locus-tag	class	description
BKD02_RS00015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD02_RS00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKD02_RS00055	COG2095	MarC family integral membrane protein
BKD02_RS00080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKD02_RS00110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKD02_RS00130	COG0569	domain protein
BKD02_RS00135	COG2204	response regulator
BKD02_RS00140	COG5000	phosphorelay sensor kinase activity
BKD02_RS00145	COG2204	response regulator
BKD02_RS00150	COG3852	Histidine kinase
BKD02_RS00165	COG1058	Belongs to the CinA family
BKD02_RS00165	COG1546	Belongs to the CinA family
BKD02_RS00170	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS00175	COG2867	negative regulation of translational initiation
BKD02_RS00190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKD02_RS00195	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD02_RS00200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD02_RS00200	COG0022	dehydrogenase e1 component
BKD02_RS00205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKD02_RS00210	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BKD02_RS00215	COG2151	metal-sulfur cluster biosynthetic enzyme
BKD02_RS00220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKD02_RS00225	COG0719	Fe-S assembly protein
BKD02_RS00230	COG0396	ATPase activity
BKD02_RS00235	COG0719	Fe-S assembly protein
BKD02_RS00245	COG2945	thiolester hydrolase activity
BKD02_RS00255	COG3293	Transposase
BKD02_RS00280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKD02_RS00285	COG2833	Protein of unknown function (DUF455)
BKD02_RS00305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKD02_RS00310	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKD02_RS00320	COG1530	ribonuclease E activity
BKD02_RS00325	COG0436	Aminotransferase
BKD02_RS00330	COG0501	Belongs to the peptidase M48B family
BKD02_RS00345	COG0511	ligase activity, forming carbon-carbon bonds
BKD02_RS00350	COG0439	Biotin carboxylase
BKD02_RS00360	COG4765	Protein conserved in bacteria
BKD02_RS00380	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKD02_RS00625	COG1862	Preprotein translocase
BKD02_RS00645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD02_RS00660	COG0805	protein transport
BKD02_RS00665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKD02_RS00675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKD02_RS00680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKD02_RS00685	COG1472	Belongs to the glycosyl hydrolase 3 family
BKD02_RS00705	COG0316	Belongs to the HesB IscA family
BKD02_RS00735	COG1573	uracil-dna glycosylase
BKD02_RS00740	COG1522	sequence-specific DNA binding
BKD02_RS00765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKD02_RS00795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKD02_RS00800	COG3454	Phosphonate metabolism
BKD02_RS00805	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BKD02_RS00810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD02_RS00830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKD02_RS00835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD02_RS00840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD02_RS00860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKD02_RS00865	COG2514	catechol 2,3-dioxygenase activity
BKD02_RS00895	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKD02_RS00945	COG2814	Major facilitator Superfamily
BKD02_RS00950	COG0483	inositol monophosphate 1-phosphatase activity
BKD02_RS00960	COG1487	ribonuclease activity
BKD02_RS01015	COG0346	lactoylglutathione lyase activity
BKD02_RS01030	COG1007	ATP synthesis coupled electron transport
BKD02_RS01070	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BKD02_RS01075	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BKD02_RS01095	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BKD02_RS01150	COG0010	Belongs to the arginase family
BKD02_RS01165	COG3293	Transposase
BKD02_RS01220	COG1396	sequence-specific DNA binding
BKD02_RS01290	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKD02_RS01295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BKD02_RS01315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKD02_RS01315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKD02_RS01330	COG2989	Protein conserved in bacteria
BKD02_RS01350	COG0113	porphobilinogen synthase activity
BKD02_RS01365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKD02_RS01385	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BKD02_RS01395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BKD02_RS01410	COG1126	abc transporter atp-binding protein
BKD02_RS01415	COG0765	amino acid transport
BKD02_RS01420	COG4597	amino acid ABC transporter
BKD02_RS01430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD02_RS01440	COG0626	cystathionine gamma-synthase activity
BKD02_RS01515	COG2755	lipolytic protein G-D-S-L family
BKD02_RS01515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKD02_RS01715	COG3750	Belongs to the UPF0335 family
BKD02_RS01735	COG1620	l-lactate permease
BKD02_RS01740	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS01755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKD02_RS01770	COG0628	permease
BKD02_RS01785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKD02_RS01795	COG0243	molybdopterin cofactor binding
