locus-tag	class	description
IB024_RS00025	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS00375	COG0626	cystathionine gamma-synthase activity
IB024_RS00385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS00390	COG4597	amino acid ABC transporter
IB024_RS00395	COG0765	amino acid transport
IB024_RS00400	COG1126	abc transporter atp-binding protein
IB024_RS00415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IB024_RS00425	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IB024_RS00440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IB024_RS00455	COG0113	porphobilinogen synthase activity
IB024_RS00475	COG2989	Protein conserved in bacteria
IB024_RS00490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IB024_RS00490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IB024_RS00510	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IB024_RS00515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB024_RS00595	COG0010	Belongs to the arginase family
IB024_RS00640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IB024_RS00660	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IB024_RS00665	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IB024_RS00705	COG1007	ATP synthesis coupled electron transport
IB024_RS00720	COG0346	lactoylglutathione lyase activity
IB024_RS00780	COG1487	ribonuclease activity
IB024_RS00790	COG0483	inositol monophosphate 1-phosphatase activity
IB024_RS00795	COG2814	Major facilitator Superfamily
IB024_RS00830	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IB024_RS00855	COG2514	catechol 2,3-dioxygenase activity
IB024_RS00860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IB024_RS00880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IB024_RS00885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IB024_RS00890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IB024_RS00905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB024_RS00910	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IB024_RS00915	COG3454	Phosphonate metabolism
IB024_RS00920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IB024_RS00925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS00940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IB024_RS00965	COG1522	sequence-specific DNA binding
IB024_RS00970	COG1573	uracil-dna glycosylase
IB024_RS00995	COG0316	Belongs to the HesB IscA family
IB024_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
IB024_RS01020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IB024_RS01025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IB024_RS01035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IB024_RS01040	COG0805	protein transport
IB024_RS01055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IB024_RS01070	COG1862	Preprotein translocase
IB024_RS01115	COG0544	peptidyl-prolyl cis-trans isomerase activity
IB024_RS01135	COG4765	Protein conserved in bacteria
IB024_RS01155	COG0439	Biotin carboxylase
IB024_RS01160	COG0511	ligase activity, forming carbon-carbon bonds
IB024_RS01175	COG0501	Belongs to the peptidase M48B family
IB024_RS01180	COG0436	Aminotransferase
IB024_RS01185	COG1530	ribonuclease E activity
IB024_RS01195	COG0860	N-Acetylmuramoyl-L-alanine amidase
IB024_RS01200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IB024_RS01230	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IB024_RS01235	COG3657	addiction module killer protein
IB024_RS01410	COG2945	thiolester hydrolase activity
IB024_RS01420	COG0719	Fe-S assembly protein
IB024_RS01425	COG0396	ATPase activity
IB024_RS01430	COG0719	Fe-S assembly protein
IB024_RS01435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IB024_RS01440	COG2151	metal-sulfur cluster biosynthetic enzyme
IB024_RS01460	COG0513	Belongs to the DEAD box helicase family
IB024_RS01465	COG0316	Belongs to the HesB IscA family
IB024_RS01485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IB024_RS01510	COG2084	Dehydrogenase
IB024_RS01515	COG0625	glutathione transferase activity
IB024_RS01565	COG2989	Protein conserved in bacteria
IB024_RS01690	COG3750	Belongs to the UPF0335 family
IB024_RS01715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IB024_RS01720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IB024_RS01880	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IB024_RS01885	COG3657	addiction module killer protein
IB024_RS01945	COG1393	Belongs to the ArsC family
IB024_RS01975	COG0084	hydrolase, TatD family'
IB024_RS02000	COG0546	phosphoglycolate phosphatase activity
IB024_RS02010	COG0174	glutamine synthetase
IB024_RS02015	COG0347	Belongs to the P(II) protein family
IB024_RS02020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IB024_RS02020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IB024_RS02030	COG0546	phosphoglycolate phosphatase activity
IB024_RS02050	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IB024_RS02055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IB024_RS02075	COG0281	malic enzyme
IB024_RS02075	COG0280	phosphate acetyltransferase
IB024_RS02080	COG4948	Mandelate Racemase Muconate Lactonizing
IB024_RS02085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IB024_RS02090	COG1127	ABC transporter
IB024_RS02110	COG0633	Ferredoxin
IB024_RS02125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IB024_RS02135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IB024_RS02150	COG3106	COG3106 Predicted ATPase
IB024_RS02175	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
IB024_RS02185	COG0668	transmembrane transport
IB024_RS02190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IB024_RS02210	COG1546	Belongs to the CinA family
IB024_RS02210	COG1058	Belongs to the CinA family
IB024_RS02225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IB024_RS02230	COG0513	Belongs to the DEAD box helicase family
IB024_RS02235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IB024_RS02240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IB024_RS02245	COG2897	thiosulfate sulfurtransferase activity
IB024_RS02260	COG0427	acetyl-CoA hydrolase
IB024_RS02265	COG2814	Major facilitator Superfamily
IB024_RS02270	COG1566	PFAM secretion protein HlyD family protein
IB024_RS02280	COG0006	proline dipeptidase activity
IB024_RS02285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IB024_RS02295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IB024_RS02300	COG3956	TIGRFAM MazG family protein
IB024_RS02305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IB024_RS02325	COG1686	Belongs to the peptidase S11 family
IB024_RS02350	COG1752	Esterase of the alpha-beta hydrolase superfamily
IB024_RS02400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IB024_RS02405	COG1960	acyl-CoA dehydrogenase activity
IB024_RS02415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IB024_RS02420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB024_RS02425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB024_RS02465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IB024_RS02470	COG2095	MarC family integral membrane protein
IB024_RS02480	COG2188	Transcriptional regulator
IB024_RS02505	COG3547	Transposase (IS116 IS110 IS902 family)
IB024_RS02510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IB024_RS02535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IB024_RS02555	COG0569	domain protein
IB024_RS02560	COG2204	response regulator
IB024_RS02565	COG5000	phosphorelay sensor kinase activity
IB024_RS02570	COG2204	response regulator
IB024_RS02575	COG3852	Histidine kinase
IB024_RS02590	COG1546	Belongs to the CinA family
IB024_RS02590	COG1058	Belongs to the CinA family
IB024_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS02600	COG2867	negative regulation of translational initiation
IB024_RS02615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IB024_RS02620	COG0508	dehydrogenase complex catalyzes the overall conversion of
IB024_RS02625	COG0022	dehydrogenase e1 component
IB024_RS02625	COG0508	dehydrogenase complex catalyzes the overall conversion of
