locus-tag	class	description
SY91_RS00045	COG0673	inositol 2-dehydrogenase activity
SY91_RS00050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SY91_RS00060	COG1396	sequence-specific DNA binding
SY91_RS00065	COG2814	Major facilitator Superfamily
SY91_RS00070	COG0583	DNA-binding transcription factor activity
SY91_RS00080	COG1702	phosphate starvation-inducible protein PhoH
SY91_RS00090	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
SY91_RS00105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SY91_RS00115	COG0752	glycyl-tRNA synthetase alpha subunit
SY91_RS00120	COG0751	glycine-tRNA ligase activity
SY91_RS00125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SY91_RS00130	COG0204	Acyl-transferase
SY91_RS00155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SY91_RS00180	COG5265	(ABC) transporter
SY91_RS00195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SY91_RS00200	COG1024	Enoyl-CoA hydratase
SY91_RS00205	COG0183	Belongs to the thiolase family
SY91_RS00210	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS00210	COG1024	Enoyl-CoA hydratase
SY91_RS00215	COG1960	acyl-CoA dehydrogenase activity
SY91_RS00230	COG0494	nUDIX hydrolase
SY91_RS00290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SY91_RS00310	COG0251	oxidation-reduction process
SY91_RS00315	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SY91_RS00320	COG0837	glucose binding
SY91_RS00320	COG1737	Transcriptional regulator
SY91_RS00340	COG0477	Major facilitator Superfamily
SY91_RS00365	COG0235	Class ii aldolase
SY91_RS00370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SY91_RS00385	COG0501	Belongs to the peptidase M48B family
SY91_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS00415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SY91_RS00430	COG2409	Drug exporters of the RND superfamily
SY91_RS00440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SY91_RS00465	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS00470	COG0183	Belongs to the thiolase family
SY91_RS00490	COG3663	DNA glycosylase
SY91_RS00495	COG0629	single-stranded DNA binding
SY91_RS00500	COG2814	Major facilitator Superfamily
SY91_RS00525	COG1280	lysine exporter protein (LysE YggA)
SY91_RS00545	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SY91_RS00560	COG1137	ATPase activity
SY91_RS00565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SY91_RS00570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SY91_RS00595	COG1194	a g-specific adenine glycosylase
SY91_RS00610	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
SY91_RS00625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SY91_RS00645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SY91_RS00655	COG0742	ribosomal rna small subunit methyltransferase
SY91_RS00665	COG0625	glutathione transferase activity
SY91_RS00670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SY91_RS00675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SY91_RS00690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SY91_RS00705	COG1294	oxidase, subunit
SY91_RS00725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SY91_RS00725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SY91_RS00730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SY91_RS00735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SY91_RS00740	COG2188	Transcriptional regulator
SY91_RS00745	COG0587	DNA-directed DNA polymerase activity
SY91_RS00760	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SY91_RS00785	COG0840	transmembrane signaling receptor activity
SY91_RS00795	COG1999	signal sequence binding
SY91_RS00805	COG1612	heme a metabolic process
SY91_RS00835	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
SY91_RS00845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SY91_RS00860	COG2226	methyltransferase
SY91_RS00865	COG1040	competence protein
SY91_RS00875	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SY91_RS00895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SY91_RS00905	COG0793	Belongs to the peptidase S41A family
SY91_RS00910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SY91_RS00915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SY91_RS00920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SY91_RS00930	COG0189	ligase activity
SY91_RS00940	COG0004	ammonium transporteR
SY91_RS00950	COG2960	long-chain fatty acid transporting porin activity
SY91_RS00975	COG4191	Histidine kinase
SY91_RS00985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SY91_RS00995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS01000	COG1960	acyl-CoA dehydrogenase activity
SY91_RS01005	COG1960	acyl-CoA dehydrogenase activity
SY91_RS01015	COG0583	DNA-binding transcription factor activity
SY91_RS01020	COG0405	Gamma-glutamyltransferase
SY91_RS01030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS01040	COG4521	taurine ABC transporter
SY91_RS01060	COG0583	DNA-binding transcription factor activity
SY91_RS01065	COG2921	Belongs to the UPF0250 family
SY91_RS01075	COG1686	Belongs to the peptidase S11 family
SY91_RS01105	COG1127	ABC transporter
SY91_RS01110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SY91_RS01115	COG0737	Belongs to the 5'-nucleotidase family
SY91_RS01125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SY91_RS01125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SY91_RS01140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SY91_RS01160	COG1024	Enoyl-CoA hydratase
SY91_RS01215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SY91_RS01220	COG0300	oxidoreductase activity
SY91_RS01225	COG0675	Transposase, IS605 OrfB family
SY91_RS01230	COG0747	negative chemotaxis
SY91_RS01235	COG0488	(ABC) transporter
SY91_RS01250	COG0288	reversible hydration of carbon dioxide
SY91_RS01255	COG0300	oxidoreductase activity
SY91_RS01260	COG3012	SEC-C Motif Domain Protein
SY91_RS01305	COG2199	diguanylate cyclase activity
SY91_RS01305	COG2200	EAL domain
SY91_RS01310	COG0025	NhaP-type Na H and K H
SY91_RS01320	COG0110	maltose O-acetyltransferase activity
SY91_RS01325	COG0625	glutathione transferase activity
SY91_RS01345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SY91_RS01360	COG0583	DNA-binding transcription factor activity
SY91_RS01370	COG0625	glutathione transferase activity
SY91_RS01375	COG0583	DNA-binding transcription factor activity
SY91_RS01380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SY91_RS01385	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SY91_RS01390	COG2080	2 iron, 2 sulfur cluster binding
SY91_RS01405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SY91_RS01430	COG1522	sequence-specific DNA binding
SY91_RS01435	COG0596	Alpha beta hydrolase
SY91_RS01445	COG0583	DNA-binding transcription factor activity
SY91_RS01470	COG1609	Transcriptional regulator
SY91_RS01520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SY91_RS01545	COG0672	)-iron permease
SY91_RS01560	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS01570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SY91_RS01575	COG0174	glutamine synthetase
SY91_RS01590	COG3842	ATPase activity
SY91_RS01595	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS01600	COG1177	transmembrane transport
SY91_RS01610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS01615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS01630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS01650	COG0583	DNA-binding transcription factor activity
SY91_RS01655	COG2233	PERMEase
SY91_RS01660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SY91_RS01665	COG1256	bacterial-type flagellum assembly
SY91_RS01670	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SY91_RS01680	COG1706	bacterial-type flagellum-dependent cell motility
SY91_RS01685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SY91_RS01705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SY91_RS01710	COG1558	bacterial-type flagellum-dependent cell motility
SY91_RS01715	COG1815	bacterial-type flagellum-dependent cell motility
SY91_RS01735	COG0006	proline dipeptidase activity
SY91_RS01760	COG0741	lytic transglycosylase activity
SY91_RS01765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SY91_RS01775	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SY91_RS01780	COG1984	allophanate hydrolase subunit 2
SY91_RS01795	COG4608	Belongs to the ABC transporter superfamily
SY91_RS01800	COG0444	Belongs to the ABC transporter superfamily
SY91_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SY91_RS01810	COG0601	transmembrane transport
SY91_RS01815	COG0747	negative chemotaxis
SY91_RS01830	COG0579	oxidoreductase
SY91_RS01835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SY91_RS01850	COG3568	Endonuclease Exonuclease Phosphatase
SY91_RS01865	COG2197	response regulator
SY91_RS01870	COG0531	amino acid
SY91_RS01885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SY91_RS01905	COG1677	Flagellar hook-basal body complex protein FliE
SY91_RS01950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SY91_RS01970	COG0667	Aldo Keto reductase
SY91_RS01995	COG1560	Kdo2-lipid A biosynthetic process
SY91_RS02000	COG3093	addiction module antidote protein HigA
SY91_RS02010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SY91_RS02020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SY91_RS02030	COG0523	cobalamin synthesis protein
SY91_RS02050	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
SY91_RS02075	COG1309	transcriptional regulator
SY91_RS02085	COG2813	Specifically methylates the guanine in position
SY91_RS02085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SY91_RS02090	COG2814	Major facilitator Superfamily
SY91_RS02100	COG2207	Transcriptional regulator
SY91_RS02105	COG1064	alcohol dehydrogenase
SY91_RS02125	COG0708	Exodeoxyribonuclease III
SY91_RS02130	COG2326	polyphosphate kinase activity
SY91_RS02150	COG1077	Cell shape determining protein MreB Mrl
SY91_RS02165	COG0768	penicillin binding
SY91_RS02170	COG0772	Belongs to the SEDS family
SY91_RS02185	COG0720	synthase
SY91_RS02190	COG0602	queuosine metabolic process
SY91_RS02195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SY91_RS02205	COG2204	response regulator
SY91_RS02210	COG5000	phosphorelay sensor kinase activity
SY91_RS02240	COG0242	peptide deformylase activity
SY91_RS02245	COG0758	DNA mediated transformation
SY91_RS02260	COG0583	DNA-binding transcription factor activity
SY91_RS02265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SY91_RS02295	COG0596	Alpha beta hydrolase
SY91_RS02300	COG1126	abc transporter atp-binding protein
SY91_RS02305	COG0765	amino acid transport
SY91_RS02310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS02325	COG1840	ABC-type Fe3 transport system, periplasmic component
SY91_RS02330	COG3842	ATPase activity
SY91_RS02345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS02355	COG3511	phospholipase C
SY91_RS02360	COG0583	DNA-binding transcription factor activity
SY91_RS02365	COG1620	l-lactate permease
SY91_RS02385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SY91_RS02385	COG2169	Transcriptional regulator
SY91_RS02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SY91_RS02420	COG4251	negative regulation of phosphorylation
SY91_RS02420	COG2203	Gaf domain
SY91_RS02420	COG3706	GGDEF domain
SY91_RS02420	COG5001	Diguanylate cyclase
SY91_RS02450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SY91_RS02470	COG0592	DNA-directed DNA polymerase activity
SY91_RS02515	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SY91_RS02520	COG1403	HNH endonuclease
SY91_RS02545	COG3038	cytochrome b561
SY91_RS02550	COG0753	catalase activity
SY91_RS02595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS02600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SY91_RS02605	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SY91_RS02640	COG1987	bacterial-type flagellum assembly
SY91_RS02645	COG1338	Plays a role in the flagellum-specific transport system
SY91_RS02655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SY91_RS02670	COG1346	cytolysis
SY91_RS02675	COG1380	Effector of murein hydrolase LrgA
SY91_RS02680	COG0583	DNA-binding transcription factor activity
SY91_RS02695	COG2814	Major facilitator Superfamily
SY91_RS02700	COG1846	Transcriptional regulator
SY91_RS02745	COG2165	general secretion pathway protein
SY91_RS02780	COG0523	cobalamin synthesis protein
SY91_RS02810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SY91_RS02810	COG0519	Catalyzes the synthesis of GMP from XMP
SY91_RS02815	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS02825	COG0642	Histidine kinase
SY91_RS02845	COG3186	Phenylalanine-4-hydroxylase
SY91_RS02850	COG1522	sequence-specific DNA binding
SY91_RS02860	COG0583	DNA-binding transcription factor activity
SY91_RS02865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SY91_RS02930	COG1192	Involved in chromosome partitioning
SY91_RS02935	COG1475	DNA binding
SY91_RS02940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SY91_RS02950	COG0356	it plays a direct role in the translocation of protons across the membrane
SY91_RS02975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SY91_RS02990	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS03005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SY91_RS03010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SY91_RS03015	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SY91_RS03015	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SY91_RS03015	COG0506	proline dehydrogenase activity
SY91_RS03020	COG0683	leucine binding
SY91_RS03055	COG1960	acyl-CoA dehydrogenase activity
SY91_RS03065	COG0436	Aminotransferase
SY91_RS03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS03075	COG0277	FAD linked oxidase domain protein
SY91_RS03085	COG0789	Transcriptional regulator
SY91_RS03105	COG0668	transmembrane transport
SY91_RS03110	COG0531	amino acid
SY91_RS03115	COG4303	Ethanolamine ammonia lyase large subunit
SY91_RS03120	COG4302	ethanolamine ammonia-lyase activity
SY91_RS03125	COG0583	DNA-binding transcription factor activity
SY91_RS03140	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS03180	COG1760	l-serine dehydratase
SY91_RS03210	COG0673	inositol 2-dehydrogenase activity
SY91_RS03220	COG0210	DNA helicase
SY91_RS03255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SY91_RS03285	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SY91_RS03290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SY91_RS03290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SY91_RS03310	COG0519	Catalyzes the synthesis of GMP from XMP
SY91_RS03325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SY91_RS03330	COG2916	Histone family protein nucleoid-structuring protein H-NS
SY91_RS03335	COG0438	transferase activity, transferring glycosyl groups
SY91_RS03355	COG1360	Flagellar Motor Protein
SY91_RS03360	COG0745	RESPONSE REGULATOR receiver
SY91_RS03365	COG2198	Histidine kinase
SY91_RS03365	COG0643	Histidine kinase
SY91_RS03375	COG0840	transmembrane signaling receptor activity
SY91_RS03380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SY91_RS03395	COG0745	RESPONSE REGULATOR receiver
SY91_RS03400	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SY91_RS03420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SY91_RS03425	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SY91_RS03440	COG1191	sigma factor activity
SY91_RS03450	COG1950	PFAM Membrane protein of
SY91_RS03455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SY91_RS03500	COG1522	sequence-specific DNA binding
SY91_RS03510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SY91_RS03530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SY91_RS03535	COG2823	Periplasmic or secreted lipoprotein
SY91_RS03555	COG2271	Major facilitator Superfamily
SY91_RS03580	COG0577	efflux transmembrane transporter activity
SY91_RS03590	COG0577	efflux transmembrane transporter activity
SY91_RS03590	COG1136	(ABC) transporter
SY91_RS03610	COG2084	Dehydrogenase
SY91_RS03615	COG1280	lysine exporter protein (LysE YggA)
SY91_RS03620	COG2814	Major facilitator Superfamily
SY91_RS03625	COG0583	DNA-binding transcription factor activity
SY91_RS03630	COG3047	cAMP biosynthetic process
SY91_RS03645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SY91_RS03655	COG1881	PFAM PEBP family protein
