locus-tag	class	description
GUU85_RS00010	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GUU85_RS00020	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GUU85_RS00050	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GUU85_RS00055	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GUU85_RS00060	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GUU85_RS00065	ENOG4105VG0	50S ribosomal protein l34
GUU85_RS00070	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GUU85_RS00100	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GUU85_RS00105	ENOG4106CVF	DNA replication protein
GUU85_RS00115	ENOG4106H78	methyltransferase
GUU85_RS00120	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GUU85_RS00125	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GUU85_RS00130	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GUU85_RS00140	ENOG4105DQF	Hydrolase
GUU85_RS00145	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GUU85_RS00155	ENOG4105K70	DNA-binding protein
GUU85_RS00160	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GUU85_RS00190	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GUU85_RS00195	ENOG4105PM1	preprotein translocase subunit SecE
GUU85_RS00220	ENOG4105D4A	Cell wall formation (By similarity)
GUU85_RS00225	ENOG4105SYT	Methylenetetrahydrofolate reductase
GUU85_RS00235	ENOG4105CH7	arginosuccinase
GUU85_RS00240	ENOG4107YZP	Rhodanese domain protein
GUU85_RS00250	ENOG4105D7W	serine acetyltransferase
GUU85_RS00255	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GUU85_RS00260	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GUU85_RS00265	ENOG4105VCC	30S ribosomal protein S21
GUU85_RS00280	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GUU85_RS00295	ENOG4105C5Y	PTS System
GUU85_RS00300	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GUU85_RS00305	ENOG4105KZ7	phosphocarrier protein hpr
GUU85_RS00310	ENOG4105C6T	cysteine synthase
GUU85_RS00330	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GUU85_RS00340	ENOG41081BH	flagellar hook-basal body complex protein fliE
GUU85_RS00345	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GUU85_RS00350	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GUU85_RS00355	ENOG4108CG0	Flagellar assembly protein
GUU85_RS00360	ENOG4108JIR	Flagellum-specific ATP synthase
GUU85_RS00380	ENOG4105DD5	Flagellar motor switch protein
GUU85_RS00385	ENOG4105CN7	Flagellar biosynthetic protein FliP
GUU85_RS00390	ENOG4105VS8	Flagellar biosynthetic protein fliq
GUU85_RS00395	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GUU85_RS00400	ENOG4105W0E	50S ribosomal protein L33
GUU85_RS00405	ENOG4105KDC	50s ribosomal protein l28
GUU85_RS00415	ENOG4105F0N	pyrophosphate phospho-hydrolase
GUU85_RS00420	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GUU85_RS00430	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GUU85_RS00435	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GUU85_RS00445	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GUU85_RS00450	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GUU85_RS00480	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GUU85_RS00485	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GUU85_RS00495	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GUU85_RS00505	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GUU85_RS00510	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GUU85_RS00515	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GUU85_RS00520	ENOG4105DHP	deoxycytidine triphosphate deaminase
GUU85_RS00540	ENOG4108R6K	riboflavin synthase, subunit alpha
GUU85_RS00545	ENOG4105CSM	endonuclease III
GUU85_RS00550	ENOG4105C25	Primosomal protein n'
GUU85_RS00560	ENOG4108Z4V	iron-sulfur cluster assembly
GUU85_RS00565	ENOG4105IPI	Membrane
GUU85_RS00570	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GUU85_RS00575	ENOG4105C22	threonyL-tRNA synthetase
GUU85_RS00580	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GUU85_RS00585	ENOG41082NX	50s ribosomal protein l35
GUU85_RS00595	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GUU85_RS00600	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GUU85_RS00615	ENOG4105VIE	preprotein translocase, subunit YajC
GUU85_RS00640	ENOG4108KF1	Membrane
GUU85_RS00645	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GUU85_RS00650	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GUU85_RS00655	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GUU85_RS00660	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GUU85_RS00665	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GUU85_RS00670	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GUU85_RS00690	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GUU85_RS00695	ENOG4105DTN	riboflavin biosynthesis protein ribF
