locus-tag	class	description
BKD03_RS00070	COG1228	amidohydrolase
BKD03_RS00105	COG0778	Nitroreductase
BKD03_RS00130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKD03_RS00140	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BKD03_RS00145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKD03_RS00150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKD03_RS00210	COG0644	oxidoreductase
BKD03_RS00270	COG0789	Transcriptional regulator
BKD03_RS00370	COG2971	BadF BadG BcrA BcrD
BKD03_RS00375	COG1959	2 iron, 2 sulfur cluster binding
BKD03_RS00380	COG0523	cobalamin synthesis protein
BKD03_RS00395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKD03_RS00400	COG0735	belongs to the Fur family
BKD03_RS00435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKD03_RS00445	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKD03_RS00495	COG1360	Flagellar Motor Protein
BKD03_RS00510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKD03_RS00525	COG4213	ABC transporter substrate-binding protein
BKD03_RS00535	COG4214	carbohydrate transport
BKD03_RS00575	COG0411	ABC transporter
BKD03_RS00610	COG3971	2-oxopent-4-enoate hydratase activity
BKD03_RS00615	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKD03_RS00635	COG1846	Transcriptional regulator
BKD03_RS00640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKD03_RS00645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD03_RS00665	COG2188	Transcriptional regulator
BKD03_RS00670	COG1653	transport
BKD03_RS00680	COG1175	transmembrane transport
BKD03_RS00685	COG3842	ATPase activity
BKD03_RS00725	COG4122	O-methyltransferase activity
BKD03_RS00770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD03_RS00780	COG1192	Involved in chromosome partitioning
BKD03_RS00785	COG1475	DNA binding
BKD03_RS00790	COG1414	Transcriptional regulator
BKD03_RS00800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD03_RS00805	COG1957	nucleoside hydrolase
BKD03_RS00810	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKD03_RS00820	COG3845	ABC transporter
BKD03_RS00825	COG1744	ABC transporter substrate-binding protein PnrA-like
BKD03_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
BKD03_RS00845	COG1535	isochorismatase
BKD03_RS00845	COG3433	isochorismatase activity
BKD03_RS00850	COG1021	2,3-dihydroxybenzoate-AMP ligase
BKD03_RS00855	COG1169	isochorismate synthase
BKD03_RS00860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKD03_RS00860	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BKD03_RS00865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKD03_RS00885	COG4944	Protein of unknown function (DUF1109)
BKD03_RS00890	COG2186	Transcriptional regulator
BKD03_RS00925	COG1028	Short-chain dehydrogenase reductase Sdr
BKD03_RS00930	COG1028	Short-chain dehydrogenase reductase Sdr
BKD03_RS00935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKD03_RS00940	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD03_RS00945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD03_RS00980	COG4191	Histidine kinase
BKD03_RS00985	COG4566	intracellular signal transduction
BKD03_RS01005	COG0483	inositol monophosphate 1-phosphatase activity
BKD03_RS01035	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD03_RS01050	COG0069	glutamate synthase activity
BKD03_RS01050	COG0070	glutamate synthase
BKD03_RS01050	COG0067	glutamate synthase
BKD03_RS01060	COG1113	amino acid transport
BKD03_RS01085	COG2948	multi-organism process
BKD03_RS01135	COG2951	lytic endotransglycosylase activity
BKD03_RS01140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKD03_RS01160	COG0330	HflC and HflK could
BKD03_RS01175	COG5310	Homospermidine synthase
BKD03_RS01195	COG2204	response regulator
BKD03_RS01205	COG3108	Peptidase M15
BKD03_RS01210	COG0800	Aldolase
BKD03_RS01230	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKD03_RS01235	COG4149	molybdate abc transporter
BKD03_RS01240	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BKD03_RS01255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BKD03_RS01265	COG0583	DNA-binding transcription factor activity