SY91_RS03660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SY91_RS03665	COG0280	phosphate acetyltransferase
SY91_RS03665	COG0281	malic enzyme
SY91_RS03685	COG1522	sequence-specific DNA binding
SY91_RS03705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SY91_RS03710	COG2151	metal-sulfur cluster biosynthetic enzyme
SY91_RS03715	COG3396	Phenylacetate-CoA oxygenase
SY91_RS03720	COG3460	Phenylacetate-CoA oxygenase
SY91_RS03725	COG3396	Phenylacetate-CoA oxygenase
SY91_RS03785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SY91_RS03800	COG0081	regulation of translation
SY91_RS03810	COG0222	ribosome binding
SY91_RS03825	COG0514	ATP-dependent DNA helicase (RecQ)
SY91_RS03955	COG0201	protein transport
SY91_RS04000	COG4232	protein-disulfide reductase activity
SY91_RS04020	COG1333	cytochrome c biogenesis protein
SY91_RS04025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SY91_RS04030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SY91_RS04035	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
SY91_RS04085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SY91_RS04090	COG1653	transport
SY91_RS04100	COG0395	ABC-type sugar transport system, permease component
SY91_RS04110	COG0584	glycerophosphoryl diester phosphodiesterase
SY91_RS04125	COG0067	glutamate synthase
SY91_RS04125	COG0070	glutamate synthase
SY91_RS04125	COG0069	glutamate synthase activity
SY91_RS04135	COG1115	amino acid carrier protein
SY91_RS04145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS04150	COG2814	Major facilitator Superfamily
SY91_RS04160	COG4178	(ABC) transporter
SY91_RS04185	COG1127	ABC transporter
SY91_RS04190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SY91_RS04195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SY91_RS04215	COG1131	(ABC) transporter
SY91_RS04220	COG0842	Transport permease protein
SY91_RS04255	COG2095	MarC family integral membrane protein
SY91_RS04305	COG0805	protein transport
SY91_RS04310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SY91_RS04315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SY91_RS04320	COG0723	plastoquinol--plastocyanin reductase activity
SY91_RS04325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SY91_RS04330	COG2857	Cytochrome c1
SY91_RS04335	COG0625	glutathione transferase activity
SY91_RS04340	COG2969	positive regulation of protein catabolic process
SY91_RS04385	COG4128	Pfam Zonular occludens toxin
SY91_RS04420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS04605	COG3422	double-strand break repair
SY91_RS04610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SY91_RS04625	COG1309	transcriptional regulator
SY91_RS04640	COG0443	Heat shock 70 kDa protein
SY91_RS04645	COG1278	Cold shock
SY91_RS04650	COG0531	amino acid
SY91_RS04655	COG3384	dioxygenase
SY91_RS04665	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SY91_RS04670	COG2890	protein-(glutamine-N5) methyltransferase activity
SY91_RS04695	COG0006	proline dipeptidase activity
SY91_RS04700	COG1335	isochorismatase
SY91_RS04710	COG0488	(ABC) transporter
SY91_RS04720	COG0583	DNA-binding transcription factor activity
SY91_RS04745	COG0012	GTP binding
SY91_RS04750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SY91_RS04755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SY91_RS04770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SY91_RS04790	COG0512	Glutamine amidotransferase of anthranilate synthase
SY91_RS04800	COG0546	phosphoglycolate phosphatase activity
SY91_RS04805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SY91_RS04810	COG2967	ApaG domain
SY91_RS04815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SY91_RS04825	COG2050	protein possibly involved in aromatic compounds catabolism
SY91_RS04830	COG1024	Enoyl-CoA hydratase
SY91_RS04845	COG1024	Enoyl-CoA hydratase
SY91_RS04880	COG0243	molybdopterin cofactor binding
SY91_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS04890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS04920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SY91_RS04925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SY91_RS04960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SY91_RS04975	COG0678	peroxiredoxin activity
SY91_RS04980	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SY91_RS05005	COG0494	nUDIX hydrolase
SY91_RS05010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
SY91_RS05025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SY91_RS05040	COG4536	flavin adenine dinucleotide binding
SY91_RS05050	COG0142	geranyltranstransferase activity
SY91_RS05090	COG2095	MarC family integral membrane protein
SY91_RS05095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SY91_RS05100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SY91_RS05115	COG3023	N-Acetylmuramoyl-L-alanine amidase
SY91_RS05145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS05150	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SY91_RS05165	COG0439	Biotin carboxylase
SY91_RS05170	COG0511	ligase activity, forming carbon-carbon bonds
SY91_RS05175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SY91_RS05180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SY91_RS05195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SY91_RS05200	COG3150	esterase
SY91_RS05210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SY91_RS05230	COG1414	Transcriptional regulator
SY91_RS05235	COG3734	2-keto-3-deoxy-galactonokinase
SY91_RS05240	COG0800	Aldolase
SY91_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS05275	COG0284	orotidine-5'-phosphate decarboxylase activity
SY91_RS05285	COG1546	Belongs to the CinA family
SY91_RS05290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SY91_RS05305	COG4290	ribonuclease
SY91_RS05315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SY91_RS05325	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SY91_RS05330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SY91_RS05335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SY91_RS05340	COG0583	DNA-binding transcription factor activity
SY91_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS05350	COG1063	alcohol dehydrogenase
SY91_RS05355	COG2814	Major facilitator Superfamily
SY91_RS05360	COG0583	DNA-binding transcription factor activity
SY91_RS05370	COG1301	dicarboxylic acid transport
SY91_RS05375	COG4266	Belongs to the allantoicase family
SY91_RS05380	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
SY91_RS05385	COG0735	belongs to the Fur family
SY91_RS05390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SY91_RS05415	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
SY91_RS05440	COG1981	membrane
SY91_RS05455	COG0800	Aldolase
SY91_RS05465	COG3265	gluconokinase activity
SY91_RS05485	COG0583	DNA-binding transcription factor activity
SY91_RS05490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SY91_RS05500	COG0765	amino acid transport
SY91_RS05505	COG0765	amino acid transport
SY91_RS05510	COG1126	abc transporter atp-binding protein
SY91_RS05520	COG0121	glutamine amidotransferase
SY91_RS05525	COG0418	dihydroorotase activity
SY91_RS05550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SY91_RS05580	COG0588	phosphoglycerate mutase activity
SY91_RS05615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
SY91_RS05625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SY91_RS05630	COG0006	proline dipeptidase activity
SY91_RS05635	COG0625	glutathione transferase activity
SY91_RS05640	COG0069	glutamate synthase activity
SY91_RS05710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SY91_RS05710	COG3008	intermembrane lipid transfer
SY91_RS05715	COG2995	paraquat-inducible protein a
SY91_RS05730	COG2353	YceI-like domain
SY91_RS05745	COG0793	Belongs to the peptidase S41A family
SY91_RS05750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SY91_RS05755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SY91_RS05760	COG1862	Preprotein translocase
SY91_RS05765	COG0343	queuine tRNA-ribosyltransferase activity
SY91_RS05775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SY91_RS05795	COG0783	Belongs to the Dps family
SY91_RS05815	COG0247	lactate metabolic process
SY91_RS05820	COG0277	FAD linked oxidase domain protein
SY91_RS05825	COG0277	FAD linked oxidase domain protein
SY91_RS05830	COG0277	FAD linked oxidase domain protein
SY91_RS05835	COG2096	Adenosyltransferase
SY91_RS05845	COG3744	PilT protein domain protein
SY91_RS05855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SY91_RS05860	COG0312	modulator of DNA gyrase
SY91_RS05865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SY91_RS05875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SY91_RS05880	COG0497	DNA recombination
SY91_RS05910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SY91_RS05930	COG0512	Glutamine amidotransferase of anthranilate synthase
SY91_RS05930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SY91_RS05950	COG0617	tRNA 3'-terminal CCA addition
SY91_RS05960	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SY91_RS05965	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SY91_RS05985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SY91_RS05990	COG0586	Pfam SNARE associated Golgi protein
SY91_RS06025	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SY91_RS06025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SY91_RS06050	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SY91_RS06100	COG0300	oxidoreductase activity
SY91_RS06115	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SY91_RS06120	COG0156	8-amino-7-oxononanoate synthase activity
SY91_RS06130	COG0529	Catalyzes the synthesis of activated sulfate
SY91_RS06140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS06150	COG4682	membrane
SY91_RS06190	COG0824	Thioesterase
SY91_RS06195	COG4221	oxidoreductase activity
SY91_RS06250	COG0450	alkyl hydroperoxide reductase
SY91_RS06255	COG1960	acyl-CoA dehydrogenase activity
SY91_RS06285	COG2814	Major facilitator Superfamily
SY91_RS06305	COG2814	Major facilitator Superfamily
SY91_RS06310	COG0778	Nitroreductase
SY91_RS06315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SY91_RS06320	COG0583	DNA-binding transcription factor activity
SY91_RS06330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SY91_RS06335	COG4977	sequence-specific DNA binding
SY91_RS06365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SY91_RS06405	COG0730	response to heat
SY91_RS06415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SY91_RS06435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS06480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SY91_RS06495	COG1773	rubredoxin
SY91_RS06515	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SY91_RS06525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SY91_RS06575	COG1216	Glycosyl transferase, family 2
SY91_RS06575	COG0438	transferase activity, transferring glycosyl groups
SY91_RS06585	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SY91_RS06620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SY91_RS06635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SY91_RS06640	COG0438	transferase activity, transferring glycosyl groups
SY91_RS06715	COG3842	ATPase activity
SY91_RS06725	COG0559	Belongs to the binding-protein-dependent transport system permease family
SY91_RS06740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SY91_RS06750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SY91_RS06785	COG4948	Mandelate Racemase Muconate Lactonizing
SY91_RS06795	COG0583	DNA-binding transcription factor activity
SY91_RS06800	COG2814	Major facilitator Superfamily
SY91_RS06805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS06810	COG1024	Enoyl-CoA hydratase
SY91_RS06830	COG0494	nUDIX hydrolase
SY91_RS06840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SY91_RS06860	COG0762	integral membrane protein
SY91_RS06890	COG0436	Aminotransferase
SY91_RS06920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SY91_RS06920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SY91_RS06935	COG2814	Major facilitator Superfamily
SY91_RS06965	COG0363	glucosamine-6-phosphate deaminase activity
SY91_RS06970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SY91_RS06980	COG1175	transmembrane transport
SY91_RS06985	COG0395	ABC-type sugar transport system, permease component
SY91_RS06990	COG3842	ATPase activity
SY91_RS07005	COG2860	membrane
SY91_RS07010	COG1193	negative regulation of DNA recombination
SY91_RS07015	COG0492	ferredoxin-NADP+ reductase activity
SY91_RS07020	COG1674	ftsk spoiiie
SY91_RS07025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SY91_RS07030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SY91_RS07050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS07065	COG2894	cell division
SY91_RS07085	COG0859	PFAM glycosyl transferase family 9
SY91_RS07095	COG0477	Major facilitator Superfamily
SY91_RS07120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SY91_RS07125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SY91_RS07135	COG1561	YicC-like family, N-terminal region
SY91_RS07150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SY91_RS07175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS07185	COG1278	Cold shock
SY91_RS07210	COG4772	TonB-dependent receptor
SY91_RS07235	COG0308	aminopeptidase N
SY91_RS07245	COG2119	membrane
SY91_RS07250	COG0402	S-adenosylhomocysteine deaminase activity
SY91_RS07260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SY91_RS07275	COG0154	amidase activity
SY91_RS07285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SY91_RS07320	COG3383	formate dehydrogenase (NAD+) activity
SY91_RS07335	COG1910	domain protein
SY91_RS07355	COG0546	phosphoglycolate phosphatase activity
SY91_RS07360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SY91_RS07390	COG0287	Prephenate dehydrogenase
SY91_RS07420	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SY91_RS07430	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SY91_RS07450	COG2951	lytic endotransglycosylase activity
SY91_RS07455	COG0123	including yeast histone deacetylase and acetoin utilization protein
SY91_RS07460	COG2267	carboxylic ester hydrolase activity
SY91_RS07470	COG2011	ABC-type metal ion transport system permease component
SY91_RS07555	COG0501	Belongs to the peptidase M48B family
SY91_RS07565	COG0521	Mo-molybdopterin cofactor biosynthetic process
SY91_RS07575	COG0312	modulator of DNA gyrase
SY91_RS07590	COG2204	response regulator
SY91_RS07595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SY91_RS07620	COG0114	fumarate hydratase activity
SY91_RS07630	COG2501	S4 domain
SY91_RS07660	COG3045	CreA protein
SY91_RS07675	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SY91_RS07700	COG1322	Protein conserved in bacteria
SY91_RS07715	COG0303	'Molybdopterin
SY91_RS07725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SY91_RS07730	COG1530	ribonuclease E activity
SY91_RS07740	COG0546	phosphoglycolate phosphatase activity
SY91_RS07750	COG0616	signal peptide processing
SY91_RS07765	COG1399	metal-binding, possibly nucleic acid-binding protein
SY91_RS07800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SY91_RS07810	COG1595	DNA-templated transcription, initiation
SY91_RS07825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SY91_RS07840	COG0681	Belongs to the peptidase S26 family
SY91_RS07845	COG0571	ribonuclease III activity
SY91_RS07850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SY91_RS07875	COG2204	response regulator
SY91_RS08025	COG0740	serine-type endopeptidase activity
SY91_RS08205	COG0596	Alpha beta hydrolase
SY91_RS08225	COG0024	Methionine aminopeptidase
SY91_RS08230	COG1956	GAF domain-containing protein
SY91_RS08245	COG2153	protein acetylation
SY91_RS08260	COG1999	signal sequence binding
SY91_RS08270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SY91_RS08275	COG1132	(ABC) transporter
SY91_RS08280	COG0438	transferase activity, transferring glycosyl groups
SY91_RS08310	COG3511	phospholipase C
SY91_RS08320	COG0596	Alpha beta hydrolase
SY91_RS08325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS08335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SY91_RS08340	COG3394	polysaccharide catabolic process
SY91_RS08385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SY91_RS08455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS08465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS08480	COG0004	ammonium transporteR
