specific DNA binding
ADS42_RS04395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADS42_RS04400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADS42_RS04410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADS42_RS04410	COG0195	Participates in both transcription termination and antitermination
ADS42_RS04430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADS42_RS04450	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADS42_RS04490	COG0791	NLP P60 protein
ADS42_RS04500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADS42_RS04515	COG1024	Enoyl-CoA hydratase
ADS42_RS04550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADS42_RS04555	COG4172	Belongs to the ABC transporter superfamily
ADS42_RS04560	COG4239	(ABC) transporter, permease
ADS42_RS04565	COG4174	ABC transporter (Permease)
ADS42_RS04575	COG4166	transmembrane transport
ADS42_RS04595	COG0683	leucine binding
ADS42_RS04625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADS42_RS04630	COG1960	acyl-CoA dehydrogenase activity
ADS42_RS04675	COG0539	negative regulation of cytoplasmic translation
ADS42_RS04685	COG0583	DNA-binding transcription factor activity
ADS42_RS04695	COG2951	lytic endotransglycosylase activity
ADS42_RS04710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADS42_RS04725	COG2816	NAD+ diphosphatase activity
ADS42_RS04730	COG0077	Prephenate dehydratase
ADS42_RS04730	COG1605	Chorismate mutase
ADS42_RS04740	COG3474	cytochrome
ADS42_RS04750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ADS42_RS04755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADS42_RS04760	COG1845	cytochrome c oxidase, subunit III
ADS42_RS04765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADS42_RS04820	COG0346	lactoylglutathione lyase activity
ADS42_RS04825	COG0489	protein tyrosine kinase activity
ADS42_RS04830	COG0033	Phosphoglucomutase
ADS42_RS04845	COG1073	alpha beta
ADS42_RS04850	COG1072	(Pantothenic acid kinase))
ADS42_RS04880	COG1272	protein, Hemolysin III
ADS42_RS04885	COG0587	DNA-directed DNA polymerase activity
ADS42_RS04945	COG3339	Conserved Protein
ADS42_RS04955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADS42_RS04960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADS42_RS04975	COG4181	ATPase activity
ADS42_RS04985	COG0670	Belongs to the BI1 family
ADS42_RS05005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADS42_RS05015	COG4133	protoheme IX ABC transporter activity
ADS42_RS05020	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADS42_RS05025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADS42_RS05035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADS42_RS05080	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ADS42_RS05090	COG4208	sulfate ABC transporter
ADS42_RS05095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADS42_RS05100	COG3459	Glycosyltransferase 36 associated
ADS42_RS05110	COG0384	phenazine biosynthesis protein PhzF
ADS42_RS05115	COG2226	methyltransferase
ADS42_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS05130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADS42_RS05145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADS42_RS05150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADS42_RS05160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADS42_RS05160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADS42_RS05205	COG1643	Atp-dependent helicase
ADS42_RS05215	COG3293	Transposase
ADS42_RS05235	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ADS42_RS05245	COG1388	LysM domain
ADS42_RS05245	COG1376	ErfK ybiS ycfS ynhG family protein
ADS42_RS05250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ADS42_RS05260	COG0180	Tryptophanyl-tRNA synthetase
ADS42_RS05275	COG0280	phosphate acetyltransferase
ADS42_RS05275	COG0281	malic enzyme
ADS42_RS05280	COG0280	phosphate acetyltransferase
ADS42_RS05280	COG0281	malic enzyme
ADS42_RS05300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADS42_RS05325	COG0616	signal peptide processing
ADS42_RS05335	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ADS42_RS05340	COG1137	ATPase activity
ADS42_RS05345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADS42_RS05355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADS42_RS05360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADS42_RS05370	COG0071	Belongs to the small heat shock protein (HSP20) family
ADS42_RS05400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADS42_RS05405	COG2860	membrane
