locus_tag old_locus_tag gene Name start end strand product note type ID NCBI C5S_RS01000000103180 C5S_RS01000000103180 C5S_RS01000000103180 65116 66063 - kinase gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS01000000103180 C5S_RS01000000103185 C5S_RS01000000103185 C5S_RS01000000103185 82201 82512 + hypothetical protein gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS01000000103185 C5S_RS01000000103200 C5S_RS01000000103200 C5S_RS01000000103200 251321 251920 - thiamine biosynthesis protein ApbE gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS01000000103200 C5S_RS01000000103210 C5S_RS01000000103210 C5S_RS01000000103210 425441 426103 - rRNA methyltransferase gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS01000000103210 C5S_RS0100010 C5S_RS0100010 C5S_RS0100010 202 2088 + tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100010 C5S_RS0100015 C5S_RS0100015 C5S_RS0100015 2283 3107 + ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100015 C5S_RS0100020 C5S_RS0100020 C5S_RS0100020 3144 3383 + ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100020 C5S_RS0100025 C5S_RS0100025 C5S_RS0100025 3502 3987 + ATP synthase subunit b Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100025 C5S_RS0100030 C5S_RS0100030 C5S_RS0100030 3987 4520 + ATP synthase subunit delta gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100030 C5S_RS0100035 C5S_RS0100035 C5S_RS0100035 4535 6073 + ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100035 C5S_RS0100040 C5S_RS0100040 C5S_RS0100040 6106 6978 + ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100040 C5S_RS0100045 C5S_RS0100045 C5S_RS0100045 7002 8399 + ATP synthase subunit beta gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100045 C5S_RS0100050 C5S_RS0100050 C5S_RS0100050 8420 8842 + ATP synthase F0F1 subunit epsilon gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100050 C5S_RS0100055 C5S_RS0100055 gyrB gyrB 8916 11327 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100055 C5S_RS0100060 C5S_RS0100060 C5S_RS0100060 11454 12554 - DNA polymerase III subunit beta gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100060 C5S_RS0100065 C5S_RS0100065 dnaA dnaA 12559 13923 - chromosomal replication initiator protein DnaA binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100065 C5S_RS0100070 C5S_RS0100070 rpmH rpmH 14374 14517 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100070 C5S_RS0100075 C5S_RS0100075 C5S_RS0100075 15015 16613 + protein translocase component YidC functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100075 C5S_RS0100080 C5S_RS0100080 C5S_RS0100080 16652 18013 + tRNA modification GTPase TrmE gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100080 C5S_RS0100085 C5S_RS0100085 C5S_RS0100085 18033 18105 - tRNA-Phe tRNA gene16 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100085 C5S_RS0100090 C5S_RS0100090 groES groES 18380 18670 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100090 C5S_RS0100095 C5S_RS0100095 groEL groEL 18719 20365 + molecular chaperone GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100095 C5S_RS0100100 C5S_RS0100100 C5S_RS0100100 21032 21601 + elongation factor P gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100100 C5S_RS0100105 C5S_RS0100105 C5S_RS0100105 21619 22359 - DNA replication protein DnaC acts to load the DnaB helicase onto the initiation site during DNA replication gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100105 C5S_RS0100110 C5S_RS0100110 C5S_RS0100110 22359 22853 - primosomal protein 1 gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100110 C5S_RS0100115 C5S_RS0100115 rsmD rsmD 22950 23525 - ribosomal RNA small subunit methyltransferase D catalyzes the methylation of 16S rRNA at position G966 gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100115 C5S_RS0100120 C5S_RS0100120 C5S_RS0100120 23656 24792 + signal recognition particle-docking protein FtsY gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100120 C5S_RS0100125 C5S_RS0100125 C5S_RS0100125 24955 25809 + RNA polymerase sigma factor RpoH binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100125 C5S_RS0100130 C5S_RS0100130 C5S_RS0100130 25950 27779 - glutamine--fructose-6-phosphate aminotransferase [isomerizing] Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100130 C5S_RS0100135 C5S_RS0100135 glmU glmU 27849 29228 - bifunctional protein GlmU forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100135 C5S_RS0100140 C5S_RS0100140 C5S_RS0100140 29408 30226 + hypothetical protein gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100140 C5S_RS0100145 C5S_RS0100145 C5S_RS0100145 31197 33473 + 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100145 C5S_RS0100150 C5S_RS0100150 purH purH 33596 35173 - bifunctional purine biosynthesis protein PurH involved in de novo purine biosynthesis gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100150 C5S_RS0100155 C5S_RS0100155 C5S_RS0100155 35314 35592 - transcriptional regulator gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100155 C5S_RS0100160 C5S_RS0100160 C5S_RS0100160 35944 36189 + hypothetical protein gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100160 C5S_RS0100165 C5S_RS0100165 C5S_RS0100165 36326 40549 - DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100165 C5S_RS0100170 C5S_RS0100170 rpoB rpoB 40627 44655 - DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100170 C5S_RS0100175 C5S_RS0100175 C5S_RS0100175 44875 45243 - 50S ribosomal protein L7/L12 gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100175 C5S_RS0100180 C5S_RS0100180 C5S_RS0100180 45310 45807 - 50S ribosomal protein L10 gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100180 C5S_RS0100185 C5S_RS0100185 C5S_RS0100185 46073 46768 - 50S ribosomal protein L1 gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100185 C5S_RS0100190 C5S_RS0100190 C5S_RS0100190 46771 47199 - 50S ribosomal protein L11 gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100190 C5S_RS0100195 C5S_RS0100195 nusG nusG 47247 47792 - transcription termination/antitermination protein NusG Modulates Rho-dependent transcription termination gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100195 C5S_RS0100200 C5S_RS0100200 C5S_RS0100200 47795 48178 - preprotein translocase subunit SecE gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100200 C5S_RS0100205 C5S_RS0100205 C5S_RS0100205 48491 48563 - tRNA-Thr tRNA gene40 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100205 C5S_RS0100210 C5S_RS0100210 C5S_RS0100210 48579 48650 - tRNA-Gly tRNA gene41 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100210 C5S_RS0100215 C5S_RS0100215 C5S_RS0100215 48673 48757 - tRNA-Tyr tRNA gene42 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100215 C5S_RS0100220 C5S_RS0100220 C5S_RS0100220 48773 48845 - tRNA-Thr tRNA gene43 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100220 C5S_RS0100225 C5S_RS0100225 murB murB 48983 50053 - UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100225 C5S_RS0100230 C5S_RS0100230 metF metF 50169 51047 + 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100230 C5S_RS0100235 C5S_RS0100235 C5S_RS0100235 51059 52204 - acetylornithine deacetylase catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100235 C5S_RS0100240 C5S_RS0100240 C5S_RS0100240 52365 53369 + N-acetyl-gamma-glutamyl-phosphate reductase gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100240 C5S_RS0100245 C5S_RS0100245 C5S_RS0100245 53390 54163 + acetylglutamate kinase gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100245 C5S_RS0100250 C5S_RS0100250 C5S_RS0100250 54193 55404 + argininosuccinate synthase gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100250 C5S_RS0100255 C5S_RS0100255 C5S_RS0100255 55476 56855 + argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100255 C5S_RS0100260 C5S_RS0100260 C5S_RS0100260 56937 57371 + hypothetical protein gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100260 C5S_RS0100265 C5S_RS0100265 C5S_RS0100265 57479 57907 + protein-export protein SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100265 C5S_RS0100270 C5S_RS0100270 cysE cysE 58009 58833 + serine acetyltransferase catalyzes the O-acetylation of serine gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100270 C5S_RS0100275 C5S_RS0100275 C5S_RS0100275 58940 60778 - RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100275 C5S_RS0100280 C5S_RS0100280 dnaG dnaG 60946 62679 - DNA primase synthesizes RNA primers at the replication forks gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100280 C5S_RS0100285 C5S_RS0100285 rpsU rpsU 62760 62975 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100285 C5S_RS0100290 C5S_RS0100290 C5S_RS0100290 63209 64219 + tRNA N6-adenosine threonylcarbamoyltransferase gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100290 C5S_RS0100295 C5S_RS0100295 ribB ribB 64197 64844 - 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100295 C5S_RS0100305 C5S_RS0100305 C5S_RS0100305 66277 67521 + CCA-adding enzyme catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA%3B these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100305 C5S_RS0100310 C5S_RS0100310 C5S_RS0100310 67547 68344 - undecaprenyl-diphosphatase gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100310 C5S_RS0100315 C5S_RS0100315 C5S_RS0100315 68430 68915 - PTS glucose transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100315 C5S_RS0100320 C5S_RS0100320 C5S_RS0100320 68965 70680 - phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100320 C5S_RS0100325 C5S_RS0100325 C5S_RS0100325 70829 71086 - phosphocarrier protein HPr gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100325 C5S_RS0100330 C5S_RS0100330 C5S_RS0100330 71236 72183 - cysteine synthase gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100330 C5S_RS0100335 C5S_RS0100335 C5S_RS0100335 72438 74465 + DNA ligase gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100335 C5S_RS0100340 C5S_RS0100340 C5S_RS0100340 74478 74550 - tRNA-Lys tRNA gene67 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100340 C5S_RS0100345 C5S_RS0100345 C5S_RS0100345 74579 74651 - tRNA-Val tRNA gene68 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100345 C5S_RS0100350 C5S_RS0100350 C5S_RS0100350 74777 76180 + glutamate--tRNA ligase gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100350 C5S_RS0100355 C5S_RS0100355 C5S_RS0100355 76355 76430 + tRNA-Ala tRNA gene70 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100355 C5S_RS0100360 C5S_RS0100360 C5S_RS0100360 76520 76816 - flagellar hook-basal body complex protein FliE gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100360 C5S_RS0100365 C5S_RS0100365 C5S_RS0100365 77080 78717 + flagellar M-ring protein FliF gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100365 C5S_RS0100370 C5S_RS0100370 C5S_RS0100370 78714 79709 + flagellar motor switch protein FliG gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100370 C5S_RS0100375 C5S_RS0100375 C5S_RS0100375 79702 80364 + flagellar