locus-tag	class	description
GUU85_RS00010	COG0356	it plays a direct role in the translocation of protons across the membrane
GUU85_RS00020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GUU85_RS00050	COG0187	DNA topoisomerase II activity
GUU85_RS00055	COG0592	DNA-directed DNA polymerase activity
GUU85_RS00060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GUU85_RS00065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GUU85_RS00070	COG0594	ribonuclease P activity
GUU85_RS00100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GUU85_RS00105	COG1484	DNA-dependent DNA replication
GUU85_RS00115	COG0742	ribosomal rna small subunit methyltransferase
GUU85_RS00120	COG0552	protein localization to endoplasmic reticulum
GUU85_RS00125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GUU85_RS00130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GUU85_RS00140	COG0561	phosphatase activity
GUU85_RS00145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GUU85_RS00155	COG0776	regulation of translation
GUU85_RS00160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GUU85_RS00190	COG0250	Participates in transcription elongation, termination and antitermination
GUU85_RS00195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GUU85_RS00220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GUU85_RS00225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GUU85_RS00235	COG0165	Argininosuccinate lyase
GUU85_RS00240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GUU85_RS00250	COG1045	serine acetyltransferase
GUU85_RS00255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GUU85_RS00260	COG0358	DNA primase activity
GUU85_RS00265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GUU85_RS00280	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GUU85_RS00295	COG2190	(PTS) system
GUU85_RS00300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GUU85_RS00305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GUU85_RS00310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GUU85_RS00330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GUU85_RS00340	COG1677	Flagellar hook-basal body complex protein FliE
GUU85_RS00345	COG1766	The M ring may be actively involved in energy transduction
GUU85_RS00350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GUU85_RS00355	COG1317	bacterial-type flagellum organization
GUU85_RS00360	COG1157	protein secretion by the type III secretion system
GUU85_RS00375	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GUU85_RS00380	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GUU85_RS00385	COG3190	flagellar
GUU85_RS00385	COG1338	Plays a role in the flagellum-specific transport system
GUU85_RS00390	COG1987	bacterial-type flagellum assembly
GUU85_RS00395	COG1684	flagellar biosynthetic protein fliR
GUU85_RS00400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GUU85_RS00405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GUU85_RS00410	COG2911	Protein conserved in bacteria
GUU85_RS00415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GUU85_RS00420	COG0312	modulator of DNA gyrase
GUU85_RS00430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GUU85_RS00435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GUU85_RS00445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GUU85_RS00450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GUU85_RS00480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GUU85_RS00485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GUU85_RS00495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GUU85_RS00505	COG0107	imidazoleglycerol-phosphate synthase activity
GUU85_RS00510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GUU85_RS00510	COG0140	phosphoribosyl-ATP diphosphatase activity
GUU85_RS00515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GUU85_RS00520	COG0717	Belongs to the dCTP deaminase family
GUU85_RS00540	COG0307	riboflavin synthase, alpha
GUU85_RS00545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GUU85_RS00550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GUU85_RS00560	COG0316	Belongs to the HesB IscA family
GUU85_RS00565	COG0628	permease
GUU85_RS00570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GUU85_RS00575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GUU85_RS00585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GUU85_RS00595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GUU85_RS00600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GUU85_RS00600	COG0072	phenylalanine-tRNA ligase activity
GUU85_RS00615	COG1862	Preprotein translocase
GUU85_RS00640	COG0586	Pfam SNARE associated Golgi protein
GUU85_RS00645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GUU85_RS00650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GUU85_RS00655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GUU85_RS00660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GUU85_RS00665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GUU85_RS00670	COG0505	Belongs to the CarA family
GUU85_RS00690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GUU85_RS00695	COG0196	riboflavin kinase activity