IB024_RS02630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IB024_RS02635	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IB024_RS02670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB024_RS02690	COG0303	'Molybdopterin
IB024_RS02700	COG0658	competence protein
IB024_RS02700	COG2333	competence protein COMEC
IB024_RS02710	COG0372	Belongs to the citrate synthase family
IB024_RS02715	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IB024_RS02740	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB024_RS02795	COG0584	glycerophosphoryl diester phosphodiesterase
IB024_RS02805	COG0537	adenosine 5'-monophosphoramidase activity
IB024_RS02820	COG1686	Belongs to the peptidase S11 family
IB024_RS02835	COG1760	l-serine dehydratase
IB024_RS02885	COG3800	Transcriptional regulator
IB024_RS02885	COG1396	sequence-specific DNA binding
IB024_RS02890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IB024_RS02895	COG4770	biotin carboxylase activity
IB024_RS02900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IB024_RS02900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IB024_RS02915	COG2358	TRAP transporter, solute receptor (TAXI family
IB024_RS02925	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IB024_RS02930	COG0693	protein deglycase activity
IB024_RS02940	COG0538	isocitrate dehydrogenase activity
IB024_RS02945	COG1785	Belongs to the alkaline phosphatase family
IB024_RS02960	COG2885	chlorophyll binding
IB024_RS02970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IB024_RS02975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IB024_RS02995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IB024_RS03020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IB024_RS03085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IB024_RS03175	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IB024_RS03200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IB024_RS03205	COG0517	IMP dehydrogenase activity
IB024_RS03205	COG0516	GMP reductase activity
IB024_RS03260	COG1494	fructose-1,6-bisphosphatase
IB024_RS03285	COG0346	lactoylglutathione lyase activity
IB024_RS03310	COG0436	Aminotransferase
IB024_RS03345	COG0024	Methionine aminopeptidase
IB024_RS03400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IB024_RS03520	COG0583	DNA-binding transcription factor activity
IB024_RS03540	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IB024_RS03540	COG3264	Mechanosensitive ion channel
IB024_RS03555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IB024_RS03555	COG4651	solute:proton antiporter activity
IB024_RS03570	COG4208	sulfate ABC transporter
IB024_RS03575	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IB024_RS03580	COG4150	thiosulfate binding
IB024_RS03590	COG1253	flavin adenine dinucleotide binding
IB024_RS03595	COG0586	Pfam SNARE associated Golgi protein
IB024_RS03615	COG4154	Belongs to the RbsD FucU family
IB024_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS03630	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB024_RS03645	COG1120	ATPase activity
IB024_RS03650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB024_RS03665	COG0842	Transport permease protein
IB024_RS03670	COG0842	Transport permease protein
IB024_RS03670	COG1129	ABC transporter
IB024_RS03675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB024_RS03680	COG1649	PFAM Uncharacterised BCR, COG1649
IB024_RS03720	COG4413	Urea transporter
IB024_RS03730	COG0310	cobalt ion transport
IB024_RS03770	COG0384	phenazine biosynthesis protein PhzF
IB024_RS03790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IB024_RS03810	COG3158	transport of potassium into the cell
IB024_RS03825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IB024_RS03830	COG0440	acetolactate synthase activity
IB024_RS03835	COG0028	Belongs to the TPP enzyme family
IB024_RS03845	COG0560	Phosphoserine phosphatase
IB024_RS03850	COG2081	HI0933 family
IB024_RS03865	COG0330	HflC and HflK could
IB024_RS03895	COG2814	Major facilitator Superfamily
IB024_RS03935	COG0277	FAD linked oxidase domain protein
IB024_RS03950	COG0210	DNA helicase
IB024_RS03965	COG1999	signal sequence binding
IB024_RS03975	COG0006	proline dipeptidase activity
IB024_RS03995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IB024_RS04005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IB024_RS04010	COG0849	cell division
IB024_RS04015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IB024_RS04020	COG1181	Belongs to the D-alanine--D-alanine ligase family
IB024_RS04080	COG1914	H( )-stimulated, divalent metal cation uptake system
IB024_RS04095	COG3023	N-Acetylmuramoyl-L-alanine amidase
IB024_RS04100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IB024_RS04130	COG0640	Transcriptional regulator
IB024_RS04140	COG0477	Major facilitator Superfamily
IB024_RS04160	COG2267	carboxylic ester hydrolase activity
IB024_RS04185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IB024_RS04190	COG2824	Alkylphosphonate utilization operon protein PhnA
IB024_RS04195	COG1335	isochorismatase
IB024_RS04210	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IB024_RS04230	COG2968	Membrane
IB024_RS04255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IB024_RS04260	COG0358	DNA primase activity
IB024_RS04280	COG2321	neutral zinc metallopeptidase
IB024_RS04295	COG1278	Cold shock
IB024_RS04300	COG0625	glutathione transferase activity
IB024_RS04305	COG0436	Aminotransferase
IB024_RS04320	COG0583	DNA-binding transcription factor activity
IB024_RS04325	COG0492	ferredoxin-NADP+ reductase activity
IB024_RS04330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IB024_RS04335	COG1522	sequence-specific DNA binding
IB024_RS04385	COG0556	nucleotide-excision repair
IB024_RS04395	COG1278	Cold shock
IB024_RS04405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IB024_RS04415	COG1846	Transcriptional regulator
IB024_RS04420	COG0745	RESPONSE REGULATOR receiver
IB024_RS04425	COG2205	protein histidine kinase activity
IB024_RS04435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IB024_RS04470	COG0006	proline dipeptidase activity
IB024_RS04480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IB024_RS04500	COG0012	GTP binding
IB024_RS04505	COG2030	dehydratase
IB024_RS04520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IB024_RS04520	COG2857	Cytochrome c1
IB024_RS04535	COG1132	(ABC) transporter
IB024_RS04540	COG1132	(ABC) transporter
IB024_RS04545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IB024_RS04560	COG3153	acetyltransferase
IB024_RS04570	COG0617	tRNA 3'-terminal CCA addition
IB024_RS04585	COG0714	Associated with various cellular activities
IB024_RS04610	COG0435	Glutathione S-transferase
IB024_RS04615	COG3047	cAMP biosynthetic process
IB024_RS04620	COG1051	belongs to the nudix hydrolase family
IB024_RS04660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IB024_RS04670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IB024_RS04670	COG0512	Glutamine amidotransferase of anthranilate synthase
IB024_RS04680	COG1522	sequence-specific DNA binding
IB024_RS04710	COG4176	ABC-type proline glycine betaine transport system permease component
IB024_RS04715	COG4175	Glycine betaine
IB024_RS04720	COG4608	Belongs to the ABC transporter superfamily
IB024_RS04725	COG0444	Belongs to the ABC transporter superfamily
IB024_RS04730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB024_RS04735	COG0601	transmembrane transport
IB024_RS04740	COG0747	negative chemotaxis
IB024_RS04935	COG2205	protein histidine kinase activity
IB024_RS04945	COG1177	transmembrane transport
IB024_RS04950	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB024_RS04955	COG3842	ATPase activity
IB024_RS04970	COG2224	Isocitrate lyase
IB024_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS05100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IB024_RS05180	COG1012	belongs to the aldehyde dehydrogenase family
IB024_RS05205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IB024_RS05225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IB024_RS05230	COG0564	pseudouridine synthase activity