assembly protein FliH gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100375 C5S_RS0100380 C5S_RS0100380 fliI fliI 80322 81725 + flagellum-specific ATP synthase involved in type III protein export during flagellum assembly gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100380 C5S_RS0100385 C5S_RS0100385 C5S_RS0100385 81755 82192 + flagellar FliJ protein gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100385 C5S_RS0100395 C5S_RS0100395 C5S_RS0100395 82546 83337 + flagellar hook-length control protein gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100395 C5S_RS0100400 C5S_RS0100400 C5S_RS0100400 83443 84345 + flagellar motor switch protein FliM gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100400 C5S_RS0100405 C5S_RS0100405 C5S_RS0100405 84338 84739 + flagellar motor switch protein FliN gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100405 C5S_RS0100410 C5S_RS0100410 C5S_RS0100410 85156 85890 + hypothetical protein gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100410 C5S_RS0100415 C5S_RS0100415 C5S_RS0100415 85962 86231 + flagellar biosynthetic protein FliQ gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100415 C5S_RS0100420 C5S_RS0100420 fliR fliR 86231 87007 + flagellar biosynthesis protein FliR FliR%2C with proteins FliP and FliQ%2C forms the core of the central channel in the flagella export apparatus gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100420 C5S_RS0100425 C5S_RS0100425 rpmG rpmG 87160 87327 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100425 C5S_RS0100430 C5S_RS0100430 C5S_RS0100430 87338 87565 - 50S ribosomal protein L28 gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100430 C5S_RS0100440 C5S_RS0100440 C5S_RS0100440 87911 90823 + hypothetical protein gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100440 C5S_RS0100445 C5S_RS0100445 C5S_RS0100445 90839 91387 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100445 C5S_RS0100450 C5S_RS0100450 pmbA pmbA 91581 92921 + peptidase PMbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100450 C5S_RS0100455 C5S_RS0100455 C5S_RS0100455 93399 94247 - ribosomal RNA small subunit methyltransferase I gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100455 C5S_RS0100460 C5S_RS0100460 C5S_RS0100460 94386 95606 + 3-oxoacyl-ACP synthase I gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100460 C5S_RS0100465 C5S_RS0100465 C5S_RS0100465 95846 96796 + transaldolase gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100465 C5S_RS0100470 C5S_RS0100470 C5S_RS0100470 96851 98848 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100470 C5S_RS0100475 C5S_RS0100475 C5S_RS0100475 98953 100080 + succinyl-diaminopimelate desuccinylase gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100475 C5S_RS0100480 C5S_RS0100480 C5S_RS0100480 100238 100492 - hypothetical protein gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100480 C5S_RS0100485 C5S_RS0100485 C5S_RS0100485 100470 101354 - 4-hydroxy-tetrahydrodipicolinate synthase gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100485 C5S_RS0100490 C5S_RS0100490 C5S_RS0100490 101930 102994 - chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100490 C5S_RS0100495 C5S_RS0100495 C5S_RS0100495 103056 103259 + hypothetical protein gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100495 C5S_RS0100500 C5S_RS0100500 C5S_RS0100500 103289 103849 + hypothetical protein gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100500 C5S_RS0100505 C5S_RS0100505 hisG hisG 104174 105073 + ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100505 C5S_RS0100510 C5S_RS0100510 hisD hisD 105082 106389 + histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100510 C5S_RS0100515 C5S_RS0100515 C5S_RS0100515 106386 107492 + histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100515 C5S_RS0100520 C5S_RS0100520 C5S_RS0100520 107482 108543 + histidine biosynthesis bifunctional protein HisB catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100520 C5S_RS0100525 C5S_RS0100525 C5S_RS0100525 108543 109133 + imidazole glycerol phosphate synthase subunit HisH gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100525 C5S_RS0100530 C5S_RS0100530 C5S_RS0100530 109138 109878 + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100530 C5S_RS0100535 C5S_RS0100535 C5S_RS0100535 109857 110633 + imidazole glycerol phosphate synthase subunit HisF gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100535 C5S_RS0100540 C5S_RS0100540 C5S_RS0100540 110627 111274 + phosphoribosyl-AMP cyclohydrolase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100540 C5S_RS0100545 C5S_RS0100545 C5S_RS0100545 111633 113039 + 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100545 C5S_RS0100550 C5S_RS0100550 C5S_RS0100550 113241 113822 + deoxycytidine triphosphate deaminase gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100550 C5S_RS0100555 C5S_RS0100555 C5S_RS0100555 113970 115613 + methionine--tRNA ligase gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100555 C5S_RS0100560 C5S_RS0100560 C5S_RS0100560 115661 116983 - tRNA(Ile)-lysidine synthetase gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100560 C5S_RS0100565 C5S_RS0100565 C5S_RS0100565 117013 117086 - tRNA-Val tRNA gene112 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100565 C5S_RS0100570 C5S_RS0100570 C5S_RS0100570 117209 117835 + riboflavin synthase subunit alpha gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100570 C5S_RS0100575 C5S_RS0100575 C5S_RS0100575 117872 118453 + electron transport complex subunit A gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100575 C5S_RS0100580 C5S_RS0100580 C5S_RS0100580 118456 118959 + electron transport complex subunit B gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100580 C5S_RS0100590 C5S_RS0100590 C5S_RS0100590 119122 120543 + electron transporter RnfC gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100590 C5S_RS0100595 C5S_RS0100595 C5S_RS0100595 120636 121634 + electron transporter RnfD gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100595 C5S_RS0100605 C5S_RS0100605 C5S_RS0100605 121873 122277 + electron transporter RnfG gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100605 C5S_RS0100610 C5S_RS0100610 C5S_RS0100610 122252 122935 + electron transport complex subunit E gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100610 C5S_RS0100615 C5S_RS0100615 C5S_RS0100615 122946 123578 + endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100615 C5S_RS0100620 C5S_RS0100620 C5S_RS0100620 123601 125781 + primosomal protein N' gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100620 C5S_RS0100625 C5S_RS0100625 C5S_RS0100625 125941 127209 + tyrosine--tRNA ligase gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100625 C5S_RS0100630 C5S_RS0100630 C5S_RS0100630 127217 127609 - hypothetical protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100630 C5S_RS0100635 C5S_RS0100635 C5S_RS0100635 127833 128915 + membrane protein YdiK%3B inner membrane protein%3B ydiK promoter presents a PurR sequence%2C suggesting that its expression is purine-regulated%3B unknown function gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100635 C5S_RS0100640 C5S_RS0100640 C5S_RS0100640 129267 130313 + phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100640 C5S_RS0100645 C5S_RS0100645 thrS thrS 130481 132409 + threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100645 C5S_RS0100650 C5S_RS0100650 C5S_RS0100650 132413 132952 + translation initiation factor IF-3 gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100650 C5S_RS0100655 C5S_RS0100655 C5S_RS0100655 133039 133236 + 50S ribosomal protein L35 gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100655 C5S_RS0100660 C5S_RS0100660 rplT rplT 133279 133635 + 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100660 C5S_RS0100665 C5S_RS0100665 C5S_RS0100665 133830 134819 + phenylalanyl-tRNA synthetase subunit alpha gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100665 C5S_RS0100670 C5S_RS0100670 C5S_RS0100670 134829 137216 + phenylalanine--tRNA ligase subunit beta gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100670 C5S_RS0100675 C5S_RS0100675 C5S_RS0100675 137221 137529 + integration host factor subunit alpha gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100675 C5S_RS0100680 C5S_RS0100680 queA queA 137571 138644 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100680 C5S_RS0100685 C5S_RS0100685 tgt tgt 138685 139797 + queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100685 C5S_RS0100690 C5S_RS0100690 yajC yajC 139822 140157 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100690 C5S_RS0100695 C5S_RS0100695 C5S_RS0100695 140209 142281 - glycine--tRNA ligase subunit beta gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100695 C5S_RS0100700 C5S_RS0100700 C5S_RS0100700 142256 143194 - glycine--tRNA ligase subunit alpha gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100700 C5S_RS0100705 C5S_RS0100705 C5S_RS0100705 143890 144735 + endonuclease Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100705 C5S_RS0100710 C5S_RS0100710 C5S_RS0100710 144770 145057 + 50S ribosomal protein L25 the Ctc family of proteins consists of two types%2C one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100710 C5S_RS0100715 C5S_RS0100715 C5S_RS0100715 145127 145897 - membrane protein gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100715 C5S_RS0100720 C5S_RS0100720 C5S_RS0100720 146084 147376 + peptidyl-prolyl cis-trans isomerase gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100720 C5S_RS0100725 C5S_RS0100725 C5S_RS0100725 147325 148251 + dimethyladenosine transferase gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100725 C5S_RS0100730 C5S_RS0100730 C5S_RS0100730 148296 149120 + bis(5'-nucleosyl)-tetraphosphatase symmetrical gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100730 C5S_RS0100735 C5S_RS0100735 C5S_RS0100735 149147 149632 - dihydrofolate reductase gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100735 C5S_RS0100740 C5S_RS0100740 carB carB 149722 152961 - carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100740 C5S_RS0100745 C5S_RS0100745 C5S_RS0100745 152975 154138 - carbamoyl phosphate synthase small subunit catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100745 C5S_RS0100750 C5S_RS0100750 C5S_RS0100750 154348 155157 - 4-hydroxy-tetrahydrodipicolinate reductase gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100750 C5S_RS0100755 C5S_RS0100755 ispH ispH 155161 156120 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100755 C5S_RS0100760 C5S_RS0100760 C5S_RS0100760 156185 156667 - lipoprotein signal peptidase gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100760 C5S_RS0100765 C5S_RS0100765 C5S_RS0100765 156667 159489 - isoleucine--tRNA ligase gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100765 C5S_RS0100770 C5S_RS0100770 C5S_RS0100770 159506 160447 - riboflavin biosynthesis protein RibF gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100770 C5S_RS0100780 