BKD02_RS01805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BKD02_RS01840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKD02_RS01845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKD02_RS01850	COG0314	molybdopterin synthase activity
BKD02_RS01870	COG0488	(ABC) transporter
BKD02_RS01905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BKD02_RS01910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD02_RS01915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BKD02_RS01925	COG0739	heme binding
BKD02_RS01935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKD02_RS01975	COG0494	nUDIX hydrolase
BKD02_RS01995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKD02_RS02005	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BKD02_RS02030	COG0681	Belongs to the peptidase S26 family
BKD02_RS02045	COG2207	Transcriptional regulator
BKD02_RS02050	COG2223	nitrite transmembrane transporter activity
BKD02_RS02055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD02_RS02060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKD02_RS02100	COG0741	lytic transglycosylase activity
BKD02_RS02105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKD02_RS02105	COG3743	rRNA binding
BKD02_RS02135	COG4974	Belongs to the 'phage' integrase family
BKD02_RS02140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKD02_RS02175	COG0625	glutathione transferase activity
BKD02_RS02180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKD02_RS02195	COG1573	uracil-dna glycosylase
BKD02_RS02210	COG0308	aminopeptidase N
BKD02_RS02215	COG2205	protein histidine kinase activity
BKD02_RS02215	COG2202	Pas domain
BKD02_RS02225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BKD02_RS02245	COG3088	subunit of a heme lyase
BKD02_RS02250	COG1138	Cytochrome C-type biogenesis protein
BKD02_RS02260	COG4235	cytochrome complex assembly
BKD02_RS02360	COG4695	Portal protein
BKD02_RS02375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKD02_RS02405	COG2205	protein histidine kinase activity
BKD02_RS02415	COG2166	iron-sulfur cluster assembly
BKD02_RS02430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKD02_RS02440	COG4957	zinc ion binding
BKD02_RS02460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKD02_RS02475	COG1376	ErfK ybiS ycfS ynhG family protein
BKD02_RS02480	COG0433	COG0433 Predicted ATPase
BKD02_RS02490	COG2807	transmembrane transport
BKD02_RS02495	COG2186	Transcriptional regulator
BKD02_RS02505	COG2336	PFAM SpoVT AbrB
BKD02_RS02515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKD02_RS02555	COG1070	Carbohydrate kinase
BKD02_RS02565	COG0673	inositol 2-dehydrogenase activity
BKD02_RS02575	COG1879	ABC-type sugar transport system periplasmic component
BKD02_RS02580	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD02_RS02585	COG1129	ABC transporter
BKD02_RS02690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKD02_RS02705	COG2351	hydroxyisourate hydrolase activity
BKD02_RS02715	COG1268	BioY protein
BKD02_RS02740	COG0574	Belongs to the PEP-utilizing enzyme family
BKD02_RS02740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKD02_RS02755	COG1196	nuclear chromosome segregation
BKD02_RS02775	COG1194	a g-specific adenine glycosylase
BKD02_RS02795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKD02_RS02805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BKD02_RS02825	COG0612	Peptidase, M16
BKD02_RS02830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKD02_RS02850	COG0678	peroxiredoxin activity
BKD02_RS02850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BKD02_RS02900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD02_RS02905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKD02_RS02915	COG0312	modulator of DNA gyrase
BKD02_RS02920	COG0194	GDP metabolic process
BKD02_RS02925	COG1561	YicC-like family, N-terminal region
BKD02_RS02935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKD02_RS02945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKD02_RS02970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKD02_RS03005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BKD02_RS03010	COG0305	Participates in initiation and elongation during chromosome replication
BKD02_RS03030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKD02_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS03040	COG1183	phosphatidylcholine synthase activity
BKD02_RS03050	COG5265	(ABC) transporter
BKD02_RS03080	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKD02_RS03090	COG1741	Belongs to the pirin family
BKD02_RS03115	COG1722	exodeoxyribonuclease VII activity
BKD02_RS03120	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKD02_RS03125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKD02_RS03125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKD02_RS03150	COG1278	Cold shock
BKD02_RS03165	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKD02_RS03170	COG0484	heat shock protein binding
BKD02_RS03185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BKD02_RS03200	COG1960	acyl-CoA dehydrogenase activity
BKD02_RS03235	COG0009	L-threonylcarbamoyladenylate synthase
BKD02_RS03240	COG0751	glycine-tRNA ligase activity
BKD02_RS03260	COG0142	geranyltranstransferase activity
BKD02_RS03365	COG3773	Cell wall hydrolase
