locus-tag	class	description
F9L69_RS00005	COG0628	permease
F9L69_RS00030	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS00150	COG0626	cystathionine gamma-synthase activity
F9L69_RS00160	COG0671	phosphoesterase, PA-phosphatase related
F9L69_RS00165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9L69_RS00175	COG4597	amino acid ABC transporter
F9L69_RS00185	COG1126	abc transporter atp-binding protein
F9L69_RS00200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F9L69_RS00210	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F9L69_RS00230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F9L69_RS00245	COG0113	porphobilinogen synthase activity
F9L69_RS00265	COG2989	Protein conserved in bacteria
F9L69_RS00280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9L69_RS00280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9L69_RS00300	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F9L69_RS00305	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9L69_RS00395	COG0010	Belongs to the arginase family
F9L69_RS00480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9L69_RS00500	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F9L69_RS00505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F9L69_RS00545	COG1007	ATP synthesis coupled electron transport
F9L69_RS00560	COG0346	lactoylglutathione lyase activity
F9L69_RS00620	COG0483	inositol monophosphate 1-phosphatase activity
F9L69_RS00625	COG2814	Major facilitator Superfamily
F9L69_RS00665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F9L69_RS00700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9L69_RS00720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F9L69_RS00725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F9L69_RS00730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F9L69_RS00750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9L69_RS00755	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F9L69_RS00760	COG3454	Phosphonate metabolism
F9L69_RS00765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9L69_RS00770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9L69_RS00775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9L69_RS00800	COG1522	sequence-specific DNA binding
F9L69_RS00805	COG1573	uracil-dna glycosylase
F9L69_RS00835	COG0316	Belongs to the HesB IscA family
F9L69_RS00855	COG1472	Belongs to the glycosyl hydrolase 3 family
F9L69_RS00860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F9L69_RS00865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F9L69_RS00875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F9L69_RS00880	COG0805	protein transport
F9L69_RS00895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F9L69_RS00915	COG1862	Preprotein translocase
F9L69_RS00965	COG0544	peptidyl-prolyl cis-trans isomerase activity
F9L69_RS00985	COG4765	Protein conserved in bacteria
F9L69_RS00995	COG0439	Biotin carboxylase
F9L69_RS01000	COG0511	ligase activity, forming carbon-carbon bonds
F9L69_RS01015	COG0501	Belongs to the peptidase M48B family
F9L69_RS01025	COG0436	Aminotransferase
F9L69_RS01030	COG1530	ribonuclease E activity
F9L69_RS01040	COG0860	N-Acetylmuramoyl-L-alanine amidase
F9L69_RS01045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F9L69_RS01070	COG2833	Protein of unknown function (DUF455)
F9L69_RS01075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9L69_RS01090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F9L69_RS01100	COG2945	thiolester hydrolase activity
F9L69_RS01115	COG0396	ATPase activity
F9L69_RS01120	COG0719	Fe-S assembly protein
F9L69_RS01125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F9L69_RS01130	COG2151	metal-sulfur cluster biosynthetic enzyme
F9L69_RS01145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F9L69_RS01150	COG0513	Belongs to the DEAD box helicase family
F9L69_RS01155	COG0316	Belongs to the HesB IscA family
F9L69_RS01175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F9L69_RS01195	COG0525	valine-tRNA ligase activity
F9L69_RS01210	COG2084	Dehydrogenase
F9L69_RS01265	COG2989	Protein conserved in bacteria
F9L69_RS01400	COG1393	Belongs to the ArsC family
F9L69_RS01430	COG0084	hydrolase, TatD family'
F9L69_RS01440	COG1132	(ABC) transporter
F9L69_RS01465	COG0174	glutamine synthetase
F9L69_RS01470	COG0347	Belongs to the P(II) protein family
F9L69_RS01475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9L69_RS01475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9L69_RS01485	COG0546	phosphoglycolate phosphatase activity
F9L69_RS01490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F9L69_RS01505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F9L69_RS01510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F9L69_RS01520	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
F9L69_RS01520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9L69_RS01530	COG0281	malic enzyme
F9L69_RS01530	COG0280	phosphate acetyltransferase
F9L69_RS01540	COG4948	Mandelate Racemase Muconate Lactonizing
F9L69_RS01545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9L69_RS01555	COG1127	ABC transporter
F9L69_RS01580	COG0633	Ferredoxin
F9L69_RS01585	COG0492	ferredoxin-NADP+ reductase activity
F9L69_RS01600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9L69_RS01610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9L69_RS01625	COG3106	COG3106 Predicted ATPase
F9L69_RS01650	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
F9L69_RS01660	COG0668	transmembrane transport
F9L69_RS01665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9L69_RS01705	COG1546	Belongs to the CinA family
F9L69_RS01705	COG1058	Belongs to the CinA family
F9L69_RS01735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9L69_RS01740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F9L69_RS01745	COG2897	thiosulfate sulfurtransferase activity
F9L69_RS01765	COG0427	acetyl-CoA hydrolase
F9L69_RS01770	COG2814	Major facilitator Superfamily
F9L69_RS01775	COG1566	PFAM secretion protein HlyD family protein
F9L69_RS01785	COG0006	proline dipeptidase activity
F9L69_RS01790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9L69_RS01805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9L69_RS01815	COG3956	TIGRFAM MazG family protein
F9L69_RS01865	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9L69_RS01920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F9L69_RS01935	COG3617	BRO family, N-terminal domain
F9L69_RS01945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9L69_RS01950	COG1960	acyl-CoA dehydrogenase activity
F9L69_RS01955	COG0583	DNA-binding transcription factor activity
F9L69_RS01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9L69_RS01965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9L69_RS01970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9L69_RS02010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F9L69_RS02015	COG2095	MarC family integral membrane protein
F9L69_RS02025	COG2188	Transcriptional regulator
F9L69_RS02055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F9L69_RS02065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F9L69_RS02080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9L69_RS02100	COG0569	domain protein
F9L69_RS02110	COG5000	phosphorelay sensor kinase activity
F9L69_RS02115	COG2204	response regulator
F9L69_RS02120	COG3852	Histidine kinase
F9L69_RS02135	COG1058	Belongs to the CinA family
F9L69_RS02135	COG1546	Belongs to the CinA family
F9L69_RS02145	COG2867	negative regulation of translational initiation
F9L69_RS02160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9L69_RS02165	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9L69_RS02170	COG0022	dehydrogenase e1 component
