locus-tag	class	description
BSS2_RS00025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSS2_RS00030	COG4172	Belongs to the ABC transporter superfamily
BSS2_RS00035	COG4239	(ABC) transporter, permease
BSS2_RS00040	COG4174	ABC transporter (Permease)
BSS2_RS00050	COG4166	transmembrane transport
BSS2_RS00070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BSS2_RS00085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSS2_RS00090	COG1960	acyl-CoA dehydrogenase activity
BSS2_RS00095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSS2_RS00130	COG0539	negative regulation of cytoplasmic translation
BSS2_RS00140	COG0583	DNA-binding transcription factor activity
BSS2_RS00150	COG2951	lytic endotransglycosylase activity
BSS2_RS00165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSS2_RS00175	COG2816	NAD+ diphosphatase activity
BSS2_RS00180	COG1605	Chorismate mutase
BSS2_RS00180	COG0077	Prephenate dehydratase
BSS2_RS00190	COG3474	cytochrome
BSS2_RS00200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSS2_RS00205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSS2_RS00210	COG1845	cytochrome c oxidase, subunit III
BSS2_RS00215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSS2_RS00235	COG1376	ErfK ybiS ycfS ynhG family protein
BSS2_RS00260	COG0346	lactoylglutathione lyase activity
BSS2_RS00265	COG0489	protein tyrosine kinase activity
BSS2_RS00270	COG0033	Phosphoglucomutase
BSS2_RS00280	COG1073	alpha beta
BSS2_RS00285	COG1072	(Pantothenic acid kinase))
BSS2_RS00315	COG1272	protein, Hemolysin III
BSS2_RS00375	COG3339	Conserved Protein
BSS2_RS00390	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSS2_RS00400	COG4181	ATPase activity
BSS2_RS00410	COG0670	Belongs to the BI1 family
BSS2_RS00430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSS2_RS00440	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSS2_RS00445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSS2_RS00455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSS2_RS00500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSS2_RS00510	COG4208	sulfate ABC transporter
BSS2_RS00515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSS2_RS00520	COG3459	Glycosyltransferase 36 associated
BSS2_RS00530	COG0384	phenazine biosynthesis protein PhzF
BSS2_RS00535	COG2226	methyltransferase
BSS2_RS00545	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS00550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSS2_RS00565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSS2_RS00570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSS2_RS00575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSS2_RS00575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSS2_RS00590	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSS2_RS00600	COG2153	protein acetylation
BSS2_RS00615	COG1643	Atp-dependent helicase
BSS2_RS00620	COG1643	Atp-dependent helicase
BSS2_RS00630	COG3293	Transposase
BSS2_RS00640	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSS2_RS00650	COG1376	ErfK ybiS ycfS ynhG family protein
BSS2_RS00650	COG1388	LysM domain
BSS2_RS00655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSS2_RS00665	COG0180	Tryptophanyl-tRNA synthetase
BSS2_RS00670	COG0728	peptidoglycan biosynthetic process
BSS2_RS00680	COG0280	phosphate acetyltransferase
BSS2_RS00680	COG0281	malic enzyme
BSS2_RS00705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSS2_RS00710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSS2_RS00710	COG0116	Belongs to the methyltransferase superfamily
BSS2_RS00725	COG0616	signal peptide processing
BSS2_RS00735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BSS2_RS00740	COG1137	ATPase activity
BSS2_RS00745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSS2_RS00750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSS2_RS00755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSS2_RS00765	COG0071	Belongs to the small heat shock protein (HSP20) family
BSS2_RS00785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSS2_RS00790	COG2860	membrane
BSS2_RS00815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSS2_RS00820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSS2_RS00825	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSS2_RS00835	COG1648	precorrin-2 dehydrogenase activity
BSS2_RS00835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSS2_RS00845	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSS2_RS00850	COG0175	sulfate reduction
BSS2_RS00865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSS2_RS00885	COG2197	response regulator
BSS2_RS00890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSS2_RS00905	COG1218	3'(2'),5'-bisphosphate nucleotidase
BSS2_RS00920	COG2197	response regulator
BSS2_RS00940	COG1012	belongs to the aldehyde dehydrogenase family