GUU85_RS00715	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GUU85_RS00725	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUU85_RS00730	ENOG4105GKE	subunit e
GUU85_RS00735	ENOG4107QIZ	NADH dehydrogenase
GUU85_RS00740	ENOG4107R0R	NADH dehydrogenase subunit g
GUU85_RS00750	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUU85_RS00755	ENOG4107UFS	subunit j
GUU85_RS00765	ENOG4105D65	subunit l
GUU85_RS00770	ENOG4105C8S	subunit m
GUU85_RS00775	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GUU85_RS00780	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GUU85_RS00790	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GUU85_RS00795	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GUU85_RS00805	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GUU85_RS00810	ENOG41063JG	Transcriptional regulator
GUU85_RS00820	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GUU85_RS00825	ENOG4105C6K	Malic enzyme
GUU85_RS00830	ENOG4105XPH	Ferredoxin
GUU85_RS00835	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GUU85_RS00840	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GUU85_RS00845	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GUU85_RS00850	ENOG4105G4C	Periplasmic ligand-binding sensor protein
GUU85_RS00855	ENOG4105D3R	alkyl hydroperoxide reductase
GUU85_RS00865	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GUU85_RS00880	ENOG4105M2J	Glutaredoxin
GUU85_RS00885	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GUU85_RS00890	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GUU85_RS00900	ENOG4105C3G	gtp-binding protein
GUU85_RS00905	ENOG4105D98	threonine synthase
GUU85_RS00915	ENOG4105CFH	Aspartokinase
GUU85_RS00920	ENOG4107XRV	hypoxanthine phosphoribosyltransferase
GUU85_RS00925	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GUU85_RS00935	ENOG4105BZ4	penicillin-binding protein
GUU85_RS00945	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GUU85_RS00955	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GUU85_RS00960	ENOG4107QSN	dihydrolipoamide acetyltransferase
GUU85_RS00965	ENOG4107QN2	dihydrolipoyl dehydrogenase
GUU85_RS00975	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GUU85_RS00980	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GUU85_RS00985	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GUU85_RS00990	ENOG4105CPF	Cell wall formation (By similarity)
GUU85_RS01005	ENOG4105CNI	cell division protein FtsW
GUU85_RS01025	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GUU85_RS01030	ENOG4105CJN	penicillin-binding protein
GUU85_RS01045	ENOG4108ZP8	Acetolactate synthase small subunit
GUU85_RS01050	ENOG4105C7K	acetolactate synthase
GUU85_RS01055	ENOG4105C0H	protease
GUU85_RS01060	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GUU85_RS01065	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GUU85_RS01080	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GUU85_RS01090	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GUU85_RS01095	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GUU85_RS01100	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GUU85_RS01120	ENOG4105D00	flagellar biosynthetic protein flhB
GUU85_RS01125	ENOG4105D7B	Flagellar biosynthesis protein flha
GUU85_RS01150	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GUU85_RS01155	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GUU85_RS01160	ENOG4107RZZ	dna polymerase iii epsilon subunit
GUU85_RS01175	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GUU85_RS01180	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GUU85_RS01190	ENOG4108Z6B	deaminase
GUU85_RS01210	ENOG4105C3F	Signal peptidase i
GUU85_RS01220	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GUU85_RS01225	ENOG4107QTF	adenylosuccinate lyase
GUU85_RS01230	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GUU85_RS01235	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GUU85_RS01245	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GUU85_RS01250	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GUU85_RS01265	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GUU85_RS01275	ENOG4105NAU	thioesterase Superfamily protein
GUU85_RS01280	ENOG4107835	probably involved in intracellular septation (By similarity)
GUU85_RS01295	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GUU85_RS01300	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GUU85_RS01310	ENOG4105DWP	Membrane
GUU85_RS01315	ENOG4105FE9	pseudouridine synthase
GUU85_RS01320	ENOG4105ERU	peptidase
GUU85_RS01325	ENOG4105ECY	inositol monophosphatase
GUU85_RS01330	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GUU85_RS01335	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GUU85_RS01340	ENOG4105CUT	histidyl-tRNA synthetase