F9L69_RS02170	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9L69_RS02175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9L69_RS02180	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F9L69_RS02225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9L69_RS02245	COG0303	'Molybdopterin
F9L69_RS02255	COG0658	competence protein
F9L69_RS02255	COG2333	competence protein COMEC
F9L69_RS02265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9L69_RS02270	COG0372	Belongs to the citrate synthase family
F9L69_RS02275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9L69_RS02300	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9L69_RS02305	COG0750	zinc metalloprotease
F9L69_RS02325	COG0528	UMP kinase activity
F9L69_RS02355	COG0584	glycerophosphoryl diester phosphodiesterase
F9L69_RS02365	COG0537	adenosine 5'-monophosphoramidase activity
F9L69_RS02400	COG1760	l-serine dehydratase
F9L69_RS02445	COG3800	Transcriptional regulator
F9L69_RS02445	COG1396	sequence-specific DNA binding
F9L69_RS02450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9L69_RS02455	COG4770	biotin carboxylase activity
F9L69_RS02460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9L69_RS02460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9L69_RS02475	COG2358	TRAP transporter, solute receptor (TAXI family
F9L69_RS02485	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F9L69_RS02490	COG0693	protein deglycase activity
F9L69_RS02500	COG0538	isocitrate dehydrogenase activity
F9L69_RS02505	COG1785	Belongs to the alkaline phosphatase family
F9L69_RS02520	COG2885	chlorophyll binding
F9L69_RS02530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9L69_RS02535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9L69_RS02650	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F9L69_RS02740	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F9L69_RS02770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9L69_RS02775	COG0517	IMP dehydrogenase activity
F9L69_RS02775	COG0516	GMP reductase activity
F9L69_RS02830	COG0346	lactoylglutathione lyase activity
F9L69_RS02845	COG1181	Belongs to the D-alanine--D-alanine ligase family
F9L69_RS02850	COG1494	fructose-1,6-bisphosphatase
F9L69_RS02860	COG0436	Aminotransferase
F9L69_RS02895	COG0024	Methionine aminopeptidase
F9L69_RS02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9L69_RS02960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
F9L69_RS03065	COG0583	DNA-binding transcription factor activity
F9L69_RS03090	COG3264	Mechanosensitive ion channel
F9L69_RS03090	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F9L69_RS03105	COG4651	solute:proton antiporter activity
F9L69_RS03105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9L69_RS03125	COG4208	sulfate ABC transporter
F9L69_RS03130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F9L69_RS03135	COG4150	thiosulfate binding
F9L69_RS03145	COG1253	flavin adenine dinucleotide binding
F9L69_RS03150	COG0586	Pfam SNARE associated Golgi protein
F9L69_RS03170	COG4154	Belongs to the RbsD FucU family
F9L69_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS03200	COG1120	ATPase activity
F9L69_RS03205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9L69_RS03220	COG0842	Transport permease protein
F9L69_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9L69_RS03245	COG1649	PFAM Uncharacterised BCR, COG1649
F9L69_RS03260	COG0804	urea catabolic process
F9L69_RS03285	COG4413	Urea transporter
F9L69_RS03295	COG0310	cobalt ion transport
F9L69_RS03315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F9L69_RS03315	COG3439	Domain of unknown function DUF302
F9L69_RS03335	COG0384	phenazine biosynthesis protein PhzF
F9L69_RS03360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9L69_RS03380	COG3158	transport of potassium into the cell
F9L69_RS03395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9L69_RS03400	COG0440	acetolactate synthase activity
F9L69_RS03405	COG0028	Belongs to the TPP enzyme family
F9L69_RS03440	COG0330	HflC and HflK could
F9L69_RS03475	COG2814	Major facilitator Superfamily
F9L69_RS03505	COG0277	FAD linked oxidase domain protein
F9L69_RS03520	COG0210	DNA helicase
F9L69_RS03535	COG1999	signal sequence binding
F9L69_RS03545	COG0006	proline dipeptidase activity
F9L69_RS03565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9L69_RS03580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F9L69_RS03585	COG0849	cell division
F9L69_RS03590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F9L69_RS03595	COG1181	Belongs to the D-alanine--D-alanine ligase family
F9L69_RS03635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9L69_RS03660	COG1914	H( )-stimulated, divalent metal cation uptake system
F9L69_RS03675	COG3023	N-Acetylmuramoyl-L-alanine amidase
F9L69_RS03680	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F9L69_RS03710	COG0640	Transcriptional regulator
F9L69_RS03720	COG0477	Major facilitator Superfamily
F9L69_RS03745	COG2267	carboxylic ester hydrolase activity
F9L69_RS03770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9L69_RS03775	COG2824	Alkylphosphonate utilization operon protein PhnA
F9L69_RS03780	COG1335	isochorismatase
F9L69_RS03805	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
F9L69_RS03850	COG2968	Membrane
F9L69_RS03870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F9L69_RS03880	COG0358	DNA primase activity
F9L69_RS03900	COG2321	neutral zinc metallopeptidase
F9L69_RS03915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F9L69_RS03925	COG1136	(ABC) transporter
F9L69_RS03935	COG1278	Cold shock
F9L69_RS03940	COG0625	glutathione transferase activity
F9L69_RS03945	COG0436	Aminotransferase
F9L69_RS03960	COG0583	DNA-binding transcription factor activity
F9L69_RS03965	COG0492	ferredoxin-NADP+ reductase activity
F9L69_RS03970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9L69_RS03975	COG1522	sequence-specific DNA binding
F9L69_RS04025	COG0556	nucleotide-excision repair
F9L69_RS04030	COG1196	nuclear chromosome segregation
F9L69_RS04030	COG0739	heme binding
F9L69_RS04030	COG0741	lytic transglycosylase activity
F9L69_RS04035	COG1278	Cold shock
F9L69_RS04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9L69_RS04065	COG1846	Transcriptional regulator
F9L69_RS04070	COG0745	RESPONSE REGULATOR receiver
F9L69_RS04075	COG2205	protein histidine kinase activity
F9L69_RS04080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9L69_RS04115	COG1496	oxidoreductase activity
F9L69_RS04135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9L69_RS04160	COG2030	dehydratase
F9L69_RS04175	COG2857	Cytochrome c1
F9L69_RS04175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F9L69_RS04190	COG1132	(ABC) transporter
F9L69_RS04195	COG1132	(ABC) transporter
F9L69_RS04200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F9L69_RS04220	COG3153	acetyltransferase
F9L69_RS04235	COG0617	tRNA 3'-terminal CCA addition
F9L69_RS04250	COG0714	Associated with various cellular activities
F9L69_RS04275	COG0435	Glutathione S-transferase
F9L69_RS04280	COG3047	cAMP biosynthetic process
F9L69_RS04285	COG1051	belongs to the nudix hydrolase family
F9L69_RS04295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9L69_RS04300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F9L69_RS04315	COG1522	sequence-specific DNA binding
F9L69_RS04345	COG4176	ABC-type proline glycine betaine transport system permease component
F9L69_RS04350	COG4175	Glycine betaine
F9L69_RS04355	COG4608	Belongs to the ABC transporter superfamily
F9L69_RS04360	COG0444	Belongs to the ABC transporter superfamily
F9L69_RS04365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9L69_RS04370	COG0601	transmembrane transport
F9L69_RS04480	COG2205	protein histidine kinase activity
F9L69_RS04500	COG1177	transmembrane transport