BKD03_RS01270	COG0154	amidase activity
BKD03_RS01280	COG0489	protein tyrosine kinase activity
BKD03_RS01280	COG3206	protein involved in exopolysaccharide biosynthesis
BKD03_RS01315	COG0673	inositol 2-dehydrogenase activity
BKD03_RS01355	COG1309	transcriptional regulator
BKD03_RS01370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKD03_RS01375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD03_RS01380	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKD03_RS01395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKD03_RS01405	COG4786	Flagellar basal body rod
BKD03_RS01410	COG1157	protein secretion by the type III secretion system
BKD03_RS01420	COG0671	phosphoesterase, PA-phosphatase related
BKD03_RS01455	COG2963	transposase activity
BKD03_RS01460	COG2271	Major facilitator Superfamily
BKD03_RS01465	COG0235	Class ii aldolase
BKD03_RS01470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD03_RS01475	COG1349	DNA-binding transcription factor activity
BKD03_RS01480	COG3622	Belongs to the hyi family
BKD03_RS01485	COG3395	kinase activity
BKD03_RS01490	COG2084	Dehydrogenase
BKD03_RS01495	COG1815	bacterial-type flagellum-dependent cell motility
BKD03_RS01500	COG1558	bacterial-type flagellum-dependent cell motility
BKD03_RS01505	COG1677	Flagellar hook-basal body complex protein FliE
BKD03_RS01510	COG4786	Flagellar basal body rod
BKD03_RS01515	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BKD03_RS01520	COG1706	bacterial-type flagellum-dependent cell motility
BKD03_RS01540	COG1338	Plays a role in the flagellum-specific transport system
BKD03_RS01585	COG2186	Transcriptional regulator
BKD03_RS01590	COG0583	DNA-binding transcription factor activity
BKD03_RS01600	COG0583	DNA-binding transcription factor activity
BKD03_RS01610	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BKD03_RS01620	COG3038	cytochrome b561
BKD03_RS01630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKD03_RS01645	COG0523	cobalamin synthesis protein
BKD03_RS01655	COG1846	Transcriptional regulator
BKD03_RS01660	COG1609	Transcriptional regulator
BKD03_RS01670	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKD03_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
BKD03_RS01755	COG2011	ABC-type metal ion transport system permease component
BKD03_RS01820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD03_RS01830	COG0028	Belongs to the TPP enzyme family
BKD03_RS01835	COG2186	Transcriptional regulator
BKD03_RS01860	COG3734	2-keto-3-deoxy-galactonokinase
BKD03_RS01865	COG0800	Aldolase
BKD03_RS01870	COG4213	ABC transporter substrate-binding protein
BKD03_RS01880	COG4214	carbohydrate transport
BKD03_RS01915	COG0402	S-adenosylhomocysteine deaminase activity
BKD03_RS01945	COG1522	sequence-specific DNA binding
BKD03_RS01950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD03_RS01970	COG0243	molybdopterin cofactor binding
BKD03_RS01990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD03_RS02000	COG2188	Transcriptional regulator
BKD03_RS02010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKD03_RS02030	COG1012	belongs to the aldehyde dehydrogenase family
BKD03_RS02035	COG5383	Protein conserved in bacteria
BKD03_RS02050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD03_RS02055	COG2183	response to ionizing radiation
BKD03_RS02060	COG0640	Transcriptional regulator
BKD03_RS02065	COG1902	pentaerythritol trinitrate reductase activity
BKD03_RS02075	COG0010	Belongs to the arginase family
BKD03_RS02125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKD03_RS02125	COG2169	Transcriptional regulator
BKD03_RS02135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKD03_RS02140	COG1846	Transcriptional regulator
BKD03_RS02145	COG1764	response to oxidative stress
BKD03_RS02180	COG0339	signal peptide processing
BKD03_RS02190	COG2239	Acts as a magnesium transporter
BKD03_RS02195	COG1217	gtp-binding protein TYPA
BKD03_RS02230	COG1349	DNA-binding transcription factor activity
BKD03_RS02265	COG1129	ABC transporter
BKD03_RS02270	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD03_RS02285	COG1349	DNA-binding transcription factor activity