C5S_RS0100780 rpsT rpsT 160662 160931 + 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100780 C5S_RS0100785 C5S_RS0100785 C5S_RS0100785 160981 162114 - molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100785 C5S_RS0100790 C5S_RS0100790 dnaK dnaK 162227 164140 - molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100790 C5S_RS0100795 C5S_RS0100795 C5S_RS0100795 164476 164880 + NADH-quinone oxidoreductase subunit A gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100795 C5S_RS0100800 C5S_RS0100800 C5S_RS0100800 164914 165588 + NADH-quinone oxidoreductase subunit B gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100800 C5S_RS0100805 C5S_RS0100805 C5S_RS0100805 165679 167481 + NADH-quinone oxidoreductase subunit C/D NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100805 C5S_RS0100810 C5S_RS0100810 C5S_RS0100810 167504 167992 + NADH-quinone oxidoreductase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100810 C5S_RS0100815 C5S_RS0100815 C5S_RS0100815 167989 169323 + NADH-quinone oxidoreductase subunit F part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100815 C5S_RS0100820 C5S_RS0100820 C5S_RS0100820 169417 172137 + NADH dehydrogenase subunit G Catalyzes the transfer of electrons from NADH to quinone gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100820 C5S_RS0100825 C5S_RS0100825 C5S_RS0100825 172149 173117 + NADH-quinone oxidoreductase subunit H gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100825 C5S_RS0100830 C5S_RS0100830 C5S_RS0100830 173142 173684 + NADH dehydrogenase subunit I gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100830 C5S_RS0100835 C5S_RS0100835 C5S_RS0100835 173694 174206 + NADH-quinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100835 C5S_RS0100840 C5S_RS0100840 C5S_RS0100840 174237 174539 + NADH-quinone oxidoreductase subunit K gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100840 C5S_RS0100845 C5S_RS0100845 C5S_RS0100845 174536 176380 + NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100845 C5S_RS0100850 C5S_RS0100850 C5S_RS0100850 176477 177994 + NADH:ubiquinone oxidoreductase subunit M gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100850 C5S_RS0100855 C5S_RS0100855 C5S_RS0100855 178001 179461 + NADH:ubiquinone oxidoreductase subunit N gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100855 C5S_RS0100860 C5S_RS0100860 C5S_RS0100860 180586 181821 + dihydrofolate synthase gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100860 C5S_RS0100865 C5S_RS0100865 C5S_RS0100865 181859 182086 + hypothetical protein gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100865 C5S_RS0100870 C5S_RS0100870 C5S_RS0100870 182107 182322 + hypothetical protein gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100870 C5S_RS0100875 C5S_RS0100875 C5S_RS0100875 182400 183347 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100875 C5S_RS0100880 C5S_RS0100880 C5S_RS0100880 183467 184351 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100880 C5S_RS0100885 C5S_RS0100885 prfA prfA 184559 185644 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100885 C5S_RS0100890 C5S_RS0100890 C5S_RS0100890 185641 186474 + release factor glutamine methyltransferase gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100890 C5S_RS0100895 C5S_RS0100895 C5S_RS0100895 186634 187443 + transcriptional regulator gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100895 C5S_RS0100900 C5S_RS0100900 nadE nadE 187451 188257 - nH(3)-dependent NAD+ synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100900 C5S_RS0100905 C5S_RS0100905 C5S_RS0100905 188341 189558 + acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100905 C5S_RS0100910 C5S_RS0100910 C5S_RS0100910 189603 191729 + phosphate acetyltransferase gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100910 C5S_RS0100915 C5S_RS0100915 C5S_RS0100915 191761 192024 - (2Fe-2S)-binding protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100915 C5S_RS0100920 C5S_RS0100920 C5S_RS0100920 192027 193157 - ribonucleoside-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100920 C5S_RS0100925 C5S_RS0100925 C5S_RS0100925 193225 195510 - ribonucleoside-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100925 C5S_RS0100930 C5S_RS0100930 C5S_RS0100930 195583 198075 - DNA gyrase subunit A gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100930 C5S_RS0100935 C5S_RS0100935 C5S_RS0100935 198347 199063 + hypothetical protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100935 C5S_RS0100940 C5S_RS0100940 C5S_RS0100940 199185 199778 - peroxiredoxin gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100940 C5S_RS0100945 C5S_RS0100945 C5S_RS0100945 199875 200516 + uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100945 C5S_RS0100950 C5S_RS0100950 C5S_RS0100950 200592 201158 - co-chaperone GrpE gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100950 C5S_RS0100955 C5S_RS0100955 ppnK ppnK 201275 202153 + NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100955 C5S_RS0100960 C5S_RS0100960 C5S_RS0100960 202286 202594 + outer membrane protein assembly factor BamE gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100960 C5S_RS0100965 C5S_RS0100965 C5S_RS0100965 203131 203457 + glutaredoxin gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100965 C5S_RS0100970 C5S_RS0100970 C5S_RS0100970 203601 204266 - ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100970 C5S_RS0100975 C5S_RS0100975 C5S_RS0100975 204486 205097 + superoxide dismutase [Mn] SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100975 C5S_RS0100980 C5S_RS0100980 C5S_RS0100980 205301 205834 + peptidyl-tRNA hydrolase gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100980 C5S_RS0100985 C5S_RS0100985 ychF ychF 205875 206963 + ribosome-binding ATPase YchF EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100985 C5S_RS0100990 C5S_RS0100990 C5S_RS0100990 207039 208328 - threonine synthase gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100990 C5S_RS0100995 C5S_RS0100995 C5S_RS0100995 208335 209264 - homoserine kinase gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0100995 C5S_RS0101000 C5S_RS0101000 thrA thrA 209285 211735 - bifunctional aspartokinase I/homoserine dehydrogenase I multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101000 C5S_RS0101005 C5S_RS0101005 C5S_RS0101005 212394 212930 + hypoxanthine phosphoribosyltransferase catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101005 C5S_RS0101010 C5S_RS0101010 panC panC 212938 213795 - pantothenate synthetase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101010 C5S_RS0101015 C5S_RS0101015 panB panB 213810 214601 - 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101015 C5S_RS0101020 C5S_RS0101020 dksA dksA 214717 215172 - transcriptional regulator gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101020 C5S_RS0101025 C5S_RS0101025 C5S_RS0101025 215429 216229 + tRNA pseudouridine synthase A gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101025 C5S_RS0101030 C5S_RS0101030 C5S_RS0101030 216301 218583 + bifunctional glycosyl transferase/transpeptidase gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101030 C5S_RS0101035 C5S_RS0101035 secA secA 218813 221440 + protein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101035 C5S_RS0101040 C5S_RS0101040 C5S_RS0101040 221516 221890 + DNA mismatch repair protein MutT gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101040 C5S_RS0101045 C5S_RS0101045 coaE coaE 221873 222526 - dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101045 C5S_RS0101050 C5S_RS0101050 C5S_RS0101050 222582 223631 + GMP reductase catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101050 C5S_RS0101055 C5S_RS0101055 aceE aceE 223859 226522 + pyruvate dehydrogenase E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101055 C5S_RS0101060 C5S_RS0101060 C5S_RS0101060 226553 227743 + dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101060 C5S_RS0101065 C5S_RS0101065 C5S_RS0101065 227787 229208 + dihydrolipoyl dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101065 C5S_RS0101070 C5S_RS0101070 C5S_RS0101070 229163 229351 - hypothetical protein gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101070 C5S_RS0101075 C5S_RS0101075 C5S_RS0101075 229381 230169 - S-adenosylmethionine decarboxylase S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101075 C5S_RS0101080 C5S_RS0101080 C5S_RS0101080 230197 231057 - polyamine aminopropyltransferase gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101080 C5S_RS0101085 C5S_RS0101085 C5S_RS0101085 231333 232031 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101085 C5S_RS0101090 C5S_RS0101090 C5S_RS0101090 232095 232439 - iron-sulfur cluster insertion protein ErpA gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101090 C5S_RS0101095 C5S_RS0101095 C5S_RS0101095 232673 233827 - peptidase M23 GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101095 C5S_RS0101100 C5S_RS0101100 ftsA ftsA 233885 235141 - cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101100 C5S_RS0101110 C5S_RS0101110 C5S_RS0101110 236256 237710 - UDP-N-acetylmuramate--L-alanine ligase gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101110 C5S_RS0101115 C5S_RS0101115 C5S_RS0101115 237753 238817 - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101115 C5S_RS0101120 C5S_RS0101120 C5S_RS0101120 238814 240013 - cell division protein FtsW gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101120 C5S_RS0101125 C5S_RS0101125 murD murD 240010 241332 - UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101125 C5S_RS0101130 C5S_RS0101130 mraY mraY 241332 242405 - phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101130 C5S_RS0101135 C5S_RS0101135 C5S_RS0101135 242389 243765 - UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101135 C5S_RS0101140 C5S_RS0101140 murE murE 243762 245258 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101140 C5S_RS0101145 C5S_RS0101145 C5S_RS0101145 245259 246998 - cell division protein FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101145 C5S_RS0101155 C5S_RS0101155 C5S_RS0101155 247318 248256 - ribosomal RNA small subunit methyltransferase H gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101155 C5S_RS0101160 C5S_RS0101160 ilvH ilvH 248378 248854 - acetolactate synthase small subunit with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101160 C5S_RS0101165 C5S_RS0101165 C5S_RS0101165 248859 250574 - acetolactate synthase large subunit catalyzes the formation of 2-acetolactate from pyruvate%2C leucine sensitive gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101165 C5S_RS0101175 C5S_RS0101175 C5S_RS0101175 252192 253628 + serine endoprotease protease Do%3B required at high temperature%3B degrades damaged proteins gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101175 C5S_RS0101180 C5S_RS0101180 dapD dapD 253672 254496 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101180 C5S_RS0101185 C5S_RS0101185 C5S_RS0101185 254557 255351 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101185 