ADS42_RS05435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADS42_RS05440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADS42_RS05445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADS42_RS05455	COG1648	precorrin-2 dehydrogenase activity
ADS42_RS05455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADS42_RS05465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADS42_RS05470	COG0175	sulfate reduction
ADS42_RS05485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADS42_RS05510	COG2197	response regulator
ADS42_RS05515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADS42_RS05535	COG1218	3'(2'),5'-bisphosphate nucleotidase
ADS42_RS05550	COG2197	response regulator
ADS42_RS05575	COG1012	belongs to the aldehyde dehydrogenase family
ADS42_RS05605	COG1012	belongs to the aldehyde dehydrogenase family
ADS42_RS05615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ADS42_RS05620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADS42_RS05645	COG0351	phosphomethylpyrimidine kinase
ADS42_RS05650	COG5001	Diguanylate cyclase
ADS42_RS05665	COG1174	glycine betaine transport
ADS42_RS05670	COG1125	glycine betaine transport
ADS42_RS05675	COG1174	glycine betaine transport
ADS42_RS05680	COG1732	Glycine betaine
ADS42_RS05690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADS42_RS05705	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADS42_RS05705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADS42_RS05720	COG1414	Transcriptional regulator
ADS42_RS05730	COG1175	transmembrane transport
ADS42_RS05735	COG0395	ABC-type sugar transport system, permease component
ADS42_RS05740	COG3842	ATPase activity
ADS42_RS05745	COG4948	Mandelate Racemase Muconate Lactonizing
ADS42_RS05750	COG3254	rhamnose metabolic process
ADS42_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS05770	COG4948	Mandelate Racemase Muconate Lactonizing
ADS42_RS05795	COG0582	viral genome integration into host DNA
ADS42_RS05955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ADS42_RS05970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADS42_RS05980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADS42_RS06010	COG3617	BRO family, N-terminal domain
ADS42_RS06025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADS42_RS06065	COG0829	nickel cation binding
ADS42_RS06080	COG0804	urea catabolic process
ADS42_RS06090	COG0830	nickel cation binding
ADS42_RS06105	COG4191	Histidine kinase
ADS42_RS06115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADS42_RS06120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADS42_RS06140	COG1309	transcriptional regulator
ADS42_RS06145	COG0494	nUDIX hydrolase
ADS42_RS06155	COG0493	'glutamate synthase
ADS42_RS06185	COG0318	PFAM AMP-dependent synthetase and ligase
ADS42_RS06220	COG2326	polyphosphate kinase activity
ADS42_RS06225	COG5002	protein histidine kinase activity
ADS42_RS06240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADS42_RS06250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ADS42_RS06265	COG0717	Belongs to the dCTP deaminase family
ADS42_RS06285	COG0534	Mate efflux family protein
ADS42_RS06315	COG2205	protein histidine kinase activity
ADS42_RS06315	COG2198	Histidine kinase
ADS42_RS06315	COG0784	Response regulator, receiver
ADS42_RS06325	COG0156	8-amino-7-oxononanoate synthase activity
ADS42_RS06355	COG0583	DNA-binding transcription factor activity
ADS42_RS06360	COG1380	Effector of murein hydrolase LrgA
ADS42_RS06365	COG1346	cytolysis
ADS42_RS06405	COG0019	diaminopimelate decarboxylase activity
ADS42_RS06430	COG5342	invasion associated locus B
ADS42_RS06450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADS42_RS06455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADS42_RS06460	COG3257	ureidoglycine aminohydrolase activity
ADS42_RS06465	COG3195	allantoin biosynthetic process
ADS42_RS06465	COG3648	Uricase
ADS42_RS06475	COG2080	2 iron, 2 sulfur cluster binding
ADS42_RS06480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ADS42_RS06490	COG0583	DNA-binding transcription factor activity
ADS42_RS06500	COG0402	S-adenosylhomocysteine deaminase activity
ADS42_RS06560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADS42_RS06560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADS42_RS06570	COG2169	Transcriptional regulator
ADS42_RS06570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADS42_RS06575	COG1393	Belongs to the ArsC family
ADS42_RS06585	COG0477	Major facilitator Superfamily
ADS42_RS06590	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ADS42_RS06615	COG3773	Cell wall hydrolase