SY91_RS08495	COG1959	2 iron, 2 sulfur cluster binding
SY91_RS08505	COG1522	sequence-specific DNA binding
SY91_RS08510	COG3842	ATPase activity
SY91_RS08515	COG1178	ABC-type Fe3 transport system permease component
SY91_RS08520	COG1840	ABC-type Fe3 transport system, periplasmic component
SY91_RS08535	COG1289	transmembrane transporter activity
SY91_RS08540	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SY91_RS08545	COG1074	ATP-dependent DNA helicase activity
SY91_RS08550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SY91_RS08560	COG2200	EAL domain
SY91_RS08590	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SY91_RS08595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SY91_RS08610	COG0697	spore germination
SY91_RS08615	COG2814	Major facilitator Superfamily
SY91_RS08620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SY91_RS08625	COG3842	ATPase activity
SY91_RS08630	COG1177	transmembrane transport
SY91_RS08635	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SY91_RS08640	COG1840	ABC-type Fe3 transport system, periplasmic component
SY91_RS08645	COG1609	Transcriptional regulator
SY91_RS08690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SY91_RS08745	COG1396	sequence-specific DNA binding
SY91_RS08865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SY91_RS08915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SY91_RS08925	COG0022	dehydrogenase e1 component
SY91_RS08940	COG0702	epimerase
SY91_RS08950	COG0010	Belongs to the arginase family
SY91_RS08955	COG0456	acetyltransferase
SY91_RS08960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SY91_RS08970	COG0583	DNA-binding transcription factor activity
SY91_RS08975	COG0477	Major facilitator Superfamily
SY91_RS08990	COG2814	Major facilitator Superfamily
SY91_RS08995	COG0583	DNA-binding transcription factor activity
SY91_RS09010	COG0583	DNA-binding transcription factor activity
SY91_RS09015	COG1253	flavin adenine dinucleotide binding
SY91_RS09035	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS09045	COG0583	DNA-binding transcription factor activity
SY91_RS09065	COG3052	prosthetic group binding
SY91_RS09085	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SY91_RS09130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SY91_RS09135	COG0328	RNA-DNA hybrid ribonuclease activity
SY91_RS09140	COG2226	methyltransferase
SY91_RS09145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SY91_RS09160	COG0505	Belongs to the CarA family
SY91_RS09170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SY91_RS09175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SY91_RS09185	COG1534	Rna-binding protein
SY91_RS09195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SY91_RS09210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SY91_RS09215	COG0573	inorganic phosphate transmembrane transporter activity
SY91_RS09220	COG0581	inorganic phosphate transmembrane transporter activity
SY91_RS09235	COG0745	RESPONSE REGULATOR receiver
SY91_RS09290	COG0534	Mate efflux family protein
SY91_RS09300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SY91_RS09305	COG4942	peptidase
SY91_RS09325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SY91_RS09355	COG1215	transferase activity, transferring glycosyl groups
SY91_RS09375	COG1960	acyl-CoA dehydrogenase activity
SY91_RS09385	COG1695	Transcriptional regulator
SY91_RS09390	COG0446	pyridine nucleotide-disulphide oxidoreductase
SY91_RS09390	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS09405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SY91_RS09415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SY91_RS09420	COG2205	protein histidine kinase activity
SY91_RS09425	COG0745	RESPONSE REGULATOR receiver
SY91_RS09445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS09450	COG1595	DNA-templated transcription, initiation
SY91_RS09470	COG0583	DNA-binding transcription factor activity
SY91_RS09480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SY91_RS09485	COG0583	DNA-binding transcription factor activity
SY91_RS09490	COG2851	Citrate transporter
SY91_RS09575	COG4589	Belongs to the CDS family
SY91_RS09590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SY91_RS09595	COG2267	carboxylic ester hydrolase activity
SY91_RS09600	COG2453	phosphatase
SY91_RS09600	COG0671	phosphoesterase, PA-phosphatase related
SY91_RS09615	COG1215	transferase activity, transferring glycosyl groups
SY91_RS09620	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SY91_RS09645	COG1215	transferase activity, transferring glycosyl groups
SY91_RS09650	COG2194	sulfuric ester hydrolase activity
SY91_RS09670	COG1741	Belongs to the pirin family
SY91_RS09695	COG0583	DNA-binding transcription factor activity
SY91_RS09705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SY91_RS09735	COG1858	cytochrome C peroxidase
SY91_RS09745	COG0494	nUDIX hydrolase
SY91_RS09750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SY91_RS09765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS09770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SY91_RS09780	COG0477	Major facilitator Superfamily
SY91_RS09785	COG2816	NAD+ diphosphatase activity
SY91_RS09790	COG0824	Thioesterase
SY91_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS09820	COG4702	Belongs to the UPF0303 family
SY91_RS09825	COG3718	enzyme involved in inositol metabolism
SY91_RS09835	COG3962	Belongs to the TPP enzyme family
SY91_RS09840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS09855	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS09860	COG1082	Xylose isomerase domain protein TIM barrel
SY91_RS09875	COG0673	inositol 2-dehydrogenase activity
SY91_RS09880	COG1737	Transcriptional regulator
SY91_RS09895	COG0425	Belongs to the sulfur carrier protein TusA family
SY91_RS09905	COG0745	RESPONSE REGULATOR receiver
SY91_RS09925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SY91_RS09930	COG0525	valine-tRNA ligase activity
SY91_RS09935	COG0210	DNA helicase
SY91_RS09940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SY91_RS09945	COG2223	nitrite transmembrane transporter activity
SY91_RS09950	COG0840	transmembrane signaling receptor activity
SY91_RS09975	COG0583	DNA-binding transcription factor activity
SY91_RS09990	COG0277	FAD linked oxidase domain protein
SY91_RS10005	COG1295	ribonuclease BN
SY91_RS10020	COG0477	Major facilitator Superfamily
SY91_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS10075	COG0583	DNA-binding transcription factor activity
SY91_RS10085	COG0251	oxidation-reduction process
SY91_RS10090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SY91_RS10100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SY91_RS10105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SY91_RS10120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SY91_RS10130	COG0776	regulation of translation
SY91_RS10155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SY91_RS10195	COG0583	DNA-binding transcription factor activity
SY91_RS10200	COG0436	Aminotransferase
SY91_RS10205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SY91_RS10220	COG0195	Participates in both transcription termination and antitermination
SY91_RS10220	COG2251	uridine kinase activity
SY91_RS10240	COG2814	Major facilitator Superfamily
SY91_RS10245	COG1566	PFAM secretion protein HlyD family protein
SY91_RS10255	COG1846	Transcriptional regulator
SY91_RS10260	COG1217	gtp-binding protein TYPA
SY91_RS10265	COG0567	Dehydrogenase, E1 component
SY91_RS10270	COG0508	dehydrogenase complex catalyzes the overall conversion of
SY91_RS10275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SY91_RS10280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SY91_RS10330	COG4964	Belongs to the GSP D family
SY91_RS10395	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS10405	COG2814	Major facilitator Superfamily
SY91_RS10430	COG1879	ABC-type sugar transport system periplasmic component
SY91_RS10435	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS10460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS10470	COG0557	exoribonuclease II activity
SY91_RS10475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SY91_RS10480	COG3023	N-Acetylmuramoyl-L-alanine amidase
SY91_RS10490	COG1802	Transcriptional regulator
SY91_RS10500	COG0765	amino acid transport
SY91_RS10505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS10510	COG0167	dihydroorotate dehydrogenase activity
SY91_RS10560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SY91_RS10685	COG0419	ATPase involved in DNA repair
SY91_RS10690	COG1674	ftsk spoiiie
SY91_RS10840	COG5410	chromosome segregation
SY91_RS11090	COG0667	Aldo Keto reductase
SY91_RS11105	COG0583	DNA-binding transcription factor activity
SY91_RS11110	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SY91_RS11115	COG0701	Predicted permease
SY91_RS11155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SY91_RS11160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SY91_RS11165	COG4208	sulfate ABC transporter
SY91_RS11170	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SY91_RS11175	COG0583	DNA-binding transcription factor activity
SY91_RS11185	COG1879	ABC-type sugar transport system periplasmic component
SY91_RS11190	COG1129	ABC transporter
SY91_RS11195	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS11200	COG1609	Transcriptional regulator
SY91_RS11205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS11215	COG2766	serine protein kinase
SY91_RS11220	COG2718	Belongs to the UPF0229 family
SY91_RS11225	COG2719	SpoVR family
SY91_RS11230	COG0477	Major facilitator Superfamily
SY91_RS11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS11240	COG0765	amino acid transport
SY91_RS11245	COG0765	amino acid transport
SY91_RS11250	COG0739	heme binding
SY91_RS11255	COG1309	transcriptional regulator
SY91_RS11265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS11280	COG3188	usher protein
SY91_RS11285	COG3121	Chaperone
SY91_RS11315	COG2175	clavaminate synthase activity
SY91_RS11320	COG1120	ATPase activity
SY91_RS11360	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SY91_RS11365	COG4774	siderophore transport
SY91_RS11390	COG1473	amidohydrolase
SY91_RS11445	COG1671	Belongs to the UPF0178 family
SY91_RS11460	COG0494	nUDIX hydrolase
SY91_RS11470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS11475	COG2851	Citrate transporter
SY91_RS11490	COG3979	chitinase
SY91_RS11525	COG2099	Precorrin-6x reductase
SY91_RS11535	COG2807	transmembrane transport
SY91_RS11540	COG0789	Transcriptional regulator
SY91_RS11545	COG2608	mercury ion transmembrane transporter activity
SY91_RS11550	COG2608	mercury ion transmembrane transporter activity
SY91_RS11560	COG0789	Transcriptional regulator
SY91_RS11585	COG1846	Transcriptional regulator
SY91_RS11600	COG0625	glutathione transferase activity
SY91_RS11615	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS11635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SY91_RS11645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS11650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SY91_RS11665	COG0583	DNA-binding transcription factor activity
SY91_RS11670	COG2271	Major facilitator Superfamily
SY91_RS11680	COG1846	Transcriptional regulator
SY91_RS11700	COG1764	response to oxidative stress
SY91_RS11710	COG4771	TonB-dependent receptor
SY91_RS11715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS11720	COG4172	Belongs to the ABC transporter superfamily
SY91_RS11725	COG4239	(ABC) transporter, permease
SY91_RS11730	COG4174	ABC transporter (Permease)
SY91_RS11735	COG4166	transmembrane transport
SY91_RS11740	COG4771	TonB-dependent receptor
SY91_RS11745	COG1396	sequence-specific DNA binding
SY91_RS11785	COG0598	Magnesium transport protein CorA
SY91_RS11830	COG1609	Transcriptional regulator
SY91_RS11845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS11860	COG2855	membrane
SY91_RS11865	COG0038	chloride channel
SY91_RS11875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS11880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS11915	COG0730	response to heat
SY91_RS11915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SY91_RS11920	COG1177	transmembrane transport
SY91_RS11925	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS11930	COG3842	ATPase activity
SY91_RS11935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SY91_RS11945	COG3047	cAMP biosynthetic process
SY91_RS11950	COG2070	2-Nitropropane dioxygenase
SY91_RS11990	COG1819	glycosyl
SY91_RS12000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SY91_RS12020	COG0488	(ABC) transporter
SY91_RS12030	COG2982	Protein involved in outer membrane biogenesis
SY91_RS12035	COG1122	ATPase activity
SY91_RS12040	COG0390	transport system, permease component
SY91_RS12055	COG0583	DNA-binding transcription factor activity
SY91_RS12060	COG0560	Phosphoserine phosphatase
SY91_RS12065	COG0626	cystathionine gamma-synthase activity
SY91_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS12110	COG0183	Belongs to the thiolase family
SY91_RS12115	COG3243	poly(R)-hydroxyalkanoic acid synthase
SY91_RS12125	COG0564	pseudouridine synthase activity
SY91_RS12135	COG1199	ATP-dependent helicase activity
SY91_RS12150	COG2183	response to ionizing radiation
SY91_RS12160	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SY91_RS12180	COG0330	HflC and HflK could
SY91_RS12185	COG0330	HflC and HflK could
SY91_RS12190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SY91_RS12205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SY91_RS12220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SY91_RS12240	COG0670	Belongs to the BI1 family
SY91_RS12280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS12295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SY91_RS12310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SY91_RS12325	COG3228	Belongs to the MtfA family
SY91_RS12340	COG0534	Mate efflux family protein
SY91_RS12345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SY91_RS12355	COG0022	dehydrogenase e1 component
SY91_RS12360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SY91_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS12370	COG3199	ATP-NAD kinase
SY91_RS12375	COG3284	Transcriptional regulator
SY91_RS12400	COG0542	response to heat
SY91_RS12405	COG1959	2 iron, 2 sulfur cluster binding
SY91_RS12410	COG2346	COG2346, Truncated hemoglobins
SY91_RS12415	COG0314	molybdopterin synthase activity
SY91_RS12420	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SY91_RS12440	COG0436	Aminotransferase
SY91_RS12450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SY91_RS12455	COG2076	Multidrug Resistance protein
SY91_RS12460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SY91_RS12465	COG0463	Glycosyl transferase, family 2
SY91_RS12475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SY91_RS12475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SY91_RS12480	COG0726	polysaccharide deacetylase
SY91_RS12485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SY91_RS12490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SY91_RS12495	COG0791	NLP P60 protein
SY91_RS12500	COG0306	phosphate transporter
SY91_RS12510	COG0305	Participates in initiation and elongation during chromosome replication
SY91_RS12525	COG2965	DNA replication, synthesis of RNA primer
SY91_RS12545	COG0583	DNA-binding transcription factor activity
SY91_RS12550	COG3960	tartronate-semialdehyde synthase activity
SY91_RS12555	COG3622	Belongs to the hyi family
SY91_RS12560	COG2084	Dehydrogenase
SY91_RS12570	COG1652	LysM domain
SY91_RS12575	COG0252	asparaginase activity
SY91_RS12595	COG0438	transferase activity, transferring glycosyl groups
SY91_RS12620	COG0084	hydrolase, TatD family'
SY91_RS12635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SY91_RS12650	COG2153	protein acetylation
SY91_RS12670	COG2203	Gaf domain
SY91_RS12670	COG3706	GGDEF domain
SY91_RS12670	COG5001	Diguanylate cyclase
SY91_RS12670	COG4251	negative regulation of phosphorylation
SY91_RS12685	COG0183	Belongs to the thiolase family
SY91_RS12690	COG1335	isochorismatase
SY91_RS12700	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS12725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SY91_RS12730	COG3153	acetyltransferase