C5S_RS0101190 C5S_RS0101190 C5S_RS0101190 255614 256348 + 30S ribosomal protein S2 gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101190 C5S_RS0101195 C5S_RS0101195 tsf tsf 256425 257231 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101195 C5S_RS0101200 C5S_RS0101200 C5S_RS0101200 257282 258010 + uridylate kinase gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101200 C5S_RS0101205 C5S_RS0101205 frr frr 258090 258647 + ribosome-recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101205 C5S_RS0101210 C5S_RS0101210 C5S_RS0101210 258730 259926 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101210 C5S_RS0101215 C5S_RS0101215 C5S_RS0101215 260019 260774 + UDP pyrophosphate synthase gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101215 C5S_RS0101220 C5S_RS0101220 C5S_RS0101220 261008 263410 + hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101220 C5S_RS0101225 C5S_RS0101225 C5S_RS0101225 263537 263992 + 3-hydroxyacyl-ACP dehydratase gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101225 C5S_RS0101230 C5S_RS0101230 dnaE dnaE 264029 267514 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101230 C5S_RS0101235 C5S_RS0101235 C5S_RS0101235 267642 269360 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101235 C5S_RS0101240 C5S_RS0101240 flhB flhB 269701 270852 + flagellar biosynthetic protein FlhB membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101240 C5S_RS0101245 C5S_RS0101245 C5S_RS0101245 270845 272935 + flagellar biosynthesis protein FlhA gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101245 C5S_RS0101250 C5S_RS0101250 C5S_RS0101250 273059 274783 - arginine--tRNA ligase gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101250 C5S_RS0101260 C5S_RS0101260 C5S_RS0101260 275207 276756 + 16S ribosomal RNA rRNA gene247 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101260 C5S_RS0101265 C5S_RS0101265 C5S_RS0101265 276812 276888 + tRNA-Ile tRNA gene248 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101265 C5S_RS0101270 C5S_RS0101270 C5S_RS0101270 276903 276975 + tRNA-Ala tRNA gene249 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101270 C5S_RS0101280 C5S_RS0101280 C5S_RS0101280 277763 277981 - ribonuclease H gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101280 C5S_RS0101285 C5S_RS0101285 C5S_RS0101285 277939 278232 - ribonuclease H gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101285 C5S_RS0101290 C5S_RS0101290 C5S_RS0101290 278285 278998 + DNA polymerase III subunit epsilon gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101290 C5S_RS0101295 C5S_RS0101295 C5S_RS0101295 279070 279143 + tRNA-Asp tRNA gene253 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101295 C5S_RS0101300 C5S_RS0101300 C5S_RS0101300 279223 279804 + phosphoheptose isomerase gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101300 C5S_RS0101305 C5S_RS0101305 C5S_RS0101305 279911 280387 + xanthine phosphoribosyltransferase gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101305 C5S_RS0101310 C5S_RS0101310 C5S_RS0101310 280489 281073 + protein GrpE 1 gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101310 C5S_RS0101315 C5S_RS0101315 C5S_RS0101315 281152 281451 - protein RnfH gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101315 C5S_RS0101320 C5S_RS0101320 C5S_RS0101320 281545 282033 + SsrA-binding protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101320 C5S_RS0101325 C5S_RS0101325 C5S_RS0101325 282042 282527 + tRNA-specific adenosine deaminase gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101325 C5S_RS0101330 C5S_RS0101330 acpS acpS 282528 282908 - holo-ACP synthase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101330 C5S_RS0101335 C5S_RS0101335 C5S_RS0101335 283034 283885 - GTPase Era gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101335 C5S_RS0101340 C5S_RS0101340 rnc rnc 283882 284562 - ribonuclease 3 cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101340 C5S_RS0101345 C5S_RS0101345 C5S_RS0101345 284693 285637 - signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101345 C5S_RS0101350 C5S_RS0101350 C5S_RS0101350 285653 287485 - elongation factor 4 gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101350 C5S_RS0101355 C5S_RS0101355 mnmA mnmA 287609 288787 + tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101355 C5S_RS0101360 C5S_RS0101360 C5S_RS0101360 288823 289458 + High frequency lysogenization protein HflD homolog gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101360 C5S_RS0101365 C5S_RS0101365 C5S_RS0101365 289497 290867 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101365 C5S_RS0101370 C5S_RS0101370 C5S_RS0101370 290891 291556 + murein transglycosylase gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101370 C5S_RS0101375 C5S_RS0101375 C5S_RS0101375 291670 292452 + enoyl-ACP reductase gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101375 C5S_RS0101380 C5S_RS0101380 C5S_RS0101380 292639 294588 + exoribonuclease 2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101380 C5S_RS0101385 C5S_RS0101385 C5S_RS0101385 294696 295343 + membrane protein gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101385 C5S_RS0101390 C5S_RS0101390 C5S_RS0101390 295381 296016 + octanoyltransferase gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101390 C5S_RS0101395 C5S_RS0101395 C5S_RS0101395 296136 297107 + lipoyl synthase gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101395 C5S_RS0101400 C5S_RS0101400 C5S_RS0101400 297212 297922 + orotidine 5'-phosphate decarboxylase gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101400 C5S_RS0101410 C5S_RS0101410 ribA ribA 297970 298554 + GTP cyclohydrolase-2 catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101410 C5S_RS0101415 C5S_RS0101415 C5S_RS0101415 298658 299065 - DNA-binding protein H-NS homolog gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101415 C5S_RS0101420 C5S_RS0101420 cls cls 299411 300871 - cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101420 C5S_RS0101425 C5S_RS0101425 C5S_RS0101425 301252 301659 - acyl-CoA esterase gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101425 C5S_RS0101430 C5S_RS0101430 C5S_RS0101430 301696 302229 - intracellular septation protein A gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101430 C5S_RS0101435 C5S_RS0101435 C5S_RS0101435 302257 303000 - hypothetical protein gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101435 C5S_RS0101440 C5S_RS0101440 C5S_RS0101440 303105 303914 - tryptophan synthase subunit alpha gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101440 C5S_RS0101445 C5S_RS0101445 C5S_RS0101445 303889 305100 - tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101445 C5S_RS0101450 C5S_RS0101450 C5S_RS0101450 305138 306499 - phosphoribosylanthranilate isomerase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101450 C5S_RS0101455 C5S_RS0101455 C5S_RS0101455 306480 307508 - anthranilate phosphoribosyltransferase gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101455 C5S_RS0101460 C5S_RS0101460 C5S_RS0101460 307743 308666 + drug/metabolite transporter DMT permease gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101460 C5S_RS0101465 C5S_RS0101465 C5S_RS0101465 308695 309447 + ribosomal large subunit pseudouridine synthase B catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101465 C5S_RS0101470 C5S_RS0101470 C5S_RS0101470 309522 310532 + protease multicopy suppressor of htrA(degP) gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101470 C5S_RS0101475 C5S_RS0101475 C5S_RS0101475 310618 313203 + DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101475 C5S_RS0101480 C5S_RS0101480 C5S_RS0101480 313255 314055 - inositol-1-monophosphatase gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101480 C5S_RS0101485 C5S_RS0101485 C5S_RS0101485 314302 315393 + 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101485 C5S_RS0101490 C5S_RS0101490 C5S_RS0101490 315444 316550 + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101490 C5S_RS0101495 C5S_RS0101495 hisS hisS 316576 317847 + histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101495 C5S_RS0101500 C5S_RS0101500 C5S_RS0101500 317907 319160 + serine hydroxymethyltransferase gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101500 C5S_RS0101505 C5S_RS0101505 bioD bioD 319248 319922 - ATP-dependent dethiobiotin synthetase BioD DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101505 C5S_RS0101510 C5S_RS0101510 C5S_RS0101510 320286 321317 - biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101510 C5S_RS0101515 C5S_RS0101515 C5S_RS0101515 321396 322682 + adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101515 C5S_RS0101520 C5S_RS0101520 C5S_RS0101520 322691 323695 - 6-phosphogluconolactonase gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101520 C5S_RS0101525 C5S_RS0101525 C5S_RS0101525 323819 326257 - transcription-repair-coupling factor gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101525 C5S_RS0101530 C5S_RS0101530 C5S_RS0101530 326730 327929 + lipoprotein-releasing system protein LolC gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101530 C5S_RS0101535 C5S_RS0101535 lolD lolD 327922 328608 + lipoprotein-releasing system ATP-binding protein LolD outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101535 C5S_RS0101545 C5S_RS0101545 C5S_RS0101545 329945 330943 + glyceraldehyde-3-phosphate dehydrogenase gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101545 C5S_RS0101550 C5S_RS0101550 C5S_RS0101550 331271 331786 - flavodoxin gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101550 C5S_RS0101555 C5S_RS0101555 C5S_RS0101555 331993 333444 + deoxyribodipyrimidine photolyase gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101555 C5S_RS0101560 C5S_RS0101560 C5S_RS0101560 333441 334184 + Nif3-like dinuclear metal center hexameric protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101560 C5S_RS0101565 C5S_RS0101565 C5S_RS0101565 334309 337038 + 2-oxoglutarate dehydrogenase E1 gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101565 C5S_RS0101570 C5S_RS0101570 C5S_RS0101570 337054 338316 + dienelactone hydrolase component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101570 C5S_RS0101575 C5S_RS0101575 gpmA gpmA 338414 339109 + 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101575 C5S_RS0101580 C5S_RS0101580 C5S_RS0101580 339293 340255 + ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101580 C5S_RS0101585 C5S_RS0101585 C5S_RS0101585 340321 341112 + glycerol transporter gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101585 C5S_RS0101590 C5S_RS0101590 C5S_RS0101590 341121 341888 - triosephosphate isomerase gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101590 C5S_RS0101595 C5S_RS0101595 ihfB ihfB 341987 342271 - integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101595 C5S_RS0101600 C5S_RS0101600 rpsA rpsA 342367 344043 - 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101600 C5S_RS0101605 C5S_RS0101605 C5S_RS0101605 344171 344485 - cytidylate kinase gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101605 C5S_RS0101610 C5S_RS0101610 C5S_RS0101610 344572 344826 - cytidylate kinase gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101610 C5S_RS0101615 C5S_RS0101615 C5S_RS0101615 344882 346165 - 3-phosphoshikimate 1-carboxyvinyltransferase gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101615 C5S_RS0101620 C5S_RS0101620 C5S_RS0101620 346233 347318 - phosphoserine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101620 C5S_RS0101625 C5S_RS0101625 C5S_RS0101625 347357 348640 - serine--tRNA ligase gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101625 C5S_RS0101630 C5S_RS0101630 C5S_RS0101630 348989 349948 + thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101630 C5S_RS0101635 C5S_RS0101635 C5S_RS0101635 350055 350273 + translation initiation factor IF-1 gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101635 C5S_RS0101640 C5S_RS0101640 C5S_RS0101640 350443 352203 + aspartate--tRNA ligase gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101640 C5S_RS0101645 C5S_RS0101645 znuB znuB 352214 353002 - zinc transporter involved in transport of zinc(II) with ZnuA and C gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101645 C5S_RS0101650 C5S_RS0101650 znuC znuC 353060 353776 - Mn2+/Zn2+ABC transporter ATP-binding protein involved in transport of zinc(II) with ZnuA and C gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101650 C5S_RS0101655 C5S_RS0101655 C5S_RS0101655 355094 356536 - pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101655 C5S_RS0101660 C5S_RS0101660 C5S_RS0101660 356820 358295 + glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101660 C5S_RS0101665 C5S_RS0101665 C5S_RS0101665 358480 359358 + protease HtpX metalloprotease gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101665 C5S_RS0101670 C5S_RS0101670 C5S_RS0101670 359707 359916 + cold-shock protein CspC gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101670 C5S_RS0101680 C5S_RS0101680 C5S_RS0101680 360219 361784 + membrane protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101680 C5S_RS0101685 C5S_RS0101685 C5S_RS0101685 361814 362479 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101685 C5S_RS0101690 C5S_RS0101690 minE minE 362625 362876 - cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101690 C5S_RS0101695 C5S_RS0101695 C5S_RS0101695 362880 363692 - septum site-determining protein MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101695 C5S_RS0101700 C5S_RS0101700 minC minC 363719 364432 - septum site-determining protein MinC blocks the formation of polar Z-ring septums gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101700 C5S_RS0101710 C5S_RS0101710 C5S_RS0101710 364833 365675 + 16S rRNA methyltransferase gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101710 C5S_RS0101715 C5S_RS0101715 C5S_RS0101715 365697 365780 - tRNA-Leu tRNA gene334 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101715 C5S_RS0101720 C5S_RS0101720 C5S_RS0101720 366037 366121 + tRNA-Ser tRNA gene335 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101720 C5S_RS0101725 C5S_RS0101725 C5S_RS0101725 366227 367276 - OmpA-like protein gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101725 C5S_RS0101730 C5S_RS0101730 C5S_RS0101730 367432 368967 - membrane protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101730 C5S_RS0101735 C5S_RS0101735 C5S_RS0101735 369241 370293 + dihydroorotase gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101735 C5S_RS0101740 C5S_RS0101740 C5S_RS0101740 370313 370741 - flagellar biosynthesis protein FlgN gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101740 C5S_RS0101745 C5S_RS0101745 C5S_RS0101745 370793 371473 - flagella basal body P-ring formation protein FlgA gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101745 C5S_RS0101755 C5S_RS0101755 C5S_RS0101755 371756 372157 + flagellar biosynthesis protein FlgB gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101755 C5S_RS0101760 C5S_RS0101760 flgC flgC 372166 372576 + flagellar basal-body rod protein FlgC with FlgF and B makes up the proximal portion of the flagellar basal body rod gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101760 C5S_RS0101765 C5S_RS0101765 C5S_RS0101765 372588 373298 + flagellar basal body rod modification protein FlgD gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101765 C5S_RS0101770 C5S_RS0101770 C5S_RS0101770 373339 374565 + flagellar hook protein FlgE gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101770 C5S_RS0101775 C5S_RS0101775 flgF flgF 374592 375350 + flagellar basal body rod protein FlgF FlgF%2C with FlgB and C%2C makes up the proximal portion of the flagellar basal body rod gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101775 C5S_RS0101780 C5S_RS0101780 flgG flgG 375368 376150 + flagellar basal body rod protein FlgG makes up the distal portion of the flagellar basal body rod gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101780 C5S_RS0101785 C5S_RS0101785 flgH flgH 376234 376950 + flagellar L-ring protein part of the flagellar basal body which consists of four rings L%2CP%2C S and M mounted on a central rod gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101785 C5S_RS0101790 C5S_RS0101790 flgI flgI 377131 378288 + flagellar basal body P-ring protein part of the basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod%3B Vibrio parahaemolyticus%2C Yersinia%2C Bradyrhizobium and other bacteria have two copies of this and other flagellar genes%3B the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101790 C5S_RS0101795 C5S_RS0101795 C5S_RS0101795 378288 378587 + flagellar protein FlgJ gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101795 C5S_RS0101800 C5S_RS0101800 C5S_RS0101800 378688 380319 + flagellar hook-associated protein 1 gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101800 C5S_RS0101805 C5S_RS0101805 C5S_RS0101805 380484 383192 - ribonuclease E gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101805 C5S_RS0101810 C5S_RS0101810 C5S_RS0101810 383527 384471 + ribosomal large subunit pseudouridine synthase C gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101810 C5S_RS0101815 C5S_RS0101815 C5S_RS0101815 384517 384681 + 50S ribosomal protein L32 gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101815 C5S_RS0101820 C5S_RS0101820 C5S_RS0101820 385103 385582 + malonyl CoA-ACP transacylase gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101820 C5S_RS0101825 C5S_RS0101825 C5S_RS0101825 385609 386061 + malonyl CoA-ACP transacylase gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101825 C5S_RS0101830 C5S_RS0101830 C5S_RS0101830 386048 386782 + 3-oxoacyl-ACP reductase gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101830 C5S_RS0101835 C5S_RS0101835 C5S_RS0101835 386859 387101 + acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101835 C5S_RS0101840 C5S_RS0101840 C5S_RS0101840 387172 387810 + thymidylate kinase gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101840 C5S_RS0101845 C5S_RS0101845 C5S_RS0101845 387807 388787 + DNA polymerase III subunit delta' gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101845 C5S_RS0101850 C5S_RS0101850 C5S_RS0101850 388821 389615 + DNAse gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101850 C5S_RS0101855 C5S_RS0101855 C5S_RS0101855 389711 391144 + PTS glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101855 C5S_RS0101860 C5S_RS0101860 C5S_RS0101860 391164 391508 + purine nucleoside phosphoramidase gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101860 C5S_RS0101865 C5S_RS0101865 C5S_RS0101865 391585 392094 + hypothetical protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101865 C5S_RS0101870 C5S_RS0101870 C5S_RS0101870 392343 393491 - Porin-like protein BU359 gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101870 C5S_RS0101875 C5S_RS0101875 C5S_RS0101875 393631 395031 - asparaginyl-tRNA synthetase gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101875 C5S_RS0101880 C5S_RS0101880 C5S_RS0101880 395179 396378 - nicotinate phosphoribosyltransferase catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101880 C5S_RS0101885 C5S_RS0101885 C5S_RS0101885 396651 396809 + dihydroorotate dehydrogenase gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101885 C5S_RS0101890 C5S_RS0101890 C5S_RS0101890 396800 397663 + dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101890 C5S_RS0101895 C5S_RS0101895 rlmL rlmL 397839 399944 + ribosomal RNA large subunit methyltransferase K/L catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101895 C5S_RS0101900 C5S_RS0101900 C5S_RS0101900 399964 401754 + ABC transporter ATP-binding protein Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101900 C5S_RS0101905 C5S_RS0101905 C5S_RS0101905 401758 402732 - sulfurtransferase gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101905 C5S_RS0101910 C5S_RS0101910 C5S_RS0101910 402789 405656 - valine--tRNA ligase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101910 C5S_RS0101915 C5S_RS0101915 C5S_RS0101915 405733 407232 - cytosol aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101915 C5S_RS0101925 C5S_RS0101925 C5S_RS0101925 407492 408508 + ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101925 C5S_RS0101930 C5S_RS0101930 C5S_RS0101930 408627 409559 + aspartate carbamoyltransferase gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101930 C5S_RS0101935 C5S_RS0101935 C5S_RS0101935 409567 410031 + aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101935 C5S_RS0101940 C5S_RS0101940 C5S_RS0101940 410077 410463 + RutC family protein BU371 gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101940 C5S_RS0101945 C5S_RS0101945 C5S_RS0101945 410550 412355 - DEAD/DEAH box family ATP-dependent RNA helicase gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101945 C5S_RS0101950 C5S_RS0101950 C5S_RS0101950 412736 414859 - polyribonucleotide nucleotidyltransferase gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101950 C5S_RS0101955 C5S_RS0101955 C5S_RS0101955 415061 415330 - 30S ribosomal protein S15 gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101955 C5S_RS0101960 C5S_RS0101960 C5S_RS0101960 415435 416373 - tRNA pseudouridine synthase B gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101960 C5S_RS0101965 C5S_RS0101965 C5S_RS0101965 416411 416773 - ribosome-binding factor A gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101965 C5S_RS0101970 C5S_RS0101970 infB infB 416819 419413 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101970 C5S_RS0101975 C5S_RS0101975 nusA nusA 419431 420921 - transcription termination/antitermination protein NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101975 C5S_RS0101980 C5S_RS0101980 C5S_RS0101980 421263 421348 - tRNA-Leu tRNA gene385 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101980 C5S_RS0101985 C5S_RS0101985 C5S_RS0101985 421394 421723 - protein-export membrane protein SecG gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101985 C5S_RS0101990 C5S_RS0101990 glmM glmM 