IB024_RS05260	COG0784	Response regulator, receiver
IB024_RS05275	COG3920	Histidine kinase
IB024_RS05310	COG0848	biopolymer transport protein
IB024_RS05325	COG1136	(ABC) transporter
IB024_RS05325	COG4591	ABC-type transport system involved in lipoprotein release permease component
IB024_RS05330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB024_RS05340	COG1522	sequence-specific DNA binding
IB024_RS05360	COG0477	Major facilitator Superfamily
IB024_RS05380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IB024_RS05390	COG0385	Bile acid
IB024_RS05405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IB024_RS05420	COG2885	chlorophyll binding
IB024_RS05435	COG0848	biopolymer transport protein
IB024_RS05445	COG0824	Thioesterase
IB024_RS05490	COG0483	inositol monophosphate 1-phosphatase activity
IB024_RS05505	COG1132	(ABC) transporter
IB024_RS05535	COG1253	flavin adenine dinucleotide binding
IB024_RS05540	COG1692	metallophosphoesterase
IB024_RS05615	COG0604	alcohol dehydrogenase
IB024_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS05615	COG3321	synthase
IB024_RS05645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IB024_RS05650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IB024_RS05660	COG0457	Tetratricopeptide repeat
IB024_RS05665	COG0469	pyruvate kinase activity
IB024_RS05680	COG3750	Belongs to the UPF0335 family
IB024_RS05685	COG0488	(ABC) transporter
IB024_RS05720	COG2258	MOSC domain
IB024_RS05725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IB024_RS05740	COG1329	Transcriptional regulator
IB024_RS05745	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IB024_RS05760	COG0183	Belongs to the thiolase family
IB024_RS05780	COG0142	geranyltranstransferase activity
IB024_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS05795	COG0738	Major facilitator superfamily
IB024_RS05800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IB024_RS05915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IB024_RS05925	COG5425	PFAM Usg family protein
IB024_RS05945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IB024_RS05945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IB024_RS05960	COG2270	Major facilitator Superfamily
IB024_RS05975	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IB024_RS05980	COG1704	LemA family
IB024_RS05990	COG1605	Chorismate mutase
IB024_RS05990	COG0287	Prephenate dehydrogenase
IB024_RS05995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IB024_RS06005	COG0288	reversible hydration of carbon dioxide
IB024_RS06030	COG0583	DNA-binding transcription factor activity
IB024_RS06050	COG0793	Belongs to the peptidase S41A family
IB024_RS06070	COG0799	negative regulation of ribosome biogenesis
IB024_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS06165	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB024_RS06170	COG1129	ABC transporter
IB024_RS06180	COG0235	Class ii aldolase
IB024_RS06185	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS06210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IB024_RS06215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IB024_RS06325	COG0739	heme binding
IB024_RS06330	COG1376	ErfK ybiS ycfS ynhG family protein
IB024_RS06345	COG2890	protein-(glutamine-N5) methyltransferase activity
IB024_RS06360	COG0527	aspartate kinase activity
IB024_RS06390	COG1040	competence protein
IB024_RS06395	COG2226	methyltransferase
IB024_RS06450	COG2264	protein methyltransferase activity
IB024_RS06455	COG0697	spore germination
IB024_RS06460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IB024_RS06470	COG0004	ammonium transporteR
IB024_RS06475	COG1946	Acyl-CoA thioesterase
IB024_RS06480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IB024_RS06525	COG1953	Uracil, thiamine, allantoin
IB024_RS06565	COG1280	lysine exporter protein (LysE YggA)
IB024_RS06575	COG0508	dehydrogenase complex catalyzes the overall conversion of
IB024_RS06585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IB024_RS06605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IB024_RS06625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IB024_RS06630	COG0552	protein localization to endoplasmic reticulum
IB024_RS06655	COG0494	nUDIX hydrolase
IB024_RS06670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB024_RS06685	COG2194	sulfuric ester hydrolase activity
IB024_RS06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS06715	COG0765	amino acid transport
IB024_RS06720	COG0765	amino acid transport
IB024_RS06740	COG1126	abc transporter atp-binding protein
IB024_RS06750	COG1802	Transcriptional regulator
IB024_RS06755	COG0252	asparaginase activity
IB024_RS06765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IB024_RS06770	COG1012	belongs to the aldehyde dehydrogenase family
IB024_RS06775	COG1522	sequence-specific DNA binding
IB024_RS06780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IB024_RS06785	COG2423	ornithine cyclodeaminase activity
IB024_RS06790	COG0006	proline dipeptidase activity
IB024_RS06795	COG3608	succinylglutamate desuccinylase aspartoacylase
IB024_RS06800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS06805	COG0765	amino acid transport
IB024_RS06810	COG0765	amino acid transport
IB024_RS06815	COG1126	abc transporter atp-binding protein
IB024_RS06820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IB024_RS06905	COG1250	3-hydroxyacyl-CoA dehydrogenase
IB024_RS06910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IB024_RS06915	COG2086	electron transfer activity
IB024_RS06925	COG0720	synthase
IB024_RS06930	COG0602	queuosine metabolic process
IB024_RS06945	COG0300	oxidoreductase activity
IB024_RS06960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IB024_RS06990	COG2226	methyltransferase
IB024_RS07000	COG0287	Prephenate dehydrogenase
IB024_RS07030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IB024_RS07050	COG2884	Cell division ATP-binding protein ftsE
IB024_RS07065	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IB024_RS07090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IB024_RS07105	COG0789	Transcriptional regulator
IB024_RS07110	COG2217	Heavy metal translocating P-type atpase
IB024_RS07140	COG4536	flavin adenine dinucleotide binding
IB024_RS07180	COG0523	cobalamin synthesis protein
IB024_RS07185	COG1686	Belongs to the peptidase S11 family
IB024_RS07190	COG1473	amidohydrolase
IB024_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS07230	COG1012	belongs to the aldehyde dehydrogenase family
IB024_RS07235	COG1024	Enoyl-CoA hydratase
IB024_RS07250	COG1609	Transcriptional regulator
IB024_RS07260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IB024_RS07275	COG4120	Belongs to the binding-protein-dependent transport system permease family
IB024_RS07280	COG1122	ATPase activity
IB024_RS07320	COG1331	Highly conserved protein containing a thioredoxin domain
IB024_RS07325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IB024_RS07330	COG1981	membrane
IB024_RS07355	COG0237	dephospho-CoA kinase activity
IB024_RS07375	COG4395	Tim44
IB024_RS07385	COG2840	Smr protein MutS2
IB024_RS07390	COG1396	sequence-specific DNA binding
IB024_RS07455	COG0745	RESPONSE REGULATOR receiver
IB024_RS07460	COG2205	protein histidine kinase activity
IB024_RS07470	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB024_RS07470	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IB024_RS07475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB024_RS07485	COG2205	protein histidine kinase activity
IB024_RS07490	COG3178	'Phosphotransferase
IB024_RS07495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IB024_RS07500	COG2887	Belongs to the helicase family. UvrD subfamily
IB024_RS07505	COG1074	ATP-dependent DNA helicase activity
IB024_RS07515	COG0285	dihydrofolate synthase activity
IB024_RS07545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IB024_RS07560	COG3135	benzoate transporter
IB024_RS07570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IB024_RS07620	COG3963	phosphatidate phosphatase activity