BSS2_RS00970	COG1012	belongs to the aldehyde dehydrogenase family
BSS2_RS00975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSS2_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BSS2_RS00985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSS2_RS01010	COG0351	phosphomethylpyrimidine kinase
BSS2_RS01015	COG5001	Diguanylate cyclase
BSS2_RS01030	COG1174	glycine betaine transport
BSS2_RS01035	COG1125	glycine betaine transport
BSS2_RS01040	COG1174	glycine betaine transport
BSS2_RS01045	COG1732	Glycine betaine
BSS2_RS01055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSS2_RS01070	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSS2_RS01070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSS2_RS01085	COG1414	Transcriptional regulator
BSS2_RS01095	COG1175	transmembrane transport
BSS2_RS01100	COG0395	ABC-type sugar transport system, permease component
BSS2_RS01105	COG3842	ATPase activity
BSS2_RS01110	COG4948	Mandelate Racemase Muconate Lactonizing
BSS2_RS01115	COG3254	rhamnose metabolic process
BSS2_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS01140	COG4948	Mandelate Racemase Muconate Lactonizing
BSS2_RS01160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSS2_RS01175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSS2_RS01215	COG3617	BRO family, N-terminal domain
BSS2_RS01220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSS2_RS01285	COG4191	Histidine kinase
BSS2_RS01290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSS2_RS01295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSS2_RS01310	COG1309	transcriptional regulator
BSS2_RS01315	COG0494	nUDIX hydrolase
BSS2_RS01325	COG0493	'glutamate synthase
BSS2_RS01355	COG0318	PFAM AMP-dependent synthetase and ligase
BSS2_RS01390	COG2326	polyphosphate kinase activity
BSS2_RS01395	COG5002	protein histidine kinase activity
BSS2_RS01405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSS2_RS01415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSS2_RS01435	COG0717	Belongs to the dCTP deaminase family
BSS2_RS01455	COG0534	Mate efflux family protein
BSS2_RS01485	COG0784	Response regulator, receiver
BSS2_RS01485	COG2205	protein histidine kinase activity
BSS2_RS01495	COG0156	8-amino-7-oxononanoate synthase activity
BSS2_RS01520	COG0583	DNA-binding transcription factor activity
BSS2_RS01525	COG1380	Effector of murein hydrolase LrgA
BSS2_RS01530	COG1346	cytolysis
BSS2_RS01555	COG0019	diaminopimelate decarboxylase activity
BSS2_RS01595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSS2_RS01600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSS2_RS01605	COG3257	ureidoglycine aminohydrolase activity
BSS2_RS01610	COG3195	allantoin biosynthetic process
BSS2_RS01610	COG3648	Uricase
BSS2_RS01620	COG2080	2 iron, 2 sulfur cluster binding
BSS2_RS01625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSS2_RS01635	COG0583	DNA-binding transcription factor activity
BSS2_RS01645	COG0402	S-adenosylhomocysteine deaminase activity
BSS2_RS01700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSS2_RS01700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSS2_RS01710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSS2_RS01710	COG2169	Transcriptional regulator
BSS2_RS01715	COG1393	Belongs to the ArsC family
BSS2_RS01725	COG0477	Major facilitator Superfamily
BSS2_RS01735	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BSS2_RS01760	COG3773	Cell wall hydrolase
BSS2_RS01845	COG0142	geranyltranstransferase activity
BSS2_RS01860	COG0751	glycine-tRNA ligase activity
BSS2_RS01865	COG0751	glycine-tRNA ligase activity
BSS2_RS01870	COG0009	L-threonylcarbamoyladenylate synthase
BSS2_RS01900	COG1960	acyl-CoA dehydrogenase activity
BSS2_RS01915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSS2_RS01930	COG0484	heat shock protein binding
BSS2_RS01935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSS2_RS01945	COG1278	Cold shock
BSS2_RS01975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSS2_RS01975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSS2_RS01980	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSS2_RS01985	COG1722	exodeoxyribonuclease VII activity
BSS2_RS02005	COG1741	Belongs to the pirin family
BSS2_RS02015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BSS2_RS02040	COG5265	(ABC) transporter
BSS2_RS02050	COG1183	phosphatidylcholine synthase activity
BSS2_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS02060	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSS2_RS02075	COG0305	Participates in initiation and elongation during chromosome replication
BSS2_RS02080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSS2_RS02105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSS2_RS02120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSS2_RS02125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSS2_RS02130	COG1561	YicC-like family, N-terminal region