421986 423320 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101990 C5S_RS0101995 C5S_RS0101995 hflB hflB 423540 425375 - ATP-dependent metalloprotease inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0101995 C5S_RS0102005 C5S_RS0102005 greA greA 426134 426613 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102005 C5S_RS0102010 C5S_RS0102010 C5S_RS0102010 427137 427379 + hypothetical protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102010 C5S_RS0102015 C5S_RS0102015 C5S_RS0102015 427441 428691 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102015 C5S_RS0102020 C5S_RS0102020 rplU rplU 428830 429156 + 50S ribosomal protein L21 gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102020 C5S_RS0102025 C5S_RS0102025 rpmA rpmA 429161 429415 + 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102025 C5S_RS0102030 C5S_RS0102030 C5S_RS0102030 429567 430571 + GTPase Obg gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102030 C5S_RS0102035 C5S_RS0102035 C5S_RS0102035 430639 431031 - 30S ribosomal protein S9 gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102035 C5S_RS0102040 C5S_RS0102040 C5S_RS0102040 431052 431480 - 50S ribosomal protein L13 gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102040 C5S_RS0102045 C5S_RS0102045 C5S_RS0102045 431732 432889 + bifunctional chorismate mutase/prephenate dehydratase gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102045 C5S_RS0102050 C5S_RS0102050 C5S_RS0102050 433071 434426 + signal recognition particle protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102050 C5S_RS0102055 C5S_RS0102055 C5S_RS0102055 434535 434774 + 30S ribosomal protein S16 gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102055 C5S_RS0102060 C5S_RS0102060 C5S_RS0102060 434776 435306 + ribosome maturation factor RimM gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102060 C5S_RS0102065 C5S_RS0102065 trmD trmD 435321 436034 + tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102065 C5S_RS0102070 C5S_RS0102070 C5S_RS0102070 436133 436480 + 50S ribosomal protein L19 gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102070 C5S_RS0102075 C5S_RS0102075 tldD tldD 436564 438015 - protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102075 C5S_RS0102085 C5S_RS0102085 C5S_RS0102085 438173 438625 + 3-dehydroquinate dehydratase gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102085 C5S_RS0102090 C5S_RS0102090 C5S_RS0102090 438817 439113 - Fis family transcriptional regulator gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102090 C5S_RS0102095 C5S_RS0102095 rluD rluD 439282 440223 - 23S rRNA pseudouridylate synthase responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102095 C5S_RS0102100 C5S_RS0102100 C5S_RS0102100 440385 441125 + outer membrane protein assembly factor BamD gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102100 C5S_RS0102105 C5S_RS0102105 C5S_RS0102105 441291 443927 + alanyl-tRNA synthetase gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102105 C5S_RS0102110 C5S_RS0102110 C5S_RS0102110 444122 444295 + carbon storage regulator homolog affects carbohydrate metabolism%3B has regulatory role in many processes gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102110 C5S_RS0102115 C5S_RS0102115 C5S_RS0102115 444454 444545 + tRNA-Ser tRNA gene411 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102115 C5S_RS0102120 C5S_RS0102120 C5S_RS0102120 444563 444636 + tRNA-Arg tRNA gene412 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102120 C5S_RS0102125 C5S_RS0102125 C5S_RS0102125 444753 446309 + glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102125 C5S_RS0102130 C5S_RS0102130 C5S_RS0102130 446456 447592 - S-adenosylmethionine synthase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102130 C5S_RS0102135 C5S_RS0102135 C5S_RS0102135 447827 448579 + endonuclease-1 gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102135 C5S_RS0102140 C5S_RS0102140 C5S_RS0102140 448551 449312 + ribosomal RNA small subunit methyltransferase E gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102140 C5S_RS0102145 C5S_RS0102145 C5S_RS0102145 449386 450057 - ribose-5-phosphate isomerase A gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102145 C5S_RS0102150 C5S_RS0102150 C5S_RS0102150 450244 450318 - tRNA-Gln tRNA gene418 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102150 C5S_RS0102155 C5S_RS0102155 C5S_RS0102155 450412 450493 - tRNA-Leu tRNA gene419 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102155 C5S_RS0102160 C5S_RS0102160 C5S_RS0102160 450505 450581 - tRNA-Met tRNA gene420 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102160 C5S_RS0102165 C5S_RS0102165 C5S_RS0102165 450684 452399 + glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102165 C5S_RS0102170 C5S_RS0102170 pyrG pyrG 452573 454210 + CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102170 C5S_RS0102175 C5S_RS0102175 eno eno 454240 455544 + enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102175 C5S_RS0102180 C5S_RS0102180 C5S_RS0102180 455700 456704 - protein NlpD/LppB gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102180 C5S_RS0102185 C5S_RS0102185 C5S_RS0102185 456794 457279 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102185 C5S_RS0102190 C5S_RS0102190 C5S_RS0102190 457295 458008 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102190 C5S_RS0102195 C5S_RS0102195 C5S_RS0102195 458091 458306 - cell division protein FtsB gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102195 C5S_RS0102200 C5S_RS0102200 C5S_RS0102200 458364 458984 - adenylyl-sulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102200 C5S_RS0102205 C5S_RS0102205 cysN cysN 458985 460406 - sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102205 C5S_RS0102210 C5S_RS0102210 C5S_RS0102210 460425 461333 - sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102210 C5S_RS0102215 C5S_RS0102215 C5S_RS0102215 461343 462764 - siroheme synthase gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102215 C5S_RS0102220 C5S_RS0102220 C5S_RS0102220 463103 463837 - phosphoadenosine phosphosulfate reductase gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102220 C5S_RS0102225 C5S_RS0102225 C5S_RS0102225 463853 465562 - sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102225 C5S_RS0102230 C5S_RS0102230 cysJ cysJ 465562 467367 - sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102230 C5S_RS0102235 C5S_RS0102235 C5S_RS0102235 467558 469966 - DNA mismatch repair protein MutS gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102235 C5S_RS0102240 C5S_RS0102240 C5S_RS0102240 470123 470761 + thiol:disulfide interchange protein DsbA gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102240 C5S_RS0102245 C5S_RS0102245 C5S_RS0102245 470882 471742 + 5'-3' exonuclease gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102245 C5S_RS0102250 C5S_RS0102250 C5S_RS0102250 471805 472422 - GTP-binding protein gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102250 C5S_RS0102255 C5S_RS0102255 C5S_RS0102255 472673 474496 + GTP-binding protein gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102255 C5S_RS0102260 C5S_RS0102260 C5S_RS0102260 474619 475242 - guanylate kinase gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102260 C5S_RS0102265 C5S_RS0102265 C5S_RS0102265 475342 476301 - tRNA-modifying protein YgfZ gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102265 C5S_RS0102270 C5S_RS0102270 C5S_RS0102270 476541 477569 + peptide chain release factor 2 gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102270 C5S_RS0102275 C5S_RS0102275 lysS lysS 477579 479099 + lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102275 C5S_RS0102280 C5S_RS0102280 C5S_RS0102280 479165 480412 + diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102280 C5S_RS0102285 C5S_RS0102285 C5S_RS0102285 480478 481323 + prolipoprotein diacylglyceryl transferase transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102285 C5S_RS0102290 C5S_RS0102290 C5S_RS0102290 481337 482131 + thymidylate synthase gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102290 C5S_RS0102295 C5S_RS0102295 C5S_RS0102295 482199 483518 + dimethylallyladenosine tRNA methylthiotransferase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102295 C5S_RS0102305 C5S_RS0102305 C5S_RS0102305 484088 484963 + magnesium and cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102305 C5S_RS0102310 C5S_RS0102310 leuS leuS 485067 487646 + leucyl-tRNA synthetase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102310 C5S_RS0102315 C5S_RS0102315 C5S_RS0102315 487686 488681 + DNA polymerase III subunit delta gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102315 C5S_RS0102320 C5S_RS0102320 C5S_RS0102320 488704 489348 + nicotinate-nucleotide adenylyltransferase gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102320 C5S_RS0102325 C5S_RS0102325 C5S_RS0102325 489409 489639 + sulfurtransferase TusA gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102325 C5S_RS0102330 C5S_RS0102330 C5S_RS0102330 489786 490898 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102330 C5S_RS0102335 C5S_RS0102335 C5S_RS0102335 491197 491787 + membrane protein gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102335 C5S_RS0102340 C5S_RS0102340 C5S_RS0102340 491900 493072 + phosphoglycerate kinase gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102340 C5S_RS0102345 C5S_RS0102345 C5S_RS0102345 493121 494164 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102345 C5S_RS0102350 C5S_RS0102350 C5S_RS0102350 494300 495145 + mechanosensitive ion channel protein MscS participates in the regulation of osmotic pressure changes within the cel gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102350 C5S_RS0102360 C5S_RS0102360 C5S_RS0102360 498432 501956 + exodeoxyribonuclease V subunit beta gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102360 C5S_RS0102365 C5S_RS0102365 C5S_RS0102365 501962 503770 + RecBCD enzyme subunit RecD gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102365 C5S_RS0102370 C5S_RS0102370 C5S_RS0102370 503809 505137 - amino-acid acetyltransferase catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102370 C5S_RS0102375 C5S_RS0102375 C5S_RS0102375 505319 505395 - tRNA-Met tRNA gene463 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102375 C5S_RS0102380 C5S_RS0102380 C5S_RS0102380 505504 506583 + murein transglycosylase gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102380 C5S_RS0102385 C5S_RS0102385 ribH ribH 506622 507104 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102385 C5S_RS0102390 C5S_RS0102390 C5S_RS0102390 507134 508105 + thiamine-monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102390 C5S_RS0102395 C5S_RS0102395 C5S_RS0102395 508143 508586 + diaminohydroxyphosphoribosylamino-pyrimidine deaminase gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102395 C5S_RS0102400 C5S_RS0102400 C5S_RS0102400 508629 509252 + 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102400 C5S_RS0102405 C5S_RS0102405 C5S_RS0102405 