F9L69_RS04505	COG1176	ABC-type spermidine putrescine transport system, permease component I
F9L69_RS04510	COG3842	ATPase activity
F9L69_RS04530	COG2224	Isocitrate lyase
F9L69_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS04565	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9L69_RS04580	COG1461	Dihydroxyacetone kinase
F9L69_RS04585	COG2376	Dihydroxyacetone kinase
F9L69_RS04590	COG1461	Dihydroxyacetone kinase
F9L69_RS04595	COG2376	Dihydroxyacetone kinase
F9L69_RS04605	COG1879	ABC-type sugar transport system periplasmic component
F9L69_RS04610	COG1172	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS04615	COG1129	ABC transporter
F9L69_RS04675	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS04700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9L69_RS04715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F9L69_RS04720	COG0564	pseudouridine synthase activity
F9L69_RS04735	COG0735	belongs to the Fur family
F9L69_RS04755	COG0784	Response regulator, receiver
F9L69_RS04775	COG3920	Histidine kinase
F9L69_RS04805	COG0848	biopolymer transport protein
F9L69_RS04825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9L69_RS04835	COG1522	sequence-specific DNA binding
F9L69_RS04855	COG0477	Major facilitator Superfamily
F9L69_RS04875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9L69_RS04885	COG0385	Bile acid
F9L69_RS04895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9L69_RS04900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9L69_RS04915	COG2885	chlorophyll binding
F9L69_RS04935	COG0848	biopolymer transport protein
F9L69_RS04945	COG0824	Thioesterase
F9L69_RS04990	COG0483	inositol monophosphate 1-phosphatase activity
F9L69_RS05005	COG1132	(ABC) transporter
F9L69_RS05035	COG1253	flavin adenine dinucleotide binding
F9L69_RS05040	COG1692	metallophosphoesterase
F9L69_RS05090	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS05115	COG3321	synthase
F9L69_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS05115	COG0604	alcohol dehydrogenase
F9L69_RS05145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F9L69_RS05150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9L69_RS05160	COG0457	Tetratricopeptide repeat
F9L69_RS05165	COG0469	pyruvate kinase activity
F9L69_RS05180	COG3750	Belongs to the UPF0335 family
F9L69_RS05185	COG0488	(ABC) transporter
F9L69_RS05205	COG4143	(ABC) transporter
F9L69_RS05210	COG1178	ABC-type Fe3 transport system permease component
F9L69_RS05225	COG2258	MOSC domain
F9L69_RS05230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F9L69_RS05245	COG1329	Transcriptional regulator
F9L69_RS05250	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F9L69_RS05290	COG0142	geranyltranstransferase activity
F9L69_RS05300	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS05305	COG0738	Major facilitator superfamily
F9L69_RS05310	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F9L69_RS05320	COG0683	leucine binding
F9L69_RS05350	COG3938	Belongs to the proline racemase family
F9L69_RS05425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F9L69_RS05435	COG5425	PFAM Usg family protein
F9L69_RS05455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9L69_RS05455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F9L69_RS05470	COG2270	Major facilitator Superfamily
F9L69_RS05485	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F9L69_RS05490	COG1704	LemA family
F9L69_RS05500	COG1605	Chorismate mutase
F9L69_RS05500	COG0287	Prephenate dehydrogenase
F9L69_RS05505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9L69_RS05520	COG0288	reversible hydration of carbon dioxide
F9L69_RS05580	COG0799	negative regulation of ribosome biogenesis
F9L69_RS05645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9L69_RS05700	COG0739	heme binding
F9L69_RS05710	COG0542	response to heat
F9L69_RS05725	COG2890	protein-(glutamine-N5) methyltransferase activity
F9L69_RS05740	COG0527	aspartate kinase activity
F9L69_RS05765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9L69_RS05770	COG1040	competence protein
F9L69_RS05775	COG2226	methyltransferase
F9L69_RS05830	COG2264	protein methyltransferase activity
F9L69_RS05835	COG0697	spore germination
F9L69_RS05840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9L69_RS05845	COG1674	ftsk spoiiie
F9L69_RS05850	COG0004	ammonium transporteR
F9L69_RS05855	COG1946	Acyl-CoA thioesterase
F9L69_RS05860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9L69_RS05975	COG1280	lysine exporter protein (LysE YggA)
F9L69_RS05985	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9L69_RS05995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F9L69_RS06015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F9L69_RS06035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9L69_RS06065	COG0494	nUDIX hydrolase
F9L69_RS06075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F9L69_RS06080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9L69_RS06110	COG2194	sulfuric ester hydrolase activity
F9L69_RS06140	COG0765	amino acid transport
F9L69_RS06145	COG0765	amino acid transport
F9L69_RS06165	COG1126	abc transporter atp-binding protein
F9L69_RS06175	COG1802	Transcriptional regulator
F9L69_RS06180	COG0252	asparaginase activity
F9L69_RS06205	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9L69_RS06215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F9L69_RS06220	COG2086	electron transfer activity
F9L69_RS06230	COG0720	synthase
F9L69_RS06235	COG0602	queuosine metabolic process
F9L69_RS06250	COG0300	oxidoreductase activity
F9L69_RS06265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9L69_RS06300	COG2226	methyltransferase
F9L69_RS06305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F9L69_RS06310	COG0287	Prephenate dehydrogenase
F9L69_RS06340	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9L69_RS06360	COG2884	Cell division ATP-binding protein ftsE
F9L69_RS06375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F9L69_RS06380	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F9L69_RS06445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F9L69_RS06460	COG0789	Transcriptional regulator
F9L69_RS06465	COG2217	Heavy metal translocating P-type atpase
F9L69_RS06510	COG4536	flavin adenine dinucleotide binding
F9L69_RS06530	COG4974	Belongs to the 'phage' integrase family
F9L69_RS06550	COG0523	cobalamin synthesis protein
F9L69_RS06555	COG1686	Belongs to the peptidase S11 family
F9L69_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS06600	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS06605	COG1024	Enoyl-CoA hydratase
F9L69_RS06630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9L69_RS06650	COG4120	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS06655	COG0410	ABC transporter
F9L69_RS06690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F9L69_RS06700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F9L69_RS06705	COG1981	membrane
F9L69_RS06725	COG0424	maF-like protein
F9L69_RS06735	COG0237	dephospho-CoA kinase activity
F9L69_RS06755	COG4395	Tim44
F9L69_RS06765	COG2840	Smr protein MutS2
F9L69_RS06770	COG1396	sequence-specific DNA binding
F9L69_RS06800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F9L69_RS06835	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F9L69_RS06840	COG0745	RESPONSE REGULATOR receiver
F9L69_RS06845	COG2205	protein histidine kinase activity
F9L69_RS06860	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9L69_RS06860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9L69_RS06865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9L69_RS06885	COG2205	protein histidine kinase activity
F9L69_RS06890	COG3178	'Phosphotransferase
F9L69_RS06895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F9L69_RS06900	COG2887	Belongs to the helicase family. UvrD subfamily