BKD03_RS02320	COG0277	FAD linked oxidase domain protein
BKD03_RS02335	COG1609	Transcriptional regulator
BKD03_RS02340	COG1653	transport
BKD03_RS02365	COG0673	inositol 2-dehydrogenase activity
BKD03_RS02380	COG2814	Major facilitator Superfamily
BKD03_RS02390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BKD03_RS02420	COG2894	cell division
BKD03_RS02450	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD03_RS02455	COG1177	transmembrane transport
BKD03_RS02495	COG0076	glutamate decarboxylase activity
BKD03_RS02500	COG0531	amino acid
BKD03_RS02525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BKD03_RS02545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKD03_RS02550	COG3191	aminopeptidase activity
BKD03_RS02565	COG3258	Cytochrome c
BKD03_RS02570	COG0583	DNA-binding transcription factor activity
BKD03_RS02575	COG0753	catalase activity
BKD03_RS02585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKD03_RS02585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKD03_RS02615	COG5489	Protein of unknown function (DUF736)
BKD03_RS02625	COG4453	Protein conserved in bacteria
BKD03_RS02670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKD03_RS02705	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BKD03_RS02710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKD03_RS02725	COG1802	Transcriptional regulator
BKD03_RS02735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD03_RS02780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD03_RS02800	COG2186	Transcriptional regulator
BKD03_RS02805	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BKD03_RS02805	COG1940	carbohydrate kinase activity
BKD03_RS02825	COG2197	response regulator
BKD03_RS02840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKD03_RS02845	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BKD03_RS02870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD03_RS02875	COG0110	maltose O-acetyltransferase activity
BKD03_RS02895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKD03_RS02920	COG0438	transferase activity, transferring glycosyl groups
BKD03_RS02935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKD03_RS02940	COG4310	Domain of unknown function (DUF2172)
BKD03_RS02945	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BKD03_RS02960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKD03_RS02965	COG2233	PERMEase
BKD03_RS02975	COG2814	Major facilitator Superfamily
BKD03_RS02980	COG0583	DNA-binding transcription factor activity
BKD03_RS02985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKD03_RS02990	COG1960	acyl-CoA dehydrogenase activity
BKD03_RS02995	COG0183	Belongs to the thiolase family
BKD03_RS03005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKD03_RS03020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD03_RS03025	COG0242	peptide deformylase activity
BKD03_RS03030	COG2354	Protein conserved in bacteria
BKD03_RS03035	COG0640	Transcriptional regulator
BKD03_RS03075	COG1131	(ABC) transporter
BKD03_RS03090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD03_RS03125	COG3189	MarR family transcriptional regulator
BKD03_RS03130	COG1252	NADH dehydrogenase
BKD03_RS03150	COG1115	amino acid carrier protein
BKD03_RS03170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKD03_RS03175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD03_RS03185	COG0156	8-amino-7-oxononanoate synthase activity
BKD03_RS03195	COG0477	Major facilitator Superfamily
BKD03_RS03210	COG2132	Multicopper oxidase
BKD03_RS03225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD03_RS03230	COG3842	ATPase activity
BKD03_RS03235	COG1840	ABC-type Fe3 transport system, periplasmic component
BKD03_RS03270	COG1175	transmembrane transport
BKD03_RS03275	COG0395	ABC-type sugar transport system, permease component
BKD03_RS03280	COG3842	ATPase activity
BKD03_RS03290	COG0477	Major facilitator Superfamily
BKD03_RS03305	COG0248	Ppx GppA phosphatase
BKD03_RS03310	COG1126	abc transporter atp-binding protein
BKD03_RS03315	COG0765	amino acid transport