SY91_RS12735	COG0047	phosphoribosylformylglycinamidine synthase activity
SY91_RS12735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SY91_RS12740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS12745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SY91_RS12745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SY91_RS12755	COG4181	ATPase activity
SY91_RS12800	COG1929	Belongs to the glycerate kinase type-1 family
SY91_RS12810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SY91_RS12885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS12895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SY91_RS12900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SY91_RS12905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SY91_RS12950	COG3360	Dodecin
SY91_RS12965	COG2351	hydroxyisourate hydrolase activity
SY91_RS12990	COG4266	Belongs to the allantoicase family
SY91_RS12995	COG3195	allantoin biosynthetic process
SY91_RS12995	COG3648	Uricase
SY91_RS13010	COG1953	Uracil, thiamine, allantoin
SY91_RS13020	COG1619	proteins homologs of microcin C7 resistance protein MccF
SY91_RS13025	COG0590	tRNA wobble adenosine to inosine editing
SY91_RS13040	COG2188	Transcriptional regulator
SY91_RS13045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SY91_RS13060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS13090	COG0456	acetyltransferase
SY91_RS13100	COG2176	DNA-directed DNA polymerase activity
SY91_RS13140	COG0697	spore germination
SY91_RS13145	COG2914	Belongs to the UPF0125 (RnfH) family
SY91_RS13160	COG0330	HflC and HflK could
SY91_RS13180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SY91_RS13190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SY91_RS13210	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
SY91_RS13235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SY91_RS13260	COG0024	Methionine aminopeptidase
SY91_RS13310	COG1393	Belongs to the ArsC family
SY91_RS13320	COG2890	protein-(glutamine-N5) methyltransferase activity
SY91_RS13330	COG0386	Belongs to the glutathione peroxidase family
SY91_RS13335	COG0488	(ABC) transporter
SY91_RS13360	COG0351	phosphomethylpyrimidine kinase
SY91_RS13370	COG1573	uracil-dna glycosylase
SY91_RS13380	COG1214	PFAM Peptidase M22, glycoprotease
SY91_RS13390	COG0513	Belongs to the DEAD box helicase family
SY91_RS13395	COG2224	Isocitrate lyase
SY91_RS13405	COG0583	DNA-binding transcription factor activity
SY91_RS13415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SY91_RS13475	COG1752	Esterase of the alpha-beta hydrolase superfamily
SY91_RS13480	COG0791	NLP P60 protein
SY91_RS13485	COG4172	Belongs to the ABC transporter superfamily
SY91_RS13490	COG4239	(ABC) transporter, permease
SY91_RS13495	COG4174	ABC transporter (Permease)
SY91_RS13515	COG0642	Histidine kinase
SY91_RS13520	COG0745	RESPONSE REGULATOR receiver
SY91_RS13565	COG0527	aspartate kinase activity
SY91_RS13570	COG0037	tRNA processing
SY91_RS13595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SY91_RS13605	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SY91_RS13610	COG1045	serine acetyltransferase
SY91_RS13620	COG0483	inositol monophosphate 1-phosphatase activity
SY91_RS13625	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SY91_RS13660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SY91_RS13665	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SY91_RS13670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SY91_RS13680	COG0180	Tryptophanyl-tRNA synthetase
SY91_RS13685	COG1994	Peptidase M50
SY91_RS13690	COG0009	L-threonylcarbamoyladenylate synthase
SY91_RS13695	COG0613	PHP domain protein
SY91_RS13700	COG0596	Alpha beta hydrolase
SY91_RS13705	COG2833	Protein of unknown function (DUF455)
SY91_RS13715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SY91_RS13725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SY91_RS13750	COG0658	competence protein
SY91_RS13750	COG2333	competence protein COMEC
SY91_RS13755	COG0084	hydrolase, TatD family'
SY91_RS13775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SY91_RS13780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SY91_RS13810	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SY91_RS13815	COG0316	Belongs to the HesB IscA family
SY91_RS13820	COG0822	iron-sulfur transferase activity
SY91_RS13825	COG1104	cysteine desulfurase activity
SY91_RS13835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SY91_RS13855	COG1414	Transcriptional regulator
SY91_RS13870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SY91_RS13880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SY91_RS13890	COG4566	intracellular signal transduction
SY91_RS13905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SY91_RS13910	COG1794	racemase activity, acting on amino acids and derivatives
SY91_RS13930	COG1505	serine-type exopeptidase activity
SY91_RS13940	COG3852	Histidine kinase
SY91_RS13945	COG0174	glutamine synthetase
SY91_RS13955	COG1058	Belongs to the CinA family
SY91_RS13955	COG1546	Belongs to the CinA family
SY91_RS13975	COG1643	Atp-dependent helicase
SY91_RS13980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SY91_RS13980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SY91_RS13990	COG0477	Major facilitator Superfamily
SY91_RS14000	COG1960	acyl-CoA dehydrogenase activity
SY91_RS14005	COG0583	DNA-binding transcription factor activity
SY91_RS14020	COG0174	glutamine synthetase
SY91_RS14025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SY91_RS14050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SY91_RS14065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS14070	COG0736	holo-[acyl-carrier-protein] synthase activity
SY91_RS14080	COG0583	DNA-binding transcription factor activity
SY91_RS14090	COG0415	Belongs to the DNA photolyase family
SY91_RS14205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SY91_RS14235	COG1741	Belongs to the pirin family
SY91_RS14255	COG0672	)-iron permease
SY91_RS14260	COG4633	Protein conserved in bacteria
SY91_RS14270	COG0556	nucleotide-excision repair
SY91_RS14280	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS14285	COG0667	Aldo Keto reductase
SY91_RS14290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SY91_RS14355	COG2866	Carboxypeptidase
SY91_RS14370	COG0436	Aminotransferase
SY91_RS14375	COG0625	glutathione transferase activity
SY91_RS14380	COG1024	Enoyl-CoA hydratase
SY91_RS14385	COG0625	glutathione transferase activity
SY91_RS14400	COG1960	acyl-CoA dehydrogenase activity
SY91_RS14415	COG0494	nUDIX hydrolase
SY91_RS14425	COG1007	ATP synthesis coupled electron transport
SY91_RS14460	COG1034	ATP synthesis coupled electron transport
SY91_RS14470	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
SY91_RS14505	COG0149	triose-phosphate isomerase activity
SY91_RS14510	COG4221	oxidoreductase activity
SY91_RS14510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SY91_RS14510	COG0604	alcohol dehydrogenase
SY91_RS14510	COG3321	synthase
SY91_RS14525	COG0683	leucine binding
SY91_RS14535	COG0288	reversible hydration of carbon dioxide
SY91_RS14540	COG0659	secondary active sulfate transmembrane transporter activity
SY91_RS14550	COG1183	phosphatidylcholine synthase activity
SY91_RS14570	COG0028	Belongs to the TPP enzyme family
SY91_RS14600	COG0438	transferase activity, transferring glycosyl groups
SY91_RS14620	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS14635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SY91_RS14665	COG0745	RESPONSE REGULATOR receiver
SY91_RS14670	COG2205	protein histidine kinase activity
SY91_RS14680	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SY91_RS14685	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SY91_RS14705	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS14720	COG0151	Belongs to the GarS family
SY91_RS14730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SY91_RS14735	COG0799	negative regulation of ribosome biogenesis
SY91_RS14750	COG1530	ribonuclease E activity
SY91_RS14755	COG3171	Protein conserved in bacteria
SY91_RS14790	COG1216	Glycosyl transferase, family 2
SY91_RS14800	COG0859	PFAM glycosyl transferase family 9
SY91_RS14825	COG0513	Belongs to the DEAD box helicase family
SY91_RS14830	COG3895	Periplasmic Protein
SY91_RS14850	COG1674	ftsk spoiiie
SY91_RS14855	COG2706	6-phosphogluconolactonase activity
SY91_RS14860	COG3387	PFAM Glycoside hydrolase 15-related
SY91_RS14870	COG1309	transcriptional regulator
SY91_RS14875	COG2878	Part of a membrane complex involved in electron transport
SY91_RS14880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SY91_RS14905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SY91_RS14915	COG3135	benzoate transporter
SY91_RS14940	COG4106	trans-aconitate 2-methyltransferase activity
SY91_RS14985	COG0697	spore germination
SY91_RS14990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS15000	COG0384	phenazine biosynthesis protein PhzF
SY91_RS15010	COG2059	Chromate
SY91_RS15020	COG0583	DNA-binding transcription factor activity
SY91_RS15040	COG0488	(ABC) transporter
SY91_RS15090	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS15095	COG1309	transcriptional regulator
SY91_RS15120	COG2814	Major facilitator Superfamily
SY91_RS15145	COG1116	anion transmembrane transporter activity
SY91_RS15150	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS15175	COG1741	Belongs to the pirin family
SY91_RS15230	COG1472	Belongs to the glycosyl hydrolase 3 family
SY91_RS15240	COG2827	Endonuclease containing a URI domain
SY91_RS15245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SY91_RS15260	COG2271	Major facilitator Superfamily
SY91_RS15270	COG0596	Alpha beta hydrolase
SY91_RS15290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SY91_RS15295	COG2226	methyltransferase
SY91_RS15305	COG0165	Argininosuccinate lyase
SY91_RS15310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SY91_RS15335	COG0489	protein tyrosine kinase activity
SY91_RS15340	COG3047	cAMP biosynthetic process
SY91_RS15340	COG2885	chlorophyll binding
SY91_RS15365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SY91_RS15385	COG2259	Doxx family
SY91_RS15395	COG1492	cobalamin metabolic process
SY91_RS15405	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SY91_RS15415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SY91_RS15425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SY91_RS15430	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SY91_RS15435	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SY91_RS15440	COG4139	cobalamin transport
SY91_RS15475	COG0583	DNA-binding transcription factor activity
SY91_RS15500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SY91_RS15520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SY91_RS15520	COG1648	precorrin-2 dehydrogenase activity
SY91_RS15525	COG2895	sulfate adenylyltransferase (ATP) activity
SY91_RS15535	COG0175	sulfate reduction
SY91_RS15550	COG0583	DNA-binding transcription factor activity
SY91_RS15570	COG0583	DNA-binding transcription factor activity
SY91_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS15595	COG0583	DNA-binding transcription factor activity
SY91_RS15600	COG4221	oxidoreductase activity
SY91_RS15635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SY91_RS15640	COG0456	acetyltransferase
SY91_RS15675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SY91_RS15680	COG1047	Peptidyl-prolyl cis-trans
SY91_RS15700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SY91_RS15720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SY91_RS15720	COG3264	Mechanosensitive ion channel
SY91_RS15725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SY91_RS15725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SY91_RS15730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SY91_RS15735	COG0196	riboflavin kinase activity
SY91_RS15750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SY91_RS15755	COG0756	dUTP diphosphatase activity
SY91_RS15760	COG1113	amino acid transport
SY91_RS15765	COG0542	response to heat
SY91_RS15780	COG1278	Cold shock
SY91_RS15825	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SY91_RS15835	COG0656	L-ascorbic acid biosynthetic process
SY91_RS15840	COG2188	Transcriptional regulator
SY91_RS15845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS15860	COG2814	Major facilitator Superfamily
SY91_RS15875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SY91_RS15895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SY91_RS15900	COG1570	exodeoxyribonuclease VII activity
SY91_RS15905	COG1663	tetraacyldisaccharide 4'-kinase activity
SY91_RS15915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SY91_RS15930	COG0728	peptidoglycan biosynthetic process
SY91_RS15965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SY91_RS15970	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS15975	COG4974	Belongs to the 'phage' integrase family
SY91_RS15985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SY91_RS15990	COG0802	atpase or kinase
SY91_RS16005	COG1741	Belongs to the pirin family
SY91_RS16015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SY91_RS16025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SY91_RS16035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SY91_RS16050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SY91_RS16055	COG1522	sequence-specific DNA binding
SY91_RS16085	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS16100	COG0246	Mannitol dehydrogenase
SY91_RS16105	COG1070	Carbohydrate kinase
SY91_RS16110	COG2390	Transcriptional regulator
SY91_RS16125	COG0583	DNA-binding transcription factor activity
SY91_RS16130	COG3842	ATPase activity
SY91_RS16135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SY91_RS16145	COG4209	transmembrane transport
SY91_RS16155	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
SY91_RS16160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS16170	COG0735	belongs to the Fur family
SY91_RS16180	COG1121	(ABC) transporter
SY91_RS16185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SY91_RS16190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SY91_RS16200	COG1070	Carbohydrate kinase
SY91_RS16205	COG2233	PERMEase
SY91_RS16215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS16235	COG4977	sequence-specific DNA binding
SY91_RS16255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SY91_RS16270	COG2027	D-alanyl-D-alanine carboxypeptidase
SY91_RS16285	COG0009	L-threonylcarbamoyladenylate synthase
SY91_RS16290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SY91_RS16295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SY91_RS16300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SY91_RS16310	COG0469	pyruvate kinase activity
SY91_RS16315	COG0126	phosphoglycerate kinase activity
SY91_RS16350	COG0429	hydrolase of the alpha beta-hydrolase fold
SY91_RS16360	COG4783	chaperone-mediated protein folding
SY91_RS16415	COG4969	Belongs to the N-Me-Phe pilin family
SY91_RS16420	COG0861	Integral membrane protein TerC family
SY91_RS16425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SY91_RS16440	COG2137	regulation of response to DNA damage stimulus
SY91_RS16445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SY91_RS16470	COG0583	DNA-binding transcription factor activity
SY91_RS16475	COG4977	sequence-specific DNA binding
SY91_RS16495	COG0583	DNA-binding transcription factor activity
SY91_RS16510	COG3813	Protein conserved in bacteria
SY91_RS16515	COG2186	Transcriptional regulator
SY91_RS16520	COG4948	Mandelate Racemase Muconate Lactonizing
SY91_RS16530	COG2863	cytochrome
SY91_RS16540	COG0513	Belongs to the DEAD box helicase family
SY91_RS16600	COG0625	glutathione transferase activity
SY91_RS16625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SY91_RS16705	COG3541	Predicted nucleotidyltransferase
SY91_RS16710	COG1690	Belongs to the RtcB family
SY91_RS16725	COG4650	regulator
SY91_RS16745	COG1104	cysteine desulfurase activity
SY91_RS16755	COG2368	4-hydroxyphenylacetate
SY91_RS16770	COG1073	alpha beta
SY91_RS16770	COG2226	methyltransferase
SY91_RS16790	COG0583	DNA-binding transcription factor activity
SY91_RS16795	COG0583	DNA-binding transcription factor activity
SY91_RS16820	COG1289	transmembrane transporter activity
SY91_RS16825	COG3706	GGDEF domain
SY91_RS16830	COG0833	amino acid
SY91_RS16840	COG0583	DNA-binding transcription factor activity