BSS2_RS02135	COG0194	GDP metabolic process
BSS2_RS02140	COG0312	modulator of DNA gyrase
BSS2_RS02150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSS2_RS02155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSS2_RS02205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSS2_RS02205	COG0678	peroxiredoxin activity
BSS2_RS02225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSS2_RS02230	COG0612	Peptidase, M16
BSS2_RS02245	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BSS2_RS02255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSS2_RS02275	COG1194	a g-specific adenine glycosylase
BSS2_RS02290	COG1196	nuclear chromosome segregation
BSS2_RS02305	COG0574	Belongs to the PEP-utilizing enzyme family
BSS2_RS02305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSS2_RS02330	COG1268	BioY protein
BSS2_RS02355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSS2_RS02385	COG2801	Transposase and inactivated derivatives
BSS2_RS02415	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BSS2_RS02420	COG3293	Transposase
BSS2_RS02430	COG3293	Transposase
BSS2_RS02450	COG3293	Transposase
BSS2_RS02460	COG2801	Transposase and inactivated derivatives
BSS2_RS02465	COG3293	Transposase
BSS2_RS02480	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BSS2_RS02480	COG0662	Cupin 2, conserved barrel domain protein
BSS2_RS02485	COG2942	2-epimerase
BSS2_RS02490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSS2_RS02490	COG0438	transferase activity, transferring glycosyl groups
BSS2_RS02495	COG1129	ABC transporter
BSS2_RS02500	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSS2_RS02505	COG1879	ABC-type sugar transport system periplasmic component
BSS2_RS02515	COG0673	inositol 2-dehydrogenase activity
BSS2_RS02525	COG1070	Carbohydrate kinase
BSS2_RS02560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSS2_RS02570	COG2336	PFAM SpoVT AbrB
BSS2_RS02580	COG2186	Transcriptional regulator
BSS2_RS02585	COG2807	transmembrane transport
BSS2_RS02595	COG0433	COG0433 Predicted ATPase
BSS2_RS02600	COG1376	ErfK ybiS ycfS ynhG family protein
BSS2_RS02610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSS2_RS02625	COG4957	zinc ion binding
BSS2_RS02635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSS2_RS02650	COG2166	iron-sulfur cluster assembly
BSS2_RS02660	COG2205	protein histidine kinase activity
BSS2_RS02690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSS2_RS02705	COG4695	Portal protein
BSS2_RS02805	COG4235	cytochrome complex assembly
BSS2_RS02815	COG1138	Cytochrome C-type biogenesis protein
BSS2_RS02820	COG3088	subunit of a heme lyase
BSS2_RS02850	COG2205	protein histidine kinase activity
BSS2_RS02850	COG2202	Pas domain
BSS2_RS02855	COG0308	aminopeptidase N
BSS2_RS02870	COG1573	uracil-dna glycosylase
BSS2_RS02885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSS2_RS02900	COG0625	glutathione transferase activity
BSS2_RS02935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSS2_RS02940	COG4974	Belongs to the 'phage' integrase family
BSS2_RS02970	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSS2_RS02970	COG3743	rRNA binding
BSS2_RS02975	COG0741	lytic transglycosylase activity
BSS2_RS03015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSS2_RS03020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSS2_RS03025	COG2223	nitrite transmembrane transporter activity
BSS2_RS03030	COG2207	Transcriptional regulator
BSS2_RS03045	COG0681	Belongs to the peptidase S26 family
BSS2_RS03070	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BSS2_RS03080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSS2_RS03100	COG0494	nUDIX hydrolase
BSS2_RS03125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSS2_RS03135	COG0739	heme binding
BSS2_RS03145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSS2_RS03150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSS2_RS03155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSS2_RS03185	COG0488	(ABC) transporter
BSS2_RS03205	COG0314	molybdopterin synthase activity
BSS2_RS03210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BSS2_RS03215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSS2_RS03250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSS2_RS03260	COG0243	molybdopterin cofactor binding
BSS2_RS03270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSS2_RS03280	COG0628	permease
BSS2_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS03310	COG1620	l-lactate permease
BSS2_RS03415	COG0626	cystathionine gamma-synthase activity
BSS2_RS03425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSS2_RS03430	COG4597	amino acid ABC transporter
BSS2_RS03435	COG0765	amino acid transport
BSS2_RS03440	COG1126	abc transporter atp-binding protein