GUU85_RS00715	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GUU85_RS00725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GUU85_RS00725	COG0649	NAD binding
GUU85_RS00730	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GUU85_RS00735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GUU85_RS00740	COG1034	ATP synthesis coupled electron transport
GUU85_RS00750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GUU85_RS00755	COG0839	Belongs to the complex I subunit 6 family
GUU85_RS00765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GUU85_RS00770	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GUU85_RS00775	COG1007	ATP synthesis coupled electron transport
GUU85_RS00780	COG0285	dihydrofolate synthase activity
GUU85_RS00790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GUU85_RS00795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GUU85_RS00805	COG2890	protein-(glutamine-N5) methyltransferase activity
GUU85_RS00810	COG2912	Transglutaminase-like superfamily
GUU85_RS00820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GUU85_RS00825	COG0280	phosphate acetyltransferase
GUU85_RS00825	COG0857	belongs to the CobB CobQ family
GUU85_RS00830	COG0633	Ferredoxin
GUU85_RS00835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GUU85_RS00840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GUU85_RS00845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GUU85_RS00850	COG3416	Protein conserved in bacteria
GUU85_RS00855	COG0450	alkyl hydroperoxide reductase
GUU85_RS00865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GUU85_RS00880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GUU85_RS00885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GUU85_RS00890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GUU85_RS00900	COG0012	GTP binding
GUU85_RS00905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GUU85_RS00915	COG0460	homoserine dehydrogenase
GUU85_RS00915	COG0527	aspartate kinase activity
GUU85_RS00920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GUU85_RS00925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GUU85_RS00935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GUU85_RS00945	COG0237	dephospho-CoA kinase activity
GUU85_RS00955	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GUU85_RS00960	COG0508	dehydrogenase complex catalyzes the overall conversion of
GUU85_RS00965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GUU85_RS00975	COG0316	Belongs to the HesB IscA family
GUU85_RS00980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GUU85_RS00985	COG0849	cell division
GUU85_RS00990	COG1181	Belongs to the D-alanine--D-alanine ligase family
GUU85_RS01005	COG0772	Belongs to the SEDS family
GUU85_RS01025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GUU85_RS01030	COG0768	penicillin binding
GUU85_RS01045	COG0440	acetolactate synthase activity
GUU85_RS01050	COG0028	Belongs to the TPP enzyme family
GUU85_RS01055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GUU85_RS01060	COG2171	N-acyltransferase activity
GUU85_RS01065	COG0024	Methionine aminopeptidase
GUU85_RS01080	COG0528	UMP kinase activity
GUU85_RS01090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GUU85_RS01095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GUU85_RS01100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GUU85_RS01120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GUU85_RS01125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GUU85_RS01150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GUU85_RS01155	COG0328	RNA-DNA hybrid ribonuclease activity
GUU85_RS01160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GUU85_RS01175	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GUU85_RS01180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GUU85_RS01190	COG0590	tRNA wobble adenosine to inosine editing
GUU85_RS01210	COG0681	Belongs to the peptidase S26 family
GUU85_RS01220	COG0482	sulfurtransferase activity
GUU85_RS01225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GUU85_RS01230	COG0741	lytic transglycosylase activity
GUU85_RS01235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GUU85_RS01245	COG2095	MarC family integral membrane protein
GUU85_RS01250	COG0321	lipoyl(octanoyl) transferase activity
GUU85_RS01265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GUU85_RS01275	COG1607	acyl-coa hydrolase
GUU85_RS01280	COG2917	probably involved in intracellular septation
GUU85_RS01295	COG0133	tryptophan synthase activity
GUU85_RS01300	COG0135	phosphoribosylanthranilate isomerase activity
GUU85_RS01300	COG0134	indole-3-glycerol-phosphate synthase activity
GUU85_RS01310	COG0697	spore germination
GUU85_RS01315	COG1187	pseudouridine synthase activity
GUU85_RS01320	COG0616	signal peptide processing
GUU85_RS01325	COG0483	inositol monophosphate 1-phosphatase activity
GUU85_RS01330	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GUU85_RS01335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GUU85_RS01340	COG0124	histidyl-tRNA synthetase
GUU85_RS01355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GUU85_RS01360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GUU85_RS01365	COG2706	6-phosphogluconolactonase activity