SY91_RS16910	COG3243	poly(R)-hydroxyalkanoic acid synthase
SY91_RS16925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SY91_RS16935	COG0840	transmembrane signaling receptor activity
SY91_RS16990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SY91_RS17055	COG1566	PFAM secretion protein HlyD family protein
SY91_RS17065	COG0583	DNA-binding transcription factor activity
SY91_RS17100	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS17100	COG0446	pyridine nucleotide-disulphide oxidoreductase
SY91_RS17110	COG0583	DNA-binding transcription factor activity
SY91_RS17115	COG2249	NAD(P)H dehydrogenase (quinone) activity
SY91_RS17250	COG4638	Rieske (2fe-2S)
SY91_RS17255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
SY91_RS17260	COG2146	nitrite reductase [NAD(P)H] activity
SY91_RS17270	COG2733	membrane
SY91_RS17275	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SY91_RS17280	COG3657	addiction module killer protein
SY91_RS17290	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS17295	COG0025	NhaP-type Na H and K H
SY91_RS17300	COG0745	RESPONSE REGULATOR receiver
SY91_RS17305	COG0840	transmembrane signaling receptor activity
SY91_RS17345	COG0307	riboflavin synthase, alpha
SY91_RS17355	COG2837	iron assimilation
SY91_RS17365	COG0583	DNA-binding transcription factor activity
SY91_RS17375	COG1914	H( )-stimulated, divalent metal cation uptake system
SY91_RS17390	COG2130	NADP-dependent
SY91_RS17400	COG0628	permease
SY91_RS17420	COG3795	YCII-related domain
SY91_RS17425	COG3795	YCII-related domain
SY91_RS17435	COG4941	Belongs to the sigma-70 factor family
SY91_RS17440	COG1592	Rubrerythrin
SY91_RS17445	COG0247	lactate metabolic process
SY91_RS17470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SY91_RS17490	COG3206	protein involved in exopolysaccharide biosynthesis
SY91_RS17490	COG0489	protein tyrosine kinase activity
SY91_RS17510	COG0438	transferase activity, transferring glycosyl groups
SY91_RS17515	COG0438	transferase activity, transferring glycosyl groups
SY91_RS17520	COG2814	Major facilitator Superfamily
SY91_RS17535	COG2207	Transcriptional regulator
SY91_RS17535	COG3708	Transcriptional regulator
SY91_RS17550	COG2204	response regulator
SY91_RS17565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS17570	COG5642	Protein of unknown function (DUF2384)
SY91_RS17575	COG5654	RES domain protein
SY91_RS17580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SY91_RS17600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SY91_RS17605	COG0352	thiamine-phosphate diphosphorylase activity
SY91_RS17610	COG1253	flavin adenine dinucleotide binding
SY91_RS17625	COG0583	DNA-binding transcription factor activity
SY91_RS17645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SY91_RS17650	COG4149	molybdate abc transporter
SY91_RS17655	COG0725	ABC transporter, periplasmic molybdate-binding protein
SY91_RS17675	COG1764	response to oxidative stress
SY91_RS17680	COG1846	Transcriptional regulator
SY91_RS17700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SY91_RS17705	COG0667	Aldo Keto reductase
SY91_RS17710	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS17720	COG0583	DNA-binding transcription factor activity
SY91_RS17730	COG1611	Belongs to the LOG family
SY91_RS17740	COG1252	NADH dehydrogenase
SY91_RS17745	COG0412	Dienelactone hydrolase
SY91_RS17765	COG0142	geranyltranstransferase activity
SY91_RS17785	COG2081	HI0933 family
SY91_RS17815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SY91_RS17830	COG3064	Membrane
SY91_RS17845	COG0745	RESPONSE REGULATOR receiver
SY91_RS17855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS17870	COG0753	catalase activity
SY91_RS17915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SY91_RS17940	COG3038	cytochrome b561
SY91_RS17955	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SY91_RS17970	COG3842	ATPase activity
SY91_RS17980	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS17985	COG1177	transmembrane transport
SY91_RS17990	COG2814	Major facilitator Superfamily
SY91_RS18000	COG1515	deoxyribonuclease V activity
SY91_RS18015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SY91_RS18040	COG2188	Transcriptional regulator
SY91_RS18045	COG2009	succinate dehydrogenase
SY91_RS18055	COG1053	succinate dehydrogenase
SY91_RS18060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SY91_RS18065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SY91_RS18070	COG0372	Belongs to the citrate synthase family
SY91_RS18075	COG4977	sequence-specific DNA binding
SY91_RS18095	COG1522	sequence-specific DNA binding
SY91_RS18100	COG0833	amino acid
SY91_RS18110	COG1309	transcriptional regulator
SY91_RS18170	COG0135	phosphoribosylanthranilate isomerase activity
SY91_RS18175	COG0133	tryptophan synthase activity
SY91_RS18185	COG0159	tryptophan synthase activity
SY91_RS18190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SY91_RS18195	COG0285	dihydrofolate synthase activity
SY91_RS18225	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SY91_RS18230	COG2755	lipolytic protein G-D-S-L family
SY91_RS18230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SY91_RS18260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SY91_RS18265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SY91_RS18265	COG2755	lipolytic protein G-D-S-L family
SY91_RS18285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS18290	COG1295	ribonuclease BN
SY91_RS18300	COG0437	4 iron, 4 sulfur cluster binding
SY91_RS18305	COG2864	formate dehydrogenase
SY91_RS18320	COG3276	selenocysteine insertion sequence binding
SY91_RS18335	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SY91_RS18350	COG0583	DNA-binding transcription factor activity
SY91_RS18380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS18390	COG2271	Major facilitator Superfamily
SY91_RS18400	COG1733	regulation of RNA biosynthetic process
SY91_RS18425	COG2233	PERMEase
SY91_RS18450	COG1454	alcohol dehydrogenase
SY91_RS18455	COG2814	Major facilitator Superfamily
SY91_RS18460	COG1982	Orn Lys Arg decarboxylase major
SY91_RS18465	COG1982	Orn Lys Arg decarboxylase major
SY91_RS18470	COG0531	amino acid
SY91_RS18475	COG0583	DNA-binding transcription factor activity
SY91_RS18485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS18495	COG0747	negative chemotaxis
SY91_RS18500	COG2175	clavaminate synthase activity
SY91_RS18515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS18520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS18545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS18565	COG1953	Uracil, thiamine, allantoin
SY91_RS18585	COG2271	Major facilitator Superfamily
SY91_RS18590	COG1846	Transcriptional regulator
SY91_RS18600	COG1335	isochorismatase
SY91_RS18605	COG2309	aminopeptidase activity
SY91_RS18610	COG0596	Alpha beta hydrolase
SY91_RS18615	COG3473	Maleate cis-trans isomerase
SY91_RS18620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SY91_RS18625	COG2080	2 iron, 2 sulfur cluster binding
SY91_RS18630	COG2010	Cytochrome c
SY91_RS18630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SY91_RS18650	COG0477	Major facilitator Superfamily
SY91_RS18675	COG0583	DNA-binding transcription factor activity
SY91_RS18685	COG2203	Gaf domain
SY91_RS18685	COG3706	GGDEF domain
SY91_RS18685	COG4251	negative regulation of phosphorylation
SY91_RS18685	COG5001	Diguanylate cyclase
SY91_RS18725	COG0583	DNA-binding transcription factor activity
SY91_RS18740	COG0400	carboxylic ester hydrolase activity
SY91_RS18745	COG4456	Virulence-associated protein
SY91_RS18760	COG0840	transmembrane signaling receptor activity
SY91_RS18790	COG0477	Major facilitator Superfamily
SY91_RS18795	COG1024	Enoyl-CoA hydratase
SY91_RS18800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SY91_RS18820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS18825	COG0765	amino acid transport
SY91_RS18830	COG1126	abc transporter atp-binding protein
SY91_RS18840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SY91_RS18860	COG3634	alkyl hydroperoxide reductase activity
SY91_RS18915	COG1215	transferase activity, transferring glycosyl groups
SY91_RS18920	COG1649	PFAM Uncharacterised BCR, COG1649
SY91_RS18920	COG0726	polysaccharide deacetylase
SY91_RS18940	COG0583	DNA-binding transcription factor activity
SY91_RS18945	COG2308	Evidence 4 Homologs of previously reported genes of
SY91_RS18970	COG1305	Transglutaminase-like
SY91_RS19000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SY91_RS19005	COG0028	Belongs to the TPP enzyme family
SY91_RS19005	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SY91_RS19040	COG2814	Major facilitator Superfamily
SY91_RS19055	COG0789	Transcriptional regulator
SY91_RS19080	COG0129	dihydroxy-acid dehydratase activity
SY91_RS19085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SY91_RS19095	COG0531	amino acid
SY91_RS19100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SY91_RS19105	COG3938	Belongs to the proline racemase family
SY91_RS19110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS19140	COG0625	glutathione transferase activity
SY91_RS19145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SY91_RS19150	COG2271	Major facilitator Superfamily
SY91_RS19165	COG1858	cytochrome C peroxidase
SY91_RS19175	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SY91_RS19175	COG4106	trans-aconitate 2-methyltransferase activity
SY91_RS19185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SY91_RS19200	COG2271	Major facilitator Superfamily
SY91_RS19215	COG4172	Belongs to the ABC transporter superfamily
SY91_RS19220	COG0747	negative chemotaxis
SY91_RS19230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SY91_RS19255	COG3485	protocatechuate 3,4-dioxygenase
SY91_RS19260	COG3485	protocatechuate 3,4-dioxygenase
SY91_RS19275	COG0583	DNA-binding transcription factor activity
SY91_RS19290	COG0531	amino acid
SY91_RS19295	COG1201	RNA secondary structure unwinding
SY91_RS19310	COG0596	Alpha beta hydrolase
SY91_RS19320	COG1538	Outer membrane efflux protein
SY91_RS19360	COG1739	Uncharacterized protein family UPF0029
SY91_RS19375	COG1472	Belongs to the glycosyl hydrolase 3 family
SY91_RS19400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SY91_RS19450	COG0662	Cupin 2, conserved barrel domain protein
SY91_RS19450	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SY91_RS19475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SY91_RS19485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SY91_RS19500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SY91_RS19510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SY91_RS19510	COG1796	DNA polymerase
SY91_RS19515	COG0686	Belongs to the AlaDH PNT family
SY91_RS19545	COG4651	solute:proton antiporter activity
SY91_RS19545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SY91_RS19565	COG1846	Transcriptional regulator
SY91_RS19580	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS19585	COG3384	dioxygenase
SY91_RS19595	COG3971	2-oxopent-4-enoate hydratase activity
SY91_RS19605	COG2207	Transcriptional regulator
SY91_RS19625	COG3842	ATPase activity
SY91_RS19655	COG0642	Histidine kinase
SY91_RS19675	COG1116	anion transmembrane transporter activity
SY91_RS19685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS19700	COG1960	acyl-CoA dehydrogenase activity
SY91_RS19725	COG1562	ergosterol biosynthetic process
SY91_RS19730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS19740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS19750	COG0583	DNA-binding transcription factor activity
SY91_RS19760	COG1621	beta-fructofuranosidase activity
SY91_RS19780	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS19795	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS19825	COG0642	Histidine kinase
SY91_RS19835	COG1538	Outer membrane efflux protein
SY91_RS19840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS19855	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS19860	COG0840	transmembrane signaling receptor activity
SY91_RS19865	COG1238	metal cluster binding
SY91_RS19870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SY91_RS19875	COG1280	lysine exporter protein (LysE YggA)
SY91_RS19905	COG4221	oxidoreductase activity
SY91_RS19960	COG0697	spore germination
SY91_RS19970	COG0583	DNA-binding transcription factor activity
SY91_RS20005	COG0583	DNA-binding transcription factor activity
SY91_RS20015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS20020	COG0402	S-adenosylhomocysteine deaminase activity
SY91_RS20025	COG0038	chloride channel
SY91_RS20085	COG0765	amino acid transport
SY91_RS20090	COG1126	abc transporter atp-binding protein
SY91_RS20095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS20100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SY91_RS20105	COG1858	cytochrome C peroxidase
SY91_RS20110	COG3511	phospholipase C
SY91_RS20120	COG1522	sequence-specific DNA binding
SY91_RS20130	COG1448	Aminotransferase
SY91_RS20155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SY91_RS20160	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
SY91_RS20185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SY91_RS20235	COG1113	amino acid transport
SY91_RS20265	COG2198	Histidine kinase
SY91_RS20265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS20265	COG0784	Response regulator, receiver
SY91_RS20265	COG2205	protein histidine kinase activity
SY91_RS20325	COG1414	Transcriptional regulator
SY91_RS20330	COG2336	PFAM SpoVT AbrB
SY91_RS20340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SY91_RS20345	COG0477	Major facilitator Superfamily
SY91_RS20355	COG3550	peptidyl-serine autophosphorylation
SY91_RS20370	COG0789	Transcriptional regulator
SY91_RS20375	COG2608	mercury ion transmembrane transporter activity
SY91_RS20380	COG2608	mercury ion transmembrane transporter activity
SY91_RS20390	COG0789	Transcriptional regulator
SY91_RS20430	COG1309	transcriptional regulator
SY91_RS20440	COG2130	NADP-dependent
SY91_RS20470	COG3621	Patatin-like phospholipase
SY91_RS20490	COG1192	Involved in chromosome partitioning
SY91_RS20500	COG3657	addiction module killer protein
SY91_RS20505	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SY91_RS20510	COG4695	Portal protein
SY91_RS20600	COG2885	chlorophyll binding
SY91_RS20610	COG2010	Cytochrome c
SY91_RS20640	COG3608	succinylglutamate desuccinylase aspartoacylase
SY91_RS20655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS20660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS20665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS20670	COG1126	abc transporter atp-binding protein
SY91_RS20680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS20715	COG0840	transmembrane signaling receptor activity
SY91_RS20720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SY91_RS20735	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SY91_RS20765	COG4206	TonB-dependent receptor
SY91_RS20775	COG1522	sequence-specific DNA binding
SY91_RS20830	COG1278	Cold shock
SY91_RS20930	COG1280	lysine exporter protein (LysE YggA)
SY91_RS20955	COG5001	Diguanylate cyclase
SY91_RS20955	COG3300	MHYT domain
SY91_RS20960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SY91_RS20965	COG2186	Transcriptional regulator
SY91_RS20970	COG1312	Catalyzes the dehydration of D-mannonate
SY91_RS20975	COG2271	Major facilitator Superfamily
SY91_RS20980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS20995	COG0392	lysyltransferase activity
SY91_RS20995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SY91_RS21005	COG0583	DNA-binding transcription factor activity
SY91_RS21015	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS21025	COG2146	nitrite reductase [NAD(P)H] activity
SY91_RS21030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SY91_RS21045	COG3707	response regulator
SY91_RS21050	COG1116	anion transmembrane transporter activity
SY91_RS21050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS21055	COG1573	uracil-dna glycosylase
SY91_RS21065	COG0179	Fumarylacetoacetate (FAA) hydrolase
SY91_RS21080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SY91_RS21110	COG1063	alcohol dehydrogenase
SY91_RS21125	COG0667	Aldo Keto reductase
SY91_RS21135	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS21135	COG1024	Enoyl-CoA hydratase
SY91_RS21145	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS21150	COG0387	Pfam Sodium calcium exchanger