F9L69_RS06905	COG1074	ATP-dependent DNA helicase activity
F9L69_RS06920	COG0285	dihydrofolate synthase activity
F9L69_RS06950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F9L69_RS06970	COG3135	benzoate transporter
F9L69_RS06980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F9L69_RS07035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9L69_RS07050	COG3386	PFAM SMP-30 Gluconolaconase
F9L69_RS07055	COG0189	ligase activity
F9L69_RS07070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F9L69_RS07085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F9L69_RS07090	COG0573	inorganic phosphate transmembrane transporter activity
F9L69_RS07100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9L69_RS07105	COG0704	Plays a role in the regulation of phosphate uptake
F9L69_RS07110	COG0745	RESPONSE REGULATOR receiver
F9L69_RS07115	COG3773	Cell wall hydrolase
F9L69_RS07125	COG2309	aminopeptidase activity
F9L69_RS07130	COG0783	Belongs to the Dps family
F9L69_RS07140	COG0456	acetyltransferase
F9L69_RS07150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9L69_RS07170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F9L69_RS07175	COG1396	sequence-specific DNA binding
F9L69_RS07180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F9L69_RS07185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9L69_RS07195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F9L69_RS07195	COG0195	Participates in both transcription termination and antitermination
F9L69_RS07220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F9L69_RS07240	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F9L69_RS07280	COG0791	NLP P60 protein
F9L69_RS07290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F9L69_RS07305	COG1024	Enoyl-CoA hydratase
F9L69_RS07340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9L69_RS07345	COG4172	Belongs to the ABC transporter superfamily
F9L69_RS07350	COG4239	(ABC) transporter, permease
F9L69_RS07355	COG4174	ABC transporter (Permease)
F9L69_RS07365	COG4166	transmembrane transport
F9L69_RS07385	COG0683	leucine binding
F9L69_RS07410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9L69_RS07415	COG1960	acyl-CoA dehydrogenase activity
F9L69_RS07460	COG0539	negative regulation of cytoplasmic translation
F9L69_RS07465	COG2855	membrane
F9L69_RS07470	COG0583	DNA-binding transcription factor activity
F9L69_RS07480	COG2951	lytic endotransglycosylase activity
F9L69_RS07495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9L69_RS07510	COG2816	NAD+ diphosphatase activity
F9L69_RS07515	COG1605	Chorismate mutase
F9L69_RS07515	COG0077	Prephenate dehydratase
F9L69_RS07525	COG3474	cytochrome
F9L69_RS07535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9L69_RS07540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9L69_RS07545	COG1845	cytochrome c oxidase, subunit III
F9L69_RS07550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F9L69_RS07610	COG0346	lactoylglutathione lyase activity
F9L69_RS07620	COG0033	Phosphoglucomutase
F9L69_RS07635	COG1073	alpha beta
F9L69_RS07640	COG1072	(Pantothenic acid kinase))
F9L69_RS07670	COG1272	protein, Hemolysin III
F9L69_RS07675	COG0587	DNA-directed DNA polymerase activity
F9L69_RS07740	COG3339	Conserved Protein
F9L69_RS07750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F9L69_RS07755	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F9L69_RS07780	COG0670	Belongs to the BI1 family
F9L69_RS07800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F9L69_RS07810	COG4133	protoheme IX ABC transporter activity
F9L69_RS07815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F9L69_RS07820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F9L69_RS07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9L69_RS07875	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9L69_RS07885	COG4208	sulfate ABC transporter
F9L69_RS07890	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F9L69_RS07895	COG3459	Glycosyltransferase 36 associated
F9L69_RS07905	COG0384	phenazine biosynthesis protein PhzF
F9L69_RS07910	COG2226	methyltransferase
F9L69_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS07925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F9L69_RS07940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9L69_RS07945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F9L69_RS07955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9L69_RS07955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9L69_RS08000	COG1643	Atp-dependent helicase
F9L69_RS08025	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F9L69_RS08035	COG1376	ErfK ybiS ycfS ynhG family protein
F9L69_RS08035	COG1388	LysM domain
F9L69_RS08050	COG0180	Tryptophanyl-tRNA synthetase
F9L69_RS08055	COG0728	peptidoglycan biosynthetic process
F9L69_RS08065	COG0281	malic enzyme
F9L69_RS08065	COG0280	phosphate acetyltransferase
F9L69_RS08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9L69_RS08115	COG0616	signal peptide processing
F9L69_RS08125	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F9L69_RS08130	COG1137	ATPase activity
F9L69_RS08135	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F9L69_RS08145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F9L69_RS08150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9L69_RS08160	COG0071	Belongs to the small heat shock protein (HSP20) family
F9L69_RS08190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9L69_RS08195	COG2860	membrane
F9L69_RS08230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F9L69_RS08235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9L69_RS08240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F9L69_RS08250	COG1648	precorrin-2 dehydrogenase activity
F9L69_RS08250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9L69_RS08260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9L69_RS08265	COG0175	sulfate reduction
F9L69_RS08305	COG2197	response regulator
F9L69_RS08310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F9L69_RS08330	COG1218	3'(2'),5'-bisphosphate nucleotidase
F9L69_RS08345	COG2197	response regulator
F9L69_RS08370	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS08400	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS08410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9L69_RS08415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9L69_RS08440	COG0351	phosphomethylpyrimidine kinase
F9L69_RS08445	COG5001	Diguanylate cyclase
F9L69_RS08460	COG1174	glycine betaine transport
F9L69_RS08465	COG1125	glycine betaine transport
F9L69_RS08470	COG1174	glycine betaine transport
F9L69_RS08475	COG1732	Glycine betaine
F9L69_RS08485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9L69_RS08500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F9L69_RS08500	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9L69_RS08515	COG1414	Transcriptional regulator
F9L69_RS08530	COG0395	ABC-type sugar transport system, permease component
F9L69_RS08535	COG3842	ATPase activity
F9L69_RS08540	COG4948	Mandelate Racemase Muconate Lactonizing
F9L69_RS08545	COG3254	rhamnose metabolic process
F9L69_RS08555	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS08565	COG4948	Mandelate Racemase Muconate Lactonizing
F9L69_RS08590	COG0582	viral genome integration into host DNA
F9L69_RS08745	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F9L69_RS08760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F9L69_RS08770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9L69_RS08800	COG3617	BRO family, N-terminal domain
F9L69_RS08815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F9L69_RS08855	COG0829	nickel cation binding
F9L69_RS08870	COG0804	urea catabolic process
F9L69_RS08880	COG0830	nickel cation binding