IB024_RS07635	COG3386	PFAM SMP-30 Gluconolaconase
IB024_RS07645	COG0606	chelatase, subunit chli
IB024_RS07655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IB024_RS07660	COG2832	Protein of unknown function (DUF454)
IB024_RS07665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IB024_RS07670	COG0573	inorganic phosphate transmembrane transporter activity
IB024_RS07680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IB024_RS07685	COG0704	Plays a role in the regulation of phosphate uptake
IB024_RS07690	COG0745	RESPONSE REGULATOR receiver
IB024_RS07695	COG3773	Cell wall hydrolase
IB024_RS07705	COG2309	aminopeptidase activity
IB024_RS07710	COG0783	Belongs to the Dps family
IB024_RS07720	COG0456	acetyltransferase
IB024_RS07755	COG1396	sequence-specific DNA binding
IB024_RS07760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IB024_RS07765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IB024_RS07775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IB024_RS07775	COG0195	Participates in both transcription termination and antitermination
IB024_RS07815	COG2813	Specifically methylates the guanine in position
IB024_RS07820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IB024_RS07860	COG0791	NLP P60 protein
IB024_RS07870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IB024_RS07885	COG1024	Enoyl-CoA hydratase
IB024_RS07920	COG4172	Belongs to the ABC transporter superfamily
IB024_RS07925	COG4239	(ABC) transporter, permease
IB024_RS07930	COG4174	ABC transporter (Permease)
IB024_RS07940	COG4166	transmembrane transport
IB024_RS07960	COG1024	Enoyl-CoA hydratase
IB024_RS07975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IB024_RS07980	COG1960	acyl-CoA dehydrogenase activity
IB024_RS07985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IB024_RS08025	COG0539	negative regulation of cytoplasmic translation
IB024_RS08030	COG2855	membrane
IB024_RS08035	COG0583	DNA-binding transcription factor activity
IB024_RS08040	COG2951	lytic endotransglycosylase activity
IB024_RS08055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IB024_RS08070	COG2816	NAD+ diphosphatase activity
IB024_RS08075	COG0077	Prephenate dehydratase
IB024_RS08075	COG1605	Chorismate mutase
IB024_RS08085	COG3474	cytochrome
IB024_RS08095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IB024_RS08100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IB024_RS08105	COG1845	cytochrome c oxidase, subunit III
IB024_RS08110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IB024_RS08130	COG1376	ErfK ybiS ycfS ynhG family protein
IB024_RS08160	COG0346	lactoylglutathione lyase activity
IB024_RS08165	COG0489	protein tyrosine kinase activity
IB024_RS08170	COG0033	Phosphoglucomutase
IB024_RS08180	COG1073	alpha beta
IB024_RS08185	COG1072	(Pantothenic acid kinase))
IB024_RS08215	COG1272	protein, Hemolysin III
IB024_RS08280	COG3339	Conserved Protein
IB024_RS08285	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IB024_RS08290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IB024_RS08300	COG4181	ATPase activity
IB024_RS08310	COG0670	Belongs to the BI1 family
IB024_RS08330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IB024_RS08340	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IB024_RS08345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IB024_RS08355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IB024_RS08400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IB024_RS08410	COG4208	sulfate ABC transporter
IB024_RS08415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IB024_RS08420	COG3459	Glycosyltransferase 36 associated
IB024_RS08430	COG0384	phenazine biosynthesis protein PhzF
IB024_RS08440	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS08445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IB024_RS08460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IB024_RS08465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IB024_RS08470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IB024_RS08470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IB024_RS08485	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IB024_RS08495	COG2153	protein acetylation
IB024_RS08510	COG1643	Atp-dependent helicase
IB024_RS08525	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IB024_RS08535	COG1376	ErfK ybiS ycfS ynhG family protein
IB024_RS08535	COG1388	LysM domain
IB024_RS08540	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IB024_RS08550	COG0180	Tryptophanyl-tRNA synthetase
IB024_RS08555	COG0728	peptidoglycan biosynthetic process
IB024_RS08570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IB024_RS08585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IB024_RS08590	COG0116	Belongs to the methyltransferase superfamily
IB024_RS08590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IB024_RS08605	COG0616	signal peptide processing
IB024_RS08615	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IB024_RS08620	COG1137	ATPase activity
IB024_RS08625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IB024_RS08635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IB024_RS08640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IB024_RS08650	COG0071	Belongs to the small heat shock protein (HSP20) family
IB024_RS08675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB024_RS08705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IB024_RS08710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IB024_RS08715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IB024_RS08725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IB024_RS08725	COG1648	precorrin-2 dehydrogenase activity
IB024_RS08735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IB024_RS08740	COG0175	sulfate reduction
IB024_RS08755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IB024_RS08775	COG2197	response regulator
IB024_RS08780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IB024_RS08795	COG1218	3'(2'),5'-bisphosphate nucleotidase
IB024_RS08810	COG2197	response regulator
IB024_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
IB024_RS08850	COG5265	(ABC) transporter
IB024_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
IB024_RS08860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IB024_RS08865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IB024_RS08870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IB024_RS08895	COG0351	phosphomethylpyrimidine kinase
IB024_RS08900	COG5001	Diguanylate cyclase
IB024_RS08910	COG0789	Transcriptional regulator
IB024_RS08915	COG1174	glycine betaine transport
IB024_RS08920	COG1125	glycine betaine transport
IB024_RS08925	COG1174	glycine betaine transport
IB024_RS08930	COG1732	Glycine betaine
IB024_RS08940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IB024_RS08955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IB024_RS08955	COG0446	pyridine nucleotide-disulphide oxidoreductase
IB024_RS08970	COG1414	Transcriptional regulator
IB024_RS08980	COG1175	transmembrane transport
IB024_RS08985	COG0395	ABC-type sugar transport system, permease component
IB024_RS08990	COG3842	ATPase activity
IB024_RS08995	COG4948	Mandelate Racemase Muconate Lactonizing
IB024_RS09000	COG3254	rhamnose metabolic process
IB024_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS09020	COG4948	Mandelate Racemase Muconate Lactonizing
IB024_RS09025	COG3153	acetyltransferase
IB024_RS09030	COG4453	Protein conserved in bacteria
IB024_RS09040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IB024_RS09055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IB024_RS09095	COG3012	SEC-C Motif Domain Protein
IB024_RS09095	COG3318	Belongs to the UPF0149 family
IB024_RS09175	COG4191	Histidine kinase
IB024_RS09180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB024_RS09185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IB024_RS09200	COG1309	transcriptional regulator
IB024_RS09205	COG0494	nUDIX hydrolase
IB024_RS09215	COG0493	'glutamate synthase