BKD03_RS03320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD03_RS03335	COG4604	ABC transporter, ATP-binding protein
BKD03_RS03340	COG4605	iron ion homeostasis
BKD03_RS03345	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKD03_RS03350	COG4607	ABC-type enterochelin transport system periplasmic component
BKD03_RS03385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKD03_RS03410	COG2252	PERMEase
BKD03_RS03420	COG3273	potassium ion transport
BKD03_RS03420	COG0471	metal ion transport
BKD03_RS03455	COG3842	ATPase activity
BKD03_RS03475	COG0683	leucine binding
BKD03_RS03480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKD03_RS03485	COG3485	protocatechuate 3,4-dioxygenase
BKD03_RS03490	COG3485	protocatechuate 3,4-dioxygenase
BKD03_RS03495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKD03_RS03500	COG2267	carboxylic ester hydrolase activity
BKD03_RS03505	COG0583	DNA-binding transcription factor activity
BKD03_RS03520	COG1414	Transcriptional regulator
BKD03_RS03530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKD03_RS03560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD03_RS03565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD03_RS03585	COG2176	DNA-directed DNA polymerase activity
BKD03_RS03630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKD03_RS03635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKD03_RS03675	COG0557	exoribonuclease II activity
BKD03_RS03680	COG1754	DNA topoisomerase type I activity
BKD03_RS03680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKD03_RS03685	COG0758	DNA mediated transformation
BKD03_RS03695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKD03_RS03705	COG1960	acyl-CoA dehydrogenase activity
BKD03_RS03740	COG0187	DNA topoisomerase II activity
BKD03_RS03745	COG0697	spore germination
BKD03_RS03775	COG0210	DNA helicase
BKD03_RS03810	COG0785	Cytochrome C biogenesis protein
BKD03_RS03830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BKD03_RS03835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKD03_RS03865	COG0022	dehydrogenase e1 component
BKD03_RS03905	COG0477	Major facilitator Superfamily
BKD03_RS03915	COG3145	DNA-N1-methyladenine dioxygenase activity
BKD03_RS03920	COG4172	Belongs to the ABC transporter superfamily
BKD03_RS03925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD03_RS03930	COG0601	transmembrane transport
BKD03_RS03970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKD03_RS04025	COG1476	TRANSCRIPTIONal
BKD03_RS04035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD03_RS04085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKD03_RS04090	COG1959	2 iron, 2 sulfur cluster binding
BKD03_RS04130	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKD03_RS04135	COG3845	ABC transporter
BKD03_RS04145	COG1183	phosphatidylcholine synthase activity
BKD03_RS04150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD03_RS04165	COG0673	inositol 2-dehydrogenase activity
BKD03_RS04170	COG0395	ABC-type sugar transport system, permease component
BKD03_RS04175	COG1175	transmembrane transport
BKD03_RS04190	COG2971	BadF BadG BcrA BcrD
BKD03_RS04195	COG2188	Transcriptional regulator
BKD03_RS04205	COG1294	oxidase, subunit
BKD03_RS04210	COG1271	oxidase subunit
BKD03_RS04215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKD03_RS04220	COG4988	ABC transporter
BKD03_RS04235	COG2212	antiporter activity
BKD03_RS04240	COG1863	multisubunit Na H antiporter MnhE subunit
BKD03_RS04245	COG0651	ATP synthesis coupled electron transport
BKD03_RS04250	COG1006	Multisubunit Na H antiporter MnhC subunit
BKD03_RS04255	COG2111	Na H antiporter
BKD03_RS04255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKD03_RS04270	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKD03_RS04300	COG0450	alkyl hydroperoxide reductase
BKD03_RS04315	COG0673	inositol 2-dehydrogenase activity
BKD03_RS04325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD03_RS04330	COG3962	Belongs to the TPP enzyme family
BKD03_RS04340	COG3718	enzyme involved in inositol metabolism
BKD03_RS04360	COG1840	ABC-type Fe3 transport system, periplasmic component