BKD02_RS03390	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BKD02_RS03395	COG0477	Major facilitator Superfamily
BKD02_RS03405	COG1393	Belongs to the ArsC family
BKD02_RS03410	COG2169	Transcriptional regulator
BKD02_RS03410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKD02_RS03480	COG0402	S-adenosylhomocysteine deaminase activity
BKD02_RS03490	COG0583	DNA-binding transcription factor activity
BKD02_RS03500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKD02_RS03505	COG2080	2 iron, 2 sulfur cluster binding
BKD02_RS03515	COG3195	allantoin biosynthetic process
BKD02_RS03515	COG3648	Uricase
BKD02_RS03520	COG3257	ureidoglycine aminohydrolase activity
BKD02_RS03525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BKD02_RS03530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BKD02_RS03575	COG0019	diaminopimelate decarboxylase activity
BKD02_RS03610	COG3293	Transposase
BKD02_RS03625	COG1346	cytolysis
BKD02_RS03630	COG1380	Effector of murein hydrolase LrgA
BKD02_RS03635	COG0583	DNA-binding transcription factor activity
BKD02_RS03660	COG0156	8-amino-7-oxononanoate synthase activity
BKD02_RS03670	COG2205	protein histidine kinase activity
BKD02_RS03670	COG2198	Histidine kinase
BKD02_RS03670	COG0784	Response regulator, receiver
BKD02_RS03700	COG0534	Mate efflux family protein
BKD02_RS03720	COG0717	Belongs to the dCTP deaminase family
BKD02_RS03740	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKD02_RS03750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKD02_RS03765	COG5002	protein histidine kinase activity
BKD02_RS03770	COG2326	polyphosphate kinase activity
BKD02_RS03805	COG0318	PFAM AMP-dependent synthetase and ligase
BKD02_RS03835	COG0493	'glutamate synthase
BKD02_RS03845	COG0494	nUDIX hydrolase
BKD02_RS03850	COG1309	transcriptional regulator
BKD02_RS03870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD02_RS03875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD02_RS03880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD02_RS03885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD02_RS03890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD02_RS03900	COG4191	Histidine kinase
BKD02_RS03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKD02_RS04000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BKD02_RS04010	COG4453	Protein conserved in bacteria
BKD02_RS04015	COG3153	acetyltransferase
BKD02_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS04040	COG3254	rhamnose metabolic process
BKD02_RS04050	COG3842	ATPase activity
BKD02_RS04055	COG0395	ABC-type sugar transport system, permease component
BKD02_RS04060	COG1175	transmembrane transport
BKD02_RS04070	COG1414	Transcriptional regulator
BKD02_RS04085	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKD02_RS04085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKD02_RS04100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKD02_RS04110	COG1732	Glycine betaine
BKD02_RS04115	COG1174	glycine betaine transport
BKD02_RS04120	COG1125	glycine betaine transport
BKD02_RS04125	COG1174	glycine betaine transport
BKD02_RS04140	COG5001	Diguanylate cyclase
BKD02_RS04145	COG0351	phosphomethylpyrimidine kinase
BKD02_RS04170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKD02_RS04180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKD02_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
BKD02_RS04195	COG5265	(ABC) transporter
BKD02_RS04220	COG1012	belongs to the aldehyde dehydrogenase family
BKD02_RS04245	COG2197	response regulator
BKD02_RS04260	COG1218	3'(2'),5'-bisphosphate nucleotidase
BKD02_RS04280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD02_RS04285	COG2197	response regulator
BKD02_RS04310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKD02_RS04325	COG0175	sulfate reduction
BKD02_RS04330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKD02_RS04340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKD02_RS04340	COG1648	precorrin-2 dehydrogenase activity
BKD02_RS04350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKD02_RS04355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD02_RS04360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKD02_RS04385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKD02_RS04390	COG2860	membrane
BKD02_RS04395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD02_RS04425	COG0071	Belongs to the small heat shock protein (HSP20) family
BKD02_RS04435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKD02_RS04440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKD02_RS04450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKD02_RS04455	COG1137	ATPase activity
BKD02_RS04460	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BKD02_RS04470	COG0616	signal peptide processing
BKD02_RS04485	COG0116	Belongs to the methyltransferase superfamily
BKD02_RS04485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKD02_RS04490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKD02_RS04505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKD02_RS04510	COG0280	phosphate acetyltransferase
BKD02_RS04510	COG0281	malic enzyme
BKD02_RS04520	COG0728	peptidoglycan biosynthetic process
BKD02_RS04525	COG0180	Tryptophanyl-tRNA synthetase
BKD02_RS04535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BKD02_RS04540	COG1376	ErfK ybiS ycfS ynhG family protein