F9L69_RS08895	COG4191	Histidine kinase
F9L69_RS08905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9L69_RS08910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9L69_RS08930	COG0494	nUDIX hydrolase
F9L69_RS08940	COG0493	'glutamate synthase
F9L69_RS08970	COG0318	PFAM AMP-dependent synthetase and ligase
F9L69_RS09010	COG2326	polyphosphate kinase activity
F9L69_RS09015	COG5002	protein histidine kinase activity
F9L69_RS09030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9L69_RS09040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F9L69_RS09060	COG0717	Belongs to the dCTP deaminase family
F9L69_RS09110	COG2198	Histidine kinase
F9L69_RS09110	COG2205	protein histidine kinase activity
F9L69_RS09110	COG0784	Response regulator, receiver
F9L69_RS09120	COG0156	8-amino-7-oxononanoate synthase activity
F9L69_RS09145	COG0583	DNA-binding transcription factor activity
F9L69_RS09150	COG1380	Effector of murein hydrolase LrgA
F9L69_RS09155	COG1346	cytolysis
F9L69_RS09195	COG0019	diaminopimelate decarboxylase activity
F9L69_RS09220	COG5342	invasion associated locus B
F9L69_RS09245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F9L69_RS09250	COG3257	ureidoglycine aminohydrolase activity
F9L69_RS09255	COG3195	allantoin biosynthetic process
F9L69_RS09255	COG3648	Uricase
F9L69_RS09265	COG2080	2 iron, 2 sulfur cluster binding
F9L69_RS09270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F9L69_RS09280	COG0583	DNA-binding transcription factor activity
F9L69_RS09355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9L69_RS09355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F9L69_RS09365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9L69_RS09365	COG2169	Transcriptional regulator
F9L69_RS09370	COG1393	Belongs to the ArsC family
F9L69_RS09380	COG0477	Major facilitator Superfamily
F9L69_RS09385	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F9L69_RS09410	COG3773	Cell wall hydrolase
F9L69_RS09430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F9L69_RS09470	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F9L69_RS09485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F9L69_RS09485	COG0616	signal peptide processing
F9L69_RS09505	COG0142	geranyltranstransferase activity
F9L69_RS09520	COG0751	glycine-tRNA ligase activity
F9L69_RS09525	COG0009	L-threonylcarbamoyladenylate synthase
F9L69_RS09560	COG1960	acyl-CoA dehydrogenase activity
F9L69_RS09575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F9L69_RS09590	COG0484	heat shock protein binding
F9L69_RS09595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F9L69_RS09610	COG1278	Cold shock
F9L69_RS09635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9L69_RS09635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9L69_RS09645	COG1722	exodeoxyribonuclease VII activity
F9L69_RS09665	COG1741	Belongs to the pirin family
F9L69_RS09675	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
F9L69_RS09680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F9L69_RS09700	COG5265	(ABC) transporter
F9L69_RS09710	COG1183	phosphatidylcholine synthase activity
F9L69_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS09720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F9L69_RS09740	COG0305	Participates in initiation and elongation during chromosome replication
F9L69_RS09745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9L69_RS09775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F9L69_RS09800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F9L69_RS09810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9L69_RS09815	COG1561	YicC-like family, N-terminal region
F9L69_RS09820	COG0194	GDP metabolic process
F9L69_RS09825	COG0312	modulator of DNA gyrase
F9L69_RS09835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9L69_RS09840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9L69_RS09875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F9L69_RS09890	COG0678	peroxiredoxin activity
F9L69_RS09890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9L69_RS09910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9L69_RS09915	COG0612	Peptidase, M16
F9L69_RS09930	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F9L69_RS09940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9L69_RS09950	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F9L69_RS09960	COG1194	a g-specific adenine glycosylase
F9L69_RS09980	COG1196	nuclear chromosome segregation
F9L69_RS09995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F9L69_RS09995	COG0574	Belongs to the PEP-utilizing enzyme family
F9L69_RS10020	COG1268	BioY protein
F9L69_RS10030	COG2351	hydroxyisourate hydrolase activity
F9L69_RS10045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F9L69_RS10105	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F9L69_RS10140	COG2801	Transposase and inactivated derivatives
F9L69_RS10145	COG2801	Transposase and inactivated derivatives
F9L69_RS10170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F9L69_RS10170	COG0662	Cupin 2, conserved barrel domain protein
F9L69_RS10175	COG2942	2-epimerase
F9L69_RS10180	COG0438	transferase activity, transferring glycosyl groups
F9L69_RS10180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F9L69_RS10200	COG1172	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS10205	COG1879	ABC-type sugar transport system periplasmic component
F9L69_RS10215	COG0673	inositol 2-dehydrogenase activity
F9L69_RS10225	COG1070	Carbohydrate kinase
F9L69_RS10250	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F9L69_RS10270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9L69_RS10290	COG2186	Transcriptional regulator
F9L69_RS10305	COG0433	COG0433 Predicted ATPase
F9L69_RS10310	COG1376	ErfK ybiS ycfS ynhG family protein
F9L69_RS10325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9L69_RS10340	COG4957	zinc ion binding
F9L69_RS10360	COG0154	amidase activity
F9L69_RS10365	COG2166	iron-sulfur cluster assembly
F9L69_RS10375	COG2205	protein histidine kinase activity
F9L69_RS10405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F9L69_RS10420	COG4695	Portal protein
F9L69_RS10540	COG3088	subunit of a heme lyase
F9L69_RS10545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9L69_RS10550	COG0745	RESPONSE REGULATOR receiver
F9L69_RS10560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F9L69_RS10590	COG1573	uracil-dna glycosylase
F9L69_RS10605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F9L69_RS10610	COG0625	glutathione transferase activity
F9L69_RS10645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F9L69_RS10650	COG4974	Belongs to the 'phage' integrase family
F9L69_RS10655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F9L69_RS10680	COG3743	rRNA binding
F9L69_RS10680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F9L69_RS10685	COG0741	lytic transglycosylase activity
F9L69_RS10725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9L69_RS10730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9L69_RS10735	COG2223	nitrite transmembrane transporter activity
F9L69_RS10740	COG2207	Transcriptional regulator
F9L69_RS10755	COG0681	Belongs to the peptidase S26 family
F9L69_RS10780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F9L69_RS10790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F9L69_RS10810	COG0494	nUDIX hydrolase
F9L69_RS10840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9L69_RS10860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F9L69_RS10865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9L69_RS10870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F9L69_RS10905	COG0488	(ABC) transporter
F9L69_RS10925	COG0314	molybdopterin synthase activity