SY91_RS21160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SY91_RS21165	COG1609	Transcriptional regulator
SY91_RS21175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SY91_RS21180	COG0583	DNA-binding transcription factor activity
SY91_RS21185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SY91_RS21190	COG2271	Major facilitator Superfamily
SY91_RS21195	COG0583	DNA-binding transcription factor activity
SY91_RS21225	COG0583	DNA-binding transcription factor activity
SY91_RS21230	COG1473	amidohydrolase
SY91_RS21260	COG3179	chitinase
SY91_RS21275	COG2259	Doxx family
SY91_RS21295	COG2373	Large extracellular alpha-helical protein
SY91_RS21300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SY91_RS21320	COG2814	Major facilitator Superfamily
SY91_RS21330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS21335	COG1404	Belongs to the peptidase S8 family
SY91_RS21355	COG0583	DNA-binding transcription factor activity
SY91_RS21380	COG1335	isochorismatase
SY91_RS21385	COG2814	Major facilitator Superfamily
SY91_RS21400	COG0668	transmembrane transport
SY91_RS21405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS21410	COG0243	molybdopterin cofactor binding
SY91_RS21415	COG3781	membrane
SY91_RS21420	COG1289	transmembrane transporter activity
SY91_RS21425	COG0583	DNA-binding transcription factor activity
SY91_RS21430	COG2814	Major facilitator Superfamily
SY91_RS21445	COG4166	transmembrane transport
SY91_RS21455	COG1914	H( )-stimulated, divalent metal cation uptake system
SY91_RS21460	COG2140	Oxalate decarboxylase
SY91_RS21465	COG3550	peptidyl-serine autophosphorylation
SY91_RS21480	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SY91_RS21485	COG0747	negative chemotaxis
SY91_RS21490	COG0601	transmembrane transport
SY91_RS21495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SY91_RS21505	COG4172	Belongs to the ABC transporter superfamily
SY91_RS21510	COG2261	transglycosylase associated protein
SY91_RS21520	COG0583	DNA-binding transcription factor activity
SY91_RS21555	COG0667	Aldo Keto reductase
SY91_RS21560	COG0583	DNA-binding transcription factor activity
SY91_RS21565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS21580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SY91_RS21595	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS21605	COG0583	DNA-binding transcription factor activity
SY91_RS21645	COG0745	RESPONSE REGULATOR receiver
SY91_RS21655	COG0745	RESPONSE REGULATOR receiver
SY91_RS21670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS21715	COG2205	protein histidine kinase activity
SY91_RS21715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS21715	COG2198	Histidine kinase
SY91_RS21715	COG0784	Response regulator, receiver
SY91_RS21725	COG2814	Major facilitator Superfamily
SY91_RS21730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SY91_RS21735	COG0246	Mannitol dehydrogenase
SY91_RS21745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SY91_RS21755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS21760	COG0667	Aldo Keto reductase
SY91_RS21765	COG2207	Transcriptional regulator
SY91_RS21770	COG0583	DNA-binding transcription factor activity
SY91_RS21775	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SY91_RS21780	COG2271	Major facilitator Superfamily
SY91_RS21785	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SY91_RS21805	COG1473	amidohydrolase
SY91_RS21815	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS21825	COG0583	DNA-binding transcription factor activity
SY91_RS21830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SY91_RS21865	COG0840	transmembrane signaling receptor activity
SY91_RS21895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS21900	COG0010	Belongs to the arginase family
SY91_RS21925	COG0596	Alpha beta hydrolase
SY91_RS21940	COG0235	Class ii aldolase
SY91_RS21945	COG1942	4-Oxalocrotonate Tautomerase
SY91_RS21960	COG2902	Dehydrogenase
SY91_RS21965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SY91_RS21990	COG0154	amidase activity
SY91_RS22025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SY91_RS22030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SY91_RS22035	COG0477	Major facilitator Superfamily
SY91_RS22050	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS22060	COG0028	Belongs to the TPP enzyme family
SY91_RS22070	COG1414	Transcriptional regulator
SY91_RS22075	COG1073	alpha beta
SY91_RS22075	COG2226	methyltransferase
SY91_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS22100	COG2146	nitrite reductase [NAD(P)H] activity
SY91_RS22105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS22110	COG1414	Transcriptional regulator
SY91_RS22130	COG1408	metallophosphoesterase
SY91_RS22135	COG0583	DNA-binding transcription factor activity
SY91_RS22160	COG1285	pathogenesis
SY91_RS22175	COG3916	Acyl-homoserine-lactone synthase
SY91_RS22195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SY91_RS22200	COG0516	GMP reductase activity
SY91_RS22200	COG0517	IMP dehydrogenase activity
SY91_RS22210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SY91_RS22225	COG1733	regulation of RNA biosynthetic process
SY91_RS22245	COG0625	glutathione transferase activity
SY91_RS22270	COG0789	Transcriptional regulator
SY91_RS22275	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS22280	COG0583	DNA-binding transcription factor activity
SY91_RS22285	COG1309	transcriptional regulator
SY91_RS22290	COG1252	NADH dehydrogenase
SY91_RS22300	COG1301	dicarboxylic acid transport
SY91_RS22315	COG1116	anion transmembrane transporter activity
SY91_RS22320	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS22345	COG0546	phosphoglycolate phosphatase activity
SY91_RS22355	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS22370	COG1473	amidohydrolase
SY91_RS22405	COG1175	transmembrane transport
SY91_RS22410	COG1653	transport
SY91_RS22440	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS22450	COG2321	neutral zinc metallopeptidase
SY91_RS22495	COG0583	DNA-binding transcription factor activity
SY91_RS22500	COG0477	Major facilitator Superfamily
SY91_RS22515	COG4452	Inner membrane protein CreD
SY91_RS22520	COG2205	protein histidine kinase activity
SY91_RS22525	COG0745	RESPONSE REGULATOR receiver
SY91_RS22570	COG0540	Belongs to the ATCase OTCase family
SY91_RS22580	COG4691	Plasmid stability protein
SY91_RS22630	COG1070	Carbohydrate kinase
SY91_RS22635	COG1063	alcohol dehydrogenase
SY91_RS22640	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS22650	COG1879	ABC-type sugar transport system periplasmic component
SY91_RS22660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SY91_RS22665	COG0840	transmembrane signaling receptor activity
SY91_RS22720	COG2207	Transcriptional regulator
SY91_RS22735	COG0745	RESPONSE REGULATOR receiver
SY91_RS22765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SY91_RS22770	COG1684	flagellar biosynthetic protein fliR
SY91_RS22815	COG1450	Type ii and iii secretion system protein
SY91_RS22820	COG4794	Type iii secretion
SY91_RS22825	COG4789	Type iii secretion
SY91_RS22860	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SY91_RS22870	COG0477	Major facilitator Superfamily
SY91_RS22875	COG3214	Protein conserved in bacteria
SY91_RS22880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SY91_RS22900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SY91_RS22925	COG4115	mRNA cleavage
SY91_RS22930	COG0546	phosphoglycolate phosphatase activity
SY91_RS22945	COG0583	DNA-binding transcription factor activity
SY91_RS22955	COG0697	spore germination
SY91_RS22960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS22970	COG1056	cytidyltransferase-related domain
SY91_RS22970	COG1051	belongs to the nudix hydrolase family
SY91_RS22980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SY91_RS23005	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SY91_RS23035	COG0174	glutamine synthetase
SY91_RS23045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS23065	COG1113	amino acid transport
SY91_RS23080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SY91_RS23100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SY91_RS23110	COG2124	cytochrome p450
SY91_RS23135	COG0454	-acetyltransferase
SY91_RS23155	COG0642	Histidine kinase
SY91_RS23215	COG1077	Cell shape determining protein MreB Mrl
SY91_RS23225	COG2205	protein histidine kinase activity
SY91_RS23230	COG0745	RESPONSE REGULATOR receiver
SY91_RS23235	COG2066	Belongs to the glutaminase family
SY91_RS23280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS23290	COG1538	Outer membrane efflux protein
SY91_RS23295	COG0477	Major facilitator Superfamily
SY91_RS23305	COG1024	Enoyl-CoA hydratase
SY91_RS23310	COG1024	Enoyl-CoA hydratase
SY91_RS23325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SY91_RS23330	COG1960	acyl-CoA dehydrogenase activity
SY91_RS23345	COG0330	HflC and HflK could
SY91_RS23385	COG2252	PERMEase
SY91_RS23400	COG3284	Transcriptional regulator
SY91_RS23435	COG1280	lysine exporter protein (LysE YggA)
SY91_RS23455	COG2814	Major facilitator Superfamily
SY91_RS23480	COG1132	(ABC) transporter
SY91_RS23485	COG2375	cellular response to nickel ion
SY91_RS23485	COG1132	(ABC) transporter
SY91_RS23495	COG3433	isochorismatase activity
SY91_RS23495	COG2226	methyltransferase
SY91_RS23495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SY91_RS23500	COG2226	methyltransferase
SY91_RS23500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SY91_RS23500	COG3433	isochorismatase activity
SY91_RS23510	COG1021	2,3-dihydroxybenzoate-AMP ligase
SY91_RS23530	COG0583	DNA-binding transcription factor activity
SY91_RS23535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SY91_RS23580	COG0583	DNA-binding transcription factor activity
SY91_RS23625	COG3209	COG3209 Rhs family protein
SY91_RS23645	COG2199	diguanylate cyclase activity
SY91_RS23665	COG2186	Transcriptional regulator
SY91_RS23670	COG3618	amidohydrolase
SY91_RS23680	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS23695	COG4948	Mandelate Racemase Muconate Lactonizing
SY91_RS23700	COG0179	Fumarylacetoacetate (FAA) hydrolase
SY91_RS23705	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS23715	COG4221	oxidoreductase activity
SY91_RS23730	COG0657	acetylesterase activity
SY91_RS23740	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS23745	COG3246	L-lysine catabolic process to acetate
SY91_RS23770	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS23790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SY91_RS23805	COG2207	Transcriptional regulator
SY91_RS23830	COG2814	Major facilitator Superfamily
SY91_RS23845	COG3119	arylsulfatase activity
SY91_RS23865	COG2113	Glycine betaine
SY91_RS23875	COG4638	Rieske (2fe-2S)
SY91_RS23885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SY91_RS23890	COG2181	nitrate reductase activity
SY91_RS23890	COG0247	lactate metabolic process
SY91_RS23895	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS23895	COG0446	pyridine nucleotide-disulphide oxidoreductase
SY91_RS23925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS23960	COG2814	Major facilitator Superfamily
SY91_RS23975	COG2267	carboxylic ester hydrolase activity
SY91_RS24030	COG1131	(ABC) transporter
SY91_RS24040	COG0842	Transport permease protein
SY91_RS24045	COG2814	Major facilitator Superfamily
SY91_RS24060	COG3795	YCII-related domain
SY91_RS24070	COG2267	carboxylic ester hydrolase activity
SY91_RS24075	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SY91_RS24100	COG0535	radical SAM domain protein
SY91_RS24110	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
SY91_RS24115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SY91_RS24130	COG3284	Transcriptional regulator
SY91_RS24175	COG0840	transmembrane signaling receptor activity
SY91_RS24195	COG2936	dipeptidyl-peptidase activity
SY91_RS24205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SY91_RS24210	COG1732	Glycine betaine
SY91_RS24215	COG1174	glycine betaine transport
SY91_RS24220	COG1125	glycine betaine transport
SY91_RS24225	COG1174	glycine betaine transport
SY91_RS24245	COG3550	peptidyl-serine autophosphorylation
SY91_RS24265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SY91_RS24265	COG0446	pyridine nucleotide-disulphide oxidoreductase
SY91_RS24280	COG1760	l-serine dehydratase
SY91_RS24290	COG2186	Transcriptional regulator
SY91_RS24295	COG2084	Dehydrogenase
SY91_RS24300	COG3395	kinase activity
SY91_RS24305	COG0235	Class ii aldolase
SY91_RS24310	COG2271	Major facilitator Superfamily
SY91_RS24315	COG3622	Belongs to the hyi family
SY91_RS24320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SY91_RS24350	COG0583	DNA-binding transcription factor activity
SY91_RS24360	COG2860	membrane
SY91_RS24380	COG4175	Glycine betaine
SY91_RS24450	COG0457	Tetratricopeptide repeat
SY91_RS24450	COG0859	PFAM glycosyl transferase family 9
SY91_RS24460	COG3287	FIST C domain
SY91_RS24460	COG2200	EAL domain
SY91_RS24460	COG2199	diguanylate cyclase activity
SY91_RS24475	COG3511	phospholipase C
SY91_RS24490	COG1024	Enoyl-CoA hydratase
SY91_RS24490	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS24495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SY91_RS24500	COG1960	acyl-CoA dehydrogenase activity
SY91_RS24530	COG4774	siderophore transport
SY91_RS24545	COG1280	lysine exporter protein (LysE YggA)
SY91_RS24560	COG0596	Alpha beta hydrolase
SY91_RS24585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS24595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SY91_RS24600	COG2252	PERMEase
SY91_RS24615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS24625	COG2271	Major facilitator Superfamily
SY91_RS24640	COG1196	nuclear chromosome segregation
SY91_RS24640	COG3264	Mechanosensitive ion channel
SY91_RS24645	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS24650	COG0833	amino acid
SY91_RS24655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS24670	COG1349	DNA-binding transcription factor activity
SY91_RS24700	COG1280	lysine exporter protein (LysE YggA)
SY91_RS24720	COG0477	Major facilitator Superfamily
SY91_RS24730	COG0583	DNA-binding transcription factor activity
SY91_RS24750	COG0306	phosphate transporter
SY91_RS24760	COG0477	Major facilitator Superfamily
SY91_RS24805	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS24840	COG2271	Major facilitator Superfamily
SY91_RS24845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SY91_RS24850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SY91_RS24880	COG2259	Doxx family
SY91_RS24895	COG2721	sulfolactate sulfo-lyase activity
SY91_RS24925	COG2271	Major facilitator Superfamily
SY91_RS24950	COG1522	sequence-specific DNA binding
SY91_RS24955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SY91_RS24975	COG0523	cobalamin synthesis protein
SY91_RS24995	COG2011	ABC-type metal ion transport system permease component
SY91_RS25015	COG3493	citrate carrier protein
SY91_RS25020	COG4191	Histidine kinase
SY91_RS25025	COG2204	response regulator
SY91_RS25085	COG0583	DNA-binding transcription factor activity
SY91_RS25120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SY91_RS25130	COG0840	transmembrane signaling receptor activity
SY91_RS25135	COG0840	transmembrane signaling receptor activity
SY91_RS25140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SY91_RS25150	COG1683	Conserved Protein
SY91_RS25155	COG0183	Belongs to the thiolase family
SY91_RS25160	COG1414	Transcriptional regulator
SY91_RS25185	COG1473	amidohydrolase
SY91_RS25235	COG2814	Major facilitator Superfamily
SY91_RS25255	COG3386	PFAM SMP-30 Gluconolaconase
SY91_RS25260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SY91_RS25265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SY91_RS25270	COG1414	Transcriptional regulator
SY91_RS25275	COG1309	transcriptional regulator
SY91_RS25280	COG0604	alcohol dehydrogenase
SY91_RS25295	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS25300	COG1309	transcriptional regulator
SY91_RS25305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SY91_RS25310	COG0583	DNA-binding transcription factor activity
SY91_RS25315	COG2814	Major facilitator Superfamily
SY91_RS25325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS25330	COG0656	L-ascorbic acid biosynthetic process
SY91_RS25335	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS25360	COG2252	PERMEase