BKD02_RS04540	COG1388	LysM domain
BKD02_RS04550	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BKD02_RS04570	COG1643	Atp-dependent helicase
BKD02_RS04585	COG2153	protein acetylation
BKD02_RS04595	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BKD02_RS04610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKD02_RS04610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKD02_RS04620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKD02_RS04625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKD02_RS04640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BKD02_RS04645	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS04655	COG2226	methyltransferase
BKD02_RS04660	COG0384	phenazine biosynthesis protein PhzF
BKD02_RS04670	COG3459	Glycosyltransferase 36 associated
BKD02_RS04675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BKD02_RS04680	COG4208	sulfate ABC transporter
BKD02_RS04690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BKD02_RS04730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKD02_RS04740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKD02_RS04745	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKD02_RS04760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKD02_RS04790	COG3339	Conserved Protein
BKD02_RS04800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKD02_RS04805	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKD02_RS04820	COG4181	ATPase activity
BKD02_RS04830	COG0670	Belongs to the BI1 family
BKD02_RS04885	COG1272	protein, Hemolysin III
BKD02_RS04915	COG1072	(Pantothenic acid kinase))
BKD02_RS04920	COG1073	alpha beta
BKD02_RS04935	COG0033	Phosphoglucomutase
BKD02_RS04945	COG0346	lactoylglutathione lyase activity
BKD02_RS04970	COG1376	ErfK ybiS ycfS ynhG family protein
BKD02_RS04995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKD02_RS05000	COG1845	cytochrome c oxidase, subunit III
BKD02_RS05005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKD02_RS05010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKD02_RS05020	COG3474	cytochrome
BKD02_RS05030	COG1605	Chorismate mutase
BKD02_RS05030	COG0077	Prephenate dehydratase
BKD02_RS05035	COG2816	NAD+ diphosphatase activity
BKD02_RS05050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKD02_RS05065	COG2951	lytic endotransglycosylase activity
BKD02_RS05075	COG0583	DNA-binding transcription factor activity
BKD02_RS05080	COG2855	membrane
BKD02_RS05085	COG0539	negative regulation of cytoplasmic translation
BKD02_RS05130	COG0328	RNA-DNA hybrid ribonuclease activity
BKD02_RS05170	COG3617	BRO family, N-terminal domain
BKD02_RS05190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKD02_RS05195	COG1960	acyl-CoA dehydrogenase activity
BKD02_RS05200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKD02_RS05215	COG1024	Enoyl-CoA hydratase
BKD02_RS05245	COG4166	transmembrane transport
BKD02_RS05255	COG4174	ABC transporter (Permease)
BKD02_RS05260	COG4239	(ABC) transporter, permease
BKD02_RS05265	COG4172	Belongs to the ABC transporter superfamily
BKD02_RS05270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD02_RS05305	COG1024	Enoyl-CoA hydratase
BKD02_RS05320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKD02_RS05330	COG0791	NLP P60 protein
BKD02_RS05370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKD02_RS05375	COG2813	Specifically methylates the guanine in position
BKD02_RS05410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKD02_RS05410	COG0195	Participates in both transcription termination and antitermination
BKD02_RS05415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKD02_RS05420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKD02_RS05425	COG1396	sequence-specific DNA binding
BKD02_RS05460	COG0456	acetyltransferase
BKD02_RS05475	COG0783	Belongs to the Dps family
BKD02_RS05480	COG2309	aminopeptidase activity
BKD02_RS05490	COG3773	Cell wall hydrolase
BKD02_RS05495	COG0745	RESPONSE REGULATOR receiver
BKD02_RS05500	COG0704	Plays a role in the regulation of phosphate uptake
BKD02_RS05505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKD02_RS05515	COG0573	inorganic phosphate transmembrane transporter activity
BKD02_RS05520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKD02_RS05525	COG2832	Protein of unknown function (DUF454)
BKD02_RS05535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKD02_RS05545	COG0606	chelatase, subunit chli
BKD02_RS05555	COG3386	PFAM SMP-30 Gluconolaconase
BKD02_RS05570	COG3963	phosphatidate phosphatase activity
BKD02_RS05625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKD02_RS05635	COG3135	benzoate transporter
BKD02_RS05650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BKD02_RS05680	COG0285	dihydrofolate synthase activity
BKD02_RS05690	COG1074	ATP-dependent DNA helicase activity
BKD02_RS05695	COG2887	Belongs to the helicase family. UvrD subfamily
BKD02_RS05700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKD02_RS05705	COG3178	'Phosphotransferase
BKD02_RS05710	COG2205	protein histidine kinase activity
BKD02_RS05730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKD02_RS05735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKD02_RS05735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKD02_RS05750	COG2205	protein histidine kinase activity