GUU85_RS01355	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GUU85_RS01360	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GUU85_RS01365	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GUU85_RS01370	ENOG4108JA2	transcriptioN-repair coupling factor
GUU85_RS01375	ENOG4105D60	lipoprotein releasing system transmembrane protein
GUU85_RS01380	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GUU85_RS01390	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GUU85_RS01395	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GUU85_RS01400	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GUU85_RS01405	ENOG4107QNR	UPF0135 protein
GUU85_RS01410	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GUU85_RS01415	ENOG4105C7S	Dehydrogenase
GUU85_RS01430	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GUU85_RS01435	ENOG4105CP7	Triose-phosphate isomerase
GUU85_RS01445	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GUU85_RS01465	ENOG4105C3M	thioredoxin reductase
GUU85_RS01470	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GUU85_RS01475	ENOG4105C9M	aspartyl-trna synthetase
GUU85_RS01480	ENOG4105FAV	ABC, transporter
GUU85_RS01485	ENOG4105FDK	ABC transporter
GUU85_RS01490	ENOG4105CA9	Pyruvate kinase
GUU85_RS01495	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GUU85_RS01505	ENOG4105VEQ	Cold shock protein
GUU85_RS01510	ENOG4105EE5	Membrane protein terC
GUU85_RS01525	ENOG4107QMS	site-determining protein
GUU85_RS01535	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GUU85_RS01540	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GUU85_RS01560	ENOG4105UYK	outer membrane protein a
GUU85_RS01565	ENOG4105CJR	Integral membrane protein (MviN
GUU85_RS01575	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
GUU85_RS01580	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GUU85_RS01585	ENOG4108ZC9	flagellar basal-body rod protein flgc
GUU85_RS01590	ENOG4105W00	Flagellar hook capping protein
GUU85_RS01595	ENOG4105BZE	flagellar hook protein, FlgE
GUU85_RS01600	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GUU85_RS01605	ENOG4105CGA	flagellar basal-body rod protein FlgG
GUU85_RS01615	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GUU85_RS01625	ENOG4105E1Q	flagellar hook-associated protein
GUU85_RS01630	ENOG4107QQB	Ribonuclease E
GUU85_RS01635	ENOG4105EI2	Pseudouridine synthase
GUU85_RS01640	ENOG4105VGS	50s ribosomal protein l32
GUU85_RS01645	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GUU85_RS01650	ENOG4105CHR	reductase
GUU85_RS01660	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GUU85_RS01670	ENOG4105F8V	Hydrolase, tatD family
GUU85_RS01675	ENOG4105CI1	PTS System
GUU85_RS01680	ENOG4105K59	histidine triad (HIT) protein
GUU85_RS01685	ENOG4108742	Forms pores that allow passive diffusion of small molecules across the membrane (By similarity)
GUU85_RS01690	ENOG4105C5S	asparaginyl-tRNA synthetase
GUU85_RS01700	ENOG4105C5H	ABC transporter
GUU85_RS01710	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GUU85_RS01715	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GUU85_RS01720	ENOG4105DBV	ornithine carbamoyltransferase
GUU85_RS01725	ENOG4105KME	endoribonuclease L-psp
GUU85_RS01730	ENOG4105C1J	atp-dependent rna helicase
GUU85_RS01745	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GUU85_RS01750	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GUU85_RS01760	ENOG4105CHV	Transcription elongation factor NusA
GUU85_RS01780	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GUU85_RS01785	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GUU85_RS01795	ENOG4105VFK	BolA family
GUU85_RS01830	ENOG4105CQC	Prephenate dehydratase
GUU85_RS01835	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GUU85_RS01845	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GUU85_RS01850	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GUU85_RS01860	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GUU85_RS01875	ENOG4105C34	Pseudouridine synthase
GUU85_RS01880	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GUU85_RS01885	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GUU85_RS01890	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GUU85_RS01905	ENOG4105D9M	gamma-glutamylcysteine synthetase
GUU85_RS01910	ENOG4105RWS	endonuclease I
GUU85_RS01915	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GUU85_RS01955	ENOG4108K5P	(LipO)protein
GUU85_RS01965	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GUU85_RS01975	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GUU85_RS01990	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GUU85_RS02005	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GUU85_RS02010	ENOG4108Z33	Thiol disulfide Interchange Protein
GUU85_RS02015	ENOG4105C2M	dna polymerase I
GUU85_RS02025	ENOG4105CI3	gtp-binding protein typa