BSS2_RS03455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSS2_RS03465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSS2_RS03480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSS2_RS03495	COG0113	porphobilinogen synthase activity
BSS2_RS03515	COG2989	Protein conserved in bacteria
BSS2_RS03530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSS2_RS03530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSS2_RS03555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSS2_RS03635	COG0010	Belongs to the arginase family
BSS2_RS03705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSS2_RS03725	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BSS2_RS03730	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSS2_RS03770	COG1007	ATP synthesis coupled electron transport
BSS2_RS03785	COG0346	lactoylglutathione lyase activity
BSS2_RS03840	COG0483	inositol monophosphate 1-phosphatase activity
BSS2_RS03845	COG2814	Major facilitator Superfamily
BSS2_RS03880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSS2_RS03905	COG2514	catechol 2,3-dioxygenase activity
BSS2_RS03910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSS2_RS03930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSS2_RS03935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSS2_RS03940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSS2_RS03955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSS2_RS03960	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BSS2_RS03965	COG3454	Phosphonate metabolism
BSS2_RS03970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSS2_RS03980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSS2_RS04005	COG1522	sequence-specific DNA binding
BSS2_RS04010	COG1573	uracil-dna glycosylase
BSS2_RS04035	COG0316	Belongs to the HesB IscA family
BSS2_RS04055	COG1472	Belongs to the glycosyl hydrolase 3 family
BSS2_RS04060	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSS2_RS04065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSS2_RS04075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSS2_RS04080	COG0805	protein transport
BSS2_RS04095	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSS2_RS04115	COG1862	Preprotein translocase
BSS2_RS04180	COG4765	Protein conserved in bacteria
BSS2_RS04190	COG0439	Biotin carboxylase
BSS2_RS04195	COG0511	ligase activity, forming carbon-carbon bonds
BSS2_RS04210	COG0501	Belongs to the peptidase M48B family
BSS2_RS04215	COG0436	Aminotransferase
BSS2_RS04220	COG1530	ribonuclease E activity
BSS2_RS04230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSS2_RS04235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSS2_RS04245	COG3293	Transposase
BSS2_RS04255	COG2833	Protein of unknown function (DUF455)
BSS2_RS04260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSS2_RS04285	COG2945	thiolester hydrolase activity
BSS2_RS04295	COG0719	Fe-S assembly protein
BSS2_RS04300	COG0396	ATPase activity
BSS2_RS04305	COG0719	Fe-S assembly protein
BSS2_RS04310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSS2_RS04315	COG2151	metal-sulfur cluster biosynthetic enzyme
BSS2_RS04335	COG0513	Belongs to the DEAD box helicase family
BSS2_RS04340	COG0316	Belongs to the HesB IscA family
BSS2_RS04355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSS2_RS04385	COG2084	Dehydrogenase
BSS2_RS04390	COG0625	glutathione transferase activity
BSS2_RS04445	COG2989	Protein conserved in bacteria
BSS2_RS04540	COG3293	Transposase
BSS2_RS04580	COG1393	Belongs to the ArsC family
BSS2_RS04610	COG0084	hydrolase, TatD family'
BSS2_RS04645	COG0174	glutamine synthetase
BSS2_RS04650	COG0347	Belongs to the P(II) protein family
BSS2_RS04655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSS2_RS04655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSS2_RS04665	COG0546	phosphoglycolate phosphatase activity
BSS2_RS04685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSS2_RS04690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BSS2_RS04710	COG0281	malic enzyme
BSS2_RS04710	COG0280	phosphate acetyltransferase
BSS2_RS04715	COG4948	Mandelate Racemase Muconate Lactonizing
BSS2_RS04720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSS2_RS04725	COG1127	ABC transporter
BSS2_RS04745	COG0633	Ferredoxin
BSS2_RS04760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSS2_RS04770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSS2_RS04785	COG3106	COG3106 Predicted ATPase
BSS2_RS04810	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BSS2_RS04825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSS2_RS04845	COG1546	Belongs to the CinA family
BSS2_RS04845	COG1058	Belongs to the CinA family
BSS2_RS04860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSS2_RS04865	COG0513	Belongs to the DEAD box helicase family