F9L69_RS10930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F9L69_RS10950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9L69_RS10970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F9L69_RS10980	COG0243	molybdopterin cofactor binding
F9L69_RS10990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9L69_RS11005	COG1192	Involved in chromosome partitioning
F9L69_RS11015	COG1414	Transcriptional regulator
F9L69_RS11030	COG1957	nucleoside hydrolase
F9L69_RS11045	COG3845	ABC transporter
F9L69_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS11070	COG3433	isochorismatase activity
F9L69_RS11070	COG1535	isochorismatase
F9L69_RS11075	COG1021	2,3-dihydroxybenzoate-AMP ligase
F9L69_RS11080	COG1169	isochorismate synthase
F9L69_RS11085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9L69_RS11085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F9L69_RS11090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F9L69_RS11110	COG4944	Protein of unknown function (DUF1109)
F9L69_RS11115	COG2186	Transcriptional regulator
F9L69_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS11160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9L69_RS11165	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9L69_RS11170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F9L69_RS11205	COG4191	Histidine kinase
F9L69_RS11210	COG4566	intracellular signal transduction
F9L69_RS11230	COG0483	inositol monophosphate 1-phosphatase activity
F9L69_RS11260	COG0071	Belongs to the small heat shock protein (HSP20) family
F9L69_RS11275	COG0069	glutamate synthase activity
F9L69_RS11275	COG0067	glutamate synthase
F9L69_RS11275	COG0070	glutamate synthase
F9L69_RS11285	COG1113	amino acid transport
F9L69_RS11295	COG2885	chlorophyll binding
F9L69_RS11305	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F9L69_RS11310	COG2948	multi-organism process
F9L69_RS11330	COG3704	protein secretion by the type IV secretion system
F9L69_RS11355	COG0741	lytic transglycosylase activity
F9L69_RS11360	COG2951	lytic endotransglycosylase activity
F9L69_RS11365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F9L69_RS11385	COG0330	HflC and HflK could
F9L69_RS11420	COG2204	response regulator
F9L69_RS11430	COG3108	Peptidase M15
F9L69_RS11435	COG0800	Aldolase
F9L69_RS11455	COG0725	ABC transporter, periplasmic molybdate-binding protein
F9L69_RS11460	COG4149	molybdate abc transporter
F9L69_RS11465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F9L69_RS11485	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F9L69_RS11495	COG0583	DNA-binding transcription factor activity
F9L69_RS11500	COG0154	amidase activity
F9L69_RS11510	COG0489	protein tyrosine kinase activity
F9L69_RS11510	COG3206	protein involved in exopolysaccharide biosynthesis
F9L69_RS11545	COG0673	inositol 2-dehydrogenase activity
F9L69_RS11590	COG1309	transcriptional regulator
F9L69_RS11605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F9L69_RS11615	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F9L69_RS11630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F9L69_RS11640	COG4786	Flagellar basal body rod
F9L69_RS11645	COG1157	protein secretion by the type III secretion system
F9L69_RS11655	COG0671	phosphoesterase, PA-phosphatase related
F9L69_RS11670	COG0463	Glycosyl transferase, family 2
F9L69_RS11680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F9L69_RS11695	COG2963	transposase activity
F9L69_RS11700	COG2271	Major facilitator Superfamily
F9L69_RS11710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9L69_RS11715	COG1349	DNA-binding transcription factor activity
F9L69_RS11720	COG3622	Belongs to the hyi family
F9L69_RS11725	COG3395	kinase activity
F9L69_RS11730	COG2084	Dehydrogenase
F9L69_RS11735	COG1815	bacterial-type flagellum-dependent cell motility
F9L69_RS11740	COG1558	bacterial-type flagellum-dependent cell motility
F9L69_RS11750	COG4786	Flagellar basal body rod
F9L69_RS11755	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
F9L69_RS11765	COG1706	bacterial-type flagellum-dependent cell motility
F9L69_RS11785	COG1338	Plays a role in the flagellum-specific transport system
F9L69_RS11805	COG0583	DNA-binding transcription factor activity
F9L69_RS11815	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
F9L69_RS11830	COG3038	cytochrome b561
F9L69_RS11865	COG2186	Transcriptional regulator
F9L69_RS11870	COG0583	DNA-binding transcription factor activity
F9L69_RS11875	COG0277	FAD linked oxidase domain protein
F9L69_RS11890	COG0656	L-ascorbic acid biosynthetic process
F9L69_RS11900	COG1388	LysM domain
F9L69_RS11900	COG1376	ErfK ybiS ycfS ynhG family protein
F9L69_RS11905	COG2818	Glycosylase
F9L69_RS11940	COG2259	Doxx family
F9L69_RS11980	COG0196	riboflavin kinase activity
F9L69_RS11985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F9L69_RS12000	COG0590	tRNA wobble adenosine to inosine editing
F9L69_RS12010	COG0742	ribosomal rna small subunit methyltransferase
F9L69_RS12015	COG0612	Peptidase, M16
F9L69_RS12020	COG0612	Peptidase, M16
F9L69_RS12030	COG0475	glutathione-regulated potassium exporter activity
F9L69_RS12030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9L69_RS12035	COG0312	modulator of DNA gyrase
F9L69_RS12055	COG1519	Transferase
F9L69_RS12085	COG1960	acyl-CoA dehydrogenase activity
F9L69_RS12095	COG1024	Enoyl-CoA hydratase
F9L69_RS12105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9L69_RS12150	COG1477	protein flavinylation
F9L69_RS12175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9L69_RS12180	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F9L69_RS12195	COG1845	cytochrome c oxidase, subunit III
F9L69_RS12210	COG3256	nitric oxide reductase
F9L69_RS12215	COG0714	Associated with various cellular activities
F9L69_RS12220	COG4548	von Willebrand factor, type A
F9L69_RS12240	COG2151	metal-sulfur cluster biosynthetic enzyme
F9L69_RS12300	COG4214	carbohydrate transport
F9L69_RS12315	COG1069	ribulokinase activity
F9L69_RS12325	COG5654	RES domain protein
F9L69_RS12335	COG4178	(ABC) transporter
F9L69_RS12380	COG1477	protein flavinylation
F9L69_RS12405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9L69_RS12425	COG0826	peptidase U32
F9L69_RS12435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F9L69_RS12450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9L69_RS12455	COG2181	nitrate reductase activity
F9L69_RS12460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F9L69_RS12470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F9L69_RS12475	COG2223	nitrite transmembrane transporter activity
F9L69_RS12485	COG1609	Transcriptional regulator
F9L69_RS12490	COG1653	transport
F9L69_RS12535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9L69_RS12565	COG2894	cell division
F9L69_RS12590	COG3842	ATPase activity
F9L69_RS12595	COG1176	ABC-type spermidine putrescine transport system, permease component I
F9L69_RS12600	COG1177	transmembrane transport
F9L69_RS12650	COG0531	amino acid
F9L69_RS12670	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F9L69_RS12690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9L69_RS12695	COG3191	aminopeptidase activity
F9L69_RS12710	COG3258	Cytochrome c
F9L69_RS12715	COG0583	DNA-binding transcription factor activity
F9L69_RS12720	COG0753	catalase activity
F9L69_RS12780	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
F9L69_RS12785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9L69_RS12790	COG2124	cytochrome p450
F9L69_RS12795	COG1802	Transcriptional regulator
F9L69_RS12800	COG3321	synthase
F9L69_RS12800	COG0604	alcohol dehydrogenase
F9L69_RS12800	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS12825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F9L69_RS12840	COG0683	leucine binding
F9L69_RS12870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9L69_RS12885	COG0747	negative chemotaxis