509289 509720 + N utilization substance protein B homolog gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102405 C5S_RS0102410 C5S_RS0102410 C5S_RS0102410 509775 511601 - 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102410 C5S_RS0102415 C5S_RS0102415 C5S_RS0102415 511659 512507 - farnesyl-diphosphate synthase gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102415 C5S_RS0102420 C5S_RS0102420 C5S_RS0102420 512559 513731 - MFS transporter gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102420 C5S_RS0102425 C5S_RS0102425 C5S_RS0102425 513805 514149 + sulfurtransferase TusE gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102425 C5S_RS0102430 C5S_RS0102430 C5S_RS0102430 514170 515027 - protoheme IX farnesyltransferase gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102430 C5S_RS0102435 C5S_RS0102435 C5S_RS0102435 515055 515372 - cytochrome bo(3) ubiquinol oxidase subunit 4 gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102435 C5S_RS0102440 C5S_RS0102440 C5S_RS0102440 515372 515989 - cytochrome bo(3) ubiquinol oxidase subunit 3 gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102440 C5S_RS0102445 C5S_RS0102445 C5S_RS0102445 515986 517974 - cytochrome O ubiquinol oxidase gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102445 C5S_RS0102450 C5S_RS0102450 C5S_RS0102450 517979 518896 - cytochrome O ubiquinol oxidase gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102450 C5S_RS0102455 C5S_RS0102455 C5S_RS0102455 519168 519482 + BolA family transcriptional regulator gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102455 C5S_RS0102460 C5S_RS0102460 C5S_RS0102460 519617 520945 + trigger factor gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102460 C5S_RS0102465 C5S_RS0102465 C5S_RS0102465 521080 521706 + Clp protease proteolytic subunit ClpP gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102465 C5S_RS0102470 C5S_RS0102470 C5S_RS0102470 521805 523094 + ATP-dependent Clp protease ATP-binding subunit ClpX gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102470 C5S_RS0102475 C5S_RS0102475 C5S_RS0102475 523286 525619 + peptidase gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102475 C5S_RS0102480 C5S_RS0102480 C5S_RS0102480 525761 527632 + peptidylprolyl isomerase gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102480 C5S_RS0102490 C5S_RS0102490 C5S_RS0102490 528599 530368 + multidrug ABC transporter ATP-binding protein gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102490 C5S_RS0102495 C5S_RS0102495 C5S_RS0102495 530370 532112 + multidrug resistance-like ATP-binding protein MdlB gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102495 C5S_RS0102500 C5S_RS0102500 C5S_RS0102500 532407 533492 + DNA polymerase III subunit gamma gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102500 C5S_RS0102505 C5S_RS0102505 C5S_RS0102505 533812 534141 + hypothetical protein gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102505 C5S_RS0102510 C5S_RS0102510 C5S_RS0102510 534287 536161 + chaperone protein HtpG molecular chaperone gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102510 C5S_RS0102515 C5S_RS0102515 adk adk 536234 536881 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102515 C5S_RS0102520 C5S_RS0102520 C5S_RS0102520 536886 536959 - tRNA-Arg tRNA gene491 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102520 C5S_RS0102525 C5S_RS0102525 C5S_RS0102525 537112 537969 + bifunctional protein FolD gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102525 C5S_RS0102530 C5S_RS0102530 cysS cysS 537966 539360 - cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102530 C5S_RS0102535 C5S_RS0102535 C5S_RS0102535 539621 539884 + hypothetical protein gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102535 C5S_RS0102540 C5S_RS0102540 C5S_RS0102540 539991 540200 - cold-shock protein CspE gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102540 C5S_RS0102550 C5S_RS0102550 C5S_RS0102550 540489 540604 - 5S ribosomal RNA rRNA gene496 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102550 C5S_RS0102555 C5S_RS0102555 C5S_RS0102555 540697 543634 - 23S ribosomal RNA rRNA gene497 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102555 C5S_RS0102560 C5S_RS0102560 C5S_RS0102560 543791 543863 - tRNA-Glu tRNA gene498 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102560 C5S_RS0102570 C5S_RS0102570 C5S_RS0102570 544014 544835 - shikimate dehydrogenase (NADP+) gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102570 C5S_RS0102575 C5S_RS0102575 C5S_RS0102575 544828 545400 - tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102575 C5S_RS0102580 C5S_RS0102580 C5S_RS0102580 545453 545926 - protein Smg gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102580 C5S_RS0102585 C5S_RS0102585 C5S_RS0102585 546170 546691 + peptide deformylase gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102585 C5S_RS0102590 C5S_RS0102590 fmt fmt 546699 547643 + methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102590 C5S_RS0102595 C5S_RS0102595 C5S_RS0102595 547771 548163 - 50S ribosomal protein L17 gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102595 C5S_RS0102600 C5S_RS0102600 C5S_RS0102600 548208 549197 - DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102600 C5S_RS0102605 C5S_RS0102605 C5S_RS0102605 549226 549846 - 30S ribosomal protein S4 gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102605 C5S_RS0102610 C5S_RS0102610 C5S_RS0102610 549872 550267 - 30S ribosomal protein S11 gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102610 C5S_RS0102615 C5S_RS0102615 C5S_RS0102615 550285 550641 - 30S ribosomal protein S13 gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102615 C5S_RS0102620 C5S_RS0102620 C5S_RS0102620 550735 550851 - 50S ribosomal protein L36 gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102620 C5S_RS0102625 C5S_RS0102625 secY secY 550877 552190 - protein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102625 C5S_RS0102630 C5S_RS0102630 C5S_RS0102630 552201 552635 - 50S ribosomal protein L15 gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102630 C5S_RS0102635 C5S_RS0102635 rpmD rpmD 552640 552819 - 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102635 C5S_RS0102640 C5S_RS0102640 C5S_RS0102640 552829 553332 - 30S ribosomal protein S5 gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102640 C5S_RS0102645 C5S_RS0102645 C5S_RS0102645 553348 553716 - 50S ribosomal protein L18 gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102645 C5S_RS0102650 C5S_RS0102650 C5S_RS0102650 553718 554254 - 50S ribosomal protein L6 gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102650 C5S_RS0102655 C5S_RS0102655 C5S_RS0102655 554265 554657 - 30S ribosomal protein S8 gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102655 C5S_RS0102660 C5S_RS0102660 rpsN rpsN 554686 554991 - 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102660 C5S_RS0102665 C5S_RS0102665 C5S_RS0102665 555009 555548 - 50S ribosomal protein L5 gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102665 C5S_RS0102670 C5S_RS0102670 rplX rplX 555563 555877 - 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102670 C5S_RS0102675 C5S_RS0102675 C5S_RS0102675 555903 556271 - 50S ribosomal protein L14 gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102675 C5S_RS0102680 C5S_RS0102680 C5S_RS0102680 556385 556639 - 30S ribosomal protein S17 gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102680 C5S_RS0102685 C5S_RS0102685 C5S_RS0102685 556636 556833 - 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102685 C5S_RS0102690 C5S_RS0102690 C5S_RS0102690 556833 557243 - 50S ribosomal protein L16 gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102690 C5S_RS0102695 C5S_RS0102695 C5S_RS0102695 557264 557965 - 30S ribosomal protein S3 gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102695 C5S_RS0102700 C5S_RS0102700 C5S_RS0102700 557984 558316 - 50S ribosomal protein L22 gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102700 C5S_RS0102705 C5S_RS0102705 C5S_RS0102705 558352 558630 - 30S ribosomal protein S19 gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102705 C5S_RS0102710 C5S_RS0102710 C5S_RS0102710 558650 559471 - 50S ribosomal protein L2 gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102710 C5S_RS0102715 C5S_RS0102715 C5S_RS0102715 559486 559788 - 50S ribosomal protein L23 gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102715 C5S_RS0102720 C5S_RS0102720 rplD rplD 559785 560390 - 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102720 C5S_RS0102725 C5S_RS0102725 C5S_RS0102725 560408 561037 - 50S ribosomal protein L3 gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102725 C5S_RS0102730 C5S_RS0102730 rpsJ rpsJ 561068 561379 - 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102730 C5S_RS0102735 C5S_RS0102735 tuf tuf 561710 562894 - elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102735 C5S_RS0102740 C5S_RS0102740 fusA fusA 562962 565070 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102740 C5S_RS0102745 C5S_RS0102745 C5S_RS0102745 565185 565655 - 30S ribosomal protein S7 gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102745 C5S_RS0102750 C5S_RS0102750 C5S_RS0102750 565697 566071 - 30S ribosomal protein S12 gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102750 C5S_RS0102755 C5S_RS0102755 C5S_RS0102755 566205 566492 - protein TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102755 C5S_RS0102760 C5S_RS0102760 C5S_RS0102760 566504 566863 - protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur transfer that results in thiouridation to U34 position in some tRNAs gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102760 C5S_RS0102765 C5S_RS0102765 C5S_RS0102765 566882 567268 - sulfurtransferase TusD gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102765 C5S_RS0102770 C5S_RS0102770 C5S_RS0102770 567351 568115 - peptidylprolyl isomerase gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102770 C5S_RS0102775 C5S_RS0102775 C5S_RS0102775 568538 569764 - acetylornithine aminotransferase gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102775 C5S_RS0102780 C5S_RS0102780 C5S_RS0102780 570081 571247 + protein TsgA gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102780 C5S_RS0102785 C5S_RS0102785 C5S_RS0102785 571309 572316 - tryptophan--tRNA ligase catalyzes a two-step reaction%2C first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102785 C5S_RS0102790 C5S_RS0102790 C5S_RS0102790 572339 573025 - ribulose-phosphate 3-epimerase gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102790 C5S_RS0102795 C5S_RS0102795 aroB aroB 573908 574999 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102795 C5S_RS0102800 C5S_RS0102800 aroK aroK 575017 575538 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102800 C5S_RS0102805 C5S_RS0102805 C5S_RS0102805 576039 576123 + tRNA-Ser tRNA gene546 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102805 C5S_RS0102810 C5S_RS0102810 C5S_RS0102810 576141 576845 - purine nucleoside