BSS2_RS04870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSS2_RS04875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSS2_RS04880	COG2897	thiosulfate sulfurtransferase activity
BSS2_RS04895	COG0427	acetyl-CoA hydrolase
BSS2_RS04900	COG2814	Major facilitator Superfamily
BSS2_RS04905	COG1566	PFAM secretion protein HlyD family protein
BSS2_RS04915	COG0006	proline dipeptidase activity
BSS2_RS04920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSS2_RS04930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSS2_RS04935	COG3956	TIGRFAM MazG family protein
BSS2_RS04940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSS2_RS04960	COG1686	Belongs to the peptidase S11 family
BSS2_RS04985	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSS2_RS05015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSS2_RS05020	COG3617	BRO family, N-terminal domain
BSS2_RS05030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSS2_RS05035	COG1960	acyl-CoA dehydrogenase activity
BSS2_RS05040	COG0583	DNA-binding transcription factor activity
BSS2_RS05045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSS2_RS05050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSS2_RS05055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSS2_RS05095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSS2_RS05100	COG2095	MarC family integral membrane protein
BSS2_RS05110	COG2188	Transcriptional regulator
BSS2_RS05145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSS2_RS05160	COG0569	domain protein
BSS2_RS05165	COG2204	response regulator
BSS2_RS05170	COG5000	phosphorelay sensor kinase activity
BSS2_RS05175	COG2204	response regulator
BSS2_RS05180	COG3852	Histidine kinase
BSS2_RS05195	COG1058	Belongs to the CinA family
BSS2_RS05195	COG1546	Belongs to the CinA family
BSS2_RS05200	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS05205	COG2867	negative regulation of translational initiation
BSS2_RS05220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSS2_RS05225	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSS2_RS05230	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSS2_RS05230	COG0022	dehydrogenase e1 component
BSS2_RS05235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSS2_RS05240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BSS2_RS05280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSS2_RS05300	COG0303	'Molybdopterin
BSS2_RS05310	COG0658	competence protein
BSS2_RS05310	COG2333	competence protein COMEC
BSS2_RS05320	COG0372	Belongs to the citrate synthase family
BSS2_RS05325	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSS2_RS05350	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSS2_RS05405	COG0584	glycerophosphoryl diester phosphodiesterase
BSS2_RS05415	COG0537	adenosine 5'-monophosphoramidase activity
BSS2_RS05430	COG1686	Belongs to the peptidase S11 family
BSS2_RS05445	COG1760	l-serine dehydratase
BSS2_RS05495	COG3800	Transcriptional regulator
BSS2_RS05495	COG1396	sequence-specific DNA binding
BSS2_RS05505	COG4770	biotin carboxylase activity
BSS2_RS05510	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSS2_RS05510	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSS2_RS05525	COG2358	TRAP transporter, solute receptor (TAXI family
BSS2_RS05535	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BSS2_RS05540	COG0693	protein deglycase activity
BSS2_RS05550	COG0538	isocitrate dehydrogenase activity
BSS2_RS05555	COG1785	Belongs to the alkaline phosphatase family
BSS2_RS05570	COG2885	chlorophyll binding
BSS2_RS05580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSS2_RS05585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSS2_RS05630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSS2_RS05695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSS2_RS05785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSS2_RS05810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSS2_RS05865	COG0346	lactoylglutathione lyase activity
BSS2_RS05885	COG1494	fructose-1,6-bisphosphatase
BSS2_RS05895	COG0436	Aminotransferase
BSS2_RS05930	COG0024	Methionine aminopeptidase
BSS2_RS05980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSS2_RS06140	COG4651	solute:proton antiporter activity
BSS2_RS06140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSS2_RS06155	COG4208	sulfate ABC transporter
BSS2_RS06160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BSS2_RS06165	COG4150	thiosulfate binding
BSS2_RS06175	COG1253	flavin adenine dinucleotide binding
BSS2_RS06180	COG0586	Pfam SNARE associated Golgi protein
BSS2_RS06195	COG4154	Belongs to the RbsD FucU family
BSS2_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS06210	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSS2_RS06225	COG1120	ATPase activity