F9L69_RS12890	COG2186	Transcriptional regulator
F9L69_RS12895	COG1940	carbohydrate kinase activity
F9L69_RS12895	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
F9L69_RS12900	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
F9L69_RS12915	COG2197	response regulator
F9L69_RS12935	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F9L69_RS12960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9L69_RS12965	COG0110	maltose O-acetyltransferase activity
F9L69_RS12985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F9L69_RS13025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9L69_RS13030	COG4310	Domain of unknown function (DUF2172)
F9L69_RS13050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F9L69_RS13055	COG2233	PERMEase
F9L69_RS13075	COG0583	DNA-binding transcription factor activity
F9L69_RS13080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9L69_RS13090	COG0183	Belongs to the thiolase family
F9L69_RS13100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9L69_RS13105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9L69_RS13120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9L69_RS13125	COG0242	peptide deformylase activity
F9L69_RS13130	COG2354	Protein conserved in bacteria
F9L69_RS13135	COG0640	Transcriptional regulator
F9L69_RS13175	COG0842	Transport permease protein
F9L69_RS13185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9L69_RS13220	COG2205	protein histidine kinase activity
F9L69_RS13265	COG1115	amino acid carrier protein
F9L69_RS13285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F9L69_RS13290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F9L69_RS13300	COG0156	8-amino-7-oxononanoate synthase activity
F9L69_RS13315	COG0521	Mo-molybdopterin cofactor biosynthetic process
F9L69_RS13330	COG2111	Na H antiporter
F9L69_RS13330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9L69_RS13335	COG1006	Multisubunit Na H antiporter MnhC subunit
F9L69_RS13340	COG0651	ATP synthesis coupled electron transport
F9L69_RS13350	COG2212	antiporter activity
F9L69_RS13370	COG4988	ABC transporter
F9L69_RS13375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F9L69_RS13380	COG1271	oxidase subunit
F9L69_RS13385	COG1294	oxidase, subunit
F9L69_RS13395	COG2188	Transcriptional regulator
F9L69_RS13400	COG2971	BadF BadG BcrA BcrD
F9L69_RS13415	COG1175	transmembrane transport
F9L69_RS13420	COG0395	ABC-type sugar transport system, permease component
F9L69_RS13425	COG0673	inositol 2-dehydrogenase activity
F9L69_RS13445	COG0022	dehydrogenase e1 component
F9L69_RS13480	COG0477	Major facilitator Superfamily
F9L69_RS13490	COG3145	DNA-N1-methyladenine dioxygenase activity
F9L69_RS13495	COG4172	Belongs to the ABC transporter superfamily
F9L69_RS13500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9L69_RS13505	COG0601	transmembrane transport
F9L69_RS13530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9L69_RS13545	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F9L69_RS13595	COG2433	Pfam Transposase IS66
F9L69_RS13600	COG3436	PFAM IS66 Orf2 family protein
F9L69_RS13605	COG2963	transposase activity
F9L69_RS13630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F9L69_RS13635	COG1959	2 iron, 2 sulfur cluster binding
F9L69_RS13670	COG4603	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS13675	COG3845	ABC transporter
F9L69_RS13685	COG1183	phosphatidylcholine synthase activity
F9L69_RS13690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9L69_RS13715	COG0346	lactoylglutathione lyase activity
F9L69_RS13720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9L69_RS13725	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F9L69_RS13735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9L69_RS13745	COG0785	Cytochrome C biogenesis protein
F9L69_RS13785	COG0697	spore germination
F9L69_RS13790	COG0187	DNA topoisomerase II activity
F9L69_RS13830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F9L69_RS13840	COG0758	DNA mediated transformation
F9L69_RS13845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F9L69_RS13845	COG1754	DNA topoisomerase type I activity
F9L69_RS13850	COG0557	exoribonuclease II activity
F9L69_RS13895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9L69_RS13935	COG2176	DNA-directed DNA polymerase activity
F9L69_RS13955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9L69_RS13985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9L69_RS13995	COG1414	Transcriptional regulator
F9L69_RS14010	COG0583	DNA-binding transcription factor activity
F9L69_RS14015	COG2267	carboxylic ester hydrolase activity
F9L69_RS14020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9L69_RS14030	COG3485	protocatechuate 3,4-dioxygenase
F9L69_RS14035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9L69_RS14040	COG0683	leucine binding
F9L69_RS14060	COG3842	ATPase activity
F9L69_RS14065	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F9L69_RS14080	COG1175	transmembrane transport
F9L69_RS14085	COG0395	ABC-type sugar transport system, permease component
F9L69_RS14095	COG3273	potassium ion transport
F9L69_RS14095	COG0471	metal ion transport
F9L69_RS14105	COG2252	PERMEase
F9L69_RS14125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F9L69_RS14160	COG4607	ABC-type enterochelin transport system periplasmic component
F9L69_RS14165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9L69_RS14170	COG4605	iron ion homeostasis
F9L69_RS14175	COG4604	ABC transporter, ATP-binding protein
F9L69_RS14190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9L69_RS14195	COG0765	amino acid transport
F9L69_RS14200	COG1126	abc transporter atp-binding protein
F9L69_RS14205	COG0248	Ppx GppA phosphatase
F9L69_RS14220	COG0477	Major facilitator Superfamily
F9L69_RS14230	COG3842	ATPase activity
F9L69_RS14235	COG0395	ABC-type sugar transport system, permease component
F9L69_RS14240	COG1175	transmembrane transport
F9L69_RS14245	COG1653	transport
F9L69_RS14275	COG1840	ABC-type Fe3 transport system, periplasmic component
F9L69_RS14300	COG2132	Multicopper oxidase
F9L69_RS14315	COG0477	Major facilitator Superfamily
F9L69_RS14325	COG0450	alkyl hydroperoxide reductase
F9L69_RS14340	COG0673	inositol 2-dehydrogenase activity
F9L69_RS14350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9L69_RS14355	COG3962	Belongs to the TPP enzyme family
F9L69_RS14365	COG3718	enzyme involved in inositol metabolism
F9L69_RS14375	COG3842	ATPase activity
F9L69_RS14385	COG1840	ABC-type Fe3 transport system, periplasmic component
F9L69_RS14395	COG1522	sequence-specific DNA binding
F9L69_RS14415	COG0509	glycine decarboxylation via glycine cleavage system
F9L69_RS14420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F9L69_RS14475	COG4176	ABC-type proline glycine betaine transport system permease component
F9L69_RS14500	COG1737	Transcriptional regulator
F9L69_RS14525	COG0395	ABC-type sugar transport system, permease component
F9L69_RS14530	COG0251	oxidation-reduction process
F9L69_RS14545	COG1120	ATPase activity
F9L69_RS14550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9L69_RS14580	COG1846	Transcriptional regulator
F9L69_RS14615	COG0174	glutamine synthetase
F9L69_RS14625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9L69_RS14670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F9L69_RS14675	COG0363	glucosamine-6-phosphate deaminase activity
F9L69_RS14680	COG0129	dihydroxy-acid dehydratase activity
F9L69_RS14695	COG4172	Belongs to the ABC transporter superfamily
F9L69_RS14705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9L69_RS14715	COG0747	negative chemotaxis
F9L69_RS14725	COG0288	reversible hydration of carbon dioxide
F9L69_RS14750	COG1024	Enoyl-CoA hydratase
F9L69_RS14750	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9L69_RS14755	COG0183	Belongs to the thiolase family