IB024_RS09245	COG0318	PFAM AMP-dependent synthetase and ligase
IB024_RS09270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS09280	COG2326	polyphosphate kinase activity
IB024_RS09285	COG5002	protein histidine kinase activity
IB024_RS09300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IB024_RS09310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IB024_RS09330	COG0717	Belongs to the dCTP deaminase family
IB024_RS09345	COG2340	Cysteine-rich secretory protein family
IB024_RS09350	COG0534	Mate efflux family protein
IB024_RS09380	COG2198	Histidine kinase
IB024_RS09380	COG2205	protein histidine kinase activity
IB024_RS09380	COG0784	Response regulator, receiver
IB024_RS09390	COG0156	8-amino-7-oxononanoate synthase activity
IB024_RS09415	COG0583	DNA-binding transcription factor activity
IB024_RS09420	COG1380	Effector of murein hydrolase LrgA
IB024_RS09425	COG1346	cytolysis
IB024_RS09455	COG0019	diaminopimelate decarboxylase activity
IB024_RS09495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IB024_RS09500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IB024_RS09505	COG3257	ureidoglycine aminohydrolase activity
IB024_RS09510	COG3648	Uricase
IB024_RS09510	COG3195	allantoin biosynthetic process
IB024_RS09520	COG2080	2 iron, 2 sulfur cluster binding
IB024_RS09525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IB024_RS09535	COG0583	DNA-binding transcription factor activity
IB024_RS09545	COG0402	S-adenosylhomocysteine deaminase activity
IB024_RS09605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IB024_RS09605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IB024_RS09615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IB024_RS09615	COG2169	Transcriptional regulator
IB024_RS09620	COG1393	Belongs to the ArsC family
IB024_RS09630	COG0477	Major facilitator Superfamily
IB024_RS09635	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IB024_RS09660	COG3773	Cell wall hydrolase
IB024_RS09755	COG0142	geranyltranstransferase activity
IB024_RS09770	COG0751	glycine-tRNA ligase activity
IB024_RS09775	COG0009	L-threonylcarbamoyladenylate synthase
IB024_RS09805	COG1960	acyl-CoA dehydrogenase activity
IB024_RS09820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IB024_RS09840	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IB024_RS09850	COG1278	Cold shock
IB024_RS09880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IB024_RS09880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IB024_RS09885	COG0123	including yeast histone deacetylase and acetoin utilization protein
IB024_RS09890	COG1722	exodeoxyribonuclease VII activity
IB024_RS09910	COG1741	Belongs to the pirin family
IB024_RS09920	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IB024_RS09945	COG5265	(ABC) transporter
IB024_RS09955	COG1183	phosphatidylcholine synthase activity
IB024_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS09965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IB024_RS09980	COG0305	Participates in initiation and elongation during chromosome replication
IB024_RS09985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IB024_RS10010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IB024_RS10025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IB024_RS10030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IB024_RS10035	COG1561	YicC-like family, N-terminal region
IB024_RS10040	COG0194	GDP metabolic process
IB024_RS10045	COG0312	modulator of DNA gyrase
IB024_RS10055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IB024_RS10060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IB024_RS10110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IB024_RS10110	COG0678	peroxiredoxin activity
IB024_RS10130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IB024_RS10135	COG0612	Peptidase, M16
IB024_RS10150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IB024_RS10160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IB024_RS10180	COG1194	a g-specific adenine glycosylase
IB024_RS10200	COG1196	nuclear chromosome segregation
IB024_RS10215	COG0574	Belongs to the PEP-utilizing enzyme family
IB024_RS10215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IB024_RS10240	COG1268	BioY protein
IB024_RS10250	COG2351	hydroxyisourate hydrolase activity
IB024_RS10265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IB024_RS10335	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IB024_RS10335	COG0662	Cupin 2, conserved barrel domain protein
IB024_RS10340	COG2942	2-epimerase
IB024_RS10345	COG0438	transferase activity, transferring glycosyl groups
IB024_RS10345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IB024_RS10355	COG1129	ABC transporter
IB024_RS10360	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB024_RS10365	COG1879	ABC-type sugar transport system periplasmic component
IB024_RS10375	COG0673	inositol 2-dehydrogenase activity
IB024_RS10385	COG1070	Carbohydrate kinase
IB024_RS10420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IB024_RS10430	COG2336	PFAM SpoVT AbrB
IB024_RS10440	COG2186	Transcriptional regulator
IB024_RS10445	COG2807	transmembrane transport
IB024_RS10455	COG0433	COG0433 Predicted ATPase
IB024_RS10460	COG1376	ErfK ybiS ycfS ynhG family protein
IB024_RS10475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IB024_RS10490	COG4957	zinc ion binding
IB024_RS10500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IB024_RS10510	COG0154	amidase activity
IB024_RS10515	COG2166	iron-sulfur cluster assembly
IB024_RS10525	COG2205	protein histidine kinase activity
IB024_RS10555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IB024_RS10570	COG4695	Portal protein
IB024_RS10680	COG4235	cytochrome complex assembly
IB024_RS10690	COG1138	Cytochrome C-type biogenesis protein
IB024_RS10695	COG3088	subunit of a heme lyase
IB024_RS10715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IB024_RS10725	COG2202	Pas domain
IB024_RS10725	COG2205	protein histidine kinase activity
IB024_RS10730	COG0308	aminopeptidase N
IB024_RS10745	COG1573	uracil-dna glycosylase
IB024_RS10765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IB024_RS10775	COG0625	glutathione transferase activity
IB024_RS10810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IB024_RS10815	COG4974	Belongs to the 'phage' integrase family
IB024_RS10845	COG3743	rRNA binding
IB024_RS10845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IB024_RS10850	COG0741	lytic transglycosylase activity
IB024_RS10890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IB024_RS10895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IB024_RS10900	COG2223	nitrite transmembrane transporter activity
IB024_RS10905	COG2207	Transcriptional regulator
IB024_RS10920	COG0681	Belongs to the peptidase S26 family
IB024_RS10945	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IB024_RS10955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IB024_RS10975	COG0494	nUDIX hydrolase
IB024_RS11000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IB024_RS11010	COG0739	heme binding
IB024_RS11025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IB024_RS11030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB024_RS11035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IB024_RS11065	COG0488	(ABC) transporter
IB024_RS11085	COG0314	molybdopterin synthase activity
IB024_RS11090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IB024_RS11095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IB024_RS11130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IB024_RS11140	COG0243	molybdopterin cofactor binding
IB024_RS11150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IB024_RS11160	COG1192	Involved in chromosome partitioning
IB024_RS11170	COG1414	Transcriptional regulator
IB024_RS11185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB024_RS11190	COG1957	nucleoside hydrolase
IB024_RS11195	COG1079	Belongs to the binding-protein-dependent transport system permease family
IB024_RS11205	COG3845	ABC transporter