BSS2_RS06230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSS2_RS06245	COG0842	Transport permease protein
BSS2_RS06250	COG0842	Transport permease protein
BSS2_RS06250	COG1129	ABC transporter
BSS2_RS06255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSS2_RS06260	COG1649	PFAM Uncharacterised BCR, COG1649
BSS2_RS06300	COG4413	Urea transporter
BSS2_RS06310	COG0310	cobalt ion transport
BSS2_RS06350	COG0384	phenazine biosynthesis protein PhzF
BSS2_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSS2_RS06405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSS2_RS06410	COG0440	acetolactate synthase activity
BSS2_RS06415	COG0028	Belongs to the TPP enzyme family
BSS2_RS06425	COG0560	Phosphoserine phosphatase
BSS2_RS06430	COG2081	HI0933 family
BSS2_RS06445	COG0330	HflC and HflK could
BSS2_RS06470	COG2814	Major facilitator Superfamily
BSS2_RS06510	COG0277	FAD linked oxidase domain protein
BSS2_RS06525	COG0210	DNA helicase
BSS2_RS06540	COG1999	signal sequence binding
BSS2_RS06550	COG0006	proline dipeptidase activity
BSS2_RS06570	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSS2_RS06580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSS2_RS06585	COG0849	cell division
BSS2_RS06590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSS2_RS06655	COG1914	H( )-stimulated, divalent metal cation uptake system
BSS2_RS06670	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSS2_RS06675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BSS2_RS06705	COG0640	Transcriptional regulator
BSS2_RS06715	COG0477	Major facilitator Superfamily
BSS2_RS06730	COG2267	carboxylic ester hydrolase activity
BSS2_RS06755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSS2_RS06760	COG2824	Alkylphosphonate utilization operon protein PhnA
BSS2_RS06765	COG1335	isochorismatase
BSS2_RS06780	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BSS2_RS06820	COG2968	Membrane
BSS2_RS06840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSS2_RS06845	COG0358	DNA primase activity
BSS2_RS06865	COG2321	neutral zinc metallopeptidase
BSS2_RS06885	COG1136	(ABC) transporter
BSS2_RS06895	COG1278	Cold shock
BSS2_RS06900	COG0625	glutathione transferase activity
BSS2_RS06905	COG0436	Aminotransferase
BSS2_RS06910	COG0583	DNA-binding transcription factor activity
BSS2_RS06915	COG0492	ferredoxin-NADP+ reductase activity
BSS2_RS06920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSS2_RS06925	COG1522	sequence-specific DNA binding
BSS2_RS06970	COG0556	nucleotide-excision repair
BSS2_RS06975	COG1196	nuclear chromosome segregation
BSS2_RS06975	COG0741	lytic transglycosylase activity
BSS2_RS06975	COG0739	heme binding
BSS2_RS06980	COG1278	Cold shock
BSS2_RS06995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSS2_RS07010	COG1846	Transcriptional regulator
BSS2_RS07015	COG0745	RESPONSE REGULATOR receiver
BSS2_RS07020	COG2205	protein histidine kinase activity
BSS2_RS07030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSS2_RS07055	COG1496	oxidoreductase activity
BSS2_RS07090	COG0012	GTP binding
BSS2_RS07095	COG2030	dehydratase
BSS2_RS07110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSS2_RS07110	COG2857	Cytochrome c1
BSS2_RS07125	COG1132	(ABC) transporter
BSS2_RS07135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSS2_RS07155	COG3153	acetyltransferase
BSS2_RS07170	COG0617	tRNA 3'-terminal CCA addition
BSS2_RS07185	COG0714	Associated with various cellular activities
BSS2_RS07210	COG0435	Glutathione S-transferase
BSS2_RS07215	COG3047	cAMP biosynthetic process
BSS2_RS07220	COG1051	belongs to the nudix hydrolase family
BSS2_RS07235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSS2_RS07240	COG0512	Glutamine amidotransferase of anthranilate synthase
BSS2_RS07240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSS2_RS07250	COG1522	sequence-specific DNA binding
BSS2_RS07280	COG4176	ABC-type proline glycine betaine transport system permease component
BSS2_RS07285	COG4175	Glycine betaine
BSS2_RS07290	COG4608	Belongs to the ABC transporter superfamily
BSS2_RS07295	COG0444	Belongs to the ABC transporter superfamily
BSS2_RS07300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSS2_RS07305	COG0601	transmembrane transport
BSS2_RS07310	COG0747	negative chemotaxis
BSS2_RS07315	COG0747	negative chemotaxis
BSS2_RS07320	COG0747	negative chemotaxis
BSS2_RS07415	COG1177	transmembrane transport
BSS2_RS07420	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSS2_RS07425	COG3842	ATPase activity
BSS2_RS07440	COG2224	Isocitrate lyase
BSS2_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS07460	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS07475	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BSS2_RS07490	COG1461	Dihydroxyacetone kinase
BSS2_RS07495	COG2376	Dihydroxyacetone kinase
BSS2_RS07500	COG1461	Dihydroxyacetone kinase