phosphorylase gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102810 C5S_RS0102815 C5S_RS0102815 C5S_RS0102815 576889 578112 - phosphopentomutase gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102815 C5S_RS0102820 C5S_RS0102820 prfC prfC 578172 579752 - peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102820 C5S_RS0102825 C5S_RS0102825 C5S_RS0102825 580864 581442 - fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102825 C5S_RS0102830 C5S_RS0102830 C5S_RS0102830 582225 582740 - single-stranded DNA-binding protein gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102830 C5S_RS0102835 C5S_RS0102835 C5S_RS0102835 583410 584807 + replicative DNA helicase unwinds double stranded DNA gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102835 C5S_RS0102840 C5S_RS0102840 C5S_RS0102840 585054 586016 + glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102840 C5S_RS0102845 C5S_RS0102845 C5S_RS0102845 586027 586434 + Holliday junction DNA helicase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102845 C5S_RS0102850 C5S_RS0102850 C5S_RS0102850 586552 587154 + YggS family pyridoxal phosphate enzyme gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102850 C5S_RS0102855 C5S_RS0102855 C5S_RS0102855 587197 588327 + coproporphyrinogen III oxidase gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102855 C5S_RS0102860 C5S_RS0102860 trmB trmB 588334 589053 - tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102860 C5S_RS0102865 C5S_RS0102865 C5S_RS0102865 589151 590203 + A/G-specific adenine glycosylase gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102865 C5S_RS0102870 C5S_RS0102870 C5S_RS0102870 590223 590456 + Fe(2+)-trafficking protein gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102870 C5S_RS0102875 C5S_RS0102875 C5S_RS0102875 590550 591338 + glutamate racemase gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102875 C5S_RS0102880 C5S_RS0102880 C5S_RS0102880 591335 592852 - exonuclease gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102880 C5S_RS0102885 C5S_RS0102885 C5S_RS0102885 592851 593159 + hypothetical protein gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102885 C5S_RS0102890 C5S_RS0102890 C5S_RS0102890 593168 593240 - tRNA-Asn tRNA gene563 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102890 C5S_RS0102895 C5S_RS0102895 C5S_RS0102895 593374 593446 + tRNA-Met tRNA gene564 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102895 C5S_RS0102900 C5S_RS0102900 pyrE pyrE 593540 594181 + orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102900 C5S_RS0102905 C5S_RS0102905 C5S_RS0102905 594193 594657 - deoxyuridine 5'-triphosphate nucleotidohydrolase gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102905 C5S_RS0102910 C5S_RS0102910 C5S_RS0102910 594701 595450 - adenosine-3'(2')%2C5'-bisphosphate nucleotidase catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102910 C5S_RS0102915 C5S_RS0102915 rplI rplI 595485 595937 - 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102915 C5S_RS0102920 C5S_RS0102920 rpsR rpsR 595986 596213 - 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102920 C5S_RS0102925 C5S_RS0102925 C5S_RS0102925 596339 596680 - 30S ribosomal protein S6 gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102925 C5S_RS0102930 C5S_RS0102930 C5S_RS0102930 596846 599041 - ribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102930 C5S_RS0102935 C5S_RS0102935 C5S_RS0102935 599171 600472 - adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102935 C5S_RS0102940 C5S_RS0102940 C5S_RS0102940 600522 601454 - protein HflC with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102940 C5S_RS0102945 C5S_RS0102945 C5S_RS0102945 601457 602677 - protein HflK with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102945 C5S_RS0102950 C5S_RS0102950 miaA miaA 602834 603742 - tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102950 C5S_RS0102955 C5S_RS0102955 C5S_RS0102955 603780 605534 - DNA mismatch repair protein MutL gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102955 C5S_RS0102960 C5S_RS0102960 C5S_RS0102960 605634 606791 - mannitol-1-phosphate 5-dehydrogenase gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102960 C5S_RS0102965 C5S_RS0102965 C5S_RS0102965 606833 608731 - PTS mannitol EIICBA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIC forms the translocation channel and contains the specific substrate-binding site%3B subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit%3B subunit IIB transfers the phosphoryl group to the substrate gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102965 C5S_RS0102970 C5S_RS0102970 pgi pgi 608905 610554 - glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102970 C5S_RS0102980 C5S_RS0102980 C5S_RS0102980 610868 611422 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102980 C5S_RS0102985 C5S_RS0102985 C5S_RS0102985 611510 611585 + tRNA-Gly tRNA gene581 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102985 C5S_RS0102995 C5S_RS0102995 C5S_RS0102995 611875 612588 + N-acetylmuramoyl-L-alanine amidase gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0102995 C5S_RS0103000 C5S_RS0103000 rpmE rpmE 612695 612913 - 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103000 C5S_RS0103015 C5S_RS0103015 C5S_RS0103015 613500 614030 + ATP-dependent protease heat shock protein involved in degradation of misfolded proteins gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103015 C5S_RS0103020 C5S_RS0103020 hslU hslU 614043 615374 + ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103020 C5S_RS0103025 C5S_RS0103025 C5S_RS0103025 615581 616054 + heat-shock protein IbpA gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103025 C5S_RS0103030 C5S_RS0103030 C5S_RS0103030 616131 616889 + ferredoxin--NADP reductase gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103030 C5S_RS0103035 C5S_RS0103035 C5S_RS0103035 616907 617881 - elongation factor P--(R)-beta-lysine ligase gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103035 C5S_RS0103040 C5S_RS0103040 C5S_RS0103040 617952 618449 + phosphopantetheine adenylyltransferase gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103040 C5S_RS0103045 C5S_RS0103045 C5S_RS0103045 618536 619153 - hypothetical protein gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103045 C5S_RS0103050 C5S_RS0103050 C5S_RS0103050 619632 619970 - hypothetical protein gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103050 C5S_RS0103055 C5S_RS0103055 C5S_RS0103055 620126 620866 + ribosomal RNA small subunit methyltransferase J gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103055 C5S_RS0103060 C5S_RS0103060 C5S_RS0103060 620949 622421 - phosphate transporter PitA involved in the transport of inorganic phosphate gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103060 C5S_RS0103065 C5S_RS0103065 C5S_RS0103065 622588 623859 - hypothetical protein gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103065 C5S_RS0103070 C5S_RS0103070 dapF dapF 623840 624694 - diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103070 C5S_RS0103075 C5S_RS0103075 C5S_RS0103075 624883 625233 + protein CyaY gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103075 C5S_RS0103080 C5S_RS0103080 hemC hemC 625362 626306 + porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103080 C5S_RS0103085 C5S_RS0103085 C5S_RS0103085 626303 626650 + uroporphyrinogen III methyltransferase gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103085 C5S_RS0103090 C5S_RS0103090 C5S_RS0103090 626647 627060 + uroporphyrinogen III methyltransferase gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103090 C5S_RS0103095 C5S_RS0103095 C5S_RS0103095 627066 627142 - tRNA-Pro tRNA gene600 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103095 C5S_RS0103100 C5S_RS0103100 C5S_RS0103100 627179 627254 - tRNA-His tRNA gene601 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103100 C5S_RS0103105 C5S_RS0103105 C5S_RS0103105 627284 627357 - tRNA-Arg tRNA gene602 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103105 C5S_RS0103110 C5S_RS0103110 rho rho 627544 628803 - transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103110 C5S_RS0103115 C5S_RS0103115 trxA trxA 628933 629259 - thioredoxin gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103115 C5S_RS0103120 C5S_RS0103120 C5S_RS0103120 629461 631398 - ATP-dependent DNA helicase Rep single-stranded DNA-dependent ATPase%3B initiates unwinding at a nick in the DNA%3B involved in DNA replication gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103120 C5S_RS0103125 C5S_RS0103125 C5S_RS0103125 631468 632943 - ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103125 C5S_RS0103130 C5S_RS0103130 C5S_RS0103130 632988 634841 - dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103130 C5S_RS0103135 C5S_RS0103135 C5S_RS0103135 635086 635159 - tRNA-Trp tRNA gene608 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103135 C5S_RS0103140 C5S_RS0103140 C5S_RS0103140 635330 636544 + cysteine desulfurase IscS gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103140 C5S_RS0103145 C5S_RS0103145 C5S_RS0103145 636575 636958 + Fe-S cluster assembly scaffold IscU gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103145 C5S_RS0103150 C5S_RS0103150 C5S_RS0103150 637053 637577 + co-chaperone protein HscB gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103150 C5S_RS0103155 C5S_RS0103155 C5S_RS0103155 637589 639424 + chaperone protein HscA gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103155 C5S_RS0103160 C5S_RS0103160 C5S_RS0103160 639424 639759 + (2Fe-2S) ferredoxin gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103160 C5S_RS0103165 C5S_RS0103165 C5S_RS0103165 639756 641117 - GTPase Der gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103165 C5S_RS0103170 C5S_RS0103170 C5S_RS0103170 641210 641791 - hypothetical protein gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS0103170 C5S_RS1000000103215 C5S_RS1000000103215 rnpA rnpA 14530 14876 + ribonuclease P protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103215 C5S_RS1000000103220 C5S_RS1000000103220 ddl ddl 235337 236259 - D-alanine--D-alanine ligase D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103220 C5S_RS1000000103225 C5S_RS1000000103225 C5S_RS1000000103225 247063 247315 - cell division protein FtsL gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103225 C5S_RS1000000103230 C5S_RS1000000103230 C5S_RS1000000103230 328626 329863 + hypothetical protein gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103230 C5S_RS1000000103240 C5S_RS1000000103240 C5S_RS1000000103240 495204 498427 + exodeoxyribonuclease V subunit gamma gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103240 C5S_RS1000000103250 C5S_RS1000000103250 C5S_RS1000000103250 483741 484007 + 16S rRNA maturation RNase YbeY gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103250 C5S_RS1000000103255 C5S_RS1000000103255 C5S_RS1000000103255 92993 93365 - bacterial RNase P ncRNA gene89 http://www.ncbi.nlm.nih.gov/gene/?term=C5S_RS1000000103255