BKD03_RS04370	COG1522	sequence-specific DNA binding
BKD03_RS04385	COG0509	glycine decarboxylation via glycine cleavage system
BKD03_RS04390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKD03_RS04445	COG4176	ABC-type proline glycine betaine transport system permease component
BKD03_RS04470	COG1737	Transcriptional regulator
BKD03_RS04495	COG0395	ABC-type sugar transport system, permease component
BKD03_RS04515	COG1120	ATPase activity
BKD03_RS04550	COG1846	Transcriptional regulator
BKD03_RS04570	COG0583	DNA-binding transcription factor activity
BKD03_RS04585	COG0174	glutamine synthetase
BKD03_RS04595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD03_RS04640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKD03_RS04645	COG0363	glucosamine-6-phosphate deaminase activity
BKD03_RS04665	COG4172	Belongs to the ABC transporter superfamily
BKD03_RS04670	COG0444	Belongs to the ABC transporter superfamily
BKD03_RS04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD03_RS04685	COG0747	negative chemotaxis
BKD03_RS04695	COG0288	reversible hydration of carbon dioxide
BKD03_RS04720	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD03_RS04720	COG1024	Enoyl-CoA hydratase
BKD03_RS04725	COG0183	Belongs to the thiolase family
BKD03_RS04730	COG1960	acyl-CoA dehydrogenase activity
BKD03_RS04740	COG0583	DNA-binding transcription factor activity
BKD03_RS04760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD03_RS04765	COG0601	transmembrane transport
BKD03_RS04770	COG0747	negative chemotaxis
BKD03_RS04785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD03_RS04805	COG1993	acr, cog1993
BKD03_RS04810	COG0789	Transcriptional regulator
BKD03_RS04820	COG0730	response to heat
BKD03_RS04835	COG1201	RNA secondary structure unwinding
BKD03_RS04890	COG2819	hydrolase of the alpha beta superfamily
BKD03_RS04905	COG4592	Periplasmic binding protein
BKD03_RS04910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKD03_RS04915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKD03_RS04920	COG1120	ATPase activity
BKD03_RS04930	COG4585	Histidine kinase
BKD03_RS04950	COG2223	nitrite transmembrane transporter activity
BKD03_RS04955	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKD03_RS04960	COG1140	nitrate reductase beta subunit
BKD03_RS04965	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKD03_RS04970	COG2181	nitrate reductase activity
BKD03_RS04975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD03_RS04990	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BKD03_RS05000	COG0826	peptidase U32
BKD03_RS05015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD03_RS05045	COG1477	protein flavinylation
BKD03_RS05085	COG4178	(ABC) transporter
BKD03_RS05095	COG5654	RES domain protein
BKD03_RS05140	COG2151	metal-sulfur cluster biosynthetic enzyme
BKD03_RS05170	COG0714	Associated with various cellular activities
BKD03_RS05175	COG3256	nitric oxide reductase
BKD03_RS05190	COG1845	cytochrome c oxidase, subunit III
BKD03_RS05210	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BKD03_RS05215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKD03_RS05240	COG1477	protein flavinylation
BKD03_RS05285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD03_RS05290	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD03_RS05295	COG1024	Enoyl-CoA hydratase
BKD03_RS05305	COG1960	acyl-CoA dehydrogenase activity
BKD03_RS05310	COG2814	Major facilitator Superfamily
BKD03_RS05335	COG1519	Transferase
BKD03_RS05355	COG0312	modulator of DNA gyrase
BKD03_RS05360	COG0475	glutathione-regulated potassium exporter activity
BKD03_RS05360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKD03_RS05370	COG0612	Peptidase, M16
BKD03_RS05375	COG0612	Peptidase, M16
BKD03_RS05380	COG0742	ribosomal rna small subunit methyltransferase
BKD03_RS05390	COG0590	tRNA wobble adenosine to inosine editing
BKD03_RS05410	COG0196	riboflavin kinase activity
BKD03_RS05450	COG2259	Doxx family
BKD03_RS05490	COG2818	Glycosylase
BKD03_RS05495	COG1376	ErfK ybiS ycfS ynhG family protein
BKD03_RS05495	COG1388	LysM domain