ADS42_RS06635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADS42_RS06675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADS42_RS06690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADS42_RS06690	COG0616	signal peptide processing
ADS42_RS06710	COG0142	geranyltranstransferase activity
ADS42_RS06725	COG0751	glycine-tRNA ligase activity
ADS42_RS06730	COG0009	L-threonylcarbamoyladenylate synthase
ADS42_RS06765	COG1960	acyl-CoA dehydrogenase activity
ADS42_RS06780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ADS42_RS06795	COG0484	heat shock protein binding
ADS42_RS06800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADS42_RS06815	COG1278	Cold shock
ADS42_RS06840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADS42_RS06840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADS42_RS06845	COG0123	including yeast histone deacetylase and acetoin utilization protein
ADS42_RS06850	COG1722	exodeoxyribonuclease VII activity
ADS42_RS06870	COG1741	Belongs to the pirin family
ADS42_RS06880	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ADS42_RS06885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADS42_RS06905	COG5265	(ABC) transporter
ADS42_RS06915	COG1183	phosphatidylcholine synthase activity
ADS42_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS06925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADS42_RS06945	COG0305	Participates in initiation and elongation during chromosome replication
ADS42_RS06950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ADS42_RS06980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ADS42_RS07005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADS42_RS07015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADS42_RS07025	COG1561	YicC-like family, N-terminal region
ADS42_RS07030	COG0194	GDP metabolic process
ADS42_RS07035	COG0312	modulator of DNA gyrase
ADS42_RS07045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ADS42_RS07050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADS42_RS07085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADS42_RS07100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADS42_RS07100	COG0678	peroxiredoxin activity
ADS42_RS07120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADS42_RS07125	COG0612	Peptidase, M16
ADS42_RS07140	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ADS42_RS07150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADS42_RS07160	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ADS42_RS07170	COG1194	a g-specific adenine glycosylase
ADS42_RS07190	COG1196	nuclear chromosome segregation
ADS42_RS07205	COG0574	Belongs to the PEP-utilizing enzyme family
ADS42_RS07205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADS42_RS07230	COG1268	BioY protein
ADS42_RS07240	COG2351	hydroxyisourate hydrolase activity
ADS42_RS07255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADS42_RS07315	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ADS42_RS07330	COG3293	Transposase
ADS42_RS07355	COG2801	Transposase and inactivated derivatives
ADS42_RS07360	COG2801	Transposase and inactivated derivatives
ADS42_RS07385	COG0662	Cupin 2, conserved barrel domain protein
ADS42_RS07385	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ADS42_RS07390	COG2942	2-epimerase
ADS42_RS07395	COG0438	transferase activity, transferring glycosyl groups
ADS42_RS07395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADS42_RS07415	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADS42_RS07420	COG1879	ABC-type sugar transport system periplasmic component
ADS42_RS07430	COG0673	inositol 2-dehydrogenase activity
ADS42_RS07440	COG1070	Carbohydrate kinase
ADS42_RS07465	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ADS42_RS07485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADS42_RS07505	COG2186	Transcriptional regulator
ADS42_RS07510	COG2807	transmembrane transport
ADS42_RS07520	COG0433	COG0433 Predicted ATPase
ADS42_RS07525	COG1376	ErfK ybiS ycfS ynhG family protein
ADS42_RS07540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADS42_RS07555	COG4957	zinc ion binding
ADS42_RS07565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADS42_RS07575	COG0154	amidase activity
ADS42_RS07580	COG2166	iron-sulfur cluster assembly
ADS42_RS07590	COG2205	protein histidine kinase activity
ADS42_RS07620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADS42_RS07635	COG4695	Portal protein
ADS42_RS07735	COG4235	cytochrome complex assembly
ADS42_RS07745	COG1138	Cytochrome C-type biogenesis protein
ADS42_RS07750	COG3088	subunit of a heme lyase
ADS42_RS07755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADS42_RS07760	COG0745	RESPONSE REGULATOR receiver