GUU85_RS02030	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GUU85_RS02035	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GUU85_RS02045	ENOG4105CRK	lysyL-tRNA synthetase
GUU85_RS02050	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GUU85_RS02065	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GUU85_RS02070	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GUU85_RS02075	ENOG4108JU5	Magnesium and cobalt efflux protein
GUU85_RS02080	ENOG4105C8T	Leucyl-tRNA synthetase
GUU85_RS02100	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GUU85_RS02105	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GUU85_RS02115	ENOG4105D2N	Aldolase
GUU85_RS02120	ENOG4105D64	Mechanosensitive ion channel
GUU85_RS02125	ENOG4105DSY	exodeoxyribonuclease V, gamma
GUU85_RS02130	ENOG4107QKA	exodeoxyribonuclease V beta
GUU85_RS02135	ENOG4107QYX	exodeoxyribonuclease v alpha
GUU85_RS02145	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GUU85_RS02155	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GUU85_RS02160	ENOG4108DQE	riboflavin reductase
GUU85_RS02175	ENOG4105CTB	Polyprenyl synthetase
GUU85_RS02180	ENOG4107RDB	Major Facilitator
GUU85_RS02185	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GUU85_RS02195	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GUU85_RS02200	ENOG4107R3R	Cytochrome o ubiquinol oxidase subunit III
GUU85_RS02205	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GUU85_RS02210	ENOG4105E2S	oxidase) subunit II
GUU85_RS02215	ENOG4105M85	Bola protein
GUU85_RS02225	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GUU85_RS02235	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GUU85_RS02240	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GUU85_RS02245	ENOG4105BZ1	(ABC) transporter
GUU85_RS02250	ENOG4105BZ1	(ABC) transporter
GUU85_RS02260	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GUU85_RS02265	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GUU85_RS02270	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GUU85_RS02285	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GUU85_RS02300	ENOG4105VEQ	Cold shock protein
GUU85_RS02325	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GUU85_RS02350	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GUU85_RS02370	ENOG41087H9	50S ribosomal protein L36
GUU85_RS02375	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GUU85_RS02390	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GUU85_RS02400	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GUU85_RS02410	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GUU85_RS02415	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GUU85_RS02420	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GUU85_RS02435	ENOG41083MP	50s ribosomal protein l29
GUU85_RS02460	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GUU85_RS02475	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GUU85_RS02520	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GUU85_RS02530	ENOG4105C31	Tryptophanyl-tRNA synthetase
GUU85_RS02535	ENOG4105DJV	ribulose-phosphate 3-epimerase
GUU85_RS02540	ENOG4105D49	3-dehydroquinate synthase
GUU85_RS02545	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GUU85_RS02570	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GUU85_RS02575	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GUU85_RS02580	ENOG4108UUM	single-stranded DNA-binding protein
GUU85_RS02585	ENOG4105CDU	Replicative dna helicase
GUU85_RS02590	ENOG4105D7Z	glutathione synthase
GUU85_RS02600	ENOG4105CSA	Coproporphyrinogen iii oxidase
GUU85_RS02610	ENOG4105CEN	a g-specific adenine glycosylase
GUU85_RS02615	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GUU85_RS02620	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GUU85_RS02625	ENOG4105CJB	Exodeoxyribonuclease I
GUU85_RS02655	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GUU85_RS02675	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GUU85_RS02685	ENOG4105EPW	hflc protein
GUU85_RS02690	ENOG4107QJR	hflk protein
GUU85_RS02695	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GUU85_RS02705	ENOG4105CTS	PTS system mannitol-specific
GUU85_RS02715	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GUU85_RS02725	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GUU85_RS02735	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GUU85_RS02745	ENOG4108ZNX	Heat shock protein
GUU85_RS02750	ENOG4105DP0	ferredoxin-NADP reductase
GUU85_RS02775	ENOG4105CJ3	phosphate transporter
GUU85_RS02780	ENOG4105D94	Major Facilitator Superfamily
GUU85_RS02820	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GUU85_RS02825	ENOG4105K63	Thioredoxin
GUU85_RS02830	ENOG4105C4R	Atp-dependent dna helicase
GUU85_RS02855	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GUU85_RS02870	ENOG4108ZIT	Ferredoxin, 2FE-2S