IB024_RS11210	COG1744	ABC transporter substrate-binding protein PnrA-like
IB024_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS11230	COG1535	isochorismatase
IB024_RS11230	COG3433	isochorismatase activity
IB024_RS11235	COG1021	2,3-dihydroxybenzoate-AMP ligase
IB024_RS11240	COG1169	isochorismate synthase
IB024_RS11245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IB024_RS11245	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IB024_RS11250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IB024_RS11270	COG4944	Protein of unknown function (DUF1109)
IB024_RS11275	COG2186	Transcriptional regulator
IB024_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS11320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IB024_RS11325	COG0508	dehydrogenase complex catalyzes the overall conversion of
IB024_RS11330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IB024_RS11360	COG4191	Histidine kinase
IB024_RS11365	COG4566	intracellular signal transduction
IB024_RS11375	COG0827	DNA restriction-modification system
IB024_RS11380	COG0827	DNA restriction-modification system
IB024_RS11400	COG0483	inositol monophosphate 1-phosphatase activity
IB024_RS11415	COG0071	Belongs to the small heat shock protein (HSP20) family
IB024_RS11430	COG0069	glutamate synthase activity
IB024_RS11430	COG0070	glutamate synthase
IB024_RS11430	COG0067	glutamate synthase
IB024_RS11440	COG1113	amino acid transport
IB024_RS11460	COG2948	multi-organism process
IB024_RS11510	COG2951	lytic endotransglycosylase activity
IB024_RS11515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IB024_RS11535	COG0330	HflC and HflK could
IB024_RS11550	COG5310	Homospermidine synthase
IB024_RS11570	COG2204	response regulator
IB024_RS11575	COG3108	Peptidase M15
IB024_RS11580	COG0800	Aldolase
IB024_RS11595	COG0725	ABC transporter, periplasmic molybdate-binding protein
IB024_RS11600	COG4149	molybdate abc transporter
IB024_RS11605	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IB024_RS11625	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IB024_RS11635	COG0583	DNA-binding transcription factor activity
IB024_RS11640	COG0154	amidase activity
IB024_RS11685	COG0673	inositol 2-dehydrogenase activity
IB024_RS11730	COG1309	transcriptional regulator
IB024_RS11745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IB024_RS11750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IB024_RS11755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IB024_RS11770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IB024_RS11780	COG4786	Flagellar basal body rod
IB024_RS11785	COG1157	protein secretion by the type III secretion system
IB024_RS11795	COG0671	phosphoesterase, PA-phosphatase related
IB024_RS11805	COG0463	Glycosyl transferase, family 2
IB024_RS11825	COG2963	transposase activity
IB024_RS11830	COG2271	Major facilitator Superfamily
IB024_RS11835	COG0235	Class ii aldolase
IB024_RS11840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IB024_RS11845	COG1349	DNA-binding transcription factor activity
IB024_RS11850	COG3622	Belongs to the hyi family
IB024_RS11855	COG3395	kinase activity
IB024_RS11860	COG2084	Dehydrogenase
IB024_RS11865	COG1815	bacterial-type flagellum-dependent cell motility
IB024_RS11870	COG1558	bacterial-type flagellum-dependent cell motility
IB024_RS11875	COG1677	Flagellar hook-basal body complex protein FliE
IB024_RS11880	COG4786	Flagellar basal body rod
IB024_RS11885	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IB024_RS11890	COG1706	bacterial-type flagellum-dependent cell motility
IB024_RS11910	COG1338	Plays a role in the flagellum-specific transport system
IB024_RS11925	COG0583	DNA-binding transcription factor activity
IB024_RS11935	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IB024_RS11955	COG3038	cytochrome b561
IB024_RS11990	COG2186	Transcriptional regulator
IB024_RS11995	COG0583	DNA-binding transcription factor activity
IB024_RS12000	COG0277	FAD linked oxidase domain protein
IB024_RS12010	COG0247	lactate metabolic process
IB024_RS12020	COG0656	L-ascorbic acid biosynthetic process
IB024_RS12025	COG1376	ErfK ybiS ycfS ynhG family protein
IB024_RS12025	COG1388	LysM domain
IB024_RS12030	COG2818	Glycosylase
IB024_RS12060	COG2259	Doxx family
IB024_RS12090	COG0196	riboflavin kinase activity
IB024_RS12115	COG0590	tRNA wobble adenosine to inosine editing
IB024_RS12125	COG0742	ribosomal rna small subunit methyltransferase
IB024_RS12130	COG0612	Peptidase, M16
IB024_RS12135	COG0612	Peptidase, M16
IB024_RS12145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IB024_RS12145	COG0475	glutathione-regulated potassium exporter activity
IB024_RS12150	COG0312	modulator of DNA gyrase
IB024_RS12170	COG1519	Transferase
IB024_RS12190	COG2814	Major facilitator Superfamily
IB024_RS12195	COG1960	acyl-CoA dehydrogenase activity
IB024_RS12205	COG1024	Enoyl-CoA hydratase
IB024_RS12210	COG1250	3-hydroxyacyl-CoA dehydrogenase
IB024_RS12215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IB024_RS12255	COG1477	protein flavinylation
IB024_RS12275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IB024_RS12280	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IB024_RS12300	COG1845	cytochrome c oxidase, subunit III
IB024_RS12315	COG3256	nitric oxide reductase
IB024_RS12320	COG0714	Associated with various cellular activities
IB024_RS12345	COG2151	metal-sulfur cluster biosynthetic enzyme
IB024_RS12395	COG4214	carbohydrate transport
IB024_RS12405	COG1069	ribulokinase activity
IB024_RS12410	COG5654	RES domain protein
IB024_RS12420	COG4178	(ABC) transporter
IB024_RS12460	COG1477	protein flavinylation
IB024_RS12485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IB024_RS12500	COG0826	peptidase U32
IB024_RS12525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IB024_RS12530	COG2181	nitrate reductase activity
IB024_RS12535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IB024_RS12540	COG1140	nitrate reductase beta subunit
IB024_RS12545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IB024_RS12550	COG2223	nitrite transmembrane transporter activity
IB024_RS12560	COG1609	Transcriptional regulator
IB024_RS12565	COG1653	transport
IB024_RS12590	COG0673	inositol 2-dehydrogenase activity
IB024_RS12595	COG2814	Major facilitator Superfamily
IB024_RS12600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IB024_RS12625	COG2894	cell division
IB024_RS12655	COG3842	ATPase activity
IB024_RS12660	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB024_RS12665	COG1177	transmembrane transport
IB024_RS12700	COG0076	glutamate decarboxylase activity
IB024_RS12705	COG0531	amino acid
IB024_RS12725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IB024_RS12740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IB024_RS12745	COG3191	aminopeptidase activity
IB024_RS12760	COG3258	Cytochrome c
IB024_RS12765	COG0583	DNA-binding transcription factor activity
IB024_RS12770	COG0753	catalase activity
IB024_RS12785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IB024_RS12785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IB024_RS12825	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IB024_RS12830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IB024_RS12835	COG2124	cytochrome p450
IB024_RS12865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IB024_RS12885	COG2186	Transcriptional regulator
IB024_RS12890	COG1940	carbohydrate kinase activity
IB024_RS12890	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IB024_RS12910	COG2197	response regulator
IB024_RS12925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IB024_RS12930	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IB024_RS12950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IB024_RS12960	COG0110	maltose O-acetyltransferase activity
IB024_RS12980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IB024_RS13000	COG0438	transferase activity, transferring glycosyl groups
IB024_RS13015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IB024_RS13020	COG4310	Domain of unknown function (DUF2172)