ADS42_RS07770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ADS42_RS07780	COG2202	Pas domain
ADS42_RS07780	COG2205	protein histidine kinase activity
ADS42_RS07785	COG0308	aminopeptidase N
ADS42_RS07800	COG1573	uracil-dna glycosylase
ADS42_RS07815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADS42_RS07820	COG0625	glutathione transferase activity
ADS42_RS07855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADS42_RS07860	COG4974	Belongs to the 'phage' integrase family
ADS42_RS07865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADS42_RS07890	COG3743	rRNA binding
ADS42_RS07890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADS42_RS07895	COG0741	lytic transglycosylase activity
ADS42_RS07935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADS42_RS07940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADS42_RS07945	COG2223	nitrite transmembrane transporter activity
ADS42_RS07950	COG2207	Transcriptional regulator
ADS42_RS07965	COG0681	Belongs to the peptidase S26 family
ADS42_RS07990	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ADS42_RS08000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ADS42_RS08020	COG0494	nUDIX hydrolase
ADS42_RS08050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADS42_RS08060	COG0739	heme binding
ADS42_RS08070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADS42_RS08075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADS42_RS08080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADS42_RS08115	COG0488	(ABC) transporter
ADS42_RS08135	COG0314	molybdopterin synthase activity
ADS42_RS08140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ADS42_RS08145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADS42_RS08160	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ADS42_RS08180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ADS42_RS08190	COG0243	molybdopterin cofactor binding
ADS42_RS08200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADS42_RS08215	COG0628	permease
ADS42_RS08240	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS08245	COG1620	l-lactate permease
ADS42_RS08250	COG1620	l-lactate permease
ADS42_RS08255	COG1620	l-lactate permease
ADS42_RS08285	COG3293	Transposase
ADS42_RS08380	COG0626	cystathionine gamma-synthase activity
ADS42_RS08390	COG0671	phosphoesterase, PA-phosphatase related
ADS42_RS08395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADS42_RS08405	COG4597	amino acid ABC transporter
ADS42_RS08415	COG1126	abc transporter atp-binding protein
ADS42_RS08430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ADS42_RS08440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ADS42_RS08460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADS42_RS08475	COG0113	porphobilinogen synthase activity
ADS42_RS08495	COG2989	Protein conserved in bacteria
ADS42_RS08510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADS42_RS08510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADS42_RS08530	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ADS42_RS08535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADS42_RS08625	COG0010	Belongs to the arginase family
ADS42_RS08665	COG3293	Transposase
ADS42_RS08715	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADS42_RS08735	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ADS42_RS08740	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ADS42_RS08780	COG1007	ATP synthesis coupled electron transport
ADS42_RS08795	COG0346	lactoylglutathione lyase activity
ADS42_RS08855	COG0483	inositol monophosphate 1-phosphatase activity
ADS42_RS08860	COG2814	Major facilitator Superfamily
ADS42_RS08900	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADS42_RS08930	COG2514	catechol 2,3-dioxygenase activity
ADS42_RS08935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADS42_RS08955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADS42_RS08960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADS42_RS08965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADS42_RS08985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADS42_RS08990	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ADS42_RS08995	COG3454	Phosphonate metabolism
ADS42_RS09000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADS42_RS09010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADS42_RS09035	COG1522	sequence-specific DNA binding
ADS42_RS09040	COG1573	uracil-dna glycosylase
ADS42_RS09070	COG0316	Belongs to the HesB IscA family
ADS42_RS09090	COG1472	Belongs to the glycosyl hydrolase 3 family
ADS42_RS09095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ADS42_RS09100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADS42_RS09110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADS42_RS09115	COG0805	protein transport
ADS42_RS09130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADS42_RS09150	COG1862	Preprotein translocase
ADS42_RS09200	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADS42_RS09220	COG4765	Protein conserved in bacteria
ADS42_RS09230	COG0439	Biotin carboxylase
ADS42_RS09235	COG0511	ligase activity, forming carbon-carbon bonds
ADS42_RS09250	COG0501	Belongs to the peptidase M48B family
ADS42_RS09255	COG0436	Aminotransferase
ADS42_RS09260	COG1530	ribonuclease E activity
ADS42_RS09270	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADS42_RS09275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADS42_RS09290	COG3293	Transposase
ADS42_RS09305	COG2833	Protein of unknown function (DUF455)
ADS42_RS09310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADS42_RS09325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ADS42_RS09335	COG2945	thiolester hydrolase activity
ADS42_RS09345	COG0719	Fe-S assembly protein
ADS42_RS09350	COG0396	ATPase activity
ADS42_RS09355	COG0719	Fe-S assembly protein
ADS42_RS09360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADS42_RS09365	COG2151	metal-sulfur cluster biosynthetic enzyme
ADS42_RS09380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADS42_RS09385	COG0513	Belongs to the DEAD box helicase family
ADS42_RS09390	COG0316	Belongs to the HesB IscA family
ADS42_RS09410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADS42_RS09430	COG0525	valine-tRNA ligase activity
ADS42_RS09445	COG2084	Dehydrogenase
ADS42_RS09450	COG0625	glutathione transferase activity
ADS42_RS09500	COG2989	Protein conserved in bacteria
ADS42_RS09595	COG3293	Transposase
ADS42_RS09640	COG1393	Belongs to the ArsC family
ADS42_RS09670	COG0084	hydrolase, TatD family'
ADS42_RS09680	COG1132	(ABC) transporter
ADS42_RS09705	COG0174	glutamine synthetase
ADS42_RS09710	COG0347	Belongs to the P(II) protein family
ADS42_RS09715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADS42_RS09715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADS42_RS09725	COG0546	phosphoglycolate phosphatase activity
ADS42_RS09730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ADS42_RS09745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ADS42_RS09750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADS42_RS09760	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ADS42_RS09760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADS42_RS09770	COG0280	phosphate acetyltransferase
ADS42_RS09770	COG0281	malic enzyme
ADS42_RS09780	COG4948	Mandelate Racemase Muconate Lactonizing
ADS42_RS09785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADS42_RS09795	COG1127	ABC transporter
ADS42_RS09820	COG0633	Ferredoxin
ADS42_RS09825	COG0492	ferredoxin-NADP+ reductase activity
ADS42_RS09840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADS42_RS09850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADS42_RS09890	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ADS42_RS09900	COG0668	transmembrane transport
ADS42_RS09905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADS42_RS09940	COG1546	Belongs to the CinA family
ADS42_RS09940	COG1058	Belongs to the CinA family
ADS42_RS09960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADS42_RS09965	COG0513	Belongs to the DEAD box helicase family
ADS42_RS09970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADS42_RS09975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADS42_RS09980	COG2897	thiosulfate sulfurtransferase activity
ADS42_RS09995	COG0427	acetyl-CoA hydrolase
ADS42_RS10000	COG2814	Major facilitator Superfamily
ADS42_RS10005	COG1566	PFAM secretion protein HlyD family protein
ADS42_RS10015	COG0006	proline dipeptidase activity
ADS42_RS10020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADS42_RS10035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADS42_RS10045	COG3956	TIGRFAM MazG family protein
ADS42_RS10050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADS42_RS10100	COG1752	Esterase of the alpha-beta hydrolase superfamily
ADS42_RS10155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADS42_RS10170	COG3617	BRO family, N-terminal domain
ADS42_RS10180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADS42_RS10185	COG1960	acyl-CoA dehydrogenase activity