GUU85_RS01370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GUU85_RS01375	COG4591	ABC-type transport system involved in lipoprotein release permease component
GUU85_RS01380	COG1136	(ABC) transporter
GUU85_RS01390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GUU85_RS01395	COG0716	FMN binding
GUU85_RS01400	COG0415	Belongs to the DNA photolyase family
GUU85_RS01405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GUU85_RS01410	COG0567	Dehydrogenase, E1 component
GUU85_RS01415	COG0508	dehydrogenase complex catalyzes the overall conversion of
GUU85_RS01430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GUU85_RS01435	COG0149	triose-phosphate isomerase activity
GUU85_RS01445	COG0539	negative regulation of cytoplasmic translation
GUU85_RS01465	COG0492	ferredoxin-NADP+ reductase activity
GUU85_RS01470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GUU85_RS01475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GUU85_RS01480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GUU85_RS01485	COG1121	(ABC) transporter
GUU85_RS01490	COG0469	pyruvate kinase activity
GUU85_RS01495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GUU85_RS01505	COG1278	Cold shock
GUU85_RS01510	COG1253	flavin adenine dinucleotide binding
GUU85_RS01525	COG2894	cell division
GUU85_RS01535	COG2813	Specifically methylates the guanine in position
GUU85_RS01540	COG2813	Specifically methylates the guanine in position
GUU85_RS01560	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GUU85_RS01560	COG2885	chlorophyll binding
GUU85_RS01565	COG0728	peptidoglycan biosynthetic process
GUU85_RS01570	COG3418	PFAM FlgN family protein
GUU85_RS01575	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GUU85_RS01580	COG1815	bacterial-type flagellum-dependent cell motility
GUU85_RS01585	COG1558	bacterial-type flagellum-dependent cell motility
GUU85_RS01590	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GUU85_RS01595	COG1749	Flagellar hook protein flgE
GUU85_RS01600	COG4787	bacterial-type flagellum-dependent cell motility
GUU85_RS01605	COG4786	Flagellar basal body rod
GUU85_RS01615	COG1706	bacterial-type flagellum-dependent cell motility
GUU85_RS01620	COG3951	Flagellar rod assembly protein muramidase FlgJ
GUU85_RS01625	COG1256	bacterial-type flagellum assembly
GUU85_RS01630	COG1530	ribonuclease E activity
GUU85_RS01635	COG0564	pseudouridine synthase activity
GUU85_RS01635	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GUU85_RS01640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GUU85_RS01645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GUU85_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
GUU85_RS01660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GUU85_RS01670	COG0084	hydrolase, TatD family'
GUU85_RS01675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GUU85_RS01675	COG1263	PTS System
GUU85_RS01680	COG0537	adenosine 5'-monophosphoramidase activity
GUU85_RS01685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GUU85_RS01690	COG0017	Asparaginyl-tRNA synthetase
GUU85_RS01700	COG0488	(ABC) transporter
GUU85_RS01710	COG0525	valine-tRNA ligase activity
GUU85_RS01715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GUU85_RS01720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GUU85_RS01725	COG0251	oxidation-reduction process
GUU85_RS01730	COG0513	Belongs to the DEAD box helicase family
GUU85_RS01745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GUU85_RS01750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GUU85_RS01760	COG0195	Participates in both transcription termination and antitermination
GUU85_RS01770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GUU85_RS01780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GUU85_RS01785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GUU85_RS01795	COG5007	Belongs to the BolA IbaG family
GUU85_RS01830	COG0077	Prephenate dehydratase
GUU85_RS01830	COG1605	Chorismate mutase
GUU85_RS01835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GUU85_RS01845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GUU85_RS01850	COG0336	Belongs to the RNA methyltransferase TrmD family
GUU85_RS01860	COG0312	modulator of DNA gyrase
GUU85_RS01875	COG0564	pseudouridine synthase activity
GUU85_RS01880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GUU85_RS01885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GUU85_RS01890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GUU85_RS01905	COG2918	glutathione biosynthetic process
GUU85_RS01910	COG2356	endonuclease I
GUU85_RS01915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GUU85_RS01955	COG1388	LysM domain
GUU85_RS01955	COG0739	heme binding
GUU85_RS01965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GUU85_RS01970	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GUU85_RS01975	COG0529	Catalyzes the synthesis of activated sulfate
GUU85_RS01990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GUU85_RS01990	COG1648	precorrin-2 dehydrogenase activity