BSS2_RS07505	COG2376	Dihydroxyacetone kinase
BSS2_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS07515	COG1879	ABC-type sugar transport system periplasmic component
BSS2_RS07520	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSS2_RS07525	COG1129	ABC transporter
BSS2_RS07535	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSS2_RS07580	COG1012	belongs to the aldehyde dehydrogenase family
BSS2_RS07605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSS2_RS07620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSS2_RS07625	COG0564	pseudouridine synthase activity
BSS2_RS07645	COG3920	Histidine kinase
BSS2_RS07645	COG2202	Pas domain
BSS2_RS07655	COG0784	Response regulator, receiver
BSS2_RS07670	COG3920	Histidine kinase
BSS2_RS07705	COG0848	biopolymer transport protein
BSS2_RS07725	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSS2_RS07725	COG1136	(ABC) transporter
BSS2_RS07730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSS2_RS07735	COG3293	Transposase
BSS2_RS07750	COG1522	sequence-specific DNA binding
BSS2_RS07770	COG0477	Major facilitator Superfamily
BSS2_RS07790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSS2_RS07800	COG0385	Bile acid
BSS2_RS07815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSS2_RS07835	COG2885	chlorophyll binding
BSS2_RS07850	COG0848	biopolymer transport protein
BSS2_RS07905	COG0483	inositol monophosphate 1-phosphatase activity
BSS2_RS07920	COG1132	(ABC) transporter
BSS2_RS07950	COG1253	flavin adenine dinucleotide binding
BSS2_RS07955	COG1692	metallophosphoesterase
BSS2_RS08020	COG0604	alcohol dehydrogenase
BSS2_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS08020	COG3321	synthase
BSS2_RS08050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSS2_RS08060	COG0457	Tetratricopeptide repeat
BSS2_RS08065	COG0469	pyruvate kinase activity
BSS2_RS08085	COG0488	(ABC) transporter
BSS2_RS08120	COG2258	MOSC domain
BSS2_RS08125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSS2_RS08130	COG1329	Transcriptional regulator
BSS2_RS08135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSS2_RS08150	COG0183	Belongs to the thiolase family
BSS2_RS08170	COG0142	geranyltranstransferase activity
BSS2_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS08185	COG0738	Major facilitator superfamily
BSS2_RS08190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSS2_RS08225	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSS2_RS08300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSS2_RS08310	COG5425	PFAM Usg family protein
BSS2_RS08330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSS2_RS08330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSS2_RS08345	COG2270	Major facilitator Superfamily
BSS2_RS08360	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BSS2_RS08365	COG1704	LemA family
BSS2_RS08375	COG1605	Chorismate mutase
BSS2_RS08375	COG0287	Prephenate dehydrogenase
BSS2_RS08380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSS2_RS08390	COG0288	reversible hydration of carbon dioxide
BSS2_RS08430	COG0793	Belongs to the peptidase S41A family
BSS2_RS08450	COG0799	negative regulation of ribosome biogenesis
BSS2_RS08515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BSS2_RS08565	COG0739	heme binding
BSS2_RS08570	COG1376	ErfK ybiS ycfS ynhG family protein
BSS2_RS08585	COG2890	protein-(glutamine-N5) methyltransferase activity
BSS2_RS08600	COG0527	aspartate kinase activity
BSS2_RS08630	COG1040	competence protein
BSS2_RS08635	COG2226	methyltransferase
BSS2_RS08690	COG2264	protein methyltransferase activity
BSS2_RS08695	COG0697	spore germination
BSS2_RS08710	COG0004	ammonium transporteR
BSS2_RS08715	COG1946	Acyl-CoA thioesterase
BSS2_RS08720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSS2_RS08765	COG1953	Uracil, thiamine, allantoin
BSS2_RS08825	COG1280	lysine exporter protein (LysE YggA)
BSS2_RS08835	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSS2_RS08845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSS2_RS08860	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSS2_RS08875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSS2_RS08880	COG0552	protein localization to endoplasmic reticulum
BSS2_RS08905	COG0494	nUDIX hydrolase
BSS2_RS08920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSS2_RS08940	COG2194	sulfuric ester hydrolase activity
BSS2_RS08960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSS2_RS08965	COG0765	amino acid transport
BSS2_RS08970	COG0765	amino acid transport
BSS2_RS08990	COG1126	abc transporter atp-binding protein
BSS2_RS09000	COG1802	Transcriptional regulator
BSS2_RS09005	COG0252	asparaginase activity
BSS2_RS09035	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSS2_RS09040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BSS2_RS09045	COG2086	electron transfer activity