BKD02_RS05755	COG0745	RESPONSE REGULATOR receiver
BKD02_RS05820	COG1396	sequence-specific DNA binding
BKD02_RS05825	COG2840	Smr protein MutS2
BKD02_RS05835	COG4395	Tim44
BKD02_RS05855	COG0237	dephospho-CoA kinase activity
BKD02_RS05885	COG1981	membrane
BKD02_RS05890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKD02_RS05895	COG1331	Highly conserved protein containing a thioredoxin domain
BKD02_RS05900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKD02_RS05935	COG1122	ATPase activity
BKD02_RS05940	COG4120	Belongs to the binding-protein-dependent transport system permease family
BKD02_RS05970	COG1609	Transcriptional regulator
BKD02_RS05985	COG1024	Enoyl-CoA hydratase
BKD02_RS05990	COG1012	belongs to the aldehyde dehydrogenase family
BKD02_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS06020	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS06030	COG1473	amidohydrolase
BKD02_RS06035	COG1686	Belongs to the peptidase S11 family
BKD02_RS06080	COG4536	flavin adenine dinucleotide binding
BKD02_RS06125	COG2217	Heavy metal translocating P-type atpase
BKD02_RS06130	COG0789	Transcriptional regulator
BKD02_RS06135	COG3293	Transposase
BKD02_RS06155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BKD02_RS06180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKD02_RS06200	COG2884	Cell division ATP-binding protein ftsE
BKD02_RS06220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BKD02_RS06250	COG0287	Prephenate dehydrogenase
BKD02_RS06260	COG2226	methyltransferase
BKD02_RS06295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKD02_RS06310	COG0300	oxidoreductase activity
BKD02_RS06325	COG0602	queuosine metabolic process
BKD02_RS06330	COG0720	synthase
BKD02_RS06340	COG2086	electron transfer activity
BKD02_RS06345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKD02_RS06355	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKD02_RS06380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD02_RS06385	COG1126	abc transporter atp-binding protein
BKD02_RS06390	COG0765	amino acid transport
BKD02_RS06395	COG0765	amino acid transport
BKD02_RS06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD02_RS06405	COG3608	succinylglutamate desuccinylase aspartoacylase
BKD02_RS06410	COG0006	proline dipeptidase activity
BKD02_RS06415	COG2423	ornithine cyclodeaminase activity
BKD02_RS06420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKD02_RS06425	COG1522	sequence-specific DNA binding
BKD02_RS06430	COG1012	belongs to the aldehyde dehydrogenase family
BKD02_RS06435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKD02_RS06445	COG0252	asparaginase activity
BKD02_RS06450	COG1802	Transcriptional regulator
BKD02_RS06455	COG0252	asparaginase activity
BKD02_RS06460	COG1126	abc transporter atp-binding protein
BKD02_RS06480	COG0765	amino acid transport
BKD02_RS06485	COG0765	amino acid transport
BKD02_RS06490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKD02_RS06515	COG2194	sulfuric ester hydrolase activity
BKD02_RS06540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD02_RS06555	COG0494	nUDIX hydrolase
BKD02_RS06580	COG0552	protein localization to endoplasmic reticulum
BKD02_RS06585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKD02_RS06605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BKD02_RS06625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKD02_RS06635	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD02_RS06645	COG1280	lysine exporter protein (LysE YggA)
BKD02_RS06700	COG1953	Uracil, thiamine, allantoin
BKD02_RS06755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKD02_RS06760	COG1946	Acyl-CoA thioesterase
BKD02_RS06765	COG0004	ammonium transporteR
BKD02_RS06775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD02_RS06780	COG0697	spore germination
BKD02_RS06850	COG1040	competence protein
BKD02_RS06860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKD02_RS06880	COG0527	aspartate kinase activity
BKD02_RS06895	COG2890	protein-(glutamine-N5) methyltransferase activity
BKD02_RS06920	COG1376	ErfK ybiS ycfS ynhG family protein
BKD02_RS06925	COG0739	heme binding
BKD02_RS06970	COG1061	Type III restriction enzyme res subunit
BKD02_RS06980	COG5433	transposase activity
BKD02_RS06985	COG0357	Ribosomal RNA small subunit methyltransferase G
BKD02_RS06990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKD02_RS07060	COG0799	negative regulation of ribosome biogenesis
BKD02_RS07080	COG0793	Belongs to the peptidase S41A family
BKD02_RS07100	COG0583	DNA-binding transcription factor activity
BKD02_RS07115	COG3293	Transposase
BKD02_RS07135	COG0288	reversible hydration of carbon dioxide
BKD02_RS07150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKD02_RS07155	COG0287	Prephenate dehydrogenase
BKD02_RS07155	COG1605	Chorismate mutase
BKD02_RS07170	COG1704	LemA family
BKD02_RS07175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BKD02_RS07190	COG2270	Major facilitator Superfamily
BKD02_RS07205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKD02_RS07205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKD02_RS07225	COG5425	PFAM Usg family protein
BKD02_RS07235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKD02_RS07350	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKD02_RS07355	COG0738	Major facilitator superfamily