IB024_RS13025	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IB024_RS13040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IB024_RS13045	COG2233	PERMEase
IB024_RS13055	COG2814	Major facilitator Superfamily
IB024_RS13060	COG0583	DNA-binding transcription factor activity
IB024_RS13065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IB024_RS13070	COG1960	acyl-CoA dehydrogenase activity
IB024_RS13075	COG0183	Belongs to the thiolase family
IB024_RS13085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IB024_RS13095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IB024_RS13100	COG0242	peptide deformylase activity
IB024_RS13105	COG2354	Protein conserved in bacteria
IB024_RS13110	COG0640	Transcriptional regulator
IB024_RS13145	COG1131	(ABC) transporter
IB024_RS13150	COG0842	Transport permease protein
IB024_RS13160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IB024_RS13215	COG1252	NADH dehydrogenase
IB024_RS13230	COG1115	amino acid carrier protein
IB024_RS13245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IB024_RS13250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IB024_RS13260	COG0156	8-amino-7-oxononanoate synthase activity
IB024_RS13275	COG0521	Mo-molybdopterin cofactor biosynthetic process
IB024_RS13290	COG2111	Na H antiporter
IB024_RS13290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IB024_RS13295	COG1006	Multisubunit Na H antiporter MnhC subunit
IB024_RS13300	COG0651	ATP synthesis coupled electron transport
IB024_RS13305	COG1863	multisubunit Na H antiporter MnhE subunit
IB024_RS13310	COG2212	antiporter activity
IB024_RS13325	COG4988	ABC transporter
IB024_RS13330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IB024_RS13335	COG1271	oxidase subunit
IB024_RS13340	COG1294	oxidase, subunit
IB024_RS13350	COG2188	Transcriptional regulator
IB024_RS13355	COG2971	BadF BadG BcrA BcrD
IB024_RS13370	COG1175	transmembrane transport
IB024_RS13375	COG0395	ABC-type sugar transport system, permease component
IB024_RS13380	COG0673	inositol 2-dehydrogenase activity
IB024_RS13400	COG0022	dehydrogenase e1 component
IB024_RS13435	COG0477	Major facilitator Superfamily
IB024_RS13440	COG3145	DNA-N1-methyladenine dioxygenase activity
IB024_RS13445	COG4172	Belongs to the ABC transporter superfamily
IB024_RS13450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB024_RS13455	COG0601	transmembrane transport
IB024_RS13510	COG1228	amidohydrolase
IB024_RS13535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB024_RS13540	COG0444	Belongs to the ABC transporter superfamily
IB024_RS13565	COG2819	hydrolase of the alpha beta superfamily
IB024_RS13585	COG4592	Periplasmic binding protein
IB024_RS13590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB024_RS13595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB024_RS13600	COG1120	ATPase activity
IB024_RS13725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IB024_RS13730	COG1959	2 iron, 2 sulfur cluster binding
IB024_RS13765	COG4603	Belongs to the binding-protein-dependent transport system permease family
IB024_RS13770	COG3845	ABC transporter
IB024_RS13780	COG1183	phosphatidylcholine synthase activity
IB024_RS13785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IB024_RS13810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IB024_RS13815	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IB024_RS13835	COG0785	Cytochrome C biogenesis protein
IB024_RS13870	COG0697	spore germination
IB024_RS13875	COG0187	DNA topoisomerase II activity
IB024_RS13910	COG1960	acyl-CoA dehydrogenase activity
IB024_RS13920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IB024_RS13930	COG0758	DNA mediated transformation
IB024_RS13940	COG1754	DNA topoisomerase type I activity
IB024_RS13940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IB024_RS13945	COG0557	exoribonuclease II activity
IB024_RS13985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IB024_RS13990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IB024_RS14055	COG2176	DNA-directed DNA polymerase activity
IB024_RS14075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IB024_RS14080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS14110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IB024_RS14120	COG1414	Transcriptional regulator
IB024_RS14135	COG0583	DNA-binding transcription factor activity
IB024_RS14140	COG2267	carboxylic ester hydrolase activity
IB024_RS14145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IB024_RS14150	COG3485	protocatechuate 3,4-dioxygenase
IB024_RS14155	COG3485	protocatechuate 3,4-dioxygenase
IB024_RS14160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IB024_RS14165	COG0683	leucine binding
IB024_RS14185	COG3842	ATPase activity
IB024_RS14210	COG0395	ABC-type sugar transport system, permease component
IB024_RS14220	COG0471	metal ion transport
IB024_RS14220	COG3273	potassium ion transport
IB024_RS14230	COG2252	PERMEase
IB024_RS14255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IB024_RS14280	COG4607	ABC-type enterochelin transport system periplasmic component
IB024_RS14285	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB024_RS14290	COG4605	iron ion homeostasis
IB024_RS14295	COG4604	ABC transporter, ATP-binding protein
IB024_RS14310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS14315	COG0765	amino acid transport
IB024_RS14320	COG1126	abc transporter atp-binding protein
IB024_RS14325	COG0248	Ppx GppA phosphatase
IB024_RS14335	COG0477	Major facilitator Superfamily
IB024_RS14340	COG3842	ATPase activity
IB024_RS14345	COG0395	ABC-type sugar transport system, permease component
IB024_RS14350	COG1175	transmembrane transport
IB024_RS14390	COG1840	ABC-type Fe3 transport system, periplasmic component
IB024_RS14395	COG3842	ATPase activity
IB024_RS14400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IB024_RS14410	COG2132	Multicopper oxidase
IB024_RS14420	COG0477	Major facilitator Superfamily
IB024_RS14430	COG0450	alkyl hydroperoxide reductase
IB024_RS14445	COG0673	inositol 2-dehydrogenase activity
IB024_RS14455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IB024_RS14460	COG3962	Belongs to the TPP enzyme family
IB024_RS14470	COG3718	enzyme involved in inositol metabolism
IB024_RS14490	COG1840	ABC-type Fe3 transport system, periplasmic component
IB024_RS14500	COG1522	sequence-specific DNA binding
IB024_RS14515	COG0509	glycine decarboxylation via glycine cleavage system
IB024_RS14520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IB024_RS14570	COG4176	ABC-type proline glycine betaine transport system permease component
IB024_RS14595	COG1737	Transcriptional regulator
IB024_RS14620	COG0395	ABC-type sugar transport system, permease component
IB024_RS14635	COG1120	ATPase activity
IB024_RS14640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IB024_RS14665	COG1846	Transcriptional regulator
IB024_RS14685	COG0583	DNA-binding transcription factor activity
IB024_RS14695	COG0174	glutamine synthetase
IB024_RS14705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IB024_RS14750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IB024_RS14755	COG0363	glucosamine-6-phosphate deaminase activity
IB024_RS14760	COG0129	dihydroxy-acid dehydratase activity
IB024_RS14775	COG4172	Belongs to the ABC transporter superfamily
IB024_RS14780	COG0444	Belongs to the ABC transporter superfamily
IB024_RS14785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB024_RS14795	COG0747	negative chemotaxis
IB024_RS14805	COG0288	reversible hydration of carbon dioxide
IB024_RS14830	COG1024	Enoyl-CoA hydratase
IB024_RS14830	COG1250	3-hydroxyacyl-CoA dehydrogenase
IB024_RS14835	COG0183	Belongs to the thiolase family
IB024_RS14840	COG1960	acyl-CoA dehydrogenase activity
IB024_RS14850	COG0583	DNA-binding transcription factor activity
IB024_RS14870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB024_RS14875	COG0601	transmembrane transport
IB024_RS14880	COG0747	negative chemotaxis
IB024_RS14890	COG2721	sulfolactate sulfo-lyase activity