SY91_RS25375	COG2814	Major facilitator Superfamily
SY91_RS25385	COG0583	DNA-binding transcription factor activity
SY91_RS25405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS25425	COG4771	TonB-dependent receptor
SY91_RS25430	COG3720	iron ion transport
SY91_RS25435	COG4558	Periplasmic binding protein
SY91_RS25440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SY91_RS25450	COG2860	membrane
SY91_RS25465	COG3257	ureidoglycine aminohydrolase activity
SY91_RS25495	COG0625	glutathione transferase activity
SY91_RS25530	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS25575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS25580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SY91_RS25600	COG2814	Major facilitator Superfamily
SY91_RS25635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SY91_RS25650	COG1271	oxidase subunit
SY91_RS25655	COG1294	oxidase, subunit
SY91_RS25705	COG2217	Heavy metal translocating P-type atpase
SY91_RS25725	COG1285	pathogenesis
SY91_RS25800	COG0657	acetylesterase activity
SY91_RS25855	COG1042	CoA-binding domain protein
SY91_RS25855	COG0045	succinate-CoA ligase (ADP-forming) activity
SY91_RS25855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SY91_RS25860	COG2916	Histone family protein nucleoid-structuring protein H-NS
SY91_RS25880	COG2610	gluconate transmembrane transporter activity
SY91_RS25895	COG1247	-acetyltransferase
SY91_RS25920	COG4608	Belongs to the ABC transporter superfamily
SY91_RS25930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SY91_RS25935	COG0601	transmembrane transport
SY91_RS25950	COG3104	oligopeptide transport
SY91_RS25975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SY91_RS25995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SY91_RS26025	COG1272	protein, Hemolysin III
SY91_RS26030	COG2879	small protein
SY91_RS26035	COG1966	Carbon starvation protein
SY91_RS26040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SY91_RS26045	COG1595	DNA-templated transcription, initiation
SY91_RS26050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS26060	COG0583	DNA-binding transcription factor activity
SY91_RS26070	COG1764	response to oxidative stress
SY91_RS26085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SY91_RS26100	COG3132	Protein of unknown function, DUF480
SY91_RS26105	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS26110	COG2258	MOSC domain
SY91_RS26115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SY91_RS26120	COG0235	Class ii aldolase
SY91_RS26125	COG1396	sequence-specific DNA binding
SY91_RS26130	COG2188	Transcriptional regulator
SY91_RS26190	COG1473	amidohydrolase
SY91_RS26200	COG1522	sequence-specific DNA binding
SY91_RS26210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS26215	COG2814	Major facilitator Superfamily
SY91_RS26220	COG3320	Male sterility
SY91_RS26220	COG1022	Amp-dependent synthetase and ligase
SY91_RS26225	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS26230	COG1024	Enoyl-CoA hydratase
SY91_RS26290	COG2186	Transcriptional regulator
SY91_RS26300	COG1609	Transcriptional regulator
SY91_RS26320	COG1175	transmembrane transport
SY91_RS26325	COG0395	ABC-type sugar transport system, permease component
SY91_RS26335	COG0583	DNA-binding transcription factor activity
SY91_RS26345	COG0513	Belongs to the DEAD box helicase family
SY91_RS26355	COG3193	protein, possibly involved in utilization of glycolate and propanediol
SY91_RS26360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SY91_RS26365	COG5001	Diguanylate cyclase
SY91_RS26365	COG2203	Gaf domain
SY91_RS26365	COG4251	negative regulation of phosphorylation
SY91_RS26365	COG3706	GGDEF domain
SY91_RS26375	COG2197	response regulator
SY91_RS26405	COG1233	COG1233 Phytoene dehydrogenase and related
SY91_RS26410	COG1562	ergosterol biosynthetic process
SY91_RS26435	COG3437	response regulator, receiver
SY91_RS26450	COG1595	DNA-templated transcription, initiation
SY91_RS26465	COG1192	Involved in chromosome partitioning
SY91_RS26495	COG1396	sequence-specific DNA binding
SY91_RS26515	COG1309	transcriptional regulator
SY91_RS26530	COG0473	3-isopropylmalate dehydrogenase activity
SY91_RS26535	COG0583	DNA-binding transcription factor activity
SY91_RS26560	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS26570	COG0671	phosphoesterase, PA-phosphatase related
SY91_RS26585	COG1695	Transcriptional regulator
SY91_RS26615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS26620	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS26625	COG1063	alcohol dehydrogenase
SY91_RS26680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SY91_RS26685	COG0589	response to stress
SY91_RS26700	COG1045	serine acetyltransferase
SY91_RS26705	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS26710	COG0302	gtp cyclohydrolase
SY91_RS26740	COG0596	Alpha beta hydrolase
SY91_RS26745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS26750	COG2814	Major facilitator Superfamily
SY91_RS26765	COG1509	lysine 2,3-aminomutase activity
SY91_RS26770	COG1181	Belongs to the D-alanine--D-alanine ligase family
SY91_RS26790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SY91_RS26800	COG0179	Fumarylacetoacetate (FAA) hydrolase
SY91_RS26805	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS26810	COG3047	cAMP biosynthetic process
SY91_RS26845	COG1301	dicarboxylic acid transport
SY91_RS26885	COG1070	Carbohydrate kinase
SY91_RS26900	COG1063	alcohol dehydrogenase
SY91_RS26905	COG0395	ABC-type sugar transport system, permease component
SY91_RS26920	COG2205	protein histidine kinase activity
SY91_RS26925	COG0745	RESPONSE REGULATOR receiver
SY91_RS26935	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS26940	COG2909	trisaccharide binding
SY91_RS26950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SY91_RS26950	COG4221	oxidoreductase activity
SY91_RS26950	COG3321	synthase
SY91_RS26950	COG0604	alcohol dehydrogenase
SY91_RS26990	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS26995	COG1960	acyl-CoA dehydrogenase activity
SY91_RS27010	COG0417	DNA replication proofreading
SY91_RS27055	COG1252	NADH dehydrogenase
SY91_RS27060	COG0583	DNA-binding transcription factor activity
SY91_RS27140	COG2885	chlorophyll binding
SY91_RS27155	COG3135	benzoate transporter
SY91_RS27170	COG0513	Belongs to the DEAD box helicase family
SY91_RS27200	COG0668	transmembrane transport
SY91_RS27205	COG0739	heme binding
SY91_RS27215	COG3038	cytochrome b561
SY91_RS27230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SY91_RS27275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SY91_RS27280	COG2197	response regulator
SY91_RS27290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SY91_RS27295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SY91_RS27325	COG0583	DNA-binding transcription factor activity
SY91_RS27375	COG3206	protein involved in exopolysaccharide biosynthesis
SY91_RS27375	COG0489	protein tyrosine kinase activity
SY91_RS27380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SY91_RS27385	COG1596	polysaccharide export
SY91_RS27390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SY91_RS27415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SY91_RS27440	COG2205	protein histidine kinase activity
SY91_RS27440	COG0784	Response regulator, receiver
SY91_RS27455	COG2197	response regulator
SY91_RS27460	COG2197	response regulator
SY91_RS27465	COG5295	Hep Hag repeat protein
SY91_RS27470	COG0784	Response regulator, receiver
SY91_RS27470	COG2205	protein histidine kinase activity
SY91_RS27475	COG0745	RESPONSE REGULATOR receiver
SY91_RS27485	COG4566	intracellular signal transduction
SY91_RS27500	COG2351	hydroxyisourate hydrolase activity
SY91_RS27510	COG0640	Transcriptional regulator
SY91_RS27520	COG0798	PFAM Bile acid sodium symporter
SY91_RS27525	COG0431	NADPH-dependent FMN reductase
SY91_RS27545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SY91_RS27570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SY91_RS27585	COG5265	(ABC) transporter
SY91_RS27590	COG0667	Aldo Keto reductase
SY91_RS27595	COG0583	DNA-binding transcription factor activity
SY91_RS27615	COG3537	Alpha-1,2-mannosidase
SY91_RS27620	COG3537	Alpha-1,2-mannosidase
SY91_RS27645	COG1522	sequence-specific DNA binding
SY91_RS27660	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
SY91_RS27685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SY91_RS27695	COG0432	Pfam Uncharacterised protein family UPF0047
SY91_RS27700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS27700	COG2205	protein histidine kinase activity
SY91_RS27730	COG2205	protein histidine kinase activity
SY91_RS27730	COG0784	Response regulator, receiver
SY91_RS27735	COG2197	response regulator
SY91_RS27740	COG0784	Response regulator, receiver
SY91_RS27740	COG2205	protein histidine kinase activity
SY91_RS27750	COG3188	usher protein
SY91_RS27755	COG3121	Chaperone
SY91_RS27760	COG3539	Fimbrial protein
SY91_RS27835	COG1596	polysaccharide export
SY91_RS27840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SY91_RS27850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SY91_RS27855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SY91_RS27875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SY91_RS27885	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SY91_RS27890	COG1522	sequence-specific DNA binding
SY91_RS27895	COG0028	Belongs to the TPP enzyme family
SY91_RS27940	COG0583	DNA-binding transcription factor activity
SY91_RS27960	COG0583	DNA-binding transcription factor activity
SY91_RS27980	COG0583	DNA-binding transcription factor activity
SY91_RS27985	COG4106	trans-aconitate 2-methyltransferase activity
SY91_RS28000	COG2271	Major facilitator Superfamily
SY91_RS28010	COG1733	regulation of RNA biosynthetic process
SY91_RS28030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS28190	COG0745	RESPONSE REGULATOR receiver
SY91_RS28195	COG0642	Histidine kinase
SY91_RS28225	COG1522	sequence-specific DNA binding
SY91_RS28235	COG2207	Transcriptional regulator
SY91_RS28250	COG2271	Major facilitator Superfamily
SY91_RS28255	COG1609	Transcriptional regulator
SY91_RS28260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SY91_RS28275	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS28280	COG4774	siderophore transport
SY91_RS28305	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS28315	COG0583	DNA-binding transcription factor activity
SY91_RS28340	COG2197	response regulator
SY91_RS28345	COG3237	CsbD-like
SY91_RS28440	COG1802	Transcriptional regulator
SY91_RS28455	COG0281	malic enzyme
SY91_RS28455	COG0280	phosphate acetyltransferase
SY91_RS28465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS28475	COG0259	pyridoxamine-phosphate oxidase activity
SY91_RS28485	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS28490	COG0596	Alpha beta hydrolase
SY91_RS28535	COG0154	amidase activity
SY91_RS28545	COG1045	serine acetyltransferase
SY91_RS28550	COG1396	sequence-specific DNA binding
SY91_RS28555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SY91_RS28560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SY91_RS28590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SY91_RS28620	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS28630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SY91_RS28635	COG1464	Belongs to the NlpA lipoprotein family
SY91_RS28665	COG2814	Major facilitator Superfamily
SY91_RS28675	COG5001	Diguanylate cyclase
SY91_RS28680	COG1024	Enoyl-CoA hydratase
SY91_RS28705	COG0667	Aldo Keto reductase
SY91_RS28735	COG0625	glutathione transferase activity
SY91_RS28740	COG1011	Hydrolase
SY91_RS28755	COG0583	DNA-binding transcription factor activity
SY91_RS28775	COG0443	Heat shock 70 kDa protein
SY91_RS28790	COG2423	ornithine cyclodeaminase activity
SY91_RS28800	COG1522	sequence-specific DNA binding
SY91_RS28815	COG2072	flavoprotein involved in K transport
SY91_RS28820	COG0583	DNA-binding transcription factor activity
SY91_RS28950	COG1522	sequence-specific DNA binding
SY91_RS28970	COG4566	intracellular signal transduction
SY91_RS28975	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS28980	COG0154	amidase activity
SY91_RS28995	COG1960	acyl-CoA dehydrogenase activity
SY91_RS29000	COG4191	Histidine kinase
SY91_RS29030	COG2271	Major facilitator Superfamily
SY91_RS29040	COG0583	DNA-binding transcription factor activity
SY91_RS29055	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS29070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29085	COG1177	transmembrane transport
SY91_RS29090	COG1176	ABC-type spermidine putrescine transport system, permease component I
SY91_RS29095	COG3842	ATPase activity
SY91_RS29105	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS29150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SY91_RS29160	COG0456	acetyltransferase
SY91_RS29185	COG2885	chlorophyll binding
SY91_RS29195	COG0431	NADPH-dependent FMN reductase
SY91_RS29225	COG2267	carboxylic ester hydrolase activity
SY91_RS29260	COG0583	DNA-binding transcription factor activity
SY91_RS29280	COG1396	sequence-specific DNA binding
SY91_RS29285	COG1285	pathogenesis
SY91_RS29290	COG0517	IMP dehydrogenase activity
SY91_RS29315	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS29320	COG2175	clavaminate synthase activity
SY91_RS29335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS29345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS29355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SY91_RS29360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS29400	COG2814	Major facilitator Superfamily
SY91_RS29405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29430	COG0129	dihydroxy-acid dehydratase activity
SY91_RS29440	COG1733	regulation of RNA biosynthetic process
SY91_RS29445	COG0702	epimerase
SY91_RS29490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29495	COG0251	oxidation-reduction process
SY91_RS29500	COG0683	leucine binding
SY91_RS29525	COG0477	Major facilitator Superfamily
SY91_RS29560	COG0071	Belongs to the small heat shock protein (HSP20) family
SY91_RS29590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SY91_RS29600	COG3958	Transketolase
SY91_RS29605	COG3959	Transketolase, thiamine diphosphate binding domain
SY91_RS29615	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS29620	COG0583	DNA-binding transcription factor activity
SY91_RS29625	COG0583	DNA-binding transcription factor activity
SY91_RS29630	COG1301	dicarboxylic acid transport
SY91_RS29655	COG0702	epimerase
SY91_RS29665	COG1473	amidohydrolase
SY91_RS29675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SY91_RS29710	COG0601	transmembrane transport
SY91_RS29720	COG0840	transmembrane signaling receptor activity
SY91_RS29735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SY91_RS29745	COG1522	sequence-specific DNA binding
SY91_RS29785	COG0477	Major facilitator Superfamily
SY91_RS29810	COG1609	Transcriptional regulator
SY91_RS29815	COG0129	dihydroxy-acid dehydratase activity
SY91_RS29825	COG0583	DNA-binding transcription factor activity
SY91_RS29830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SY91_RS29845	COG0840	transmembrane signaling receptor activity
SY91_RS29850	COG0840	transmembrane signaling receptor activity
SY91_RS29865	COG2721	sulfolactate sulfo-lyase activity
SY91_RS29870	COG0246	Mannitol dehydrogenase
SY91_RS29875	COG1063	alcohol dehydrogenase
SY91_RS29895	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS29905	COG2186	Transcriptional regulator
SY91_RS29915	COG0490	domain, Protein
SY91_RS29915	COG0471	metal ion transport
SY91_RS29935	COG2204	response regulator
SY91_RS29940	COG4191	Histidine kinase
SY91_RS29950	COG4214	carbohydrate transport
SY91_RS29960	COG4213	ABC transporter substrate-binding protein
SY91_RS29965	COG1070	Carbohydrate kinase
SY91_RS29975	COG1609	Transcriptional regulator
SY91_RS29975	COG2207	Transcriptional regulator
SY91_RS29980	COG2017	converts alpha-aldose to the beta-anomer
SY91_RS29985	COG2207	Transcriptional regulator
SY91_RS30005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS30010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS30030	COG0477	Major facilitator Superfamily
SY91_RS30035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS30040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS30075	COG0745	RESPONSE REGULATOR receiver
SY91_RS30080	COG4774	siderophore transport