BKD02_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS07370	COG0142	geranyltranstransferase activity
BKD02_RS07390	COG0183	Belongs to the thiolase family
BKD02_RS07415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BKD02_RS07420	COG1329	Transcriptional regulator
BKD02_RS07435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD02_RS07440	COG2258	MOSC domain
BKD02_RS07480	COG0488	(ABC) transporter
BKD02_RS07485	COG3750	Belongs to the UPF0335 family
BKD02_RS07500	COG0469	pyruvate kinase activity
BKD02_RS07505	COG0457	Tetratricopeptide repeat
BKD02_RS07515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKD02_RS07520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKD02_RS07550	COG0604	alcohol dehydrogenase
BKD02_RS07550	COG3321	synthase
BKD02_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS07625	COG1692	metallophosphoesterase
BKD02_RS07630	COG1253	flavin adenine dinucleotide binding
BKD02_RS07665	COG1132	(ABC) transporter
BKD02_RS07680	COG0483	inositol monophosphate 1-phosphatase activity
BKD02_RS07725	COG0824	Thioesterase
BKD02_RS07735	COG0848	biopolymer transport protein
BKD02_RS07755	COG2885	chlorophyll binding
BKD02_RS07770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKD02_RS07790	COG4974	Belongs to the 'phage' integrase family
BKD02_RS07805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD02_RS07815	COG0385	Bile acid
BKD02_RS07825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKD02_RS07845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD02_RS07850	COG0564	pseudouridine synthase activity
BKD02_RS08015	COG0784	Response regulator, receiver
BKD02_RS08030	COG3920	Histidine kinase
BKD02_RS08060	COG0848	biopolymer transport protein
BKD02_RS08075	COG4591	ABC-type transport system involved in lipoprotein release permease component
BKD02_RS08075	COG1136	(ABC) transporter
BKD02_RS08080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD02_RS08090	COG1522	sequence-specific DNA binding
BKD02_RS08110	COG0477	Major facilitator Superfamily
BKD02_RS08130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKD02_RS08135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKD02_RS08160	COG1012	belongs to the aldehyde dehydrogenase family
BKD02_RS08210	COG1129	ABC transporter
BKD02_RS08215	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD02_RS08220	COG1879	ABC-type sugar transport system periplasmic component
BKD02_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS08230	COG2376	Dihydroxyacetone kinase
BKD02_RS08235	COG1461	Dihydroxyacetone kinase
BKD02_RS08240	COG2390	Transcriptional regulator
BKD02_RS08245	COG2376	Dihydroxyacetone kinase
BKD02_RS08250	COG1461	Dihydroxyacetone kinase
BKD02_RS08265	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BKD02_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS08300	COG2224	Isocitrate lyase
BKD02_RS08320	COG3842	ATPase activity
BKD02_RS08325	COG1176	ABC-type spermidine putrescine transport system, permease component I
BKD02_RS08330	COG1177	transmembrane transport
BKD02_RS08345	COG2205	protein histidine kinase activity
BKD02_RS08470	COG1061	Type III restriction enzyme res subunit
BKD02_RS08560	COG0616	signal peptide processing
BKD02_RS08700	COG3179	chitinase
BKD02_RS08895	COG0747	negative chemotaxis
BKD02_RS08900	COG0601	transmembrane transport
BKD02_RS08905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKD02_RS08910	COG0444	Belongs to the ABC transporter superfamily
BKD02_RS08915	COG4608	Belongs to the ABC transporter superfamily
BKD02_RS08920	COG4175	Glycine betaine
BKD02_RS08925	COG4176	ABC-type proline glycine betaine transport system permease component
BKD02_RS08955	COG1522	sequence-specific DNA binding
BKD02_RS08965	COG0512	Glutamine amidotransferase of anthranilate synthase
BKD02_RS08965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKD02_RS08975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKD02_RS08990	COG1051	belongs to the nudix hydrolase family
BKD02_RS08995	COG3047	cAMP biosynthetic process
BKD02_RS09000	COG0435	Glutathione S-transferase
BKD02_RS09025	COG0714	Associated with various cellular activities
BKD02_RS09040	COG0617	tRNA 3'-terminal CCA addition
BKD02_RS09070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKD02_RS09075	COG1132	(ABC) transporter
BKD02_RS09095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKD02_RS09095	COG2857	Cytochrome c1
BKD02_RS09110	COG2030	dehydratase
BKD02_RS09135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKD02_RS09150	COG0006	proline dipeptidase activity
BKD02_RS09155	COG1496	oxidoreductase activity
BKD02_RS09190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKD02_RS09200	COG2205	protein histidine kinase activity
BKD02_RS09205	COG0745	RESPONSE REGULATOR receiver
BKD02_RS09210	COG1846	Transcriptional regulator
BKD02_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKD02_RS09245	COG1278	Cold shock
BKD02_RS09250	COG0739	heme binding
BKD02_RS09250	COG0741	lytic transglycosylase activity
BKD02_RS09250	COG1196	nuclear chromosome segregation
BKD02_RS09255	COG0556	nucleotide-excision repair
BKD02_RS09305	COG1522	sequence-specific DNA binding
BKD02_RS09315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKD02_RS09320	COG0492	ferredoxin-NADP+ reductase activity
BKD02_RS09325	COG0583	DNA-binding transcription factor activity
BKD02_RS09345	COG0625	glutathione transferase activity