BKD03_RS05505	COG0656	L-ascorbic acid biosynthetic process
BKD03_RS05510	COG0247	lactate metabolic process
BKD03_RS05520	COG0277	FAD linked oxidase domain protein
BKD03_RS05535	COG1126	abc transporter atp-binding protein
BKD03_RS05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD03_RS05545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKD03_RS05545	COG0723	plastoquinol--plastocyanin reductase activity
BKD03_RS05550	COG0765	amino acid transport
BKD03_RS05555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKD03_RS05560	COG1473	amidohydrolase
BKD03_RS05595	COG3706	GGDEF domain
BKD03_RS05600	COG0579	oxidoreductase
BKD03_RS05605	COG2176	DNA-directed DNA polymerase activity
BKD03_RS05610	COG0154	amidase activity
BKD03_RS05615	COG4608	Belongs to the ABC transporter superfamily
BKD03_RS05620	COG0444	Belongs to the ABC transporter superfamily
BKD03_RS05625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD03_RS05650	COG1802	Transcriptional regulator
BKD03_RS05655	COG2814	Major facilitator Superfamily
BKD03_RS05695	COG0251	oxidation-reduction process
BKD03_RS05725	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKD03_RS05780	COG0242	peptide deformylase activity
BKD03_RS05825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKD03_RS05875	COG1228	amidohydrolase
BKD03_RS05900	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BKD03_RS05905	COG1136	(ABC) transporter
BKD03_RS06785	COG2217	Heavy metal translocating P-type atpase
BKD03_RS06840	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKD03_RS06965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKD03_RS06975	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD03_RS06985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKD03_RS07710	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BKD03_RS07810	COG2011	ABC-type metal ion transport system permease component
BKD03_RS07960	COG4213	ABC transporter substrate-binding protein
BKD03_RS08210	COG2183	response to ionizing radiation
BKD03_RS08790	COG4453	Protein conserved in bacteria
BKD03_RS09130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKD03_RS09285	COG1131	(ABC) transporter
BKD03_RS09380	COG0477	Major facilitator Superfamily
BKD03_RS09385	COG0477	Major facilitator Superfamily
BKD03_RS09970	COG0187	DNA topoisomerase II activity
BKD03_RS10030	COG0210	DNA helicase
BKD03_RS10205	COG0477	Major facilitator Superfamily
BKD03_RS10370	COG1183	phosphatidylcholine synthase activity
BKD03_RS10455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKD03_RS10485	COG0651	ATP synthesis coupled electron transport
BKD03_RS10605	COG1178	ABC-type Fe3 transport system permease component
BKD03_RS10680	COG1454	alcohol dehydrogenase
BKD03_RS11005	COG0747	negative chemotaxis
BKD03_RS11725	COG0742	ribosomal rna small subunit methyltransferase
BKD03_RS11875	COG0656	L-ascorbic acid biosynthetic process
BKD03_RS11925	COG1012	belongs to the aldehyde dehydrogenase family
BKD03_RS12035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD03_RS12445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD03_RS12725	COG0719	Fe-S assembly protein
BKD03_RS12775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKD03_RS13025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD03_RS13065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD03_RS13570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKD03_RS13715	COG0243	molybdopterin cofactor binding
BKD03_RS14160	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKD03_RS14910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKD03_RS14920	COG0305	Participates in initiation and elongation during chromosome replication
BKD03_RS14950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKD03_RS15460	COG0583	DNA-binding transcription factor activity
BKD03_RS15510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKD03_RS15840	COG3617	BRO family, N-terminal domain
BKD03_RS16550	COG0728	peptidoglycan biosynthetic process
BKD03_RS17160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD03_RS17275	COG0539	negative regulation of cytoplasmic translation