IB024_RS14895	COG4208	sulfate ABC transporter
IB024_RS14900	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB024_RS14905	COG3842	ATPase activity
IB024_RS14915	COG0246	Mannitol dehydrogenase
IB024_RS14925	COG1802	Transcriptional regulator
IB024_RS14950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB024_RS14970	COG1993	acr, cog1993
IB024_RS14975	COG0789	Transcriptional regulator
IB024_RS14985	COG0730	response to heat
IB024_RS15000	COG1201	RNA secondary structure unwinding
IB024_RS15150	COG0582	viral genome integration into host DNA
IB024_RS15175	COG1088	dTDP-glucose 4,6-dehydratase activity
IB024_RS15190	COG0546	phosphoglycolate phosphatase activity
IB024_RS15190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IB024_RS15195	COG1349	DNA-binding transcription factor activity
IB024_RS15205	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB024_RS15210	COG1129	ABC transporter
IB024_RS15245	COG1349	DNA-binding transcription factor activity
IB024_RS15275	COG1217	gtp-binding protein TYPA
IB024_RS15280	COG2239	Acts as a magnesium transporter
IB024_RS15285	COG0339	signal peptide processing
IB024_RS15315	COG1764	response to oxidative stress
IB024_RS15320	COG1846	Transcriptional regulator
IB024_RS15325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IB024_RS15335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IB024_RS15335	COG2169	Transcriptional regulator
IB024_RS15390	COG0010	Belongs to the arginase family
IB024_RS15400	COG1902	pentaerythritol trinitrate reductase activity
IB024_RS15405	COG0640	Transcriptional regulator
IB024_RS15410	COG2183	response to ionizing radiation
IB024_RS15415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IB024_RS15425	COG5383	Protein conserved in bacteria
IB024_RS15430	COG1012	belongs to the aldehyde dehydrogenase family
IB024_RS15450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IB024_RS15460	COG2188	Transcriptional regulator
IB024_RS15470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IB024_RS15485	COG0243	molybdopterin cofactor binding
IB024_RS15495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IB024_RS15500	COG1522	sequence-specific DNA binding
IB024_RS15520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IB024_RS15530	COG0402	S-adenosylhomocysteine deaminase activity
IB024_RS15565	COG4214	carbohydrate transport
IB024_RS15575	COG4213	ABC transporter substrate-binding protein
IB024_RS15580	COG0800	Aldolase
IB024_RS15585	COG3734	2-keto-3-deoxy-galactonokinase
IB024_RS15590	COG0129	dihydroxy-acid dehydratase activity
IB024_RS15605	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB024_RS15610	COG2186	Transcriptional regulator
IB024_RS15615	COG0028	Belongs to the TPP enzyme family
IB024_RS15625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IB024_RS15685	COG2011	ABC-type metal ion transport system permease component
IB024_RS15755	COG5001	Diguanylate cyclase
IB024_RS15760	COG1028	Short-chain dehydrogenase reductase Sdr
IB024_RS15765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IB024_RS15775	COG1609	Transcriptional regulator
IB024_RS15780	COG1846	Transcriptional regulator
IB024_RS15790	COG0523	cobalamin synthesis protein
IB024_RS15800	COG0400	carboxylic ester hydrolase activity
IB024_RS15805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IB024_RS15815	COG0251	oxidation-reduction process
IB024_RS15820	COG1172	Belongs to the binding-protein-dependent transport system permease family
IB024_RS15830	COG1129	ABC transporter
IB024_RS15835	COG1879	ABC-type sugar transport system periplasmic component
IB024_RS15875	COG3706	GGDEF domain
IB024_RS15880	COG0579	oxidoreductase
IB024_RS15885	COG2176	DNA-directed DNA polymerase activity
IB024_RS15890	COG0154	amidase activity
IB024_RS15895	COG4608	Belongs to the ABC transporter superfamily
IB024_RS15900	COG0444	Belongs to the ABC transporter superfamily
IB024_RS15905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IB024_RS15915	COG0747	negative chemotaxis
IB024_RS15930	COG1802	Transcriptional regulator
IB024_RS15935	COG2814	Major facilitator Superfamily
IB024_RS15950	COG0251	oxidation-reduction process
IB024_RS15980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IB024_RS16040	COG0242	peptide deformylase activity
IB024_RS16055	COG2827	Endonuclease containing a URI domain
IB024_RS16080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IB024_RS16105	COG1132	(ABC) transporter
IB024_RS16125	COG1228	amidohydrolase
IB024_RS16130	COG0778	Nitroreductase
IB024_RS16155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IB024_RS16165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IB024_RS16170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IB024_RS16175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IB024_RS16185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IB024_RS16260	COG2971	BadF BadG BcrA BcrD
IB024_RS16265	COG1959	2 iron, 2 sulfur cluster binding
IB024_RS16270	COG0523	cobalamin synthesis protein
IB024_RS16290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IB024_RS16295	COG0735	belongs to the Fur family
IB024_RS16330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IB024_RS16345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IB024_RS16395	COG1360	Flagellar Motor Protein
IB024_RS16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IB024_RS16425	COG4213	ABC transporter substrate-binding protein
IB024_RS16435	COG4214	carbohydrate transport
IB024_RS16455	COG0765	amino acid transport
IB024_RS16460	COG0765	amino acid transport
IB024_RS16470	COG1960	acyl-CoA dehydrogenase activity
IB024_RS16475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IB024_RS16480	COG1228	amidohydrolase
IB024_RS16490	COG2188	Transcriptional regulator
IB024_RS16495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IB024_RS16505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IB024_RS16515	COG3842	ATPase activity
IB024_RS16520	COG1177	transmembrane transport
IB024_RS16530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IB024_RS16550	COG1653	transport
IB024_RS16555	COG3833	ABC-type maltose transport systems, permease component
IB024_RS16560	COG1175	transmembrane transport
IB024_RS16565	COG3842	ATPase activity
IB024_RS16640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IB024_RS16670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IB024_RS16675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IB024_RS16695	COG3831	ATPase activity
IB024_RS16745	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB024_RS16750	COG4149	molybdate abc transporter
IB024_RS16755	COG3842	ATPase activity
IB024_RS16770	COG1902	pentaerythritol trinitrate reductase activity
IB024_RS16770	COG0446	pyridine nucleotide-disulphide oxidoreductase
IB024_RS16780	COG4423	Transcription factor
IB024_RS16785	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
IB024_RS16800	COG1175	transmembrane transport
IB024_RS16810	COG0395	ABC-type sugar transport system, permease component
IB024_RS16815	COG3842	ATPase activity
IB024_RS16825	COG1349	DNA-binding transcription factor activity
IB024_RS16830	COG1070	Carbohydrate kinase
IB024_RS16840	COG0434	BtpA family
IB024_RS16860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IB024_RS16905	COG1414	Transcriptional regulator
IB024_RS16910	COG1475	DNA binding
IB024_RS16915	COG1192	Involved in chromosome partitioning
IB024_RS16995	COG4608	Belongs to the ABC transporter superfamily
IB024_RS17005	COG1024	Enoyl-CoA hydratase
IB024_RS17035	COG1176	ABC-type spermidine putrescine transport system, permease component I
IB024_RS17045	COG1024	Enoyl-CoA hydratase
IB024_RS17050	COG1024	Enoyl-CoA hydratase
IB024_RS17055	COG1960	acyl-CoA dehydrogenase activity
IB024_RS17070	COG0028	Belongs to the TPP enzyme family
IB024_RS17075	COG1024	Enoyl-CoA hydratase
IB024_RS17075	COG1250	3-hydroxyacyl-CoA dehydrogenase
IB024_RS17080	COG2086	electron transfer activity
IB024_RS17085	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IB024_RS17090	COG0183	Belongs to the thiolase family