SY91_RS30100	COG2197	response regulator
SY91_RS30105	COG1129	ABC transporter
SY91_RS30110	COG0411	ABC transporter
SY91_RS30130	COG2271	Major facilitator Superfamily
SY91_RS30135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SY91_RS30165	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS30230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SY91_RS30280	COG4964	Belongs to the GSP D family
SY91_RS30330	COG0463	Glycosyl transferase, family 2
SY91_RS30350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS30355	COG2175	clavaminate synthase activity
SY91_RS30370	COG0583	DNA-binding transcription factor activity
SY91_RS30390	COG0114	fumarate hydratase activity
SY91_RS30415	COG0583	DNA-binding transcription factor activity
SY91_RS30450	COG1278	Cold shock
SY91_RS30455	COG2267	carboxylic ester hydrolase activity
SY91_RS30460	COG1309	transcriptional regulator
SY91_RS30470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SY91_RS30475	COG0346	lactoylglutathione lyase activity
SY91_RS30485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SY91_RS30490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SY91_RS30495	COG2814	Major facilitator Superfamily
SY91_RS30505	COG2084	Dehydrogenase
SY91_RS30525	COG0473	3-isopropylmalate dehydrogenase activity
SY91_RS30540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SY91_RS30565	COG4221	oxidoreductase activity
SY91_RS30575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SY91_RS30580	COG0174	glutamine synthetase
SY91_RS30585	COG1309	transcriptional regulator
SY91_RS30590	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS30595	COG0667	Aldo Keto reductase
SY91_RS30610	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS30615	COG0583	DNA-binding transcription factor activity
SY91_RS30620	COG0583	DNA-binding transcription factor activity
SY91_RS30625	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS30640	COG1116	anion transmembrane transporter activity
SY91_RS30645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS30655	COG4770	biotin carboxylase activity
SY91_RS30675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SY91_RS30690	COG0583	DNA-binding transcription factor activity
SY91_RS30700	COG2205	protein histidine kinase activity
SY91_RS30730	COG1301	dicarboxylic acid transport
SY91_RS30745	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS30750	COG0583	DNA-binding transcription factor activity
SY91_RS30825	COG1301	dicarboxylic acid transport
SY91_RS30835	COG1301	dicarboxylic acid transport
SY91_RS30845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SY91_RS30860	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SY91_RS30865	COG0179	Fumarylacetoacetate (FAA) hydrolase
SY91_RS30885	COG3530	Putative quorum-sensing-regulated virulence factor
SY91_RS30895	COG2885	chlorophyll binding
SY91_RS30900	COG5295	Hep Hag repeat protein
SY91_RS30900	COG5295	Hep Hag repeat protein
SY91_RS30915	COG2205	protein histidine kinase activity
SY91_RS30915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS30925	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS30930	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS30935	COG1129	ABC transporter
SY91_RS30940	COG1879	ABC-type sugar transport system periplasmic component
SY91_RS30955	COG0583	DNA-binding transcription factor activity
SY91_RS30970	COG2267	carboxylic ester hydrolase activity
SY91_RS30975	COG0583	DNA-binding transcription factor activity
SY91_RS30995	COG1136	(ABC) transporter
SY91_RS30995	COG0577	efflux transmembrane transporter activity
SY91_RS31000	COG4591	ABC-type transport system involved in lipoprotein release permease component
SY91_RS31050	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS31060	COG1960	acyl-CoA dehydrogenase activity
SY91_RS31070	COG2226	methyltransferase
SY91_RS31105	COG2706	6-phosphogluconolactonase activity
SY91_RS31115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SY91_RS31120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SY91_RS31175	COG0583	DNA-binding transcription factor activity
SY91_RS31180	COG3268	Saccharopine dehydrogenase
SY91_RS31195	COG0840	transmembrane signaling receptor activity
SY91_RS31215	COG0583	DNA-binding transcription factor activity
SY91_RS31220	COG0583	DNA-binding transcription factor activity
SY91_RS31230	COG0667	Aldo Keto reductase
SY91_RS31235	COG1942	4-Oxalocrotonate Tautomerase
SY91_RS31295	COG0583	DNA-binding transcription factor activity
SY91_RS31315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS31325	COG1538	Outer membrane efflux protein
SY91_RS31365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SY91_RS31405	COG4177	L-phenylalanine transmembrane transporter activity
SY91_RS31420	COG1802	Transcriptional regulator
SY91_RS31470	COG2814	Major facilitator Superfamily
SY91_RS31490	COG2188	Transcriptional regulator
SY91_RS31495	COG2986	histidine ammonia-lyase
SY91_RS31525	COG2259	Doxx family
SY91_RS31545	COG3707	response regulator
SY91_RS31550	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SY91_RS31565	COG2271	Major facilitator Superfamily
SY91_RS31570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS31585	COG0583	DNA-binding transcription factor activity
SY91_RS31590	COG1741	Belongs to the pirin family
SY91_RS31605	COG1346	cytolysis
SY91_RS31610	COG1380	Effector of murein hydrolase LrgA
SY91_RS31625	COG1309	transcriptional regulator
SY91_RS31630	COG1309	transcriptional regulator
SY91_RS31640	COG1132	(ABC) transporter
SY91_RS31675	COG0697	spore germination
SY91_RS31680	COG0683	leucine binding
SY91_RS31690	COG0247	lactate metabolic process
SY91_RS31690	COG0277	FAD linked oxidase domain protein
SY91_RS31695	COG0583	DNA-binding transcription factor activity
SY91_RS31700	COG0583	DNA-binding transcription factor activity
SY91_RS31705	COG1280	lysine exporter protein (LysE YggA)
SY91_RS31710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS31715	COG0431	NADPH-dependent FMN reductase
SY91_RS31725	COG3829	transcription factor binding
SY91_RS31730	COG2376	Dihydroxyacetone kinase
SY91_RS31740	COG0477	Major facilitator Superfamily
SY91_RS31745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SY91_RS31750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SY91_RS31755	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS31760	COG1522	sequence-specific DNA binding
SY91_RS31765	COG3608	succinylglutamate desuccinylase aspartoacylase
SY91_RS31770	COG0006	proline dipeptidase activity
SY91_RS31775	COG2423	ornithine cyclodeaminase activity
SY91_RS31780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SY91_RS31785	COG1725	Transcriptional regulator
SY91_RS31790	COG2301	Belongs to the HpcH HpaI aldolase family
SY91_RS31800	COG1960	acyl-CoA dehydrogenase activity
SY91_RS31805	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
SY91_RS31865	COG0655	NAD(P)H dehydrogenase (quinone) activity
SY91_RS31880	COG4977	sequence-specific DNA binding
SY91_RS31885	COG1192	Involved in chromosome partitioning
SY91_RS31890	COG1475	DNA binding
SY91_RS31905	COG0583	DNA-binding transcription factor activity
SY91_RS31915	COG0583	DNA-binding transcription factor activity
SY91_RS31920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SY91_RS31930	COG0583	DNA-binding transcription factor activity
SY91_RS31935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS31940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SY91_RS31995	COG2233	PERMEase
SY91_RS32005	COG0583	DNA-binding transcription factor activity
SY91_RS32010	COG0405	Gamma-glutamyltransferase
SY91_RS32020	COG0420	3'-5' exonuclease activity
SY91_RS32105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SY91_RS32115	COG0183	Belongs to the thiolase family
SY91_RS32130	COG0493	'glutamate synthase
SY91_RS32140	COG1953	Uracil, thiamine, allantoin
SY91_RS32150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SY91_RS32170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SY91_RS32180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SY91_RS32185	COG0028	Belongs to the TPP enzyme family
SY91_RS32190	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS32240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
SY91_RS32250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SY91_RS32255	COG1012	belongs to the aldehyde dehydrogenase family
SY91_RS32270	COG2207	Transcriptional regulator
SY91_RS32350	COG3546	catalase activity
SY91_RS32355	COG1914	H( )-stimulated, divalent metal cation uptake system
SY91_RS32410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SY91_RS32415	COG0477	Major facilitator Superfamily
SY91_RS32440	COG0583	DNA-binding transcription factor activity
SY91_RS32450	COG1017	nitric oxide dioxygenase activity
SY91_RS32450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SY91_RS32455	COG0625	glutathione transferase activity
SY91_RS32460	COG0745	RESPONSE REGULATOR receiver
SY91_RS32465	COG5002	protein histidine kinase activity
SY91_RS32470	COG2207	Transcriptional regulator
SY91_RS32470	COG4753	response regulator
SY91_RS32480	COG0318	PFAM AMP-dependent synthetase and ligase
SY91_RS32490	COG1960	acyl-CoA dehydrogenase activity
SY91_RS32500	COG0183	Belongs to the thiolase family
SY91_RS32505	COG1250	3-hydroxyacyl-CoA dehydrogenase
SY91_RS32525	COG2207	Transcriptional regulator
SY91_RS32555	COG1349	DNA-binding transcription factor activity
SY91_RS32565	COG0738	Major facilitator superfamily
SY91_RS32570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SY91_RS32585	COG0367	asparagine synthase
SY91_RS32590	COG1538	Outer membrane efflux protein
SY91_RS32595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SY91_RS32620	COG0765	amino acid transport
SY91_RS32625	COG0765	amino acid transport
SY91_RS32660	COG0583	DNA-binding transcription factor activity
SY91_RS32700	COG0583	DNA-binding transcription factor activity
SY91_RS32705	COG1234	tRNA 3'-trailer cleavage
SY91_RS32745	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS32750	COG2814	Major facilitator Superfamily
SY91_RS32755	COG0583	DNA-binding transcription factor activity
SY91_RS32760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SY91_RS32760	COG2010	Cytochrome c
SY91_RS32765	COG2080	2 iron, 2 sulfur cluster binding
SY91_RS32770	COG2010	Cytochrome c
SY91_RS32770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SY91_RS32830	COG0583	DNA-binding transcription factor activity
SY91_RS32870	COG2207	Transcriptional regulator
SY91_RS32875	COG0300	oxidoreductase activity
SY91_RS32885	COG0583	DNA-binding transcription factor activity
SY91_RS32930	COG0589	response to stress
SY91_RS32940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SY91_RS32965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS32980	COG1301	dicarboxylic acid transport
SY91_RS32985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SY91_RS32990	COG2188	Transcriptional regulator
SY91_RS33000	COG0314	molybdopterin synthase activity
SY91_RS33005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SY91_RS33010	COG0303	'Molybdopterin
SY91_RS33015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SY91_RS33020	COG1271	oxidase subunit
SY91_RS33025	COG1294	oxidase, subunit
SY91_RS33030	COG3781	membrane
SY91_RS33065	COG2072	flavoprotein involved in K transport
SY91_RS33085	COG3842	ATPase activity
SY91_RS33090	COG4638	Rieske (2fe-2S)
SY91_RS33095	COG0583	DNA-binding transcription factor activity
SY91_RS33105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS33115	COG0765	amino acid transport
SY91_RS33130	COG0243	molybdopterin cofactor binding
SY91_RS33135	COG0542	response to heat
SY91_RS33150	COG2837	iron assimilation
SY91_RS33175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SY91_RS33185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SY91_RS33200	COG2095	MarC family integral membrane protein
SY91_RS33220	COG2205	protein histidine kinase activity
SY91_RS33235	COG5265	(ABC) transporter
SY91_RS33245	COG0300	oxidoreductase activity
SY91_RS33250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SY91_RS33255	COG0859	PFAM glycosyl transferase family 9
SY91_RS33260	COG2192	nodulation
SY91_RS33270	COG0859	PFAM glycosyl transferase family 9
SY91_RS33280	COG2204	response regulator
SY91_RS33285	COG2204	response regulator
SY91_RS33300	COG2205	protein histidine kinase activity
SY91_RS33305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SY91_RS33310	COG0438	transferase activity, transferring glycosyl groups
SY91_RS33320	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS33335	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS33350	COG1914	H( )-stimulated, divalent metal cation uptake system
SY91_RS33355	COG1573	uracil-dna glycosylase
SY91_RS33415	COG3685	Protein conserved in bacteria
SY91_RS33420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SY91_RS33445	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SY91_RS33475	COG0693	protein deglycase activity
SY91_RS33490	COG0688	phosphatidylethanolamine metabolic process
SY91_RS33505	COG1640	4-alpha-glucanotransferase
SY91_RS33510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SY91_RS33525	COG0366	Alpha amylase catalytic
SY91_RS33530	COG0366	Alpha amylase catalytic
SY91_RS33555	COG1285	pathogenesis
SY91_RS33565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SY91_RS33585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SY91_RS33590	COG0546	phosphoglycolate phosphatase activity
SY91_RS33615	COG1522	sequence-specific DNA binding
SY91_RS33640	COG4178	(ABC) transporter
SY91_RS33645	COG3118	belongs to the thioredoxin family
SY91_RS33650	COG0312	modulator of DNA gyrase
SY91_RS33655	COG0312	modulator of DNA gyrase
SY91_RS33665	COG1595	DNA-templated transcription, initiation
SY91_RS33720	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS33725	COG0251	oxidation-reduction process
SY91_RS33770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SY91_RS33785	COG0028	Belongs to the TPP enzyme family
SY91_RS33835	COG0494	nUDIX hydrolase
SY91_RS33845	COG1566	PFAM secretion protein HlyD family protein
SY91_RS33850	COG2814	Major facilitator Superfamily
SY91_RS33860	COG0745	RESPONSE REGULATOR receiver
SY91_RS33890	COG2824	Alkylphosphonate utilization operon protein PhnA
SY91_RS33920	COG4172	Belongs to the ABC transporter superfamily
SY91_RS33925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SY91_RS33935	COG0747	negative chemotaxis
SY91_RS33945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS33950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS33955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SY91_RS33980	COG1172	Belongs to the binding-protein-dependent transport system permease family
SY91_RS34005	COG3550	peptidyl-serine autophosphorylation
SY91_RS34010	COG1396	sequence-specific DNA binding
SY91_RS34015	COG1285	pathogenesis
SY91_RS34020	COG0517	IMP dehydrogenase activity
SY91_RS34045	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS34050	COG2175	clavaminate synthase activity
SY91_RS34065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SY91_RS34075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SY91_RS34085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SY91_RS34100	COG2916	Histone family protein nucleoid-structuring protein H-NS
SY91_RS34110	COG2801	Transposase and inactivated derivatives
SY91_RS34135	COG2814	Major facilitator Superfamily
SY91_RS34145	COG0179	Fumarylacetoacetate (FAA) hydrolase
SY91_RS34150	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS34165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS34170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SY91_RS34175	COG1902	pentaerythritol trinitrate reductase activity
SY91_RS34180	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SY91_RS34255	COG4974	Belongs to the 'phage' integrase family
SY91_RS34330	COG1487	ribonuclease activity
SY91_RS34335	COG4456	Virulence-associated protein
SY91_RS34360	COG0587	DNA-directed DNA polymerase activity
SY91_RS34390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SY91_RS34395	COG1028	Short-chain dehydrogenase reductase Sdr
SY91_RS34400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SY91_RS34505	COG0587	DNA-directed DNA polymerase activity
SY91_RS34555	COG5295	Hep Hag repeat protein
SY91_RS34790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SY91_RS34795	COG3657	addiction module killer protein