BSS2_RS09055	COG0720	synthase
BSS2_RS09060	COG0602	queuosine metabolic process
BSS2_RS09075	COG0300	oxidoreductase activity
BSS2_RS09090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSS2_RS09120	COG2226	methyltransferase
BSS2_RS09130	COG0287	Prephenate dehydrogenase
BSS2_RS09155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSS2_RS09175	COG2884	Cell division ATP-binding protein ftsE
BSS2_RS09190	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSS2_RS09245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BSS2_RS09260	COG0789	Transcriptional regulator
BSS2_RS09265	COG2217	Heavy metal translocating P-type atpase
BSS2_RS09300	COG4536	flavin adenine dinucleotide binding
BSS2_RS09340	COG0523	cobalamin synthesis protein
BSS2_RS09345	COG1686	Belongs to the peptidase S11 family
BSS2_RS09350	COG1473	amidohydrolase
BSS2_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
BSS2_RS09390	COG1012	belongs to the aldehyde dehydrogenase family
BSS2_RS09395	COG1024	Enoyl-CoA hydratase
BSS2_RS09420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSS2_RS09430	COG4120	Belongs to the binding-protein-dependent transport system permease family
BSS2_RS09435	COG1122	ATPase activity
BSS2_RS09470	COG1331	Highly conserved protein containing a thioredoxin domain
BSS2_RS09475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSS2_RS09485	COG1981	membrane
BSS2_RS09510	COG0237	dephospho-CoA kinase activity
BSS2_RS09530	COG4395	Tim44
BSS2_RS09540	COG2840	Smr protein MutS2
BSS2_RS09545	COG1396	sequence-specific DNA binding
BSS2_RS09610	COG0745	RESPONSE REGULATOR receiver
BSS2_RS09615	COG2205	protein histidine kinase activity
BSS2_RS09625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSS2_RS09625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSS2_RS09630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSS2_RS09640	COG2205	protein histidine kinase activity
BSS2_RS09645	COG3178	'Phosphotransferase
BSS2_RS09650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSS2_RS09655	COG2887	Belongs to the helicase family. UvrD subfamily
BSS2_RS09660	COG1074	ATP-dependent DNA helicase activity
BSS2_RS09670	COG0285	dihydrofolate synthase activity
BSS2_RS09700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BSS2_RS09715	COG3135	benzoate transporter
BSS2_RS09730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSS2_RS09780	COG3963	phosphatidate phosphatase activity
BSS2_RS09795	COG3386	PFAM SMP-30 Gluconolaconase
BSS2_RS09805	COG0606	chelatase, subunit chli
BSS2_RS09815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSS2_RS09820	COG2832	Protein of unknown function (DUF454)
BSS2_RS09825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSS2_RS09830	COG0573	inorganic phosphate transmembrane transporter activity
BSS2_RS09840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSS2_RS09845	COG0704	Plays a role in the regulation of phosphate uptake
BSS2_RS09850	COG0745	RESPONSE REGULATOR receiver
BSS2_RS09855	COG3773	Cell wall hydrolase
BSS2_RS09865	COG2309	aminopeptidase activity
BSS2_RS09870	COG0783	Belongs to the Dps family
BSS2_RS09880	COG0456	acetyltransferase
BSS2_RS09915	COG1396	sequence-specific DNA binding
BSS2_RS09920	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSS2_RS09935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSS2_RS09935	COG0195	Participates in both transcription termination and antitermination
BSS2_RS09970	COG2813	Specifically methylates the guanine in position
BSS2_RS09975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSS2_RS10015	COG0791	NLP P60 protein
BSS2_RS10025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSS2_RS10040	COG1024	Enoyl-CoA hydratase
BSS2_RS10220	COG0539	negative regulation of cytoplasmic translation
BSS2_RS10655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSS2_RS11000	COG0646	methionine synthase
BSS2_RS11000	COG1410	methionine synthase
BSS2_RS11015	COG1410	methionine synthase
BSS2_RS11015	COG0646	methionine synthase
BSS2_RS11230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSS2_RS11230	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSS2_RS11265	COG0395	ABC-type sugar transport system, permease component
BSS2_RS11595	COG0534	Mate efflux family protein
BSS2_RS12890	COG3088	subunit of a heme lyase
BSS2_RS13155	COG0681	Belongs to the peptidase S26 family
BSS2_RS13250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSS2_RS13850	COG0587	DNA-directed DNA polymerase activity
BSS2_RS14200	COG0439	Biotin carboxylase
BSS2_RS14225	COG0501	Belongs to the peptidase M48B family
BSS2_RS14690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSS2_RS15070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSS2_RS15075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSS2_RS15190	COG2204	response regulator