GUU85_RS02005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GUU85_RS02010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GUU85_RS02015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GUU85_RS02030	COG0194	GDP metabolic process
GUU85_RS02035	COG0354	folic acid binding
GUU85_RS02045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GUU85_RS02050	COG0019	diaminopimelate decarboxylase activity
GUU85_RS02065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GUU85_RS02070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GUU85_RS02075	COG4535	Mg2 and Co2 transporter CorC
GUU85_RS02080	COG0495	leucyl-tRNA aminoacylation
GUU85_RS02085	COG1466	dna polymerase III delta subunit
GUU85_RS02100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GUU85_RS02105	COG2095	MarC family integral membrane protein
GUU85_RS02115	COG0191	fructose-bisphosphate aldolase activity
GUU85_RS02120	COG0668	transmembrane transport
GUU85_RS02125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GUU85_RS02130	COG1074	ATP-dependent DNA helicase activity
GUU85_RS02135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GUU85_RS02145	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GUU85_RS02155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GUU85_RS02160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GUU85_RS02175	COG0142	geranyltranstransferase activity
GUU85_RS02180	COG2814	Major facilitator Superfamily
GUU85_RS02185	COG2920	part of a sulfur-relay system
GUU85_RS02195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GUU85_RS02200	COG1845	cytochrome c oxidase, subunit III
GUU85_RS02205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GUU85_RS02210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GUU85_RS02215	COG0271	Belongs to the BolA IbaG family
GUU85_RS02225	COG0740	serine-type endopeptidase activity
GUU85_RS02235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GUU85_RS02240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GUU85_RS02245	COG1132	(ABC) transporter
GUU85_RS02250	COG1132	(ABC) transporter
GUU85_RS02260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GUU85_RS02265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GUU85_RS02270	COG0326	Molecular chaperone. Has ATPase activity
GUU85_RS02285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GUU85_RS02300	COG1278	Cold shock
GUU85_RS02325	COG0009	L-threonylcarbamoyladenylate synthase
GUU85_RS02350	COG0202	RNA polymerase activity
GUU85_RS02370	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GUU85_RS02375	COG0201	protein transport
GUU85_RS02390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GUU85_RS02400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GUU85_RS02410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GUU85_RS02415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GUU85_RS02420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GUU85_RS02435	COG0255	Belongs to the universal ribosomal protein uL29 family
GUU85_RS02460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GUU85_RS02475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GUU85_RS02520	COG0545	Peptidyl-prolyl cis-trans isomerase
GUU85_RS02530	COG0180	Tryptophanyl-tRNA synthetase
GUU85_RS02535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GUU85_RS02540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GUU85_RS02545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GUU85_RS02570	COG0316	Belongs to the HesB IscA family
GUU85_RS02570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GUU85_RS02575	COG2267	carboxylic ester hydrolase activity
GUU85_RS02580	COG0629	single-stranded DNA binding
GUU85_RS02585	COG0305	Participates in initiation and elongation during chromosome replication
GUU85_RS02590	COG0189	ligase activity
GUU85_RS02600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GUU85_RS02610	COG1194	a g-specific adenine glycosylase
GUU85_RS02615	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GUU85_RS02620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GUU85_RS02625	COG2925	Exonuclease
GUU85_RS02655	COG1218	3'(2'),5'-bisphosphate nucleotidase
GUU85_RS02675	COG0557	exoribonuclease II activity
GUU85_RS02685	COG0330	HflC and HflK could
GUU85_RS02690	COG0330	HflC and HflK could
GUU85_RS02695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GUU85_RS02705	COG2213	PTS system mannitol-specific
GUU85_RS02705	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GUU85_RS02715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GUU85_RS02725	COG0860	N-Acetylmuramoyl-L-alanine amidase
GUU85_RS02735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GUU85_RS02745	COG0071	Belongs to the small heat shock protein (HSP20) family
GUU85_RS02750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GUU85_RS02775	COG0306	phosphate transporter
GUU85_RS02780	COG2814	Major facilitator Superfamily
GUU85_RS02820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GUU85_RS02825	COG3118	belongs to the thioredoxin family
GUU85_RS02830	COG0210	DNA helicase
GUU85_RS02855	COG0822	iron-sulfur transferase activity
GUU85_RS02870	COG0633	Ferredoxin
GUU85_RS02880	COG2976	Protein conserved in bacteria