BKD02_RS09350	COG1278	Cold shock
BKD02_RS09355	COG1136	(ABC) transporter
BKD02_RS09380	COG2321	neutral zinc metallopeptidase
BKD02_RS09400	COG0358	DNA primase activity
BKD02_RS09410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKD02_RS09430	COG2968	Membrane
BKD02_RS09470	COG1335	isochorismatase
BKD02_RS09475	COG2824	Alkylphosphonate utilization operon protein PhnA
BKD02_RS09480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKD02_RS09495	COG3293	Transposase
BKD02_RS09510	COG2267	carboxylic ester hydrolase activity
BKD02_RS09535	COG4106	trans-aconitate 2-methyltransferase activity
BKD02_RS09540	COG0477	Major facilitator Superfamily
BKD02_RS09550	COG0640	Transcriptional regulator
BKD02_RS09580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BKD02_RS09585	COG3023	N-Acetylmuramoyl-L-alanine amidase
BKD02_RS09600	COG1914	H( )-stimulated, divalent metal cation uptake system
BKD02_RS09675	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKD02_RS09680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKD02_RS09685	COG0849	cell division
BKD02_RS09690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKD02_RS09705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKD02_RS09725	COG0006	proline dipeptidase activity
BKD02_RS09735	COG1999	signal sequence binding
BKD02_RS09750	COG0210	DNA helicase
BKD02_RS09765	COG0277	FAD linked oxidase domain protein
BKD02_RS09795	COG2814	Major facilitator Superfamily
BKD02_RS09830	COG0330	HflC and HflK could
BKD02_RS09845	COG2081	HI0933 family
BKD02_RS09850	COG0560	Phosphoserine phosphatase
BKD02_RS09865	COG0028	Belongs to the TPP enzyme family
BKD02_RS09870	COG0440	acetolactate synthase activity
BKD02_RS09875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKD02_RS09890	COG3158	transport of potassium into the cell
BKD02_RS09905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKD02_RS09925	COG0384	phenazine biosynthesis protein PhzF
BKD02_RS09965	COG0310	cobalt ion transport
BKD02_RS09975	COG4413	Urea transporter
BKD02_RS10015	COG1649	PFAM Uncharacterised BCR, COG1649
BKD02_RS10030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD02_RS10035	COG1129	ABC transporter
BKD02_RS10035	COG0842	Transport permease protein
BKD02_RS10040	COG0842	Transport permease protein
BKD02_RS10055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKD02_RS10060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BKD02_RS10085	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKD02_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
BKD02_RS10100	COG4154	Belongs to the RbsD FucU family
BKD02_RS10120	COG0586	Pfam SNARE associated Golgi protein
BKD02_RS10125	COG1253	flavin adenine dinucleotide binding
BKD02_RS10135	COG4150	thiosulfate binding
BKD02_RS10140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BKD02_RS10145	COG4208	sulfate ABC transporter
BKD02_RS10160	COG4651	solute:proton antiporter activity
BKD02_RS10160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKD02_RS10175	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BKD02_RS10175	COG3264	Mechanosensitive ion channel
BKD02_RS10195	COG0583	DNA-binding transcription factor activity
BKD02_RS10320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD02_RS10370	COG0024	Methionine aminopeptidase
BKD02_RS10410	COG0436	Aminotransferase
BKD02_RS10420	COG1494	fructose-1,6-bisphosphatase
BKD02_RS10440	COG0346	lactoylglutathione lyase activity
BKD02_RS10495	COG0516	GMP reductase activity
BKD02_RS10495	COG0517	IMP dehydrogenase activity
BKD02_RS10500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKD02_RS10530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKD02_RS10620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKD02_RS10685	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKD02_RS10710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKD02_RS10735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKD02_RS10740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKD02_RS10750	COG2885	chlorophyll binding
BKD02_RS10765	COG1785	Belongs to the alkaline phosphatase family
BKD02_RS10770	COG0538	isocitrate dehydrogenase activity
BKD02_RS10780	COG0693	protein deglycase activity
BKD02_RS10785	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BKD02_RS10795	COG2358	TRAP transporter, solute receptor (TAXI family
BKD02_RS10810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKD02_RS10810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BKD02_RS10815	COG4770	biotin carboxylase activity
BKD02_RS10820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKD02_RS10825	COG1396	sequence-specific DNA binding
BKD02_RS10825	COG3800	Transcriptional regulator
BKD02_RS10870	COG1760	l-serine dehydratase
BKD02_RS10885	COG1686	Belongs to the peptidase S11 family
BKD02_RS10905	COG0537	adenosine 5'-monophosphoramidase activity
BKD02_RS10915	COG0584	glycerophosphoryl diester phosphodiesterase
BKD02_RS10970	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKD02_RS10995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BKD02_RS11000	COG0372	Belongs to the citrate synthase family
BKD02_RS11010	COG2333	competence protein COMEC
BKD02_RS11010	COG0658	competence protein
BKD02_RS11020	COG0303	'Molybdopterin
BKD02_RS11040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKD02_RS11090	COG0513	Belongs to the DEAD box helicase family