ADS42_RS10195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADS42_RS10200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADS42_RS10205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADS42_RS10240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADS42_RS10245	COG2095	MarC family integral membrane protein
ADS42_RS10255	COG2188	Transcriptional regulator
ADS42_RS10285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADS42_RS10295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADS42_RS10310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADS42_RS10330	COG0569	domain protein
ADS42_RS10335	COG2204	response regulator
ADS42_RS10340	COG5000	phosphorelay sensor kinase activity
ADS42_RS10345	COG2204	response regulator
ADS42_RS10350	COG3852	Histidine kinase
ADS42_RS10365	COG1058	Belongs to the CinA family
ADS42_RS10365	COG1546	Belongs to the CinA family
ADS42_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
ADS42_RS10375	COG2867	negative regulation of translational initiation
ADS42_RS10390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADS42_RS10395	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADS42_RS10400	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADS42_RS10400	COG0022	dehydrogenase e1 component
ADS42_RS10405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ADS42_RS10410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ADS42_RS10455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADS42_RS10475	COG0303	'Molybdopterin
ADS42_RS10485	COG0658	competence protein
ADS42_RS10485	COG2333	competence protein COMEC
ADS42_RS10495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADS42_RS10500	COG0372	Belongs to the citrate synthase family
ADS42_RS10505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADS42_RS10530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADS42_RS10535	COG0750	zinc metalloprotease
ADS42_RS10555	COG0528	UMP kinase activity
ADS42_RS10585	COG0584	glycerophosphoryl diester phosphodiesterase
ADS42_RS10595	COG0537	adenosine 5'-monophosphoramidase activity
ADS42_RS10615	COG1686	Belongs to the peptidase S11 family
ADS42_RS10630	COG1760	l-serine dehydratase
ADS42_RS10675	COG3800	Transcriptional regulator
ADS42_RS10675	COG1396	sequence-specific DNA binding
ADS42_RS10680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADS42_RS10685	COG4770	biotin carboxylase activity
ADS42_RS10690	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADS42_RS10690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADS42_RS10705	COG2358	TRAP transporter, solute receptor (TAXI family
ADS42_RS10715	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ADS42_RS10720	COG0693	protein deglycase activity
ADS42_RS10730	COG0538	isocitrate dehydrogenase activity
ADS42_RS10735	COG1785	Belongs to the alkaline phosphatase family
ADS42_RS10750	COG2885	chlorophyll binding
ADS42_RS10760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADS42_RS10765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADS42_RS10815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADS42_RS10880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADS42_RS10970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADS42_RS11000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADS42_RS11005	COG0516	GMP reductase activity
ADS42_RS11005	COG0517	IMP dehydrogenase activity
ADS42_RS11060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADS42_RS11370	COG4208	sulfate ABC transporter
ADS42_RS12215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADS42_RS12260	COG0556	nucleotide-excision repair
ADS42_RS12515	COG0512	Glutamine amidotransferase of anthranilate synthase
ADS42_RS12515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADS42_RS12570	COG3448	diguanylate cyclase activity
ADS42_RS12570	COG4175	Glycine betaine
ADS42_RS13435	COG0142	geranyltranstransferase activity
ADS42_RS13690	COG2902	Dehydrogenase
ADS42_RS14015	COG0697	spore germination
ADS42_RS14060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADS42_RS14315	COG0114	fumarate hydratase activity
ADS42_RS14725	COG1024	Enoyl-CoA hydratase
ADS42_RS15265	COG1702	phosphate starvation-inducible protein PhoH
ADS42_RS15905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADS42_RS15990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADS42_RS16000	COG3459	Glycosyltransferase 36 associated
ADS42_RS16015	COG3459	Glycosyltransferase 36 associated
ADS42_RS16120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADS42_RS16120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADS42_RS16130	COG0513	Belongs to the DEAD box helicase family
ADS42_RS16240	COG0728	peptidoglycan biosynthetic process
ADS42_RS16505	COG1012	belongs to the aldehyde dehydrogenase family