F9L69_RS14760	COG1960	acyl-CoA dehydrogenase activity
F9L69_RS14800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9L69_RS14805	COG0601	transmembrane transport
F9L69_RS14810	COG0747	negative chemotaxis
F9L69_RS14825	COG4208	sulfate ABC transporter
F9L69_RS14835	COG3842	ATPase activity
F9L69_RS14845	COG0246	Mannitol dehydrogenase
F9L69_RS14855	COG1904	glucuronate isomerase
F9L69_RS14860	COG1802	Transcriptional regulator
F9L69_RS14875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9L69_RS14890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F9L69_RS14895	COG1993	acr, cog1993
F9L69_RS14900	COG0789	Transcriptional regulator
F9L69_RS14910	COG0730	response to heat
F9L69_RS14925	COG1201	RNA secondary structure unwinding
F9L69_RS15000	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F9L69_RS15010	COG3586	endonuclease activity
F9L69_RS15045	COG1088	dTDP-glucose 4,6-dehydratase activity
F9L69_RS15055	COG0277	FAD linked oxidase domain protein
F9L69_RS15060	COG0546	phosphoglycolate phosphatase activity
F9L69_RS15060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F9L69_RS15065	COG1349	DNA-binding transcription factor activity
F9L69_RS15080	COG1172	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS15085	COG1129	ABC transporter
F9L69_RS15120	COG1349	DNA-binding transcription factor activity
F9L69_RS15150	COG1217	gtp-binding protein TYPA
F9L69_RS15155	COG2239	Acts as a magnesium transporter
F9L69_RS15165	COG0339	signal peptide processing
F9L69_RS15200	COG1764	response to oxidative stress
F9L69_RS15205	COG1846	Transcriptional regulator
F9L69_RS15210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F9L69_RS15220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9L69_RS15220	COG2169	Transcriptional regulator
F9L69_RS15270	COG2423	ornithine cyclodeaminase activity
F9L69_RS15275	COG0010	Belongs to the arginase family
F9L69_RS15285	COG1902	pentaerythritol trinitrate reductase activity
F9L69_RS15290	COG0640	Transcriptional regulator
F9L69_RS15300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9L69_RS15315	COG5383	Protein conserved in bacteria
F9L69_RS15315	COG5383	Protein conserved in bacteria
F9L69_RS15320	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS15340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F9L69_RS15345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9L69_RS15360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9L69_RS15380	COG0243	molybdopterin cofactor binding
F9L69_RS15390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9L69_RS15395	COG1522	sequence-specific DNA binding
F9L69_RS15460	COG4214	carbohydrate transport
F9L69_RS15475	COG0800	Aldolase
F9L69_RS15480	COG3734	2-keto-3-deoxy-galactonokinase
F9L69_RS15485	COG0129	dihydroxy-acid dehydratase activity
F9L69_RS15500	COG1172	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS15505	COG2186	Transcriptional regulator
F9L69_RS15510	COG0028	Belongs to the TPP enzyme family
F9L69_RS15520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9L69_RS15585	COG2011	ABC-type metal ion transport system permease component
F9L69_RS15670	COG5001	Diguanylate cyclase
F9L69_RS15675	COG1028	Short-chain dehydrogenase reductase Sdr
F9L69_RS15690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9L69_RS15695	COG1609	Transcriptional regulator
F9L69_RS15715	COG0523	cobalamin synthesis protein
F9L69_RS15725	COG0400	carboxylic ester hydrolase activity
F9L69_RS15730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F9L69_RS15740	COG0251	oxidation-reduction process
F9L69_RS15745	COG1172	Belongs to the binding-protein-dependent transport system permease family
F9L69_RS15755	COG1129	ABC transporter
F9L69_RS15760	COG1129	ABC transporter
F9L69_RS15765	COG1879	ABC-type sugar transport system periplasmic component
F9L69_RS15805	COG3706	GGDEF domain
F9L69_RS15810	COG0579	oxidoreductase
F9L69_RS15815	COG2176	DNA-directed DNA polymerase activity
F9L69_RS15820	COG0154	amidase activity
F9L69_RS15830	COG4608	Belongs to the ABC transporter superfamily
F9L69_RS15835	COG0444	Belongs to the ABC transporter superfamily
F9L69_RS15860	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS15865	COG1802	Transcriptional regulator
F9L69_RS15870	COG2814	Major facilitator Superfamily
F9L69_RS15890	COG0251	oxidation-reduction process
F9L69_RS15915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F9L69_RS15965	COG0242	peptide deformylase activity
F9L69_RS15980	COG2827	Endonuclease containing a URI domain
F9L69_RS16015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9L69_RS16035	COG0837	glucose binding
F9L69_RS16040	COG1132	(ABC) transporter
F9L69_RS16045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F9L69_RS16070	COG0778	Nitroreductase
F9L69_RS16105	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9L69_RS16110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F9L69_RS16115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9L69_RS16160	COG0277	FAD linked oxidase domain protein
F9L69_RS16170	COG2337	Toxic component of a toxin-antitoxin (TA) module
F9L69_RS16185	COG0235	Class ii aldolase
F9L69_RS16210	COG1176	ABC-type spermidine putrescine transport system, permease component I
F9L69_RS16215	COG1177	transmembrane transport
F9L69_RS16225	COG0154	amidase activity
F9L69_RS16230	COG3386	PFAM SMP-30 Gluconolaconase
F9L69_RS16235	COG4608	Belongs to the ABC transporter superfamily
F9L69_RS16240	COG0444	Belongs to the ABC transporter superfamily
F9L69_RS16250	COG0601	transmembrane transport
F9L69_RS16255	COG0747	negative chemotaxis
F9L69_RS16275	COG0444	Belongs to the ABC transporter superfamily
F9L69_RS16290	COG0747	negative chemotaxis
F9L69_RS16315	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9L69_RS16320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9L69_RS16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9L69_RS16345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9L69_RS16350	COG0444	Belongs to the ABC transporter superfamily
F9L69_RS16355	COG4608	Belongs to the ABC transporter superfamily
F9L69_RS16360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9L69_RS16415	COG2971	BadF BadG BcrA BcrD
F9L69_RS16420	COG1959	2 iron, 2 sulfur cluster binding
F9L69_RS16425	COG0523	cobalamin synthesis protein
F9L69_RS16440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9L69_RS16445	COG0735	belongs to the Fur family
F9L69_RS16495	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F9L69_RS16545	COG1360	Flagellar Motor Protein
F9L69_RS16565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9L69_RS16580	COG4213	ABC transporter substrate-binding protein
F9L69_RS16585	COG1129	ABC transporter
F9L69_RS16590	COG4214	carbohydrate transport
F9L69_RS16615	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F9L69_RS16625	COG3971	2-oxopent-4-enoate hydratase activity
F9L69_RS16630	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9L69_RS16650	COG1846	Transcriptional regulator
F9L69_RS16655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F9L69_RS16660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9L69_RS16675	COG5441	Belongs to the UPF0261 family
F9L69_RS16685	COG0531	amino acid
F9L69_RS16690	COG1012	belongs to the aldehyde dehydrogenase family
F9L69_RS16695	COG1228	amidohydrolase
F9L69_RS16730	COG2188	Transcriptional regulator
F9L69_RS16735	COG1653	transport
F9L69_RS16740	COG3833	ABC-type maltose transport systems, permease component
F9L69_RS16745	COG1175	transmembrane transport
F9L69_RS16750	COG3842	ATPase activity
F9L69_RS16770	COG1116	anion transmembrane transporter activity
F9L69_RS16785	COG4206	TonB-dependent receptor
F9L69_RS16815	COG0411	ABC transporter
F9L69_RS16830	COG0635	Involved in the biosynthesis of porphyrin-containing compound