BKD02_RS11095	COG0316	Belongs to the HesB IscA family
BKD02_RS11115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD02_RS11145	COG2084	Dehydrogenase
BKD02_RS11150	COG0625	glutathione transferase activity
BKD02_RS11210	COG2989	Protein conserved in bacteria
BKD02_RS11310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD02_RS11315	COG1476	TRANSCRIPTIONal
BKD02_RS11340	COG1393	Belongs to the ArsC family
BKD02_RS11370	COG0084	hydrolase, TatD family'
BKD02_RS11405	COG0174	glutamine synthetase
BKD02_RS11410	COG0347	Belongs to the P(II) protein family
BKD02_RS11415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKD02_RS11415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKD02_RS11425	COG0546	phosphoglycolate phosphatase activity
BKD02_RS11445	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BKD02_RS11450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKD02_RS11470	COG0280	phosphate acetyltransferase
BKD02_RS11470	COG0281	malic enzyme
BKD02_RS11480	COG4948	Mandelate Racemase Muconate Lactonizing
BKD02_RS11485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BKD02_RS11495	COG1127	ABC transporter
BKD02_RS11525	COG0633	Ferredoxin
BKD02_RS11530	COG0492	ferredoxin-NADP+ reductase activity
BKD02_RS11540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKD02_RS11550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKD02_RS11565	COG3106	COG3106 Predicted ATPase
BKD02_RS11590	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BKD02_RS11600	COG0668	transmembrane transport
BKD02_RS11605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKD02_RS11635	COG3293	Transposase
BKD02_RS11645	COG1058	Belongs to the CinA family
BKD02_RS11645	COG1546	Belongs to the CinA family
BKD02_RS11665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKD02_RS11670	COG0513	Belongs to the DEAD box helicase family
BKD02_RS11675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKD02_RS11680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKD02_RS11685	COG2897	thiosulfate sulfurtransferase activity
BKD02_RS11700	COG0427	acetyl-CoA hydrolase
BKD02_RS11705	COG2814	Major facilitator Superfamily
BKD02_RS11720	COG0006	proline dipeptidase activity
BKD02_RS11725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKD02_RS11740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKD02_RS11750	COG3956	TIGRFAM MazG family protein
BKD02_RS11755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKD02_RS11775	COG1686	Belongs to the peptidase S11 family
BKD02_RS11800	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKD02_RS11840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKD02_RS11850	COG3617	BRO family, N-terminal domain
BKD02_RS11860	COG3617	BRO family, N-terminal domain
BKD02_RS11870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKD02_RS11875	COG1960	acyl-CoA dehydrogenase activity
BKD02_RS11880	COG0583	DNA-binding transcription factor activity
BKD02_RS11885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKD02_RS11890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKD02_RS11895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKD02_RS11930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKD02_RS11935	COG2095	MarC family integral membrane protein
BKD02_RS12060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKD02_RS12140	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKD02_RS12190	COG0396	ATPase activity
BKD02_RS12265	COG1530	ribonuclease E activity
BKD02_RS12540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BKD02_RS12635	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BKD02_RS12880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BKD02_RS13465	COG0243	molybdopterin cofactor binding
BKD02_RS13710	COG2223	nitrite transmembrane transporter activity
BKD02_RS13905	COG2205	protein histidine kinase activity
BKD02_RS13905	COG2202	Pas domain
BKD02_RS14215	COG2807	transmembrane transport
BKD02_RS14230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKD02_RS14475	COG1196	nuclear chromosome segregation
BKD02_RS14520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BKD02_RS14690	COG0305	Participates in initiation and elongation during chromosome replication
BKD02_RS14845	COG0151	Belongs to the GarS family
BKD02_RS14890	COG0277	FAD linked oxidase domain protein
BKD02_RS14905	COG0751	glycine-tRNA ligase activity
BKD02_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
BKD02_RS15920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKD02_RS15930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKD02_RS15960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKD02_RS16060	COG0281	malic enzyme
BKD02_RS16060	COG0280	phosphate acetyltransferase
BKD02_RS16225	COG3459	Glycosyltransferase 36 associated
BKD02_RS16330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKD02_RS16525	COG0033	Phosphoglucomutase
BKD02_RS16680	COG0583	DNA-binding transcription factor activity
BKD02_RS16845	COG4172	Belongs to the ABC transporter superfamily
BKD02_RS17290	COG2887	Belongs to the helicase family. UvrD subfamily
BKD02_RS17910	COG0765	amino acid transport
BKD02_RS17930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKD02_RS18200	COG0004	ammonium transporteR
BKD02_RS18225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs